19 CFR 162.13 - Search of rooms not described in warrant.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Search of rooms not described in warrant. 162.13 Section 162.13 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) INSPECTION, SEARCH, AND SEIZURE Search Warrants § 162.13 Search of...

8 CFR 287.3 - Disposition of cases of aliens arrested without warrant.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Disposition of cases of aliens arrested without warrant. 287.3 Section 287.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS; POWERS AND DUTIES § 287.3 Disposition of cases of aliens arrested without warrant...

48 CFR 301.603-71 - Waivers to warrant standards.

Code of Federal Regulations, 2011 CFR

2011-10-01

... of a warrant to an individual who does not fully meet the FAC-C or HHS SAC certification program requirements. Contracting activities shall provide any request for a waiver of the FAC-C program requirements...

48 CFR 301.603-71 - Waivers to warrant standards.

Code of Federal Regulations, 2014 CFR

2014-10-01

... of a warrant to an individual who does not fully meet the FAC-C or HHS SAC certification program requirements. Contracting activities shall provide any request for a waiver of the FAC-C program requirements...

48 CFR 301.603-71 - Waivers to warrant standards.

Code of Federal Regulations, 2013 CFR

2013-10-01

... of a warrant to an individual who does not fully meet the FAC-C or HHS SAC certification program requirements. Contracting activities shall provide any request for a waiver of the FAC-C program requirements...

48 CFR 301.603-71 - Waivers to warrant standards.

Code of Federal Regulations, 2012 CFR

2012-10-01

... of a warrant to an individual who does not fully meet the FAC-C or HHS SAC certification program requirements. Contracting activities shall provide any request for a waiver of the FAC-C program requirements...

17 CFR 270.10f-2 - Exercise of warrants or rights received on portfolio securities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Exercise of warrants or rights... Exercise of warrants or rights received on portfolio securities. Any purchase or other acquisition of securities by a registered investment company pursuant to the exercise of warrants or rights to subscribe to...

17 CFR 270.10f-2 - Exercise of warrants or rights received on portfolio securities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Exercise of warrants or rights... Exercise of warrants or rights received on portfolio securities. Any purchase or other acquisition of securities by a registered investment company pursuant to the exercise of warrants or rights to subscribe to...

17 CFR 270.10f-2 - Exercise of warrants or rights received on portfolio securities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Exercise of warrants or rights... Exercise of warrants or rights received on portfolio securities. Any purchase or other acquisition of securities by a registered investment company pursuant to the exercise of warrants or rights to subscribe to...

17 CFR 270.10f-2 - Exercise of warrants or rights received on portfolio securities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Exercise of warrants or rights... Exercise of warrants or rights received on portfolio securities. Any purchase or other acquisition of securities by a registered investment company pursuant to the exercise of warrants or rights to subscribe to...

17 CFR 270.10f-2 - Exercise of warrants or rights received on portfolio securities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exercise of warrants or rights... Exercise of warrants or rights received on portfolio securities. Any purchase or other acquisition of securities by a registered investment company pursuant to the exercise of warrants or rights to subscribe to...

21 CFR 1316.09 - Application for administrative inspection warrant.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Application for administrative inspection warrant. 1316.09 Section 1316.09 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE ADMINISTRATIVE FUNCTIONS, PRACTICES, AND PROCEDURES Administrative Inspections § 1316.09 Application for...

The Social Construction of Warranting Evidence in Two Classrooms

ERIC Educational Resources Information Center

Weyand, Larkin; Goff, Brent; Newell, George

2018-01-01

This study examines how instructional conversations revealed the ways two teachers' argumentative epistemologies (ideational and social process) shaped literacy events focused on the warranting of evidence. A microethnographic study of the literacy events within each teacher's respective instructional unit revealed that each teacher's epistemology…

The valuation of equity warrants under the fractional Vasicek process of the short-term interest rate

NASA Astrophysics Data System (ADS)

Xiao, Weilin; Zhang, Weiguo; Zhang, Xili; Chen, Xiaoyan

2014-01-01

Motivated by the empirical evidence of long range dependence in short-term interest rates and considering the long maturities of equity warrants, we propose the fractional Vasicek model to describe the dynamics of the short rate in the pricing environment of equity warrants. Using the partial differential equation approach, we present a valuation model for equity warrants under the assumption that the short rate follows the fractional Vasicek process. After identifying the pricing model for equity warrants, we provide the parameter estimation procedure for the proposed pricing model. Since obtaining the values of equity warrants from the proposed model needs to solve a nonlinear equation, we employ a hybrid intelligent algorithm to get around this optimization problem. Furthermore, to illustrate the practicality of our proposed model, we conduct an empirical study to ascertain the performance of our proposed model using the data from China’s warrant market and the China Foreign Exchange Trade System. The comparison of traditional models (such as the Black-Scholes model, the Noreen-Wolfson model, the Lauterbach-Schultz model, and the Ukhov model) with our proposed model is also presented. The empirical results show that the mean absolute percentage error of our pricing model is 10.30%. By contrast, the Black-Scholes model, the Noreen-Wolfson model, the Lauterbach-Schultz model, and the Ukhov model applied to the same warrant produce mean absolute errors of 35.26%, 37.67%, 33.40%, 32.81%, respectively. Thus the long memory property in stochastic interest rates cannot be ignored in determining the valuation of equity warrants.

Crash history after installation of traffic signals : warranted vs. unwarranted.

DOT National Transportation Integrated Search

2008-01-01

The objective of this study was to determine the change in crash history at intersections after installation of a traffic signal. Signals installed based on the warrants from an engineering study resulted in a decrease in angle collisions with an inc...

21 CFR 1316.07 - Requirement for administrative inspection warrant; exceptions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Requirement for administrative inspection warrant; exceptions. 1316.07 Section 1316.07 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE ADMINISTRATIVE FUNCTIONS, PRACTICES, AND PROCEDURES Administrative Inspections § 1316.07 Requirement for...

15 CFR 716.3 - Consent to inspections; warrants for inspections.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Consent to inspections; warrants for inspections. 716.3 Section 716.3 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

15 CFR 716.3 - Consent to inspections; warrants for inspections.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Consent to inspections; warrants for inspections. 716.3 Section 716.3 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

View port to starboard of compartment B127, warrant officers mess ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View port to starboard of compartment B-127, warrant officers mess room. Note sideboard, table and paneling. Port holes to engine room skylight area are on left of photograph. (086) - USS Olympia, Penn's Landing, 211 South Columbus Boulevard, Philadelphia, Philadelphia County, PA

Present investigations of radioactive raw materials by the Geological Survey and a recommended program for future work

USGS Publications Warehouse

Butler, A.P.; Stead, F.W.

1947-01-01

The Geological Survey's program of investigation of radioactive raw materials is presented herewith under present investigations, plans for future investigations, plan of operation, and cost of operation. This report was prepared at the request of the Atomic Energy Commission. Present investigations are summarized to show the scope of the present Trace Elements program, grouping individual projects into related types of investigations. Plans for future investigations on an expanded scale are outlined. These should provide sufficient data and knowledge of the occurrence and availability of uranium, thorium, and related elements, to permit a more complete evaluation of domestic resources. Reconnaissance projects are designed to discover possible new sources of uranium and thorium and to select areas and materials warranting further investigation. Typical projects leading to the estimation of reserves are the investigation of the carnotite ores of the Colorado Plateau by geologic mapping, exploratory drilling, and related research, and investigation of asphaltic sandstone in Emery County, Utah. Extensive research will be undertaken to establish the principles governing the geological and geochemical relations of uranium, thorium, and associated elements as an essential guide in appraising domestic resources. Particular emphasis will be placed on phosphatic rocks and black shales which offer ultimate resources of uranium far greater than carnotite ores. All the foregoing investigations will be accompanied by chemical, gephysical, and mineralogical research and analytical work. Under plan of operation is discussed the organization of the Trace Elements Unit, space requirements for laboratory and office, the scheduling of investigations, and other related problems. The proposed scheduling of work calls for approximately 109, 173, and 203 man years in fiscal years 1948, 1949, and 1950 respectively. Definite plans have been formulated only for the next three fiscal years

28 CFR 2.46 - Execution of warrant and service of summons.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Execution of warrant and service of summons. 2.46 Section 2.46 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND... procedural rights under the Commission's regulations and the possible actions which may be taken by the...

28 CFR 2.46 - Execution of warrant and service of summons.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Execution of warrant and service of summons. 2.46 Section 2.46 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND... procedural rights under the Commission's regulations and the possible actions which may be taken by the...

28 CFR 2.46 - Execution of warrant and service of summons.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Execution of warrant and service of summons. 2.46 Section 2.46 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND... procedural rights under the Commission's regulations and the possible actions which may be taken by the...

28 CFR 2.46 - Execution of warrant and service of summons.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Execution of warrant and service of summons. 2.46 Section 2.46 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND... procedural rights under the Commission's regulations and the possible actions which may be taken by the...

28 CFR 2.46 - Execution of warrant and service of summons.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Execution of warrant and service of summons. 2.46 Section 2.46 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND... procedural rights under the Commission's regulations and the possible actions which may be taken by the...

Preliminary investigations of the winter ecology of Long-billed Curlews in coastal Texas

USGS Publications Warehouse

Woodin, Marc C.; Skoruppa, Mary Kay; Edwardson, Jeremy W.; Austin, Jane E.

2012-01-01

Results from this 1-year pilot study yielded an intriguing combination of findings that warrant further investigation. Observations include reduced numbers of roosting birds along the Texas coast during dry conditions, highly dynamic use of nocturnal roost sites, use of widely divergent habitat types for foraging, low body mass of most captured birds, and apparent fidelity to general feeding areas. Future investigations of this eastern winter population of curlews would benefit from larger sample sizes and monitoring of individual birds.

Warrants, design, and safety of road ranger service patrols : draft final report.

DOT National Transportation Integrated Search

2016-11-01

This research project created a decision support system for managers who must decide if a roadway warrants the addition of the Safety Service Patrol (SSP). Meetings with Florida Department of Transportation (FDOT) service patrol program manager...

41 CFR 301-11.300 - When is actual expense reimbursement warranted?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false When is actual expense reimbursement warranted? 301-11.300 Section 301-11.300 Public Contracts and Property Management Federal Travel... session is held; (b) Costs have escalated because of special events (e.g., missile launching periods...

Renewable Electricity Futures for the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, Trieu; Hand, Maureen; Baldwin, Sam F.

2014-04-14

This paper highlights the key results from the Renewable Electricity (RE) Futures Study. It is a detailed consideration of renewable electricity in the United States. The paper focuses on technical issues related to the operability of the U. S. electricity grid and provides initial answers to important questions about the integration of high penetrations of renewable electricity technologies from a national perspective. The results indicate that the future U. S. electricity system that is largely powered by renewable sources is possible and the further work is warranted to investigate this clean generation pathway. The central conclusion of the analysis ismore » that renewable electricity generation from technologies that are commercially available today, in combination with a more flexible electric system, is more than adequate to supply 80% of the total U. S. electricity generation in 2050 while meeting electricity demand on an hourly basis in every region of the United States.« less

Future Aeronautical Communication Infrastructure Technology Investigation

NASA Technical Reports Server (NTRS)

Gilbert, Tricia; Jin, Jenny; Bergerm Jason; Henriksen, Steven

2008-01-01

This National Aeronautics and Space Administration (NASA) Contractor Report summarizes and documents the work performed to investigate technologies that could support long-term aeronautical mobile communications operating concepts for air traffic management (ATM) in the timeframe of 2020 and beyond, and includes the associated findings and recommendations made by ITT Corporation and NASA Glenn Research Center to the Federal Aviation Administration (FAA). The work was completed as the final phase of a multiyear NASA contract in support of the Future Communication Study (FCS), a cooperative research and development program of the United States FAA, NASA, and EUROCONTROL. This final report focuses on an assessment of final five candidate technologies, and also provides an overview of the entire technology assessment process, including final recommendations.

Unreliable patient identification warrants ABO typing at admission to check existing records before transfusion.

PubMed

Ferrera-Tourenc, V; Lassale, B; Chiaroni, J; Dettori, I

2015-06-01

This study describes patient identification errors leading to transfusional near-misses in blood issued by the Alps Mediterranean French Blood Establishment (EFSAM) to Marseille Public Hospitals (APHM) over an 18-month period. The EFSAM consolidates 14 blood banks in southeast France. It supplies 149 hospitals and maintains a centralized database on ABO types used at all area hospitals. As an added precaution against incompatible transfusion, the APHM requires ABO testing at each admission regardless of whether the patient has an ABO record. The study goal was to determine if admission testing was warranted. Discrepancies between ABO type determined by admission testing and records in the centralized database were investigated. The root cause for each discrepancy was classified as specimen collection or patient admission error. Causes of patient admission events were further subclassified as namesake (name similarity) or impersonation (identity fraud). The incidence of ABO discrepancies was 1:2334 including a 1:3329 incidence of patient admission events. Impersonation was the main cause of identity events accounting for 90.3% of cases. The APHM's ABO control policy prevented 19 incompatible transfusions. In relation to the 48,593 packed red cell units transfused, this would have corresponded to a risk of 1:2526. Collecting and storing ABO typing results in a centralized database is an essential public health tool. It allows crosschecking of current test results with past records and avoids redundant testing. However, as patient identification remains unreliable, ABO typing at each admission is still warranted to prevent transfusion errors. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Amniotic therapeutic biomaterials in urology: current and future applications.

PubMed

Oottamasathien, Siam; Hotaling, James M; Craig, James R; Myers, Jeremy B; Brant, William O

2017-10-01

To examine the rationale and applications of amniotic tissue augmentation in urological surgery. Published literature in English-language was reviewed for basic science and clinical use of amniotic or amnion-chorionic tissue in genitourinary tissues. Basic science and animal studies support the likely benefit of clinical applications of amnion-derived tissues in a variety of urologic interventions. The broad number of properties found in amniotic membrane, coupled with its immunologically privileged status presents a number of future applications in the urological surgical realm. These applications are in their clinical infancy and suggest that further studies are warranted to investigate the use of these products in a systematic fashion.

An Evaluation of the Limited Contract Warrant Experiment at March AFB.

DTIC Science & Technology

1986-09-01

as booking entertainment, and contracting for food and beverages . (66:12) The only time a contracting officer was consulted was when the purchase...34-, , • % . , •, ", ’,. .. . - - "."- .- - ,- -~. .-.• - . *- *** -.- -, ~ -, v -,- .,- • ,.-, .- ,- % S% j%’..’ ,..p S-. AFIT/GLM/LSM/86S-70 AN EVALUATION OF THE LIMITED CONTRACT WARRANT EXPERIMENT AT MARCH AFB THESIS... v List of Abbreviations ........................................................... vi :% Abstract

21 CFR 1316.12 - Refusal to allow inspection with an administrative warrant.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Refusal to allow inspection with an administrative warrant. 1316.12 Section 1316.12 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE ADMINISTRATIVE FUNCTIONS, PRACTICES, AND PROCEDURES Administrative Inspections § 1316.12 Refusal to allow...

Right-­turn traffic volume adjustment in traffic signal warrant analysis : final report.

DOT National Transportation Integrated Search

2016-05-06

This report was based on the research project, Right-Turn Traffic Volume Adjustment in Traffic Signal Warrants, sponsored by the Nevada Department of Transportation (NDOT) and SOLARIS. Right-turn traffic does not affect intersection performance in th...

Unveiling correlations between financial variables and topological metrics of trading networks: Evidence from a stock and its warrant

NASA Astrophysics Data System (ADS)

Li, Ming-Xia; Jiang, Zhi-Qiang; Xie, Wen-Jie; Xiong, Xiong; Zhang, Wei; Zhou, Wei-Xing

2015-02-01

Traders develop and adopt different trading strategies attempting to maximize their profits in financial markets. These trading strategies not only result in specific topological structures in trading networks, which connect the traders with the pairwise buy-sell relationships, but also have potential impacts on market dynamics. Here, we present a detailed analysis on how the market behaviors are correlated with the structures of traders in trading networks based on audit trail data for the Baosteel stock and its warrant at the transaction level from 22 August 2005 to 23 August 2006. In our investigation, we divide each trade day into 48 rolling time windows with a length of 5 min, construct a trading network within each window, and obtain a time series of over 11,600 trading networks. We find that there are strongly simultaneous correlations between the topological metrics (including network centralization, assortative index, and average path length) of trading networks that characterize the patterns of order execution and the financial variables (including return, volatility, intertrade duration, and trading volume) for the stock and its warrant. Our analysis may shed new lights on how the microscopic interactions between elements within complex system affect the system's performance.

Defense Health Care: Evaluation of TRICARE Pharmacy Services Contract Structure is Warranted

DTIC Science & Technology

2013-09-01

involves providing coordinated health care interventions and communications to patients who have chronic conditions, such as diabetes or asthma ...DEFENSE HEALTH CARE Evaluation of TRICARE Pharmacy Services Contract Structure Is Warranted Report to the...COVERED 00-00-2013 to 00-00-2013 4. TITLE AND SUBTITLE Defense Health Care : Evaluation of TRICARE Pharmacy Services Contract Structure Is

A review on Black-Scholes model in pricing warrants in Bursa Malaysia

NASA Astrophysics Data System (ADS)

Gunawan, Nur Izzaty Ilmiah Indra; Ibrahim, Siti Nur Iqmal; Rahim, Norhuda Abdul

2017-01-01

This paper studies the accuracy of the Black-Scholes (BS) model and the dilution-adjusted Black-Scholes (DABS) model to pricing some warrants traded in the Malaysian market. Mean Absolute Error (MAE) and Mean Absolute Percentage Error (MAPE) are used to compare the two models. Results show that the DABS model is more accurate than the BS model for the selected data.

Right-\\0xADturn traffic volume adjustment in traffic signal warrant analysis : final report.

DOT National Transportation Integrated Search

2016-05-06

This report was based on the research project, Right-Turn Traffic Volume Adjustment in : Traffic Signal Warrants, sponsored by the Nevada Department of Transportation (NDOT) : and SOLARIS. Right-turn traffic does not affect intersection performance i...

Moisture fluxes towards Switzerland: investigating future changes in CMIP5 climate models

NASA Astrophysics Data System (ADS)

Fazan, Valerie; Martius, Olivia; Martynov, Andrey; Panziera, Luca

2017-04-01

High integrated vapor transport (IVT) in the atmosphere directed perpendicular to the orography is an important proxy for flood related precipitation in many mountainous areas around the world. Here we focus on flood related IVT and its changes in a warmer climate in Switzerland, where most high-impact floods events in the past 30 years were connected to exceptional IVT upstream of the mountains. Our study aims at investigating how these critical IVT values are projected to evolve in the future in a changing climate. The IVT is computed from 15 CMIP5 climate models for the past (1950-2005) and the future (2006-2100) under the RCP 8.5 scenario ("business as usual"). In order to check the accuracy of the models and the effect of the varying resolution, present day IVT from the CMIP5 models is compared with the ERA-Interim reanalysis data (period 1979-2015). A quantile mapping technique is then used to correct biases. The same bias corrections are applied to the future (2006-2100) IVT data. Finally, future changes in extreme IVT are investigated. This includes an analysis of changes in the magnitude and direction of the moisture flux in the different seasons for different regions in Switzerland.

Is Bringing Back Warrant Officers the Answer A Loot at How They Could Work in the Air Force Cyber Operations Career Field

DTIC Science & Technology

2017-03-16

warrant officers in the Navy, they did lead directly to their place being cemented firmly in the Navy’s rank structure. The Navy exclusively...Dennis Steele , “The U.S. Army Warrant Officer Corps: Still a Work in Progress,” Army 62 no. 7 (July 2012), 40. 65. Department of the Army, The Army...force- cyber-secure.aspx. Steele , Dennis. “The U.S. Army Warrant Officer Corps: Still a Work in Progress.” Army 62 no. 7 (July 2012): 39-41

The Recruitment and Retention of the 180A: The Special Forces Warrant Officer

DTIC Science & Technology

2015-03-01

that are gained through unique institutions associated with the vocation itself. The professional individual is an expert who performs a service that...Warrant Officer. Research Report 1851. U.S. Army Research Institute . Glaser, B., & Strauss, A. (1967). The discovery of grounded theory : Strategies...the Special Forces Regiment. The watrant officer’s institutional knowledge--developed over years of operational experience-is essential to the success

A Delphi Investigation into Future Trends in E-Learning in Israel

ERIC Educational Resources Information Center

Aharony, Noa; Bronstein, Jenny

2014-01-01

The purpose of this study is to investigate the views and opinions of e-learning experts regarding future trends in the e-learning arena. The Delphi technique was chosen as a method of study. This technique is an efficient and effective group communication process designed to systematically elicit judgments from experts in their selected area of…

41 CFR 302-6.105 - What is a “compelling reason” warranting extension of my authorized period for claiming an actual...

Code of Federal Regulations, 2014 CFR

2014-07-01

... reasonâ warranting extension of my authorized period for claiming an actual TQSE reimbursement? 302-6.105... is a “compelling reason” warranting extension of my authorized period for claiming an actual TQSE... problems (e.g., delay in settlement on the new residence, or short-term delay in construction of the...

41 CFR 302-6.105 - What is a “compelling reason” warranting extension of my authorized period for claiming an actual...

Code of Federal Regulations, 2013 CFR

2013-07-01

... reasonâ warranting extension of my authorized period for claiming an actual TQSE reimbursement? 302-6.105... is a “compelling reason” warranting extension of my authorized period for claiming an actual TQSE... problems (e.g., delay in settlement on the new residence, or short-term delay in construction of the...

41 CFR 302-6.105 - What is a “compelling reason” warranting extension of my authorized period for claiming an actual...

Code of Federal Regulations, 2011 CFR

2011-07-01

... reasonâ warranting extension of my authorized period for claiming an actual TQSE reimbursement? 302-6.105... is a “compelling reason” warranting extension of my authorized period for claiming an actual TQSE... problems (e.g., delay in settlement on the new residence, or short-term delay in construction of the...

41 CFR 302-6.105 - What is a “compelling reason” warranting extension of my authorized period for claiming an actual...

Code of Federal Regulations, 2010 CFR

2010-07-01

... reasonâ warranting extension of my authorized period for claiming an actual TQSE reimbursement? 302-6.105... is a “compelling reason” warranting extension of my authorized period for claiming an actual TQSE... problems (e.g., delay in settlement on the new residence, or short-term delay in construction of the...

"Warrant" Revisited: Integrating Mathematics Teachers' Pedagogical and Epistemological Considerations into Toulmin's Model for Argumentation

ERIC Educational Resources Information Center

Nardi, Elena; Biza, Irene; Zachariades, Theodossios

2012-01-01

In this paper, we propose an approach to analysing teacher arguments that takes into account field dependence--namely, in Toulmin's sense, the dependence of warrants deployed in an argument on the field of activity to which the argument relates. Freeman, to circumvent issues that emerge when we attempt to determine the field(s) that an argument…

12 CFR 269b.240 - The investigation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... face, no investigation shall be required except to determine whether or not attending circumstances warrant waiving the time requirements, set forth in § 269b.110. The investigator may request the...

Diagnosing true virtue? Remote scenarios, warranted virtue attributions, and virtuous medical practice.

PubMed

Oakley, Justin

2016-02-01

Immanuel Kant argues in the Foundations that remote scenarios are diagnostic of genuine virtue. When agents commonly thought to have a particular virtue fail to exhibit that virtue in an extreme situation, he argues, they do not truly have the virtue at all, and our propensities to fail in such ways indicate that true virtue might never have existed. Kant's suggestion that failure to show, say, courage in extraordinary circumstances necessarily silences one's claim to have genuine courage seems to rely on an implausibly demanding standard for warranted virtue attributions. In contrast to this approach, some philosophers-such as Robert Adams and John Doris-have argued for probabilistic accounts of warranted virtue attributions. But despite the initial plausibility of such accounts, I argue that a sole reliance on probabilistic approaches is inadequate, as they are insufficiently sensitive to considerations of credit and fault, which emerge when agents have developed various insurance strategies and protective capacities against their responding poorly to particular eventualities. I also argue that medical graduates should develop the sorts of virtuous dispositions necessary to protect patient welfare against various countervailing influences (even where such influences might be encountered only rarely), and that repeated failures to uphold the proper goals of medicine in emergency scenarios might indeed be diagnostic of whether an individual practitioner does have the relevant medical virtue. In closing, I consider the dispositions involved in friendship. I seek to develop a principled way of determining when remote scenarios can be illuminating of genuine friendship and genuine virtue.

Visionary leadership and the future of VA health system.

PubMed

Bezold, C; Mayer, E; Dighe, A

1997-01-01

As the U.S. Department of Veterans Affairs (VA) makes the change over to Veterans Integrated Service Network (VISNs) the need for new and better leadership is warranted if VA wants to not only survive, but thrive in the emerging twenty-first century healthcare system. VA can prepare for the future and meet the challenges facing them by adopting a system of visionary leadership. The use of scenarios and vision techniques are explained as they relate to VA's efforts to move toward their new system of VISNs. The four scenarios provide snapshots of possible futures for the U.S. healthcare system as well as the possible future role and mission of VA--from VA disappearing to its becoming a premier virtual organization.

Nonadditive entropies yield probability distributions with biases not warranted by the data.

PubMed

Pressé, Steve; Ghosh, Kingshuk; Lee, Julian; Dill, Ken A

2013-11-01

Different quantities that go by the name of entropy are used in variational principles to infer probability distributions from limited data. Shore and Johnson showed that maximizing the Boltzmann-Gibbs form of the entropy ensures that probability distributions inferred satisfy the multiplication rule of probability for independent events in the absence of data coupling such events. Other types of entropies that violate the Shore and Johnson axioms, including nonadditive entropies such as the Tsallis entropy, violate this basic consistency requirement. Here we use the axiomatic framework of Shore and Johnson to show how such nonadditive entropy functions generate biases in probability distributions that are not warranted by the underlying data.

20 CFR 416.934 - Impairments which may warrant a finding of presumptive disability or presumptive blindness.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Impairments which may warrant a finding of presumptive disability or presumptive blindness. 416.934 Section 416.934 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Presumptive Disability and...

Core-shell chromium silicide-silicon nanopillars: a contact material for future nanosystems.

PubMed

Chang, Mu-Tung; Chen, Chih-Yen; Chou, Li-Jen; Chen, Lih-Juann

2009-11-24

Chromium silicide nanostructures are fabricated inside silicon nanopillars grown by the vapor-liquid-solid mechanism. The remarkable field-emission behavior of these nanostructures results from extensive improvement of carrier transport due to the reduced energy barrier between the metal and semiconductor layers. The results warrant consideration of chromium silicide as a potentially important contact material in future nanosystems.

24 CFR 4.32 - Investigation by Office of Inspector General.

Code of Federal Regulations, 2010 CFR

2010-04-01

... conduct the investigation and upon completion issue a report of the investigation to the Ethics Law... investigation is not warranted, it shall notify the Ethics Law Division of that determination. If, after a...

Future Time Orientation and Student Expectations: An Empirical Investigation

ERIC Educational Resources Information Center

Amyx, Douglas; Bristow, Dennis

2004-01-01

Navajo and Anglo college students' time orientation scores from the Future Time Orientation (FTO) Scale (Bristol & Amyx, 1996) were analyzed and compared. Anglo students were found to be significantly more future time oriented in two of the three dimensions: temporal distance and involvement with time. Future time orientation was used to explain…

Preparing Science Teachers for the future

NASA Astrophysics Data System (ADS)

Stein, Fredrick

2002-04-01

What will teachers need in the future to be successful? What will "successful" mean in the future? Are the teaching approaches learned 40 years ago still relevant for tomorrow's classrooms? Will technology really change the way physics is taught (K-16)? Will we close the performance gap between students of differing ethnicity? Are schools of education rising to the challenge to answer these questions? Can college and university physics departments rise to the challenge of presenting physics to all students in an engaging manner? What can the APS, in partnership with AAPT and AIP, do to find the answers and provide strategies to improve the science preparation of future teachers? PhysTEC aims to help physics and education faculty work together to provide an education for future teachers that emphasizes a student-centered, hands-on, inquiry-based approach to learning science. The compelling evidence produced from Physics Education Research warrants this approach. A National Science Foundation grant of 5.76 million and a 498 thousand grant from the Fund for the Improvement of Postsecondary Education support PhysTEC, its partners and activities. http://www.phystec.org/

An fMRI investigation of the relationship between future imagination and cognitive flexibility

PubMed Central

Roberts, R.P.; Wiebels, K.; Sumner, R.L.; van Mulukom, V.; Grady, C.L.; Schacter, D.L.; Addis, D.R.

2016-01-01

While future imagination is largely considered to be a cognitive process grounded in default mode network activity, studies have shown that future imagination recruits regions in both default mode and frontoparietal control networks. In addition, it has recently been shown that the ability to imagine the future is associated with cognitive flexibility, and that tasks requiring cognitive flexibility result in increased coupling of the default mode network with frontoparietal control and salience networks. In the current study, we investigated the neural correlates underlying the association between cognitive flexibility and future imagination in two ways. First, we experimentally varied the degree of cognitive flexibility required during future imagination by manipulating the disparateness of episodic details contributing to imagined events. To this end, participants generated episodic details (persons, locations, objects) within three social spheres; during fMRI scanning they were presented with sets of three episodic details all taken from the same social sphere (Congruent condition) or different social spheres (Incongruent condition) and required to imagine a future event involving the three details. We predicted that, relative to the Congruent condition, future simulation in the Incongruent condition would be associated with increased activity in regions of the default mode, frontoparietal and salience networks. Second, we hypothesized that individual differences in cognitive flexibility, as measured by performance on the Alternate Uses Task, would correspond to individual differences in the brain regions recruited during future imagination. A task partial least squares (PLS) analysis showed that the Incongruent condition resulted in an increase in activity in regions in salience networks (e.g. the insula) but, contrary to our prediction, reduced activity in many regions of the default mode network (including the hippocampus). A subsequent functional

40 CFR 14.8 - Investigation of claims.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Investigation of claims. 14.8 Section 14.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL EMPLOYEE PERSONAL PROPERTY... and receipts), interview witnesses, and conduct any further investigation he believes is warranted by...

Additional Technologies and Investigations for Provision of Future Aeronautical Communications

NASA Technical Reports Server (NTRS)

Gilbert, Tricia; Jin, Jenny; Berger, Jason; Henriksen, Steve

2008-01-01

The following NASA Contractor Report documents the in-depth studies on select technologies that could support long-term aeronautical mobile communications operating concepts. This work was performed during the third and final phase of NASA s Technology Assessment for the Federal Aviation Administration (FAA)/EUROCONTROL Future Communications Study (FCS) under a multiyear NASA contract. It includes the associated findings of ITT Corporation and NASA Glenn Research Center to the FAA as of the end of May 2007. The activities documented in this report focus on three final technology candidates identified by the United States, and were completed before sufficient information about two additional technology candidates proposed by EUROCONTROL was made available. A separate report to be published by NASA/CR-2008-215144, entitled Final Report on Technology Investigations for Provision of Future Aeronautical Communications will include an assessment of all five final candidate technologies considered by the U.S. agencies (FAA and NASA) and EUROCONTROL. It will also provide an overview of the entire technology assessment process, including final recommendations. All three phases of this work were performed in compliance with the Terms of Reference for the Action Plan number 17 (AP-17) cooperative research agreement among EUROCONTROL, FAA, and NASA along with the general guidance of the FAA and EUROCONTROL available throughout this study.

Is excision biopsy of fibroadenomas based solely on size criteria warranted?

PubMed

Neville, Grace; Neill, Cathleen O'; Murphy, Rosemary; Corrigan, Mark; Redmond, Paul H; Feeley, Linda; Bennett, Michael W; O'Connell, Fionnuala; Browne, Tara Jane

2018-05-25

Fibroadenomas (FA) are the most common benign tumor in the female breast. Most are managed conservatively provided there is clinical, radiologic, and pathologic concordance. However, surgical excision is typically recommended for cellular fibroepithelial lesions or those lesions with clinical, radiologic, or pathologic features concerning for phyllodes tumor (PT). Some studies have suggested surgical excision in all FA >30 mm to reduce core needle biopsy (CNB) sampling errors. The aim of our study was to evaluate, in the absence of any other concerning clinicopathologic features, whether surgical excision of FA was warranted based on size criteria alone. Cork University Hospital is a large academic center in Southern Ireland. Its breast cancer center provides both a screening and symptomatic service and diagnoses approximately 600 cancers per year. The breast histopathological data base was reviewed for all CNBs from January 1, 2010, to June 30, 2015, with a diagnosis of FA that went on to have excision at our institution. We excluded all cellular fibroepithelial lesions and those cases with co-existent lobular neoplasia, ductal carcinoma in situ, invasive carcinoma, atypical ductal hyperplasia, or lesions which would require excision in their own right. Cases in which the radiologic targeted mass was discordant with a diagnosis of FA were also excluded. Patient demographics and preoperative radiologic size and the radiologic target were recorded in each case. All radiology was reviewed by a breast radiologist prior to inclusion in the study, and there was histologic radiologic concordance with a diagnosis of FA in all cases. A total of 12,109 consecutive radiologically guided CNB were performed January 2010-June 2015; 3438 with a diagnosis of FA were identified of which 290 cases went on to have surgical excision. Of those 290 cases; 98.28% (n = 285) were confirmed as FA on excision. The remaining 1.72% (n = 5) had atypical features-FA with LCIS (n = 1

24 CFR 6.11 - Conduct of investigations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Responsible Official, or his or her designee, will assess the complaint for acceptance, rejection, or referral... be expanded where facts or allegations warrant further investigation. (3) Early compliance resolution...

24 CFR 6.11 - Conduct of investigations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Responsible Official, or his or her designee, will assess the complaint for acceptance, rejection, or referral... be expanded where facts or allegations warrant further investigation. (3) Early compliance resolution...

Future directions of multiple behavior change research.

PubMed

Geller, Karly; Lippke, Sonia; Nigg, Claudio R

2017-02-01

Non-communicable diseases (i.e., chronic diseases including cardiovascular disease, cancer, chronic respiratory disease, diabetes and obesity) result in 36 million deaths each year. Individuals' habitual participation in a single health-risk behaviors substantially contribute to morbidity and mortality (e.g., tobacco use, daily fast food intake, etc.); however, more concerning is the impact of typically co-occurring or clustering of multiple health-risk behaviors. This burden can be minimized through successful cessation of health-risk behaviors and adoption of healthy behaviors; namely healthy lifestyle adoption or multiple health behavior change (MHBC). MHBC is a developing field and future research recommendations are provided to advance MHBC research. A valid measure of MHBC (i.e., lifestyle) is warranted to provide the needed basis for MHBC investigations and evaluations. MHBC is thought to occur through shared co-variation of underlying motivating mechanisms, but how these relationships influence behavior remains unclear. A better understanding of the relationship between behaviors and the related motivating mechanisms (and potential cross-relationship of influences) is needed. Future research should also aim to improve lifestyles through understanding how to change multiple health behaviors. Finally, MHBC research should target the development of sustainable interventions which result in lasting effects (e.g., capacity, systems, policy and environmental changes), with dissemination considered during development. Focusing MHBC research in these areas will increase our understanding and maximize the impact on the health of populations.

Future distribution of tundra refugia in northern Alaska

USGS Publications Warehouse

Hope, Andrew G.; Waltari, Eric; Payer, David C.; Cook, Joseph A.; Talbot, Sandra L.

2013-01-01

Climate change in the Arctic is a growing concern for natural resource conservation and management as a result of accelerated warming and associated shifts in the distribution and abundance of northern species. We introduce a predictive framework for assessing the future extent of Arctic tundra and boreal biomes in northern Alaska. We use geo-referenced museum specimens to predict the velocity of distributional change into the next century and compare predicted tundra refugial areas with current land-use. The reliability of predicted distributions, including differences between fundamental and realized niches, for two groups of species is strengthened by fossils and genetic signatures of demographic shifts. Evolutionary responses to environmental change through the late Quaternary are generally consistent with past distribution models. Predicted future refugia overlap managed areas and indicate potential hotspots for tundra diversity. To effectively assess future refugia, variable responses among closely related species to climate change warrants careful consideration of both evolutionary and ecological histories.

Placing the pieces: Reconstructing the original property mosaic in a warrant and patent watershed

USGS Publications Warehouse

Bain, D.J.; Brush, G.S.

2005-01-01

Recent research shows that land use history is an important determinant of current ecosystem function. In the United States, characterization of land use change following European settlement requires reconstruction of the original property mosaic. However, this task is difficult in unsystematically surveyed areas east of the Appalachian Mountains. The Gwynns Falls watershed (Baltimore, MD) was originally surveyed in the 1600-1700s under a system of warrants and patents (commonly known as 'metes and bounds'). A method for the reconstruction and mapping of warrant and patent properties is presented and used to map the original property mosaic in the Gwynns Falls watershed. Using the mapped mosaic, the persistence of properties and property lines in the current Gwynns Falls landscape is considered. The results of this research indicate that as in agricultural areas, the original property lines in the Gwynns Falls watershed are persistent. At the same time, the results suggest that the property mosaic in heavily urbanized/suburbanized areas is generally 'reset.' Further, trends in surveying technique, parcel size, and settlement patterns cause property line density and property shape complexity to increase in the less urbanized upper watershed. The persistence of original patterns may be damping expression of heterogeneity gradients in this urban landscape. This spatial pattern of complexity in the original mosaic is directly opposite of hypothesized patterns of landscape heterogeneity arising from urbanization. The technique reported here and the resulting observations are important for landscape pattern studies in areas settled under unsystematic survey systems, especially the heavily urbanized areas of the eastern United States. ?? 2004 Kluwer Academic Publishers.

Dust particles investigation for future Russian lunar missions.

NASA Astrophysics Data System (ADS)

Dolnikov, Gennady; Horanyi, Mihaly; Esposito, Francesca; Zakharov, Alexander; Popel, Sergey; Afonin, Valeri; Borisov, Nikolay; Seran, Elena; Godefroy, Michel; Shashkova, Inna; Kuznetsov, Ilya; Lyash, Andrey; Vorobyova, Elena; Petrov, Oleg; Lisin, Evgeny

One of the complicating factors of the future robotic and human lunar landing missions is the influence of the dust. Meteorites bombardment has accompanied by shock-explosive phenomena, disintegration and mix of the lunar soil in depth and on area simultaneously. As a consequence, the lunar soil has undergone melting, physical and chemical transformations. Recently we have the some reemergence for interest of Moon investigation. The prospects in current century declare USA, China, India, and European Union. In Russia also prepare two missions: Luna-Glob and Luna-Resource. Not last part of investigation of Moon surface is reviewing the dust condition near the ground of landers. Studying the properties of lunar dust is important both for scientific purposes to investigation the lunar exosphere component and for the technical safety of lunar robotic and manned missions. The absence of an atmosphere on the Moon's surface is leading to greater compaction and sintering. Properties of regolith and dust particles (density, temperature, composition, etc.) as well as near-surface lunar exosphere depend on solar activity, lunar local time and position of the Moon relative to the Earth's magneto tail. Upper layers of regolith are an insulator, which is charging as a result of solar UV radiation and the constant bombardment of charged particles, creates a charge distribution on the surface of the moon: positive on the illuminated side and negative on the night side. Charge distribution depends on the local lunar time, latitude and the electrical properties of the regolith (the presence of water in the regolith can influence the local distribution of charge). On light side of Moon near surface layer there exists possibility formation dusty plasma system. Altitude of levitation is depending from size of dust particle and Moon latitude. The distribution dust particle by size and altitude has estimated with taking into account photoelectrons, electrons and ions of solar wind, solar

Investigation of beam self-polarization in the future e+e- circular collider

NASA Astrophysics Data System (ADS)

Gianfelice-Wendt, E.

2016-10-01

The use of resonant depolarization has been suggested for precise beam energy measurements (better than 100 keV) in the e+e- Future Circular Collider (FCC-e+e-) for Z and W W physics at 45 and 80 GeV beam energy respectively. Longitudinal beam polarization would benefit the Z peak physics program; however it is not essential and therefore it will be not investigated here. In this paper the possibility of self-polarized leptons is considered. Preliminary results of simulations in presence of quadrupole misalignments and beam position monitors (BPMs) errors for a simplified FCC-e+e- ring are presented.

Is a comparative clinical trial for breast cancer tumor markers to monitor disease recurrence warranted? A value of information analysis

PubMed Central

Thariani, Rahber; Henry, Norah Lynn; Ramsey, Scott D; Blough, David K; Barlow, Bill; Gralow, Julie R; Veenstra, David L

2014-01-01

Background Breast cancer tumor markers are used by some clinicians to screen for disease recurrence risk. Since there is limited evidence of benefit, additional research may be warranted. Aim To assess the potential value of a randomized clinical trial of breast tumor marker testing in routine follow-up of high-risk, stage II–III breast cancer survivors. Materials & methods We developed a decision-analytic model of tumor marker testing plus standard surveillance every 3–6 months for 5 years. The expected value of sample information was calculated using probabilistic simulations and was a function of: the probability of selecting the optimal monitoring strategy with current versus future information; the impact of choosing the nonoptimal strategy; and the size of the population affected. Results The value of information for a randomized clinical trial involving 9000 women was US$214 million compared with a cost of US$30–60 million to conduct such a trial. The probability of making an alternate, nonoptimal decision and choosing testing versus no testing was 32% with current versus future information from the trial. The impact of a nonoptimal decision was US$2150 and size of population impacted over 10 years was 308,000. The value of improved information on overall survival was US$105 million, quality of life US$37 million and test performance US$71 million. Conclusion Conducting a randomized clinical trial of breast cancer tumor markers appears to offer a good societal return on investment. Retrospective analyses to assess test performance and evaluation of patient quality of life using tumor markers may also offer valuable areas of research. However, alternative investments may offer even better returns in investments and, as such, the trial concept deserves further study as part of an overall research-portfolio evaluation. PMID:24236631

Vegetation-mediated Climate Impacts on Historical and Future Ozone Air Quality

NASA Astrophysics Data System (ADS)

Tai, A. P. K.; Fu, Y.; Mickley, L. J.; Heald, C. L.; Wu, S.

2014-12-01

Changes in climate, natural vegetation and human land use are expected to significantly influence air quality in the coming century. These changes and their interactions have important ramifications for the effectiveness of air pollution control strategies. In a series of studies, we use a one-way coupled modeling framework (GEOS-Chem driven by different combinations of historical and future meteorological, land cover and emission data) to investigate the effects of climate-vegetation changes on global and East Asian ozone air quality from 30 years ago to 40 years into the future. We find that future climate and climate-driven vegetation changes combine to increase summertime ozone by 2-6 ppbv in populous regions of the US, Europe, East Asia and South Asia by year 2050, but including the interaction between CO2 and biogenic isoprene emission reduces the climate impacts by more than half. Land use change such as cropland expansion has the potential to either mostly offset the climate-driven ozone increases (e.g., in the US and Europe), or greatly increase ozone (e.g., in Southeast Asia). The projected climate-vegetation effects in East Asia are particularly uncertain, reflecting a less understood ozone production regime. We thus further study how East Asian ozone air quality has evolved since the early 1980s in response to climate, vegetation and emission changes to shed light on its likely future course. We find that warming alone has led to a substantial increase in summertime ozone in populous regions by 1-4 ppbv. Despite significant cropland expansion and urbanization, increased summertime leafiness of vegetation in response to warming and CO2 fertilization has reduced ozone by 1-2 ppbv, driven by enhanced ozone deposition dominating over elevated biogenic emission and partially offsetting the warming effect. The historical role of CO2-isoprene interaction in East Asia, however, remains highly uncertain. Our findings demonstrate the important roles of land cover

Future lunar missions and investigation of dusty plasma processes on the Moon

NASA Astrophysics Data System (ADS)

Popel, Sergey I.; Zelenyi, Lev M.; Zelenyi

2013-08-01

From the Apollo era of exploration, it was discovered that sunlight was scattered at the terminators giving rise to ``horizon glow'' and ``streamers'' above the lunar surface. Subsequent investigations have shown that the sunlight was most likely scattered by electrostatically charged dust grains originating from the surface. A renaissance is being observed currently in investigations of the Moon. The Luna-Glob and Luna-Resource missions (the latter jointly with India) are being prepared in Russia. Some of these missions will include investigations of lunar dust. Here we discuss the future experimental investigations of lunar dust within the missions of Luna-Glob and Luna-Resource. We consider the dusty plasma system over the lunar surface and determine the maximum height of dust rise. We describe mechanisms of formation of the dusty plasma system over the Moon and its main properties, determine distributions of electrons and dust over the lunar surface, and show a possibility of rising dust particles over the surface of the illuminated part of the Moon in the entire range of lunar latitudes. Finally, we discuss the effect of condensation of micrometeoriod substance during the expansion of the impact plume and show that this effect is important from the viewpoint of explanation of dust particle rise to high altitudes in addition to the dusty plasma effects.

Investigation of beam self-polarization in the future e + e - circular collider

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gianfelice-Wendt, E.

The use of resonant depolarization has been suggested for precise beam energy measurements (better than 100 keV) in the e +e - Future Circular Collider (FCC-e +e -) for Z and WW physics at 45 and 80 GeV beam energy respectively. Longitudinal beam polarization would benefit the Z peak physics program; however it is not essential and therefore it will be not investigated here. In this paper the possibility of self-polarized leptons is considered. As a result, preliminary results of simulations in presence of quadrupole misalignments and beam position monitors (BPMs) errors for a simplified FCC-e +e - ring are presented.

Investigation of beam self-polarization in the future e + e - circular collider

DOE PAGES

Gianfelice-Wendt, E.

2016-10-24

The use of resonant depolarization has been suggested for precise beam energy measurements (better than 100 keV) in the e +e - Future Circular Collider (FCC-e +e -) for Z and WW physics at 45 and 80 GeV beam energy respectively. Longitudinal beam polarization would benefit the Z peak physics program; however it is not essential and therefore it will be not investigated here. In this paper the possibility of self-polarized leptons is considered. As a result, preliminary results of simulations in presence of quadrupole misalignments and beam position monitors (BPMs) errors for a simplified FCC-e +e - ring are presented.

Fit between Future Thinking and Future Orientation on Creative Imagination

ERIC Educational Resources Information Center

Chiu, Fa-Chung

2012-01-01

The purpose of the current study is to investigate the impact of future thinking, and the fit between future thinking and future orientation on creative thinking. In Study 1, 83 undergraduates were randomly assigned to three groups: 50-year future thinking, 5-year future thinking, and the present-day thinking. First, the priming tasks, in which…

12 CFR 7.1006 - Loan agreement providing for a share in profits, income, or earnings or for stock warrants.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Loan agreement providing for a share in profits, income, or earnings or for stock warrants. 7.1006 Section 7.1006 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Bank Powers § 7.1006 Loan agreement...

12 CFR 7.1006 - Loan agreement providing for a share in profits, income, or earnings or for stock warrants.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Loan agreement providing for a share in profits, income, or earnings or for stock warrants. 7.1006 Section 7.1006 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Bank Powers § 7.1006 Loan agreement...

A pilot investigation to optimise methods for a future satiety preload study.

PubMed

Hobden, Mark R; Guérin-Deremaux, Laetitia; Commane, Daniel M; Rowland, Ian; Gibson, Glenn R; Kennedy, Orla B

2017-01-01

Preload studies are used to investigate the satiating effects of foods and food ingredients. However, the design of preload studies is complex, with many methodological considerations influencing appetite responses. The aim of this pilot investigation was to determine acceptability, and optimise methods, for a future satiety preload study. Specifically, we investigated the effects of altering (i) energy intake at a standardised breakfast (gender-specific or non-gender specific), and (ii) the duration between mid-morning preload and ad libitum lunch meal, on morning appetite scores and energy intake at lunch. Participants attended a single study visit. Female participants consumed a 214-kcal breakfast ( n  = 10) or 266-kcal breakfast ( n  = 10), equivalent to 10% of recommended daily energy intakes for females and males, respectively. Male participants ( n  = 20) consumed a 266-kcal breakfast. All participants received a 250-ml orange juice preload 2 h after breakfast. The impact of different study timings was evaluated in male participants, with 10 males following one protocol (protocol 1) and 10 males following another (protocol 2). The duration between preload and ad libitum lunch meal was 2 h (protocol 1) or 2.5 h (protocol 2), with the ad libitum lunch meal provided at 12.00 or 13.00, respectively. All female participants followed protocol 2. Visual analogue scale (VAS) questionnaires were used to assess appetite responses and food/drink palatability. Correlation between male and female appetite scores was higher with the provision of a gender-specific breakfast, compared to non-gender-specific breakfast (Pearson correlation of 0.747 and 0.479, respectively). No differences in subjective appetite or ad libitum energy intake were found between protocols 1 and 2. VAS mean ratings of liking, enjoyment, and palatability were all > 66 out of 100 mm for breakfast, preload, and lunch meals. The findings of this pilot study confirm the acceptability

Investigating Allegations of Inappropriate Physical Punishment of Students by School Employees.

ERIC Educational Resources Information Center

Pearce, Alexis C.

1992-01-01

Any complaint against a school employee regarding inappropriate physical punishment should be taken seriously by administrators and pursued vigorously by an investigating attorney. The standards (especially regarding probable cause and obtaining warrants) for investigating such allegations are less stringent than those imposed in criminal…

Advanced Choice Employment (ACE) factors influencing PGY-1 workplace selection and future career intentions of a cohort of doctors in Waikato.

