Dr. von Braun With German Rocket Experimenters

NASA Technical Reports Server (NTRS)

1930-01-01

Dr. von Braun was among a famous group of rocket experimenters in Germany in the 1930s. This photograph is believed to be made on the occasion of Herman Oberth's Kegelduese liquid rocket engine being certified as to performance during firing. From left to right are R. Nebel, Dr. Ritter, Mr. Baermueller, Kurt Heinish, Herman Oberth, Klaus Riedel, Wernher von Braun, and an unidentified person.

Wernher von Braun

NASA Image and Video Library

1969-07-24

Apollo 11 splashdown celebration in Huntsville, Alabama, on July 24, 1969. Huntsville Alabama is the home of the Marshall Space Flight Center which developed the Saturn vehicles under the direction of Dr. von Braun. The photo shows Dr. von Braun speaking to the crowd at the Madison County Courthouse as Mayor Joe Davis, Madison County Commissioner James Record and City Council President Ken Johnson look on.

Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

NASA Technical Reports Server (NTRS)

1967-01-01

Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown leaving the suiting-up van wearing a pressure suit prepared for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

Wernher von Braun

NASA Image and Video Library

1969-07-24

Dr. von Braun is carried aloft on the shoulders of Huntsville city officials during the Apollo 11 celebration in Huntsville, Alabama, on July 24, 1969. Huntsville, Alabama is the home of the Marshall Space Flight Center which developed the Saturn vehicles under the direction of Dr. von Braun. The Apollo 11 lifted off in July and made the first marned lunar landing on the Moon.

Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

NASA Technical Reports Server (NTRS)

1967-01-01

Astronaut L. Gordon Cooper checks the neck ring of a space suit worn by Marshall Space Flight Center (MSFC) Director, Dr. von Braun before he submerges into the water of the MSFC Neutral Buoyancy Simulator (NBS). Wearing a pressurized suit and weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

Portrait of Dr. Von Braun with Walt Disney, 1954.

NASA Technical Reports Server (NTRS)

1954-01-01

Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

n/a

NASA Image and Video Library

1965-04-13

Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bennight, and Dr. von Braun.

Childhood Picture of Dr. von Braun

NASA Technical Reports Server (NTRS)

1912-01-01

This is a childhood picture of Dr. von Braun (center) with his brothers. Dr. Wernher von Braun was born in Wirsitz, Germany, March 23, 1912. His childhood dreams of marned space flight were fulfilled when giant Saturn rockets, developed under his direction at NASA's Marshall Space Flight Center, boosted the manned Apollo spacecraft to the Moon. His life was dedicated to expanding man's knowledge through the exploration of space.

Wernher von Braun

NASA Image and Video Library

1964-03-24

Marshall Space Flight Center Director Dr. Wernher von Braun presents Lady Bird Johnson with an inscribed hard hat during the First Lady's March 24, 1964 visit. While at the Marshall Center, Mrs. Johnson addressed Center employees, toured facilities and witnessed test firings of a Saturn I first stage and an F-1 engine. Dr. von Braun is wearing a Texas hat presented to him months earlier by Lyndon Johnson during a visit to the Johnson ranch in Texas.

Dr. Wernher Von Braun Memorial Dinner

NASA Image and Video Library

2017-10-26

The annual Dr. Wernher Von Braun Memorial Dinner was held at the U.S. Space and Rocket Center's Davidson Center on October 26, 2017 with Keynote speaker General John Hyten, Commander of U.S. Strategic Command. Emcee was Mark Larson of Mark Larson Media Services, Inc. Dr. Wernher Von Braun Memorial Scholarships were presented to 8 college students by the National Space Club. Educator of the Year was awarded to Tammy Thorpe; Community Service award was presented to Huntsville, Al. Mayor Tommy Battle. The Communications Award was presented to retired astronaut Dr. Mike Massimino. The Distinguished Science Award was presented to Dr. Martin Weisskopf. The Astronautics Engineer Award was presented to Douglas R. Cooke. The Dr. Wernher Von Braun Space Flight Trophy was presented to Robert Lightfoot.

von Braun and German Publisher

NASA Technical Reports Server (NTRS)

1969-01-01

In this photograph, Guenter Ogger of Capitol Magazine, West Germany, greets Marshall Space Flight Center Director, Dr. Wernher von Braun. Mr. Ogger interviewed the famous rocket scientist for his magazine.

Wernher von Braun with German Officers and Others

NASA Technical Reports Server (NTRS)

1942-01-01

General Erich Fellgiebel, head of the German Army Information Service during World War II, congratulates members of the von Braun rocket team from Peenemunde for their October 3, 1942 A4 flight. Pictured front center is General Erich Fellgiebel. Shaking hands are General Walter Dornberger (left) and General Janssen, commanding officer of Peenemuende with Rudolph Hermarn to their right. Picture left to right in the back row are Wernher von Braun, Captain Stoelzel, Luftwaffe, and Dr. Gerhard Reisig.

Dr. Wernher von Braun

NASA Technical Reports Server (NTRS)

2004-01-01

Dr. von Braun is looking out from a 10th floor window of building 4200 at the Marshall Space Flight Center (MSFC). He was the first Center Director and served as the Director from July 1960 through February 1970. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under the Project Paperclip (American acquisition of German rocket experts) to continue their rocket development work. In 1950, von Braun and his German Rocket Team (also called the Peenemuende Team) were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center (MSFC). Under Dr. von Braun's leadership, MSFC developed the Saturn V launch vehicle, which placed the first men, two American astronauts, on the Moon. Wernher von Braun's life was dedicated to expanding man's knowledge through the exploration of space.

Wernher von Braun

NASA Image and Video Library

1962-12-20

Dr. von Braun, Major General Francis McMorrow, and Alabama Governor, John Patterson (far left) participated in the ground breaking ceremony for the University of Alabama Research Institute in Huntsville, December 20, 1962.

Dr. von Braun with Original Mercury Astronauts

NASA Technical Reports Server (NTRS)

1959-01-01

Dr. Wernher von Braun, Director of the Army Ballistic Missile Agency's (ABMA) Development Operations Division, poses with the original Mercury astronauts in ABMA's Fabrication Laboratory during a 1959 visit. Inspecting Mercury-Redstone hardware are from left to right, Alan Shepard, Donald Deke Slayton, Virgil Gus Grissom, von Braun, Gordon Cooper, Wally Schirra, John Glenn, and Scott Carpenter. Project Mercury officially began October 7, 1958 as the United States' first manned space program.

Wernher von Braun

NASA Image and Video Library

1970-06-27

This photograph was taken after Dr. von Braun moved from his post as Director of the Marshall Space Flight Center (MSFC) to Deputy Associate Administrator for Planning at NASA Headquarters. On June 27, 1970, he visited the MSFC again during the center’s 10th anniversary to look at a mockup of the spacecraft that would later be known as Skylab. With von Braun are (left to right): Herman K. Weidner, director of Science and Engineering at MSFC, and James R. Thompson of the center’s Astrionics Laboratory.

Wernher von Braun

NASA Image and Video Library

1962-09-11

Marshall Space Flight Center Director Dr. Wernher von Braun explains a detail from a Saturn IB mockup and engine to President John F. Kennedy, Vice President Lyndon Johnson and other guests, September 11, 1962.

Wernher von Braun

NASA Image and Video Library

1959-03-03

Dr. von Braun, Director of the Development Operations Divisons, and Dr. Debus, Director of the Missile Firing Laboratory; Army Ballistic Missile Agency (ABMA), in the blockhouse during the launch of the Pioneer IV, March 3, 1959.

Dr. von Braun tours the North American Aviation

NASA Technical Reports Server (NTRS)

1962-01-01

Dr. Wernher von Braun, Director of the Marshall Space Flight Center (MSFC), during his tour of the Space Information Division of North American Aviation (NAA) in Downey, California, where the Saturn SII stage was developed.

Wernher von Braun

NASA Image and Video Library

1959-01-01

Marshall Space Flight Center Director Wernher von Braun presents General J.B. Medaris with a new golf bag. General Medaris, (left) was a Commander of the Army Ballistic Missile Agency (ABMA) in Redstone Arsenal, Alabama during 1955 to 1958.

Wernher von Braun

NASA Image and Video Library

1965-11-05

In this photograph, Marshall Space Flight Center Director, Dr. Wernher von Braun, presents a Co-Inventor’s award to MSFC employee Martin Hall of the Mechanical Engineering Laboratory during the NASA Anniversary ceremony.

Wernher von Braun

NASA Image and Video Library

1959-01-01

In this picture, Dr. Wernher von Braun, who was serving as Director of the Army Ballistic Missile Agency's (ABMA) Development Operations Division, is shown posed with his Mercedes 220SE automobile in front of Redstone Building 4488, which houses the ABMA.

Dr. von Braun Tours the North American Aviation

NASA Technical Reports Server (NTRS)

1962-01-01

Dr. Wernher von Braun, Director of the Marshall Space Flight Center (MSFC), during his tour of the Space information Division of North American Aviation (NAA) in Downey, California, where the Saturn SII stage was developed.

Wernher von Braun

NASA Image and Video Library

1967-08-28

Marshall Space Flight Center’s (MSFC) director, Dr. Wernher von Braun (right), inspects a component of a laser experiment being conducted in MSFC’s Space Sciences Laboratory during a tour on August 28, 1967.

Wernher von Braun

NASA Image and Video Library

1950-01-01

Dr. von Braun stands beside a model of the upper stage (Earth-returnable stage) of the three-stage launch vehicle built for the series of the motion picture productions of space flight produced by Walt Disney in the mid-1950's.

Wernher von Braun

NASA Image and Video Library

1962-01-01

Dr. Wernher von Braun, Director of the Marshall Space Flight Center (MSFC), during his tour of the Space information Division of North American Aviation (NAA) in Downey, California, where the Saturn SII stage was developed.

Wernher von Braun

NASA Image and Video Library

1964-10-14

This photograph, dated October 14, 1964, was taken at the Marned Spacecraft Center, now the Johnson Space Center in Houston, Texas. Dr. von Braun is shown looking over consoles in the Manned Spaceflight Control Center.

Wernher von Braun

NASA Image and Video Library

1960-11-03

Marshall Space Flight Center’s (MSFC) Director, Dr. Wernher von Braun, is pictured here with Army Ballistic Missile Agency’s (ABMA) Commanding General, J.B. Medaris, before a display of Army missles at the ABMA test lab.

Victor or Villain? Wernher von Braun and the Space Race

ERIC Educational Resources Information Center

O'Brien, Jason L.; Sears, Christine E.

2011-01-01

Set during the Cold War and space race, this historical role-play focuses on Wernher von Braun's involvement in and culpability for the use of slave laborers to produce V-2 rockets for Nazi Germany. Students will grapple with two central questions. Should von Braun have been allowed to emigrate to the United States given his affiliation with the…

Dr. Wernher Von Braun

NASA Technical Reports Server (NTRS)

1999-01-01

Shown viewing the Apollo telescope mockup are, from left to right, Charles Donlan, deputy associate administrator for manned space flight; Dr. Wernher Von Braun, Marshall Space Flight Center director; William Horton, astrionics lab; Dr. Thomas Paine, NASA deputy administrator; Warner Kuers, director of the ME lab.

Dr. von Braun With a Model of a Launch Vehicle

NASA Technical Reports Server (NTRS)

1950-01-01

Dr. von Braun stands beside a model of the upper stage (Earth-returnable stage) of the three-stage launch vehicle built for the series of the motion picture productions of space flight produced by Walt Disney in the mid-1950's.

Director von Braun Presents General Medaris With Golf Bag

NASA Technical Reports Server (NTRS)

1959-01-01

Marshall Space Flight Center Director Wernher von Braun presents General J.B. Medaris with a new golf bag. General Medaris, (left) was a Commander of the Army Ballistic Missile Agency (ABMA) in Redstone Arsenal, Alabama during 1955 to 1958.

The British Interplanetary Society - Val Cleaver and Wernher von Braun

NASA Astrophysics Data System (ADS)

Willhite, I. P.

This article is concerned with the early relationship between Wernher von Braun and the British Interplanetary Society (BIS). The BIS/Wernher von Braun/Val Cleaver correspondence files located here at the US Space & Rocket Center in Huntsville, Alabama are unparalleled. As one reads the stimulating comments between Cleaver and von Braun, the need to share their thoughts prevails. Following is an excerpt from one letter that whets ones appetite for more. 10 June 1951 Cleaver writes, “I'm so glad you enjoyed my last letter, and look forward to your promised further contribution to our discussion of the ethics of science in general and astronautics in particu- lar. As regards the one particular point on which you found yourself unable to hold your fire, I should say there are really two distinct issues at stake:. . .” This article attempts to represent the best of the letters as they goad each other on scientific principles, means to prevent wars, and other philosophic ideas.

Heritage Gallery

NASA Technical Reports Server (NTRS)

2002-01-01

Marshall Space Flight Center's (MSFC's) building 4200 hosts a new spaceflight history museum referred to as the Heritage Gallery, allowing employees and visitors alike to have the opportunity to experience history first hand. On display are many models of launch vehicles and spacecraft that have made the center famous. It features a full-scale mockup of the lunar roving vehicle, three built-in multimedia displays, a large theater screen, and two glass cases that house memorabilia such as personal items belonging to Wernher von Braun, MSFC's first Center Director. The new Heritage Gallery features the accomplishments of several past and present members of the Marshall team. Attending the ribbon cutting ceremony are: (left to right) Gerhard Reisig; Cort Durocher, executive director of the American Institute of Aeronautics and Astronautics; Ernst Stuhlinger; Konrad Darnenburg; Werner Dahm; Walter Jacobi; and host of event, Center Director Art Stephenson.

Dr. von Braun Visits Huntsville Boys Club

NASA Technical Reports Server (NTRS)

1961-01-01

Dr. von Braun, Director of Marshall Space Flight Center (MSFC) and chairman of this year's United Givers Fund (UGF) drive at MSFC, takes time out from the problems of sending a man to the Moon to talk baseball with 11-year-old Randy Smith at the Huntsville Boys Club.

Around Marshall

NASA Image and Video Library

2002-10-30

Marshall Space Flight Center's (MSFC's) building 4200 hosts a new spaceflight history museum referred to as the Heritage Gallery, allowing employees and visitors alike to have the opportunity to experience history first hand. On display are many models of launch vehicles and spacecraft that have made the center famous. It features a full-scale mockup of the lunar roving vehicle, three built-in multimedia displays, a large theater screen, and two glass cases that house memorabilia such as personal items belonging to Wernher von Braun, MSFC's first Center Director. The new Heritage Gallery features the accomplishments of several past and present members of the Marshall team. Attending the ribbon cutting ceremony are: (left to right) Gerhard Reisig; Cort Durocher, executive director of the American Institute of Aeronautics and Astronautics; Ernst Stuhlinger; Konrad Darnenburg; Werner Dahm; Walter Jacobi; and host of event, Center Director Art Stephenson.

NASA evolution of exploration architectures

NASA Technical Reports Server (NTRS)

Roberts, Barney B.

1991-01-01

A series of charts and diagrams is used to provide a detailed overview of the evolution of NASA space exploration architectures. The pre-Apollo programs including the Werner von Braun feasibility study are discussed and the evolution of the Apollo program itself is treated in detail. The post-Apollo era is reviewed and attention is given to the resurgence of strategic planning exemplified by both ad hoc and formal efforts at planning. Results of NASA's study of the main elements of the Space Exploration Initiative which examined technical scenarios, science opportunities, required technologies, international considerations, institutional strengths and needs, and resource estimates are presented. The 90-day study concludes that, among other things, major investments in challenging technologies are required, the scientific opportunities provided by the program are considerable, current launch capabilities are inadequate, and Space Station Freedom is essential.

Saturn V Arrives at Launch Pad Complex 39

NASA Technical Reports Server (NTRS)

1969-01-01

The Saturn V launch vehicle (AS-506) carrying the Apollo 11 spacecraft, arrived at the launch pad complex 39 at the Kennedy Space Center (KSC) on May 20, 1969. On July 16, 1969, the 363 foot tall, 6,400,000 pound rocket, developed by the Marshall Space Flight Center (MSFC) under the direction of Werner von Braun, hurled the spacecraft into Earth parking orbit and then placed it on the trajectory to the moon for man's first lunar landing. Aboard the spacecraft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The crew safely splashed down into the Pacific Ocean on July 24, 1969. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Wernher von Braun

NASA Image and Video Library

1965-04-13

Walt Disney toured the West Test Area during his visit to the Marshall Space Flight Center on April 13, 1965. The three in center foreground are Karl Heimburg, Director, Test Division; Dr. von Braun, Director, MSFC; and Walt Disney. The Dynamic Test Stand with the S-1C stage being installed is in the background.

Wernher von Braun

NASA Image and Video Library

1964-10-14

This photograph is dated October 14, 1964, and shows Dr. von Braun, left, during a tour of the NASA Marned Spacecraft Center, now the Johnson Space Center. He is with Dr. J.P. Kuettner, center, from the Marshall Space Flight Center, and Warren J. North from the Manned Spacecraft Center.

Wernher von Braun

NASA Image and Video Library

1954-07-01

Dr. Wernher von Braun (center), then Chief of the Guided Missile Development Division at Redstone Arsenal, Alabama, discusses a "bottle suit" model with Dr. Heinz Haber (left), an expert on aviation medicine, and Willey Ley, a science writer on rocketry and space exploration. The three men were at the Disney studios appearing in the motion picture, entitled "Man in Space."

Wernher von Braun

NASA Image and Video Library

1961-10-19

Dr. Wernher von Braun holds the coveted Hermarn Oberth award presented to him by Professor Oberth during the banquet hosted by the Alabama Section of the American Rocket Society (ARS), on October 19, 1961. The Oberth award was given for outstanding technical contributions to the field of astronautics or for the promotion and advancement of astronautical sciences.

Wernher von Braun

NASA Image and Video Library

1959-03-04

Dr. Wernher von Braun, Director of the U.S. Army Ballistic Missile Agency's (ABMA) Development Operations Division, talks to Huntsville Mayor R. B. "Speck" Searcy, center, and Army Ordnance Missile Command (ARMC) Major General John B. Medaris, right, during "Moon Day" celebrations in downtown Huntsville, Alabama. (Courtesy of Huntsville/Madison County Public Library)

Wernher von Braun

NASA Image and Video Library

1965-05-25

In this photo, Dr. von Braun anxiously awaits the launch of the Saturn I vehicle (SA-8) in the Launch Complex Control Center at the Kennedy Space Center in Florida on May 25, 1965. The SA-8 mission made the first night launch and deployed the Pegasus II micro meteoroid detection satellite.

Dr. Wernher Von Braun

NASA Technical Reports Server (NTRS)

1999-01-01

Marshall Space Flight Center director Wernher Von Braun and his family were honored with a series of events prior to his relocation to Washington, D.C. where he was assigned duties at NASA headquarters as deputy associate administrator for planning. Here he is shown with General Richard Drury and Hazel Toftoy, widow of General H.N. Toftoy.

Albert Einstein and Wernher von Braun - the two great German-American physicists seen in a historical perspective.

