Sample records for waveguide-based optical biosensor

  1. Label-free silicon photonic biosensor system with integrated detector array.

    PubMed

    Yan, Rongjin; Mestas, Santano P; Yuan, Guangwei; Safaisini, Rashid; Dandy, David S; Lear, Kevin L

    2009-08-07

    An integrated, inexpensive, label-free photonic waveguide biosensor system with multi-analyte capability has been implemented on a silicon photonics integrated circuit from a commercial CMOS line and tested with nanofilms. The local evanescent array coupled (LEAC) biosensor is based on a new physical phenomenon that is fundamentally different from the mechanisms of other evanescent field sensors. Increased local refractive index at the waveguide's upper surface due to the formation of a biological nanofilm causes local modulation of the evanescent field coupled into an array of photodetectors buried under the waveguide. The planar optical waveguide biosensor system exhibits sensitivity of 20%/nm photocurrent modulation in response to adsorbed bovine serum albumin (BSA) layers less than 3 nm thick. In addition to response to BSA, an experiment with patterned photoresist as well as beam propagation method simulations support the evanescent field shift principle. The sensing mechanism enables the integration of all optical and electronic components for a multi-analyte biosensor system on a chip.

  2. Fiber Optic Surface Plasmon Resonance-Based Biosensor Technique: Fabrication, Advancement, and Application.

    PubMed

    Liang, Gaoling; Luo, Zewei; Liu, Kunping; Wang, Yimin; Dai, Jianxiong; Duan, Yixiang

    2016-05-03

    Fiber optic-based biosensors with surface plasmon resonance (SPR) technology are advanced label-free optical biosensing methods. They have brought tremendous progress in the sensing of various chemical and biological species. This review summarizes four sensing configurations (prism, grating, waveguide, and fiber optic) with two ways, attenuated total reflection (ATR) and diffraction, to excite the surface plasmons. Meanwhile, the designs of different probes (U-bent, tapered, and other probes) are also described. Finally, four major types of biosensors, immunosensor, DNA biosensor, enzyme biosensor, and living cell biosensor, are discussed in detail for their sensing principles and applications. Future prospects of fiber optic-based SPR sensor technology are discussed.

  3. Label-free silicon photonic biosensor system with integrated detector array

    PubMed Central

    Yan, Rongjin; Mestas, Santano P.; Yuan, Guangwei; Safaisini, Rashid; Dandy, David S.

    2010-01-01

    An integrated, inexpensive, label-free photonic waveguide biosensor system with multi-analyte capability has been implemented on a silicon photonics integrated circuit from a commercial CMOS line and tested with nanofilms. The local evanescent array coupled (LEAC) biosensor is based on a new physical phenomenon that is fundamentally different from the mechanisms of other evanescent field sensors. Increased local refractive index at the waveguide’s upper surface due to the formation of a biological nanofilm causes local modulation of the evanescent field coupled into an array of photodetectors buried under the waveguide. The planar optical waveguide biosensor system exhibits sensitivity of 20%/nm photocurrent modulation in response to adsorbed bovine serum albumin (BSA) layers less than 3 nm thick. In addition to response to BSA, an experiment with patterned photoresist as well as beam propagation method simulations support the evanescent field shift principle. The sensing mechanism enables the integration of all optical and electronic components for a multi-analyte biosensor system on a chip. PMID:19606292

  4. Biolayer modeling and optimization for the SPARROW biosensor

    NASA Astrophysics Data System (ADS)

    Feng, Ke

    2007-12-01

    Biosensor direct detection of molecular binding events is of significant interest in applications from molecular screening for cancer drug design to bioagent detection for homeland security and defense. The Stacked Planar Affinity Regulated Resonant Optical Waveguide (SPARROW) structure based on coupled waveguides was recently developed to achieve increased sensitivity within a fieldable biosensor device configuration. Under ideal operating conditions, modification of the effective propagation constant of the structure's sensing waveguide through selective attachment of specific targets to probes on the waveguide surface results in a change in the coupling characteristics of the guide over a specifically designed interaction length with the analyte. Monitoring the relative power in each waveguide after interaction enables 'recognition' of those targets which have selectively bound to the surface. However, fabrication tolerances, waveguide interface roughness, biolayer surface roughness and biolayer partial coverage have an effect on biosensor behavior and achievable limit of detection (LOD). In addition to these influences which play a role in device optimization, the influence of the spatially random surface loading of molecular binding events has to be considered, especially for low surface coverage. In this dissertation an analytic model is established for the SPARROW biosensor which accounts for these nonidealities with which the design of the biosensor can be guided and optimized. For the idealized case of uniform waveguide transducer layers and biolayer, both theoretical simulation (analytical expression) and computer simulation (numerical calculation) are completed. For the nonideal case of an inhomogeneous transducer with nonideal waveguide and biolayer surfaces, device output power is affected by such physical influences as surface scattering, coupling length, absorption, and percent coverage of binding events. Using grating and perturbation techniques we explore the influence of imperfect surfaces and random surface loading on scattering loss and coupling length. Results provide a range of achievable limits of detection in the SPARROW device for a given target size, surface loading, and detectable optical power.

  5. Thin Hydrogel Films for Optical Biosensor Applications

    PubMed Central

    Mateescu, Anca; Wang, Yi; Dostalek, Jakub; Jonas, Ulrich

    2012-01-01

    Hydrogel materials consisting of water-swollen polymer networks exhibit a large number of specific properties highly attractive for a variety of optical biosensor applications. This properties profile embraces the aqueous swelling medium as the basis of biocompatibility, non-fouling behavior, and being not cell toxic, while providing high optical quality and transparency. The present review focuses on some of the most interesting aspects of surface-attached hydrogel films as active binding matrices in optical biosensors based on surface plasmon resonance and optical waveguide mode spectroscopy. In particular, the chemical nature, specific properties, and applications of such hydrogel surface architectures for highly sensitive affinity biosensors based on evanescent wave optics are discussed. The specific class of responsive hydrogel systems, which can change their physical state in response to externally applied stimuli, have found large interest as sophisticated materials that provide a complex behavior to hydrogel-based sensing devices. PMID:24957962

  6. High sensitivity optical biosensor based on polymer materials and using the Vernier effect.

    PubMed

    Azuelos, Paul; Girault, Pauline; Lorrain, Nathalie; Poffo, Luiz; Guendouz, Mohammed; Thual, Monique; Lemaître, Jonathan; Pirasteh, Parastesh; Hardy, Isabelle; Charrier, Joël

    2017-11-27

    We demonstrate the fabrication of a Vernier effect SU8/PMATRIFE polymer optical biosensor with high homogeneous sensitivity using a standard photolithography process. The sensor is based on one micro-resonator embedded on each arm of a Mach-Zehnder interferometer. Measurements are based on the refractive index variation of the optical waveguide superstrate with different concentrations of glucose solutions. The sensitivity of the sensor has been measured as 17558 nm/RIU and the limit of detection has been estimated to 1.1.10 -6 RIU.

  7. Label-free optical biosensing with slot-waveguides.

    PubMed

    Barrios, Carlos A; Bañuls, María José; González-Pedro, Victoria; Gylfason, Kristinn B; Sánchez, Benito; Griol, Amadeu; Maquieira, A; Sohlström, H; Holgado, M; Casquel, R

    2008-04-01

    We demonstrate label-free molecule detection by using an integrated biosensor based on a Si(3)N(4)/SiO(2) slot-waveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/(ng/mm(2)) for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm(2) for anti-BSA and BSA, respectively, limited by wavelength resolution.

  8. Guided-Wave Optical Biosensors

    PubMed Central

    Passaro, Vittorio M. N.; Dell'Olio, Francesco; Casamassima, Biagio; De Leonardis, Francesco

    2007-01-01

    Guided-wave optical biosensors are reviewed in this paper. Advantages related to optical technologies are presented and integrated architectures are investigated in detail. Main classes of bio receptors and the most attractive optical transduction mechanisms are discussed. The possibility to use Mach-Zehnder and Young interferometers, microdisk and microring resonators, surface plasmon resonance, hollow and antiresonant waveguides, and Bragg gratings to realize very sensitive and selective, ultra-compact and fast biosensors is discussed. Finally, CMOS-compatible technologies are proved to be the most attractive for fabrication of guided-wave photonic biosensors.

  9. Application of microstructural optical waveguides with hollow core for enzyme immunoassay

    NASA Astrophysics Data System (ADS)

    Pidenko, Pavel S.; Pidenko, Sergei A.; Burmistrova, Natalia A.; Shuvalov, Andrei A.; Chibrova, Anastasiya A.; Skibina, Yulia S.; Goryacheva, Irina Y.

    2018-04-01

    Microstructural optical waveguides with the hollow core are actively studied as a promising support for heterogeneous immunoassay in development of new optical biosensor elements for medicine and biology. Overcoming of the limitations associated with the low sorption capacity of glass used for the waveguides production is a crucial step for this assay format. In this work the possibility of silanization of microstructural optical waveguides with the hollow core using (3-glycidyloxypropyl) trimethoxysilane and their further application to enzymatic immunoassay was studied.

  10. Toward photostable multiplex analyte detection on a single mode planar optical waveguide

    NASA Astrophysics Data System (ADS)

    Mukundan, Harshini; Xie, Hongzhi; Anderson, Aaron; Grace, W. Kevin; Martinez, Jennifer S.; Swanson, Basil

    2009-02-01

    We have developed a waveguide-based optical biosensor for the sensitive and specific detection of biomarkers associated with disease. Our technology combines the superior optical properties of single-mode planar waveguides, the robust nature of functionalized self-assembled monolayer sensing films and the specificity of fluorescence sandwich immunoassays to detect biomarkers in complex biological samples such as serum, urine and sputum. We have previously reported the adaptation of our technology to the detection of biomarkers associated with breast cancer and anthrax. However, these approaches primarily used phospholipid bilayers as the functional film and organic dyes (ex: AlexaFluors) as the fluorescence reporter. Organic dyes are easily photodegraded and are not amenable to multiplexing because of their narrow Stokes' shift. Here we have developed strategies for conjugation of the detector antibodies with quantum dots for use in a multiplex detection platform. We have previously evaluated dihydroxylipoic acid quantum dots for the detection of a breast cancer biomarker. In this manuscript, we investigate the detection of the Bacillus anthracis protective antigen using antibodies conjugated with polymer-coated quantum dots. Kinetics of binding on the waveguide-based biosensor is reported. We compare the sensitivity of quantum dot labeled antibodies to those labeled with AlexaFluor and demonstrate the photostability of the former in our assay platform. In addition, we compare sulfydryl labeling of the antibody in the hinge region to that of nonspecific amine labeling. This is but the first step in developing a multiplex assay for such biomarkers on our waveguide platform.

  11. Hybrid optofluidic biosensors

    NASA Astrophysics Data System (ADS)

    Parks, Joshua W.

    Optofluidics, born of the desire to create a system containing microfluidic environments with integrated optical elements, has seen dramatic increases in popularity over the last 10 years. In particular, the application of this technology towards chip based molecular sensors has undergone significant development. The most sensitive of these biosensors interface liquid- and solid-core antiresonant reflecting optical waveguides (ARROWs). These sensor chips are created using conventional silicon microfabrication. As such, ARROW technology has previously been unable to utilize state-of-the-art microfluidic developments because the technology used--soft polydimethyl siloxane (PDMS) micromolded chips--is unamenable to the silicon microfabrication workflows implemented in the creation of ARROW detection chips. The original goal of this thesis was to employ hybrid integration, or the connection of independently designed and fabricated optofluidic and microfluidic chips, to create enhanced biosensors with the capability of processing and detecting biological samples on a single hybrid system. After successful demonstration of this paradigm, this work expanded into a new direction--direct integration of sensing and detection technologies on a new platform with dynamic, multi-dimensional photonic re-configurability. This thesis reports a number of firsts, including: • 1,000 fold optical transmission enhancement of ARROW optofluidic detection chips through thermal annealing, • Detection of single nucleic acids on a silicon-based ARROW chip, • Hybrid optofluidic integration of ARROW detection chips and passive PDMS microfluidic chips, • Hybrid optofluidic integration of ARROW detection chips and actively controllable PDMS microfluidic chips with integrated microvalves, • On-chip concentration and detection of clinical Ebola nucleic acids, • Multimode interference (MMI) waveguide based wavelength division multiplexing for detection of single influenza virions, • All PDMS platform created from monolithically integrated solid- and liquid-core waveguides with single particle detection efficiency and directly integrated microvalves, featuring: ∘ Tunable/tailorable PDMS MMI waveguides, ∘ Lightvalves (optical switch/fluidic microvalve) with the ability to dynamically control light and fluid flow simultaneously, ∘ Lightvalve trap architecture with the ability to physically trap, detect, and analyze single biomolecules.

  12. Dispersion characteristics of plasmonic waveguides for THz waves

    NASA Astrophysics Data System (ADS)

    Markides, Christos; Viphavakit, Charusluk; Themistos, Christos; Komodromos, Michael; Kalli, Kyriacos; Quadir, Anita; Rahman, Azizur

    2013-05-01

    Today there is an increasing surge in Surface Plasmon based research and recent studies have shown that a wide range of plasmon-based optical elements and techniques have led to the development of a variety of active switches, passive waveguides, biosensors, lithography masks, to name just a few. The Terahertz (THz) frequency region of the electromagnetic spectrum is located between the traditional microwave spectrum and the optical frequencies, and offers a significant scientific and technological potential in many fields, such as in sensing, in imaging and in spectroscopy. Waveguiding in this intermediate spectral region is a major challenge. Amongst the various THz waveguides suggested, the metal-clad waveguides supporting surface plasmon modes waves and specifically hollow core structures, coated with insulating material are showing the greatest promise as low-loss waveguides for their use in active components and as well as passive waveguides. The H-field finite element method (FEM) based full-vector formulation is used to study the vectorial modal field properties and the complex propagation characteristics of Surface Plasmon modes of a hollow-core dielectric coated rectangular waveguide structure. Additionally, the finite difference time domain (FDTD) method is used to estimate the dispersion parameters and the propagation loss of the rectangular waveguide.

  13. Optical biosensor technologies for molecular diagnostics at the point-of-care

    NASA Astrophysics Data System (ADS)

    Schotter, Joerg; Schrittwieser, Stefan; Muellner, Paul; Melnik, Eva; Hainberger, Rainer; Koppitsch, Guenther; Schrank, Franz; Soulantika, Katerina; Lentijo-Mozo, Sergio; Pelaz, Beatriz; Parak, Wolfgang; Ludwig, Frank; Dieckhoff, Jan

    2015-05-01

    Label-free optical schemes for molecular biosensing hold a strong promise for point-of-care applications in medical research and diagnostics. Apart from diagnostic requirements in terms of sensitivity, specificity, and multiplexing capability, also other aspects such as ease of use and manufacturability have to be considered in order to pave the way to a practical implementation. We present integrated optical waveguide as well as magnetic nanoparticle based molecular biosensor concepts that address these aspects. The integrated optical waveguide devices are based on low-loss photonic wires made of silicon nitride deposited by a CMOS compatible plasma-enhanced chemical vapor deposition (PECVD) process that allows for backend integration of waveguides on optoelectronic CMOS chips. The molecular detection principle relies on evanescent wave sensing in the 0.85 μm wavelength regime by means of Mach-Zehnder interferometers, which enables on-chip integration of silicon photodiodes and, thus, the realization of system-on-chip solutions. Our nanoparticle-based approach is based on optical observation of the dynamic response of functionalized magneticcore/ noble-metal-shell nanorods (`nanoprobes') to an externally applied time-varying magnetic field. As target molecules specifically bind to the surface of the nanoprobes, the observed dynamics of the nanoprobes changes, and the concentration of target molecules in the sample solution can be quantified. This approach is suitable for dynamic real-time measurements and only requires minimal sample preparation, thus presenting a highly promising point-of-care diagnostic system. In this paper, we present a prototype of a diagnostic device suitable for highly automated sample analysis by our nanoparticle-based approach.

  14. Theory and Applications of Surface Plasmon Resonance, Resonant Mirror, Resonant Waveguide Grating, and Dual Polarization Interferometry Biosensors

    PubMed Central

    Daghestani, Hikmat N.; Day, Billy W.

    2010-01-01

    Biosensors have been used extensively in the scientific community for several purposes, most notably to determine association and dissociation kinetics, protein-ligand, protein-protein, or nucleic acid hybridization interactions. A number of different types of biosensors are available in the field, each with real or perceived benefits over the others. This review discusses the basic theory and operational arrangements of four commercially available types of optical biosensors: surface plasmon resonance, resonant mirror, resonance waveguide grating, and dual polarization interferometry. The different applications these techniques offer are discussed from experiments and results reported in recently published literature. Additionally, recent advancements or modifications to the current techniques are also discussed. PMID:22163431

  15. Fiber optic-based regenerable biosensor

    DOEpatents

    Sepaniak, Michael J.; Vo-Dinh, Tuan

    1993-01-01

    A fiber optic-based regenerable biosensor. The biosensor is particularly suitable for use in microscale work in situ. In one embodiment, the biosensor comprises a reaction chamber disposed adjacent the distal end of a waveguide and adapted to receive therein a quantity of a sample containing an analyte. Leading into the chamber is a plurality of capillary conduits suitable for introducing into the chamber antibodies or other reagents suitable for selective interaction with a predetermined analyte. Following such interaction, the contents of the chamber may be subjected to an incident energy signal for developing fluorescence within the chamber that is detectable via the optical fiber and which is representative of the presence, i.e. concentration, of the selected analyte. Regeneration of the biosensor is accomplished by replacement of the reagents and/or the analyte, or a combination of these, at least in part via one or more of the capillary conduits. The capillary conduits extend from their respective terminal ends that are in fluid communication with the chamber, away from the chamber to respective location(s) remote from the chamber thereby permitting in situ location of the chamber and remote manipulation and/or analysis of the activity with the chamber.

  16. Optical fiber endface biosensor based on resonances in dielectric waveguide gratings

    NASA Astrophysics Data System (ADS)

    Wawro, Debra D.; Tibuleac, Sorin; Magnusson, Robert; Liu, Hanli

    2000-05-01

    A new fiber optic sensor integrating dielectric diffraction gratings and thin films on optical fiber endfaces is prosed for biomedical sensing applications. This device utilizes a resonant dielectric waveguide grating structure fabricated on an optical fiber endface to probe reactions occurring in a sensing layer deposited on its surface. The operation of this sensor is based upon a fundamental resonance effect that occurs in waveguide gratings. An incident broad- spectrum signal is guided within an optical fiber and is filtered to reflect or transmit a desired spectral band by the diffractive thin film structure on its endface. Slight changes in one or more parameters of the waveguide grating, such as refractive index or thickness, can result in a responsive shift of the reflected or transmitted spectral peak that can be detected with spectroscopic instruments. This new sensor concept combines improved sensitivity and accuracy with attractive features found separately in currently available fiber optic sensors, such as large dynamic range, small sensing proximity, real time operation, and remote sensing. Diffractive elements of this type consisting of a photoresist grating on a Si3N4 waveguide have been fabricated on multimode optical fiber endfaces with 100 micrometers cores. Preliminary experimental tests using a tunable Ti:sapphire laser indicate notches of 18 percent in the transmission spectrum of the fiber endface guided-mode resonance devices. A theoretical analysis of the device performance capabilities is presented and applied to evaluate the feasibility and potential advantages of this bioprobe.

  17. Evanescent field Sensors Based on Tantalum Pentoxide Waveguides – A Review

    PubMed Central

    Schmitt, Katrin; Oehse, Kerstin; Sulz, Gerd; Hoffmann, Christian

    2008-01-01

    Evanescent field sensors based on waveguide surfaces play an important role where high sensitivity is required. Particularly tantalum pentoxide (Ta2O5) is a suitable material for thin-film waveguides due to its high refractive index and low attenuation. Many label-free biosensor systems such as grating couplers and interferometric sensors as well as fluorescence-based systems benefit from this waveguide material leading to extremely high sensitivity. Some biosensor systems based on Ta2O5 waveguides already took the step into commercialization. This report reviews the various detection systems in terms of limit of detection, the applications, and the suitable surface chemistry. PMID:27879731

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mukundan, Harshini; Xei, Hongshi; Anderson, Aaron S

    We have developed a waveguide-based optical biosensor for the sensitive and specific detection of biomarkers associated with disease. Our technology combines the superior optical properties of single-mode planar waveguides, the robust nature of functionalized self-assembled monolayer sensing films and the specificity of fluorescence sandwich immunoassays to detect biomarkers in complex biological samples such as serum, urine and sputum. We have previously reported the adaptation of our technology to the detection of biomarkers associated with breast cancer and anthrax. However, these approaches primarily used phospholipid bilayers as the functional film and organic dyes (ex: AlexaFluors) as the fluorescence reporter. Organic dyesmore » are easily photodegraded and are not amenable to multiplexing because of their narrow Stokes' shift. Here we have developed strategies for conjugation of the detector antibodies with quantum dots for use in a multiplex detection platform. We have previously evaluated dihydroxylipoic acid quantum dots for the detection of a breast cancer biomarker. In this manuscript, we investigate the detection of the Bacillus anthracis protective antigen using antibodies conjugated with polymer-coated quantum dots. Kinetics of binding on the waveguide-based biosensor is reported. We compare the sensitivity of quantum dot labeled antibodies to those labeled with AlexaFluor and demonstrate the photostability of the former in our assay platform. In addition, we compare sulfydryl labeling of the antibody in the hinge region to that of nonspecific amine labeling. This is but the first step in developing a multiplex assay for such biomarkers on our waveguide platform.« less

  19. Multichannel waveguides for the simultaneous detection of disease biomarkers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mukundan, Harshini; Price, Dominique Z; Grace, Wynne K

    2009-01-01

    The sensor team at the Los Alamos National Laboratory has developed a waveguide-based optical biosensor that has previously been used for the detection of biomarkers associated with diseases such as tuberculosis, breast cancer, anthrax and influenza in complex biological samples (e.g., serum and urine). However, no single biomarker can accurately predict disease. To address this issue, we developed a multiplex assay for the detection of components of the Bacillus anthracis lethal toxin on single mode planar optical waveguides with tunable quantum dots as the fluorescence reporter. This limited ability to multiplex is still insufficient for accurate detection of disease ormore » for monitoring prognosis. In this manuscript, we demonstrate for the first time, the design, fabrication and successful evaluation of a multichannel planar optical waveguide for the simultaneous detection of at least three unknown samples in quadruplicate. We demonstrate the simultaneous, rapid (30 min), quantitative (with internal standard) and sensitive (limit of detection of 1 pM) detection of protective antigen and lethal factor of Bacillus anthracis in complex biological samples (serum) using specific monoclonal antibodies labeled with quantum dots as the fluorescence reporter.« less

  20. Photonic crystal-based optical biosensor: a brief investigation

    NASA Astrophysics Data System (ADS)

    Divya, J.; Selvendran, S.; Sivanantha Raja, A.

    2018-06-01

    In this paper, a two-dimensional photonic crystal biosensor for medical applications based on two waveguides and a nanocavity was explored with different shoulder-coupled nanocavity structures. The most important biosensor parameters, like the sensitivity and quality factor, can be significantly improved. By injecting an analyte into a sensing hole, the refractive index of the hole was changed. This refractive index biosensor senses the changes and shifts its operating wavelength accordingly. The transmission characteristics of light in the biosensor under different refractive indices that correspond to the change in the analyte concentration are analyzed by the finite-difference time-domain method. The band gap for each structure is designed and observed by the plane wave expansion method. These proposed structures are designed to obtain an analyte refractive index variation of about 1–1.5 in an optical wavelength range of 1.250–1.640 µm. Accordingly, an improved sensitivity of 136.6 nm RIU‑1 and a quality factor as high as 3915 is achieved. An important feature of this structure is its very small dimensions. Such a combination of attributes makes the designed structure a promising element for label-free biosensing applications.

  1. Flexible Transient Optical Waveguides and Surface-Wave Biosensors Constructed from Monocrystalline Silicon.

    PubMed

    Bai, Wubin; Yang, Hongjun; Ma, Yinji; Chen, Hao; Shin, Jiho; Liu, Yonghao; Yang, Quansan; Kandela, Irawati; Liu, Zhonghe; Kang, Seung-Kyun; Wei, Chen; Haney, Chad R; Brikha, Anlil; Ge, Xiaochen; Feng, Xue; Braun, Paul V; Huang, Yonggang; Zhou, Weidong; Rogers, John A

    2018-06-26

    Optical technologies offer important capabilities in both biological research and clinical care. Recent interest is in implantable devices that provide intimate optical coupling to biological tissues for a finite time period and then undergo full bioresorption into benign products, thereby serving as temporary implants for diagnosis and/or therapy. The results presented here establish a silicon-based, bioresorbable photonic platform that relies on thin filaments of monocrystalline silicon encapsulated by polymers as flexible, transient optical waveguides for accurate light delivery and sensing at targeted sites in biological systems. Comprehensive studies of the mechanical and optical properties associated with bending and unfurling the waveguides from wafer-scale sources of materials establish general guidelines in fabrication and design. Monitoring biochemical species such as glucose and tracking physiological parameters such as oxygen saturation using near-infrared spectroscopic methods demonstrate modes of utility in biomedicine. These concepts provide versatile capabilities in biomedical diagnosis, therapy, deep-tissue imaging, and surgery, and suggest a broad range of opportunities for silicon photonics in bioresorbable technologies. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Photonic crystal waveguide-based biosensor for detection of diseases

    NASA Astrophysics Data System (ADS)

    Chopra, Harshita; Kaler, Rajinder S.; Painam, Balveer

    2016-07-01

    A biosensor is a device that is used to detect the analytes or molecules of a sample by means of a binding mechanism. A two-dimensional photonic crystal waveguide-based biosensor is designed with a diamond-shaped ring resonator and two waveguides: a bus waveguide and a drop waveguide. The sensing mechanism is based on change in refractive index of the analytes, leading to a shift in the peak resonant wavelength. This mechanism can be used in the field of biomedical treatment where different body fluids such as blood, tears, saliva, or urine can be used as the analyte in which different components of the fluid can be detected. It can also be used to differentiate between the cell lines of a normal and an unhealthy human being. Average value of quality factor for this device comes out to be 1082.2063. For different analytes used, the device exhibits enhanced sensitivity and, hence, it is useful for the detection of diseases.

  3. Photonics-on-a-chip: recent advances in integrated waveguides as enabling detection elements for real-world, lab-on-a-chip biosensing applications.

    PubMed

    Washburn, Adam L; Bailey, Ryan C

    2011-01-21

    By leveraging advances in semiconductor microfabrication technologies, chip-integrated optical biosensors are poised to make an impact as scalable and multiplexable bioanalytical measurement tools for lab-on-a-chip applications. In particular, waveguide-based optical sensing technology appears to be exceptionally amenable to chip integration and miniaturization, and, as a result, the recent literature is replete with examples of chip-integrated waveguide sensing platforms developed to address a wide range of contemporary analytical challenges. As an overview of the most recent advances within this dynamic field, this review highlights work from the last 2-3 years in the areas of grating-coupled, interferometric, photonic crystal, and microresonator waveguide sensors. With a focus towards device integration, particular emphasis is placed on demonstrations of biosensing using these technologies within microfluidically controlled environments. In addition, examples of multiplexed detection and sensing within complex matrices--important features for real-world applicability--are given special attention.

  4. A plastic total internal reflection-based photoluminescence device for enzymatic biosensors

    NASA Astrophysics Data System (ADS)

    Thakkar, Ishan G.

    Growing concerns for quality of water, food and beverages in developing and developed countries drive sizeable markets for mass-producible, low cost devices that can measure the concentration of contaminant chemicals in water, food, and beverages rapidly and accurately. Several fiber-optic enzymatic biosensors have been reported for these applications, but they exhibit very strong presence of scattered excitation light in the signal for sensing, requiring expensive thin-film filters, and their non-planar structure makes them challenging to mass-produce. Several other planar optical waveguide-based biosensors prove to be relatively costly and more fragile due to constituent materials and the techniques involved in their fabrication. So, a plastic total internal reflection (TIR)-based low cost, low scatter, field-portable device for enzymatic biosensors is fabricated and demonstrated. The design concept of the TIR-based photoluminescent enzymatic biosensor device is explained. An analysis of economical materials with appropriate optical and chemical properties is presented. PMMA and PDMS are found to be appropriate due to their high chemical resistance, low cost, high optical transmittance and low auto-fluorescence. The techniques and procedures used for device fabrication are discussed. The device incorporated a PMMA-based optical waveguide core and PDMS-based fluid cell with simple multi-mode fiber-optics using cost-effective fabrication techniques like molding and surface modification. Several techniques of robustly depositing photoluminescent dyes on PMMA core surface are discussed. A pH-sensitive fluorescent dye, fluoresceinamine, and an O2-sensitive phosphorescent dye, Ru(dpp) both are successfully deposited using Si-adhesive gel-based as well as HydroThane-based deposition methods. Two different types of pH-sensors using two different techniques of depositing fluoresceinamine are demonstrated. Also, the effect of concentration of fluoresceinamine-dye molecules on fluorescence intensity and scattered excitation light intensity is investigated. The fluorescence intensity to the scattered excitation light intensity ratio for dye deposition is found to increase with increase in concentration. However, both the absolute fluorescence intensity and absolute scatter intensity are found to decrease in different amounts with an increase in concentration. An enzymatic hydrogen peroxide (H2O2) sensor is made and demonstrated by depositing Ruthenium-based phosphorescent dye (Ru(dpp) 3) and catalase-enzyme on the surface of the waveguide core. The O 2-sensitive phosphorescence of Ru(dpp)3 is used as a transduction signal and the catalase-enzyme is used as a bio-component for sensing. The H2O2 sensor exhibits a phosphorescence signal to scattered excitation light ratio of 100+/-18 without filtering. The unfiltered device demonstrates a detection limit of (2.20+/-0.6) microM with the linear range from 200microM to 20mM. An enzymatic lactose sensor is designed and characterized using Si-adhesive gel based Ru(dpp)3 deposition and oxidase enzyme. The lactose sensor exhibits the linear range of up to 0.8mM, which is too small for its application in industrial process control. So, a flow cell-based sensor device with a fluid reservoir is proposed and fabricated to increase the linear range of the sensor. Also, a multi-channel pH-sensor device with four channels is designed and fabricated for simultaneous sensing of multiple analytes.

  5. Biosensors for DNA sequence detection

    NASA Technical Reports Server (NTRS)

    Vercoutere, Wenonah; Akeson, Mark

    2002-01-01

    DNA biosensors are being developed as alternatives to conventional DNA microarrays. These devices couple signal transduction directly to sequence recognition. Some of the most sensitive and functional technologies use fibre optics or electrochemical sensors in combination with DNA hybridization. In a shift from sequence recognition by hybridization, two emerging single-molecule techniques read sequence composition using zero-mode waveguides or electrical impedance in nanoscale pores.

  6. Customization of Protein Single Nanowires for Optical Biosensing.

    PubMed

    Sun, Yun-Lu; Sun, Si-Ming; Wang, Pan; Dong, Wen-Fei; Zhang, Lei; Xu, Bin-Bin; Chen, Qi-Dai; Tong, Li-Min; Sun, Hong-Bo

    2015-06-24

    An all-protein single-nanowire optical biosensor is constructed by a facile and general femtosecond laser direct writing approach with nanoscale structural customization. As-formed protein single nanowires show excellent optical properties (fine waveguiding performance and bio-applicable transmission windows), and are utilized as evanescent optical nanobiosensors for label-free biotin detection. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Waveguide-excited fluorescence microarray

    NASA Astrophysics Data System (ADS)

    Sagarzazu, Gabriel; Bedu, Mélanie; Martinelli, Lucio; Ha, Khoi-Nguyen; Pelletier, Nicolas; Safarov, Viatcheslav I.; Weisbuch, Claude; Gacoin, Thierry; Benisty, Henri

    2008-04-01

    Signal-to-noise ratio is a crucial issue in microarray fluorescence read-out. Several strategies are proposed for its improvement. First, light collection in conventional microarrays scanners is quite limited. It was recently shown that almost full collection can be achieved in an integrated lens-free biosensor, with labelled species hybridizing practically on the surface of a sensitive silicon detector [L. Martinelli et al. Appl. Phys. Lett. 91, 083901 (2007)]. However, even with such an improvement, the ultimate goal of real-time measurements during hybridization is challenging: the detector is dazzled by the large fluorescence of labelled species in the solution. In the present paper we show that this unwanted signal can effectively be reduced if the excitation light is confined in a waveguide. Moreover, the concentration of excitation light in a waveguide results in a huge signal gain. In our experiment we realized a structure consisting of a high index sol-gel waveguide deposited on a low-index substrate. The fluorescent molecules deposited on the surface of the waveguide were excited by the evanescent part of a wave travelling in the guide. The comparison with free-space excitation schemes confirms a huge gain (by several orders of magnitude) in favour of waveguide-based excitation. An optical guide deposited onto an integrated biosensor thus combines both advantages of ideal light collection and enhanced surface localized excitation without compromising the imaging properties. Modelling predicts a negligible penalty from spatial cross-talk in practical applications. We believe that such a system would bring microarrays to hitherto unattained sensitivities.

  8. Simulation of the novel compact structure of an interferometric biosensor based on multimode interference waveguides

    NASA Astrophysics Data System (ADS)

    Xhoxhi, Moisi; Dudia, Alma; Ymeti, Aurel

    2017-05-01

    We propose the novel structure of an interferometric biosensor based on multimode interference (MMI) waveguides. We present the design of the biosensor using eigenmode expansion (EME) method in accordance with the requirements and standards of today's photonic technology. The MMI structures with a 90 nm Si3N4 core are used as power splitters with 5 outputs. The 5 high-resolution images at the end of the multimode region show high power balance. We analyze the coupling efficiency of the laser source with the structure, the excess loss and power imbalance for different compact MMI waveguides with widths ranging from 45 μm to 15 μm. For a laser source with a tolerance of +/-1mm in linearization we could achieve a coupling efficiency of 52%. MMI waveguides with tapered channels show excess loss values under 0.5 dB and power imbalance values under 0.08 dB. In addition, we show that for a 10 nm deviation of the source wavelength from its optimal value and for a 10 μm deviation of the MMI length from its optimal value, the performance of the MMI waveguides remains acceptable. Finally, we analyze the power budget of the whole biosensor structure and show that it is sufficient for the proper operation of this device.

  9. A novel C-shaped, gold nanoparticle coated, embedded polymer waveguide for localized surface plasmon resonance based detection.

    PubMed

    Prabhakar, Amit; Mukherji, Soumyo

    2010-12-21

    In this study, a novel embedded optical waveguide based sensor which utilizes localized surface plasmon resonance of gold nanoparticles coated on a C-shaped polymer waveguide is being reported. The sensor, as designed, can be used as an analysis chip for detection of minor variations in the refractive index of its microenvironment, which makes it suitable for wide scale use as an affinity biosensor. The C-shaped waveguide coupled with microfluidic channel was fabricated by single step patterning of SU8 on an oxidized silicon wafer. The absorbance due to the localized surface plasmon resonance (LSPR) of SU8 waveguide bound gold nano particle (GNP) was found to be linear with refractive index changes between 1.33 and 1.37. A GNP coated C-bent waveguide of 200 μ width with a bend radius of 1 mm gave rise to a sensitivity of ~5 ΔA/RIU at 530 nm as compared to the ~2.5 ΔA/RIU (refractive index units) of the same dimension bare C-bend SU8 waveguide. The resolution of the sensor probe was ~2 × 10(-4) RIU.

  10. Silicon on-chip bandpass filters for the multiplexing of high sensitivity photonic crystal microcavity biosensors

    PubMed Central

    Chakravarty, Swapnajit; Yang, Chun-Ju; Wang, Zheng; Tang, Naimei; Fan, Donglei; Chen, Ray T.

    2015-01-01

    A method for the dense integration of high sensitivity photonic crystal (PC) waveguide based biosensors is proposed and experimentally demonstrated on a silicon platform. By connecting an additional PC waveguide filter to a PC microcavity sensor in series, a transmission passband is created, containing the resonances of the PC microcavity for sensing purpose. With proper engineering of the passband, multiple high sensitivity PC microcavity sensors can be integrated into microarrays and be interrogated simultaneously between a single input and a single output port. The concept was demonstrated with a 2-channel L55 PC biosensor array containing PC waveguide filters. The experiment showed that the sensors on both channels can be monitored simultaneously from a single output spectrum. Less than 3 dB extra loss for the additional PC waveguide filter is observed. PMID:25829549

  11. Silicon on-chip bandpass filters for the multiplexing of high sensitivity photonic crystal microcavity biosensors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yan, Hai, E-mail: hai.yan@utexas.edu; Zou, Yi; Yang, Chun-Ju

    A method for the dense integration of high sensitivity photonic crystal (PC) waveguide based biosensors is proposed and experimentally demonstrated on a silicon platform. By connecting an additional PC waveguide filter to a PC microcavity sensor in series, a transmission passband is created, containing the resonances of the PC microcavity for sensing purpose. With proper engineering of the passband, multiple high sensitivity PC microcavity sensors can be integrated into microarrays and be interrogated simultaneously between a single input and a single output port. The concept was demonstrated with a 2-channel L55 PC biosensor array containing PC waveguide filters. The experimentmore » showed that the sensors on both channels can be monitored simultaneously from a single output spectrum. Less than 3 dB extra loss for the additional PC waveguide filter is observed.« less

  12. Biosensing using long-range surface plasmon waveguides

    NASA Astrophysics Data System (ADS)

    Krupin, Oleksiy; Khodami, Maryam; Fan, Hui; Wong, Wei Ru; Mahamd Adikan, Faisal Rafiq; Berini, Pierre

    2017-05-01

    Long-range surface plasmon waveguides, and their application to various transducer architectures for amplitude- or phase-sensitive biosensing, are discussed. Straight and Y-junction waveguides are used for direct intensity-based detection, whereas Bragg gratings and single-, dual- and triple-output Mach Zehnder interferometers are used for phasebased detection. In either case, multiple-output biosensors which provide means for referencing are very useful to eliminate common perturbations and drift. Application of the biosensors to disease detection in complex fluids is discussed. Application to biomolecular interaction analysis and kinetics extraction is also discussed.

  13. Phase 2 SBIR Final Report: An Ultra-Sensitive Optical Biosensor for Flood Safety

    DTIC Science & Technology

    2002-08-23

    can be completed in 2 to 4 hours. Currently accepted tests using commercial test kits based on immunochemical techniques offer results in 22 to 24...tagging is imperfect, leading to a background of non-specific surface and molecular binding limiting the signal. The use of a reporter fluorochrome can ...Waveguide Patterning: Surface flow channels: The rectangular cuvettes (as shown in Section II, Figure 4-3) can be etched using standard techniques. The

  14. Steering and filtering white light with resonant waveguide gratings

    NASA Astrophysics Data System (ADS)

    Quaranta, Giorgio; Basset, Guillaume; Martin, Olivier J. F.; Gallinet, Benjamin

    2017-08-01

    A novel thin-film single-layer structure based on resonant waveguide gratings (RWGs) allows to engineer selective color filtering and steering of white light. The unit cell of the structure consists of two adjacent finite-length and cross-talking RWGs, where the former acts as in-coupler and the latter acts as out-coupler. The structure is made by only one nano-imprint lithography replication and one thin film layer deposition, making it fully compatible with up-scalable fabrication processes. We characterize a fabricated optical security element designed to work with the flash and the camera of a smartphone in off-axis light steering configuration, where the pattern is revealed only by placing the smartphone in the proper position. Widespread applications are foreseen in a variety of fields, such as multifocal or monochromatic lenses, solar cells, biosensors, security devices and seethrough optical combiners for near-eye displays.

  15. Preparation of Mach-Zehnder interferometric photonic biosensors by inkjet printing technology

    NASA Astrophysics Data System (ADS)

    Strasser, Florian; Melnik, Eva; Muellner, Paul; Jiménez-Meneses, Pilar; Nechvile, Magdalena; Koppitsch, Guenther; Lieberzeit, Peter; Laemmerhofer, Michael; Heer, Rudolf; Hainberger, Rainer

    2017-05-01

    Inkjet printing is a versatile method to apply surface modification procedures in a spatially controlled, cost-effective and mass-fabrication compatible manner. Utilizing this technology, we investigate two different approaches for functionalizing label-free optical waveguide based biosensors: a) surface modification with amine-based functional polymers (biotin-modified polyethylenimine (PEI-B)) employing active ester chemistry and b) modification with dextran based hydrogel thin films employing photoactive benzophenone crosslinker moieties. Whereas the modification with PEI-B ensures high receptor density at the surface, the hydrogel films can serve both as a voluminous matrix binding matrix and as a semipermeable separation layer between the sensor surface and the sample. We use the two surface modification strategies both individually and in combination for binding studies towards the detection of the protein inflammation biomarker, C-reactive protein (CRP). For the specific detection of CRP, we compare two kinds of capture molecules, namely biotinylated antibodies and biotinylated CRP-specific DNA based aptamers. Both kinds of capture molecules were immobilized on the PEI-B by means of streptavidin-biotin affinity binding. As transducer, we use an integrated four-channel silicon nitride (Si3N4) waveguide based Mach-Zehnder interferometric (MZI) photonic sensing platform operating at a wavelength of 850nm (TM-mode).

  16. Hard and flexible optical printed circuit board

    NASA Astrophysics Data System (ADS)

    Lee, El-Hang; Lee, Hyun Sik; Lee, S. G.; O, B. H.; Park, S. G.; Kim, K. H.

    2007-02-01

    We report on the design and fabrication of hard and flexible optical printed circuit boards (O-PCBs). The objective is to realize generic and application-specific O-PCBs, either in hard form or flexible form, that are compact, light-weight, low-energy, high-speed, intelligent, and environmentally friendly, for low-cost and high-volume universal applications. The O-PCBs consist of 2-dimensional planar arrays of micro/nano-scale optical wires, circuits and devices that are interconnected and integrated to perform the functions of sensing, storing, transporting, processing, switching, routing and distributing optical signals on flat modular boards. For fabrication, the polymer and organic optical wires and waveguides are first fabricated on a board and are used to interconnect and integrate micro/nano-scale photonic devices. The micro/nano-optical functional devices include lasers, detectors, switches, sensors, directional couplers, multi-mode interference devices, ring-resonators, photonic crystal devices, plasmonic devices, and quantum devices. For flexible boards, the optical waveguide arrays are fabricated on flexible poly-ethylen terephthalate (PET) substrates by UV embossing. Electrical layer carrying VCSEL and PD array is laminated with the optical layer carrying waveguide arrays. Both hard and flexible electrical lines are replaced with high speed optical interconnection between chips over four waveguide channels up to 10Gbps on each. We discuss uses of hard or flexible O-PCBs for telecommunication systems, computer systems, transportation systems, space/avionic systems, and bio-sensor systems.

  17. Detection of lipopolysaccharides in serum using a waveguide-based optical biosensor

    NASA Astrophysics Data System (ADS)

    Noormohamed, Aneesa; Stromberg, Loreen R.; Anderson, Aaron S.; Karim, Zachary; Dighe, Priya; Kempaiah, Prakasha; Ong'echa, John M.; Perkins, Douglas J.; Doggett, Norman; McMahon, Benjamin; Mukundan, Harshini

    2017-02-01

    Direct ultra-sensitive detection of pathogen biomarkers in blood could provide a universal strategy for diagnosis of bacterial infections, which remain a leading cause of morbidity and mortality in many areas of the world. Many factors complicate diagnosis, including the presence of multiple co-infections in a given patient, and lack of infrastructure in rural settings. In some pediatric patients, such as those in areas with poor resources, an additional challenge exists with low sample volumes due to age and other health factors such as anemia and dehydration. Our team is working on developing novel diagnostic assays, with a waveguide-based biosensor platform, to rapidly and specifically identify pathogen biomarkers from small samples of serum or plasma, allowing for the timely and sensitive diagnosis of infection at the point of care. In addition to the platform, we have developed novel membrane insertion and lipoprotein capture assay methods, to capture lipidated pathogen biomarkers in aqueous blood, by virtue of their interactions with host lipoprotein carriers. Herein, we demonstrate our efforts to adapt the lipoprotein capture assay for the detection of small concentrations of pathogen-secreted lipopolysaccharides in aqueous blood, with the ultimate aim of diagnosing Gram-negative infections effectively.

  18. An optical biosensor for detection of pathogen biomarkers from Shiga toxin-producing Escherichia coli in ground beef samples

    NASA Astrophysics Data System (ADS)

    Lamoureux, Loreen; Adams, Peter; Banisadr, Afsheen; Stromberg, Zachary; Graves, Steven; Montano, Gabriel; Moxley, Rodney; Mukundan, Harshini

    2014-03-01

    Shiga toxin-producing Escherichia coli (STEC) poses a serious threat to human health through the consumption of contaminated food products, particularly beef and produce. Early detection in the food chain, and discrimination from other non-pathogenic Escherichia coli (E. coli), is critical to preventing human outbreaks, and meeting current agricultural screening standards. These pathogens often present in low concentrations in contaminated samples, making discriminatory detection difficult without the use of costly, time-consuming methods (e.g. culture). Using multiple signal transduction schemes (including novel optical methods designed for amphiphiles), specific recognition antibodies, and a waveguide-based optical biosensor developed at Los Alamos National Laboratory, we have developed ultrasensitive detection methods for lipopolysaccharides (LPS), and protein biomarkers (Shiga toxin) of STEC in complex samples (e.g. beef lysates). Waveguides functionalized with phospholipid bilayers were used to pull down amphiphilic LPS, using methods (membrane insertion) developed by our team. The assay format exploits the amphiphilic biochemistry of lipoglycans, and allows for rapid, sensitive detection with a single fluorescent reporter. We have used a combination of biophysical methods (atomic force and fluorescence microscopy) to characterize the interaction of amphiphiles with lipid bilayers, to efficiently design these assays. Sandwich immunoassays were used for detection of protein toxins. Biomarkers were spiked into homogenated ground beef samples to determine performance and limit of detection. Future work will focus on the development of discriminatory antibodies for STEC serotypes, and using quantum dots as the fluorescence reporter to enable multiplex screening of biomarkers.

  19. Chemical, biochemical, and environmental fiber sensors III; Proceedings of the Meeting, Boston, MA, Sept. 4, 5, 1991

    NASA Astrophysics Data System (ADS)

    Lieberman, Robert A.

    Various papers on chemical, biochemical, and environmental fiber sensors are presented. Individual topics addressed include: fiber optic pressure sensor for combustion monitoring and control, viologen-based fiber optic oxygen sensors, renewable-reagent fiber optic sensor for ocean pCO2, transition metal complexes as indicators for a fiber optic oxygen sensor, fiber optic pH measurements using azo indicators, simple reversible fiber optic chemical sensors using solvatochromic dyes, totally integrated optical measuring sensors, integrated optic biosensor for environmental monitoring, radiation dosimetry using planar waveguide sensors, optical and piezoelectric analysis of polymer films for chemical sensor characterization, source polarization effects in an optical fiber fluorosensor, lens-type refractometer for on-line chemical analysis, fiber optic hydrocarbon sensor system, chemical sensors for environmental monitoring, optical fibers for liquid-crystal sensing and logic devices, suitability of single-mode fluoride fibers for evanescent-wave sensing, integrated modules for fiber optic sensors, optoelectronic sensors based on narrowband A3B5 alloys, fiber Bragg grating chemical sensor.

  20. Integrated polymer-based Mach-Zehnder interferometer label-free streptavidin biosensor compatible with injection molding.

    PubMed

    Bruck, R; Melnik, E; Muellner, P; Hainberger, R; Lämmerhofer, M

    2011-05-15

    We report the development of a Mach-Zehnder interferometer biosensor based on a high index contrast polymer material system and the demonstration of label-free online measurement of biotin-streptavidin binding on the sensor surface. The surface of the polyimide waveguide core layer was functionalized with 3-mercaptopropyl trimethoxy silane and malemide tagged biotin. Several concentrations of Chromeon 642-streptavidin dissolved in phosphate buffered saline solution were rinsed over the functionalized sensor surface by means of a fluidic system and the biotin-streptavidin binding process was observed in the output signal of the interferometer at a wavelength of 1310 nm. Despite the large wavelength and the comparatively low surface sensitivity of the sensor system due to the low index contrast in polymer material systems compared to inorganic material systems, we were able to resolve streptavidin concentrations of down to 0.1 μg/ml. The polymer-based optical sensor design is fully compatible with cost-efficient mass production technologies such as injection molding and spin coating, which makes it an attractive alternative to inorganic optical sensors. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. A highly-sensitive label-free biosensor based on two dimensional photonic crystals with negative refraction

    NASA Astrophysics Data System (ADS)

    Malmir, Narges; Fasihi, Kiazand

    2017-11-01

    In this work, we present a novel high-sensitive optical label-free biosensor based on a two-dimensional photonic crystal (2D PC). The suggested structure is composed of a negative refraction structure in a hexagonal lattice PC, along with a positive refraction structure which is arranged in a square lattice PC. The frequency shift of the transmission peak is measured respect to the changes of refractive indices of the studied materials (the blood plasma, water, dry air and normal air). The studied materials are filled into a W1 line-defect waveguide which is located in the PC structure with positive refraction (the microfluidic nanochannel). Our numerical simulations, which are based on finite-difference time-domain (FDTD) method, show that in the proposed structure, a sensitivity about 1100 nm/RIU and a transmission efficiency more than 75% can be achieved. With this design, to the best of our knowledge, the obtained sensitivity and the transmission efficiency are one of the highest values in the reported PC label-free biosensors.

  2. Goos-Hänchen effect in semiconductor metamaterial waveguide and its application as a biosensor

    NASA Astrophysics Data System (ADS)

    Tang, Tingting; Li, Chaoyang; Luo, Li; Zhang, Yanfen; Li, Jie

    2016-06-01

    We investigate Goos-Hänchen (GH) effect in a prism waveguide coupling structure with semiconductor metamaterial (SMM) of ZnGaO/ZnO multilayer and explore the possibility as a biosensor. The GH effect in three different waveguides and their performances as a refractive index sensor to detect glycerol concentration in water are analyzed. The SMM brings a periodic property of GH shift peaks which is not found in other waveguides. It is also verified that setting coupling layer of the prism waveguide coupling structure as sensing area is an effective method to significantly increase the sensitivity to refractive index variation. A schematic diagram for the biosensor configuration is designed, and the sensitivity distribution for different glycerol water index is given. Calculation results show that in the proposed biosensor the maximum sensitivity reaches 3.2 × 106 μm/RIU and resolution reaches 1.6 × 10-7 (around 1.33306) with high sensitive position sensitive detector.

  3. Chemical, biochemical, and environmental fiber sensors IV; Proceedings of the Meeting, Boston, MA, Sept. 8, 9, 1992

    NASA Astrophysics Data System (ADS)

    Lieberman, Robert A.

    Various paper on chemical, biochemical, and environmental fiber sensors are presented. Some of the individual topics addressed include: evanescent-wave fiber optic (FO) biosensor, refractive-index sensors based on coupling to high-index multimode overlays, advanced technique in FO sensors, design of luminescence-based temperature sensors, NIR fluorescence in FO applications, FO sensor based on microencapsulated reagents, emitters and detectors for optical gas and chemical sensing, tunable fiber laser source for methane detection at 1.68 micron, FO fluorometer based on a dual-wavelength laser excitation source, thin polymer films as active components of FO chemical sensors, submicron optical sources for single macromolecule detection, nanometer optical fiber pH sensor. Also discussed are: microfabrication of optical sensor array, luminescent FO sensor for the measurement of pH, time-domain fluorescence methods as applied to pH sensing, characterization of a sol-gel-entrapped artificial receptor, FO technology for nuclear waste cleanup, spectroscopic gas sensing with IR hollow waveguides, dissolved-oxygen quenching of in situ fluorescence measurements.

  4. Integrated optical biosensor system (IOBS)

    DOEpatents

    Grace, Karen M.; Sweet, Martin R.; Goeller, Roy M.; Morrison, Leland Jean; Grace, Wynne Kevin; Kolar, Jerome D.

    2007-10-30

    An optical biosensor has a first enclosure with a pathogen recognition surface, including a planar optical waveguide and grating located in the first enclosure. An aperture is in the first enclosure for insertion of sample to be investigated to a position in close proximity to the pathogen recognition surface. A laser in the first enclosure includes means for aligning and means for modulating the laser, the laser having its light output directed toward said grating. Detection means are located in the first enclosure and in optical communication with the pathogen recognition surface for detecting pathogens after interrogation by the laser light and outputting the detection. Electronic means is located in the first enclosure and receives the detection for processing the detection and outputting information on the detection, and an electrical power supply is located in the first enclosure for supplying power to the laser, the detection means and the electronic means.

  5. Fabrication of polyaniline-HCl cladding modified fiber optic intrinsic biosensor for glucose detection

    NASA Astrophysics Data System (ADS)

    Pahurkar, Vikas; Tamgadge, Yuoraj; Muley, Gajanan

    2016-05-01

    In the present study, we have fabricated and studied response of cladding modified fiber optic intrinsic glucose biosensor (FOIGB). The optical fiber was used as a light transforming waveguide and sensing element fabricated over it by applying a thin layer of polymer. The cladding of the sensor was modified with the polyaniline-hydrochloric acid (PANI-HCl) polymer matrix. The PANI-HCl matrix provides an amorphous morphology useful to immobilize glucose oxidase (GOx) biomolecules through cross-linking technique via glutaraldehyde. The present sensor was used to detect the glucose analyte in the solution. In the sensing response study of FOIGB toward glucose, novel modal power distribution (MPD) technique was used. The reaction between GOx and glucose changes the optical properties of prepared FOIGB and hence modify MPD at output as a function of glucose concentration. The nature and surface morphology of PANI-HCl matrix has been studied.

  6. Light refocusing with up-scalable resonant waveguide gratings in confocal prolate spheroid arrangements

    NASA Astrophysics Data System (ADS)

    Quaranta, Giorgio; Basset, Guillaume; Benes, Zdenek; Martin, Olivier J. F.; Gallinet, Benjamin

    2018-01-01

    Resonant waveguide gratings (RWGs) are thin-film structures, where coupled modes interfere with the diffracted incoming wave and produce strong angular and spectral filtering. The combination of two finite-length and impedance matched RWGs allows the creation of a passive beam steering element, which is compatible with up-scalable fabrication processes. Here, we propose a design method to create large patterns of such elements able to filter, steer, and focus the light from one point source to another. The method is based on ellipsoidal mirrors to choose a system of confocal prolate spheroids where the two focal points are the source point and observation point, respectively. It allows finding the proper orientation and position of each RWG element of the pattern, such that the phase is constructively preserved at the observation point. The design techniques presented here could be implemented in a variety of systems, where large-scale patterns are needed, such as optical security, multifocal or monochromatic lenses, biosensors, and see-through optical combiners for near-eye displays.

  7. Molecular Design of Low-Density Multifunctional Hybrid Materials

    DTIC Science & Technology

    2016-01-01

    properties, but also the synergistic interactions of reactive chemical and simulated solar UV environments with the hybrid film which leads to...applications possible including microelectronic interlayer dielectrics, antireflective coatings for solar cells , optical waveguides, size-selective...membranes, biosensors, micro-fluidic structures, and membranes in fuel cells . A critical aspect for all of these applications is that the hybrids

  8. Design of micro-ring optical sensors and circuits for integration on optical printed circuit boards (O-PCBs)

    NASA Astrophysics Data System (ADS)

    Lee, El-Hang; Lee, Hyun S.; Lee, S. G.; O, B. H.; Park, S. G.; Kim, K. H.

    2007-05-01

    We report on the design of micro-ring resonator optical sensors for integration on what we call optical printed circuit boards (O-PCBs). The objective is to realize application-specific O-PCBs, either on hard board or on flexible board, by integrating micro/nano-scale optical sensors for compact, light-weight, low-energy, high-speed, intelligent, and environmentally friendly processing of information. The O-PCBs consist of two-dimensional planar arrays of micro/nano-scale optical wires, circuits and devices that are interconnected and integrated to perform the functions of sensing and then storing, transporting, processing, switching, routing and distributing optical signals that have been collected by means of sensors. For fabrication, the polymer and organic optical wires and waveguides are first fabricated on a board and are used to interconnect and integrate sensors and other micro/ nano-scale photonic devices. Here, in our study, we focus on the sensors based on the micro-ring structures. We designed bio-sensors using silicon based micro-ring resonator. We investigate the characteristics such as sensitivity and selectivity (or quality factor) of micro-ring resonator for their use in bio-sensing application. We performed simulation studies on the quality factor of micro-ring resonators by varying the radius of the ring resonators and the separation between adjacent waveguides. We introduce the effective coupling coefficient as a realistic value to describe the strength of the coupling in micro-ring resonators.

  9. A portable array biosensor for food safety

    NASA Astrophysics Data System (ADS)

    Golden, Joel P.; Ngundi, Miriam M.; Shriver-Lake, Lisa C.; Taitt, Chris R.; Ligler, Frances S.

    2004-11-01

    An array biosensor developed for simultaneous analysis of multiple samples has been utilized to develop assays for toxins and pathogens in a variety of foods. The biochemical component of the multi-analyte biosensor consists of a patterned array of biological recognition elements immobilized on the surface of a planar waveguide. A fluorescence assay is performed on the patterned surface, yielding an array of fluorescent spots, the locations of which are used to identify what analyte is present. Signal transduction is accomplished by means of a diode laser for fluorescence excitation, optical filters and a CCD camera for image capture. A laptop computer controls the miniaturized fluidics system and image capture. Results for four mycotoxin competition assays in buffer and food samples are presented.

  10. Fabrication of Refractive Index Tunable Polydimethylsiloxane Photonic Crystal for Biosensor Application

    NASA Astrophysics Data System (ADS)

    Raman, Karthik; Murthy, T. R. Srinivasa; Hegde, G. M.

    Photonic crystal based nanostructures are expected to play a significant role in next generation nanophotonic devices. Recent developments in two-dimensional (2D) photonic crystal based devices have created widespread interest as such planar photonic structures are compatible with conventional microelectronic and photonic devices. Various optical components such as waveguides, resonators, modulators and demultiplexers have been designed and fabricated based on 2D photonic crystal geometry. This paper presents the fabrication of refractive index tunable Polydimethylsiloxane (PDMS) polymer based photonic crystals. The advantages of using PDMS are mainly its chemical stability, bio-compatibility and the stack reduces sidewall roughness scattering. The PDMS structure with square lattice was fabricated by using silicon substrate patterned with SU8-2002 resist. The 600 nm period grating of PDMS is then fabricated using Nano-imprinting. In addition, the refractive index of PDMS is modified using certain additive materials. The resulting photonic crystals are suitable for application in photonic integrated circuits and biological applications such as filters, cavities or microlaser waveguides.

  11. Porous silicon platform for optical detection of functionalized magnetic particles biosensing.

    PubMed

    Ko, Pil Ju; Ishikawa, Ryousuke; Sohn, Honglae; Sandhu, Adarsh

    2013-04-01

    The physical properties of porous materials are being exploited for a wide range of applications including optical biosensors, waveguides, gas sensors, micro capacitors, and solar cells. Here, we review the fast, easy and inexpensive electrochemical anodization based fabrication porous silicon (PSi) for optical biosensing using functionalized magnetic particles. Combining magnetically labeled biomolecules with PSi offers a rapid and one-step immunoassay and real-time detection by magnetic manipulation of superparamagnetic beads (SPBs) functionalized with target molecules onto corresponding probe molecules immobilized inside nano-pores of PSi. We first give an introduction to electrochemical and chemical etching procedures used to fabricate a wide range of PSi structures. Next, we describe the basic properties of PSi and underlying optical scattering mechanisms that govern their unique optical properties. Finally, we give examples of our experiments that demonstrate the potential of combining PSi and magnetic beads for real-time point of care diagnostics.

  12. System-level integration of active silicon photonic biosensors

    NASA Astrophysics Data System (ADS)

    Laplatine, L.; Al'Mrayat, O.; Luan, E.; Fang, C.; Rezaiezadeh, S.; Ratner, D. M.; Cheung, K.; Dattner, Y.; Chrostowski, L.

    2017-02-01

    Biosensors based on silicon photonic integrated circuits have attracted a growing interest in recent years. The use of sub-micron silicon waveguides to propagate near-infrared light allows for the drastic reduction of the optical system size, while increasing its complexity and sensitivity. Using silicon as the propagating medium also leverages the fabrication capabilities of CMOS foundries, which offer low-cost mass production. Researchers have deeply investigated photonic sensor devices, such as ring resonators, interferometers and photonic crystals, but the practical integration of silicon photonic biochips as part of a complete system has received less attention. Herein, we present a practical system-level architecture which can be employed to integrate the aforementioned photonic biosensors. We describe a system based on 1 mm2 dies that integrate germanium photodetectors and a single light coupling device. The die are embedded into a 16x16 mm2 epoxy package to enable microfluidic and electrical integration. First, we demonstrate a simple process to mimic Fan-Out Wafer-level-Packaging, which enables low-cost mass production. We then characterize the photodetectors in the photovoltaic mode, which exhibit high sensitivity at low optical power. Finally, we present a new grating coupler concept to relax the lateral alignment tolerance down to +/- 50 μm at 1-dB (80%) power penalty, which should permit non-experts to use the biochips in a"plug-and-play" style. The system-level integration demonstrated in this study paves the way towards the mass production of low-cost and highly sensitive biosensors, and can facilitate their wide adoption for biomedical and agro-environmental applications.

  13. Biosensor for detection of dissolved chromium in potable water: A review.

    PubMed

    Biswas, Puja; Karn, Abhinav Kumar; Balasubramanian, P; Kale, Paresh G

    2017-08-15

    The unprecedented deterioration rate of the environmental quality due to rapid urbanization and industrialization causes a severe global health concern to both ecosystem and humanity. Heavy metals are ubiquitous in nature and being used extensively in industrial processes, the exposure to excessive levels could alter the biochemical cycles of living systems. Hence the environmental monitoring through rapid and specific detection of heavy metal contamination in potable water is of paramount importance. Various standard analytical techniques and sensors are used for the detection of heavy metals include spectroscopy and chromatographic methods along with electrochemical, optical waveguide and polymer based sensors. However, the mentioned techniques lack the point of care application as it demands huge capital cost as well as the attention of expert personnel for sample preparation and operation. Recent advancements in the synergetic interaction among biotechnology and microelectronics have advocated the biosensor technology for a wide array of applications due to its characteristic features of sensitivity and selectivity. This review paper has outlined the overview of chromium toxicity, conventional analytical techniques along with a particular emphasis on electrochemical based biosensors for chromium detection in potable water. This article emphasized porous silicon as a host material for enzyme immobilization and elaborated the working principle, mechanism, kinetics of an enzyme-based biosensor for chromium detection. The significant characteristics such as pore size, thickness, and porosity make the porous silicon suitable for enzyme entrapment. Further, several schemes on porous silicon-based immobilized enzyme biosensors for the detection of chromium in potable water are proposed. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Multi-Channel Hyperspectral Fluorescence Detection Excited by Coupled Plasmon-Waveguide Resonance

    PubMed Central

    Du, Chan; Liu, Le; Zhang, Lin; Guo, Jun; Guo, Jihua; Ma, Hui; He, Yonghong

    2013-01-01

    We propose in this paper a biosensor scheme based on coupled plasmon-waveguide resonance (CPWR) excited fluorescence spectroscopy. A symmetrical structure that offers higher surface electric field strengths, longer surface propagation lengths and depths is developed to support guided waveguide modes for the efficient excitation of fluorescence. The optimal parameters for the sensor films are theoretically and experimentally investigated, leading to a detection limit of 0.1 nM (for a Cy5 solution). Multiplex analysis possible with the fluorescence detection is further advanced by employing the hyperspectral fluorescence technique to record the full spectra for every pixel on the sample plane. We demonstrate experimentally that highly overlapping fluorescence (Cy5 and Dylight680) can be distinguished and ratios of different emission sources can be determined accurately. This biosensor shows great potential for multiplex detections of fluorescence analytes. PMID:24129023

  15. Optical biosensors for cell adhesion.

    PubMed

    Ramsden, Jeremy J; Horvath, Robert

    2009-01-01

    Planar optical waveguides offer an ideal substratum for cells on which to reside. The materials from which the waveguides are made--high refractive index transparent dielectrics--correspond to the coatings of medical implants (e.g., the oxides of niobium, tantalum, and titanium) or the high molecular weight polymers used for culture flasks (e.g., polystyrene). The waveguides can furthermore be modified both chemically and morphologically while retaining their full capability for generating an evanescent optical field that has its greatest strength at the interface between the solid substratum and the liquid phase with which it is invariably in contact (i.e., the culture medium bathing the cells), decaying exponentially perpendicular to the interface at a rate controllable by varying the material parameters of the waveguide. Analysis of the perturbation of the evanescent field by the presence of living cells within it enables their size, number density, shape, refractive index (linked to their constitution) and so forth to be determined, the number of parameters depending on the number of waveguide lightmodes analyzed. No labeling of any kind is necessary, and convenient measurement setups are fully compatible with maintaining the cells in their usual environment. If the temporal evolution of the perturbation is analyzed, even more information can be obtained, such as the amount of material (microexudate) secreted by the cell while residing on the surface. Separation of parallel effects simultaneously contributing to the perturbation of the evanescent field can be accomplished by analysis of coupling peak shape when a grating coupler is used to measure the propagation constants of the waveguide lightmodes.

  16. Design, Fabrication, and Packaging of Mach-Zehnder Interferometers for Biological Sensing Applications

    NASA Astrophysics Data System (ADS)

    Novak, Joseph

    Optical biological sensors are widely used in the fields of medical testing, water treatment and safety, gene identification, and many others due to advances in nanofabrication technology. This work focuses on the design of fiber-coupled Mach-Zehnder Interferometer (MZI) based biosensors fabricated on silicon-on-insulator (SOI) wafer. Silicon waveguide sensors are designed with multimode and single-mode dimensions. Input coupling efficiency is investigated by design of various taper structures. Integration processing and packaging is performed for fiber attachment and enhancement of input coupling efficiency. Optical guided-wave sensors rely on single-mode operation to extract an induced phase-shift from the output signal. A silicon waveguide MZI sensor designed and fabricated for both multimode and single-mode dimensions. Sensitivity of the sensors is analyzed for waveguide dimensions and materials. An s-bend structure is designed for the multimode waveguide to eliminate higher-order mode power as an alternative to single-mode confinement. Single-mode confinement is experimentally demonstrated through near field imaging of waveguide output. Y-junctions are designed for 3dB power splitting to the MZI arms and for power recombination after sensing to utilize the interferometric function of the MZI. Ultra-short 10microm taper structures with curved geometries are designed to improve insertion loss from fiber-to-chip without significantly increasing device area and show potential for applications requiring misalignment tolerance. An novel v-groove process is developed for self-aligned integration of fiber grooves for attachment to sensor chips. Thermal oxidation at temperatures from 1050-1150°C during groove processing creates an SiO2 layer on the waveguide end facet to protect the waveguide facet during integration etch processing without additional e-beam lithography processing. Experimental results show improvement of insertion loss compared to dicing preparation and Focused Ion Beam methods using the thermal oxidation process.

  17. Surface desensitization of polarimetric waveguide interferometers

    NASA Astrophysics Data System (ADS)

    Worth, Colin

    Non-specific binding of small molecules to the surface of waveguide biosensors presents a major obstacle to surface-sensing techniques that attempt to detect very low concentrations (<1 g/mm2) of large (500 nm to 3 mum) biological objects. Interferometric waveguide biosensors use the interaction of an evanescent light field outside of the guiding layer with a biological sample to detect a particular type of cell or bacteria at some distance from the sensor surface. In such experiments, binding of small proteins close to the surface can be a significant source of noise. It is possible to significantly improve the signal-to-noise ratio by varying the properties of the biosensor, in order to reduce or eliminate the biosensor's response to a thin protein layer at the waveguide surface, without significantly reducing the response to larger target particles. In many biosensing applications, specifically bound particles, such as bacteria, are much larger than non-specifically bound particles such as proteins. In addition, due to laminar flow conditions at the sensor surface, the latter smaller particles tend to accumulate on the sensor surface. By varying the waveguide parameters, it is possible to vary the sensitivity of the detector response as a function of sample distance from the detector, by changing the properties of the TE0 and TM0 guided modes. This results in a signal reduction of more than 85%, for thin (30 nm or less) layers adjacent to the waveguide surface.