PubMed

Clark, Helen; de Beer, Wayne; Gibbons, Veronique

2017-01-27

To assess whether or not a sample of PGY-1 doctors in the Waikato region remained satisfied with the ACE system for employment 12 years after its inception. An anonymous paper-based survey was completed by a cohort (n=60) of 2015 and 2016 PGY-1 doctors based at the Waikato DHB. Questions were based around reasons for selecting the DHB, satisfaction with the ACE process and future career intentions. Overall satisfaction with the ACE selection process was reasonable (63%). Over 60% of the 2015 and 2016 cohorts chose Waikato as their first choice DHB, and of those, over 90% intended to carry on through to at least PGY2 level at the DHB. An overwhelming majority (93-96%) intended to continue practicing in New Zealand. Consistent trends were observed across the two cohorts in regards to their reasons for selecting the DHB, satisfaction with ACE and future intentions, with some differences observed with familial background and interest in pursuing hospital-based specialties. Our findings suggest that ACE remains a satisfactory recruiting system for postgraduate junior doctors, however, motives around initial DHB selection and future vocational intentions remain unclear and warrant further investigation.

Future Tense and Economic Decisions: Controlling for Cultural Evolution

PubMed Central

Roberts, Seán G.; Winters, James; Chen, Keith

2015-01-01

A previous study by Chen demonstrates a correlation between languages that grammatically mark future events and their speakers' propensity to save, even after controlling for numerous economic and demographic factors. The implication is that languages which grammatically distinguish the present and the future may bias their speakers to distinguish them psychologically, leading to less future-oriented decision making. However, Chen's original analysis assumed languages are independent. This neglects the fact that languages are related, causing correlations to appear stronger than is warranted (Galton's problem). In this paper, we test the robustness of Chen's correlations to corrections for the geographic and historical relatedness of languages. While the question seems simple, the answer is complex. In general, the statistical correlation between the two variables is weaker when controlling for relatedness. When applying the strictest tests for relatedness, and when data is not aggregated across individuals, the correlation is not significant. However, the correlation did remain reasonably robust under a number of tests. We argue that any claims of synchronic patterns between cultural variables should be tested for spurious correlations, with the kinds of approaches used in this paper. However, experiments or case-studies would be more fruitful avenues for future research on this specific topic, rather than further large-scale cross-cultural correlational studies. PMID:26186527

Future Tense and Economic Decisions: Controlling for Cultural Evolution.

PubMed

Roberts, Seán G; Winters, James; Chen, Keith

2015-01-01

A previous study by Chen demonstrates a correlation between languages that grammatically mark future events and their speakers' propensity to save, even after controlling for numerous economic and demographic factors. The implication is that languages which grammatically distinguish the present and the future may bias their speakers to distinguish them psychologically, leading to less future-oriented decision making. However, Chen's original analysis assumed languages are independent. This neglects the fact that languages are related, causing correlations to appear stronger than is warranted (Galton's problem). In this paper, we test the robustness of Chen's correlations to corrections for the geographic and historical relatedness of languages. While the question seems simple, the answer is complex. In general, the statistical correlation between the two variables is weaker when controlling for relatedness. When applying the strictest tests for relatedness, and when data is not aggregated across individuals, the correlation is not significant. However, the correlation did remain reasonably robust under a number of tests. We argue that any claims of synchronic patterns between cultural variables should be tested for spurious correlations, with the kinds of approaches used in this paper. However, experiments or case-studies would be more fruitful avenues for future research on this specific topic, rather than further large-scale cross-cultural correlational studies.

41 CFR 302-9.171 - If circumstances warrant an authorization to transport a POV to my post of duty after my...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES... Transportation Subsequent to the Time of Assignment § 302-9.171 If circumstances warrant an authorization to... signed at the time of your assignment to the post of duty. Violation of that service agreement, however...

41 CFR 302-9.171 - If circumstances warrant an authorization to transport a POV to my post of duty after my...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES... Transportation Subsequent to the Time of Assignment § 302-9.171 If circumstances warrant an authorization to... signed at the time of your assignment to the post of duty. Violation of that service agreement, however...

41 CFR 302-9.171 - If circumstances warrant an authorization to transport a POV to my post of duty after my...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES... Transportation Subsequent to the Time of Assignment § 302-9.171 If circumstances warrant an authorization to... signed at the time of your assignment to the post of duty. Violation of that service agreement, however...

41 CFR 302-9.171 - If circumstances warrant an authorization to transport a POV to my post of duty after my...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES... Transportation Subsequent to the Time of Assignment § 302-9.171 If circumstances warrant an authorization to... signed at the time of your assignment to the post of duty. Violation of that service agreement, however...

41 CFR 302-9.171 - If circumstances warrant an authorization to transport a POV to my post of duty after my...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES... Transportation Subsequent to the Time of Assignment § 302-9.171 If circumstances warrant an authorization to... signed at the time of your assignment to the post of duty. Violation of that service agreement, however...

Multifactor valuation models of energy futures and options on futures

NASA Astrophysics Data System (ADS)

Bertus, Mark J.

The intent of this dissertation is to investigate continuous time pricing models for commodity derivative contracts that consider mean reversion. The motivation for pricing commodity futures and option on futures contracts leads to improved practical risk management techniques in markets where uncertainty is increasing. In the dissertation closed-form solutions to mean reverting one-factor, two-factor, three-factor Brownian motions are developed for futures contracts. These solutions are obtained through risk neutral pricing methods that yield tractable expressions for futures prices, which are linear in the state variables, hence making them attractive for estimation. These functions, however, are expressed in terms of latent variables (i.e. spot prices, convenience yield) which complicate the estimation of the futures pricing equation. To address this complication a discussion on Dynamic factor analysis is given. This procedure documents latent variables using a Kalman filter and illustrations show how this technique may be used for the analysis. In addition, to the futures contracts closed form solutions for two option models are obtained. Solutions to the one- and two-factor models are tailored solutions of the Black-Scholes pricing model. Furthermore, since these contracts are written on the futures contracts, they too are influenced by the same underlying parameters of the state variables used to price the futures contracts. To conclude, the analysis finishes with an investigation of commodity futures options that incorporate random discrete jumps.

Familiarizing with toy food: preliminary research and future directions.

PubMed

Lynch, Meghan

2012-01-01

A qualitative content analysis of children and parents interacting with toy food in their homes in view of recommendations for developing healthful food preferences. YouTube videos (n = 101) of children and parents interacting in toy kitchen settings were analyzed using qualitative content analysis. Toy food was categorized under 5 food groups, and interactions were compared to literature on developing healthful food preferences in children in real life. The most popular food group represented by the toys was Extras, followed by Fruits/Vegetables, Meats/Alternatives, Grains, and Milk/Dairy. Many parents were also found to encourage behaviors not conducive to healthful food preference development in children. Future research needs to determine whether familiarization with toy food influences children's real-life food preferences. Nutrition education programs for young children and parents could greatly benefit from future research on this approach. Exploring novel ways of developing children's food preferences is well warranted. Copyright © 2012 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

The Need for Future Alternatives: An Investigation of the Experiences and Future of Older Parents Caring for Offspring with Learning Disabilities over a Prolonged Period of Time

ERIC Educational Resources Information Center

Cairns, Deborah; Tolson, Debbie; Brown, Jayne; Darbyshire, Chris

2013-01-01

This article reports on the results of a qualitative study (in-depth interviews) carried out in the United Kingdom as part of a larger (two-phased) study investigating the experiences, health and future perspectives of older parent carers (six mothers and two fathers) of offspring with learning disabilities over a prolonged period of time. The…

Enhancing diversity in the public health research workforce: the research and mentorship program for future HIV vaccine scientists.

PubMed

Sopher, Carrie J; Adamson, Blythe Jane S; Andrasik, Michele P; Flood, Danna M; Wakefield, Steven F; Stoff, David M; Cook, Ryan S; Kublin, James G; Fuchs, Jonathan D

2015-04-01

We developed and evaluated a novel National Institutes of Health-sponsored Research and Mentorship Program for African American and Hispanic medical students embedded within the international, multisite HIV Vaccine Trials Network, and explored its impact on scientific knowledge, acquired skills, and future career plans. Scholars conducted social, behavioral, clinical, or laboratory-based research projects with HIV Vaccine Trials Network investigators over 8 to 16 weeks (track 1) or 9 to 12 months (track 2). We conducted an in-depth, mixed-methods evaluation of the first 2 cohorts (2011-2013) to identify program strengths, areas for improvement, and influence on professional development. A pre-post program assessment demonstrated increases in self-reported knowledge, professional skills, and interest in future HIV vaccine research. During in-depth interviews, scholars reported that a supportive, centrally administered program; available funding; and highly involved mentors and staff were keys to the program's early success. A multicomponent, mentored research experience that engages medical students from underrepresented communities and is organized within a clinical trials network may expand the pool of diverse public health scientists. Efforts to sustain scholar interest over time and track career trajectories are warranted.

Temperature impacts on economic growth warrant stringent mitigation policy

NASA Astrophysics Data System (ADS)

Moore, Frances C.; Diaz, Delavane B.

2015-02-01

Integrated assessment models compare the costs of greenhouse gas mitigation with damages from climate change to evaluate the social welfare implications of climate policy proposals and inform optimal emissions reduction trajectories. However, these models have been criticized for lacking a strong empirical basis for their damage functions, which do little to alter assumptions of sustained gross domestic product (GDP) growth, even under extreme temperature scenarios. We implement empirical estimates of temperature effects on GDP growth rates in the DICE model through two pathways, total factor productivity growth and capital depreciation. This damage specification, even under optimistic adaptation assumptions, substantially slows GDP growth in poor regions but has more modest effects in rich countries. Optimal climate policy in this model stabilizes global temperature change below 2 °C by eliminating emissions in the near future and implies a social cost of carbon several times larger than previous estimates. A sensitivity analysis shows that the magnitude of climate change impacts on economic growth, the rate of adaptation, and the dynamic interaction between damages and GDP are three critical uncertainties requiring further research. In particular, optimal mitigation rates are much lower if countries become less sensitive to climate change impacts as they develop, making this a major source of uncertainty and an important subject for future research.

Approaching the third decade of paediatric palliative oncology investigation: historical progress and future directions

PubMed Central

Rosenberg, Abby R; Wolfe, Joanne

2017-01-01

Paediatric palliative care (PPC) endeavours to alleviate the suffering and improve the quality of life of children with serious illnesses and their families. In the past two decades since WHO defined PPC and called for its inclusion in paediatric oncology care, rigorous investigation has provided important insights. For example, the first decade of research focused on end-of-life experiences of the child and the family, underscoring the high prevalence of symptom burden, the barriers to parent–provider concordance with regards to prognosis, as well as the need for bereavement supports. The second decade expanded PPC oncology investigation to include the entire cancer continuum and the voices of patients. Other studies identified the need for support of parents, siblings, and racial and ethnic minority groups. Promising interventions designed to improve outcomes were tested in randomised clinical trials. Future research will build on these findings and pose novel questions about how to continue to reduce the burdens of paediatric cancer. PMID:29333484

Renewable Electricity Futures Study. Volume 1. Exploration of High-Penetration Renewable Electricity Futures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, M. M.; Baldwin, S.; DeMeo, E.

2012-06-15

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%–90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT). Learn more at the RE Futures website. http://www.nrel.gov/analysis/re_futures/« less

Renewable Electricity Futures Study. Volume 1: Exploration of High-Penetration Renewable Electricity Futures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.; Wiser, R.; Sandor, D.

2012-06-01

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%-90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT).« less

An investigation of the role of current and future remote sensing data systems in numerical meteorology

NASA Technical Reports Server (NTRS)

Diak, George R.; Smith, William L.

1992-01-01

A flexible system for performing observing system simulation experiments which made contributions to meteorology across all elements of the observing system simulation experiment (OSSE) components was developed. Future work will seek better understanding of the links between satellite-measured radiation and radiative transfer in the clear, cloudy and precipitating atmosphere and investigate how that understanding might be applied to improve the depiction of the initial state and the treatment of physical processes in forecast models of the atmosphere.

Investigating future climate change impacts on drougt patterns over the Euro-Mediterranean area based on a probabilistic approach

NASA Astrophysics Data System (ADS)

Bonaccorso, Brunella; Peres, David Johnny; Cancelliere, Antonino

2017-04-01

As extensively documented by the IPCC assessment reports, impacts from recent climate-related extremes, such as heat waves, droughts, floods, cyclones and wildfires, reveal significant vulnerability of many environmental and anthropic systems to climate change. Compared to other extreme weather events, droughts evolve slowly in time. Based on this feature, effective drought preparedness and mitigation strategies could be implemented by decision makers, if appropriate tools, able to anticipate drought evolution in time and space, were available. Climate models' projections combined with probabilistic tools for drought characterization could help in understanding the time evolution of drought hazard in the future. Within the delineated context, the aim of the present study is to investigate potential scenarios of space-time variability of drought occurrences over Europe, by comparing the return periods of design drought events for different future time intervals. More specifically, annual precipitation data from Regional Climate Models (RCMs) of the Med-CORDEX initiative, covering the Euro-Mediterranean area (Northern Africa and Southern and Central Europe) at a grid resolution of about 50 km, are used to assess drought characteristics for three future periods (i.e. 2011-2040, 2041-2070 and 2071-2100), and compared to those in the baseline period (1971-2000). Specifically, three precipitation RCM datasets - produced by the CMMC (Euro-Mediterranean Center on Climate Change, IT), the LMD (Laboratorie del Météorologie Dynamique, FR) and the GUF (Goethe University Frankfurt, DE) - for two Representative Concentration Pathways, RCP 4.5 (intermediate) and RCP8.5 (high emissions), are considered for multi-year drought identification and characterization. First, the goodness of fit of several probability distributions to the considered precipitation gridded dataset is examined cell by cell by the Lilliefors test, and the best distribution is chosen for each cell based on

Is an aggressive surgical approach to the patient with gastric lymphoma warranted?

PubMed Central

Rosen, C B; van Heerden, J A; Martin, J K; Wold, L E; Ilstrup, D M

1987-01-01

At the Mayo Clinic, from 1970 through 1979, 84 patients (52 males and 32 females) had abdominal exploration for primary gastric lymphoma. All patients were observed a minimum of 5 years or until death. The histologic findings for all 84 patients were reviewed. Forty-four patients had "curative resection," and 40 patients had either biopsy alone or a palliative procedure. The probability of surviving 5 years was 75% for patients after potentially curative resection and 32% for patients after biopsy and palliation (p less than 0.001). The operative mortality rate was 5% overall and 2% after potentially curative resection. Increased tumor size (p less than 0.02), increased tumor penetration (p less than 0.01), and lymph node involvement (p less than 0.02) decreased the probability of survival, whereas histologic classification did not affect survival. Radiation therapy after surgery did not significantly affect the survival rate for the entire group or the survival rate for patients who had potentially curative resection. Resectability was associated with increased patient survival--independent of other prognostic factors--when our experience was analyzed by the Cox proportional-hazards model (p less than 0.005). It was concluded that an aggressive surgical attitude in the treatment of primary gastric lymphoma is warranted. The role of radiotherapy remains in question. PMID:3592805

Therapy of stress (takotsubo) cardiomyopathy: present shortcomings and future perspectives.

PubMed

Brunetti, Natale Daniele; Santoro, Francesco; De Gennaro, Luisa; Correale, Michele; Kentaro, Hayashi; Gaglione, Antonio; Di Biase, Matteo

2016-09-01

Several therapeutic options are available for the treatment of the acute phase of stress cardiomyopathy, pharmacological (β-blockers, diuretics, anticoagulants, antiarrhythmics, noncatecholamine inotropics [levosimendan]), and nonpharmacological (intra-aortic balloon pumping, extracorporeal membrane oxygenation), according to the wide possible clinical presentation and course of the disease. However, there is a gap in evidence, and very few data come from randomized and adequately powered studies. Some evidence supports the use of β-blockers, in particular with a short half-life, in the case of left ventricular outflow tract obstruction, and angiotensin-converting enzyme inhibitors in secondary prevention. Future perspectives include the study of genetic basis of stress cardiomyopathy, role of miRNA and neurovegetative modulation. Randomized studies, however, are surely warranted.

Faculty Turnover: Discipline-Specific Attention Is Warranted

ERIC Educational Resources Information Center

Xu, Yonghong Jade

2008-01-01

This study investigated the importance of discipline variations in understanding faculty turnover behaviors. A representative sample of university faculty in Research and Doctoral universities was obtained from a national database. Faculty members, self-identified into a primary academic area, were grouped into eight discipline clusters according…

Counter-regulation in affective attentional biases: a basic mechanism that warrants flexibility in emotion and motivation.

PubMed

Rothermund, Klaus; Voss, Andreas; Wentura, Dirk

2008-02-01

We investigated whether anticipating positive or negative future outcomes during goal pursuit has a modulatory effect on attentional biases for affectively congruent and incongruent distractor stimuli. In two experiments using a flanker task, we found that distractor interference of stimuli signaling opportunities or dangers was stronger after inducing an outcome focus of the opposite valence. The second experiment provided additional evidence that the incongruency effect reflects a global shift in affective attentional biases and is not mediated by changes in strategies or in the perceived valence of the stimuli. It is argued that counter-regulation in affective attentional biases serves an important function for the regulation of emotion and action.

Development of Electric Field and Plasma Wave Investigations for Future Space Weather Missions: ERG, SCOPE, and beyond

NASA Astrophysics Data System (ADS)

Kasaba, Y.; Kumamoto, A.; Ono, T.; Misawa, H.; Kojima, H.; Yagitani, S.; Kasahara, Y.; Ishisaka, K.

2009-04-01

The electric field and plasma wave investigation is important for the clarification of global plasma dynamics and energetic processes in the planetary Magnetospheric studies. We have several missions which will contribute those objectives. the small-sized radiation belt mission, ERG (Energization and Radiation in Geospace), the cross-scale formation flight mission, SCOPE, the BepiColombo mission to Mercury, and the small-sized and full-scale Jovian mission in future. Those will prevail the universal plasma mechanism and processes in the space laboratory. The main purposes of electric field and plasma wave observation for those missions are: (1) Examination of the theories of high-energy particle acceleration by plasma waves, (2) identification of the origin of electric fields in the magnetosphere associated with cross-scale coupling processes, (3) diagnosis of plasma density, temperature and composition, and (4) investigation of wave-particle interaction and mode conversion processes. Simultaneous observation of plasma waves and energetic particles with high resolution will enable us to investigate the wave-particle interaction based on quasi-linear theory and non-linear models. In this paper, we will summarize the current plan and efforts for those future activities. In order to achieve those objectives, the instrument including sensitive sensors (the long wire / stem antennae, the search-coil / loop antennae) and integrated receiver systems are now in development, including the direct identification of nonlinear wave-particle interactions associated will be tried by Wave-particle Correlator. And, as applications of those development, we will mention to the space interferometer and the radar sounder technologies.

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.

2012-11-01

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, M. M.

2012-09-01

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.

2013-04-01

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.

2012-10-01

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

SMARTPHONE-BASED DILATED FUNDUS PHOTOGRAPHY AND NEAR VISUAL ACUITY TESTING AS INEXPENSIVE SCREENING TOOLS TO DETECT REFERRAL WARRANTED DIABETIC EYE DISEASE.

PubMed

Toy, Brian C; Myung, David J; He, Lingmin; Pan, Carolyn K; Chang, Robert T; Polkinhorne, Alison; Merrell, Douglas; Foster, Doug; Blumenkranz, Mark S

2016-05-01

To compare clinical assessment of diabetic eye disease by standard dilated examination with data gathered using a smartphone-based store-and-forward teleophthalmology platform. 100 eyes of 50 adult patients with diabetes from a health care safety-net ophthalmology clinic. All patients underwent comprehensive ophthalmic examination. Concurrently, a smartphone was used to estimate near visual acuity and capture anterior and dilated posterior segment photographs, which underwent masked, standardized review. Quantitative comparison of clinic and smartphone-based data using descriptive, kappa, Bland-Altman, and receiver operating characteristic analyses was performed. Smartphone visual acuity was successfully measured in all eyes. Anterior and posterior segment photography was of sufficient quality to grade in 96 and 98 eyes, respectively. There was good correlation between clinical Snellen and smartphone visual acuity measurements (rho = 0.91). Smartphone-acquired fundus photographs demonstrated 91% sensitivity and 99% specificity to detect moderate nonproliferative and worse diabetic retinopathy, with good agreement between clinic and photograph grades (kappa = 0.91 ± 0.1, P < 0.001; AUROC = 0.97, 95% confidence interval, 0.93-1). The authors report a smartphone-based telemedicine system that demonstrated sensitivity and specificity to detect referral-warranted diabetic eye disease as a proof-of-concept. Additional studies are warranted to evaluate this approach to expanding screening for diabetic retinopathy.

Endoscopic vs. Surgical Interventions for Painful Chronic Pancreatitis: What is Needed for Future Clinical Trials

PubMed Central

Windsor, John A; Reddy, Nageshwar D

2017-01-01

The treatment of painful chronic pancreatitis remains controversial. The available evidence from two randomized controlled trials favor surgical intervention, whereas an endotherapy-first approach is widely practiced. Chronic pancreatitis is complex disease with different genetic and environmental factors, different pain mechanisms and different treatment modalities including medical, endoscopic, and surgical. The widely practiced step-up approach remains unproven. In designing future clinical trials there are some important pre-requisites including a more comprehensive pain assessment tool, the optimization of conservative medical treatment and interventional techniques. Consideration should be given to the need of a control arm and the optimal timing of intervention. Pending better designed studies, the practical way forward is to identify subgroups of patients who clearly warrant endotherapy or surgery first, and to design the future clinical trials for the remainder. PMID:28079861

The Relationships among Imagination, Future Imagination Tendency, and Future Time Perspective of Junior High School Students

ERIC Educational Resources Information Center

Tsai, Min-Ying

2015-01-01

The main purpose of the study were to investigate the relationships among imagination, future imagination tendency, and future time perspective of junior high school students, then to explore the future time perspective which is predicted by background variables, imaginative qualities, and future imagination tendency. The subjects were 331 from…

Eying the future: Eye movement in past and future thinking.

PubMed

El Haj, Mohamad; Lenoble, Quentin

2017-06-07

We investigated eye movement during past and future thinking. Participants were invited to retrieve past events and to imagine future events while their scan path was recorded by an eye-tracker. Past thinking triggered more fixation (p < .05), and saccade counts (p < .05) than future thinking. Past and future thinking triggered a similar duration of fixations and saccades, as well as a similar amplitude of saccades. Interestingly, participants rated past thinking as more vivid than future thinking (p < .01). Therefore, the vividness of past thinking seems to be accompanied by an increased number of fixations and saccades. Fixations and saccades in past thinking can be interpreted as an attempt by the visual system to find (through saccades) and activate (through fixations) stored memory representations. The same interpretation can be applied to future thinking as this ability requires activation of past experiences. However, future thinking triggers fewer fixations and saccades than past thinking: this may be due to its decreased demand on visual imagery, but could also be related to a potentially deleterious effect of eye movements on spatial imagery required for future thinking. Copyright © 2017 Elsevier Ltd. All rights reserved.

An Investigation of Senior Vocational School Students' Perceptions of the Future through Their Drawings

ERIC Educational Resources Information Center

Yukay Yuksel, Muge; Aksak, Meryem; Arican, Tugce; Bakan, Muhsin

2016-01-01

Problem Statement: Expectations/perceptions of the future are important concepts at every stage of life. However, these concepts become more important in adolescence, during which critical decisions about the future are made. Adolescents' expectations/perceptions of the future are vital from the perspectives of the families they live with, their…

The Future of Organized Camping.

ERIC Educational Resources Information Center

Henderson, Karla A.; And Others

A research study on the future of organized camping investigated future factors which may affect leadership of camping programs in Wisconsin and throughout the country. Objectives were to: identify 50 experts on organized camping who would participate in a 3-round Delphi study on the future of camping; generate consensus among the experts…

Present-day biogeochemical activities of anaerobic bacteria and their relevance to future exobiological investigations

USGS Publications Warehouse

Oremland, R.S.

1989-01-01

If the primordial atmosphere was reducing, then the first microbial ecosystem was probably composed of anaerobic bacteria. However, despite the presence of an oxygen-rich atmosphere, anaerobic habitats are important, commonplace components of the Earth's present biosphere. The geochemical activities displayed by these anaerobes impact the global cycling of certain elements (e.g., C, N, S, Fe, Mn, etc.). Methane provides an obvious example of how human-enhanced activities on a global scale can influence the content of a "radiative" (i.e., infrared absorbing) trace gas in the atmosphere. Methane can be oxidized by anaerobic bacteria, but this does not appear to support their growth. Acetylene, however, does support such growth. This may form the basis for future exobiological investigations of the atmospheres of anoxic, hydrocarbon-rich planets like Jupiter and Saturn, as well as the latter's satellite Titan. ?? 1989.

Motives for smoking in movies affect future smoking risk in middle school students: an experimental investigation.

PubMed

Shadel, William G; Martino, Steven C; Setodji, Claude; Haviland, Amelia; Primack, Brain A; Scharf, Deborah

2012-06-01

Exposure to smoking in movies has been linked to adolescent smoking uptake. However, beyond linking amount of exposure to smoking in movies with adolescent smoking, whether the way that smoking is portrayed in movies matters for influencing adolescent smoking has not been investigated. This study experimentally examined how motivation for smoking depicted in movies affects self-reported future smoking risk (a composite measure with items that assess smoking refusal self-efficacy and smoking intentions) among early adolescents. A randomized laboratory experiment was used. Adolescents were exposed to movie scenes depicting one of three movie smoking motives: social smoking motive (characters smoked to facilitate social interaction); relaxation smoking motive (characters smoked to relax); or no smoking motive (characters smoked with no apparent motive, i.e., in neutral contexts and/or with neutral affect). Responses to these movie scenes were contrasted (within subjects) to participants' responses to control movie scenes in which no smoking was present; these control scenes matched to the smoking scenes with the same characters in similar situations but where no smoking was present. A total of 358 adolescents, aged 11-14 years, participated. Compared with participants exposed to movie scenes depicting characters smoking with no clear motive, adolescents exposed to movie scenes depicting characters smoking for social motives and adolescents exposed to movie scenes depicting characters smoking for relaxation motives had significantly greater chances of having increases in their future smoking risk. Exposure to movies that portray smoking motives places adolescents at particular risk for future smoking. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Motives for Smoking in Movies Affect Future Smoking Risk in Middle School Students: An Experimental Investigation

PubMed Central

Shadel, William G.; Martino, Steven; Setodji, Claude; Haviland, Amelia; Primack, Brian; Scharf, Deborah

2011-01-01

Background Exposure to smoking in movies has been linked to adolescent smoking uptake. However, beyond linking amount of exposure to smoking in movies with adolescent smoking, whether the way that smoking is portrayed in movies matters for influencing adolescent smoking has not been investigated. This study experimentally examined how motivation for smoking depicted in movies affects self-reported future smoking risk (a composite measure with items that assess smoking refusal self-efficacy and smoking intentions) among early adolescents. Methods A randomized laboratory experiment was used. Adolescents were exposed to movie scenes depicting one of three movie smoking motives: social smoking motive (characters smoked to facilitate social interaction); relaxation smoking motive (characters smoked to relax); or no smoking motive (characters smoked with no apparent motive, i.e., in neutral contexts and/or with neutral affect). Responses to these movie scenes were contrasted (within subjects) to participants’ responses to control movie scenes in which no smoking was present; these control scenes matched to the smoking scenes with the same characters in similar situations but where no smoking was present. A total of 358 adolescents, aged 11–14 years, participated. Results Compared with participants exposed to movie scenes depicting characters smoking with no clear motive, adolescents exposed to movie scenes depicting characters smoking for social motives and adolescents exposed to movie scenes depicting characters smoking for relaxation motives had significantly greater chances of having increases in their future smoking risk. Conclusions Exposure to movies that portray smoking motives places adolescents at particular risk for future smoking. PMID:22074766

Renewable Electricity Futures Study. Executive Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.; Sandor, D.; Wiser, R.

2012-12-01

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%-90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT).« less

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, M. M.

2012-08-01

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented in a webinar given by the California Energy Commission.

Stochastic analysis of future vehicle populations

DOT National Transportation Integrated Search

1979-05-01

The purpose of this study was to build a stochastic model of future vehicle populations. Such a model can be used to investigate the uncertainties inherent in Future Vehicle Populations. The model, which is called the Future Automobile Population Sto...

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.

2012-08-01

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented in a Power Systems Engineering Research Center webinar on September 4, 2012.

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, M.; Mai, T.

2012-08-01

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented in an Union of Concerned Scientists webinar on June 12, 2012.

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, M.

2012-10-01

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It is being presented at the Utility Variable-Generation Integration Group Fall Technical Workshop on October 24, 2012.

Forecasting the burden of future postmenopausal hip fractures.

PubMed

Omsland, T K; Magnus, J H

2014-10-01

A growing elderly population is expected worldwide, and the rate of hip fractures is decisive for the future fracture burden. Significant declines in hip fracture rates in Norway, the USA, France, Germany, and the UK are required to counteract the impact of the ageing effects. This study aims to evaluate the consequences of the expected growth of the elderly population worldwide on the hip fracture burden using Norway as an example. Furthermore, we wanted to estimate the decline in hip fracture rates required to counteract the anticipated increase in the burden of hip fracture for Norway, the USA, France, Germany, and the UK. The burden of future postmenopausal hip fractures in Norway were estimated given (1) constant age-specific rates, (2) continued decline, and (3) different cohort scenarios. Based on population projection estimates and population age-specific hip fracture rates in women 65 years and older, we calculated the required declines in hip fracture rates needed to counteract the growing elderly populations in Norway, the USA, France, Germany, and the UK. The level of age-specific hip fracture rates had a huge impact on the future hip fracture burden in Norway. Even if the hip fracture rates decline at the same speed, a 22 % increase in the burden of hip fractures can be expected by 2040. An annual decline in hip fracture rates of 1.1-2.2 % until 2040 is required to counteract the effects of the growing elderly population on the future burden of hip fractures in Norway, the USA, France, Germany, and the UK. Hip fracture rates have a great impact on the burden of hip fractures. The rates will have to decline significantly to counteract the impact of a growing elderly population. A change in preventive strategies and further studies are warranted to identify the complex causes associated to hip fractures.

Investigation of crew motion disturbances on Skylab-Experiment T-013. [for future manned spacecraft design

NASA Technical Reports Server (NTRS)

Conway, B. A.

1974-01-01

Astronaut crew motions can produce some of the largest disturbances acting on a manned spacecraft which can affect vehicle attitude and pointing. Skylab Experiment T-013 was developed to investigate the magnitude and effects of some of these disturbances on the Skylab spacecraft. The methods and techniques used to carry out this experiment are discussed, and preliminary results of data analysis presented. Initial findings indicate that forces on the order of 300 N were exerted during vigorous soaring activities, and that certain experiment activities produced spacecraft angular rate excursions 0.03 to 0.07 deg/sec. Results of Experiment T-013 will be incorporated into mathematical models of crew-motion disturbances, and are expected to be of significant aid in the sizing, design, and analysis of stabilization and control systems for future manned spacecraft.

Focus on the future

NASA Technical Reports Server (NTRS)

Hanner, Martha S.

1988-01-01

An assessment is made of what was learned from Halley and recommendations are made for future directions for infrared studies of comets and supporting lab investigations. The following issues are addressed: (1) What steps can be taken to achieve consistent interpretation of Halley infrared data; (2) How successful has the Halley Watch been for infrared studies; (3) What supporting lab research is needed; (4) What are the key infrared observations needed for future comets; and (5) How do current and future NASA programs relate to comet studies.

45 CFR 150.303 - Basis for initiating an investigation of a potential violation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS... may be failing to meet an applicable HIPAA requirement, may warrant an investigation. CMS may consider... acting on that individual's behalf, may file a complaint with CMS if he or she believes that a right to...

Rewards and unique challenges faced by African-American custodial grandmothers: the importance of future planning.

PubMed

Crowther, Martha R; Huang, Chao-Hui Sylvia; Allen, Rebecca S

2015-01-01

This exploratory study examined the context and consequences of custodial grandparenting, along with attitudes and preferences regarding future planning among 22 African-American custodial grandmothers. A mixed-method research design was employed. Based on our integration of two theories regarding future planning and health behavior change, caregiving, emotional distress, religiosity and spirituality, and future planning were assessed using questionnaires along with semi-structured interviews. African-American custodial grandmothers (mean age M = 53.64, SD = 9.58) perceived their caregiving role as rewarding (72%) yet challenging (86%). More than 40% reported significant emotional distress (CES-D ≥ 16) that warrants clinical attention. Findings showed that while 64% of study participants had future plans regarding who will substitute in their caregiving role if they become incapacitated, only 9% had completed a living will. Three major themes emerged regarding custodial grandmothers' caregiving role which includes: (1) rewards; (2) challenges including feeling overwhelmed and health concerns; and (3) caregiving decisions including conflicts between 'My plan was…/put self on-hold' for grandchildren and difficulty with future planning. These themes highlighted the dynamics of caregiving across time, including current context and the ongoing process of decision-making. Findings suggest that while African-American custodial grandmothers find caregiving rewarding, they face unique challenges in contemplating and developing future plans. Custodial grandmothers think about substitute caregivers for their grandchildren but need assistance communicating a plan focused on their own needs for future care. Culturally sensitive interventions designed to facilitate effective utilization of future plans within this caregiver population are needed.

Predicting Future Suicide Attempts Among Adolescent and Emerging Adult Psychiatric Emergency Patients

PubMed Central

Horwitz, Adam G.; Czyz, Ewa K.; King, Cheryl A.

2014-01-01

Objective The purpose of this study was to longitudinally examine specific characteristics of suicidal ideation in combination with histories of suicide attempts and non-suicidal self-injury (NSSI) to best evaluate risk for a future attempt among high-risk adolescents and emerging adults. Method Participants in this retrospective medical record review study were 473 (53% female; 69% Caucasian) consecutive patients, ages 15–24 years (M = 19.4 years) who presented for psychiatric emergency (PE) services during a 9-month period. These patients’ medical records, including a clinician-administered Columbia-Suicide Severity Rating Scale, were coded at the index visit and at future visits occurring within the next 18 months. Logistic regression models were used to predict suicide attempts during this period. Results SES, suicidal ideation severity (i.e., intent, method), suicidal ideation intensity (i.e., frequency, controllability), a lifetime history of suicide attempt, and a lifetime history of NSSI were significant independent predictors of a future suicide attempt. Suicidal ideation added incremental validity to the prediction of future suicide attempts above and beyond the influence of a past suicide attempt, whereas a lifetime history of NSSI did not. Sex moderated the relationship between the duration of suicidal thoughts and future attempts (predictive for males, but not females). Conclusions Results suggest value in incorporating both past behaviors and current thoughts into suicide risk formulation. Furthermore, suicidal ideation duration warrants additional examination as a potential critical factor for screening assessments evaluating suicide risk among high-risk samples, particularly for males. PMID:24871489

Khat Use and Neurobehavioral Functions: Suggestions for Future Studies

PubMed Central

Hoffman, Richard; al’Absi, Mustafa

2010-01-01

Although there is a rich body of research available regarding the effect of acute and chronic khat dosing in animal models, research on the behavioral and cognitive effects of khat in human subjects is not extensive and several of the available studies have been done only in the context of observational and single-case studies. In light of the absence of a substantial literature on the neurobehavioral deficits associated with khat use and to provide a context that could be used to identify themes for future research we review previous research that has focused on other stimulant drugs. This review highlights multiple areas of neurocognitive deficit that have been identified in previous studies of individuals who have been chronic users of stimulants, such as amphetamines and methamphetamines. The review highlights a substantial body of evidence demonstrating a wide range of learning and memory impairments including deficits that persist during abstinence from active drug use. This review does not imply a similar khat effect, but due to some similarities pharmacologically between the active components of khat (cathinone and cathine) and amphetamines, future studies examining these same domains of cognitive functioning in chronic khat users and abstinent khat users appears to be warranted, if possible using some of the same or similar laboratory measures. PMID:20553832

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.

2012-08-01

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. This presentation was presented in a Wind Powering America webinar on August 15, 2012 and is now available through the Wind Powering America website.

Episodic Memory and Future Thinking During Early Childhood: Linking the Past and Future

PubMed Central

Cuevas, Kimberly; Rajan, Vinaya; Morasch, Katherine C.; Bell, Martha Ann

2015-01-01

Despite extensive examination of episodic memory and future thinking development, little is known about the concurrent emergence of these capacities during early childhood. In Experiment 1, 3-year-olds participated in an episodic memory hiding task [“what, when, where” (WWW) components] with an episodic future thinking component. In Experiment 2, a group of 4-year-olds (including children from Experiment 1) participated in the same task (different objects and locations), providing the first longitudinal investigation of episodic memory and future thinking. Although children exhibited age-related improvements in recall, recognition, and binding of the WWW episodic memory components, there were no age-related changes in episodic future thinking. At both ages, WWW episodic memory performance was higher than future thinking performance, and episodic future thinking and WWW memory components were unrelated. These findings suggest that the WWW components of episodic memory are potentially less fragile than the future components when assessed in a cognitively demanding task. PMID:25864990

Episodic memory and future thinking during early childhood: Linking the past and future.

PubMed

Cuevas, Kimberly; Rajan, Vinaya; Morasch, Katherine C; Bell, Martha Ann

2015-07-01

Despite extensive examination of episodic memory and future thinking development, little is known about the concurrent emergence of these capacities during early childhood. In Experiment 1, 3-year-olds participated in an episodic memory hiding task ("what, when, where" [WWW] components) with an episodic future thinking component. In Experiment 2, a group of 4-year-olds (including children from Experiment 1) participated in the same task (different objects and locations), providing the first longitudinal investigation of episodic memory and future thinking. Although children exhibited age-related improvements in recall, recognition, and binding of the WWW episodic memory components, there were no age-related changes in episodic future thinking. At both ages, WWW episodic memory performance was higher than future thinking performance, and episodic future thinking and WWW memory components were unrelated. These findings suggest that the WWW components of episodic memory are potentially less fragile than the future components when assessed in a cognitively demanding task. © 2015 Wiley Periodicals, Inc.

Clinician–Investigator Training and the Need to Pilot New Approaches to Recruiting and Retaining This Workforce

PubMed Central

Hall, Alison K.; Lund, P. Kay

2017-01-01

Clinician–investigators, also called physician–scientists, offer critical knowledge and perspectives that benefit research on basic science mechanisms, improved diagnostic and therapeutic approaches, population and outcomes medicine, health policy, and health services, yet few clinically trained health professionals pursue a research career. Sustaining this workforce requires attention to the unique challenges faced by investigators who must achieve clinical and research competence during training and their careers. These challenges include the duration of required clinical training, limited or discontinuous research opportunities, high levels of educational debt, balancing the dual obligations and rewards of clinical care and research, competition for research funding, and the need for leadership development after training. Women and individuals from underrepresented racial and ethnic groups comprise a small percentage of this workforce. The authors summarize the recent literature on training for clinician–investigators, emphasizing approaches with encouraging outcomes that warrant broader implementation. Using this overview as background, they convened three workshops at the National Institutes of Health in 2016 to identify and refine key priorities for potential new pilot programs to recruit and retain the clinician–investigator workforce. From these workshops emerged three priorities for future pilot programs: (1) support for research in residency, (2) new research on-ramps for health professionals at multiple career stages, and (3) national networks to diversify and sustain clinician–investigator faculty. Implementation of any pilot program will require coordinated commitment from academic health centers, medical licensing/certification boards, professional societies, and clinician–investigators themselves, in addition to support from the National Institutes of Health. PMID:28767499

Clinician-Investigator Training and the Need to Pilot New Approaches to Recruiting and Retaining This Workforce.

PubMed

Hall, Alison K; Mills, Sherry L; Lund, P Kay

2017-10-01

Clinician-investigators, also called physician-scientists, offer critical knowledge and perspectives that benefit research on basic science mechanisms, improved diagnostic and therapeutic approaches, population and outcomes medicine, health policy, and health services, yet few clinically trained health professionals pursue a research career. Sustaining this workforce requires attention to the unique challenges faced by investigators who must achieve clinical and research competence during training and their careers. These challenges include the duration of required clinical training, limited or discontinuous research opportunities, high levels of educational debt, balancing the dual obligations and rewards of clinical care and research, competition for research funding, and the need for leadership development after training. Women and individuals from underrepresented racial and ethnic groups comprise a small percentage of this workforce.The authors summarize the recent literature on training for clinician-investigators, emphasizing approaches with encouraging outcomes that warrant broader implementation. Using this overview as background, they convened three workshops at the National Institutes of Health in 2016 to identify and refine key priorities for potential new pilot programs to recruit and retain the clinician-investigator workforce. From these workshops emerged three priorities for future pilot programs: (1) support for research in residency, (2) new research on-ramps for health professionals at multiple career stages, and (3) national networks to diversify and sustain clinician-investigator faculty. Implementation of any pilot program will require coordinated commitment from academic health centers, medical licensing/certification boards, professional societies, and clinician-investigators themselves, in addition to support from the National Institutes of Health.

Investigation of Insulation Materials for Future Radioisotope Power Systems

NASA Technical Reports Server (NTRS)

Cornell, Peggy A.; Hurwitz, Frances I.; Ellis, David L.; Schmitz, Paul C.

2013-01-01

NASA's Radioisotope Power Systems (RPS) Technology Advancement Project is developing next generation high-temperature insulation materials that directly benefit thermal management and improve performance of RPS for future science missions. Preliminary studies on the use of multilayer insulation (MLI) for Stirling convertors used on the Advanced Stirling Radioisotope Generator (ASRG) have shown the potential benefits of MLI for space vacuum applications in reducing generator size and increasing specific power (W/kg) as compared to the baseline Microtherm HT (Microtherm, Inc.) insulation. Further studies are currently being conducted at NASA Glenn Research Center on candidate MLI foils and aerogel composite spacers. This paper presents the method of testing of foils and spacers and experimental results to date.

Component processes underlying future thinking.

PubMed

D'Argembeau, Arnaud; Ortoleva, Claudia; Jumentier, Sabrina; Van der Linden, Martial

2010-09-01

This study sought to investigate the component processes underlying the ability to imagine future events, using an individual-differences approach. Participants completed several tasks assessing different aspects of future thinking (i.e., fluency, specificity, amount of episodic details, phenomenology) and were also assessed with tasks and questionnaires measuring various component processes that have been hypothesized to support future thinking (i.e., executive processes, visual-spatial processing, relational memory processing, self-consciousness, and time perspective). The main results showed that executive processes were correlated with various measures of future thinking, whereas visual-spatial processing abilities and time perspective were specifically related to the number of sensory descriptions reported when specific future events were imagined. Furthermore, individual differences in self-consciousness predicted the subjective feeling of experiencing the imagined future events. These results suggest that future thinking involves a collection of processes that are related to different facets of future-event representation.

26 CFR 1.988-1 - Certain definitions and special rules.

Code of Federal Regulations, 2010 CFR

2010-04-01

... contract, futures contract, option, warrant, or similar financial instrument. (A) Limitation for certain derivative instruments. A forward contract, futures contract, option, warrant, or similar financial..., futures contract, option contract, or similar financial instrument. Except as otherwise provided in this...

Investigating Genomic Mechanisms of Treatment Resistance in Castration Resistant Prostate Cancer

DTIC Science & Technology

2013-05-01

warranting an elevated dose (1000mg twice daily). Blood is currently being collected for serum hormone levels , SNPs in androgen synthesis genes...Summary 3 . DATES COVERED 1 May 2012 – 30 April 2013 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Investigating Genomic Mechanisms of Treatment...to Androgen Biosynthesis Inhibitors in Men with Metastatic Castration Resistant Prostate Cancer. Notice of IRB approval. 3 . Curriculum Vitae

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

DeMeo, E.

2012-08-01

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented at Wind Powering America States Summit. The Summit, which follows the American Wind Energy Association's (AWEA's) annual WINDPOWER Conference and Exhibition, provides state Wind Working Groups, state energy officials, U.S. Energy Department and national laboratory representatives, and professional and institutional partners an opportunity to review successes, opportunities, and challenges for wind energy and plan future collaboration.

Evaluation of the Aviation Warrant Officer Advanced Course.

DTIC Science & Technology

1980-08-01

were reviewed to ascertain if any particular areas or subject blocks presented problems which should be investigated. (3) The Aviation Center Training...Analysis and Assistance Team (ACTAAT) Report revealed no trends/ problems relating to the AWOAC. (6) A review of course critiques from the previous class...explain what PET is and why it is important for leadership skills. Be able to list five goals in counseling and to know what they mean." 5 (c) The 27

The use of adenosine and adenosine triphosphate testing in the diagnosis, risk stratification and management of patients with syncope: current evidence and future perspectives.

PubMed

Fragakis, Nikolaos; Antoniadis, Antonios P; Saviano, Massimo; Vassilikos, Vassilios; Pappone, Carlo

2015-03-15

Syncope is a significant source of cardiovascular-related morbidity yet the etiology is frequently obscure and the identification of patients at highest risk is challenging. Adenosine (AD) and adenosine triphosphate (ATP) administrations have been suggested as potentially useful non-invasive tools in the diagnostic workup of patients with neurally-mediated or bradycardia-related syncope. It has been postulated that both compounds by modulating the autonomic innervation in the heart and exerting negative chronotropic and dromotropic effects in the conduction system, may unmask the mechanism of syncope. However, the clinical implications derived from the efficacy of both tests in the investigation of syncope remain unclear mainly due to inconclusive and occasionally contradictory results of published studies. This review article summarizes recent and past information in the use of ATP and AD in the investigation of syncope with emphasis on clinical trials. We present the current level of evidence for the use of these agents in clinical practice, identify areas where further research is warranted and highlight the future perspectives of these agents as complements to an accurate risk-stratification of patients with syncope. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

A Review of Current Investigations of Urban-Induced Rainfall and Recommendations for the Future

NASA Technical Reports Server (NTRS)

Shepherd, J. Marshall

2004-01-01

Precipitation is a key link in the global water cycle and a proxy for changing climate; therefore proper assessment of the urban environment s impact on precipitation (land use, aerosols, thermal properties) will be increasingly important in ongoing climate diagnostics and prediction, Global Water and Energy Cycle (GWEC) analysis and modeling, weather forecasting, freshwater resource management, urban planning-design and land-atmosphere-ocean interface processes. These facts are particularly critical if current projections for global urban growth are accurate. The goal of this paper is to provide a concise review of recent (1990-present) studies related to how the urban environment affects precipitation. In addition to providing a synopsis of current work, recent findings are placed in context with historical investigations such as METROMEX studies. Both observational and modeling studies of urban-induced rainfall are discussed. Additionally, a discussion of the relative roles of urban dynamic and microphysical (e.g. aerosol) processes is presented. The paper closes with a set of recommendations for what observations and capabilities are needed in the future to advance our understanding of the processes.

Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects

PubMed Central

Batchelor, Tracy T.; Reardon, David A.; de Groot, John F.; Wick, Wolfgang; Weller, Michael

2014-01-01

Glioblastoma is characterized by high expression levels of pro-angiogenic cytokines and microvascular proliferation, highlighting the potential value of treatments targeting angiogenesis. Antiangiogenic treatment likely achieves a beneficial impact through multiple mechanisms of action. Ultimately, however, alternative pro-angiogenic signal transduction pathways are activated leading to the development of resistance, even in tumors that initially respond. The identification of biomarkers or imaging parameters to predict response and to herald resistance is of high priority. Despite promising phase 2 clinical trial results and patient benefit in terms of clinical improvement and longer progression-free survival, an overall survival benefit has not been demonstrated in 4 randomized phase 3 trials of bevacizumab or cilengitide in newly diagnosed glioblastoma or cediranib or enzastaurin recurrent glioblastoma. However, future studies are warranted: predictive markers may allow appropriate patient enrichment, combination with chemotherapy may ultimately prove successful in improving overall survival, and novel agents targeting multiple pro-angiogenic pathways may prove effective. PMID:25398844

Perceiving the future news: Evidence for retrocausation

NASA Astrophysics Data System (ADS)

Graff, Dale E.; Cyrus, Patricia S.

2017-05-01

Thirty-three exploratory psi investigations were recently performed using Conscious State Psi and Dream State Psi protocols for photographic material that did not exist at the time of the psi sessions. Results would provide evidence for retrocausation if the future photographs had influenced the sessions' data. The psi targets were Associated Press (AP) news photographs published in a Reading, PA area newspaper on a specific page three days in the future. These photographs were taken one day after the psi sessions. Following each psi session, and prior to the photograph's existence, perceptions were recorded in project records and email transmitted for date validation. Feedback was provided when the photograph was published. There were two phases: Phase I was an informal investigation performed by the principle author to evaluate project feasibility. Phase II was a formal investigation with a colleague 1,000 miles from the principle author and the area newspaper location. All data were evaluated by direct comparison to the intended photographs using numerical assessment scales and noting unique features. Data from 21 of the 33 sessions (64%) yielded sketches and narratives with medium and high degrees of correlations with the future news photographs. A subsequent binary analysis using control photographs yielded p = 0.040. Visual informational content of these future newspaper photographs had interacted with the brain's cognitive processes in a retrocausal sense. The future photographs affected the sessions' data. A subconscious interaction between the future and the present or past may be an on-going feature of the mental and physical universe. Suggestions for follow-on investigations into retrocausation are provided.

Examining the Factors That Facilitate Athletic Training Faculty Socialization into Higher Education

ERIC Educational Resources Information Center

Mazerolle, Stephanie M.; Barrett, Jessica L.; Nottingham, Sara

2016-01-01

Context: Doctoral education is the mechanism whereby athletic trainers can develop an awareness of their future roles and responsibilities in higher education. Evidence suggests that doctoral education may provide an incomplete understanding of these roles and responsibilities, warranting further investigation. Objective: To gain a better…

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, M. M.

2012-08-01

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented to the 2012 Western Conference of Public Service Commissioners, during their June, 2012, meeting. The Western Conference of Public Service Commissioners is a regional association within the National Association of Regulatory Utility Commissioners (NARUC).

Investigation of Vehicle Requirements and Options for Future Space Tourism

NASA Technical Reports Server (NTRS)

Olds, John R.