NASA Astrophysics Data System (ADS)

Winterberg, Friedwardt

2008-04-01

It was Albert Einstein who for the first time changed our view of the universe to be a non-euclidean curved space-time. And it was Wernher von Braun who blazed the trail to take us into this universe, leaving for the first time the gravitational field of our planet earth, with the landing a man on the moon the greatest event in human history. Both these great physicists did this on the shoulders of giants. Albert Einstein on the shoulders of his landsman, the mathematician Bernhard Riemann, and Wernher von Braun on the shoulders of Goddard and Oberth. Both Einstein and von Braun made a Faustian pact with the devil, von Braun by accepting research funds from Hitler, and Einstein by urging Roosvelt to build the atom bomb (against Hitler). Both of these great men later regretted the use of their work for the killing of innocent bystanders, even though in the end the invention of nuclear energy and space flight is for the benefit of man. Their example serves as a warning for all of us. It can be formulated as follows: ``Can I in good conscience accept research funds from the military to advance scientific knowledge, for weapons developed against an abstract enemy I never have met in person?'' Weapons if used do not differentiate between the scientist, who invented these weapons, and the non-scientist.

Professor Oberth and Dr. von Braun at ARS Banquet

NASA Technical Reports Server (NTRS)

1961-01-01

Dr. Wernher von Braun holds the coveted Hermarn Oberth award presented to him by Professor Oberth during the banquet hosted by the Alabama Section of the American Rocket Society (ARS), on October 19, 1961. The Oberth award was given for outstanding technical contributions to the field of astronautics or for the promotion and advancement of astronautical sciences.

Citizenship Ceremony for Dr. von Braun and German-Born Scientists and Engineers

NASA Technical Reports Server (NTRS)

1955-01-01

In a swearing-in ceremony held at Huntsville High School, one hundred and three German-born scientists and engineers, along with family members, took the oath of citizenship to become United States citizens. Among those taking the oath was Dr. Wernher von Braun, located in the second row, right side, third from the end.

Wernher von Braun

NASA Image and Video Library

1959-01-21

In this photo, (left to right) Army Ballistic Missile Agency (ABMA) Missile Firing Laboratory Chief Dr. Kurt Debus, Director of the ABMA Development Operations Division, Dr. von Braun and an unidentified individual in blockhouse during the CM-21 (Jupiter) firing. The Jupiter missile CM-21 became the first Chrysler production qualification missile to be fired and in March 1959 launched the Pioneer IV.

Wernher von Braun

NASA Image and Video Library

1958-01-31

Jet Propulsion Laboratory Director Dr. James Pickering, Dr. James van Allen of the State University of Iowa, and Army Ballistic missionile Agency Technical Director Dr. Wernher von Braun triumphantly display a model of the Explorer I, America's first satellite, shortly after the satellite's launch on January 31, 1958. The Jet Propulsion Laboratory packed and tested the payload, a radiation detection experiment designed by Dr. van Allen. Dr. von Braun's rocket team at Redstone Arsenal in Huntsville, Alabama, developed the Juno I launch vehicle, a modified Jupiter-C.

Wernher von Braun

NASA Image and Video Library

1963-03-28

Dr. von Braun, Director of the Marshall Space Flight Center (MSFC), and Dr. Debus, Director of the Launch Operations Center, at Complex 34 prior to the Launch of the SA-4 (the fourth flight of Saturn I), March 28, 1963. The mission conducted the second "Project Highwater" experiment, which the upper stage ejected 30,000 gallons of ballast water in the upper atmosphere for a physics experiment.

Dr. von Braun Relaxes After the Successful Launch of Apollo 11

NASA Technical Reports Server (NTRS)

1969-01-01

Dr. Wernher von Braun, first director of the Marshall Space Flight Center, relaxes following the successful launch of the Saturn V carrying Apollo 11 to the moon. The towering 363-foot Saturn V was a multi-stage, multi-engine launch vehicle standing taller than the Statue of Liberty. Altogether, the Saturn V engines produced as much power as 85 Hoover Dams.

Sputnik

NASA Technical Reports Server (NTRS)

1957-01-01

The Army Ballistic Missile Agency incorporated the von Braun team in key positions with Dr. von Braun as a head of the Development Operations Division. On October 4, 1957, the Nation was shocked when the Russians launched Sputnik, the world's first artificial satellite. Two months later, the United States suffered disappointment when a Navy Vanguard rocket, with its satellite payload, failed to develop sufficient thrust and toppled over on the launch pad.

Wernher von Braun: Reflections on His Contributions to Space Exploration

NASA Technical Reports Server (NTRS)

Goldman, Arthur E.

2012-01-01

In 1950, Dr. Wernher von Braun and approximately 100 of his team members came to Huntsville, Alabama, to begin work with the Army on what would later become America's historic space program. He would later serve as the first director of the Marshall Space Flight Center and led the development of the Saturn V launch vehicle that launched seven crewed American mission to the moon, as well as America s first space station, Skylab. Von Braun is best known for his team s technical achievements. He realized his dream of exploring outer space by helping place humans on the moon. His engineering and managerial talent during the Apollo era had contributed to a technological revolution. He was by all accounts a good engineer, but he was only one among many. What set Von Braun apart were his charisma, his vision, and his leadership skills. He inspired loyalty and dedication in the people around him. He understood the importance of communicating his vision to his team, to political and business leaders and the public. Today, the Marshall Center continues his vision by pursuing engineering and scientific projects that will continue to open space to exploration. This presentation will discuss Von Braun's impact on Huntsville, the Marshall Center, the nation and the world and look at his contributions in context of where world space exploration is today.

Early Rockets

NASA Image and Video Library

1957-10-04

The Army Ballistic Missile Agency incorporated the von Braun team in key positions with Dr. von Braun as a head of the Development Operations Division. On October 4, 1957, the Nation was shocked when the Russians launched Sputnik, the world's first artificial satellite. Two months later, the United States suffered disappointment when a Navy Vanguard rocket, with its satellite payload, failed to develop sufficient thrust and toppled over on the launch pad.

Mercury Project

NASA Image and Video Library

1959-01-01

Dr. Wernher von Braun, Director of the Army Ballistic Missile Agency's (ABMA) Development Operations Division, poses with the original Mercury astronauts in ABMA's Fabrication Laboratory during a 1959 visit. Inspecting Mercury-Redstone hardware are from left to right, Alan Shepard, Donald Deke Slayton, Virgil Gus Grissom, von Braun, Gordon Cooper, Wally Schirra, John Glenn, and Scott Carpenter. Project Mercury officially began October 7, 1958 as the United States' first manned space program.

Dr. Wernher Von Braun near the mobile launcher.

NASA Technical Reports Server (NTRS)

1999-01-01

Dr. George Mueller, NASA associate administrator for manned space flight, and Dr. Wernher Von Braun (right), director of the Marshall Space Flight Center, are seen near the mobile launcher carrying a 363 foot tall Saturn V space launch vehicle as the rocket is rolled from the vehicle assembly building at KSC for its three mile trip to the launch pad.

Wernher von Braun

NASA Image and Video Library

1968-10-01

Dr. von Braun, Director of the Marshall Space Flight Center (MSFC), greets Commander of Apollo 7 mission, Walter M. Schirra, Jr., during the mission briefing at Kennedy Space Center (KSC). The Apollo 7 mission, boosted by a Saturn IB launch vehicle on October 11, 1968, was the first flight of the Apollo spacecraft with crew. Other crew members were Astronaut Donn Eisele and Astronaut Walter Cunningham.

Wernher von Braun

NASA Image and Video Library

1968-10-01

Dr. von Braun inside the KC-135 in flight. The KC-135 provide NASA's Reduced-Gravity Program the unique weightlessness or zero-g environment of space flight for testing and training of human and hardware reactions. The recent version, KC-135A, is a specially modified turbojet transport which flies parabolic arcs to produce weightlessness periods of 20 to 25 seconds and its cargo bay test area is approximately 60 feet long, 10 feet wide, and 7 feet high.

Wernher von Braun

NASA Image and Video Library

1966-06-21

Dr. Joseph Randall, a laser expert at Marshall Space Flight Center (MSFC), explains one of the projects he is working on to a group composed of Federal Republic of Germany and MSFC officials. From left are: Dr. Randall; Minister for Scientific Research of Federal Republic of Germany, Dr. Gerhard Stolenberg; Director of MSFC Astrionics Lab, Dr. Walter Haeusserman; Head of Space Research Federal Republic of Germany, Max Mayer; MSFC Director Dr. von Braun; MSFC Deputy Director Dr. Elberhard Rees.

Around Marshall

NASA Image and Video Library

1970-01-01

Dr. Eberhard Rees served as director of the Marshall Space Flight Center from March 1, 1970 until January 19, 1973 when he retired from NASA. Prior to his appointment as Director, Rees served as the Center's deputy director under Dr. Wernher von Braun, 1960-1970. Rees came to the United States as part of the Dr. Wernher von Braun's German Rocket team following World War II. He transferred to Huntsville, Alabama from Fort Bliss, Texas in 1950 to work for the Army's rocket program at Redstone Arsenal. From 1956 to 1960 he served as deputy director of development operations at the Army Ballistic Missile Agency under von Braun. In 1960 Rees was transferred to NASA's Marshall Center.

Dr. von Braun and Dr. Stuhlinger With a Model of the Nuclear-Electric Vehicles

NASA Technical Reports Server (NTRS)

2004-01-01

In this photo, taken at the Walt Disney Studios in California, Dr. Wernher von Braun and Dr. Ernst Stuhlinger are shown discussing the concepts of nuclear-electric spaceships designed to undertake the mission to the planet Mars. As a part of the Disney 'Tomorrowland' series on the exploration of space, the nuclear-electric vehicles were shown in the last three television films, entitled 'Mars and Beyond,' which first aired in December 1957.

Dr. von Braun In Front of a Display of Missiles

NASA Technical Reports Server (NTRS)

1960-01-01

In this photo, Director of the US Army Ballistic Missile Agency (ABMA) Development Operations Division, Dr. Wernher von Braun, is standing before a display of Army missiles celebrating ABMA's Fourth Open House. The missiles in the background include (left to right) a satellite on a Juno II shroud with a Nike Ajax pointing left in front of a Jupiter missile. The Lacrosse is in front of the Juno II. The Nike Hercules points skyward in front of the Juno II and the Redstone.

Werner Heisenberg and Carl Friedrich Freiherr von Weizsäcker: A Fifty-Year Friendship*

NASA Astrophysics Data System (ADS)

Cassidy, David C.

2015-03-01

This paper follows Werner Heisenberg and Carl Friedrich von Weizsäcker during their fifty-year friendship from 1926, when they first met in Copenhagen, to Heisenberg's death in Munich in 1976. The relationship underwent profound changes during that period, as did physics, philosophy, and German society and politics, all of which exerted important influences on their lives, work, and interactions with each other. The nature of these developments and their impact are explored in this paper.

Wernher von Braun

NASA Image and Video Library

1960-01-01

In this photo, Director of the US Army Ballistic Missile Agency (ABMA) Development Operations Division, Dr. Wernher von Braun, is standing before a display of Army missiles celebrating ABMA's Fourth Open House. The missiles in the background include (left to right) a satellite on a Juno II shroud with a Nike Ajax pointing left in front of a Jupiter missile. The Lacrosse is in front of the Juno II. The Nike Hercules points skyward in front of the Juno II and the Redstone.

Von Braun Rocket Team at Fort Bliss, Texas

NASA Technical Reports Server (NTRS)

1940-01-01

The German Rocket Team, also known as the Von Braun Rocket Team, poses for a group photograph at Fort Bliss, Texas. After World War II ended in 1945, Dr. Wernher von Braun led some 120 of his Peenemuende Colleagues, who developed the V-2 rocket for the German military during the War, to the United Sttes under a contract to the U.S. Army Corps as part of Operation Paperclip. During the following five years the team worked on high altitude firings of the captured V-2 rockets at the White Sands Missile Range in New Mexico, and a guided missile development unit at Fort Bliss, Texas. In April 1950, the group was transferred to the Army Ballistic Missile Agency (ABMA) at Redstone Arsenal in Huntsville, Alabama, and continued to work on the development of the guided missiles for the U.S. Army until transferring to a newly established field center of the National Aeronautic and Space Administration (NASA), George C. Marshall Space Flight Center (MSFC).

Wernher von Braun

NASA Image and Video Library

1965-05-25

This image depicts the tension in the Launch Control Center of the Launch Complex 37 at Cape Canaveral, Florida, during the SA-8 on May 25, 1965. Pointing, center is Dr. Kurt Debus, Director, Launch Operations Directorate, MSFC. To the right is Dr. Hans Gruene, Deputy Director, Launch Operations Directorate, MSFC; Dr. von Braun, Director, Marshall Space Flight Center (MSFC); and leaning, Dr. Eberhard Rees, Director, Deputy Director for Research and Development, MSFC. The SA-8 mission, with a Saturn I launch vehicle, made the first night launch and deployed Pegasus II, micrometeoroid detection satellite.

Rocket center Peenemünde — Personal memories

NASA Astrophysics Data System (ADS)

Dannenberg, Konrad; Stuhlinger, Ernst

Von Braun built his first rockets as a young teenager. At 14, he started making plans for rockets for human travel to the Moon and Mars. The German Army began a rocket program in 1929. Two years later, Colonel (later General) Becker contacted von Braun who experimented with rockets in Berlin, gave him a contract in 1932, and, jointly with the Air Force, in 1936 built the rocket center Peenemünde where von Braun and his team developed the A-4 (V-2) rocket under Army auspices, while the Air Force developed the V-1 (buzz bomb), wire-guided bombs, and rocket planes. Albert Speer, impressed by the work of the rocketeers, allowed a modest growth of the Peenemünde project; this brought Dannenberg to the von Braun team in 1940. Hitler did not believe in rockets; he ignored the A-4 project until 1942 when he began to support it, expecting that it could turn the fortunes of war for him. He drastically increased the Peenemünde work force and allowed the transfer of soldiers from the front to Peenemünde; that was when Stuhlinger, in 1943, came to Peenemünde as a Pfc.-Ph.D. Later that year, Himmler wrenched the authority over A-4 production out of the Army's hands, put it under his command, and forced production of the immature rocket at Mittelwerk, and its military deployment against targets in France, Belgium, and England. Throughout the development of the A-4 rocket, von Braun was the undisputed leader of the project. Although still immature by the end of the war, the A-4 had proceeded to a status which made it the first successful long-range precision rocket, the prototype for a large number of military rockets built by numerous nations after the war, and for space rockets that launched satellites and traveled to the Moon and the planets.

Hot and Cold Therapy Eases Pain

NASA Technical Reports Server (NTRS)

2004-01-01

In the 1960s, NASA civil servant Tom Hughes worked for Marshall Space Flight Center s Quality Control Laboratory as a systems engineer. Reporting directly to Dr. Wernher von Braun, Marshall s first director, Hughes was assigned as a NASA representative for quality control at the Michoud Assembly Facility in New Orleans, Louisiana, to oversee the Saturn V rocket project. During this time, Hughes invented several technologies to improve the safety of the rocket, earning several commendations from von Braun. He also gained technical expertise in microwave technology, as NASA researched it to determine its relationship to radar.

Wernher von Braun

NASA Image and Video Library

1959-03-01

In this photo, Director of the U.S. Army Ballistic Missile Agency's (ABMA) Development Operations Division, Dr. Wernher von Braun, and Director of Missile Firing Division, Dr. Kurt Debus, are shown with unidentified individuals, discussing two components that would make up the Pioneer IV Lunar Probe. The mercury batteries (left) were used to power the radio transmitter, cosmic radiation counter and other instruments in Pioneer IV. The conical shroud placed over the instruments of Pioneer IV was plated with gold to improve conductivity. The metal surface also served as the anterna for the probe's instruments signaling back to the Earth receiving stations.

Dr. Wernher Von Braun

NASA Technical Reports Server (NTRS)

1999-01-01

Dr. Thomas Paine, Deputy Administrator of the National Aeronautics and Space Administration, examines an ordinary man's shoe outfitted for use in the Saturn I workshop. Pictured from the left in the Saturn I workshop mockup are William Brooksbank, propulsion and vehicle engineering laboratory; Dr. Paine; Dr. Wernher Von Braun, Marshall Center director; Colonel Clare F. Farley, Executive Officer in the Office Of The Administrator; and Charles J. Donlan, Deputy Associate Administrator for Manned Space Flight, Technical. the shoe Dr. Paine is holding has a unique fastener built into the sole to allow an astronaut to move about on the workshop floor and to remain in one position if he desires.

Space Station

NASA Image and Video Library

1952-01-01

This is a von Braun 1952 space station concept. In a 1952 series of articles written in Collier's, Dr. Wernher von Braun, then Technical Director of the Army Ordnance Guided Missiles Development Group at Redstone Arsenal, wrote of a large wheel-like space station in a 1,075-mile orbit. This station, made of flexible nylon, would be carried into space by a fully reusable three-stage launch vehicle. Once in space, the station's collapsible nylon body would be inflated much like an automobile tire. The 250-foot-wide wheel would rotate to provide artificial gravity, an important consideration at the time because little was known about the effects of prolonged zero-gravity on humans. Von Braun's wheel was slated for a number of important missions: a way station for space exploration, a meteorological observatory and a navigation aid. This concept was illustrated by artist Chesley Bonestell.

MSFC Director welcomes attendees to the 10th Annual Wernher von

NASA Image and Video Library

2017-10-26

Marshall Space Flight Center director Todd May welcomes attendees to the 10th annual Dr. Wernher von Braun Memorial Symposium held at the University of Alabama, Huntsville, Alabama. The three-day symposium brought together experts for discussion panels on science, engineering and technology under the theme “Gateways in Space: Exploration, Security, and Commerce.”

Physikgeschichte Das Rätsel bleibt

NASA Astrophysics Data System (ADS)

Hoffmann, Dieter

2002-05-01

Die jüngst erfolgte Veröffentlichung von Dokumenten aus dem Privatarchiv der Familie Bohr [1] über den geheimnisumwitterten Besuch von Werner Heisenberg in Kopenhagen im September 1941 hat in den deutschen Medien große Resonanz gefunden [2]. Tatsächlich verraten uns die jetzt veröffentlichten Dokumente sehr viel mehr über die Zeit ihres Entstehens als über den Besuch selbst.

Wernher von Braun

NASA Image and Video Library

2004-04-15

A pioneer of America's space program, Dr. von Braun stands by the five F-1 engines of the Saturn V launch vehicle. This Saturn V vehicle is an actual test vehicle which has been displayed at the U.S. Space Rocket Center in Huntsville, Alabama. Designed and developed by Rocketdyne under the direction of the Marshall Space Flight Center, a cluster of five F-1 engines was mounted on the Saturn V S-IC (first) stage. The engines measured 19-feet tall by 12.5-feet at the nozzle exit and burned 15 tons of liquid oxygen and kerosene each second to produce 7,500,000 pounds of thrust. The S-IC stage is the first stage, or booster, of a 364-foot long rocket that ultimately took astronauts to the Moon.

Operational Implications of the NATO Strategic Concept 2010 for European Countries in NATO and the EU

DTIC Science & Technology

2011-12-01

ofthe Operational Art, by Michael 0 . Krause and Cody R. Phillips (Washington D.C.: Center of Military History, 2007), 444. The level of multinational...Werner, and Wolfgang Fett. Bericht uber das gemeinsame Berliner Colloquium 2009 von Clausewitz-Gesellschafi und Bundesakademie fiir Sicherheilspolitik...Vol. 5, in Die Jahrbiicher der C/ausewitz-Gesellschafi e. V. - Jahrbuch 2009, by Werner Baach and Wolfgang Fett, 13-24. Hamburg: C lausewitz

Apollo 13 Debrief - Postflight

NASA Image and Video Library

1970-04-21

S70-35748 (20 April 1970) --- Dr. Donald K. Slayton (center foreground), MSC director of flight crew operations, talks with Dr. Wernher von Braun (right), famed rocket expert, at an Apollo 13 postflight debriefing session. The three crewmen of the problem-plagued Apollo 13 mission (left to right) in the background are astronauts James A Lovell Jr., commander; John L. Swigert Jr., command module pilot; and Fred W. Haise Jr., lunar module pilot. The apparent rupture of oxygen tank number two in the Apollo 13 Service Module (SM) and the subsequent damage forced the three astronauts to use the Lunar Module (LM) as a "lifeboat" to return home safely after their moon landing was canceled. Dr. von Braun is the deputy associate administrator for planning of the National Aeronautics and Space Administration (NASA).