  18. Lab-on-a-Chip Pathogen Sensors for Food Safety

    PubMed Central

    Yoon, Jeong-Yeol; Kim, Bumsang

    2012-01-01

    There have been a number of cases of foodborne illness among humans that are caused by pathogens such as Escherichia coli O157:H7, Salmonella typhimurium, etc. The current practices to detect such pathogenic agents are cell culturing, immunoassays, or polymerase chain reactions (PCRs). These methods are essentially laboratory-based methods that are not at all real-time and thus unavailable for early-monitoring of such pathogens. They are also very difficult to implement in the field. Lab-on-a-chip biosensors, however, have a strong potential to be used in the field since they can be miniaturized and automated; they are also potentially fast and very sensitive. These lab-on-a-chip biosensors can detect pathogens in farms, packaging/processing facilities, delivery/distribution systems, and at the consumer level. There are still several issues to be resolved before applying these lab-on-a-chip sensors to field applications, including the pre-treatment of a sample, proper storage of reagents, full integration into a battery-powered system, and demonstration of very high sensitivity, which are addressed in this review article. Several different types of lab-on-a-chip biosensors, including immunoassay- and PCR-based, have been developed and tested for detecting foodborne pathogens. Their assay performance, including detection limit and assay time, are also summarized. Finally, the use of optical fibers or optical waveguide is discussed as a means to improve the portability and sensitivity of lab-on-a-chip pathogen sensors. PMID:23112625

  19. Integrated optical refractometer based on bend waveguide with air trench structure

    NASA Astrophysics Data System (ADS)

    Ryu, Jin Hwa; Park, Jaehoon; Kang, Chan-mo; Son, Youngdal; Do, Lee-Mi; Baek, Kyu-Ha

    2015-07-01

    This study proposed a novel optical sensor based on a refractometer integrating a bend waveguide and a trench structure. The optical sensor is a planar lightwave circuit (PLC) device involving a bend waveguide with maximum optical loss. A trench structure was aligned with the partially exposed core layer's sidewall of the bend waveguide, providing a quantitative measurement condition. The insertion losses of the proposed 1 x 2 single-mode optical splitter-type sensor were 4.38 dB and 8.67 dB for the reference waveguide and sensing waveguide, respectively, at a wavelength of 1,550 nm. The optical loss of the sensing waveguide depends on the change in the refractive index of the material in contact with the trench, but the reference waveguide had stable optical propagating characteristic regardless of the variations of the refractive index.

  20. Optical transduction of E. Coli O157:H7 concentration by using the enhanced Goos-Hänchen shift

    NASA Astrophysics Data System (ADS)

    Sun, Jingjing; Wang, Xianping; Yin, Cheng; Xiao, Pingping; Li, Honggen; Cao, Zhuangqi

    2012-10-01

    Within the symmetrical metal-cladding waveguide structure, the optical transduction of the E. coli O157:H7 concentration by using the enhanced Goos-Hänchen (GH) shift is demonstrated to be an advantageous alternative over those evanescent wave-based biosensors. The experimental results indicate that the interaction between the analyte and the excited ultrahigh order modes (in the form of the oscillating wave) is the dominant reason leading to ultrahigh sensitivity. On the condition that the intrinsic damping is well-matched with the radiative damping, the giant GH shift (hundreds of micrometers) offers a higher sensitivity than the regular measurement of reflected light intensity. The transduction limit of E. Coli O157:H7 concentration about 100 cfu ml-1 is achieved.

  1. FIBER AND INTEGRATED OPTICS: New type of heterogeneous nanophotonic silicon-on-insulator optical waveguides

    NASA Astrophysics Data System (ADS)

    Tsarev, Andrei V.

    2007-08-01

    A new type of optical waveguides in silicon-on-insulator nanostructures is proposed and studied. Their optical properties are simulated by the beam propagation method and discussed. A new design in the form of heterogeneous waveguide structures is based on the production of additionally heavily doped p+-regions on the sides of a multimode stripe waveguide (the silicon core cross section is ~200 nm × 16 μm). Such doping provides the 'single-mode' behaviour of the heterogeneous waveguide due to the decrease in the optical losses for the fundamental mode and increase in losses for higher-order modes. Single-mode heterogeneous waveguides can be used as base waveguides in photonic and integrated optical elements.

  2. Label-free bimodal waveguide immunosensor for rapid diagnosis of bacterial infections in cirrhotic patients.

    PubMed

    Maldonado, Jesús; González-Guerrero, Ana Belén; Domínguez, Carlos; Lechuga, Laura M

    2016-11-15

    Spontaneous bacterial peritonitis is an acute bacterial infection of ascitic fluid; it has a high incidence in cirrhotic patients and it is associated with high mortality. In such a situation, early diagnosis and treatment is crucial for the survival of the patient. However, bacterial analysis in ascitic fluid is currently based on culture methods, which are time-consuming and laborious. We report here the application of a photonic interferometer biosensor based on a bimodal waveguide (BiMW) for the rapid and label-free detection of bacteria directly in ascitic fluid. The device consists of a straight waveguide in which two modes of the same polarization interfere while interacting with the external medium through their evanescent fields. A bimolecular event occurring on the sensor area of the device (e.g. capturing bacteria) will differently affect each light mode, inducing a variation in the phase of the light exiting at the output of the waveguide. In this work, we demonstrate the quantitative detection of Bacillus cereus in buffer medium and Escherichia coli in undiluted ascitic fluid from cirrhotic patients. In the case of Bacillus cereus detection, the device was able to specifically detect bacteria at relevant concentrations in 12.5min and in the case of Escherichia coli detection, the analysis time was 25min. Extrapolation of the data demonstrated that the detection limits of the biosensor could reach few bacteria per milliliter. Based on the results obtained, we consider that the BiMW biosensor is positioned as a promising new clinical tool for user-friendly, cost-effective and real-time microbiological analysis. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Optical biosensors.

    PubMed

    Damborský, Pavel; Švitel, Juraj; Katrlík, Jaroslav

    2016-06-30

    Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and localized SPR. In addition, other optical biosensor systems are described, such as evanescent wave fluorescence and bioluminescent optical fibre biosensors, as well as interferometric, ellipsometric and reflectometric interference spectroscopy and surface-enhanced Raman scattering biosensors. The optical biosensors discussed here allow the sensitive and selective detection of a wide range of analytes including viruses, toxins, drugs, antibodies, tumour biomarkers and tumour cells. © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  4. 1-D grating based SPR biosensor for the detection of lung cancer biomarkers using Vroman effect

    NASA Astrophysics Data System (ADS)

    Teotia, Pradeep Kumar; Kaler, R. S.

    2018-01-01

    Grating based surface plasmon resonance waveguide biosensor have been reported for the detection of lung cancer biomarkers using Vroman effect. The proposed grating based multilayered biosensor is designed with high detection accuracy for Epidermal growth factor receptor (EGFR) and also analysed to show high detection accuracy with acceptable sensitivity for both cancer biomarkers. The introduction of periodic grating with multilayer metals generates a good resonance that make it possible for early detection of cancerous cells. Using finite difference time domain method, it is observed wavelength of biosensor get red-shifted on variations of the refractive index due to the presence of both the cancerous bio-markers. The reported detection accuracy and sensitivity of proposed biosensor is quite acceptable for both lung cancer biomarkers i.e. Carcinoembryonic antigen (CEA) and Epidermal growth factor receptor (EGFR) which further offer us label free early detection of lung cancer using these biomarkers.

  5. Micro-resonators based on integrated polymer technology for optical sensing

    NASA Astrophysics Data System (ADS)

    Girault, Pauline; Lemaitre, Jonathan; Guendouz, Mohammed; Lorrain, Nathalie; Poffo, Luiz; Gadonna, Michel; Bosc, Dominique

    2014-05-01

    Research on sensors has experienced a noticeable development over the last decades especially in label free optical biosensors. However, compact sensors without markers for rapid, reliable and inexpensive detection of various substances induce a significant research of new technological solutions. The context of this work is the development of a sensor based on easily integrated and inexpensive micro-resonator (MR) component in integrated optics, highly sensitive and selective mainly in the areas of health and food. In this work, we take advantage of our previous studies on filters based on micro-resonators (MR) to experiment a new couple of polymers in the objective to use MR as a sensing function. MRs have been fabricated by processing SU8 polymer as core and PMATRIFE polymer as cladding layer of the waveguide. The refractive index contrast reaches 0.16 @ 1550 nm. Sub-micronic ring waveguides gaps from 0.5 to 1 μm have been successfully achieved with UV (i-line) photolithography. This work confirms our forecasts, published earlier, about the resolution that can be achieved. First results show a good extinction coefficient of ~17 dB, a quality factor around 104 and a finesse of 12. These results are in concordance with the theoretical study and they allow us to validate our technology with this couple of polymers. Work is going on with others lower cladding materials that will be used to further increase refractive index contrast for sensing applications.

  6. Optimization of silicon oxynitrides by plasma-enhanced chemical vapor deposition for an interferometric biosensor

    NASA Astrophysics Data System (ADS)

    Choo, Sung Joong; Lee, Byung-Chul; Lee, Sang-Myung; Park, Jung Ho; Shin, Hyun-Joon

    2009-09-01

    In this paper, silicon oxynitride layers deposited with different plasma-enhanced chemical vapor deposition (PECVD) conditions were fabricated and optimized, in order to make an interferometric sensor for detecting biochemical reactions. For the optimization of PECVD silicon oxynitride layers, the influence of the N2O/SiH4 gas flow ratio was investigated. RF power in the PEVCD process was also adjusted under the optimized N2O/SiH4 gas flow ratio. The optimized silicon oxynitride layer was deposited with 15 W in chamber under 25/150 sccm of N2O/SiH4 gas flow rates. The clad layer was deposited with 20 W in chamber under 400/150 sccm of N2O/SiH4 gas flow condition. An integrated Mach-Zehnder interferometric biosensor based on optical waveguide technology was fabricated under the optimized PECVD conditions. The adsorption reaction between bovine serum albumin (BSA) and the silicon oxynitride surface was performed and verified with this device.

  7. Extraction film for optical waveguide and method of producing same

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tarsa, Eric J.; Durkee, John W.

    2017-05-16

    An optical waveguide includes a waveguide body and a film disposed on a surface of the waveguide body. The film includes a base and a plurality of undercut light extraction elements disposed between the base and the surface.

  8. Real-time label-free biosensing with integrated planar waveguide ring resonators

    NASA Astrophysics Data System (ADS)

    Sohlström, Hans; Gylfason, Kristinn B.; Hill, Daniel

    2010-05-01

    We review the use of planar integrated optical waveguide ring resonators for label free bio-sensing and present recent results from two European biosensor collaborations: SABIO and InTopSens. Planar waveguide ring resonators are attractive for label-free biosensing due to their small footprint, high Q-factors, and compatibility with on-chip optics and microfluidics. This enables integrated sensor arrays for compact labs-on-chip. One application of label-free sensor arrays is for point-of-care medical diagnostics. Bringing such powerful tools to the single medical practitioner is an important step towards personalized medicine, but requires addressing a number of issues: improving limit of detection, managing the influence of temperature, parallelization of the measurement for higher throughput and on-chip referencing, efficient light-coupling strategies to simplify alignment, and packaging of the optical chip and integration with microfluidics. From the SABIO project we report refractive index measurement and label-free biosensing in an 8-channel slotwaveguide ring resonator sensor array, within a compact cartridge with integrated microfluidics. The sensors show a volume sensing detection limit of 5 x 10-6 RIU and a surface sensing detection limit of 0.9 pg/mm2. From the InTopSens project we report early results on silicon-on-insulator racetrack resonators.

  9. Graphene-Based Optical Biosensors and Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tang, Zhiwen; He, Shijiang; Pei, Hao

    2014-01-13

    This chapter focuses on the design, fabrication and application of graphene based optical nanobiosensors. The emerging graphene based optical nanobiosensors demonstrated the promising bioassay and biomedical applications thanking to the unique optical features of graphene. According to the different applications, the graphene can be tailored to form either fluorescent emitter or efficient fluorescence quencher. The exceptional electronic feature of graphene makes it a powerful platform for fabricating the SPR and SERS biosensors. Today the graphene based optical biosensors have been constructed to detect various targets including ions, small biomolecules, DNA/RNA and proteins. This chapter reviews the recent progress in graphene-basedmore » optical biosensors and discusses the opportunities and challenges in this field.« less

  10. Polymer waveguide grating sensor integrated with a thin-film photodetector

    PubMed Central

    Song, Fuchuan; Xiao, Jing; Xie, Antonio Jou; Seo, Sang-Woo

    2014-01-01

    This paper presents a planar waveguide grating sensor integrated with a photodetector (PD) for on-chip optical sensing systems which are suitable for diagnostics in the field and in-situ measurements. III–V semiconductor-based thin-film PD is integrated with a polymer based waveguide grating device on a silicon platform. The fabricated optical sensor successfully discriminates optical spectral characteristics of the polymer waveguide grating from the on-chip PD. In addition, its potential use as a refractive index sensor is demonstrated. Based on a planar waveguide structure, the demonstrated sensor chip may incorporate multiple grating waveguide sensing regions with their own optical detection PDs. In addition, the demonstrated processing is based on a post-integration process which is compatible with silicon complementary metal-oxide semiconductor (CMOS) electronics. Potentially, this leads a compact, chip-scale optical sensing system which can monitor multiple physical parameters simultaneously without need for external signal processing. PMID:24466407

  11. Acrylic and metal based Y-branch plastic optical fiber splitter with optical NOA63 polymer waveguide taper region

    NASA Astrophysics Data System (ADS)

    Ehsan, Abang Annuar; Shaari, Sahbudin; Rahman, Mohd Kamil Abd.

    2011-01-01

    We proposed a simple low-cost acrylic and metal-based Y-branch plastic optical fiber (POF) splitter which utilizes a low cost optical polymer glue NOA63 as the main waveguiding medium at the waveguide taper region. The device is composed of three sections: an input POF waveguide, a middle waveguide taper region and output POF waveguides. A desktop high speed CNC engraver is utilized to produce the mold inserts used for the optical devices. Short POF fibers are inserted into the engraved slots at the input and output ports. UV curable optical polymer glue NOA63 is injected into the waveguide taper region and cured. The assembling is completed when the top plate is positioned to enclose the device structure and connecting screws are secured. Both POF splitters have an average insertion loss of 7.8 dB, coupling ratio of 55: 45 and 57: 43 for the acrylic and metal-based splitters respectively. The devices have excess loss of 4.82 and 4.73 dB for the acrylic and metal-based splitters respectively.

  12. FIBER AND INTEGRATED OPTICS: Waveguide characteristics of real optical strip waveguides

    NASA Astrophysics Data System (ADS)

    Shmal'ko, A. V.; Frolov, V. V.

    1990-01-01

    A study is reported of the influence of the parameters of real thin-film optical strip waveguides on their waveguide characteristics (propagation constants, localization of the mode field, etc.) allowing for the presence of transition layers in a transverse cross section of the base planar waveguide, for the real geometry of this section (which is nearly trapezoidal), and for the thickness of the guiding strip. Analytic expressions are obtained for the optical confinement coefficient and the effective mode format of a weakly guiding symmetric strip waveguide. It is shown that the coefficient representing the fundamental E11x(y) mode is practically independent of the relative thickness t /h (h is the thickness of the base planar waveguide) of the guiding strip provided t /h>=0.5. The corrections to the normalized effective refractive indices of the base planar and strip waveguides are found in order to allow for the real geometry and for the refractive index profile in the strip waveguide.

  13. Design and simulation of MEMS microvalves for silicon photonic biosensor chip

    NASA Astrophysics Data System (ADS)

    Amemiya, Yoshiteru; Nakashima, Yuuto; Maeda, Jun; Yokoyama, Shin

    2018-04-01

    For the early and easy diagnosis of diseases, we have proposed a silicon photonic biosensor chip with two kinds of MEMS microvalves for a multiple-item detection system. The driving voltage of the vertical type with the circular-plate capacitor structure and that of the lateral type with the comb-shaped electrode are investigated. From mechanical calculations, the driving voltage of the vertical type is estimated to be 30 V and that of the lateral type to be 15 V. The propagation loss at the intersecting waveguides of arrayed ring-resonator biosensors is also estimated. In the case of optimized intersecting waveguides, more than 67% transmittance of TE-mode light is simulated for the series connection of 20 intersecting waveguides. It is confirmed that it is possible to fabricate an 8 × 12 arrayed biosensor chip in an area of 1 × 1.5 mm2 taking the device size of the microvalves into consideration. We have, for the first time, designed a whole system, including sensors and a fluid channel with MEMS microvalves.

  14. Microfluidic resonant waveguide grating biosensor system for whole cell sensing

    NASA Astrophysics Data System (ADS)

    Zaytseva, Natalya; Miller, William; Goral, Vasily; Hepburn, Jerry; Fang, Ye

    2011-04-01

    We report on a fluidic resonant waveguide grating (RWG) biosensor system that enables medium throughput measurements of cellular responses under microfluidics in a 32-well format. Dynamic mass redistribution assays under microfluidics differentiate the cross-desensitization process between the β2-adrenoceptor agonist epinephrine and the adenylate cyclase activator forskolin mediated signaling. This system opens new possibility to study cellular processes that are otherwise difficult to achieve using conventional RWG configurations.

  15. Towards an integrated optofluidic system for highly sensitive detection of antibiotics in seawater incorporating bimodal waveguide photonic biosensors and complex, active microfluidics

    NASA Astrophysics Data System (ADS)

    Szydzik, C.; Gavela, A. F.; Roccisano, J.; Herranz de Andrés, S.; Mitchell, A.; Lechuga, L. M.

    2016-12-01

    We present recent results on the realisation and demonstration of an integrated optofluidic lab-on-a-chip measurement system. The system consists of an integrated on-chip automated microfluidic fluid handling subsystem, coupled with bimodal nano-interferometer waveguide technology, and is applied in the context of detection of antibiotics in seawater. The bimodal waveguide (BMWG) is a highly sensitive label-free biosensor. Integration of complex microfluidic systems with bimodal waveguide technology enables on-chip sample handling and fluid processing capabilities and allows for significant automation of experimental processes. The on-chip fluid-handling subsystem is realised through the integration of pneumatically actuated elastomer pumps and valves, enabling high temporal resolution sample and reagent delivery and facilitating multiplexed detection processes.

  16. Magneto-optical non-reciprocal devices in silicon photonics

    PubMed Central

    Shoji, Yuya; Mizumoto, Tetsuya

    2014-01-01

    Silicon waveguide optical non-reciprocal devices based on the magneto-optical effect are reviewed. The non-reciprocal phase shift caused by the first-order magneto-optical effect is effective in realizing optical non-reciprocal devices in silicon waveguide platforms. In a silicon-on-insulator waveguide, the low refractive index of the buried oxide layer enhances the magneto-optical phase shift, which reduces the device footprints. A surface activated direct bonding technique was developed to integrate a magneto-optical garnet crystal on the silicon waveguides. A silicon waveguide optical isolator based on the magneto-optical phase shift was demonstrated with an optical isolation of 30 dB and insertion loss of 13 dB at a wavelength of 1548 nm. Furthermore, a four port optical circulator was demonstrated with maximum isolations of 15.3 and 9.3 dB in cross and bar ports, respectively, at a wavelength of 1531 nm. PMID:27877640

  17. Optical fiber-based biosensors.

    PubMed

    Monk, David J; Walt, David R

    2004-08-01

    This review outlines optical fiber-based biosensor research from January 2001 through September 2003 and was written to complement the previous review in this journal by Marazuela and Moreno-Bondi. Optical fiber-based biosensors combine the use of a biological recognition element with an optical fiber or optical fiber bundle. They are classified by the nature of the biological recognition element used for sensing: enzyme, antibody/antigen (immunoassay), nucleic acid, whole cell, and biomimetic, and may be used for a variety of analytes ranging from metals and chemicals to physiological materials.

  18. Development of a diamond waveguide sensor for sensitive protein analysis using IR quantum cascade lasers

    NASA Astrophysics Data System (ADS)

    Piron, P.; Vargas Catalan, E.; Haas, J.; Österlund, L.; Nikolajeff, F.; Andersson, P. O.; Bergström, J.; Mizaikoff, B.; Karlsson, M.

    2018-02-01

    Microfabricated diamond waveguides, between 5 and 20 μm thick, manufactured by chemical vapor deposition of diamond, followed by standard lithographic techniques and inductively coupled plasma etching of diamond, are used as bio-chemical sensors in the mid infrared domain: 5-11 μm. Infrared light, emitted from a broadly tunable quantum cascade laser with a wavelength resolution smaller than 20 nm, is coupled through the diamond waveguides for attenuated total reflection spectroscopy. The expected advantages of these waveguides are a high sensitivity due to the high number of internal reflections along the propagation direction, a high transmittance in the mid-IR domain, the bio-compatibility of diamond and the possibility of functionalizing the surface layer. The sensor will be used for analyzing different forms of proteins such as α-synuclein which is relevant in understanding the mechanism behind Parkinson's disease. The fabrication process of the waveguide, its characteristics and several geometries are introduced. The optical setup of the biosensor is described and our first measurements on two analytes to demonstrate the principle of the sensing method will be presented. Future use of this sensor includes the functionalization of the diamond waveguide sensor surface to be able to fish out alpha-synuclein from cerebrospinal fluid.

  19. Wavelength selective switch array employing silica-based waveguide frontend with integrated polarization diversity optics.

    PubMed

    Sakamaki, Yohei; Shikama, Kota; Ikuma, Yuichiro; Suzuki, Kenya

    2017-08-21

    We propose a waveguide frontend with integrated polarization diversity optics for a wavelength selective switch (WSS) array with a liquid crystal on silicon switching engine to simplify the free space optics configuration and the alignment process in optical modules. The polarization diversity function is realized by the integration of a waveguide-type polarization beam splitter and a polarization rotating half-wave plate in a beam launcher using silica-based planar lightwave circuit technology. We confirmed experimentally the feasibility of using our proposed waveguide frontend in a two-in-one 1 × 20 WSS. The experimental results show that the fabricated waveguide frontend provides a polarization diversity function without any degradation in optical performance.

  20. Co-integrating plasmonics with Si3N4 photonics towards a generic CMOS compatible PIC platform for high-sensitivity multi-channel biosensors: the H2020 PlasmoFab approach (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Tsiokos, Dimitris M.; Dabos, George; Ketzaki, Dimitra; Weeber, Jean-Claude; Markey, Laurent; Dereux, Alain; Giesecke, Anna Lena; Porschatis, Caroline; Chmielak, Bartos; Wahlbrink, Thorsten; Rochracher, Karl; Pleros, Nikos

    2017-05-01

    Silicon photonics meet most fabrication requirements of standard CMOS process lines encompassing the photonics-electronics consolidation vision. Despite this remarkable progress, further miniaturization of PICs for common integration with electronics and for increasing PIC functional density is bounded by the inherent diffraction limit of light imposed by optical waveguides. Instead, Surface Plasmon Polariton (SPP) waveguides can guide light at sub-wavelength scales at the metal surface providing unique light-matter interaction properties, exploiting at the same time their metallic nature to naturally integrate with electronics in high-performance ASPICs. In this article, we demonstrate the main goals of the recently introduced H2020 project PlasmoFab towards addressing the ever increasing needs for low energy, small size and high performance mass manufactured PICs by developing a revolutionary yet CMOS-compatible fabrication platform for seamless co-integration of plasmonics with photonic and supporting electronic. We demonstrate recent advances on the hosting SiN photonic hosting platform reporting on low-loss passive SiN waveguide and Grating Coupler circuits for both the TM and TE polarization states. We also present experimental results of plasmonic gold thin-film and hybrid slot waveguide configurations that can allow for high-sensitivity sensing, providing also the ongoing activities towards replacing gold with Cu, Al or TiN metal in order to yield the same functionality over a CMOS metallic structure. Finally, the first experimental results on the co-integrated SiN+plasmonic platform are demonstrated, concluding to an initial theoretical performance analysis of the CMOS plasmo-photonic biosensor that has the potential to allow for sensitivities beyond 150000nm/RIU.

  1. Deoxyribonucleic acid (DNA)-based optical materials

    NASA Astrophysics Data System (ADS)

    Grote, James G.; Heckman, Emily M.; Hagen, Joshua A.; Yaney, Perry P.; Subramanyam, Guru; Clarson, Stephen J.; Diggs, Darnell E.; Nelson, Robert L.; Zetts, John S.; Hopkins, F. Kenneth; Ogata, Naoya

    2004-12-01

    Optical materials for waveguiding applications must possess the desired optical and electromagnetic properties for optimal device performance. Purified deoxyribonucleic acid (DNA), derived from salmon sperm, has been investigated for use as an optical waveguide material. In this paper we present the materials processing and optical and electromagnetic characterization of this purified DNA to render a high quality, low loss optical waveguide material.

  2. Demonstration of four immunoassay formats using the array biosensor

    NASA Technical Reports Server (NTRS)

    Sapsford, Kim E.; Charles, Paul T.; Patterson, Charles H Jr; Ligler, Frances S.

    2002-01-01

    The ability of a fluorescence-based array biosensor to measure and quantify the binding of an antigen to an immobilized antibody has been demonstrated using the four different immunoassay formats: direct, competitive, displacement, and sandwich. A patterned array of antibodies specific for 2,4,6-trinitrotoluene (TNT) immobilized onto the surface of a planar waveguide and used to measure signals from different antigen concentrations simultaneously. For direct, competitive, and displacement assays, which are one-step assays, measurements were obtained in real time. Dose-response curves were calculated for all four assay formats, demonstrating the array biosensor's ability to quantify the amount of antigen present in solution.

  3. Synthetic Engineering of Spider Silk Fiber as Implantable Optical Waveguides for Low-Loss Light Guiding.

    PubMed

    Qiao, Xin; Qian, Zhigang; Li, Junjie; Sun, Hongji; Han, Yao; Xia, Xiaoxia; Zhou, Jin; Wang, Chunlan; Wang, Yan; Wang, Changyong

    2017-05-03

    A variety of devices used for biomedical engineering have been fabricated using protein polymer because of their excellent properties, such as strength, toughness, biocompatibility, and biodegradability. In this study, we fabricated an optical waveguide using genetically engineered spider silk protein. This method has two significant advantages: (1) recombinant spider silk optical waveguide exhibits excellent optical and biological properties and (2) biosynthesis of spider silk protein can overcome the limitation to the research on spider silk optical waveguide due to the low yield of natural spider silk. In detail, two kinds of protein-based optical waveguides made from recombinant spider silk protein and regenerative silkworm silk protein were successfully prepared. Results suggested that the recombinant spider silk optical waveguide showed a smoother surface and a higher refractive index when compared with regenerative silkworm silk protein. The optical loss of recombinant spider silk optical waveguide was 0.8 ± 0.1 dB/cm in air and 1.9 ± 0.3 dB/cm in mouse muscles, which were significantly lower than those of regenerative silkworm silk optical waveguide. Moreover, recombinant spider silk optical waveguide can meet the demand to guide and efficiently deliver light through biological tissue. In addition, recombinant spider silk optical waveguide showed low toxicity to cells in vitro and low-level inflammatory reaction with surrounding tissue in vivo. Therefore, recombinant spider silk optical waveguide is a promising implantable device to guide and deliver light with low loss.

  4. High Bandwidth Optical Links for Micro-Satellite Support

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin (Inventor); Wilson, Keith E. (Inventor); Coste, Keith (Inventor)

    2016-01-01

    A method, systems, apparatus and device enable high bandwidth satellite communications. An onboard tracking detector, installed in a low-earth orbit satellite, detects a position of an incoming optical beam received/transmitted from a first ground station of one or more ground stations. Tracker electronics determine orientation information of the incoming optical beam based on the position. Control electronics receive the orientation information from the tracker electronics, and control a waveguide drive electronics. The waveguide drive electronics control a voltage that is provided to an electro-optic waveguide beam steering device. The electro-optic waveguide beam steering device steers an outgoing optical beam to one of the one or more ground stations based on the voltage.

  5. Anti resonant reflecting optical waveguide structure based on oxidized porous silicon for label free bio sensing applications

    NASA Astrophysics Data System (ADS)

    Haji, L.; Hiraoui, M.; Lorrain, N.; Guendouz, M.

    2012-03-01

    In this letter we report on the use of an electrochemical process for the fabrication of anti resonant reflecting optical waveguide based on oxidized porous silicon. This method is known to allow the formation of various photonic structures (Bragg mirror, microcavity), thanks to the easy and in situ modulation of the porosity and thus of the refractive index. Planar anti resonant reflecting optical waveguide structure made from porous silicon is demonstrated to be very effective for low losses as compared to conventional resonant waveguide. Optical measurements carried out for TE and TM polarizations are reported and related to optical sensing.

  6. Single-mode glass waveguide technology for optical interchip communication on board level

    NASA Astrophysics Data System (ADS)

    Brusberg, Lars; Neitz, Marcel; Schröder, Henning

    2012-01-01

    The large bandwidth demand in long-distance telecom networks lead to single-mode fiber interconnects as result of low dispersion, low loss and dense wavelength multiplexing possibilities. In contrast, multi-mode interconnects are suitable for much shorter lengths up to 300 meters and are promising for optical links between racks and on board level. Active optical cables based on multi-mode fiber links are at the market and research in multi-mode waveguide integration on board level is still going on. Compared to multi-mode, a single-mode waveguide has much more integration potential because of core diameters of around 20% of a multi-mode waveguide by a much larger bandwidth. But light coupling in single-mode waveguides is much more challenging because of lower coupling tolerances. Together with the silicon photonics technology, a single-mode waveguide technology on board-level will be the straight forward development goal for chip-to-chip optical interconnects integration. Such a hybrid packaging platform providing 3D optical single-mode links bridges the gap between novel photonic integrated circuits and the glass fiber based long-distance telecom networks. Following we introduce our 3D photonic packaging approach based on thin glass substrates with planar integrated optical single-mode waveguides for fiber-to-chip and chip-to-chip interconnects. This novel packaging approach merges micro-system packaging and glass integrated optics. It consists of a thin glass substrate with planar integrated singlemode waveguide circuits, optical mirrors and lenses providing an integration platform for photonic IC assembly and optical fiber interconnect. Thin glass is commercially available in panel and wafer formats and characterizes excellent optical and high-frequency properties. That makes it perfect for microsystem packaging. The paper presents recent results in single-mode waveguide technology on wafer level and waveguide characterization. Furthermore the integration in a hybrid packaging process and design issues are discussed.

  7. Planar polymer and glass graded index waveguides for data center applications

    NASA Astrophysics Data System (ADS)

    Pitwon, Richard; Yamauchi, Akira; Brusberg, Lars; Wang, Kai; Ishigure, Takaaki; Schröder, Henning; Neitz, Marcel; Worrall, Alex

    2016-03-01

    Embedded optical waveguide technology for optical printed circuit boards (OPCBs) has advanced considerably over the past decade both in terms of materials and achievable waveguide structures. Two distinct classes of planar graded index multimode waveguide have recently emerged based on polymer and glass materials. We report on the suitability of graded index polymer waveguides, fabricated using the Mosquito method, and graded index glass waveguides, fabricated using ion diffusion on thin glass foils, for deployment within future data center environments as part of an optically disaggregated architecture. To this end, we first characterize the wavelength dependent performance of different waveguide types to assess their suitability with respect to two dominant emerging multimode transceiver classes based on directly modulated 850 nm VCSELs and 1310 silicon photonics devices. Furthermore we connect the different waveguide types into an optically disaggregated data storage system and characterize their performance with respect to different common high speed data protocols used at the intra and inter rack level including 10 Gb Ethernet and Serial Attached SCSI.

  8. Integrated optical gyroscopes offering low cost, small size and vibration immunity

    NASA Astrophysics Data System (ADS)

    Monovoukas, Christos; Swiecki, Andrew; Maseeh, Fariborz

    2000-03-01

    IntelliSense has developed an integrated optic gyro technology that provides the sensitivity of fiber optic gyros while utilizing batch microfabrication techniques to achieve the low cost of mechanical MEMS gyros. The base technology consists of an optical resonating waveguide chip, sensor electronics and an optical bench. The sensing element is based on an integrated optic waveguide chip in which counter-propagating optical fields are used to sense rotation in the plane of the waveguide through the Sagnac effect. It is powered by a semiconductor laser light source, which is coupled into a waveguide and split into two waveguide arms. Both signals are probed through the out coupled light at each waveguide arm, and rate information is derived from the difference in phase between these two signals. Measuring angular rotation is important for proper operation of a variety of systems such as: missile guidance systems, satellites, energy exploration, camera stabilization, robotics positioning, platform stabilization and space craft guidance to mention a few. This technology overcomes the limitations that previous commercially available gyros for this purpose have had including limitations in size, sensitivity, durability, and premium price.

  9. Silicon-on-insulator multimode-interference waveguide-based arrayed optical tweezers (SMART) for two-dimensional microparticle trapping and manipulation.

    PubMed

    Lei, Ting; Poon, Andrew W

    2013-01-28

    We demonstrate two-dimensional optical trapping and manipulation of 1 μm and 2.2 μm polystyrene particles in an 18 μm-thick fluidic cell at a wavelength of 1565 nm using the recently proposed Silicon-on-insulator Multimode-interference (MMI) waveguide-based ARrayed optical Tweezers (SMART) technique. The key component is a 100 μm square-core silicon waveguide with mm length. By tuning the fiber-coupling position at the MMI waveguide input facet, we demonstrate various patterns of arrayed optical tweezers that enable optical trapping and manipulation of particles. We numerically simulate the physical mechanisms involved in the arrayed trap, including the optical force, the heat transfer and the thermal-induced microfluidic flow.

  10. Near infrared optical biosensor based on peptide functionalized single-walled carbon nanotubes hybrids for 2,4,6-trinitrotoluene (TNT) explosive detection.

    PubMed

    Wang, Jin

    2018-06-01

    A near infrared (NIR) optical biosensor based on peptide functionalized single-walled carbon nanotubes (SWCNTs) hybrids for 2,4,6-trinitrotoluene (TNT) explosive detection was developed. The TNT binding peptide was directly anchored on the sidewall of the SWCNTs using the π-π interaction between the aromatic amino acids and SWCNTs, forming the peptide-SWCNTs hybrids for near infrared absorption spectra measurement. The evidence of the morphology of peptide-SWCNTs hybrids was obtained using atomic force microscopy (AFM). The results demonstrated that peptide-SWCNTs hybrids based NIR optical biosensor exhibited sensitive and highly selective for TNT explosive determination, addressing a promising optical biosensor for security application. Copyright © 2018. Published by Elsevier Inc.

  11. High-speed electro-optic switch based on nonlinear polymer-clad waveguide incorporated with quasi-in-plane coplanar waveguide electrodes

    NASA Astrophysics Data System (ADS)

    Jiang, Ming-Hui; Wang, Xi-Bin; Xu, Qiang; Li, Ming; Niu, Dong-Hai; Sun, Xiao-Qiang; Wang, Fei; Li, Zhi-Yong; Zhang, Da-Ming

    2018-01-01

    Nonlinear optical (NLO) polymer is a promising material for active waveguide devices that can provide large bandwidth and high-speed response time. However, the performance of the active devices is not only related to the waveguide materials, but also related to the waveguide and electrode structures. In this paper, a high-speed Mach-Zehnder interferometer (MZI) type of electro-optic (EO) switch based on NLO polymer-clad waveguide was fabricated. The quasi-in-plane coplanar waveguide electrodes were also introduced to enhance the poling and modulating efficiency. The characteristic parameters of the waveguide and electrode were carefully designed and simulated. The switches were fabricated by the conventional micro-fabrication process. Under 1550-nm operating wavelength, a typical fabricated switch showed a low insertion loss of 10.2 dB, and the switching rise time and fall time were 55.58 and 57.98 ns, respectively. The proposed waveguide and electrode structures could be developed into other active EO devices and also used as the component in the polymer-based large-scale photonic integrated circuit.

  12. On-chip optical mode conversion based on dynamic grating in photonic-phononic hybrid waveguide

    PubMed Central

    Chen, Guodong; Zhang, Ruiwen; Sun, Junqiang

    2015-01-01

    We present a scheme for reversible and tunable on-chip optical mode conversion based on dynamic grating in a hybrid photonic-phononic waveguide. The dynamic grating is built up through the acousto-optic effect and the theoretical model of the optical mode conversion is developed by considering the geometrical deformation and refractive index change. Three kinds of mode conversions are able to be realized using the same hybrid waveguide structure in a large bandwidth by only changing the launched acoustic frequency. The complete mode conversion can be achieved by choosing a proper acoustic power under a given waveguide length. PMID:25996236

  13. Optical sensor in planar configuration based on multimode interference

    NASA Astrophysics Data System (ADS)

    Blahut, Marek

    2017-08-01

    In the paper a numerical analysis of optical sensors based on multimode interference in planar one-dimensional step-index configuration is presented. The structure consists in single-mode input and output waveguides and multimode waveguide which guide only few modes. Material parameters discussed refer to a SU8 polymer waveguide on SiO2 substrate. The optical system described will be designed to the analysis of biological substances.

  14. Last Advances in Silicon-Based Optical Biosensors.

    PubMed

    Fernández Gavela, Adrián; Grajales García, Daniel; Ramirez, Jhonattan C; Lechuga, Laura M

    2016-02-24

    We review the most important achievements published in the last five years in the field of silicon-based optical biosensors. We focus specially on label-free optical biosensors and their implementation into lab-on-a-chip platforms, with an emphasis on developments demonstrating the capability of the devices for real bioanalytical applications. We report on novel transducers and materials, improvements of existing transducers, new and improved biofunctionalization procedures as well as the prospects for near future commercialization of these technologies.

  15. Intensity-based readout of resonant-waveguide grating biosensors: Systems and nanostructures

    NASA Astrophysics Data System (ADS)

    Paulsen, Moritz; Jahns, Sabrina; Gerken, Martina

    2017-09-01

    Resonant waveguide gratings (RWG) - also called photonic crystal slabs (PCS) - have been established as reliable optical transducers for label-free biochemical assays as well as for cell-based assays. Current readout systems are based on mechanical scanning and spectrometric measurements with system sizes suitable for laboratory equipment. Here, we review recent progress in compact intensity-based readout systems for point-of-care (POC) applications. We briefly introduce PCSs as sensitive optical transducers and introduce different approaches for intensity-based readout systems. Photometric measurements have been realized with a simple combination of a light source and a photodetector. Recently a 96-channel, intensity-based readout system for both biochemical interaction analyses as well as cellular assays was presented employing the intensity change of a near cut-off mode. As an alternative for multiparametric detection, a camera system for imaging detection has been implemented. A portable, camera-based system of size 13 cm × 4.9 cm × 3.5 cm with six detection areas on an RWG surface area of 11 mm × 7 mm has been demonstrated for the parallel detection of six protein binding kinetics. The signal-to-noise ratio of this system corresponds to a limit of detection of 168 M (24 ng/ml). To further improve the signal-to-noise ratio advanced nanostructure designs are investigated for RWGs. Here, results on multiperiodic and deterministic aperiodic nanostructures are presented. These advanced nanostructures allow for the design of the number and wavelengths of the RWG resonances. In the context of intensity-based readout systems they are particularly interesting for the realization of multi-LED systems. These recent trends suggest that compact point-of-care systems employing disposable test chips with RWG functional areas may reach market in the near future.

  16. Multicomponent micropatterned sol-gel materials by capillary molding

    NASA Astrophysics Data System (ADS)

    Lochhead, Michael J.; Yager, Paul

    1997-10-01

    A physically and chemically benign method for patterning multiple sol-gel materials onto a single substrate is described. Structures are demonstrated for potential micro- optical chemical sensor, biosensor, and waveguiding applications. Fabrication is based on the micro molding in capillaries (MIMIC) approach. A novel mold design allows several sols to be cast simultaneously. Closely spaced, organically modified silica ridges containing fluorescent dyes are demonstrated. Ridges have cross sectional dimensions from one to 50 micrometers and are centimeters in length. Processing issues, particularly those related to mold filling, are discussed in detail. Because sol-gel MIMIC avoids the harsh physical and chemical environments normally associated with patterning, the approach allows full exploitation of sol- gel processing advantages, such as the ability to entrap sensitive organic dopant molecules in the sol-gel matrix.

  17. Low-cost fabrication of optical waveguides, interconnects and sensing structures on all-polymer-based thin foils

    NASA Astrophysics Data System (ADS)

    Rezem, Maher; Kelb, Christian; Günther, Axel; Rahlves, Maik; Reithmeier, Eduard; Roth, Bernhard

    2016-03-01

    Micro-optical sensors based on optical waveguides are widely used to measure temperature, force and strain but also to detect biological and chemical substances such as explosives or toxins. While optical micro-sensors based on silicon technology require complex and expensive process technologies, a new generation of sensors based completely on polymers offer advantages especially in terms of low-cost and fast production techniques. We have developed a process to integrate micro-optical components such as embedded waveguides and optical interconnects into polymer foils with a thickness well below one millimeter. To enable high throughput production, we employ hot embossing technology, which is capable of reel-to-reel fabrication with a surface roughness in the optical range. For the waveguide fabrication, we used the thermoplastic polymethylmethacrylate (PMMA) as cladding and several optical adhesives as core materials. The waveguides are characterized with respect to refractive indices and propagation losses. We achieved propagation losses are as low as 0.3 dB/cm. Furthermore, we demonstrate coupling structures and their fabrication especially suited to integrate various light sources such as vertical-cavity surface-emitting lasers (VCSEL) and organic light emitting diodes (OLED) into thin polymer foils. Also, we present a concept of an all-polymer and waveguide based deformation sensor based on intensity modulation, which can be fabricated by utilizing our process. For future application, we aim at a low-cost and high-throughput reel-to-reel production process enabling the fabrication of large sensor arrays or disposable single-use sensing structures, which will open optical sensing to a large variety of application fields ranging from medical diagnosis to automotive sensing.

  18. Noble metal nanostructures in optical biosensors: Basics, and their introduction to anti-doping detection.

    PubMed

    Malekzad, Hedieh; Zangabad, Parham Sahandi; Mohammadi, Hadi; Sadroddini, Mohsen; Jafari, Zahra; Mahlooji, Niloofar; Abbaspour, Somaye; Gholami, Somaye; Ghanbarpoor, Mana; Pashazadeh, Rahim; Beyzavi, Ali; Karimi, Mahdi; Hamblin, Michael R

    2018-03-01

    Nanotechnology has illustrated significant potentials in biomolecular-sensing applications; particularly its introduction to anti-doping detection is of great importance. Illicit recreational drugs, substances that can be potentially abused, and drugs with dosage limitations according to the prohibited lists announced by the World Antidoping Agency (WADA) are becoming of increasing interest to forensic chemists. In this review, the theoretical principles of optical biosensors based on noble metal nanoparticles, and the transduction mechanism of commonly-applied plasmonic biosensors are covered. We review different classes of recently-developed plasmonic biosensors for analytic determination and quantification of illicit drugs in anti-doping applications. The important classes of illicit drugs include anabolic steroids, opioids, stimulants, and peptide hormones. The main emphasis is on the advantages that noble metal nano-particles bring to optical biosensors for signal enhancement and the development of highly sensitive (label-free) biosensors. In the near future, such optical biosensors may be an invaluable substitute for conventional anti-doping detection methods such as chromatography-based approaches, and may even be commercialized for routine anti-doping tests.

  19. Optical-fiber-to-waveguide coupling using carbon-dioxide-laser-induced long-period fiber gratings.

    PubMed

    Bachim, Brent L; Ogunsola, Oluwafemi O; Gaylord, Thomas K

    2005-08-15

    Optical fibers are expected to play a role in chip-level and board-level optical interconnects because of limitations on the bandwidth and level of integration of electrical interconnects. Therefore, methods are needed to couple optical fibers directly to waveguides on chips and on boards. We demonstrate optical-fiber-to-waveguide coupling using carbon-dioxide laser-induced long-period fiber gratings (LPFGs). Such gratings can be written in standard fiber and offer wavelength multiplexing-demultiplexing performance. The coupler fabrication process and the characterization apparatus are presented. The operation and the wavelength response of a LPFG-based optical-fiber-to-waveguide directional coupler are demonstrated.

  20. Development of a bacteriophage displayed peptide library and biosensor

    NASA Astrophysics Data System (ADS)

    Chin, Robert C.; Salazar, Noe; Mayo, Michael W.; Villavicencio, Victor I.; Taylor, Richard B.; Chambers, James P.; Valdes, James J.

    1996-04-01

    A miniaturized, handheld biosensor for identification of hazardous biowarfare agents with high specificity is being developed. An innovative biological recognition system based on bacteriophage displayed peptide receptors will be utilized in conjunction with the miniature biosensor technology being developed. A bacteriophage library has been constructed to provide the artificial receptors. The library can contain millions of bacteriophage with randomly displayed peptide sequences in the phage outer protein coat which act as binding sites for the agents of interest. This library will be used to 'bio-pan' for phages that bind to a number of toxins and infectious agents and can, thus, provide an endless supply of low cost, reliable, specific, and stable artificial receptors. The biosensor instrument will utilize evanescent wave, planar waveguide, far-red dyes, diode laser and miniature circuit technologies for performance and portability.

  1. Wavelength-addressed intra-board optical interconnection by plug-in alignment with a micro hole array

    NASA Astrophysics Data System (ADS)

    Nakama, Kenichi; Tokiwa, Yuu; Mikami, Osamu

    2010-09-01

    Intra-board interconnection between optical waveguide channels is suitable for assembling high-speed optoelectronic printed wiring boards (OE-PWB). Here, we propose a novel optical interconnection method combining techniques for both wavelength-based optical waveguide addressing and plug-in optical waveguide alignment with a micro-hole array (MHA). This array was fabricated by the mask transfer method. For waveguide addressing, we used a micro passive wavelength selector (MPWS) module, which is a type of Littrow mount monochromator consisting of an optical diffraction grating, a focusing lens, and the MHA. From the experimental results, we found that the wavelength addressing operation of the MPWS module was effective for intra-board optical interconnection.

  2. Capillary waveguide optrodes: an approach to optical sensing in medical diagnostics

    NASA Astrophysics Data System (ADS)

    Lippitsch, Max E.; Draxler, Sonja; Kieslinger, Dietmar; Lehmann, Hartmut; Weigl, Bernhard H.

    1996-07-01

    Glass capillaries with a chemically sensitive coating on the inner surface are used as optical sensors for medical diagnostics. A capillary simultaneously serves as a sample compartment, a sensor element, and an inhomogeneous optical waveguide. Various detection schemes based on absorption, fluorescence intensity, or fluorescence lifetime are described. In absorption-based capillary waveguide optrodes the absorption in the sensor layer is analyte dependent; hence light transmission along the inhomogeneous waveguiding structure formed by the capillary wall and the sensing layer is a function of the analyte concentration. Similarly, in fluorescence-based capillary optrodes the fluorescence intensity or the fluorescence lifetime of an indicator dye fixed in the sensing layer is analyte dependent; thus the specific property of fluorescent light excited in the sensing layer and thereafter guided along the inhomogeneous waveguiding structure is a function of the analyte concentration. Both schemes are experimentally demonstrated, one with carbon dioxide as the analyte and the other one with oxygen. The device combines optical sensors with the standard glass capillaries usually applied to gather blood drops from fingertips, to yield a versatile diagnostic instrument, integrating the sample compartment, the optical sensor, and the light-collecting optics into a single piece. This ensures enhanced sensor performance as well as improved handling compared with other sensors. waveguide, blood gases, medical diagnostics.

  3. Last Advances in Silicon-Based Optical Biosensors

    PubMed Central

    Fernández Gavela, Adrián; Grajales García, Daniel; Ramirez, Jhonattan C.; Lechuga, Laura M.

    2016-01-01

    We review the most important achievements published in the last five years in the field of silicon-based optical biosensors. We focus specially on label-free optical biosensors and their implementation into lab-on-a-chip platforms, with an emphasis on developments demonstrating the capability of the devices for real bioanalytical applications. We report on novel transducers and materials, improvements of existing transducers, new and improved biofunctionalization procedures as well as the prospects for near future commercialization of these technologies. PMID:26927105

  4. Assembly of optical fibers for the connection of polymer-based waveguide

    NASA Astrophysics Data System (ADS)

    Ansel, Yannick; Grau, Daniel; Holzki, Markus; Kraus, Silvio; Neumann, Frank; Reinhard, Carsten; Schmitz, Felix

    2003-03-01

    This paper describes the realization of polymer-based optical structures and the assembly and packaging strategy to connect optical fiber ribbons to the waveguides. For that a low cost fabrication process using the SU-8TM thick photo-resist is presented. This process consists in the deposition of two photo-structurized resist layers filled up with epoxy glue realising the core waveguide. For the assembly, a new modular vacuum gripper was realised and installed on an automatic pick and place assembly robot to mount precisely and efficiently the optical fibers in the optical structures. First results have shown acceptable optical propagation loss for the complete test structure.

  5. Integrated resonant micro-optical gyroscope and method of fabrication

    DOEpatents

    Vawter, G Allen [Albuquerque, NM; Zubrzycki, Walter J [Sandia Park, NM; Guo, Junpeng [Albuquerque, NM; Sullivan, Charles T [Albuquerque, NM

    2006-09-12

    An integrated optic gyroscope is disclosed which is based on a photonic integrated circuit (PIC) having a bidirectional laser source, a pair of optical waveguide phase modulators and a pair of waveguide photodetectors. The PIC can be connected to a passive ring resonator formed either as a coil of optical fiber or as a coiled optical waveguide. The lasing output from each end of the bidirectional laser source is phase modulated and directed around the passive ring resonator in two counterpropagating directions, with a portion of the lasing output then being detected to determine a rotation rate for the integrated optical gyroscope. The coiled optical waveguide can be formed on a silicon, glass or quartz substrate with a silicon nitride core and a silica cladding, while the PIC includes a plurality of III V compound semiconductor layers including one or more quantum well layers which are disordered in the phase modulators and to form passive optical waveguides.

  6. Carp vitellogenin detection by an optical waveguide lightmode spectroscopy biosensor.

    PubMed

    Kim, Namsoo; Kim, Dong-Kyung; Cho, Yong-Jin; Moon, Dae-Kyung; Kim, Woo-Yeon

    2008-11-15

    A label-free carp vitellogenin sensor has a strong potential for on-site monitoring on the possible contamination of edible fish with endocrine disruptors as a sum parameter in an inland carp farm. In this study, we performed a sensitive detection for carp vitellogenin with a direct-binding optical waveguide lightmode spectroscopy-based immunosensor. Carp vitellogenin bound over the sensor surface quite specifically, judging from the sensor responses according to stepwise antibody immobilization. This was also supported by a negligible sensor response found at bovine serum albumin immobilization. When plotted in double-logarithmic scale for carp vitellogenin concentrations of 0.00675-67.5 nM, a linear relationship was found between analyte concentration and sensor response, together with the limit of detection of 0.00675 nM. The reusability of the immunosensor after the regeneration with 10mM HCl was reasonably good, as presumed from the coefficient of variability of 6.02% for nine repetitive measurements. The model sample prepared by spiking a purified carp vitellogenin into a 10-fold diluted vitellogenin-free carp serum in 9.45 nM showed the response ratio of 96.70% against 9.45 nM of the purified carp vitellogenin. When a female and male carp sera induced with 17beta-estradiol injection were analyzed, biomarker induction was even identifiable at 2000-fold serum dilution.

  7. Total internal reflection-based planar waveguide solar concentrator with symmetric air prisms as couplers.

    PubMed

    Xie, Peng; Lin, Huichuan; Liu, Yong; Li, Baojun

    2014-10-20

    We present a waveguide coupling approach for planar waveguide solar concentrator. In this approach, total internal reflection (TIR)-based symmetric air prisms are used as couplers to increase the coupler reflectivity and to maximize the optical efficiency. The proposed concentrator consists of a line focusing cylindrical lens array over a planar waveguide. The TIR-based couplers are located at the focal line of each lens to couple the focused sunlight into the waveguide. The optical system was modeled and simulated with a commercial ray tracing software (Zemax). Results show that the system used with optimized TIR-based couplers can achieve 70% optical efficiency at 50 × geometrical concentration ratio, resulting in a flux concentration ratio of 35 without additional secondary concentrator. An acceptance angle of ± 7.5° is achieved in the x-z plane due to the use of cylindrical lens array as the primary concentrator.

  8. Thin glass based packaging and photonic single-mode waveguide integration by ion-exchange technology on board and module level

    NASA Astrophysics Data System (ADS)

    Brusberg, Lars; Lang, Günter; Schröder, Henning

    2011-01-01

    The proposed novel packaging approach merges micro-system packaging and glass integrated optics. It provides 3D optical single-mode intra system links to bridge the gap between novel photonic integrated circuits and the glass fibers for inter system interconnects. We introduce our hybrid 3D photonic packaging approach based on thin glass substrates with planar integrated optical single-mode waveguides for fiber-to-chip and chip-to-chip links. Optical mirrors and lenses provide optical mode matching for photonic IC assemblies and optical fiber interconnects. Thin glass is commercially available in panel and wafer formats and characterizes excellent optical and high-frequency properties as reviewed in the paper. That makes it perfect for micro-system packaging. The adopted planar waveguide process based on ion-exchange technology is capable for high-volume manufacturing. This ion-exchange process and the optical propagation are described in detail for thin glass substrates. An extensive characterization of all basic circuit elements like straight and curved waveguides, couplers and crosses proves the low attenuation of the optical circuit elements.

  9. Realization of optical multimode TSV waveguides for Si-Interposer in 3D-chip-stacks

    NASA Astrophysics Data System (ADS)

    Killge, S.; Charania, S.; Richter, K.; Neumann, N.; Al-Husseini, Z.; Plettemeier, D.; Bartha, J. W.

    2017-05-01

    Optical connectivity has the potential to outperform copper-based TSVs in terms of bandwidth at the cost of more complexity due to the required electro-optical and opto-electrical conversion. The continuously increasing demand for higher bandwidth pushes the breakeven point for a profitable operation to shorter distances. To integrate an optical communication network in a 3D-chip-stack optical through-silicon vertical VIAs (TSV) are required. While the necessary effort for the electrical/optical and vice versa conversion makes it hard to envision an on-chip optical interconnect, a chip-to-chip optical link appears practicable. In general, the interposer offers the potential advantage to realize electro-optical transceivers on affordable expense by specific, but not necessarily CMOS technology. We investigated the realization and characterization of optical interconnects as a polymer based waveguide in high aspect ratio (HAR) TSVs proved on waferlevel. To guide the optical field inside a TSV as optical-waveguide or fiber, its core has to have a higher refractive index than the surrounding material. Comparing different material / technology options it turned out that thermal grown silicon dioxide (SiO2) is a perfect candidate for the cladding (nSiO2 = 1.4525 at 850 nm). In combination with SiO2 as the adjacent polymer layer, the negative resist SU-8 is very well suited as waveguide material (nSU-8 = 1.56) for the core. Here, we present the fabrication of an optical polymer based multimode waveguide in TSVs proved on waferlevel using SU-8 as core and SiO2 as cladding. The process resulted in a defect-free filling of waveguide TSVs with SU-8 core and SiO2 cladding up to aspect ratio (AR) 20:1 and losses less than 3 dB.

  10. Mechanical Kerr nonlinearities due to bipolar optical forces between deformable silicon waveguides.

    PubMed

    Ma, Jing; Povinelli, Michelle L

    2011-05-23

    We use an analytical method based on the perturbation of effective index at fixed frequency to calculate optical forces between silicon waveguides. We use the method to investigate the mechanical Kerr effect in a coupled-waveguide system with bipolar forces. We find that a positive mechanical Kerr coefficient results from either an attractive or repulsive force. An enhanced mechanical Kerr coefficient several orders of magnitude larger than the intrinsic Kerr coefficient is obtained in waveguides for which the optical mode approaches the air light line, given appropriate design of the waveguide dimensions.

  11. Transverse writing of three-dimensional tubular optical waveguides in glass with a slit-shaped femtosecond laser beam

    PubMed Central

    Liao, Yang; Qi, Jia; Wang, Peng; Chu, Wei; Wang, Zhaohui; Qiao, Lingling; Cheng, Ya

    2016-01-01

    We report on fabrication of tubular optical waveguides buried in ZBLAN glass based on transverse femtosecond laser direct writing. Irradiation in ZBLAN with focused femtosecond laser pulses leads to decrease of refractive index in the modified region. Tubular optical waveguides of variable mode areas are fabricated by forming the four sides of the cladding with slit-shaped femtosecond laser pulses, ensuring single mode waveguiding with a mode field dimension as small as ~4 μm. PMID:27346285

  12. Optical microwave filter based on spectral slicing by use of arrayed waveguide gratings.

    PubMed

    Pastor, Daniel; Ortega, Beatriz; Capmany, José; Sales, Salvador; Martinez, Alfonso; Muñoz, Pascual

    2003-10-01

    We have experimentally demonstrated a new optical signal processor based on the use of arrayed waveguide gratings. The structure exploits the concept of spectral slicing combined with the use of an optical dispersive medium. The approach presents increased flexibility from previous slicing-based structures in terms of tunability, reconfiguration, and apodization of the samples or coefficients of the transversal optical filter.

  13. International Conference on Integrated Optical Circuit Engineering, 1st, Cambridge, MA, October 23-25, 1984, Proceedings

    NASA Astrophysics Data System (ADS)

    Ostrowsky, D. B.; Sriram, S.

    Aspects of waveguide technology are explored, taking into account waveguide fabrication techniques in GaAs/GaAlAs, the design and fabrication of AlGaAs/GaAs phase couplers for optical integrated circuit applications, ion implanted GaAs integrated optics fabrication technology, a direct writing electron beam lithography based process for the realization of optoelectronic integrated circuits, and advances in the development of semiconductor integrated optical circuits for telecommunications. Other subjects examined are related to optical signal processing, optical switching, and questions of optical bistability and logic. Attention is given to acousto-optic techniques in integrated optics, acousto-optic Bragg diffraction in proton exchanged waveguides, optical threshold logic architectures for hybrid binary/residue processors, integrated optical modulation and switching, all-optic logic devices for waveguide optics, optoelectronic switching, high-speed photodetector switching, and a mechanical optical switch.

  14. Broadband and scalable optical coupling for silicon photonics using polymer waveguides

    NASA Astrophysics Data System (ADS)

    La Porta, Antonio; Weiss, Jonas; Dangel, Roger; Jubin, Daniel; Meier, Norbert; Horst, Folkert; Offrein, Bert Jan

    2018-04-01

    We present optical coupling schemes for silicon integrated photonics circuits that account for the challenges in large-scale data processing systems such as those used for emerging big data workloads. Our waveguide based approach allows to optimally exploit the on-chip optical feature size, and chip- and package real-estate. It further scales well to high numbers of channels and is compatible with state-of-the-art flip-chip die packaging. We demonstrate silicon waveguide to polymer waveguide coupling losses below 1.5 dB for both the O- and C-bands with a polarisation dependent loss of <1 dB. Over 100 optical silicon waveguide to polymer waveguide interfaces were assembled within a single alignment step, resulting in a physical I/O channel density of up to 13 waveguides per millimetre along the chip-edge, with an average coupling loss of below 3.4 dB measured at 1310 nm.

  15. Integrated Miniature Arrays of Optical Biomolecule Detectors

    NASA Technical Reports Server (NTRS)

    Iltchenko, Vladimir; Maleki, Lute; Lin, Ying; Le, Thanh

    2009-01-01

    Integrated miniature planar arrays of optical sensors for detecting specific biochemicals in extremely small quantities have been proposed. An array of this type would have an area of about 1 cm2. Each element of the array would include an optical microresonator that would have a high value of the resonance quality factor (Q . 107). The surface of each microresonator would be derivatized to make it bind molecules of a species of interest, and such binding would introduce a measurable change in the optical properties of the microresonator. Because each microresonator could be derivatized for detection of a specific biochemical different from those of the other microresonators, it would be possible to detect multiple specific biochemicals by simultaneous or sequential interrogation of all the elements in the array. Moreover, the derivatization would make it unnecessary to prepare samples by chemical tagging. Such interrogation would be effected by means of a grid of row and column polymer-based optical waveguides that would be integral parts of a chip on which the array would be fabricated. The row and column polymer-based optical waveguides would intersect at the elements of the array (see figure). At each intersection, the row and column waveguides would be optically coupled to one of the microresonators. The polymer-based waveguides would be connected via optical fibers to external light sources and photodetectors. One set of waveguides and fibers (e.g., the row waveguides and fibers) would couple light from the sources to the resonators; the other set of waveguides and fibers (e.g., the column waveguides and fibers) would couple light from the microresonators to the photodetectors. Each microresonator could be addressed individually by row and column for measurement of its optical transmission. Optionally, the chip could be fabricated so that each microresonator would lie inside a microwell, into which a microscopic liquid sample could be dispensed.

  16. High-Power, High-Speed Electro-Optic Pockels Cell Modulator

    NASA Technical Reports Server (NTRS)

    Hawthorne, Justin; Battle, Philip

    2013-01-01

    Electro-optic modulators rely on a change in the index of refraction for the optical wave as a function of an applied voltage. The corresponding change in index acts to delay the wavefront in the waveguide. The goal of this work was to develop a high-speed, high-power waveguide- based modulator (phase and amplitude) and investigate its use as a pulse slicer. The key innovation in this effort is the use of potassium titanyl phosphate (KTP) waveguides, making the highpower, polarization-based waveguide amplitude modulator possible. Furthermore, because it is fabricated in KTP, the waveguide component will withstand high optical power and have a significantly higher RF modulation figure of merit (FOM) relative to lithium niobate. KTP waveguides support high-power TE and TM modes - a necessary requirement for polarization-based modulation as with a Pockels cell. High-power fiber laser development has greatly outpaced fiber-based modulators in terms of its maturity and specifications. The demand for high-performance nonlinear optical (NLO) devices in terms of power handling, efficiency, bandwidth, and useful wavelength range has driven the development of bulk NLO options, which are limited in their bandwidth, as well as waveguide based LN modulators, which are limited by their low optical damage threshold. Today, commercially available lithium niobate (LN) modulators are used for laser formatting; however, because of photorefractive damage that can reduce transmission and increase requirements on bias control, LN modulators cannot be used with powers over several mW, dependent on wavelength. The high-power, high-speed modulators proposed for development under this effort will enable advancements in several exciting fields including lidarbased remote sensing, atomic interferometry, free-space laser communications, and others.

  17. All-optical switch with two periodically modulated nonlinear waveguides.

    PubMed

    Xie, Qiongtao; Luo, Xiaobing; Wu, Biao

    2010-02-01

    We propose a type of all-optical switch which consists of two periodically modulated nonlinear optical waveguides placed in parallel. Compared to the all-optical switch based on the traditional nonlinear directional coupler without periodic modulation, this all-optical switch has much lower switching threshold power and sharper switching width.

  18. FIBER AND INTEGRATED OPTICS: New method for determination of the parameters of a channel waveguide

    NASA Astrophysics Data System (ADS)

    Galechyan, M. G.; Dianov, Evgenii M.; Lyndin, N. M.; Sychugov, V. A.; Tishchenko, A. V.; Usievich, B. A.

    1992-02-01

    A new method for the determination of the parameters of channel integrated optical waveguides is proposed. This method is based on measuring the spectral transmission of a system comprising the investigated waveguide and single-mode fiber waveguides, which are brought into contact with the channel waveguide. The results are reported of an investigation of two channel waveguides formed in glass by a variety of methods and characterized by different refractive index profiles. The proposed method is found to be suitable for determination of the parameters of the refractive index profile of the investigated channel waveguides.

  19. Chalcogenide based rib waveguide for compact on-chip supercontinuum sources in mid-infrared domain

    NASA Astrophysics Data System (ADS)

    Saini, Than Singh; Tiwari, Umesh Kumar; Sinha, Ravindra Kumar

    2017-08-01

    We have designed and analysed a rib waveguide structure in recently reported Ga-Sb-S based highly nonlinear chalcogenide glass for nonlinear applications. The proposed waveguide structure possesses a very high nonlinear coefficient and can be used to generate broadband supercontinuum in mid-infrared domain. The reported design of the chalcogenide waveguide offers two zero dispersion values at 1800 nm and 2900 nm. Such rib waveguide structure is suitable to generate efficient supercontinuum generation ranging from 500 - 7400 μm. The reported waveguide can be used for the realization of the compact on-chip supercontinuum sources which are highly applicable in optical imaging, optical coherence tomography, food quality control, security and sensing.

  20. [Optical Design of Miniature Infrared Gratings Spectrometer Based on Planar Waveguide].

    PubMed

    Li, Yang-yu; Fang, Yong-hua; Li, Da-cheng; Liu, Yang

    2015-03-01

    In order to miniaturize an infrared spectrometer, we analyze the current optical design of miniature spectrometers and propose a method for designing a miniature infrared gratings spectrometer based on planar waveguide. Common miniature spectrometer uses miniature optical elements to reduce the size of system, which also shrinks the effective aperture. So the performance of spectrometer has dropped. Miniaturization principle of planar waveguide spectrometer is different from the principle of common miniature spectrometer. In planar waveguide spectrometer, the propagation of light is limited in a thin planar waveguide, which looks like the whole optical system is squashed flat. In the direction parallel to the planar waveguide, the light through the slit is collimated, dispersed and focused. And a spectral image is formed in the detector plane. This propagation of light is similar to the light in common miniature spectrometer. In the direction perpendicular to the planar waveguide, light is multiple reflected by the upper and lower surfaces of the planar waveguide and propagates in the waveguide. So the size of corresponding optical element could be very small in the vertical direction, which can reduce the size of the optical system. And the performance of the spectrometer is still good. The design method of the planar waveguide spectrometer can be separated into two parts, Czerny-Turner structure design and planar waveguide structure design. First, by using aberration theory an aberration-corrected (spherical aberration, coma, focal curve) Czerny-Turner structure is obtained. The operation wavelength range and spectral resolution are also fixed. Then, by using geometrical optics theory a planar waveguide structure is designed for reducing the system size and correcting the astigmatism. The planar waveguide structure includes a planar waveguide and two cylindrical lenses. Finally, they are modeled together in optical design software and are optimized as a whole. An infrared planar waveguide spectrometer is designed using this method. The operation wavelength range is 8 - 12 μm, the numerical aperture is 0.22, and the linear array detector contains 64 elements. By using Zemax software, the design is optimized and analyzed. The results indicate that the size of the optical system is 130 mm x 125 mm x 20 mm and the spectral resolution of spectrometer is 80 nm, which satisfy the requirements of design index. Thus it is this method that can be used for designing a miniature spectrometer without movable parts and sizes in the range of several cubic centimeters.

  1. FIBER AND INTEGRATED OPTICS: Matching of fiber and strip optical waveguides by graded-index optical matching components

    NASA Astrophysics Data System (ADS)

    Shmal'ko, A. V.; Gordova, M. R.; Lamekin, V. F.; Nikolaev, I. V.; Sakharov, V. V.; Smirnov, V. L.; Polyantsev, A. S.

    1990-01-01

    A method for selection and calculation of the parameters of axisymmetric and anamorphic graded-index lenses for optical matching devices is developed and tested. These devices are intended for detachable connectors joining single-mode fibers to strip optical waveguides and are characterized by a greater tolerance to a mismatch between these waveguides. An experimental study is reported of a prototype of an optical matching device based on graded-index lenses characterized by insertion losses from 1-3 dB.

  2. Nanophotonic label-free biosensors for environmental monitoring.

    PubMed

    Chocarro-Ruiz, Blanca; Fernández-Gavela, Adrián; Herranz, Sonia; Lechuga, Laura M

    2017-06-01

    The field of environmental monitoring has experienced a substantial progress in the last years but still the on-site control of contaminants is an elusive problem. In addition, the growing number of pollutant sources is accompanied by an increasing need of having efficient early warning systems. Several years ago biosensor devices emerged as promising environmental monitoring tools, but their level of miniaturization and their fully operation outside the laboratory prevented their use on-site. In the last period, nanophotonic biosensors based on evanescent sensing have emerged as an outstanding choice for portable point-of-care diagnosis thanks to their capability, among others, of miniaturization, multiplexing, label-free detection and integration in lab-on-chip platforms. This review covers the most relevant nanophotonic biosensors which have been proposed (including interferometric waveguides, grating-couplers, microcavity resonators, photonic crystals and localized surface plasmon resonance sensors) and their recent application for environmental surveillance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Chemical Sensors Based on Optical Ring Resonators

    NASA Technical Reports Server (NTRS)

    Homer, Margie; Manfreda, Allison; Mansour, Kamjou; Lin, Ying; Ksendzov, Alexander

    2005-01-01

    Chemical sensors based on optical ring resonators are undergoing development. A ring resonator according to this concept is a closed-circuit dielectric optical waveguide. The outermost layer of this waveguide, analogous to the optical cladding layer on an optical fiber, is a made of a polymer that (1) has an index of refraction lower than that of the waveguide core and (2) absorbs chemicals from the surrounding air. The index of refraction of the polymer changes with the concentration of absorbed chemical( s). The resonator is designed to operate with relatively strong evanescent-wave coupling between the outer polymer layer and the electromagnetic field propagating along the waveguide core. By virtue of this coupling, the chemically induced change in index of refraction of the polymer causes a measurable shift in the resonance peaks of the ring. In a prototype that has been used to demonstrate the feasibility of this sensor concept, the ring resonator is a dielectric optical waveguide laid out along a closed path resembling a racetrack (see Figure 1). The prototype was fabricated on a silicon substrate by use of standard techniques of thermal oxidation, chemical vapor deposition, photolithography, etching, and spin coating. The prototype resonator waveguide features an inner cladding of SiO2, a core of SixNy, and a chemical-sensing outer cladding of ethyl cellulose. In addition to the ring Chemical sensors based on optical ring resonators are undergoing development. A ring resonator according to this concept is a closed-circuit dielectric optical waveguide. The outermost layer of this waveguide, analogous to the optical cladding layer on an optical fiber, is a made of a polymer that (1) has an index of refraction lower than that of the waveguide core and (2) absorbs chemicals from the surrounding air. The index of refraction of the polymer changes with the concentration of absorbed chemical( s). The resonator is designed to operate with relatively strong evanescent-wave coupling between the outer polymer layer and the electromagnetic field propagating along the waveguide core. By virtue of this coupling, the chemically induced change in index of refraction of the polymer causes a measurable shift in the resonance peaks of the ring. In a prototype that has been used to demonstrate the feasibility of this sensor concept, the ring resonator is a dielectric optical waveguide laid out along a closed path resembling a racetrack (see Figure 1). The prototype was fabricated on a silicon substrate by use of standard techniques of thermal oxidation, chemical vapor deposition, photolithography, etching, and spin coating. The prototype resonator waveguide features an inner cladding of SiO2, a core of SixNy, and a chemical-sensing outer cladding of ethyl cellulose. In addition to the ring res

  4. A theoretical examination of the performances of wavelength multiplexers utilizing planar optical waveguides

    NASA Astrophysics Data System (ADS)

    Gomaa, M. L.; Chartier, G.