2001-01-01

The research in support of this grant was performed by the PI, Dr. John Olds, and graduate students in the Space Systems Design Lab (SSDL) at Georgia Tech over the period December 1999 to December 2000. The work was sponsored by Dr. Ted Talay, branch chief of the Vehicle Analysis Branch at the NASA Langley Research Center. The objective of the project was to examine the characteristics of future space tourism markets and to identify the vehicle requirements that are necessary to enable this emerging new business segment.

Immune checkpoint inhibitors in urothelial cancer: recent updates and future outlook.

PubMed

Gopalakrishnan, Dharmesh; Koshkin, Vadim S; Ornstein, Moshe C; Papatsoris, Athanasios; Grivas, Petros

2018-01-01

Bladder cancer is the sixth most common cancer in the US and most tumors have urothelial (transitional cell) histology. Platinum-based chemotherapy has long been the standard of care in advanced disease, but long-term outcomes have largely remained poor. Since the peak incidence of bladder cancer is in the eighth decade of life and beyond, medical comorbidities may often limit the use of chemotherapy. Immune checkpoint inhibitors with their favorable toxicity profiles and notable antitumor activity have ushered in a new era in the treatment of advanced urothelial cancer (UC) with five agents targeting the PD-1/PD-L1 pathway being recently approved by the US Food and Drug administration. A plethora of clinical trials are ongoing in diverse disease settings, employing agents targeting PD-1/PD-L1 and related immune checkpoint pathways. While reactivating anti-tumor immunity, these agents may lead to a unique constellation of immune-related adverse events, which may warrant discontinuation of therapy and potential use of immunosuppression. Novel combinations with various treatment modalities and optimal sequencing of active therapies are being investigated in prospective clinical trials and retrospective registries. At the era of precision molecular medicine, and since patients do not respond uniformly to these agents, there is a growing need for identification and validation of biomarkers that can accurately predict treatment response and assist in patient selection. This review discusses current updates and future directions of immunotherapy in advanced UC.

Not my future? Core values and the neural representation of future events.

PubMed

Brosch, Tobias; Stussi, Yoann; Desrichard, Olivier; Sander, David

2018-06-01

Individuals with pronounced self-transcendence values have been shown to put greater weight on the long-term consequences of their actions when making decisions. Using functional magnetic resonance imaging, we investigated the neural mechanisms underlying the evaluation of events occurring several decades in the future as well as the role of core values in these processes. Thirty-six participants viewed a series of events, consisting of potential consequences of climate change, which could occur in the near future (around 2030), and thus would be experienced by the participants themselves, or in the far future (around 2080). We observed increased activation in anterior VMPFC (BA11), a region involved in encoding the personal significance of future events, when participants were envisioning far future events, demonstrating for the first time that the role of the VMPFC in future projection extends to the time scale of decades. Importantly, this activation increase was observed only in participants with pronounced self-transcendence values measured by self-report questionnaire, as shown by a statistically significant interaction of temporal distance and value structure. These findings suggest that future projection mechanisms are modulated by self-transcendence values to allow for a more extensive simulation of far future events. Consistent with this, these participants reported similar concern ratings for near and far future events, whereas participants with pronounced self-enhancement values were more concerned about near future events. Our findings provide a neural substrate for the tendency of individuals with pronounced self-transcendence values to consider the long-term consequences of their actions.

Final Work Plan: Phase I Investigation at Bladen, Nebraska

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, Lorraine M.; Yan, Eugene

The village of Bladen is a town of population approximately 237 in the northwest part of Webster County, Nebraska, 30 mi southwest of Hastings and 140 mi southwest of Lincoln, Nebraska. In 2000, the fumigant-related compound carbon tetrachloride was detected in public water supply well PWS 68-1, at a trace level. Low-level contamination, below the maximum contamination level (MCL) of 5.0 μg/L, has been detected intermittently in well PWS 68-1 since 2000, including in the last sample taken in July 2013. In 2006, the village installed a new well, PWS 2006-1, that remains free of contamination. Because the carbon tetrachloridemore » found in well PWS 68-1 might be linked to historical use of fumigants containing carbon tetrachloride at grain storage facilities, including its former facility in Bladen, the CCC/USDA is proposing an investigation to (1) delineate the source and extent of the carbon tetrachloride contamination potentially associated with its former facility, (2) characterize pathways and controlling factors for contaminant migration in the subsurface, and (3) establish a basis for estimating potential health and environmental risks. The work will be performed in accordance with the Intergovernmental Agreement established between the NDEQ and the Farm Service Agency of the USDA. The site investigation at Bladen will be implemented in phases, so that data collected and interpretations developed during each phase can be evaluated to determine if a subsequent phase of investigation is warranted and, if warranted, to provide effective guidance for the subsequent investigation activities. This Work Plan identifies the specific technical objectives and defines the scope of work proposed for the Phase I investigation by compiling and evaluating historical data. The proposed investigation activities will be performed on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research

A Future Fair: Building Tomorrow Today.

ERIC Educational Resources Information Center

Weatherly, Myra S.

1992-01-01

Gifted intermediate-level students in Greenville, South Carolina, held a Future Fair in which students completed projects and developed critical and creative thinking skills as they investigated real problems. Projects such as models, inventions, photo essays, and creative writing focused on future schools, art, fashions, space travel, and other…

Comprehensive management of pressure ulcers in spinal cord injury: Current concepts and future trends

PubMed Central

Kruger, Erwin A.; Pires, Marilyn; Ngann, Yvette; Sterling, Michelle; Rubayi, Salah

2013-01-01

Pressure ulcers in spinal cord injury represent a challenging problem for patients, their caregivers, and their physicians. They often lead to recurrent hospitalizations, multiple surgeries, and potentially devastating complications. They present a significant cost to the healthcare system, they require a multidisciplinary team approach to manage well, and outcomes directly depend on patients' education, prevention, and compliance with conservative and surgical protocols. With so many factors involved in the successful treatment of pressure ulcers, an update on their comprehensive management in spinal cord injury is warranted. Current concepts of local wound care, surgical options, as well as future trends from the latest wound healing research are reviewed to aid medical professionals in treating patients with this difficult problem. PMID:24090179

Renewable Electricity Futures (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mai, T.

2012-08-01

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented at the 2012 RE AMP Annual Meeting. RE-AMP is an active network of 144 nonprofits and foundations across eight Midwestern states working on climate change and energy policy with the goal of reducing global warming pollution economy-wide 80% by 2050.

Recent Successes and Future Directions in Immunotherapy of Cutaneous Melanoma

PubMed Central

Sadozai, Hassan; Gruber, Thomas; Hunger, Robert Emil; Schenk, Mirjam

2017-01-01

The global health burden associated with melanoma continues to increase while treatment options for metastatic melanoma are limited. Nevertheless, in the past decade, the field of cancer immunotherapy has witnessed remarkable advances for the treatment of a number of malignancies including metastatic melanoma. Although the earliest observations of an immunological antitumor response were made nearly a century ago, it was only in the past 30 years, that immunotherapy emerged as a viable therapeutic option, in particular for cutaneous melanoma. As such, melanoma remains the focus of various preclinical and clinical studies to understand the immunobiology of cancer and to test various tumor immunotherapies. Here, we review key recent developments in the field of immune-mediated therapy of melanoma. Our primary focus is on therapies that have received regulatory approval. Thus, a brief overview of the pathophysiology of melanoma is provided. The purported functions of various tumor-infiltrating immune cell subsets are described, in particular the recently described roles of intratumoral dendritic cells. The section on immunotherapies focuses on strategies that have proved to be the most clinically successful such as immune checkpoint blockade. Prospects for novel therapeutics and the potential for combinatorial approaches are delineated. Finally, we briefly discuss nanotechnology-based platforms which can in theory, activate multiple arms of immune system to fight cancer. The promising advances in the field of immunotherapy signal the dawn of a new era in cancer treatment and warrant further investigation to understand the opportunities and barriers for future progress. PMID:29276510

Reactors, Weapons, X-Rays, and Solar Panels: Using SCOT, Technological Frame, Epistemic Culture, and Actor Network Theory to Investigate Technology

ERIC Educational Resources Information Center

Sovacool, Benjamin K.

2006-01-01

The article explores how four different theories have been used to investigate technology. It highlights the worth and limitations of each theory and argues that an eclectic, ever-evolving approach to the study of technology is warranted. (Contains 1 table.)

Episodic Future Thinking in Children with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Terrett, Gill; Rendell, Peter G.; Raponi-Saunders, Sandra; Henry, Julie D.; Bailey, Phoebe E.; Altgassen, Mareike

2013-01-01

The capacity to imagine oneself experiencing future events has important implications for effective daily living but investigation of this ability in autism spectrum disorder (ASD) is limited. This study investigated future thinking in 30 children with high functioning ASD (IQ > 85) and 30 typically developing children. They completed the…

Report: Response to EPA Administrator’s Request for Investigation into Allegations of a Cover-up in the Risk Assessment for the Coal Ash Rulemaking

EPA Pesticide Factsheets

Report #10-N-0019, November 2, 2009. We closed this investigation because we found no evidence warranting additional inquiry into the rulemaking process for CCW disposal in landfills or surface impoundments.

Current and future graphics requirements for LaRC and proposed future graphics system

NASA Technical Reports Server (NTRS)

Taylor, N. L.; Bowen, J. T.; Randall, D. P.; Gates, R. L.

1984-01-01

The findings of an investigation to assess the current and future graphics requirements of the LaRC researchers with respect to both hardware and software are presented. A graphics system designed to meet these requirements is proposed.

Developing professional status: an investigation into the working patterns, working relationships and vision for the future of UK clinical dental technicians.

PubMed

Leyssen, W; Clark, R K F; Gallagher, J E; Radford, D R

2013-01-01

To investigate the working patterns and patient base of registered clinical dental technicians (CDTs); their relationships with dentists and other professionals in the dental team; their willingness to work within the NHS and their expectations for the future as a new professional group. Face-to-face qualitative interviews of registered CDTs, selected because of their geographic representation and mode of working, informed the development of a postal questionnaire survey of all early registrants with the General Dental Council (GDC). The majority of CDTs reported working part-time, often combining clinical practice with their role as a dental technician. They reported both positive and negative working relationships with dentists and dental technicians, demonstrating collaboration and/or competition depending on whether the scope of CDTs was respected and patient care was shared or lost. CDTs role in the NHS was limited because they did not have the status of becoming a recognised provider of dental care. There was a desire to expand their scope of practice in future. CDTs are embracing their new status as an occupational group within dentistry. Core features of becoming a professional group were exhibited including the importance of social and financial status and the need to negotiate their current and future roles in the healthcare system.

Investigation of dust particles with future Russian lunar missions: achievements of further development of PmL instrument.

NASA Astrophysics Data System (ADS)

Kuznetsov, Ilya; Zakharov, Alexander; Afonin, Valeri; Seran, Elena; Godefroy, Michel; Shashkova, Inna; Lyash, Andrey; Dolnikov, Gennady; Popel, Sergey; Lisin, Evgeny

2016-07-01

One of the complicating factors of the future robotic and human lunar landing missions is the influence of the dust. Meteorites bombardment has accompanied by shock-explosive phenomena, disintegration and mix of the lunar soil in depth and on area simultaneously. As a consequence, the lunar soil has undergone melting, physical and chemical transformations. Recently we have the some reemergence for interest of Moon investigation. The prospects in current century declare USA, China, India, and European Union. In Russia also prepare two missions: Luna-Glob and Luna-Resource. Not last part of investigation of Moon surface is reviewing the dust condition near the ground of landers. Studying the properties of lunar dust is important both for scientific purposes to investigation the lunar exosphere component and for the technical safety of lunar robotic and manned missions. The absence of an atmosphere on the Moon's surface is leading to greater compaction and sintering. Properties of regolith and dust particles (density, temperature, composition, etc.) as well as near-surface lunar exosphere depend on solar activity, lunar local time and position of the Moon relative to the Earth's magneto tail. Upper layers of regolith are an insulator, which is charging as a result of solar UV radiation and the constant bombardment of charged particles, creates a charge distribution on the surface of the moon: positive on the illuminated side and negative on the night side. Charge distribution depends on the local lunar time, latitude and the electrical properties of the regolith (the presence of water in the regolith can influence the local distribution of charge). On the day side of Moon near surface layer there exists possibility formation dusty plasma system. Altitude of levitation is depending from size of dust particle and Moon latitude. The distribution of dust particles by size and altitude has estimated with taking into account photoelectrons, electrons and ions of solar wind

Investigation of Insulation Materials for Future Radioisotope Power Systems (RPS)

NASA Technical Reports Server (NTRS)

Cornell, Peggy A.; Hurwitz, Frances I.; Ellis, David L.; Schmitz, Paul C.

2013-01-01

NASA's Radioisotope Power System (RPS) Technology Advancement Project is developing next generation high temperature insulation materials that directly benefit thermal management and improve performance of RPS for future science missions. Preliminary studies on the use of multilayer insulation (MLI) for Stirling convertors used on the Advanced Stirling Radioisotope Generator (ASRG) have shown the potential benefits of MLI for space vacuum applications in reducing generator size and increasing specific power (W/kg) as compared to the baseline Microtherm HT (Microtherm, Inc.) insulation. Further studies are currently being conducted at NASA Glenn Research Center (GRC) on candidate MLI foils and aerogel composite spacers. This paper presents the method of testing of foils and spacers and experimental results to date.

Sorghum production under future climate in the Southwestern USA: model projections of yield, greenhouse gas emissions and soil C fluxes

NASA Astrophysics Data System (ADS)

Duval, B.; Ghimire, R.; Hartman, M. D.; Marsalis, M.

2016-12-01

irrigated sorghum, and strong control of N rate on N2O emissions suggests that a dryland sorghum bioproduct system could be environmentally sustainable in the Southwestern US with effective N management, and warrants further investigation in field trials.

Amnesia and future thinking: Exploring the role of memory in the quantity and quality of episodic future thoughts.

PubMed

Cole, Scott N; Morrison, Catriona M; Barak, Ohr; Pauly-Takacs, Katalin; Conway, Martin A

2016-06-01

To examine the impact of memory accessibility on episodic future thinking. Single-case study of neurological patient HCM and an age-matched comparison group of neurologically Healthy Controls. We administered a full battery of tests assessing general intelligence, memory, and executive functioning. To assess autobiographical memory, the Autobiographical Memory Interview (Kopelman, Wilson, & Baddeley, 1990. The Autobiographical Memory Interview. Bury St. Edmunds, UK: Thames Valley Test Company) was administered. The Past Episodic and Future Episodic sections of Dalla Barba's Confabulation Battery (Dalla Barba, 1993, Cogn. Neuropsychol., 1, 1) and a specifically tailored Mental Time Travel Questionnaire were administered to assess future thinking in HCM and age-matched controls. HCM presented with a deficit in forming new memories (anterograde amnesia) and recalling events from before the onset of neurological impairment (retrograde amnesia). HCM's autobiographical memory impairments are characterized by a paucity of memories from Recent Life. In comparison with controls, two features of his future thoughts are apparent: Reduced episodic future thinking and outdated content of his episodic future thoughts. This article suggests neuropsychologists should look beyond popular conceptualizations of the past-future relation in amnesia via focussing on reduced future thinking. Investigating both the quantity and quality of future thoughts produced by amnesic patients may lead to developments in understanding the complex nature of future thinking disorders resulting from memory impairments. We highlight the clinical importance of examining the content of future thoughts in amnesic patients, rather than only its quantitative reduction. We propose an explanation of how quantitative and qualitative aspects of future thinking could be affected by amnesia. This could provide a useful approach to understand clinical cases of impaired prospection. Systematic group investigations

Silent Brain Infarction and Risk of Future Stroke: A Systematic Review and Meta-Analysis

PubMed Central

Gupta, Ajay; Giambrone, Ashley E.; Gialdini, Gino; Finn, Caitlin; Delgado, Diana; Gutierrez, Jose; Wright, Clinton; Beiser, Alexa S.; Seshadri, Sudha; Pandya, Ankur; Kamel, Hooman

2016-01-01

Background and Purpose Silent brain infarction (SBI) on magnetic resonance imaging (MRI) has been proposed as a subclinical risk marker for future symptomatic stroke. We performed a systematic review and meta-analysis to summarize the association between MRI-defined SBI and future stroke risk. Methods We searched the medical literature to identify cohort studies involving adults with MRI detection of SBI who were subsequently followed for incident clinically-defined stroke. Study data and quality assessment were recorded in duplicate with disagreements in data extraction resolved by a third reader. Strength association between MRI detected SBI and future symptomatic stroke measured by a hazard ratio (HR). Results The meta-analysis included 13 studies (14,764 subjects) with a mean follow-up ranging from 25.7 to 174 months. SBI predicted the occurrence of stroke with a random effects crude relative risk of 2.94 (95% CI 2.24–3.86, P<0.001; Q=39.65, P<0.001). In the eight studies of 10,427 subjects providing HR adjusted for cardiovascular risk factors, SBI was an independent predictor of incident stroke (HR 2.08 [95% CI 1.69–2.56, P<0.001]; Q=8.99, P=0.25). In a subgroup analysis pooling 9,483 stroke-free individuals from large population-based studies, SBI was present in ~18% of participants and remained a strong predictor of future stroke (HR 2.06 [95% CI 1.64–2.59], p<0.01). Conclusions SBI is present in approximately one in five stroke-free older adults and is associated with a 2-fold increased risk of future stroke. Future studies of in-depth stroke risk evaluations and intensive prevention measures are warranted in patients with clinically unrecognized radiologically evident brain infarctions. PMID:26888534

An investigation of the role of current and future remote sensing data systems in numerical meteorology

NASA Technical Reports Server (NTRS)

Diak, George R.; Smith, William L.

1993-01-01

The goals of this research endeavor have been to develop a flexible and relatively complete framework for the investigation of current and future satellite data sources in numerical meteorology. In order to realistically model how satellite information might be used for these purposes, it is necessary that Observing System Simulation Experiments (OSSEs) be as complete as possible. It is therefore desirable that these experiments simulate in entirety the sequence of steps involved in bringing satellite information from the radiance level through product retrieval to a realistic analysis and forecast sequence. In this project we have worked to make this sequence realistic by synthesizing raw satellite data from surrogate atmospheres, deriving satellite products from these data and subsequently producing analyses and forecasts using the retrieved products. The accomplishments made in 1991 are presented. The emphasis was on examining atmospheric soundings and microphysical products which we expect to produce with the launch of the Advanced Microwave Sounding Unit (AMSU), slated for flight in mid 1994.

Future-directed thinking in first-episode psychosis.

PubMed

Goodby, Emmeline; MacLeod, Andrew K

2016-06-01

This study employed the Future Thinking Task (MacLeod et al., 2005, Br. J. Clin. Psychol., 44, 495) to investigate whether future-directed thinking in first-episode psychosis is significantly different from that of matched controls, and to identify its correlates in this patient group. Cross-sectional, mixed-model, case-control design. Participants were 30 patients with first-episode psychosis and 27 matched controls. The Future Thinking Task was used to assess future-directed thinking in both groups. Anxiety and depression were also measured as well as self-report measures of hopelessness, suicide ideation and a measure of negative symptoms. Individuals with psychosis were impaired in future-directed thinking in both positive and negative domains, particularly with respect to the coming year. Increased self-reported hopelessness was associated with reduced positive future thinking and increased negative future thinking. Increased positive future thinking was also associated with reduced severity of negative symptoms, whilst negative future thinking was associated with suicide ideation. Individuals with first-episode psychosis show a reduction in positive future thinking in line with that seen in other clinical groups, but this is accompanied by an unexpected reduction in negative future thinking. The findings suggest a general disengagement with the future in this group that may affect recovery and functioning. Individuals with first-episode psychosis may benefit from interventions to help them engage with their future, in particular in the mid-range, up to 1 year. The Future Thinking Task may be a helpful addition to the assessment of suicide risk in those with first-episode psychosis. Decreased positive future thinking was associated with increased severity of negative symptoms, indicating a potential new treatment angle for this resistant aspect of psychosis. The cross-sectional design of this study does not allow for conclusions about the causal relationship

The Anticipated Positive Psychosocial Impact of Present Web-Based E-Health Services and Future Mobile Health Applications: An Investigation among Older Swedes.

PubMed

Wiklund Axelsson, S; Nyberg, L; Näslund, A; Melander Wikman, A

2013-01-01

This study investigates the anticipated psychosocial impact of present web-based e-health services and future mobile health applications among older Swedes. Random sample's of Swedish citizens aged 55 years old and older were given a survey containing two different e-health scenarios which respondents rated according to their anticipated psychosocial impact by means of the PIADS instrument. Results consistently demonstrated the positive anticipation of psychosocial impacts for both scenarios. The future mobile health applications scored more positively than the present web-based e-health services. An increase in age correlated positively to lower impact scores. These findings indicate that from a psychosocial perspective, web-based e-health services and mobile health applications are likely to positively impact quality of life. This knowledge can be helpful when tailoring and implementing e-health services that are directed to older people.

Current evidence and future directions for research with omega-3 fatty acids and attention deficit hyperactivity disorder.

PubMed

Gow, Rachel V; Hibbeln, Joseph R; Parletta, Natalie

2015-03-01

Nutritional insufficiencies of nutrients such as omega-3 highly unsaturated fatty acids (HUFAs), vitamins and minerals have been linked to suboptimal developmental outcomes including attention deficit hyperactivity disorder (ADHD). Although the predominant treatment is currently psychostimulant medications, randomized clinical trials with omega-3 HUFAs have reported small-to-modest effects in reducing symptoms of ADHD in children despite arguable individual methodological and design misgivings. This review presents, discusses and critically evaluates data and findings from meta-analytic and systematic reviews and clinical trials published within the last 12 months. Recent trajectories of this research are discussed, such as comparing eicosapentaenoic acid and docosahexaenoic acid and testing the efficacy of omega-3 HUFAs as an adjunct to methylphenidate. Discussion includes highlighting limitations and potential future directions such as addressing variable findings by accounting for other nutritional deficiencies and behavioural food intolerances. The authors conclude that given the current economic burden of ADHD, estimated in the region of $77 billion in the USA alone, in addition to the fact that a proportion of patients with ADHD are either treatment resistant, nonresponders or withdraw from medication because of adverse side-effects, the investigation of nonpharmacological interventions including omega-3 HUFAs in clinical practice warrants extrapolating.

Climatic Change--Past, Present & Future

ERIC Educational Resources Information Center

Lindholm, Roy C.

1976-01-01

Presented is a review of studies investigating factors affecting climatic changes in the Earth's atmosphere--past, present, and future. Dating methods, particularly the Oxygen 18/16 method, are discussed. (SL)

Risk perception of future cardiovascular disease in women diagnosed with a hypertensive disorder of pregnancy.

PubMed

Traylor, Jessica; Chandrasekaran, Suchitra; Limaye, Meghana; Srinivas, Sindhu; Durnwald, Celeste P

2016-01-01

The objective of this study is to evaluate a woman's risk perception for future cardiovascular disease (CVD) after being diagnosed with a hypertensive disorder of pregnancy. A prospective cohort of women diagnosed with a hypertensive disorder of pregnancy (HDP) was studied. Each woman completed two surveys, one prior to hospital discharge and one 2 weeks later, designed to assess knowledge of and risk perception for future CVD based on their recent diagnosis of a HDP. Rates of postpartum depression were also assessed. Of the 146 subjects included, 28% were diagnosed with preeclampsia with severe features, 52.1% with preeclampsia with mild features, and 19.9% had chronic hypertension. Women with severe features and those delivering preterm were more likely to report a perception of increased risk of both recurrent HDP in a future pregnancy (p = 0.004 and 0.005, respectively) and hypertension later in life (p = 0.01 and 0.03, respectively). Women delivering preterm were more likely to report an accurate perception of increased risk of myocardial infarction and stroke compared to those delivering at term (p = 0.006 and 0.002, respectively). Disease severity and preterm delivery were associated with a higher likelihood of the perception of an increased risk for both recurrent HDP and hypertension in the future. Only preterm delivery was associated with a higher risk perception for stroke and myocardial infarction. Interventions targeted at improved health awareness in women diagnosed with HDP are warranted.

Development of Electric Field Investigations for Future Missions in Japan: from Mercury, through Earth, toward Jupiter

NASA Astrophysics Data System (ADS)

Kasaba, Yasumasa

The electric field from DC to several 10s MHz is important for the clarification of global plasma dynamics, energetic processes, and wave-particle interactions in the planetary Magnetospheres by in-situ and remote sensing studies. We have developped the instruments for several missions, i.e., (1) BepiColombo Mercury Mag-netospheric Orbiter (MMO) to Mercury [just in FM development], (2) the small-sized radiation belt mission, ERG (Energization and Radiation in Geospace) [in EM design], (3) the cross-scale formation flight mission, SCOPE [in ceonceptual design], and (4) the future Jovian mission, EJSM, including JAXA Jupiter Magnetospheric Orbiter (JMO) and other elementss [in con-ceptual design]. Those will prevail the universal plasma mechanism and processes in the space laboratory. The common purposes of electric field, plasma waves, and radio waves observa-tion in those missions are: (a) Examination of the theories of high-energy particle acceleration by plasma waves, (b) identification of the origin of electric fields in the magnetosphere asso-ciated with cross-scale coupling processes, (c) diagnosis of plasma density, temperature and composition, and (d) investigation of wave-particle interaction and mode conversion processes. In order to achieve those objectives, the instrument including rigid antenna, wire antenna, and integrated receiver systems are now in development. Some of them were already used on the sounding rocket experiments (S310-23 launched by ISAS/JAXA) in 2007, and will also be used soon. As the applications of those development, we also try to adopt them to the space interferometer and the radar sounder. In this paper, we will summarize the current plan and efforts for those future activities.

A Longitudinal Analysis of the Indirect Effect of Violence Exposure on Future Orientation Through Perceived Stress and the Buffering Effect of Family Participation.

PubMed

Schmidt, Carissa J; Zimmerman, Marc A; Stoddard, Sarah A

2018-06-07

Exposure to violence (ETV) during adolescence has been associated with negative effects in later life, and may negatively affect an individual's future orientation. Future orientation has important health implications and warrants being studied. Yet, few researchers have examined how ETV affects an individual's future orientation as a young adult. The purpose of this study was to examine the indirect effect of ETV during adolescence on future orientation as a young adult through perceived stress. We also tested the moderating effect of family participation on the relationship between perceived stress and future orientation. Longitudinal data from a sample of 316 African American participants (42.10% male and 57.90% female, Mage = 14.76 at Wave 1) from low socioeconomic backgrounds recruited from a Midwestern school district were used in the analysis. Multigroup structural equation modeling (SEM) was used to test our hypotheses. Our findings indicated that greater ETV during adolescence is associated with higher levels of perceived stress and, in turn, a more negative outlook on one's future as a young adult. This indirect effect occurred for individuals with lower family participation, but was not evident for individuals with greater family participation. These findings provide important implications for youth development interventions. © Society for Community Research and Action 2018.

Teacher Education Futures: Today's Trends, Tomorrow's Expectations

ERIC Educational Resources Information Center

Aubusson, Peter; Schuck, Sandy

2013-01-01

Education is facing significant political and contextual challenges that will impact its future. This study employs a Delphi methodology to investigate teacher educators' views of current trends and their consequences for teacher education futures. Interviews were conducted with a sample of expert teacher educators drawn from eight countries. This…

An Experimental Investigation into NO sub X Control of a Gas Turbine Combustor and Augmentor Tube Incorporating a Catalytic Reduction System

DTIC Science & Technology

1990-03-01

An initial experimental investigation was conducted to examine the feasibility of NOx emission control using catalytic reduction techniques in the ...current configuration impractical. Recommendations for alternative configurations are presented. The results of the investigation have proven that further study is warranted....used as a gas generator and catalytic reduction system. Four data runs were made. Three runs were completed without the catalyst installed

Sleep disorders in adults with epilepsy: past, present, and future directions.

PubMed

Grigg-Damberger, Madeleine M; Ralls, Frank

2014-11-01

To summarize recent studies on the complex relationships between sleep disorders, sleep, and epilepsy. Insomnia in adults with epilepsy (AWE) warrants consideration of depression, anxiety, and suicidal ideation. Daytime sleepiness in AWE is more often due to undiagnosed sleep disorders. Sleep deprivation is an important provoker of seizures in juvenile myoclonic epilepsy. Abnormalities in frontal lobe executive function with difficulties making advantageous decisions may explain failure of juvenile myoclonic epilepsy patients to adhere to treatment recommendations and regulate their sleep habits. Sleep architecture in AWE is more likely to be abnormal if seizures are poorly controlled or occur during sleep. Obstructive sleep apnea is much more common in AWE who are man, older, heavier, or whose seizures are poorly controlled. Chronobiology and chronopharmacology of epilepsy is an emerging field worthy of future research and clinical applications. Identifying and treating unrecognized sleep disorders and understanding the impact of circadian rhythms on epilepsy can improve quality of life and seizure control in AWE.

Characteristics of real futures trading networks

NASA Astrophysics Data System (ADS)

Wang, Junjie; Zhou, Shuigeng; Guan, Jihong

2011-01-01

Futures trading is the core of futures business, and it is considered as one of the typical complex systems. To investigate the complexity of futures trading, we employ the analytical method of complex networks. First, we use real trading records from the Shanghai Futures Exchange to construct futures trading networks, in which nodes are trading participants, and two nodes have a common edge if the two corresponding investors appear simultaneously in at least one trading record as a purchaser and a seller, respectively. Then, we conduct a comprehensive statistical analysis on the constructed futures trading networks. Empirical results show that the futures trading networks exhibit features such as scale-free behavior with interesting odd-even-degree divergence in low-degree regions, small-world effect, hierarchical organization, power-law betweenness distribution, disassortative mixing, and shrinkage of both the average path length and the diameter as network size increases. To the best of our knowledge, this is the first work that uses real data to study futures trading networks, and we argue that the research results can shed light on the nature of real futures business.

Aerodynamic flight control to increase payload capability of future launch vehicles

NASA Technical Reports Server (NTRS)

Cochran, John E., Jr.

1995-01-01

The development of new launch vehicles will require that designers use innovative approaches to achieve greater performance in terms of pay load capability. The objective of the work performed under this delivery order was to provide technical assistance to the Contract Officer's Technical Representative (COTR) in the development of ideas and concepts for increasing the payload capability of launch vehicles by incorporating aerodynamic controls. Although aerodynamic controls, such as moveable fins, are currently used on relatively small missiles, the evolution of large launch vehicles has been moving away from aerodynamic control. The COTR reasoned that a closer investigation of the use of aerodynamic controls on large vehicles was warranted.

Papilloma diagnosed at MRI-guided vacuum-assisted breast biopsy: is surgical excision still warranted?

PubMed

Brennan, Sandra B; Corben, Adriana; Liberman, Laura; Dershaw, D David; Brogi, Edi; Van Zee, Kimberly J; Morris, Elizabeth

2012-10-01

The objective of our study was to determine the frequency of cancer at surgery in breast lesions yielding papilloma at MRI-guided 9-gauge vacuum-assisted biopsy (VAB) and to determine whether any features are associated with cancer upgrade. For this study, 1487 MRI-guided vacuum-assisted biopsies performed from January 2004 to March 2011 were reviewed. Lesions yielding papilloma were identified and classified as papilloma with or without atypia. Surgical findings were reviewed to determine the cancer rate. Statistical analysis was performed and 95% CIs were calculated. Papilloma was identified in 75 of the 1487 MRI-guided vacuum-assisted biopsies (5%). These 75 papillomas occurred in 73 women with a median age of 49 years (age range, 27-70 years). Of the 75 papillomas, 25 (33%) had atypia and 50 (67%) did not on core needle biopsy. Subsequent surgery of 67 of the 75 papillomas (89%) yielded ductal carcinoma in situ (DCIS) in four (6%; 95% CI, 2-15%). Surgery yielded DCIS in two of 23 papillomas with atypia (9%; 95% CI, 1-28%) at MRI-guided VAB and in two of 44 papillomas without atypia (5%; 95% CI, 0.4-16%) at MRI-guided VAB; these cancer rates did not differ significantly (p=0.6). Postmenopausal status (p=0.04) and histologic size of less than 0.2 cm (p=0.04) had a significant association with the cancer upgrade rate. Papilloma with or without atypia was found in 5% of patients who underwent MRI-guided VAB during the study period. Surgery revealed cancer in 6%. DCIS was found at surgery in 9% of lesions yielding papilloma with atypia versus 5% of lesions yielding papilloma without atypia. For lesions yielding papilloma with or without atypia at MRI-guided VAB, surgical excision is warranted.

Creating Futures Activity Cards and Teacher Guide.

ERIC Educational Resources Information Center

Klenzman, Elizabeth; Taylor, Paula

Teachers can use these learning activities to teach about the future in elementary and secondary social studies, science, math, language arts, and arts courses. The purpose of the activities is to help students practice creative-thinking skills, investigate problems relevant to their personal futures, experience the concept of change, and evaluate…

Delay of Gratification, Delay Discounting and their Associations with Age, Episodic Future Thinking, and Future Time Perspective.

PubMed

Göllner, Lars M; Ballhausen, Nicola; Kliegel, Matthias; Forstmeier, Simon

2017-01-01

The delay of gratification (DoG) in children is widely investigated with an experimental procedure originally called the "marshmallow test," whereas the studies on self-regulation (SR) in adolescents and adults usually use self-report questionnaires. Delay discounting (DD) measures simplify the DoG procedure and focus on monetary rewards. The aim of this study was to investigate age differences in DoG and DD from childhood to old age using a test that is suitable for both children and adults. Furthermore, investigations were conducted on the association between DoG/DD and two future orientation constructs [future time perspective (FTP) and episodic future thinking (EFT)] as well as age differences in these constructs. Participants from five age groups (9-14, 18-25, 35-55, 65-80, 80+) participated in the study ( N = 96). While we found no age difference for DoG, DD was the lowest [i.e., self-control (SC) was the highest] in young/middle adults; however, it was the highest (i.e., SC was the lowest) in children and old/oldest adults. Furthermore, we found significant age differences for DD and FTP. As predicted, there were strong correlations between DoG and FTP and between DD and FTP, but not between DoG/DD and EFT. These results indicate that age differences in SR vary across the measures used. Individuals who generally think and act in a future-oriented manner have a stronger ability to delay gratification.

Future versus present: time perspective and pupillary response in a relatedness judgment task investigating temporal event knowledge.

PubMed

Nowack, Kati; Milfont, Taciano L; van der Meer, Elke

2013-02-01

Mental representations of events contain many components such as typical agents, instruments, objects as well as a temporal dimension that is directed towards the future. While the role of temporal orientation (chronological, reverse) in event knowledge has been demonstrated by numerous studies, little is known about the influence of time perspective (present or future) as source of individual differences affecting event knowledge. The present study combined behavioral data with task-evoked pupil dilation to examine the impact of time perspective on cognitive resource allocation. In a relatedness judgment task, everyday events like raining were paired with an object feature like wet. Chronological items were processed more easily than reverse items regardless of time perspective. When more automatic processes were applied, greater scores on future time perspective were associated with lower error rates for chronological items. This suggests that a match between a strong focus on future consequences and items with a temporal orientation directed toward the future serves to enhance responding accuracy. Indexed by pupillary data, future-oriented participants invested more cognitive resources while outperforming present-oriented participants in reaction times across all conditions. This result was supported by a principal component analysis on the pupil data, which demonstrated the same impact of time perspective on the factor associated with more general aspects of cognitive effort. These findings suggest that future time perspective may be linked to a more general cognitive performance characteristic that improves overall task performance. Copyright © 2012 Elsevier B.V. All rights reserved.

Renewable Electricity Futures Study. Volume 3. End-Use Electricity Demand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hostick, Donna; Belzer, David B.; Hadley, Stanton W.

2012-06-15

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%–90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT). Learn more at the RE Futures website. http://www.nrel.gov/analysis/re_futures/« less

Renewable Electricity Futures Study. Volume 3: End-Use Electricity Demand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hostick, D.; Belzer, D.B.; Hadley, S.W.

2012-06-01

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%-90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT).« less

Futuring for Future Ready Librarians

ERIC Educational Resources Information Center

Figueroa, Miguel A.

2018-01-01

Futurists and foresight professionals offer several guiding principles for thinking about the future. These principles can help people to think about the future and become more powerful players in shaping the preferred futures they want for themselves and their communities. The principles also fit in well as strategies to support the Future Ready…

Phototriggerable Liposomes: Current Research and Future Perspectives

PubMed Central

Puri, Anu

2013-01-01

The field of cancer nanomedicine is considered a promising area for improved delivery of bioactive molecules including drugs, pharmaceutical agents and nucleic acids. Among these, drug delivery technology has made discernible progress in recent years and the areas that warrant further focus and consideration towards technological developments have also been recognized. Development of viable methods for on-demand spatial and temporal release of entrapped drugs from the nanocarriers is an arena that is likely to enhance the clinical suitability of drug-loaded nanocarriers. One such approach, which utilizes light as the external stimulus to disrupt and/or destabilize drug-loaded nanoparticles, will be the discussion platform of this article. Although several phototriggerable nanocarriers are currently under development, I will limit this review to the phototriggerable liposomes that have demonstrated promise in the cell culture systems at least (but not the last). The topics covered in this review include (i) a brief summary of various phototriggerable nanocarriers; (ii) an overview of the application of liposomes to deliver payload of photosensitizers and associated technologies; (iii) the design considerations of photoactivable lipid molecules and the chemical considerations and mechanisms of phototriggering of liposomal lipids; (iv) limitations and future directions for in vivo, clinically viable triggered drug delivery approaches and potential novel photoactivation strategies will be discussed. PMID:24662363

Phase II drugs under clinical investigation for the treatment of chronic constipation.

PubMed

Mozaffari, Shilan; Didari, Tina; Nikfar, Shekoufeh; Abdollahi, Mohammad

2014-11-01

Chronic constipation (CC) is a common gastrointestinal (GI) motility disorder that significantly impairs the quality of life in affected subjects. As almost half of the patients suffering from CC are not satisfied with currently available medicines, there is a need to develop new molecules with better effectiveness and tolerability. The authors include all experimental and clinical trials (up to Phase II) about new investigational drugs for the treatment of CC. The article identifies nine new agents: mitemcinal, TD-8954, YKP10811, itopride, RM-131, KWA-0711, elobixibat, velusetrag, and naronapride. All nine agents have shown prokinetic effects in different stages of the development. The mechanisms of new developing drugs include: the activation of 5-hydroxytryptamine type-4 (5-HT4), ghrelin and motilin receptors, antagonizing dopamine type-2 (D2) receptors, inhibition of ileal bile acid reabsorption and acetylcholine esterase, as well as water absorption from the GI tract. At this current point in time, new generations of 5-HT4 receptor agonists (velusetrag, noranopride and YKP10811) are hoped to progress, further in the future, due to better efficiency and safety. However, it is not possible to make a concise conclusion at this current time due to a lack of evidence. Further clinical trials with a longer duration and a larger sample size are warranted.

Planning Future Clinical Trials for Machado-Joseph Disease.

PubMed

Saute, Jonas Alex Morales; Jardim, Laura Bannach

2018-01-01

Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant multiple neurological systems degenerative disorder caused by a CAG repeat expansion at ATXN3 gene. Only a few treatments were evaluated in randomized clinical trials (RCT) in SCA3/MJD patients, with a lack of evidence for both disease-modifying and symptomatic therapies. The present chapter discuss in detail major methodological issues for planning future RCT for SCA3/MJD. There are several potential therapies for SCA3/MJD with encouraging preclinical results. Route of treatment, dosage titration and potential therapy biomarkers might differ among candidate drugs; however, the core study design and protocol will be mostly the same. RCT against placebo group is the best study design to test a disease-modifying therapy; the same cannot be stated for some symptomatic treatments. Main outcomes for future RCT are clinical scales: the Scale for the Assessment and Rating of ataxia (SARA) is currently the instrument of choice to prove efficacy of disease-modifying or symptomatic treatments against ataxia, the most important disease feature. Ataxia quantitative scales or its composite scores can be used as primary outcomes to provide preliminary evidence of efficacy in phase 2 RCT, due to a greater sensitivity to change. Details regarding eligibility criteria, randomization, sample size estimation, duration and type of analysis for both disease modifying and symptomatic treatment trials, were also discussed. Finally, a section anticipates the methodological issues for testing novel drugs when an effective treatment is already available. We conclude emphasizing four points, the first being the need of RCT for a number of different aims in the care of SCA3/MJD. Due to large sample sizes needed to warrant power, RCT for disease-modifying therapies should be multicenter enterprises. There is an urge need for surrogate markers validated for several drug classes. Finally, engagement of at

Conceptual Paradigms and Empirical Investigations for Evaluating INTELSAT's Past Performance and Future Prospects.

ERIC Educational Resources Information Center

Snow, Marcellus S.

This paper summarizes the results of a recent study of the past performance and future prospects of the International Telecommunications Satellite (INTELSAT) Organization. First, an overview of INTELSAT's history is provided and major policy issues are detailed. Five alternative paradigms are then presented through which to evaluate INTELSAT's…

Delay of Gratification, Delay Discounting and their Associations with Age, Episodic Future Thinking, and Future Time Perspective

PubMed Central

Göllner, Lars M.; Ballhausen, Nicola; Kliegel, Matthias; Forstmeier, Simon

2018-01-01

The delay of gratification (DoG) in children is widely investigated with an experimental procedure originally called the “marshmallow test,” whereas the studies on self-regulation (SR) in adolescents and adults usually use self-report questionnaires. Delay discounting (DD) measures simplify the DoG procedure and focus on monetary rewards. The aim of this study was to investigate age differences in DoG and DD from childhood to old age using a test that is suitable for both children and adults. Furthermore, investigations were conducted on the association between DoG/DD and two future orientation constructs [future time perspective (FTP) and episodic future thinking (EFT)] as well as age differences in these constructs. Participants from five age groups (9–14, 18–25, 35–55, 65–80, 80+) participated in the study (N = 96). While we found no age difference for DoG, DD was the lowest [i.e., self-control (SC) was the highest] in young/middle adults; however, it was the highest (i.e., SC was the lowest) in children and old/oldest adults. Furthermore, we found significant age differences for DD and FTP. As predicted, there were strong correlations between DoG and FTP and between DD and FTP, but not between DoG/DD and EFT. These results indicate that age differences in SR vary across the measures used. Individuals who generally think and act in a future-oriented manner have a stronger ability to delay gratification. PMID:29422875

Metastatic melanoma - a review of current and future drugs.

PubMed

Velho, Tiago Rodrigues

2012-11-19

Melanoma is one of the most aggressive cancers, and it is estimated that 76,250 men and women will be diagnosed with melanoma of the skin in the USA in 2012. Over the last few decades many drugs have been developed but only in 2011 have new drugs demonstrated an impact on survival in metastatic melanoma. A systematic search of literature was conducted, and studies providing data on the effectiveness of current and/or future drugs used in the treatment of metastatic melanoma were selected for review. This review discusses the advantages and limitations of these agents, evaluating past, current and future clinical trials designed to overcome such limitations. To date, there are four drugs approved by the Food and Drug Administration for melanoma (dacarbazine, interleukin-2, ipilimumab and vemurafenib). Despite efforts to develop new drugs, few of them have demonstrated any clinical benefits. Approved in 1975, dacarbazine remains the gold standard in chemotherapy, although ipilimumab and vemurafenib have raised many hopes in the last few years. Combining dacarbazine or other chemotherapy agents with new pharmacological agents may be a new way to achieve better clinical responses in patients with metastatic melanoma. Advances in the molecular knowledge of melanoma have led to major improvements in the treatment of patients with metastatic melanoma, providing new targets and insights. However, heterogeneity amongst study populations, different approaches to treatment and the different melanoma types and localisations included in the trials makes their comparison difficult. New studies focusing on drugs developed in recent decades are warranted.

Parent Refusal of Topical Fluoride for Their Children: Clinical Strategies and Future Research Priorities to Improve Evidence-Based Pediatric Dental Practice.

PubMed

Chi, Donald L

2017-07-01

A growing number of parents are refusing topical fluoride for their children during preventive dental and medical visits. This nascent clinical and public health problem warrants attention from dental professionals and the scientific community. Clinical and community-based strategies are available to improve fluoride-related communications with parents and the public. In terms of future research priorities, there is a need to develop screening tools to identify parents who are likely to refuse topical fluoride and diagnostic instruments to uncover the reasons for topical fluoride refusal. This knowledge will lead to evidence-based strategies that can be widely disseminated into clinical practice. Copyright © 2017 Elsevier Inc. All rights reserved.

A preliminary investigation of bird classification by Doppler radar

NASA Technical Reports Server (NTRS)

Martinson, L. W.

1973-01-01

A preliminary study of the application of Doppler radar to the classification of birds is reported. The desirability for improvements in bird classification stems primarily from the hazards they present to jet aircraft in flight and in the vicinity of airports. A secondary need exists in the study of bird migration. The wing body and tail motion of a bird in flight reflect signals which, when analyzed properly present a signature of wing beat pattern which is unique for each bird species. Although the results of this investigation did not validate the feasibility of classifying bird species, they do indicate that a more thorough investigation is warranted. Certain gross characteristics such as wing beat rates, multiple bird patterns, and bird maneuverability, were indicated clearly in the results. Large birds with slow wing beat rates appear to be the most optimum subject for further study with the X-band Doppler radar used in this investigation.

Groundwater quality, age, and susceptibility and vulnerability to nitrate contamination with linkages to land use and groundwater flow, Upper Black Squirrel Creek Basin, Colorado, 2013

USGS Publications Warehouse

Wellman, Tristan P.; Rupert, Michael G.

2016-03-03

The results of this investigation offer the foundational information needed for developing best management practices to mitigate nitrate contamination, basic concepts on water quality to aid public education, and information to guide regulatory measures if policy makers determine this is warranted. Science-based decision making will require continued monitoring and analysis of water quality in the future.

Biological invasion hotspots: a trait-based perspective reveals new sub-continental patterns

Treesearch

Basil V. Iannone III; Kevin M. Potter; Qinfeng Guo; Andrew M. Liebhold; Bryan C. Pijanowski; Christopher M. Oswalt; Songlin Fei

2015-01-01

Invader traits (including plant growth form) may play an important, and perhaps overlooked, role in determining macroscale patterns of biological invasions and therefore warrant greater consideration in future investigations aimed at understanding these patterns. To assess this need, we used empirical data from a national-level survey of forest in the contiguous 48...

Episodic future thinking and future-based decision-making in a case of retrograde amnesia.

PubMed

De Luca, Flavia; Benuzzi, Francesca; Bertossi, Elena; Braghittoni, Davide; di Pellegrino, Giuseppe; Ciaramelli, Elisa

2018-02-01

We investigated episodic future thinking (EFT) and future-based cognition and decision-making in patient SG, who developed a dense retrograde amnesia following hypoxia due to a cardiac arrest. Despite intact general cognitive and executive functioning, SG was unable to remember events from his entire lifetime. He had, however, relatively spared anterograde memory and general semantic knowledge. Voxel-based morphometry detected a reduction of gray matter in the thalamus, cerebellum and fusiform gyrus bilaterally, and, at a reduced threshold, in several regions of the autobiographical memory network, including the hippocampi. We show that SG is unable to imagine personal future events, but can imagine fictitious events not self-relevant and not located in subjective time. Despite severely impaired EFT, SG shows normal attitudes towards the future time, and normal delay discounting rates. These findings suggest that retrieval of autobiographical information from long-term memory is necessary for EFT. However, relatively spared anterograde memory and general semantic knowledge may be sufficient to allow construction of fictitious experiences. As well, EFT is not necessary to drive future-oriented cognition and choice. These findings highlight the relation between autobiographical memory and EFT, and the fractionation of human temporal consciousness. Moreover, they contribute to our understanding of retrograde amnesia as an impairment of memory as well as future thinking. Copyright © 2017 Elsevier Ltd. All rights reserved.

FutureCoast: "Listen to your futures"

NASA Astrophysics Data System (ADS)

Pfirman, S. L.; Eklund, K.; Thacher, S.; Orlove, B. S.; Diane Stovall-Soto, G.; Brunacini, J.; Hernandez, T.

2014-12-01

Two science-arts approaches are emerging as effective means to convey "futurethinking" to learners: systems gaming and experiential futures. FutureCoast exemplifies the latter: by engaging participants with voicemails supposedly leaking from the cloud of possible futures, the storymaking game frames the complexities of climate science in relatable contexts. Because participants make the voicemails themselves, FutureCoast opens up creative ways for people to think about possibly climate-changed futures and personal ways to talk about them. FutureCoast is a project of the PoLAR Partnership with a target audience of informal adult learners primarily reached via mobile devices and online platforms. Scientists increasingly use scenarios and storylines as ways to explore the implications of environmental change and societal choices. Stories help people make connections across experiences and disciplines and link large-scale events to personal consequences. By making the future seem real today, FutureCoast's framework helps people visualize and plan for future climate changes. The voicemails contributed to FutureCoast are spread through the game's intended timeframe (2020 through 2065). Based on initial content analysis of voicemail text, common themes include ecosystems and landscapes, weather, technology, societal issues, governance and policy. Other issues somewhat less frequently discussed include security, food, industry and business, health, energy, infrastructure, water, economy, and migration. Further voicemail analysis is examining: temporal dimensions (salient time frames, short vs. long term issues, intergenerational, etc.), content (adaptation vs. mitigation, challenges vs. opportunities, etc.), and emotion (hopeful, resigned, etc. and overall emotional context). FutureCoast also engaged audiences through facilitated in-person experiences, geocaching events, and social media (Tumblr, Twitter, Facebook, YouTube). Analysis of the project suggests story

Performance of warranted asphalt pavements : smoothness and performance of Indiana warranted asphalt pavements.

DOT National Transportation Integrated Search

2016-06-01

In the early 1990s the Indiana Department of Transportation (INDOT) developed a five-year warranty specification for asphalt pavements : with the first project being built in 1996. In 2004, results indicated that the asphalt pavements built with the ...