Werner Heisenberg zum 100. Geburtstag: Pionier der Quantenmechanik

NASA Astrophysics Data System (ADS)

Jacobi, Manfred

2001-11-01

Werner Heisenberg war eine der prägendsten Gestalten der Physik des 20. Jahrhunderts. Zu seinen wichtigsten Verdiensten gehören die Grundlegung der Quantenmechanik, die Formulierung der Unschärferelationen sowie die Beteiligung an der Ausarbeitung der Kopenhagener Deutung der Quantenmechanik. Darüber hinaus lieferte er Arbeiten von fundamentalem Charakter zur Theorie des Atomkerns, zur kosmischen Strahlung und zur Quantenfeldtheorie. Während des Krieges war er an den Arbeiten des Uranvereins beteiligt, der die Möglichkeit einer Entwicklung von Kernwaffen untersuchte, jedoch über Vorarbeiten zur Reaktorphysik nicht hinauskam. Wegen dieser Tätigkeit wurde er bei Kriegsende für einige Monate in England interniert. Nach seiner Rückkehr widmete er sich vor allem dem Aufbau der Physik in Deutschland, die während der NS-Zeit nahezu ihrer gesamten Substanz beraubt worden war.

Dr. von Braun Standing by Five F-1 Engines

NASA Technical Reports Server (NTRS)

2004-01-01

A pioneer of America's space program, Dr. von Braun stands by the five F-1 engines of the Saturn V launch vehicle. This Saturn V vehicle is an actual test vehicle which has been displayed at the U.S. Space Rocket Center in Huntsville, Alabama. Designed and developed by Rocketdyne under the direction of the Marshall Space Flight Center, a cluster of five F-1 engines was mounted on the Saturn V S-IC (first) stage. The engines measured 19-feet tall by 12.5-feet at the nozzle exit and burned 15 tons of liquid oxygen and kerosene each second to produce 7,500,000 pounds of thrust. The S-IC stage is the first stage, or booster, of a 364-foot long rocket that ultimately took astronauts to the Moon.

Early Rockets

NASA Image and Video Library

1957-10-03

America’s first scientific satellite, the Explorer I, carried the radiation detection experiment designed by Dr. James Van Allen and discovered the Van Allen Radiation Belt. It was launched aboard a modified redstone rocket known as the Jupiter C, developed by Dr. von Braun’s rocket team at Redstone Arsenal in Huntsville, Alabama. The satellite launched on January 31, 1958, just 3 months after the the von Braun team received the go-ahead.

Keeping the Edge. Air Force Materiel Command Cold War Context (1945-1991). Volume 1: Command Lineage Scientific Achievement and Major Tenant Missions

DTIC Science & Technology

2003-08-01

Gerhard Braun, Dr. Rudolf Edse, Dr. Wolfgang Noeggerath, Hans Rister, and Dr. Theodor Zobel. (Dr. von Braun and the four other rocket specialists...Heinrich Albers, Herman Bottenhorn, Gerhard Krause , Dr. Ernst Kugel, and Hermann Nehlsen to Loewy Hydropress, Inc., in New York, while Dr. Claus...March 1948, Air Materiel Command maintained the Watson- and Cambridge-assigned German scientists at status quo, but added Dr. Wolfgang Pfister the next

Mary J. "Niki" Werkheiser presented Space Technology Award

NASA Image and Video Library

2017-10-26

Mary J. "Niki" Werkheiser is presented the 2016 Space Technology Award during proceedings at the 10th annual Dr. Wernher von Braun Memorial Symposium at the University of Alabama, Huntsville, Alabama.

Wernher von Braun

NASA Image and Video Library

1971-07-26

During the Apollo 15 launch activities in the launch control center's firing room 1 at Kennedy Space Center, Dr. Wernher von Braun, NASA's Deputy Associate Administrator for planning, takes a closer look at the launch pad through binoculars. The fifth manned lunar landing mission, Apollo 15 (SA-510), carrying a crew of three astronauts: Mission commander David R. Scott, Lunar Module pilot James B. Irwin, and Command Module pilot Alfred M. Worden Jr., lifted off on July 26, 1971. Astronauts Scott and Irwin were the first to use a wheeled surface vehicle, the Lunar Roving Vehicle, or the Rover, which was designed and developed by the Marshall Space Flight Center, and built by the Boeing Company. Astronauts spent 13 days, nearly 67 hours, on the Moon's surface to inspect a wide variety of its geological features.

The First Robotics Rocket City Regional Competition

NASA Image and Video Library

2018-03-16

The First Robotics Rocket City Regional Competition was held at the Von Braun Civic Center in Huntsville, Alabama on March 16, 2018. High school robotics teams from throughout the U.S., as well as a team from Brazil, competed.

Around Marshall

NASA Image and Video Library

1962-03-08

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation’s space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. The subcommittee was briefed on MSFC’s manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. In this photograph, MSFC Director, Dr. Wernher von Braun meets with Congressmen in the MSFC boardroom. Pictured from left to right are: Jack Cramer, NASA Headquarters; Joe Waggoner, Democratic representative of Louisiana; John W. Davis, Democratic representative of Georgia; R. Walter Riehlman, Republican representative of New York; Olin E. Teague, Democratic representative of Texas; Dr. Wernher von Braun, Director of MSFC; James G. Fulton, Republican representative of Pennsylvania; Ken Hechler, Democratic representative of West Virginia; and Erich Neubert of MSFC.

Space Travel is Utter Bilge: Early Ideas on Interplanetary Exploration

NASA Astrophysics Data System (ADS)

Yeomans, D. K.

2003-12-01

Until a few decades ago, interplanetary travel was the stuff of dreams but the dreamers often turned out to be farsighted while the predictions of some eminent scientists were far too conservative. The prescient dreamers include the Russian schoolteacher, Konstanin Tsiolkovsky who, in 1883, was the first to note that only rockets could serve the needs of space travel. In 1923, Herman Oberth published a treatise discussing various aspects of interplanetary travel including the impulse necessary to escape the Earth's gravitational pull. In his spare time, a German civil engineer, Walter Hohmann, established in 1925 that the optimal energy transfer orbit between planets is an ellipse that is tangent to the orbits of both bodies. Four year later, an Austrian army officer, Hermann Potocnik outlined the benefits of space stations including those in geosynchronous orbits. Whereas Tsiolkovsky, Oberth, Hohmann, and Potocnik provided ideas and theories, the American, Robert H. Goddard, was testing liquid fueled rockets by as early as 1925. By the time he was finished in 1941, Goddard flew liquid fueled rockets that reached speeds of 700 mph and altitudes above 8,000 feet. In direct contrast to the advances by these mostly amateur engineers, many respected authorities scoffed at space travel because of the insurmountable technological difficulties. One year prior to the launch of Sputnik, the British Astronomer Royal, Sir Richard Wooley, declared, "space travel is utter bilge." While the theories of space travel were well developed by the late 1920's, space travel technology was still a poorly funded, mostly amateur, endeavor until the German army hired Oberth's student, Werner von Braun, and others to develop long range rockets for military purposes. In the early 1940's, Von Braun's team developed the rocket propulsion and guidance systems that would one day form the basis of the American space program.

Wernher von Braun

NASA Image and Video Library

1968-07-31

Ground breaking ceremony for the Alabama Space Science Center, later renamed the U.S. Space and Rocket Center. Shown in this picture, left to right, are Edward O. Buckbee, Space Center Director; Jack Giles, Alabama State Senator of Huntsville; Dr. Wernher on Braun, Marshall Space Flight Center (MSFC) Director; Martin Darity, head of the Alabama Publicity Bureau (representing Governor Albert Brewer); James Allen, former Lieutenant governor, chairman of the Alabama Space Science Exhibit Commission; Major General Charles Eifler, commanding general of the Army Ordnance Missile Command; and Huntsville Mayor Glenrn Hearn. (Courtesy of Huntsville/Madison County Public Library)

100 Years Werner Heisenberg: Works and Impact

NASA Astrophysics Data System (ADS)

Papenfuß, Dietrich; Lüst, Dieter; Schleich, Wolfgang P.

2003-09-01

Over 40 renowned scientists from all around the world discuss the work and influence of Werner Heisenberg. The papers result from the symposium held by the Alexander von Humboldt-Stiftung on the occasion of the 100th anniversary of Heisenberg's birth, one of the most important physicists of the 20th century and cofounder of modern-day quantum mechanics. Taking atomic and laser physics as their starting point, the scientists illustrate the impact of Heisenberg's theories on astroparticle physics, high-energy physics and string theory right up to processing quantum information.

Around Marshall

NASA Image and Video Library

1999-07-17

A fountain representing a rocket launch was dedicated in the Von Braun courtyard outside of Building 4200 at Marshall Space Flight Center during the weekend celebrating the 30th arniversary of the Apollo 11 lunar landing. On hand for the festivities were many of the Saturn and Apollo astronauts.

Around Marshall

NASA Image and Video Library

1968-02-22

During a visit to the Marshall Space Flight Center (MSFC), the Congressional House Committee on Science and Astronautics toured the S-IVB workshop. Pictured here are MSFC’s Dr. Wernher von Braun (standing) and Congressman Miller, Democratic representative of California (sitting on the ergometer bicycle) inside the workshop.

Werner-Syndrom. Eine prototypische Form der segmentalen Progerie

PubMed Central

Lessel, D.; Oshima, J.; Kubisch, C.

2013-01-01

Das Werner-Syndrom ist eine segmental progeroide Erkrankung mit Beginn in der Adoleszenz oder im frühen Erwachsenenalter. Typische Symptome, die zum vorgealterten Phänotyp beitragen, sind ein post-pubertär auftretender Kleinwuchs, Katarakte, eine vorzeitige Ergrauung/Ausdünnung des Haupthaars, sklerodermieähnliche Hautveränderungen und eine regionale Atrophie des subkutanen Fettgewebes. Darüber hinaus kommt es früh und gehäuft zu „Alterserkrankungen“ wie z. B. einem Diabetes mellitus Typ 2, einer Osteoporose, einer Atherosklerose sowie verschiedenen malignen Tumoren. Das Werner-Syndrom wird autosomal- rezessiv vererbt und ist durch Mutationen im Werner-Gen (WRN) bedingt. Es wurden bis heute mehr als 70 über das gesamte Gen verteilte Mutationen identifiziert, die typischerweise zu einem Verlust der Genfunktion führen. WRN kodiert für eine RecQ-Typ- Helikase, die u. a. an der DNA-Reparatur und der Aufrechterhaltung der DNA-Integrität beteiligt ist, was sich in einer erhöhten genetischen Instabilität in Patientenzellen wider-spiegelt. Trotz der relativen Seltenheit ist die Analyse des Werner-Syndroms von allgemeiner Bedeutung, um die Rolle der DNA-Stabilität und Integrität für das Altern sowie die Entwicklung altersassoziierter Erkrankungen besser zu verstehen. PMID:25309043

Casting Footprints for Eternity

NASA Technical Reports Server (NTRS)

1999-01-01

Apollo 11 Astronaut Buzz Aldrin has his footprints casted during the dedication ceremony of the rocket fountain at Building 4200 at Marshall Space Flight Center. The casts of Aldrin's footprints will be placed in the newly constructed Von Braun courtyard representing the accomplishments of the Apollo 11 lunar landing.

n/a

NASA Image and Video Library

1953-08-20

The first Redstone was fired at Cape Canaveral, Florida on August 20, 1953. Redstone was the first major rocket development program for United States by the Peenemuende group led by Dr. Wernher von Braun. The Redstone launch photographed here, from November 17, 1954, was the fifth launch of a Redstone rocket.

Early Rockets

NASA Image and Video Library

1950-01-01

Test firing of a Redstone Missile at Redstone Test Stand in the early 1950's. The Redstone was a high-accuracy, liquid-propelled, surface-to-surface missile developed by the von Braun Team under the management of the U.S. Army. The Redstone was the first major rocket development program in the United States.

Members of House Committee on Science and Astronautics Visited MSFC

NASA Technical Reports Server (NTRS)

1962-01-01

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. The subcommittee was briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. In this photograph, MSFC Director, Dr. Wernher von Braun meets with Congressmen in the MSFC boardroom. Pictured from left to right are: Jack Cramer, NASA Headquarters; Joe Waggoner, Democratic representative of Louisiana; John W. Davis, Democratic representative of Georgia; R. Walter Riehlman, Republican representative of New York; Olin E. Teague, Democratic representative of Texas; Dr. Wernher von Braun, Director of MSFC; James G. Fulton, Republican representative of Pennsylvania; Ken Hechler, Democratic representative of West Virginia; and Erich Neubert of MSFC.

SAFE Testing Nuclear Rockets Economically

NASA Astrophysics Data System (ADS)

Howe, Steven D.; Travis, Bryan; Zerkle, David K.

2003-01-01

Several studies over the past few decades have recognized the need for advanced propulsion to explore the solar system. As early as the 1960s, Werner Von Braun and others recognized the need for a nuclear rocket for sending humans to Mars. The great distances, the intense radiation levels, and the physiological response to zero-gravity all supported the concept of using a nuclear rocket to decrease mission time. These same needs have been recognized in later studies, especially in the Space Exploration Initiative in 1989. One of the key questions that has arisen in later studies, however, is the ability to test a nuclear rocket engine in the current societal environment. Unlike the Rover/NERVA programs in the 1960s, the rocket exhaust can no longer be vented to the open atmosphere. As a consequence, previous studies have examined the feasibility of building a large-scale version of the Nuclear Furnace Scrubber that was demonstrated in 1971. We have investigated an alternative that would deposit the rocket exhaust along with any entrained fission products directly into the ground. The Subsurface Active Filtering of Exhaust, or SAFE, concept would allow variable sized engines to be tested for long times at a modest expense. A system overview, results of preliminary calculations, and cost estimates of proof of concept demonstrations are presented. The results indicate that a nuclear rocket could be tested at the Nevada Test Site for under $20 M.

Rocket center Peenemuende - Personal memories

NASA Technical Reports Server (NTRS)

Dannenberg, Konrad; Stuhlinger, Ernst

1993-01-01

A brief history of Peenemuende, the rocket center where Von Braun and his team developed the A-4 (V-2) rocket under German Army auspices, and the Air Force developed the V-1 (buzz bomb), wire-guided bombs, and rocket planes, is presented. Emphasis is placed on the expansion of operations beginning in 1942.

The First Robotics Rocket City Regional Competition

NASA Image and Video Library

2018-03-16

The First Robotics Rocket City Regional Competition was held at the Von Braun Civic Center in Huntsville, Alabama on March 16, 2018. High school robotics teams from throughout the U.S., as well as a team from Brazil, competed. Costumed students were the normal at this event and lent it much color.

Mercury Project

NASA Image and Video Library

1961-03-24

The Mercury-Redstone Booster Development vehicle (MR-BD) lifts off from Cape Canaveral March 24, 1961. This test flight evaluated changes incorporated in the booster designed to reduce vehicle oscillations and vibrations. The Mercury-Redstone launch vehicle was developed by Dr. Wernher von Braun and the rocket team in Huntsville, Alabama.

The Team From Brazil at the First Robotics Rocket City Regional

NASA Image and Video Library

2018-03-16

The First Robotics Rocket City Regional Competition was held at the Von Braun Civic Center in Huntsville, Alabama on March 16, 2018. High school robotics teams from throughout the U.S., as well as a team from Brazil, competed. The Brazilian team sings their national anthem.

The Team From Brazil at the First Robotics Rocket City Regional

NASA Image and Video Library

2018-03-16

The First Robotics Rocket City Regional Competition was held at the Von Braun Civic Center in Huntsville, Alabama on March 16, 2018. High school robotics teams from throughout the U.S., as well as a team from Brazil, competed. Pictured is the Brazilian team prior to competition

Origin of Marshall Space Flight Center (MSFC)

NASA Image and Video Library

1940-01-01

The German Rocket Team, also known as the Von Braun Rocket Team, poses for a group photograph at Fort Bliss, Texas. After World War II ended in 1945, Dr. Wernher von Braun led some 120 of his Peenemuende Colleagues, who developed the V-2 rocket for the German military during the War, to the United Sttes under a contract to the U.S. Army Corps as part of Operation Paperclip. During the following five years the team worked on high altitude firings of the captured V-2 rockets at the White Sands Missile Range in New Mexico, and a guided missile development unit at Fort Bliss, Texas. In April 1950, the group was transferred to the Army Ballistic Missile Agency (ABMA) at Redstone Arsenal in Huntsville, Alabama, and continued to work on the development of the guided missiles for the U.S. Army until transferring to a newly established field center of the National Aeronautic and Space Administration (NASA), George C. Marshall Space Flight Center (MSFC).

Walt Disney visited Marshall Space Flight Center (MSFC)

NASA Technical Reports Server (NTRS)

1965-01-01

Walt Disney toured the West Test Area during his visit to the Marshall Space Flight Center on April 13, 1965. The three in center foreground are Karl Heimburg, Director, Test Division; Dr. von Braun, Director, MSFC; and Walt Disney. The Dynamic Test Stand with the S-1C stage being installed is in the background.

Ley, Willy (1906-69)

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

Rocket scientist, writer, born in Berlin, Germany. Inspired by reading a work by the space pioneer, HERMANN OBERTH, Ley founded the German Society for Space Travel (1927), enrolled WERNHER VON BRAUN, and helped develop the liquid-fuel rocket. Fled to the USA, and became a science writer, including science fiction and film scripts....

50 Years of Electronic Check Out and Launch Systems at Kennedy Space Center

NASA Technical Reports Server (NTRS)

Starr, Stanley O.

2007-01-01

When NASA was created in 1958 one of the elements incorporated into this new agency was the Army Ballistic Missile Agency (ABMA) in Huntsville, AL and its subordinate Missile Firing Laboratory (MFL) in Cape Canaveral. Under NASA, the MFL became the Launch Operations Directorate of the George C. Marshall Space Flight Center in Huntsville, but expanding operations in the build up to Apollo dictated that it be given the status of a full fledged Center in July, 1 962[ 1]. The next year it was renamed the John F. Kennedy Space Center (KS C) after the president whose vision transformed its first decade of operation. The ABMA was under the technical leadership of Dr. Werner Von Braun. The MEL was run by his deputy Dr. Kurt Debus, an electrical engineer whose experience in the field began in the early days of V-2 testing in war time Germany. In 1952 a group led by Debus arrived in Cape Canaveral to begin test launches of the new Redstone missile [2]. During the 50's, The MFL built several launch complexes and tested the Redstone, Jupiter and Jupiter C missiles. This small experienced team of engineers and technicians formed the seed from which has grown the KSC team of today. This article briefly reviews the evolution of the KSC electronic technologies for integration, check-out and launch of space vehicles and payloads during NASA's first 50 years.