    1985-04-01

    The performances of distributed coupling wavelength multiplexer-demultiplexer devices for optical telecommunications applications, i.e., data transfer, are assessed theoretically. The values used for the refraction indices and waveguide dimensions are based on the ionic exchange between the glass layer and a base salt bath. Gradients in the indices are also considered. A shift of indices is assumed to be present between parallel waveguides of different thicknesses separated by a liquid bath. The behavior of the two waveguides is then the variations of the coupling and energy exchanged as functions of the wavelength transmitted. Attention is also given to the case of identical coupled waveguides.

  5. Polydimethylsiloxane-based optical waveguides for tetherless powering of floating microstimulators

    NASA Astrophysics Data System (ADS)

    Ersen, Ali; Sahin, Mesut

    2017-05-01

    Neural electrodes and associated electronics are powered either through percutaneous wires or transcutaneous powering schemes with energy harvesting devices implanted underneath the skin. For electrodes implanted in the spinal cord and the brain stem that experience large displacements, wireless powering may be an option to eliminate device failure by the breakage of wires and the tethering of forces on the electrodes. We tested the feasibility of using optically clear polydimethylsiloxane (PDMS) as a waveguide to collect the light in a subcutaneous location and deliver to deeper regions inside the body, thereby replacing brittle metal wires tethered to the electrodes with PDMS-based optical waveguides that can transmit energy without being attached to the targeted electrode. We determined the attenuation of light along the PDMS waveguides as 0.36±0.03 dB/cm and the transcutaneous light collection efficiency of cylindrical waveguides as 44%±11% by transmitting a laser beam through the thenar skin of human hands. We then implanted the waveguides in rats for a month to demonstrate the feasibility of optical transmission. The collection efficiency and longitudinal attenuation values reported here can help others design their own waveguides and make estimations of the waveguide cross-sectional area required to deliver sufficient power to a certain depth in tissue.

  6. Waveguide-based optical chemical sensor

    DOEpatents

    Grace, Karen M [Ranchos de Taos, NM; Swanson, Basil I [Los Alamos, NM; Honkanen, Seppo [Tucson, AZ

    2007-03-13

    The invention provides an apparatus and method for highly selective and sensitive chemical sensing. Two modes of laser light are transmitted through a waveguide, refracted by a thin film host reagent coating on the waveguide, and analyzed in a phase sensitive detector for changes in effective refractive index. Sensor specificity is based on the particular species selective thin films of host reagents which are attached to the surface of the planar optical waveguide. The thin film of host reagents refracts laser light at different refractive indices according to what species are forming inclusion complexes with the host reagents.

  7. Label-Free Biosensors Based on Bimodal Waveguide (BiMW) Interferometers.

    PubMed

    Herranz, Sonia; Gavela, Adrián Fernández; Lechuga, Laura M

    2017-01-01

    The bimodal waveguide (BiMW) sensor is a novel common path interferometric transducer based on the evanescent field detection principle, which in combination with a bio-recognition element allows the direct detection of biomolecular interactions in a label-free scheme. Due to its inherent high sensitivity it has great potential to become a powerful analytical tool for monitoring substances of interest in areas such as environmental control, medical diagnostics and food safety, among others. The BiMW sensor is fabricated using standard silicon-based technology allowing cost-effective production, and meeting the requirements of portability and disposability necessary for implementation in a point-of-care (POC) setting.In this chapter we describe the design and fabrication of the BiMW transducer, as well as its application for bio-sensing purposes. We show as an example the biosensor capabilities two different applications: (1) the immunodetection of Irgarol 1051 biocide useful in the environmental field, and (2) the detection of human growth hormone as used in clinical diagnostics. The detection is performed in real time by monitoring changes in the intensity pattern of light exiting the BiMW transducer resulting from antigen-antibody interactions on the surface of the sensor.

  8. Development of biosensors based on the one-dimensional semiconductor nanomaterials.

    PubMed

    Yan, Shancheng; Shi, Yi; Xiao, Zhongdang; Zhou, Minmin; Yan, Wenfu; Shen, Haoliang; Hu, Dong

    2012-09-01

    Biosensors are becoming increasingly important due to their applications in biological and chemical analyses, food safety industry, biomedical diagnostics, clinical detection, and environmental monitoring. Recent years, nanostructured semiconductor materials have been used to fabricate biosensors owing to their biocompatibility, low toxicity, high electron mobility, and easy fabrication. In the present study, we focus on recent various biosensors based on the one-dimensional semiconductor nanomaterials such as electrochemical biosensor, field-effect transistors biosensor, and label-free optical biosensor. In particular, the development of the electrochemical biosensor is discussed detailedly.

  9. Detection of antibody-antigen reaction by silicon nitride slot-ring biosensors using protein G

    NASA Astrophysics Data System (ADS)

    Taniguchi, Tomoya; Hirowatari, Anna; Ikeda, Takeshi; Fukuyama, Masataka; Amemiya, Yoshiteru; Kuroda, Akio; Yokoyama, Shin

    2016-04-01

    Biosensors using ring resonators with silicon nitride (SiN) slot waveguides have been fabricated. The temperature coefficient of the resonance wavelength of the SiN resonator is 0.006 nm/°C, which is one order of magnitude smaller than that of Si. The sensitivity of the biosensor has been improved by using slot waveguide together with Si-binding protein (designated as Si-tag), which bonds to SiN or SiO2 surface, as an anchoring molecule to immobilize bioreceptors on the SiN rings in an oriented manner. Furthermore, the protein G, which strongly bonds to many kinds of mammalian antibodies only by mixing the antibody solution, is used to efficiently immobilize the antigen on the sensor surface. By means of these devises the sensitivity of the biosensor has been improved by factor of 10-100 compared with that of normal Si ring resonator sensors without slot. Then the detection of prostate specific antigen (PSA) with the sensitivity of ~1×10-8 g/ml, which is the concentration of strongly suspicious for the prostate cancer, has been achieved.

  10. Electro-optical backplane demonstrator with integrated multimode gradient-index thin glass waveguide panel

    NASA Astrophysics Data System (ADS)

    Schröder, Henning; Brusberg, Lars; Pitwon, Richard; Whalley, Simon; Wang, Kai; Miller, Allen; Herbst, Christian; Weber, Daniel; Lang, Klaus-Dieter

    2015-03-01

    Optical interconnects for data transmission at board level offer increased energy efficiency, system density, and bandwidth scalability compared to purely copper driven systems. We present recent results on manufacturing of electrooptical printed circuit board (PCB) with integrated planar glass waveguides. The graded index multi-mode waveguides are patterned inside commercially available thin-glass panels by performing a specific ion-exchange process. The glass waveguide panel is embedded within the layer stack-up of a PCB using proven industrial processes. This paper describes the design, manufacture, assembly and characterization of the first electro-optical backplane demonstrator based on integrated planar glass waveguides. The electro-optical backplane in question is created by laminating the glass waveguide panel into a conventional multi-layer electronic printed circuit board stack-up. High precision ferrule mounts are automatically assembled, which will enable MT compliant connectors to be plugged accurately to the embedded waveguide interfaces on the glass panel edges. The demonstration platform comprises a standardized sub-rack chassis and five pluggable test cards each housing optical engines and pluggable optical connectors. The test cards support a variety of different data interfaces and can support data rates of up to 32 Gb/s per channel.

  11. Optical clock distribution in supercomputers using polyimide-based waveguides

    NASA Astrophysics Data System (ADS)

    Bihari, Bipin; Gan, Jianhua; Wu, Linghui; Liu, Yujie; Tang, Suning; Chen, Ray T.

    1999-04-01

    Guided-wave optics is a promising way to deliver high-speed clock-signal in supercomputer with minimized clock-skew. Si- CMOS compatible polymer-based waveguides for optoelectronic interconnects and packaging have been fabricated and characterized. A 1-to-48 fanout optoelectronic interconnection layer (OIL) structure based on Ultradel 9120/9020 for the high-speed massive clock signal distribution for a Cray T-90 supercomputer board has been constructed. The OIL employs multimode polymeric channel waveguides in conjunction with surface-normal waveguide output coupler and 1-to-2 splitters. Surface-normal couplers can couple the optical clock signals into and out from the H-tree polyimide waveguides surface-normally, which facilitates the integration of photodetectors to convert optical-signal to electrical-signal. A 45-degree surface- normal couplers has been integrated at each output end. The measured output coupling efficiency is nearly 100 percent. The output profile from 45-degree surface-normal coupler were calculated using Fresnel approximation. the theoretical result is in good agreement with experimental result. A total insertion loss of 7.98 dB at 850 nm was measured experimentally.

  12. Progress of new label-free techniques for biosensors: a review.

    PubMed

    Sang, Shengbo; Wang, Yajun; Feng, Qiliang; Wei, Ye; Ji, Jianlong; Zhang, Wendong

    2016-01-01

    The detection techniques used in biosensors can be broadly classified into label-based and label-free. Label-based detection relies on the specific properties of labels for detecting a particular target. In contrast, label-free detection is suitable for the target molecules that are not labeled or the screening of analytes which are not easy to tag. Also, more types of label-free biosensors have emerged with developments in biotechnology. The latest developed techniques in label-free biosensors, such as field-effect transistors-based biosensors including carbon nanotube field-effect transistor biosensors, graphene field-effect transistor biosensors and silicon nanowire field-effect transistor biosensors, magnetoelastic biosensors, optical-based biosensors, surface stress-based biosensors and other type of biosensors based on the nanotechnology are discussed. The sensing principles, configurations, sensing performance, applications, advantages and restriction of different label-free based biosensors are considered and discussed in this review. Most concepts included in this survey could certainly be applied to the development of this kind of biosensor in the future.

  13. Optical temperature sensing on flexible polymer foils

    NASA Astrophysics Data System (ADS)

    Sherman, Stanislav; Xiao, Yanfen; Hofmann, Meike; Schmidt, Thomas; Gleissner, Uwe; Zappe, Hans

    2016-04-01

    In contrast to established semiconductor waveguide-based or glass fiber-based integrated optical sensors, polymerbased optical systems offer tunable material properties, such as refractive index or viscosity, and thus provide additional degrees of freedom for sensor design and fabrication. Of particular interest in sensing applications are fully-integrated optical waveguide-based temperature sensors. These typically rely on Bragg gratings which induce a periodic refractive index variation in the waveguide so that a resonant wavelength of the structure is reflected.1,2 With broad-band excitation, a dip in the spectral output of the waveguide is thus generated at a precisely-defined wavelength. This resonant wavelength depends on the refractive index of the waveguide and the grating period, yet both of these quantities are temperature dependent by means of the thermo-optic effect (change in refractive index with temperature) and thermal expansion (change of the grating period with temperature). We show the design and fabrication of polymer waveguide-integrated temperature sensors based on Bragggratings, fabricated by replication technology on flexible PMMA foil substrates. The 175 μm thick foil serves as lower cladding for a polymeric waveguide fabricated from a custom-made UV-crosslinkable co-monomer composition. The fabrication of the grating structure includes a second replication step into a separate PMMA-foil. The dimensions of the Bragg-gratings are determined by simulations to set the bias point into the near infrared wavelength range, which allows Si-based detectors to be used. We present design considerations and performance data for the developed structures. The resulting sensor's signal is linear to temperature changes and shows a sensitivity of -306 nm/K, allowing high resolution temperature measurements.

  14. FIBER AND INTEGRATED OPTICS: Integrated optical passive ring resonator for optical gyroscopes

    NASA Astrophysics Data System (ADS)

    Baĭborodin, Yu V.; Dyadin, S. S.; Lyadenko, A. F.; Mashchenko, A. I.; Ul'yanov, I. A.; Fatin, Yu L.

    1992-02-01

    A passive ring resonator based on channel waveguides, formed in a K8 glass substrate by diffusion ion exchange in molten potassium nitrate, was made and investigated. The waveguide structure of the resonator included a ring waveguide as well as two Y-type couplers, whose symmetric arms were coupled to the ring waveguide, whereas homogeneous arms were coupled to an external laser and a photodetector. The coupling of the external devices to the channel waveguides was implemented by prisms and butt (end face) contacts. The transfer function of the ring resonator was determined experimentally in order to illustrate its resonant properties and sharpness. Estimates were obtained of the ultimate sensitivity of an optical gyroscope utilizing a ring resonator with the properties described above and ways of improving this sensitivity were analyzed.

  15. Process technologies of MPACVD planar waveguide devices and fiber attachment

    NASA Astrophysics Data System (ADS)

    Li, Cheng-Chung; Qian, Fan; Boudreau, Robert A.; Rowlette, John R., Sr.; Bowen, Terry P.

    1999-03-01

    Optical circuits based on low-loss glass waveguide on silicon are a practical and promising approach to integrate different functional components. Fiber attachment to planar waveguide provides a practical application for optical communications. Microwave Plasma Assisted Chemical Vapor Deposition (MPACVD) produces superior quality, low birefringence, low-loss, planar waveguides for integrated optical devices. Microwave plasma initiates the chemical vapor of SiCl4, GeCl4 and oxygen. A Ge-doped silica layer is thus deposited with a compatible high growth rate (i.e. 0.4 - 0.5 micrometer/min). Film properties are based on various parameters, such as chemical flow rates, chamber pressure and temperature, power level and injector design. The resultant refractive index can be varied between 1.46 (i.e. pure silica) and 1.60 (i.e. pure germania). Waveguides can be fabricated with any desired refractive index profile. Standard photolithography defines the waveguide pattern on a mask layer. The core layer is removed by plasma dry etch which has been investigated by both reactive ion etch (RIE) and inductively coupled plasma (ICP) etch. Etch rates of 3000 - 4000 angstrom/min have been achieved using ICP compared to typical etch rates of 200 - 300 angstrom/min using conventional RIE. Planar waveguides offer good mode matching to optical fiber. A polished fiber end can be glued to the end facet of waveguide with a very low optical coupling loss. In addition, anisotropic etching of silicon V- grooves provides a passive alignment capability. Epoxy and solder were used to fix the fiber within the guiding groove. Several designs of waveguide-fiber attachment will be discussed.

  16. Nanoscale Biosensor Based on Silicon Photonic Cavity for Home Healthcare Diagnostic Application

    NASA Astrophysics Data System (ADS)

    Ebrahimy, Mehdi N.; Moghaddam, Aydin B.; Andalib, Alireza; Naziri, Mohammad; Ronagh, Nazli

    2015-09-01

    In this paper, a new ultra-compact optical biosensor based on photonic crystal (phc) resonant cavity is proposed. This sensor has ability to work in chemical optical processes for the determination and analysis of liquid material. Here, we used an optical filter based on two-dimensional phc resonant cavity on a silicon layer and an active area is created in center of cavity. According to results, with increasing the refractive index of cavity, resonant wavelengths shift so that this phenomenon provides the ability to measure the properties of materials. This novel designed biosensor has more advantage to operate in the biochemical process for example sensing protein and DNA molecule refractive index. This nanoscale biosensor has quality factor higher than 1.5 × 104 and it is suitable to be used in the home healthcare diagnostic applications.

  17. Single-walled carbon nanotubes as near-infrared optical biosensors for life sciences and biomedicine.

    PubMed

    Jain, Astha; Homayoun, Aida; Bannister, Christopher W; Yum, Kyungsuk

    2015-03-01

    Single-walled carbon nanotubes that emit photostable near-infrared fluorescence have emerged as near-infrared optical biosensors for life sciences and biomedicine. Since the discovery of their near-infrared fluorescence, researchers have engineered single-walled carbon nanotubes to function as an optical biosensor that selectively modulates its fluorescence upon binding of target molecules. Here we review the recent advances in the single-walled carbon nanotube-based optical sensing technology for life sciences and biomedicine. We discuss the structure and optical properties of single-walled carbon nanotubes, the mechanisms for molecular recognition and signal transduction in single-walled carbon nanotube complexes, and the recent development of various single-walled carbon nanotube-based optical biosensors. We also discuss the opportunities and challenges to translate this emerging technology into biomedical research and clinical use, including the biological safety of single-walled carbon nanotubes. The advances in single-walled carbon nanotube-based near-infrared optical sensing technology open up a new avenue for in vitro and in vivo biosensing with high sensitivity and high spatial resolution, beneficial for many areas of life sciences and biomedicine. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Strong field localization in subwavelength metal-dielectric optical waveguides

    NASA Astrophysics Data System (ADS)

    Kozina, O. N.; Mel'Nikov, L. A.; Nefedov, I. S.

    2011-08-01

    Detailed calculations of eigenmodes of waveguiding structures made of silver and glass and containing coaxial cables with a nanoscale cross section of different configurations are conducted. In particular, the study focuses on optical coaxial waveguides with the core made in the form of a thin metallic cylinder filled with a dielectric. We show that these waveguides support relatively low-loss propagation of radiation that is strongly localized in the central region, has phase velocity approaching the speed of light and predominant electric-field orientation (dipole type). Optical characteristics of such waveguides are compared with those of coaxial-type waveguides containing a continuous central filament made of metal and with a multilayer structure. Using numeric modeling, we established that the proposed type of the waveguide enables the transmission of an optical image with relatively low losses with a submicron resolution over a distance considerably longer than its cross section. A typical propagation length in the waveguides based on silver and glass with the refractive index of about 1.5 at a wavelength of 500 nm is about 1700 nm.

  19. Optical Microfibre Based Photonic Components and Their Applications in Label-Free Biosensing

    PubMed Central

    Wang, Pengfei; Bo, Lin; Semenova, Yuliya; Farrell, Gerald; Brambilla, Gilberto

    2015-01-01

    Optical microfibre photonic components offer a variety of enabling properties, including large evanescent fields, flexibility, configurability, high confinement, robustness and compactness. These unique features have been exploited in a range of applications such as telecommunication, sensing, optical manipulation and high Q resonators. Optical microfibre biosensors, as a class of fibre optic biosensors which rely on small geometries to expose the evanescent field to interact with samples, have been widely investigated. Due to their unique properties, such as fast response, functionalization, strong confinement, configurability, flexibility, compact size, low cost, robustness, ease of miniaturization, large evanescent field and label-free operation, optical microfibres based biosensors seem a promising alternative to traditional immunological methods for biomolecule measurements. Unlabeled DNA and protein targets can be detected by monitoring the changes of various optical transduction mechanisms, such as refractive index, absorption and surface plasmon resonance, since a target molecule is capable of binding to an immobilized optical microfibre. In this review, we critically summarize accomplishments of past optical microfibre label-free biosensors, identify areas for future research and provide a detailed account of the studies conducted to date for biomolecules detection using optical microfibres. PMID:26287252

  20. Optical Microfibre Based Photonic Components and Their Applications in Label-Free Biosensing.

    PubMed

    Wang, Pengfei; Bo, Lin; Semenova, Yuliya; Farrell, Gerald; Brambilla, Gilberto

    2015-07-22

    Optical microfibre photonic components offer a variety of enabling properties, including large evanescent fields, flexibility, configurability, high confinement, robustness and compactness. These unique features have been exploited in a range of applications such as telecommunication, sensing, optical manipulation and high Q resonators. Optical microfibre biosensors, as a class of fibre optic biosensors which rely on small geometries to expose the evanescent field to interact with samples, have been widely investigated. Due to their unique properties, such as fast response, functionalization, strong confinement, configurability, flexibility, compact size, low cost, robustness, ease of miniaturization, large evanescent field and label-free operation, optical microfibres based biosensors seem a promising alternative to traditional immunological methods for biomolecule measurements. Unlabeled DNA and protein targets can be detected by monitoring the changes of various optical transduction mechanisms, such as refractive index, absorption and surface plasmon resonance, since a target molecule is capable of binding to an immobilized optical microfibre. In this review, we critically summarize accomplishments of past optical microfibre label-free biosensors, identify areas for future research and provide a detailed account of the studies conducted to date for biomolecules detection using optical microfibres.

  1. A double-taper optical fiber-based radiation wave other than evanescent wave in all-fiber immunofluorescence biosensor for quantitative detection of Escherichia coli O157:H7.

    PubMed

    Zhang, Zhonghuan; Hua, Fei; Liu, Ting; Zhao, Yong; Li, Jun; Yang, Ruifu; Yang, Changxi; Zhou, Lei

    2014-01-01

    Cylindrical or taper-and-cylinder combination optical fiber probe based on evanescent wave has been widely used for immunofluorescence biosensor to detect various analytes. In this study, in contrast to the contradiction between penetration depth and analyte diameter of optical fiber probe-based evanescent wave, we demonstrate that double-taper optical fiber used in a radiation wave-based all-fiber immunofluorescence biosensor (RWAIB) can detect micron-scale analytes using Escherichia coli O157:H7 as representative target. Finite-difference time-domain method was used to compare the properties of evanescent wave and radiation wave (RW). Ray-tracing model was formulated to optimize the taper geometry of the probe. Based on a commercial multi-mode fiber, a double-taper probe was fabricated and connected with biosensor through a "ferrule connector" optical fiber connector. The RWAIB configuration was accomplished using commercial multi-mode fibers and fiber-based devices according to the "all-fiber" method. The standard sample tests revealed that the sensitivity of the proposed technique for E. coli O157:H7 detection was 10(3) cfu · mL(-1). Quantitation could be achieved within the concentration range of 10(3) cfu · mL(-1) to 107 cfu · mL(-1). No non-specific recognition to ten kinds of food-borne pathogens was observed. The results demonstrated that based on the double-taper optical fiber RWAIB can be used for the quantitative detection of micron-scale targets, and RW sensing is an alternative for traditional evanescent wave sensing during the fabrication of fiber-optic biosensors.

  2. FIBER OPTIC BIOSENSOR FOR DNA DAMAGE

    EPA Science Inventory

    This paper describes a fiber optic biosensor for the rapid and sensitive detection of radiation-induced or chemically-induced oxidative DNA damage. The assay is based on the hybridization and temperature-induced dissociation (melting curves) of synthetic oligonucleotides. The...

  3. Design of a hybrid As₂S₃-Ti:LiNbO₃ optical waveguide for phase-matched difference frequency generation at mid-infrared.

    PubMed

    Wang, Xin; Madsen, Christi K

    2014-11-03

    Based on arsenic tri-sulfide films on titanium-diffused lithium niobate, we designed a hybrid optical waveguide for efficient mid-infrared emission by phase-matched difference frequency generation (DFG). The hybrid waveguide structure possesses a low-index magnesium fluoride buffer layer sandwiched between two high-index As(2)S(3) slabs, so that pump and signal waves are tightly confined by titanium-diffused waveguide while the DFG output idler wave at mid-infrared is confined by the whole hybrid waveguide structure. On a 1 mm-long hybrid waveguide pumped at 50 mW powers, a normalized power conversion efficiency of 20.52%W(-1)cm(-2) was theoretically predicted, which is the highest record for mid-infrared DFG waveguides based on lithium niobate crystal, to the best of our knowledge. Using a tunable near-infrared pump laser at 1.38-1.47 µm or a tunable signal laser at 1.95-2.15 µm, a broad mid-infrared tuning range from 4.0 µm to 4.9 µm can be achieved. Such hybrid optical waveguides are feasible for mid-infrared emission with mW powers and sub-nanometer linewidths.

  4. All optical controlled photonic integrated circuits using azo dye functionized sol-gel material

    NASA Astrophysics Data System (ADS)

    Ke, Xianjun

    The main focus of this dissertation is development and characterization of all-optical controllable azo dye functionized sol gel material, demonstrating a PIC fabrication technique on glass substrate using such material, and exploration and feasibility demonstration of three PIC functional devices namely optical variable attenuator, optical switches, and optical tunable filters using the material. The realization of all the devices in this dissertation are based on one material: dye functionalized sol-gel material. A photochromic sol-gel material functionalized with azo dye was synthesized and characterized. It possesses a photochromic characteristic under the control of green laser beam illumination. The material characteristics suggest the possibility of a new promising material platform candidate for the fabrication of alloptical controlled photonic integrated circuits. As the first potential application of the dye functionalized sol-gel material, an alloptical variable attenuator was designed and demonstrated. The optical variable attenuation is achieved in Mach-Zehnder interferometric configuration through all-optical modulation of sol-gel waveguide phase shifters. A 2 x 2 optical switch based on multimode interference (MMI) waveguide structure is proposed in the dissertation. The schematic configuration of the optical switch consists of a cascade of two identical MMIs with two all-optical controlled phase shifters realized by using the photochromic sol-gel material. The cross or bar switch state of the optical switch is determined by the phase difference between the two sol-gel waveguide phase shifters. An all-optical tunable filter is designed and its feasibility demonstrated by using the sol-gel photochromic material. Except for the phase change demonstrated on sol-gel waveguide phase shifters, dynamic gratings were observed on sol-gel film when exposed to two interference beams. This reveals the possibility of realizing Bragg grating-based tunable filters. The schematic configuration of proposed tunable filters consists of a single straight waveguide embedded with a sol-gel waveguide. The wavelength tuning of the tunable filters is accomplished by varying the grating period.

  5. Compound semiconductor optical waveguide switch

    DOEpatents

    Spahn, Olga B.; Sullivan, Charles T.; Garcia, Ernest J.

    2003-06-10

    An optical waveguide switch is disclosed which is formed from III-V compound semiconductors and which has a moveable optical waveguide with a cantilevered portion that can be bent laterally by an integral electrostatic actuator to route an optical signal (i.e. light) between the moveable optical waveguide and one of a plurality of fixed optical waveguides. A plurality of optical waveguide switches can be formed on a common substrate and interconnected to form an optical switching network.

  6. Roughness measurements on coupling structures for optical interconnections integrated on a printed circuit board

    NASA Astrophysics Data System (ADS)

    Hendrickx, Nina; Van Erps, Jürgen; Suyal, Himanshu; Taghizadeh, Mohammad; Thienpont, Hugo; Van Daele, Peter

    2006-04-01

    In this paper, laser ablation (at UGent), deep proton writing (at VUB) and laser direct writing (at HWU) are presented as versatile technologies that can be used for the fabrication of coupling structures for optical interconnections integrated on a printed circuit board (PCB). The optical layer, a highly cross-linked acrylate based polymer, is applied on an FR4 substrate. Both laser ablation and laser direct writing are used for the definition of arrays of multimode optical waveguides, which guide the light in the plane of the optical layer. In order to couple light vertically in/out of the plane of the optical waveguides, coupling structures have to be integrated into the optical layer. Out-of-plane turning mirrors, that deflect the light beam over 90°, are used for this purpose. The surface roughness and angle of three mirror configurations are evaluated: a laser ablated one that is integrated into the optical waveguide, a laser direct written one that is also directly written onto the waveguide and a DPW insert that is plugged into a cavity into the waveguiding layer.

  7. Fiber optic-based biosensor

    NASA Technical Reports Server (NTRS)

    Ligler, Frances S.

    1991-01-01

    The NRL fiber optic biosensor is a device which measures the formation of a fluorescent complex at the surface of an optical fiber. Antibodies and DNA binding proteins provide the mechanism for recognizing an analyze and immobilizing a fluorescent complex on the fiber surface. The fiber optic biosensor is fast, sensitive, and permits analysis of hazardous materials remote from the instrumentation. The fiber optic biosensor is described in terms of the device configuration, chemistry for protein immobilization, and assay development. A lab version is being used for assay development and performance characterization while a portable device is under development. Antibodies coated on the fiber are stable for up to two years of storage prior to use. The fiber optic biosensor was used to measure concentration of toxins in the parts per billion (ng/ml) range in under a minute. Immunoassays for small molecules and whole bacteria are under development. Assays using DNA probes as the detection element can also be used with the fiber optic sensor, which is currently being developed to detect biological warfare agents, explosives, pathogens, and toxic materials which pollute the environment.

  8. Optical waveguide device with an adiabatically-varying width

    DOEpatents

    Watts,; Michael R. , Nielson; Gregory, N [Albuquerque, NM

    2011-05-10

    Optical waveguide devices are disclosed which utilize an optical waveguide having a waveguide bend therein with a width that varies adiabatically between a minimum value and a maximum value of the width. One or more connecting members can be attached to the waveguide bend near the maximum value of the width thereof to support the waveguide bend or to supply electrical power to an impurity-doped region located within the waveguide bend near the maximum value of the width. The impurity-doped region can form an electrical heater or a semiconductor junction which can be activated with a voltage to provide a variable optical path length in the optical waveguide. The optical waveguide devices can be used to form a tunable interferometer (e.g. a Mach-Zehnder interferometer) which can be used for optical modulation or switching. The optical waveguide devices can also be used to form an optical delay line.

  9. Fabrication and demonstration of 1 × 8 silicon-silica multi-chip switch based on optical phased array

    NASA Astrophysics Data System (ADS)

    Katayose, Satomi; Hashizume, Yasuaki; Itoh, Mikitaka

    2016-08-01

    We experimentally demonstrated a 1 × 8 silicon-silica hybrid thermo-optic switch based on an optical phased array using a multi-chip integration technique. The switch consists of a silicon chip with optical phase shifters and two silica-based planar lightwave circuit (PLC) chips composed of optical couplers and fiber connections. We adopted a rib waveguide as the silicon waveguide to reduce the coupling loss and increase the alignment tolerance for coupling between silicon and silica waveguides. As a result, we achieved a fast switching response of 81 µs, a high extinction ratio of over 18 dB and a low insertion loss of 4.9-8.1 dB including a silicon-silica coupling loss of 0.5 ± 0.3 dB at a wavelength of 1.55 µm.

  10. Optical Waveguides Written in Silicon with Femtosecond Laser

    NASA Astrophysics Data System (ADS)

    Pavlov, Ihor; Tokel, Onur; Pavlova, Svitlana; Kadan, Viktor; Makey, Ghaith; Turnali, Ahmed; Ilday, Omer

    Silicon is one of the most widely used materials in modern technology, ranging from electronics and Si-photonics to microfluidic and sensor applications. Despite the long history of Si-based devices, and the strong demand for opto-electronical integration, 3D Si laser processing technology is still challenging. Recently, nanosecond-pulsed laser was used to fabricate embedded holographic elements in Si. However, until now, there was no demonstration of femtosecond-laser-written optical elements inside Si. In this paper, we present optical waveguides written deep inside Si with 1.5 um femtosecond laser. The laser beam, with 2 uJ pulse energy and 350 fs pulse duration focused inside Si sample, produces permanent modification of Si. By moving the lens along the beam direction we were able to produce optical waveguides up to 5 mm long. The diameter of the waveguide is measured to be 10 um. The waveguides were characterized with both optical shadowgraphy and far field imaging after CW light coupling. We observed nearly single mode propagation of light inside of the waveguide. The obtained difference of refractive index inside of the waveguide, is 2.5*10-4. TUBITAK Grant 113M930, TUBITAK Grant 114F256.

  11. Integrated optical isolators using magnetic surface plasmon (Presentation Recording)

    NASA Astrophysics Data System (ADS)

    Shimizu, Hiromasa; Kaihara, Terunori; Umetsu, Saori; Hosoda, Masashi

    2015-09-01

    Optical isolators are one of the essential components to protect semiconductor laser diodes (LDs) from backward reflected light in integrated optics. In order to realize optical isolators, nonreciprocal propagation of light is necessary, which can be realized by magnetic materials. Semiconductor optical isolators have been strongly desired on Si and III/V waveguides. We have developed semiconductor optical isolators based on nonreciprocal loss owing to transverse magneto-optic Kerr effect, where the ferromagnetic metals are deposited on semiconductor optical waveguides1). Use of surface plasmon polariton at the interface of ferromagnetic metal and insulator leads to stronger optical confinement and magneto-optic effect. It is possible to modulate the optical confinement by changing the magnetic field direction, thus optical isolator operation is proposed2, 3). We have investigated surface plasmons at the interfaces between ferrimagnetic garnet/gold film, and applications to waveguide optical isolators. We assumed waveguides composed of Au/Si(38.63nm)/Ce:YIG(1700nm)/Si(220nm)/Si , and calculated the coupling lengths between Au/Si(38.63nm)/Ce:YIG plasmonic waveguide and Ce:YIG/Si(220nm)/Si waveguide for transversely magnetized Ce:YIG with forward and backward directions. The coupling length was calculated to 232.1um for backward propagating light. On the other hand, the coupling was not complete, and the length was calculated to 175.5um. The optical isolation by using the nonreciprocal coupling and propagation loss was calculated to be 43.7dB when the length of plasmonic waveguide is 700um. 1) H. Shimizu et al., J. Lightwave Technol. 24, 38 (2006). 2) V. Zayets et al., Materials, 5, 857-871 (2012). 3) J. Montoya, et al, J. Appl. Phys. 106, 023108, (2009).

  12. Love-Wave Biosensors Using Cross-Linked Polymer Waveguides on LiTaO{sub 3} Substrates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BENDER,FLORIAN; CERNOSEK,RICHARD W.; JOSSE,F.

    The design and performance of Love-wave sensors using cross-linked poly-(methyl methacrylate) waveguides of thickness of 0.3--3.2 {micro}m on LiTaO{sub 3} substrates are described. It is found that this layer-substrate combination provides sufficient waveguidance, and electrical isolation of the IDTs from the liquid environment to achieve low acoustic loss and distortion. In bio-sensing experiments, mass sensitivity up to 1,420 Hz/(ng/mm{sup 2}) is demonstrated.

  13. Gain determination of optical active doped planar waveguides

    NASA Astrophysics Data System (ADS)

    Šmejcký, J.; Jeřábek, V.; Nekvindová, P.

    2017-12-01

    This paper summarizes the results of the gain transmission characteristics measurement carried out on the new ion exchange Ag+ - Na+ optical Er3+ and Yb3+ doped active planar waveguides realized on a silica based glass substrates. The results were used for optimization of the precursor concentration in the glass substrates. The gain measurements were performed by the time domain method using a pulse generator, as well as broadband measurement method using supercontinuum optical source in the wavelength domain. Both methods were compared and the results were graphically processed. It has been confirmed that pulse method is useful as it provides a very accurate measurement of the gain - pumping power characteristics for one wavelength. In the case of radiation spectral characteristics, our measurement exactly determined the maximum gain wavelength bandwidth of the active waveguide. The spectral characteristics of the pumped and unpumped waveguides were compared. The gain parameters of the reported silica-based glasses can be compared with the phosphate-based parameters, typically used for optical active devices application.

  14. Low-loss multimode interference couplers for terahertz waves

    NASA Astrophysics Data System (ADS)

    Themistos, Christos; Kalli, Kyriacos; Komodromos, Michael; Markides, Christos; Quadir, Anita; Rahman, B. M. Azizur; Grattan, Kenneth T. V.

    2012-04-01

    The terahertz (THz) frequency region of the electromagnetic spectrum is located between the traditional microwave spectrum and the optical frequencies, and offers a significant scientific and technological potential in many fields, such as in sensing, in imaging and in spectroscopy. Waveguiding in this intermediate spectral region is a major challenge. Amongst the various THz waveguides suggested, metal-clad plasmonic waveguides and specifically hollow core structures, coated with insulating material are the most promising low-loss waveguides used in both active and passive devices. Optical power splitters are important components in the design of optoelectronic systems and optical communication networks such as Mach-Zehnder Interferometric switches, polarization splitter and polarization scramblers. Several designs for the implementation of the 3dB power splitters have been proposed in the past, such as the directional coupler-based approach, the Y-junction-based devices and the MMI-based approach. In the present paper a novel MMI-based 3dB THz wave splitter is implemented using Gold/polystyrene (PS) coated hollow glass rectangular waveguides. The H-field FEM based full-vector formulation is used here to calculate the complex propagation characteristics of the waveguide structure and the finite element beam propagation method (FE-BPM) and finite difference time domain (FDTD) approach to demonstrate the performance of the proposed 3dB splitter.

  15. Nanoassembled dynamic optical waveguides and sensors based on zeolite L nanocontainers

    NASA Astrophysics Data System (ADS)

    Barroso, Álvaro; Dieckmann, Katrin; Alpmann, Christina; Buscher, Tim; Studer, Armido; Denz, Cornelia

    2015-03-01

    Although optical functional devices as waveguides and sensors are of utmost importance for metrology on the nano scale, the micro-and nano-assembly by optical means of functional materials to create such optical elements has yet not been considered. In the last years, an elegant strategy based on holographic optical tweezers (HOT) has been developed to design and fabricate permanent and dynamic three-dimensional micro- and nanostructures based on functional nanocontainers as building blocks. Nanocontainers that exhibit stable and ordered voids to hierarchically organize guest materials are especially attractive. Zeolite L are a type of porous micro-sized crystals which features a high number of strictly one-dimensional, parallel aligned nanochannels. They are highly interesting as building blocks of functional nano-and microsystems due to their potential as nanocontainers to accommodate various different guest molecules and to assemble them in specific configurations. For instance, based on zeolite L crystals, microscopic polarization sensors and chains of several microcrystals for hierarchical supramolecular organization have been realized. Here, we demonstrate the ability of nanocontainers in general, and zeolite L crystals in particular to represent the basic constituent of optical functional microsystems. We show that the capability of HOT to manipulate multitude of non-spherical microparticles in three dimensions can be exploited for the investigation of zeolite L nanocontainers as dynamic optical waveguides. Moreover, we implement as additional elements dye-loaded zeolite L to sense the guiding features of these novel waveguides with high spatial precision and microspheres to enhance the light coupling into the zeolite L waveguides. With this elaborated approach of using nanocontainers as tailored building blocks for functional optical systems a new era of bricking optical components in a lego-like style becomes feasible.

  16. Nano-optical conveyor belt with waveguide-coupled excitation.

    PubMed

    Wang, Guanghui; Ying, Zhoufeng; Ho, Ho-pui; Huang, Ying; Zou, Ningmu; Zhang, Xuping

    2016-02-01

    We propose a plasmonic nano-optical conveyor belt for peristaltic transport of nano-particles. Instead of illumination from the top, waveguide-coupled excitation is used for trapping particles with a higher degree of precision and flexibility. Graded nano-rods with individual dimensions coded to have resonance at specific wavelengths are incorporated along the waveguide in order to produce spatially addressable hot spots. Consequently, by switching the excitation wavelength sequentially, particles can be transported to adjacent optical traps along the waveguide. The feasibility of this design is analyzed using three-dimensional finite-difference time-domain and Maxwell stress tensor methods. Simulation results show that this system is capable of exciting addressable traps and moving particles in a peristaltic fashion with tens of nanometers resolution. It is the first, to the best of our knowledge, report about a nano-optical conveyor belt with waveguide-coupled excitation, which is very important for scalability and on-chip integration. The proposed approach offers a new design direction for integrated waveguide-based optical manipulation devices and its application in large scale lab-on-a-chip integration.

  17. Optical waveguide loop for planar trapping of blood cells and microspheres

    NASA Astrophysics Data System (ADS)

    Ahluwalia, Balpreet S.; Hellesø, Olav G.

    2013-09-01

    The evanescent field from a waveguide can be used to trap and propel a particle. An optical waveguide loop with an intentional gap at the center is used for planar transport and stable trapping of particles. The waveguide acts as a conveyor belt to trap and deliver spheres towards the gap. At the gap, the counter-diverging light fields hold the sphere at a fixed position. Numerical simulation based on the finite element method was performed in three dimensions using a computer cluster. The field distribution and optical forces for rib and strip waveguide designs are compared and discussed. The optical force on a single particle was computed for various positions of the particle in the gap. Simulation predicted stable trapping of particles in the gap. Depending on the gap separation (2-50 μm) a single or multiple spheres and red blood cells were trapped at the gap. Waveguides were made of tantalum pentaoxide material. The waveguides are only 180 nm thick and thus could be integrated with other functions on the chip.

  18. Optimization of figure of merit in magnetoplasmonic waveguides with Fe/Au multilayer for optical isolator based on nonreciprocal coupling on Si waveguides

    NASA Astrophysics Data System (ADS)

    Shimizu, Hiromasa; Shimodaira, Takahiro

    2018-04-01

    We report on magnetoplasmonic Si waveguides with a ferromagnetic Fe/conductive metal Au multilayer for realizing a sizable magnetooptic effect with a low propagation loss for integrated optical isolators. By combining the ferromagnetic metal Fe with a highly conductive Au layer, the largest nonreciprocal differences in effective index were estimated for propagation lengths of 1-20 µm. Mode analysis with and without a Au layer clarified that the insertion of a Au layer on an Fe layer improves the optical confinement in the Fe layer with reduced propagation loss and is effective in enlarging the magnetooptic effect for the same propagation length. On the basis of the optimized Fe/Au multilayer structure, we designed waveguide optical isolators based on nonreciprocal coupling by the finite difference time domain (FDTD) method. We estimated an optical isolation of 10.8 dB with a forward insertion loss of 13.4 dB in a 34-µm-long nonreciprocal directional coupler.

  19. Graphene oxide-based optical biosensor functionalized with peptides for explosive detection.

    PubMed

    Zhang, Qian; Zhang, Diming; Lu, Yanli; Yao, Yao; Li, Shuang; Liu, Qingjun

    2015-06-15

    A label-free optical biosensor was constructed with biofunctionalized graphene oxide (GO) for specific detection of 2,4,6-trinitrotoluene (TNT). By chemically binding TNT-specific peptides with GO, the biosensor gained unique optoelectronic properties and high biological sensitivity, with transducing bimolecular bonding into optical signals. Through UV absorption detection, increasing absorbance responses could be observed in presence of TNT at different concentrations, as low as 4.40×10(-9) mM, and showed dose-dependence and stable behavior. Specific responses of the biosensor were verified with the corporation of 2,6-dinitrotoluene (DNT), which had similar molecular structure to TNT. Thus, with high sensitivity and selectivity, the biosensor provided a convenient approach for detection of explosives as miniaturizing and integrating devices. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Dimension-sensitive optical responses of electromagnetically induced transparency vapor in a waveguide

    NASA Astrophysics Data System (ADS)

    Qi Shen, Jian; He, Sailing

    2006-12-01

    A three-level EIT (electromagnetically induced transparency) vapor is used to manipulate the transparency and absorption properties of the probe light in a waveguide. The most remarkable feature of the present scheme is such that the optical responses resulting from both electromagnetically induced transparency and large spontaneous emission enhancement are very sensitive to the frequency detunings of the probe light as well as to the small changes of the waveguide dimension. The potential applications of the dimension- and dispersion-sensitive EIT responses are discussed, and the sensitivity limits of some waveguide-based sensors, including electric absorption modulator, optical switch, wavelength sensor, and sensitive magnetometer, are analyzed.

  1. Detection of low levels of Listeria monocytogenes cells by using a fiber-optic immunosensor.

    PubMed

    Geng, Tao; Morgan, Mark T; Bhunia, Arun K

    2004-10-01

    Biosensor technology has a great potential to meet the need for sensitive and nearly real-time microbial detection from foods. An antibody-based fiber-optic biosensor to detect low levels of Listeria monocytogenes cells following an enrichment step was developed. The principle of the sensor is a sandwich immunoassay where a rabbit polyclonal antibody was first immobilized on polystyrene fiber waveguides through a biotin-streptavidin reaction to capture Listeria cells on the fiber. Capture of cells on the fibers was confirmed by scanning electron microscopy. A cyanine 5-labeled murine monoclonal antibody, C11E9, was used to generate a specific fluorescent signal, which was acquired by launching a 635-nm laser light from an Analyte 2000 and collected by a photodetector at 670 to 710 nm. This immunosensor was specific for L. monocytogenes and showed a significantly higher signal strength than for other Listeria species or other microorganisms, including Escherichia coli, Enterococcus faecalis, Salmonella enterica, Lactobacillus plantarum, Carnobacterium gallinarum, Hafnia alvei, Corynebacterium glutamicum, Enterobacter aerogenes, Pseudomonas aeruginosa, and Serratia marcescens, in pure or in mixed-culture setup. Fiber-optic results could be obtained within 2.5 h of sampling. The sensitivity threshold was about 4.3 x 10(3) CFU/ml for a pure culture of L. monocytogenes grown at 37 degrees C. When L. monocytogenes was mixed with lactic acid bacteria or grown at 10 degrees C with 3.5% NaCl, the detection threshold was 4.1 x 10(4) or 2.8 x 10(7) CFU/ml, respectively. In less than 24 h, this method could detect L. monocytogenes in hot dog or bologna naturally contaminated or artificially inoculated with 10 to 1,000 CFU/g after enrichment in buffered Listeria enrichment broth.

  2. Design of a compact static Fourier transform spectrometer in integrated optics based on a leaky loop structure.

    PubMed

    Martin, Bruno; Morand, Alain; Benech, Pierre; Leblond, Gregory; Blaize, Sylvain; Lerondel, Gilles; Royer, Pascal; Kern, Pierre; Le Coarer, Etienne

    2009-01-15

    A compact static Fourier transform spectrometer for integrated optics is proposed. It is based on a plane leaky loop structure combined with a plane waveguide. The interference pattern produced in the loop structure leaks outside of it and is guided in the plane waveguide to the photodetector array. This configuration allows one to control the shape of the field pattern at the end of the plane waveguide. A large fringe pattern with a high interference fringe contrast is obtained. A two-dimensional model based on an aperiodic Fourier modal method is used to modelize the coupling between the bent and the plane waveguides, completed with the Helmholtz-Kirchhoff propagation. This concept gives access to plan and compact spectrometers requiring only a single low-cost realization process step. The simulation has been done to realize a spectrometer in glass integrated optics (Deltalambda=6.1 nm at 1500 nm).

  3. Design and investigation of properties of nanocrystalline diamond optical planar waveguides.

    PubMed

    Prajzler, Vaclav; Varga, Marian; Nekvindova, Pavla; Remes, Zdenek; Kromka, Alexander

    2013-04-08

    Diamond thin films have remarkable properties comparable with natural diamond. Because of these properties it is a very promising material for many various applications (sensors, heat sink, optical mirrors, chemical and radiation wear, cold cathodes, tissue engineering, etc.) In this paper we report about design, deposition and measurement of properties of optical planar waveguides fabricated from nanocrystalline diamond thin films. The nanocrystalline diamond planar waveguide was deposited by microwave plasma enhanced chemical vapor deposition and the structure of the deposited film was studied by scanning electron microscopy and Raman spectroscopy. The design of the presented planar waveguides was realized on the bases of modified dispersion equation and was schemed for 632.8 nm, 964 nm, 1 310 nm and 1 550 nm wavelengths. Waveguiding properties were examined by prism coupling technique and it was found that the diamond based planar optical element guided one fundamental mode for all measured wavelengths. Values of the refractive indices of our NCD thin film measured at various wavelengths were almost the same as those of natural diamond.

  4. Optical biosensor with poly[N-nonyl-3,6-bis(ethylenedioxythiophene)carbazole] matrix for monitoring of phenol derivatives

    NASA Astrophysics Data System (ADS)

    Jedrychowska, Agnieszka; Malecha, Karol; Cabaj, Joanna; Sołoducho, Jadwiga

    2014-08-01

    The aim of the research was to develop an enzymatic, optical biosensor which provides quick and convenient determination of phenolic compounds in aqueous solutions. The biosensing strategy concerns design, fabrication and testing of a miniature ceramic-based biosensor which is destined for in-situ substrate monitoring. The base of the measuring system was fabricated using low temperature co-fired ceramics (LTCC) technology. The biocatalyst - laccase- was immobilized on the thin film of poly[N-nonyl-3,6-bis(ethylenedioxythiophene)carbazole] which provided good binding of the enzyme to the substrate and positively affected on the catalytic activity of the protein. In order to evaluate properties of the designed biosensor, its response for various concentrations of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diamonnium sal (ABTS) was measured. The optical biosensor produced by presented method could find applications in many fields, i.e. for detection of phenolic compounds in food products and beverages, in industry for control of technological processes or for environmental monitoring

  5. Electrically driven hybrid Si/III-V Fabry-Pérot lasers based on adiabatic mode transformers.

    PubMed

    Ben Bakir, B; Descos, A; Olivier, N; Bordel, D; Grosse, P; Augendre, E; Fulbert, L; Fedeli, J M

    2011-05-23

    We report the first demonstration of an electrically driven hybrid silicon/III-V laser based on adiabatic mode transformers. The hybrid structure is formed by two vertically superimposed waveguides separated by a 100-nm-thick SiO2 layer. The top waveguide, fabricated in an InP/InGaAsP-based heterostructure, serves to provide optical gain. The bottom Si-waveguides system, which supports all optical functions, is constituted by two tapered rib-waveguides (mode transformers), two distributed Bragg reflectors (DBRs) and a surface-grating coupler. The supermodes of this hybrid structure are controlled by an appropriate design of the tapers located at the edges of the gain region. In the middle part of the device almost all the field resides in the III-V waveguide so that the optical mode experiences maximal gain, while in regions near the III-V facets, mode transformers ensure an efficient transfer of the power flow towards Si-waveguides. The investigated device operates under quasi-continuous wave regime. The room temperature threshold current is 100 mA, the side-mode suppression ratio is as high as 20 dB, and the fiber-coupled output power is ~7 mW.

  6. System and method for ultrafast optical signal detecting via a synchronously coupled anamorphic light pulse encoded laterally

    DOEpatents

    Heebner, John E [Livermore, CA

    2010-08-03

    In one general embodiment, a method for ultrafast optical signal detecting is provided. In operation, a first optical input signal is propagated through a first wave guiding layer of a waveguide. Additionally, a second optical input signal is propagated through a second wave guiding layer of the waveguide. Furthermore, an optical control signal is applied to a top of the waveguide, the optical control signal being oriented diagonally relative to the top of the waveguide such that the application is used to influence at least a portion of the first optical input signal propagating through the first wave guiding layer of the waveguide. In addition, the first and the second optical input signals output from the waveguide are combined. Further, the combined optical signals output from the waveguide are detected. In another general embodiment, a system for ultrafast optical signal recording is provided comprising a waveguide including a plurality of wave guiding layers, an optical control source positioned to propagate an optical control signal towards the waveguide in a diagonal orientation relative to a top of the waveguide, at least one optical input source positioned to input an optical input signal into at least a first and a second wave guiding layer of the waveguide, and a detector for detecting at least one interference pattern output from the waveguide, where at least one of the interference patterns results from a combination of the optical input signals input into the first and the second wave guiding layer. Furthermore, propagation of the optical control signal is used to influence at least a portion of the optical input signal propagating through the first wave guiding layer of the waveguide.

  7. Integrated-optic current sensors with a multimode interference waveguide device.

    PubMed

    Kim, Sung-Moon; Chu, Woo-Sung; Kim, Sang-Guk; Oh, Min-Cheol

    2016-04-04

    Optical current sensors based on polarization-rotated reflection interferometry are demonstrated using polymeric integrated optics and various functional optical waveguide devices. Interferometric sensors normally require bias feedback control for maintaining the operating point, which increases the cost. In order to resolve this constraint of feedback control, a multimode interference (MMI) waveguide device is integrated onto the current-sensor optical chip in this work. From the multiple outputs of the MMI, a 90° phase-shifted transfer function is obtained. Using passive quadrature demodulation, we demonstrate that the sensor could maintain the output signal regardless of the drift in the operating bias-point.

  8. Recent Advances in Micro-/Nanostructured Metal-Organic Frameworks towards Photonic and Electronic Applications.

    PubMed

    Yang, Xiaogang; Lin, Xianqing; Zhao, Yong Sheng; Yan, Dongpeng

    2018-05-02

    Micro- and nanometer-sized metal-organic frameworks (MOFs) materials have attracted great attention due to their unique properties and various potential applications in photonics, electronics, high-density storage, chemo-, and biosensors. The study of these materials supplies insight into how the crystal structure, molecular components, and micro-/nanoscale effects can influence the performance of inorganic-organic hybrid materials. In this Minireview article, we introduce recent breakthroughs in the controlled synthesis of MOF micro-/nanomaterials with specific structures and compositions, the tunable photonic and electronic properties of which would provide a novel platform for multifunctional applications. Firstly, the design strategies for MOFs based on self-assembly and crystal engineering principles are introduced. Attention is then focused on the methods of fabrication of low-dimensional MOF micro-/nanostructures. Their new applications including two-photon excited fluorescence, multi-photon pumped lasing, optical waveguides, nonlinear optical (NLO), and field-effect transistors are also outlined. Finally, we briefly discuss perspectives on the further development of these hybrid crystalline micro-/nanomaterials. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Large-core single-mode rib SU8 waveguide using solvent-assisted microcontact molding.

    PubMed

    Huang, Cheng-Sheng; Wang, Wei-Chih

    2008-09-01

    This paper describes a novel fabrication technique for constructing a polymer-based large-core single-mode rib waveguide. A negative tone SU8 photoresist with a high optical transmission over a large wavelength range and stable mechanical properties was used as a waveguide material. A waveguide was constructed by using a polydimethylsiloxane stamp combined with a solvent-assisted microcontact molding technique. The effects on the final pattern's geometry of four different process conditions were investigated. Optical simulations were performed using beam propagation method software. Single-mode beam propagation was observed at the output of the simulated waveguide as well as the actual waveguide through the microscope image.

  10. Waveguide metatronics: Lumped circuitry based on structural dispersion.

    PubMed

    Li, Yue; Liberal, Iñigo; Della Giovampaola, Cristian; Engheta, Nader

    2016-06-01

    Engineering optical nanocircuits by exploiting modularization concepts and methods inherited from electronics may lead to multiple innovations in optical information processing at the nanoscale. We introduce the concept of "waveguide metatronics," an advanced form of optical metatronics that uses structural dispersion in waveguides to obtain the materials and structures required to construct this class of circuitry. Using numerical simulations, we demonstrate that the design of a metatronic circuit can be carried out by using a waveguide filled with materials with positive permittivity. This includes the implementation of all "lumped" circuit elements and their assembly in a single circuit board. In doing so, we extend the concepts of optical metatronics to frequency ranges where there are no natural plasmonic materials available. The proposed methodology could be exploited as a platform to experimentally validate optical metatronic circuits in other frequency regimes, such as microwave frequency setups, and/or to provide a new route to design optical nanocircuitry.

  11. Comparative determination of two probiotics by QCM and OWLS-based immunosensors.

    PubMed

    Szalontai, Helga; Adányi, Nóra; Kiss, Attila

    2014-09-25

    The regular consumption of foods containing probiotic bacteria has beneficial physiological effects on the health and the digestion system. There is a need for novel analytical approaches for the determination of these bacteria that are faster than the classical plate counting method. For this purpose, two label-free biosensors were investigated and presented in this paper: Quartz Crystal Microbalance (QCM) and Optical Waveguide Lightmode Spectroscopy (OWLS) based direct immunosensors were developed for real-time direct detection of probiotic bacteria in fermented dairy products. Bifidobacterium bifidum O1356 and Lactobacillus acidophilus O1132 were detected by polyclonal anti-B. bifidum IgG and anti-L. acidophilus IgG immobilized on the sensors' surface. Sulfo-LC-SPDP cross linking agent was used to bind antibodies to the gold surface of the QCM's AT-cut quartz wafer. Concerning OWLS, antibodies were covalently bound to the amino groups of the silanized surface of the waveguide by glutaraldehyde. The dynamic measuring range was found between 1.0E+3 and 5.0E+5CFUmL(-1) in 100 fold diluted fermented milk products by QCM and with OWLS. Considering the current legislation of the probiotic content in probiotic products, the two developed immunosensors can be applied for rapid quantification of L. acidophilus and B. bifidum in fermented milk. These examinations offer effective alternatives to the microbiological plate counting method. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Perforated hollow-core optical waveguides for on-chip atomic spectroscopy and gas sensing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Giraud-Carrier, M., E-mail: mgeecee@byu.edu; Hill, C.; Decker, T.

    2016-03-28

    A hollow-core waveguide structure for on-chip atomic spectroscopy is presented. The devices are based on Anti-Resonant Reflecting Optical Waveguides and may be used for a wide variety of applications which rely on the interaction of light with gases and vapors. The designs presented here feature short delivery paths of the atomic vapor into the hollow waveguide. They also have excellent environmental stability by incorporating buried solid-core waveguides to deliver light to the hollow cores. Completed chips were packaged with an Rb source and the F = 3 ≥ F′ = 2, 3, 4 transitions of the D2 line in {sup 85}Rb were monitored formore » optical absorption. Maximum absorption peak depths of 9% were measured.« less

  13. A low-cost photonic biosensor built on a polymer platform

    NASA Astrophysics Data System (ADS)

    Wang, Linghua; Kodeck, Valérie; Van Vlierberghe, Sandra; Ren, Jun; Teng, Jie; Han, Xiuyou; Jian, Xigao; Baets, Roel; Morthier, Geert; Zhao, Mingshan

    2011-12-01

    Planar integrated optical biosensors are becoming more and more important as they facilitate label-free and real time monitoring biosensing with high sensitivity. In this paper, the systematic research on one kind of optical biosensor, based on a resonant principle in a polymer ring resonator, will be presented. Reduced footprint and high sensitivity are advantages of this kind of biosensor. Rather than expensive CMOS fabrication, the device with high performance is fabricated through a simple UV based soft imprint technique utilizing self-developed low loss polymer material. The measurement results for the bulk sensing of a NaCl solution and the surface sensing of a minimal amount of avidin molecules in a buffered solution will be presented.

  14. Microfabricated Waveguide Atom Traps.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jau, Yuan-Yu

    A nanoscale , microfabricated waveguide structure can in - principle be used to trap atoms in well - defined locations and enable strong photon-atom interactions . A neutral - atom platform based on this microfabrication technology will be prealigned , which is especially important for quantum - control applications. At present, there is still no reported demonstration of evanescent - field atom trapping using a microfabricated waveguide structure. We described the capabilities established by our team for future development of the waveguide atom - trapping technology at SNL and report our studies to overcome the technical challenges of loading coldmore » atoms into the waveguide atom traps, efficient and broadband optical coupling to a waveguide, and the waveguide material for high - power optical transmission. From the atomic - physics and the waveguide modeling, w e have shown that a square nano-waveguide can be utilized t o achieve better atomic spin squeezing than using a nanofiber for first time.« less

  15. Tunable slow light in graphene-based hyperbolic metamaterial waveguide operating in SCLU telecom bands.

    PubMed

    Tyszka-Zawadzka, Anna; Janaszek, Bartosz; Szczepański, Paweł

    2017-04-03

    The tunability of slow light in graphene-based hyperbolic metamaterial waveguide operating in SCLU telecom bands is investigated. For the first time it has been shown that proper design of a GHMM structure forming waveguide layer and the geometry of the waveguide itself allows stopped light to be obtained in an almost freely selected range of wavelengths within SCLU bands. In particular, the possibility of controlling light propagation in GHMM waveguides by external biasing has been presented. The change of external electric field enables the stop light of the selected wavelength as well as the control of a number of modes, which can be stopped, cut off or supported. Proposed GHMM waveguides could offer great opportunities in the field of integrated photonics that are compatible with CMOS technology, especially since such structures can be utilized as photonic memory cells, tunable optical buffers, delays, optical modulators etc.

  16. Polarization modulation based on the hybrid waveguide of graphene sandwiched structure

    NASA Astrophysics Data System (ADS)

    Yang, Junbo; Chen, Dingbo; Zhang, Jingjing; Zhang, Zhaojian; Huang, Jie

    2017-09-01

    Polarization beam splitter (PBS) plays an important role to realize beam control and modulation. A novel hybrid structure of graphene sandwiched waveguide is proposed to fulfill polarization manipulation and selection based on the refractive index engineering techniques. The fundamental mode of TM cannot be supported in this case. However, both TE and TM mode are excited and transmitting in the hybrid waveguide if the design parameters, including the waveguide width and the waveguide height, are changed. The incident wavelength largely affects the effective index, which results in supporting/not supporting the TM mode. The proposed design exhibits high extinction ratio, compact in size, flexible to control, compatible with CMOS process, and easy to be integrated with other optoelectronic devices, allowing it to be used in optical communication and optical information processing.

  17. Optical clock signal distribution and packaging optimization

    NASA Astrophysics Data System (ADS)

    Wu, Linghui

    Polymer-based waveguides for optoelectronic interconnects and packagings were fabricated by a fabrication process that is compatible with the Si CMOS packaging process. An optoelectronic interconnection layer (OIL) for the high-speed massive clock signal distribution for the Cray T-90 supercomputer board employing optical multimode channel waveguides in conjunction with surface-normal waveguide grating couplers and a 1-to-2 3 dB splitter was constructed. Equalized optical paths were realized using an optical H-tree structure having 48 optical fanouts. This device could be increased to 64 without introducing any additional complications. A 1-to-48 fanout H-tree structure using Ultradel 9000D series polyimide was fabricated. The propagation loss and splitting loss have been measured as 0.21 dB/cm and 0.4 dB/splitter at 850 nm. The power budget was discussed, and the H-tree waveguide fully satisfies the power budget requirement. A tapered waveguide coupler was employed to match the mode profile between the single-mode fiber and the multimode channel waveguides of the OIL. A thermo-optical based multimode switch was designed, fabricated, and tested. The finite difference method was used to simulate the thermal distribution in the polymer waveguide. Both stable and transient conditions have been calculated. The thermo-optical switch was fabricated and tested. The switching speed of 1 ms was experimentally confirmed, fitting well with the simulation results. Thermo-optic switching for randomly polarized light at wavelengths of 850 nm was experimental confirmed, as was a stable attenuation of 25 dB. The details of tapered waveguide fabrication were investigated. Compression-molded 3-D tapered waveguides were demonstrated for the first time. Not only the vertical depth variation but also the linear dimensions of the molded waveguides were well beyond the limits of what any other conventional waveguide fabrication method is capable of providing. Molded waveguides with vertical depths of 100 mum at one end and 5 mum at the other end and lengths of 1.0 cm were fabricated using a photolime gel polymer. A propagation loss of 0.5 dB/cm was achieved when light was coupled from the 5 mum x 5 mum end to the 100 mum x 100 mum end and that of 1.1 dB/cm was observed when light was coupled from the 100 mum x 100 mum end to the 5 mum x 5 mum. By confining the energy to the fundamental mode when coupling from the large end to the small end, low-loss packaging can be achieved bi-directionally. 3-D compression-molded polymeric waveguides present a promising solution to bridging the huge dynamic range of different optoelectronic device-depths varying from a few microns to several hundred microns.

  18. Photonic generation of ultra-wide-band doublet pulse through monolithic integration of tapered directional coupler and quantum well waveguide.

    PubMed

    Kuo, Yu-Zheng; Wu, Jui-Pin; Wu, Tsu-Hsiu; Chiu, Yi-Jen

    2012-10-22

    We proposed and demonstrated a novel scheme of photonic ultra-wide-band (UWB) doublet pulse based on monolithic integration of tapered optical-direction coupler (TODC) and multiple-quantum-well (MQW) waveguide. TODC is formed by a top tapered MQW waveguide vertically integrating with an underneath passive waveguide. Through simultaneous field-driven optical index- and absorption- change in MQW, the partial optical coupling in TODC can be used to get a valley-shaped of optical transmission against voltage. Therefore, doublet-enveloped optical pulse can be realized by high-speed and high-efficient conversion of input electrical pulse. By just adjusting bias through MQW, 1530 nm photonic UWB doublet optical pulse with 75-ps pulse width, below -41.3 dBm power, 125% fractional bandwidth, and 7.5 GHz of -10 dB bandwidth has been demonstrated, fitted into FCC requirement (3.1 GHz~10.6 GHz). Doublet-pulse data transmission generated in optical fiber is also performed for further characterization, exhibiting a successful 1.25 Gb/s error-free transmission. It suggests such optoelectronic integration template can be applied for photonic UWB generation in fiber-based communications.

  19. Dielectric waveguide with transverse index variation that support a zero group velocity mode at a non-zero longitudinal wavevector

    DOEpatents

    Ibanescu, Mihai; Joannopoious, John D.; Fink, Yoel; Johnson, Steven G.; Fan, Shanhui

    2005-06-21

    Optical components including a laser based on a dielectric waveguide extending along a waveguide axis and having a refractive index cross-section perpendicular to the waveguide axis, the refractive index cross-section supporting an electromagnetic mode having a zero group velocity for a non-zero wavevector along the waveguide axis.

  20. Porous Silicon-Based Biosensors: Towards Real-Time Optical Detection of Target Bacteria in the Food Industry

    PubMed Central

    Massad-Ivanir, Naama; Shtenberg, Giorgi; Raz, Nitzan; Gazenbeek, Christel; Budding, Dries; Bos, Martine P.; Segal, Ester

    2016-01-01

    Rapid detection of target bacteria is crucial to provide a safe food supply and to prevent foodborne diseases. Herein, we present an optical biosensor for identification and quantification of Escherichia coli (E. coli, used as a model indicator bacteria species) in complex food industry process water. The biosensor is based on a nanostructured, oxidized porous silicon (PSi) thin film which is functionalized with specific antibodies against E. coli. The biosensors were exposed to water samples collected directly from process lines of fresh-cut produce and their reflectivity spectra were collected in real time. Process water were characterized by complex natural micro-flora (microbial load of >107 cell/mL), in addition to soil particles and plant cell debris. We show that process water spiked with culture-grown E. coli, induces robust and predictable changes in the thin-film optical interference spectrum of the biosensor. The latter is ascribed to highly specific capture of the target cells onto the biosensor surface, as confirmed by real-time polymerase chain reaction (PCR). The biosensors were capable of selectively identifying and quantifying the target cells, while the target cell concentration is orders of magnitude lower than that of other bacterial species, without any pre-enrichment or prior processing steps. PMID:27901131

  1. Porous Silicon-Based Biosensors: Towards Real-Time Optical Detection of Target Bacteria in the Food Industry.

    PubMed

    Massad-Ivanir, Naama; Shtenberg, Giorgi; Raz, Nitzan; Gazenbeek, Christel; Budding, Dries; Bos, Martine P; Segal, Ester

    2016-11-30

    Rapid detection of target bacteria is crucial to provide a safe food supply and to prevent foodborne diseases. Herein, we present an optical biosensor for identification and quantification of Escherichia coli (E. coli, used as a model indicator bacteria species) in complex food industry process water. The biosensor is based on a nanostructured, oxidized porous silicon (PSi) thin film which is functionalized with specific antibodies against E. coli. The biosensors were exposed to water samples collected directly from process lines of fresh-cut produce and their reflectivity spectra were collected in real time. Process water were characterized by complex natural micro-flora (microbial load of >10 7  cell/mL), in addition to soil particles and plant cell debris. We show that process water spiked with culture-grown E. coli, induces robust and predictable changes in the thin-film optical interference spectrum of the biosensor. The latter is ascribed to highly specific capture of the target cells onto the biosensor surface, as confirmed by real-time polymerase chain reaction (PCR). The biosensors were capable of selectively identifying and quantifying the target cells, while the target cell concentration is orders of magnitude lower than that of other bacterial species, without any pre-enrichment or prior processing steps.

  2. Porous Silicon-Based Biosensors: Towards Real-Time Optical Detection of Target Bacteria in the Food Industry

    NASA Astrophysics Data System (ADS)

    Massad-Ivanir, Naama; Shtenberg, Giorgi; Raz, Nitzan; Gazenbeek, Christel; Budding, Dries; Bos, Martine P.; Segal, Ester

    2016-11-01

    Rapid detection of target bacteria is crucial to provide a safe food supply and to prevent foodborne diseases. Herein, we present an optical biosensor for identification and quantification of Escherichia coli (E. coli, used as a model indicator bacteria species) in complex food industry process water. The biosensor is based on a nanostructured, oxidized porous silicon (PSi) thin film which is functionalized with specific antibodies against E. coli. The biosensors were exposed to water samples collected directly from process lines of fresh-cut produce and their reflectivity spectra were collected in real time. Process water were characterized by complex natural micro-flora (microbial load of >107 cell/mL), in addition to soil particles and plant cell debris. We show that process water spiked with culture-grown E. coli, induces robust and predictable changes in the thin-film optical interference spectrum of the biosensor. The latter is ascribed to highly specific capture of the target cells onto the biosensor surface, as confirmed by real-time polymerase chain reaction (PCR). The biosensors were capable of selectively identifying and quantifying the target cells, while the target cell concentration is orders of magnitude lower than that of other bacterial species, without any pre-enrichment or prior processing steps.