The Future of Wind Energy in California: Future Projections in Variable-Resolution CESM

NASA Astrophysics Data System (ADS)

Wang, M.; Ullrich, P. A.; Millstein, D.; Collier, C.

2017-12-01

This study focuses on the wind energy characterization and future projection at five primary wind turbine sites in California. Historical (1980-2000) and mid-century (2030-2050) simulations were produced using the Variable-Resolution Community Earth System Model (VR-CESM) to analyze the trends and variations in wind energy under climate change. Datasets from Det Norske Veritas Germanischer Llyod (DNV GL), MERRA-2, CFSR, NARR, as well as surface observational data were used for model validation and comparison. Significant seasonal wind speed changes under RCP8.5 were detected from several wind farm sites. Large-scale patterns were then investigated to analyze the synoptic-scale impact on localized wind change. The agglomerative clustering method was applied to analyze and group different wind patterns. The associated meteorological background of each cluster was investigated to analyze the drivers of different wind patterns. This study improves the characterization of uncertainty around the magnitude and variability in space and time of California's wind resources in the near future, and also enhances understanding of the physical mechanisms related to the trends in wind resource variability.

Fate of Articles That Warranted Retraction Due to Ethical Concerns: A Descriptive Cross-Sectional Study

PubMed Central

Elia, Nadia; Wager, Elizabeth; Tramèr, Martin R.

2014-01-01

Objective To study journals' responses to a request from the State Medical Association of Rheinland-Pfalz, Germany, to retract 88 articles due to ethical concerns, and to check whether the resulting retractions followed published guidelines. Design Descriptive cross-sectional study. Population 88 articles (18 journals) by the anaesthesiologist Dr. Boldt, that warranted retraction. Method According to the recommendations of the Committee on Publication Ethics, we regarded a retraction as adequate when a retraction notice was published, linked to the retracted article, identified the title and authors of the retracted article in its heading, explained the reason and who took responsibility for the retraction, and when the retracted article was freely accessible and marked using a transparent watermark that preserved original content. Two authors extracted data independently (January 2013) and contacted editors-in-chief and publishers for clarification in cases of inadequate retraction. Results Five articles (6%) fulfilled all criteria for adequate retraction. Nine (10%) were not retracted (no retraction notice published, full text article not marked). 79 (90%) retraction notices were published, 76 (86%) were freely accessible, but only 15 (17%) were complete. 73 (83%) full text articles were marked as retracted, of which 14 (16%) had an opaque watermark hiding parts of the original content, and 11 (13%) had all original content deleted. 59 (67%) retracted articles were freely accessible. One editor-in-chief stated personal problems as a reason for incomplete retractions, eight blamed their publishers. Two publishers cited legal threats from Dr. Boldt's co-authors which prevented them from retracting articles. Conclusion Guidelines for retracting articles are incompletely followed. The role of publishers in the retraction process needs to be clarified and standards are needed on marking retracted articles. It remains unclear who should check that retractions are done

Outbreak investigations--a perspective.

PubMed Central

Reingold, A. L.

1998-01-01

Outbreak investigations, an important and challenging component of epidemiology and public health, can help identify the source of ongoing outbreaks and prevent additional cases. Even when an outbreak is over, a thorough epidemiologic and environmental investigation often can increase our knowledge of a given disease and prevent future outbreaks. Finally, outbreak investigations provide epidemiologic training and foster cooperation between the clinical and public health communities. PMID:9452395

Phenomenological Characteristics of Future Thinking in Alzheimer's Disease.

PubMed

Moustafa, Ahmed A; El Haj, Mohamad

2018-05-11

This study investigates phenomenological reliving of future thinking in Alzheimer's disease (AD) patients and matched controls. All participants were asked to imagine in detail a future event, and afterward, were asked to rate phenomenological characteristics of their future thinking. As compared to controls, AD participants showed poor rating for reliving, travel in time, visual imagery, auditory imagery, language, and spatiotemporal specificity. However, no significant differences were observed between both groups in emotion and importance of future thinking. Results also showed lower rating for visual imagery relative to remaining phenomenological features in AD participants compared to controls; conversely, these participants showed higher ratings for emotion and importance of future thinking. AD seems to compromise some phenomenological characteristics of future thinking, especially, visual imagery; however, other phenomenological characteristics, such as emotion, seem to be relatively preserved in these populations. By highlighting the phenomenological experience of future thinking in AD, our paper opens a unique window into the conscious experience of the future in AD patients.

What differentiates episodic future thinking from complex scene imagery?

PubMed

de Vito, Stefania; Gamboz, Nadia; Brandimonte, Maria A

2012-06-01

We investigated the contributions of familiarity of setting, self-relevance and self-projection in time to episodic future thinking. The role of familiarity of setting was assessed, in Experiment 1, by comparing episodic future thoughts to autobiographical future events supposed to occur in unfamiliar settings. The role of self-relevance was assessed, in Experiment 2, by comparing episodic future thoughts to future events involving familiar others. The role of self-projection in time was assessed, in both Experiments, by comparing episodic future thoughts to autobiographical events that were not temporal in nature. Results indicated that episodic future thoughts were more clearly represented than autobiographical future events occurring in unfamiliar setting and future events involving familiar others. Our results also revealed that episodic future thoughts were indistinguishable from autobiographical atemporal events with respect to both subjective and objective detail ratings. These results suggest that future and atemporal events are mentally represented in a similar way. Copyright © 2012 Elsevier Inc. All rights reserved.

Adult-onset offenders: Is a tailored theory warranted?

PubMed Central

Beckley, Amber L.; Caspi, Avshalom; Harrington, Honalee; Houts, Renate M.; Mcgee, Tara Renae; Morgan, Nick; Schroeder, Felix; Ramrakha, Sandhya; Poulton, Richie; Moffitt, Terrie E.

2016-01-01

Purpose To describe official adult-onset offenders, investigate their antisocial histories and test hypotheses about their origins. Methods We defined adult-onset offenders among 931 Dunedin Study members followed to age 38, using criminal-court conviction records. Results Official adult-onset offenders were 14% of men, and 32% of convicted men, but accounted for only 15% of convictions. As anticipated by developmental theories emphasizing early-life influences on crime, adult-onset offenders’ histories of antisocial behavior spanned back to childhood. Relative to juvenile-offenders, during adolescence they had fewer delinquent peers and were more socially inhibited, which may have protected them from conviction. As anticipated by theories emphasizing the importance of situational influences on offending, adult-onset offenders, relative to non-offenders, during adulthood more often had schizophrenia, bipolar disorder, and alcohol-dependence, had weaker social bonds, anticipated fewer informal sanctions, and self-reported more offenses. Contrary to some expectations, adult-onset offenders did not have high IQ or high socioeconomic-status families protecting them from juvenile conviction. Conclusions A tailored theory for adult-onset offenders is unwarranted because few people begin crime de novo as adults. Official adult-onset offenders fall on a continuum of crime and its correlates, between official non-offenders and official juvenile-onset offenders. Existing theories can accommodate adult-onset offenders. PMID:27134318

Treating an Established Episode of Delirium in Palliative Care: Expert Opinion and Review of the Current Evidence Base With Recommendations for Future Development

PubMed Central

Pereira, José L.; Davis, Daniel H.J.; Currow, David C.; Meagher, David; Rabheru, Kiran; Wright, David; Bruera, Eduardo; Hartwick, Michael; Gagnon, Pierre R.; Gagnon, Bruno; Breitbart, William; Regnier, Laura; Lawlor, Peter G.

2014-01-01

Context Delirium is a highly prevalent complication in patients in palliative care settings, especially in the end-of-life context. Objectives To review the current evidence base for treating episodes of delirium in palliative care settings and propose a framework for future development. Methods We combined multidisciplinary input from delirium researchers and other purposely selected stakeholders at an international delirium study planning meeting. This was supplemented by a literature search of multiple databases and relevant reference lists to identify studies regarding therapeutic interventions for delirium. Results The context of delirium management in palliative care is highly variable. The standard management of a delirium episode includes the investigation of precipitating and aggravating factors followed by symptomatic treatment with drug therapy. However, the intensity of this management depends on illness trajectory and goals of care in addition to the local availability of both investigative modalities and therapeutic interventions. Pharmacologically, haloperidol remains the practice standard by consensus for symptomatic control. Dosing schedules are derived from expert opinion and various clinical practice guidelines as evidence-based data from palliative care settings are limited. The commonly used pharmacologic interventions for delirium in this population warrant evaluation in clinical trials to examine dosing and titration regimens, different routes of administration, and safety and efficacy compared with placebo. Conclusion Delirium treatment is multidimensional and includes the identification of precipitating and aggravating factors. For symptomatic management, haloperidol remains the practice standard. Further high-quality collaborative research investigating the appropriate treatment of this complex syndrome is needed. PMID:24480529

Future Perfect?: Teachers' Expectations and Explanations of Their Latino Immigrant Students' Postsecondary Futures

ERIC Educational Resources Information Center

Dabach, Dafney Blanca; Suárez-Orozco, Carola; Hernandez, Sera J.; Brooks, Maneka Deanna

2018-01-01

Teacher expectancy research has demonstrated the greatest effects for members of racialized groups. Most research has focused on students' near-term abilities; missing are understandings of how teachers perceive their students' future trajectories. Drawing on social mirroring and attribution theories, this study investigates how 14 elementary,…

High-fertility phenotypes: two outbred mouse models exhibit substantially different molecular and physiological strategies warranting improved fertility.

PubMed

Langhammer, Martina; Michaelis, Marten; Hoeflich, Andreas; Sobczak, Alexander; Schoen, Jennifer; Weitzel, Joachim M

2014-01-01

Animal models are valuable tools in fertility research. Worldwide, there are more than 400 transgenic or knockout mouse models available showing a reproductive phenotype; almost all of them exhibit an infertile or at least subfertile phenotype. By contrast, animal models revealing an improved fertility phenotype are barely described. This article summarizes data on two outbred mouse models exhibiting a 'high-fertility' phenotype. These mouse lines were generated via selection over a time period of more than 40 years and 161 generations. During this selection period, the number of offspring per litter and the total birth weight of the entire litter nearly doubled. Concomitantly with the increased fertility phenotype, several endocrine parameters (e.g. serum testosterone concentrations in male animals), physiological parameters (e.g. body weight, accelerated puberty, and life expectancy), and behavioral parameters (e.g. behavior in an open field and endurance fitness on a treadmill) were altered. We demonstrate that the two independently bred high-fertility mouse lines warranted their improved fertility phenotype using different molecular and physiological strategies. The fertility lines display female- as well as male-specific characteristics. These genetically heterogeneous mouse models provide new insights into molecular and cellular mechanisms that enhance fertility. In view of decreasing fertility in men, these models will therefore be a precious information source for human reproductive medicine. Translated abstract A German translation of abstract is freely available at http://www.reproduction-online.org/content/147/4/427/suppl/DC1.

Development of a Linear Ion Trap Mass Spectrometer (LITMS) Investigation for Future Planetary Surface Missions

NASA Technical Reports Server (NTRS)

Brinckerhoff, W.; Danell, R.; Van Ameron, F.; Pinnick, V.; Li, X.; Arevalo, R.; Glavin, D.; Getty, S.; Mahaffy, P.; Chu, P.;

Renewable Electricity Futures Study. Volume 2. Renewable Electricity Generation and Storage Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Augustine, Chad; Bain, Richard; Chapman, Jamie

2012-06-15

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%–90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT). Learn more at the RE Futures website. http://www.nrel.gov/analysis/re_futures/« less

Renewable Electricity Futures Study. Volume 2: Renewable Electricity Generation and Storage Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Augustine, C.; Bain, R.; Chapman, J.

2012-06-01

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%-90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT).« less

Developing Present-day Proxy Cases Based on NARVAL Data for Investigating Low Level Cloud Responses to Future Climate Change.

NASA Astrophysics Data System (ADS)

Reilly, Stephanie

2017-04-01

The energy budget of the entire global climate is significantly influenced by the presence of boundary layer clouds. The main aim of the High Definition Clouds and Precipitation for Advancing Climate Prediction (HD(CP)2) project is to improve climate model predictions by means of process studies of clouds and precipitation. This study makes use of observed elevated moisture layers as a proxy of future changes in tropospheric humidity. The associated impact on radiative transfer triggers fast responses in boundary layer clouds, providing a framework for investigating this phenomenon. The investigation will be carried out using data gathered during the Next-generation Aircraft Remote-sensing for VALidation (NARVAL) South campaigns. Observational data will be combined with ECMWF reanalysis data to derive the large scale forcings for the Large Eddy Simulations (LES). Simulations will be generated for a range of elevated moisture layers, spanning a multi-dimensional phase space in depth, amplitude, elevation, and cloudiness. The NARVAL locations will function as anchor-points. The results of the large eddy simulations and the observations will be studied and compared in an attempt to determine how simulated boundary layer clouds react to changes in radiative transfer from the free troposphere. Preliminary LES results will be presented and discussed.

Deciding for Future Selves Reduces Loss Aversion

PubMed Central

Cheng, Qiqi; He, Guibing

2017-01-01

In this paper, we present an incentivized experiment to investigate the degree of loss aversion when people make decisions for their current selves and future selves under risk. We find that when participants make decisions for their future selves, they are less loss averse compared to when they make decisions for their current selves. This finding is consistent with the interpretation of loss aversion as a bias in decision-making driven by emotions, which are reduced when making decisions for future selves. Our findings endorsed the external validity of previous studies on the impact of emotion on loss aversion in a real world decision-making environment. PMID:28979234

Deciding for Future Selves Reduces Loss Aversion.

PubMed

Cheng, Qiqi; He, Guibing

2017-01-01

In this paper, we present an incentivized experiment to investigate the degree of loss aversion when people make decisions for their current selves and future selves under risk. We find that when participants make decisions for their future selves, they are less loss averse compared to when they make decisions for their current selves. This finding is consistent with the interpretation of loss aversion as a bias in decision-making driven by emotions, which are reduced when making decisions for future selves. Our findings endorsed the external validity of previous studies on the impact of emotion on loss aversion in a real world decision-making environment.

The development of future-oriented control: an electrophysiological investigation.

PubMed

Waxer, Matthew; Morton, J Bruce

2011-06-01

Cognitive control, or the ability to focus attention and select task-appropriate responses, is not static but can be dynamically adjusted in the face of changing environmental circumstances. Several models suggest a role for conflict-monitoring in triggering these adjustments, whereby instances of response uncertainty are detected by the anterior cingulate cortex and strengthen attention-guiding rules actively maintained by lateral prefrontal cortex. Given the continued development of active maintenance mechanisms into adolescence, these models predict that the capacity to dynamically modulate control should be protracted in its development. The present study tested this prediction by examining age-related differences in behavioral and electrophysiological adaptations to prior conflict. Children, adolescents, and adults were administered the Dimensional Change Card Sort (DCCS; Zelazo, 2006) - a developmentally-appropriate task modified so that response conflict varied from trial to trial - as cortical activity was measured by means of event-related potentials (ERPs). Although all groups showed a robust conflict effect, there were pronounced age-related differences in behavioral and electrophysiological adaptations to prior conflict. First, responses to incongruent trials were faster following incongruent trials than following congruent trials, but only for adults and adolescents. Second, ERP components that indexed response conflict, and the cortical source of these components, were modulated by preceding conflict for adults and adolescents, but not children. Taken together, the findings suggest that adults and adolescents take advantage of prior conflict to prepare for the future, whereas children respond to cognitive challenges as they occur. Theoretical implications are discussed. Copyright © 2011 Elsevier Inc. All rights reserved.

Investigation of very high energy rockets for future SSTO vehicles

NASA Astrophysics Data System (ADS)

Froning, H. D., Jr.

1989-04-01

Several new propulsion possibilities are being explored in the U.S.A. which might significantly increase the amount of payload that can be propelled into orbit for a given launch vehicle weight. As such, they might enable significant reduction in the future cost of transportation between earth and space. One possibility is the combustion of matter that is in an excited atomic or molecular state. Another possibility is the annihilation of matter by means of anti-matter (by matter with identical mass and opposite electrical charge). And if an appreciable fraction of the energies released by either of these processes could be converted into the useful kinetic energy of a rocket's exhaust, a 2-6-fold increase in its specific impulse might be achieved. This paper shows that a 2-6-fold increase in rocket specific impulse might enable a 4-12-fold reduction in aerospace vehicle weight. It also shows that the specific impulse potential of excited matter or anti-matter fuels might enable transport of heavy payloads into earth orbit by means of single-stage-to-orbit vehicles that would be no heavier than current commercial airline jets.

Future generations, environmental ethics, and global environmental change

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tonn, B.E.

1994-12-31

The elements of a methodology to be employed by the global community to investigate the consequences of global environmental change upon future generations and global ecosystems are outlined in this paper. The methodology is comprised of two major components: A possible future worlds model; and a formal, citizen-oriented process to judge whether the possible future worlds potentially inheritable by future generations meet obligational standards. A broad array of descriptors of future worlds can be encompassed within this framework, including survival of ecosystems and other species and satisfaction of human concerns. The methodology expresses fundamental psychological motivations and human myths journey,more » renewal, mother earth, and being-in-nature-and incorporates several viewpoints on obligations to future generations-maintaining options, fairness, humility, and the cause of humanity. The methodology overcomes several severe drawbacks of the economic-based methods most commonly used for global environmental policy analysis.« less

Cancer Cluster Investigations: Review of the Past and Proposals for the Future

PubMed Central

Goodman, Michael; LaKind, Judy S.; Fagliano, Jerald A.; Lash, Timothy L.; Wiemels, Joseph L.; Winn, Deborah M.; Patel, Chirag; Van Eenwyk, Juliet; Kohler, Betsy A.; Schisterman, Enrique F.; Albert, Paul; Mattison, Donald R.

2014-01-01

Residential clusters of non-communicable diseases are a source of enduring public concern, and at times, controversy. Many clusters reported to public health agencies by concerned citizens are accompanied by expectations that investigations will uncover a cause of disease. While goals, methods and conclusions of cluster studies are debated in the scientific literature and popular press, investigations of reported residential clusters rarely provide definitive answers about disease etiology. Further, it is inherently difficult to study a cluster for diseases with complex etiology and long latency (e.g., most cancers). Regardless, cluster investigations remain an important function of local, state and federal public health agencies. Challenges limiting the ability of cluster investigations to uncover causes for disease include the need to consider long latency, low statistical power of most analyses, uncertain definitions of cluster boundaries and population of interest, and in- and out-migration. A multi-disciplinary Workshop was held to discuss innovative and/or under-explored approaches to investigate cancer clusters. Several potentially fruitful paths forward are described, including modern methods of reconstructing residential history, improved approaches to analyzing spatial data, improved utilization of electronic data sources, advances using biomarkers of carcinogenesis, novel concepts for grouping cases, investigations of infectious etiology of cancer, and “omics” approaches. PMID:24477211

When the future becomes the past: Differences in brain activation patterns for episodic memory and episodic future thinking.

PubMed

Weiler, Julia A; Suchan, Boris; Daum, Irene

2010-10-15

Episodic memory and episodic future thinking activate a network of overlapping brain regions, but little is known about the mechanism with which the brain separates the two processes. It was recently suggested that differential activity for memory and future thinking may be linked to differences in the phenomenal properties (e.g., richness of detail). Using functional magnetic resonance imaging in healthy subjects and a novel experimental design, we investigated the networks involved in the imagery of future and the recall of past events for the same target occasion, i.e. the Christmas and New Year's holidays, thereby keeping temporal distance and content similar across conditions. Although ratings of phenomenal characteristics were comparable for future thoughts and memories, differential activation patterns emerged. The right posterior hippocampus exhibited stronger memory-related activity during early event recall, and stronger future thought-related activity during late event imagination. Other regions, e.g., the precuneus and lateral prefrontal cortex, showed the reverse activation pattern with early future-associated and late past-associated activation. Memories compared to future thoughts were further related to stronger activation in several visual processing regions, which accords with a reactivation of the original perceptual experience. In conclusion, the results showed for the first time unique neural signatures for both memory and future thinking even in the absence of differences in phenomenal properties and suggested different time courses of brain activation for episodic memory and future thinking. Copyright 2010 Elsevier B.V. All rights reserved.

Measuring the Effect of Housing Quality Interventions: The Case of the New Zealand “Rental Warrant of Fitness”

PubMed Central

Telfar-Barnard, Lucy; Bennett, Julie; Howden-Chapman, Philippa; Jacobs, David E.; Ormandy, David; Cutler-Welsh, Matthew; Preval, Nicholas; Baker, Michael G.; Keall, Michael

2017-01-01

In New Zealand, as in many other countries, housing in the private-rental sector is in worse condition than in the owner-occupier housing sector. New Zealand residential buildings have no inspection regime after original construction signoff. Laws and regulations mandating standards for existing residential housing are outdated and spread over a range of instruments. Policies to improve standards in existing housing have been notoriously difficult to implement. In this methods paper, we describe the development and implementation of a rental Warrant of Fitness (WoF) intended to address these problems. Dwellings must pass each of 29 criteria for habitability, insulation, heating, ventilation, safety, amenities, and basic structural soundness to reach the WoF minimum standard. The WoF’s development was based on two decades of research on the impact of housing quality on health and wellbeing, and strongly influenced by the UK Housing Health and Safety Rating System and US federal government housing standards. Criteria were field-tested across a range of dwelling types and sizes, cities, and climate zones. The implementation stage of our WoF research consists of a non-random controlled quasi-experimental study in which we work with two city-level local government councils to implement the rental WoF, recruiting adjoining council areas as controls, and measuring changes in health, economic, and social outcomes. PMID:29112147

Fidelity in Models-Based Practice Research in Sport Pedagogy: A Guide for Future Investigations

ERIC Educational Resources Information Center

Hastie, Peter A.; Casey, Ashley

2014-01-01

This paper provides a commentary on research on models-based practice within physical education and presents a tutorial that aims to guide the reporting of future research using pedagogical models. Three key elements are presented that could be considered as essential for inclusion in any methods section in order for readers to gain an accurate…

Predictions of future ephemeral springtime waterbird stopover habitat availability under global change

USGS Publications Warehouse

Uden, Daniel R.; Allen, Craig R.; Bishop, Andrew A.; Grosse, Roger; Jorgensen, Christopher F.; LaGrange, Theodore G.; Stutheit, Randy G.; Vrtiska, Mark P.

2015-01-01

In the present period of rapid, worldwide change in climate and landuse (i.e., global change), successful biodiversity conservation warrants proactive management responses, especially for long-distance migratory species. However, the development and implementation of management strategies can be impeded by high levels of uncertainty and low levels of control over potentially impactful future events and their effects. Scenario planning and modeling are useful tools for expanding perspectives and informing decisions under these conditions. We coupled scenario planning and statistical modeling to explain and predict playa wetland inundation (i.e., presence/absence of water) and ponded area (i.e., extent of water) in the Rainwater Basin, an anthropogenically altered landscape that provides critical stopover habitat for migratory waterbirds. Inundation and ponded area models for total wetlands, those embedded in rowcrop fields, and those not embedded in rowcrop fields were trained and tested with wetland ponding data from 2004 and 2006–2009, and then used to make additional predictions under two alternative climate change scenarios for the year 2050, yielding a total of six predictive models and 18 prediction sets. Model performance ranged from moderate to good, with inundation models outperforming ponded area models, and models for non-rowcrop-embedded wetlands outperforming models for total wetlands and rowcrop-embedded wetlands. Model predictions indicate that if the temperature and precipitation changes assumed under our climate change scenarios occur, wetland stopover habitat availability in the Rainwater Basin could decrease in the future. The results of this and similar studies could be aggregated to increase knowledge about the potential spatial and temporal distributions of future stopover habitat along migration corridors, and to develop and prioritize multi-scale management actions aimed at mitigating the detrimental effects of global change on migratory

Pediatric Orthopaedic Workforce in 2014: Current Workforce and Projections for the Future.

PubMed

Sawyer, Jeffrey R; Jones, Kerwyn C; Copley, Lawson A; Chambers, Stephanie

2017-01-01

The changing nature of the United States (US) health care system has prompted debate concerning the physician supply. The basic questions are: do we have an adequate number of surgeons to meet current demands and are we training the correct number of surgeons to meet future demands? The purpose of this analysis was to characterize the current pediatric orthopaedic workforce in terms of supply and demand, both present and future. Databases were searched (POSNA, SF Match, KID, MGMA) to determine the current pediatric orthopaedic workforce and workforce distribution, as well as pediatric orthopaedic demand. The number of active Pediatric Orthopaedic Society of North America (POSNA) members increased over the past 20 years, from 410 in 1993 to 653 in 2014 (155% increase); however, the density of POSNA members is not equally distributed, but correlates to population density. The number of estimated pediatric discharges, orthopaedic and nonorthopaedic, has remained relatively stable from 6,348,537 in 1997 to 5,850,184 in 2012. Between 2003 and 2013, the number of pediatric orthopaedic fellows graduating from Accreditation Council for Graduate Medical Education and non-Accreditation Council for Graduate Medical Education programs increased from 39 to 50 (29%), with a peak of 67 fellows (71%) in 2009. Although predicting the exact need for pediatric orthopaedic surgeons (POS) is impossible because of the complex interplay among macroeconomic, governmental, insurance, and local factors, some trends were identified: the supply of POS has increased, which may offset the expected numbers of experienced surgeons who will be leaving the workforce in the next 10 to 15 years; macroeconomic factors influencing demand for physician services, driven by gross domestic product and population growth, are expected to be stable in the near future; expansion of the scope of practice for POS is expected to continue; and further similar assessments are warranted. Level II-economic and

Characterization of terrestrial hydrothermal alteration products with Mars analog instrumentation: Implications for current and future rover investigations

NASA Astrophysics Data System (ADS)

Black, Sarah R.; Hynek, Brian M.

2018-06-01

host a wide range of microbial life here on Earth-are of high interest and it is likely that future rovers will encounter similar mineral assemblages. Therefore, future rovers would benefit from using a combination of these methods and expanding the VSWIR sampling range to the full 300-2500 nm to conduct a comprehensive mineralogical investigation.

Does the health status of intimate partner violence victims warrant pharmacies as portals for public health promotion?

PubMed

Cerulli, Catherine; Cerulli, Jennifer; Santos, Elizabeth J; Lu, Najii; He, Hua; Kaukeinen, Kimberly; White, Anne Marie; Tu, Xin

To explore whether the health status of intimate partner violence (IPV) victims warrants pharmacies to be portals for public health promotion. Specific objectives included (1) identifying prevalence of IPV including domestic violence (DV) and sexual assault (SA) in a community sample, (2) describing characteristics and correlates of DV/SA between participants who reported and did not report DV/SA, and (3) exploring whether DV/SA status is related to mental health medication use. Cross sectional. Upstate New York during 2006. English- and Spanish-speaking respondents younger than 65 years of age answering four questions to assess DV/SA. Secondary analysis of a countywide random telephone survey, the 2006 Monroe County Adult Health Survey, which collects prevalence data on health behaviors and health status indicators. To determine whether those reporting DV/SA are at increased odds for mental health medication use, controlling for other sociodemographic- and health-related variables. The survey response rate was 30.3%, with 1,881 respondents meeting inclusion criteria. Those reporting DV/SA were almost twice as likely to use mental health medications. However, when controlling for other variables, only poor mental and physical health were significant in increasing the odds of mental health medication use. The analyses reported here suggest that DV/SA victims in a community sample use mental health medications. When controlling for other variables, survey respondents reported worse physical and mental health. If pharmacies are suitable portals for DV/SA outreach, curricula would need to provide the knowledge and skills needed to take an active role in this public health promotion.

'Thinking ill of others without sufficient warrant?' Transcending the accuracy-inaccuracy dualism in prejudice and stereotyping research.

PubMed

Dixon, John

2017-03-01

Research on prejudice seeks to understand and transform inaccurate beliefs about others. Indeed, historically such research has offered a cautionary tale of the biased nature of human cognition. Recently, however, this view has been challenged by work defending the essential rationality of intergroup perception, a theme captured controversially in Jussim and colleagues' (2009) research on the 'unbearable accuracy of stereotyping'. The present paper argues that in its own terms the 'rationalist turn' in socio-cognitive research on stereotyping presents an important challenge to the prejudice tradition, raising troubling questions about its conceptual and empirical foundations. However, it also argues for the necessity of transcending those terms. By focusing on the correspondence between individual beliefs and the supposedly 'objective' characteristics of others, we neglect the historical and discursive practices through which the social realities that we 'perceive' are actively constructed and institutionalized. We mask their social origins, contested and perspectival nature, relativity, and relationship to wider structures of power. By implication, moving beyond the Allportian perspective that has dominated both the prejudice tradition and the emerging stereotype accuracy paradigm, we may now need to prioritize other kinds of questions. Reversing Allport's famous definition of prejudice, it may now be time to ask: How, and with what consequences, does 'thinking ill of others' become sufficiently warranted? How does such thinking become part of institutionalized relations of power and an accepted way of perceiving, evaluating and treating others? What should social psychologists be doing to challenge this state of affairs? © 2017 The British Psychological Society.

Physical and Mental Health Trajectories of Cancer Patients and Caregivers Across the Year Post-Diagnosis: A Dyadic Investigation

PubMed Central

Shaffer, Kelly M.; Kim, Youngmee; Carver, Charles S.

2016-01-01

Objective Evidence suggests interdependence between cancer patients’ and their caregivers’ physical and mental health. However, the extent to which caregivers’ health relates to their patients’ recovery, or patients’ health affects their caregivers’ outcomes, is largely unknown. This dyadic investigation reports the relations between cancer patients’ and their caregivers’ physical and mental health trajectories during the year following diagnosis. Design Ninety-two colorectal cancer patient-caregiver dyads completed questionnaires at two, six, and twelve months post-diagnosis. Outcome Measures Self-reported physical and mental health using the Medical Outcomes Study Short Form Health Survey-12. Results Patients reported improved physical health over the year following their diagnosis, whereas caregivers reported declining physical health. Patients with lower mental health at diagnosis had stagnated physical health recovery. Caregivers’ physical health declined most noticeably among those reporting low mental health at diagnosis and whose patients reported low physical health at diagnosis. Conclusion Findings suggest targeting health interventions to cancer patients and caregivers reporting poor mental health at diagnosis may mitigate their long-term physical morbidity. Limited evidence of dyadic interdependence between patients’ and caregivers’ physical and mental health trajectories suggests future studies are warranted to identify psychosocial and medical characteristics moderating the relations between patients’ and caregivers’ health. PMID:26680247

Affective bias and current, past and future adolescent depression: a familial high risk study.

PubMed

Kilford, Emma J; Foulkes, Lucy; Potter, Robert; Collishaw, Stephan; Thapar, Anita; Rice, Frances

2015-03-15

Affective bias is a common feature of depressive disorder. However, a lack of longitudinal studies means that the temporal relationship between affective bias and depression is not well understood. One group where studies of affective bias may be particularly warranted is the adolescent offspring of depressed parents, given observations of high rates of depression and a severe and impairing course of disorder in this group. A two wave panel design was used in which adolescent offspring of parents with recurrent depression completed a behavioural task assessing affective bias (The Affective Go/No Go Task) and a psychiatric interview. The affective processing of adolescents with current, prior and future depressive disorder was compared to that of adolescents free from disorder. Adolescents with current depression and those who developed depression at follow-up made more commission errors for sad than happy targets compared to adolescents free from disorder. There was no effect of prior depression on later affective processing. Small cell sizes meant we were unable to separately compare those with new onset and recurrent depressive disorder. Valence-specific errors in behavioural inhibition index future vulnerability to depression in adolescents already at increased risk and may represent a measure of affective control. Currently depressed adolescents show a similar pattern of affective bias or deficits in affective control. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

Affective bias and current, past and future adolescent depression: A familial high risk study

PubMed Central

Kilford, Emma J.; Foulkes, Lucy; Potter, Robert; Collishaw, Stephan; Thapar, Anita; Rice, Frances

2015-01-01

Background Affective bias is a common feature of depressive disorder. However, a lack of longitudinal studies means that the temporal relationship between affective bias and depression is not well understood. One group where studies of affective bias may be particularly warranted is the adolescent offspring of depressed parents, given observations of high rates of depression and a severe and impairing course of disorder in this group. Methods A two wave panel design was used in which adolescent offspring of parents with recurrent depression completed a behavioural task assessing affective bias (The Affective Go/No Go Task) and a psychiatric interview. The affective processing of adolescents with current, prior and future depressive disorder was compared to that of adolescents free from disorder. Results Adolescents with current depression and those who developed depression at follow-up made more commission errors for sad than happy targets compared to adolescents free from disorder. There was no effect of prior depression on later affective processing. Limitations Small cell sizes meant we were unable to separately compare those with new onset and recurrent depressive disorder. Conclusions Valence-specific errors in behavioural inhibition index future vulnerability to depression in adolescents already at increased risk and may represent a measure of affective control. Currently depressed adolescents show a similar pattern of affective bias or deficits in affective control. PMID:25527997

Long-term care financing: options for the future.

PubMed

Mulvey, Janemarie; Li, Annelise

2002-01-01

The aging of the baby boomers will have an enormous impact on the future of long-term care costs. This article projects the magnitude of that impact, discusses sources of financing, and considers the cost and feasibility of three options for financing future long-term care services. The authors investigate the alternatives of increasing personal savings, raising payroll taxes and expanding employer-sponsored private long-term care insurance coverage, respectively.

17 CFR 8.07 - Investigation reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Section 8.07 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXCHANGE PROCEDURES FOR DISCIPLINARY, SUMMARY, AND MEMBERSHIP DENIAL ACTIONS Disciplinary Procedure § 8.07 Investigation reports. (a) The enforcement staff shall submit a written investigation report to the disciplinary...

Resolving future fire management conflicts using multicriteria decision making.

PubMed

Driscoll, Don A; Bode, Michael; Bradstock, Ross A; Keith, David A; Penman, Trent D; Price, Owen F

2016-02-01

Management strategies to reduce the risks to human life and property from wildfire commonly involve burning native vegetation. However, planned burning can conflict with other societal objectives such as human health and biodiversity conservation. These conflicts are likely to intensify as fire regimes change under future climates and as growing human populations encroach farther into fire-prone ecosystems. Decisions about managing fire risks are therefore complex and warrant more sophisticated approaches than are typically used. We applied a multicriteria decision making approach (MCDA) with the potential to improve fire management outcomes to the case of a highly populated, biodiverse, and flammable wildland-urban interface. We considered the effects of 22 planned burning options on 8 objectives: house protection, maximizing water quality, minimizing carbon emissions and impacts on human health, and minimizing declines of 5 distinct species types. The MCDA identified a small number of management options (burning forest adjacent to houses) that performed well for most objectives, but not for one species type (arboreal mammal) or for water quality. Although MCDA made the conflict between objectives explicit, resolution of the problem depended on the weighting assigned to each objective. Additive weighting of criteria traded off the arboreal mammal and water quality objectives for other objectives. Multiplicative weighting identified scenarios that avoided poor outcomes for any objective, which is important for avoiding potentially irreversible biodiversity losses. To distinguish reliably among management options, future work should focus on reducing uncertainty in outcomes across a range of objectives. Considering management actions that have more predictable outcomes than landscape fuel management will be important. We found that, where data were adequate, an MCDA can support decision making in the complex and often conflicted area of fire management. © 2015

Investigating children's spiritual experiences through the Health and Physical Education (HPE) learning area in Australian schools.

PubMed

Lynch, Timothy

2015-02-01

The purpose of this study is to explore spirituality within the Health and Physical Education (HPE) learning area, through investigating children's experiences within three Brisbane Catholic Education primary schools (Queensland, Australia). There are seven dimensions of wellness: physical, intellectual, emotional, social, spiritual, environmental, and occupational, which are all strongly connected (Robbins et al. in A wellness way of life, 9th edition, McGraw Hill, USA, 2011). It is logical that HPE, which promotes students to adopt lifelong health and well-being, offers opportunities for spirituality to be experienced and warrants investigation. Data gathered in this qualitative research suggest that regular quality inclusive HPE lessons increased students' potential for spiritual experiences.

Phenomenology of future-oriented mind-wandering episodes

PubMed Central

Stawarczyk, David; Cassol, Helena; D'Argembeau, Arnaud

2013-01-01

Recent research suggests that prospective and non-prospective forms of mind-wandering possess distinct properties, yet little is known about what exactly differentiates between future-oriented and non-future-oriented mind-wandering episodes. In the present study, we used multilevel exploratory factor analyses (MEFA) to examine the factorial structure of various phenomenological dimensions of mind-wandering, and we then investigated whether future-oriented mind-wandering episodes differ from other classes of mind-wandering along the identified factors. We found that the phenomenological dimensions of mind-wandering are structured in four factors: representational format (inner speech vs. visual imagery), personal relevance, realism/concreteness, and structuration. Prospective mind-wandering differed from non-prospective mind-wandering along each of these factors. Specifically, future-oriented mind-wandering episodes involved inner speech to a greater extent, were more personally relevant, more realistic/concrete, and more often part of structured sequences of thoughts. These results show that future-oriented mind-wandering possesses a unique phenomenological signature and provide new insights into how this particular form of mind-wandering may adaptively contribute to autobiographical planning. PMID:23882236

Intermittent hypoxia, respiratory plasticity and sleep apnea in humans: present knowledge and future investigations.

PubMed

Mateika, Jason H; Syed, Ziauddin

2013-09-15

This review examines the role that respiratory plasticity has in the maintenance of breathing stability during sleep in individuals with sleep apnea. The initial portion of the review considers the manner in which repetitive breathing events may be initiated in individuals with sleep apnea. Thereafter, the role that two forms of respiratory plasticity, progressive augmentation of the hypoxic ventilatory response and long-term facilitation of upper airway and respiratory muscle activity, might have in modifying breathing events in humans is examined. In this context, present knowledge regarding the initiation of respiratory plasticity in humans during wakefulness and sleep is addressed. Also, published findings which reveal that exposure to intermittent hypoxia promotes breathing instability, at least in part, because of progressive augmentation of the hypoxic ventilatory response and the absence of long-term facilitation, are considered. Next, future directions are presented and are focused on the manner in which forms of plasticity that stabilize breathing might be promoted while diminishing destabilizing forms, concurrently. These future directions will consider the potential role of circadian rhythms in the promotion of respiratory plasticity and the role of respiratory plasticity in enhancing established treatments for sleep apnea. Published by Elsevier B.V.

Parental Warmth and Risks of Substance Use in Children with Attention-Deficit/Hyperactivity Disorder: Findings from a 10-12 Year Longitudinal Investigation.

PubMed

Tandon, Mini; Tillman, Rebecca; Spitznagel, Edward; Luby, Joan

2014-06-01

The study examined factors in the risk trajectory for Substance Use Disorder (SUD) over a 10-12 year period in children with ADHD. N=145 children between the ages of 7 and 16 with ADHD and healthy controls were assessed every 2 years for 10-12 years as part of a larger, longitudinal investigation. Onset of substance use disorder was examined using Cox proportional hazards modeling, and included child and parent psychopathology, and parental warmth as well as other key factors. Low paternal warmth and maternal SUD were predictors of SUD in n=59 ADHD participants after adjusting for gender, child ODD, paternal SUD, maternal/paternal ADHD, maternal/paternal major depressive disorder (MDD), maternal/paternal anxiety, and low maternal warmth in the Cox model. Longitudinal study findings suggest that in addition to the established risk of ADHD and maternal SUD in development of child SUD, low paternal warmth is also associated with onset of SUD. This was evident after controlling for pertinent parent and child psychopathology. These findings suggest that paternal warmth warrants further investigation as a key target for novel interventions to prevent SUD in children with ADHD. More focused investigations examining paternal parenting factors in addition to parent and child psychopathology in the risk trajectory from ADHD to SUD are now warranted.

What Could Be Future Scenarios?—Lessons from the History of Public Health Surveillance for the Future

PubMed Central

Choi, Bernard C.K.

2015-01-01

This article provides insights into the future based on a review of the past and present of public health surveillance—the ongoing systematic collection, analysis, interpretation, and dissemination of health data for the planning, implementation, and evaluation of public health action. Public health surveillance dates back to the first recorded epidemic in 3180 BC in Egypt. A number of lessons and items of interest are summarised from a review of historical perspectives in the past 5,000 years and the current practice of surveillance. Some future scenarios are presented: exploring new frontiers; enhancing computer technology; improving epidemic investigations; improving data collection, analysis, dissemination and use; building on lessons from the past; building capacity; and enhancing global surveillance. It is concluded that learning from the past, reflecting on the present, and planning for the future can further enhance public health surveillance. PMID:29546093

Episodic future thinking reduces temporal discounting in healthy adolescents.

PubMed

Bromberg, Uli; Lobatcheva, Maria; Peters, Jan

2017-01-01

Episodic Future Thinking has proven efficient in reducing impulsive behavior in several adult populations. Whether it also has a beneficial impact on decision making in adolescents is not known. Here the impact of episodic future thinking on discounting behavior was investigated in a sample of healthy adolescents (n = 44, age range 13-16 years). Discounting behavior in trials including episodic future thinking was significantly less impulsive than in control trials (t = 2.74, p = .009, dz = .44). In a subsample we controlled for executive function, alcohol use and developmental measures. Neither executive function nor alcohol use but developmental measures explained variability in the effect of episodic future thinking. These findings reveal that episodic future thinking can improve adolescent decision making while the effect is to some degree modulated by developmental measures.

Early Childhood Sexuality Education: Future Educators' Attitudes and Considerations

ERIC Educational Resources Information Center

Brouskeli, Vasiliki; Sapountzis, Antonis

2017-01-01

Sexuality education is one of the most disputable health education programs as far as its inclusion in Early Childhood Education is concerned. This study was conducted in order to investigate early childhood future educators' attitudes and considerations about introducing sexuality education to their future pupils. We used a qualitative research…

Investigating Future Climate Scenarios

ERIC Educational Resources Information Center

Dempsey, Chris; Bodzin, Alec; Anastasio, David; Sahagian, Dork; Cirucci, Lori

2012-01-01

One of the most alarming impacts of projected climate change is a significant rise in sea level. Sea level has varied by hundreds of meters over geologic time, yet these changes have generally been slow paced, allowing ecosystems to adjust to changing land surface and marine habitats. Since the Industrial Revolution, anthropogenic emissions have…

Addressing Future Epidemics: Historical Human Rights Lessons from the AIDS Pandemic: Understanding human rights lessons from the early AIDS pandemic can aid policy makers in addressing future epidemics of infectious diseases.

PubMed

Mehta, Ambar; Quinn, Thomas C

The Ebola epidemic in West Africa sparked many ethical and polarizing public health questions on how to adequately control transmission of the virus. These deliberations had and will continue to influence patients, healthcare workers, public perceptions of disease, and governmental responses. Such extensive and potential ramifications warranted an analysis of prior epidemics to sufficiently inform policy makers and prepare them and other authorities for future epidemics. We analyzed how the general public, medical institutions, federal government, and patients themselves responded during the early stages of the AIDS pandemic in two different countries and cultures, the United States and India. Our analysis identified four key findings pertaining to the human rights of patients and healthcare workers and to the crucial roles of the government and medical community. The first demands that authoritative officials acknowledge the presence of high-risk behaviors and properly educate the public without stigmatizing groups of individuals. For this task, the medical community and federal government must form and display to the public a respectful and collaborative partnership towards battling the epidemic. These two synergistic endeavors will then allow appropriate officials to implement effective, yet civil, interventions for limiting transmission. Finally, the same officials must ensure that their interventions maintain the human rights of high-risk populations and of healthcare workers. Applying these findings to future epidemics of infectious diseases can aid policy makers in navigating complicated ethical and public health questions, and help prevent them from repeating past mistakes in handling epidemics.

Of Leisure: Education for the Future.

ERIC Educational Resources Information Center

Rumstein, Regina

The investigation focused on college students' conception of leisure in the future, particularly their viewpoint about (1) availability of leisure time, (2) role of society relative leisure and (3) use of leisure time. A total of 90 undergraduate college students responded to a questionnaire specially designed for this study. Data indicate…

Future methane emissions from animals

NASA Astrophysics Data System (ADS)

Anastasi, C.; Simpson, V. J.

1993-04-01

The future global emission of CH4 from enteric fermentation in animals has been estimated for cattle, sheep, and buffalo, which together contribute approximately 91% of the total CH4 emitted from domesticated animals at present. A simple model has been used to relate livestock levels to the national human populations for each country involved in breeding the three species included in this analysis. United Nations population predictions to 2025 were then included in the model to estimate future CH4 emissions. A variational analysis was carried out to investigate the effect of future changes in both the land available for grazing and the nutritional content of feedstocks. Results suggest that the total emission of CH4 from enteric fermentation in domestic animals will increase from 84 Tg CH4 per year (Tg = 1012 g) in 1990 to 119 (±12) Tg CH4 yr-1 by 2025. These values correspond to an average rate of increase over the next 35 years of 1.0 Tg CH4 yr-1.

Quantitative comparison of cognitive behavioral therapy and music therapy research: a methodological best-practices analysis to guide future investigation for adult psychiatric patients.

PubMed

Silverman, Michael J

2008-01-01

components for existing quantitative psychiatric music therapy research with adult consumers, thus highlighting potential areas and elements for future investigations. A second table depicts a number of potential dependent measures and their sources to be evaluated in future music therapy studies. A third table providing suggestions for future research is derived from a synthesis of the tables and is included to guide researchers and encourage the advancement and expansion of the current literature base. The body of the paper is a discussion of the results of the literature analysis derived from the tables, meta-analyses, and reviews of literature. It is hoped that this report will lead to the addition of future high-quality quantitative research to the psychiatric music therapy literature base and thus provide evidence-based services to as many persons with mental illnesses as possible.

Dismantling the present and future threats of testicular cancer: a grounded theory of positive and negative adjustment trajectories.

PubMed

Matheson, Lauren; Boulton, Mary; Lavender, Verna; Protheroe, Andrew; Brand, Sue; Wanat, Marta; Watson, Eila

2016-02-01

Testicular cancer commonly affects men in the prime of their lives. While survival rates are excellent, little previous research has examined men's experiences of adjustment to survivorship. We aimed to explore this issue in younger testicular cancer survivors. In-depth qualitative interviews were conducted with testicular cancer survivors over two time points approximately 6 months apart in the year following treatment completion. Interviews were analysed using a grounded theory approach. The sample included 18 testicular cancer survivors between 22 and 44 years (mean age 34). A grounded theory was developed, which explained the process of positive adjustment over the first year following the treatment completion in terms of men's ability to dismantle the present and future threats of cancer, involving the key transitions of gaining a sense of perspective and striving to get on with life and restore normality. These were facilitated by six key processes. The processes that explained a negative adjustment trajectory are also presented. These findings contribute to the understanding of the psychosocial impact of testicular cancer on younger men's lives and have implications for the provision of support to testicular cancer survivors. Further investigation into the feasibility of one-on-one peer support interventions is warranted, as well as informal support that respects men's desire for independence. Understanding the processes involved in adjustment highlights ways in which health professionals can offer support to those struggling to adjust through challenging illness beliefs, encouraging emotional disclosure and facilitating peer mentoring.

Optimism for the Future in Younger and Older Adults.

PubMed

Durbin, Kelly A; Barber, Sarah J; Brown, Maddalena; Mather, Mara

2018-01-09

Research has suggested that older adults are less optimistic about their future than younger adults; however, a limitation of prior studies is that younger and older adults were forecasting to different ages and stages of life. To address this, we investigated whether there are age differences in future optimism when people project to the exact same age. We also tested whether optimism differs when projecting one's own future versus another person's future. Participants were 285 younger and 292 older adults recruited from Amazon Mechanical Turk. Participants completed writing and word-rating tasks in which they imagined their own future in 15 years, their own future at age 85, or the average person's future at age 85. Younger adults were more optimistic than older adults about their own future in 15 years. In contrast, both age groups were similarly optimistic about their future at age 85 and expected it to be more positive than others' future at age 85. Contrary to previous research, younger and older adults had comparable future forecasts when projecting to the exact same age. These findings emphasize the need to consider age and stage of life when examining age differences in future optimism. © The Author(s) 2018. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Emergency management of severe hyperkalemia: Guideline for best practice and opportunities for the future.

PubMed

Rossignol, Patrick; Legrand, Matthieu; Kosiborod, Mikhail; Hollenberg, Steven M; Peacock, W Frank; Emmett, Michael; Epstein, Murray; Kovesdy, Csaba P; Yilmaz, Mehmet Birhan; Stough, Wendy Gattis; Gayat, Etienne; Pitt, Bertram; Zannad, Faiez; Mebazaa, Alexandre

2016-11-01

Hyperkalemia is a common electrolyte disorder, especially in chronic kidney disease, diabetes mellitus, or heart failure. Hyperkalemia can lead to potentially fatal cardiac dysrhythmias, and it is associated with increased mortality. Determining whether emergency therapy is warranted is largely based on subjective clinical judgment. The Investigator Network Initiative Cardiovascular and Renal Clinical Trialists (INI-CRCT) aimed to evaluate the current knowledge pertaining to the emergency treatment of hyperkalemia. The INI-CRCT developed a treatment algorithm reflecting expert opinion of best practices in the context of current evidence, identified gaps in knowledge, and set priorities for future research. We searched PubMed (to August 4, 2015) for consensus guidelines, reviews, randomized clinical trials, and observational studies, limited to English language but not by publication date. Treatment approaches are based on small studies, anecdotal experience, and traditional practice patterns. The safety and real-world effectiveness of standard therapies remain unproven. Prospective research is needed and should include studies to better characterize the population, define the serum potassium thresholds where life-threatening arrhythmias are imminent, assess the potassium and electrocardiogram response to standard interventions. Randomized, controlled trials are needed to test the safety and efficacy of new potassium binders for the emergency treatment of severe hyperkalemia in hemodynamically stable patients. Existing emergency treatments for severe hyperkalemia are not supported by a compelling body of evidence, and they are used inconsistently across institutions, with potentially significant associated side effects. Further research is needed to fill knowledge gaps, and definitive clinical trials are needed to better define optimal management strategies, and ultimately to improve outcomes in these patients. Copyright © 2016 Elsevier Ltd. All rights reserved.