10th Annual Dr. Wernher von Braun Memorial Symposium

NASA Image and Video Library

2017-10-26

Acting NASA Administrator Robert Lightfoot, in his luncheon speech at the symposium Oct. 26, spoke about the newly reestablished National Space Council chaired by Vice President Mike Pence and NASA’s directive to develop a plan for an innovative and sustainable program of exploration with commercial and international partners to enable human expansion across the solar system

20. HISTORIC VIEW OF THE VEREIN FUER RAUMSCHIFFAHRT, 1930. LEFT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. HISTORIC VIEW OF THE VEREIN FUER RAUMSCHIFFAHRT, 1930. LEFT TO RIGHT: RUDOLF NEBEL, FRANZ RITTER, UNKNOWN, KURT HEINISCH, UNKNOWN, HERMANN OBERTH, UNKNOWN, KLAUS RIEDEL, WERNHER VON BRAUN, UNKNOWN, KLAUS RIEDEL HOLDS EARLY VERSION OR MODEL FOR THE MINIMUM ROCKET, 'MIRAK'. - Marshall Space Flight Center, Redstone Rocket (Missile) Test Stand, Dodd Road, Huntsville, Madison County, AL

n/a

NASA Image and Video Library

1971-07-26

During the Apollo 15 pre-launch activity in the launch control center's firing room 1 at Kennedy Space Center, the then recently appointed NASA Administrator, Dr. James C. Fletcher (right) speaks with (Left to right) William Anders, executive secretary of the National Aeronautics and Space Council; Lt. General Sam Phillips, former Apollo Program Director; and Dr. Wernher von Braun, NASA's Deputy Associate Administrator for planning.

Oberth, Hermann (1894-1989)

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

German space travel visionary, born in Sibiu, Hungary. His book Die Rakete zu den Planetenrämen (The Rocket into Interplanetary Space), established his reputation in 1923, and he became president of the German Society for Space Travel. In the Second World War he worked on rockets at Peenemünde, and went with WERNHER VON BRAUN to the US Army Ballistic Missile Agency in Huntsville, Alabama to devel...

Five Pioneers with Scale Models of Their Missiles

NASA Technical Reports Server (NTRS)

1950-01-01

Five pioneers pose with scale models of their missiles they created in the 1950s. From left to right: Dr. Ernst Stuhlinger, a member of the original German rocket team who directed the Research Projects Office, Army Ballistic Missile Agency (ABMA); Major General Holger Toftoy, who consolidated U.S. missile and rocketry development; Professor Herman Oberth, a rocket pioneer and Dr. von Braun's mentor; Dr. Wernher von Braun, Director, Development Operation Division, ABMA; and Dr. Robert Lusser, who served as assistant director for Reliability Engineering for ABMA. This photographis was taken February 1, 1956 by Hank Walker and appeared in February 27, 1956 issue of Life magazine.

Early Rockets

NASA Image and Video Library

1953-08-30

U.S. Army Redstone Rocket: The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by the Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone rocket was also known as "Old Reliable" because of its many diverse missions. The first Redstone Missile was launched from Cape Canaveral, Florida on August 30, 1953.

Physicists and Physics in Munich

NASA Astrophysics Data System (ADS)

Teichmann, Jürgen; Eckert, Michael; Wolff, Stefan

We give a tour of Munich and some outlying sites that focuses on the lives and work of the most prominent physicists who lived in the city, Count Rumford, Joseph Fraunhofer, Georg Simon Ohm, Max Planck, Ludwig Boltzmann, Albert Einstein, Wilhelm Conrad Röntgen, Wilhelm Wien, Arnold Sommerfeld, Max von Laue, and Werner Heisenberg. We close with a self-guided tour that describes how to reach these sites in Munich.

Braun, Wernher von (1912-77)

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

Rocket scientist, born in Wirsitz, Germany, enthusiast of space travel from an early age, designer of the V-2 rocket used during the second World War. With 120 associates from Peenemunde, went to the United States and directed firings of captured V-2 rockets at White Sands Missile Range in New Mexico, following which he used a Jupiter-C (Juno I) to put America's first satellite, Explorer 1, into ...

Around Marshall

NASA Image and Video Library

1999-07-17

Outside of Building 4200 at Marshall Space Flight Center, a courtyard was constructed in memory of Dr. Wernher von Braun and his contributions to the U. S. Space program. In the middle of the courtyard a fountain was built. The fountain was made operational prior to the 30th arniversary celebration of the Apollo 11 lunar landing. Attending the dedication ceremony were visiting Apollo astronauts and NASA's Safety and Assurance Director Rothenberg.

Fountain Dedication

NASA Technical Reports Server (NTRS)

1999-01-01

Outside of Building 4200 at Marshall Space Flight Center, a courtyard was constructed in memory of Dr. Wernher von Braun and his contributions to the U. S. Space program. In the middle of the courtyard a fountain was built. The fountain was made operational prior to the 30th arniversary celebration of the Apollo 11 lunar landing. Attending the dedication ceremony were visiting Apollo astronauts and NASA's Safety and Assurance Director Rothenberg.

Mercury Project

NASA Image and Video Library

1961-05-05

Dr. von Braun addresses a crowd celebrating in front of the Madison County Alabama Courthouse following the successful launch of Astronaut Alan Shepard (America's first astronaut in space) into space on a Mercury-Redstone Launch Vehicle, Freedom 7. Shepard's Mercury Spacecraft, was launched from Cape Canaveral. He reached a speed of 5200 mph. His flight lasted 15-1/2 minutes. May 5, 1961 (Photo: Courtesy of Huntsville/Madison County Public Library)

Mercury Project

NASA Image and Video Library

1961-01-01

Ham, a three-year-old chimpanzee, in the spacesuit he would wear for the second Mercury- Redstone (MR-2) suborbital test flight in January, 1961. NASA used chimpanzees and other primates to test the Mercury capsule before launching the fisrt American astronaut, Alan Shepard, in May 1961. The Mercury capsule rode atop a modified Redstone rocket, developed by Dr. Wernher von Braun and the German Rocket Team in Huntsville, Alabama.

Origin of Marshall Space Flight Center (MSFC)

NASA Image and Video Library

1950-01-01

Five pioneers pose with scale models of their missiles they created in the 1950s. From left to right: Dr. Ernst Stuhlinger, a member of the original German rocket team who directed the Research Projects Office, Army Ballistic Missile Agency (ABMA); Major General Holger Toftoy, who consolidated U.S. missile and rocketry development; Professor Herman Oberth, a rocket pioneer and Dr. von Braun's mentor; Dr. Wernher von Braun, Director, Development Operation Division, ABMA; and Dr. Robert Lusser, who served as assistant director for Reliability Engineering for ABMA. This photographis was taken February 1, 1956 by Hank Walker and appeared in February 27, 1956 issue of Life magazine.

High-Pressure Systems Suppress Fires in Seconds

NASA Technical Reports Server (NTRS)

2012-01-01

Much deserved attention is given to the feats of innovation that allow humans to live in space and robotic explorers to beam never-before-seen images back to Earth. In the background of these accomplishments is a technology that makes it all possible the rockets that propel NASA s space exploration efforts skyward. Marshall Space Flight Center has been at the heart of the Agency s rocketry and spacecraft propulsion efforts since its founding in 1960. Located at the Redstone Arsenal near Huntsville, Alabama, the Center has a legacy of success stretching back to the Saturn rockets that carried the Apollo astronauts into space. Even before Marshall was established, Redstone was the site of significant advances in American rocketry under the guidance of famous rocket engineer Werner Von Braun; these included the Juno I rocket that successfully carried the United States first satellite, Explorer 1, into orbit in 1958. And from the first orbital test flight of the Space Shuttle Columbia through the final flights of the shuttle program this year, these vehicles have been enabled by the solid rocket boosters, external tank, and orbiter main engines created at Marshall. Today, Marshall continues to host innovation in rocket and spacecraft propulsion at state-of-the-art facilities such as the Propulsion Research Laboratory. Like many of its past successes, some of the Center s current advancements are being made with the help of private industry partners. The efforts have led not only to new propulsion technologies, but to terrestrial benefits in a seemingly unrelated field in this case, firefighting.

Around Marshall

NASA Image and Video Library

1964-04-28

Two US Congressmen, accompanied by NASA Administrator James E. Webb, visited the Marshall Space Flight Center (MSFC) April 28, 1964, for a briefing on the Saturn program and a tour of the facilities. They are (left to right) Congressman Gerald Ford Jr., Republican representative of Michigan; Dr. Wernher von Braun, MSFC director; Congressman George H. Mahon, Democratic representative of Texas; and Mr. Webb. Not pictured is Dr. Robert Seamans, associate administrator, who was also in the group.

Visiting Author

NASA Technical Reports Server (NTRS)

1999-01-01

Author of Rocket Boys Homer Hickam, Jr. (left) and Marshall Space Flight Center Director Art Stephenson during a conference at Morris Auditorium. Homer Hickam worked at MSFC during the Apollo project years. As a young man, Mr. Hickam always dreamed of becoming a rocket scientist and following in the footsteps fo Wernher von Braun. Years later he would see his dream realized and had written Rocket Boys commemorating his life and the people at MSFC.

Space Station Freedom Utilization Conference: Executive summary

NASA Technical Reports Server (NTRS)

1992-01-01

From August 3-6, 1992, Space Station Freedom Program (SSFP) representatives and prospective Space Station Freedom researchers gathered at the Von Braun Civic Center in Huntsville, Alabama, for NASA's first annual Space Station Freedom (SSF) Utilization Conference. The sessions presented are: (1) overview and research capabilities; (2) research plans and opportunities; (3) life sciences research; (4) technology research; (4) microgravity research and biotechnology; and (5) closing plenary.

Origin of Marshall Space Flight Center (MSFC)

NASA Image and Video Library

1950-01-01

As the nations missile and rocket program began to expand in the 50's, Huntsville, Alabama was the home to Redstone Arsenal and the famous team of rocket experts led by Dr. Wernher Von Braun. Soon Huntsville was called the "Rocket City" as depicted in this photo believed to have been taken in the 1950's in Huntsville, Alabama. (Courtesy of Huntsville/Madison County Public Library)

Ham in Spacesuit

NASA Technical Reports Server (NTRS)

1961-01-01

Ham, a three-year-old chimpanzee, in the spacesuit he would wear for the second Mercury- Redstone (MR-2) suborbital test flight in January, 1961. NASA used chimpanzees and other primates to test the Mercury capsule before launching the fisrt American astronaut, Alan Shepard, in May 1961. The Mercury capsule rode atop a modified Redstone rocket, developed by Dr. Wernher von Braun and the German Rocket Team in Huntsville, Alabama.

Early Rockets

NASA Image and Video Library

1940-01-01

The cutaway drawing of the A-4 (Aggregate-4) rocket. Later renamed the V-2 (Vengeance Weapon-2), The rocket was developed by Dr. Wernher von Braun and the German rocket team at Peenemuende, Germany on the Baltic Sea. At the end of World War II, the team of German engineers and scientists came to the United States and continued rocket research for the Army at Fort Bliss, Texas, and Redstone Arsenal in Huntsville, Alabama.

Early Rockets

NASA Image and Video Library

1940-01-01

This drawing illustrates the vital dimensions of the A-4 (Aggregate-4). Later renamed the V-2 (Vengeance Weapon-2), the rocket was developed by Dr. Wernher von Braun and the German rocket team at Peenemuende, Germany on the Baltic Sea. At the end of World War II, the team of German engineers and scientists came to the United States and continued rocket research for the Army at Fort Bliss, Texas, and Redstone Arsenal in Huntsville, Alabama.

Around Marshall

NASA Image and Video Library

1999-07-16

Author of Rocket Boys Homer Hickam, Jr. (left) and Marshall Space Flight Center Director Art Stephenson during a conference at Morris Auditorium. Homer Hickam worked at MSFC during the Apollo project years. As a young man, Mr. Hickam always dreamed of becoming a rocket scientist and following in the footsteps fo Wernher von Braun. Years later he would see his dream realized and had written Rocket Boys commemorating his life and the people at MSFC.

[The "utopian" national socialism - a mutual dispute in the philosophy of Martin Heidegger and Carl Friedrich von Weizsäcker?].

PubMed

Schäfer, Wolf

2014-01-01

In a letter to his wife from October 14, 1943, Werner Heisenberg describes a fierce clash with Carl Friedrich von Weizsäcker. The sudden conflict raises numerous questions, two of which are tackled here. First: How is now the friendly relationship between Heisenberg and Weizsäcker in the postwar years to be understood? The answer is: as a strategic performance. Second: How are the radical opinions to be explained that Weizsäcker expressed at the time? A thorough reconstruction of the lifelong connection that Weizsäcker maintained with Martin Heidegger and Heidegger's philosophy gives the answer: the young Weizsäcker was fired up by the "utopian" National Socialism with which Heidegger trumped the real existing.

Origin of Marshall Space Flight Center (MSFC)

NASA Image and Video Library

1959-08-11

In this picture, negotiations are under way between officials of the Army Ballistic Missile Agency (ABMA) and the National Aeronautics and Space Administration (NASA) on August 11, 1959. Seated at the table with his back to the camera, is Dr. T. Keith Glernan, NASA Administrator. At the head of the table is Major General John Barclay, Commander of ABMA and at the right side of the table are Colonel John G. Zierdt of ABMA and Dr. von Braun.

Early Rockets

NASA Image and Video Library

1940-01-01

This German cutaway drawing of the Aggregate-4 (A-4) illustrates the dimensions and internal workings of the rocket. Later renamed the V-2, the rocket was developed by Dr. Wernher von Braun and the German Rocket Team at Peenemuende on the Baltic Sea. At the end of World War II, the team of German engineers and scientists came to the United States to work for the Army at Fort Bliss, Texas, and Redstone Arsenal in Huntsville, Alabama.

Negotiations Between ABMA Officials and NASA Officials

NASA Technical Reports Server (NTRS)

1959-01-01

In this picture, negotiations are under way between officials of the Army Ballistic Missile Agency (ABMA) and the National Aeronautics and Space Administration (NASA) on August 11, 1959. Seated at the table with his back to the camera, is Dr. T. Keith Glernan, NASA Administrator. At the head of the table is Major General John Barclay, Commander of ABMA and at the right side of the table are Colonel John G. Zierdt of ABMA and Dr. von Braun.

Into the Unknown Together. The DOD, NASA, and Early Spaceflight

DTIC Science & Technology

2005-09-01

achieve greater independence by lessening its reliance on the DOD over these 12 years? Equally important to the NASA- DOD relationship was the...first annual report. That 1948 report stated, “The Earth Satellite Vehicle Program, which was being carried out independently by each military service...Wernher von Braun did muse, “Suppose a National Space Agency were set up, either under the Secretary of Defense or as an independent agency, and this agency

Wernher von Braun

NASA Image and Video Library

1969-07-01

This photograph depicts Dr. von Braun (fourth from far right) and other NASA officials surveying the deep-sea research submarine "Ben Franklin." Named for American patriot and inventor Ben Franklin, who discovered the Gulf Steam, the 50-foot Ben Franklin was built between 1966 and 1968 in Switzerland for deep-ocean explorer Jacques Piccard and the Grumman Aircraft Engineering Corporation. The submersible made a famous 30-day drift dive off the East Coast of the United States and Canada in 1969 mapping the Gulf Stream's currents and sea life, and also made space exploration history by studying the behavior of aquanauts in a sealed, self-contained, self-sufficient capsule for NASA. On July 14, 1969, the Ben Franklin was towed to the high-velocity center of the Stream off the coast of Palm Beach, Florida. With a NASA observer on board, the sub descended to 1,000 feet off of Riviera Beach, Florida and drifted 1,400 miles north with the current for more than four weeks, reemerging near Maine. During the course of the dive, NASA conducted exhaustive analyses of virtually every aspect of onboard life. They measured sleep quality and patterns, sense of humor and behavioral shifts, physical reflexes, and the effects of a long-term routine on the crew. The submarine's record-shattering dive influenced the design of Apollo and Skylab missions and continued to guide NASA scientists as they devised future marned space-flight missions.

Wernher von Braun

NASA Image and Video Library

1969-07-01

This photograph depicts Dr. von Braun (at right, showing his back) and other NASA officials surveying the deep-sea research submarine "Ben Franklin." Named for American patriot and inventor Ben Franklin, who discovered the Gulf Steam, the 50-foot Ben Franklin was built between 1966 and 1968 in Switzerland for deep-ocean explorer Jacques Piccard and the Grumman Aircraft Engineering Corporation. The submersible made a famous 30-day drift dive off the East Coast of the United States and Canada in 1969 mapping the Gulf Stream's currents and sea life, and also made space exploration history by studying the behavior of aquanauts in a sealed, self-contained, self-sufficient capsule for NASA. On July 14, 1969, the Ben Franklin was towed to the high-velocity center of the Stream off the coast of Palm Beach, Florida. With a NASA observer on board, the sub descended to 1,000 feet off of Riviera Beach, Florida and drifted 1,400 miles north with the current for more than four weeks, reemerging near Maine. During the course of the dive, NASA conducted exhaustive analyses of virtually every aspect of onboard life. They measured sleep quality and patterns, sense of humor and behavioral shifts, physical reflexes, and the effects of a long-term routine on the crew. The submarine's record-shattering dive influenced the design of Apollo and Skylab missions and continued to guide NASA scientists as they devised future marned space-flight missions.

KSC-2012-1850

NASA Image and Video Library

2012-02-17

Dr. Kurt H. Debus, Kennedy Space Center's First Director: A doctor of philosophy in engineering from Darmstadt University, Debus was selected by Dr. Wernher von Braun to direct the Experimental Missile Firing Branch which began launching missiles from Cape Canaveral in 1953. Dr. Debus became the first Center Director for the new independent Launch Operations Center, and it was his job to put Saturn/Apollo into space. His tenure at Kennedy Space Center spanned 13 years, from 1962 to 1974. Poster designed by Kennedy Space Center Graphics Department/Greg Lee. Credit: NASA

The cosmic Era and the Earth

NASA Astrophysics Data System (ADS)

Closca-Grigore, Carmen

THe book describes the main directions of development of cosmic research in the USA, USSR, Europe, Japan and China. The main inventors and creators of cosmic technics are designed : Tsiolkovskii, Tsander, Korolev, Oberth, Verner von Braun, Goddard and the most important cosmic flies by Sputnik, Gagarin, Tereshkova, Leonov, Armstrong. The main program of cosmic research are outlined in such areas as maps, geological research, meteorolgy, television, radio and military. The Romanian contributions are described: Ioan Vitez, Konrad Haas, Traian Vuia, Aurel Vlaicu, Hermann Oberth and Dumnitru Prunariu.

Dr. von Braun on top of the Deep-Sea Research Submarine 'Ben Franklin'

NASA Technical Reports Server (NTRS)

1969-01-01

This photograph depicts Dr. von Braun (at right, showing his back) and other NASA officials surveying the deep-sea research submarine 'Ben Franklin.' Named for American patriot and inventor Ben Franklin, who discovered the Gulf Steam, the 50-foot Ben Franklin was built between 1966 and 1968 in Switzerland for deep-ocean explorer Jacques Piccard and the Grumman Aircraft Engineering Corporation. The submersible made a famous 30-day drift dive off the East Coast of the United States and Canada in 1969 mapping the Gulf Stream's currents and sea life, and also made space exploration history by studying the behavior of aquanauts in a sealed, self-contained, self-sufficient capsule for NASA. On July 14, 1969, the Ben Franklin was towed to the high-velocity center of the Stream off the coast of Palm Beach, Florida. With a NASA observer on board, the sub descended to 1,000 feet off of Riviera Beach, Florida and drifted 1,400 miles north with the current for more than four weeks, reemerging near Maine. During the course of the dive, NASA conducted exhaustive analyses of virtually every aspect of onboard life. They measured sleep quality and patterns, sense of humor and behavioral shifts, physical reflexes, and the effects of a long-term routine on the crew. The submarine's record-shattering dive influenced the design of Apollo and Skylab missions and continued to guide NASA scientists as they devised future marned space-flight missions.