  3. Coupled resonator optical waveguides based on silicon-on-insulator photonic wires

    NASA Astrophysics Data System (ADS)

    Xia, Fengnian; Sekaric, Lidija; O'Boyle, Martin; Vlasov, Yurii

    2006-07-01

    Coupled resonator optical waveguides (CROWs) comprised of up to 16 racetrack resonators based on silicon-on-insulator (SOI) photonic wires were fabricated and characterized. The optical properties of the CROWs were simulated using measured single resonator parameters based on a matrix approach. The group delay property of CROWs was also analyzed. The SOI based CROWs consisting of multiple resonators have extremely small footprints and can find applications in optical filtering, dispersion compensation, and optical buffering. Moreover, such CROW structure is a promising candidate for exploration of low light level nonlinear optics due to its resonant nature and compact mode size (˜0.1μm2) in photonic wire.

  4. Label-free optical biosensors based on aptamer-functionalized porous silicon scaffolds.

    PubMed

    Urmann, Katharina; Walter, Johanna-Gabriela; Scheper, Thomas; Segal, Ester

    2015-02-03

    A proof-of-concept for a label-free and reagentless optical biosensing platform based on nanostructured porous silicon (PSi) and aptamers is presented in this work. Aptamers are oligonucleotides (single-stranded DNA or RNA) that can bind their targets with high affinity and specificity, making them excellent recognition elements for biosensor design. Here we describe the fabrication and characterization of aptamer-conjugated PSi biosensors, where a previously characterized his-tag binding aptamer (6H7) is used as model system. Exposure of the aptamer-functionalized PSi to the target proteins as well as to complex fluids (i.e., bacteria lysates containing target proteins) results in robust and well-defined changes in the PSi optical interference spectrum, ascribed to specific aptamer-protein binding events occurring within the nanoscale pores, monitored in real time. The biosensors show exceptional stability and can be easily regenerated by a short rinsing step for multiple biosensing analyses. This proof-of-concept study demonstrates the possibility of designing highly stable and specific label-free optical PSi biosensors, employing aptamers as capture probes, holding immense potential for application in detection of a broad range of targets, in a simple yet reliable manner.

  5. Recent advances in electrochemical biosensors based on graphene two-dimensional nanomaterials.

    PubMed

    Song, Yang; Luo, Yanan; Zhu, Chengzhou; Li, He; Du, Dan; Lin, Yuehe

    2016-02-15

    Graphene as a star among two-dimensional nanomaterials has attracted tremendous research interest in the field of electrochemistry due to their intrinsic properties, including the electronic, optical, and mechanical properties associated with their planar structure. The marriage of graphene and electrochemical biosensors has created many ingenious biosensing strategies for applications in the areas of clinical diagnosis and food safety. This review provides a comprehensive overview of the recent advances in the development of graphene based electrochemical biosensors. Special attention is paid to graphene-based enzyme biosensors, immunosensors, and DNA biosensors. Future perspectives on high-performance graphene-based electrochemical biosensors are also discussed. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Plasmonic Biosensors

    PubMed Central

    Hill, Ryan T.

    2015-01-01

    The unique optical properties of plasmon resonant nanostructures enable exploration of nanoscale environments using relatively simple optical characterization techniques. For this reason, the field of plasmonics continues to garner the attention of the biosensing community. Biosensors based on propagating surface plasmon resonances (SPRs) in films are the most well-recognized plasmonic biosensors, but there is great potential for the new, developing technologies to surpass the robustness and popularity of film-based SPR sensing. This review surveys the current plasmonic biosensor landscape with emphasis on the basic operating principles of each plasmonic sensing technique and the practical considerations when developing a sensing platform with the various techniques. The “gold standard” film SPR technique is reviewed briefly, but special emphasis is devoted to the up-and-coming LSPR-based and plasmonically coupled sensor technology. PMID:25377594

  7. Plasmon-assisted optical vias for photonic ASICS

    DOEpatents

    Skogen, Erik J.; Vawter, Gregory A.; Tauke-Pedretti, Anna

    2017-03-21

    The present invention relates to optical vias to optically connect multilevel optical circuits. In one example, the optical via includes a surface plasmon polariton waveguide, and a first optical waveguide formed on a first substrate is coupled to a second optical waveguide formed on a second substrate by the surface plasmon polariton waveguide. In some embodiments, the first optical waveguide includes a transition region configured to convert light from an optical mode to a surface plasmon polariton mode or from a surface plasmon polariton mode to an optical mode.

  8. Design and Fabrication of NxN Optical Couplers Based on Organic Polymer Opti al WaveGuides

    DTIC Science & Technology

    1994-08-01

    lOxlO optical coupler utilizing photopolymerizable organic polymers. Background information on the theory of operation of the coupler culminating in a...Channel Waveguides Based on Photopolymerizable Di/Tri Acrylates," in Optoelecwonic Interconnects Ii, Ray T. Chen, John A. Neff, Editors, Proc. SPIE 2153, pp...demonstrated that acrylic polymers can be used to fabricate single-mode optical wavguides. The resins that we have formulated are photopolymerizable

  9. Laser Development for Gravitational-Wave Interferometry in Space

    NASA Technical Reports Server (NTRS)

    Numata, Kenji; Camp, Jordan

    2012-01-01

    We are reporting on our development work on laser (master oscillator) and optical amplifier systems for gravitational-wave interferometry in space. Our system is based on the mature, wave-guided optics technologies, which have advantages over bulk, crystal-based, free-space optics. We are investing in a new type of compact, low-noise master oscillator, called the planar-waveguide external cavity diode laser. We made measurements, including those of noise, and performed space-qualification tests.

  10. Method for ultrafast optical deflection enabling optical recording via serrated or graded light illumination

    DOEpatents

    Heebner, John E [Livermore, CA

    2009-09-08

    In one general embodiment, a method for deflecting an optical signal input into a waveguide is provided. In operation, an optical input signal is propagated through a waveguide. Additionally, an optical control signal is applied to a mask positioned relative to the waveguide such that the application of the optical control signal to the mask is used to influence the optical input signal propagating in the waveguide. Furthermore, the deflected optical input signal output from the waveguide is detected in parallel on an array of detectors. In another general embodiment, a beam deflecting structure is provided for deflecting an optical signal input into a waveguide, the structure comprising at least one wave guiding layer for guiding an optical input signal and at least one masking layer including a pattern configured to influence characteristics of a material of the guiding layer when an optical control signal is passed through the masking layer in a direction of the guiding layer. In another general embodiment, a system is provided including a waveguide, an attenuating mask positioned on the waveguide, and an optical control source positioned to propagate pulsed laser light towards the attenuating mask and the waveguide such that a pattern of the attenuating mask is applied to the waveguide and material properties of at least a portion of the waveguide are influenced.

  11. On-chip non-reciprocal optical devices based on quantum inspired photonic lattices

    NASA Astrophysics Data System (ADS)

    El-Ganainy, R.; Eisfeld, A.; Levy, Miguel; Christodoulides, D. N.

    2013-10-01

    We propose integrated optical structures that can be used as isolators and polarization splitters based on engineered photonic lattices. Starting from optical waveguide arrays that mimic Fock space (quantum state with a well-defined particle number) representation of a non-interacting two-site Bose Hubbard Hamiltonian, we show that introducing magneto-optic nonreciprocity to these structures leads to a superior optical isolation performance. In the forward propagation direction, an input TM polarized beam experiences a perfect state transfer between the input and output waveguide channels while surface Bloch oscillations block the backward transmission between the same ports. Our analysis indicates a large isolation ratio of 75 dB after a propagation distance of 8 mm inside seven coupled waveguides. Moreover, we demonstrate that, a judicious choice of the nonreciprocity in this same geometry can lead to perfect polarization splitting.

  12. The all-optical modulator in dielectric-loaded waveguide with graphene-silicon heterojunction structure

    NASA Astrophysics Data System (ADS)

    Sun, Feiying; Xia, Liangping; Nie, Changbin; Shen, Jun; Zou, Yixuan; Cheng, Guiyu; Wu, Hao; Zhang, Yong; Wei, Dongshan; Yin, Shaoyun; Du, Chunlei

    2018-04-01

    All-optical modulators based on graphene show great promise for on-chip optical interconnects. However, the modulation performance of all-optical modulators is usually based on the interaction between graphene and the fiber, limiting their potential in high integration. Based on this point, an all-optical modulator in a dielectric-loaded waveguide (DLW) with a graphene-silicon heterojunction structure (GSH) is proposed. The DLW raises the waveguide mode, which provides a strong light-graphene interaction. Sufficient tuning of the graphene Fermi energy beyond the Pauli blocking effect is obtained with the presented GSH structure. Under the modulation light with a wavelength of 532 nm and a power of 60 mW, a modulation efficiency of 0.0275 dB µm-1 is achieved for light with a communication wavelength of 1.55 µm in the experiment. This modulator has the advantage of having a compact footprint, which may make it a candidate for achieving a highly integrated all-optical modulator.

  13. Vertically-tapered optical waveguide and optical spot transformer formed therefrom

    DOEpatents

    Bakke, Thor; Sullivan, Charles T.

    2004-07-27

    An optical waveguide is disclosed in which a section of the waveguide core is vertically tapered during formation by spin coating by controlling the width of an underlying mesa structure. The optical waveguide can be formed from spin-coatable materials such as polymers, sol-gels and spin-on glasses. The vertically-tapered waveguide section can be used to provide a vertical expansion of an optical mode of light within the optical waveguide. A laterally-tapered section can be added adjacent to the vertically-tapered section to provide for a lateral expansion of the optical mode, thereby forming an optical spot-size transformer for efficient coupling of light between the optical waveguide and a single-mode optical fiber. Such a spot-size transformer can also be added to a III-V semiconductor device by post processing.

  14. A 2D Rods-in-Air Square-Lattice Photonic Crystal Optical Switch

    DTIC Science & Technology

    2009-03-01

    4] Tao Chu, Hirohito Yamada, Satomi Ishida, Yasuhiko Arakawa, Thermooptic switch based on photonic-crystal line-defect waveguides, IEEE Photon...Ishida, Yasuhiko Arakawa, Hiroyuki Fujita, Hiroshi Toshiyoshi, Design and fabrication on MEMS optical mod- ulators integrated with Phc waveguide, in

  15. A new method for multi-bit and qudit transfer based on commensurate waveguide arrays

    NASA Astrophysics Data System (ADS)

    Petrovic, J.; Veerman, J. J. P.

    2018-05-01

    The faithful state transfer is an important requirement in the construction of classical and quantum computers. While the high-speed transfer is realized by optical-fibre interconnects, its implementation in integrated optical circuits is affected by cross-talk. The cross-talk between densely packed optical waveguides limits the transfer fidelity and distorts the signal in each channel, thus severely impeding the parallel transfer of states such as classical registers, multiple qubits and qudits. Here, we leverage on the suitably engineered cross-talk between waveguides to achieve the parallel transfer on optical chip. Waveguide coupling coefficients are designed to yield commensurate eigenvalues of the array and hence, periodic revivals of the input state. While, in general, polynomially complex, the inverse eigenvalue problem permits analytic solutions for small number of waveguides. We present exact solutions for arrays of up to nine waveguides and use them to design realistic buses for multi-(qu)bit and qudit transfer. Advantages and limitations of the proposed solution are discussed in the context of available fabrication techniques.

  16. CMOS-compatible 2-bit optical spectral quantization scheme using a silicon-nanocrystal-based horizontal slot waveguide

    PubMed Central

    Kang, Zhe; Yuan, Jinhui; Zhang, Xianting; Wu, Qiang; Sang, Xinzhu; Farrell, Gerald; Yu, Chongxiu; Li, Feng; Tam, Hwa Yaw; Wai, P. K. A.

    2014-01-01

    All-optical analog-to-digital converters based on the third-order nonlinear effects in silicon waveguide are a promising candidate to overcome the limitation of electronic devices and are suitable for photonic integration. In this paper, a 2-bit optical spectral quantization scheme for on-chip all-optical analog-to-digital conversion is proposed. The proposed scheme is realized by filtering the broadened and split spectrum induced by the self-phase modulation effect in a silicon horizontal slot waveguide filled with silicon-nanocrystal. Nonlinear coefficient as high as 8708 W−1/m is obtained because of the tight mode confinement of the horizontal slot waveguide and the high nonlinear refractive index of the silicon-nanocrystal, which provides the enhanced nonlinear interaction and accordingly low power threshold. The results show that a required input peak power level less than 0.4 W can be achieved, along with the 1.98-bit effective-number-of-bit and Gray code output. The proposed scheme can find important applications in on-chip all-optical digital signal processing systems. PMID:25417847

  17. Ink-jet printed fluorescent materials as light sources for planar optical waveguides on polymer foils

    NASA Astrophysics Data System (ADS)

    Bollgruen, Patrick; Gleissner, Uwe; Wolfer, Tim; Megnin, Christof; Mager, Dario; Overmeyer, Ludger; Korvink, Jan G.; Hanemann, Thomas

    2016-10-01

    Polymer-based optical sensor networks on foils (planar optronic systems) are a promising research field, but it can be challenging to supply them with light. We present a solvent-free, ink-jet printable material system with optically active substances to create planar light sources for these networks. The ink is based on a UV-curable monomer, the fluorescent agents are EuDBMPhen or 9,10-diphenylantracene, which fluoresce at 612 or 430 nm, respectively. We demonstrate the application as light source by printing a small area of fluorescent material on an optical waveguide fabricated by flexographic printing on PMMA foil, resulting in a simple polymer-optical device fabricated entirely by additive deposition techniques. When excited by a 405-nm laser of 10 mW, the emitted light couples into the waveguide and appears at the end of the waveguide. In comparison to conventional light sources, the intensity is weak but could be detected with a photodiode power sensor. In return, the concept has the advantage of being completely independent of any electrical elements or external cable connections.

  18. CMOS-compatible 2-bit optical spectral quantization scheme using a silicon-nanocrystal-based horizontal slot waveguide.

    PubMed

    Kang, Zhe; Yuan, Jinhui; Zhang, Xianting; Wu, Qiang; Sang, Xinzhu; Farrell, Gerald; Yu, Chongxiu; Li, Feng; Tam, Hwa Yaw; Wai, P K A

    2014-11-24

    All-optical analog-to-digital converters based on the third-order nonlinear effects in silicon waveguide are a promising candidate to overcome the limitation of electronic devices and are suitable for photonic integration. In this paper, a 2-bit optical spectral quantization scheme for on-chip all-optical analog-to-digital conversion is proposed. The proposed scheme is realized by filtering the broadened and split spectrum induced by the self-phase modulation effect in a silicon horizontal slot waveguide filled with silicon-nanocrystal. Nonlinear coefficient as high as 8708 W(-1)/m is obtained because of the tight mode confinement of the horizontal slot waveguide and the high nonlinear refractive index of the silicon-nanocrystal, which provides the enhanced nonlinear interaction and accordingly low power threshold. The results show that a required input peak power level less than 0.4 W can be achieved, along with the 1.98-bit effective-number-of-bit and Gray code output. The proposed scheme can find important applications in on-chip all-optical digital signal processing systems.

  19. Detection of bioagents using a shear horizontal surface acoustic wave biosensor

    DOEpatents

    Larson, Richard S; Hjelle, Brian; Hall, Pam R; Brown, David C; Bisoffi, Marco; Brozik, Susan M; Branch, Darren W; Edwards, Thayne L; Wheeler, David

    2014-04-29

    A biosensor combining the sensitivity of surface acoustic waves (SAW) generated at a frequency of 325 MHz with the specificity provided by antibodies and other ligands for the detection of viral agents. In a preferred embodiment, a lithium tantalate based SAW transducer with silicon dioxide waveguide sensor platform featuring three test and one reference delay lines was used to adsorb antibodies directed against Coxsackie virus B4 or the negative-stranded category A bioagent Sin Nombre virus (SNV). Rapid detection of increasing concentrations of viral particles was linear over a range of order of magnitude for both viruses, and the sensor's selectivity for its target was not compromised by the presence of confounding Herpes Simplex virus type 1 The biosensor was able to delect SNV at doses lower than the load of virus typically found in a human patient suffering from hantavirus cardiopulmonary syndrome (HCPS).

  20. Ridge Waveguide Structures in Magnesium-Doped Lithium Niobate

    NASA Technical Reports Server (NTRS)

    Himmer, Phillip; Battle, Philip; Suckow, William; Switzer, Greg

    2011-01-01

    This work proposes to establish the feasibility of fabricating isolated ridge waveguides in 5% MgO:LN. Ridge waveguides in MgO:LN will significantly improve power handling and conversion efficiency, increase photonic component integration, and be well suited to spacebased applications. The key innovation in this effort is to combine recently available large, high-photorefractive-damage-threshold, z-cut 5% MgO:LN with novel ridge fabrication techniques to achieve high-optical power, low-cost, high-volume manufacturing of frequency conversion structures. The proposed ridge waveguide structure should maintain the characteristics of the periodically poled bulk substrate, allowing for the efficient frequency conversion typical of waveguides and the high optical damage threshold and long lifetimes typical of the 5% doped bulk substrate. The low cost and large area of 5% MgO:LN wafers, and the improved performance of the proposed ridge waveguide structure, will enhance existing measurement capabilities as well as reduce the resources required to achieve high-performance specifications. The purpose of the ridge waveguides in MgO:LN is to provide platform technology that will improve optical power handling and conversion efficiency compared to existing waveguide technology. The proposed ridge waveguide is produced using standard microfabrication techniques. The approach is enabled by recent advances in inductively coupled plasma etchers and chemical mechanical planarization techniques. In conjunction with wafer bonding, this fabrication methodology can be used to create arbitrarily shaped waveguides allowing complex optical circuits to be engineered in nonlinear optical materials such as magnesium doped lithium niobate. Researchers here have identified NLO (nonlinear optical) ridge waveguide structures as having suitable value to be the leading frequency conversion structures. Its value is based on having the low-cost fabrication necessary to satisfy the challenging pricing requirements as well as achieve the power handling and other specifications in a suitably compact package.

  1. Controlling propagation and coupling of waveguide modes using phase-gradient metasurfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Zhaoyi; Kim, Myoung -Hwan; Wang, Cheng

    Here, research on two-dimensional designer optical structures, or metasurfaces, has mainly focused on controlling the wavefronts of light propagating in free space. Here, we show that gradient metasurface structures consisting of phased arrays of plasmonic or dielectric nanoantennas can be used to control guided waves via strong optical scattering at subwavelength intervals. Based on this design principle, we experimentally demonstrate waveguide mode converters, polarization rotators and waveguide devices supporting asymmetric optical power transmission. We also demonstrate all-dielectric on-chip polarization rotators based on phased arrays of Mie resonators with negligible insertion losses. Our gradient metasurfaces can enable small-footprint, broadband and low-lossmore » photonic integrated devices.« less

  2. Controlling propagation and coupling of waveguide modes using phase-gradient metasurfaces

    DOE PAGES

    Li, Zhaoyi; Kim, Myoung -Hwan; Wang, Cheng; ...

    2017-04-17

    Here, research on two-dimensional designer optical structures, or metasurfaces, has mainly focused on controlling the wavefronts of light propagating in free space. Here, we show that gradient metasurface structures consisting of phased arrays of plasmonic or dielectric nanoantennas can be used to control guided waves via strong optical scattering at subwavelength intervals. Based on this design principle, we experimentally demonstrate waveguide mode converters, polarization rotators and waveguide devices supporting asymmetric optical power transmission. We also demonstrate all-dielectric on-chip polarization rotators based on phased arrays of Mie resonators with negligible insertion losses. Our gradient metasurfaces can enable small-footprint, broadband and low-lossmore » photonic integrated devices.« less

  3. Polymer microfiber bridging Bi-tapered refractive index sensor based on evanescent field

    NASA Astrophysics Data System (ADS)

    Lv, Ri-Qing; Wang, Qi; Wang, Bo-Tao; Liu, Yu; Kong, Lingxin

    2018-05-01

    A PDMS/graphene enhanced PMMA micro optical waveguide sensor is reported in terms of fabrication method and optical characteristics. The micro optical waveguide with a diameter of 6 μm and a length of 800 μm is used as the sensing probe to realize refractive index (RI) measurement suspended in NaCl solutions with different concentrations. Experimental results show that the refractive index sensing sensitivity can reach 2027.97 nm/RIU within the refractive index ranging from 1.3333-1.3426. Research results show that PMMA/graphene micro optical waveguide doped with PDMS is an excellent high sensitive sensing technology in refractive index detection field.

  4. A tunable optofluidic circular liquid fiber

    NASA Astrophysics Data System (ADS)

    Li, Lei; Wu, Wei; Shi, Yang; Gong, Enze; Yang, Yi

    2016-01-01

    This paper presents a tunable optofluidic circular liquid fiber through the numerical simulation. Fiber is a significant optical device and has been widely applied on optical fiber communication. But the fiber based solid has limited tunability. Compared to solid fiber, the fiber based liquid material is relatively infrequent. Cause for the liquid optical device has more freedom tunable properties than solid counterpart, it has attracted more interest. The traditional optofluidic waveguide is designed like a sandwich in planar channel. This two-dimensional (2D) structure liquid waveguide will face huge transmission loss in the perpendicular direction of the flow streams. In this paper, a curving microchannel is designed inside the microchip to produce centrifugal effect. Two different liquids are injected into the chip by external pumps. In a particular situation, the core flow will be totally surrounded by the cladding flow. So the liquid can form an optical waveguide. Its structure is similar to an optical fiber which high refractive index (RI) liquid is core of the waveguide and the low RI liquid is cladding of the waveguide. Profit from the reconfigurability of liquid material, this liquid fiber has excellent tunability. The diameter of the core flow can be tuned in a wider range by changing the volume ratio of the flows through the finite element analysis. It is predictable that such a tunable liquid fiber may find wider applications in lab-on-a-chip systems and integrated optical devices.

  5. Towards a manufacturing ecosystem for integrated photonic sensors (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Miller, Benjamin L.

    2017-03-01

    Laboratory-scale demonstrations of optical biosensing employing structures compatible with CMOS fabrication, including waveguides, Mach-Zehnder interferometers, ring resonators, and photonic crystals, have provided ample validation of the promise of these technologies. However, to date there are relatively few examples of integrated photonic biosensors in the commercial sphere. The lack of successful translation from the laboratory to the marketplace is due in part to a lack of robust manufacturing processes for integrated photonics overall. This talk will describe efforts within the American Institute for Manufacturing Photonics (AIM Photonics), a public-private consortium funded by the Department of Defense, State governments, Universities, and Corporate partners to accelerate manufacturing of integrated photonic sensors.

  6. Highly sensitive nano-porous lattice biosensor based on localized surface plasmon resonance and interference.

    PubMed

    Yeom, Se-Hyuk; Kim, Ok-Geun; Kang, Byoung-Ho; Kim, Kyu-Jin; Yuan, Heng; Kwon, Dae-Hyuk; Kim, Hak-Rin; Kang, Shin-Won

    2011-11-07

    We propose a design for a highly sensitive biosensor based on nanostructured anodized aluminum oxide (AAO) substrates. A gold-deposited AAO substrate exhibits both optical interference and localized surface plasmon resonance (LSPR). In our sensor, application of these disparate optical properties overcomes problems of limited sensitivity, selectivity, and dynamic range seen in similar biosensors. We fabricated uniform periodic nanopore lattice AAO templates by two-step anodizing and assessed their suitability for application in biosensors by characterizing the change in optical response on addition of biomolecules to the AAO template. To determine the suitability of such structures for biosensing applications, we immobilized a layer of C-reactive protein (CRP) antibody on a gold coating atop an AAO template. We then applied a CRP antigen (Ag) atop the immobilized antibody (Ab) layer. The shift in reflectance is interpreted as being caused by the change in refractive index with membrane thickness. Our results confirm that our proposed AAO-based biosensor is highly selective toward detection of CRP antigen, and can measure a change in CRP antigen concentration of 1 fg/ml. This method can provide a simple, fast, and sensitive analysis for protein detection in real-time.

  7. Laser-assisted patterning of double-sided adhesive tapes for optofluidic chip integration

    NASA Astrophysics Data System (ADS)

    Zamora, Vanessa; Janeczka, Christian; Arndt-Staufenbiel, Norbert; Havlik, George; Queisser, Marco; Schröder, Henning

    2018-02-01

    Portable high-sensitivity biosensors exhibit a growing demand in healthcare, food industry and environmental monitoring sectors. Optical biosensors based on photonic integration platforms are attractive candidates due to their high sensitivity, compactness and multiplexing capabilities. However, they need a low-cost and reliable integration with the microfluidic system. Laser-micropatterned double-sided biocompatible adhesive tapes are promising bonding layers for hybrid integration of an optofluidic biochip. As a part of the EU-PHOCNOSIS project, double-sided adhesive tapes have been proposed to integrate the polymer microfluidic system with the optical integrated waveguide sensor chip. Here the adhesive tape should be patterned in a micrometer scale in order to create an interaction between the sample that flows through the polymer microchannel and the photonic sensing microstructure. Three laser-assisted structuring methods are investigated to transfer microchannel patterns to the adhesive tape. The test structure design consists of a single channel with 400 μm wide, 30 mm length and two circular receivers with 3 mm radius. The best structuring results are found by using the picosecond UV laser where smooth and straight channel cross-sections are obtained. Such patterned tapes are used to bond blank polymer substrates to blank silicon substrates. As a proof of concept, the hybrid integration is tested using colored DI-water. Structuring tests related to the reduction of channel widths are also considered in this work. The use of this technique enables a simple and rapid manufacturing of narrow channels (50-60 μm in width) in adhesive tapes, achieving a cheap and stable integration of the optofluidic biochip.

  8. Manufacturing of embedded multimode waveguides by reactive lamination of cyclic olefin polymer and polymethylmethacrylate

    NASA Astrophysics Data System (ADS)

    Kelb, Christian; Rother, Raimund; Schuler, Anne-Katrin; Hinkelmann, Moritz; Rahlves, Maik; Prucker, Oswald; Müller, Claas; Rühe, Jürgen; Reithmeier, Eduard; Roth, Bernhard

    2016-03-01

    We demonstrate the manufacturing of embedded multimode optical waveguides through linking of polymethylmethacrylate (PMMA) foils and cyclic olefin polymer (COP) filaments based on a lamination process. Since the two polymeric materials cannot be fused together through interdiffusion of polymer chains, we utilize a reactive lamination agent based on PMMA copolymers containing photoreactive 2-acryloyloxyanthraquinone units, which allows the creation of monolithic PMMA-COP substrates through C-H insertion reactions across the interface between the two materials. We elucidate the lamination process and evaluate the chemical link between filament and foils by carrying out extraction tests with a custom-built tensile testing machine. We also show attenuation measurements of the manufactured waveguides for different manufacturing parameters. The lamination process is in particular suited for large-scale and low-cost fabrication of board-level devices with optical waveguides or other micro-optical structures, e.g., optofluidic devices.

  9. A unique all-optic switch based on an innovatively designed liquid crystal waveguide

    NASA Astrophysics Data System (ADS)

    Nam, Sung-Hyun; Su, Wei-Hung; Chavez, Jesus; Yin, Shizhuo

    2003-10-01

    A unique, all-optic switch based on an innovatively designed planar lightwave circuit (PLC) is presented in this paper. The switching function is achieved by using ultra large birefringence of nematic liquid crystals (NLC) filled at the trench of waveguides. The trench at the crossing forms a waveguide mirror or a matching medium when extraordinary and ordinary refractive indices of NLC are employed, respectively. The major advantages of our unique design are: (1) the limitation that refractive index of liquid crystal must be less than that of waveguide material itself is eliminated so that conventional NCL material such as E7 can be used; (2) it is a self aligned fabrication process that alleviates the tight tolerance of later tilt error; (3) the design is thermally stable. The successful fabrication of this unqiue switch could result in an enabling element for the next generation all-optic networks.

  10. Realization of 10 GHz minus 30dB on-chip micro-optical links with Si-Ge RF bi-polar technology

    NASA Astrophysics Data System (ADS)

    Ogudo, Kingsley A.; Snyman, Lukas W.; Polleux, Jean-Luc; Viana, Carlos; Tegegne, Zerihun

    2014-06-01

    Si Avalanche based LEDs technology has been developed in the 650 -850nm wavelength regime [1, 2]. Correspondingly, small micro-dimensioned detectors with pW/μm2 sensitivity have been developed for the same wavelength range utilizing Si-Ge detector technology with detection efficiencies of up to 0.85, and with a transition frequencies of up to 80 GHz [3] A series of on-chip optical links of 50 micron length, utilizing 650 - 850 nm propagation wavelength have been designed and realized, utilizing a Si Ge radio frequency bipolar process. Micron dimensioned optical sources, waveguides and detectors were all integrated on the same chip to form a complete optical link on-chip. Avalanche based Si LEDs (Si Av LEDs), Schottky contacting, TEOS densification strategies, silicon nitride based waveguides, and state of the art Si-Ge bipolar detector technologies were used as key design strategies. Best performances show optical coupling from source to detector of up to 10GHz and - 40dBm total optical link budget loss with a potential transition frequency coupling of up to 40GHz utilizing Si Ge based LEDs. The technology is particularly suitable for application as on-chip optical links, optical MEMS and MOEMS, as well as for optical interconnects utilizing low loss, side surface, waveguide- to-optical fiber coupling. Most particularly is one of our designed waveguide which have a good core axis alignment with the optical source and yield 10GHz -30dB on-chip micro-optical links as shown in Fig 9 (c). The technology as developed has been appropriately IP protected.

  11. Direct Wafer Bonding and Its Application to Waveguide Optical Isolators

    PubMed Central

    Mizumoto, Tetsuya; Shoji, Yuya; Takei, Ryohei

    2012-01-01

    This paper reviews the direct bonding technique focusing on the waveguide optical isolator application. A surface activated direct bonding technique is a powerful tool to realize a tight contact between dissimilar materials. This technique has the potential advantage that dissimilar materials are bonded at low temperature, which enables one to avoid the issue associated with the difference in thermal expansion. Using this technique, a magneto-optic garnet is successfully bonded on silicon, III-V compound semiconductors and LiNbO3. As an application of this technique, waveguide optical isolators are investigated including an interferometric waveguide optical isolator and a semileaky waveguide optical isolator. The interferometric waveguide optical isolator that uses nonreciprocal phase shift is applicable to a variety of waveguide platforms. The low refractive index of buried oxide layer in a silicon-on-insulator (SOI) waveguide enhances the magneto-optic phase shift, which contributes to the size reduction of the isolator. A semileaky waveguide optical isolator has the advantage of large fabrication-tolerance as well as a wide operation wavelength range. PMID:28817020

  12. Design of highly sensitive multichannel bimetallic photonic crystal fiber biosensor

    NASA Astrophysics Data System (ADS)

    Hameed, Mohamed Farhat O.; Alrayk, Yassmin K. A.; Shaalan, Abdelhamid A.; El Deeb, Walid S.; Obayya, Salah S. A.

    2016-10-01

    A design of a highly sensitive multichannel biosensor based on photonic crystal fiber is proposed and analyzed. The suggested design has a silver layer as a plasmonic material coated by a gold layer to protect silver oxidation. The reported sensor is based on detection using the quasi transverse electric (TE) and quasi transverse magnetic (TM) modes, which offers the possibility of multichannel/multianalyte sensing. The numerical results are obtained using a finite element method with perfect matched layer boundary conditions. The sensor geometrical parameters are optimized to achieve high sensitivity for the two polarized modes. High-refractive index sensitivity of about 4750 nm/RIU (refractive index unit) and 4300 nm/RIU with corresponding resolutions of 2.1×10-5 RIU, and 2.33×10-5 RIU can be obtained according to the quasi TM and quasi TE modes of the proposed sensor, respectively. Further, the reported design can be used as a self-calibration biosensor within an unknown analyte refractive index ranging from 1.33 to 1.35 with high linearity and high accuracy. Moreover, the suggested biosensor has advantages in terms of compactness and better integration of microfluidics setup, waveguide, and metallic layers into a single structure.

  13. Measurement of ultrafast optical Kerr effect of Ge-Sb-Se chalcogenide slab waveguides by the beam self-trapping technique

    NASA Astrophysics Data System (ADS)

    Kuriakose, Tintu; Baudet, Emeline; Halenkovič, Tomáš; Elsawy, Mahmoud M. R.; Němec, Petr; Nazabal, Virginie; Renversez, Gilles; Chauvet, Mathieu

    2017-11-01

    We present a reliable and original experimental technique based on the analysis of beam self-trapping to measure ultrafast optical nonlinearities in planar waveguides. The technique is applied to the characterization of Ge-Sb-Se chalcogenide films that allow Kerr induced self-focusing and soliton formation. Linear and nonlinear optical constants of three different chalcogenide waveguides are studied at 1200 and 1550 nm in femtosecond regime. Waveguide propagation loss and two photon absorption coefficients are determined by transmission analysis. Beam broadening and narrowing results are compared with simulations of the nonlinear Schrödinger equation solved by BPM method to deduce the Kerr n2 coefficients. Kerr optical nonlinearities obtained by our original technique compare favorably with the values obtained by Z-scan technique. Nonlinear refractive index as high as (69 ± 11) × 10-18m2 / W is measured in Ge12.5Sb25Se62.5 at 1200 nm with low nonlinear absorption and low propagation losses which reveals the great characteristics of our waveguides for ultrafast all optical switching and integrated photonic devices.

  14. Light coupling for on-chip optical interconnects

    NASA Astrophysics Data System (ADS)

    Gao, Xumin; Yuan, Jialei; Yang, Yongchao; Li, Yuanhang; Cai, Wei; Li, Xin; Wang, Yongjin

    2017-12-01

    An on-chip optical interconnect of a light emitter, waveguide and photodetector based on p-n junction InGaN/GaN multiple quantum wells (MQWs) is fabricated to investigate the light coupling efficiency of suspended waveguides connecting the light emitter and photodetector. Optical characterizations indicate that the photocurrent of the photodetector is mainly induced by the emitted light that is transmitted through the waveguides. Suspended waveguides with and without air gaps are reported in this paper. A 1 mA current injection into the light emitter induces a photocurrent of 17.3 nA and 205.5 nA for the photodetector connected to the waveguides that with 10 μm air gaps and without air gaps, respectively. Finite-difference time-domain simulations are performed to analyze the gap effect on the coupling efficiency of the light transmission. Both the gap distance and the index variation of the gap materials are analyzed to verify the potential optical sensing functions of the on-chip optical interconnect. A possible strategy for increasing the light coupling efficiency is proven by simulations.

  15. Process development for waveguide chemical sensors with integrated polymeric sensitive layers

    NASA Astrophysics Data System (ADS)

    Amberkar, Raghu; Gao, Zhan; Park, Jongwon; Henthorn, David B.; Kim, Chang-Soo

    2008-02-01

    Due to the proper optical property and flexibility in the process development, an epoxy-based, high-aspect ratio photoresist SU-8 is now attracting attention in optical sensing applications. Manipulation of the surface properties of SU-8 waveguides is critical to attach functional films such as chemically-sensitive layers. We describe a new integration process to immobilize fluorescence molecules on SU-8 waveguide surface for application to intensity-based optical chemical sensors. We use two polymers for this application. Spin-on, hydrophobic, photopatternable silicone is a convenient material to contain fluorophore molecules and to pattern a photolithographically defined thin layer on the surface of SU-8. We use fumed silica powders as an additive to uniformly disperse the fluorophores in the silicone precursor. In general, additional processes are not critically required to promote the adhesion between the SU-8 and silicone. The other material is polyethylene glycol diacrylate (PEGDA). Recently we demonstrated a novel photografting method to modify the surface of SU-8 using a surface bound initiator to control its wettability. The activated surface is then coated with a monomer precursor solution. Polymerization follows when the sample is exposed to UV irradiation, resulting in a grafted PEGDA layer incorporating fluorophores within the hydrogel matrix. Since this method is based the UV-based photografting reaction, it is possible to grow off photolithographically defined hydrogel patterns on the waveguide structures. The resulting films will be viable integrated components in optical bioanalytical sensors. This is a promising technique for integrated chemical sensors both for planar type waveguide and vertical type waveguide chemical sensors.

  16. Compact and low power operation optical switch using silicon-germanium/silicon hetero-structure waveguide.

    PubMed

    Sekiguchi, Shigeaki; Kurahashi, Teruo; Zhu, Lei; Kawaguchi, Kenichi; Morito, Ken

    2012-04-09

    We proposed a silicon-based optical switch with a carrier-plasma-induced phase shifter which employs a silicon-germanium (SiGe) / silicon (Si) hetero-structure in the waveguide core. A type-I hetero-interface formed by SiGe and Si is expected to confine carriers effectively in the SiGe waveguide core. The fabricated Mach-Zehnder optical switch shows a low switching power of only 1.53 mW with a compact phase shifter length of 250 μm. The switching time of the optical switch is less than 4.6 ns for the case of a square waveform driving condition, and 1 ns for the case of a pre-emphasis electric driving condition. These results show that our proposed SiGe/Si waveguide structure holds promise for active devices with compact size and low operation power.

  17. Electrically Tunable Nd:YAG waveguide laser based on Graphene

    PubMed Central

    Ma, Linan; Tan, Yang; Akhmadaliev, Shavkat; Zhou, Shengqiang; Chen, Feng

    2016-01-01

    We demonstrate a tunable hybrid Graphene-Nd:YAG cladding waveguide laser exploiting the electro-optic and the Joule heating effects of Graphene. A cladding Nd:YAG waveguide was fabricated by the ion irradiation. The multi-layer graphene were transferred onto the waveguide surface as the saturable absorber to get the Q-switched pulsed laser oscillation in the waveguide. Composing with appropriate electrodes, graphene based capacitance and heater were formed on the surface of the Nd:YAG waveguide. Through electrical control of graphene, the state of the hybrid waveguide laser was turned on or off. And the laser operation of the hybrid waveguide was electrically tuned between the continuous wave laser and the nanosecond pulsed laser. PMID:27833114

  18. Waveguide metatronics: Lumped circuitry based on structural dispersion

    PubMed Central

    Li, Yue; Liberal, Iñigo; Della Giovampaola, Cristian; Engheta, Nader

    2016-01-01

    Engineering optical nanocircuits by exploiting modularization concepts and methods inherited from electronics may lead to multiple innovations in optical information processing at the nanoscale. We introduce the concept of “waveguide metatronics,” an advanced form of optical metatronics that uses structural dispersion in waveguides to obtain the materials and structures required to construct this class of circuitry. Using numerical simulations, we demonstrate that the design of a metatronic circuit can be carried out by using a waveguide filled with materials with positive permittivity. This includes the implementation of all “lumped” circuit elements and their assembly in a single circuit board. In doing so, we extend the concepts of optical metatronics to frequency ranges where there are no natural plasmonic materials available. The proposed methodology could be exploited as a platform to experimentally validate optical metatronic circuits in other frequency regimes, such as microwave frequency setups, and/or to provide a new route to design optical nanocircuitry. PMID:27386566

  19. Polarization-dependent plasmonic splitter based on low-loss polymer optical materials

    NASA Astrophysics Data System (ADS)

    Qian, Guang; Fu, Xing-Chang; Zhang, Li-Jiang; Liu, Yi-Ran; Zhao, Ning; Zhang, Tong

    2018-01-01

    A polarization-dependent optical beam splitter consisting of a straight long-range surface plasmon polariton (LRSPP) waveguide and an S-bend polymer waveguide was designed, fabricated and measured in this paper. At the splitting section, the two different waveguides are vertically coupled. The measurenment results show that the splitter operated in dual-channel mode at TM polarization, and single-channel mode at TE polarization. In addition, the polymer waveguide and LRSPP waveguide in the splitter exhibit low propagation loss of 0.51 dB/cm and 1.7 dB/cm, respectively. The hybrid beam splitter has wide potential applications in three dimensional (3D) multilayer photonic integrated circuits (PICs).

  20. Microfiber Optical Sensors: A Review

    PubMed Central

    Lou, Jingyi; Wang, Yipei; Tong, Limin

    2014-01-01

    With diameter close to or below the wavelength of guided light and high index contrast between the fiber core and the surrounding, an optical microfiber shows a variety of interesting waveguiding properties, including widely tailorable optical confinement, evanescent fields and waveguide dispersion. Among various microfiber applications, optical sensing has been attracting increasing research interest due to its possibilities of realizing miniaturized fiber optic sensors with small footprint, high sensitivity, fast response, high flexibility and low optical power consumption. Here we review recent progress in microfiber optical sensors regarding their fabrication, waveguide properties and sensing applications. Typical microfiber-based sensing structures, including biconical tapers, optical gratings, circular cavities, Mach-Zehnder interferometers and functionally coated/doped microfibers, are summarized. Categorized by sensing structures, microfiber optical sensors for refractive index, concentration, temperature, humidity, strain and current measurement in gas or liquid environments are reviewed. Finally, we conclude with an outlook for challenges and opportunities of microfiber optical sensors. PMID:24670720

  1. Polymeric variable optical attenuators based on magnetic sensitive stimuli materials

    NASA Astrophysics Data System (ADS)

    de Pedro, S.; Cadarso, V. J.; Ackermann, T. N.; Muñoz-Berbel, X.; Plaza, J. A.; Brugger, J.; Büttgenbach, S.; Llobera, A.

    2014-12-01

    Magnetically-actuable, polymer-based variable optical attenuators (VOA) are presented in this paper. The design comprises a cantilever which also plays the role of a waveguide and the input/output alignment elements for simple alignment, yet still rendering an efficient coupling. Magnetic properties have been conferred to these micro-opto-electromechanical systems (MOEMS) by implementing two different strategies: in the first case, a magnetic sensitive stimuli material (M-SSM) is obtained by a combination of polydimethylsiloxane (PDMS) and ferrofluid (FF) in ratios between 14.9 wt % and 29.9 wt %. An M-SSM strip under the waveguide-cantilever, defined with soft lithography (SLT), provides the required actuation capability. In the second case, specific volumes of FF are dispensed at the end of the cantilever tip (outside the waveguide) by means of inkjet printing (IJP), obtaining the required magnetic response while holding the optical transparency of the waveguide-cantilever. In the absence of a magnetic field, the waveguide-cantilever is aligned with the output fiber optics and thus the intrinsic optical losses can be obtained. Numerical simulations, validated experimentally, have shown that, for any cantilever length, the VOAs defined by IJP present lower intrinsic optical losses than their SLT counterparts. Under an applied magnetic field (Bapp), both VOA configurations experience a misalignment between the waveguide-cantilever and the output fiber optics. Thus, the proposed VOAs modulate the output power as a function of the cantilever displacement, which is proportional to Bapp. The experimental results for the three different waveguide-cantilever lengths and six different FF concentrations (three per technology) show maximum deflections of 220 µm at 29.9 wt % of FF for VOASLT and 250 µm at 22.3 wt % FF for VOAIJP, at 0.57 kG for both. These deflections provide maximum actuation losses of 16.1 dB and 18.9 dB for the VOASLT and VOAIJP, respectively.

  2. Evaluation of hybrid polymers for high-precision manufacturing of 3D optical interconnects by two-photon absorption lithography

    NASA Astrophysics Data System (ADS)

    Schleunitz, A.; Klein, J. J.; Krupp, A.; Stender, B.; Houbertz, R.; Gruetzner, G.

    2017-02-01

    The fabrication of optical interconnects has been widely investigated for the generation of optical circuit boards. Twophoton absorption (TPA) lithography (or high-precision 3D printing) as an innovative production method for direct manufacture of individual 3D photonic structures gains more and more attention when optical polymers are employed. In this regard, we have evaluated novel ORMOCER-based hybrid polymers tailored for the manufacture of optical waveguides by means of high-precision 3D printing. In order to facilitate future industrial implementation, the processability was evaluated and the optical performance of embedded waveguides was assessed. The results illustrate that hybrid polymers are not only viable consumables for industrial manufacture of polymeric micro-optics using generic processes such as UV molding. They also are potential candidates to fabricate optical waveguide systems down to the chip level where TPA-based emerging manufacturing techniques are engaged. Hence, it is shown that hybrid polymers continue to meet the increasing expectations of dynamically growing markets of micro-optics and optical interconnects due to the flexibility of the employed polymer material concept.

  3. Low loss hollow-core waveguide on a silicon substrate

    NASA Astrophysics Data System (ADS)

    Yang, Weijian; Ferrara, James; Grutter, Karen; Yeh, Anthony; Chase, Chris; Yue, Yang; Willner, Alan E.; Wu, Ming C.; Chang-Hasnain, Connie J.

    2012-07-01

    Optical-fiber-based, hollow-core waveguides (HCWs) have opened up many new applications in laser surgery, gas sensors, and non-linear optics. Chip-scale HCWs are desirable because they are compact, light-weight and can be integrated with other devices into systems-on-a-chip. However, their progress has been hindered by the lack of a low loss waveguide architecture. Here, a completely new waveguiding concept is demonstrated using two planar, parallel, silicon-on-insulator wafers with high-contrast subwavelength gratings to reflect light in-between. We report a record low optical loss of 0.37 dB/cm for a 9-μm waveguide, mode-matched to a single mode fiber. Two-dimensional light confinement is experimentally realized without sidewalls in the HCWs, which is promising for ultrafast sensing response with nearly instantaneous flow of gases or fluids. This unique waveguide geometry establishes an entirely new scheme for low-cost chip-scale sensor arrays and lab-on-a-chip applications.

  4. Three-dimensional negative index of refraction at optical frequencies by coupling plasmonic waveguides.

    PubMed

    Verhagen, Ewold; de Waele, René; Kuipers, L; Polman, Albert

    2010-11-26

    We identify a route towards achieving a negative index of refraction at optical frequencies based on coupling between plasmonic waveguides that support backwards waves. We show how modal symmetry can be exploited in metal-dielectric waveguide pairs to achieve negative refraction of both phase and energy. Control of waveguide coupling yields a metamaterial consisting of a one-dimensional multilayer stack that exhibits an isotropic index of -1 at a free-space wavelength of 400 nm. The concepts developed here may inspire new low-loss metamaterial designs operating close to the metal plasma frequency.

  5. A multifunctional material based on co-electrospinning for developing biosensors with optical oxygen transduction.

    PubMed

    Ramon-Marquez, Teresa; Medina-Castillo, Antonio L; Nagiah, Naveen; Fernandez-Gutierrez, Alberto; Fernandez-Sanchez, Jorge F

    2018-07-26

    A multifunctional material based on co-electrospinning has been developed as a basic material for the development of biosensors with optical oxygen transduction. It is based on coaxial nanofibres: inner fibres containing an oxygen sensitive dye and outer fibres containing aldehyde groups to allow the formation of Schiff bases with the amino groups of the enzyme. The resulting material preserves the oxygen sensing properties of the inner optical transducer as well as exhibits a high capacity for immobilizing molecules on its surface. Uricase has been selected as model enzyme and several parameters (temperature, pH, reaction time, buffer, and enzyme concentration) have been optimised to demonstrate the versatility of this novel multifunctional material in the development of biosensors with optical oxygen transduction for determining uric acid in serum samples. It suggests that the proposed multifunctional material can provide a promising multifunctional platform for biosensing applications. Copyright © 2018 Elsevier B.V. All rights reserved.

  6. Ultra-fast all-optical plasmon induced transparency in a metal–insulator–metal waveguide containing two Kerr nonlinear ring resonators

    NASA Astrophysics Data System (ADS)

    Nurmohammadi, Tofiq; Abbasian, Karim; Yadipour, Reza

    2018-05-01

    In this work, an ultra-fast all-optical plasmon induced transparency based on a metal–insulator–metal nanoplasmonic waveguide with two Kerr nonlinear ring resonators is studied. Two-dimensional simulations utilizing the finite-difference time-domain method are used to show an obvious optical bistability and significant switching mechanisms of the signal light by varying the pump-light intensity. The proposed all-optical switching based on plasmon induced transparency demonstrates femtosecond-scale feedback time (90 fs), meaning ultra-fast switching can be achieved. The presented all-optical switch may have potential significant applications in integrated optical circuits.

  7. Frequency-degenerate phase-sensitive optical parametric amplification based on four-wave mixing in graphene–silicon slot waveguide

    NASA Astrophysics Data System (ADS)

    Li, Zhen; Liu, Hongjun; Huang, Nan; Wang, Zhaolu; Han, Jing

    2018-06-01

    The phase-sensitive amplification process of a hybrid graphene–silicon (HyGS) slot waveguide with trilayers of graphene is investigated in this paper. Numerical simulation shows that a relatively high extinction ratio (42 dB) is achieved, because of the ultrahigh nonlinear coefficients, with a waveguide length of only 680 µm. In addition, the graphene layer provides the possibility of modulating the phase status and gain of the output signal. This study is expected to be highly beneficial to applications such as integrated optics and graphene-related active optical devices.

  8. Slow light enhanced optical nonlinearity in a silicon photonic crystal coupled-resonator optical waveguide.

    PubMed

    Matsuda, Nobuyuki; Kato, Takumi; Harada, Ken-Ichi; Takesue, Hiroki; Kuramochi, Eiichi; Taniyama, Hideaki; Notomi, Masaya

    2011-10-10

    We demonstrate highly enhanced optical nonlinearity in a coupled-resonator optical waveguide (CROW) in a four-wave mixing experiment. Using a CROW consisting of 200 coupled resonators based on width-modulated photonic crystal nanocavities in a line defect, we obtained an effective nonlinear constant exceeding 10,000 /W/m, thanks to slow light propagation combined with a strong spatial confinement of light achieved by the wavelength-sized cavities.

  9. Silicon photonics thermal phase shifter with reduced temperature range

    DOEpatents

    Lentine, Anthony L; Kekatpure, Rohan D; DeRose, Christopher; Davids, Paul; Watts, Michael R

    2013-12-17

    Optical devices, phased array systems and methods of phase-shifting an input signal are provided. An optical device includes a microresonator and a waveguide for receiving an input optical signal. The waveguide includes a segment coupled to the microresonator with a coupling coefficient such that the waveguide is overcoupled to the microresonator. The microresonator received the input optical signal via the waveguide and phase-shifts the input optical signal to form an output optical signal. The output optical signal is coupled into the waveguide via the microresonator and transmitted by the waveguide. At an operating point of the optical device, the coupling coefficient is selected to reduce a change in an amplitude of the output optical signal and to increase a change in a phase of the output optical signal, relative to the input optical signal.

  10. Design and application of fiber optic evanescent wave biosensor

    NASA Astrophysics Data System (ADS)

    Huang, Huijie; Zhai, Junhui; Zhao, Yongkai; Yang, Ruifu; Ren, Bingqiang; Cheng, Zhaogu; Du, Longlong; Lu, Dunwu

    2003-12-01

    A fiber-optic biosensor is developed based on the principle of evanescent wave while light propagates in optical fiber. The biosensor uses a red laser diode at 636.85 nm for exciting Cy5 fluorescent dye. Sensitivity limit of 0.01 nnmol/l is obtained from the detection of serial Cy5 solutions with various concentrations. In log-to-log plot, excellent linear response characteristic is seen in the Cy5 concentrations ranging from 0.01 nmlo/l to 100 nmol/l. And a good result of signal-to-noise ratio of 4.61 is obtained when the biosensor is used to measure Legionella pneumophila solution of 0.01 μmol/l. All the results are comparable with those that are obtained by a commercial biochip scanner GeneTAC 1000.

  11. On-chip integratable all-optical quantizer using strong cross-phase modulation in a silicon-organic hybrid slot waveguide

    PubMed Central

    Kang, Zhe; Yuan, Jinhui; Zhang, Xianting; Sang, Xinzhu; Wang, Kuiru; Wu, Qiang; Yan, Binbin; Li, Feng; Zhou, Xian; Zhong, Kangping; Zhou, Guiyao; Yu, Chongxiu; Farrell, Gerald; Lu, Chao; Yaw Tam, Hwa; Wai, P. K. A.

    2016-01-01

    High performance all-optical quantizer based on silicon waveguide is believed to have significant applications in photonic integratable optical communication links, optical interconnection networks, and real-time signal processing systems. In this paper, we propose an integratable all-optical quantizer for on-chip and low power consumption all-optical analog-to-digital converters. The quantization is realized by the strong cross-phase modulation and interference in a silicon-organic hybrid (SOH) slot waveguide based Mach-Zehnder interferometer. By carefully designing the dimension of the SOH waveguide, large nonlinear coefficients up to 16,000 and 18,069 W−1/m for the pump and probe signals can be obtained respectively, along with a low pulse walk-off parameter of 66.7 fs/mm, and all-normal dispersion in the wavelength regime considered. Simulation results show that the phase shift of the probe signal can reach 8π at a low pump pulse peak power of 206 mW and propagation length of 5 mm such that a 4-bit all-optical quantizer can be realized. The corresponding signal-to-noise ratio is 23.42 dB and effective number of bit is 3.89-bit. PMID:26777054

  12. Analytical study of optical bistability in silicon-waveguide resonators.

    PubMed

    Rukhlenko, Ivan D; Premaratne, Malin; Agrawal, Govind P

    2009-11-23

    We present a theoretical model that describes accurately the nonlinear phenomenon of optical bistability in silicon-waveguide resonators but remains amenable to analytical results. Using this model, we derive a transcendental equation governing the intensity of a continuous wave transmitted through a Fabry-Perot resonator formed using a silicon-on-insulator waveguide. This equation reveals a dual role of free carriers in the formation of optical bistability in silicon. First, it shows that free-carrier absorption results in a saturation of the transmitted intensity. Second, the free-carrier dispersion and the thermo-optic effect may introduce phase shifts far exceeding those resulting from the Kerr effect alone, thus enabling one to achieve optical bistability in ultrashort resonators that are only a few micrometers long. Bistability can occur even when waveguide facets are not coated because natural reflectivity of the silicon- r interface can provide sufficient feedback. We find that it is possible to control the input-output characteristics of silicon-based resonators by changing the free-carrier lifetime using a reverse-biased p-n junction. We show theoretically that such a technique is suitable for realization of electronically assisted optical switching at a fixed input power and it may lead to silicon-based, nanometer-size, optical memories.

  13. Theoretical description and design of nanomaterial slab waveguides: application to compensation of optical diffraction.

    PubMed

    Kivijärvi, Ville; Nyman, Markus; Shevchenko, Andriy; Kaivola, Matti

    2018-04-02

    Planar optical waveguides made of designable spatially dispersive nanomaterials can offer new capabilities for nanophotonic components. As an example, a thin slab waveguide can be designed to compensate for optical diffraction and provide divergence-free propagation for strongly focused optical beams. Optical signals in such waveguides can be transferred in narrow channels formed by the light itself. We introduce here a theoretical method for characterization and design of nanostructured waveguides taking into account their inherent spatial dispersion and anisotropy. Using the method, we design a diffraction-compensating slab waveguide that contains only a single layer of silver nanorods. The waveguide shows low propagation loss and broadband diffraction compensation, potentially allowing transfer of optical information at a THz rate.

  14. Integrated optical components in thin films of polymers

    NASA Technical Reports Server (NTRS)

    Sarkisov, Sergey; Abdeldayem, Hossin; Venkateswarlu, Putcha; Teague, Zedric

    1995-01-01

    The results will be reported on the study of integrated optical components based on nonlinear optical polymeric films. Polymers poly(methyl methacrylate) (PMMA) and polyimide (PI) doped with organic laser dyes 4-dicyanomethylene-2-methyl-6-p dimethylaminostyryl-4H pyran (DCM) and 1, 3, 5, 7, 8 - pentamethyl-2,6 -diethyl-pyrromethene -BF2-complex (Pyrommethene 567, PM-567) were selected as materials for light guiding films. Additionally, UV polymerized polydiacetylene (PDA) on glass substrate was used as a waveguide material. Optical waveguides were fabricated using spin coating of preoxidized silicon wafers (1.5 micrometer silicon oxide layer) with organic dye/polymer solution followed by soft baking. the modes in slab waveguides were studied using prism coupling techniques. Measured values of mode coupling angles in multimode waveguides were used to calculate film thickness and refractive index for different polarizations. Refractive index anisotropy was found in PDA waveguide. The optimal conditions of spin coating for single mode waveguide fabrication were estimated. Propagation losses were measured by collecting the light scattered from the trace of a propagating mode either by scanning photo detector or by CCD camera. Different types of light coupling techniques were used including end-dire coupling, prism and grating coupling. Mechanical printing technique was developed for coupling grating fabrication resulting in gratings with 4% diffraction efficiency. The gratings demonstrated good stability with diffraction efficiency relaxation rate 2.4 dB/hour at a temperature approximately 15-20 C below glass transition point. Dye doped waveguides were transversally pumped with frequency doubled Nd:YAG Q-switched laser producing intensive light emission with apparent 6 kW/sq cm pump threshold and spectrum narrowing near 617 nm peak in the case of DCM doped waveguide. PM-567 doped waveguide pumped with CW Ar(+) laser (514 nm wavelength) far below threshold (0.1 W/sq.cm pump power) demonstrated emission spectrum narrowing near 616 nm peak with 18% power conversion slope efficiency. In this case emission spectrum modification was caused by the enhanced light absorption along the direction of propagating waveguide modes. Changing length, thickness, and other morphlogical waveguide parameters one can modify emission spectrum in predictable direction. The results show that polymeric waveguides, especially based on high temperature polymers such as Pl, can be used to produce a varietiy of active and passive silicon compatible integrated optical components for aerospace applications.

  15. Extraordinary optical transmission inside a waveguide: spatial mode dependence.

    PubMed

    Reichel, Kimberly S; Lu, Peter Y; Backus, Sterling; Mendis, Rajind; Mittleman, Daniel M

    2016-12-12

    We study the influence of the input spatial mode on the extraordinary optical transmission (EOT) effect. By placing a metal screen with a 1D array of subwavelength holes inside a terahertz (THz) parallel-plate waveguide (PPWG), we can directly compare the transmission spectra with different input waveguide modes. We observe that the transmitted spectrum depends strongly on the input mode. A conventional description of EOT based on the excitation of surface plasmons is not predictive in all cases. Instead, we utilize a formalism based on impedance matching, which accurately predicts the spectral resonances for both TEM and non-TEM input modes.

  16. Propagation and switching of light in rectangular waveguiding structures

    NASA Astrophysics Data System (ADS)

    Sala, Anca L.

    1998-10-01

    In this dissertation, we investigate the conditions for the propagation and processing of temporal optical solitons in the rectangular geometry waveguides which are expected to play an important role as processing elements in optical communication systems. It is anticipated that the optical signals carrying information through optical fibers will be in the form of temporal soliton pulses, which can propagate undistorted for long distances under the condition that the dispersion is balanced by a nonlinearity in the optical fiber. An important parameter in the equation that governs temporal soliton propagation in a waveguide is the second derivative of the propagation vector with respect to the angular frequency, /omega, denoted by β/prime'. We evaluate β/prime' for rectangular waveguides using a channel model of the waveguide, which takes into account the two transverse dimensions of the rectangular channel. Significant differences are found in the values of β/prime' obtained from our model and those obtained from the more traditional, one dimensional slab model. A major additional effort in the present thesis relates to the development of a theory of temporal soliton switching in a planar geometry nonlinear directional coupler. The theory is formulated in terms of the supermodes of the total structure, and again accounts for the two transverse dimensions of the channels. To accurately determine the coupling length and switching power of the nonlinear coupler, we apply corrections to the propagation constants of the supermodes that account for the non-zero electromagnetic fields in the outer corner regions of the waveguide channels. It is shown for the case of a SiO2 based nonlinear directional coupler operating at the central wavelength of 1.55 μm, that these corrections have a significant effect on both the coupling length and the switching power. Finally, we develop the conditions under which single mode rectangular waveguides can have zero dispersion at the optical communications wavelengths 1.31 μm or 1.55 μm, and discuss the end-to-end coupling of rectangular waveguides to the standard optical fibers used in optical communications. Our results are expected to serve as a guide for the design of planar geometry based processing elements in a variety of optical communications devices.

  17. All-optical Integrated Switches Based on Azo-benzene Liquid Crystals on Silicon

    DTIC Science & Technology

    2011-11-01

    Glass D263 SU8 Polymer Polymer NLC n̂ n̂ Refractive index @1.55 µm Materials n// = 1.689 n⊥= 1.502 n = 1.575 n = 1.516 E7 Glass D263 SU8 ...In the other case we have a nonlinear LCW based on glass substrates. It consists in a rectangular hollow realized in SU8 photoresist two glass...and discussion 5. All optical polymeric waveguide: methods, assumptions and procedure 6. All optical polymeric waveguide: results and discussion 7

  18. Spatial mode discriminator based on leaky waveguides

    NASA Astrophysics Data System (ADS)

    Xu, Jing; Liu, Jialing; Shi, Hongkang; Chen, Yuntian

    2018-06-01

    We propose a conceptually simple and experimentally compatible configuration to discriminate the spatial mode based on leaky waveguides, which are inserted in-between the transmission link. The essence of such a spatial mode discriminator is to introduce the leakage of the power flux on purpose for detection. Importantly, the leaky angle of each individual spatial mode with respect to the propagation direction are different for non-degenerated modes, while the radiation patterns of the degenerated spatial modes in the plane perpendicular to the propagation direction are also distinguishable. Based on these two facts, we illustrate the operation principle of the spatial mode discriminators via two concrete examples; a w-type slab leaky waveguide without degeneracy, and a cylindrical leaky waveguide with degeneracy. The correlation between the leakage angle and the spatial mode distribution for a slab leaky waveguide, as well as differences between the in-plane radiation patterns of degenerated modes in a cylindrical leaky waveguide, are verified numerically and analytically. Such findings can be readily useful in discriminating the spatial modes for optical communication or optical sensing.

  19. Optofluidic devices for biomolecule sensing and multiplexing

    NASA Astrophysics Data System (ADS)

    Ozcelik, Damla

    Optofluidics which integrates photonics and microfluidics, has led to highly compact, sensitive and adaptable biomedical sensors. Optofluidic biosensors based on liquid-core anti-resonant reflecting optical waveguides (LC-ARROWs), have proven to be a highly sensitive, portable, and reconfigurable platform for fluorescence spectroscopy and detection of single biomolecules such as proteins, nucleic acids, and virus particles. However, continued improvements in sensitivity remain a major goal as we approach the ultimate limit of detecting individual bio-particles labeled by single or few fluorophores. Additionally, the ability to simultaneously detect and identify multiple biological particles or biomarkers is one of the key requirements for molecular diagnostic tests. The compactness and adaptability of these platforms can further be advanced by introducing tunability, integrating off-chip components, designing reconfigurable and customizable devices, which makes these platforms very good candidates for many different applications. The goal of this thesis was to introduce new elements in these LC-ARROW optofluidics platforms that provide major enhancements in their functionality, making them more sensitive, compact, customizable and multiplexed. First, a novel integrated tunable spectral filter that achieves effective elimination of background noise on the ARROW platform was demonstrated. A unique dual liquid-core design enabled the independent multi-wavelength tuning of the spectral filter by adjusting the refractive index and chemical properties of the liquid. In order to enhance the detection sensitivity of the platform, Y-splitter waveguides were integrated to create multiple excitation spots for each target molecule. A powerful signal processing algorithm was used to analyze the data to improve the signal-to-noise ratio (SNR) of the collected data. Next, the design, optimization and characterization of the Y-splitter waveguides are presented; and single influenza virus detection with an improved SNR was demonstrated using this platform. Finally, multiplexing capacity is introduced to the ARROW detection platform by integrating multi-mode interference (MMI) waveguides. MMI waveguides create wavelength dependent multiple excitation spots at the excitation region, allowing the spectral multiplexed detection of multiple different target molecules based on the excitation pattern, without the need for additional spectral filters. Successful spectral multiplexed detection of three different types of influenza viruses is achieved by using separate wavelengths and combination of wavelengths. This multiplexing capacity is further enhanced by taking advantage of the spatial properties of the MMI pattern, designing triple liquid-core waveguides that intersect the MMI waveguide in different locations. Furthermore, the spectral and spatial multiplexing capacities are combined in these triple liquid-core MMI platforms, allowing these devices to distinguish multiple different targets and samples simultaneously.

  20. Low- and high-index sol-gel films for planar and channel-doped waveguides

    NASA Astrophysics Data System (ADS)

    Canva, Michael; Chaput, Frederic; Lahlil, Khalid; Rachet, Vincent; Goudket, Helene; Boilot, Jean-Pierre; Levy, Yves

    2001-11-01

    In view of realizing integrated optic components based on effects such as electro-optic, chi(2):chi(2) cascading, stimulated emission,... one has to first synthesize materials with the proper functionality; this may be achieved by doping solid state matrices by the appropriate organic chromophores. Second, and as important, these materials have to be properly structured into the final optical guiding structures. We shall report on issues related to the realization of chromophore-doped planar waveguides as well as channel waveguides. These structures were realized by either photo-transformation such as photo- chromism and photo-bleaching or reactive ion etching technique, starting with chromophore doped sol-gel materials at high loading contents for which optical index may be controlled via the local dopant concentration. With these materials and techniques, waveguides and components characterized by propagation losses of the order of a cm-1, measured off the edge of the absorption band of the doping species, were fabricated. In order to be also able to study and use waveguide functionalized with low concentration of chromophore species, we developed new sol-gel materials of high optical index, yet low temperature processed. These new films are under study to evaluate their potential as host for organic doped waveguides devices.

  1. Dielectric waveguide gas-filled stark shift modulator

    DOEpatents

    Hutchinson, Donald P.; Richards, Roger K.

    2003-07-22

    An optical modulator includes a dielectric waveguide for receiving an optical beam and coupling energy of the optical beam into the waveguide. At least one Stark material is provided in the waveguide. A bias circuit generates a bias signal to produce an electrical field across the Stark material to shift at least one of the Stark absorption frequencies towards the frequency of the optical beam. A circuit for producing a time varying electric field across the Stark material modulates the optical beam. At least a portion of the bias field can be generated by an alternating bias signal, such as a square wave. A method of modulating optical signals includes the steps of providing a dielectric waveguide for receiving an optical beam and coupling energy of the optical beam into the waveguide, the waveguide having at least one Stark material disposed therein, and varying an electric field imposed across the Stark material.

  2. High Performance Hermetic Package For LiNbO3 Electro-Optic Waveguide Devices

    NASA Astrophysics Data System (ADS)

    Preston, K. R.; Macdonald, B. M.; Harmon, R. A.; Ford, C. W.; Shaw, R. N.; Reid, I.; Davidson, J. H.; Beaumont, A. R.; Booth, R. C.

    1989-02-01

    A high performance fibre-tailed package for LiNbO3 electro-optic waveguide devices is described. The package is based around a hermetic metal submodule which contains no epoxy or other organic materials. The LiNbO3 chip is mounted using a soldering technique, and laser welding is used for fibre fixing to give stable, low loss optical coupling to single mode fibres. Optical reflections are minimised by the use of antireflective coatings on the fibre ends and waveguide facets. High speed electrical connections are made via coplanar glass-sealed leadthroughs to LiNb03 travelling wave devices, and packaged device operation to frequencies in excess of 4GHz is demonstrated.

  3. Serum protein measurement using a tapered fluorescent fibre-optic evanescent wave-based biosensor

    NASA Astrophysics Data System (ADS)

    Preejith, P. V.; Lim, C. S.; Chia, T. F.

    2006-12-01

    A novel method to measure the total serum protein concentration is described in this paper. The method is based on the principles of fibre-optic evanescent wave spectroscopy. The biosensor applies a fluorescent dye-immobilized porous glass coating on a multi-mode optical fibre. The evanescent wave's intensity at the fibre-optic core-cladding interface is used to monitor the protein-induced changes in the sensor element. The sensor offers a rapid, single-step method for quantifying protein concentrations without destroying the sample. This unique sensing method presents a sensitive and accurate platform for the quantification of protein.

  4. Fabrication of 8×8 MMI optical coupler in BK7 by ion-exchange

    NASA Astrophysics Data System (ADS)

    Li, Xia; Li, Xi-Hua; Zhou, Qiang; Jiang, Xiao-Qing; Yang, Jian-Yi; Wang, Ming-Hua

    2005-01-01

    The planar waveguide optical couplers are of prime importance in optical communication and optical signal processing system. Comparing with the optical fiber coupler (OFC) which fabricated by fused biconical taper technology, the planar waveguide couplers are more compact size, lower loss, better uniformity, easier manufacture and integration. Multimode interference (MMI) couplers have many advantages, such as compact size, wavelength and polarization insensitivity, fabrication tolerances and low loss, etc., which concentrate more and more attention. Conventional MMI devices are based on the uniform index waveguides. When the number of input/output waveguides becomes larger, the intrinsic propagation constant error, which will cause bad uniformity of output power, can"t be neglected. In fact, most waveguide devices are graded-index. With the enhanced compatibility of MMI coupler, the performance can be improved at the same time. Prior study shows that graded-index MMI couplers reach the best performance under certain index contrast. Among many available materials, glass is chosen to be the substrate of the coupler, because of its good features, such as low loss, ease fabrication, cheap cost, and so on. In this paper, an 8×8 MMI optical coupler is designed based on the principle of graded-index MMI. The coupler is composed of a waveguide, which is designed to support a large number of modes, and several access (usually single-mode) waveguides, which are used to launch light into and recover light from that multimode waveguide. The total length of the device is less than 3.5 centimeter, including S-bends which lead the multiple images to the output of the device with the spacing D=250μm to make the device fiber compatible. In this paper, we describe an experimental realization of the 8×8 graded-index MMI optical coupler and the measurement of its performance with the testing laser of the wavelength of 1.55μm. The device is fabricated by ion-exchange on BK7 glass substrate. During the ion-exchange process, a melting mixture of AgNO3 : (KNO3 : NaNO3) (molar ratio, 0.001:1) is used at 350~380°C for different times (range from 8 to 18 hours) to fabricate the coupler. The experimental results show that the performance of the optical coupler is quite promising. For instance, while launching light from No.5 waveguide, the uniformity of the device is approximately 0.72dB. Optimization of design and fabrication is going on to improve the total performance of the optical coupler.