Warrant Officer Examinations. PR-4018

DTIC Science & Technology

1944-10-10

ccouunting, Administrative - Clcorica1, Judge, Advo Ge~nc. De~ptsAdxiiniistrati~ve 1 icl Adi isrtv - Supp:ly, generaile8 ~ Administrativo ’ - Supply, Air...chronological index if action in processing special and summary records of trial. Answers teleph.’nic inquirie’s pertaining to subject matter contain- ed...reproduction by lithopraphy, black and white process printing, and gelatin duplication; moy couidinnte and supervise procurement, storage, and distribution of

Games and (Preparation for Future) Learning

ERIC Educational Resources Information Center

Hammer, Jessica; Black, John

2009-01-01

What makes games effective for learning? The authors argue that games provide vicarious experiences for players, which then amplify the effects of future, formal learning. However, not every game succeeds in doing so! Understanding why some games succeed and others fail at this task means investigating both a given game's design and the…

Current and future contraceptive options for women living with HIV

PubMed Central

Patel, Rena C.; Bukusi, Elizabeth A.; Baeten, Jared M.

2018-01-01

Introduction Among women living with HIV, half of the pregnancies are unintended. Effective contraception can prevent unintended pregnancies and consequently reduce maternal mortality and perinatal transmission of HIV. While contraceptive options available for all women also apply to women living with HIV, specific considerations exist to the use of contraception by women living with HIV. Areas covered First, general principles guiding the use of contraception among women living with HIV are discussed, such as choice, method mix, relative effectiveness, and drug-drug interactions. Second, a detailed discussion of each contraceptive method and issues surrounding the use of that method, such as drug-drug interactions, follows. Third, future contraceptive options in advanced development for use by women or men are briefly discussed. Expert opinion Contraceptive methods available to all women should also be accessible to women living with HIV. When the relative effectiveness of a contraceptive method is reduced, for example due to drug-drug interactions with antiretrovirals, the method should still be made available to women living with HIV with the appropriate information sharing and counseling. Greater research on various aspects of contraceptive use by women living with HIV and more comprehensive testing of co-administration of hormonal contraceptives and common medications used by these women are warranted. PMID:28891343

Current and future contraceptive options for women living with HIV.

PubMed

Patel, Rena C; Bukusi, Elizabeth A; Baeten, Jared M

2018-01-01

Among women living with HIV, half of the pregnancies are unintended. Effective contraception can prevent unintended pregnancies and consequently reduce maternal mortality and perinatal transmission of HIV. While contraceptive options available for all women also apply to women living with HIV, specific considerations exist to the use of contraception by women living with HIV. Areas covered: First, general principles guiding the use of contraception among women living with HIV are discussed, such as choice, method mix, relative effectiveness, and drug-drug interactions. Second, a detailed discussion of each contraceptive method and issues surrounding the use of that method, such as drug-drug interactions, follows. Third, future contraceptive options in advanced development for use by women or men are briefly discussed. Expert opinion: Contraceptive methods available to all women should also be accessible to women living with HIV. When the relative effectiveness of a contraceptive method is reduced, for example due to drug-drug interactions with antiretrovirals, the method should still be made available to women living with HIV with the appropriate information sharing and counseling. Greater research on various aspects of contraceptive use by women living with HIV and more comprehensive testing of co-administration of hormonal contraceptives and common medications used by these women are warranted.

Renewable Electricity Futures Study. Volume 4: Bulk Electric Power Systems. Operations and Transmission Planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milligan, Michael; Ela, Erik; Hein, Jeff

2012-06-15

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%–90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT). Learn more at the RE Futures website. http://www.nrel.gov/analysis/re_futures/« less

Renewable Electricity Futures Study. Volume 4: Bulk Electric Power Systems: Operations and Transmission Planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milligan, M.; Ela, E.; Hein, J.

2012-06-01

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%-90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT).« less

Hepatoblastoma in children with Beckwith-Wiedemann syndrome: does it warrant different treatment?

PubMed

Trobaugh-Lotrario, Angela D; Venkatramani, Rajkumar; Feusner, James H

2014-07-01

Patients with Beckwith-Wiedemann Syndrome (BWS) are predisposed to developing hepatoblastoma. Clinical data were reviewed in all cases of hepatoblastoma in patients with BWS reported in the literature and from personal cases. Patients were identified by literature review using PubMed and by a search of the authors' local tumor registries. Fifty-six patients were identified. The median age of presentation with hepatoblastoma was 6 months (range birth-30 mo). Thirteen of 26 patients were born prematurely. Of 31 evaluable patients, 19 exhibited hemihypertrophy. Thirty-two of 33 patients with α-fetoprotein data reported had elevated levels at diagnosis. Overall survival was 75% (27 of 36 patients). Of 25 patients with data who survived, 24 were treated with chemotherapy and surgery (vs. only 2 of 8 who did not survive). All 9 patients with hepatoblastoma detected by routine screening with outcomes reported were surviving at the time of the reports. Overall survival was high in patients with BWS and hepatoblastoma, especially given lower stage at presentation and when treated with surgery and chemotherapy. Future prospective trials should evaluate if BWS is independently associated with outcome and if the outcome is improved by routine screening.

Characteristics of Early Work Experiences and Their Association with Future Employment

ERIC Educational Resources Information Center

McDonnall, Michele Capella; O'Mally, Jamie

2012-01-01

Introduction: Early work experiences are a key predictor of future employment for transition-age youths with visual impairments. We investigated how specific characteristics of early work experiences influence future employment and whether the receipt of Supplemental Security Income (SSI) benefits is associated with early work experiences among…

Application of forensic image analysis in accident investigations.

PubMed

Verolme, Ellen; Mieremet, Arjan

2017-09-01

Forensic investigations are primarily meant to obtain objective answers that can be used for criminal prosecution. Accident analyses are usually performed to learn from incidents and to prevent similar events from occurring in the future. Although the primary goal may be different, the steps in which information is gathered, interpreted and weighed are similar in both types of investigations, implying that forensic techniques can be of use in accident investigations as well. The use in accident investigations usually means that more information can be obtained from the available information than when used in criminal investigations, since the latter require a higher evidence level. In this paper, we demonstrate the applicability of forensic techniques for accident investigations by presenting a number of cases from one specific field of expertise: image analysis. With the rapid spread of digital devices and new media, a wealth of image material and other digital information has become available for accident investigators. We show that much information can be distilled from footage by using forensic image analysis techniques. These applications show that image analysis provides information that is crucial for obtaining the sequence of events and the two- and three-dimensional geometry of an accident. Since accident investigation focuses primarily on learning from accidents and prevention of future accidents, and less on the blame that is crucial for criminal investigations, the field of application of these forensic tools may be broader than would be the case in purely legal sense. This is an important notion for future accident investigations. Copyright © 2017 Elsevier B.V. All rights reserved.

A critical evaluation of the validity of episodic future thinking: A clinical neuropsychology perspective.

PubMed

Ward, Amanda M

2016-11-01

Episodic future thinking is defined as the ability to mentally simulate a future event. Although episodic future thinking has been studied extensively in neuroscience, this construct has not been explored in depth from the perspective of clinical neuropsychology. The aim of this critical narrative review is to assess the validity and clinical implications of episodic future thinking. A systematic review of episodic future thinking literature was conducted. PubMed and PsycInfo were searched through July 2015 for review and empirical articles with the following search terms: "episodic future thinking," "future mental simulation," "imagining the future," "imagining new experiences," "future mental time travel," "future autobiographical experience," and "prospection." The review discusses evidence that episodic future thinking is important for adaptive functioning, which has implications for neurological populations. To determine the validity of episodic future thinking, the construct is evaluated with respect to related constructs, such as imagination, episodic memory, autobiographical memory, prospective memory, narrative construction, and working memory. Although it has been minimally investigated, there is evidence of convergent and discriminant validity for episodic future thinking. Research has not addressed the incremental validity of episodic future thinking. Practical considerations of episodic future thinking tasks and related constructs in a clinical neuropsychological setting are considered. The utility of episodic future thinking is currently unknown due to the lack of research investigating the validity of episodic future thinking. Future work is discussed, which could determine whether episodic future thinking is an important missing piece in standard clinical neuropsychological assessment. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Educational Futures: Dominant and Contesting Visions

ERIC Educational Resources Information Center

Milojevic, Ivana

2011-01-01

This book provides an overview and analysis of current tensions, debates and key issues within OECD nations, particularly Australia, the USA, Canada and the UK, with regard to where education is and should be going. Using a broad historical analysis, it investigates ideas and visions about the future that are increasingly evoked to support…

Liberating the Oppressed: Research Knowledge Differentials and Ethical Investigation in Special Operations Forces Clinical Science.

PubMed

Kemplin, Kate Rocklein; Bowling, F Young

Special Operations Forces (SOF) medics do not have preparation in research knowledge that enables them to independently initiate or generate their own studies. Thus, medics rely on evidence generated by others, who are removed from medics' practice environment. Here, salient literature on research self-efficacy and the genesis of institutional review boards (IRBs) are reviewed and interpreted for contextual applications to medics' practice and initiation of studies. More publications delving into research methods are warranted to promote medics' participation and initiation of selfdirected scientific investigation, in collaboration with research scientists. 2017.

Astrium Preparation of Future Cryogenic Thrust Chamber Development

NASA Astrophysics Data System (ADS)

Nicolay, Rolf

2002-01-01

The scenarios for future cryogenic propulsion in Europe are mainly governed by cost issues on the one side and performance issues on the other. Certain relationships of the different issues exist to either the application for ELVs or RLVs respectively. Taking into account the limited budgets of the Europeans Agency Market, flexible development strategies are and have to be defined to fulfill both applications requirements. Investigations aiming at identifying the optimum development strategy serving both applications have been performed. Based on the experience of the different cryogenic thrust chamber developments already performed, Astrium worked out a flexible development strategy for future cryogenic thrust chambers in order to: This paper is going to report about this development strategy and the associated derived needs for technological investigations and development work.

Life Sciences Investigations for ESA's First Lunar Lander

NASA Astrophysics Data System (ADS)

Carpenter, J. D.; Angerer, O.; Durante, M.; Linnarson, D.; Pike, W. T.

2010-12-01

Preparing for future human exploration of the Moon and beyond is an interdisciplinary exercise, requiring new technologies and the pooling of knowledge and expertise from many scientific areas. The European Space Agency is working to develop a Lunar Lander, as a precursor to future human exploration activities. The mission will demonstrate new technologies and perform important preparatory investigations. In the biological sciences the two major areas requiring investigation in advance of human exploration are radiation and its effects on human physiology and the potential toxicity of lunar dust. This paper summarises the issues associated with these areas and the investigations planned for the Lunar Lander to address them.

Futures Conditional.

ERIC Educational Resources Information Center

Theobald, Robert

The readings presented here are designed to help the reader perceive the future more vividly. Part one of the book suggests the various ways in which the future can be seen; it includes science fiction and the views of various analysts as to what the future holds. Part two collects printed materials about the future from various sources, including…

Predicting future violence among individuals with psychopathy.

PubMed

Coid, Jeremy W; Ullrich, Simone; Kallis, Constantinos

2013-11-01

Structured risk assessment aims to help clinicians classify offenders according to likelihood of future violent and criminal behaviour. We investigated how confident clinicians can be using three commonly used instruments (HCR-20, VRAG, OGRS-II) in individuals with different diagnoses. Moderate to good predictive accuracy for future violence was achieved for released prisoners with no mental disorder, low to moderate for clinical syndromes and personality disorder, but accuracy was no better than chance for individuals with psychopathy. Comprehensive diagnostic assessment should precede an assessment of risk. Risk assessment instruments cannot be relied upon when managing public risk from individuals with psychopathy.

Investigating the Quality of Service of Current and Future Tactical Information Exchanges - Net Warrior

DTIC Science & Technology

2010-05-01

as Link-11, Link-16 and VMF. It also includes future systems such as Link-22 (using the typical HF & UHF frequency bands) and technologies that...triangulate and find the precise geolocation of the enemy target. If the target happens to relocate, TTNT is able to update the target with high accuracy...22 operates in either the HF or UHF frequency bands. In each of these frequency bands the system can operate on a single frequency or a pseudo-random

The Past, Present, and Future of Public Health Surveillance

PubMed Central

Choi, Bernard C. K.

2012-01-01

This paper provides a review of the past, present, and future of public health surveillance—the ongoing systematic collection, analysis, interpretation, and dissemination of health data for the planning, implementation, and evaluation of public health action. Public health surveillance dates back to the first recorded epidemic in 3180 B.C. in Egypt. Hippocrates (460 B.C.–370 B.C.) coined the terms endemic and epidemic, John Graunt (1620–1674) introduced systematic data analysis, Samuel Pepys (1633–1703) started epidemic field investigation, William Farr (1807–1883) founded the modern concept of surveillance, John Snow (1813–1858) linked data to intervention, and Alexander Langmuir (1910–1993) gave the first comprehensive definition of surveillance. Current theories, principles, and practice of public health surveillance are summarized. A number of surveillance dichotomies, such as epidemiologic surveillance versus public health surveillance, are described. Some future scenarios are presented, while current activities that can affect the future are summarized: exploring new frontiers; enhancing computer technology; improving epidemic investigations; improving data collection, analysis, dissemination, and use; building on lessons from the past; building capacity; enhancing global surveillance. It is concluded that learning from the past, reflecting on the present, and planning for the future can further enhance public health surveillance. PMID:24278752

Multifractal spectrum analysis of nonlinear dynamical mechanisms in China’s agricultural futures markets

NASA Astrophysics Data System (ADS)

Chen, Shu-Peng; He, Ling-Yun

2010-04-01

Based on Partition Function and Multifractal Spectrum Analysis, we investigated the nonlinear dynamical mechanisms in China’s agricultural futures markets, namely, Dalian Commodity Exchange (DCE for short) and Zhengzhou Commodity Exchange (ZCE for short), where nearly all agricultural futures contracts are traded in the two markets. Firstly, we found nontrivial multifractal spectra, which are the empirical evidence of the existence of multifractal features, in 4 representative futures markets in China, that is, Hard Winter wheat (HW for short) and Strong Gluten wheat (SG for short) futures markets from ZCE and Soy Meal (SM for short) futures and Soy Bean No.1 (SB for short) futures markets from DCE. Secondly, by shuffling the original time series, we destroyed the underlying nonlinear temporal correlation; thus, we identified that long-range correlation mechanism constitutes major contributions in the formation in the multifractals of the markets. Thirdly, by tracking the evolution of left- and right-half spectra, we found that there exist critical points, between which there are different behaviors, in the left-half spectra for large price fluctuations; but for the right-hand spectra for small price fluctuations, the width of those increases slowly as the delay t increases in the long run. Finally, the dynamics of large fluctuations is significantly different from that of the small ones, which implies that there exist different underlying mechanisms in the formation of multifractality in the markets. Our main contributions focus on that we not only provided empirical evidence of the existence of multifractal features in China agricultural commodity futures markets; but also we pioneered in investigating the sources of the multifractality in China’s agricultural futures markets in current literature; furthermore, we investigated the nonlinear dynamical mechanisms based on spectrum analysis, which offers us insights into the underlying dynamical mechanisms in

The Future Value of Interscholastic Participation: An Analysis of the Impact of Participation on Future Earnings and Educational Attainment

ERIC Educational Resources Information Center

Watson, William R.

2009-01-01

The purpose of this research was to investigate the future value of interscholastic participation in extracurricular activities on the individual student level. In this study, two relationships were examined: (a) the relationship between high school student participation and postsecondary educational attainment, and (b) the relationship between…

Hepatic pseudoaneurysm after traumatic liver injury; is CT follow-up warranted?

PubMed

Østerballe, Lene; Helgstrand, Frederik; Axelsen, Thomas; Hillingsø, Jens; Svendsen, Lars Bo

2014-01-01

Hepatic pseudoaneurysm (HPA) is a rare complication after liver trauma, yet it is potentially fatal, as it can lead to sudden severe haemorrhage. The risk of developing posttraumatic HPA is one of the arguments for performing follow-up CT of patients with liver injuries. The aim of this study was to investigate the occurrence of HPA post liver trauma. A retrospective study from 2000-2010 of conservatively treated patients with blunt liver trauma was performed to investigate the incidence and nature of HPA. After the initial CT scan patients were admitted to the department and if not clinically indicated prior a follow-up CT was performed on day 4-5. A total of 259 non-operatively managed patients with liver injury were reviewed. 188 had a follow-up CT or US and in 7 patients a HPA was diagnosed. All aneurysms were treated with angiographic embolization and there were no treatment failures. There was no correlation between the severity of the liver injury and development of HPA. 5 out of 7 patients were asymptomatic and would have been discharged without treatment if the protocol did not include a default follow-up CT. In conclusion, this study shows that HPA is not correlated to the severity of liver injury and it develops in 4% of patients after traumatic liver injury. In order to avoid potentially life-threatening haemorrhage from a post trauma hepatic pseudoaneurysm, it seems appropriate to do follow-up CT as part of the conservative management of blunt and penetrating liver injuries.

PD-1/PD-L1 inhibitors in multiple myeloma: The present and the future

PubMed Central

Jelinek, T.; Hajek, R.

2016-01-01

ABSTRACT The introduction of PD-1/PD-L1 pathway inhibitors has marked a significant milestone in the treatment of various types of solid tumors. The current situation in multiple myeloma (MM) is rather unclear, as distinct research groups have reported discordant results. This discrepancy dominantly concerns the expression of PD-1/PD-L1 molecules as well as the identification of the responsible immune effector cell population. The results of monotherapy with PD-1/PD-L1 inhibitors have been unsatisfactory in MM, suggesting that a combination approach is needed. The most logical partners are immunomodulatory agents as they possess many synergistic effects. We are also proposing other rational and promising combinations (e.g., daratumumab, ibrutinib, anti-CD137) that warrant further investigation. PMID:28123899

Indigenous Secondary Education in the Northern Territory: Building for the Future

ERIC Educational Resources Information Center

Herbert, Jeannie; McInerney, Dennis M.; Fasoli, Lyn; Stephenson, Peter; Ford, Lysbeth

2014-01-01

This article reports on the findings of an Australian Research Council (ARC) funded research project, "Building the future for Indigenous students", an investigation of the hopes and dreams for the future of over 1,000 secondary students, 733 of whom were Indigenous, living in very remote, remote, and urban locations in the Northern…

Introduction of the Space Shuttle Columbia Accident, Investigation Details, Findings and Crew Survival Investigation Report

NASA Technical Reports Server (NTRS)

Chandler, Michael

2010-01-01

As the Space Shuttle Program comes to an end, it is important that the lessons learned from the Columbia accident be captured and understood by those who will be developing future aerospace programs and supporting current programs. Aeromedical lessons learned from the Accident were presented at AsMA in 2005. This Panel will update that information, closeout the lessons learned, provide additional information on the accident and provide suggestions for the future. To set the stage, an overview of the accident is required. The Space Shuttle Columbia was returning to Earth with a crew of seven astronauts on 1Feb, 2003. It disintegrated along a track extending from California to Louisiana and observers along part of the track filmed the breakup of Columbia. Debris was recovered from Littlefield, Texas to Fort Polk, Louisiana, along a 567 statute mile track; the largest ever recorded debris field. The Columbia Accident Investigation Board (CAIB) concluded its investigation in August 2003, and released their findings in a report published in February 2004. NASA recognized the importance of capturing the lessons learned from the loss of Columbia and her crew and the Space Shuttle Program managers commissioned the Spacecraft Crew Survival Integrated Investigation Team (SCSIIT) to accomplish this. Their task was to perform a comprehensive analysis of the accident, focusing on factors and events affecting crew survival, and to develop recommendations for improving crew survival, including the design features, equipment, training and procedures intended to protect the crew. NASA released the Columbia Crew Survival Investigation Report in December 2008. Key personnel have been assembled to give you an overview of the Space Shuttle Columbia accident, the medical response, the medico-legal issues, the SCSIIT findings and recommendations and future NASA flight surgeon spacecraft accident response training. Educational Objectives: Set the stage for the Panel to address the

Investigating head and trunk rotation in sitting: a pilot study comparing people after stroke and healthy controls.

PubMed

Verheyden, Geert; Ashburn, Ann; Burnett, Malcolm; Littlewood, Janet; Kunkel, Dorit

2012-06-01

Healthy individuals have a top-down coordination pattern when turning while walking; they first rotate the head, then the shoulders, the pelvis and, finally, the feet. The aim of this study was to compare spatial and temporal characteristics of head and trunk rotation in sitting between people early after stroke and healthy participants, and investigate change over time. This was a pilot, quantitative, longitudinal study. We recruited participants from stroke wards and local groups. People with stroke were assessed at 3, 6 and 12 weeks after stroke. Healthy participants were examined with the same weekly intervals. Participants were in a seated position and were asked verbally to rotate their head and look at a visual signal placed at 90° to the left and to the right of the subject. CODAmotion (Charnwood Dynamics Ltd, Rothley, UK) was used for 3-D motion recording and analysis. Healthy participants (two women and four men; mean age 66 years) showed significant rotation of the head before rotation of the shoulders at all three time points; people with stroke (one woman and five men; mean age 71 years) did not show this top-down pattern of movement. There was no significant difference between start times of head and shoulder rotation at 3 (p = 0.167), 6 (p = 0.084) and 12 weeks after stroke (p = 0.062). Conclusions. The results of our pilot study warrant further investigation into the recovery and pattern of axial coordination after stroke. Future studies could provide insight into the mechanisms behind impaired postural control in people after stroke. Copyright © 2011 John Wiley & Sons, Ltd.

Investigating the Aftermath of Terror: Fundamental Outcomes, Methodological Choices, and Future Directions.

PubMed

Gradus, Jaimie L; Marx, Brian P; Sloan, Denise M

2016-06-01

Acts of terrorism are becoming increasingly common throughout the world. These events represent a significant public health concern given the associated health consequences. Although it is clear that terrorist attacks have mental and physical health sequelae, the exact nature and prevalence of these consequences are unclear. Epidemiological research can play an important role in better understanding the mental and physical impact of terrorist attacks. In this editorial, we highlight recent epidemiological research on these terrorism-related health outcomes. We also provide suggestions for how future studies can build on the existing literature and describe ways in which epidemiological methods can be harnessed to extend the current literature. Lastly, we offer recommendations on how to best prepare communities for the aftermath of terrorist attacks, highlighting secondary intervention and prevention strategies. Overall, multilevel strategies are needed to adequately cope with the growing rise of terrorist acts, and these strategies will have to be reassessed as the nature of terrorist attacks changes.

Investigating Differences between Modeled Historical and Station Calculated Drought

EPA Science Inventory

With growing concern over increased frequency and intensity of extreme climate events, there is an imperative need to investigate drought under different future scenarios for the contiguous U.S. To assess future drought relative to a historical baseline, drought occurrence (numbe...

On the Predictability of Future Impact in Science

PubMed Central

Penner, Orion; Pan, Raj K.; Petersen, Alexander M.; Kaski, Kimmo; Fortunato, Santo

2013-01-01

Correctly assessing a scientist's past research impact and potential for future impact is key in recruitment decisions and other evaluation processes. While a candidate's future impact is the main concern for these decisions, most measures only quantify the impact of previous work. Recently, it has been argued that linear regression models are capable of predicting a scientist's future impact. By applying that future impact model to 762 careers drawn from three disciplines: physics, biology, and mathematics, we identify a number of subtle, but critical, flaws in current models. Specifically, cumulative non-decreasing measures like the h-index contain intrinsic autocorrelation, resulting in significant overestimation of their “predictive power”. Moreover, the predictive power of these models depend heavily upon scientists' career age, producing least accurate estimates for young researchers. Our results place in doubt the suitability of such models, and indicate further investigation is required before they can be used in recruiting decisions. PMID:24165898

Procrastination, consideration of future consequences, and episodic future thinking.

PubMed

Rebetez, Marie My Lien; Barsics, Catherine; Rochat, Lucien; D'Argembeau, Arnaud; Van der Linden, Martial

2016-05-01

Despite the intrinsic temporal nature of procrastination, little research has examined the link between this form of self-regulatory failure and the consideration of future consequences, and no study has addressed the link between procrastination and episodic future thinking. The aim of the present study was to explore these relationships. Participants were asked to project themselves into possible future events and to rate the amount of sensory-perceptual details and autonoetic consciousness associated with their representations. They were also asked to complete questionnaires that assessed procrastination, the consideration of future consequences, and negative affect. Results showed that both the consideration of future consequences and episodic future thinking were associated with procrastination, and in particular with procrastination-related decision making abilities and procrastination-related motivational dispositions, respectively. Copyright © 2016 Elsevier Inc. All rights reserved.

Parental Warmth and Risks of Substance Use in Children with Attention-Deficit/Hyperactivity Disorder: Findings from a 10–12 Year Longitudinal Investigation

PubMed Central

Tandon, Mini; Tillman, Rebecca; Spitznagel, Edward; Luby, Joan

2013-01-01

Objective The study examined factors in the risk trajectory for Substance Use Disorder (SUD) over a 10–12 year period in children with ADHD. Method N=145 children between the ages of 7 and 16 with ADHD and healthy controls were assessed every 2 years for 10–12 years as part of a larger, longitudinal investigation. Onset of substance use disorder was examined using Cox proportional hazards modeling, and included child and parent psychopathology, and parental warmth as well as other key factors. Results Low paternal warmth and maternal SUD were predictors of SUD in n=59 ADHD participants after adjusting for gender, child ODD, paternal SUD, maternal/paternal ADHD, maternal/paternal major depressive disorder (MDD), maternal/paternal anxiety, and low maternal warmth in the Cox model. Conclusions Longitudinal study findings suggest that in addition to the established risk of ADHD and maternal SUD in development of child SUD, low paternal warmth is also associated with onset of SUD. This was evident after controlling for pertinent parent and child psychopathology. These findings suggest that paternal warmth warrants further investigation as a key target for novel interventions to prevent SUD in children with ADHD. More focused investigations examining paternal parenting factors in addition to parent and child psychopathology in the risk trajectory from ADHD to SUD are now warranted. PMID:24955084

Episodic future thinking reduces delay discounting and cigarette demand: an investigation of the good-subject effect.

PubMed

Stein, Jeffrey S; Tegge, Allison N; Turner, Jamie K; Bickel, Warren K

2018-04-01

Episodic future thinking (EFT), an intervention involving mental simulation of future events, has been shown to reduce both delay discounting and cigarette self-administration. In the present study, we extended these findings by showing that EFT in a web-based sample of smokers reduces delay discounting and intensity of demand for cigarettes (ad libitum consumption) in a hypothetical purchase task. No effect was observed on elasticity of demand (sensitivity to price) or cigarette craving. We also explored whether demand characteristics (specifically, the "good-subject" effect) might be responsible for observed effects. EFT participants were significantly better able than control participants to discern the experimental hypothesis. However, EFT participants were not better than controls at identifying whether they had been assigned to the experimental group and, likewise, showed no differences in attitudes about the experiment and experimenter. Importantly, effects of EFT on delay discounting and demand remained significant even when controlling for measures of demand characteristics, indicating that EFT's effects are independent of participants' perceptions about the experiment.

Establishment of sustainable health science for future generations: from a hundred years ago to a hundred years in the future.

PubMed

Mori, Chisato; Todaka, Emiko

2009-01-01

Recently, we have investigated the relationship between environment and health from a scientific perspective and developed a new academic field, "Sustainable Health Science" that will contribute to creating a healthy environment for future generations. There are three key points in Sustainable Heath Science. The first key point is "focusing on future generations"-society should improve the environment and prevent possible adverse health effects on future generations (Environmental Preventive Medicine). The second key point is the "precautious principle". The third key point is "transdisciplinary science", which means that not only medical science but also other scientific fields, such as architectural and engineering science, should be involved. Here, we introduce our recent challenging project "Chemiless Town Project", in which a model town is under construction with fewer chemicals. In the project, a trial of an education program and a health-examination system of chemical exposure is going to be conducted. In the future, we are aiming to establish health examination of exposure to chemicals of women of reproductive age so that the risk of adverse health effects to future generations will decrease and they can enjoy a better quality of life. We hope that society will accept the importance of forming a sustainable society for future generations not only with regard to chemicals but also to the whole surrounding environment. As the proverb of American native people tells us, we should live considering the effects on seven generations in the future.

17 CFR 8.06 - Investigations.

Code of Federal Regulations, 2010 CFR

2010-04-01

....06 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXCHANGE PROCEDURES FOR DISCIPLINARY, SUMMARY, AND MEMBERSHIP DENIAL ACTIONS Disciplinary Procedure § 8.06 Investigations. (a) Each exchange shall establish and maintain a disciplinary procedure which requires the enforcement staff of the...

Titan's Atmosphere and Surface Explored by Future in Situ Balloon Investigations

NASA Astrophysics Data System (ADS)

Coustenis, Athena; OPAG Titan Working Group

2009-09-01

A wide range of high priority scientific questions for Titan remain to be addressed after Cassini-Huygens, some of which cannot be comprehensively addressed by any envisioned extension of Cassini flybys due to its inherent limitations and require both remote and in situ investigation. Whereas a spacecraft in orbit around Titan could allow for a thorough investigation of Titan's upper atmosphere, there are questions that can only be answered by extending the measurements into Titan's lower atmosphere and down to the surface. Key steps toward the synthesis of prebiotic molecules that may have been present on the early Earth as precursors to life might be occurring high in the atmosphere, the products then descending towards the surface where they might replicate. In situ chemical analysis of gases, liquids and solids, both in the atmosphere and on the surface, would enable the identification of chemical species that are present and how far such putative reactions have advanced. The rich inventory of complex organic molecules that are known or suspected to be present in the lower atmosphere and at the surface gives Titan a strong astrobiological potential. Our understanding of the forces that shape Titan's diverse landscape and interior will benefit greatly from detailed investigations at a variety of locations, a demanding requirement anywhere else, but one that is uniquely possible at Titan using a hot-air balloon (montgolfière). Indeed, Titan's thick cold atmosphere and low gravity make the deployment of in situ elements using parachutes (as demonstrated by the Cassini-Huygens probe) and balloons vastly easier than for any other solar system body. A balloon floating across the Titan landscape for long periods of time, with an adapted payload, would offer the mobility required to explore the diversity of Titan in a way that cannot be achieved with any other platform.

Future orientation, impulsivity, and problem behaviors: a longitudinal moderation model.

PubMed

Chen, Pan; Vazsonyi, Alexander T

2011-11-01

In the current study, based on a sample of 1,873 adolescents between 11.4 and 20.9 years of age from the first 3 waves of the National Longitudinal Study of Adolescent Health, we investigated the longitudinal effects of future orientation on levels of and developmental changes in problem behaviors, while controlling for the effects by impulsivity; we also tested the moderating effects by future orientation on the impulsivity-problem behaviors link over time. Additionally, we examined future orientation operationalized by items measuring education, marriage, and life domains. Findings based on growth curve analyses provided evidence of longitudinal effects by education and life future orientation on both levels of and developmental changes in problem behaviors; the effect of marriage future orientation was not significant for either test. In addition, only life future orientation moderated the effect by impulsivity on levels of problem behaviors over time. More specifically, impulsivity had a weaker effect on levels of problem behaviors over time for adolescents who reported higher levels of life future orientation.

Formation of the Professional and Didactic Culture of the Future Teacher

ERIC Educational Resources Information Center

Mirzagitova, Alsu L.; Akhmetov, Linar G.

2016-01-01

Relevance: The relevance of the problem under investigation is caused by the fact that the problem of the formation of the professional and didactic culture of future teachers has not been sufficiently elaborated. The purpose of the article: The article aims to the solution of the problem of improving the content of future teachers' training with…

Multivariate pattern recognition for diagnosis and prognosis in clinical neuroimaging: state of the art, current challenges and future trends.

PubMed

Haller, Sven; Lovblad, Karl-Olof; Giannakopoulos, Panteleimon; Van De Ville, Dimitri

2014-05-01

Many diseases are associated with systematic modifications in brain morphometry and function. These alterations may be subtle, in particular at early stages of the disease progress, and thus not evident by visual inspection alone. Group-level statistical comparisons have dominated neuroimaging studies for many years, proving fascinating insight into brain regions involved in various diseases. However, such group-level results do not warrant diagnostic value for individual patients. Recently, pattern recognition approaches have led to a fundamental shift in paradigm, bringing multivariate analysis and predictive results, notably for the early diagnosis of individual patients. We review the state-of-the-art fundamentals of pattern recognition including feature selection, cross-validation and classification techniques, as well as limitations including inter-individual variation in normal brain anatomy and neurocognitive reserve. We conclude with the discussion of future trends including multi-modal pattern recognition, multi-center approaches with data-sharing and cloud-computing.

Time perspective and volunteerism: The importance of focusing on the future.

PubMed

Maki, Alexander; Dwyer, Patrick C; Snyder, Mark

2016-01-01

Because volunteerism is a planned activity that unfolds over time, people who more frequently focus on the future might also be more likely to initiate volunteerism and sustain it over time. Using longitudinal (Study 1) and experimental (Study 2) paradigms, we investigated whether time perspective, and in particular a person's orientation toward the future, is related to volunteers' beliefs and behavior. In Study 1, a person's dispositional level of future time perspective was closely linked to volunteer beliefs and behavior. In Study 2, people who wrote about the future reported higher intentions to volunteer, and this was particularly true for infrequent volunteers and those with lower levels of dispositional future time perspective. Across two studies, we found evidence that future time perspective, whether a chronic disposition or a pattern of thought elicited by someone else, is linked to volunteer beliefs and behavior.

Plume induced environments on future lunar mission vehicles

NASA Technical Reports Server (NTRS)

Rochelle, Bill; Hughes, Ruston; Fitzgerald, Steve

1992-01-01

The objective of this presentation is to identify potential plume heating/impingement problem areas on vehicles used for future lunar missions. This is accomplished by comparison with lunar module plume investigations performed during 1968-1971. All material is presented in viewgraph format.

Columbia Crew Survival Investigation Report

NASA Technical Reports Server (NTRS)

2009-01-01

NASA commissioned the Columbia Accident Investigation Board (CAIB) to conduct a thorough review of both the technical and the organizational causes of the loss of the Space Shuttle Columbia and her crew on February 1, 2003. The accident investigation that followed determined that a large piece of insulating foam from Columbia s external tank (ET) had come off during ascent and struck the leading edge of the left wing, causing critical damage. The damage was undetected during the mission. The CAIB's findings and recommendations were published in 2003 and are available on the web at http://caib.nasa.gov/. NASA responded to the CAIB findings and recommendations with the Space Shuttle Return to Flight Implementation Plan. Significant enhancements were made to NASA's organizational structure, technical rigor, and understanding of the flight environment. The ET was redesigned to reduce foam shedding and eliminate critical debris. In 2005, NASA succeeded in returning the space shuttle to flight. In 2010, the space shuttle will complete its mission of assembling the International Space Station and will be retired to make way for the next generation of human space flight vehicles: the Constellation Program. The Space Shuttle Program recognized the importance of capturing the lessons learned from the loss of Columbia and her crew to benefit future human exploration, particularly future vehicle design. The program commissioned the Spacecraft Crew Survival Integrated Investigation Team (SCSIIT). The SCSIIT was asked to perform a comprehensive analysis of the accident, focusing on factors and events affecting crew survival, and to develop recommendations for improving crew survival for all future human space flight vehicles. To do this, the SCSIIT investigated all elements of crew survival, including the design features, equipment, training, and procedures intended to protect the crew. This report documents the SCSIIT findings, conclusions, and recommendations.

Melanoma Vaccines: Mixed Past, Promising Future

PubMed Central

Ozao-Choy, Junko; Lee, Delphine J.; Faries, Mark B.

2014-01-01

Synopsis Cancer vaccines were one of the earliest forms of immunotherapy to be investigated. Past attempts to vaccinate against cancer, including melanoma, have mixed results, revealing the complexity of what was thought to be a simple concept. However, several recent successes and the combination of improved knowledge of tumor immunology and the advent of new immunomodulators make vaccination a promising strategy for the future. PMID:25245965

Identifying Martian Hydrothermal Sites: Geological Investigation Utilizing Multiple Datasets

NASA Technical Reports Server (NTRS)

Dohm, J. M.; Baker, V. R.; Anderson, R. C.; Scott, D. H.; Rice, J. W., Jr.; Hare, T. M.

2000-01-01

Comprehensive geological investigations of martian landscapes that may have been modified by magmatic-driven hydrothermal activity, utilizing multiple datasets, will yield prime target sites for future hydrological, mineralogical, and biological investigations.

Investigating the feasibility and acceptability of health psychology-informed obesity training for medical students.

PubMed

Chisholm, Anna; Hart, Jo; Mann, Karen; Perry, Mark; Duthie, Harriet; Rezvani, Leila; Peters, Sarah

2016-01-01

Health psychologists have succeeded in identifying theory-congruent behaviour change techniques (BCTs) to prevent and reduce lifestyle-related illnesses, such as cardiovascular disease, cancers and diabetes. Obesity management discussions between doctors and patients can be challenging and are often avoided. Despite a clear training need, it is unknown how best to tailor BCT research findings to inform obesity-management training for future healthcare professionals. The primary objective of this descriptive study was to gather information on the feasibility and acceptability of delivering and evaluating health psychology-informed obesity training to UK medical students. Medical students (n = 41) attended an obesity management session delivered by GP tutors. Sessions were audio-recorded to enable fidelity checks. Acceptability of training was explored qualitatively. Tutors consistently delivered training according to the intervention protocol; and students and tutors found the training highly acceptable. This psychology-informed training can be delivered successfully by GP tutors and further research is warranted to explore its efficacy.

Eagle-eyed visual acuity: an experimental investigation of enhanced perception in autism.

PubMed

Ashwin, Emma; Ashwin, Chris; Rhydderch, Danielle; Howells, Jessica; Baron-Cohen, Simon

2009-01-01

Anecdotal accounts of sensory hypersensitivity in individuals with autism spectrum conditions (ASC) have been noted since the first reports of the condition. Over time, empirical evidence has supported the notion that those with ASC have superior visual abilities compared with control subjects. However, it remains unclear whether these abilities are specifically the result of differences in sensory thresholds (low-level processing), rather than higher-level cognitive processes. This study investigates visual threshold in n = 15 individuals with ASC and n = 15 individuals without ASC, using a standardized optometric test, the Freiburg Visual Acuity and Contrast Test, to investigate basic low-level visual acuity. Individuals with ASC have significantly better visual acuity (20:7) compared with control subjects (20:13)-acuity so superior that it lies in the region reported for birds of prey. The results of this study suggest that inclusion of sensory hypersensitivity in the diagnostic criteria for ASC may be warranted and that basic standardized tests of sensory thresholds may inform causal theories of ASC.

Predictors of Future Performance in Architectural Design Education

ERIC Educational Resources Information Center

Roberts, A. S.

2007-01-01

The link between academic performance in secondary education and the subsequent performance of students studying architecture at university level is commonly questioned by educators and admissions tutors. This paper investigates the potential for using measures of cognitive style and spatial ability as predictors of future potential in…

Future Direction of USDA Forest Service Research

Treesearch

A. Dan Wilson

1995-01-01

The USDA Forest Service has been involved in Texas oak wilt research since 1976. Despite research successes, there are still many important research areas that have not been addressed or sufficiently investigated to answer the key questions required for making sound disease management decisions. Some of the priority areas planned for future research by the Southern...

Middle School Girls' Envisioned Future in Computing

ERIC Educational Resources Information Center

Friend, Michelle

2015-01-01

Experience is necessary but not sufficient to cause girls to envision a future career in computing. This study investigated the experiences and attitudes of girls who had taken three years of mandatory computer science classes in an all-girls setting in middle school, measured at the end of eighth grade. The one third of participants who were open…

Biopesticides: state of the art and future opportunities.

PubMed

Seiber, James N; Coats, Joel; Duke, Stephen O; Gross, Aaron D

2014-12-03

The use of biopesticides and related alternative management products is increasing. New tools, including semiochemicals and plant-incorporated protectants (PIPs), as well as botanical and microbially derived chemicals, are playing an increasing role in pest management, along with plant and animal genetics, biological control, cultural methods, and newer synthetics. The goal of this Perspective is to highlight promising new biopesticide research and development (R&D), based upon recently published work and that presented in the American Chemical Society (ACS) symposium "Biopesticides: State of the Art and Future Opportunities," as well as the authors' own perspectives. Although the focus is on biopesticides, included in this Perspective is progress with products exhibiting similar characteristics, namely those naturally occurring or derived from natural products. These are target specific, of low toxicity to nontarget organisms, reduced in persistence in the environment, and potentially usable in organic agriculture. Progress is being made, illustrated by the number of biopesticides and related products in the registration pipeline, yet major commercial opportunities exist for new bioherbicides and bionematicides, in part occasioned by the emergence of weeds resistant to glyphosate and the phase-out of methyl bromide. The emergence of entrepreneurial start-up companies, the U.S. Environmental Protection Agency (EPA) fast track for biopesticides, and the availability of funding for registration-related R&D for biorational pesticides through the U.S. IR-4 program provide incentives for biopesticide development, but an expanded effort is warranted both in the United States and worldwide to support this relatively nascent industry.

Exposing the dark sector with future Z factories

NASA Astrophysics Data System (ADS)

Liu, Jia; Wang, Lian-Tao; Wang, Xiao-Ping; Xue, Wei

2018-05-01

We investigate the prospects of searching dark sector models via exotic Z -boson decay at future e+e- colliders with Giga Z and Tera Z options. Four general categories of dark sector models, Higgs portal dark matter, vector-portal dark matter, inelastic dark matter, and axionlike particles, are considered. Focusing on channels motivated by the dark sector models, we carry out a model-independent study of the sensitivities of Z factories in probing exotic decays. The limits on branching ratios of the exotic Z decay are typically O (10-6- 10-8.5) for the Giga Z and O (10-7.5- 10-11) for the Tera Z , and they are compared with the projection for the high luminosity LHC. We demonstrate that future Z factories can provide its unique and leading sensitivity and highlight the complementarity with other experiments, including the indirect and direct dark matter search limits and the existing collider limits. Future Z factories will play a leading role in uncovering the hidden sector of the Universe in the future.

Future DUNE constraints on EFT

NASA Astrophysics Data System (ADS)

Falkowski, Adam; Grilli di Cortona, Giovanni; Tabrizi, Zahra

2018-04-01

In the near future, fundamental interactions at high-energy scales may be most efficiently studied via precision measurements at low energies. A universal language to assemble and interpret precision measurements is the so-called SMEFT, which is an effective field theory (EFT) where the Standard Model (SM) Lagrangian is extended by higher-dimensional operators. In this paper we investigate the possible impact of the DUNE neutrino experiment on constraining the SMEFT. The unprecedented neutrino flux offers an opportunity to greatly improve the current limits via precision measurements of the trident production and neutrino scattering off electrons and nuclei in the DUNE near detector. We quantify the DUNE sensitivity to dimension-6 operators in the SMEFT Lagrangian, and find that in some cases operators suppressed by an O(30) TeV scale can be probed. We also compare the DUNE reach to that of future experiments involving atomic parity violation and polarization asymmetry in electron scattering, which are sensitive to an overlapping set of SMEFT parameters.

San Mateo Creek Basin Phase I Site Investigation

EPA Pesticide Factsheets

The objective of the SI is to evaluate the Site using the Hazard Ranking System and the Superfund Chemical Data Matrix to determine if a threat to human health and the environment exists such that further action is warranted.

Future Scenarios as a Research Tool: Investigating Climate Change Impacts, Adaptation Options and Outcomes for the Great Barrier Reef, Australia.

PubMed

Evans, Louisa S; Hicks, Christina C; Fidelman, Pedro; Tobin, Renae C; Perry, Allison L

2013-01-01

Climate change is a significant future driver of change in coastal social-ecological systems. Our knowledge of impacts, adaptation options, and possible outcomes for marine environments and coastal industries is expanding, but remains limited and uncertain. Alternative scenarios are a way to explore potential futures under a range of conditions. We developed four alternative future scenarios for the Great Barrier Reef and its fishing and tourism industries positing moderate and more extreme (2-3 °C above pre-industrial temperatures) warming for 2050 and contrasting 'limited' and 'ideal' ecological and social adaptation. We presented these scenarios to representatives of key stakeholder groups to assess the perceived viability of different social adaptation options to deliver desirable outcomes under varied contexts.

Habits of cell phone usage and sperm quality - does it warrant attention?

PubMed

Zilberlicht, Ariel; Wiener-Megnazi, Zofnat; Sheinfeld, Yulia; Grach, Bronislava; Lahav-Baratz, Shirly; Dirnfeld, Martha

2015-09-01

Male infertility constitutes 30-40% of all infertility cases. Some studies have shown a continuous decline in semen quality since the beginning of the 20th century. One postulated contributing factor is radio frequency electromagnetic radiation emitted from cell phones. This study investigates an association between characteristics of cell phone usage and semen quality. Questionnaires accessing demographic data and characteristics of cell phone usage were completed by 106 men referred for semen analysis. Results were analysed according to WHO 2010 criteria. Talking for ≥1 h/day and during device charging were associated with higher rates of abnormal semen concentration (60.9% versus 35.7%, P < 0.04 and 66.7% versus 35.6%, P < 0.02, respectively). Among men who reported holding their phones ≤50 cm from the groin, a non-significantly higher rate of abnormal sperm concentration was found (47.1% versus 11.1%). Multivariate analysis revealed that talking while charging the device and smoking were risk factors for abnormal sperm concentration (OR = 4.13 [95% CI 1.28-13.3], P < 0.018 and OR = 3.04 [95% CI 1.14-8.13], P < 0.027, respectively). Our findings suggest that certain aspects of cell phone usage may bear adverse effects on sperm concentration. Investigation using large-scale studies is thus needed. Copyright © 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

The German joint research project "concepts for future gravity satellite missions"

NASA Astrophysics Data System (ADS)

Reubelt, Tilo; Sneeuw, Nico; Fichter, Walter; Müller, Jürgen

2010-05-01

Within the German joint research project "concepts for future gravity satellite missions", funded by the Geotechnologies programme of the German Federal Ministry of Education and Research, options and concepts for future satellite missions for precise (time-variable) gravity field recovery are investigated. The project team is composed of members from science and industry, bringing together experts in geodesy, satellite systems, metrology, sensor technology and control systems. The majority of team members already contributed to former gravity missions. The composition of the team guarantees that not only geodetic aspects and objectives are investigated, but also technological and financial constraints are considered. Conversely, satellite, sensor and system concepts are developed and improved in a direct exchange with geodetic and scientific claims. The project aims to develop concepts for both near and mid-term future satellite missions, taking into account e.g. advanced satellite formations and constellations, improved orbit design, innovative metrology and sensor systems and advances in satellite systems.

User Perspectives of the Future of the Internet.

ERIC Educational Resources Information Center

Barr, Trevor

This paper presents user perspectives on the future of the Internet. The first section discusses understanding users, including the difference between technology service offerings and potential uses, the need for investigation into the relationship between new communications technology and social behavior, and the shift from supply-led development…

Mental Contrasting of a Negative Future with a Positive Reality Regulates State Anxiety

PubMed Central

Brodersen, Gunnar; Oettingen, Gabriele

2017-01-01

Mental contrasting of a desired future with impeding reality is a self-regulatory strategy fostering goal pursuit. However, there is little research on mental contrasting of a negative future with a positive reality. We conducted two experiments, each with four experimental conditions, investigating the effects of mental contrasting a negative future with a positive reality on state anxiety: participants who mentally contrasted a negative future regarding a bacterial epidemic (Study 1, N = 199) or an idiosyncratic negative event (Study 2, N = 206) showed less state anxiety than participants who imagined the negative future only or who reverse contrasted; participants who mentally elaborated on the positive reality also showed less state anxiety. Our findings suggest that mental contrasting of a negative future helps people reduce disproportional anxiety regarding a negative future. PMID:28979223

Robotic Anterior and Midline Skull Base Surgery: Preclinical Investigations

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Malley, Bert W.; Weinstein, Gregory S.

Purpose: To develop a minimally invasive surgical technique to access the midline and anterior skull base using the optical and technical advantages of robotic surgical instrumentation. Methods and Materials: Ten experimental procedures focusing on approaches to the nasopharynx, clivus, sphenoid, pituitary sella, and suprasellar regions were performed on one cadaver and one live mongrel dog. Both the cadaver and canine procedures were performed in an approved training facility using the da Vinci Surgical Robot. For the canine experiments, a transoral robotic surgery (TORS) approach was used, and for the cadaver a newly developed combined cervical-transoral robotic surgery (C-TORS) approach wasmore » investigated and compared with standard TORS. The ability to access and dissect tissues within the various areas of the midline and anterior skull base were evaluated, and techniques to enhance visualization and instrumentation were developed. Results: Standard TORS approaches did not provide adequate access to the midline and anterior skull base; however, the newly developed C-TORS approach was successful in providing the surgical access to these regions of the skull base. Conclusion: Robotic surgery is an exciting minimally invasive approach to the skull base that warrants continued preclinical investigation and development.« less

The future of dream science.

PubMed

Bulkeley, Kelly

2017-10-01

This article describes the future prospects of scientific dream research. Three frontiers of investigation hold special promise: neuroscientific studies of the brain-mind system's activities during sleep (such as during lucid dreaming); systematic analyses of large collections of dream reports from diverse populations of people; and psychotherapeutic explorations of the multiple dimensions of personal and collective meaning woven into the dream experiences of each individual. Several helpful books on the science of sleep and dreaming are mentioned for further study. © 2017 New York Academy of Sciences.

Automatic Optimism: The Affective Basis of Judgments about the Likelihood of Future Events

ERIC Educational Resources Information Center

Lench, Heather C.