Jen Gustetic visits Swamp Works

NASA Image and Video Library

2016-10-28

Jenn Gustetic, NASA's Small Business Innovation Research Program executive, talks with Rob Mueller, senior technologist and co-founder of Kennedy Space Center's Swamp Works. Gustetic met team members and viewed many of the pioneering technologies and innovations in development at Kennedy. Swamp Works is a hands-on, lean development environment for innovation following the philosophies pioneered in Kelly Johnson's Skunk Works and Werner von Braun's development shops. The Swamp Works establishes rapid, innovative and cost-effective exploration mission solutions through a highly collaborative, "no walls" approach, leveraging partnerships across NASA, industry and academia.

Around Marshall

NASA Image and Video Library

1999-07-17

A replica of the Saturn V rocket that propelled man from the confines of Earth's gravity to the surface of the Moon was built on the grounds of the U. S. Space and Rocket Center in Huntsville, AL. in time for the 30th arniversary celebration of that historic occasion. Marshall Space Flight Center and its team of German rocket scientists headed by Dr. Wernher von Braun were responsible for the design and development of the Saturn V rocket. Pictured are MSFC's current Center Director Art Stephenson, Alabama Congressman Bud Cramer, and NASA Administrator Dan Goldin during the dedication ceremony.

Saturn Apollo Program

NASA Image and Video Library

1950-01-01

This historical photograph is of the Apollo Space Program Leaders. An inscription appears at the top of the image that states, “Our deep appreciation for your outstanding contribution to the success of Apollo 11”, signed “S”, indicating that it was originally signed by Apollo Program Director General Sam Phillips, pictured second from left. From left to right are; NASA Associate Administrator George Mueller; Phillips; Kurt Debus, Director of the Kennedy Space Center; Robert Gilruth, Director of the Manned Spacecraft Center, later renamed the Johnson Space Center; and Wernher von Braun, Director of the Marshall Space Flight Center.

A Dermatologist's Ammunition in the War Against Smoking: A Photoaging App.

PubMed

Brinker, Titus Josef; Enk, Alexander; Gatzka, Martina; Nakamura, Yasuhiro; Sondermann, Wiebke; Omlor, Albert Joachim; Petri, Maximilian Philip; Karoglan, Ante; Seeger, Werner; Klode, Joachim; von Kalle, Christof; Schadendorf, Dirk

2017-09-21

This viewpoint reviews the perspectives for dermatology as a specialty to go beyond the substantial impact of smoking on skin disease and leverage the impact of skin changes on a person's self-concept and behavior in the design of effective interventions for smoking prevention and cessation. ©Titus Josef Brinker, Alexander Enk, Martina Gatzka, Yasuhiro Nakamura, Wiebke Sondermann, Albert Joachim Omlor, Maximilian Philip Petri, Ante Karoglan, Werner Seeger, Joachim Klode, Christof von Kalle, Dirk Schadendorf. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.09.2017.

Dr. von Braun on Top of the Deep-Sea Research Submarine 'Ben Franklin'

NASA Technical Reports Server (NTRS)

1969-01-01

This photograph depicts Dr. von Braun (fourth from far right) and other NASA officials surveying the deep-sea research submarine 'Ben Franklin.' Named for American patriot and inventor Ben Franklin, who discovered the Gulf Steam, the 50-foot Ben Franklin was built between 1966 and 1968 in Switzerland for deep-ocean explorer Jacques Piccard and the Grumman Aircraft Engineering Corporation. The submersible made a famous 30-day drift dive off the East Coast of the United States and Canada in 1969 mapping the Gulf Stream's currents and sea life, and also made space exploration history by studying the behavior of aquanauts in a sealed, self-contained, self-sufficient capsule for NASA. On July 14, 1969, the Ben Franklin was towed to the high-velocity center of the Stream off the coast of Palm Beach, Florida. With a NASA observer on board, the sub descended to 1,000 feet off of Riviera Beach, Florida and drifted 1,400 miles north with the current for more than four weeks, reemerging near Maine. During the course of the dive, NASA conducted exhaustive analyses of virtually every aspect of onboard life. They measured sleep quality and patterns, sense of humor and behavioral shifts, physical reflexes, and the effects of a long-term routine on the crew. The submarine's record-shattering dive influenced the design of Apollo and Skylab missions and continued to guide NASA scientists as they devised future marned space-flight missions.

Saturn V Dedication

NASA Technical Reports Server (NTRS)

1999-01-01

A replica of the Saturn V rocket that propelled man from the confines of Earth's gravity to the surface of the Moon was built on the grounds of the U. S. Space and Rocket Center in Huntsville, AL. in time for the 30th arniversary celebration of that historic occasion. Marshall Space Flight Center and its team of German rocket scientists headed by Dr. Wernher von Braun were responsible for the design and development of the Saturn V rocket. Pictured are MSFC's current Center Director Art Stephenson, Alabama Congressman Bud Cramer, and NASA Administrator Dan Goldin during the dedication ceremony.

Apollo Program Leadership

NASA Technical Reports Server (NTRS)

1950-01-01

This historical photograph is of the Apollo Space Program Leaders. An inscription appears at the top of the image that states, 'Our deep appreciation for your outstanding contribution to the success of Apollo 11', signed 'S', indicating that it was originally signed by Apollo Program Director General Sam Phillips, pictured second from left. From left to right are; NASA Associate Administrator George Mueller; Phillips; Kurt Debus, Director of the Kennedy Space Center; Robert Gilruth, Director of the Manned Spacecraft Center, later renamed the Johnson Space Center; and Wernher von Braun, Director of the Marshall Space Flight Center.

Asymmetric Synthesis of All the Known Phlegmarine Alkaloids

PubMed Central

Wolfe, Bradley H.; Libby, Adam H.; Al-awar, Rima S.; Foti, Christopher J.; Comins, Daniel L.

2010-01-01

The asymmetric synthesis of all four of the known natural phlegmarines and one synthetic derivative has been accomplished in 19 to 22 steps from 4-methoxy-3-(triisopropylsilyl)pyridine. Chiral N-acylpyridinium salt chemistry was used twice to set the stereocenters at the C-9 and C-2′ positions of the phlegmarine skeleton. Key reactions include the use of a mixed Grignard reagent for the second N-acylpyridinium salt addition, zinc/acetic acid reduction of a complex dihydropyridone, and a von Braun cyanogen bromide N-demethylation of a late intermediate. These syntheses confirmed the absolute stereochemistry of all the known phlegmarines. PMID:21077636

Around Marshall

NASA Image and Video Library

1962-03-08

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation’s space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. The subcommittee was briefed on MSFC’s manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. In this photograph, MSFC Director, Dr. Wernher von Braun and Joe Waggoner, Democratic representative of Louisiana, discuss Apollo models.

Saturn Apollo Program

NASA Image and Video Library

1971-01-01

This is a good cutaway diagram of the Saturn V launch vehicle showing the three stages, the instrument unit, and the Apollo spacecraft. The chart on the right presents the basic technical data in clear metric detail. The Saturn V is the largest and most powerful launch vehicle in the United States. The towering, 111 meter, Saturn V was a multistage, multiengine launch vehicle standing taller than the Statue of Liberty. Altogether, the Saturn V engines produced as much power as 85 Hoover Dams. Development of the Saturn V was the responsibility of the Marshall Space Flight Center at Huntsville, Alabama, directed by Dr. Wernher von Braun.

Members of House Committee on Science and Astronautics Visited MSFC

NASA Technical Reports Server (NTRS)

1962-01-01

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. The subcommittee was briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. In this photograph, MSFC Director, Dr. Wernher von Braun and Joe Waggoner, Democratic representative of Louisiana, discuss Apollo models.

About an Element of Human Greatness

NASA Technical Reports Server (NTRS)

Hickam, Homer

2005-01-01

One of the things Dr. von Braun instinctively knew was that it was as nearly important to explain why we should go into space as to build the machines to take us there. He wrote books and magazine articles, spoke to everyone he could formally and informally, and spent his life to his dying day seeking to educate everyone on the importance of and need for spaceflight. Why should we go? I think there are actually two principle reasons: 1) Because the solar system is filled with cheap, clean energy, and we need to go get it, and, 2) this one may well be even more important, because we need a purpose for ourselves and our country. I think we need an eternal frontier to push up against, our purpose to conquer and settle it. The nice thing about doing that is the solar system is a very rich place, filled with not only mineral wealth but energy, a nearly inexhaustible supply. And if there s one thing this country and this planet desperately needs and is willing to pay for now and forever is energy. The solar system is where it is. We've got to go after it. I believe, then, that Americans have both a self-interest and a patriotic duty to convince ourselves it is time to take another giant step into space. The way to do that is to do what Dr. von Braun did, cut metal and start flying. Success engenders success. Dr. von Braun s grand dream need never die. NASA can spark a twenty-first-century revolution in transportation and energy that could fundamentally change the way we fly through space, power the world, even care for the sick if we do it right. All those things require cheap and clean energy. It exists in the solar system in a variety of forms. Solar energy is the most obvious form, but there are others, including helium-3, which may be the perfect fuel for fusion reactors, and also just happens to cover the Moon. I believe we must go after it. We just need to believe in ourselves and our purpose. I call on all of you here today to join together, get things moving again, and get serious about conquering space. If we do, we'll assure the country s prosperity, and the world s survival, too, for centuries. Along the way, maybe we ll finally understand why my old preacher thought St. Peter s comment about looking for new heavens was so important. According to His promise, it s a big challenge, a huge responsibility, to try to fulfill such a promise and prophecy.

Climbing to stars

NASA Astrophysics Data System (ADS)

Maksimov, A. I.

2011-06-01

Development of cosmonautics and preparation to the first manned space flights are briefly observed. Details of the development of the first Soviet intercontinental ballistic missile R-7, which served as a basis for creating Sputnik, Vostok, Voskhod, Molniya, and Soyuz launchers, are given. The contributions of the outstanding designers of space engineering, W. von Braun, S.P. Korolev, V.P. Glushko, and academician M.V. Keldysh, to the development of astronautics and first manned space missions are demonstrated. A list of test launches and manned flights of Vostok and Mercury spacecrafts and the basic characteristics of Vostok, Redstone, Atlas-D, Voskhod, and Soyuz launchers are presented.

Around Marshall

NASA Image and Video Library

1962-03-08

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation’s space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. The subcommittee was briefed on MSFC’s manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. In this photograph, MSFC Director, Dr. Wernher von Braun, bids farewell to Texas Democratic Representative Olin E. Teague before departure at the Redstone Arsenal Airstrip.

Rocketry, film and fiction: the road to Sputnik

NASA Astrophysics Data System (ADS)

Brake, Mark; Hook, Neil

2007-07-01

The launch of Sputnik 1 in 1957 was fuelled by science fiction as well as science fact. The field of early rocketry included the work of Russians Nikolai Rynin and Konstantin Tsiolkovsky, American Robert Goddard, and German engineers Herman Oberth and Wernher Von Braun. All were directly inspired and influenced by early science fiction that heralded a space age decades ahead of time. The work of these pioneers led directly to the development of the technology needed to boost Sputnik skyward. After the launch of Sputnik, the context of the nuclear arms race opened the floodgates for a new wave of apocalyptic fiction.

Bernstein's failure to join the space race: his commentary on Tsiolkovskii's "Mechanics in Biology" (1964).

PubMed

Meijer, O G; Feigenberg, I M

2000-07-01

October 4, 1957, the Soviet Union launched Sputnik I into orbit from Tyuratam in Turkistan. An event "with the suddenness and surprise of a Pearl Harbor and of the impact of a Hiroshima atomic explosion" (Stoiko, 1970, p. ix). Nor would this be the only time America lost to the Russians in the space race. November 3 of the same year, Sputnik II carried the dog Laika, the first living being who traveled, and died, in space. In the USA, Senator Lyndon B. Johnson lamented: "Control of space means control of the world" (quoted from Heppenheimer, 1997, p. 126), and attempts were made to speed up Wernher von Braun's launching program (Piszkiewicz, 1995; cf. Von Braun, 1968). Alas, on December 6, when the American rocket began to lift, "it seemed as if the gates of hell had opened up. Brilliant stiletto flames shot out from the side of the rocket near the engine. The vehicle agonizingly hesitated for a moment, quivered again, and in front of our unbelieving, shocked eyes, began to topple" (Halberstam, quoted from Heppenheimer, p. 127). Thus, at the UN, "Soviet delegates asked their American counterparts if the United States might wish to receive foreign aid under Moscow's program of technical assistance to backwards nations" (from Heppenheimer, p. 128). Von Braun finally succeeded with the Explorer I on January 31, 1958, but for the Americans the agonizing wasn't over. On August 21, 1957, the Soviet Union launched an intercontinental ballistic missile (ICBM), this time carrying a dummy, but able to carry a nuclear bomb (Harford, 1997). So, the first ICBMs in the world were aimed at the USA. And then, on the morning of April 12, 1961, Yuri Gagarin shouted "Poyekhali" ("Let's go!") (quoted from Heppenheimer, p. 172), and was launched into space at 9:06 to fly "over America" 51 minutes later. Quite naturally, the Soviet authorities wanted to show that Russia had been ahead all the time, and historical heroes were in strong demand. The Russians didn't have to look far.

[Weizsäcker's cosmogony, Farm Hall and the origin of modern turbulence theory].

PubMed

Eckert, Michael

2014-01-01

The modem statistical theory of turbulence was originated by Andrey Nikolaevich Kolmogorov (1903-1987), Lars Onsager (1903-1976), Ludwig Prandtl (1875-1953), Werner Heisenberg (1901-1976) und Carl Friedrich von Weizsäcker (1912-2007). With the exception of Kolmogorovs theory which was published in 1941 but became widely known only after the war, these contributions emerged largely independently from another in a "remarkable series of coincidences" (Batchelor 1946). Heisenberg and Weizäscker developed their theories during their detention at Farm Hall. Their work was motivated by von Weizsäcker's interest in astrophysics. Weizsäcker aimed at an understanding of the role of turbulence for the motion of interstellar matter for his theory about the origin of the planetary system which he had published in 1943. Weizsäcker's work on cosmogony and turbulence illustrates an early interaction between the disciplines of astronomy and fluid mechanics that became characteristic for astrophysics in the second half of the twentieth century.

Diagram of Saturn V Launch Vehicle

NASA Technical Reports Server (NTRS)

1971-01-01

This is a good cutaway diagram of the Saturn V launch vehicle showing the three stages, the instrument unit, and the Apollo spacecraft. The chart on the right presents the basic technical data in clear detail. The Saturn V is the largest and most powerful launch vehicle in the United States. The towering 363-foot Saturn V was a multistage, multiengine launch vehicle standing taller than the Statue of Liberty. Altogether, the Saturn V engines produced as much power as 85 Hoover Dams. Development of the Saturn V was the responsibility of the Marshall Space Flight Center at Huntsville, Alabama, directed by Dr. Wernher von Braun.

Diagram of the Saturn V Launch Vehicle in Metric

NASA Technical Reports Server (NTRS)

1971-01-01

This is a good cutaway diagram of the Saturn V launch vehicle showing the three stages, the instrument unit, and the Apollo spacecraft. The chart on the right presents the basic technical data in clear metric detail. The Saturn V is the largest and most powerful launch vehicle in the United States. The towering, 111 meter, Saturn V was a multistage, multiengine launch vehicle standing taller than the Statue of Liberty. Altogether, the Saturn V engines produced as much power as 85 Hoover Dams. Development of the Saturn V was the responsibility of the Marshall Space Flight Center at Huntsville, Alabama, directed by Dr. Wernher von Braun.

Around Marshall

NASA Image and Video Library

1999-07-17

A replica of the Saturn V rocket that propelled man from the confines of Earth's gravity to the surface of the Moon was built on the grounds of the U. S. Space and Rocket Center in Huntsville, AL. in time for the 30th arniversary celebration of that historic occasion. Marshall Space Flight Center and its team of German rocket scientists headed by Dr. Wernher von Braun were responsible for the design and development of the Saturn V rocket. Pictured are MSFC's current Center Director Art Stephenson, Alabama Congressman Bud Cramer, NASA Administrator Dan Goldin, and director of the U. S. Space and Rocket Center Mike Wing during the dedication ceremony.

n/a

NASA Image and Video Library

1962-03-08

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. They were briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. Pictured left-to-right are Dieter Grau, MSFC; Konrad Dannenberg, MSFC; James G. Fulton, Republican representative for Pennsylvania; Joe Waggoner, Democratic representative for Louisiana; and Dr. Wernher von Braun, Director of MSFC.

Saturn V Dedication

NASA Technical Reports Server (NTRS)

1999-01-01

A replica of the Saturn V rocket that propelled man from the confines of Earth's gravity to the surface of the Moon was built on the grounds of the U. S. Space and Rocket Center in Huntsville, AL. in time for the 30th arniversary celebration of that historic occasion. Marshall Space Flight Center and its team of German rocket scientists headed by Dr. Wernher von Braun were responsible for the design and development of the Saturn V rocket. Pictured are MSFC's current Center Director Art Stephenson, Alabama Congressman Bud Cramer, NASA Administrator Dan Goldin, and director of the U. S. Space and Rocket Center Mike Wing during the dedication ceremony.

Members of House Committee on Science and Astronautics Visited MSFC

NASA Technical Reports Server (NTRS)

1962-01-01

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. The subcommittee was briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. In this photograph, MSFC Director, Dr. Wernher von Braun, bids farewell to Texas Democratic Representative Olin E. Teague before departure at the Redstone Arsenal Airstrip.

Members of House Committee on Science and Astronautics Visited MSFC

NASA Technical Reports Server (NTRS)

1962-01-01

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. The subcommittee was briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. In this photograph, MSFC Director, Dr. Wernher von Braun and Richard L. Roudebush, Republican representative of Indiana, discuss Apollo models.

Around Marshall

NASA Image and Video Library

1962-03-08

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation’s space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. Pictured from left-to-right are Congressman Ken Hechler, Democratic representative of West Virginia; Dieter Grau, MSFC; Congressman John W. Davis, Democratic representative of Georgia; Congressman Joe Waggoner, Democratic representative of Louisiana; Congressman Richard L. Roudebush, Republican representative of Indiana; Congressman R. Walter Riehlman, Republican representative of New York; Congressman James G. Fulton, Republican representative of Pennsylvania; Dr. Wernher von Braun, MSFC; and Congressman Olin E. Teague, Democratic representative of Texas.

The Saturn management concept

NASA Technical Reports Server (NTRS)

Bilstein, R. E.

1974-01-01

Management of the Saturn launch vehicles was an evolutionary process, requiring constant interaction between NASA Headquarters, the Marshall Space Flight Center (particularly the Saturn 5 Program Office), and the various prime contractors. Successful Saturn management was a blend of the decades of experience of the von Braun team, management concepts from the Army, Navy, Air Force, and Government, and private industry. The Saturn 5 Program Office shared a unique relationship with the Apollo Program Office at NASA Headquarters. Much of the success of the Saturn 5 Program Office was based on its painstaking attention to detail, emphasis on individual responsibilities (backed up by comprehensive program element plans and management matrices), and a high degree of visibility as embodied in the Program Control Center.