  5. Plasmonic biosensors.

    PubMed

    Hill, Ryan T

    2015-01-01

    The unique optical properties of plasmon resonant nanostructures enable exploration of nanoscale environments using relatively simple optical characterization techniques. For this reason, the field of plasmonics continues to garner the attention of the biosensing community. Biosensors based on propagating surface plasmon resonances (SPRs) in films are the most well-recognized plasmonic biosensors, but there is great potential for the new, developing technologies to surpass the robustness and popularity of film-based SPR sensing. This review surveys the current plasmonic biosensor landscape with emphasis on the basic operating principles of each plasmonic sensing technique and the practical considerations when developing a sensing platform with the various techniques. The 'gold standard' film SPR technique is reviewed briefly, but special emphasis is devoted to the up-and-coming localized surface plasmon resonance and plasmonically coupled sensor technology. © 2014 Wiley Periodicals, Inc.

  6. Simultaneous quasi-one-dimensional propagation and tuning of upconversion luminescence through waveguide effect

    PubMed Central

    Gao, Dangli; Tian, Dongping; Zhang, Xiangyu; Gao, Wei

    2016-01-01

    Luminescence-based waveguide is widely investigated as a promising alternative to conquer the difficulties of efficiently coupling light into a waveguide. But applications have been still limited due to employing blue or ultraviolet light as excitation source with the lower penetration depth leading to a weak guided light. Here, we show a quasi-one-dimensional propagation of luminescence and then resulting in a strong luminescence output from the top end of a single NaYF4:Yb3+/Er3+ microtube under near infrared light excitation. The mechanism of upconversion propagation, based on the optical waveguide effect accompanied with energy migration, is proposed. The efficiency of luminescence output is highly dependent on the concentration of dopant ions, excitation power, morphology, and crystallinity of tube as an indirect evidence of the existence of the optical actived waveguide effect. These findings provide the possibility for the construction of upconversion fiber laser. PMID:26926491

  7. Nonlinear optical coupler using a doped optical waveguide

    DOEpatents

    Pantell, Richard H.; Sadowski, Robert W.; Digonnet, Michel J. F.; Shaw, Herbert J.

    1994-01-01

    An optical mode coupling apparatus includes an Erbium-doped optical waveguide in which an optical signal at a signal wavelength propagates in a first spatial propagation mode and a second spatial propagation mode of the waveguide. The optical signal propagating in the waveguide has a beat length. The coupling apparatus includes a pump source of perturbational light signal at a perturbational wavelength that propagates in the waveguide in the first spatial propagation mode. The perturbational signal has a sufficient intensity distribution in the waveguide that it causes a perturbation of the effective refractive index of the first spatial propagation mode of the waveguide in accordance with the optical Kerr effect. The perturbation of the effective refractive index of the first spatial propagation mode of the optical waveguide causes a change in the differential phase delay in the optical signal propagating in the first and second spatial propagation modes. The change in the differential phase delay is detected as a change in the intensity distribution between two lobes of the optical intensity distribution pattern of an output signal. The perturbational light signal can be selectively enabled and disabled to selectively change the intensity distribution in the two lobes of the optical intensity distribution pattern.

  8. Optical coupling of bare optoelectronic components and flexographically printed polymer waveguides in planar optronic systems

    NASA Astrophysics Data System (ADS)

    Wang, Yixiao; Wolfer, Tim; Lange, Alex; Overmeyer, Ludger

    2016-05-01

    Large scale, planar optronic systems allowing spatially distributed functionalities can be well used in diverse sensor networks, such as for monitoring the environment by measuring various physical quantities in medicine or aeronautics. In these systems, mechanically flexible and optically transparent polymeric foils, e.g. polymethyl methacrylate (PMMA) and polyethylene terephthalate (PET), are employed as carrier materials. A benefit of using these materials is their low cost. The optical interconnections from light sources to light transmission structures in planar optronic systems occupy a pivotal position for the sensing functions. As light sources, we employ the optoelectronic components, such as edgeemitting laser diodes, in form of bare chips, since their extremely small structures facilitate a high integration compactness and ensure sufficient system flexibility. Flexographically printed polymer optical waveguides are deployed as light guiding structures for short-distance communication in planar optronic systems. Printing processes are utilized for this generation of waveguides to achieve a cost-efficient large scale and high-throughput production. In order to attain a high-functional optronic system for sensing applications, one of the most essential prerequisites is the high coupling efficiency between the light sources and the waveguides. Therefore, in this work, we focus on the multimode polymer waveguide with a parabolic cross-section and investigate its optical coupling with the bare laser diode. We establish the geometrical model of the alignment based on the previous works on the optodic bonding of bare laser diodes and the fabrication process of polymer waveguides with consideration of various parameters, such as the beam profile of the laser diode, the employed polymer properties of the waveguides as well as the carrier substrates etc. Accordingly, the optical coupling of the bare laser diodes and the polymer waveguides was simulated. Additionally, we demonstrate optical links by adopting the aforementioned processes used for defining the simulation. We verify the feasibility of the developed processes for planar optronic systems by using an active alignment and conduct discussions for further improvements of optical alignment.

  9. Mid-infrared materials and devices on a Si platform for optical sensing

    PubMed Central

    Singh, Vivek; Lin, Pao Tai; Patel, Neil; Lin, Hongtao; Li, Lan; Zou, Yi; Deng, Fei; Ni, Chaoying; Hu, Juejun; Giammarco, James; Soliani, Anna Paola; Zdyrko, Bogdan; Luzinov, Igor; Novak, Spencer; Novak, Jackie; Wachtel, Peter; Danto, Sylvain; Musgraves, J David; Richardson, Kathleen; Kimerling, Lionel C; Agarwal, Anuradha M

    2014-01-01

    In this article, we review our recent work on mid-infrared (mid-IR) photonic materials and devices fabricated on silicon for on-chip sensing applications. Pedestal waveguides based on silicon are demonstrated as broadband mid-IR sensors. Our low-loss mid-IR directional couplers demonstrated in SiNx waveguides are useful in differential sensing applications. Photonic crystal cavities and microdisk resonators based on chalcogenide glasses for high sensitivity are also demonstrated as effective mid-IR sensors. Polymer-based functionalization layers, to enhance the sensitivity and selectivity of our sensor devices, are also presented. We discuss the design of mid-IR chalcogenide waveguides integrated with polycrystalline PbTe detectors on a monolithic silicon platform for optical sensing, wherein the use of a low-index spacer layer enables the evanescent coupling of mid-IR light from the waveguides to the detector. Finally, we show the successful fabrication processing of our first prototype mid-IR waveguide-integrated detectors. PMID:27877641

  10. Theory of absorption integrated optical sensor of gaseous materials

    NASA Astrophysics Data System (ADS)

    Egorov, A. A.

    2010-10-01

    The eigen and noneigen (leaky) modes of a three-layer planar integrated optical waveguide are described. The dispersion relation of a three-layer planar waveguide and other dependences are derived, and the cutoff conditions are analyzed. The diagram of propagation constants of the guided and radiation modes of an irregular asymmetric three-layer waveguide and the dependence of the electric field amplitudes of radiation modes of substrate on vertical coordinate in a tantalum integrated optical waveguide are presented. The operating principles of an absorption integrated optical waveguide sensor are investigated. The dependences of sensitivity of an integrated optical waveguide sensor on the sensory cell length, the coupling efficiency of the laser radiation into the waveguide, the absorption cross-section of the studied material, and the level of additive statistical noise are investigated. Some of the prospective areas of application of integrated-optical waveguide sensors are outlined.

  11. Silica waveguide devices and their applications

    NASA Astrophysics Data System (ADS)

    Sun, C. J.; Schmidt, Kevin M.; Lin, Wenhua

    2005-03-01

    Silica waveguide technology transitioned from laboratories to commercial use in early 1990. Since then, various applications have been exploited based on this technology. Tens of thousands of array waveguide grating (AWG) devices have been installed worldwide for DWDM Mux and Demux. The recent FTTH push in Japan has renewed the significance of this technology for passive optical network (PON) application. This paper reviews the past development of this technology, compare it with competing technologies, and outline the future role of this technology in the evolving optical communications.

  12. Application de la technologie des materiaux sol-gel et polymere a l'optique integree

    NASA Astrophysics Data System (ADS)

    Saddiki, Zakaria

    2002-01-01

    With the advancement of optical telecommunication systems, "integrated optics" and "optical interconnect" technology are becoming more and more important. The major components of these two technologies are photonic integrated circuits (PICs), optoelectronic integrated circuits (OEICs), and optoelectronic multichip modules ( OE-MCMs). Optical signals are transmitted through optical waveguides that interconnect such components. The principle of optical transmission in waveguides is the same as that in optical fibres. To implement these technologies, both passive and active optical devices are needed. A wide variety of optical materials has been studied, e.g., glasses, lithium niobate, III-V semiconductors, sol-gel and polymers. In particular, passive optical components have been fabricated using glass optical waveguides by ion-exchange, or by flame hydrolysis deposition and reactive ion etching (FHD and RIE ). When using FHD and RIE, a very high temperatures (up to 1300°C) are needed to consolidate silica. This work reports on the fabrication and characterization of a new photo-patternable hybrid organic-inorganic glass sol-gel and polymer materials for the realisation of integrated optic and opto-electronic devices. They exhibit low losses in the NIR range, especially at the most important wavelengths windows for optical communications (1320 nm and 1550 nm). The sol-gel and polymer process is based on photo polymerization and thermo polymerization effects to create the wave-guide. The single-layer film is at low temperature and deep UV-light is employed to make the wave-guide by means of the well-known photolithography process. Like any photo-imaging process, the UV energy should exceed the threshold energy of chemical bonds in the photoactive component of hybrid glass material to form the expected integrated optic pattern with excellent line width control and vertical sidewalls. To achieve optical wave-guide, a refractive index difference Delta n occurred between the isolated (guiding layer) and the surrounding region (buffer and cladding). Accordingly, the refractive index emerges as a fundamental device performance material parameter and it is investigated using slab wave-guide. (Abstract shortened by UMI.)

  13. Broadband athermal waveguides and devices for datacom and telecom applications

    NASA Astrophysics Data System (ADS)

    He, Liuqing; Guo, Yuhao; Han, Zhaohong; Wada, Kazumi; Kimerling, Lionel C.; Michel, Jurgen; Agarwal, Anuradha M.; Li, Guifang; Zhang, Lin

    2018-02-01

    The high temperature sensitivity of silicon material limits the applications of silicon-based micro-ring resonators in integrated photonics. To realize a low but broadband temperature-dependence-wavelength-shift (TDWS) micro-ring resonator, designing a broadband athermal waveguide becomes a significant task. In this work, we propose a broadband athermal waveguide which shows a low effective thermos-optical coefficient (TOC) of +/-1×10-6/K at 1400 nm to 1700 nm. The proposed waveguide shows low-loss performance of 0.01 dB/cm and stable broadband-athermal ability when it's applied in micro-ring resonators, and the optical loss of micro-ring resonator with a radius of 100 μm using this waveguide is 0.02 dB/cm.

  14. Scalable electro-photonic integration concept based on polymer waveguides

    NASA Astrophysics Data System (ADS)

    Bosman, E.; Van Steenberge, G.; Boersma, A.; Wiegersma, S.; Harmsma, P.; Karppinen, M.; Korhonen, T.; Offrein, B. J.; Dangel, R.; Daly, A.; Ortsiefer, M.; Justice, J.; Corbett, B.; Dorrestein, S.; Duis, J.

    2016-03-01

    A novel method for fabricating a single mode optical interconnection platform is presented. The method comprises the miniaturized assembly of optoelectronic single dies, the scalable fabrication of polymer single mode waveguides and the coupling to glass fiber arrays providing the I/O's. The low cost approach for the polymer waveguide fabrication is based on the nano-imprinting of a spin-coated waveguide core layer. The assembly of VCSELs and photodiodes is performed before waveguide layers are applied. By embedding these components in deep reactive ion etched pockets in the silicon substrate, the planarity of the substrate for subsequent layer processing is guaranteed and the thermal path of chip-to-substrate is minimized. Optical coupling of the embedded devices to the nano-imprinted waveguides is performed by laser ablating 45 degree trenches which act as optical mirror for 90 degree deviation of the light from VCSEL to waveguide. Laser ablation is also implemented for removing parts of the polymer stack in order to mount a custom fabricated connector containing glass fiber arrays. A demonstration device was built to show the proof of principle of the novel fabrication, packaging and optical coupling principles as described above, combined with a set of sub-demonstrators showing the functionality of the different techniques separately. The paper represents a significant part of the electro-photonic integration accomplishments in the European 7th Framework project "Firefly" and not only discusses the development of the different assembly processes described above, but the efforts on the complete integration of all process approaches into the single device demonstrator.

  15. Waveguide bends from nanometric silica wires

    NASA Astrophysics Data System (ADS)

    Tong, Limin; Lou, Jingyi; Mazur, Eric

    2005-02-01

    We propose to use bent silica wires with nanometric diameters to guide light as optical waveguide bend. We bend silica wires with scanning tunneling microscope probes under an optical microscope, and wire bends with bending radius smaller than 5 μm are obtained. Light from a He-Ne laser is launched into and guided through the wire bends, measured bending loss of a single bend is on the order of 1 dB. Brief introductions to the optical wave guiding and elastic bending properties of silica wires are also provided. Comparing with waveguide bends based on photonic bandgap structures, the waveguide bends from silica nanometric wires show advantages of simple structure, small overall size, easy fabrication and wide useful spectral range, which make them potentially useful in the miniaturization of photonic devices.

  16. Optical panel system including stackable waveguides

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeSanto, Leonard; Veligdan, James T.

    An optical panel system including stackable waveguides is provided. The optical panel system displays a projected light image and comprises a plurality of planar optical waveguides in a stacked state. The optical panel system further comprises a support system that aligns and supports the waveguides in the stacked state. In one embodiment, the support system comprises at least one rod, wherein each waveguide contains at least one hole, and wherein each rod is positioned through a corresponding hole in each waveguide. In another embodiment, the support system comprises at least two opposing edge structures having the waveguides positioned therebetween, whereinmore » each opposing edge structure contains a mating surface, wherein opposite edges of each waveguide contain mating surfaces which are complementary to the mating surfaces of the opposing edge structures, and wherein each mating surface of the opposing edge structures engages a corresponding complementary mating surface of the opposite edges of each waveguide.« less

  17. Optical panel system including stackable waveguides

    DOEpatents

    DeSanto, Leonard; Veligdan, James T.

    2007-03-06

    An optical panel system including stackable waveguides is provided. The optical panel system displays a projected light image and comprises a plurality of planar optical waveguides in a stacked state. The optical panel system further comprises a support system that aligns and supports the waveguides in the stacked state. In one embodiment, the support system comprises at least one rod, wherein each waveguide contains at least one hole, and wherein each rod is positioned through a corresponding hole in each waveguide. In another embodiment, the support system comprises at least two opposing edge structures having the waveguides positioned therebetween, wherein each opposing edge structure contains a mating surface, wherein opposite edges of each waveguide contain mating surfaces which are complementary to the mating surfaces of the opposing edge structures, and wherein each mating surface of the opposing edge structures engages a corresponding complementary mating surface of the opposite edges of each waveguide.

  18. Fabrication and Characterization of Thin Film Ion Implanted Composite Materials for Integrated Nonlinear Optical Devices

    NASA Technical Reports Server (NTRS)

    Sarkisov, S.; Curley, M.; Williams, E. K.; Wilkosz, A.; Ila, D.; Poker, D. B.; Hensley, D. K.; Smith, C.; Banks, C.; Penn, B.; hide

    1998-01-01

    Ion implantation has been shown to produce a high density of metal colloids within the layer regions of glasses and crystalline materials. The high-precipitate volume fraction and small size of metal nanoclusters formed leads to values for the third-order susceptibility much greater than those for metal doped solids. This has stimulated interest in use of ion implantation to make nonlinear optical materials. On the other side, LiNbO3 has proved to be a good material for optical waveguides produced by MeV ion implantation. Light confinement in these waveguides is produced by refractive index step difference between the implanted region and the bulk material. Implantation of LiNbO3 with MeV metal ions can therefore result into nonlinear optical waveguide structures with great potential in a variety of device applications. We describe linear and nonlinear optical properties of a waveguide structure in LiNbO3-based composite material produced by silver ion implantation in connection with mechanisms of its formation.

  19. Surface normal coupling to multiple-slot and cover-slotted silicon nanocrystalline waveguides and ring resonators

    NASA Astrophysics Data System (ADS)

    Covey, John; Chen, Ray T.

    2014-03-01

    Grating couplers are ideal for coupling into the tightly confined propagation modes of semiconductor waveguides. In addition, nonlinear optics has benefited from the sub-diffraction limit confinement of horizontal slot waveguides. By combining these two advancements, slot-based nonlinear optics with mode areas less than 0.02 μm2 can become as routine as twisting fiber connectors together. Surface normal fiber alignment to a chip is also highly desirable from time, cost, and manufacturing considerations. To meet these considerable design challenges, a custom genetic algorithm is created which, starting from purely random designs, creates a unique four stage grating coupler for two novel horizontal slot waveguide platforms. For horizontal multiple-slot waveguides filled with silicon nanocrystal, a theoretical fiber-towaveguide coupling efficiency of 68% is obtained. For thin silicon waveguides clad with optically active silicon nanocrystal, known as cover-slot waveguides, a theoretical fiber-to-waveguide coupling efficiency of 47% is obtained, and 1 dB and 3 dB theoretical bandwidths of 70 nm and 150 nm are obtained, respectively. Both waveguide platforms are fabricated from scratch, and their respective on-chip grating couplers are experimentally measured from a standard single mode fiber array that is mounted surface normally. The horizontal multiple-slot grating coupler achieved an experimental 60% coupling efficiency, and the horizontal cover-slot grating coupler achieved an experimental 38.7% coupling efficiency, with an extrapolated 1 dB bandwidth of 66 nm. This report demonstrates the promise of genetic algorithm-based design by reducing to practice the first large bandwidth vertical grating coupler to a novel silicon nanocrystal horizontal cover-slot waveguide.

  20. Polymer electro-optic waveguide devices: Low-loss etchless fabrication techniques and passive-to-active integration

    NASA Astrophysics Data System (ADS)

    Geary, Kevin

    The development of high-frequency polymer electro-optic modulators has seen steady and significant progress in recent years, yet applications of these promising materials to more complicated integrated optic structures and arrays of devices have been limited primarily due to high optical waveguide loss characteristics. This is unfortunate since a major advantage of polymers as photonic materials is their compatibility with photolithographic processing of large components. In this Dissertation, etchless waveguide writing techniques are presented in order to improve the overall optical insertion loss of electro-optic polymer waveguide devices. These techniques include poling-induced writing, stress-induced waveguide writing, and photobleaching. Using these waveguide writing mechanisms, we have demonstrated straight waveguides, phase modulators, Mach-Zehnder intensity modulators, variable optical attenuators, and multimode interference (MMI) power splitters, all with improved loss characteristics over their etched rib waveguide counterparts. Ultimately, the insertion loss of an integrated optic device is limited by the actual material loss of the core waveguide material. In this Dissertation, passive-to-active polymer waveguide transitions are proposed to circumvent this problem. These transitions are compact, in-plane, self-aligned, and require no tapering of any physical dimensions of the waveguides. By utilizing both the time-dependent and intensity-dependent photobleaching characteristics of electro-optic polymer materials, adiabatic refractive index tapers can be seamlessly coupled to in-plane butt couple transitions, resulting in losses as low as 0.1 dB per interface. By integrating passive polymer planar lightwave circuits with the high-speed phase shifting capability of electro-optic polymers, active wideband photonic devices of increased size and complexity can be realized. Optical fiber-to-device coupling can also result in significant contributions to the overall insertion loss of an integrated electro-optic polymer device. In this Dissertation, we leverage the photobleached refractive index taper component of our proposed passive-to-active polymer waveguide transitions in order to realize a two-dimensional optical mode transformer for improved overall fiber-to-device coupling of electro-optic polymer waveguide devices.

  1. Manufacturing of polymer optical waveguides using self-assembly effect on pre-conditioned 3D-thermoformed flexible substrates

    NASA Astrophysics Data System (ADS)

    Hoffmann, Gerd-Albert; Wolfer, Tim; Zeitler, Jochen; Franke, Jörg; Suttmann, Oliver; Overmeyer, Ludger

    2017-02-01

    Optical data communication is increasingly interesting for many applications in industrial processes. Therefore mass production is required to meet the requested price and lot sizes. Polymer optical waveguides show great promises to comply with price requirements while providing sufficient optical quality for short range data transmission. A high efficient fabrication technology using polymer materials could be able to create the essential backbone for 3D-optical data transmission in the future. The approach for high efficient fabrication technology of micro optics described in this paper is based on a self-assembly effect of fluids on preconditioned 3D-thermoformed polymer foils. Adjusting the surface energy on certain areas on the flexible substrate by flexographic printing mechanism is presented in this paper. With this technique conditioning lines made of silicone containing UV-varnish are printed on top of the foils and create gaps with the exposed substrate material in between. Subsequent fabrication processes are selected whether the preconditioned foil is coated with acrylate containing waveguide material prior or after the thermoforming process. Due to the different surface energy this material tends to dewet from the conditioning lines. It acts like regional barriers and sets the width of the arising waveguides. With this fabrication technology it is possible to produce multiple waveguides with a single coating process. The relevant printing process parameters that affect the quality of the generated waveguides are discussed and results of the produced waveguides with width ranging from 10 to 300 μm are shown.

  2. High-bandwidth and low-loss multimode polymer waveguides and waveguide components for high-speed board-level optical interconnects

    NASA Astrophysics Data System (ADS)

    Bamiedakis, N.; Chen, J.; Penty, R. V.; White, I. H.

    2016-03-01

    Multimode polymer waveguides are being increasingly considered for use in short-reach board-level optical interconnects as they exhibit favourable optical properties and allow direct integration onto standard PCBs with conventional methods of the electronics industry. Siloxane-based multimode waveguides have been demonstrated with excellent optical transmission performance, while a wide range of passive waveguide components that offer routing flexibility and enable the implementation of complex on-board interconnection architectures has been reported. In recent work, we have demonstrated that these polymer waveguides can exhibit very high bandwidth-length products in excess of 30 GHz×m despite their highly-multimoded nature, while it has been shown that even larger values of > 60 GHz×m can be achieved by adjusting their refractive index profile. Furthermore, the combination of refractive index engineering and launch conditioning schemes can ensure high bandwidth (> 100 GHz×m) and high coupling efficiency (<1 dB) with standard multimode fibre inputs with relatively large alignment tolerances (~17×15 μm2). In the work presented here, we investigate the effects of refractive index engineering on the performance of passive waveguide components (crossings, bends) and provide suitable design rules for their on-board use. It is shown that, depending on the interconnection layout and link requirements, appropriate choice of refractive index profile can provide enhanced component performance, ensuring low loss interconnection and adequate link bandwidth. The results highlight the strong potential of this versatile optical technology for the formation of high-performance board-level optical interconnects with high routing flexibility.

  3. Comparison of the efficiency control of mycotoxins by some optical immune biosensors

    NASA Astrophysics Data System (ADS)

    Slyshyk, N. F.; Starodub, N. F.

    2013-11-01

    It was compared the efficiency of patulin control at the application of such optical biosensors which were based on the surface plasmon resonance (SPR) and nano-porous silicon (sNPS). In last case the intensity of the immune reaction was registered by measuring level of chemiluminescence (ChL) or photocurrent of nPS. The sensitivity of this mycotoxin determination by first type of immune biosensor was 0.05-10 mg/L Approximately the same sensitivity as well as the overall time analysis were demonstrated by the immune biosensor based on the nPS too. Nevertheless, the last type of biosensor was simpler in technical aspect and the cost of analysis was cheapest. That is why, it was recommend the nPS based immune biosensor for wide screening application and SPR one for some additional control or verification of preliminary obtained results. In this article a special attention was given to condition of sample preparation for analysis, in particular, micotoxin extraction from potao and some juices. Moreover, it was compared the efficiency of the above mentioned immune biosensors with such traditional approach of mycotoxin determination as the ELISA-method. In the result of investigation and discussion of obtained data it was concluded that both type of the immune biosensors are able to fulfill modern practice demand in respect sensitivity, rapidity, simplicity and cheapness of analysis.

  4. Cross-linked polyimides for integrated optics

    NASA Astrophysics Data System (ADS)

    Singer, Kenneth D.; Kowalczyk, Tony C.; Nguyen, Hung D.; Beuhler, Allyson J.; Wargowski, David A.

    1997-01-01

    We have investigated a promising class of polyimide materials for both passive and active electro-optic devices, namely crosslinkable polyimides. These fluorinated polyimides are soluble in the imidized form and are both thermally and photo-crosslinkable leading to easy processability into waveguide structures and the possibility of stable electro-optic properties. We have fabricated channel and slab waveguides and investigated the mechanism of optical propagation loss using photothermal deflection spectroscopy and waveguide loss spectroscopy, and found the losses to arise from residual absorption due to the formation of charge transfer states. The absorption is inhibited by fluorination leading to propagation losses as low as 0.3 dB/cm in the near infrared. Because of the ability to photocrosslink, channel waveguides are fabricated using a simple wet-etch process. Channel waveguides so formed are observed to have no excess loss over slab structures. Solubility followed by thermal cross-linking allows the formation of multilayer structures. We have produced electro-optic polymers by doping with the nonlinear optical chromophores, DCM and DADC; and a process of concurrent poling and thermal crosslinking. Multilayer structures have been investigated and poling fields optimized in the active layer by doping the cladding with an anti-static agent. The high glass-transition temperature and cross-linking leads to very stable electro-optic properties. We are currently building electro-optic modulators based on these materials. Progress and results in this area also are reported.

  5. Photonic-chip-based all-optical ultra-wideband pulse generation via XPM and birefringence in a chalcogenide waveguide.

    PubMed

    Tan, Kang; Marpaung, David; Pant, Ravi; Gao, Feng; Li, Enbang; Wang, Jian; Choi, Duk-Yong; Madden, Steve; Luther-Davies, Barry; Sun, Junqiang; Eggleton, Benjamin J

    2013-01-28

    We report a photonic-chip-based scheme for all-optical ultra-wideband (UWB) pulse generation using a novel all-optical differentiator that exploits cross-phase modulation and birefringence in an As₂S₃ chalcogenide rib waveguide. Polarity-switchable UWB monocycles and doublets were simultaneously obtained with single optical carrier operation. Moreover, transmission over 40-km fiber of the generated UWB doublets is demonstrated with good dispersion tolerance. These results indicate that the proposed approach has potential applications in multi-shape, multi-modulation and long-distance UWB-over-fiber communication systems.

  6. Precision Laser Development for Interferometric Space Missions NGO, SGO, and GRACE Follow-On

    NASA Technical Reports Server (NTRS)

    Numata, Kenji; Camp, Jordan

    2011-01-01

    Optical fiber and semiconductor laser technologies have evolved dramatically over the last decade due to the increased demands from optical communications. We are developing a laser (master oscillator) and optical amplifier based on those technologies for interferometric space missions, including the gravitational-wave missions NGO/SGO (formerly LISA) and the climate monitoring mission GRACE Follow-On, by fully utilizing the matured wave-guided optics technologies. In space, where simpler and more reliable system is preferred, the wave-guided components are advantageous over bulk, crystal-based, free-space laser, such as NPRO (Nonplanar Ring Oscillator) and bulk-crystal amplifier.

  7. Biosensors for hepatitis B virus detection.

    PubMed

    Yao, Chun-Yan; Fu, Wei-Ling

    2014-09-21

    A biosensor is an analytical device used for the detection of analytes, which combines a biological component with a physicochemical detector. Recently, an increasing number of biosensors have been used in clinical research, for example, the blood glucose biosensor. This review focuses on the current state of biosensor research with respect to efficient, specific and rapid detection of hepatitis B virus (HBV). The biosensors developed based on different techniques, including optical methods (e.g., surface plasmon resonance), acoustic wave technologies (e.g., quartz crystal microbalance), electrochemistry (amperometry, voltammetry and impedance) and novel nanotechnology, are also discussed.

  8. Flexible polymeric rib waveguide with self-align couplers system

    PubMed Central

    Huang, Cheng-Sheng; Wang, Wei-Chih

    2011-01-01

    The authors report a polymeric based rib waveguide with U shape self-align fiber couplers system using a simple micromolding process with SU8 as a molding material and polydimethysiloxane as a waveguide material. The material is used for its good optical transparency, low surface tension, biocompatibility, and durability. Furthermore, the material is highly formable. This unique fabrication molding technique provides a means of keeping the material and manufacturing costs to a minimum. The self-align fiber couplers system also proves a fast and simple means of light coupling. The flexible nature of the waveguide material makes this process ideal for a potential wearable optical sensor. PMID:22171151

  9. InP-based monolithically integrated 1310/1550nm diplexer/triplexer

    NASA Astrophysics Data System (ADS)

    Silfvenius, C.; Swillo, M.; Claesson, J.; Forsberg, E.; Akram, N.; Chacinski, M.; Thylén, L.

    2008-11-01

    Multiple streams of high definition television (HDTV) and improved home-working infrastructure are currently driving forces for potential fiber to the home (FTTH) customers [1]. There is an interest to reduce the cost and physical size of the FTTH equipment. The current fabrication methods have reached a cost minimum. We have addressed the costchallenge by developing 1310/(1490)/1550nm bidirectional diplexers, by monolithic seamless integration of lasers, photodiodes and wavelength division multiplexing (WDM) couplers into one single InP-based device. A 250nm wide optical gain profile covers the spectrum from 1310 to 1550nm and is the principal building block. The device fabrication is basically based on the established configuration of using split-contacts on continuos waveguides. Optical and electrical cross-talks are further addressed by using a Y-configuration to physically separate the components from each other and avoid inline configurations such as when the incoming signal travels through the laser component or vice versa. By the eliminated butt-joint interfaces which can reflect light between components or be a current leakage path and by leaving optically absorbing (unpumped active) material to surround the components to absorb spontaneous emission and nonintentional reflections the devices are optically and electrically isolated from each other. Ridge waveguides (RWG) form the waveguides and which also maintain the absorbing material between them. The WDM functionality is designed for a large optical bandwidth complying with the wide spectral range in FTTH applications and also reducing the polarization dependence of the WDM-coupler. Lasing is achieved by forming facet-free, λ/4-shifted, DFB (distributed feedback laser) lasers emitting directly into the waveguide. The photodiodes are waveguide photo-diodes (WGPD). Our seamless technology is also able to array the single channel diplexers to 4 to 12 channel diplexer arrays with 250μm fiber port waveguide spacing to comply with fiber optic ribbons. This is an important feature in central office applications were small physical space is important.

  10. Towards a subcutaneous optical biosensor based on thermally hydrocarbonised porous silicon.

    PubMed

    Tong, Wing Yin; Sweetman, Martin J; Marzouk, Ezzat R; Fraser, Cara; Kuchel, Tim; Voelcker, Nicolas H

    2016-01-01

    Advanced biosensors in future medicine hinge on the evolvement of biomaterials. Porous silicon (pSi), a generally biodegradable and biocompatible material that can be fabricated to include environment-responsive optical characteristics, is an excellent candidate for in vivo biosensors. However, the feasibility of using this material as a subcutaneously implanted optical biosensor has never been demonstrated. Here, we investigated the stability and biocompatibility of a thermally-hydrocarbonised (THC) pSi optical rugate filter, and demonstrated its optical functionality in vitro and in vivo. We first compared pSi films with different surface chemistries and observed that the material was cytotoxic despite the outstanding stability of the THC pSi films. We then showed that the cytotoxicity correlates with reactive oxygen species levels, which could be mitigated by pre-incubation of THC pSi (PITHC pSi). PITHC pSi facilitates normal cellular phenotypes and is biocompatible in vivo. Importantly, the material also possesses optical properties capable of responding to microenvironmental changes that are readable non-invasively in cell culture and subcutaneous settings. Collectively, we demonstrate, for the first time, that PITHC pSi rugate filters are both biocompatible and optically functional for lab-on-a-chip and subcutaneous biosensing scenarios. We believe that this study will deepen our understanding of cell-pSi interactions and foster the development of implantable biosensors. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Highly stable and low loss electro-optic polymer waveguides for high speed microring modulators using photodefinition

    NASA Astrophysics Data System (ADS)

    Balakrishnan, M.; Diemeer, M. B. J.; Driessen, A.; Faccini, M.; Verboom, W.; Reinhoudt, D. N.; Leinse, A.

    2006-02-01

    Different electro-optic polymer systems are analyzed with respect to their electro-optic activity, glass transition temperature (T g) and photodefinable properties. The polymers tested are polysulfone (PS) and SU8. The electro-optic chromophore, tricyanovinylidenediphenylaminobenzene (TCVDPA), which was reported to have a high photochemical stability 1 has been employed in the current work. Tert-butyl-TCVDPA, having bulky side groups, was synthesized and a doubling of the electro-optic coefficient (r33) compared to the unmodified TCVDPA was shown. A microring resonator design was made based on the PS-TCVDPA system. SU8 (passive) and TCVDPA (active) channel waveguides were fabricated by the photodefinition technique and the passive waveguide losses were measured to be 5 dB/cm at 1550 nm.

  12. Direct write fabrication of waveguides and interconnects for optical printed wiring boards

    NASA Astrophysics Data System (ADS)

    Dingeldein, Joseph C.

    Current copper based circuit technology is becoming a limiting factor in high speed data transfer applications as processors are improving at a faster rate than are developments to increase on board data transfer. One solution is to utilize optical waveguide technology to overcome these bandwidth and loss restrictions. The use of this technology virtually eliminates the heat and cross-talk loss seen in copper circuitry, while also operating at a higher bandwidth. Transitioning current fabrication techniques from small scale laboratory environments to large scale manufacturing presents significant challenges. Optical-to-electrical connections and out-of-plane coupling are significant hurdles in the advancement of optical interconnects. The main goals of this research are the development of direct write material deposition and patterning tools for the fabrication of waveguide systems on large substrates, and the development of out-of-plane coupler components compatible with standard fiber optic cabling. Combining these elements with standard printed circuit boards allows for the fabrication of fully functional optical-electrical-printed-wiring-boards (OEPWBs). A direct dispense tool was designed, assembled, and characterized for the repeatable dispensing of blanket waveguide layers over a range of thicknesses (25-225 μm), eliminating waste material and affording the ability to utilize large substrates. This tool was used to directly dispense multimode waveguide cores which required no UV definition or development. These cores had circular cross sections and were comparable in optical performance to lithographically fabricated square waveguides. Laser direct writing is a non-contact process that allows for the dynamic UV patterning of waveguide material on large substrates, eliminating the need for high resolution masks. A laser direct write tool was designed, assembled, and characterized for direct write patterning waveguides that were comparable in quality to those produced using standard lithographic practices (0.047 dB/cm loss for laser written waveguides compared to 0.043 dB/cm for lithographic waveguides). Straight waveguides, and waveguide turns were patterned at multimode and single mode sizes, and the process was characterized and documented. Support structures such as angled reflectors and vertical posts were produced, showing the versatility of the laser direct write tool. Commercially available components were implanted into the optical layer for out-of-plane routing of the optical signals. These devices featured spherical lenses on the input and output sides of a total internal reflection (TIR) mirror, as well as alignment pins compatible with standard MT design. Fully functional OEPWBs were fabricated featuring input and output out-of-plane optical signal routing with total optical losses not exceeding 10 dB. These prototypes survived thermal cycling (-40°C to 85°C) and humidity exposure (95±4% humidity), showing minimal degradation in optical performance. Operational failure occurred after environmental aging life testing at 110°C for 216 hours.

  13. Advantages and application of label-free detection assays in drug screening.

    PubMed

    Cunningham, Brian T; Laing, Lance G

    2008-08-01

    Adoption is accelerating for a new family of label-free optical biosensors incorporated into standard format microplates owing to their ability to enable highly sensitive detection of small molecules, proteins and cells for high-throughput drug discovery applications. Label-free approaches are displacing other detection technologies owing to their ability to provide simple assay procedures for hit finding/validation, accessing difficult target classes, screening the interaction of cells with drugs and analyzing the affinity of small molecule inhibitors to target proteins. This review describes several new drug discovery applications that are under development for microplate-based photonic crystal optical biosensors and the key issues that will drive adoption of the technology. Microplate-based optical biosensors are enabling a variety of cell-based assays, inhibition assays, protein-protein binding assays and protein-small molecule binding assays to be performed with high-throughput and high sensitivity.

  14. Optical NOR logic gate design on square lattice photonic crystal platform

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D’souza, Nirmala Maria, E-mail: nirmala@cukerala.ac.in; Mathew, Vincent, E-mail: vincent@cukerala.ac.in

    We numerically demonstrate a new configuration of all-optical NOR logic gate with square lattice photonic crystal (PhC) waveguide using finite difference time domain (FDTD) method. The logic operations are based on interference effect of optical waves. We have determined the operating frequency range by calculating the band structure for a perfectly periodic PhC using plane wave expansion (PWE) method. Response time of this logic gate is 1.98 ps and it can be operated with speed about 513 GB/s. The proposed device consists of four linear waveguides and a square ring resonator waveguides on PhC platform.

  15. A novel graphene oxide-polyimide as optical waveguide material: Synthesis and thermo-optic switch properties

    NASA Astrophysics Data System (ADS)

    Cao, Tianlin; Zhao, Fanyu; Da, Zulin; Qiu, Fengxian; Yang, Dongya; Guan, Yijun; Cao, Guorong; Zhao, Zerun; Li, Jiaxin; Guo, Xiaotong

    2016-10-01

    In this work, a novel graphene oxide-polyimide (GOPI) as optical waveguide material was prepared. The structure, mechanical, thermal property and morphology of the GOPI was characterized by using fourier transform infrared, UV-visible spectroscopy, near-infrared spectrum, thermogravimetric analysis, differential scanning calorimetry, scanning electron microscope and transmission electron microscopy. The thermo-optic coefficients (dn/dT) are -9.16 × 10-4 (532 nm), -7.56 × 10-4 (650 nm) and -4.82 × 10-4 (850 nm) °C-1, respectively. Based on the thermo-optic effect of prepared GOPI as waveguide material, a Y-branch with branching angle of 0.143° and Mach-Zehnder thermo-optic switches were designed. Using finite difference beam propagation method (FD-BPM) method, the simulation results such as power consumptions and response times of two different thermo-optic switches were obtained.

  16. Monolithically integrated solid state laser and waveguide using spin-on glass

    DOEpatents

    Ashby, C.I.H.; Hohimer, J.P.; Neal, D.R.; Vawter, G.A.

    1995-10-31

    A monolithically integrated photonic circuit is disclosed combining a semiconductor source of excitation light with an optically active waveguide formed on the substrate. The optically active waveguide is preferably formed of a spin-on glass to which are added optically active materials which can enable lasing action, optical amplification, optical loss, or frequency conversion in the waveguide, depending upon the added material. 4 figs.

  17. Optical interconnects based on VCSELs and low-loss silicon photonics

    NASA Astrophysics Data System (ADS)

    Aalto, Timo; Harjanne, Mikko; Karppinen, Mikko; Cherchi, Matteo; Sitomaniemi, Aila; Ollila, Jyrki; Malacarne, Antonio; Neumeyr, Christian

    2018-02-01

    Silicon photonics with micron-scale Si waveguides offers most of the benefits of submicron SOI technology while avoiding most of its limitations. In particular, thick silicon-on-insulator (SOI) waveguides offer 0.1 dB/cm propagation loss, polarization independency, broadband single-mode (SM) operation from 1.2 to >4 µm wavelength and ability to transmit high optical powers (>1 W). Here we describe the feasibility of Thick-SOI technology for advanced optical interconnects. With 12 μm SOI waveguides we demonstrate efficient coupling between standard single-mode fibers, vertical-cavity surface-emitting lasers (VCSELs) and photodetectors (PDs), as well as wavelength multiplexing in small footprint. Discrete VCSELs and PDs already support 28 Gb/s on-off keying (OOK), which shows a path towards 50-100 Gb/s bandwidth per wavelength by using more advanced modulation formats like PAM4. Directly modulated VCSELs enable very power-efficient optical interconnects for up to 40 km distance. Furthermore, with 3 μm SOI waveguides we demonstrate extremely dense and low-loss integration of numerous optical functions, such as multiplexers, filters, switches and delay lines. Also polarization independent and athermal operation is demonstrated. The latter is achieved by using short polymer waveguides to compensate for the thermo-optic effect in silicon. New concepts for isolator integration and polarization rotation are also explained.

  18. Strongly-guided indium phosphide/indium gallium arsenic phosphide Mach-Zehnder modulator for optical communications

    NASA Astrophysics Data System (ADS)

    Betty, Ian Brian

    2006-12-01

    The development of strongly-guided InP/In1-x GaxAsyP 1-y based Mach-Zehnder optical modulators for 10Gb/s telecommunications is detailed. The modulators have insertion losses including coupling as low as 4.5dB, due to the incorporation of monolithically integrated optical mode spot-size converters (SSC's). The modulators are optimized to produce system performance that is independent of optical coupling alignment and for wavelength operation between 1525nm and 1565nm. A negatively chirped Mach-Zehnder modulator design is demonstrated, giving optimal dispersion-limited reach for 10Gb/s ON/OFF-keying modulation. It is shown that the optical system performance for this design can be determined from purely DC based optical measurements. A Mach-Zehnder modulator design invoking nearly no transient frequency shifts under intensity modulation is also presented, for the first time, using phase-shifter implementations based on the Quantum-Confined-Stark-Effect (QCSE). The performance impact on the modulator from the higher-order vertical and lateral waveguide modes found in strongly-guided waveguides has been determined. The impact of these higher-order modes has been minimized using the design of the waveguide bends, MMI structures, and doping profiles. The fabrication process and optical design for the spot-size mode converters are also thoroughly explored. The SSC structures are based on butt-joined vertically tapered passive waveguide cores within laterally flared strongly-guided ridges, making them compatible with any strong-guiding waveguide structure. The flexibility of the SSC process is demonstrated by the superior performance it has also enabled in a 40Gb/s electro-absorption modulator. The presented electro-absorption modulator has 3.6dB fiber-to-fiber insertion loss, polarization dependent loss (PDL) of only 0.3dB over 15dB extinction, and low absolute chirp (|alpha H| < 0.6) over the full dynamic range.

  19. Buried anti resonant reflecting optical waveguide based on porous silicon material for an integrated Mach Zehnder structure

    NASA Astrophysics Data System (ADS)

    Hiraoui, M.; Guendouz, M.; Lorrain, N.; Haji, L.; Oueslati, M.

    2012-11-01

    A buried anti resonant reflecting optical waveguide for an integrated Mach Zehnder structure based on porous silicon material is achieved using a classical photolithography process. Three distinct porous silicon layers are then elaborated in a single step, by varying the porosity (thus the refractive index) and the thickness while respecting the anti-resonance conditions. Simulations and experimental results clearly show the antiresonant character of the buried waveguides. Significant variation of the reflectance and light propagation with different behavior depending on the polarization and the Mach Zehnder dimensions is obtained. Finally, we confirm the feasibility of this structure for sensing applications.

  20. 100 GHz pulse waveform measurement based on electro-optic sampling

    NASA Astrophysics Data System (ADS)

    Feng, Zhigang; Zhao, Kejia; Yang, Zhijun; Miao, Jingyuan; Chen, He

    2018-05-01

    We present an ultrafast pulse waveform measurement system based on an electro-optic sampling technique at 1560 nm and prepare LiTaO3-based electro-optic modulators with a coplanar waveguide structure. The transmission and reflection characteristics of electrical pulses on a coplanar waveguide terminated with an open circuit and a resistor are investigated by analyzing the corresponding time-domain pulse waveforms. We measure the output electrical pulse waveform of a 100 GHz photodiode and the obtained rise times of the impulse and step responses are 2.5 and 3.4 ps, respectively.

  1. Waveguides in Thin Film Polymeric Materials

    NASA Technical Reports Server (NTRS)

    Sakisov, Sergey; Abdeldayem, Hossin; Venkateswarlu, Putcha; Teague, Zedric

    1996-01-01

    Results on the fabrication of integrated optical components in polymeric materials using photo printing methods will be presented. Optical waveguides were fabricated by spin coating preoxidized silicon wafers with organic dye/polymer solution followed by soft baking. The waveguide modes were studied using prism coupling technique. Propagation losses were measured by collecting light scattered from the trace of a propagation mode by either scanning photodetector or CCD camera. We observed the formation of graded index waveguides in photosensitive polyimides after exposure of UV light from a mercury arc lamp. By using a theoretical model, an index profile was reconstructed which is in agreement with the profile reconstructed by the Wentzel-Kramers-Brillouin calculation technique using a modal spectrum of the waveguides. Proposed mechanism for the formation of the graded index includes photocrosslinking followed by UV curing accompanied with optical absorption increase. We also developed the prototype of a novel single-arm double-mode interferometric sensor based on our waveguides. It demonstrates high sensitivity to the chance of ambient temperature. The device can find possible applications in aeropropulsion control systems.

  2. Biosensing with Förster Resonance Energy Transfer Coupling between Fluorophores and Nanocarbon Allotropes

    PubMed Central

    Ding, Shaowei; Cargill, Allison A.; Das, Suprem R.; Medintz, Igor L.; Claussen, Jonathan C.

    2015-01-01

    Nanocarbon allotropes (NCAs), including zero-dimensional carbon dots (CDs), one-dimensional carbon nanotubes (CNTs) and two-dimensional graphene, exhibit exceptional material properties, such as unique electrical/thermal conductivity, biocompatibility and high quenching efficiency, that make them well suited for both electrical/electrochemical and optical sensors/biosensors alike. In particular, these material properties have been exploited to significantly enhance the transduction of biorecognition events in fluorescence-based biosensing involving Förster resonant energy transfer (FRET). This review analyzes current advances in sensors and biosensors that utilize graphene, CNTs or CDs as the platform in optical sensors and biosensors. Widely utilized synthesis/fabrication techniques, intrinsic material properties and current research examples of such nanocarbon, FRET-based sensors/biosensors are illustrated. The future outlook and challenges for the research field are also detailed. PMID:26110411

  3. High intersubband absorption in long-wave quantum well infrared photodetector based on waveguide resonance

    NASA Astrophysics Data System (ADS)

    Zheng, Yuanliao; Chen, Pingping; Ding, Jiayi; Yang, Heming; Nie, Xiaofei; Zhou, Xiaohao; Chen, Xiaoshuang; Lu, Wei

    2018-06-01

    A hybrid structure consisting of periodic gold stripes and an overlaying gold film has been proposed as the optical coupler of a long-wave quantum well infrared photodetector. Absorption spectra and field distributions of the structure at back-side normal incidence are calculated by the finite difference time-domain method. The results indicate that the intersubband absorption can be greatly enhanced based on the waveguide resonance as well as the surface plasmon polariton (SPP) mode. With the optimized structural parameters of the periodic gold stripes, the maximal intersubband absorption can exceed 80%, which is much higher than the SPP-enhanced intersubband absorption (<50%) and about 6 times the one of the standard device. The relationship between the structural parameters and the waveguide resonant wavelength is derived. Other advantages of the efficient optical coupling based on waveguide resonance are also discussed.

  4. A large response range reflectometric urea biosensor made from silica-gel nanoparticles.

    PubMed

    Alqasaimeh, Muawia; Heng, Lee Yook; Ahmad, Musa; Raj, A S Santhana; Ling, Tan Ling

    2014-07-22

    A new silica-gel nanospheres (SiO2NPs) composition was formulated, followed by biochemical surface functionalization to examine its potential in urea biosensor development. The SiO2NPs were basically synthesized based on sol-gel chemistry using a modified Stober method. The SiO2NPs surfaces were modified with amine (-NH2) functional groups for urease immobilization in the presence of glutaric acid (GA) cross-linker. The chromoionophore pH-sensitive dye ETH 5294 was physically adsorbed on the functionalized SiO2NPs as pH transducer. The immobilized urease determined urea concentration reflectometrically based on the colour change of the immobilized chromoionophore as a result of the enzymatic hydrolysis of urea. The pH changes on the biosensor due to the catalytic enzyme reaction of immobilized urease were found to correlate with the urea concentrations over a linear response range of 50-500 mM (R2 = 0.96) with a detection limit of 10 mM urea. The biosensor response time was 9 min with reproducibility of less than 10% relative standard deviation (RSD). This optical urea biosensor did not show interferences by Na+, K+, Mg2+ and NH4+ ions. The biosensor performance has been validated using urine samples in comparison with a non-enzymatic method based on the use of p-dimethylaminobenzaldehyde (DMAB) reagent and demonstrated a good correlation between the two different methods (R2 = 0.996 and regression slope of 1.0307). The SiO2NPs-based reflectometric urea biosensor showed improved dynamic linear response range when compared to other nanoparticle-based optical urea biosensors.

  5. Low-loss curved subwavelength grating waveguide based on index engineering

    NASA Astrophysics Data System (ADS)

    Wang, Zheng; Xu, Xiaochuan; Fan, D. L.; Wang, Yaoguo; Chen, Ray T.

    2016-03-01

    Subwavelength grating (SWG) waveguide is an intriguing alternative to conventional optical waveguides due to its freedom to tune a few important waveguide properties such as dispersion and refractive index. Devices based on SWG waveguide have demonstrated impressive performances compared to those of conventional waveguides. However, the large loss of SWG waveguide bends jeopardizes their applications in integrated photonics circuits. In this work, we propose that a predistorted refractive index distribution in SWG waveguide bends can effectively decrease the mode mismatch noise and radiation loss simultaneously, and thus significantly reduce the bend loss. Here, we achieved the pre-distortion refractive index distribution by using trapezoidal silicon pillars. This geometry tuning approach is numerically optimized and experimentally demonstrated. The average insertion loss of a 5 μm SWG waveguide bend can be reduced drastically from 5.58 dB to 1.37 dB per 90° bend for quasi-TE polarization. In the future, the proposed approach can be readily adopted to enhance performance of an array of SWG waveguide-based photonics devices.

  6. pH-based fiber optic biosensors for use in clinical and biotechnological applications

    NASA Astrophysics Data System (ADS)

    Mueller, Cord; Hitzmann, Bernd; Schubert, Florian; Scheper, Thomas

    1995-05-01

    The development of pH-based fiber optic biosensors and their uses in clinical and biotechnological applications are described. Based on a pH-sensitive optode, different biosensors for urea, penicillin, glucose and creatinine were developed. A multichannel modular fluorimeter was used to measure signals from up to three optodes simultaneously. The pH value and the buffer capacity are critical factors for biosensors based on pH probes and influence the biosensor signal. A flow injection analysis (FIA) system is used to eliminate the latter influences. With this integrated system, samples can be analyzed sequentially by the injection of a defined volume of each sample into a continuously flowing buffer stream that transports the samples to the sensors. The complex signal is transformed and analyzed by a computer system. Characteristic features of the FIA peak give information about the buffer capacity in the solution. With the help of intelligent computing (neural networks) it is possible to recognize these features and relate them to the respective buffer capacity to obtain more accurate values. Various applications of these biosensors are discussed. The pH optode is also used to monitor enzymatic reactions in non aqueous solvents. In this case the production of acetic acid can be detected on line.

  7. Integrated optical devices based on sol – gel waveguides using the temperature dependence of the effective refractive index

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pavlov, S V; Trofimov, N S; Chekhlova, T K

    2014-07-31

    A possibility of designing optical waveguide devices based on sol – gel SiO{sub 2} – TiO{sub 2} films using the temperature dependence of the effective refractive index is shown. The dependences of the device characteristics on the parameters of the film and opticalsystem elements are analysed. The operation of a temperature recorder and a temperature limiter with a resolution of 0.6 K mm{sup -1} is demonstrated. The film and output-prism parameters are optimised. (fibreoptic and nonlinear-optic devices)

  8. Organization of the Integrated Photonics Topical Meeting Held in Victoria, British Columbia on 30 March-1 April 1998. Technical Digest Series. Volume 4. Postconference Edition

    DTIC Science & Technology

    1999-03-22

    amplifiers fabricated on Si substrates by co- sputtering, (p. 27) 11:30am IMC3 ■ Birefrlngent oxidized porous silicon-based optical waveguides, Yu. N...that integrated optical waveguides based on oxidized porous silicon have a relatively large birefringence. As a result, the modes of both... Membrane microresonator lasers with 2-D photonic bandgap crystal mirrors for compact in- plane optics, B. D’Urso, O. Painter, A. Yariv, A. Scherer

  9. Tunable all-optical plasmonic rectifier in nanoscale metal-insulator-metal waveguides.

    PubMed

    Xu, Yi; Wang, Xiaomeng; Deng, Haidong; Guo, Kangxian

    2014-10-15

    We propose a tunable all-optical plasmonic rectifier based on the nonlinear Fano resonance in a metal-insulator-metal plasmonic waveguide and cavities coupling system. We develop a theoretical model based on the temporal coupled-mode theory to study the device physics of the nanoscale rectifier. We further demonstrate via the finite difference time domain numerical experiment that our idea can be realized in a plasmonic system with an ultracompact size of ~120×800  nm². The tunable plasmonic rectifier could facilitate the all-optical signal processing in nanoscale.

  10. Flexible polymer waveguides for light-activated therapy (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Kim, Moonseok; Kwok, Sheldon J. J.; Lin, Harvey H.; Lee, Dong Hee; Yun, Seok Hyun

    2017-02-01

    Conventional light-activated therapies, such as photodynamic therapy (PDT), photochemical tissue bonding (PTB), collagen crosslinking (CXL), low-level light therapy (LLLT), and antimicrobial therapy utilize external light sources and light propagation through free space, limiting treatment to accessible and superficial areas of the body. Recent progress has been made in developing biocompatible polymer waveguides to enhance light delivery to deep tissues. To further expand clinical utility, waveguides should be flexible and tough enough to enable use in anatomically difficult-to-reach regions, while having the requisite optical properties to achieve uniform and efficient illumination of the target area. Here, we present a new class of flexible polymer waveguides optimized for uniform light extraction into tissues. Our slab waveguides comprise two designs: first, a flexible polydimethylsiloxane (PDMS) based elastomer for CXL, and second, a tough polyacrylamide and alginate hydrogel for large-area phototherapies. Our waveguides are optically transparent in the visible wavelengths (400-750 nm) and a multimode fiber is used to couple light into the waveguide. We characterized the light propagation through the waveguides and light extraction into tissue, and validated our results with optical simulation. By changing the thickness and scattering properties, uniform light extraction through the length of the waveguide could be achieved. We demonstrate proof-of-concept scleral photo-crosslinking of an ex vivo porcine eyeball for prevention of myopia.

  11. Integrated optical gyroscope using active Long-range surface plasmon-polariton waveguide resonator

    PubMed Central

    Zhang, Tong; Qian, Guang; Wang, Yang-Yang; Xue, Xiao-Jun; Shan, Feng; Li, Ruo-Zhou; Wu, Jing-Yuan; Zhang, Xiao-Yang

    2014-01-01

    Optical gyroscopes with high sensitivity are important rotation sensors for inertial navigation systems. Here, we present the concept of integrated resonant optical gyroscope constructed by active long-range surface plasmon-polariton (LRSPP) waveguide resonator. In this gyroscope, LRSPP waveguide doped gain medium is pumped to compensate the propagation loss, which has lower pump noise than that of conventional optical waveguide. Peculiar properties of single-polarization of LRSPP waveguide have been found to significantly reduce the polarization error. The metal layer of LRSPP waveguide is electro-optical multiplexed for suppression of reciprocal noises. It shows a limited sensitivity of ~10−4 deg/h, and a maximum zero drift which is 4 orders of magnitude lower than that constructed by conventional single-mode waveguide. PMID:24458281

  12. Infiltrated photonic crystal cavity as a highly sensitive platform for glucose concentration detection

    NASA Astrophysics Data System (ADS)

    Arafa, Safia; Bouchemat, Mohamed; Bouchemat, Touraya; Benmerkhi, Ahlem; Hocini, Abdesselam

    2017-02-01

    A Bio-sensing platform based on an infiltrated photonic crystal ring shaped holes cavity-coupled waveguide system is proposed for glucose concentration detection. Considering silicon-on-insulator (SOI) technology, it has been demonstrated that the ring shaped holes configuration provides an excellent optical confinement within the cavity region, which further enhances the light-matter interactions at the precise location of the analyte medium. Thus, the sensitivity and the quality factor (Q) can be significantly improved. The transmission characteristics of light in the biosensor under different refractive indices that correspond to the change in the analyte glucose concentration are analyzed by performing finite-difference time-domain (FDTD) simulations. Accordingly, an improved sensitivity of 462 nm/RIU and a Q factor as high as 1.11х105 have been achieved, resulting in a detection limit of 3.03х10-6 RIU. Such combination of attributes makes the designed structure a promising element for performing label-free biosensing in medical diagnosis and environmental monitoring.

  13. Detection of Lipomannan in Cattle Infected with Bovine Tuberculosis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vu, Dung M.; Sakamuri, Rama M.; Waters, W. Ray

    Early and rapid detection of bovine tuberculosis (bTB) is critical to controlling the spread of this disease in cattle and other animals. Here in this study, we demonstrate the development of an immunoassay for the direct detection of the bovine bTB biomarker, lipomannan (LM) in serum using a waveguide-based optical biosensor. We apply an ultra-sensitive detection strategy developed by our team, termed lipoprotein capture, that exploits the pull-down of high-density lipoprotein (HDL) nanodiscs from cattle blood that allows for the recovery and detection of associated LM. We also profile the change in the expression of these TB biomarkers as amore » function of time from a small set of samples collected from studies of bovine TB-infected cattle. Lastly, we demonstrate for the first time the direct detection of bovine LM in serum, and clearly show that the biomarker is expressed in detectable concentrations during the entire course of the infection.« less

  14. Detection of Lipomannan in Cattle Infected with Bovine Tuberculosis

    DOE PAGES

    Vu, Dung M.; Sakamuri, Rama M.; Waters, W. Ray; ...

    2017-04-10

    Early and rapid detection of bovine tuberculosis (bTB) is critical to controlling the spread of this disease in cattle and other animals. Here in this study, we demonstrate the development of an immunoassay for the direct detection of the bovine bTB biomarker, lipomannan (LM) in serum using a waveguide-based optical biosensor. We apply an ultra-sensitive detection strategy developed by our team, termed lipoprotein capture, that exploits the pull-down of high-density lipoprotein (HDL) nanodiscs from cattle blood that allows for the recovery and detection of associated LM. We also profile the change in the expression of these TB biomarkers as amore » function of time from a small set of samples collected from studies of bovine TB-infected cattle. Lastly, we demonstrate for the first time the direct detection of bovine LM in serum, and clearly show that the biomarker is expressed in detectable concentrations during the entire course of the infection.« less

  15. Prediction of the limit of detection of an optical resonant reflection biosensor.

    PubMed

    Hong, Jongcheol; Kim, Kyung-Hyun; Shin, Jae-Heon; Huh, Chul; Sung, Gun Yong

    2007-07-09

    A prediction of the limit of detection of an optical resonant reflection biosensor is presented. An optical resonant reflection biosensor using a guided-mode resonance filter is one of the most promising label-free optical immunosensors due to a sharp reflectance peak and a high sensitivity to the changes of optical path length. We have simulated this type of biosensor using rigorous coupled wave theory to calculate the limit of detection of the thickness of the target protein layer. Theoretically, our biosensor has an estimated ability to detect thickness change approximately the size of typical antigen proteins. We have also investigated the effects of the absorption and divergence of the incident light on the detection ability of the biosensor.

  16. Cholesterol biosensor based on a plastic optical fibre with sol-gel: structural analysis and sensing properties

    NASA Astrophysics Data System (ADS)

    Razo-Medina, D. A.; Trejo-Durán, M.; Alvarado-Méndez, E.

    2018-02-01

    In this paper, we report the design and characterization of an optical fibre cholesterol biosensor by using sol-gel immobilization technique. The cholesterol enzyme is encapsulated inside of the sol-gel film onto an end of a plastic optical fibre. Two film deposition methods (Dip-Coating and Immersion) were studied. The morphology analysis and sensing properties permit us to determine the best film deposition to sense cholesterol concentration. The range of measured is 4.4-5.2 mM in real time and our results were validated by comparing them with other previously published results. The biosensor is portable, simple cheap, and easy to use.

  17. Design challenges of EO polymer based leaky waveguide deflector for 40 Gs/s all-optical analog-to-digital converters

    NASA Astrophysics Data System (ADS)

    Hadjloum, Massinissa; El Gibari, Mohammed; Li, Hongwu; Daryoush, Afshin S.

    2016-08-01

    Design challenges and performance optimization of an all-optical analog-to-digital converter (AOADC) is presented here. The paper addresses both microwave and optical design of a leaky waveguide optical deflector using electro-optic (E-O) polymer. The optical deflector converts magnitude variation of the applied RF voltage into variation of deflection angle out of a leaky waveguide optical beam using the linear E-O effect (Pockels effect) as part of the E-O polymer based optical waveguide. This variation of deflection angle as result of the applied RF signal is then quantized using optical windows followed by an array of high-speed photodetectors. We optimized the leakage coefficient of the leaky waveguide and its physical length to achieve the best trade-off between bandwidth and the deflected optical beam resolution, by improving the phase velocity matching between lightwave and microwave on one hand and using pre-emphasis technique to compensate for the RF signal attenuation on the other hand. In addition, for ease of access from both optical and RF perspective, a via-hole less broad bandwidth transition is designed between coplanar pads and coupled microstrip (CPW-CMS) driving electrodes. With the best reported E-O coefficient of 350 pm/V, the designed E-O deflector should allow an AOADC operating over 44 giga-samples-per-seconds with an estimated effective resolution of 6.5 bits on RF signals with Nyquist bandwidth of 22 GHz. The overall DC power consumption of all components used in this AOADC is of order of 4 W and is dominated by power consumption in the power amplifier to generate a 20 V RF voltage in 50 Ohm system. A higher sampling rate can be achieved at similar bits of resolution by interleaving a number of this elementary AOADC at the expense of a higher power consumption.

  18. Design of ultra-broadband terahertz polymer waveguide emitters for telecom wavelengths using coupled mode theory.

    PubMed

    Vallejo, Felipe A; Hayden, L Michael

    2013-03-11

    We use coupled mode theory, adequately incorporating optical losses, to model ultra-broadband terahertz (THz) waveguide emitters (0.1-20 THz) based on difference frequency generation of femtosecond infrared (IR) optical pulses. We apply the model to a generic, symmetric, five-layer, metal/cladding/core waveguide structure using transfer matrix theory. We provide a design strategy for an efficient ultra-broadband THz emitter and apply it to polymer waveguides with a nonlinear core composed of a poled guest-host electro-optic polymer composite and pumped by a pulsed fiber laser system operating at 1567 nm. The predicted bandwidths are greater than 15 THz and we find a high conversion efficiency of 1.2 × 10(-4) W(-1) by balancing both the modal phase-matching and effective mode attenuation.

  19. The characterization of GH shifts of surface plasmon resonance in a waveguide using the FDTD method.

    PubMed

    Oh, Geum-Yoon; Kim, Doo Gun; Choi, Young-Wan

    2009-11-09

    We have explicated the Goos-Hänchen (GH) shift in a mum-order Kretchmann-Raether configuration embedded in an optical waveguide structure by using the finite-difference time-domain method. For optical waveguide-type surface plasmon resonance (SPR) devices, the precise derivation of the GH shift has become critical. Artmann's equation, which is accurate enough for bulk optics, is difficult to apply to waveguide-type SPR devices. This is because Artmann's equation, based on the differentiation of the phase shift, is inaccurate at the critical and resonance angles where drastic phase changes occur. In this study, we accurately identified both the positive and the negative GH shifts around the incidence angle of resonance. In a waveguide-type Kretchmann-Raether configuration with an Au thin film of 50 nm, positive and negative lateral shifts of -0.75 and + 1.0 microm are obtained on the SPR with the incident angles of 44.4 degrees and 47.5 degrees, respectively, at a wavelength of 632.8 nm.

  20. Heuristic modelling of laser written mid-infrared LiNbO3 stressed-cladding waveguides.

    PubMed

    Nguyen, Huu-Dat; Ródenas, Airán; Vázquez de Aldana, Javier R; Martínez, Javier; Chen, Feng; Aguiló, Magdalena; Pujol, Maria Cinta; Díaz, Francesc

    2016-04-04

    Mid-infrared lithium niobate cladding waveguides have great potential in low-loss on-chip non-linear optical instruments such as mid-infrared spectrometers and frequency converters, but their three-dimensional femtosecond-laser fabrication is currently not well understood due to the complex interplay between achievable depressed index values and the stress-optic refractive index changes arising as a function of both laser fabrication parameters, and cladding arrangement. Moreover, both the stress-field anisotropy and the asymmetric shape of low-index tracks yield highly birefringent waveguides not useful for most applications where controlling and manipulating the polarization state of a light beam is crucial. To achieve true high performance devices a fundamental understanding on how these waveguides behave and how they can be ultimately optimized is required. In this work we employ a heuristic modelling approach based on the use of standard optical characterization data along with standard computational numerical methods to obtain a satisfactory approximate solution to the problem of designing realistic laser-written circuit building-blocks, such as straight waveguides, bends and evanescent splitters. We infer basic waveguide design parameters such as the complex index of refraction of laser-written tracks at 3.68 µm mid-infrared wavelengths, as well as the cross-sectional stress-optic index maps, obtaining an overall waveguide simulation that closely matches the measured mid-infrared waveguide properties in terms of anisotropy, mode field distributions and propagation losses. We then explore experimentally feasible waveguide designs in the search of a single-mode low-loss behaviour for both ordinary and extraordinary polarizations. We evaluate the overall losses of s-bend components unveiling the expected radiation bend losses of this type of waveguides, and finally showcase a prototype design of a low-loss evanescent splitter. Developing a realistic waveguide model with which robust waveguide designs can be developed will be key for exploiting the potential of the technology.

  1. Novel image processing method study for a label-free optical biosensor

    NASA Astrophysics Data System (ADS)

    Yang, Chenhao; Wei, Li'an; Yang, Rusong; Feng, Ying

    2015-10-01

    Optical biosensor is generally divided into labeled type and label-free type, the former mainly contains fluorescence labeled method and radioactive-labeled method, while fluorescence-labeled method is more mature in the application. The mainly image processing methods of fluorescent-labeled biosensor includes smooth filtering, artificial gridding and constant thresholding. Since some fluorescent molecules may influence the biological reaction, label-free methods have been the main developing direction of optical biosensors nowadays. The using of wider field of view and larger angle of incidence light path which could effectively improve the sensitivity of the label-free biosensor also brought more difficulties in image processing, comparing with the fluorescent-labeled biosensor. Otsu's method is widely applied in machine vision, etc, which choose the threshold to minimize the intraclass variance of the thresholded black and white pixels. It's capacity-constrained with the asymmetrical distribution of images as a global threshold segmentation. In order to solve the irregularity of light intensity on the transducer, we improved the algorithm. In this paper, we present a new image processing algorithm based on a reflectance modulation biosensor platform, which mainly comprises the design of sliding normalization algorithm for image rectification and utilizing the improved otsu's method for image segmentation, in order to implement automatic recognition of target areas. Finally we used adaptive gridding method extracting the target parameters for analysis. Those methods could improve the efficiency of image processing, reduce human intervention, enhance the reliability of experiments and laid the foundation for the realization of high throughput of label-free optical biosensors.