2009-01-01

People generally judge that the future will be consistent with their desires, but the reason for this desirability bias is unclear. This investigation examined whether affective reactions associated with future events are the mechanism through which desires influence likelihood judgments. In 4 studies, affective reactions were manipulated for…

Atomic-scale investigations of current and future devices: from nitride-based transistors to quantum computing

NASA Astrophysics Data System (ADS)

Gordon, Luke

Our era is defined by its technology, and our future is dependent on its continued evolution. Over the past few decades, we have witnessed the expansion of advanced technology into all walks of life and all industries, driven by the exponential increase in the speed and power of semiconductor-based devices. However, as the length scale of devices reaches the atomic scale, a deep understanding of atomistic theory and its application is increasingly crucial. In order to illustrate the power of an atomistic approach to understanding devices, we will present results and conclusions from three interlinked projects: n-type doping of III-nitride semiconductors, defects for quantum computing, and macroscopic simulations of devices. First, we will study effective n-type doping of III-nitride semiconductors and their alloys, and analyze the barriers to effective n-type doping of III-nitrides and their alloys. In particular, we will study the formation of DX centers, and predict alloy composition onsets for various III-nitride alloys. In addition, we will perform a comprehensive study of alternative dopants, and provide potential alternative dopants to improve n-type conductivity in AlN and wide-band-gap nitride alloys. Next, we will discuss how atomic-scale defects can act as a curse for the development of quantum computers by contributing to decoherence at an atomic scale, specifically investigating the effect of two-level state defects (TLS) systems in alumina as a source of decoherence in superconducting qubits based on Josephson junctions; and also as a blessing, by allowing the identification of wholly new qubits in different materials, specifically showing calculations on defects in SiC for quantum computing applications. Finally, we will provide examples of recent calculations we have performed for devices using macrosopic device simulations, largely in conjunction with first-principles calculations. Specifically, we will discuss the power of using a multi

Predictors of future anabolic androgenic steroid use.

PubMed

Wichstrøm, Lars

2006-09-01

To prospectively study the stability of anabolic androgenic steroid (AAS) use and predictors of AAS use, and to investigate whether AAS use alters the risk of later emotional and behavioral problems. Survey of a national sample of Norwegian high school students (age 15-19) in 1994 followed up in 1999 (N = 2924). Measures of frequent alcohol intoxication (50+ times per 12 months), cannabis use (12 months), hard drug use (12 months), being offered cannabis, eating problems, conduct problems, sexual debut before age 15, BMI, involvement in power sports, perceived physical appearance, and satisfaction with body parts were obtained. Life-time prevalence of AAS use were 1.9 and 0.8% in the follow-up period. Multivariate logistic regression revealed that future AAS use was predicted by young age, male gender, previous AAS use, involvement in power sports, and frequent alcohol intoxication. AAS use did not predict future emotional or behavioral problems other than reducing the risk of future frequent alcohol intoxication. Frequent alcohol intoxication and involvement in power sports appear to predict future AAS use. At the population level there was little stability in individual AAS use from adolescence to early adulthood. No detrimental effects of AAS use could be detected in this study, but low statistical power limits this conclusion.

SO-QT: Collaborative Tool to Project the Future Space Object Population

NASA Technical Reports Server (NTRS)

Stupl, Jan

2017-01-01

Earth orbit gets increasingly congested, a challenge to space operators, both in governments and industry. We present a web tool that provides: 1) data on todays and the historic space object environments, by aggregating object-specific tracking data; and 2) future trends through a collaboration platform to collect information on planed launches. The collaborative platform enables experts to pool and compare their data in order to generate future launch scenarios. The tool is intended to support decision makers and mission designers while they investigate future missions and scholars as they develop strategies for space traffic management.

Positron Computed Tomography: Current State, Clinical Results and Future Trends

DOE R&D Accomplishments Database

Schelbert, H. R.; Phelps, M. E.; Kuhl, D. E.

1980-09-01

An overview is presented of positron computed tomography: its advantages over single photon emission tomography, its use in metabolic studies of the heart and chemical investigation of the brain, and future trends. (ACR)

Future HIV Mentoring Programs to Enhance Diversity.

PubMed

Stoff, David M; Cargill, Victoria A

2016-09-01

This paper proposes a general template to guide future mentoring program development addressing: (i) considerations to ensure an adequate research workforce; (ii) key guidelines and principles of mentoring; and (iii) use of a logic model to develop program milestones, outcomes and evaluation. We focus on these areas to guide and inform the most effective mentoring program components, which we find to be more helpful than identifying specific features and ingredients. Although the focus is on the development of a new generation of investigators from diverse backgrounds, this template may also apply to mentoring programs for other investigators and for disciplines beyond HIV.

[Antibiotics: present and future].

PubMed

Bérdy, János

2013-04-14

The author discuss the up to date interpretation of the concept of antibiotics and antibiotic research, as well as the present role of various natural, semisynthetic and synthetic antibiotic compounds in various areas of the human therapy. The origin and the total number of all antibiotics and applied antibiotics in the practice, as well as the bioactive microbial metabolites (antibiotics) in other therapeutical, non-antibiotic fields (including agriculture) are also reviewed. The author discusses main problems, such as increasing (poly)resistance, virulence of pathogens and the non-scientific factors (such as a decline of research efforts and their sociological, economic, financial and regulatory reasons). A short summary of the history of Hungarian antibiotic research is also provided. The author briefly discusses the prospects in the future and the general advantages of the natural products over synthetic compounds. It is concluded that new approaches for the investigation of the unlimited possibilities of the living world are necessary. The discovery of new types or simply neglected (micro)organisms and their biosynthetic capabilities, the introduction of new biotechnological and genetic methods (genomics, metagenom, genome mining) are absolutely required in the future.

Mortality investigation of workers in an electromagnetic pulse test program.

PubMed

Muhm, J M

1992-03-01

A standardized mortality ratio study of 304 male employees of an electromagnetic pulse (EMP) test program was conducted. Outcomes were ascertained by two methods: the World Health Organization's underlying cause of death algorithm; and the National Center for Health Statistics' algorithm to identify multiple listed causes of death. In the 3362 person-years of follow-up, there was one underlying cause of death due to leukemia compared with with 0.2 expected (standard mortality ratio [SMR] = 437, 95% confidence interval [CI] = 11-2433), and two multiple listed causes of death due to leukemia compared with 0.3 expected (SMR = 775, 95% CI = 94-2801). Although the study suggested an association between death due to leukemia and employment in the EMP test program, firm conclusions could not be drawn because of limitations of the study. The findings warrant further investigation in an independent cohort.

Future changes in large-scale transport and stratosphere-troposphere exchange

NASA Astrophysics Data System (ADS)

Abalos, M.; Randel, W. J.; Kinnison, D. E.; Garcia, R. R.

2017-12-01

Future changes in large-scale transport are investigated in long-term (1955-2099) simulations of the Community Earth System Model - Whole Atmosphere Community Climate Model (CESM-WACCM) under an RCP6.0 climate change scenario. We examine artificial passive tracers in order to isolate transport changes from future changes in emissions and chemical processes. The model suggests enhanced stratosphere-troposphere exchange in both directions (STE), with decreasing tropospheric and increasing stratospheric tracer concentrations in the troposphere. Changes in the different transport processes are evaluated using the Transformed Eulerian Mean continuity equation, including parameterized convective transport. Dynamical changes associated with the rise of the tropopause height are shown to play a crucial role on future transport trends.

Management of menopause-associated vasomotor symptoms: Current treatment options, challenges and future directions

PubMed Central

Pachman, Deirdre R; Jones, Jason M; Loprinzi, Charles L

2010-01-01

Hot flashes are one of the most common and distressing symptoms associated with menopause, occurring in more than 75% of postmenopausal women. They are especially problematic in breast cancer patients since some breast cancer therapies can induce hot flashes. For mild hot flashes, it is proposed that behavioral modifications are the first step in management. Hormonal therapies, including estrogens and progestogens, are the most well known effective agents in relieving hot flashes; however, the safety of these agents is controversial. There is an increasing amount of literature on nonhormonal agents for the treatment of hot flashes. The most promising data regard newer antidepressant agents such as venlafaxine, which reduces hot flashes by about 60%. Gabapentin is another nonhormonal agent that is effective in reducing hot flashes. While many complimentary therapies, including phytoestrogens, black cohosh, and dehydroepiandrosterone, have been explored for the treatment of hot flashes; none can be recommended at this time. Furthermore, there is a lack of strong evidence to support exercise, yoga, or relaxation for the treatment of hot flashes. Paced respirations and hypnosis appear to be promising enough to warrant further investigation. Another promising nonpharmacological therapy, currently under investigation, involves a stellate ganglion block. PMID:21072305

U.S. and Israeli Young Women's Future Perceptions

ERIC Educational Resources Information Center

Michael, Rinat; Kim, TaeSun; Hutchison, Ashley; Cinamon, Rachel Gali; Gerstein, Lawrence H.; Park, Juno; Choi, Yuri; Bellare, Yamini; Collins, Rachael

2017-01-01

The current study investigated the content of future perceptions among 47 U.S. women and 48 Israeli women. Thematic analysis was used to explore participants' qualitative responses. Women's responses covered a wide range of topics, and were categorized into ten key themes: (a) work, (b) family/relationships, (c) property, (d) residence, (e)…

Simulation of an ensemble of future climate time series with an hourly weather generator

NASA Astrophysics Data System (ADS)

Caporali, E.; Fatichi, S.; Ivanov, V. Y.; Kim, J.

2010-12-01

There is evidence that climate change is occurring in many regions of the world. The necessity of climate change predictions at the local scale and fine temporal resolution is thus warranted for hydrological, ecological, geomorphological, and agricultural applications that can provide thematic insights into the corresponding impacts. Numerous downscaling techniques have been proposed to bridge the gap between the spatial scales adopted in General Circulation Models (GCM) and regional analyses. Nevertheless, the time and spatial resolutions obtained as well as the type of meteorological variables may not be sufficient for detailed studies of climate change effects at the local scales. In this context, this study presents a stochastic downscaling technique that makes use of an hourly weather generator to simulate time series of predicted future climate. Using a Bayesian approach, the downscaling procedure derives distributions of factors of change for several climate statistics from a multi-model ensemble of GCMs. Factors of change are sampled from their distributions using a Monte Carlo technique to entirely account for the probabilistic information obtained with the Bayesian multi-model ensemble. Factors of change are subsequently applied to the statistics derived from observations to re-evaluate the parameters of the weather generator. The weather generator can reproduce a wide set of climate variables and statistics over a range of temporal scales, from extremes, to the low-frequency inter-annual variability. The final result of such a procedure is the generation of an ensemble of hourly time series of meteorological variables that can be considered as representative of future climate, as inferred from GCMs. The generated ensemble of scenarios also accounts for the uncertainty derived from multiple GCMs used in downscaling. Applications of the procedure in reproducing present and future climates are presented for different locations world-wide: Tucson (AZ

Investigation of factors affecting the heater wire method of calibrating fine wire thermocouples

NASA Technical Reports Server (NTRS)

Keshock, E. G.

1972-01-01

An analytical investigation was made of a transient method of calibrating fine wire thermocouples. The system consisted of a 10 mil diameter standard thermocouple (Pt, Pt-13% Rh) and an 0.8 mil diameter chromel-alumel thermocouple attached to a 20 mil diameter electrically heated platinum wire. The calibration procedure consisted of electrically heating the wire to approximately 2500 F within about a seven-second period in an environment approximating atmospheric conditions at 120,000 feet. Rapid periodic readout of the standard and fine wire thermocouple signals permitted a comparison of the two temperature indications. An analysis was performed which indicated that the temperature distortion at the heater wire produced by the thermocouple junctions appears to be of negligible magnitude. Consequently, the calibration technique appears to be basically sound, although several practical changes which appear desirable are presented and discussed. Additional investigation is warranted to evaluate radiation effects and transient response characteristics.

How adolescents construct their future: the effect of loneliness on future orientation.

PubMed

Seginer, Rachel; Lilach, Efrat

2004-12-01

This study examined the effect of loneliness, gender, and two dimensions of prospective life domains on adolescent future orientation. Future orientation was studied in four prospective domains: social relations, marriage and family, higher education and work and career. These domains are described in terms of two dimensions: theme (relational vs. instrumental) and distance (near vs. distant future). Data collected from Israeli Jewish adolescents (11th graders) were analysed by repeated measures ANOVAs and ANCOVAs (covariate: depressive experiences) for seven future orientation variables: value, expectance, control (motivational variables), hopes, fears (cognitive representation variables), exploration, commitment (behavioural variables). As predicted, lonely adolescents scored lower than socially embedded adolescents on future orientation variables applied to the relational and near future domains and lonely boys scored lower than lonely girls. However, effects were found only on the three future orientation motivational variables and not on the cognitive representation and behavioural variables. Contrary to prediction controlling for the effect of depressive experiences did not reduce the effect of loneliness on the future orientation variables, but reduced the tendency of adolescents to score higher on all future orientation variables in the instrumental than in the relational prospective domains. The contribution of these findings to the understanding of adolescent loneliness and future orientation was discussed and directions for future research were suggested.

Warrant Officer Senior Course WOSC Evaluation.

DTIC Science & Technology

1981-07-01

Finance 2 Principles of Economics II I Managerial Accounting (Graduate) I Marketing Management (Graduate) I Principles of Biology 2 Number of Students...34? ’)rocesi, T he 3’’?~- ’ ADP.’- Gon~wcrslo, i li tAdniastr: ja-ln Cili- an Porsonel Management 7 Sl1pplV 0-: --i i 2 Li Support Structlirk! (,r,. ral L.~ i...ing, a ontapuivar* d Ar,2a Soviet Irw CiS Class 81-1 SUBJECT HOURS Techniques of Management I Transactional Analysis 2 Economic Approach and Linear

Warrant Officer Orientation Course (WOOC) Evaluation

DTIC Science & Technology

1981-10-01

Army Mainte- nance Management System, Security Awareness, Organizational Effectiveness, Introduction to Management , Enlisted Personnel Management...Orientation Introduction to Management Professional Ethics USA Officer Evaluation Reporting System (OES) Military Correspondence Military...Organizational Effectiveness, Introduction to Management , Enlisted Personnal Management System, and The Army Functional Files System and The Army

Tuberculosis-related stigma leading to an incomplete contact investigation in a low-incidence country.

PubMed

Faccini, M; Cantoni, S; Ciconali, G; Filipponi, M T; Mainardi, G; Marino, A F; Senatore, S; Codecasa, L R; Ferrarese, M; Gesu, G; Mazzola, E; Filia, A

2015-10-01

A contact investigation following a case of infectious tuberculosis (TB) reported in a call centre in Milan (Italy) led to the identification of three additional cases that had occurred in employees of the same workplace during the previous 5 years, one of whom was the probable source case. Thirty-three latent infections were also identified. At the time of diagnosis, the source case, because of fear of stigma related to TB, claimed to be unemployed and a contact investigation was not performed in the workplace. Cases were linked through genotyping of Mycobacterium tuberculosis. TB stigma has been described frequently, mainly in high-incidence settings, and is known to influence health-seeking behaviours and treatment adherence. The findings in this report highlight that TB-associated stigma may also lead to incomplete contact investigations. Little is known about the causes and impact of TB-related stigma in low-incidence countries and this warrants further exploration. Research is also needed to evaluate the effectiveness of specific interviewing techniques and training interventions for staff in reducing feelings of stigma in TB patients. Finally, the outbreak emphasizes the importance of integrating routine contact investigations with genotyping.

The ISS flight of Richard Garriott: a template for medicine and science investigation on future spaceflight participant missions.

PubMed

Jennings, Richard T; Garriott, Owen K; Bogomolov, Valery V; Pochuev, Vladimir I; Morgun, Valery V; Garriott, Richard A

2010-02-01

A total of eight commercial spaceflight participants have launched to the International Space Station (ISS) on Soyuz vehicles. Based on an older mean age compared to career astronauts and an increased prevalence of medical conditions, spaceflight participants have provided the opportunity to learn about the effect of space travel on crewmembers with medical problems. The 12-d Soyuz TMA-13/12 ISS flight of spaceflight participant Richard Garriott included medical factors that required preflight intervention, risk mitigation strategies, and provided the opportunity for medical study on-orbit. Equally important, Mr. Garriott conducted extensive medical, scientific, and educational payload operations during the flight. These included 7 medical experiments and a total of 15 scientific projects such as protein crystal growth, Earth observations/photography, educational projects with schools, and amateur radio. The medical studies included the effect of microgravity on immune function, sleep, bone loss, corneal refractive surgery, low back pain, motion perception, and intraocular pressure. The overall mission success resulted from non-bureaucratic agility in mission planning, cooperation with investigators from NASA, ISS, International Partners, and the Korean Aerospace Research Institute, in-flight support and leadership from a team with spaceflight and Capcom experience, and overall mission support from the ISS program. This article focuses on science opportunities that suborbital and orbital spaceflight participant flights offer and suggests that the science program on Richard Garriott's flight be considered a model for future orbital and suborbital missions. The medical challenges are presented in a companion article.

Future use of digital remote sensing data

NASA Technical Reports Server (NTRS)

Spann, G. W.; Jones, N. L.

1978-01-01

Users of remote sensing data are increasingly turning to digital processing techniques for the extraction of land resource, environmental, and natural resource information. This paper presents the results of recent and ongoing research efforts sponsored, in part, by NASA/Marshall Space Flight Center on the current uses of and future needs for digital remote sensing data. An ongoing investigation involves a comprehensive survey of capabilities for digital Landsat data use in the Southeastern U.S. Another effort consists of an evaluation of future needs for digital remote sensing data by federal, state, and local governments and the private sector. These needs are projected into the 1980-1985 time frame. Furthermore, the accelerating use of digital remote sensing data is not limited to the U.S. or even to the developed countries of the world.

Envisioning the times of future events: The role of personal goals.

PubMed

Ben Malek, Hédi; Berna, Fabrice; D'Argembeau, Arnaud

2018-05-25

Episodic future thinking refers to the human capacity to imagine or simulate events that might occur in one's personal future. Previous studies have shown that personal goals guide the construction and organization of episodic future thoughts, and here we sought to investigate the role of personal goals in the process of locating imagined events in time. Using a think-aloud protocol, we found that dates were directly accessed more frequently for goal-related than goal-unrelated future events, and the goal-relevance of events was a significant predictor of direct access to temporal information on a trial-by-trial basis. Furthermore, when an event was not directly dated, references to anticipated lifetime periods were more frequently used as a strategy to determine when a goal-related event might occur. Together, these findings shed new light on the mechanisms by which personal goals contribute to the location of imagined events in future times. Copyright © 2018 Elsevier Inc. All rights reserved.

Nutrition and Gaelic football: review, recommendations, and future considerations.

PubMed

Beasley, Kevin J

2015-02-01

Gaelic football is the second most popular team sport in Ireland in terms of participation. However, very little research exists on the nutritional considerations for elite male Gaelic footballers. Gaelic football is an intermittent type field game played by two teams of fifteen players. Although amateurs, elite players may train and compete 4-5 times per week and may play for several teams. Research suggests that elite footballers are similar anthropometrically and in fitness to professional soccer players. Work-rate analysis shows that footballers experience longer durations of high-intensity (HI) activity (5-7s) and shorter rest durations than soccer players. Recent data suggests that half-forward/backs perform a greater amount of HI work during games than players in other positions. Fatigue is apparent between the first and second halves and the first and fourth quarters. The limited amount of nutritional studies conducted implies that footballers may be deficient in energy intake and may be at the lower end of recommended carbohydrate intakes to support training. A wide variety of sweat rates have been measured during training, demonstrating the importance of individual hydration strategies. Ergogenic aids such as creatine and caffeine may prove beneficial to performance, although data are extrapolated from other sports. Due to the lack of research in Gaelic football, further population specific studies are required. Future areas of research on the impact of nutrition on Gaelic football performance are examined. In particular, the creation of a test protocol mimicking the activity patterns and intensity of a Gaelic football game is warranted.

Materialism, Stress and Health Behaviors among Future Educators

ERIC Educational Resources Information Center

Brouskeli, Vasiliki; Loumakou, Maria

2014-01-01

In this study we investigated materialism among future educators and its relationship with stress and a number of health behaviors. Participants were 228 students (Mean = 20.64 years of age, S.D = 2.571) of the Department of Education Sciences in Early Childhood of the University of Thrace, Greece. The instrument consisted of a short form of the…

The Role of Future Time Perspective in Psychological Contracts: A Study among Older Workers

ERIC Educational Resources Information Center

Bal, P. Matthijs; Jansen, Paul G. W.; van der Velde, Mandy E. G.; de Lange, Annet H.; Rousseau, Denise M.

2010-01-01

Using a sample of post-retirement workers (N = 176), this study investigated the role of future time perspective (FTP) in psychological contracts. The study aimed to test: (i) whether future time perspective is related to employer psychological contract fulfillment and (ii) whether it moderates relations between psychological contract fulfillment…

Cyberlearning Community Report: The State of Cyberlearning and The Future of Learning with Technology

ERIC Educational Resources Information Center

Ahn, June; Asbell-Clarke, Jodi; Berland, Matthew; Chase, Catherine; Enyedy, Noel; Fusco, Judith; Gardner, Shari; Grover, Shuchi; Halverson, Erica; Jona, Kemi; Lane, H. Chad; Martin, Wendy; Mercier, Emma; Moher, Tom; Ogan, Amy; Pinkard, Nichole; Polman, Joseph; Roschelle, Jeremy; Schank, Patricia; Taylor, Katie Headrick; Wilkerson, Michelle; Worsley, Marcelo

2017-01-01

Cyberlearning researchers envision and investigate the future of learning with technology. As of summer 2017, the Cyberlearning and Future Learning Technologies (CFTL) program of the National Science Foundation (NSF) had made 279 research grant awards. In addition, several hundred other NSF research projects have cyberlearning themes. Many of…

Investigation of conjugate circular arcs in rocket nozzle contour design

NASA Astrophysics Data System (ADS)

Schomberg, K.; Olsen, J.; Neely, A.; Doig, G.

2018-05-01

The use of conjugate circular arcs in rocket nozzle contour design has been investigated by numerically comparing three existing sub-scale nozzles to a range of equivalent arc-based contour designs. Three performance measures were considered when comparing nozzle designs: thrust coefficient, nozzle exit wall pressure, and a transition between flow separation regimes during the engine start-up phase. In each case, an equivalent arc-based contour produced an increase in the thrust coefficient and exit wall pressure of up to 0.4 and 40% respectively, in addition to suppressing the transition between a free and restricted shock separation regime. A general approach to arc-based nozzle contour design has also been presented to outline a rapid and repeatable process for generating sub-scale arc-based contours with an exit Mach number of 3.8-5.4 and a length between 60 and 100% of a 15° conical nozzle. The findings suggest that conjugate circular arcs may represent a viable approach for producing sub-scale rocket nozzle contours, and that a further investigation is warranted between arc-based and existing full-scale rocket nozzles.

Risk of breast cancer after a diagnosis of ovarian cancer in BRCA mutation carriers: Is preventive mastectomy warranted?

PubMed

McGee, Jacob; Giannakeas, Vasily; Karlan, Beth; Lubinski, Jan; Gronwald, Jacek; Rosen, Barry; McLaughlin, John; Risch, Harvey; Sun, Ping; Foulkes, William D; Neuhausen, Susan L; Kotsopoulos, Joanne; Narod, Steven A

2017-05-01

Preventive breast surgery and MRI screening are offered to unaffected BRCA mutation carriers. The clinical benefit of these two modalities has not been evaluated among mutation carriers with a history of ovarian cancer. Thus, we sought to determine whether or not BRCA mutation carriers with ovarian cancer would benefit from preventive mastectomy or from MRI screening. First, the annual mortality rate for ovarian cancer patients was estimated for a cohort of 178 BRCA mutation carriers from Ontario, Canada. Next, the actuarial risk of developing breast cancer was estimated using an international registry of 509 BRCA mutation carriers with ovarian cancer. A series of simulations was conducted to evaluate the reduction in the probability of death (from all causes) associated with mastectomy and with MRI-based breast surveillance. Cox proportional hazards models were used to evaluate the impacts of mastectomy and MRI screening on breast cancer incidence as well as on all-cause mortality. Twenty (3.9%) of the 509 patients developed breast cancer within ten years following ovarian cancer diagnosis. The actuarial risk of developing breast cancer at ten years post-diagnosis, conditional on survival from ovarian cancer and other causes of mortality was 7.8%. Based on our simulation results, among all BRCA mutation-carrying patients diagnosed with stage III/IV ovarian cancer at age 50, the chance of dying before age 80 was reduced by less than 1% with MRI and by less than 2% with mastectomy. Greater improvements in survival with MRI or mastectomy were observed for women who had already survived 10years after ovarian cancer, and for women with stage I or II ovarian cancer. Among BRCA mutation-carrying ovarian cancer patients without a personal history of breast cancer, neither preventive mastectomy nor MRI screening is warranted, except for those who have survived ovarian cancer without recurrence for ten years and for those with early stage ovarian cancer. Copyright © 2017

Nonmelanoma skin cancer in mountain guides: high prevalence and lack of awareness warrant development of evidence-based prevention tools.

PubMed

Zink, Alexander; Koch, Elisabeth; Seifert, Florian; Rotter, Markus; Spinner, Christoph D; Biedermann, Tilo

2016-01-01

Nonmelanoma skin cancer (NMSC) is the most common cancer in Switzerland and Europe. The main causative factor is exposure to ultraviolet radiation, which puts outdoor workers in general at a higher risk of developing NMSC than indoor workers. However, few studies have clinically examined the risk of developing NMSC to outdoor workers, especially mountain guides. We aimed to investigate the prevalence of NMSC and corresponding precancerous lesions, and the associated risk behaviour of mountain and ski guides in order to develop future prevention programmes. We conducted a cross-sectional study including mountain and ski guides from southern Germany, who underwent a full-body skin check-up by a dermatologist. We assessed their NMSC awareness and risk behaviour using a paper-based questionnaire. Of the 62 state-certified mountain and ski guides (55 men, 7 women; mean age 52.9 ± 13.4 years) included in this study, 27 (43.5%) were diagnosed with NMSC or its premalignant stages. In addition, 59.7% of the participants expressed the opinion that their protection from ultraviolet radiation exposure needs to be improved; 83.6% requested further information on NMSC, and 48.5% had never undergone a skin check-up or consulted a dermatologist before. Mountain and ski guides are at a high risk for developing NMSC. Their unmet medical needs indicate an underestimation of NMSC prevalence, which is usually based on reports by insurance companies, and offer the chance for developing evidence-based awareness and prevention tools that can be promoted to individuals with other outdoor jobs.

A pilot investigation in constructing crisis communications: what leads to best practice?

PubMed

Firestone, Rachel M; Everly, George S

2013-01-01

Crisis communications can play an important role in mitigating, or exacerbating, the psychological and behavioral reactions to critical incidents and disasters. Effective crisis communications can serve to mitigate anxiogenesis and direct rapid and focused rescue, recovery, and rehabilitative operations. Ambiguous and/or deceptive communications can serve to worsen mental health reactions and delay operational response and recovery (Everly, Strouse, & Everly, 2010). It seems, therefore, that inquiry into the content of acute crisis communications would be warranted Said more simply, given limited time, cryptic messaging in social media, and the "sound bite" mentality that seems to govern news dissemination, it is important to identify the most important content to convey in the wake of critical incidents and disasters. This paper reports on a pilot investigation into "best practices" for the construction of acute crisis communications.

Treatment of adult and pediatric high-grade gliomas with Withaferin A: antitumor mechanisms and future perspectives.

PubMed

Marlow, Megan M; Shah, Sumedh S; Véliz, Eduardo A; Ivan, Michael E; Graham, Regina M

2017-01-01

Resistance mechanisms employed by high-grade gliomas allow them to successfully evade current standard treatment of chemotherapy and radiation treatment. Withaferin A (WA), utilized in Ayurvedic medicine for centuries, is attracting attention for its antitumor capabilities. Here we review pertinent literature on WA as a high-grade glioma treatment, and discuss the cancerous mechanisms it affects. WA is relatively nontoxic and has shown potential in crossing the blood-brain barrier. WA prevents p53 alterations and inactivates overexpressed MDM2 through ARF and ROS production. Furthermore, WA upregulates Bax, inducing mitochondrial death cascades, inhibits mutated Akt, mTOR, and NF-κB pathways, and inhibits angiogenesis in tumors. Therapy with WA for high-grade gliomas is supported through the literature. Further investigation is warranted and encouraged to fully unearth its abilities against malignant gliomas.

Current and Future Status of Diversity in Ophthalmologist Workforce.

PubMed

Xierali, Imam M; Nivet, Marc A; Wilson, M Roy

2016-09-01

medically underserved areas (P < .001). Women and URM groups remain underrepresented in the ophthalmologist workforce despite an available pool of medical students. Given the prevalent racial and ethnic disparities in eye care and an increasingly diverse society, future research and training efforts that increase the level of diversity among medical students and residents seems warranted.

Renewable Electricity Futures: Exploration of Up to 80% Renewable Electricity Penetration in the United States (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, M.; DeMeo, E.; Hostick, D.

2013-04-01

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

"On solid ground": family and school connectedness promotes adolescents' future orientation.

PubMed

Crespo, Carla; Jose, Paul E; Kielpikowski, Magdalena; Pryor, Jan

2013-10-01

The present study investigated the role of connectedness to the family and school contexts on future orientation of New Zealand adolescents. Participants were 1774 young people (51.9% female) aged between 9 and 16 years at time 1 of the study, who reported their connectedness to family and school and their perceptions of future orientation at three times of measurement one year apart. Structural equation modelling was used to test the combined role of family and school connectedness on future orientation over time. Findings supported a multiple mediation model in that adolescents' connectedness to family and school predicted more positive perceptions of future orientation both directly and indirectly via the effect of the context variables on each other. Copyright © 2013 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Proceedings of the First Biennial Space Biomedical Investigators' Workshop

NASA Technical Reports Server (NTRS)

1999-01-01

The First Biennial Space Biomedical Investigators' Workshop, held January 11-13, 1999, was unique in that it assembled, for the first time, a broad cross section of NASA-funded biomedical researchers to present the current status of their projects and their plans for future investigations. All principal investigators with active, or recently-completed ground-based projects in NASA's Biomedical Research and Countermeasures Program that were funded through NASA's Office of Life and Microgravity Sciences and Applications were invited. Included were individual investigators funded through NASA Research Announcements, investigators with NASA Specialized Centers of Research and Training, investigators with the recently established National Space Biomedical Research Institute (NSBRI), and NASA civil servant investigators. Seventy-seven percent of all eligible projects were presented at the workshop. Thus, these Proceedings should provide a useful snapshot of the status of NASA-funded space biomedical research as of January 1999. An important workshop objective was to achieve free and open communication among the presenting investigators. Therefore, presentation of new and incomplete results, as well as hypotheses and ideas for future research, was encouraged. Comments and constructive criticisms from the presenters' colleagues were also encouraged. These ground rules resulted in many lively and useful discussions, during both the presentation sessions and informal evening gatherings and breaks.

Investigating a redesigned physics course for future elementary teachers

NASA Astrophysics Data System (ADS)

Fracchiolla, Claudia

There is a growing concern that the number of students graduating with a STEM major in the U.S. is insufficient to fill the growing demand in STEM careers. In order to fulfill that demand, it is important to increase student retention in STEM majors and also to attract more students to pursue careers in those areas. Previous research has indicated that children start losing interest in science at the elementary level because science is taught with a focus on learning vocabulary and ideas rather than learning through inquiry-based techniques. A factor that affects the quality of science education at the elementary level is the preparation of elementary teachers. Many elementary teachers feel unprepared to teach science because they lack adequate content knowledge as well as the pedagogical content knowledge (PCK) for teaching the subject. Previous studies of teacher preparation in science identified some areas with which pre-service teachers need assistance. One of these areas is understanding children's ideas of science. To address that issue, this dissertation investigates whether the use of an instructional approach that teaches physics phenomena along with an understanding of how children think about the physical phenomena promotes changes in students' knowledge of children's ideas and use of those ideas in instructional and assessment strategies. Results indicated that students who were explicitly exposed to knowledge of children's ideas more often incorporated those ideas into their own microteaching and demonstrated higher levels of sophistication of knowledge of children's ideas, instructional strategies, and assessment strategies that incorporated those ideas. This research explores an instructional model for blending physics content and pedagogical content knowledge.

NASA Future Forum

NASA Image and Video Library

2012-02-21

Jordan Hansell, chairman and CEO, NetJets Inc. talks during the NASA Future Forum panel titled "Importance of Technology, Science and Innovation for our Economic Future" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Michael Donovan, technology consultant, New Services Development, Hewlett-Packard Company talks during the NASA Future Forum panel titled "Importance of Technology, Science and Innovation for our Economic Future" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Laurie Leshin, dean of the School of Science, Rensselaer Polytechnic Institute, moderates the NASA Future Forum panel titled "Importance of Technology, Science and Innovation for our Economic Future" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

Future Changes in Major Stratospheric Warmings in CCMI Models

NASA Technical Reports Server (NTRS)

Ayarzaguena, B.; Langematz, U.; Polvani, L. M; Abalichin, J.; Akiyoshi, H.; Klekociuk, A.; Michou, M.; Morgenstern, O.; Oman, L.

2015-01-01

Major stratospheric warmings (MSWs) are one of the most important phenomena of wintertime Arctic stratospheric variability. They consist of a warming of the Arctic stratosphere and a deceleration of the polar night jet, triggered by an anomalously high injection of tropospheric wave activity into the stratosphere. Due to the relevance and the impact of MSWs on the tropospheric circulation, several model studies have investigated their potential responses to climate change. However, a wide range of results has been obtained, extending from a future increase in the frequency of MSWs to a decrease. These discrepancies might be explained by different factors such as a competition of radiative and dynamical contributors with opposite effects on the Arctic polar vortex, biases of models to reproduce the related processes, or the metric chosen for the identification of MSWs. In this study, future changes in wintertime Arctic stratospheric variability are examined in order to obtaina more precise picture of future changes in the occurrence of MSWs. In particular, transient REFC2 simulations of different CCMs involved in the Chemistry Climate Model Initiative (CCMI) are used. These simulations extend from 1960 to 2100 and include forcings by halogens and greenhouse gases following the specifications of the CCMI-REF-C2 scenario. Sea surface temperatures (SSTs) and sea-ice distributions are either prescribed from coupled climate model integrations or calculated internally in the case of fully coupled atmosphere-ocean CCMs. Potential changes in the frequency and main characteristics of MSWs in the future are investigated with special focus on the dependence of the results on the criterion for the identification of MSWs and the tropospheric forcing of these phenomena.

Prediction of future hepatocellular carcinoma incidence in moderate to heavy alcohol drinkers with the FIB-4 liver fibrosis index.

PubMed

Suh, Beomseok; Yun, Jae Moon; Park, Sehhoon; Shin, Dong Wook; Lee, Tae Hoon; Yang, Hyung-Kook; Ahn, Eunmi; Lee, Hyejin; Park, Jin Ho; Cho, BeLong

2015-11-01

Although heavy alcoholics are at heightened risk for hepatocellular carcinoma (HCC), there are no guidelines that recommend HCC screening for heavy alcoholics. This study investigated FIB-4, a noninvasive and easily applicable liver fibrosis index, as a risk factor for HCC incidence among alcohol drinkers without viral hepatitis. This retrospective cohort study included 6661 generally healthy adults who were 30 years old or older, did not have chronic viral hepatitis, and visited Seoul National University Hospital for a general, routine health evaluation. The future HCC incidence was determined from National Health Insurance medical service claims data (median follow-up, 6.2 years). With adjustments for age, sex, body mass index, smoking, and alcohol, compared with subjects with FIB-4 values less 1.00, subjects with FIB-4 values greater than or equal to 1.75 and less than 2.10 and subjects with FIB-4 values greater than or equal to 2.10 had adjusted hazard ratios (aHRs) of 5.18 (95% confidence interval [CI], 1.12-24.00) and 13.63 (95% CI, 3.77-49.33), respectively, for HCC incidence. This was heightened in subjects who drank more 30 g of alcohol per day: the aHRs were 8.39 (95% CI, 1.28-54.87) and 16.58 (95% CI, 3.87-71.04), respectively. FIB-4 was shown to have a higher predictive value for HCC incidence than ultrasonographically detected liver cirrhosis (C-index, 0.665 vs 0.527; P = .044). High FIB-4 is a risk factor with a high predictive value for HCC incidence, especially among moderate to heavy alcoholics (>30 g/d). FIB-4 is a readily available and probably cost-effective clinical tool with potential value for identifying subpopulations of alcoholics at particularly high risk who would benefit from regular HCC screening. Further investigations are warranted to validate our results; nonetheless, our study suggests that FIB-4 may be useful in HCC screening among alcoholics. © 2015 American Cancer Society.

Anticipating Their Future: Adolescent Values for the Future Predict Adult Behaviors

ERIC Educational Resources Information Center

Finlay, Andrea K.; Wray-Lake, Laura; Warren, Michael; Maggs, Jennifer

2015-01-01

Adolescent future values--beliefs about what will matter to them in the future--may shape their adult behavior. Utilizing a national longitudinal British sample, this study examined whether adolescent future values in six domains (i.e., family responsibility, full-time job, personal responsibility, autonomy, civic responsibility, and hedonistic…

Greening the Future

ERIC Educational Resources Information Center

Williamson, Norma Velia

2011-01-01

Because educators vicariously touch the future through their students, the author believes that they sometimes have the uncanny ability to see the future. One common future forecast is the phenomenal growth of green jobs in the emerging green economy, leading to the creation of the "Reach of the Sun" Solar Energy Academy at La Mirada…

Sex and Age Differences in Future Temporal Perspective.

ERIC Educational Resources Information Center

Grant, Edward; Sawler, Joyce

This study explored sex differences in the Future Temporal Perspectives (FTP) of children. The influences of age, social class and intelligence were also investigated, or FTP was generally believed to be affected by them. Subjects were 96 boys and 96 girls, selected from 26 schools in Nova Scotia, from three age groups: 9.6-11.0, 12.0-13.6, and…

Opportunities for future supernova studies of cosmic acceleration.

PubMed

Weller, J; Albrecht, A

2001-03-05

We investigate the potential of a future supernova data set, as might be obtained by the proposed SNAP satellite, to discriminate among different "dark energy" theories that describe an accelerating Universe. We find that many such models can be distinguished with a fit to the effective pressure-to-density ratio w of this energy. More models can be distinguished when the effective slope dw/dz of a changing w is also fit, but only if our knowledge of the current mass density Omega(m) is improved. We investigate the use of "fitting functions" to interpret luminosity distance data from supernova searches.

In vitro activities of 14 antibiotics against 100 human isolates of Yersinia pestis from a southern African plague focus.

PubMed Central

Frean, J A; Arntzen, L; Capper, T; Bryskier, A; Klugman, K P

1996-01-01

A limited repertoire of antimicrobial agents is currently in use for the treatment of plague. We investigated the in vitro activities of some newer antimicrobial agents against Yersinia pestis. Among the injectable agents tested, cefotaxime was the most active, and among the oral agents, both levofloxacin and ofloxacin were highly active, with MICs at which 90% of isolates are inhibited of < 0.03 microgram/ml. the susceptibilities to the ketolide RU004 and the penem faropenem warrant attention. The enhanced activities of quinolones against Y. pestis suggest that these agents should be further investigated for the treatment of human plague in the future. PMID:8913481

NASA Future Forum

NASA Image and Video Library

2012-02-21

Ron Sega, Vice president and enterprise executive for Energy and the Environment, The Ohio State University and Colorado State University talks during the NASA Future Forum panel titled "Importance of Technology, Science and Innovation for our Economic Future" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

FCS Technology Investigation Overview

NASA Technical Reports Server (NTRS)

Budinger, James; Gilbert, Tricia

2007-01-01

This working paper provides an overview of the Future Communication Study (FCS) technology investigation progress. It includes a description of the methodology applied to technology evaluation; evaluation criteria; and technology screening (down select) results. A comparison of screening results with other similar technology screening activities is provided. Additional information included in this working paper is a description of in-depth studies (including characterization of the L-band aeronautical channel; L-band deployment cost assessment; and performance assessments of candidate technologies in the applicable aeronautical channel) that have been conducted to support technology evaluations. The paper concludes with a description on-going activities leading to conclusion of the technology investigation and the development of technology recommendations.

Mexican American Seventh Graders' Future Work and Family Plans: Associations with Cultural Experiences and Adjustment

ERIC Educational Resources Information Center

Cansler, Emily; Updegraff, Kimberly A.; Simpkins, Sandra D.

2012-01-01

We describe Mexican American seventh graders' expectations for future work and family roles and investigate links between patterns of future expectations and adolescents' cultural experiences and adjustment. Adolescents participated in home interviews and a series of seven nightly phone calls. Five unique patterns of adolescents' future…

Pathogenesis and Prediction of Future Rheumatoid Arthritis

DTIC Science & Technology

2016-10-01

AWARD NUMBER: W81XWH-13-1-0408 TITLE: Pathogenesis and Prediction of Future Rheumatoid Arthritis PRINCIPAL INVESTIGATOR: Kevin D. Deane, MD/PhD...SUBTITLE 5a. CONTRACT NUMBER Pathogenesis and Prediction of Rheumatoid Arthritis 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...preclinical period of rheumatoid arthritis (RA) development that is characterized by abnormalities of the immune system prior to the onset of the

Anticipating Their Future: Adolescent Values for the Future Predict Adult Behaviors

PubMed Central

Finlay, Andrea; Wray-Lake, Laura; Warren, Michael; Maggs, Jennifer L.

2014-01-01

Adolescent future values – beliefs about what will matter to them in the future – may shape their adult behavior. Utilizing a national longitudinal British sample, this study examined whether adolescent future values in six domains (i.e., family responsibility, full-time job, personal responsibility, autonomy, civic responsibility, and hedonistic privilege) predicted adult social roles, civic behaviors, and alcohol use. Future values positively predicted behaviors within the same domain; fewer cross-domain associations were evident. Civic responsibility positively predicted adult civic behaviors, but negatively predicted having children. Hedonistic privilege positively predicted adult alcohol use and negatively predicted civic behaviors. Results suggest that attention should be paid to how adolescents are thinking about their futures due to the associated links with long-term social and health behaviors. PMID:26279595

Assessing Risk for Future Firearms Violence in Young People Who Present to ED.

PubMed

2017-06-01

A new clinical index tool designed specifically for the emergency environment predicts the risk for future firearms violence in young people 14-24 years of age. The approach employs a brief, 10-point instrument that can be administered in one to two minutes, according to investigators. They also note that while the tool is based on data from a single ED in Flint, Ml, the tool should be applicable to urban EDs in regions that have similar characteristics. To create the tool, investigators used data from the Flint Youth Injury Study, an investigation of a group of patients 14-24 years of age who reported using drugs in the previous six months and accessed care at a Level I trauma center. Using a machine learning classification approach, investigators combed through the data, finding that the most predictive factors for firearm violence could be categorized into four domains: peer and partner violence victimization, community violence exposure, peer/family influences, and fighting. Ideally, investigators note the tool will be employed along with interventions targeted toward patients at high risk for future firearms violence.

A big data analysis of the relationship between future thinking and decision-making.

PubMed

Thorstad, Robert; Wolff, Phillip

2018-02-20

We use big data methods to investigate how decision-making might depend on future sightedness (that is, on how far into the future people's thoughts about the future extend). In study 1, we establish a link between future thinking and decision-making at the population level in showing that US states with citizens having relatively far future sightedness, as reflected in their tweets, take fewer risks than citizens in states having relatively near future sightedness. In study 2, we analyze people's tweets to confirm a connection between future sightedness and decision-making at the individual level in showing that people with long future sightedness are more likely to choose larger future rewards over smaller immediate rewards. In study 3, we show that risk taking decreases with increases in future sightedness as reflected in people's tweets. The ability of future sightedness to predict decisions suggests that future sightedness is a relatively stable cognitive characteristic. This implication was supported in an analysis of tweets by over 38,000 people that showed that future sightedness has both state and trait characteristics (study 4). In study 5, we provide evidence for a potential mechanism by which future sightedness can affect decisions in showing that far future sightedness can make the future seem more connected to the present, as reflected in how people refer to the present, past, and future in their tweets over the course of several minutes. Our studies show how big data methods can be applied to naturalistic data to reveal underlying psychological properties and processes.

An empirical study on information spillover effects between the Chinese copper futures market and spot market

NASA Astrophysics Data System (ADS)

Liu, Xiangli; Cheng, Siwei; Wang, Shouyang; Hong, Yongmiao; Li, Yi

2008-02-01

This study employs a parametric approach based on TGARCH and GARCH models to estimate the VaR of the copper futures market and spot market in China. Considering the short selling mechanism in the futures market, the paper introduces two new notions: upside VaR and extreme upside risk spillover. And downside VaR and upside VaR are examined by using the above approach. Also, we use Kupiec’s [P.H. Kupiec, Techniques for verifying the accuracy of risk measurement models, Journal of Derivatives 3 (1995) 73-84] backtest to test the power of our approaches. In addition, we investigate information spillover effects between the futures market and the spot market by employing a linear Granger causality test, and Granger causality tests in mean, volatility and risk respectively. Moreover, we also investigate the relationship between the futures market and the spot market by using a test based on a kernel function. Empirical results indicate that there exist significant two-way spillovers between the futures market and the spot market, and the spillovers from the futures market to the spot market are much more striking.

The Lactate Minimum Test: Concept, Methodological Aspects and Insights for Future Investigations in Human and Animal Models

PubMed Central

Messias, Leonardo H. D.; Gobatto, Claudio A.; Beck, Wladimir R.; Manchado-Gobatto, Fúlvia B.

2017-01-01

In 1993, Uwe Tegtbur proposed a useful physiological protocol named the lactate minimum test (LMT). This test consists of three distinct phases. Firstly, subjects must perform high intensity efforts to induce hyperlactatemia (phase 1). Subsequently, 8 min of recovery are allowed for transposition of lactate from myocytes (for instance) to the bloodstream (phase 2). Right after the recovery, subjects are submitted to an incremental test until exhaustion (phase 3). The blood lactate concentration is expected to fall during the first stages of the incremental test and as the intensity increases in subsequent stages, to rise again forming a “U” shaped blood lactate kinetic. The minimum point of this curve, named the lactate minimum intensity (LMI), provides an estimation of the intensity that represents the balance between the appearance and clearance of arterial blood lactate, known as the maximal lactate steady state intensity (iMLSS). Furthermore, in addition to the iMLSS estimation, studies have also determined anaerobic parameters (e.g., peak, mean, and minimum force/power) during phase 1 and also the maximum oxygen consumption in phase 3; therefore, the LMT is considered a robust physiological protocol. Although, encouraging reports have been published in both human and animal models, there are still some controversies regarding three main factors: (1) the influence of methodological aspects on the LMT parameters; (2) LMT effectiveness for monitoring training effects; and (3) the LMI as a valid iMLSS estimator. Therefore, the aim of this review is to provide a balanced discussion between scientific evidence of the aforementioned issues, and insights for future investigations are suggested. In summary, further analyses is necessary to determine whether these factors are worthy, since the LMT is relevant in several contexts of health sciences. PMID:28642717

Investigation of accidents within construction zones in Louisiana.

DOT National Transportation Integrated Search

1981-07-01

This investigation is to analyze construction and maintenance work zone accidents by reviewing accident data to determine if deficiencies exist and recommend possible corrective measures for future traffic control applications. To accomplish this, a ...

The future challenge for aeropropulsion

NASA Technical Reports Server (NTRS)

Rosen, Robert; Bowditch, David N.

1992-01-01

NASA's research in aeropropulsion is focused on improving the efficiency, capability, and environmental compatibility for all classes of future aircraft. The development of innovative concepts, and theoretical, experimental, and computational tools provide the knowledge base for continued propulsion system advances. Key enabling technologies include advances in internal fluid mechanics, structures, light-weight high-strength composite materials, and advanced sensors and controls. Recent emphasis has been on the development of advanced computational tools in internal fluid mechanics, structural mechanics, reacting flows, and computational chemistry. For subsonic transport applications, very high bypass ratio turbofans with increased engine pressure ratio are being investigated to increase fuel efficiency and reduce airport noise levels. In a joint supersonic cruise propulsion program with industry, the critical environmental concerns of emissions and community noise are being addressed. NASA is also providing key technologies for the National Aerospaceplane, and is studying propulsion systems that provide the capability for aircraft to accelerate to and cruise in the Mach 4-6 speed range. The combination of fundamental, component, and focused technology development underway at NASA will make possible dramatic advances in aeropropulsion efficiency and environmental compatibility for future aeronautical vehicles.

Constructing alternative futures

Treesearch

David N. Wear; Robert Huggett; John G. Greis

2013-01-01

The desired product of the Southern Forest Futures Project is a mechanism that will help southerners think about and prepare for future changes in their forests and the benefits they provide. Because any single projection of the world’s (or a region’s) biological, physical, and social systems has a high probability of being incorrect, the Futures Project instead...

[Novel concepts in biology of diffuse endocrine system: results and future investigations].

PubMed

Iaglov, V V; Iaglova, N V

2012-01-01

Diffuse endocrine system is a largest part of endocrine system of vertebrates. Recend findings showed that DES-cells are not neuroectodermal but have ectodermal, mesodermal, and entodermal ontogeny. The article reviews novel concept of diffuse endocrine system anatomy and physiology, functional role of DES hormones and poorly investigated aspects like DES-cell morphology, hormones secretion in normal and pathologic conditions. Further research of diffuse endocrine system has a great significance for biochemistry, morphology, and clinical medicine.

Factors Influencing Openness to Future Smoking among Nonsmoking Adolescents

ERIC Educational Resources Information Center

Seo, Dong-Chul; Torabi, Mohammad R.; Weaver, Amy E.