Collaborating with Planetaria to Improve Girl Scout's Appreciation of Astronomy

NASA Technical Reports Server (NTRS)

Adams, Mitzi; Phillips, Tony; Whitt, April

2003-01-01

We have collaborated with two planetaria, Fernbank Science Center's Jim Cherry planetarium in Atlanta, Georgia and the Von Braun Planetarium in Huntsville, Alabama to enhance the appreciation of various astronomical topics among Girl Scouts. Major events sponsored by our partnership were sleepovers in the planetaria during which we studied the total solar eclipse of June 2001 and observed the Eta Aquarid meteor shower of May 2003. Other events included programs on stellar spectroscopy and space physics. As an added inducement for participation, we have sponsored the production of "pins", which Girl Scouts can earn after satisfying specific requirements. This poster will show samples of the pins, requirements, and online resources for the Girl Scouts.

Members of House Committee on Science and Astronautics Visited MSFC

NASA Technical Reports Server (NTRS)

1962-01-01

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. They were briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. Pictured left-to-right are Dieter Grau, MSFC; Konrad Dannenberg, MSFC; James G. Fulton, Republican representative for Pennsylvania; Joe Waggoner, Democratic representative for Louisiana; and Dr. Wernher von Braun, Director of MSFC.

Enabling Exploration Missions Now: Applications of On-orbit Staging

NASA Technical Reports Server (NTRS)

Folta, David C.; Vaughn, Frank; Westmeyer, Paul; Rawitscher, Gary; Bordi, Francesco

2005-01-01

Future NASA Exploration goals are difficult to meet using current launch vehicle implementations and techniques. We introduce a concept of On-Orbit Staging (OOS) using multiple launches into a Low Earth orbit (LEO) staging area to increase payload mass and reduce overall cost for exploration initiative missions. This concept is a forward-looking implementation of ideas put forth by Oberth and Von Braun to address the total mission design. Applying staging throughout the mission and utilizing technological advances in propulsion efficiency and architecture enable us to show that exploration goals can be met in the next decade. As part of this architecture, we assume the readiness of automated rendezvous, docking, and assembly technology.

Members of House Committee on Science and Astronautics Visited MSFC

NASA Technical Reports Server (NTRS)

1962-01-01

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. Pictured from left-to-right are Congressman Ken Hechler, Democratic representative of West Virginia; Dieter Grau, MSFC; Congressman John W. Davis, Democratic representative of Georgia; Congressman Joe Waggoner, Democratic representative of Louisiana; Congressman Richard L. Roudebush, Republican representative of Indiana; Congressman R. Walter Riehlman, Republican representative of New York; Congressman James G. Fulton, Republican representative of Pennsylvania; Dr. Wernher von Braun, MSFC; and Congressman Olin E. Teague, Democratic representative of Texas.

VizieR Online Data Catalog: Calibrator stars catalog for interferometers (Swihart+, 2017)

NASA Astrophysics Data System (ADS)

Swihart, S. J.; Garcia, E. V.; Stassun, K. G.; van Belle, G.; Mutterspaugh, M. W.; Elias, N.

2017-04-01

In order to obtain accurate stellar angular sizes, each star was fit with a model SED using the fitting routine sedFit, written by A. Boden (van Belle & von Braun, 2009, Cat. J/ApJ/694/1085; van Belle et al. 2016, Cat. J/AJ/152/16). We compiled a list of positions, spectral types and visual magnitudes for ~3000 bright (Vmag<6) stars in the northern hemisphere with declinations -15°<δ<82° using the SIMBAD database (Wenger et al., 2000A&AS..143....9W). We chose a brightness limit (Vmag<6) given that most visible light interferometers can obtain scientifically useful data on bright stars. We also removed any stars which appear in the JMMC bad calibrator list. (4 data files).

Legal Implications of Military Uses of Outer Space

NASA Astrophysics Data System (ADS)

Catena, Johanna

2002-01-01

Acquisition of Space Weapons, the Legal, Political and Military Impact for International Peace and At the dawn of a new century an immediate danger is upon us: The weaponization of outer space, including potential cost implications upon the prospect of ushering an era of peace and prosperity. But, can such statements be explained as pure sentimentality for hopes of a new era? Or is the danger misplaced that the threat to peace and security is an ever more ominous? By militarising outer space one could monitor crisis areas that could become a potential threat and this would in turn build confidence and security amongst nations. However the Outer Space Treaty prohibits placing in orbit nuclear and other weapons of mass destruction. This does not include other military systems. Many countries feel the prohibition should be extended in the Treaty. Other military systems may involve anti-satellite weapons, (ASATS), emitting or simply placing technologies in space using laser and /or particle beams from space to intercept presently specific military targets such as ballistic missiles and hostile satellites, but in the future this may extend to destroying a target on earth. Military presence in space however, is not founded on weapons alone, but also through military surveillance systems and seen by some countries as an effective measure in verification on arms control. It is also seen as intensifying an arms race. At the forefront of the debate for space weapons is the possibility of countries deploying a National Missile Defence system. How does one reconcile such a system with present treaties? There has always been a direct relationship between weapons and space exploration, particularly if traced through the history of the late nineteenth century to the era of the space race. Konstantin Tsiolkovsky, (1857 - 1935), was one of the founders to astronautics. Robert Goddard, (1882-1945) an Englishman, developed Tsiolkovskys' work further. He built the first liquid-fuelled rocket. Goddard's work coincided with the work of a German scientist Werner Von Braun, (1912-77) who designed the V1 and V2 rocket. The V2 was the first intercontinental ballistic missile. Compared to the V1, the V2 could carry a heavier payload and the range was much longer. Von Braun had originally sketched his ideas to the Germans, that the V2 was an effective design for space travel and it was rejected. After the war the V2 became the foundation to many new technologies and these modifications marked the beginning of the space race. This competition led to space travel, taking men to the moon using the Saturn V rocket, robotic missions to the planets, and into tactical nuclear missiles (Redstone). This also marked the future for such dual-purpose technologies (i.e. military and/or civilian use) and more interestingly it took the design of weapons for space travel to be taken seriously. Arthur C Clarke commented on the possibilities of placing weapons in outer space, `the only defence against the weapons of the future is to prevent them ever being used. The problem is political and not military at all.' Ambassador Peter Jankowitsch, quoting Stockholm International Peace Research Institute in his opening address to COPUOS in Austria 1978, `we must make sure that outer space can be spared the fate of so many human discoveries of previous ages, namely becoming a mere battlefield.' These statements may be analysed by applying the United Nations Charter alongside other international treaties, such as the Outer Space Treaty 1967, the Test Ban Treaty 1963 and the Anti-Ballistic Missile Treaty in conjunction with the new Agreement signed by Russian and the USA. This may assist to highlight and conclude where problems reside whether political, legal, military, or a combination; and the impact for international peace and security.

Twelve Scientific Specialists of the Peenemuende Team

NASA Technical Reports Server (NTRS)

2004-01-01

Twelve scientific specialists of the Peenemuende team at the front of Building 4488, Redstone Arsenal, Huntsville, Alabama. They led the Army's space efforts at ABMA before transfer of the team to National Aeronautic and Space Administration (NASA), George C. Marshall Space Flight Center (MSFC). (Left to right) Dr. Ernst Stuhlinger, Director, Research Projects Office; Dr. Helmut Hoelzer, Director, Computation Laboratory: Karl L. Heimburg, Director, Test Laboratory; Dr. Ernst Geissler, Director, Aeroballistics Laboratory; Erich W. Neubert, Director, Systems Analysis Reliability Laboratory; Dr. Walter Haeussermarn, Director, Guidance and Control Laboratory; Dr. Wernher von Braun, Director Development Operations Division; William A. Mrazek, Director, Structures and Mechanics Laboratory; Hans Hueter, Director, System Support Equipment Laboratory;Eberhard Rees, Deputy Director, Development Operations Division; Dr. Kurt Debus, Director Missile Firing Laboratory; Hans H. Maus, Director, Fabrication and Assembly Engineering Laboratory

Phylogenetic lineages in Pseudocercospora

PubMed Central

Crous, P.W.; Braun, U.; Hunter, G.C.; Wingfield, M.J.; Verkley, G.J.M.; Shin, H.-D.; Nakashima, C.; Groenewald, J.Z.

2013-01-01

Pseudocercospora is a large cosmopolitan genus of plant pathogenic fungi that are commonly associated with leaf and fruit spots as well as blights on a wide range of plant hosts. They occur in arid as well as wet environments and in a wide range of climates including cool temperate, sub-tropical and tropical regions. Pseudocercospora is now treated as a genus in its own right, although formerly recognised as either an anamorphic state of Mycosphaerella or having mycosphaerella-like teleomorphs. The aim of this study was to sequence the partial 28S nuclear ribosomal RNA gene of a selected set of isolates to resolve phylogenetic generic limits within the Pseudocercospora complex. From these data, 14 clades are recognised, six of which cluster in Mycosphaerellaceae. Pseudocercospora s. str. represents a distinct clade, sister to Passalora eucalypti, and a clade representing the genera Scolecostigmina, Trochophora and Pallidocercospora gen. nov., taxa formerly accommodated in the Mycosphaerella heimii complex and characterised by smooth, pale brown conidia, as well as the formation of red crystals in agar media. Other clades in Mycosphaerellaceae include Sonderhenia, Microcyclosporella, and Paracercospora. Pseudocercosporella resides in a large clade along with Phloeospora, Miuraea, Cercospora and Septoria. Additional clades represent Dissoconiaceae, Teratosphaeriaceae, Cladosporiaceae, and the genera Xenostigmina, Strelitziana, Cyphellophora and Thedgonia. The genus Phaeomycocentrospora is introduced to accommodate Mycocentrospora cantuariensis, primarily distinguished from Pseudocercospora based on its hyaline hyphae, broad conidiogenous loci and hila. Host specificity was considered for 146 species of Pseudocercospora occurring on 115 host genera from 33 countries. Partial nucleotide sequence data for three gene loci, ITS, EF-1α, and ACT suggest that the majority of these species are host specific. Species identified on the basis of host, symptomatology and general morphology, within the same geographic region, frequently differed phylogenetically, indicating that the application of European and American names to Asian taxa, and vice versa, was often not warranted. Taxonomic novelties: New genera - Pallidocercospora Crous, Phaeomycocentrospora Crous, H.D. Shin & U. Braun; New species - Cercospora eucommiae Crous, U. Braun & H.D. Shin, Microcyclospora quercina Crous & Verkley, Pseudocercospora ampelopsis Crous, U. Braun & H.D. Shin, Pseudocercospora cercidicola Crous, U. Braun & C. Nakash., Pseudocercospora crispans G.C. Hunter & Crous, Pseudocercospora crocea Crous, U. Braun, G.C. Hunter & H.D. Shin, Pseudocercospora haiweiensis Crous & X. Zhou, Pseudocercospora humulicola Crous, U. Braun & H.D. Shin, Pseudocercospora marginalis G.C. Hunter, Crous, U. Braun & H.D. Shin, Pseudocercospora ocimi-basilici Crous, M.E. Palm & U. Braun, Pseudocercospora plectranthi G.C. Hunter, Crous, U. Braun & H.D. Shin, Pseudocercospora proteae Crous, Pseudocercospora pseudostigmina-platani Crous, U. Braun & H.D. Shin, Pseudocercospora pyracanthigena Crous, U. Braun & H.D. Shin, Pseudocercospora ravenalicola G.C. Hunter & Crous, Pseudocercospora rhamnellae G.C. Hunter, H.D. Shin, U. Braun & Crous, Pseudocercospora rhododendri-indici Crous, U. Braun & H.D. Shin, Pseudocercospora tibouchinigena Crous & U. Braun, Pseudocercospora xanthocercidis Crous, U. Braun & A. Wood, Pseudocercosporella koreana Crous, U. Braun & H.D. Shin; New combinations - Pallidocercospora acaciigena (Crous & M.J. Wingf.) Crous & M.J. Wingf., Pallidocercospora crystallina (Crous & M.J. Wingf.) Crous & M.J. Wingf., Pallidocercospora heimii (Crous) Crous, Pallidocercospora heimioides (Crous & M.J. Wingf.) Crous & M.J. Wingf., Pallidocercospora holualoana (Crous, Joanne E. Taylor & M.E. Palm) Crous, Pallidocercospora konae (Crous, Joanne E. Taylor & M.E. Palm) Crous, Pallidoocercospora irregulariramosa (Crous & M.J. Wingf.) Crous & M.J. Wingf., Phaeomycocentrospora cantuariensis (E.S. Salmon & Wormald) Crous, H.D. Shin & U. Braun, Pseudocercospora hakeae (U. Braun & Crous) U. Braun & Crous, Pseudocercospora leucadendri (Cooke) U. Braun & Crous, Pseudocercospora snelliana (Reichert) U. Braun, H.D. Shin, C. Nakash. & Crous, Pseudocercosporella chaenomelis (Y. Suto) C. Nakash., Crous, U. Braun & H.D. Shin; Typifications: Epitypifications - Pseudocercospora angolensis (T. Carvalho & O. Mendes) Crous & U. Braun, Pseudocercospora araliae (Henn.) Deighton, Pseudocercospora cercidis-chinensis H.D. Shin & U. Braun, Pseudocercospora corylopsidis (Togashi & Katsuki) C. Nakash. & Tak. Kobay., Pseudocercospora dovyalidis (Chupp & Doidge) Deighton, Pseudocercospora fukuokaensis (Chupp) X.J. Liu & Y.L. Guo, Pseudocercospora humuli (Hori) Y.L. Guo & X.J. Liu, Pseudocercospora kiggelariae (Syd.) Crous & U. Braun, Pseudocercospora lyoniae (Katsuki & Tak. Kobay.) Deighton, Pseudocercospora lythri H.D. Shin & U. Braun, Pseudocercospora sambucigena U. Braun, Crous & K. Schub., Pseudocercospora stephanandrae (Tak. Kobay. & H. Horie) C. Nakash. & Tak. Kobay., Pseudocercospora viburnigena U. Braun & Crous, Pseudocercosporella chaenomelis (Y. Suto) C. Nakash., Crous, U. Braun & H.D. Shin, Xenostigmina zilleri (A. Funk) Crous; Lectotypification - Pseudocercospora ocimicola (Petr. & Cif.) Deighton; Neotypifications - Pseudocercospora kiggelariae (Syd.) Crous & U. Braun, Pseudocercospora lonicericola (W. Yamam.) Deighton, Pseudocercospora zelkovae (Hori) X.J. Liu & Y.L. Guo. PMID:24014898

Origin of Marshall Space Flight Center (MSFC)

NASA Image and Video Library

2004-04-15

Twelve scientific specialists of the Peenemuende team at the front of Building 4488, Redstone Arsenal, Huntsville, Alabama. They led the Army's space efforts at ABMA before transfer of the team to National Aeronautic and Space Administration (NASA), George C. Marshall Space Flight Center (MSFC). (Left to right) Dr. Ernst Stuhlinger, Director, Research Projects Office; Dr. Helmut Hoelzer, Director, Computation Laboratory: Karl L. Heimburg, Director, Test Laboratory; Dr. Ernst Geissler, Director, Aeroballistics Laboratory; Erich W. Neubert, Director, Systems Analysis Reliability Laboratory; Dr. Walter Haeussermarn, Director, Guidance and Control Laboratory; Dr. Wernher von Braun, Director Development Operations Division; William A. Mrazek, Director, Structures and Mechanics Laboratory; Hans Hueter, Director, System Support Equipment Laboratory;Eberhard Rees, Deputy Director, Development Operations Division; Dr. Kurt Debus, Director Missile Firing Laboratory; Hans H. Maus, Director, Fabrication and Assembly Engineering Laboratory

The humanation of Mars

NASA Astrophysics Data System (ADS)

David, L. W.

Early developments related to human excursions to Mars are examined, taking into account plans considered by von Braun, and the 'ambitious goal of a manned flight to Mars by the end of the century', proposed at the launch of Apollo 11. In response to public reaction, plans for manned flights to Mars in the immediate future were given up, and unmanned reconnaissance of Mars was continued. An investigation is conducted concerning the advantages of manned exploration of Mars in comparison to a study by unmanned space probes, and arguments regarding a justification for interplanetary flight to Mars are discussed. Attention is given to the possibility to consider Mars as a 'back-up' planet for preserving earth life, an international Mars expedition as a world peace project, the role of Mars in connection with resource utilization considerations, and questions of exploration ethics.

Early Rockets

NASA Image and Video Library

2004-04-15

This photograph is of the engine for the Redstone rocket. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by the Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and the production was begun in 1952. Redstone rockets became the "reliable workhorse" for America's early space program. As an example of its versatility, the Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile.

Redstone Missile

NASA Technical Reports Server (NTRS)

2004-01-01

The image depicts Redstone missile being erected. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and the production was begun in 1952. Redstone rockets became the 'reliable workhorse' for America's early space program. As an example of the versatility, Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile

Werner Forssmann, Eberswalde, the 1956 Nobel Prize for medicine.

PubMed

Hollmann, Wildor

2006-10-27

Since October 1949 Werner Forssmann was a regular guest of Prof. Dr. Hugo Wilhelm Knipping in the Medical University Clinic of Cologne. Established himself as urologist in Bad Kreuznach, Werner Forssmann had read about the American further development of heart catherization, which was invented by himself. Prof. Wilhelm Bolt, who was one of the medical station doctors of the Cologne Clinic, had already learned the technique of heart catherization in 1947. Thus, it was routinely performed in patients at the Cologne University Hospital. A close collaboration between Werner Forssmann and our research group (Hugo Wilhelm Knipping, Wilhelm Bolt, Helmut Valentin, Helmut Venrath, Hans Rink, Wildor Hollmann) was established. After the notification that Werner Forssmann had been awarded the Nobel Prize for Medicine in 1956, Hugo Wilhelm Knipping instructed me to help Werner Forssmann with the preparation of his lecture. Details of events in the year 1956 are illustrated. One of the important developments in which Werner Forssmann participated with the Medical University Clinic of Cologne was the selective pulmonary angiography.

Early Rockets

NASA Image and Video Library

2004-04-15

The image depicts Redstone missile being erected. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and the production was begun in 1952. Redstone rockets became the "reliable workhorse" for America's early space program. As an example of the versatility, Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile

U.S. satellite proposals, 1945-49

NASA Technical Reports Server (NTRS)

Saegesser, L. D.

1977-01-01

Views concerning the possibility of the development of multistage rockets capable of orbiting the earth had been expressed by von Braun during an interview with members of a U.S. technical intelligence team in 1945. Recommendations to adopt a program with the ultimate objective of launching an earth satellite were submitted in October 1945 by a committee established within the Navy Bureau of Aeronautics. In 1946 it was recommended by the Aeronautical Board that the services proceed independently with their satellite studies. A report concerning the 'preliminary design of an experimental world-circling spaceship' was published by RAND on May 2, 1946. RAND in early 1949 was again asked to study for the Air Force the possible uses of earth satellites. The reasons which prevented at that time a further development and implementation of initial concepts and study results are examined

Around Marshall

NASA Image and Video Library

1962-03-08

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation’s space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. Standing at the Apollo Applications Program Cluster Model in building 4745 are (left-to-right): Dr. Wernher von Braun, MSFC; Congressman Joe D. Waggoner, Democratic representative of Louisiana; Congressman Earle Cabell, Democratic representative of Texas; Subcommittee Chairman Olin E. Teague, Democratic representative of Texas; Congressman James G. Fulton, Republican representative of Pennsylvania; and Dr. Ernst Stuhlinger, associate MSFC director for science. The subcommittee was briefed on MSFC’s manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program.

Comparison Between Billroth-II with Braun and Roux-en-Y Reconstruction After Laparoscopic Distal Gastrectomy.