  2. The use of optical waveguides in head up display (HUD) applications

    NASA Astrophysics Data System (ADS)

    Homan, Malcolm

    2013-06-01

    The application of optical waveguides to Head Up Displays (HUD) is an enabling technology which solves the critical issues of volume reduction (including cockpit intrusion) and mass reduction in an affordable product which retains the high performance optical capabilities associated with today's generation of digital display based HUDs. Improved operability and pilot comfort is achieved regardless of the installation by virtue of the intrinsic properties of optical waveguides and this has enabled BAE Systems Electronic Systems to develop two distinct product streams for glareshield and overhead HUD installations respectively. This paper addresses the design drivers behind the development of the next generation of Head Up Displays and their compatibility with evolving cockpit architectures and structures. The implementation of large scale optical waveguide combiners capable of matching and exceeding the display performances normally only associated with current digital display sourced HUDs has enabled BAE Systems Electronic Systems to solve the volume and installation challenges of the latest military and civil cockpits with it's LiteHUD® technology. Glareshield mounted waveguide based HUDs are compatible with the trend towards the addition of Large Area Displays (LAD) in place of the traditional multiple Head Down Displays (HDD) within military fast jet cockpits. They use an "indirect view" variant of the display which allows the amalgamation of high resolution digital display devices with the inherently small volume and low mass of the waveguide optics. This is then viewed using the more traditional technology of a conventional HUD combiner. This successful combination of technologies has resulted in the LPHUD product which is specifically designed by BAE Systems Electronic Systems to provide an ultra-low profile HUD which can be installed behind a LAD; still providing the level of performance that is at least equivalent to that of a conventional large volume glareshield mounted HUD. In many current Business Jet and Air Transport cockpits overhead mounted HUDs employ a conventional optical combiner to relay the display from a separate projector to the pilot's eyes. In BAE Systems' Electronic Systems QHUDTM configuration this combiner is replaced by the waveguide and the bulky, intrusive overhead projector completely eliminated. The result is a significant reduction in equipment volume and mass and a much greater head clearance combined with a substantially larger Head Motion Box. This latter feature is a fundamental outturn of waveguide optical solutions which removes the restrictions on pilot eye positioning associated with current conventional systems. LiteHUD®, developed by BAE Systems, Electronic Systems achieves equivalent optical performance to in-service HUDs for less cost, mass and volume.

  3. Terahertz bandwidth all-optical Hilbert transformers based on long-period gratings.

    PubMed

    Ashrafi, Reza; Azaña, José

    2012-07-01

    A novel, all-optical design for implementing terahertz (THz) bandwidth real-time Hilbert transformers is proposed and numerically demonstrated. An all-optical Hilbert transformer can be implemented using a uniform-period long-period grating (LPG) with a properly designed amplitude-only grating apodization profile, incorporating a single π-phase shift in the middle of the grating length. The designed LPG-based Hilbert transformers can be practically implemented using either fiber-optic or integrated-waveguide technologies. As a generalization, photonic fractional Hilbert transformers are also designed based on the same optical platform. In this general case, the resulting LPGs have multiple π-phase shifts along the grating length. Our numerical simulations confirm that all-optical Hilbert transformers capable of processing arbitrary optical signals with bandwidths well in the THz range can be implemented using feasible fiber/waveguide LPG designs.

  4. An automated optofluidic biosensor platform combining interferometric sensors and injection moulded microfluidics.

    PubMed

    Szydzik, C; Gavela, A F; Herranz, S; Roccisano, J; Knoerzer, M; Thurgood, P; Khoshmanesh, K; Mitchell, A; Lechuga, L M

    2017-08-08

    A primary limitation preventing practical implementation of photonic biosensors within point-of-care platforms is their integration with fluidic automation subsystems. For most diagnostic applications, photonic biosensors require complex fluid handling protocols; this is especially prominent in the case of competitive immunoassays, commonly used for detection of low-concentration, low-molecular weight biomarkers. For this reason, complex automated microfluidic systems are needed to realise the full point-of-care potential of photonic biosensors. To fulfil this requirement, we propose an on-chip valve-based microfluidic automation module, capable of automating such complex fluid handling. This module is realised through application of a PDMS injection moulding fabrication technique, recently described in our previous work, which enables practical fabrication of normally closed pneumatically actuated elastomeric valves. In this work, these valves are configured to achieve multiplexed reagent addressing for an on-chip diaphragm pump, providing the sample and reagent processing capabilities required for automation of cyclic competitive immunoassays. Application of this technique simplifies fabrication and introduces the potential for mass production, bringing point-of-care integration of complex automated microfluidics into the realm of practicality. This module is integrated with a highly sensitive, label-free bimodal waveguide photonic biosensor, and is demonstrated in the context of a proof-of-concept biosensing assay, detecting the low-molecular weight antibiotic tetracycline.

  5. Investigation of semiconductor clad optical waveguides

    NASA Technical Reports Server (NTRS)

    Batchman, T. E.; Mcwright, G.

    1981-01-01

    The properties of semiconductor-clad optical waveguides based on glass substrates were investigated. Computer modeling studies on four-layer silicon-clad planar dielectric waveguides indicated that the attenuation and mode index should behave as exponentially damped sinusoids as the silicon thickness is decreased below one micrometer. This effect can be explained as a periodic coupling between the guided modes of the lossless structure and the lossy modes supported by the high refractive index silicon. The computer studies also show that both the attenuation and mode index of the propagating mode are significantly altered by conductivity charges in the silicon. Silicon claddings were RF sputtered onto AgNO3-NaNO3 ion exchanged waveguides and preliminary measurements of attenuation were made. An expression was developed which predicts the attenuation of the silicon clad waveguide from the attenuation and phase characteristics of a silicon waveguide. Several applications of these clad waveguides are suggested and methods for increasing the photo response of the RF sputtered silicon films are described.

  6. Gold nanoparticle-based low limit of detection Love wave biosensor for carcinoembryonic antigens.

    PubMed

    Li, Shuangming; Wan, Ying; Su, Yan; Fan, Chunhai; Bhethanabotla, Venkat R

    2017-09-15

    In this work, a Love wave biosensing platform is described for detecting cancer-related biomarker carcinoembryonic antigen (CEA). An ST 90°-X quartz Love wave device with a layer of SiO 2 waveguide was combined with gold nanoparticles (Au NPs) to amplify the mass loading effect of the acoustic wave sensor to achieve a limit of detection of 37pg/mL. The strategy involves modifying the Au NPs with anti-CEA antibody conjugates to form nanoprobes in a sandwich immunoassay. The unamplified detection limit of the Love wave biosensor is 9.4ng/mL. This 2-3 order of magnitude reduction in the limit of detection brings the SAW platform into the range useful for clinical diagnosis. Measurement electronics and microfluidics are easily constructed for acoustic wave biosensors, such as the Love wave device described here, allowing for robust platforms for point of care applications for cancer biomarkers in general. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Optical keyboard

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Veligdan, James T.; Feichtner, John D.; Phillips, Thomas E.

    2001-01-01

    An optical keyboard includes an optical panel having optical waveguides stacked together. First ends of the waveguides define an inlet face, and opposite ends thereof define a screen. A projector transmits a light beam outbound through the waveguides for display on the screen as a keyboard image. A light sensor is optically aligned with the inlet face for sensing an inbound light beam channeled through the waveguides from the screen upon covering one key of the keyboard image.

  8. Alpha-fetoprotein detection by using a localized surface plasmon coupled fluorescence fiber-optic biosensor

    NASA Astrophysics Data System (ADS)

    Chang, Ying-Feng; Chen, Ran-Chou; Li, Ying-Chang; Yu, Chih-Jen; Hsieh, Bao-Yu; Chou, Chien

    2007-11-01

    Alpha-fetoprotein (AFP) detection by using a localized surface plasmon coupled fluorescence (LSPCF) fiber-optic biosensor is setup and experimentally demonstrated. It is based on gold nanoparticle (GNP) and coupled with localized surface plasmon wave on the surface of GNP. In this experiment, the fluorophores are labeled on anti-AFP which are bound to protein A conjugated GNP. Thus, LSPCF is excited with high efficiency in the near field of localized surface plasmon wave. Therefore, not only the sensitivity of LSPCF biosensor is enhanced but also the specific selectivity of AFP is improved. Experimentally, the ability of real time measurement in the range of AFP concentration from 0.1ng/ml to 100ng/ml was detected. To compare with conventional methods such as enzyme-linked immunosorbent assay (ELISA) or radioimmunoassay (RIA), the LSPCF fiber-optic biosensor performs higher or comparable detection sensitivity, respectively.

  9. Micromanipulation and microfabrication for optical microrobotics

    NASA Astrophysics Data System (ADS)

    Palima, Darwin; Bañas, Andrew Rafael; Vizsnyiczai, Gaszton; Kelemen, Lóránd; Aabo, Thomas; Ormos, Pál.; Glückstad, Jesper

    2012-10-01

    Robotics can use optics feedback in vision-based control of intelligent robotic guidance systems. With light's miniscule momentum, shrinking robots down to the microscale regime creates opportunities for exploiting optical forces and torques in microrobotic actuation and control. Indeed, the literature on optical trapping and micromanipulation attests to the possibilities for optical microrobotics. This work presents an optical microrobotics perspective on the optical microfabrication and micromanipulation work that we performed. We designed different three-dimensional microstructures and fabricated them by two-photon polymerization. These microstructures were then handled using our biophotonics workstation (BWS) for proof-of-principle demonstrations of optical actuation, akin to 6DOF actuation of robotic micromanipulators. Furthermore, we also show an example of dynamic behavior of the trapped microstructure that can be achieved when using static traps in the BWS. This can be generalized, in the future, towards a structural shaping optimization strategy for optimally controlling microstructures to complement approaches based on lightshaping. We also show that light channeled to microfabricated, free-standing waveguides can be used not only to redirect light for targeted delivery of optical energy but can also for targeted delivery of optical force, which can serve to further extend the manipulation arms in optical robotics. Moreover, light deflection with waveguide also creates a recoil force on the waveguide, which can be exploited for controlling the optical force.

  10. Fabrication of raised and inverted SU8 polymer waveguides

    NASA Astrophysics Data System (ADS)

    Holland, Anthony S.; Mitchell, Arnan; Balkunje, Vishal S.; Austin, Mike W.; Raghunathan, Mukund K.

    2005-01-01

    Polymer films with high optical transmission have been investigated for making optical devices for several years. SU8 photoresist and optical adhesives have been investigated for use as thin films for optical devices, not what they were originally designed for. Optical adhesives are typically a one component thermoset polymer and are convenient to use for making thin film optical devices such as waveguides. They are prepared in minutes as thin films unlike SU8, which has to be carefully thermally cured over several hours for optimum results. However SU8 can be accurately patterned to form the geometry of structures required for single mode optical waveguides. SU8 in combination with the lower refractive index optical adhesive films such as UV15 from Master Bond are used to form single and multi mode waveguides. SU8 is photopatternable but we have also used dry etching of the SU8 layer or the other polymer layers e.g. UV15 to form the ribs, ridges or trenches required to guide single modes of light. Optical waveguides were also fabricated using only optical adhesives of different refractive indices. The resolution obtainable is poorer than with SU8 and hence multi mode waveguides are obtained. Loss measurements have been obtained for waveguides of different geometries and material combinations. The process for making polymer waveguides is demonstrated for making large multi mode waveguides and microfluidic channels by scaling the process up in size.

  11. Precision Laser Development for Gravitational Wave Space Mission

    NASA Technical Reports Server (NTRS)

    Numata, Kenji; Camp, Jordan

    2011-01-01

    Optical fiber and semiconductor laser technologies have evolved dramatically over the last decade due to the increased demands from optical communications. We are developing a laser (master oscillator) and optical amplifier based on those technologies for interferometric space missions, such as the gravitational-wave mission LISA, and GRACE follow-on, by fully utilizing the mature wave-guided optics technologies. In space, where a simple and reliable system is preferred, the wave-guided components are advantageous over bulk, crystal-based, free-space laser, such as NPRO (Non-planar Ring Oscillator) and bulk-crystal amplifier, which are widely used for sensitive laser applications on the ground.

  12. Nonlinear silicon photonics

    NASA Astrophysics Data System (ADS)

    Borghi, M.; Castellan, C.; Signorini, S.; Trenti, A.; Pavesi, L.

    2017-09-01

    Silicon photonics is a technology based on fabricating integrated optical circuits by using the same paradigms as the dominant electronics industry. After twenty years of fervid development, silicon photonics is entering the market with low cost, high performance and mass-manufacturable optical devices. Until now, most silicon photonic devices have been based on linear optical effects, despite the many phenomenologies associated with nonlinear optics in both bulk materials and integrated waveguides. Silicon and silicon-based materials have strong optical nonlinearities which are enhanced in integrated devices by the small cross-section of the high-index contrast silicon waveguides or photonic crystals. Here the photons are made to strongly interact with the medium where they propagate. This is the central argument of nonlinear silicon photonics. It is the aim of this review to describe the state-of-the-art in the field. Starting from the basic nonlinearities in a silicon waveguide or in optical resonator geometries, many phenomena and applications are described—including frequency generation, frequency conversion, frequency-comb generation, supercontinuum generation, soliton formation, temporal imaging and time lensing, Raman lasing, and comb spectroscopy. Emerging quantum photonics applications, such as entangled photon sources, heralded single-photon sources and integrated quantum photonic circuits are also addressed at the end of this review.

  13. Kinetics of antigen binding to arrays of antibodies in different sized spots

    NASA Technical Reports Server (NTRS)

    Sapsford, K. E.; Liron, Z.; Shubin, Y. S.; Ligler, F. S.

    2001-01-01

    A fluorescence-based array biosensor has been developed which can measure the binding kinetics of an antigen to an immobilized antibody in real time. A patterned array of antibodies immobilized on the surface of a planar waveguide was used to capture a Cy5-labeled antigen present in a solution that was continuously flowed over the surface. The CCD image of the waveguide was monitored continuously for 25 min. The resulting exponential rise in fluorescence signal was determined by image analysis software and fitted to a reaction-limited kinetics model, giving a kf of 3.6 x 10(5) M(-1) s(-1). Different spot sizes were then patterned on the surface of the waveguide using either a PDMS flow cell or laser exposure, producing width sizes ranging from 80 to 1145 microm. It was demonstrated that under flow conditions, the reduction of spot size did not alter the association rate of the antigen with immobilized antibody; however, as the spot width decreased to < 200 nm, the signal intensity also decreased.

  14. Performance of optical biosensor using alcohol oxidase enzyme for formaldehyde detection

    NASA Astrophysics Data System (ADS)

    Sari, A. P.; Rachim, A.; Nurlely, Fauzia, V.

    2017-07-01

    The recent issue in the world is the long exposure of formaldehyde which is can increase the risk of human health, therefore, that is very important to develop a device and method that can be optimized to detect the formaldehyde elements accurately, have a long lifetime and can be fabricated and produced in large quantities. A new and simple prepared optical biosensor for detection of formaldehyde in aqueous solutions using alcohol oxidase (AOX) enzyme was successfully fabricated. The poly-n-butyl acrylic-co-N-acryloxysuccinimide (nBA-NAS) membranes containing chromoionophore ETH5294 were used for immobilization of alcohol oxidase enzyme (AOX). Biosensor response was based on the colour change of chromoionophore as a result of enzymatic oxidation of formaldehyde and correlated with the detection concentration of formaldehyde. The performance of biosensor parameters were measured through the optical absorption value using UV-Vis spectrophotometer including the repeatability, reproducibility, selectivity and lifetime. The results showed that the prepared biosensor has good repeatability (RSD = 1.9 %) and good reproducibility (RSD = 2.1 %). The biosensor was selective formaldehyde with no disturbance by methanol, ethanol, and acetaldehyde, and also stable before 49 days and decrease by 41.77 % after 49 days.

  15. Characteristics of silicon-based Sagnac optical switches using magneto-optical micro-ring array

    NASA Astrophysics Data System (ADS)

    Ni, Shuang; Wu, Baojian; Liu, Yawen

    2018-01-01

    The miniaturization and integration of optical switches are necessary for photonic switching networks and the utilization of magneto optical effects is a promising candidate. We propose a Sagnac optical switch chip based on the principle of nonreciprocal phase shift (NPS) of the magneto-optical (MO) micro-ring (MOMR) array, composed of SiO2/Si/Ce:YIG/SGGG. The MO switching function is realized by controlling the drive current in the snake-like metal microstrip circuit layered on the MOMRs. The transmission characteristics of the Sagnac MO switch chip dependent on magnetization intensity, waveguide coupling coefficient and waveguide loss are simulated. By optimizing the coupling coefficients, we design an MO switch using two serial MOMRs with a circumference of 38.37 μm, and the 3dB bandwidth and the extinction ratio are respectively up to 1.6 nm and 50dB for the waveguide loss coefficient of ?. And the switching magnetization can be further reduced by increasing the number of parallel MOMRs. The frequency response of the MO Sagnac switch is analyzed as well.

  16. Toward a biophotonic MEMS cell sensor

    NASA Astrophysics Data System (ADS)

    Powers, Michael A.; Koev, Stephan T.; Schleunitz, Arne; Yi, Hyunmin; Hodzic, Vildana; Bentley, William E.; Payne, Gregory F.; Rubloff, Gary W.; Ghodssi, Reza

    2005-06-01

    We present a new platform for the optical analysis of biomolecules based upon the polysaccharide chitosan. The versatile, stable, and compatible nature of chitosan makes it an ideal material for integrating biological materials in microfabricated systems. Chitosan"s pH-responsive solubility allows electrochemical deposition, while its chemical reactivity enables facile coupling of proteins, oligonucleotides, and other biomolecules by covalent bonds. This work demonstrates the spatially selective assembly of a fluorescent molecule on chitosan and its applicability to microscale optical transducers. We define multimode waveguides and fluidic channels on a Pyrex wafer using a single layer of SU-8. Our implementation of sidewall patterning of transparent electrodes (indium tin oxide) on SU-8 structures is demonstrated and can be highly beneficial to fluorescent signal transduction. In this optical configuration, normally incident excitation light illuminates a chitosan surface on the vertical face of a collector waveguide intersected by a microfluidic channel. We demonstrate the collection of the optical signal in the integrated waveguide and analyze the signal by coupling the waveguide to a grating spectrometer.

  17. Transverse single-mode edge-emitting lasers based on coupled waveguides.

    PubMed

    Gordeev, Nikita Yu; Payusov, Alexey S; Shernyakov, Yuri M; Mintairov, Sergey A; Kalyuzhnyy, Nikolay A; Kulagina, Marina M; Maximov, Mikhail V

    2015-05-01

    We report on the transverse single-mode emission from InGaAs/GaAs quantum well edge-emitting lasers with broadened waveguide. The lasers are based on coupled large optical cavity (CLOC) structures where high-order vertical modes of the broad active waveguide are suppressed due to their resonant tunneling into a coupled single-mode passive waveguide. The CLOC lasers have shown stable Gaussian-shaped vertical far-field profiles with a reduced divergence of ∼22° FWHM (full width at half-maximum) in CW (continuous-wave) operation.

  18. Optically-controlled extinction ratio and Q-factor tunable silicon microring resonators based on optical forces

    NASA Astrophysics Data System (ADS)

    Long, Yun; Wang, Jian

    2014-06-01

    Tunability is a desirable property of microring resonators to facilitate superior performance. Using light to control light, we present an alternative simple approach to tuning the extinction ratio (ER) and Q-factor of silicon microring resonators based on optical forces. We design an opto-mechanical tunable silicon microring resonator consisting of an add-drop microring resonator and a control-light-carrying waveguide (``controlling'' waveguide). One of the two bus waveguides of the microring resonator is a deformable nanostring put in parallel with the ``controlling'' waveguide. The tuning mechanism relies on the optical force induced deflection of suspended nanostring, leading to the change of coupling coefficient of microring and resultant tuning of ER and Q-factor. Two possible geometries, i.e. double-clamped nanostring and cantilever nanostring, are studied in detail for comparison. The obtained results imply a favorable structure with the microring positioned at the end of the cantilever nanostring. It features a wide tuning range of ER from 5.6 to 39.9 dB and Q-factor from 309 to 639 as changing the control power from 0 to 1.4 mW.

  19. Compact optical switch based on 2D photonic crystal and magneto-optical cavity.

    PubMed

    Dmitriev, Victor; Kawakatsu, Marcelo N; Portela, Gianni

    2013-04-01

    A compact optical switch based on a 2D photonic crystal (PhC) and a magneto-optical cavity is suggested and analyzed. The cavity is coupled to two parallel and misaligned PC waveguides and operates with dipole mode. When the cavity is nonmagnetized, the dipole mode excited by a signal in the input waveguide has a node in the output waveguide. Therefore, the input signal is reflected from the cavity. This corresponds to the state off of the switch. Normal to the plane of the PhC magnetization by a dc magnetic field produces a rotation of the dipole pattern in the cavity providing equal amplitudes of the electromagnetic fields in the input and the output waveguides. This corresponds to the state on with high transmission of the input signal. Numerical calculations show that at the 1.55 μm wavelength the device has the insertion loss -0.42 dB in the on state, the isolation -19 dB in the off state and the switch off and on ratio P(on)/P(off) about 72. The frequency band at the level of -15 dB of the resonance curve in off state is about 160 GHz.

  20. Nanophotonic Optical Isolator Controlled by the Internal State of Cold Atoms

    NASA Astrophysics Data System (ADS)

    Sayrin, Clément; Junge, Christian; Mitsch, Rudolf; Albrecht, Bernhard; O'Shea, Danny; Schneeweiss, Philipp; Volz, Jürgen; Rauschenbeutel, Arno

    2015-10-01

    The realization of nanophotonic optical isolators with high optical isolation even at ultralow light levels and low optical losses is an open problem. Here, we employ the link between the local polarization of strongly confined light and its direction of propagation to realize low-loss nonreciprocal transmission through a silica nanofiber at the single-photon level. The direction of the resulting optical isolator is controlled by the spin state of cold atoms. We perform our experiment in two qualitatively different regimes, i.e., with an ensemble of cold atoms where each atom is weakly coupled to the waveguide and with a single atom strongly coupled to the waveguide mode. In both cases, we observe simultaneously high isolation and high forward transmission. The isolator concept constitutes a nanoscale quantum optical analog of microwave ferrite resonance isolators, can be implemented with all kinds of optical waveguides and emitters, and might enable novel integrated optical devices for fiber-based classical and quantum networks.

  1. Low temperature and UV curable sol-gel coatings for long lasting optical fiber biosensors

    NASA Astrophysics Data System (ADS)

    Otaduy, D.; Villar, A.; Gomez-Herrero, E.; Goitandia, A. M.; Gorritxategi, E.; Quintana, I.

    2010-04-01

    The use of optical fibers as sensing element is increasing in clinical, pharmaceutical and industrial applications. Excellent light delivery, long interaction length, low cost and ability not only to excite the target molecules but also to capture the emitted light from the targets are the hallmarks of optical fiber as biosensors. In biosensors based on fiber optics the interaction with the analyte can occur within an element of the optical fiber. One of the techniques for this kind of biosensors is to remove the fiber optic cladding and substitute it for biological coatings that will interact with the parameter to sensorize. The deposition of these layers can be made by sol-gel technology. The sol-gel technology is being increasingly used mainly due to the high versatility to tailor their optical features. Incorporation of suitable chemical and biochemical sensing agents have allowed determining pH, gases, and biochemical species, among others. Nonetheless, the relatively high processing temperatures and short lifetime values mean severe drawbacks for a successful exploitation of sol-gel based coated optical fibres. With regard to the latter, herein we present the design, preparation and characterization of novel sol-gel coated optical fibres. Low temperature and UV curable coating formulations were optimized to achieve a good adhesion and optical performance. The UV photopolymerizable formulation was comprised by glycidoxypropyltrimethoxysilane (GLYMO), Tetraethylorthosilicate (TEOS) and an initiator. While the thermoset coating was prepared by using 3-aminopropyltrimethoxysilane, GLYMO, and TEOS as main reagents. Both curable sol-gel coated fibres were analysed by FTIR, SEM and optical characterization. Furthermore, in the present work a new technique for silica cladding removal has been developed by ultra-short pulses laser processing, getting good dimensional accuracy and surface integrity.

  2. Recent advances in nanomaterial-based biosensors for antibiotics detection.

    PubMed

    Lan, Lingyi; Yao, Yao; Ping, Jianfeng; Ying, Yibin

    2017-05-15

    Antibiotics are able to be accumulated in human body by food chain and may induce severe influence to human health and safety. Hence, the development of sensitive and simple methods for rapid evaluation of antibiotic levels is highly desirable. Nanomaterials with excellent electronic, optical, mechanical, and thermal properties have been recognized as one of the most promising materials for opening new gates in the development of next-generation biosensors. This review highlights the current advances in the nanomaterial-based biosensors for antibiotics detection. Different kinds of nanomaterials including carbon nanomaterials, metal nanomaterials, magnetic nanoparticles, up-conversion nanoparticles, and quantum dots have been applied to the construction of biosensors with two main signal-transducing mechanisms, i.e. optical and electrochemical. Furthermore, the current challenges and future prospects in this field are also included to provide an overview for future research directions. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Design, fabrication and analysis of integrated optical waveguide devices

    NASA Astrophysics Data System (ADS)

    Sikorski, Yuri

    Throughout the present dissertation, the main effort has been to develop the set of design rules for optical integrated circuits (OIC). At the present time, when planar optical integrated circuits seem to be the leading technology, and industry is heading towards much higher levels of integration, such design rules become necessary. It is known that analysis of light propagation in rectangular waveguides can not be carried out exactly. Various approximations become necessary, and their validity is discussed in this text. Various methods are used in the text for calculating the same problems, and results are compared. A few new concepts have been suggested to avoid approximations used elsewhere. The second part of this dissertation is directed to the development of a new technique for the fabrication of optical integrated circuits inside optical glass. This technique is based on the use of ultrafast laser pulses to alter the properties of glasses. Using this method we demonstrated the possibility of changing the refractive index of various passive and active optical glasses as well as ablating the material on the surface in a controlled fashion. A number of optical waveguide devices (e.g. waveguides, directional couplers, diffraction gratings, fiber Bragg gratings, V-grooves in dual-clad optical fibers, optical waveguide amplifiers) were fabricated and tested. Testing included measurements of loss/throughput, near-field mode profiles, efficiency and thermal stability. All of the experimental setup and test results are reported in the dissertation. We also demonstrated the possibility of using this technique to fabricate future bio-optical devices that will incorporate an OIC and a microfluidic circuit on a single substrate. Our results are expected to serve as a guide for the design and fabrication of a new generation of integrated optical and bio-optical devices.

  4. Recent Development in Optical Fiber Biosensors

    PubMed Central

    Bosch, María Espinosa; Sánchez, Antonio Jesús Ruiz; Rojas, Fuensanta Sánchez; Ojeda, Catalina Bosch

    2007-01-01

    Remarkable developments can be seen in the field of optical fibre biosensors in the last decade. More sensors for specific analytes have been reported, novel sensing chemistries or transduction principles have been introduced, and applications in various analytical fields have been realised. This review consists of papers mainly reported in the last decade and presents about applications of optical fiber biosensors. Discussions on the trends in optical fiber biosensor applications in real samples are enumerated.

  5. Background-free balanced optical cross correlator

    DOEpatents

    Nejadmalayeri, Amir Hossein; Kaertner, Franz X

    2014-12-23

    A balanced optical cross correlator includes an optical waveguide, a first photodiode including a first n-type semiconductor and a first p-type semiconductor positioned about the optical waveguide on a first side of the optical waveguide's point of symmetry, and a second photodiode including a second n-type semiconductor and a second p-type semiconductor positioned about the optical waveguide on a second side of the optical waveguide's point of symmetry. A balanced receiver including first and second inputs is configured to produce an output current or voltage that reflects a difference in currents or voltages, originating from the first and the second photodiodes of the balanced cross correlator and fed to the first input and to the second input of the balanced receiver.

  6. Propagation of eigenmodes and transfer functions in waveguide WDM structures

    NASA Astrophysics Data System (ADS)

    Mashkov, Vladimir A.; Francoeur, S.; Geuss, U.; Neiser, K.; Temkin, Henryk

    1998-02-01

    A method of propagation functions and transfer amplitudes suitable for the design of integrated optical circuits is presented. The method is based on vectorial formulation of electrodynamics: the distributions and propagation of electromagnetic fields in optical circuits is described by equivalent surface sources. This approach permits a division of complex optical waveguide structures into sets of primitive blocks and to separately calculate the transfer function and the transfer amplitude for each block. The transfer amplitude of the entire optical system is represented by a convolution of transfer amplitudes of its primitive blocks. The eigenvalues and eigenfunctions of arbitrary waveguide structure are obtained in the WKB approximation and compared with other methods. The general approach is illustrated with the transfer amplitude calculations for Dragone's star coupler and router.

  7. Frequency non-degenerate phase-sensitive optical parametric amplification based on four-wave-mixing in width-modulated silicon waveguides.

    PubMed

    Wang, Zhaolu; Liu, Hongjun; Sun, Qibing; Huang, Nan; Li, Xuefeng

    2014-12-15

    A width-modulated silicon waveguide is proposed to realize non-degenerate phase sensitive optical parametric amplification. It is found that the relative phase at the input of the phase sensitive amplifier (PSA) θIn-PSA can be tuned by tailoring the width and length of the second segment of the width-modulated silicon waveguide, which will influence the gain in the parametric amplification process. The maximum gain of PSA is larger by 9 dB compared with the phase insensitive amplifier (PIA) gain, and the gain bandwidth of PSA is larger by 35 nm compared with the gain bandwidth of PIA. Our on-chip PSA can find important potential applications in highly integrated optical circuits for optical chip-to-chip communication and computers.

  8. Frontiers in Chemical Sensors: Novel Principles and Techniques

    NASA Astrophysics Data System (ADS)

    Orellana, Guillermo; Moreno-Bondi, Maria Cruz

    This third volume of Springer Series on Chemical Sensors and Biosensors aims to enable the researcher or technologist to become acquainted with the latest principles and techniques that keep on enlarging the applications in this fascinating field. It deals with the novel luminescence lifetime-based techniques for interrogation of sensor arrays in high-throughput screening, cataluminescence, chemical sensing with hollow waveguides, new ways in sensor design and fabrication by means of either combinatorial methods or engineered indicator/support couples.

  9. Integrated-optical directional coupler biosensor

    NASA Astrophysics Data System (ADS)

    Luff, B. J.; Harris, R. D.; Wilkinson, J. S.; Wilson, R.; Schiffrin, D. J.

    1996-04-01

    We present measurements of biomolecular binding reactions, using a new type of integrated-optical biosensor based on a planar directional coupler structure. The device is fabricated by Ag+ - Na+ ion exchange in glass, and definition of the sensing region is achieved by use of transparent fluoropolymer isolation layers formed by thermal evaporation. The suitability of the sensor for application to the detection of environmental pollutants is considered.

  10. Design and analysis of optical waveguide elements in planar geometry

    NASA Astrophysics Data System (ADS)

    Mirkov, Mirko Georgiev

    1998-10-01

    This dissertation presents the theoretical analysis and practical design considerations for planar optical waveguide devices. The analysis takes into account both transverse dimensions of the waveguides and is based on the supermode theory combined with the resonance method for determination of the propagation constants and field profiles of the supermodes. An improved accuracy has been achieved by including the corrections due to the fields in the corner regions of the waveguides using perturbation theory. The following two classes of devices have been analyzed in detail. Curved rectangular waveguides are a common element in an integrated optics circuit. The theoretical analysis in this work shows that some commonly used approximations for determination of the propagation constants of the quasi-modes of the bent waveguides are not necessary. Specifically the imaginary part of the mode propagation constant, which determines the power loss, is calculated exactly using the resonance method, combined with a two- dimensional optimization routine for determination of the real and the imaginary parts of the propagation constants. Subsequently, the results are corrected for the effects of the fields in the corner regions. The latter corrections have not been previously computed and are shown to be significant. Power splitters are another common element of an integrated optical circuit. A new 'bend-free' splitter is suggested and analyzed. The new splitter design consists of only straight parallel channels, which considerably simplify both the analysis and the fabrication of the device. It is shown that a single design parameter determines the power splitting ratio, which can take any given value. The intrinsic power loss in the proposed splitter is minimal, which makes it an attractive alternative to the conventional Y-splitters. The accurate methods of analysis of planar optical waveguides developed in the present work can easily be applied to other integrated optic devices consisting of rectangular waveguides.

  11. A Photonic 1 × 4 Power Splitter Based on Multimode Interference in Silicon-Gallium-Nitride Slot Waveguide Structures.

    PubMed

    Malka, Dror; Danan, Yossef; Ramon, Yehonatan; Zalevsky, Zeev

    2016-06-25

    In this paper, a design for a 1 × 4 optical power splitter based on the multimode interference (MMI) coupler in a silicon (Si)-gallium nitride (GaN) slot waveguide structure is presented-to our knowledge, for the first time. Si and GaN were found as suitable materials for the slot waveguide structure. Numerical optimizations were carried out on the device parameters using the full vectorial-beam propagation method (FV-BPM). Simulation results show that the proposed device can be useful to divide optical signal energy uniformly in the C-band range (1530-1565 nm) into four output ports with low insertion losses (0.07 dB).

  12. Fundamentals of Enzyme-Based Sensors

    NASA Astrophysics Data System (ADS)

    Moreno-Bondi, María C.; Benito-Peña, Elena

    One of the mayor outbreaks in the development of analytical measurement techniques was the introduction, in the mid-twentieth century, of bioprobes for the analysis of chemical and biochemical compounds in real samples. The first devices, developed in the 1950's and 1960's by Clark et al. were based on electrochemical measurements and allowed the determination of oxygen and glucose in tissues and blood samples. Later on, in the 1970's, optical transduction was coupled to enzymatically-catalyzed reactions3 and since those early days the field of application of optical biosensors has broaden up considerably. According to the definition proposed by the International Union of Pure and Applied Chemistry (IUPAC): "A biosensor is a self-contained integrated device which is capable of providing specific quantitative or semi-quantitative analytical information using a biological recognition element (biochemical receptor) which is in direct spatial contact with a transducer element. A biosensor should be clearly distinguished from a bioanalytical system, which requires additional processing steps, such as reagent addition. Furthermore, a biosensor should be distinguished from a bioprobe which is either disposable after one measurement, i.e. single use, or unable to continuously monitor the analyte concentration". The general scheme of a biosensor configuration is shown in Figure 1. Biosensors that include transducers based on integrated circuit microchips are known as biochips.

  13. Surface enhanced Raman gene probe and methods thereof

    DOEpatents

    Vo-Dinh, T.

    1998-09-29

    The subject invention disclosed herein is a new gene probe biosensor and methods based on surface enhanced Raman scattering (SERS) label detection. The SER gene probe biosensor comprises a support means, a SER gene probe having at least one oligonucleotide strand labeled with at least one SERS label, and a SERS active substrate disposed on the support means and having at least one of the SER gene probes adsorbed thereon. Biotargets such as bacterial and viral DNA, RNA and PNA are detected using a SER gene probe via hybridization to oligonucleotide strands complementary to the SER gene probe. The support means supporting the SERS active substrate includes a fiberoptic probe, an array of fiberoptic probes for performance of multiple assays and a waveguide microsensor array with charge-coupled devices or photodiode arrays. 18 figs.

  14. Surface enhanced Raman gene probe and methods thereof

    DOEpatents

    Vo-Dinh, Tuan

    1998-01-01

    The subject invention disclosed herein is a new gene probe biosensor and methods thereof based on surface enhanced Raman scattering (SERS) label detection. The SER gene probe biosensor comprises a support means, a SER gene probe having at least one oligonucleotide strand labeled with at least one SERS label, and a SERS active substrate disposed on the support means and having at least one of the SER gene probes adsorbed thereon. Biotargets such as bacterial and viral DNA, RNA and PNA are detected using a SER gene probe via hybridization to oligonucleotide strands complementary to the SER gene probe. The support means supporting the SERS active substrate includes a fiberoptic probe, an array of fiberoptic probes for performance of multiple assays and a waveguide microsensor array with charge-coupled devices or photodiode arrays.

  15. Surface enhanced Raman gene probe and methods thereof

    DOEpatents

    Vo-Dinh, T.

    1998-02-24

    The subject invention disclosed is a new gene probe biosensor and methods based on surface enhanced Raman scattering (SERS) label detection. The SER gene probe biosensor comprises a support means, a SER gene probe having at least one oligonucleotide strand labeled with at least one SERS label, and a SERS active substrate disposed on the support means and having at least one of the SER gene probes adsorbed thereon. Biotargets such as bacterial and viral DNA, RNA and PNA are detected using a SER gene probe via hybridization to oligonucleotide strands complementary to the SER gene probe. The support means includes a fiberoptic probe, an array of fiberoptic probes for performance of multiple assays and a waveguide microsensor array with charge-coupled devices or photodiode arrays. 18 figs.

  16. Surface enhanced Raman gene probe and methods thereof

    DOEpatents

    Vo-Dinh, T.

    1998-07-21

    The subject invention disclosed is a new gene probe biosensor and methods based on surface enhanced Raman scattering (SERS) label detection. The SER gene probe biosensor comprises a support means, a SER gene probe having at least one oligonucleotide strand labeled with at least one SERS label, and a SERS active substrate disposed on the support means and having at least one of the SER gene probes adsorbed. Biotargets such as bacterial and viral DNA, RNA and PNA are detected using a SER gene probe via hybridization to oligonucleotide strands complementary to the SER gene probe. The support means supporting the SERS active substrate includes a fiberoptic probe, an array of fiberoptic probes for performance of multiple assays and a waveguide microsensor array with charge-coupled devices or photodiode arrays. 18 figs.

  17. DNA nanotechnology-enabled biosensors.

    PubMed

    Chao, Jie; Zhu, Dan; Zhang, Yinan; Wang, Lianhui; Fan, Chunhai

    2016-02-15

    Biosensors employ biological molecules to recognize the target and utilize output elements which can translate the biorecognition event into electrical, optical or mass-sensitive signals to determine the quantities of the target. DNA-based biosensors, as a sub-field to biosensor, utilize DNA strands with short oligonucleotides as probes for target recognition. Although DNA-based biosensors have offered a promising alternative for fast, simple and cheap detection of target molecules, there still exist key challenges including poor stability and reproducibility that hinder their competition with the current gold standard for DNA assays. By exploiting the self-recognition properties of DNA molecules, researchers have dedicated to make versatile DNA nanostructures in a highly rigid, controllable and functionalized manner, which offers unprecedented opportunities for developing DNA-based biosensors. In this review, we will briefly introduce the recent advances on design and fabrication of static and dynamic DNA nanostructures, and summarize their applications for fabrication and functionalization of DNA-based biosensors. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. A Large Response Range Reflectometric Urea Biosensor Made from Silica-Gel Nanoparticles

    PubMed Central

    Alqasaimeh, Muawia; Heng, Lee Yook; Ahmad, Musa; Raj, A.S. Santhana; Ling, Tan Ling

    2014-01-01

    A new silica-gel nanospheres (SiO2NPs) composition was formulated, followed by biochemical surface functionalization to examine its potential in urea biosensor development. The SiO2NPs were basically synthesized based on sol–gel chemistry using a modified Stober method. The SiO2NPs surfaces were modified with amine (-NH2) functional groups for urease immobilization in the presence of glutaric acid (GA) cross-linker. The chromoionophore pH-sensitive dye ETH 5294 was physically adsorbed on the functionalized SiO2NPs as pH transducer. The immobilized urease determined urea concentration reflectometrically based on the colour change of the immobilized chromoionophore as a result of the enzymatic hydrolysis of urea. The pH changes on the biosensor due to the catalytic enzyme reaction of immobilized urease were found to correlate with the urea concentrations over a linear response range of 50–500 mM (R2 = 0.96) with a detection limit of 10 mM urea. The biosensor response time was 9 min with reproducibility of less than 10% relative standard deviation (RSD). This optical urea biosensor did not show interferences by Na+, K+, Mg2+ and NH4+ ions. The biosensor performance has been validated using urine samples in comparison with a non-enzymatic method based on the use of p-dimethylaminobenzaldehyde (DMAB) reagent and demonstrated a good correlation between the two different methods (R2 = 0.996 and regression slope of 1.0307). The SiO2NPs-based reflectometric urea biosensor showed improved dynamic linear response range when compared to other nanoparticle-based optical urea biosensors. PMID:25054632

  19. Modes in light wave propagating in semiconductor laser

    NASA Technical Reports Server (NTRS)

    Manko, Margarita A.

    1994-01-01

    The study of semiconductor laser based on an analogy of the Schrodinger equation and an equation describing light wave propagation in nonhomogeneous medium is developed. The active region of semiconductor laser is considered as optical waveguide confining the electromagnetic field in the cross-section (x,y) and allowing waveguide propagation along the laser resonator (z). The mode structure is investigated taking into account the transversal and what is the important part of the suggested consideration longitudinal nonhomogeneity of the optical waveguide. It is shown that the Gaussian modes in the case correspond to spatial squeezing and correlation. Spatially squeezed two-mode structure of nonhomogeneous optical waveguide is given explicitly. Distribution of light among the laser discrete modes is presented. Properties of the spatially squeezed two-mode field are described. The analog of Franck-Condon principle for finding the maxima of the distribution function and the analog of Ramsauer effect for control of spatial distribution of laser emission are discussed.

  20. Highly localized distributed Brillouin scattering response in a photonic integrated circuit

    NASA Astrophysics Data System (ADS)

    Zarifi, Atiyeh; Stiller, Birgit; Merklein, Moritz; Li, Neuton; Vu, Khu; Choi, Duk-Yong; Ma, Pan; Madden, Stephen J.; Eggleton, Benjamin J.

    2018-03-01

    The interaction of optical and acoustic waves via stimulated Brillouin scattering (SBS) has recently reached on-chip platforms, which has opened new fields of applications ranging from integrated microwave photonics and on-chip narrow-linewidth lasers, to phonon-based optical delay and signal processing schemes. Since SBS is an effect that scales exponentially with interaction length, on-chip implementation on a short length scale is challenging, requiring carefully designed waveguides with optimized opto-acoustic overlap. In this work, we use the principle of Brillouin optical correlation domain analysis to locally measure the SBS spectrum with high spatial resolution of 800 μm and perform a distributed measurement of the Brillouin spectrum along a spiral waveguide in a photonic integrated circuit. This approach gives access to local opto-acoustic properties of the waveguides, including the Brillouin frequency shift and linewidth, essential information for the further development of high quality photonic-phononic waveguides for SBS applications.

  1. Integrated narrowband optical filter based on embedded subwavelength resonant grating structures

    DOEpatents

    Grann, Eric B.; Sitter, Jr., David N.

    2000-01-01

    A resonant grating structure in a waveguide and methods of tuning the performance of the grating structure are described. An apparatus includes a waveguide; and a subwavelength resonant grating structure embedded in the waveguide. The systems and methods provide advantages including narrowband filtering capabilities, minimal sideband reflections, spatial control, high packing density, and tunability.

  2. Multistage Polymeric Lens Structures Integrated into Silica Waveguides

    NASA Astrophysics Data System (ADS)

    Tate, Atsushi; Suzuki, Takanori; Tsuda, Hiroyuki

    2006-08-01

    A waveguide lens, composed of multistage polymer-filled thin grooves in a silica planar lightwave circuit (PLC) is proposed and a low-loss structure has been designed. A waveguide lens in a silica slab waveguide has been fabricated using reactive ion etching (RIE) and formed by filling with polymer. Both an imagding optical system and a Fourier-transform optical system can be configured in a PLC using a waveguide lens. It renders the PLC functional and its design flexible. To obtain a shorter focal length with a low insertion loss, it is more effective to use a multistage lens structure. An imaging optical system and a Fourier-transform optical system with a focal length of less than 1000 μm were fabricated in silica waveguides using a multistage lens structure. The lens imaging waveguides incorporate a 16-24-stage lens, with insertion losses of 4-7 dB. A 4 × 4 optical coupler, using a Fourier-transform optical system, utilizes a 6-stage lens with losses of 2-4 dB.

  3. Recycling microcavity optical biosensors.

    PubMed

    Hunt, Heather K; Armani, Andrea M

    2011-04-01

    Optical biosensors have tremendous potential for commercial applications in medical diagnostics, environmental monitoring, and food safety evaluation. In these applications, sensor reuse is desirable to reduce costs. To achieve this, harsh, wet chemistry treatments are required to remove surface chemistry from the sensor, typically resulting in reduced sensor performance and increased noise due to recognition moiety and optical transducer degradation. In the present work, we suggest an alternative, dry-chemistry method, based on O2 plasma treatment. This approach is compatible with typical fabrication of substrate-based optical transducers. This treatment completely removes the recognition moiety, allowing the transducer surface to be refreshed with new recognition elements and thus enabling the sensor to be recycled.

  4. Femtosecond laser micromachining of waveguides in silicone-based hydrogel polymers.

    PubMed

    Ding, Li; Blackwell, Richard I; Künzler, Jay F; Knox, Wayne H

    2008-06-10

    By tightly focusing 27 fs laser pulses from a Ti:sapphire oscillator with 1.3 nJ pulse energy at 93 MHz repetition rate, we are able to fabricate optical waveguides inside hydrogel polymers containing approximately 36% water by weight. A tapered lensed fiber is used to couple laser light at a wavelength of 632.8 nm into these waveguides within a water environment. Strong waveguiding is observed due to large refractive index changes. A large waveguide propagation loss is found, and we show that this is caused by surface roughness which can be reduced by optimizing the waveguides.

  5. Recent advances in rapid pathogen detection method based on biosensors.

    PubMed

    Chen, Ying; Wang, Zhenzhen; Liu, Yingxun; Wang, Xin; Li, Ying; Ma, Ping; Gu, Bing; Li, Hongchun

    2018-06-01

    As strain variation and drug resistance become more pervasive, the prevention and control of infection have been a serious problem in recent years. The detection of pathogen is one of the most important parts of the process of diagnosis. Having a series of advantages, such as rapid response, high sensitivity, ease of use, and low cost, biosensors have received much attention and been studied deeply. Moreover, relying on its characteristics of small size, real time, and multiple analyses, biosensors have developed rapidly and used widely and are expected to be applied for microbiological detection in order to meet higher accuracy required by clinical diagnosis. The main goal of this contribution is not to simply collect and list all papers related to pathogen detection based on biosensors published recently, but to discuss critically the development and application of many kinds of biosensors such as electrochemical (amperometric, impedimetric, potentiometric, and conductometric), optical (fluorescent, fibre optic and surface plasmon resonance), and piezoelectric (quartz crystal microbalances and atomic force microscopy) biosensors in pathogen detection as well as the comparisons with the existing clinical detection methods (traditional culture, enzyme-linked immunosorbent assay, polymerase chain reaction, and mass spectrometry).

  6. REVIEW ARTICLE: Environmental applications of analytical biosensors

    NASA Astrophysics Data System (ADS)

    Marco, María-Pilar; Barceló, Damià

    1996-11-01

    A review of the fundamental aspects and environmental applications of biosensors is presented. The bases of different transducer principles such as electrochemical, optical and piezoelectric are discussed. Various examples are given of the applications of such principles to develop immunosensor devices to determine common environmental contaminants. Attention is also paid to catalytic biosensors, using enzymes as sensing elements. Biosensor devices based on the use of cholinesterase and various oxidase enzymes such as tyrosinase, laccase, peroxidase and aldehyde dehydrogenase are reported. Some examples are given of the applications of other biomolecules such as whole cells, DNA or proteins, to determine pollution. Validation studies are presented comparing biosensors with chromatographic techniques to determine organophosphorus pesticides and phenolic compounds in environmental samples.

  7. Electrochemical and optical biosensors based on nanomaterials and nanostructures: a review.

    PubMed

    Li, Ming; Li, Rui; Li, Chang Ming; Wu, Nianqiang

    2011-06-01

    Nanomaterials and nanostructures exhibit unique size-tunable and shape-dependent physicochemical properties that are different from those of bulk materials. Advances of nanomaterials and nanostructures open a new door to develop various novel biosensors. The present work has reviewed the recent progress in electrochemical, surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS) and fluorescent biosensors based on nanomaterials and nanostructures. An emphasis is put on the research that demonstrates how the performance of biosensors such as the limit of detection, sensitivity and selectivity is improved by the use of nanomaterials and nanostructures.

  8. FIBER AND INTEGRATED OPTICS: Optimization of optical film waveguides

    NASA Astrophysics Data System (ADS)

    Adamson, P. V.

    1990-10-01

    Theoretical investigations were made of the possibility of optimization of the effective thickness, of the optical confinement factor Γ1, and of the birefringence of a planar dielectric waveguide as a function of the waveguide parameter V and the waveguide asymmetry. For a given value of V it is possible to ensure higher values of Γ1, for an asymmetric waveguide than for a symmetric one. An approximate expression is proposed for the factor Γ1, of an asymmetric waveguide directly in terms of its thickness and the refractive indices of the layers.

  9. Portable guided-mode resonance biosensor platform for point-of-care testing

    NASA Astrophysics Data System (ADS)

    Sung, Gun Yong; Kim, Wan-Joong; Ko, Hyunsung; Kim, Bong K.; Kim, Kyung-Hyun; Huh, Chul; Hong, Jongcheol

    2012-10-01

    It represents a viable solution for the realization of a portable biosensor platform that could screen/diagnose acute myocardial infarction by measuring cardiac marker concentrations such as cardiac troponin I (cTnI), creatine kinase MB (CK-MB), and myoglobin (MYO) for application to u-health monitoring system. The portable biosensor platform introduced in this presentation has a more compact structure and a much higher measuring resolution than a conventional spectrometer system. Portable guided-mode resonance (GMR) biosensor platform was composed of a biosensor chip stage, an optical pick-up module, and a data display panel. Disposable plastic GMR biosensor chips with nano-grating patterns were fabricated by injection-molding. Whole blood filtration and label-free immunoassay were performed on these single chips, automatically. Optical pick-up module was fabricated by using the miniaturized bulk optics and the interconnecting optical fibers and a tunable VCSEL (vertical cavity surface emitting laser). The reflectance spectrum from the GMR biosensor was measured by the optical pick-up module. Cardiac markers in human serum with concentrations less than 0.1ng/mL were analyzed using a GMR biosensor. Analysis time was 30min, which is short enough to meet clinical requirements. Our results show that the GMR biosensor will be very useful in developing lowcost portable biosensors that can screen for cardiac diseases.

  10. Geometrical tuning art for entirely subwavelength grating waveguide based integrated photonics circuits

    DOE PAGES

    Wang, Zheng; Xu, Xiaochuan; Fan, Donglei; ...

    2016-05-05

    Here, subwavelength grating (SWG) waveguide is an intriguing alternative to conventional optical waveguides due to the extra degree of freedom it offers in tuning a few important waveguide properties, such as dispersion and refractive index. Devices based on SWG waveguides have demonstrated impressive performances compared to conventional waveguides. However, the high loss of SWG waveguide bends jeopardizes their applications in integrated photonic circuits. In this work, we propose a geometrical tuning art, which realizes a pre-distorted refractive index profile in SWG waveguide bends. The pre-distorted refractive index profile can effectively reduce the mode mismatch and radiation loss simultaneously, thus significantlymore » reduce the bend loss. This geometry tuning art has been numerically optimized and experimentally demonstrated in present study. Through such tuning, the average insertion loss of a 5 μm SWG waveguide bend is reduced drastically from 5.43 dB to 1.10 dB per 90° bend for quasi-TE polarization. In the future, the proposed scheme will be utilized to enhance performance of a wide range of SWG waveguide based photonics devices.« less

  11. Geometrical tuning art for entirely subwavelength grating waveguide based integrated photonics circuits

    PubMed Central

    Wang, Zheng; Xu, Xiaochuan; Fan, Donglei; Wang, Yaguo; Subbaraman, Harish; Chen, Ray T.

    2016-01-01

    Subwavelength grating (SWG) waveguide is an intriguing alternative to conventional optical waveguides due to the extra degree of freedom it offers in tuning a few important waveguide properties, such as dispersion and refractive index. Devices based on SWG waveguides have demonstrated impressive performances compared to conventional waveguides. However, the high loss of SWG waveguide bends jeopardizes their applications in integrated photonic circuits. In this work, we propose a geometrical tuning art, which realizes a pre-distorted refractive index profile in SWG waveguide bends. The pre-distorted refractive index profile can effectively reduce the mode mismatch and radiation loss simultaneously, thus significantly reduce the bend loss. This geometry tuning art has been numerically optimized and experimentally demonstrated in present study. Through such tuning, the average insertion loss of a 5 μm SWG waveguide bend is reduced drastically from 5.43 dB to 1.10 dB per 90° bend for quasi-TE polarization. In the future, the proposed scheme will be utilized to enhance performance of a wide range of SWG waveguide based photonics devices. PMID:27145872

  12. Geometrical tuning art for entirely subwavelength grating waveguide based integrated photonics circuits.

    PubMed

    Wang, Zheng; Xu, Xiaochuan; Fan, Donglei; Wang, Yaguo; Subbaraman, Harish; Chen, Ray T

    2016-05-05

    Subwavelength grating (SWG) waveguide is an intriguing alternative to conventional optical waveguides due to the extra degree of freedom it offers in tuning a few important waveguide properties, such as dispersion and refractive index. Devices based on SWG waveguides have demonstrated impressive performances compared to conventional waveguides. However, the high loss of SWG waveguide bends jeopardizes their applications in integrated photonic circuits. In this work, we propose a geometrical tuning art, which realizes a pre-distorted refractive index profile in SWG waveguide bends. The pre-distorted refractive index profile can effectively reduce the mode mismatch and radiation loss simultaneously, thus significantly reduce the bend loss. This geometry tuning art has been numerically optimized and experimentally demonstrated in present study. Through such tuning, the average insertion loss of a 5 μm SWG waveguide bend is reduced drastically from 5.43 dB to 1.10 dB per 90° bend for quasi-TE polarization. In the future, the proposed scheme will be utilized to enhance performance of a wide range of SWG waveguide based photonics devices.

  13. Subwavelength grating enabled on-chip ultra-compact optical true time delay line

    PubMed Central

    Wang, Junjia; Ashrafi, Reza; Adams, Rhys; Glesk, Ivan; Gasulla, Ivana; Capmany, José; Chen, Lawrence R.

    2016-01-01

    An optical true time delay line (OTTDL) is a basic photonic building block that enables many microwave photonic and optical processing operations. The conventional design for an integrated OTTDL that is based on spatial diversity uses a length-variable waveguide array to create the optical time delays, which can introduce complexities in the integrated circuit design. Here we report the first ever demonstration of an integrated index-variable OTTDL that exploits spatial diversity in an equal length waveguide array. The approach uses subwavelength grating waveguides in silicon-on-insulator (SOI), which enables the realization of OTTDLs having a simple geometry and that occupy a compact chip area. Moreover, compared to conventional wavelength-variable delay lines with a few THz operation bandwidth, our index-variable OTTDL has an extremely broad operation bandwidth practically exceeding several tens of THz, which supports operation for various input optical signals with broad ranges of central wavelength and bandwidth. PMID:27457024

  14. Subwavelength grating enabled on-chip ultra-compact optical true time delay line.

    PubMed

    Wang, Junjia; Ashrafi, Reza; Adams, Rhys; Glesk, Ivan; Gasulla, Ivana; Capmany, José; Chen, Lawrence R

    2016-07-26

    An optical true time delay line (OTTDL) is a basic photonic building block that enables many microwave photonic and optical processing operations. The conventional design for an integrated OTTDL that is based on spatial diversity uses a length-variable waveguide array to create the optical time delays, which can introduce complexities in the integrated circuit design. Here we report the first ever demonstration of an integrated index-variable OTTDL that exploits spatial diversity in an equal length waveguide array. The approach uses subwavelength grating waveguides in silicon-on-insulator (SOI), which enables the realization of OTTDLs having a simple geometry and that occupy a compact chip area. Moreover, compared to conventional wavelength-variable delay lines with a few THz operation bandwidth, our index-variable OTTDL has an extremely broad operation bandwidth practically exceeding several tens of THz, which supports operation for various input optical signals with broad ranges of central wavelength and bandwidth.

  15. Three-mode all-optical (de)multiplexing on a SOI chip

    NASA Astrophysics Data System (ADS)

    Le, Yan-Si; Wang, Zhi; Li, Zhi-Yong; Li, Ying; Li, Qiang; Cui, Can; Wu, Chong-Qing

    2018-01-01

    An on-chip three-mode division multiplexing circuit using a simple ADC-based TE0 & TE1 & TE2 (de)multiplexer is demonstrated to improve the link capacity of on-chip optical interconnects. The proposed (de)multiplexer does not contain any tapered waveguide which is different from the previous mode (de)multiplexer based on ADCs. Here, we choose multimode waveguide width first and then confirm corresponding width of the other two waveguides. Thus the bus waveguide without any tapers can not only reduce complexity of (de)multiplexer but also reduce difficulty of the fabrication. Our simulation results show that the hybrid multiplexer has relatively low loss and low crosstalk about -40 dB, -26.99 dB and -28.72 dB for each mode around 1550 nm with a width-variation w =± 25 nm. These properties make the proposed mode-(de)multiplexer suitable for application in high-capacity data transmission.

  16. FIBER OPTICS: Method of calculation of the propagation constant for guided modes

    NASA Astrophysics Data System (ADS)

    Ardasheva, L. I.; Sadykov, Nail R.; Chernyakov, V. E.

    1992-09-01

    A new method of calculating the propagation constants and wave eigenfunctions of guided modes is proposed for axisymmetric translationally invariant fiber-optic waveguides with arbitrary refractive index profiles. The method is based on solving a parabolic scalar wave equation. A comparison is made between the numerical solution under steady-state conditions and the eigenfunctions of single-mode and multimode waveguides.

  17. Ultrapure glass optical waveguide: Development in microgravity by the sol gel process

    NASA Technical Reports Server (NTRS)

    Mukherjee, S. P.; Debsikdar, J. C.; Beam, T.

    1983-01-01

    The sol-gel process for the preparation of homogeneous gels in three binary oxide systems was investigated. The glass forming ability of certain compositions in the selected oxide systems (SiO-GeO2, GeO2-PbO, and SiO2-TiO2) were studied based on their potential importance in the design of optical waveguide at longer wavelengths.

  18. Study of a computer-controlled integrated optical gas-concentration sensor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Egorov, A A; Egorov, M A; Chekhlova, T K

    2008-08-31

    A computer-controlled integrated optical waveguide sensor based on an optical waveguide of the diffusion type with the low attenuation coefficient is developed and studied. It is shown that the response time of the sensor is {approx}0.15 s. According to tests and computer simulations, the sensor can detect gaseous ammonia in air with the limiting theoretical concentration of {approx}0.1 ppm for the signal-to-noise ratio no less than 20. (laser applications and other topics in quantum electronics)

  19. Planar dielectric waveguides in rotation are optical fibers: comparison with the classical model.

    PubMed

    Peña García, Antonio; Pérez-Ocón, Francisco; Jiménez, José Ramón

    2008-01-21

    A novel and simpler method to calculate the main parameters in fiber optics is presented. This method is based in a planar dielectric waveguide in rotation and, as an example, it is applied to calculate the turning points and the inner caustic in an optical fiber with a parabolic refractive index. It is shown that the solution found using this method agrees with the standard (and more complex) method, whose solutions for these points are also summarized in this paper.

  20. Silicon photonic IC embedded optical-PCB for high-speed interconnect application

    NASA Astrophysics Data System (ADS)

    Kallega, Rakshitha; Nambiar, Siddharth; Kumar, Abhai; Ranganath, Praveen; Selvaraja, Shankar Kumar

    2018-02-01

    Optical-Printed Circuit Board (PCB) is an emerging optical interconnect technology to bridge the gap between the board edge and the processing module. The technology so far has been used as a broadband transmitter using polymer waveguides in the PCB. In this paper, we report a Silicon Nitride based photonic IC embedded in the PCB along with the polymers as waveguides in the PCB. The motivation for such integration is to bring routing capability and to reduce the power loss due to broadcasting mode.

  1. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Study of a computer-controlled integrated optical gas-concentration sensor

    NASA Astrophysics Data System (ADS)

    Egorov, A. A.; Egorov, M. A.; Chekhlova, T. K.; Timakin, A. G.

    2008-08-01

    A computer-controlled integrated optical waveguide sensor based on an optical waveguide of the diffusion type with the low attenuation coefficient is developed and studied. It is shown that the response time of the sensor is ≈0.15 s. According to tests and computer simulations, the sensor can detect gaseous ammonia in air with the limiting theoretical concentration of ≈0.1 ppm for the signal-to-noise ratio no less than 20.

  2. Using Complementary Acoustic and Optical Techniques for Quantitative Monitoring of Biomolecular Adsorption at Interfaces

    PubMed Central

    Konradi, Rupert; Textor, Marcus; Reimhult, Erik

    2012-01-01

    The great wealth of different surface sensitive techniques used in biosensing, most of which claim to measure adsorbed mass, can at first glance look unnecessary. However, with each technique relying on a different transducer principle there is something to be gained from a comparison. In this tutorial review, different optical and acoustic evanescent techniques are used to illustrate how an understanding of the transducer principle of each technique can be exploited for further interpretation of hydrated and extended polymer and biological films. Some of the most commonly used surface sensitive biosensor techniques (quartz crystal microbalance, optical waveguide spectroscopy and surface plasmon resonance) are briefly described and five case studies are presented to illustrate how different biosensing techniques can and often should be combined. The case studies deal with representative examples of adsorption of protein films, polymer brushes and lipid membranes, and describe e.g., how to deal with strongly vs. weakly hydrated films, large conformational changes and ordered layers of biomolecules. The presented systems and methods are compared to other representative examples from the increasing literature on the subject. PMID:25586027

  3. Polymer/silica hybrid waveguide temperature sensor based on asymmetric Mach-Zehnder interferometer

    NASA Astrophysics Data System (ADS)

    Niu, Donghai; Wang, Xibin; Sun, Shiqi; Jiang, Minghui; Xu, Qiang; Wang, Fei; Wu, Yuanda; Zhang, Daming

    2018-04-01

    A highly sensitive waveguide temperature sensor based on asymmetric Mach-Zehnder interferometer was designed and experimentally demonstrated. The interferometer is based on the polymer/silica hybrid waveguide structure, and Norland Optical Adhesive 73 (NOA 73) was employed as the waveguide core to enhance the temperature sensitivity. The influence of the different length differences between the two interferometer arms on the sensitivity of the sensor was systemically studied. It is shown that the maximum temperature sensitivity of -431 pm °C-1 can be obtained in the range of 25 °C-75 °C, while the length difference is 92 μm. Moreover, the temperature sensitivity contributions from different core materials were also investigated experimentally. It is shown that the waveguide material and microstructure of the device have significant influences on the sensitivity of the waveguide temperature sensor.

  4. Electro-optical line cards with multimode polymer waveguides for chip-to-chip interconnects

    NASA Astrophysics Data System (ADS)

    Zhu, Long Xiu; Immonen, Marika; Wu, Jinhua; Yan, Hui Juan; Shi, Ruizhi; Chen, Peifeng; Rapala-Virtanen, Tarja

    2014-10-01

    In this paper, we report developments of electro-optical PCBs (EO-PCB) with low-loss (<0.05dB/cm) polymer waveguides. Our results shows successful fabrication of complex waveguide structures part of hybrid EO-PCBs utilizing production scale process on standard board panels. Test patterns include 90° bends of varying radii (40mm - 2mm), waveguide crossing with varied crossing angles (90°-20°), cascaded bends with varying radii, splitters and tapered waveguides. Full ranges of geometric configurations are required to meet practical optical routing functions and layouts. Moreover, we report results obtained to realize structures to integrate optical connectors with waveguides. Experimental results are shown for MT in-plane and 90° out-of-plane optical connectors realized with coupling loss < 2dB and < 2.5 dB, respectively. These connectors are crucial to realize efficient light coupling from/to TX/RX chip-to-waveguide and within waveguide-to-fiber connections in practical optical PCBs. Furthermore, we show results for fabricating electrical interconnect structures e.g. tracing layers, vias, plated vias top/bottom and through optical layers. Process compatibility with accepted practices and production scale up for high volumes are key concerns to meet the yield target and cost efficiency. Results include waveguide characterization, transmission loss, misalignment tolerance, and effect of lamination. Critical link metrics are reported.

  5. Design and analysis of a silicon-based antiresonant reflecting optical waveguide chemical sensor

    NASA Astrophysics Data System (ADS)

    Remley, Kate A.; Weisshaar, Andreas

    1996-08-01

    The design of a silicon-based antiresonant reflecting optical waveguide (ARROW) chemical sensor is presented, and its theoretical performance is compared with that of a conventional structure. The use of an ARROW structure permits incorporation of a thick guiding region for efficient coupling to a single-mode fiber. A high-index overlay is added to fine tune the sensitivity of the ARROW chemical sensor. The sensitivity of the sensor is presented, and design trade-offs are discussed.

  6. Integrated Optical Dipole Trap for Cold Neutral Atoms with an Optical Waveguide Coupler

    NASA Astrophysics Data System (ADS)

    Lee, J.; Park, D. H.; Mittal, S.; Meng, Y.; Dagenais, M.; Rolston, S. L.

    2013-05-01

    Using an optical waveguide, an integrated optical dipole trap uses two-color (red and blue-detuned) traveling evanescent wave fields for trapping cold neutral atoms. To achieve longitudinal confinement, we propose using an integrated optical waveguide coupler, which provides a potential gradient along the beam propagation direction sufficient to confine atoms. This integrated optical dipole trap can support an atomic ensemble with a large optical depth due to its small mode area. Its quasi-TE0 waveguide mode has an advantage over the HE11 mode of a nanofiber, with little inhomogeneous Zeeman broadening at the trapping region. The longitudinal confinement eliminates the need for a 1D optical lattice, reducing collisional blockaded atomic loading, potentially producing larger ensembles. The waveguide trap allows for scalability and integrability with nano-fabrication technology. We analyze the potential performance of such integrated atom traps and present current research progress towards a fiber-coupled silicon nitride optical waveguide integrable with atom chips. Work is supported by the ARO Atomtronics MURI. Work is supported by the ARO Atomtronics MURI.

  7. Highly stable porous silicon-carbon composites as label-free optical biosensors.

    PubMed

    Tsang, Chun Kwan; Kelly, Timothy L; Sailor, Michael J; Li, Yang Yang

    2012-12-21

    A stable, label-free optical biosensor based on a porous silicon-carbon (pSi-C) composite is demonstrated. The material is prepared by electrochemical anodization of crystalline Si in an HF-containing electrolyte to generate a porous Si template, followed by infiltration of poly(furfuryl) alcohol (PFA) and subsequent carbonization to generate the pSi-C composite as an optically smooth thin film. The pSi-C sensor is significantly more stable toward aqueous buffer solutions (pH 7.4 or 12) compared to thermally oxidized (in air, 800 °C), hydrosilylated (with undecylenic acid), or hydrocarbonized (with acetylene, 700 °C) porous Si samples prepared and tested under similar conditions. Aqueous stability of the pSi-C sensor is comparable to related optical biosensors based on porous TiO(2) or porous Al(2)O(3). Label-free optical interferometric biosensing with the pSi-C composite is demonstrated by detection of rabbit IgG on a protein-A-modified chip and confirmed with control experiments using chicken IgG (which shows no affinity for protein A). The pSi-C sensor binds significantly more of the protein A capture probe than porous TiO(2) or porous Al(2)O(3), and the sensitivity of the protein-A-modified pSi-C sensor to rabbit IgG is found to be ~2× greater than label-free optical biosensors constructed from these other two materials.

  8. An acousto-optic sensor based on resonance grating waveguide structure

    PubMed Central

    Xie, Antonio Jou; Song, Fuchuan; Seo, Sang-Woo

    2014-01-01

    This paper presents an acousto-optic (AO) sensor based on resonance grating waveguide structure. The sensor is fabricated using elastic polymer materials to achieve a good sensitivity to ultrasound pressure waves. Ultrasound pressure waves modify the structural parameters of the sensor and result in the optical resonance shift of the sensor. This converts into a light intensity modulation. A commercial ultrasound transducer at 20 MHz is used to characterize a fabricated sensor and detection sensitivity at different optical source wavelength within a resonance spectrum is investigated. Practical use of the sensor at a fixed optical source wavelength is presented. Ultimately, the geometry of the planar sensor structure is suitable for two-dimensional, optical pressure imaging applications such as pressure wave detection and mapping, and ultrasound imaging. PMID:25045203

  9. Characterization of Si3N4/SiO2 optical channel waveguides by photon scanning tunneling microscopy

    NASA Technical Reports Server (NTRS)

    Wang, Yan; Chudgar, Mona H.; Jackson, Howard E.; Miller, Jeffrey S.; De Brabander, Gregory N.; Boyd, Joseph T.

    1993-01-01

    Photon scanning tunneling microscopy (PSTM) is used to characterize Si3N4/Si02 optical channel waveguides being used for integrated optical-micromechanical sensors. PSTM utilizes an optical fiber tapered to a fine point which is piezoelectrically positioned to measure the decay of the evanescent field intensity associated with the waveguide propagating mode. Evanescent field decays are recorded for both ridge channel waveguides and planar waveguide regions. Values for the local effective refractive index are calculated from the data for both polarizations and compared to model calculations.

  10. The cross waveguide grating: proposal, theory and applications.

    PubMed

    Muñoz, Pascual; Pastor, Daniel; Capmany, José

    2005-04-18

    In this paper a novel grating-like integrated optics device is proposed, the Cross Waveguide Grating (XWG). The device is based upon a modified configuration of a traditional Arrayed Waveguide Grating (AWG). The Arrayed Waveguides part is changed, as detailed along this document, giving the device both the ability of multi/demultiplexing and power splitting/coupling. Design examples and transfer function simulations show good agreement with the presented theory. Finally, some of the envisaged applications are outlined.