2008-01-01

Background: To investigate the correlates of youth tobacco use in terms of nonsmoking adolescents' openness to future smoking, a secondary analysis of the 2000 and 2004 Indiana Youth Tobacco Survey (IYTS) was conducted. Methods: A representative sample of 1416 public high school students in grades 9-12 and 1516 public middle school students in…

Onward to Outcomes in the School of the Future.

ERIC Educational Resources Information Center

Millea, Susan

This paper discusses the results of a study that investigated the effectiveness of a comprehensive school-based service program in Texas. The "School for the Future" project was a 5-year demonstration project in 4 Texas cities that was designed to develop and coordinate health and social services though targeted schools in low income,…

Memory underpinnings of future intentions: Would you like to see the sequel?

PubMed

Stragà, Marta; Del Missier, Fabio; Marcatto, Francesco; Ferrante, Donatella

2017-01-01

In two studies, we investigated the memory underpinnings of future intentions related to past hedonic experiences. Preceding research did not make clear whether the specific memory processes supporting the expression of intentions about the future involve global judgments of the past experience (general affective evaluations formed on-line) or judgments derived from the episodic recollection of the past. Adapting a correlational paradigm previously employed to study future intentions, and applying it to the experience of watching a movie, we comparatively tested the influence of global retrospective evaluations vs. episodic-derived evaluations on future intentions. In Study 1, in which the intentions involved a future experience that was very similar to an overall past one (e.g., seeing the movie sequel), the findings showed that participants relied only on global judgments to form future intentions. In Study 2, in which the global judgment on the past was less diagnostic because the future intentions referred to specific parts of the past experience (e.g., watching a movie centered on a minor character in the previously seen movie), the results indicated that relevant episodic memories provided an essential contribution to the prediction of future intentions. These findings are in agreement with the predictions of the accessibility-diagnosticity framework and they show that global judgments and episodic memories of a past experience contribute differentially to diverse kinds of future intentions.

Memory underpinnings of future intentions: Would you like to see the sequel?

PubMed Central

Marcatto, Francesco; Ferrante, Donatella

2017-01-01

In two studies, we investigated the memory underpinnings of future intentions related to past hedonic experiences. Preceding research did not make clear whether the specific memory processes supporting the expression of intentions about the future involve global judgments of the past experience (general affective evaluations formed on-line) or judgments derived from the episodic recollection of the past. Adapting a correlational paradigm previously employed to study future intentions, and applying it to the experience of watching a movie, we comparatively tested the influence of global retrospective evaluations vs. episodic-derived evaluations on future intentions. In Study 1, in which the intentions involved a future experience that was very similar to an overall past one (e.g., seeing the movie sequel), the findings showed that participants relied only on global judgments to form future intentions. In Study 2, in which the global judgment on the past was less diagnostic because the future intentions referred to specific parts of the past experience (e.g., watching a movie centered on a minor character in the previously seen movie), the results indicated that relevant episodic memories provided an essential contribution to the prediction of future intentions. These findings are in agreement with the predictions of the accessibility-diagnosticity framework and they show that global judgments and episodic memories of a past experience contribute differentially to diverse kinds of future intentions. PMID:28448567

Facing the future: Memory as an evolved system for planning future acts

PubMed Central

Klein, Stanley B.; Robertson, Theresa E.; Delton, Andrew W.

2013-01-01

All organisms capable of long-term memory are necessarily oriented toward the future. We propose that one of the most important adaptive functions of long-term episodic memory is to store information about the past in the service of planning for the personal future. Because a system should have especially efficient performance when engaged in a task that makes maximal use of its evolved machinery, we predicted that future-oriented planning would result in especially good memory relative to other memory tasks. We tested recall performance of a word list, using encoding tasks with different temporal perspectives (e.g., past, future) but a similar context. Consistent with our hypothesis, future-oriented encoding produced superior recall. We discuss these findings in light of their implications for the thesis that memory evolved to enable its possessor to anticipate and respond to future contingencies that cannot be known with certainty. PMID:19966234

Future Spacelift Requirements Study

NASA Technical Reports Server (NTRS)

1997-01-01

This study addresses future space applications and the derived requirements these potential applications will have on future spacelift systems. This NASA sponsored activity is a comprehensive study of potential missions including those of the military, civil, and commercial users. The study objectively evaluated the key architectural requirements for future launch systems. The results of this study are technical, economic, and policy analyses of future spacelift systems. It is intended to assist NASA and DOD decision-makers in planning technical investments and establishing policy for future U.S. spacelift systems.

"STEMulating" success factors: An investigation of the academic talents of successful Black male college graduates from STEM programs

NASA Astrophysics Data System (ADS)

Hendricks, Jill T.

This phenomenological research study explored the contributing factors experienced by Black males that epitomized their academic success in a STEM (Science, Technology, Engineering, and Mathematics) area of study. During this investigative project, eleven Black male students were interviewed to determine how they were able to successfully navigate and complete a STEM degree. The data was collected through a qualitative inquiry, which involved interviewing students and collecting the data and organizing their perspectives into common themes. The principal findings in this study suggest that Black males can excel when primary influential people establish high expectations and believe and encourage Black males to succeed by providing the essential educational support models requisite to warrant success; the Black male maintains and affirms a self-assured self-worth in himself; the Black male is exposed to these fields and professions early on in their educational quest to enable them to witness first hand powerful and productive opportunities and pathways to academic success; exposure to other Black successful male role models who can mentor and show positive proof that with effort, these fields can become a reality; increase in academic motivation and recommendations from educators and counselors who direct and guide students into and away from these rigorous career fields. An analysis of the students' individual stories gave a revealing look into the pathways of their consciousness, emotional growth, and perspectives about being a successful STEM major. This kind of insight can be a constructive diagnostic tool for students, educators, counselors, and administrators who want to motivate and influence future students to major in STEM fields of study.

Mapping letters from the future: exploring narrative processes of imagining the future.

PubMed

Sools, Anneke M; Tromp, Thijs; Mooren, Jan H

2015-03-01

This article uses Letters from the Future (a health promotion instrument) to explore the human capacity of imagining the future. From a narrative perspective, letters from the future are considered to be indicative of a variety of forms through which human beings construct and understand their future selves and worlds. This is consistent with an interpretive approach to understanding the human mind, which offers an alternative for the current dominant causal-explanatory approach in psychology. On the basis of qualitative analysis of 480 letters from the future, collected online from a diverse group of Dutch and German persons, we first identified five narrative processes operating in the letters: imagining, evaluating, orienting, expressing emotions and engaging in dialogue. Second, using comparative analysis, we identified six types of how these processes are organized in the letters as a whole. These types differ regarding functionality (which of the five processes was dominant); temporality (prospective, retrospective and present-oriented); the extent to which a path between present and future was described; and the vividness of the imagination. We suggest that these types can be used in narrative health practice as 'pathways' to locate where letter writers are on their path to imagine the future, rather than as a normative taxonomy. Future research should focus on how these pathways can be used to navigate to health and well-being. © The Author(s) 2015.

When does the future begin? Time metrics matter, connecting present and future selves.

PubMed

Lewis, Neil A; Oyserman, Daphna

2015-06-01

People assume they should attend to the present; their future self can handle the future. This seemingly plausible rule of thumb can lead people astray, in part because some future events require current action. In order for the future to energize and motivate current action, it must feel imminent. To create this sense of imminence, we manipulated time metric--the units (e.g., days, years) in which time is considered. People interpret accessible time metrics in two ways: If preparation for the future is under way (Studies 1 and 2), people interpret metrics as implying when a future event will occur. If preparation is not under way (Studies 3-5), they interpret metrics as implying when preparation should start (e.g., planning to start saving 4 times sooner for a retirement in 10,950 days instead of 30 years). Time metrics mattered not because they changed how distal or important future events felt (Study 6), but because they changed how connected and congruent their current and future selves felt (Study 7). © The Author(s) 2015.

Scientists Discover New Possibilities at Scientific Investigators Retreat | Poster

Cancer.gov

By Nancy Parrish, Staff Writer; photos by Richard Frederickson, Staff Photographer Scientists who attended the 2015 NCI Intramural Scientific Investigators Retreat on Jan. 13 had a chance to discuss research results with other investigators from across the National Cancer Institute. And this year, they could also explore new possibilities for the future of their research.

An Investigation for the Future Educators' Attitudes towards the Environmental Issues in the Context of Ecocentrism and Anthropocentrism

ERIC Educational Resources Information Center

Yumusak, Ahmet; Özbas, Serap; Sargin, Seyit Ahmet; Baltaci, Furkan

2016-01-01

In this study, it was revealed that the factors influencing the future educators' attitudes towards the environment. The survey was conducted between 2013-2014, on the freshman and the senior students studying in two different education faculties providing training within the boundaries of Turkish Cypriot. As a result, it has been found that…

NASA Future Forum

NASA Image and Video Library

2012-02-21

Sen. John Glenn delivers the closing remarks for NASA's Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

NASA Chief Technologist Mason Peck talks during the NASA Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

NASA Deputy Administrator Lori Garver speaks during the NASA Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

Back to the Consideration of Future Consequences Scale: time to reconsider?

PubMed

Rappange, David R; Brouwer, Werner B F; van Exel, N Job A

2009-10-01

The Consideration of Future Consequences (CFC) Scale is a measure of the extent to which individuals consider and are influenced by the distant outcomes of current behavior. In this study, the authors conducted factor analysis to investigate the factor structure of the 12-item CFC Scale. The authors found evidence for a multiple factor solution including one completely present-oriented factor consisting of all 7 present-oriented items, and one or two future-oriented factors consisting of the remaining future-oriented items. Further evidence indicated that the present-oriented factor and the 12-item CFC Scale perform similarly in terms of internal consistency and convergent validity. The structure and content of the future-oriented factor(s) is unclear. From the findings, the authors raise questions regarding the construct validity of the CFC Scale, the interpretation of its results, and the usefulness of the CFC scale in its current form in applied research.

A Future-Based Risk Assessment for the Survivability of Long Range Strike Systems

DTIC Science & Technology

2007-03-01

Aeronautics and Space Administration ( NASA ) investigated alternative futures to help generate a viable science strategy to address the future aerospace...World American World View ΔTeK World Power Grid Name 1 Global Exponential Dispersed DIGITAL CACOPHONY 2 Global Exponential Concentrated STAR TREK ...The United States has become the “United Kingdom of the Twenty-first Century.” 2.2.3. NASA Study (1997) In the NASA study, the National Research

Relations between Self Regulation, Future Time Perspective and the Delay of Gratification in University Students

ERIC Educational Resources Information Center

Avci, Suleyman

2013-01-01

The present study was conducted on 508 (331 female, 144 male) first grade university students in order to investigate the relations between self regulation, the future time perspectives, and the delay of gratification in the academic field. A future time perspective scale, an academic delay of gratification scale and a motivational strategies for…

Local-scale projections of coral reef futures and implications of the Paris Agreement

NASA Astrophysics Data System (ADS)

van Hooidonk, Ruben; Maynard, Jeffrey; Tamelander, Jerker; Gove, Jamison; Ahmadia, Gabby; Raymundo, Laurie; Williams, Gareth; Heron, Scott F.; Planes, Serge

2016-12-01

Increasingly frequent severe coral bleaching is among the greatest threats to coral reefs posed by climate change. Global climate models (GCMs) project great spatial variation in the timing of annual severe bleaching (ASB) conditions; a point at which reefs are certain to change and recovery will be limited. However, previous model-resolution projections (~1 × 1°) are too coarse to inform conservation planning. To meet the need for higher-resolution projections, we generated statistically downscaled projections (4-km resolution) for all coral reefs; these projections reveal high local-scale variation in ASB. Timing of ASB varies >10 years in 71 of the 87 countries and territories with >500 km2 of reef area. Emissions scenario RCP4.5 represents lower emissions mid-century than will eventuate if pledges made following the 2015 Paris Climate Change Conference (COP21) become reality. These pledges do little to provide reefs with more time to adapt and acclimate prior to severe bleaching conditions occurring annually. RCP4.5 adds 11 years to the global average ASB timing when compared to RCP8.5; however, >75% of reefs still experience ASB before 2070 under RCP4.5. Coral reef futures clearly vary greatly among and within countries, indicating the projections warrant consideration in most reef areas during conservation and management planning.

Local-scale projections of coral reef futures and implications of the Paris Agreement.

PubMed

van Hooidonk, Ruben; Maynard, Jeffrey; Tamelander, Jerker; Gove, Jamison; Ahmadia, Gabby; Raymundo, Laurie; Williams, Gareth; Heron, Scott F; Planes, Serge

2016-12-21

Increasingly frequent severe coral bleaching is among the greatest threats to coral reefs posed by climate change. Global climate models (GCMs) project great spatial variation in the timing of annual severe bleaching (ASB) conditions; a point at which reefs are certain to change and recovery will be limited. However, previous model-resolution projections (~1 × 1°) are too coarse to inform conservation planning. To meet the need for higher-resolution projections, we generated statistically downscaled projections (4-km resolution) for all coral reefs; these projections reveal high local-scale variation in ASB. Timing of ASB varies >10 years in 71 of the 87 countries and territories with >500 km 2 of reef area. Emissions scenario RCP4.5 represents lower emissions mid-century than will eventuate if pledges made following the 2015 Paris Climate Change Conference (COP21) become reality. These pledges do little to provide reefs with more time to adapt and acclimate prior to severe bleaching conditions occurring annually. RCP4.5 adds 11 years to the global average ASB timing when compared to RCP8.5; however, >75% of reefs still experience ASB before 2070 under RCP4.5. Coral reef futures clearly vary greatly among and within countries, indicating the projections warrant consideration in most reef areas during conservation and management planning.

Future heat stress arising from climate change on Iran's population health.

PubMed

Modarres, Reza; Ghadami, Mohammad; Naderi, Sohrab; Naderi, Mohammad

2018-04-05

Climate change-induced extreme heat events are becoming a major issue in different parts of the world, especially in developing countries. The assessment of regional and temporal past and future change in heat waves is a crucial task for public health strategies and managements. The historical and future heat index (HI) time series are investigated for temporal change across Iran to study the impact of global warming on public health. The heat index is calculated, and the nonparametric trend assessment is carried out for historical time series (1981-2010). The future change in heat index is also projected for 2020-2049 and 2070-2099 periods. A rise in the historical heat index and extreme caution conditions for summer and spring seasons for major parts of Iran are notable for historical (1981-2010) series in this study. Using different climate change scenarios shows that heat index will exceed the critical threshold for human adaptability in the future in the country. The impact of climate change on heat index risk in Iran is significant in the future. To cope with this crucial situation, developing early warning systems and health care strategies to deal with population growth and remarkable socio-economic features in future is essential.

Future heat stress arising from climate change on Iran's population health

NASA Astrophysics Data System (ADS)

Modarres, Reza; Ghadami, Mohammad; Naderi, Sohrab; Naderi, Mohammad

2018-04-01

Climate change-induced extreme heat events are becoming a major issue in different parts of the world, especially in developing countries. The assessment of regional and temporal past and future change in heat waves is a crucial task for public health strategies and managements. The historical and future heat index (HI) time series are investigated for temporal change across Iran to study the impact of global warming on public health. The heat index is calculated, and the nonparametric trend assessment is carried out for historical time series (1981-2010). The future change in heat index is also projected for 2020-2049 and 2070-2099 periods. A rise in the historical heat index and extreme caution conditions for summer and spring seasons for major parts of Iran are notable for historical (1981-2010) series in this study. Using different climate change scenarios shows that heat index will exceed the critical threshold for human adaptability in the future in the country. The impact of climate change on heat index risk in Iran is significant in the future. To cope with this crucial situation, developing early warning systems and health care strategies to deal with population growth and remarkable socio-economic features in future is essential.

A Genome-wide Association Analysis of a Broad Psychosis Phenotype Identifies Three Loci for Further Investigation

PubMed Central

2014-01-01

Background Genome-wide association studies (GWAS) have identified several loci associated with schizophrenia and/or bipolar disorder. We performed a GWAS of psychosis as a broad syndrome rather than within specific diagnostic categories. Methods 1239 cases with schizophrenia, schizoaffective disorder, or psychotic bipolar disorder; 857 of their unaffected relatives, and 2739 healthy controls were genotyped with the Affymetrix 6.0 single nucleotide polymorphism (SNP) array. Analyses of 695,193 SNPs were conducted using UNPHASED, which combines information across families and unrelated individuals. We attempted to replicate signals found in 23 genomic regions using existing data on nonoverlapping samples from the Psychiatric GWAS Consortium and Schizophrenia-GENE-plus cohorts (10,352 schizophrenia patients and 24,474 controls). Results No individual SNP showed compelling evidence for association with psychosis in our data. However, we observed a trend for association with same risk alleles at loci previously associated with schizophrenia (one-sided p = .003). A polygenic score analysis found that the Psychiatric GWAS Consortium’s panel of SNPs associated with schizophrenia significantly predicted disease status in our sample (p = 5 × 10–14) and explained approximately 2% of the phenotypic variance. Conclusions Although narrowly defined phenotypes have their advantages, we believe new loci may also be discovered through meta-analysis across broad phenotypes. The novel statistical methodology we introduced to model effect size heterogeneity between studies should help future GWAS that combine association evidence from related phenotypes. Applying these approaches, we highlight three loci that warrant further investigation. We found that SNPs conveying risk for schizophrenia are also predictive of disease status in our data. PMID:23871474

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.

PubMed

Bramon, Elvira; Pirinen, Matti; Strange, Amy; Lin, Kuang; Freeman, Colin; Bellenguez, Céline; Su, Zhan; Band, Gavin; Pearson, Richard; Vukcevic, Damjan; Langford, Cordelia; Deloukas, Panos; Hunt, Sarah; Gray, Emma; Dronov, Serge; Potter, Simon C; Tashakkori-Ghanbaria, Avazeh; Edkins, Sarah; Bumpstead, Suzannah J; Arranz, Maria J; Bakker, Steven; Bender, Stephan; Bruggeman, Richard; Cahn, Wiepke; Chandler, David; Collier, David A; Crespo-Facorro, Benedicto; Dazzan, Paola; de Haan, Lieuwe; Di Forti, Marta; Dragović, Milan; Giegling, Ina; Hall, Jeremy; Iyegbe, Conrad; Jablensky, Assen; Kahn, René S; Kalaydjieva, Luba; Kravariti, Eugenia; Lawrie, Stephen; Linszen, Don H; Mata, Ignacio; McDonald, Colm; McIntosh, Andrew; Myin-Germeys, Inez; Ophoff, Roel A; Pariante, Carmine M; Paunio, Tiina; Picchioni, Marco; Ripke, Stephan; Rujescu, Dan; Sauer, Heinrich; Shaikh, Madiha; Sussmann, Jessika; Suvisaari, Jaana; Tosato, Sarah; Toulopoulou, Timothea; Van Os, Jim; Walshe, Muriel; Weisbrod, Matthias; Whalley, Heather; Wiersma, Durk; Blackwell, Jenefer M; Brown, Matthew A; Casas, Juan P; Corvin, Aiden; Duncanson, Audrey; Jankowski, Janusz A Z; Markus, Hugh S; Mathew, Christopher G; Palmer, Colin N A; Plomin, Robert; Rautanen, Anna; Sawcer, Stephen J; Trembath, Richard C; Wood, Nicholas W; Barroso, Ines; Peltonen, Leena; Lewis, Cathryn M; Murray, Robin M; Donnelly, Peter; Powell, John; Spencer, Chris C A

2014-03-01

Genome-wide association studies (GWAS) have identified several loci associated with schizophrenia and/or bipolar disorder. We performed a GWAS of psychosis as a broad syndrome rather than within specific diagnostic categories. 1239 cases with schizophrenia, schizoaffective disorder, or psychotic bipolar disorder; 857 of their unaffected relatives, and 2739 healthy controls were genotyped with the Affymetrix 6.0 single nucleotide polymorphism (SNP) array. Analyses of 695,193 SNPs were conducted using UNPHASED, which combines information across families and unrelated individuals. We attempted to replicate signals found in 23 genomic regions using existing data on nonoverlapping samples from the Psychiatric GWAS Consortium and Schizophrenia-GENE-plus cohorts (10,352 schizophrenia patients and 24,474 controls). No individual SNP showed compelling evidence for association with psychosis in our data. However, we observed a trend for association with same risk alleles at loci previously associated with schizophrenia (one-sided p = .003). A polygenic score analysis found that the Psychiatric GWAS Consortium's panel of SNPs associated with schizophrenia significantly predicted disease status in our sample (p = 5 × 10(-14)) and explained approximately 2% of the phenotypic variance. Although narrowly defined phenotypes have their advantages, we believe new loci may also be discovered through meta-analysis across broad phenotypes. The novel statistical methodology we introduced to model effect size heterogeneity between studies should help future GWAS that combine association evidence from related phenotypes. Applying these approaches, we highlight three loci that warrant further investigation. We found that SNPs conveying risk for schizophrenia are also predictive of disease status in our data. Copyright © 2014 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Investigating the Relationships Between Alcohol Consumption, Cannabis Use, and Circulating Cytokines: A Preliminary Analysis.

PubMed

Karoly, Hollis C; Bidwell, L Cinnamon; Mueller, Raeghan L; Hutchison, Kent E

2018-03-01

In recent years, human and animal studies have converged to support altered inflammatory signaling as a molecular mechanism underlying the pathophysiology of alcohol use disorders (AUDs). Alcohol binds to receptors on immune cells, triggering signaling pathways that produce pro-inflammatory cytokines. Chronic inflammation is associated with tissue damage, which may contribute to negative effects of AUD. Conversely, cannabis is associated with decreased inflammatory signaling, and animal studies suggest that cannabinoids may impact alcohol-induced inflammation. Thus, the impact of cannabis on inflammation in AUDs in humans warrants examination. We explored the relationship between self-reported alcohol and cannabis use and circulating levels of the pro-inflammatory cytokines interleukin 6 (IL-6), IL-8, and IL-1β in the blood. Among 66 regular drinkers (mean age = 30.08), we examined circulating cytokines and administered questionnaires assessing alcohol consumption and days of cannabis use over the past 90 days. We examined whether alcohol consumption, cannabis use, and gender were associated with changes in circulating cytokines, and whether there was a significant interaction between alcohol and cannabis use predicting blood levels of circulating cytokines. A positive association between alcohol and IL-6 emerged. We also observed a negative association between cannabis and IL-1β. Follow-up moderation analyses indicated a cannabis by alcohol interaction predicting circulating IL-6, such that cannabis nonusers showed a stronger relationship between alcohol and IL-6 compared to cannabis users. These preliminary findings suggest that cannabinoid compounds may serve to mitigate inflammation associated with alcohol use. In addition, the present results provide data to inform future investigations, with the goal of ultimately leveraging knowledge of the role of inflammation in AUDs to develop more effective treatments focused on novel immune targets. Copyright �

The future of Astrometry in Space

NASA Astrophysics Data System (ADS)

Vallenari, Antonella

2018-04-01

This contribution focuses on the importance of astrometry and on its future developments. Over the centuries astrometry has greatly contributed to the advance of the knowledge of the Universe. Nowadays a major breakthrough is on the way due to astrometric sky surveys from space. ESA space missions Hipparcos first and then Gaia point out the outstanding contribution that space astrometry can provide to our knowledge in many fields of astrophysics, going from the Milky Way formation and evolution, to stellar astrophysics, extra-galactic astrophysics, and fundamental physics. We briefly outline the properties of Gaia first and second data release, and the accuracies expected end-of-mission. The next big advance in space astrometry would be either to improve the astrometric accuracy of one order of magnitude, or to move to a different wavelength domain. While both options have the potential to bring us in a new era of discovery, they have to face enormous issues. We summarize the future directions in space astrometry that are proposed or under investigation by the scientific community, their main challenges and the expected outcome.

NASA Future Forum

NASA Image and Video Library

2012-02-21

The Ohio State University President E. Gordon Gee speaks during the NASA Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

NASA Public Affairs Officer Lauren Worley kicks off the second day of the NASA Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

Medial Temporal Lobe Contributions to Episodic Future Thinking: Scene Construction or Future Projection?

PubMed

Palombo, D J; Hayes, S M; Peterson, K M; Keane, M M; Verfaellie, M

2018-02-01

Previous research has shown that the medial temporal lobes (MTL) are more strongly engaged when individuals think about the future than about the present, leading to the suggestion that future projection drives MTL engagement. However, future thinking tasks often involve scene processing, leaving open the alternative possibility that scene-construction demands, rather than future projection, are responsible for the MTL differences observed in prior work. This study explores this alternative account. Using functional magnetic resonance imaging, we directly contrasted MTL activity in 1) high scene-construction and low scene-construction imagination conditions matched in future thinking demands and 2) future-oriented and present-oriented imagination conditions matched in scene-construction demands. Consistent with the alternative account, the MTL was more active for the high versus low scene-construction condition. By contrast, MTL differences were not observed when comparing the future versus present conditions. Moreover, the magnitude of MTL activation was associated with the extent to which participants imagined a scene but was not associated with the extent to which participants thought about the future. These findings help disambiguate which component processes of imagination specifically involve the MTL. Published by Oxford University Press 2016.

HIV Treatment Produces Economic Returns Through Increased Work And Education, And Warrants Continued US Support

PubMed Central

Thirumurthy, Harsha; Galárraga, Omar; Larson, Bruce; Rosen, Sydney

2013-01-01

Federal expenditures are under scrutiny in the United States, and the merits of continuing and expanding the President’s Emergency Plan for AIDS Relief (PEPFAR) to support access to antiretroviral therapy have become a topic of debate. A growing body of research on the economic benefits of treatment with antiretroviral therapy has important implications for these discussions. For example, research conducted since the inception of PEPFAR shows that HIV-infected adults who receive antiretroviral therapy often begin or resume productive work, and that children living in households with infected adults who are on treatment are more likely to attend school than those in households with untreated adults. These benefits should be considered when weighing the overall benefits of providing antiretroviral therapy against its costs, particularly in the context of discussions about the future of PEPFAR. A modest case can also be made in favor of having private companies in HIV-affected countries provide antiretroviral therapy to their employees and dependents, thus sharing some of the burden of funding HIV treatment. PMID:22778336

[Research in space environmental medicine: review and future].

PubMed

Yu, Xue-jun; Qi, Zhang-nian; Chang, Shao-yong; Liang, Hong; Liu, Hong-tao

2003-01-01

The investigation progress of space environmental medicine in China is summarized. Then, the application of space environmental medicine to formulating medical requirements for the crew module design, and performing medical evaluation for Shenzhou spaceship are addressed. Additionally, the medical and engineering means for the protection from harmful agents during spaceflight is illustrated. Finally, the objective and challenge of space environment medicine faced in the future research in China are presented.

Will urban expansion lead to an increase in future water pollution loads?--a preliminary investigation of the Haihe River Basin in northeastern China.

PubMed

Dong, Yang; Liu, Yi; Chen, Jining

2014-01-01

Urban expansion is a major driving force changing regional hydrology and nonpoint source pollution. The Haihe River Basin, the political, economic, and cultural center of northeastern China, has undergone rapid urbanization in recent decades. To investigate the consequences of future urban sprawl on nonpoint source water pollutant emissions in the river basin, the urban sprawl in 2030 was estimated, and the annual runoff and nonpoint source pollution in the Haihe River basin were simulated. The Integrated Model of Non-Point Sources Pollution Processes (IMPULSE) was used to simulate the effects of urban sprawl on nonpoint source pollution emissions. The outcomes indicated that the urban expansion through 2030 increased the nonpoint source total nitrogen (TN), total phosphorous (TP), and chemical oxygen demand (COD) emissions by 8.08, 0.14, and 149.57 kg/km(2), respectively. Compared to 2008, the total nonpoint emissions rose by 15.33, 0.57, and 12.39 %, respectively. Twelve percent of the 25 cities in the basin would increase by more than 50 % in nonpoint source TN and COD emissions in 2030. In particular, the nonpoint source TN emissions in Xinxiang, Jiaozuo, and Puyang would rise by 73.31, 67.25, and 58.61 %, and the nonpoint source COD emissions in these cities would rise by 74.02, 51.99, and 53.27 %, respectively. The point source pollution emissions in 2008 and 2030 were also estimated to explore the effects of urban sprawl on total water pollution loads. Urban sprawl through 2030 would bring significant structural changes of total TN, TP, and COD emissions for each city in the area. The results of this study could provide insights into the effects of urbanization in the study area and the methods could help to recognize the role that future urban sprawl plays in the total water pollution loads in the water quality management process.

The Future of the Office of the Future.

DTIC Science & Technology

1980-01-01

OFFICE HOWARD L. MORCAN d -%1-@32 p THE FUTURE OF THE OFFICE OF THE FUTURE Howard L. Morgan 80-01-02 - i : Department of Decision Sciences The Wharton...School University of Pennsylvania Philadelphia, PA 19104 This paper will be presented at the Office Automation Conference to be held March 3-5, 1980...in Atlanta, Georgia. Research supported in part by the Office of Naval Research under Contract N00014-75-C-0462. 80 3 13 00 ., , !1 COjNzTY CL

Treatment of Thrombotic Antiphospholipid Syndrome: The Rationale of Current Management—An Insight into Future Approaches

PubMed Central

Ubiali, Tania; Meroni, Pier Luigi

2015-01-01

Vascular thrombosis and pregnancy morbidity represent the clinical manifestations of antiphospholipid syndrome (APS), which is serologically characterized by the persistent positivity of antiphospholipid antibodies (aPL). Antiplatelet and anticoagulant agents currently provide the mainstay of APS treatment. However, the debate is still open: controversies involve the intensity and the duration of anticoagulation and the treatment of stroke and refractory cases. Unfortunately, the literature cannot provide definite answers to these controversial issues as it is flawed by many limitations, mainly due to the recruitment of patients not fulfilling laboratory and clinical criteria for APS. The recommended therapeutic management of different aPL-related clinical manifestations is hereby presented, with a critical appraisal of the evidence supporting such approaches. Cutting edge therapeutic strategies are also discussed, presenting the pioneer reports about the efficacy of novel pharmacological agents in APS. Thanks to a better understanding of aPL pathogenic mechanisms, new therapeutic targets will soon be explored. Much work is still to be done to unravel the most controversial issues about APS management: future studies are warranted to define the optimal management according to aPL risk profile and to assess the impact of a strict control of cardiovascular risk factors on disease control. PMID:26075289

Our Future Donors

ERIC Educational Resources Information Center

Miller, Richard E.

2004-01-01

The rhetorical advantages and dangers involved in casting the students as "future donors" are explained. The way in which the institutions have to change for casting its students as future donors is described.

Impact of future fuel properties on aircraft engines and fuel systems

NASA Technical Reports Server (NTRS)

Rudey, R. A.; Grobman, J. S.

1978-01-01

This paper describes and discusses the propulsion-system problems that will most likely be encountered if the specifications of hydrocarbon-based jet fuels must undergo significant changes in the future and, correspondingly, the advances in technology that will be required to minimize the adverse impact of these problems. Several investigations conducted are summarized. Illustrations are used to describe the relative effects of selected fuel properties on the behavior of propulsion-system components and fuel systems. The selected fuel properties are those that are most likely to be relaxed in future fuel specifications. Illustrations are also used to describe technological advances that may be needed in the future. Finally, the technological areas needing the most attention are described, and programs that are under way to address these needs are briefly discussed.

Investigation of Future Thermal Comforts in a Tropical Megacity Using Coupling of Energy Balance Model and Large Eddy Simulation

NASA Astrophysics Data System (ADS)

Sueishi, T.; Yucel, M.; Ashie, Y.; Varquez, A. C. G.; Inagaki, A.; Darmanto, N. S.; Nakayoshi, M.; Kanda, M.

2017-12-01

Recently, temperature in urban areas continue to rise as an effect of climate change and urbanization. Specifically, Asian megacities are projected to expand rapidly resulting to serious in the future atmospheric environment. Thus, detailed analysis of urban meteorology for Asian megacities is needed to prescribe optimum against these negative climate modifications. A building-resolving large eddy simulation (LES) coupled with an energy balance model is conducted for a highly urbanized district in central Jakarta on typical daytime hours. Five cases were considered; case 1 utilizes present urban scenario and four cases representing different urban configurations in 2050. The future configurations were based on representative concentration pathways (RCP) and shared socio-economic pathways (SSP). Building height maps and land use maps of simulation domains are shown in the attached figure (top). Case 1 3 focuses on the difference of future scenarios. Case 1 represents current climatic and urban conditions, case 2 and 3 was an idealized future represented by RCP2.6/SSP1 and RCP8.5/SSP3, respectively. More complex urban morphology was applied in case 4, vegetation and building area were changed in case 5. Meteorological inputs and anthropogenic heat emission (AHE) were calculated using Weather Research and Forecasting (WRF) model (Varquez et al [2017]). Sensible and latent heat flux from surfaces were calculated using an energy balance model (Ashie et al [2011]), with considers multi-reflection, evapotranspiration and evaporation. The results of energy balance model (shown in the middle line of figure), in addition to WRF outputs, were used as input into the PArallelized LES Model (PALM) (Raasch et al [2001]). From standard new effective temperature (SET*) which included the effects of temperature, wind speed, humidity and radiation, thermal comfort in urban area was evaluated. SET* contours at 1 m height are shown in the bottom line of the figure. Extreme climate

Redefining Employability: Student Voices Mapping Their Dance Journeys and Futures

ERIC Educational Resources Information Center

Higdon, Rachel Delta; Stevens, Jayne

2017-01-01

This paper explores dance students' understanding of employability and their views about their dance futures in order to inform higher education curricula and workforce development. The investigation focuses on the student experience on a Bachelor of Arts Honours degree course in Dance at an English university. First and final year undergraduate…

Internet Technology for Future Space Missions

NASA Technical Reports Server (NTRS)

Hennessy, Joseph F. (Technical Monitor); Rash, James; Casasanta, Ralph; Hogie, Keith

2002-01-01

Ongoing work at National Aeronautics and Space Administration Goddard Space Flight Center (NASA/GSFC), seeks to apply standard Internet applications and protocols to meet the technology challenge of future satellite missions. Internet protocols and technologies are under study as a future means to provide seamless dynamic communication among heterogeneous instruments, spacecraft, ground stations, constellations of spacecraft, and science investigators. The primary objective is to design and demonstrate in the laboratory the automated end-to-end transport of files in a simulated dynamic space environment using off-the-shelf, low-cost, commodity-level standard applications and protocols. The demonstrated functions and capabilities will become increasingly significant in the years to come as both earth and space science missions fly more sensors and the present labor-intensive, mission-specific techniques for processing and routing data become prohibitively. This paper describes how an IP-based communication architecture can support all existing operations concepts and how it will enable some new and complex communication and science concepts. The authors identify specific end-to-end data flows from the instruments to the control centers and scientists, and then describe how each data flow can be supported using standard Internet protocols and applications. The scenarios include normal data downlink and command uplink as well as recovery scenarios for both onboard and ground failures. The scenarios are based on an Earth orbiting spacecraft with downlink data rates from 300 Kbps to 4 Mbps. Included examples are based on designs currently being investigated for potential use by the Global Precipitation Measurement (GPM) mission.

Anticancer activity of Carica papaya: a review.

PubMed

Nguyen, Thao T T; Shaw, Paul N; Parat, Marie-Odile; Hewavitharana, Amitha K

2013-01-01

Carica papaya is widely cultivated in tropical and subtropical countries and is used as food as well as traditional medicine to treat a range of diseases. Increasing anecdotal reports of its effects in cancer treatment and prevention, with many successful cases, have warranted that these pharmacological properties be scientifically validated. A bibliographic search was conducted using the key words "papaya", "anticancer", and "antitumor" along with cross-referencing. No clinical or animal cancer studies were identified and only seven in vitro cell-culture-based studies were reported; these indicate that C. papaya extracts may alter the growth of several types of cancer cell lines. However, many studies focused on specific compounds in papaya and reported bioactivity including anticancer effects. This review summarizes the results of extract-based or specific compound-based investigations and emphasizes the aspects that warrant future research to explore the bioactives in C. papaya for their anticancer activities. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Detecting and developing youth athlete potential: different strokes for different folks are warranted.

PubMed

Suppiah, Haresh T; Low, Chee Yong; Chia, Michael

2015-07-01

Sport talent identification and development (TI and TD) in youth continues to attract strong interest among coaches, sport scientists and sport administrators. TI for sport in youth with the anticipation of future elite level sport achievement is both an art and a science, and is strongly influenced by within athlete and extraneous-to-athlete factors (ecosystem of support or the lack of). The returns from investment on current TI and TD models of sport in youth are subpar in that few continue in the sport to achieve podium positions at the elite sport level in adulthood. Why, where and how one succeeds in sport, and what that success means to the athlete and stakeholders are dependent on the culture and context of the country. We advocate harnessing the power of sport to help in youth development, to be holistic in its nurturance, to allow for individual idiosyncratic expressions of the athletes, to provide for talent transfer across sport, and to facilitate key stakeholders to 'join' hands to work for the common interest and understanding for as many youth and adults so as to provide them with opportunities through support and coaching to compete at the different levels of competition in sport. Governments, policy makers and administrators of sport must decide, within their specific circumstances, if TI and TD in sport in youth is serving a meaningful purpose and is a viable return on investment; in short, is it mission possible or is it… a quest for the Holy Grail for a podium finish in elite level sport competition? Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Forecasting and Maximizing Post-Secondary Futures: Dilemmas Over Negative Futures and Their Hidden Costs.

ERIC Educational Resources Information Center

Hoffman, Benjamin B.

Forecasting models for maximizing postsecondary futures and applications of the model are considered. The forecasting of broad human futures has many parallels to human futures in the field of medical prognosis. The concept of "exasperated negative" is used to refer to the suppression of critical information about a negative future with…

A critical review of "Internet addiction" criteria with suggestions for the future.

PubMed

Van Rooij, Antonius J; Prause, Nicole

2014-12-01

In the last 5 years a deluge of articles on the topic of Internet addiction (IA) has proposed many candidate symptoms as evidence of this proposed disease. We critically reviewed the current approach to the measurement and identification of this new excessive behavior syndrome. Three popular models of IA were discussed: Griffith’s components model; Young’s Internet Addiction Test (IAT); and the criteria by Tao et al. (2010). We selected these models because they are widely cited and propose specific criteria for IA disorder. Our approach is not meant to provide an exhaustive review, but to discuss and critique the most salient trends in the field. The models of Internet addiction share some criteria, including feeling a loss of control over Internet use; ensuing psychological, social, or professional conflict or problems; and preoccupation when not using the Internet. Other criteria inconsistently mentioned include: mood management, tolerance, withdrawal, and craving/anticipation. The models studied here share the assumption that the Internet can produce a qualitative shift to a diseased state in humans. We critically discussed the above criteria and concluded that the evidence base is currently not strong enough to provide support for an Internet addiction disorder. Future research areas are suggested: (1) Focusing on common impaired dimensions, (2) exploring neuroimaging as a model building tool, and (3) identifying shifts in the rewarding aspects of Internet use. Given the lack of consensus on the subject of Internet addiction, a focus on problem behaviors appears warranted.

An Investigation of a Cluster of Parapoxvirus Cases in Missouri, Feb–May 2006: Epidemiologic, Clinical and Molecular Aspects

PubMed Central

Lederman, Edith R.; Tao, Min; Reynolds, Mary G.; Li, Yu; Zhao, Hui; Smith, Scott K.; Sitler, Lisa; Haberling, Dana L.; Davidson, Whitni; Hutson, Christina; Emerson, Ginny; Schnurr, David; Regnery, Russell; Zhu, Bao-Ping; Pue, Howard; Damon, Inger K.

2013-01-01

Simple Summary In the spring of 2006, four human cases of parapoxvirus infections in Missouri residents were reported to the Centers for Disease Control and Prevention (CDC). We conducted surveys of herders and veterinarians, performed animal and environmental sampling and obtained sera from potential case-patients. We determined that, in general, infected persons may seek advice from veterinarians rather than physicians, thereby giving physicians less clinical experience. The initial perception of increased incidence in Missouri was likely due to reporting bias due to misdiagnosis and increased awareness due to recent publications. Basic personal protective measures are not being routinely utilized. Asymptomatic parapoxvirus infections in livestock may be common and warrants further investigation. Abstract In the spring of 2006, four human cases of parapoxvirus infections in Missouri residents were reported to the Centers for Disease Control and Prevention (CDC), two of which were initially diagnosed as cutaneous anthrax. This investigation was conducted to determine the level of recognition of zoonotic parapoxvirus infections and prevention measures, the degree to which veterinarians may be consulted on human infections and what forces were behind this perceived increase in reported infections. Interviews were conducted and clinical and environmental sampling was performed. Swab and scab specimens were analyzed by real-time polymerase chain reaction (PCR), whereas serum specimens were evaluated for parapoxvirus antibodies. Three case patients were found to have fed ill juvenile animals without using gloves. Forty-six percent of veterinarians reported having been consulted regarding suspected human orf infections. Orf virus DNA was detected from five of 25 asymptomatic sheep. Analysis of extracellular envelope gene sequences indicated that sheep and goat isolates clustered in a species-preferential fashion. Parapoxvirus infections are common in Missouri ruminants

Personal Traits and Their Relationship with Future Anxiety and Achievement

ERIC Educational Resources Information Center

Al Qaisy, Lama M.; Thawabieh, Ahmad M.

2017-01-01

This study aimed to investigate the type of personalities that students had and the relationship between personality type with future anxiety and students' achievement. The sample of the study consisted of 304 students from Tafila Technical University and Al-Hussien Bin Talal University. The researchers used the big five scale which was developed…

NASA Future Forum

NASA Image and Video Library

2012-02-21

Laurie Leshin, dean of the School of Science, Rensselaer Polytechnic Institute, left, Mason Peck, NASA Chief Technologist, 2nd from left, Ron Sega, Vice president and enterprise executive for Energy and the Environment, The Ohio State University and Colorado State University, Michael Donovan, technology consultant, New Services Development, Hewlett-Packard Company, and, Jordan Hansell, chairman and CEO, NetJets Inc., right, participate in the NASA Future Forum panel titled "Importance of Technology, Science and Innovation for our Economic Future" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Roger Launius, senior curator, Smithsonian Institution National Air and Space Museum, talks during the NASA Future Forum panel titled "Shifting Roles for Public, Private, and International Players in Space" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Bobby Braun, professor, Georgia Institute of Technology, talks during the NASA Future Forum panel titled "Shifting Roles for Public, Private, and International Players in Space" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Carlos Grodsinsky, Vice Presiden of Technology, Zin Technologies, talks during the NASA Future Forum panel titled "Transferring and Commercializing Technology to Benefit Our Lives and Our Economy" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Neal Seater, President, Greenfield Solar, holds up a small solar chip during the NASA Future Forum panel titled "Transferring and Commercializing Technology to Benefit Our Lives and Our Economy" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Fayette Collier, Aeronautics Research Mission Directorate, NASA Headquarters talks during the NASA Future Forum panel titled "Transferring and Commercializing Technology to Benefit Our Lives and Our Economy" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

Yael Vodovotz, Associate Professor, Department of Food Science and Technology, Ohio State University, talks during the NASA Future Forum panel titled "Transferring and Commercializing Technology to Benefit Our Lives and Our Economy" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

NASA Future Forum

NASA Image and Video Library

2012-02-21

NASA Technology Transfer Program Executive Daniel Lockney moderates the NASA Future Forum panel titled "Transferring and Commercializing Technology to Benefit Our Lives and Our Economy" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

Consumer Feedback to Steer the Future of Assistive Technology Research and Development: A Pilot Study

PubMed Central

Kelleher, Annmarie; Dicianno, Brad E.; Eckstein, Stacy; Schein, Richard; Pearlman, Jonathan

2017-01-01

Objective: The overall objective of this project was to identify consumers' opinions of their needs and wants related to assistive technology (AT) in a systematic and quantitative manner via a questionnaire that can be used to validate existing and establish new research priorities. Methods: This pilot study describes questionnaire development, online implementation, and revisions considered to the questionnaire in preparation for conducting a nationwide survey. Data from a sample (N = 112) are presented. The pilot study was critical to refine the questions and ensure that meaningful information was being collected. Results: It was identified that revisions were warranted to provide more structure and allow for consumers to prioritize AT research efforts. Conclusion: The questionnaire results, although positively in favor of many of the technologies presented, are inconclusive to identify generalizable research priorities, thus expansion to a nationwide population is warranted. PMID:29339885

Systematic arthroscopic investigation of the bovine stifle joint.

PubMed

Hagag, U; Tawfiek, M G; Brehm, W

2015-12-01

The objective of the present study was to establish a protocol for arthroscopic exploration of the bovine stifle joint using craniomedial, caudolateral and caudomedial approaches. An anatomic and arthroscopic study using 26 cadaveric limbs from 13 non-lame adult dairy cows was performed. The craniomedial approach was created between the middle and medial patellar ligaments to investigate the cranial pouches of the stifle joint. The inter-condylar eminence, the proximal aspect of the medial femoral trochlear ridge and the lateral aspect of the lateral femoral condyle were used as starting points for systematic examination of the medial femorotibial, the femoropatellar and the lateral femorotibial joints, respectively. The observed structures were: the suprapatellar pouch, articular surfaces of the patella, femoral trochlear ridges, cruciate ligaments, menisci, and the meniscotibial ligaments. The arthroscopic portal for the caudomedial femorotibial pouch was about 6-8 cm caudal to the medial collateral ligament. The proximal and distal caudolateral femorotibial pouches were explored 3 cm and 1.5 cm caudal to the ipsilateral collateral ligament, respectively. The observed structures were the caudal aspect of femoral condyles, menisci, caudal cruciate ligament, popliteal tendon and the meniscofemoral ligament. Restricted joint size and risk of common peroneal nerve damage were the major limitations for exploration of the caudal femorotibial compartments. The study described the arthroscopic portals and normal intra-articular anatomy of the bovine stifle joint but further investigations are warranted to validate these techniques in clinical cases. Copyright © 2015 Elsevier Ltd. All rights reserved.

Impacts of climate change on the future of biodiversity.

PubMed

Bellard, Céline; Bertelsmeier, Cleo; Leadley, Paul; Thuiller, Wilfried; Courchamp, Franck

2012-04-01

Many studies in recent years have investigated the effects of climate change on the future of biodiversity. In this review, we first examine the different possible effects of climate change that can operate at individual, population, species, community, ecosystem and biome scales, notably showing that species can respond to climate change challenges by shifting their climatic niche along three non-exclusive axes: time (e.g. phenology), space (e.g. range) and self (e.g. physiology). Then, we present the principal specificities and caveats of the most common approaches used to estimate future biodiversity at global and sub-continental scales and we synthesise their results. Finally, we highlight several challenges for future research both in theoretical and applied realms. Overall, our review shows that current estimates are very variable, depending on the method, taxonomic group, biodiversity loss metrics, spatial scales and time periods considered. Yet, the majority of models indicate alarming consequences for biodiversity, with the worst-case scenarios leading to extinction rates that would qualify as the sixth mass extinction in the history of the earth. © 2012 Blackwell Publishing Ltd/CNRS.

Impacts of climate change on the future of biodiversity

PubMed Central

Leadley, Paul; Thuiller, Wilfried; Courchamp, Franck

2013-01-01

Many studies in recent years have investigated the effects of climate change on the future of biodiversity. In this review, we first examine the different possible effects of climate change that can operate at individual, population, species, community, ecosystem and biome scales, notably showing that species can respond to climate change challenges by shifting their climatic niche along three non-exclusive axes: time (e.g., phenology), space (e.g., range) and self (e.g., physiology). Then, we present the principal specificities and caveats of the most common approaches used to estimate future biodiversity at global and sub-continental scales and we synthesize their results. Finally, we highlight several challenges for future research both in theoretical and applied realms. Overall, our review shows that current estimates are very variable, depending on the method, taxonomic group, biodiversity loss metrics, spatial scales and time periods considered. Yet, the majority of models indicate alarming consequences for biodiversity, with the worst-case scenarios leading to extinction rates that would qualify as the sixth mass extinction in the history of the earth. PMID:22257223

Intensified ENSO-Driven Precipitation Teleconnections in the Future

NASA Astrophysics Data System (ADS)

Bonfils, C.; Santer, B. D.; Phillips, T. J.; Marvel, K.; Leung, L. R.; Doutriaux, C.

2014-12-01

The El Niño-Southern Oscillation (ENSO) is an important driver of regional hydroclimate variability through far-reaching teleconnections. Most climate models project an increase in the frequency of extreme El Niño events under increased greenhouse-gas (GHG) forcing. However, it is unclear how other aspects of ENSO and ENSO-driven teleconnections will evolve in the future. Here, we identify in 20th century sea-surface temperature (SST) observations a time-invariant ENSO-like (ENSOL) pattern that is largely uncontaminated by GHG forcing. We use this pattern to investigate the future precipitation (P) response to ENSO-like SST anomalies. Models that better capture observed ENSOL characteristics produce P teleconnection patterns that are in better accord with observations and more stationary in the 21st century. We decompose the future P response to ENSOL into the sum of three terms: (1) the change in P mean state, (2) the historical P response to ENSOL, and (3) a future enhancement in the P response to ENSOL. In many regions, this last term can aggravate the P extremes associated with ENSO variability. This simple decomposition allows us to identify regions likely to experience ENSOL-induced P changes that are without precedent in the current climate. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

Intrapersonal positive future thinking predicts repeat suicide attempts in hospital-treated suicide attempters.