PubMed

In Choi, Chang; Baek, Dong Hoon; Lee, Si Hak; Hwang, Sun Hwi; Kim, Dae Hwan; Kim, Kwang Ha; Jeon, Tae Yong; Kim, Dong Heon

2016-06-01

This study aims to compare the effectiveness of Billroth-II with Braun and Roux-en-Y reconstruction after laparoscopic distal gastrectomy. From April 2010 to August 2012, 66 patients underwent laparoscopic distal gastrectomy (Billroth-II with Braun reconstruction, 26; Roux-en-Y, 40). The patients' data were collected prospectively and reviewed retrospectively. The mean operation and reconstruction times were statistically shorter for Billroth-II with Braun reconstruction than Roux-en-Y (198.1 ± 33.0 vs. 242.3 ± 58.1 min, p = 0.001). One case of postoperative stricture was observed in each group. One case each of intra-abdominal abscess and delayed gastric emptying occurred in the Billroth-II with Braun group. At 1 year postoperatively, gastric residue and reflux esophagitis were not significantly different between the groups. Gastritis and bile reflux were more frequently observed in the Billroth-II with Braun group (p = 0.004 and p < 0.001, respectively). At 2 years postoperatively, gastric residue was not significantly different, but gastritis, bile reflux, and esophagitis were more frequent in the Billroth-II with Braun group (p = 0.029, p < 0.001, and p = 0.036, respectively). The postoperative effectiveness of Roux-en-Y reconstruction may be superior to Billroth-II with Braun reconstruction after laparoscopic distal gastrectomy.

Members of House Committee on Science and Astronautics Visited MSFC

NASA Technical Reports Server (NTRS)

1962-01-01

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. Standing at the Apollo Applications Program Cluster Model in building 4745 are (left-to-right): Dr. Wernher von Braun, MSFC; Congressman Joe D. Waggoner, Democratic representative of Louisiana; Congressman Earle Cabell, Democratic representative of Texas; Subcommittee Chairman Olin E. Teague, Democratic representative of Texas; Congressman James G. Fulton, Republican representative of Pennsylvania; and Dr. Ernst Stuhlinger, associate MSFC director for science. The subcommittee was briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program.

Saturn Apollo Program

NASA Image and Video Library

1969-07-16

At the press site, thousands of news reporters from the world over watched, taking many pictures, as the Saturn V launch vehicle (AS-506) lifted off to start Apollo 11 on its historic mission to land on the Moon. The total number of news people officially registered to cover the launch was 3,497. The craft lifted off from launch pad 39 at Kennedy Space Flight Center (KSC) on July 16, 1969. A three man crew included astronauts Neil A. Armstrong, commander; Michael Collins, Command Module(CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The mission finalized with splashdown into the Pacific Ocean on July 24, 1969. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished. The Saturn V was developed by the Marshall Space Flight Center (MSFC) under the direction of Werher von Braun.

Comparing Future Options for Human Space Flight

NASA Technical Reports Server (NTRS)

Sherwood, Brent

2010-01-01

The paper analyzes the "value proposition" for government-funded human space flight, a vexing question that persistently dogs efforts to justify its $10(exp 10)/year expense in the U.S. The original Mercury/Gemini/Apollo value proposition is not valid today. Neither was it the value proposition actually promoted by von Braun, which the post-Apollo 80% of human space flight history has persistently attempted to fulfill. Divergent potential objectives for human space flight are captured in four strategic options - Explore Mars; accelerate Space Passenger Travel; enable Space Power for Earth; and Settle the Moon - which are then analyzed for their Purpose, societal Myth, Legacy benefits, core Needs, and result as measured by the number and type of humans they would fly in space. This simple framework is proposed as a way to support productive dialogue with public and other stakeholders, to determine a sustainable value proposition for human space flight.

Early Rockets

NASA Image and Video Library

1958-05-15

Redstone missile No. 1002 on the launch pad at Cape Canaveral, Florida, on May 16, 1958. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by the Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and production was begun in 1952. Redstone rockets became the "reliable workhorse" for America's early space program. As an example of the versatility, Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile

Saturn Apollo Program

NASA Image and Video Library

1969-07-16

Aboard a Saturn V launch vehicle, the Apollo 11 mission launched from The Kennedy Space Center, Florida on July 16, 1969 and safely returned to Earth on July 24, 1969. The space vehicle is shown here during the rollout for launch preparation. The 3-man crew aboard the flight consisted of Neil A. Armstrong, commander; Michael Collins, Command Module pilot; and Edwin E. Aldrin Jr., Lunar Module pilot. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. The crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. The surface exploration was concluded in 2½ hours. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished. The Saturn V launch vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun.

Another convex combination of product states for the separable Werner state

DOE Office of Scientific and Technical Information (OSTI.GOV)

Azuma, Hiroo; Ban, Masashi; CREST, Japan Science and Technology Agency, 1-1-9 Yaesu, Chuo-ku, Tokyo 103-0028

2006-03-15

In this paper, we write down the separable Werner state in a two-qubit system explicitly as a convex combination of product states, which is different from the convex combination obtained by Wootters' method. The Werner state in a two-qubit system has a single real parameter and varies from inseparable to separable according to the value of its parameter. We derive a hidden variable model that is induced by our decomposed form for the separable Werner state. From our explicit form of the convex combination of product states, we understand the following: The critical point of the parameter for separability ofmore » the Werner state comes from positivity of local density operators of the qubits.« less

Redstone Missile on Launch Pad

NASA Technical Reports Server (NTRS)

1958-01-01

Redstone missile No. 1002 on the launch pad at Cape Canaveral, Florida, on May 16, 1958. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by the Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and production was begun in 1952. Redstone rockets became the 'reliable workhorse' for America's early space program. As an example of the versatility, Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile

Rocket Propulsion Research at Lewis Research Center

NASA Technical Reports Server (NTRS)

Dawson, Virginia P.

1992-01-01

A small contingent of engineers at NASA Lewis Research Center pioneered in basic research on liquid propellants for rockets shortly after World War II. Carried on through the 1950s, this work influenced the important early decisions made by Abe Silverstein when he took charge of the Office of Space Flight Programs for NASA. He strongly supported the development of liquid hydrogen as a propulsion fuel in the face of resistance from Wernher von Braun. Members of the Lewis staff played an important role in bringing liquid hydrogen technology to the point of reliability through their management of the Centaur Program. This paper demonstrates how the personality and engineering intuition of Abe Silverstein shaped the Centaur program and left a lasting imprint on the laboratory research tradition. Many of the current leaders of Lewis Research Center received their first hands-on engineering experience when they worked on the Centaur program in the 1960s.

2002 Microgravity Materials Science Conference

NASA Technical Reports Server (NTRS)

Gillies, Donald (Editor); Ramachandran, Narayanan (Editor); Murphy, Karen (Editor); McCauley, Dannah (Editor); Bennett, Nancy (Editor)

2003-01-01

The 2002 Microgravity Materials Science Conference was held June 25-26, 2002, at the Von Braun Center, Huntsville, Alabama. Organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Physical Sciences Research Division, NASA Headquarters, and hosted by NASA Marshall Space Flight Center and member institutions under the Cooperative Research in Biology and Materials Science (CORBAMS) agreement, the conference provided a forum to review the current research and activities in materials science, discuss the envisioned long-term goals, highlight new crosscutting research areas of particular interest to the Physical Sciences Research Division, and inform the materials science community of research opportunities in reduced gravity. An abstracts book was published and distributed at the conference to the approximately 240 people attending, who represented industry, academia, and other NASA Centers. This CD-ROM proceedings is comprised of the research reports submitted by the Principal Investigators in the Microgravity Materials Science program.

Around Marshall

NASA Image and Video Library

1968-04-24

Pictured from the left, in the Saturn I mockup, are: William Brooksbank, Marshall Space Flight Center (MSFC) Propulsion and Vehicle Engineering Laboratory; Dr. Thomas O. Paine, Deputy Administrator of the National Aeronautics and Space Administration (NASA); Dr. Wernher von Braun, MSFC director; Colonel Clare F. Farley, executive officer of the Office of the Administrator; and Charles J. Donlan, newly appointed deputy associate administrator for Manned Space Flight, technical. The party examined an ordinary man’s shoe (held by Paine) outfitted for use in the Saturn I Workshop. The shoe had a unique fastener built into the sole to allow an astronaut to move about the workshop floor and to remain in one position if he desired. Dr. Paine and his party indulged in a two-day tour at the Marshall Space Flight Center getting acquainted with Marshall personnel and programs. It was Paine’s first visit to the center since assuming the NASA post on February 1, 1968.

Apollo 11 Launched Via Saturn V Rocket

NASA Technical Reports Server (NTRS)

1969-01-01

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle produced a holocaust of flames as it rose from its pad at Launch complex 39. The 363 foot tall, 6,400,000 pound rocket hurled the spacecraft into Earth parking orbit and then placed it on the trajectory to the moon for man's first lunar landing. The Saturn V was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard the spacecraft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module pilot; and Edwin E. Aldrin Jr., Lunar Module pilot. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Comparing future options for human space flight

NASA Astrophysics Data System (ADS)

Sherwood, Brent

2011-09-01

The paper analyzes the "value proposition" for government-funded human space flight, a vexing question that persistently dogs efforts to justify its $10 10/year expense in the US. The original Mercury/Gemini/Apollo value proposition is not valid today. Neither was it the value proposition actually promoted by von Braun, which the post-Apollo 80% of human space flight history has persistently attempted to fulfill. Divergent potential objectives for human space flight are captured in four strategic options— Explore Mars; accelerate Space Passenger Travel; enable Space Power for Earth; and Settle the Moon—which are then analyzed for their purpose, societal myth, legacy benefits, core needs, and result as measured by the number and type of humans they would fly in space. This simple framework is proposed as a way to support productive dialog with public and other stakeholders, to determine a sustainable value proposition for human space flight.

Flying on Sun Shine: Sailing in Space

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alhorn, Dean

2012-03-28

On January 20th, 2011, NanoSail-D successfully deployed its sail in space. It was the first solar sail vehicle to orbit the earth and the second sail ever unfurled in space. The 10m2 sail, deployment mechanism and electronics were packed into a 3U CubeSat with a volume of about 3500cc. The NanoSail-D mission had two objectives: eject a nanosatellite from a minisatellite; deploy its sail from a highly compacted volume to validate large structure deployment and potential de-orbit technologies. NanoSail-D was jointly developed by NASA's Marshall Space Flight Center and Ames Research Center. The ManTech/NeXolve Corporation provided key sail design support.more » NanoSail-D is managed by Marshall and jointly sponsored by the Army Space and Missile Defense Command, the Space Test Program, the Von Braun Center for Science and Innovation and Dynetics Inc. The presentation will provide insights into sailcraft advances and potential missions enabled by this emerging in-space propulsion technology.« less

Effects of adding Braun jejunojejunostomy to standard Whipple procedure on reduction of afferent loop syndrome - a randomized clinical trial.

PubMed

Kakaei, Farzad; Beheshtirouy, Samad; Nejatollahi, Seyed Moahammad Reza; Rashidi, Iqbal; Asvadi, Touraj; Habibzadeh, Afshin; Oliaei-Motlagh, Mohammad

2015-12-01

Whipple surgery (pancreaticodeudenectomy) has a high complication rate. We aimed to evaluate whether adding Braun jejunojejunostomy (side-to-side anastomosis of afferent and efferent loops distal to the gastrojejunostomy site) to a standard Whipple procedure would reduce postoperative complications. We conducted a randomized clinical trial comparing patients who underwent standard Whipple surgery (standard group) and patients who underwent standard Whipple surgery with Braun jejunojejunostomy (Braun group). Patients were followed for 1 month after the procedure and postoperative complications were recorded. Our study included 30 patients: 15 in the Braun and 15 in the standard group. In the Braun group, 4 (26.7%) patients experienced 6 complications, whereas in the standard group, 7 (46.7%) patients experienced 11 complications (p = 0.14). Complications in the Braun group were gastrointestinal bleeding and wound infection (n = 1 each) and delayed gastric emptying and pulmonary infection (n = 2 each). Complications in the standard group were death, pancreatic anastomosis leak and biliary anastomosis leak (n = 1 each); gastrointestinal bleeding (n = 2); and afferent loop syndrome and delayed gastric emptying (n = 3 each). There was no significant difference between groups in the subtypes of complications. Our results showed that adding Braun jejunojejunostomy to standard Whipple procedure was associated with lower rates of afferent loop syndrome and delayed gastric emptying. However, more studies are needed to define the role of Braun jejunojejunostomy in this regard. IRCT2014020316473N1 (www.irct.ir).

Generation of Werner states via collective decay of coherently driven atoms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agarwal, Girish S.; Kapale, Kishore T.

2006-02-15

We show deterministic generation of Werner states as a steady state of the collective decay dynamics of a pair of neutral atoms coupled to a leaky cavity and strong coherent drive. We also show how the scheme can be extended to generate a 2N-particle analogue of the bipartite Werner states.

Rocket propulsion research at Lewis Research Center

NASA Technical Reports Server (NTRS)

Dawson, Virginia P.

1992-01-01

A small contingent of engineers at NASA LeRC pioneered the basic research on liquid propellants for rockets shortly after World War 2. Carried on through the 1950s, this work influenced the important early decisions made by Abe Silverstein when he took charge of the Office of Space Flight Programs for NASA. He strongly supported the development of liquid hydrogen as a propulsion fuel in the face of resistance from Wernher von Braun. Members of the LeRC staff played an important role in bringing liquid hydrogen technology to the point of reliability through their management of the Centaur Program. This paper demonstrates how the personality and engineering intuition of Abe Silverstein shaped the Centaur program and left a lasting imprint on the laboratory research tradition. Many of the current leaders of LeRC received their first hands-on engineering experience when they worked on the Centaur program in the 1960s.

The Space Station - Past, present and future with some thoughts on some legal questions that need to be addressed

NASA Technical Reports Server (NTRS)

Hosenball, S. N.

1985-01-01

The history of the concept of a space station is briefly considered, taking into account a story written by Hale (1869), quantitative work provided by Oberth and Tsiolkovsky, von Braun, and the U.S. decision regarding the establishment of a space station. Arguments in favor of constructing a space station are related to the utility of a laboratory in earth orbit, the importance of a repair and maintenance base for satellites, the provision of capabilities for the commercial utilization of space, and the employment of a space station as a staging base for missions to the moon, Mars, and, possibly, the asteroids. Plans for the implementation of the Space Station concept are discussed, taking into account also legal issues involved in such an implementation. Attention is given to questions regarding the applicability of the Liability convention, U.S. domestic law, the domestic law of other countries, and four treaties.

Explorer 1 60th Anniversary

NASA Image and Video Library

2018-01-31

Michael Watkins, Director of NASA's Jet Propulsion Laboratory, left, Susan Finley, who began working at NASA's Jet Propulsion Laboratory in January 1958 as a "human computer", center, and Thomas Zurbuchen, Associate Administrator for NASA's Science Mission Directorate, right, reenact the famous picture of Dr. William H. Pickering, Dr. James A. van Allen, and Dr. Wernher von Braun, hoisting a model of Explorer 1 above their heads at a press conference announcing the satellite's success with a replica of the Explorer 1 satellite during an event celebrating the 60th Anniversary of the Explorer 1 mission and the discovery of Earth's radiation belts, Wednesday, Jan. 31, 2018, at the National Academy of Sciences in Washington. The first U.S. satellite, Explorer 1, was launched from Cape Canaveral on January 31, 1958. The 30-pound satellite would yield a major scientific discovery, the Van Allen radiation belts circling our planet, and begin six decades of groundbreaking space science and human exploration. (NASA/Joel Kowsky)

The First Robotics Rocket City Regional Competition

NASA Image and Video Library

2018-03-16

Johnny Stephenson, director of NASA Marshall Space Flight Center's Office of Strategic Analysis & Communications, addresses the crowd during the March 16 award ceremony following the first day of competition at the FIRST Robotics Rocket City Regional at the Von Braun Center in Huntsville. Ed Sparks, of the Morgan County Mech Tech team, received the award for Volunteer of the Year at the March 16 award ceremony. Mech Tech, comprised of students from five high schools in Morgan County, Alabama, also won the Industrial Design Award. The team was one of three regional finalists that will advance to the FIRST national championships April 18-21 in Houston. The other two regional finalists were Burning Magnetos of Fort Dorchester High School in North Charleston, South Carolina, and OGRE of Opelika High School in Opelika, Alabama. Mech Tech and Golden Hurricane from Columbia High School in Huntsville, were "house" teams sponsored by Marshall.

NASA Deputy Administrator Tours Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

1968-01-01

Pictured from the left, in the Saturn I mockup, are: William Brooksbank, Marshall Space Flight Center (MSFC) Propulsion and Vehicle Engineering Laboratory; Dr. Thomas O. Paine, Deputy Administrator of the National Aeronautics and Space Administration (NASA); Dr. Wernher von Braun, MSFC director; Colonel Clare F. Farley, executive officer of the Office of the Administrator; and Charles J. Donlan, newly appointed deputy associate administrator for Manned Space Flight, technical. The party examined an ordinary man's shoe (held by Paine) outfitted for use in the Saturn I Workshop. The shoe had a unique fastener built into the sole to allow an astronaut to move about the workshop floor and to remain in one position if he desired. Dr. Paine and his party indulged in a two-day tour at the Marshall Space Flight Center getting acquainted with Marshall personnel and programs. It was Paine's first visit to the center since assuming the NASA post on February 1, 1968.

Replicas of the Santa Maria, Nina, Pinta sail by OV-105 on KSC LC Pad 39B

NASA Image and Video Library

1992-05-06

S92-39074 (6 May 1992) --- The centuries-old technology that built Christopher Columbus' three sailing ships passes within a half mile of the 20th-Century Space Shuttle Endeavour, in background, awaiting liftoff on Launch Pad 39B. The replicas of the Santa Maria, Nina, and Pinta wind-powered ships, managed by the Spain '92 Foundation, are on a tour to ports around the Gulf of Mexico and up the Atlantic Coast of the United States. Endeavour is set to lift off on its maiden voyage, STS-49, on May 7, 1992. Video footage of the two types of exploration vessels will be used by NASA for a variety of productions, including the annual Von Braun Exploration forum sponsored by NASA's Marshall Space Flight Center (MSFC), Huntsville, Alabama, in October, 1992. This year's theme is Exploration and the Evolution of Nations. 1992 is the 500th anniversary of Columbus' voyage to the New World.

History of Artificial Gravity. Chapter 3

NASA Technical Reports Server (NTRS)

Clement, Gilles; Bukley, Angie; Paloski, William

2006-01-01

This chapter reviews the past and current projects on artificial gravity during space missions. The idea of a rotating wheel-like space station providing artificial gravity goes back in the writings of Tsiolkovsky, Noordung, and Wernher von Braun. Its most famous fictional representation is in the film 2001: A Space Odyssey, which also depicts spin-generated artificial gravity aboard a space station and a spaceship bound for Jupiter. The O Neill-type space colony provides another classic illustration of this technique. A more realistic approach to rotating the space station is to provide astronauts with a smaller centrifuge contained within a spacecraft. The astronauts would go into it for a workout, and get their gravity therapeutic dose for a certain period of time, daily or a few times a week. This simpler concept is current being tested during ground-based studies in several laboratories around the world.

The American species of the genus Glaucolepis Braun, 1917 (Neotrifurcula van Nieukerken, syn. nov.) (Lepidoptera: Nepticulidae)

USDA-ARS?s Scientific Manuscript database

We provide diagnostic characters for the genus Glaucolepis Braun, re-examine the type series of the type species of the North American G. saccharella Braun, describe two new species from Chile and Argentina (G. flagellata Remeikis & Stonis, sp. nov. and G. pseudoflagellata Remeikis & Stonis, sp. nov...