  11. Ultra-large nonlinear parameter in graphene-silicon waveguide structures.

    PubMed

    Donnelly, Christine; Tan, Dawn T H

    2014-09-22

    Mono-layer graphene integrated with optical waveguides is studied for the purpose of maximizing E-field interaction with the graphene layer, for the generation of ultra-large nonlinear parameters. It is shown that the common approach used to minimize the waveguide effective modal area does not accurately predict the configuration with the maximum nonlinear parameter. Both photonic and plasmonic waveguide configurations and graphene integration techniques realizable with today's fabrication tools are studied. Importantly, nonlinear parameters exceeding 10(4) W(-1)/m, two orders of magnitude larger than that in silicon on insulator waveguides without graphene, are obtained for the quasi-TE mode in silicon waveguides incorporating mono-layer graphene in the evanescent part of the optical field. Dielectric loaded surface plasmon polariton waveguides incorporating mono-layer graphene are observed to generate nonlinear parameters as large as 10(5) W(-1)/m, three orders of magnitude larger than that in silicon on insulator waveguides without graphene. The ultra-large nonlinear parameters make such waveguides promising platforms for nonlinear integrated optics at ultra-low powers, and for previously unobserved nonlinear optical effects to be studied in a waveguide platform.

  12. Method and apparatus of wide-angle optical beamsteering from a nanoantenna phased array

    DOEpatents

    Davids, Paul; DeRose, Christopher; Rakich, Peter Thomas

    2015-08-11

    An optical beam-steering apparatus is provided. The apparatus includes one or more optical waveguides and at least one row of metallic nanoantenna elements overlying and electromagnetically coupled to a respective waveguide. In each such row, individual nanoantenna elements are spaced apart along an optical propagation axis of the waveguide so that there is an optical propagation phase delay between successive pairs of nanoantenna elements along the row. The apparatus also includes a respective single electric heating element in thermal contact with each of the waveguides. Each heating element is arranged to heat, substantially uniformly, at least that portion of its waveguide that directly underlies the corresponding row of nanoantenna elements.

  13. Novel optical interconnect devices and coupling methods applying self-written waveguide technology

    NASA Astrophysics Data System (ADS)

    Nakama, Kenichi; Mikami, Osamu

    2011-05-01

    For the use in cost-effective optical interconnection of opt-electronic printed wiring boards (OE-PWBs), we have developed novel optical interconnect devices and coupling methods simplifying board to board optical interconnect. All these are based on the self-written waveguide (SWW) technology by the mask-transfer method with light-curable resin. This method enables fabrication of arrayed M × N optical channels at one shot of UV light. Very precise patterns, as an example, optical rod with diameters of 50μm to 500μm, can be easily fabricated. The length of the fabricated patterns ,, typically up to about 1000μm , can be controlled by a spacer placed between the photomask and the substrate. Using these technologies, several new optical interfaces have been demonstrated. These are a chip VCSEL with an optical output rod and new coupling methods of "plug-in" alignment and "optical socket" based on SWW.

  14. Biosensing operations based on whispering-gallery-mode optical cavities in single 1.0-µm diameter hexagonal GaN microdisks grown by radio-frequency plasma-assisted molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Kouno, Tetsuya; Sakai, Masaru; Kishino, Katsumi; Hara, Kazuhiko

    2016-05-01

    Biosensing operations based on a whispering-gallery-mode optical cavity in a single hexagonal GaN microdisk of approximately 1.0 µm diameter were demonstrated here. The sharp resonant peak in the photoluminescence spectrum obtained from the microdisk in aqueous sucrose solution redshifts with a change in sucrose concentration. The results indicate that an extremely small microdisk could be used as an optical transducer for sensing sugar, namely, as a biosensor. Furthermore, we investigate the relationship between the diameter of the microdisk and the sensitivity of the biosensor.

  15. Single mode tapered fiber-optic interferometer based refractive index sensor and its application to protein sensing.

    PubMed

    Yadav, T K; Narayanaswamy, R; Abu Bakar, M H; Kamil, Y Mustapha; Mahdi, M A

    2014-09-22

    We demonstrate refractive index sensors based on single mode tapered fiber and its application as a biosensor. We utilize this tapered fiber optic biosensor, operating at 1550 nm, for the detection of protein (gelatin) concentration in water. The sensor is based on the spectroscopy of mode coupling based on core modes-fiber cladding modes excited by the fundamental core mode of an optical fiber when it transitions into tapered regions from untapered regions. The changes are determined from the wavelength shift of the transmission spectrum. The proposed fiber sensor has sensitivity of refractive index around 1500 nm/RIU and for protein concentration detection, its highest sensitivity is 2.42141 nm/%W/V.

  16. Rectification of light refraction in curved waveguide arrays.

    PubMed

    Longhi, Stefano

    2009-02-15

    An "optical ratchet" for discretized light in photonic lattices, which enables observing rectification of light refraction at any input beam conditions, is theoretically presented, and a possible experimental implementation based on periodically curved zigzag waveguide arrays is proposed.

  17. Spatially Modulated Gain Waveguide Electro-Optic Laser

    DTIC Science & Technology

    2013-08-09

    1997, pp 1223-1226. 5. Y. Li, S. M. Goldwasser, P. Herczfeld, L.M. Narducci, "Dynamics of an electro-optically tunable microchip laser ", IEEE...TYPE Final 3. DATES COVERED (From 7/2/2010-5-10-2013 To) 4. TITLE AND SUBTITLE Spatially modulated gain waveguide electro-optic laser 5a...optical waveguides laser on LiNb03 substrate. The main goal of this work is to implement an active LiNb03 waveguide with the desired spatially modulated

  18. Nanowires and nanoribbons as subwavelength optical waveguides and their use as components in photonic circuits and devices

    DOEpatents

    Yang, Peidong; Law, Matt; Sirbuly, Donald J.; Johnson, Justin C.; Saykally, Richard; Fan, Rong; Tao, Andrea

    2012-10-02

    Nanoribbons and nanowires having diameters less than the wavelength of light are used in the formation and operation of optical circuits and devices. Such nanostructures function as subwavelength optical waveguides which form a fundamental building block for optical integration. The extraordinary length, flexibility and strength of these structures enable their manipulation on surfaces, including the precise positioning and optical linking of nanoribbon/wire waveguides and other nanoribbon/wire elements to form optical networks and devices. In addition, such structures provide for waveguiding in liquids, enabling them to further be used in other applications such as optical probes and sensors.

  19. Optical trapping and propulsion of red blood cells on waveguide surfaces.

    PubMed

    Ahluwalia, Balpreet Singh; McCourt, Peter; Huser, Thomas; Hellesø, Olav Gaute

    2010-09-27

    We have studied optical trapping and propulsion of red blood cells in the evanescent field of optical waveguides. Cell propulsion is found to be highly dependent on the biological medium and serum proteins the cells are submerged in. Waveguides made of tantalum pentoxide are shown to be efficient for cell propulsion. An optical propulsion velocity of up to 
6 µm/s on a waveguide with a width of ~6 µm is reported. Stable optical trapping and propulsion of cells during transverse flow is also reported.

  20. Optical NAND gate

    DOEpatents

    Skogen, Erik J [Albuquerque, NM; Raring, James [Goleta, CA; Tauke-Pedretti, Anna [Albuquerque, NM

    2011-08-09

    An optical NAND gate is formed from two pair of optical waveguide devices on a substrate, with each pair of the optical waveguide devices consisting of an electroabsorption modulator and a photodetector. One pair of the optical waveguide devices is electrically connected in parallel to operate as an optical AND gate; and the other pair of the optical waveguide devices is connected in series to operate as an optical NOT gate (i.e. an optical inverter). The optical NAND gate utilizes two digital optical inputs and a continuous light input to provide a NAND function output. The optical NAND gate can be formed from III-V compound semiconductor layers which are epitaxially deposited on a III-V compound semiconductor substrate, and operates at a wavelength in the range of 0.8-2.0 .mu.m.

  1. Protein Sensors Based on Optical Ring Resonators

    NASA Technical Reports Server (NTRS)

    Lin, Ying; Ksendzov, Alexander

    2006-01-01

    Prototype transducers based on integrated optical ring resonators have been demonstrated to be useful for detecting the protein avidin in extremely dilute solutions. In an experiment, one of the transducers proved to be capable of indicating the presence of avidin at a concentration of as little as 300 pM in a buffer solution a detection sensitivity comparable to that achievable by previously reported protein-detection techniques. These transducers are serving as models for the further development of integrated-optics sensors for detecting small quantities of other proteins and protein-like substances. The basic principle of these transducers was described in Chemical Sensors Based on Optical Ring Resonators (NPO-40601), NASA Tech Briefs, Vol. 29, No. 10 (October 2005), page 32. The differences between the present transducers and the ones described in the cited prior article lie in details of implementation of the basic principle. As before, the resonator in a transducer of the present type is a closed-circuit dielectric optical waveguide. The outermost layer of this waveguide, analogous to the optical cladding layer on an optical fiber, consists of a layer comprising sublayers having indices of refraction lower than that of the waveguide core. The outermost sublayer absorbs the chemical of interest (in this case, avidin). The index of refraction of the outermost sublayer changes with the concentration of absorbed avidin. The resonator is designed to operate with relatively strong evanescent-wave coupling between the outer sublayer and the electromagnetic field propagating along the waveguide core. By virtue of this coupling, the chemically induced change in the index of refraction of the outermost sublayer causes a measurable change in the spectrum of the resonator output.

  2. A proposal for digital electro-optic switches with free-carrier dispersion effect and Goos-Hanchen shift in silicon-on-insulator waveguide corner mirror

    NASA Astrophysics Data System (ADS)

    Sun, DeGui

    2013-09-01

    In a silicon-on-insulator (SOI) waveguide corner mirror (WCM) structure, with the quantum process of a frustrated total internal reflection (FTIR) phenomenon and the time delay principle in the two-dimensional potential barrier tunneling process of a mass of particles, we derive an accurate physical model for the Goos-Hanchen (GH) shift of optical guided-mode in the FTIR process, and in principle match the GH shift jumping states with the independent guided-modes. Then, we propose and demonstrate a new regime of 1 × N digital optical switches with a matching state between the free-carrier dispersion (FCD) based refractive index modulation (RIM) of silicon to create a GH shift jumping function of a photonic signal at the reflecting interface and the independent guided-modes in the FTIR process, where a MOS-capacitor type electro-optic modulation regime is proposed and discussed to realize an effective FCD-based RIM. At the critical matching state, i.e., the incident of an optical beam is at the vicinity of Brewster angle in the WCM, a mini-change of refractive index of waveguide material can cause a great jump of GH shift along the FTIR reflecting interface, and further a 1 × N digital optical switching process could be realized. For a 350-500 nm single-mode rib waveguide made on the 220 nm CMOS-compatible SOI substrate and with the FCD effect based RIM of silicon crystal, a concentration variation of 1018-1019 cm-3 has caused a 0.5-2.5 μm GH shift of reflected beam, which is at 2-5 times of a mode-size and hence radically convinces an optical switching function with a 1 × 3-1 × 10 scale.

  3. Far infrared pump injection using an alumina waveguide

    NASA Astrophysics Data System (ADS)

    Nedvidek, F. J.; Kucerovsky, Z.; Brannen, Eric

    1987-01-01

    An alumina waveguide extension is employed to channel infrared radiation from a CO2 waveguide laser into an optically pumped far IR waveguide laser resonator in order to obtain far IR lasing with methyl alcohol and other media. Low pump transmission losses and efficient free space coupling are possible with proper choice of waveguide bore. The technique compares favorably with other injection schemes using refractive optics, and it offers greater flexibility, easier alignment, and less expense than optical arrangements using lenses.

  4. Fabrication and characterization of carbon/oxygen-implanted waveguides in Nd3+-doped phosphate glasses

    NASA Astrophysics Data System (ADS)

    Liu, Chun-Xiao; Xu, Jun; Fu, Li-Li; Zheng, Rui-Lin; Zhou, Zhi-Guang; Li, Wei-Nan; Guo, Hai-Tao; Lin, She-Bao; Wei, Wei

    2015-06-01

    Optical planar waveguides in Nd3+-doped phosphate glasses are fabricated by a 6.0-MeV carbon ion implantation with a dose of 6.0×1014 ions/cm2 and a 6.0-MeV oxygen ion implantation at a fluence of 6.0×1014 ions/cm2, respectively. The guided modes and the corresponding effective refractive indices were measured by a modal 2010 prism coupler. The refractive index profiles of the waveguides were analyzed based on the stopping and range of ions in matter and the RCM reflectivity calculation method. The near-field light intensity distributions were measured and simulated by an end-face coupling method and a finite-difference beam propagation method, respectively. The comparison of optical properties between the carbon-implanted waveguide and the oxygen-implanted waveguide was carried out. The microluminescence and Raman spectroscopy investigations reveal that fluorescent properties of Nd3+ ions and glass microstructure are well preserved in the waveguide region, which suggests that the carbon/oxygen-implanted waveguide is a good candidate for integrated photonic devices.

  5. Design of a terahertz parametric oscillator based on a resonant cavity in a terahertz waveguide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saito, K., E-mail: k-saito@material.tohoku.ac.jp; Oyama, Y.; Tanabe, T.

    We demonstrate ns-pulsed pumping of terahertz (THz) parametric oscillations in a quasi-triply resonant cavity in a THz waveguide. The THz waves, down converted through parametric interactions between the pump and signal waves at telecom frequencies, are confined to a GaP single mode ridge waveguide. By combining the THz waveguide with a quasi-triply resonant cavity, the nonlinear interactions can be enhanced. A low threshold pump intensity for parametric oscillations can be achieved in the cavity waveguide. The THz output power can be maximized by optimizing the quality factors of the cavity so that an optical to THz photon conversion efficiency, η{submore » p}, of 0.35, which is near the quantum-limit level, can be attained. The proposed THz optical parametric oscillator can be utilized as an efficient and monochromatic THz source.« less

  6. Efficient Fluorescence Resonance Energy Transfer between Quantum Dots and Gold Nanoparticles Based on Porous Silicon Photonic Crystal for DNA Detection.

    PubMed

    Zhang, Hongyan; Lv, Jie; Jia, Zhenhong

    2017-05-10

    A novel assembled biosensor was prepared for detecting 16S rRNA, a small-size persistent specific for Actinobacteria. The mechanism of the porous silicon (PS) photonic crystal biosensor is based on the fluorescence resonance energy transfer (FRET) between quantum dots (QDs) and gold nanoparticles (AuNPs) through DNA hybridization, where QDs act as an emission donor and AuNPs serve as a fluorescence quencher. Results showed that the photoluminescence (PL) intensity of PS photonic crystal was drastically increased when the QDs-conjugated probe DNA was adhered to the PS layer by surface modification using a standard cross-link chemistry method. The PL intensity of QDs was decreased when the addition of AuNPs-conjugated complementary 16S rRNA was dropped onto QDs-conjugated PS. Based on the analysis of different target DNA concentration, it was found that the decrease of the PL intensity showed a good linear relationship with complementary DNA concentration in a range from 0.25 to 10 μM, and the detection limit was 328.7 nM. Such an optical FRET biosensor functions on PS-based photonic crystal for DNA detection that differs from the traditional FRET, which is used only in liquid. This method will benefit the development of a new optical FRET label-free biosensor on Si substrate and has great potential in biochips based on integrated optical devices.

  7. Gallium arsenide based surface plasmon resonance for glucose monitoring

    NASA Astrophysics Data System (ADS)

    Patil, Harshada; Sane, Vani; Sriram, G.; Indumathi, T. S; Sharan, Preeta

    2015-07-01

    The recent trends in the semiconductor and microwave industries has enabled the development of scalable microfabrication technology which produces a superior set of performance as against its counterparts. Surface Plasmon Resonance (SPR) based biosensors are a special class of optical sensors that become affected by electromagnetic waves. It is found that bio-molecular recognition element immobilized on the SPR sensor surface layer reveals a characteristic interaction with various sample solutions during the passage of light. The present work revolves around developing painless glucose monitoring systems using fluids containing glucose like saliva, urine, sweat or tears instead of blood samples. Non-invasive glucose monitoring has long been simulated using label free detection mechanisms and the same concept is adapted. In label-free detection, target molecules are not labeled or altered, and are detected in their natural forms. Label-free detection mechanisms involves the measurement of refractive index (RI) change induced by molecular interactions. These interactions relates the sample concentration or surface density, instead of total sample mass. After simulation it has been observed that the result obtained is highly accurate and sensitive. The structure used here is SPR sensor based on channel waveguide. The tools used for simulation are RSOFT FULLWAVE, MEEP and MATLAB etc.

  8. Microbubble-assisted optofluidic control using a photothermal waveguide

    NASA Astrophysics Data System (ADS)

    Cheng, YuPeng; Yang, JianXin; Li, ZongBao; Zhu, DeBin; Cai, Xiang; Hu, Xiaowen; Huang, Wen; Xing, XiaoBo

    2017-10-01

    A convenient and easily controllable microfluidic system was proposed based on a photothermal device. Here, graphene oxide was assembled on an optical waveguide, which could serve as a miniature heat source to generate a microbubble and to control dynamic behaviors of flow by adjusting optical power at the micrometer scale. Micro/nanoparticles were used to demonstrate the trace of fluid flow around the microbubble, which displayed the ability of the flow to capture, transmit, and rotate particles in thermal convection. Correspondingly, three-dimensional theoretical simulation combining thermodynamics with hydrodynamics analyzed the distribution of the velocity field induced by the microbubble for collection and driving of particles. Furthermore, the photothermal waveguide would be developed into a microbubble-based device in the manipulation or transmission of micro/nanoparticles.

  9. A Photonic 1 × 4 Power Splitter Based on Multimode Interference in Silicon–Gallium-Nitride Slot Waveguide Structures

    PubMed Central

    Malka, Dror; Danan, Yossef; Ramon, Yehonatan; Zalevsky, Zeev

    2016-01-01

    In this paper, a design for a 1 × 4 optical power splitter based on the multimode interference (MMI) coupler in a silicon (Si)–gallium nitride (GaN) slot waveguide structure is presented—to our knowledge, for the first time. Si and GaN were found as suitable materials for the slot waveguide structure. Numerical optimizations were carried out on the device parameters using the full vectorial-beam propagation method (FV-BPM). Simulation results show that the proposed device can be useful to divide optical signal energy uniformly in the C-band range (1530–1565 nm) into four output ports with low insertion losses (0.07 dB). PMID:28773638

  10. Toxin detection using a fiber-optic-based biosensor

    NASA Astrophysics Data System (ADS)

    Ogert, Robert A.; Shriver-Lake, Lisa C.; Ligler, Frances S.

    1993-05-01

    Using an evanescent wave fiber optic-based biosensor developed at Naval Research Laboratory, ricin toxin can be detected in the low ng/ml range. Sensitivity was established at 1 - 5 ng/ml using a two-step assay. The two-step assay showed enhanced signal levels in comparison to a one-step assay. A two-step assay utilizes a 10 minute incubation of an immobilized affinity purified anti-ricin antibody fiber optic probe in the ricin sample before placement in a solution of fluorophore-labeled goat anti-ricin antibodies. The specific fluorescent signal is obtained by the binding of the fluorophore-labeled antibodies to ricin which is bound by the immobilized antibodies on the fiber optic probe. The toxin can be detected directly from urine and river water using this fiber optic assay.

  11. Photorefractive waveguides in oxide crystals: fabrication, properties, and applications

    NASA Astrophysics Data System (ADS)

    Kip, D.

    1998-08-01

    In several oxide crystals the refractive index can be changed by inhomogeneous illumination, and these photorefractive properties have allowed for a wide variety of applications in optical data storage and dynamic holography. The high light intensities that are inherent in waveguide geometries make it relatively easy to observe photorefractive effects in waveguide structures, too. On the one hand, these effects are feared as optical damage, as they can degrade the performance of integrated optical devices. On the other hand, optical wave mixing in photorefractive waveguides is of considerable interest for the development of nonlinear optical components. A review of the results of recent research on the fabrication, investigation, and applications of photorefractive waveguides is given. The formation and photorefractive properties of LiNbO3, LiTaO3, BaTiO3, KNbO3, SrxBa1-xNb2O6 (0.25hxА.75, SBN), and Bi12(Si,Ti,Ge)O20 (BSO, BTO, BGO) waveguides are discussed. Furthermore, the suitability of photorefractive waveguides for nonlinear optical components is demonstrated in some examples.

  12. Optical pumping in a whispering mode optical waveguide

    DOEpatents

    Kurnit, Norman A.

    1984-01-01

    A device and method for optical pumping in a whispering mode optical waveguide. Both a helical ribbon and cylinder are disclosed which incorporate an additional curvature for confining the beam to increase intensity. An optical pumping medium is disposed in the optical path of the beam as it propagates along the waveguide. Optical pumping is enhanced by the high intensities of the beam and long interaction pathlengths which are achieved in a small volume.

  13. Nonlinear digital out-of-plane waveguide coupler based on nonlinear scattering of a single graphene layer

    NASA Astrophysics Data System (ADS)

    Asadi, Reza; Ouyang, Zhengbiao

    2018-03-01

    A new mechanism for out-of-plane coupling into a waveguide is presented and numerically studied based on nonlinear scattering of a single nano-scale Graphene layer inside the waveguide. In this mechanism, the refractive index nonlinearity of Graphene and nonhomogeneous light intensity distribution occurred due to the interference between the out-of-plane incident pump light and the waveguide mode provide a virtual grating inside the waveguide, coupling the out-of-plane pump light into the waveguide. It has been shown that the coupling efficiency has two distinct values with high contrast around a threshold pump intensity, providing suitable condition for digital optical applications. The structure operates at a resonance mode due to band edge effect, which enhances the nonlinearity and decreases the required threshold intensity.

  14. Peptide Integrated Optics.

    PubMed

    Handelman, Amir; Lapshina, Nadezda; Apter, Boris; Rosenman, Gil

    2018-02-01

    Bio-nanophotonics is a wide field in which advanced optical materials, biomedicine, fundamental optics, and nanotechnology are combined and result in the development of biomedical optical chips. Silk fibers or synthetic bioabsorbable polymers are the main light-guiding components. In this work, an advanced concept of integrated bio-optics is proposed, which is based on bioinspired peptide optical materials exhibiting wide optical transparency, nonlinear and electrooptical properties, and effective passive and active waveguiding. Developed new technology combining bottom-up controlled deposition of peptide planar wafers of a large area and top-down focus ion beam lithography provides direct fabrication of peptide optical integrated circuits. Finding a deep modification of peptide optical properties by reconformation of biological secondary structure from native phase to β-sheet architecture is followed by the appearance of visible fluorescence and unexpected transition from a native passive optical waveguiding to an active one. Original biocompatibility, switchable regimes of waveguiding, and multifunctional nonlinear optical properties make these new peptide planar optical materials attractive for application in emerging technology of lab-on-biochips, combining biomedical photonic and electronic circuits toward medical diagnosis, light-activated therapy, and health monitoring. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Quantitative detection of bovine and porcine gelatin difference using surface plasmon resonance based biosensor

    NASA Astrophysics Data System (ADS)

    Wardani, Devy P.; Arifin, Muhammad; Suharyadi, Edi; Abraha, Kamsul

    2015-05-01

    Gelatin is a biopolymer derived from collagen that is widely used in food and pharmaceutical products. Due to some religion restrictions and health issues regarding the gelatin consumption which is extracted from certain species, it is necessary to establish a robust, reliable, sensitive and simple quantitative method to detect gelatin from different parent collagen species. To the best of our knowledge, there has not been a gelatin differentiation method based on optical sensor that could detect gelatin from different species quantitatively. Surface plasmon resonance (SPR) based biosensor is known to be a sensitive, simple and label free optical method for detecting biomaterials that is able to do quantitative detection. Therefore, we have utilized SPR-based biosensor to detect the differentiation between bovine and porcine gelatin in various concentration, from 0% to 10% (w/w). Here, we report the ability of SPR-based biosensor to detect difference between both gelatins, its sensitivity toward the gelatin concentration change, its reliability and limit of detection (LOD) and limit of quantification (LOQ) of the sensor. The sensor's LOD and LOQ towards bovine gelatin concentration are 0.38% and 1.26% (w/w), while towards porcine gelatin concentration are 0.66% and 2.20% (w/w), respectively. The results show that SPR-based biosensor is a promising tool for detecting gelatin from different raw materials quantitatively.

  16. Field of view of limitations in see-through HMD using geometric waveguides.

    PubMed

    DeHoog, Edward; Holmstedt, Jason; Aye, Tin

    2016-08-01

    Geometric waveguides are being integrated into head-mounted display (HMD) systems, where having see-through capability in a compact, lightweight form factor is required. We developed methods for determining the field of view (FOV) of such waveguide HMD systems and have analytically derived the FOV for waveguides using planar and curved geometries. By using real ray-tracing methods, we are able to show how the geometry and index of refraction of the waveguide, as well as the properties of the coupling optics, impact the FOV. Use of this analysis allows one to determine the maximum theoretical FOV of a planar or curved waveguide-based system.

  17. Board-to-board optical interconnection using novel optical plug and slot

    NASA Astrophysics Data System (ADS)

    Cho, In K.; Yoon, Keun Byoung; Ahn, Seong H.; Kim, Jin Tae; Lee, Woo Jin; Shin, Kyoung Up; Heo, Young Un; Park, Hyo Hoon

    2004-10-01

    A novel optical PCB with transmitter/receiver system boards and optical bakcplane was prepared, which is board-to-board interconnection by optical plug and slot. We report an 8Gb/s PRBS NRZ data transmission between transmitter system board and optical backplane embedded multimode polymeric waveguide arrays. The basic concept of ETRI's optical PCB is as follows; 1) Metal optical bench is integrated with optoelectronic devices, driver and receiver circuits, polymeric waveguide and access line PCB module. 2) Multimode polymeric waveguide inside an optical backplane, which is embedded into PCB. 3) Optical slot and plug for high-density(channel pitch : 500um) board-to-board interconnection. The polymeric waveguide technology can be used for transmission of data on transmitter/ receiver system boards and for backplane interconnections. The main components are low-loss tapered polymeric waveguides and a novel optical plug and slot for board-to-board interconnections, respectively. The optical PCB is characteristic of low coupling loss, easy insertion/extraction of the boards and, especially, reliable optical coupling unaffected from external environment after board insertion.

  18. Encapsulated Optically Responsive Cell Systems: Toward Smart Implants in Biomedicine.

    PubMed

    Boss, Christophe; Bouche, Nicolas; De Marchi, Umberto

    2018-04-01

    Managing increasingly prevalent chronic diseases will require close continuous monitoring of patients. Cell-based biosensors may be used for implantable diagnostic systems to monitor health status. Cells are indeed natural sensors in the body. Functional cellular systems can be maintained in the body for long-term implantation using cell encapsulation technology. By taking advantage of recent progress in miniaturized optoelectronic systems, the genetic engineering of optically responsive cells may be combined with cell encapsulation to generate smart implantable cell-based sensing systems. In biomedical research, cell-based biosensors may be used to study cell signaling, therapeutic effects, and dosing of bioactive molecules in preclinical models. Today, a wide variety of genetically encoded fluorescent sensors have been developed for real-time imaging of living cells. Here, recent developments in genetically encoded sensors, cell encapsulation, and ultrasmall optical systems are highlighted. The integration of these components in a new generation of biosensors is creating innovative smart in vivo cell-based systems, bringing novel perspectives for biomedical research and ultimately allowing unique health monitoring applications. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Fluorescent fluid interface position sensor

    DOEpatents

    Weiss, Jonathan D.

    2004-02-17

    A new fluid interface position sensor has been developed, which is capable of optically determining the location of an interface between an upper fluid and a lower fluid, the upper fluid having a larger refractive index than a lower fluid. The sensor functions by measurement, of fluorescence excited by an optical pump beam which is confined within a fluorescent waveguide where that waveguide is in optical contact with the lower fluid, but escapes from the fluorescent waveguide where that waveguide is in optical contact with the upper fluid.

  20. A fiber-optic sorbitol biosensor based on NADH fluorescence detection toward rapid diagnosis of diabetic complications.

    PubMed

    Gessei, Tomoko; Arakawa, Takahiro; Kudo, Hiroyuki; Mitsubayashi, Kohji

    2015-09-21

    Accumulation of sorbitol in the tissue is known to cause microvascular diabetic complications. In this paper, a fiber-optic biosensor for sorbitol which is used as a biomarker of diabetic complications was developed and tested. The biosensor used a sorbitol dehydrogenase from microorganisms of the genus Flavimonas with high substrate specificity and detected the fluorescence of reduced nicotinamide adenine dinucleotide (NADH) by the enzymatic reaction. An ultraviolet light emitting diode (UV-LED) was used as the excitation light source of NADH. The fluorescence of NADH was detected using a spectrometer or a photomultiplier tube (PMT). The UV-LED and the photodetector were coupled using a Y-shaped optical fiber. In the experiment, an optical fiber probe with a sorbitol dehydrogenase immobilized membrane was placed in a cuvette filled with a phosphate buffer containing the oxidized form of nicotinamide adenine dinucleotide (NAD(+)). The changes in NADH fluorescence intensity were measured after adding a standard sorbitol solution. According to the experimental assessment, the calibration range of the sorbitol biosensor systems using a spectrometer and a PMT was 5.0-1000 μmol L(-1) and 1.0-1000 μmol L(-1), respectively. The sorbitol biosensor system using the sorbitol dehydrogenase from microorganisms of the genus Flavimonas has high selectivity and sensitivity compared with that from sheep liver. The sorbitol biosensor allows for point-of-care testing applications or daily health care tests for diabetes patients.

  1. FDTD modeling of anisotropic nonlinear optical phenomena in silicon waveguides.

    PubMed

    Dissanayake, Chethiya M; Premaratne, Malin; Rukhlenko, Ivan D; Agrawal, Govind P

    2010-09-27

    A deep insight into the inherent anisotropic optical properties of silicon is required to improve the performance of silicon-waveguide-based photonic devices. It may also lead to novel device concepts and substantially extend the capabilities of silicon photonics in the future. In this paper, for the first time to the best of our knowledge, we present a three-dimensional finite-difference time-domain (FDTD) method for modeling optical phenomena in silicon waveguides, which takes into account fully the anisotropy of the third-order electronic and Raman susceptibilities. We show that, under certain realistic conditions that prevent generation of the longitudinal optical field inside the waveguide, this model is considerably simplified and can be represented by a computationally efficient algorithm, suitable for numerical analysis of complex polarization effects. To demonstrate the versatility of our model, we study polarization dependence for several nonlinear effects, including self-phase modulation, cross-phase modulation, and stimulated Raman scattering. Our FDTD model provides a basis for a full-blown numerical simulator that is restricted neither by the single-mode assumption nor by the slowly varying envelope approximation.

  2. A systematic optimization of design parameters in strained silicon waveguides to further enhance the linear electro-optic effect

    NASA Astrophysics Data System (ADS)

    Olivares, Irene; Angelova, Todora I.; Pinilla-Cienfuegos, Elena; Sanchis, Pablo

    2016-05-01

    The electro-optic Pockels effect may be generated in silicon photonics structures by breaking the crystal symmetry by means of a highly stressing cladding layer (typically silicon nitride, SiN) deposited on top of the silicon waveguide. In this work, the influence of the waveguide parameters on the strain distribution and its overlap with the optical mode to enhance the Pockels effect has been analyzed. The optimum waveguide structure have been designed based on the definition and quantification of a figure of merit. The fabrication of highly stressing SiN layers by PECVD has also been optimized to characterize the designed structures. The residual stress has been controlled during the growth process by analyzing the influence of the main deposition parameters. Therefore, two identical samples with low and high stress conditions were fabricated and electro-optically characterized to test the induced Pockels effect and the influence of carrier effects. Electro-optical modulation was only measured in the sample with the high stressing SiN layer that could be attributed to the Pockels effect. Nevertheless, the influence of carriers were also observed thus making necessary additional experiments to decouple both effects.

  3. Novel optoelectronic devices; Proceedings of the Meeting, The Hague, Netherlands, Mar. 31-Apr. 2, 1987

    NASA Technical Reports Server (NTRS)

    Adams, Michael J. (Editor)

    1987-01-01

    The present conference on novel optoelectronics discusses topics in the state-of-the-art in this field in the Netherlands, quantum wells, integrated optics, nonlinear optical devices and fiber-optic-based devices, ultrafast optics, and nonlinear optics and optical bistability. Attention is given to the production of fiber-optics for telecommunications by means of PCVD, lifetime broadening in quantum wells, nonlinear multiple quantum well waveguide devices, tunable single-wavelength lasers, an Si integrated waveguiding polarimeter, and an electrooptic light modulator using long-range surface plasmons. Also discussed are backward-wave couplers and reflectors, a wavelength-selective all-fiber switching matrix, the impact of ultrafast optics in high-speed electronics, the physics of low energy optical switching, and all-optical logical elements for optical processing.

  4. Arrays of strongly coupled atoms in a one-dimensional waveguide

    NASA Astrophysics Data System (ADS)

    Ruostekoski, Janne; Javanainen, Juha

    2017-09-01

    We study the cooperative optical coupling between regularly spaced atoms in a one-dimensional waveguide using decompositions to subradiant and super-radiant collective excitation eigenmodes, direct numerical solutions, and analytical transfer-matrix methods. We illustrate how the spectrum of transmitted light through the waveguide, including the emergence of narrow Fano resonances, can be understood by the resonance features of the eigenmodes. We describe a method based on super-radiant and subradiant modes to engineer the optical response of the waveguide and to store light. The stopping of light is obtained by transferring an atomic excitation to a subradiant collective mode with the zero radiative resonance linewidth by controlling the level shift of an atom in the waveguide. Moreover, we obtain an exact analytic solution for the transmitted light through the waveguide for the case of a regular lattice of atoms and provide a simple description of how the light transmission may present large resonance shifts when the lattice spacing is close, but not exactly equal, to half of the wavelength of the light. Experimental imperfections such as fluctuations of the positions of the atoms and loss of light from the waveguide are easily quantified in the numerical simulations, which produce the natural result that the optical response of the atomic array tends toward the response of a gas with random atomic positions.

  5. FIBER-OPTIC BIOSENSOR FOR DIRECT DETERMINATION OF ORGANOPHOSPHATE NERVE AGENTS. (R823663)

    EPA Science Inventory

    A fiber-optic enzyme biosensor for the direct measurement of organophosphate nerve
    agents was developed. The basic element of this biosensor is organophosphorus hydrolase
    immobilized on a nylon membrane and attached to the common end of a bifurcated optical fiber
    bundle....

  6. Non-invasive, in vitro analysis of islet insulin production enabled by an optical porous silicon biosensor.

    PubMed

    Chhasatia, Rinku; Sweetman, Martin J; Harding, Frances J; Waibel, Michaela; Kay, Tom; Thomas, Helen; Loudovaris, Thomas; Voelcker, Nicolas H

    2017-05-15

    A label-free porous silicon (pSi) based, optical biosensor, using both an antibody and aptamer bioreceptor motif has been developed for the detection of insulin. Two parallel biosensors were designed and optimised independently, based on each bioreceptor. Both bioreceptors were covalently attached to a thermally hydrosilylated pSi surface though amide coupling, with unreacted surface area rendered stable and low fouling by incorporation of PEG moieties. The insulin detection ability of each biosensor was determined using interferometric reflectance spectroscopy, using a range of different media both with and without serum. Sensing performance was compared in terms of response value, response time and limit of detection (LOD) for each platform. In order to demonstrate the capability of the best performing biosensor to detect insulin from real samples, an in vitro investigation with the aptamer-modified surface was performed. This biosensor was exposed to buffer conditioned by glucose-stimulated human islets, with the result showing a positive response and a high degree of selectivity towards insulin capture. The obtained results correlated well with the ELISA used in the clinic for assaying glucose-stimulated insulin release from donor islets. We anticipate that this type of sensor can be applied as a rapid point-of-use biosensor to assess the quality of donor islets in terms of their insulin production efficiency, prior to transplantation. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Electrochemical Biosensors - Sensor Principles and Architectures

    PubMed Central

    Grieshaber, Dorothee; MacKenzie, Robert; Vörös, Janos; Reimhult, Erik

    2008-01-01

    Quantification of biological or biochemical processes are of utmost importance for medical, biological and biotechnological applications. However, converting the biological information to an easily processed electronic signal is challenging due to the complexity of connecting an electronic device directly to a biological environment. Electrochemical biosensors provide an attractive means to analyze the content of a biological sample due to the direct conversion of a biological event to an electronic signal. Over the past decades several sensing concepts and related devices have been developed. In this review, the most common traditional techniques, such as cyclic voltammetry, chronoamperometry, chronopotentiometry, impedance spectroscopy, and various field-effect transistor based methods are presented along with selected promising novel approaches, such as nanowire or magnetic nanoparticle-based biosensing. Additional measurement techniques, which have been shown useful in combination with electrochemical detection, are also summarized, such as the electrochemical versions of surface plasmon resonance, optical waveguide lightmode spectroscopy, ellipsometry, quartz crystal microbalance, and scanning probe microscopy. The signal transduction and the general performance of electrochemical sensors are often determined by the surface architectures that connect the sensing element to the biological sample at the nanometer scale. The most common surface modification techniques, the various electrochemical transduction mechanisms, and the choice of the recognition receptor molecules all influence the ultimate sensitivity of the sensor. New nanotechnology-based approaches, such as the use of engineered ion-channels in lipid bilayers, the encapsulation of enzymes into vesicles, polymersomes, or polyelectrolyte capsules provide additional possibilities for signal amplification. In particular, this review highlights the importance of the precise control over the delicate interplay between surface nano-architectures, surface functionalization and the chosen sensor transducer principle, as well as the usefulness of complementary characterization tools to interpret and to optimize the sensor response. PMID:27879772

  8. Fabrication of planar optical waveguides by 6.0 MeV silicon ion implantation in Nd-doped phosphate glasses

    NASA Astrophysics Data System (ADS)

    Shen, Xiao-Liang; Dai, Han-Qing; Zhang, Liao-Lin; Wang, Yue; Zhu, Qi-Feng; Guo, Hai-Tao; Li, Wei-Nan; Liu, Chun-Xiao

    2018-04-01

    We report the fabrication of a planar optical waveguide by silicon ion implantation into Nd-doped phosphate glass at an energy of 6.0 MeV and a dose of 5.0 × 1014 ions/cm2. The change in the surface morphology of the glass after the implantation can be clearly observed by scanning electron microscopy. The measurement of the dark mode spectrum of the waveguide is conducted using a prism coupler at 632.8 nm. The refractive index distribution of the waveguide is reconstructed by the reflectivity calculation method. The near-field optical intensity profile of the waveguide is measured using an end-face coupling system. The waveguide with good optical properties on the glass matrix may be valuable for the application of the Nd-doped phosphate glass in integrated optical devices.

  9. Simultaneous detection and determination of mercury (II) and lead (II) ions through the achievement of novel functional nucleic acid-based biosensors.

    PubMed

    Khoshbin, Zahra; Housaindokht, Mohammad Reza; Verdian, Asma; Bozorgmehr, Mohammad Reza

    2018-09-30

    The serious threats of mercury (Hg 2+ ) and lead (Pb 2+ ) ions for the public health makes it important to achieve the detection methods of the ions with high affinity and specificity. Metal ions usually coexist in some environment and foodstuff or clinical samples. Therefore, it is very necessary to develop a fast and simple method for simultaneous monitoring the amount of metal ions, especially when Hg 2+ and Pb 2+ coexist. DNAzyme-based biosensors and aptasensors have been highly regarded for this purpose as two main groups of the functional nucleic acid (FNA)-based biosensors. In this review, we summarize the recent achievements of functional nucleic acid-based biosensors for the simultaneous detection of Hg 2+ and Pb 2+ ions in two main optical and electrochemical groups. The tremendous interest in utilizing the various nanomaterials is also highlighted in the fabrication of the FNA-based biosensors. Finally, some results are presented based on the advantages and disadvantages of the studied FNA-based biosensors to compare their validation. Copyright © 2018 Elsevier B.V. All rights reserved.

  10. Optical pumping in a whispering-mode optical waveguide

    DOEpatents

    Kurnit, N.A.

    1981-08-11

    A device and method for optical pumping in a whispering mode optical waveguide are described. Both a helical ribbon and cylinder are disclosed which incorporate an additional curvature for confining the beam to increase intensity. An optical pumping medium is disposed in the optical path of the beam as it propagates along the waveguide. Optical pumping is enhanced by the high intensities of the beam and long interaction path lengths which are achieved in a small volume.

  11. Board-level optical clock signal distribution using Si CMOS-compatible polyimide-based 1- to 48-fanout H-tree

    NASA Astrophysics Data System (ADS)

    Wu, Linghui; Bihari, Bipin; Gan, Jianhua; Chen, Ray T.; Tang, Suning

    1998-08-01

    Si-CMOS compatible polymer-based waveguides for optoelectronic interconnects and packaging have been fabricated and characterized. A 1-to-48 fanout optoelectronic interconnection layer (OIL) structure based on Ultradel 9120/9020 for the high-speed massive clock signal distribution for a Cray T-90 supercomputer board has been constructed. The OIL employs multimode polymeric channel waveguides in conjunction with surface-normal waveguide output coupler and 1-to-2 splitter. A total insertion loss of 7.98 dB at 850 nm was measured experimentally.

  12. Optical study of Erbium-doped-porous silicon based planar waveguides

    NASA Astrophysics Data System (ADS)

    Najar, A.; Ajlani, H.; Charrier, J.; Lorrain, N.; Haesaert, S.; Oueslati, M.; Haji, L.

    2007-06-01

    Planar waveguides were formed from porous silicon layers obtained on P + substrates. These waveguides were then doped by erbium using an electrochemical method. Erbium concentration in the range 2.2-2.5 at% was determined by energy dispersive X-ray (EDX) analysis performed on SEM cross sections. The refractive index of layers was studied before and after doping and thermal treatments. The photoluminescence of Er 3+ ions in the IR range and the decay curve of the 1.53 μm emission peak were studied as a function of the excitation power. The value of excited Er density was equal to 0.07%. Optical loss contributions were analyzed on these waveguides and the losses were equal to 1.1 dB/cm at 1.55 μm after doping.

  13. Design of compact surface optical coupler based on vertically curved silicon waveguide for high-numerical-aperture single-mode optical fiber

    NASA Astrophysics Data System (ADS)

    Atsumi, Yuki; Yoshida, Tomoya; Omoda, Emiko; Sakakibara, Youichi

    2017-09-01

    A surface optical coupler based on a vertically curved Si waveguide was designed for coupling with high-numerical aperture single-mode optical fibers with a mode-field diameter of 5 µm. This coupler has a quite small device size, with a height of approximately 12 µm, achieved by introducing an effective spot-size converter configured with the combination of an extremely short Si exponential-inverse taper and a dome-structured SiO2 lens formed on the coupler top. The designed coupler shows high-efficiency optical coupling, with a loss of 0.8 dB for TE polarized light, as well as broad-band coupling with a 0.5-dB-loss band of 420 nm.

  14. Stoichiometric Lithium Niobate (SLN) Based Linearized Electro-Optic (EO) Modulator

    DTIC Science & Technology

    2006-01-01

    AFRL-SN-RS-TR-2006-15 Final Technical Report January 2006 STOICHIOMETRIC LITHIUM NIOBATE (SLN) BASED LINEARIZED ELECTRO - OPTIC (EO...LITHIUM NIOBATE (SLN) BASED LINEARIZED ELECTRO - OPTIC (EO) MODULATOR 6. AUTHOR(S) Dr Stuart Kingsley, Dr Sri Sriram 5. FUNDING NUMBERS C...SUBJECT TERMS electro - optic modulator, linearization, directional coupler, variable coupling, optical waveguide, Mach-Zehnder, photonic link, lithium

  15. Fast wavelength calibration method for spectrometers based on waveguide comb optical filter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Zhengang; Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240; Huang, Meizhen, E-mail: mzhuang@sjtu.edu.cn

    2015-04-15

    A novel fast wavelength calibration method for spectrometers based on a standard spectrometer and a double metal-cladding waveguide comb optical filter (WCOF) is proposed and demonstrated. By using the WCOF device, a wide-spectrum beam is comb-filtered, which is very suitable for spectrometer wavelength calibration. The influence of waveguide filter’s structural parameters and the beam incident angle on the comb absorption peaks’ wavelength and its bandwidth are also discussed. The verification experiments were carried out in the wavelength range of 200–1100 nm with satisfactory results. Comparing with the traditional wavelength calibration method based on discrete sparse atomic emission or absorption lines,more » the new method has some advantages: sufficient calibration data, high accuracy, short calibration time, fit for produce process, stability, etc.« less

  16. Investigation of local strain distribution and linear electro-optic effect in strained silicon waveguides.

    PubMed

    Chmielak, Bartos; Matheisen, Christopher; Ripperda, Christian; Bolten, Jens; Wahlbrink, Thorsten; Waldow, Michael; Kurz, Heinrich

    2013-10-21

    We present detailed investigations of the local strain distribution and the induced second-order optical nonlinearity within strained silicon waveguides cladded with a Si₃N₄ strain layer. Micro-Raman Spectroscopy mappings and electro-optic characterization of waveguides with varying width w(WG) show that strain gradients in the waveguide core and the effective second-order susceptibility χ(2)(yyz) increase with reduced w(WG). For 300 nm wide waveguides a mean effective χ(2)(yyz) of 190 pm/V is achieved, which is the highest value reported for silicon so far. To gain more insight into the origin of the extraordinary large optical second-order nonlinearity of strained silicon waveguides numerical simulations of edge induced strain gradients in these structures are presented and discussed.

  17. FIBER AND INTEGRATED OPTICS: Detection of the optical anisotropy in KTP:Rb waveguides

    NASA Astrophysics Data System (ADS)

    Buritskiĭ, K. S.; Dianov, Evgenii M.; Maslov, Vladislav A.; Chernykh, V. A.; Shcherbakov, E. A.

    1990-10-01

    The optical characteristics of channel waveguides made of rubidium-activated potassium titanyl phosphate (KTP:Rb) were determined. The refractive index increment of such waveguides was found to exhibit a considerable anisotropy: Δnx / Δnz approx 2. A deviation of the distribution of the refractive index in a channel waveguide from the model distribution was observed for ion-exchange times in excess of 1 h.

  18. Label-Free Biosensing with High Selectivity in Complex Media using Microtoroidal Optical Resonators

    NASA Astrophysics Data System (ADS)

    Ozgur, Erol; Toren, Pelin; Aktas, Ozan; Huseyinoglu, Ersin; Bayindir, Mehmet

    2015-08-01

    Although label-free biosensors comprised of optical microcavities inherently possess the capability of resolving molecular interactions at individual level, this extreme sensitivity restricts their convenience for large scale applications by inducing vulnerability towards non-specific interactions that readily occur within complex media. Therefore, the use of optical microresonators for biosensing is mostly limited within strictly defined laboratory conditions, instead of field applications as early detection of cancer markers in blood, or identification of contamination in food. Here, we propose a novel surface modification strategy suitable for but not limited to optical microresonator based biosensors, enabling highly selective biosensing with considerable sensitivity as well. Using a robust, silane-based surface coating which is simultaneously protein resistant and bioconjugable, we demonstrate that it becomes possible to perform biosensing within complex media, without compromising the sensitivity or reliability of the measurement. Functionalized microtoroids are successfully shown to resist nonspecific interactions, while simultaneously being used as sensitive biological sensors. This strategy could pave the way for important applications in terms of extending the use of state-of-the-art biosensors for solving problems similar to the aforementioned.

  19. Recent advances in transition-metal dichalcogenides based electrochemical biosensors: A review.

    PubMed

    Wang, Yi-Han; Huang, Ke-Jing; Wu, Xu

    2017-11-15

    Layered transition metal dichalcogenides (TMDCs) comprise a category of two-dimensional (2D) materials that offer exciting properties, including large surface area, metallic and semi-conducting electrical capabilities, and intercalatable morphologies. Biosensors employ biological molecules to recognize the target and utilize output elements which can translate the biorecognition event into electrical, optical or mass-sensitive signals to determine the quantities of the target. TMDCs nanomaterials have been widely applied in various electrochemical biosensors with high sensitivity and selectivity. The marriage of TMDCs and electrochemical biosensors has created many productive sensing strategies for applications in the areas of clinical diagnosis, environmental monitoring and food safety. In recent years, an increasing number of TMDCs-based electrochemical biosensors are reported, suggesting TMDCs offers new possibilities of improving the performance of electrochemical biosensors. This review summarizes recent advances in electrochemical biosensors based on TMDCs for detection of various inorganic and organic analytes in the last five years, including glucose, proteins, DNA, heavy metal, etc. In addition, we also point out the challenges and future perspectives related to the material design and development of TMDCs-based electrochemical biosensors. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Optical waveguides in magneto-optical glasses fabricated by proton implantation

    NASA Astrophysics Data System (ADS)

    Liu, Chun-Xiao; Li, Yu-Wen; Zheng, Rui-Lin; Fu, Li-Li; Zhang, Liao-Lin; Guo, Hai-Tao; Zhou, Zhi-Guang; Li, Wei-Nan; Lin, She-Bao; Wei, Wei

    2016-11-01

    Planar waveguides in magneto-optical glasses (Tb3+-doped aluminum borosilicate glasses) have been produced by a 550-keV proton implantation at a dose of 4.0×1016 ions/cm2 for the first time to our knowledge. After annealing at 260 °C for 1.0 h, the dark-mode spectra and near-field intensity distributions are measured by the prism-coupling and end-face coupling methods. The damage profile, refractive index distribution and light propagation mode of the planar waveguide are numerically calculated by SRIM 2010, RCM and FD-BPM, respectively. The effects of implantation on the structural and optical properties are investigated by Raman and absorption spectra. It suggests that the proton-implanted Tb3+-doped aluminum borosilicate glass waveguide is a good candidate for a waveguide isolator in optical fiber communication and all-optical communication.

  1. Optical waveguides with memory effect using photochromic material for neural network

    NASA Astrophysics Data System (ADS)

    Tanimoto, Keisuke; Amemiya, Yoshiteru; Yokoyama, Shin

    2018-04-01

    An optical neural network using a waveguide with a memory effect, a photodiode, CMOS circuits and LEDs was proposed. To realize the neural network, optical waveguides with a memory effect were fabricated using a cladding layer containing the photochromic material “diarylethene”. The transmittance of green light was decreased by UV light irradiation and recovered by the passage of green light through the waveguide. It was confirmed that the transmittance versus total energy of the green light that passed through the waveguide well fit the universal exponential curve.

  2. Thermo-optic coefficient and nonlinear refractive index of silicon oxynitride waveguides

    NASA Astrophysics Data System (ADS)

    Trenti, A.; Borghi, M.; Biasi, S.; Ghulinyan, M.; Ramiro-Manzano, F.; Pucker, G.; Pavesi, L.

    2018-02-01

    Integrated waveguiding devices based on silicon oxynitride (SiON) are appealing for their relatively high refractive index contrast and broadband transparency. The lack of two photon absorption at telecom wavelengths and the possibility to fabricate low loss waveguides make SiON an ideal platform for on-chip nonlinear optics and for the realization of reconfigurable integrated quantum lightwave circuits. Despite this, very few studies on its linear and nonlinear optical properties have been reported so far. In this work, we measured the thermo-optic coefficient dn/dT and the nonlinear refractive index n2 of relatively high (n ˜ 1.83 at a wavelength of 1.55 μm) refractive index SiON by using racetrack resonators. These parameters have been determined to be d/n d T =(1.84 ±0.17 ) × 10-5 K-1 and n2 = (7 ± 1) × 10-16 cm2W-1.

  3. A reagentless enzymatic fluorescent biosensor for glucose based on upconverting glasses, as excitation source, and chemically modified glucose oxidase.

    PubMed

    Del Barrio, Melisa; Cases, Rafael; Cebolla, Vicente; Hirsch, Thomas; de Marcos, Susana; Wilhelm, Stefan; Galbán, Javier

    2016-11-01

    Upon near-infrared excitation Tm(3+)+Yb(3+) doped fluorohafnate glasses present upconversion properties and emit visible light. This property permits to use these glasses (UCG) as excitation sources for fluorescent optical biosensors. Taking this into account, in this work a fluorescent biosensor for glucose determination is designed and evaluated. The biosensor combines the UCG and the fluorescence of the enzyme glucose oxidase chemically modified with a fluorescein derivative (GOx-FS), whose intensity is modified during the enzymatic reaction with glucose. Optical parameters have been optimized and a mathematical model describing the behavior of the analytical signal is suggested. Working in FIA mode, the biosensor responds to glucose concentrations up to, at least, 15mM with a limit of detection of 1.9mM. The biosensor has a minimum lifetime of 9 days and has been applied to glucose determination in drinks. The applicability of the sensor was tested by glucose determination in two fruit juices. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Femtosecond writing of near-surface waveguides in lithium niobate for low-loss electro-optical modulators of broadband emission

    NASA Astrophysics Data System (ADS)

    Bukharin, Mikhail A.; Skryabin, Nikolay N.; Khudyakov, Dmitriy V.; Vartapetov, Sergey K.

    2016-05-01

    In the investigation we demonstrated technique of direct femtosecond laser writing of tracks with induced refractive index at record low depth under surface of lithium niobate (3-15 μm). It was shown that with the help of proposed technique one can be written claddings of near surface optical waveguides that plays a key role in fabrication of fast electro-optical modulators with low operating voltage. Fundamental problem resolved in the investigation consists in suppression of negative factors impeding femtosecond inscription of waveguides at low depths. To prevent optical breakdown of crystal surface we used high numerical aperture objectives for focusing of light. It was shown, that advanced heat accumulation regime of femtosecond inscription is inapplicable for writing of near-surface waveguides, and near the surface waveguides should be written in non-thermal regime in contrast to widespread femtosecond writing at depths of tens micrometers. Inscribed waveguides were examined for optical losses and polarization properties. It was experimentally shown, that femtosecond written near surface waveguides have such advantages over widely used proton exchanged and Ti-diffusion waveguides as lower optical losses (down to 0.3 dB/cm) and maintaining of all polarization states of propagation light, which is crucial for development of electro-optical modulators for broadband and ultrashort laser emission. Novelty of the results consists in technique of femtosecond inscription of waveguides at record low depths under the surface of crystals. As compared to previous investigations in the field (structures at depths near 50 um with buried electrodes), the obtained waveguides could be used with simple closely adjacent on-surface electrodes.

  5. Immunodetection of salivary biomarkers by an optical microfluidic biosensor with polyethylenimine-modified polythiophene-C70 organic photodetectors.

    PubMed

    Dong, Tao; Pires, Nuno Miguel Matos

    2017-08-15

    This work reports a novel optical microfluidic biosensor with highly sensitive organic photodetectors (OPDs) for absorbance-based detection of salivary protein biomarkers at the point of care. The compact and miniaturized biosensor has comprised OPDs made of polythiophene-C 70 bulk heterojunction for the photoactive layer; whilst a calcium-free cathode interfacial layer, made of linear polyethylenimine, was incorporated to the photodetectors to enhance the low cost. The OPDs realized onto a glass chip were aligned to antibody-functionalized chambers of a poly(methyl methacrylate) microfluidic chip, in where immunogold-silver assays were conducted. The biosensor has detected IL-8, IL-1β and MMP-8 protein in spiked saliva with high detection specificity and short analysis time exhibiting detection limits between 80pgmL -1 and 120pgmL -1 . The result for IL-8 was below the clinical established cut-off of 600pgmL -1 , which revealed the potential of the biosensor to early detection of oral cancer. The detection limit was also comparable to other previously reported immunosensors performed with bulky instrumentation or using inorganic photodetectors. The optical detection sensitivity of the polythiophene-C 70 OPD was enhanced by optimizing the thickness of the photoactive layer and anode interfacial layer prior to the saliva immunoassays. Further, the biosensor was tested with unspiked human saliva samples, and the results of measuring IL-8 and IL-1β were in statistical agreement with those provided by two commercial assays of ELISA. The optical microfluidic biosensor reported hereby offers an attractive and cost-effective tool to diagnostics or screening purposes at the point of care. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Azo biphenyl polyurethane: Preparation, characterization and application for optical waveguide switch

    NASA Astrophysics Data System (ADS)

    Jiang, Yan; Da, Zulin; Qiu, Fengxian; Yang, Dongya; Guan, Yijun; Cao, Guorong

    2018-01-01

    Azo waveguide polymers are of particular interest in the design of materials for applications in optical switch. The aim of this contribution was the synthesis and thermo-optic waveguide switch properties of azo biphenyl polyurethanes. A series of monomers and azo biphenyl polyurethanes (Azo BPU1 and Azo BPU2) were synthesized and characterized by FT-IR, UV-Vis spectroscopy and 1H NMR. The physical and mechanical properties of thin polymer films were measured. The refractive index and thermo-optic coefficient (dn/dT) of polymer films were investigated for TE (transversal electric) polarizations by ATR technique. The transmission loss of film was measured using the Charge Coupled Device digital imaging devices. The results showed the Azo BPU2 containing chiral azobenzene chromophore had higher dn/dT and lower transmission loss. Subsequently, a 1 × 2 Y-branch and 2 × 2 Mach-Zehnder optical switches based on the prepared polymers were designed and simulated. The results showed that the power consumption of all switches was less than 1.0 mW. Compared with 1 × 2 Y-branch optical switch, the 2 × 2 Mach-Zehnder optical switches based on the same polymer have the faster response time, which were about only 1.2 and 2.0 ms, respectively.

  7. Fiber optic choline biosensor

    NASA Astrophysics Data System (ADS)

    Wang, Hong; Cao, Xiaojian; Jia, Ke; Chai, Xueting; Lu, Hua; Lu, Zuhong

    2001-10-01

    A fiber optic fluorescence biosensor for choline is introduced in this paper. Choline is an important neurotransmitter in mammals. Due to the growing needs for on-site clinical monitoring of the choline, much effect has been devoted to develop choline biosensors. Fiber-optic fluorescence biosensors have many advantages, including miniaturization, flexibility, and lack of electrical contact and interference. The choline fiber-optic biosensor we designed implemented a bifurcated fiber to perform fluorescence measurements. The light of the blue LED is coupled into one end of the fiber as excitation and the emission spectrum from sensing film is monitored by fiber-spectrometer (S2000, Ocean Optics) through the other end of the fiber. The sensing end of the fiber is coated with Nafion film dispersed with choline oxidase and oxygen sensitive luminescent Ru(II) complex (Tris(2,2'-bipyridyl)dichlororuthenium(II), hexahydrate). Choline oxidase catalyzes the oxidation of choline to betaine and hydrogen peroxide while consuming oxygen. The fluorescence intensity of oxygen- sensitive Ru(II) are related to the choline concentration. The response of the fiber-optic sensor in choline solution is represented and discussed. The result indicates a low-cost, high-performance, portable choline biosensor.

  8. A novel optical waveguide LP01/LP02 mode converter

    NASA Astrophysics Data System (ADS)

    Shen, Dongya; Wang, Changhui; Ma, Chuan; Mellah, Hakim; Zhang, Xiupu; Yuan, Hong; Ren, Wenping

    2018-07-01

    A novel optical waveguide LP01 /LP02 mode converter is proposed using combination of bicone structure based on the coupled-mode theory. It is composed of a cladding, a tapered core and combined bicone structure. It is found that this mode converter can have operating bandwidth of 1350-1700 nm, i.e. 350 nm, with a conversion efficiency of ∼90% (∼0.5 dB) and low crosstalk from other modes

  9. Optical ridge waveguides preserving the thermo-optic features in LiNbO3 crystals fabricated by combination of proton implantation and selective wet etching.

    PubMed

    Tan, Yang; Chen, Feng

    2010-05-24

    We report on a new, simple method to fabricate optical ridge waveguides in a z-cut LiNbO3 wafer by using proton implantation and selective wet etching. The measured modal field is well confined in the ridge waveguide region, which is also confirmed by the numerical simulation. With thermal annealing treatment at 400 degrees C, the propagation loss of the ridge waveguides is determined to be as low as approximately 0.9 dB/cm. In addition, the measured thermo-optic coefficients of the waveguides are in good agreement with those of the bulk, suggesting potential applications in integrated photonics.

  10. Continuously tunable optical buffer with a dual silicon waveguide design.

    PubMed

    Horak, Peter; Stewart, Will; Loh, Wei H

    2011-06-20

    We propose a design for an optical buffer that comprises two coupled silicon waveguides, which is capable of generating a large continuously tunable change in the propagation delay time. The optical delay can be varied by more than 100% through varying the spacing between the waveguides.

  11. Planar optical waveguides for optical panel having gradient refractive index core

    DOEpatents

    Veligdan, James T.

    2001-01-01

    An optical panel is disclosed. A plurality of stacked planar optical waveguides are used to guide light from an inlet face to an outlet face of an optical panel. Each of the optical waveguides comprises a planar sheet of core material having a central plane. The core material has an index of refraction which decreases as the distance from the central plane increases. The decrease in the index of refraction occurs gradually and continuously.

  12. Planar optical waveguides for optical panel having gradient refractive index core

    DOEpatents

    Veligdan, James T.

    2004-08-24

    An optical panel is disclosed. A plurality of stacked planar optical waveguides are used to guide light from an inlet face to an outlet face of an optical panel. Each of the optical waveguides comprises a planar sheet of core material having a central plane. The core material has an index of refraction which decreases as the distance from the central plane increases. The decrease in the index of refraction occurs gradually and continuously.

  13. Inverse design of near unity efficiency perfectly vertical grating couplers

    NASA Astrophysics Data System (ADS)

    Michaels, Andrew; Yablonovitch, Eli

    2018-02-01

    Efficient coupling between integrated optical waveguides and optical fibers is essential to the success of integrated photonics. While many solutions exist, perfectly vertical grating couplers which scatter light out of a waveguide in the direction normal to the waveguide's top surface are an ideal candidate due to their potential to reduce packaging complexity. Designing such couplers with high efficiency, however, has proven difficult. In this paper, we use electromagnetic inverse design techniques to optimize a high efficiency two-layer perfectly vertical silicon grating coupler. Our base design achieves a chip-to-fiber coupling efficiency of over 99% (-0.04 dB) at 1550 nm. Using this base design, we apply subsequent constrained optimizations to achieve vertical couplers with over 96% efficiency which are fabricable using a 65 nm process.

  14. Nanoscale devices based on plasmonic coaxial waveguide resonators

    NASA Astrophysics Data System (ADS)

    Mahigir, A.; Dastmalchi, P.; Shin, W.; Fan, S.; Veronis, G.

    2015-02-01

    Waveguide-resonator systems are particularly useful for the development of several integrated photonic devices, such as tunable filters, optical switches, channel drop filters, reflectors, and impedance matching elements. In this paper, we introduce nanoscale devices based on plasmonic coaxial waveguide resonators. In particular, we investigate threedimensional nanostructures consisting of plasmonic coaxial stub resonators side-coupled to a plasmonic coaxial waveguide. We use coaxial waveguides with square cross sections, which can be fabricated using lithography-based techniques. The waveguides are placed on top of a silicon substrate, and the space between inner and outer coaxial metals is filled with silica. We use silver as the metal. We investigate structures consisting of a single plasmonic coaxial resonator, which is terminated either in a short or an open circuit, side-coupled to a coaxial waveguide. We show that the incident waveguide mode is almost completely reflected on resonance, while far from the resonance the waveguide mode is almost completely transmitted. We also show that the properties of the waveguide systems can be accurately described using a single-mode scattering matrix theory. The transmission and reflection coefficients at waveguide junctions are either calculated using the concept of the characteristic impedance or are directly numerically extracted using full-wave three-dimensional finite-difference frequency-domain simulations.

  15. Incorporating an optical waveguide into a neural interface

    DOEpatents

    Tolosa, Vanessa; Delima, Terri L.; Felix, Sarah H.; Pannu, Satinderpall S.; Shah, Kedar G.; Sheth, Heeral; Tooker, Angela C.

    2016-11-08

    An optical waveguide integrated into a multielectrode array (MEA) neural interface includes a device body, at least one electrode in the device body, at least one electrically conducting lead coupled to the at least one electrode, at least one optical channel in the device body, and waveguide material in the at least one optical channel. The fabrication of a neural interface device includes the steps of providing a device body, providing at least one electrode in the device body, providing at least one electrically conducting lead coupled to the at least one electrode, providing at least one optical channel in the device body, and providing a waveguide material in the at least one optical channel.

  16. Fast and simultaneous monitoring of organic pollutants in a drinking water treatment plant by a multi-analyte biosensor followed by LC-MS validation.

    PubMed

    Rodriguez-Mozaz, Sara; de Alda, Maria J López; Barceló, Damià

    2006-04-15

    This work describes the application of an optical biosensor (RIver ANALyser, RIANA) to the simultaneous analysis of three relevant environmental organic pollutants, namely, the pesticides atrazine and isoproturon and the estrogen estrone, in real water samples. This biosensor is based on an indirect inhibition immunoassay which takes place at a chemically modified optical transducer chip. The spatially resolved modification of the transducer surface allows the simultaneous determination of selected target analytes by means of "total internal reflection fluorescence" (TIRF). The performance of the immunosensor method developed was evaluated against a well accepted traditional method based on solid-phase extraction followed by liquid chromatography-mass spectrometry (LC-MS). The chromatographic method was superior in terms of linearity, sensitivity and accuracy, and the biosensor method in terms of repeatability, speed, cost and automation. The application of both methods in parallel to determine the occurrence and removal of atrazine, isoproturon and estrone throughout the treatment process (sand filtration, ozonation, activated carbon filtration and chlorination) in a waterworks showed an overestimation of results in the case of the biosensor, which was partially attributed to matrix and cross-reactivity effects, in spite of the addition of ovalbumin to the sample to minimize matrix interferences. Based on the comparative performance of both techniques, the biosensor emerges as a suitable tool for fast, simple and automated screening of water pollutants without sample pretreatment. To the author's knowledge, this is the first description of the application of the biosensor RIANA in the multi-analyte configuration to the regular monitoring of pollutants in a waterworks.

  17. Optical XOR gate

    DOEpatents

    Vawter, G. Allen

    2013-11-12

    An optical XOR gate is formed as a photonic integrated circuit (PIC) from two sets of optical waveguide devices on a substrate, with each set of the optical waveguide devices including an electroabsorption modulator electrically connected in series with a waveguide photodetector. The optical XOR gate utilizes two digital optical inputs to generate an XOR function digital optical output. The optical XOR gate can be formed from III-V compound semiconductor layers which are epitaxially deposited on a III-V compound semiconductor substrate, and operates at a wavelength in the range of 0.8-2.0 .mu.m.

  18. Optical NOR gate

    DOEpatents

    Skogen, Erik J [Albuquerque, NM; Tauke-Pedretti, Anna [Albuquerque, NM

    2011-09-06

    An optical NOR gate is formed from two pair of optical waveguide devices on a substrate, with each pair of the optical waveguide devices consisting of an electroabsorption modulator electrically connected in series with a waveguide photodetector. The optical NOR gate utilizes two digital optical inputs and a continuous light input to provide a NOR function digital optical output. The optical NOR gate can be formed from III-V compound semiconductor layers which are epitaxially deposited on a III-V compound semiconductor substrate, and operates at a wavelength in the range of 0.8-2.0 .mu.m.

  19. Method and apparatus for use of III-nitride wide bandgap semiconductors in optical communications

    DOEpatents

    Hui, Rongqing [Lenexa, KS; Jiang, Hong-Xing [Manhattan, KS; Lin, Jing-Yu [Manhattan, KS

    2008-03-18

    The present disclosure relates to the use of III-nitride wide bandgap semiconductor materials for optical communications. In one embodiment, an optical device includes an optical waveguide device fabricated using a III-nitride semiconductor material. The III-nitride semiconductor material provides for an electrically controllable refractive index. The optical waveguide device provides for high speed optical communications in an infrared wavelength region. In one embodiment, an optical amplifier is provided using optical coatings at the facet ends of a waveguide formed of erbium-doped III-nitride semiconductor materials.

  20. High efficiency all-optical plasmonic diode based on a nonlinear side-coupled waveguide-cavity structure with broken symmetry

    NASA Astrophysics Data System (ADS)

    Liang, Hong-Qin; Liu, Bin; Hu, Jin-Feng; He, Xing-Dao

    2018-05-01

    An all-optical plasmonic diode, comprising a metal-insulator-metal waveguide coupled with a stub cavity, is proposed based on a nonlinear Fano structure. The key technique used is to break structural spatial symmetry by a simple reflector layer in the waveguide. The spatial asymmetry of the structure gives rise to the nonreciprocity of coupling efficiencies between the Fano cavity and waveguides on both sides of the reflector layer, leading to a nonreciprocal nonlinear response. Transmission properties and dynamic responses are numerically simulated and investigated by the nonlinear finite-difference time-domain method. In the proposed structure, high-efficiency nonreciprocal transmission can be achieved with a low power threshold and an ultrafast response time (subpicosecond level). A high maximum transmittance of 89.3% and an ultra-high transmission contrast ratio of 99.6% can also be obtained. The device can be flexibly adjusted for working wavebands by altering the stub cavity length.