PubMed

O'Connor, Rory C; Smyth, Roger; Williams, J Mark G

2015-02-01

Although there is clear evidence that low levels of positive future thinking (anticipation of positive experiences in the future) and hopelessness are associated with suicide risk, the relationship between the content of positive future thinking and suicidal behavior has yet to be investigated. This is the first study to determine whether the positive future thinking-suicide attempt relationship varies as a function of the content of the thoughts and whether positive future thinking predicts suicide attempts over time. A total of 388 patients hospitalized following a suicide attempt completed a range of clinical and psychological measures (depression, hopelessness, suicidal ideation, suicidal intent and positive future thinking). Fifteen months later, a nationally linked database was used to determine who had been hospitalized again after a suicide attempt. During follow-up, 25.6% of linked participants were readmitted to hospital following a suicide attempt. In univariate logistic regression analyses, previous suicide attempts, suicidal ideation, hopelessness, and depression-as well as low levels of achievement, low levels of financial positive future thoughts, and high levels of intrapersonal (thoughts about the individual and no one else) positive future thoughts predicted repeat suicide attempts. However, only previous suicide attempts, suicidal ideation, and high levels of intrapersonal positive future thinking were significant predictors in multivariate analyses. Positive future thinking has predictive utility over time; however, the content of the thinking affects the direction and strength of the positive future thinking-suicidal behavior relationship. Future research is required to understand the mechanisms that link high levels of intrapersonal positive future thinking to suicide risk and how intrapersonal thinking should be targeted in treatment interventions. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

Intrapersonal Positive Future Thinking Predicts Repeat Suicide Attempts in Hospital-Treated Suicide Attempters

PubMed Central

2014-01-01

Objective: Although there is clear evidence that low levels of positive future thinking (anticipation of positive experiences in the future) and hopelessness are associated with suicide risk, the relationship between the content of positive future thinking and suicidal behavior has yet to be investigated. This is the first study to determine whether the positive future thinking–suicide attempt relationship varies as a function of the content of the thoughts and whether positive future thinking predicts suicide attempts over time. Method: A total of 388 patients hospitalized following a suicide attempt completed a range of clinical and psychological measures (depression, hopelessness, suicidal ideation, suicidal intent and positive future thinking). Fifteen months later, a nationally linked database was used to determine who had been hospitalized again after a suicide attempt. Results: During follow-up, 25.6% of linked participants were readmitted to hospital following a suicide attempt. In univariate logistic regression analyses, previous suicide attempts, suicidal ideation, hopelessness, and depression—as well as low levels of achievement, low levels of financial positive future thoughts, and high levels of intrapersonal (thoughts about the individual and no one else) positive future thoughts predicted repeat suicide attempts. However, only previous suicide attempts, suicidal ideation, and high levels of intrapersonal positive future thinking were significant predictors in multivariate analyses. Discussion: Positive future thinking has predictive utility over time; however, the content of the thinking affects the direction and strength of the positive future thinking–suicidal behavior relationship. Future research is required to understand the mechanisms that link high levels of intrapersonal positive future thinking to suicide risk and how intrapersonal thinking should be targeted in treatment interventions. PMID:25181026

Current and future use of point-of-care tests in primary care: an international survey in Australia, Belgium, The Netherlands, the UK and the USA

PubMed Central

Howick, Jeremy; Cals, Jochen W L; Jones, Caroline; Price, Christopher P; Plüddemann, Annette; Heneghan, Carl; Berger, Marjolein Y; Buntinx, Frank; Hickner, John; Pace, Wilson; Badrick, Tony; Van den Bruel, Ann; Laurence, Caroline; van Weert, Henk C; van Severen, Evie; Parrella, Adriana; Thompson, Matthew

2014-01-01

Objective Despite the growing number of point-of-care (POC) tests available, little research has assessed primary care clinician need for such tests. We therefore aimed to determine which POC tests they actually use or would like to use (if not currently available in their practice). Design Cross-sectional survey. Setting Primary care in Australia, Belgium (Flanders region only), the Netherlands, the UK and the USA. Participants Primary care doctors (general practitioners, family physicians). Main measures We asked respondents to (1) identify conditions for which a POC test could help inform diagnosis, (2) from a list of tests provided: evaluate which POC tests they currently use (and how frequently) and (3) determine which tests (from that same list) they would like to use in the future (and how frequently). Results 2770 primary care clinicians across five countries responded. Respondents in all countries wanted POC tests to help them diagnose acute conditions (infections, acute cardiac disease, pulmonary embolism/deep vein thrombosis), and some chronic conditions (diabetes, anaemia). Based on the list of POC tests provided, the most common tests currently used were: urine pregnancy, urine leucocytes or nitrite and blood glucose. The most commonly reported tests respondents expressed a wish to use in the future were: D-dimer, troponin and chlamydia. The UK and the USA reported a higher actual and desired use for POC tests than Australia, Belgium and the Netherlands. Our limited data suggest (but do not confirm) representativeness. Conclusions Primary care clinicians in all five countries expressed a desire for POC tests to help them diagnose a range of acute and chronic conditions. Rates of current reported use and desired future use were generally high for a small selection of POC tests, but varied across countries. Future research is warranted to explore how specific POC tests might improve primary care. PMID:25107438

Women Shaping the Future. The Future of Work Discussion Kit.

ERIC Educational Resources Information Center

Pine, Janet; Jackson, Sue; MacNeill, Kate

Designed to inform and empower women to participate in debates and decisions about the future of work in Australia, this kit provides everything needed to run a discussion session on the future of work with women in the community. It consists of a guide for users, workshop guide, topic sheets, and background reading. The guide for users introduces…

NASA Future Forum

NASA Image and Video Library

2012-02-21

John Logsdon, professor emeritus of Political Science and International Affairs, Elliott School of International Affairs, George Washington University, talks during the NASA Future Forum panel titled "Shifting Roles for Public, Private, and International Players in Space" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

Investigating links between shale gas development and health impacts through a community survey project in Pennsylvania.

PubMed

Steinzor, Nadia; Subra, Wilma; Sumi, Lisa

2013-01-01

Across the United States, the race for new energy sources is picking up speed and reaching more places, with natural gas in the lead. While the toxic and polluting qualities of substances used and produced in shale gas development and the general health effects of exposure are well established, scientific evidence of causal links has been limited, creating an urgent need to understand health impacts. Self-reported survey research documenting the symptoms experienced by people living in proximity to gas facilities, coupled with environmental testing, can elucidate plausible links that warrant both response and further investigation. This method, recently applied to the gas development areas of Pennsylvania, indicates the need for a range of policy and research efforts to safeguard public health.

Future impacts of global warming and reforestation on drought patterns over West Africa

NASA Astrophysics Data System (ADS)

Diasso, Ulrich; Abiodun, Babatunde J.

2017-07-01

This study investigates how a large-scale reforestation in Savanna (8-12°N, 20°W-20°E) could affect drought patterns over West Africa in the future (2031-2060) under the RCP4.5 scenario. Simulations from two regional climate models (RegCM4 and WRF) were analyzed for the study. The study first evaluated the performance of both RCMs in simulating the present-day climate and then applied the models to investigate the future impacts of global warming and reforestation on the drought patterns. The simulated and observed droughts were characterized with the Standardized Precipitation and Evapotranspiration Index (SPEI), and the drought patterns were classified using a Self-organizing Map (SOM) technique. The models capture essential features in the seasonal rainfall and temperature fields (including the Saharan Heat Low), but struggle to reproduce the onset and retreat of the West African Monsoon as observed. Both RCMs project a warmer climate (about 1-2 °C) over West Africa in the future. They do not reach a consensus on future change in rainfall, but they agree on a future increase in frequency of severe droughts (by about 2 to 9 events per decade) over the region. They show that reforestation over the Savanna could reduce the future warming by 0.1 to 0.8 °C and increase the precipitation by 0.8 to 1.2 mm per day. However, the impact of reforestation on the frequency of severe droughts is twofold. While reforestation decreases the droughts frequency (by about 1-2 events per decade) over the Savanna and Guinea coast, it increases droughts frequency (by 1 event per decade) over the Sahel, especially in July to September. The results of this study have application in using reforestation to mitigate impacts of climate change in West Africa.

Parenting and Adolescents' Depressive Symptoms: The Mediating Role of Future Time Perspective.

PubMed

Diaconu-Gherasim, Loredana R; Bucci, Colleen M; Giuseppone, Kathryn R; Brumariu, Laura E

2017-10-03

This study investigated the relations between maternal and paternal rearing practices and adolescents' depressive symptoms, and whether time perspective in adolescence explains these links. The sample included 306 students (158 girls), aged between 10.83 and 14.42 years. Adolescents completed questionnaires assessing their perceptions of maternal and paternal acceptance and psychological control, and of their future time perspective and depressive symptoms. Adolescents who rated their mothers as more accepting and those who rated their fathers as less psychologically controlling also reported lower levels of depressive symptoms and greater future time perspective. Further, adolescents who had greater future time perspective reported lower levels of depressive symptoms. Finally, time perspective partially mediated the relations of maternal and paternal acceptance, and paternal control with depressive symptoms in adolescence. The findings highlight the unique relations of maternal acceptance and paternal psychological control with adolescents' depressive symptoms, and that future time perspective is one mechanism that might explain why parenting strategies are linked with depressive symptoms in adolescence.

77 FR 53893 - Privacy Act of 1974; Department of Homeland Security U.S. Immigration and Customs Enforcement-005...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

... to identify statistically anomalous transactions that may warrant investigation for money laundering... identify anomalies in patterns of trade. Such anomalies can indicate trade-based money laundering or other... transactions that may warrant investigation for money laundering or other import-export crimes. DARTTS is...

INVESTIGATIONS IN PANAMA DURING THE SUMMER OF 1930.

PubMed

Faust, E C

1931-01-09

The material obtained from these investigations has indicated to the writer that the area studied offers extremely valuable opportunities for helminthological and protozoological work. The data obtained will serve as the basis for several important papers which will be published in the near future.

Large-scale academic achievement testing of deaf and hard-of-hearing students: past, present, and future.

PubMed

Qi, Sen; Mitchell, Ross E

2012-01-01

The first large-scale, nationwide academic achievement testing program using Stanford Achievement Test (Stanford) for deaf and hard-of-hearing children in the United States started in 1969. Over the past three decades, the Stanford has served as a benchmark in the field of deaf education for assessing student academic achievement. However, the validity and reliability of using the Stanford for this special student population still require extensive scrutiny. Recent shifts in educational policy environment, which require that schools enable all children to achieve proficiency through accountability testing, warrants a close examination of the adequacy and relevance of the current large-scale testing of deaf and hard-of-hearing students. This study has three objectives: (a) it will summarize the historical data over the last three decades to indicate trends in academic achievement for this special population, (b) it will analyze the current federal laws and regulations related to educational testing and special education, thereby identifying gaps between policy and practice in the field, especially identifying the limitations of current testing programs in assessing what deaf and hard-of-hearing students know, and (c) it will offer some insights and suggestions for future testing programs for deaf and hard-of-hearing students.

Future Flight Decks

NASA Technical Reports Server (NTRS)

Arbuckle, P. Douglas; Abbott, Kathy H.; Abbott, Terence S.; Schutte, Paul C.

1998-01-01

The evolution of commercial transport flight deck configurations over the past 20-30 years and expected future developments are described. Key factors in the aviation environment are identified that the authors expect will significantly affect flight deck designers. One of these is the requirement for commercial aviation accident rate reduction, which is probably required if global commercial aviation is to grow as projected. Other factors include the growing incrementalism in flight deck implementation, definition of future airspace operations, and expectations of a future pilot corps that will have grown up with computers. Future flight deck developments are extrapolated from observable factors in the aviation environment, recent research results in the area of pilot-centered flight deck systems, and by considering expected advances in technology that are being driven by other than aviation requirements. The authors hypothesize that revolutionary flight deck configuration changes will be possible with development of human-centered flight deck design methodologies that take full advantage of commercial and/or entertainment-driven technologies.

Future Orientation, Impulsivity, and Problem Behaviors: A Longitudinal Moderation Model

ERIC Educational Resources Information Center

Chen, Pan; Vazsonyi, Alexander T.

2011-01-01

In the current study, based on a sample of 1,873 adolescents between 11.4 and 20.9 years of age from the first 3 waves of the National Longitudinal Study of Adolescent Health, we investigated the longitudinal effects of future orientation on levels of and developmental changes in problem behaviors, while controlling for the effects by impulsivity;…

Young People's Life-Skills and the Future. Research Report Series.

ERIC Educational Resources Information Center

Powney, Janet; Lowden, Kevin; Hall, Stuart

A study investigated what Scottish and English young people consider important life skills, how they believe they develop them, and how necessary they see them to their future lives. More than 200 16-21-year-olds examined photographs of events related to basic life tasks, family, close relationships, work or school and leisure activities and then…

Elementary School Students' Perceptions of the Future Environment through Artwork

ERIC Educational Resources Information Center

Özsoy, Sibel; Ahi, Berat

2014-01-01

The purpose of the present study is to investigate first level of elementary school students' perceptions of the future state of the environment through the pictures they draw. The participants of the study are 131 first-grade students, 127 second-grade students, 160 third-grade students, 188 fourth-grade students, and 222 fifth-grade students,…

In vivo targeting and imaging of tumor vasculature with radiolabeled, antibody-conjugated nanographene.

PubMed

Hong, Hao; Yang, Kai; Zhang, Yin; Engle, Jonathan W; Feng, Liangzhu; Yang, Yunan; Nayak, Tapas R; Goel, Shreya; Bean, Jero; Theuer, Charles P; Barnhart, Todd E; Liu, Zhuang; Cai, Weibo

2012-03-27

Herein we demonstrate that nanographene can be specifically directed to the tumor neovasculature in vivo through targeting of CD105 (i.e., endoglin), a vascular marker for tumor angiogenesis. The covalently functionalized nanographene oxide (GO) exhibited excellent stability and target specificity. Pharmacokinetics and tumor targeting efficacy of the GO conjugates were investigated with serial noninvasive positron emission tomography imaging and biodistribution studies, which were validated by in vitro, in vivo, and ex vivo experiments. The incorporation of an active targeting ligand (TRC105, a monoclonal antibody that binds to CD105) led to significantly improved tumor uptake of functionalized GO, which was specific for the neovasculature with little extravasation, warranting future investigation of these GO conjugates for cancer-targeted drug delivery and/or photothermal therapy to enhance therapeutic efficacy. Since poor extravasation is a major hurdle for nanomaterial-based tumor targeting in vivo, this study also establishes CD105 as a promising vascular target for future cancer nanomedicine. © 2012 American Chemical Society

Power and spectrally efficient M-ARY QAM schemes for future mobile satellite communications

NASA Technical Reports Server (NTRS)

Sreenath, K.; Feher, K.

1990-01-01

An effective method to compensate nonlinear phase distortion caused by the mobile amplifier is proposed. As a first step towards the future use of spectrally efficient modulation schemes for mobile satellite applications, we have investigated effects of nonlinearities and the phase compensation method on 16-QAM. The new method provides about 2 dB savings in power for 16-QAM operation with cost effective amplifiers near saturation and thereby promising use of spectrally efficient linear modulation schemes for future mobile satellite applications.

Warrants for major traffic generator guide signing.

DOT National Transportation Integrated Search

2009-09-01

Major traffic generators (MTGs) are important regional attractions, events, or facilities that attract persons or groups from beyond a local community, city, or metropolitan area. MTGs are significant because of their unique educational, cultural, hi...

Measuring Distribution Performance? Benchmarking Warrants Your Attention

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ericson, Sean J; Alvarez, Paul

Identifying, designing, and measuring performance metrics is critical to securing customer value, but can be a difficult task. This article examines the use of benchmarks based on publicly available performance data to set challenging, yet fair, metrics and targets.

12 CFR 263.94 - Conduct warranting sanctions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... an attorney, or debarment or suspension from practice as a certified public accountant or public... that individual's period of suspension, debarment, or ineligibility; (f) Contemptuous conduct in... circulating or publishing malicious or libelous matter; (g) Suspension or debarment from practice before the...

8 CFR 1241.32 - Warrant of deportation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... case shall be issued by a district director. The district director shall exercise the authority... his or her mental or physical condition requires personal care and attention en route to his or her...

8 CFR 241.2 - Warrant of removal.

Code of Federal Regulations, 2014 CFR

2014-01-01

... administrative removal order in the alien's case shall be issued by any of the following immigration officials... whether his or her mental or physical condition requires personal care and attention en route to his or...

8 CFR 1241.32 - Warrant of deportation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... case shall be issued by a district director. The district director shall exercise the authority... his or her mental or physical condition requires personal care and attention en route to his or her...

8 CFR 241.2 - Warrant of removal.

Code of Federal Regulations, 2013 CFR

2013-01-01

... administrative removal order in the alien's case shall be issued by any of the following immigration officials... whether his or her mental or physical condition requires personal care and attention en route to his or...

8 CFR 1241.32 - Warrant of deportation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... case shall be issued by a district director. The district director shall exercise the authority... his or her mental or physical condition requires personal care and attention en route to his or her...

8 CFR 1241.32 - Warrant of deportation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... case shall be issued by a district director. The district director shall exercise the authority... his or her mental or physical condition requires personal care and attention en route to his or her...

8 CFR 241.2 - Warrant of removal.

Code of Federal Regulations, 2012 CFR

2012-01-01

... administrative removal order in the alien's case shall be issued by any of the following immigration officials... whether his or her mental or physical condition requires personal care and attention en route to his or...

8 CFR 241.2 - Warrant of removal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... administrative removal order in the alien's case shall be issued by any of the following immigration officials... whether his or her mental or physical condition requires personal care and attention en route to his or...

8 CFR 241.2 - Warrant of removal.

Code of Federal Regulations, 2010 CFR

2010-01-01

...: (i) Director, Detention and Removal Operations; (ii) Deputy Assistant Director, Field Operations... Directors; (xxi) Deputy Port Directors; (xxii) Assistant Port Directors; (xxiii) Director, Field Operations; (xxiv) Deputy Director, Field Operations; (xxv) Assistant Director, Field Operations; and (xxvi) Other...

Pension funds warrant a financial manager's review.

PubMed

Seidner, A G

1990-10-01

A hospital's pension funds may be managed by its finance department, another internal department, or an outside investment adviser. Whatever the arrangement, healthcare financial managers should be involved in the decision between internal and external management of pension funds. A financial manager also can play a prominent role in developing a pension fund policy that balances a hospital's commitment to legal requirements, pension plan goals, and communication with investment advisers.

United States Navy Contracting Officer Warranting Process

DTIC Science & Technology

2011-03-01

by 30% or more of the respondents: Contract Law , Cost Analysis, Market Research, Contract Source Selection, Simplified Acquisition Procedures, and...that the majority of AOs found the following course at least somewhat important: Contract Law , Cost Analysis, Market Research, Contract 52 Source...the budget and appropriation cycle 4. Ethics and conduct standards 5. Basic contract laws and regulations 6. Socio-economic requirements in

Total Warrant Officer System (TWOS). Volume 1

DTIC Science & Technology

1985-08-30

Compensation DiGirolamo, Nicholas A. CW4 OD ARNG Representative Dougherty, John R. CW4 AV Action Officer Hawk, Chuck CW4 AV Branch Chief Jinks, Dennis M. CW4...NCOIC Knight, Lewis D. SSG 81E Illustrator Cunningham, Linda L. SGT 71C Secretary/ Steno Grigsby, Steven A. SP4 64C Driver iv - ---- . "%o EXECUTIVE

Bioactive endophytes warrant intensified exploration and conservation.

PubMed

Smith, Stephen A; Tank, David C; Boulanger, Lori-Ann; Bascom-Slack, Carol A; Eisenman, Kaury; Kingery, David; Babbs, Beatrice; Fenn, Kathleen; Greene, Joshua S; Hann, Bradley D; Keehner, Jocelyn; Kelley-Swift, Elizabeth G; Kembaiyan, Vivek; Lee, Sun Jin; Li, Puyao; Light, David Y; Lin, Emily H; Ma, Cong; Moore, Emily; Schorn, Michelle A; Vekhter, Daniel; Nunez, Percy V; Strobel, Gary A; Donoghue, Michael J; Strobel, Scott A

2008-08-25

A key argument in favor of conserving biodiversity is that as yet undiscovered biodiversity will yield products of great use to humans. However, the link between undiscovered biodiversity and useful products is largely conjectural. Here we provide direct evidence from bioassays of endophytes isolated from tropical plants and bioinformatic analyses that novel biology will indeed yield novel chemistry of potential value. We isolated and cultured 135 endophytic fungi and bacteria from plants collected in Peru. nrDNAs were compared to samples deposited in GenBank to ascertain the genetic novelty of cultured specimens. Ten endophytes were found to be as much as 15-30% different than any sequence in GenBank. Phylogenetic trees, using the most similar sequences in GenBank, were constructed for each endophyte to measure phylogenetic distance. Assays were also conducted on each cultured endophyte to record bioactivity, of which 65 were found to be bioactive. The novelty of our contribution is that we have combined bioinformatic analyses that document the diversity found in environmental samples with culturing and bioassays. These results highlight the hidden hyperdiversity of endophytic fungi and the urgent need to explore and conserve hidden microbial diversity. This study also showcases how undergraduate students can obtain data of great scientific significance.

The nuclear pacemaker: Is renewed interest warranted

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parsonnet, V.; Berstein, A.D.; Perry, G.Y.

1990-10-01

From 1973 through 1987, 155 radioisotope-powered nuclear pacemakers were implanted in 132 patients at the Newark Beth Israel Medical Center. The longevity of the first 15 devices, all of which were fixed-rate (VOO) pacemakers, was significantly better than that of 15 lithium-chemistry demand (VVI) pacemakers used as control devices (p = 0.0002). Of the entire cohort of 155 nuclear pacemakers, 136 were VVI devices and 19 were VOO units. The patients with VOO pacemakers needed reoperations more often than did those with VVI pacemakers, chiefly for mode change (p less than 0.001). Power-source failure was observed in only 1 case,more » but 47 nuclear pacemakers were removed for other reasons, including component malfunction (15 units), mode change (12 units), high pacing thresholds (8 units) and lead or connector problems (5 units). The actuarial survival at 15 years was 99% for power sources and 82% for the entire pacing systems (pulse generators plus leads). The frequency of malignancy was similar to that of the population at large and primary tumor sites were randomly distributed. Deaths most commonly were due to cardiac causes (68%). Thus, nuclear pacemakers are safe and reliable and their greater initial cost appears to be offset by their longevity and the resulting decrease in the frequency of reoperations. It is reasonable to suggest that further use be made of long-lasting nuclear power sources for modern pacemakers and other implantable rhythm-management devices.« less

Attributions, future time perspective and career maturity in nursing undergraduates: correlational study design.

PubMed

Cheng, Cheng; Yang, Liu; Chen, Yuxia; Zou, Huijing; Su, Yonggang; Fan, Xiuzhen

2016-01-25

Career maturity is an important parameter as nursing undergraduates prepare for their future careers. However, little is known regarding the relationships between attributions, future time perspective and career maturity among nursing undergraduates. The purpose of this study was to investigate the degree of career maturity and its relationship with attributions and future time perspective. A cross-sectional survey was designed. This survey was administered to 431 Chinese nursing undergraduates. Independent-sample t-tests and one-way ANOVA were performed to examine the mean differences between categories of binary and categorical demographic characteristics, respectively. Pearson correlations and multiple linear regressions were used to test the relationships between attributions, future time perspective and career maturity. The degree of career maturity was moderate among nursing undergraduates and that internal attributions of academic achievement, future efficacy and future purpose consciousness were positively associated with career maturity (all p < 0.01). These three factors accounted for 37.6% of the variance in career maturity (adjusted R(2) = 0.376). These findings might assist nursing educators and career counselors to improve nursing undergraduate career maturity by elucidating the imperative roles of internal attributions and future time perspective and to facilitate their transition from school to clinical practice.

Protecting Future Biodiversity via Re-allocation of Future Land-use Change Patterns

NASA Astrophysics Data System (ADS)

Chini, L. P.; Hurtt, G. C.; Jantz, S.; Brooks, T.; Leon, C.; Waldhoff, S.; Edmonds, J.

2013-12-01

Future scenarios, such as the Representative Concentration Pathways (RCPs), are typically designed to meet a radiative forcing target while also producing enough food and energy for a growing population. In the assessment process, impacts of these scenarios for other important variables such as biodiversity loss are considered 'downstream', after the future climate has been simulated within Earth System Models. However, the direct land-use impacts associated with future scenarios often have as much impact on these issues as the changing climate; in addition, many different patterns of land-use can result in the same radiative forcing target. In the case of biodiversity loss, one of the greatest contributors to species extinction is the loss of habitat such as primary forest, which is a direct result of land-use change decisions. By considering issues such as the preservation of future biodiversity 'up-front' in the scenario process, we can design a scenario that not only meets a radiative forcing target and feeds a growing planet, but also preserves as much habitat as possible through careful spatial allocation of future land-use change. Our Global Land-use Model (GLM) is used to provide 'harmonized' land-use data for the RCP process. GLM preserves as much information as possible from the Integrated Assessment Models (IAMs) while spatially allocating regional IAM land-use change data, ensuring a continuous transition from historical to future land-use states, and producing annual, gridded (0.5°×0.5°), fractional land-use states and all associated transitions. In this presentation we will present results from new GLM simulations in which land-use change decisions are constrained to meet the mutual goals of protecting important eco-regions (e.g. biodiversity hotspots) from future land-use change, providing enough food and fiber for a growing planet, and remaining consistent with the radiative forcing targets of the future scenarios. Trade-offs between agricultural

The Future Is Bright and Predictable: The Development of Prospective Life Stories across Childhood and Adolescence

ERIC Educational Resources Information Center

Bohn, Annette; Berntsen, Dorthe

2013-01-01

When do children develop the ability to imagine their future lives in terms of a coherent prospective life story? We investigated whether this ability develops in parallel with the ability to construct a life story for the past and narratives about single autobiographical events in the past and future. Four groups of school children aged 9 to 15…

NASA Future Forum

NASA Image and Video Library

2012-02-21

Dr. Caroline Wagner, associate professor, Ambassador Milton A. and Roslyn Z. Wolf Chair in International Affairs, and Director, Battelle Center for Science and Technology Policy, The Ohio State University moderates the NASA Future Forum panel titled "Shifting Roles for Public, Private, and International Players in Space" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

An Introduction to Educational Futures.

ERIC Educational Resources Information Center

Beane, James; And Others

The purpose of this paper is to provide an introduction to the field of educational futures. It describes a framework for educational futures that moves from the understanding of global futures data to action planning for dealing with the understanding those data have for education. The paper discusses the future of government, life styles, and…

Conjunctive management of surface and groundwater resources under projected future climate change scenarios

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mani, Amir; Tsai, Frank T. -C.; Kao, Shih-Chieh

Our study introduces a mixed integer linear fractional programming (MILFP) method to optimize conjunctive use of future surface water and groundwater resources under projected climate change scenarios. The conjunctive management model maximizes the ratio of groundwater usage to reservoir water usage. Future inflows to the reservoirs were estimated from the future runoffs projected through hydroclimate modeling considering the Variable Infiltration Capacity model, and 11 sets of downscaled Coupled Model Intercomparison Project phase 5 global climate model projections. Bayesian model averaging was adopted to quantify uncertainty in future runoff projections and reservoir inflow projections due to uncertain future climate projections. Optimizedmore » conjunctive management solutions were investigated for a water supply network in northern Louisiana which includes the Sparta aquifer. Runoff projections under climate change scenarios indicate that runoff will likely decrease in winter and increase in other seasons. Ultimately, results from the developed conjunctive management model with MILFP indicate that the future reservoir water, even at 2.5% low inflow cumulative probability level, could counterbalance groundwater pumping reduction to satisfy demands while improving the Sparta aquifer through conditional groundwater head constraint.« less

Adaptive false memory: Imagining future scenarios increases false memories in the DRM paradigm.

PubMed

Dewhurst, Stephen A; Anderson, Rachel J; Grace, Lydia; van Esch, Lotte

2016-10-01

Previous research has shown that rating words for their relevance to a future scenario enhances memory for those words. The current study investigated the effect of future thinking on false memory using the Deese/Roediger-McDermott (DRM) procedure. In Experiment 1, participants rated words from 6 DRM lists for relevance to a past or future event (with or without planning) or in terms of pleasantness. In a surprise recall test, levels of correct recall did not vary between the rating tasks, but the future rating conditions led to significantly higher levels of false recall than the past and pleasantness conditions did. Experiment 2 found that future rating led to higher levels of false recognition than did past and pleasantness ratings but did not affect correct recognition. The effect in false recognition was, however, eliminated when DRM items were presented in random order. Participants in Experiment 3 were presented with both DRM lists and lists of unrelated words. Future rating increased levels of false recognition for DRM lures but did not affect correct recognition for DRM or unrelated lists. The findings are discussed in terms of the view that false memories can be associated with adaptive memory functions.

Conjunctive management of surface and groundwater resources under projected future climate change scenarios

DOE PAGES

Mani, Amir; Tsai, Frank T. -C.; Kao, Shih-Chieh; ...

2016-06-16

Our study introduces a mixed integer linear fractional programming (MILFP) method to optimize conjunctive use of future surface water and groundwater resources under projected climate change scenarios. The conjunctive management model maximizes the ratio of groundwater usage to reservoir water usage. Future inflows to the reservoirs were estimated from the future runoffs projected through hydroclimate modeling considering the Variable Infiltration Capacity model, and 11 sets of downscaled Coupled Model Intercomparison Project phase 5 global climate model projections. Bayesian model averaging was adopted to quantify uncertainty in future runoff projections and reservoir inflow projections due to uncertain future climate projections. Optimizedmore » conjunctive management solutions were investigated for a water supply network in northern Louisiana which includes the Sparta aquifer. Runoff projections under climate change scenarios indicate that runoff will likely decrease in winter and increase in other seasons. Ultimately, results from the developed conjunctive management model with MILFP indicate that the future reservoir water, even at 2.5% low inflow cumulative probability level, could counterbalance groundwater pumping reduction to satisfy demands while improving the Sparta aquifer through conditional groundwater head constraint.« less

Making Geographical Futures

ERIC Educational Resources Information Center

Morgan, John

2015-01-01

Although there are surprisingly few academic books about geography with the term "future" or "futures" in their titles, this paper indicates that for much of the twentieth century geographers contributed to important discussions about the shape of worlds to come. The paper offers a review of these debates within Anglo-American…

Winning the Future: An Investigation into the Creativity Capacity across the Levels of Education in Ireland

ERIC Educational Resources Information Center

Leahy, Keelin

2016-01-01

This research investigated the creativity capacity across the levels of education in Ireland, involving 702 participants. Creative capacity was investigated through a comparative analysis of creativity quotient (CQ). A divergent thinking task comprising the "how many uses" activity was assessed using the criteria for determining CQ;…

Future states: the axioms underlying prospective, future-oriented, health planning instruments.

PubMed

Koch, T

2001-02-01

Proscriptive planning exercises are critical to and generally accepted as integral to health planning at varying scales. These require specific instruments designed to predict future actions on the basis of present knowledge. At the macro-level of health economics, for example, a number of future-oriented Quality of Life Instruments (QL) are commonly employed. At the level of individual decision making, on the other hand, Advance Directives (AD's) are advanced as a means by which healthy individuals can assure their wishes will be carried out if at some future point they are incapacitated. As proscriptive tools, both instrument classes appear to share an axiomatic set whose individual parts have not been rigorously considered. This paper attempts to first identify and then consider a set of five axioms underlying future oriented health planning instruments. These axioms are then critiqued using data from a pre-test survey designed specifically to address their assumptions. Results appear to challenge the validity of the axioms underlying the proscriptive planning instruments.

How will SOA change in the future?: SOA IN THE FUTURE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Guangxing; Penner, Joyce E.; Zhou, Cheng

2016-02-17

Secondary organic aerosol (SOA) plays a significant role in the Earth system by altering its radiative balance. Here we use an Earth system model coupled with an explicit SOA formation module to estimate the response of SOA concentrations to changes in climate, anthropogenic emissions, and human land use in the future. We find that climate change is the major driver for SOA change under the representative concentration pathways for the 8.5 future scenario. Climate change increases isoprene emission rate by 18% with the effect of temperature increases outweighing that of the CO2 inhibition effect. Annual mean global SOA mass ismore » increased by 25% as a result of climate change. However, anthropogenic emissions and land use change decrease SOA. The net effect is that future global SOA burden in 2100 is nearly the same as that of the present day. The SOA concentrations over the Northern Hemisphere are predicted to decline in the future due to the control of sulfur emissions.« less

Future health-related behavioral intention formation: the role of affect and cognition.

PubMed

Richardson, Jessica G; Trafimow, David; Madson, Laura

2012-01-01

This study investigated the differential contribution of affect and cognition to behavioral intention formation during pursuit of future health-related goals. Cognitive evaluations, affective evaluations and behavioral intentions were measured for each of 32 health-related behaviors. The timeframes of the cognitive/affective measures and the behavioral intention measure were varied between current and future timeframes creating four different conditions. Within-participants correlations between affect and intentions and cognition and intentions were calculated to determine the contribution of each factor to behavioral intention formation in the different timeframes. Results did not support the hypothesis that a shift from a reliance on affect to a reliance on cognition would occur as temporal distance increased. Within-participants analyses revealed a decrease in the contribution of cognition to behavioral intention formation when forming attitudes in the future condition.

Experiencing Past and Future Personal Events: Functional Neuroimaging Evidence on the Neural Bases of Mental Time Travel

ERIC Educational Resources Information Center

Botzung, Anne; Denkova, Ekaterina; Manning, Lilianne

2008-01-01

Functional MRI was used in healthy subjects to investigate the existence of common neural structures supporting re-experiencing the past and pre-experiencing the future. Past and future events evocation appears to involve highly similar patterns of brain activation including, in particular, the medial prefrontal cortex, posterior regions and the…

Queerin' the PGD clinic : human enhancement and the future of bodily diversity.

PubMed

Sparrow, Robert

2013-06-01

Disability activists influenced by queer theory and advocates of "human enhancement" have each disputed the idea that what is "normal" is normatively significant, which currently plays a key role in the regulation of pre-implantation genetic diagnosis (PGD). Previously, I have argued that the only way to avoid the implication that parents have strong reasons to select children of one sex (most plausibly, female) over the other is to affirm the moral significance of sexually dimorphic human biological norms. After outlining the logic that generates this conclusion, I investigate the extent to which it might also facilitate an alternative, progressive, opening up of the notion of the normal and of the criteria against which we should evaluate the relative merits of different forms of embodiment. This paper therefore investigates the implications of ideas derived from queer theory for the future of PGD and of PGD for the future of queerness.

Future singularities and teleparallelism in loop quantum cosmology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bamba, Kazuharu; Haro, Jaume de; Odintsov, Sergei D., E-mail: bamba@kmi.nagoya-u.ac.jp, E-mail: jaime.haro@upc.edu, E-mail: odintsov@ieec.uab.es

2013-02-01

We demonstrate how holonomy corrections in loop quantum cosmology (LQC) prevent the Big Rip singularity by introducing a quadratic modification in terms of the energy density ρ in the Friedmann equation in the Friedmann-Lemaître-Robertson-Walker (FLRW) space-time in a consistent and useful way. In addition, we investigate whether other kind of singularities like Type II,III and IV singularities survive or are avoided in LQC when the universe is filled by a barotropic fluid with the state equation P = −ρ−f(ρ), where P is the pressure and f(ρ) a function of ρ. It is shown that the Little Rip cosmology does notmore » happen in LQC. Nevertheless, the occurrence of the Pseudo-Rip cosmology, in which the phantom universe approaches the de Sitter one asymptotically, is established, and the corresponding example is presented. It is interesting that the disintegration of bound structures in the Pseudo-Rip cosmology in LQC always takes more time than that in Einstein cosmology. Our investigation on future singularities is generalized to that in modified teleparallel gravity, where LQC and Brane Cosmology in the Randall-Sundrum scenario are the best examples. It is remarkable that F(T) gravity may lead to all the kinds of future singularities including Little Rip.« less

Influence of outcome valence in the subjective experience of episodic past, future, and counterfactual thinking.

PubMed

De Brigard, Felipe; Giovanello, Kelly S

2012-09-01

Recent findings suggest that our capacity to imagine the future depends on our capacity to remember the past. However, the extent to which episodic memory is involved in our capacity to think about what could have happened in our past, yet did not occur (i.e., episodic counterfactual thinking), remains largely unexplored. The current experiments investigate the phenomenological characteristics and the influence of outcome valence on the experience of past, future and counterfactual thoughts. Participants were asked to mentally simulate past, future, and counterfactual events with positive or negative outcomes. Features of their subjective experiences during each type of simulation were measured using questionnaires and autobiographical interviews. The results suggest that clarity and vividness were higher for past than future and counterfactual simulations. Additionally, emotional intensity was lower for counterfactual simulations than past and future simulations. Finally, outcome valence influenced participants' judgment of probability for future and counterfactual simulations. Copyright © 2012 Elsevier Inc. All rights reserved.

Future leisure environments

Treesearch

Elwood L. Shafer; George H. Moeller; Russell E. Getty

1974-01-01

As an aid to policy- and decision-making about future environmental problems, a panel of experts was asked to predict the probabilities of future events associated with natural-resource management, wildland-recreation management, environmental pollution, population-workforce-leisure, and urban environments. Though some of the predictions projected to the year 2050 may...

The Futuring Process

Treesearch

Delmer L. Albright

1987-01-01

Futuring" is becoming a widely accepted approach to organization management and goal setting. Strategic planners for the United States military as well as the Forest Service, U.S. Department of Agriculture, and the California Department of Forestry and Fire Protection, use Futuring to develop action plans and organizational directions for their agencies.

[Nephrology as seen by nephrologists. An introspective investigation into the history and future of the professional community].

PubMed

Susi, Alessandra

2010-01-01

The professional community of nephrologists is going through a phase of ''rethinking'' the discipline that sees the role of nephrologists in an uncertain position between inpatient and outpatient care. A comparison of opinions within the community is necessary to understand what could be the future position of nephrology in the Italian healthcare system. In June 2009 a questionnaire was distributed among the members of the Italian Nephrology Society (SIN) to collect (i) their professional biographies and (ii) their opinion on the state of the art of nephrology, (iii) the working context in which they operate, (iv) the likely sources of change, and (v) the prospects for the development of the field. In October 2009 the respondents were 506, a sufficiently representative sample of the national population of nephrologists. One of the main findings was a lack of consensus about the clinical practice for the treatment of CKD. In particular, there was no general agreement about the stage of CKD at which the patient should enter the exclusive care of the nephrologist. Opinions were less divergent on (i) departmentalization phenomena, (ii) the outsourcing of dialysis services, and (iii) the future prospects of the specialty. In order to pursue common goals for the development of the discipline, the internal relations of the professional community should be strengthened both in terms of sharing clinical experience and defining the roles of clinicians within the community. The involvement of young nephrologists in the definition of strategies for the positioning of nephrology in the Italian healthcare system might also be considered a priority.

Concern or confidence? Adolescents' identity capital and future worry in different school contexts.

PubMed

Tikkanen, Jenni

2016-01-01

This present study investigated the roles identity capital and school's socio-economic status have on adolescent worry about future education, employment, and social status. The 354 participants were 14- to 15-year-old students from affluent (56.8%) and disadvantaged (43.2%) Finnish lower secondary schools. Structural equation modelling was used to test the hypothesis that a higher level of family-related identity capital is connected to a lower level of future worry, and that this connection is mediated through intrapersonal forms of identity capital, specifically academic self-concept and general self-efficacy. Adolescent future worry was also examined across school status with an independent samples t-test. The findings suggest that, in the relatively equal societal context in Finland, adolescents are rather confident about their future education, employment, and social status regardless of the socio-economic status of the school they attend, and when their level of identity capital is high the future worry decreases further. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Well-being and Anticipation for Future Positive Events: Evidences from an fMRI Study.

PubMed

Luo, Yangmei; Chen, Xuhai; Qi, Senqing; You, Xuqun; Huang, Xiting

2017-01-01

Anticipation for future confers great benefits to human well-being and mental health. However, previous work focus on how people's well-being correlate with brain activities during perception of emotional stimuli, rather than anticipation for the future events. Here, the current study investigated how well-being relates to neural circuitry underlying the anticipating process of future desired events. Using event-related functional magnetic resonance imaging, 40 participants were scanned while they were performing an emotion anticipation task, in which they were instructed to anticipate the positive or neutral events. The results showed that bilateral medial prefrontal cortex (MPFC) were activated during anticipation for positive events relative to neutral events, and the enhanced brain activation in MPFC was associated with higher level of well-being. The findings suggest a neural mechanism by which the anticipation process to future desired events correlates to human well-being, which provide a future-oriented view on the neural sources of well-being.

Well-being and Anticipation for Future Positive Events: Evidences from an fMRI Study

PubMed Central

Luo, Yangmei; Chen, Xuhai; Qi, Senqing; You, Xuqun; Huang, Xiting

2018-01-01

Anticipation for future confers great benefits to human well-being and mental health. However, previous work focus on how people’s well-being correlate with brain activities during perception of emotional stimuli, rather than anticipation for the future events. Here, the current study investigated how well-being relates to neural circuitry underlying the anticipating process of future desired events. Using event-related functional magnetic resonance imaging, 40 participants were scanned while they were performing an emotion anticipation task, in which they were instructed to anticipate the positive or neutral events. The results showed that bilateral medial prefrontal cortex (MPFC) were activated during anticipation for positive events relative to neutral events, and the enhanced brain activation in MPFC was associated with higher level of well-being. The findings suggest a neural mechanism by which the anticipation process to future desired events correlates to human well-being, which provide a future-oriented view on the neural sources of well-being. PMID:29375415

Scheduling Future Water Supply Investments Under Uncertainty

NASA Astrophysics Data System (ADS)

Huskova, I.; Matrosov, E. S.; Harou, J. J.; Kasprzyk, J. R.; Reed, P. M.

2014-12-01

Uncertain hydrological impacts of climate change, population growth and institutional changes pose a major challenge to planning of water supply systems. Planners seek optimal portfolios of supply and demand management schemes but also when to activate assets whilst considering many system goals and plausible futures. Incorporation of scheduling into the planning under uncertainty problem strongly increases its complexity. We investigate some approaches to scheduling with many-objective heuristic search. We apply a multi-scenario many-objective scheduling approach to the Thames River basin water supply system planning problem in the UK. Decisions include which new supply and demand schemes to implement, at what capacity and when. The impact of different system uncertainties on scheme implementation schedules are explored, i.e. how the choice of future scenarios affects the search process and its outcomes. The activation of schemes is influenced by the occurrence of extreme hydrological events in the ensemble of plausible scenarios and other factors. The approach and results are compared with a previous study where only the portfolio problem is addressed (without scheduling).

Future petroleum geologist: discussion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, G.D.

1987-07-01

Robert R. Berg's (1986) article, ''The Future Petroleum Geologist,'' summarizes the findings of the 13-member AAPG Select Committee on The Future Petroleum Geologist appointed by President William L. Fisher in July 1985. While this undertaking is laudable, particularly considering present circumstance in the petroleum industry, the committee has apparently overlooked a vital aspect concerning the future knowledge requirements of the petroleum geologist. Specifically, the Select Committee makes no mention of the need for computer literacy in its list of educational training categories. Obviously, AAPG is well aware of both the interest in computers by its membership and the increasing needmore » for training and familiarity in this discipline. The Select Committee on The Future Petroleum Geologist, while undertaking a difficult and potentially controversial task, has omitted an important aspect of the background requirements for generations of future petroleum geologists; the committee should consider an amendment to their recommendations to reflect this increasingly important field study.« less

Important Competencies for Future Health and Wellness Professionals: An Investigation of Employer Desired Skills

ERIC Educational Resources Information Center

Becker, Craig; Loy, Marty

2004-01-01

This study was designed to investigate the validity of the professional competencies developed by the Association of Worksite Health Promotion (AWHP) Professional Standards Task Force. The Task Force identified a competency framework that included business skills, program coordination skills, and human resource skills with corresponding…

Meat and heme iron intake and risk of squamous cell carcinoma of the upper aero-digestive tract in the European Prospective Investigation into Cancer and Nutrition (EPIC)

PubMed Central

Steffen, Annika; Bergmann, Manuela M.; Sánchez, María-José; Chirlaque, Maria-Dolores; Jakszyn, Paula; Amiano, Pilar; Quirós, J. Ramón; Gurrea, Aurelio Barricarte; Ferrari, Pietro; Romieu, Isabelle; Fedirko, Veronika; Bueno-de-Mesquita, H. B(as).; Siersema, Peter D.; Peeters, Petra HM; Khaw, Kay-Tee; Wareham, Nick; Allen, Naomi E.; Crowe, Francesca L.; Skeie, Guri; Hallmanns, Göran; Johansson, Ingegerd; Borgquist, Signe; Ericson, Ulrika; Egeberg, Rikke; Tjønneland, Anne; Overvad, Kim; Grote, Verena; Li, Kuanrong; Trichopoulou, Antonia; Oikonomidou, Despoina; Pantzalis, Menelaos; Tumino, Rosario; Panico, Salvatore; Palli, Domenico; Krogh, Vittorio; Naccarati, Alessio; Mouw, Traci; Vergnaud, Anne-Claire; Norat, Teresa; Boeing, Heiner

2012-01-01

Background Evidence from prospective studies on intake of meat and fish and risk of squamous cell carcinoma (SCC) of the upper aero-digestive tract (UADT) is scarce. We prospectively investigated the association of meat and fish intake with risk of SCC of the UADT and the possible mechanism via heme iron in the large multi-center European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods Multivariable proportional hazards models were used to estimate relative risks of SCC of the UADT in relation to intake of total meat, as well as subtypes of meat, fish and heme iron among 348,738 individuals from 7 European countries. Results During an average follow-up of 11.8 years, a total of 682 incident cases of UADT SCC were accrued. Intake of processed meat was positively associated with risk of SCC of the UADT in the total cohort (highest versus lowest quintile: RR=1.41; 95% CI=1.03-1.94), however, in stratified analyses, this association was confined to the group of current smokers (highest versus lowest quintile: RR=1.89; 95% CI=1.22-2.93). Red meat, poultry, fish and heme iron were not consistently related to UADT SCC. Conclusion Higher intake of processed meat was positively associated with SCC of the UADT among smokers. Although this finding was stable in various sensitivity analyses, we cannot rule out residual confounding by smoking. Confirmation in future studies and identification of biological mechanisms is warranted. Impact Smokers may further increase their risk for SCC of the UADT if they additionally consume large amounts of processed meat. PMID:23033453

Children's Predictions of Future Perceptual Experiences: Temporal Reasoning and Phenomenology

ERIC Educational Resources Information Center

Burns, Patrick; Russell, James

2016-01-01

We investigated the development and cognitive correlates of envisioning future experiences in 3.5- to 6.5-year old children across 2 experiments, both of which involved toy trains traveling along a track. In the first, children were asked to predict the direction of train travel and color of train side, as it would be seen through an arch.…

Digital Geological Map for Marie Byrd Land, West Antarctica: A resource for investigation of geotectonic frameworks and future glaciological change

NASA Astrophysics Data System (ADS)

Siddoway, C. S.; White, T.; Elkind, S.; Cox, S. C.; Lyttle, B. S.; Morin, P. J.

2016-12-01

Bedrock exposures are relatively sparse in Marie Byrd Land (MBL), where rock is concealed by the West Antarctic ice sheet, but they provide direct insight into the geological evolution and glacial history of West Antarctica. MBL is tectonically active, as evidenced by Late Pleistocene to Holocene volcanism and 2012 seismicity (3 events, M4.4 to M5.5) at sites beside Ross Sea. There are geological influences upon the ice sheet, namely, subglacial volcanism and associated geothermal flux, fault zone alteration/mineralization, and bedrock roughess. The former may influence the position and velocity of outlet glaciers and the latter may anchor or accelerate sectors of the ice sheet. To make MBL's geological framework accessible to investigators with diverse research priorities, we are preparing the first digital geological map of MBL by compiling ground-based geological data, incorporating firsthand observations, published geological maps and literature. The map covers an on-continent coastal area of 900 000 km2 between 090°E to 160°E, from 72°S to 80°S, at 1:250 000 scale or better. Exposed rock is delimited by 1976 polygons, occupying 410 km2. Supraglacial features and glacial till, seasonal water and blue ice, are also mapped, as a baseline for past and future glaciological change. Rendered in the ArcMap GIS software by Esri©, the database employs international GeoSciML data protocols for feature classification and description of rock and moraine polygons from the Antarctic Digital Database (www.add.scar.org), with shape and location adjusted to align with features in Landsat Image Mosaic of Antarctica imagery (lima.usgs.gov), where necessary. The GIS database is attribute-rich and queriable; including links to bibliographic source files for primary literature and published maps. It will soon be available as GoogleEarth kmz files and an ArcGIS online map service. An initial application is to the interpretation of sub-ice geology for a subglacial geotectonic map

Idaho's Library Future.

ERIC Educational Resources Information Center

Idaho State Library, Boise.

In l998, Idahoans gathered in a series of six Regional Futures Conferences to identify what they thought was probable during the next ten years, what was possible for libraries to do and be, and what a preferred future of Idaho libraries might be. Participants from the regional conferences then convened to refine and focus descriptions of the…

Scripts and information units in future planning: Interactions between a past and a future planning task.

PubMed

Cordonnier, Aline; Barnier, Amanda J; Sutton, John

2016-01-01

Research on future thinking has emphasized how episodic details from memories are combined to create future thoughts, but has not yet examined the role of semantic scripts. In this study, participants recalled how they planned a past camping trip in Australia (past planning task) and imagined how they would plan a future camping trip (future planning task), set either in a familiar (Australia) or an unfamiliar (Antarctica) context. Transcripts were segmented into information units that were coded according to semantic category (e.g., where, when, transport, material, actions). Results revealed a strong interaction between tasks and their presentation order. Starting with the past planning task constrained the future planning task when the context was familiar. Participants generated no new information when the future camping trip was set in Australia and completed second (after the past planning task). Conversely, starting with the future planning task facilitated the past planning task. Participants recalled more information units of their past plan when the past planning task was completed second (after the future planning task). These results shed new light on the role of scripts in past and future thinking and on how past and future thinking processes interact.