  1. The hybrid photonic planar integrated receiver with a polymer optical waveguide

    NASA Astrophysics Data System (ADS)

    Busek, Karel; Jerábek, Vitezslav; Armas Arciniega, Julio; Prajzler, Václav

    2008-11-01

    This article describes design of the photonic receiver composed of the system polymer planar waveguides, InGaAs p-i-n photodiode and integrated HBT amplifier on a low loss composite substrate. The photonic receiver was the main part of the hybrid integrated microwave optoelectronic transceiver TRx (transciever TRx) for the optical networks PON (passive optical networks) with FTTH (fiber-to-the-home) topology. In this article are presented the research results of threedimensional field between output facet of a optical waveguide and p-i-n photodiode. In terms of our research, there was optimized the optical coupling among the facet waveguide and pi-n photodiode and the electrical coupling among p-i-n photodiode and input of HBT amplifier. The hybrid planar lightwave circuit (PLC) of the transceiver TRx will be composed from a two parts - polymer optical waveguide including VHGT filter section and a optoelectronic microwave section.

  2. Optical waveguide circuit board with a surface-mounted optical receiver array

    NASA Astrophysics Data System (ADS)

    Thomson, J. E.; Levesque, Harold; Savov, Emil; Horwitz, Fred; Booth, Bruce L.; Marchegiano, Joseph E.

    1994-03-01

    A photonic circuit board is fabricated for potential application to interchip and interboard parallel optical links. The board comprises photolithographically patterned polymer optical waveguides on a conventional glass-epoxy electrical circuit board and a surface-mounted integrated circuit (IC) package that optically and electrically couples to an optoelectronic IC. The waveguide circuits include eight-channel arrays of straights, cross-throughs, curves, self- aligning interconnects to multi-fiber ribbon, and out-of-plane turning mirrors. A coherent, fused bundle of optical fibers couples light between 45-deg waveguide mirrors and a GaAs receiver array in the IC package. The fiber bundle is easily aligned to the mirrors and the receivers and is amenable to surface mounting and hermetic sealing. The waveguide-receiver- array board achieved error-free data rates up to 1.25 Gbits/s per channel, and modal noise was shown to be negligible.

  3. Graphene-based biosensors.

    PubMed

    Szunerits, Sabine; Boukherroub, Rabah

    2018-06-06

    Reliable data obtained from analysis of DNA, proteins, bacteria and other disease-related molecules or organisms in biological samples have become a fundamental and crucial part of human health diagnostics and therapy. The development of non-invasive tests that are rapid, sensitive, specific and simple would allow patient discomfort to be prevented, delays in diagnosis to be avoided and the status of a disease to be followed up. Bioanalysis is thus a progressive discipline for which the future holds many exciting opportunities. The use of biosensors for the early diagnosis of diseases has become widely accepted as a point-of-care diagnosis with appropriate specificity in a short time. To allow a reliable diagnosis of a disease at an early stage, highly sensitive biosensors are required as the corresponding biomarkers are generally expressed at very low concentrations. In the past 50 years, various biosensors have been researched and developed encompassing a wide range of applications. This contrasts the limited number of commercially available biosensors. When it comes to sensing of biomarkers with the required picomolar (pM) sensitivity for real-time sensing of biological samples, only a handful of sensing systems have been proposed, and these are often rather complex and costly. Lately, graphene-based materials have been considered as superior over other nanomaterials for the development of sensitive biosensors. The advantages of graphene-based sensor interfaces are numerous, including enhanced surface loading of the desired ligand due to the high surface-to-volume ratio, excellent conductivity and a small band gap that is beneficial for sensitive electrical and electrochemical read-outs, as well as tunable optical properties for optical read-outs such as fluorescence and plasmonics. In this paper, we review the advances made in recent years on graphene-based biosensors in the field of medical diagnosis.

  4. Efficient active waveguiding properties of Mo6 nano-cluster-doped polymer nanotubes

    NASA Astrophysics Data System (ADS)

    Bigeon, J.; Huby, N.; Amela-Cortes, M.; Molard, Y.; Garreau, A.; Cordier, S.; Bêche, B.; Duvail, J.-L.

    2016-06-01

    We investigate 1D nanostructures based on a Mo6@SU8 hybrid nanocomposite in which photoluminescent Mo6 clusters are embedded in the photosensitive SU8 resist. Tens of micrometers long Mo6@SU8-based tubular nanostructures were fabricated by the wetting template method, enabling the control of the inner and outer diameter to about 190 nm and 240 nm respectively, as supported by structural and optical characterizations. The image plane optical study of these nanotubes under optical pumping highlights the efficient waveguiding phenomenon of the red luminescence emitted by the clusters. Moreover, the wave vector distribution in the Fourier plane determined by leakage radiation microscopy gives additional features of the emission and waveguiding. First, the anisotropic red luminescence of the whole system can be attributed to the guided mode along the nanotube. Then, a low-loss propagation behavior is evidenced in the Mo6@SU8-based nanotubes. This result contrasts with the weaker waveguiding signature in the case of UV210-based nanotubes embedding PFO (poly(9,9-di-n-octylfluorenyl-2,7-diyl)). It is attributed to the strong reabsorption phenomenon, owing to overlapping between absorption and emission bands in the semi-conducting conjugated polymer PFO. These results make this Mo6@SU8 original class of nanocomposite a promising candidate as nanosources for submicronic photonic integration.

  5. Efficient active waveguiding properties of Mo6 nano-cluster-doped polymer nanotubes.

    PubMed

    Bigeon, J; Huby, N; Amela-Cortes, M; Molard, Y; Garreau, A; Cordier, S; Bêche, B; Duvail, J-L

    2016-06-24

    We investigate 1D nanostructures based on a Mo6@SU8 hybrid nanocomposite in which photoluminescent Mo6 clusters are embedded in the photosensitive SU8 resist. Tens of micrometers long Mo6@SU8-based tubular nanostructures were fabricated by the wetting template method, enabling the control of the inner and outer diameter to about 190 nm and 240 nm respectively, as supported by structural and optical characterizations. The image plane optical study of these nanotubes under optical pumping highlights the efficient waveguiding phenomenon of the red luminescence emitted by the clusters. Moreover, the wave vector distribution in the Fourier plane determined by leakage radiation microscopy gives additional features of the emission and waveguiding. First, the anisotropic red luminescence of the whole system can be attributed to the guided mode along the nanotube. Then, a low-loss propagation behavior is evidenced in the Mo6@SU8-based nanotubes. This result contrasts with the weaker waveguiding signature in the case of UV210-based nanotubes embedding PFO (poly(9,9-di-n-octylfluorenyl-2,7-diyl)). It is attributed to the strong reabsorption phenomenon, owing to overlapping between absorption and emission bands in the semi-conducting conjugated polymer PFO. These results make this Mo6@SU8 original class of nanocomposite a promising candidate as nanosources for submicronic photonic integration.

  6. Metal-capped silicon organic micro-ring electro-optical modulator (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Zaki, Aya O.; Kirah, Khaled A.; Swillam, Mohamed A.

    2017-02-01

    An ultra-compact hybrid plasmonic waveguide ring electro-optical modulator is designed to be easily fabricated on silicon on insulator (SOI) substrates using standard silicon photonics technology. The proposed waveguide is based on a buried standard silicon waveguide of height 220 nm topped with polymer and metal. The key advantage of this novel design is that only the silicon layer of the waveguide is structured as a coupled ring resonator. Then, the device is covered with electro-optical polymer and metal in post processes with no need for lithography or accurate mask alignment techniques. The simple fabrication method imposes many design challenges to obtain a resonator of reasonable loaded quality factor and high extinction ratio. Here, the performance of the resonator is optimized in the telecom wavelength range around 1550 nm using 3D FDTD simulations. The design of the coupling junction between the access waveguide and the tightly bent ring is thoroughly studied. The extension of the metal over the coupling region is exploited to make the critical dimension of the design geometry at least 2.5 times larger than conventional plasmonic resonators and the design is thus more robust. In this paper, we demonstrate an electro-optical modulator that offers an insertion loss < 1 dB, a modulation depth of 12 dB for an applied peak to peak voltage of only 2 V and energy consumption of 1.74 fJ/bit. The performance is superior to previously reported hybrid plasmonic ring resonator based modulators while the design shows robustness and low fabrication cost.

  7. Integrated-Optic Wavelength Multiplexer In Glass Fabricated By A Charge Controlled Ion Exchange

    NASA Astrophysics Data System (ADS)

    Klein, R.; Jestel, D.; Lilienhof, H. J.; Rottman, F.; Voges, E.

    1989-02-01

    Integrated-optic wavelength division multiplexing (WDM) is commonly used in communication systems. These WDM-devices are also well suited to build up optical fiber networks for both intensity and interferometric sensor types. The operation principle of our wavelength division multiplexing devise is based on the wavelength dependent two-mode interference in a two-moded waveguide, which is coupled adiabatically to the single-mode input and output strip waveguides. The single-mode input and output waveguides are connected via two Y-branches ( "'kJ- 1° branching angle ) with a two-moded intersection region. The ratio of the light powers in the single-mode output waveguides depends on wavelength . The two-mode interference within the two-moded center waveguide leads to an almost wavelength periodic transmission caracteristic . Dual-channel multiplexers/demultiplexers were fabricated by a charge controlled field assisted pottasium exchange in B-270 glass (Desag). The devices have a typical channel separation of 30 - 40 nm and a far-end crosstalk attenuation of better than 16 dB. The operation wavelength regions of the fabricated devices are 0.6 - 0.8 µm and 1.3 - 1.6 µm, respectively.

  8. Numerical model of the polymer electro-optic waveguide

    NASA Astrophysics Data System (ADS)

    Fan, Guofang; Li, Yuan; Han, Bing; Wang, Qi; Liu, Xinhou; Zhen, Zhen

    2012-09-01

    A numerical design model is presented for the polymer waveguide in an electro-optic modulator. The effective index method is used to analyze the height of the core waveguide and rib waveguide, an improved Marcatili method is presented to design the rib waveguide width in order to keep the strong single mode operation and have a good match with the standard fiber. Also, the thickness of the upper cladding layer is discussed through calculating the effective index of the multilayer planar waveguide structure has been obtained by setting the optical loss due to the metallic absorption to an acceptable value (<0.1 dB/cm). As a consequence, we take the EO polymer waveguide structure of UV15:CLD/APC:UFC170 as an example, an optimized design is reported.

  9. Traveling-wave photodetector

    DOEpatents

    Hietala, V.M.; Vawter, G.A.

    1993-12-14

    The traveling-wave photodetector of the present invention combines an absorptive optical waveguide and an electrical transmission line, in which optical absorption in the waveguide results in a photocurrent at the electrodes of the electrical transmission line. The optical waveguide and electrical transmission line of the electrically distributed traveling-wave photodetector are designed to achieve matched velocities between the light in the optical waveguide and electrical signal generated on the transmission line. This velocity synchronization provides the traveling-wave photodetector with a large electrical bandwidth and a high quantum efficiency, because of the effective extended volume for optical absorption. The traveling-wave photodetector also provides large power dissipation, because of its large physical size. 4 figures.

  10. Traveling-wave photodetector

    DOEpatents

    Hietala, Vincent M.; Vawter, Gregory A.

    1993-01-01

    The traveling-wave photodetector of the present invention combines an absorptive optical waveguide and an electrical transmission line, in which optical absorption in the waveguide results in a photocurrent at the electrodes of the electrical transmission line. The optical waveguide and electrical transmission line of the electrically distributed traveling-wave photodetector are designed to achieve matched velocities between the light in the optical waveguide and electrical signal generated on the transmission line. This velocity synchronization provides the traveling-wave photodetector with a large electrical bandwidth and a high quantum efficiency, because of the effective extended volume for optical absorption. The traveling-wave photodetector also provides large power dissipation, because of its large physical size.

  11. Optical properties of new wide heterogeneous waveguides with thermo optical shifters.

    PubMed

    De Leonardis, Francesco; Tsarev, Andrei V; Passaro, Vittorio M

    2008-12-22

    We present analysis and simulation of novel silicon-on-insulator (SOI) heterogeneous waveguides with thermo-optic phase shifters. New structure design contains a p-n junction on both sides of SOI ridge waveguide with 220 nm x 35 microm silicon core. Strongly mode-dependent optical losses (by additional free charge absorption) provide quasi-singe-mode behavior of wide waveguide with mode size approximately 10 microm. Local heater produces an efficient phase shifting by small temperature increase (DeltaT approximately 2K), switching power (< 40 mW) and switching time (< 10 micros). Mode optical losses are significantly decreased at high heating (DeltaT approximately 120 K).

  12. Ultrafast modulators based on nonlinear photonic crystal waveguides

    NASA Astrophysics Data System (ADS)

    Liu, Zhifu; Li, Jianheng; Tu, Yongming; Ho, Seng-Tiong; Wessels, Bruce W.

    2011-03-01

    Nonlinear photonic crystal (PhC) waveguides are being developed for ultrafast modulators. To enable phase velocity matching we have investigated one- and two-dimensional structures. Photonic crystal (PhC) waveguides based on epitaxial barium titanate (BTO) thin film in a Si3N4/BTO/MgO multilayer structure were fabricated by electron beam lithography or focused ion beam (FIB) milling. For both one- and two-dimensional PhCs, simulation shows that sufficient refractive index contrast is achieved to form a stop band. For one-dimensional Bragg reflector, we measured its slow light properties and the group refractive index of optical wave. For a millimeter long waveguide a 27 nm wide stop band was obtained at 1550 nm. A slowing of the light was observed, the group refractive indices at the mid band gap and at the band edges were estimated to be between 8.0 and 12 for the transverse electric (TE) mode, and 6.9 and 13 for the transverse magnetic (TM) mode. For TE optical modes, the enhancement factor of EO coefficient ranges from 7 to 13, and for the TM mode, the factor ranges from 5.9 to 15. Measurements indicate that near velocity phase matching can be realized. Upon realizing the phase velocity matching condition, devices with a small foot print with bandwidths at 490 GHz can be attained. Two-dimensional PhC crystal with a hexagonal lattice was also investigated. The PhCs were fabricated from epitaxial BTO thin film multilayers using focused ion beam milling. The PhCs are based on BTO slab waveguide and air hole arrays defined within Si3N4 and BTO thin films. A refractive index contrast of 0.4 between the barium titanate thin film multilayers and the air holes enables strong light confinement. For the TE optical mode, the hexagonal photonic crystal lattice with a diameter of 155 nm and a lattice constant of 740 nm yields a photonic bandgap over the wavelength range from 1525 to 1575 nm. The transmission spectrum of the PhC waveguide exhibits stronger Fabry Perot resonance compared to that of conventional waveguide. Measured transmission spectra show a bandgap in the ΓM direction in the reciprocal lattice that is in agreement with the simulated results using the finite-difference time-domain (FDTD) method. Compared to polarization intensity EO modulator with a half-wave voltage length product of 4.7 V•mm. The PhC based EO modulator has a factor of 6.6 improvement in the figure of merit performance. The thin film PhC waveguide devices show considerable potential for ultra-wide bandwidth electro-optic modulators as well as tunable optical filters and switches.

  13. Efficient Fluorescence Resonance Energy Transfer between Quantum Dots and Gold Nanoparticles Based on Porous Silicon Photonic Crystal for DNA Detection

    PubMed Central

    Zhang, Hongyan; Lv, Jie; Jia, Zhenhong

    2017-01-01

    A novel assembled biosensor was prepared for detecting 16S rRNA, a small-size persistent specific for Actinobacteria. The mechanism of the porous silicon (PS) photonic crystal biosensor is based on the fluorescence resonance energy transfer (FRET) between quantum dots (QDs) and gold nanoparticles (AuNPs) through DNA hybridization, where QDs act as an emission donor and AuNPs serve as a fluorescence quencher. Results showed that the photoluminescence (PL) intensity of PS photonic crystal was drastically increased when the QDs-conjugated probe DNA was adhered to the PS layer by surface modification using a standard cross-link chemistry method. The PL intensity of QDs was decreased when the addition of AuNPs-conjugated complementary 16S rRNA was dropped onto QDs-conjugated PS. Based on the analysis of different target DNA concentration, it was found that the decrease of the PL intensity showed a good linear relationship with complementary DNA concentration in a range from 0.25 to 10 μM, and the detection limit was 328.7 nM. Such an optical FRET biosensor functions on PS-based photonic crystal for DNA detection that differs from the traditional FRET, which is used only in liquid. This method will benefit the development of a new optical FRET label-free biosensor on Si substrate and has great potential in biochips based on integrated optical devices. PMID:28489033

  14. Rare-earth doped polymer waveguides and light emitting diodes

    NASA Astrophysics Data System (ADS)

    Slooff, L. H.

    2000-11-01

    Polymer-based optical waveguide amplifiers offer a low-cost alternative for inorganic waveguide amplifiers. Due to the fact that their refractive index is almost similar to that of standard optical fibers, they can be easily coupled with existing fibers at low coupling losses. Doping the polymer with rare-earth ions that can yield optical gain is not straightforward, as the rare-earth salts are poorly soluble in the polymer matrix. This thesis studies two different approaches to dope a polymer waveguide with rare-earth ions. The first one is based on organic cage-like complexes that encapsulate the rare-earth ion and are designed to provide enough coordination sites to bind the rare-earth ion and to shield it from the surrounding matrix. Chapter 2 describes the optical properties of Er-doped organic polydentate cage complexes. The complexes show clear photoluminescence at 1.54 mm with a bandwidth of 70 nm, the highest reported for an erbium-doped material so far. The luminescence lifetime is very short (~1 ms) due to coupling to vibrational overtones of O-H and C-H bonds. Due to this short luminescence lifetime, high pump powers (~1 W) are needed for optical gain in a waveguide amplifier based on these complexes. The pump power can be reduced if the Er is excited via the aromatic part of the complex, which has a higher absorption cross section. In Chapter 3 a lissamine-functionalised neodymium complex is studied in which the highly absorbing lissamine acts as a sensitiser. The lissamine is first excited into the singlet state from which intersystem crossing to the triplet state can take place. From there it can transfer its energy to the Nd ion by a Dexter transfer mechanism. Room-temperature photoluminescence at 890, 1060, and 1340 nm from Nd is observed, together with luminescence from the lissamine sensitiser at 600 nm. Photodegradation of the lissamine sensitiser is observed, which is studied in more detail in Chapter 4. The observed change in time of the spectral shape of the lissamine luminescence can be explained by assuming that two types of complexes exist. One type in which energy transfer to the Nd3+ ion can take place, and one that is not coupled to Nd. The highly absorbing sensitiser makes the standard butt-end coupling of the pump light into a waveguide amplifier impractical. The pump power can be used more efficiently by using a novel coupled waveguide system as described in Chapter 5. This employs gradual evanescent field coupling between parallel pump and signal waveguides. An alternative approach to make a rare-earth doped polymer waveguide is by combining the excellent properties of SiO2 as a host for the rare-earth with the easy processing of polymers. The optical properties of Er-doped silica films made by an acid-catalysed sol-gel synthesis are reported in Chapter 6. The Er exhibits long luminescence lifetimes of 10-12 ms, which indicates that OH from the wet chemical synthesis is successfully removed during the vacuum anneal treatment. Using a base-catalysed sol-gel synthesis, silica colloidal spheres with diameters of 175 and 340 nm were grown. Chapter 7 describes the luminescence properties of the 340 nm spheres, implanted with Er up to concentrations of 1.0 at.%. The Er shows a very long luminescence lifetime of 17 ms, and the radiative lifetime is estimated to be 20-22 ms, indicating a high quantum efficiency. This long luminescence lifetime is partly due to the low local optical density of states (DOS) in the free standing silica colloids. Optical gain calculations are made for the colloid/polymer waveguide that predicts a net gain of 8.7 dB at a pump power of 30 mW, for a 15 cm long waveguide. Such a length can be rolled up on an area of 16 mm2. In Chapter 8, calculations of the DOS are described for thin films as well as the spherical colloids. By comparing the calculation with experimentally probed decay rates, radiative and non-radiative components in the decay of Er are determined. Besides optical pumping of planar waveguide amplifiers it would be interesting if electrical pumping could be achieved. As a first step in this direction Chapter 9 reports 890 nm electroluminescence from lissamine-functionalised Nd complexes in a polymer light emitting diode. It is shown that the lissamine sensitiser plays a crucial role in mediating the energy transfer from the conjugated polymer to the Nd3+ ion, via singlet-singlet and triplet-triplet energy transfer. Finally, Chapter 10 gives an overview of important device considerations for the fabrication of optically and electrically pumped polymer-based planar optical amplifiers based on the novel materials concepts described in this thesis.

  15. A preliminary design of the Ti:LiNbO3 optical channel waveguide

    NASA Astrophysics Data System (ADS)

    Choi, Yat

    1992-03-01

    One of the goals of technology-based activities within the Electronic Warfare Division is to facilitate the development within Australia, of facilities and a capability to manufacture sophisticated, highspeed electro-optic devices, in particular, the integrated optical amplitude modulator and integrated optical switch, for use in microwave and millimetre-wave systems for the Australian Defense Force (ADF). An initial step towards this goal would be to produce a low-loss and single-mode propagation optical channel waveguide using titanium-indiffused lithium niobate (Ti:LiNbO3). As no dimensions and fabrication parameters have yet been optimized, this technical report provides preliminary design data which optimizes these parameters.

  16. Nanoporous Anodic Alumina: A Versatile Platform for Optical Biosensors

    PubMed Central

    Santos, Abel; Kumeria, Tushar; Losic, Dusan

    2014-01-01

    Nanoporous anodic alumina (NAA) has become one of the most promising nanomaterials in optical biosensing as a result of its unique physical and chemical properties. Many studies have demonstrated the outstanding capabilities of NAA for developing optical biosensors in combination with different optical techniques. These results reveal that NAA is a promising alternative to other widely explored nanoporous platforms, such as porous silicon. This review is aimed at reporting on the recent advances and current stage of development of NAA-based optical biosensing devices. The different optical detection techniques, principles and concepts are described in detail along with relevant examples of optical biosensing devices using NAA sensing platforms. Furthermore, we summarise the performance of these devices and provide a future perspective on this promising research field. PMID:28788678

  17. Improved optical efficiency of bulk laser amplifiers with femtosecond written waveguides

    NASA Astrophysics Data System (ADS)

    Bukharin, Mikhail A.; Lyashedko, Andrey; Skryabin, Nikolay N.; Khudyakov, Dmitriy V.; Vartapetov, Sergey K.

    2016-04-01

    In the paper we proposed improved technique of three-dimensional waveguides writing with direct femtosecond laser inscription technology. The technique allows, for the first time of our knowledge, production of waveguides with mode field diameter larger than 200 μm. This result broadens field of application of femtosecond writing technology into bulk laser schemes and creates an opportunity to develop novel amplifiers with increased efficiency. We proposed a novel architecture of laser amplifier that combines free-space propagation of signal beam with low divergence and propagation of pump irradiation inside femtosecond written waveguide with large mode field diameter due to total internal reflection effect. Such scheme provides constant tight confinement of pump irradiation over the full length of active laser element (3-10 cm). The novel amplifier architecture was investigated numerically and experimentally in Nd:phosphate glass. Waveguides with 200 μm mode field diameter were written with high frequency femtosecond oscillator. Proposed technique of three-dimensional waveguides writing based on decreasing and compensation of spherical aberration effect due to writing in heat cumulative regime and dynamic pulse energy adjustment at different depths of writing. It was shown, that written waveguides could increase optical efficiency of amplifier up to 4 times compared with corresponding usual free-space schemes. Novelty of the results consists in technique of femtosecond writing of waveguides with large mode field diameter. Actuality of the results consists in originally proposed architecture allows to improve up to 4 times optical efficiency of conventional bulk laser schemes and especially ultrafast pulse laser amplifiers.

  18. Optofluidic waveguides: I. Concepts and implementations

    PubMed Central

    Schmidt, Holger; Hawkins, Aaron R.

    2011-01-01

    We review recent developments and current status of liquid-core optical waveguides in optofluidics with emphasis on suitability for creating fully planar optofluidic labs-on-a-chip. In this first of two contributions, we give an overview of the different waveguide types that are being considered for effectively combining micro and nanofluidics with integrated optics. The large number of approaches is separated into conventional index-guided waveguides and more recent implementations using wave interference. The underlying principle for waveguiding and the current status are described for each type. We then focus on reviewing recent work on microfabricated liquid-core antiresonant reflecting optical (ARROW) waveguides, including the development of intersecting 2D waveguide networks and optical fluorescence and Raman detection with planar beam geometry. Single molecule detection capability and addition of electrical control for electrokinetic manipulation and analysis of single bioparticles are demonstrated. The demonstrated performance of liquid-core ARROWs is representative of the potential of integrated waveguides for on-chip detection with ultrahigh sensitivity, and points the way towards the next generation of high-performance, low-cost and portable biomedical instruments. PMID:21442048

  19. Optical pulling force and conveyor belt effect in resonator-waveguide system.

    PubMed

    Intaraprasonk, Varat; Fan, Shanhui

    2013-09-01

    We present the theoretical condition and actual numerical design that achieves an optical pulling force in resonator-waveguide systems, where the direction of the force on the resonator is in the opposite direction to the input light in the waveguide. We also show that this pulling force can occur in conjunction with the lateral optical equilibrium effect, such that the resonator is maintained at the fixed distance from the waveguide while experiencing the pulling force.

  20. InGaAsP/InP optical waveguide switch operated by a carrier-induced change in the refractive index

    NASA Astrophysics Data System (ADS)

    Mikami, O.; Nakagome, H.

    1985-11-01

    Waveguided semiconductor optical switches operated by a carrier-induced change in the refractive-index associated with the plasma dispersion are proposed. InGaAsP/InP four-port switches having two intersecting single-mode channel waveguides are fabricated by selective liquid-phase epitaxy and investigated at 1.5 microns wavelength. Optical switching is observed as a result of mode interference in the waveguide intersection region.

  1. Characterization of passive polymer optical waveguides

    NASA Astrophysics Data System (ADS)

    Joehnck, Matthias; Kalveram, Stefan; Lehmacher, Stefan; Pompe, Guido; Rudolph, Stefan; Neyer, Andreas; Hofstraat, Johannes W.

    1999-05-01

    The characterization of monomode passive polymer optical devices fabricated according to the POPCORN technology by methods originated from electron, ion and optical spectroscopy is summarized. Impacts of observed waveguide perturbations on the optical characteristics of the waveguide are evaluated. In the POPCORN approach optical components for telecommunication applications are fabricated by photo-curing of liquid halogenated (meth)acrylates which have been applied on moulded thermoplastic substrates. For tuning of waveguide material refractive indices with respect to the substrate refractive index frequently comonomer mixtures are used. The polymerization characteristics, especially the polymerization kinetics of individual monomers, determine the formation of copolymers. Therefore the unsaturation as function of UV-illumination time in the formation of halogenated homo- and copolymers has been examined. From different suitable copolymer system, after characterization of their glass transition temperatures, their curing behavior and their refractive indices as function of the monomer ratios, monomode waveguides applying PMMA substrates have been fabricated. To examine the materials composition also in the 6 X 6 micrometers 2 waveguides they have been visualized by transmission electron microscopy. With this method e.g. segregation phenomena could be observed in the waveguide cross section characterization as well. The optical losses in monomode waveguides caused by segregation and other materials induce defects like micro bubbles formed as a result of shrinkage have been quantized by return loss measurements. Defects causing scattering could be observed by convocal laser scanning microscopy and by conventional light microscopy.

  2. Multisite silicon neural probes with integrated silicon nitride waveguides and gratings for optogenetic applications.

    PubMed

    Shim, Euijae; Chen, Yu; Masmanidis, Sotiris; Li, Mo

    2016-03-04

    Optimal optogenetic perturbation of brain circuit activity often requires light delivery in a precise spatial pattern that cannot be achieved with conventional optical fibers. We demonstrate an implantable silicon-based probe with a compact light delivery system, consisting of silicon nitride waveguides and grating couplers for out-of-plane light emission with high spatial resolution. 473 nm light is coupled into and guided in cm-long waveguide and emitted at the output grating coupler. Using the direct cut-back and out-scattering measurement techniques, the propagation optical loss of the waveguide is measured to be below 3 dB/cm. The grating couplers provide collimated light emission with sufficient irradiance for neural stimulation. Finally, a probe with multisite light delivery with three output grating emitters from a single laser input is demonstrated.

  3. INTEGRATED AND FIBER OPTICS: Threshold of photoinduced conversion of the polarization of radiation in lithium niobate optical waveguides

    NASA Astrophysics Data System (ADS)

    Kazanskiĭ, P. G.

    1989-02-01

    A threshold of photoinduced conversion of an ordinary wave into an extraordinary one was discovered for lithium niobate optical waveguides. The threshold intensity of the radiation was determined for waveguides prepared under different conditions. The experimental results were compared with theoretical estimates.

  4. Photo-induced reduction of graphene oxide coating on optical waveguide and consequent optical intermodulation

    PubMed Central

    Chong, W. Y.; Lim, W. H.; Yap, Y. K.; Lai, C. K.; De La Rue, R. M.; Ahmad, H.

    2016-01-01

    Increased absorption of transverse-magnetic (TM) - polarised light by a graphene-oxide (GO) coated polymer waveguide has been observed in the presence of transverse-electric (TE) - polarised light. The GO-coated waveguide exhibits very strong photo-absorption of TE-polarised light - and acts as a TM-pass waveguide polariser. The absorbed TE-polarised light causes a significant temperature increase in the GO film and induces thermal reduction of the GO, resulting in an increase in optical-frequency conductivity and consequently increased optical propagation loss. This behaviour in a GO-coated waveguide gives the action of an inverted optical switch/modulator. By varying the incident TE-polarised light power, a maximum modulation efficiency of 72% was measured, with application of an incident optical power level of 57 mW. The GO-coated waveguide was able to respond clearly to modulated TE-polarised light with a pulse duration of as little as 100 μs. In addition, no wavelength dependence was observed in the response of either the modulation (TE-polarised light) or the signal (TM-polarised light). PMID:27034015

  5. Strategies for leukemic biomarker detection using long-range surface plasmon-polaritons

    NASA Astrophysics Data System (ADS)

    Krupin, O.; Wang, C.; Berini, P.

    2014-09-01

    The suitability and use of long-range surface plasmon-polaritons for leukemic biomarker detection is discussed. A novel optical biosensor comprised of gold straight waveguides embedded in CYTOP with an etched microfluidic channel was tested for detecting leukemia in patient serum. Gold surface functionalization involved the interaction of protein G (PG) with antibodies by first adsorbing PG on bare gold and then antibodies (Immunoglobulin G, IgG). Differentiation between healthy and leukemia patients was based on the difference in ratios of Ig kappa (Igκ) and Ig lambda (Igλ) light chains in both serums. The ratio for a normal patient is ~1.4 - 2, whereas for a leukemia patient this ratio is altered. As a receptor (primary antibodies), goat anti-human anti-IgGκ and anti-IgGλ were used to functionalize the surface. Diluted normal and leukemia patient serums were tested over the aforementioned surfaces. The ratios of mass surface densities of IgGκ:IgGλ for normal serum (NS) and patient serum (PS) were found to be 1.55 and 1.92 respectively.

  6. Atto-Joule, high-speed, low-loss plasmonic modulator based on adiabatic coupled waveguides

    NASA Astrophysics Data System (ADS)

    Dalir, Hamed; Mokhtari-Koushyar, Farzad; Zand, Iman; Heidari, Elham; Xu, Xiaochuan; Pan, Zeyu; Sun, Shuai; Amin, Rubab; Sorger, Volker J.; Chen, Ray T.

    2018-05-01

    In atomic multi-level systems, adiabatic elimination (AE) is a method used to minimize complicity of the system by eliminating irrelevant and strongly coupled levels by detuning them from one another. Such a three-level system, for instance, can be mapped onto physically in the form of a three-waveguide system. Actively detuning the coupling strength between the respective waveguide modes allows modulating light to propagate through the device, as proposed here. The outer waveguides act as an effective two-photonic-mode system similar to ground and excited states of a three-level atomic system, while the center waveguide is partially plasmonic. In AE regime, the amplitude of the middle waveguide oscillates much faster when compared to the outer waveguides leading to a vanishing field build up. As a result, the plasmonic intermediate waveguide becomes a "dark state," hence nearly zero decibel insertion loss is expected with modulation depth (extinction ratio) exceeding 25 dB. Here, the modulation mechanism relies on switching this waveguide system from a critical coupling regime to AE condition via electrostatically tuning the free-carrier concentration and hence the optical index of a thin indium thin oxide (ITO) layer resides in the plasmonic center waveguide. This alters the effective coupling length and the phase mismatching condition thus modulating in each of its outer waveguides. Our results also promise a power consumption as low as 49.74aJ/bit. Besides, we expected a modulation speed of 160 GHz reaching to millimeter wave range applications. Such anticipated performance is a direct result of both the unity-strong tunability of the plasmonic optical mode in conjunction with utilizing ultra-sensitive modal coupling between the critically coupled and the AE regimes. When taken together, this new class of modulators paves the way for next generation both for energy and speed conscience optical short-reach communication such as those found in interconnects.

  7. Design issues for directional coupler- and MMI-based optical microring resonator filters on InP

    NASA Astrophysics Data System (ADS)

    Themistos, Christos; Kalli, Kyriacos; Komodromos, Michalis; Rajarajan, Muttukrishnan; Rahman, B. M. A.; Grattan, Kenneth T. V.

    2004-08-01

    The characterization and optimization of optical microring resonator-based optical filters on deeply etched GaInAsP-Inp waveguides, using the finite element-based beam propagation approach is presented here. Design issues for directional coupler- and multimode interference coupler-based devices, such as field evolution, optical power, phase, fabrication tolerance and wavelength dependence have been investigated.

  8. Merged beam laser design for reduction of gain-saturation and two-photon absorption in high power single mode semiconductor lasers.

    PubMed

    Lysevych, M; Tan, H H; Karouta, F; Fu, L; Jagadish, C

    2013-04-08

    In this paper we report a method to overcome the limitations of gain-saturation and two-photon absorption faced by developers of high power single mode InP-based lasers and semiconductor optical amplifiers (SOA) including those based on wide-waveguide or slab-coupled optical waveguide laser (SCOWL) technology. The method is based on Y-coupling design of the laser cavity. The reduction in gain-saturation and two-photon absorption in the merged beam laser structures (MBL) are obtained by reducing the intensity of electromagnetic field in the laser cavity. Standard ridge-waveguide lasers and MBLs were fabricated, tested and compared. Despite a slightly higher threshold current, the reduced gain-saturation in MBLs results in higher output power. The MBLs also produced a single spatial mode, as well as a strongly dominating single spectral mode which is the inherent feature of MBL-type cavity.

  9. [Research on symmetrical optical waveguide based surface plasmon resonance sensing with spectral interrogation].

    PubMed

    Zhang, Yi-long; Liu, Le; Guo, Jun; Zhang, Peng-fei; Guo, Ji-hua; Ma, Hui; He, Yong-hong

    2015-02-01

    Surface plasmon resonance (SPR) sensors with spectral interrogation can adopt fiber to transmit light signals, thus leaving the sensing part separated, which is very convenient for miniaturization, remote-sensing and on-site analysis. Symmetrical optical waveguide (SOW) SPR has the same refractive index of the-two buffer media layers adjacent to the metal film, resulting in longer propagation distance, deeper penetration depth and better performance compared to conventional SPR In the present paper, we developed a symmetrical optical, waveguide (SOW) SPR sensor with wavelength interrogation. In the system, MgF2-Au-MgF2 film was used as SOW module for glucose sensing, and a fiber based light source and detection was used in the spectral interrogation. In the experiment, a refractive index resolution of 2.8 x 10(-7) RIU in fluid protocol was acquired. This technique provides advantages of high resolution and could have potential use in compact design, on-site analysis and remote sensing.

  10. Liquid crystal waveguides: new devices enabled by >1000 waves of optical phase control

    NASA Astrophysics Data System (ADS)

    Davis, Scott R.; Farca, George; Rommel, Scott D.; Johnson, Seth; Anderson, Michael H.

    2010-02-01

    A new electro-optic waveguide platform, which provides unprecedented voltage control over optical phase delays (> 2mm), with very low loss (< 0.5 dB/cm) and rapid response time (sub millisecond), will be presented. This technology, developed by Vescent Photonics, is based upon a unique liquid-crystal waveguide geometry, which exploits the tremendous electro-optic response of liquid crystals while circumventing their historic limitations. The waveguide geometry provides nematic relaxation speeds in the 10's of microseconds and LC scattering losses that are reduced by orders of magnitude from bulk transmissive LC optics. The exceedingly large optical phase delays accessible with this technology enable the design and construction of a new class of previously unrealizable photonic devices. Examples include: 2-D analog non-mechanical beamsteerers, chip-scale widely tunable lasers, chip-scale Fourier transform spectrometer (< 5 nm resolution demonstrated), widely tunable micro-ring resonators, tunable lenses, ultra-low power (< 5 microWatts) optical switches, true optical time delay devices for phased array antennas, and many more. All of these devices may benefit from established manufacturing technologies and ultimately may be as inexpensive as a calculator display. Furthermore, this new integrated photonic architecture has applications in a wide array of commercial and defense markets including: remote sensing, micro-LADAR, OCT, FSO, laser illumination, phased array radar, etc. Performance attributes of several example devices and application data will be presented. In particular, we will present a non-mechanical beamsteerer that steers light in both the horizontal and vertical dimensions.

  11. A chip-integrated coherent photonic-phononic memory.

    PubMed

    Merklein, Moritz; Stiller, Birgit; Vu, Khu; Madden, Stephen J; Eggleton, Benjamin J

    2017-09-18

    Controlling and manipulating quanta of coherent acoustic vibrations-phonons-in integrated circuits has recently drawn a lot of attention, since phonons can function as unique links between radiofrequency and optical signals, allow access to quantum regimes and offer advanced signal processing capabilities. Recent approaches based on optomechanical resonators have achieved impressive quality factors allowing for storage of optical signals. However, so far these techniques have been limited in bandwidth and are incompatible with multi-wavelength operation. In this work, we experimentally demonstrate a coherent buffer in an integrated planar optical waveguide by transferring the optical information coherently to an acoustic hypersound wave. Optical information is extracted using the reverse process. These hypersound phonons have similar wavelengths as the optical photons but travel at five orders of magnitude lower velocity. We demonstrate the storage of phase and amplitude of optical information with gigahertz bandwidth and show operation at separate wavelengths with negligible cross-talk.Optical storage implementations based on optomechanical resonator are limited to one wavelength. Here, exploiting stimulated Brillouin scattering, the authors demonstrate a coherent optical memory based on a planar integrated waveguide, which can operate at different wavelengths without cross-talk.

  12. Investigation of semiconductor clad optical waveguides

    NASA Technical Reports Server (NTRS)

    Batchman, T. E.; Mcwright, G. M.

    1982-01-01

    Glass waveguides are studied because of the ease and economy of fabricating devices in glass. All calculations are based on the assumption of a glass guide and substrate, but the effects being studied will occur on other materials if the proper refractive indices are used in the calculations.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Zheng; Xu, Xiaochuan; Fan, Donglei

    Here, subwavelength grating (SWG) waveguide is an intriguing alternative to conventional optical waveguides due to the extra degree of freedom it offers in tuning a few important waveguide properties, such as dispersion and refractive index. Devices based on SWG waveguides have demonstrated impressive performances compared to conventional waveguides. However, the high loss of SWG waveguide bends jeopardizes their applications in integrated photonic circuits. In this work, we propose a geometrical tuning art, which realizes a pre-distorted refractive index profile in SWG waveguide bends. The pre-distorted refractive index profile can effectively reduce the mode mismatch and radiation loss simultaneously, thus significantlymore » reduce the bend loss. This geometry tuning art has been numerically optimized and experimentally demonstrated in present study. Through such tuning, the average insertion loss of a 5 μm SWG waveguide bend is reduced drastically from 5.43 dB to 1.10 dB per 90° bend for quasi-TE polarization. In the future, the proposed scheme will be utilized to enhance performance of a wide range of SWG waveguide based photonics devices.« less

  14. Temporal waveguides for optical pulses

    DOE PAGES

    Plansinis, Brent W.; Donaldson, William R.; Agrawal, Govind P.

    2016-05-12

    Here we discuss, temporal total internal reflection (TIR), in analogy to the conventional TIR of an optical beam at a dielectric interface, is the total reflection of an optical pulse inside a dispersive medium at a temporal boundary across which the refractive index changes. A pair of such boundaries separated in time acts as the temporal analog of planar dielectric waveguides. We study the propagation of optical pulses inside such temporal waveguides, both analytically and numerically, and show that the waveguide supports a finite number of temporal modes. We also discuss how a single-mode temporal waveguide can be created inmore » practice. In contrast with the spatial case, the confinement can occur even when the central region has a lower refractive index.« less

  15. WGM resonators for studying orbital angular momentum of a photon, and methods

    NASA Technical Reports Server (NTRS)

    Matsko, Andrey B. (Inventor); Savchenkov, Anatoliy A. (Inventor); Maleki, Lute (Inventor); Strekalov, Dmitry V. (Inventor)

    2009-01-01

    An optical system, device, and method that are capable of generating high-order Bessel beams and determining the orbital angular momentum of at least one of the photons of a Bessel beam are provided. The optical system and device include a tapered waveguide having an outer surface defined by a diameter that varies along a longitudinal axis of the waveguide from a first end to an opposing second end. The optical system and device include a resonator that is arranged in optical communication with the first end of the tapered waveguide such that an evanescent field emitted from (i) the waveguide can be coupled with the resonator, or (ii) the resonator can be coupled with the waveguide.

  16. DNA-Aptamer optical biosensors based on a LPG-SPR optical fiber platform for point-of-care diagnostic

    NASA Astrophysics Data System (ADS)

    Coelho, L.; Queirós, R. B.; Santos, J. L.; Martins, M. Cristina L.; Viegas, D.; Jorge, P. A. S.

    2014-03-01

    Surface Plasmon Resonance (SPR) is the base for some of the most sensitive label free optical fiber biosensors. However, most solutions presented to date require the use of fragile fiber optic structure such as adiabatic tapers or side polished fibers. On the other hand, long-period fiber gratings (LPG) present themselves as an interesting solution to attain an evanescent wave refractive index sensor platform while preserving the optical fiber integrity. The combination of these two approaches constitute a powerful platform that can potentially reach the highest sensitivities as it was recently demonstrated by detailed theoretical study [1, 2]. In this work, a LPG-SPR platform is explored in different configurations (metal coating between two LPG - symmetric and asymmetric) operating in the telecom band (around 1550 nm). For this purpose LPGs with period of 396 μm are combined with tailor made metallic thin films. In particular, the sensing regions were coated with 2 nm of chromium to improve the adhesion to the fiber and 16 nm of gold followed by a 100 nm thick layer of TiO2 dielectric material strategically chosen to attain plasmon resonance in the desired wavelength range. The obtained refractometric platforms were then validated as a biosensor. For this purpose the detection of thrombin using an aptamer based probe was used as a model system for protein detection. The surface of the sensing fibers were cleaned with isopropanol and dried with N2 and then the aminated thrombin aptamer (5'-[NH2]- GGTTGGTGTGGTTGG-3') was immobilized by physisorption using Poly-L-Lysine (PLL) as cationic polymer. Preliminary results indicate the viability of the LPFG-SPR-APTAMER as a flexible platforms point of care diagnostic biosensors.

  17. Periodically modulated single-photon transport in one-dimensional waveguide

    NASA Astrophysics Data System (ADS)

    Li, Xingmin; Wei, L. F.

    2018-03-01

    Single-photon transport along a one-dimension waveguide interacting with a quantum system (e.g., two-level atom) is a very useful and meaningful simplified model of the waveguide-based optical quantum devices. Thus, how to modulate the transport of the photons in the waveguide structures by adjusting certain external parameters should be particularly important. In this paper, we discuss how such a modulation could be implemented by periodically driving the energy splitting of the interacting atom and the atom-photon coupling strength. By generalizing the well developed time-independent full quantum mechanical theory in real space to the time-dependent one, we show that various sideband-transmission phenomena could be observed. This means that, with these modulations the photon has certain probabilities to transmit through the scattering atom in the other energy sidebands. Inversely, by controlling the sideband transmission the periodic modulations of the single photon waveguide devices could be designed for the future optical quantum information processing applications.

  18. Recent Advances on Luminescent Enhancement-Based Porous Silicon Biosensors.

    PubMed

    Jenie, S N Aisyiyah; Plush, Sally E; Voelcker, Nicolas H

    2016-10-01

    Luminescence-based detection paradigms have key advantages over other optical platforms such as absorbance, reflectance or interferometric based detection. However, autofluorescence, low quantum yield and lack of photostability of the fluorophore or emitting molecule are still performance-limiting factors. Recent research has shown the need for enhanced luminescence-based detection to overcome these drawbacks while at the same time improving the sensitivity, selectivity and reducing the detection limits of optical sensors and biosensors. Nanostructures have been reported to significantly improve the spectral properties of the emitting molecules. These structures offer unique electrical, optic and magnetic properties which may be used to tailor the surrounding electrical field of the emitter. Here, the main principles behind luminescence and luminescence enhancement-based detections are reviewed, with an emphasis on europium complexes as the emitting molecule. An overview of the optical porous silicon microcavity (pSiMC) as a biosensing platform and recent proof-of-concept examples on enhanced luminescence-based detection using pSiMCs are provided and discussed.

  19. Enhancement of coupling ratios in SOI based asymmetrical optical directional couplers

    NASA Astrophysics Data System (ADS)

    Pendam, Nagaraju; Vardhani, Chunduru Parvatha

    2017-11-01

    A novel design of slab structured asymmetrical optical directional coupler with S-bend waveguides on silicon-on-insulator (SOI) platform has been designed by using R-Soft CAD tool. Beam propagation method (BPM) is used for light propagation analysis. The simulation results of asymmetrical optical directional couplers are reported. We find that the asymmetrical directional coupler has lower coupling ratios and higher extinction ratios with waveguide parameters such as width, wavelength, waveguide spacing, and coupling length. Simulation results designate that the coupling efficiency for transverse electric (TE) and transverse magnetic (TM) modes can reach about more than 95% and extinction ratio about 6 dB when the coupling length is 6 mm for both the polarization modes and insertion loss is 17 dB with same coupling length 6 mm at central wavelength 1550 nm.

  20. Nanocrystal waveguide (NOW) laser

    DOEpatents

    Simpson, John T.; Simpson, Marcus L.; Withrow, Stephen P.; White, Clark W.; Jaiswal, Supriya L.

    2005-02-08

    A solid state laser includes an optical waveguide and a laser cavity including at least one subwavelength mirror disposed in or on the optical waveguide. A plurality of photoluminescent nanocrystals are disposed in the laser cavity. The reflective subwavelength mirror can be a pair of subwavelength resonant gratings (SWG), a pair of photonic crystal structures (PC), or a distributed feedback structure. In the case of a pair of mirrors, a PC which is substantially transmissive at an operating wavelength of the laser can be disposed in the laser cavity between the subwavelength mirrors to improve the mode structure, coherence and overall efficiency of the laser. A method for forming a solid state laser includes the steps of providing an optical waveguide, creating a laser cavity in the optical waveguide by disposing at least one subwavelength mirror on or in the waveguide, and positioning a plurality of photoluminescent nanocrystals in the laser cavity.

  1. Observation and investigation of narrow optical transitions of 167Er3+ ions in femtosecond laser printed waveguides in 7LiYF4 crystal

    NASA Astrophysics Data System (ADS)

    Minnegaliev, M. M.; Dyakonov, I. V.; Gerasimov, K. I.; Kalinkin, A. A.; Kulik, S. P.; Moiseev, S. A.; Saygin, M. Yu; Urmancheev, R. V.

    2018-04-01

    We produced optical waveguides in the 167Er3+:7 LiYF4 crystal with diameters ranging from 30 to 100 μm by using the depressed-cladding approach with femtosecond laser. Stationary and coherent spectroscopy was performed on the 809 nm optical transitions between the hyperfine sublevels of 4I15/2 and 4I9/2 multiplets of 167Er3+ ions both inside and outside of waveguides. It was found that the spectra of 167Er3+ were slightly broadened and shifted inside the waveguides compared to the bulk crystal spectra. We managed to observe a two-pulse photon echo on this transition and determined phase relaxation times for each waveguide. The experimental results show that the created crystal waveguides doped by rare-earth ions can be used in optical quantum memory and integrated quantum schemes.

  2. Low-index discontinuity terahertz waveguides

    NASA Astrophysics Data System (ADS)

    Nagel, Michael; Marchewka, Astrid; Kurz, Heinrich

    2006-10-01

    A new type of dielectric THz waveguide based on recent approaches in the field of integrated optics is presented with theoretical and experimental results. Although the guiding mechanism of the low-index discontinuity (LID) THz waveguide is total internal reflection, the THz wave is predominantly confined in the virtually lossless low-index air gap within a high-index dielectric waveguide due to the continuity of electric flux density at the dielectric interface. Attenuation, dispersion and single-mode confinement properties of two LID structures are discussed and compared with other THz waveguide solutions. The new approach provides an outstanding combination of high mode confinement and low transmission losses currently not realizable with any other metal-based or photonic crystal approach. These exceptional properties might enable the breakthrough of novel integrated THz systems or endoscopy applications with sub-wavelength resolution.

  3. Embedded optical interconnect technology in data storage systems

    NASA Astrophysics Data System (ADS)

    Pitwon, Richard C. A.; Hopkins, Ken; Milward, Dave; Muggeridge, Malcolm

    2010-05-01

    As both data storage interconnect speeds increase and form factors in hard disk drive technologies continue to shrink, the density of printed channels on the storage array midplane goes up. The dominant interconnect protocol on storage array midplanes is expected to increase to 12 Gb/s by 2012 thereby exacerbating the performance bottleneck in future digital data storage systems. The design challenges inherent to modern data storage systems are discussed and an embedded optical infrastructure proposed to mitigate this bottleneck. The proposed solution is based on the deployment of an electro-optical printed circuit board and active interconnect technology. The connection architecture adopted would allow for electronic line cards with active optical edge connectors to be plugged into and unplugged from a passive electro-optical midplane with embedded polymeric waveguides. A demonstration platform has been developed to assess the viability of embedded electro-optical midplane technology in dense data storage systems and successfully demonstrated at 10.3 Gb/s. Active connectors incorporate optical transceiver interfaces operating at 850 nm and are connected in an in-plane coupling configuration to the embedded waveguides in the midplane. In addition a novel method of passively aligning and assembling passive optical devices to embedded polymer waveguide arrays has also been demonstrated.

  4. Development of components for IFOG-based inertial measurement units using polymer waveguide fabrication technologies

    NASA Astrophysics Data System (ADS)

    Ashley, P. R.; Temmen, M. G.; Diffey, W. M.; Sanghadasa, M.; Bramson, M. D.

    2007-10-01

    Active and passive polymer materials have been successfully used in the development of highly accurate, compact and low cost guided-wave components: an optical transceiver and a phase modulator, for inertial measurement units (IMUs) based on the interferometric fibre optic gyroscope (IFOG) technology for precision guidance in navigation systems. High performance and low noise transceivers with high optical power and good spectral quality were fabricated using a silicon-bench architecture. Low loss phase modulators with low halfwave drive voltage (Vπ) have been fabricated with a backscatter compensated design using polarizing waveguides consisting of CLD- and FTC-type high performance electro-optic (E-O) chromophores. Gyro bias stability of less than 0.02° h-1 has been demonstrated with these guided-wave components.

  5. Recent progress in InP/polymer-based devices for telecom and data center applications

    NASA Astrophysics Data System (ADS)

    Kleinert, Moritz; Zhang, Ziyang; de Felipe, David; Zawadzki, Crispin; Maese Novo, Alejandro; Brinker, Walter; Möhrle, Martin; Keil, Norbert

    2015-02-01

    Recent progress on polymer-based photonic devices and hybrid photonic integration technology using InP-based active components is presented. High performance thermo-optic components, including compact polymer variable optical attenuators and switches are powerful tools to regulate and control the light flow in the optical backbone. Polymer arrayed waveguide gratings integrated with InP laser and detector arrays function as low-cost optical line terminals (OLTs) in the WDM-PON network. External cavity tunable lasers combined with C/L band thinfilm filter, on-chip U-groove and 45° mirrors construct a compact, bi-directional and color-less optical network unit (ONU). A tunable laser integrated with VOAs, TFEs and two 90° hybrids builds the optical front-end of a colorless, dual-polarization coherent receiver. Multicore polymer waveguides and multi-step 45°mirrors are demonstrated as bridging devices between the spatialdivision- multiplexing transmission technology using multi-core fibers and the conventional PLCbased photonic platforms, appealing to the fast development of dense 3D photonic integration.

  6. Fast and accurate detection of cancer cell using a versatile three-channel plasmonic sensor

    NASA Astrophysics Data System (ADS)

    Hoseinian, M.; Ahmadi, A. R.; Bolorizadeh, M. A.

    2016-09-01

    Surface Plasmon Resonance (SPR) optical fiber sensors can be used as cost-effective small sized biosensors that are relatively simple to operate. Additionally, these instruments are label-free, hence rendering them highly sensitive to biological measurements. In this study, a three-channel microstructure optical fiber plasmonic-based portable biosensor is designed and analyzed using Finite Element Method. The proposed system is capable of determining changes in sample's refractive index with precision of order one thousandth. The biosensor measures three absorption resonance wavelengths of the analytes simultaneously. This property is one of the main advantages of the proposed biosensor since it reduces the error in the measured wavelength and enhances the accuracy of the results up to 10-5 m/RIU by reducing noise. In this paper, Jurkat cell, an indicator cell for leukemia cancer, is considered as the analyte; and its absorption resonance wavelengths as well as sensitivity in each channel are determined.

  7. A platform-based foot pressure/shear sensor

    NASA Astrophysics Data System (ADS)

    Chang, Chun-Te; Liu, Chao Shih; Soetanto, William; Wang, Wei-Chih

    2012-04-01

    The proposed research is aimed at developing, fabricating and implementing a flexible fiber optic bend loss sensor for the measurement of plantar pressure and shear stress for diabetic patients. The successful development of the sensor will greatly impact the study of diabetic foot ulcers by allowing clinicians to measure a parameter (namely, shear stress) that has been implicated in ulceration, but heretofore, has not been routinely quantified on high risk patients. A full-scale foot pressure/shear sensor involves a tactile sensor array using intersecting optical waveguides is presented. The basic configuration of the optical sensor systems incorporates a mesh that is comprised of two sets of parallel optical waveguide planes; the planes are configured so the parallel rows of waveguides of the top and bottom planes are perpendicular to each other. The planes are sandwiched together creating one sensing sheet. Two-dimensional information is determined by measuring the loss of light from each of the waveguide to map the overall pressure distribution. The shifting of the layers relative to each other allows determination of the shear stress in the plane of the sensor. This paper presents latest development and improvement in the sensors design. Fabrication and results from the latest tests will be described.

  8. Progress in chemical luminescence-based biosensors: A critical review.

    PubMed

    Roda, Aldo; Mirasoli, Mara; Michelini, Elisa; Di Fusco, Massimo; Zangheri, Martina; Cevenini, Luca; Roda, Barbara; Simoni, Patrizia

    2016-02-15

    Biosensors are a very active research field. They have the potential to lead to low-cost, rapid, sensitive, reproducible, and miniaturized bioanalytical devices, which exploit the high binding avidity and selectivity of biospecific binding molecules together with highly sensitive detection principles. Of the optical biosensors, those based on chemical luminescence detection (including chemiluminescence, bioluminescence, electrogenerated chemiluminescence, and thermochemiluminescence) are particularly attractive, due to their high-to-signal ratio and the simplicity of the required measurement equipment. Several biosensors based on chemical luminescence have been described for quantitative, and in some cases multiplex, analysis of organic molecules (such as hormones, drugs, pollutants), proteins, and nucleic acids. These exploit a variety of miniaturized analytical formats, such as microfluidics, microarrays, paper-based analytical devices, and whole-cell biosensors. Nevertheless, despite the high analytical performances described in the literature, the field of chemical luminescence biosensors has yet to demonstrate commercial success. This review presents the main recent advances in the field and discusses the approaches, challenges, and open issues, with the aim of stimulating a broader interest in developing chemical luminescence biosensors and improving their commercial exploitation. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Waveguide device and method for making same

    DOEpatents

    Forman, Michael A [San Francisco, CA

    2007-08-14

    A monolithic micromachined waveguide device or devices with low-loss, high-power handling, and near-optical frequency ranges is set forth. The waveguide and integrated devices are capable of transmitting near-optical frequencies due to optical-quality sidewall roughness. The device or devices are fabricated in parallel, may be mass produced using a LIGA manufacturing process, and may include a passive component such as a diplexer and/or an active capping layer capable of particularized signal processing of the waveforms propagated by the waveguide.

  10. Biosensors in Clinical Practice: Focus on Oncohematology

    PubMed Central

    Fracchiolla, Nicola S.; Artuso, Silvia; Cortelezzi, Agostino

    2013-01-01

    Biosensors are devices that are capable of detecting specific biological analytes and converting their presence or concentration into some electrical, thermal, optical or other signal that can be easily analysed. The first biosensor was designed by Clark and Lyons in 1962 as a means of measuring glucose. Since then, much progress has been made and the applications of biosensors are today potentially boundless. This review is limited to their clinical applications, particularly in the field of oncohematology. Biosensors have recently been developed in order to improve the diagnosis and treatment of patients affected by hematological malignancies, such as the biosensor for assessing the in vitro pre-treatment efficacy of cytarabine in acute myeloid leukemia, and the fluorescence resonance energy transfer-based biosensor for assessing the efficacy of imatinib in chronic myeloid leukemia. The review also considers the challenges and future perspectives of biosensors in clinical practice. PMID:23673681

  11. Y-junctions based on circular depressed-cladding waveguides fabricated with femtosecond pulses in Nd:YAG crystal: A route to integrate complex photonic circuits in crystals

    NASA Astrophysics Data System (ADS)

    Ajates, Javier G.; Romero, Carolina; Castillo, Gabriel R.; Chen, Feng; Vázquez de Aldana, Javier R.

    2017-10-01

    We have designed and fabricated photonic structures such as, Y-junctions (one of the basic building blocks for construction any integrated photonic devices) and Mach-Zehnder interferometers, based on circular depressed-cladding waveguides by direct femtosecond laser irradiation in Nd:YAG crystal. The waveguides were optically characterized at 633 nm, showing nearly mono-modal behaviour for the selected waveguide radius (9 μm). The effect of the splitting angle in the Y structures was investigated finding a good preservation of the modal profiles up to more than 2°, with 1 dB of additional losses in comparison with straight waveguides. The dependence with polarization of these splitters keeps in a reasonable low level. Our designs pave the way for the fabrication of arbitrarily complex 3D photonic circuits in crystals with cladding waveguides.

  12. A Urea Biosensor from Stacked Sol-Gel Films with Immobilized Nile Blue Chromoionophore and Urease Enzyme

    PubMed Central

    Alqasaimeh, Muawia Salameh; Heng, Lee Yook; Ahmad, Musa

    2007-01-01

    An optical urea biosensor was fabricated by stacking several layers of sol-gel films. The stacking of the sol-gel films allowed the immobilization of a Nile Blue chromoionophore (ETH 5294) and urease enzyme separately without the need of any chemical attachment procedure. The absorbance response of the biosensor was monitored at 550 nm, i.e. the deprotonation of the chromoionophore. This multi-layer sol-gel film format enabled higher enzyme loading in the biosensor to be achieved. The urea optical biosensor constructed from three layers of sol-gel films that contained urease demonstrated a much wider linear response range of up to 100 mM urea when compared with biosensors that constructed from 1-2 layers of films. Analysis of urea in urine samples with this optical urea biosensor yielded results similar to that determined by a spectrophotometric method using the reagent p-dimethylaminobenzaldehyde (R2 = 0.982, n = 6). The average recovery of urea from urine samples using this urea biosensor is approximately 103%.

  13. Surface Plasmon Resonance Biosensor Based on Smart Phone Platforms

    NASA Astrophysics Data System (ADS)

    Liu, Yun; Liu, Qiang; Chen, Shimeng; Cheng, Fang; Wang, Hanqi; Peng, Wei

    2015-08-01

    We demonstrate a fiber optic surface plasmon resonance (SPR) biosensor based on smart phone platforms. The light-weight optical components and sensing element are connected by optical fibers on a phone case. This SPR adaptor can be conveniently installed or removed from smart phones. The measurement, control and reference channels are illuminated by the light entering the lead-in fibers from the phone’s LED flash, while the light from the end faces of the lead-out fibers is detected by the phone’s camera. The SPR-sensing element is fabricated by a light-guiding silica capillary that is stripped off its cladding and coated with 50-nm gold film. Utilizing a smart application to extract the light intensity information from the camera images, the light intensities of each channel are recorded every 0.5 s with refractive index (RI) changes. The performance of the smart phone-based SPR platform for accurate and repeatable measurements was evaluated by detecting different concentrations of antibody binding to a functionalized sensing element, and the experiment results were validated through contrast experiments with a commercial SPR instrument. This cost-effective and portable SPR biosensor based on smart phones has many applications, such as medicine, health and environmental monitoring.

  14. Surface Plasmon Resonance Biosensor Based on Smart Phone Platforms.

    PubMed

    Liu, Yun; Liu, Qiang; Chen, Shimeng; Cheng, Fang; Wang, Hanqi; Peng, Wei

    2015-08-10

    We demonstrate a fiber optic surface plasmon resonance (SPR) biosensor based on smart phone platforms. The light-weight optical components and sensing element are connected by optical fibers on a phone case. This SPR adaptor can be conveniently installed or removed from smart phones. The measurement, control and reference channels are illuminated by the light entering the lead-in fibers from the phone's LED flash, while the light from the end faces of the lead-out fibers is detected by the phone's camera. The SPR-sensing element is fabricated by a light-guiding silica capillary that is stripped off its cladding and coated with 50-nm gold film. Utilizing a smart application to extract the light intensity information from the camera images, the light intensities of each channel are recorded every 0.5 s with refractive index (RI) changes. The performance of the smart phone-based SPR platform for accurate and repeatable measurements was evaluated by detecting different concentrations of antibody binding to a functionalized sensing element, and the experiment results were validated through contrast experiments with a commercial SPR instrument. This cost-effective and portable SPR biosensor based on smart phones has many applications, such as medicine, health and environmental monitoring.

  15. Low-cost integrated-optic fiber couplers

    NASA Astrophysics Data System (ADS)

    Sheem, Sang K.; Zhang, Feng; Choi, Jong-Ho; Lee, Yong-Woo; Low, Sarah; Lu, Shih-Yau

    1997-04-01

    In an effort to lower the cost of fiber optic couplers, integrated optic channel waveguide circuits are made of a UV-curable polymer using a molding technique, and then a novel fiber-to-channel connecting approach is employed in which UV light radiating from an optical fiber core cures the polymer in the channel, thus accomplishing a 'touchdown' of the core-extension waveguide onto the walls of the channel waveguide.

  16. Design of a Tunable, Room Temperature, Continuous-Wave Terahertz Source and Detector using Silicon Waveguides

    DTIC Science & Technology

    2008-01-30

    that will use conventional diode- or hotomultiplier-tube-based optical detectors , which are xtremely sensitive . . HEATING AND FREE-CARRIER IMITATIONS...CONTRACT NUMBER IN-HOUSE Design of a tunable, room temperature, continuous-wave terahertz source and detector using silicon waveguides 5b. GRANT...B 261Design of a tunable, room temperature, continuous-wave terahertz source and detector using silicon waveguides T. Baehr-Jones,1,* M. Hochberg,1,3

  17. An optical microplate biosensor for the detection of methyl parathion pesticide using a biohybrid of Sphingomonas sp. cells-silica nanoparticles.

    PubMed

    Mishra, Archana; Kumar, Jitendra; Melo, Jose Savio

    2017-01-15

    The previously developed Sphingomonas sp. based optical microplate biosensor for methyl parathion (MP) was good as it detected multiple samples but had poor stability and low sensitivity. The present study aims to overcome these limitations. Silica nanoparticles (Si NP) were thus functionalized with polyethyleneimine (PEI) and the functionalized silica nanoparticles ( f Si NP) were then integrated with Sphingomonas sp. cells. The process was optimized for hydrolysis of MP into p-nitrophenol (PNP). Integration of f Si NP with cells was confirmed by FT-IR analysis. Biohybrid of Sphingomonas sp.- f Si NP was immobilized on the wells of microplate and associated directly with the optical transducer of microplate reader. Immobilized biohybrid of Sphingomonas sp.- f Si NP was characterized using SEM. A detection range of 0.1-1ppm MP was achieved from the linear range of calibration plot. After integration with f Si NP the storage stability of biohybrid was enhanced ten times from 18 to 180 days. This study proves that after interaction of cells with f Si NP, improved the sensitivity and stability of the biosensor. Spiked samples were also analyzed and correlated using this biohybrid based biosensor. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. An optical biosensor using MEMS-based V-grooves

    NASA Astrophysics Data System (ADS)

    Tian, Ye; Ma, Xiaodong; Zou, Xiaotian; Wu, Nan; Wang, Xingwei

    2011-05-01

    An optical fiber biosensor featuring miniaturization, electromagnetic interference (EMI)-immunity, and flexibility is presented. The sensor was fabricated by aligning two gold-deposited optical single-mode fiber facets inside V-grooves on a silicon chip to form a Fabry-Perot (FP) cavity. The mirrors on the fiber facets were made of deposited gold (Au) films, which provided a high finesse to produce a highly sensitivity. Microelectromechanical systems (MEMS) fabrication techniques were used to precisely control the profile and angle of the V-grooves on the silicon. The biotin-terminated thiol molecule was firstly immobilized on the gold surface. Subsequently, the molecules of Neutravidin were specifically bound to the biotin-terminated self-assembled monolayers (SAMs). The induced changes of cavity length and refractive index (RI) upon the gold surface lead to an optical path difference (OPD) of the FP cavity, which was detected by demodulating the transmission spectrum phase shift. By taking advantage of MEMS techniques, multiple biosensors can be integrated into one small silicon chip for detecting various biomolecule targets simultaneously.

  19. In Vitro Evaluation of Fluorescence Glucose Biosensor Response

    PubMed Central

    Aloraefy, Mamdouh; Pfefer, T. Joshua; Ramella-Roman, Jessica C.; Sapsford, Kim E.

    2014-01-01

    Rapid, accurate, and minimally-invasive glucose biosensors based on Förster Resonance Energy Transfer (FRET) for glucose measurement have the potential to enhance diabetes control. However, a standard set of in vitro approaches for evaluating optical glucose biosensor response under controlled conditions would facilitate technological innovation and clinical translation. Towards this end, we have identified key characteristics and response test methods, fabricated FRET-based glucose biosensors, and characterized biosensor performance using these test methods. The biosensors were based on competitive binding between dextran and glucose to concanavalin A and incorporated long-wavelength fluorescence dye pairs. Testing characteristics included spectral response, linearity, sensitivity, limit of detection, kinetic response, reversibility, stability, precision, and accuracy. The biosensor demonstrated a fluorescence change of 45% in the presence of 400 mg/dL glucose, a mean absolute relative difference of less than 11%, a limit of detection of 25 mg/dL, a response time of 15 min, and a decay in fluorescence intensity of 72% over 30 days. The battery of tests presented here for objective, quantitative in vitro evaluation of FRET glucose biosensors performance have the potential to form the basis of future consensus standards. By implementing these test methods for a long-visible-wavelength biosensor, we were able to demonstrate strengths and weaknesses with a new level of thoroughness and rigor. PMID:25006996

  20. In vitro evaluation of fluorescence glucose biosensor response.

    PubMed

    Aloraefy, Mamdouh; Pfefer, T Joshua; Ramella-Roman, Jessica C; Sapsford, Kim E

    2014-07-08

    Rapid, accurate, and minimally-invasive glucose biosensors based on Förster Resonance Energy Transfer (FRET) for glucose measurement have the potential to enhance diabetes control. However, a standard set of in vitro approaches for evaluating optical glucose biosensor response under controlled conditions would facilitate technological innovation and clinical translation. Towards this end, we have identified key characteristics and response test methods, fabricated FRET-based glucose biosensors, and characterized biosensor performance using these test methods. The biosensors were based on competitive binding between dextran and glucose to concanavalin A and incorporated long-wavelength fluorescence dye pairs. Testing characteristics included spectral response, linearity, sensitivity, limit of detection, kinetic response, reversibility, stability, precision, and accuracy. The biosensor demonstrated a fluorescence change of 45% in the presence of 400 mg/dL glucose, a mean absolute relative difference of less than 11%, a limit of detection of 25 mg/dL, a response time of 15 min, and a decay in fluorescence intensity of 72% over 30 days. The battery of tests presented here for objective, quantitative in vitro evaluation of FRET glucose biosensors performance have the potential to form the basis of future consensus standards. By implementing these test methods for a long-visible-wavelength biosensor, we were able to demonstrate strengths and weaknesses with a new level of thoroughness and rigor.

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