Experimental preparation of the Werner state via spontaneous parametric down-conversion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang Yongsheng; Huang Yunfeng; Li Chuanfeng

2002-12-01

We present an experiment for preparing a Werner state via spontaneous parametric down-conversion and controlled decoherence of photons in this paper. In this experiment two independent {beta}-barium borate crystals are used to produce down-conversion light beams, which are mixed to prepare the Werner state.

Identifying Sociological Factors for the Success of Space Exploration

NASA Astrophysics Data System (ADS)

Lundquist, C. A.; Tarter, D.; Coleman, A.

Astrosociology factors relevant to success of future space exploration may best be identified through studies of sociological circumstances of past successful explorations, such as the Apollo-Lunar Missions. These studies benefit from access to primary records of the past programs. The Archives and Special Collections Division of the Salmon Library at the University of Alabama Huntsville (UAH) houses large collections of material from the early periods of the space age. The Huntsville campus of the University of Alabama System had its birth in the mid-1950s at the time when the von Braun rocket team was relocated from Texas to Huntsville. The University, the City of Huntsville and the US Government rocket organizations developed in parallel over subsequent years. As a result, the University has a significant space heritage and focus. This is true not only for the engineering and science disciplines, but also for the social sciences. The life of the University spans the period when Huntsville government and industrial organizations were responsible for producing the rocket vehicles to first take mankind to the Moon. That endeavor was surely as significant sociologically as technologically. In the 1980s, Donald E. Tarter, conducted a series of video interviews with some leading members of the original von Braun team. Although the interviews ranged over many engineering subjects, they also recorded personal features of people involved in the Apollo lunar exploration program and the interactions between these people. Such knowledge was of course an objective. These interviews are now in the collections of the UAH Library Archives, along with extensive documentation from the same period. Under sponsorship of the Archives and the NASA-Marshall Retiree Association, the interview series was restarted in 2006 to obtain comparable oral-history interviews with more than fifty US born members of the rocket team from the 1960s. Again these video interviews are rich with insights into the people involved in the Apollo lunar exploration program. A common thought in the original and recent interviews is that the 1960s rocket team was a unique assembly of people with leadership and modes of operation that has not been reproduced since. If mankind is again going to the Moon, Mars, an asteroid or elsewhere in the solar system, a similar assembly of people and sociological conditions may well be required.

Distillability of Werner states using entanglement witnesses and robust semidefinite programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vianna, Reinaldo O.; Departamento de Fisica, ICEX, Universidade Federal de Minas Gerais, Av. Antonio Carlos 6627, 31270-901 Belo Horizonte, Minas Gerais; Doherty, Andrew C.

2006-11-15

We use robust semidefinite programs and entanglement witnesses to study the distillability of Werner states. We perform exact numerical calculations that show two-undistillability in a region of the state space, which was previously conjectured to be undistillable. We also introduce bases that yield interesting expressions for the distillability witnesses and for a tensor product of Werner states with an arbitrary number of copies.

In Memoriam Werner Callebaut.

PubMed

Boniolo, Giovanni

2015-12-01

The article contains some recollections on Werner Callebaut highlighting his personal character and his role in the community of historians, philosophers and sociologists of the life sciences. Werner Callebaut (1952-2014) was a real European philosopher. He was the Scientific Director of the Konrad Lorenz Institute for Evolution and Cognition Research (KLI, Klosterneuburg, Austria) and the President of the International Society for the History, Philosophy, and Social Studies of Biology.

Apollo 11 Launched Via Saturn V Rocket - High Angle View

NASA Technical Reports Server (NTRS)

1969-01-01

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle produced a holocaust of flames as it rose from its pad at Launch complex 39. The 363 foot tall, 6,400,000 pound rocket hurled the spacecraft into Earth parking orbit and then placed it on the trajectory to the moon. This high angle view of the launch was provided by a `fisheye' camera mounted on the launch tower. The Saturn V was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard the spacecraft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

The role of philosophy in the conceptual development of quantum physics

NASA Astrophysics Data System (ADS)

Diamond, Ethel

Making a distinction between the context of discovery and the context of justification, I examine the relationship between philosophy and the discovery of quantum physics. I do this by focusing on four of the most important contributors to quantum theory: Albert Einstein, Werner Heisenberg, Erwin Schrodinger and Niels Bohr. Looking to the period immediately preceding the era in which quantum physics was developed, I first explore the scientific writings of Hermann von Helmholtz, Ernst Mach, Heinrich Hertz and Ludwig Boltzmann. In doing so, I uncover the integral role classic philosophy played in the scientific investigations of nineteenth-century German and Austrian physicists. After establishing the cultural link between scientific writing and philosophic training at that time and place in history, I investigate the formative philosophic influences on Einstein, Heisenberg, Schrodinger and Bohr. By a close examination of some of their most important scientific papers, this dissertation reveals the way in which these early twentieth-century scientists continued an important nineteenth-century European tradition of integrating philosophic thought in their scientific creative thinking.

Saturn Apollo Program

NASA Image and Video Library

1969-11-24

Sitting in the life raft, during the Apollo 12 Pacific recovery, are the three mission astronauts; Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms, while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. Apollo 12 safely returned to Earth on November 24, 1969.

The Use of Radar to Improve Rainfall Estimation over the Tennessee and San Joaquin River Valleys

NASA Technical Reports Server (NTRS)

Petersen, Walter A.; Gatlin, Patrick N.; Felix, Mariana; Carey, Lawrence D.

2010-01-01

This slide presentation provides an overview of the collaborative radar rainfall project between the Tennessee Valley Authority (TVA), the Von Braun Center for Science & Innovation (VCSI), NASA MSFC and UAHuntsville. Two systems were used in this project, Advanced Radar for Meteorological & Operational Research (ARMOR) Rainfall Estimation Processing System (AREPS), a demonstration project of real-time radar rainfall using a research radar and NEXRAD Rainfall Estimation Processing System (NREPS). The objectives, methodology, some results and validation, operational experience and lessons learned are reviewed. The presentation. Another project that is using radar to improve rainfall estimations is in California, specifically the San Joaquin River Valley. This is part of a overall project to develop a integrated tool to assist water management within the San Joaquin River Valley. This involves integrating several components: (1) Radar precipitation estimates, (2) Distributed hydro model, (3) Snowfall measurements and Surface temperature / moisture measurements. NREPS was selected to provide precipitation component.

Reflections on My Werner H. Kirsten Student Internship | Poster

Cancer.gov

By Nathalie Walker, Guest Writer Editor’s note: This article represents one student’s perspective on her experiences as a Werner H. Kirsten student intern. Failure isn’t just a possibility, it is a certainty; yet failure is what leads you to success. Above all else, that is what I will retain from my experience in the Werner H. Kirsten Student Intern Program (WHK SIP).

Saturn Apollo Program

NASA Image and Video Library

1969-12-14

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples, some of which can be seen in this photograph. Apollo 12 safely returned to Earth on November 24, 1969.

Technical Evaluation Report on the Flight Mechanics Panel Symposium on the Use of Computers as a Design Tool.

DTIC Science & Technology

1980-03-01

by Professor Dr- gfrie r Hochschule der Bundeswehr Minchen Werner - Heisenberg -Weg 39 8014 Neubiberg, Germany DTI Tl sJUN . This Advisory Report was...Wagner March 1980 10. Author’s/Editor’s Address II. Pages Hochschule der Bundeswehr MUnchen Werner - Heisenberg -Weg 39 21 8014 Neubiberg, Germany 12...SYMPOSIUM ON THE USE OF COMPUTERS AS A DESIGN TOOL by Professor Dr.-Ing. Siegfried N. Wagner Luftfahrttechnik Hochschule der Bundeswehr Mflnchen Werner

The genus Cladosporium

PubMed Central

Bensch, K.; Braun, U.; Groenewald, J.Z.; Crous, P.W.

2012-01-01

A monographic revision of the hyphomycete genus Cladosporium s. lat. (Cladosporiaceae, Capnodiales) is presented. It includes a detailed historic overview of Cladosporium and allied genera, with notes on their phylogeny, systematics and ecology. True species of Cladosporium s. str. (anamorphs of Davidiella), are characterised by having coronate conidiogenous loci and conidial hila, i.e., with a convex central dome surrounded by a raised periclinal rim. Recognised species are treated and illustrated with line drawings and photomicrographs (light as well as scanning electron microscopy). Species known from culture are described in vivo as well as in vitro on standardised media and under controlled conditions. Details on host range/substrates and the geographic distribution are given based on published accounts, and a re-examination of numerous herbarium specimens. Various keys are provided to support the identification of Cladosporium species in vivo and in vitro. Morphological datasets are supplemented by DNA barcodes (nuclear ribosomal RNA gene operon, including the internal transcribed spacer regions ITS1 and ITS2, the 5.8S nrDNA, as well as partial actin and translation elongation factor 1-α gene sequences) diagnostic for individual species. In total 993 names assigned to Cladosporium s. lat., including Heterosporium (854 in Cladosporium and 139 in Heterosporium), are treated, of which 169 are recognized in Cladosporium s. str. The other taxa are doubtful, insufficiently known or have been excluded from Cladosporium in its current circumscription and re-allocated to other genera by the authors of this monograph or previous authors. Taxonomic novelties: Cladosporium allicinum (Fr.: Fr.) Bensch, U. Braun & Crous, comb. nov., C. astroideum var. catalinense U. Braun, var. nov., Fusicladium tectonicola (Yong H. He & Z.Y. Zhang) U. Braun & Bensch, comb. nov., Septoidium uleanum (Henn.) U. Braun, comb. nov., Zasmidium adeniae (Hansf.) U. Braun, comb. nov., Zasmidium dianellae (Sawada & Katsuki) U. Braun, comb. nov., Zasmidium lythri (Westend.) U. Braun & H.D. Shin, comb. nov., Zasmidium wikstroemiae (Petch) U. Braun, comb. nov. PMID:22815589

Service-Oriented Architectures and Project Optimization for a Special Cost Management Problem Creating Synergies for Informed Change between Qualitative and Quantitative Strategic Management Processes

DTIC Science & Technology

2010-05-01

Science, Werner Heisenberg -Weg 39,85577 Neubiberg, Germany,CA,93943 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S...University of the Federal Armed Forces of Germany Institute for Theoretic Computer Science Mathematics and Operations Research Werner Heisenberg -Weg...Research Werner Heisenberg -Weg 39 85577 Neubiberg, Germany Phone +49 89 6004 2400 Marco Schuler—Marco Schuler is an active Officer of the Federal

About an Element of Human Greatness

NASA Astrophysics Data System (ADS)

Hickam, Homer

2002-01-01

What a grand day that was when Alan Shepard climbed into his Mercury capsule attached to a Redstone rocket-the rocket which would ultimately grow into the greatest rocket ever built, the Saturn V Moon rocket. When I was a boy in Coalwood, WV, my greatest hero, besides my father and my mother, was Huntsville's Dr. Wernher von Braun. After Sputnik was launched in October 1957, the newspapers we received in our little coal camp were filled with stories of how American scientists and engineers were desperately working to catch up in the space race. It was as if the science fiction I had read all my life was coming true. Gradually, I became fascinated by the whole thing. I read every article I could find about the men who built rockets and launched them, and kept myself pinned to the television set for the latest on what they were doing. Dr. von Braun's name was mentioned often. At night before I went to steep, I thought about what he might be doing at that very moment and imagined that he was down at Huntsville or Cape Canaveral high on a gantry, lying on his back like Michelangelo, working with a wrench on the fuel lines of one of his rockets. I started to think about what an adventure it would be to work for him, helping him to build rockets and launching them into space. For all I knew, a man with that much conviction might even form an expedition into space, like Lewis and Clark. Either way, I wanted to be part of his team.

Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome.

PubMed

Bagley, Mark C; Davis, Terence; Dix, Matthew C; Fusillo, Vincenzo; Pigeaux, Morgane; Rokicki, Michal J; Kipling, David

2010-09-01

The ATP-competitive p38α MAPK inhibitor VX-745 exhibits an exquisite kinase selectivity profile, is effective in blocking p38 stress signaling in Werner syndrome dermal fibroblasts, has efficacy in clinical trials and may have therapeutic value against Werner syndrome. Previous synthetic routes, however, have only resulted in milligram quantities suitable for cell-based studies, whereas gram quantities would be required for in vivo use. Microwave irradiation using a stop-flow monomodal microwave reactor has been found to facilitate scale-up of the synthesis of VX-745. Ullmann-type C-S bond formation using thiophenol, chloropyridazine, copper(I) catalyst and diol ligand proceeds rapidly and efficiently in this apparatus for elaboration to the pyrimido[1,6-b]pyridazinone core of VX-745 on gram scale and with good overall yield. This method delivers the p38 inhibitor VX-745 in sufficient quantities for preclinical studies to rescue the aging phenotype in Werner syndrome.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the second of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the third of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

View Seventeen of Lunar Panoramic Scene

NASA Technical Reports Server (NTRS)

1969-01-01

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what's known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the seventeenth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1968-11-04

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the fourth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the thirteenth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the fourteenth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the twenty-first of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the twenty-fifth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

NASA Microgravity Materials Science Conference

NASA Technical Reports Server (NTRS)

Gillies, D. C. (Compiler); McCauley, D. E. (Compiler)

1999-01-01

The Microgravity Materials Science Conference was held July 14-16, 1998 at the Von Braun Center in Huntsville, AL. It was organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Microgravity Research Division at NASA Headquarters, and hosted by the NASA Marshall Space Flight Center and the Alliance for Microgravity Materials Science and Applications. It was the third NASA conference of this type in the microgravity materials science discipline. The microgravity science program sponsored approximately 125 investigations and 100 principal investigators in FY98, almost all of whom made oral or poster presentations at this conference. The conference's purpose was to inform the materials science community of research opportunities in reduced gravity in preparation for a NASA Research Announcement scheduled for release in late 1998 by the Microgravity Research Division at NASA Headquarters. The conference was aimed at materials science researchers from academia, industry, and government. A tour of the Marshall Space Flight Center microgravity research facilities was held on July 16, 1998. This volume is comprised of the research reports submitted by the principal investigators after the conference.

NASA Microgravity Materials Science Conference

NASA Technical Reports Server (NTRS)

Szofran, Frank R. (Compiler); McCauley, D. (Compiler); Walker, C. (Compiler)

1996-01-01

The Microgravity Materials Science Conference was held June 10-11, 1996 at the Von Braun Civic Center in Huntsville, AL. It was organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Microgravity Science and Applications Division at NASA Headquarters, and hosted by the NASA Marshall Space Flight Center and the Alliance for Microgravity Materials Science and Applications (AMMSA). It was the second NASA conference of this type in the microgravity materials science discipline. The microgravity science program sponsored approximately 80 investigations and 69 principal investigators in FY96, all of whom made oral or poster presentations at this conference. The conference's purpose was to inform the materials science community of research opportunities in reduced gravity in preparation for a NASA Research Announcement (NRA) scheduled for release in late 1996 by the Microgravity Science and Applications Division at NASA Headquarters. The conference was aimed at materials science researchers from academia, industry, and government. A tour of the MSFC microgravity research facilities was held on June 12, 1996. This volume is comprised of the research reports submitted by the principal investigators after the conference and presentations made by various NASA microgravity science managers.

Saturn Apollo Program

NASA Image and Video Library

1969-11-23

This is a view of astronaut Richard F. Gordon attaching a high resolution telephoto lens to a camera aboard the Apollo 12 Command Module (CM) Yankee Clipper. The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms. Their lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. Astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the fifteenth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the sixteenth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the eighteenth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

But what will it Cost? The history of NASA cost estimating

NASA Technical Reports Server (NTRS)

Hamaker, Joseph W.

1994-01-01

Within two years of being chartered in 1958 as an independent agency to conduct civilian pursuits in aeronautics and space, NASA absorbed either wholly or partially the people, facilities, and equipment of several existing organizations. These included the laboratories of the National Advisory Committee of Aeronautics (NACA) at Langley Research Center in Virginia, Ames Research Center in California, and Lewis Research Center in Ohio; the Army Ballistic Missile Agency (ABMA) at Redstone Arsenal Alabama, for which the team of Wernher von Braun worked; and the Department of Defense Advanced Research Projects Agency (ARPA) and their ongoing work on big boosters. These were especially valuable resources to jump start the new agency in light of the shocking success of the Soviet space probe Sputnik in the autumn of the previous year and the corresponding pressure from an impatient American public to produce some response. Along with these inheritances, there came some existing systems engineering and management practices, including project cost estimating methodologies. This paper will briefly trace the origins of those methods and how they evolved within the agency over the past three decades.

Saturn Apollo Program

NASA Image and Video Library

1969-11-24

The smiling Apollo 12 astronauts peer out of the window of the mobile quarantine facility aboard the recovery ship, USS Hornet. Pictured (Left to right) are Spacecraft Commander, Charles Conrad; Command Module (CM) Pilot, Richard Gordon; and Lunar Module (LM) Pilot, Alan L. Bean. The crew were housed in the quarantine facility immediately after the Pacific recovery operation took place. The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. Apollo 12 returned safely to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the fifth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the sixth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the seventh of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the seventeenth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1959-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the twenty-third of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-11-14

The second manned lunar landing mission, Apollo 12, launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. This is the twenty-fourth of 25 images captured by the crew in attempt to provide a 360 degree Lunar surface scene. Apollo 12 safely returned to Earth on November 24, 1969.

Planetarium Inversum -- a space vision for Earth education.

PubMed

Lotsch, B

2003-01-01

In a planetarium, the visitor is sitting on Earth and looking into an imaginary space. The Planetarium Inversum is the opposite: visitors are sitting in a space station, looking down on Mother Earth. It is a scientifically-based information show with visitors involvement, its elements being partially virtual (Earth in space has to be projected with highest possible resolution) but also containing real structures, such as the visitors' Earth observatory with adjacent biological systems (plant cultures and other ecological life support components). Its main message concerns the limits and the vulnerability of our home planet, its uniqueness, beauty and above all, its irreplaceableness: Earth does not have an emergency exit. The Earth observatory is part of a ring shaped, rotating space station of the type designed by Wernher von Braun decades ago. Visitors are told that gravity is being substituted by centrifugal force. Both types of life support systems are being demonstrated--self regenerative life based ones and technical ones as a backup (solar electric splitting of water and chemical absorption of respiratory CO2). c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Theories of Intelligence, Learning, and Motivation as a Basis for Praxis

ERIC Educational Resources Information Center

Nderu-Boddington, Eulalee

2008-01-01

This paper examines how Piaget, Werner, and Gardner differ regarding the roles of cognition, intelligence, and learning in the developmental process. Piaget believes in the predominance of genetic factors. Werner stresses the influence of biological factors, while Gardner proposes that the environment plays a greater influence in how intelligence…

Excitation of the Werner bands of H2 by electron impact

NASA Technical Reports Server (NTRS)

Stone, E. J.; Zipf, E. C.

1972-01-01

Absolute cross sections for the excitation of the H2 Werner band system were measured from energy threshold to 300 eV for electron impact on H2. The bands were observed in emission in the wavelength region 1100A to 1250A. The measured cross sections were compared with published transition probabilities, leading to the conclusion that the Werner bands are suitable as the basis for a relative spectral response calibration only when the bands are observed under sufficiently high resolution. The effect of the perturbation between the C 1Pi u and B 1 Sigma-u states of the hydrogen molecule was clearly observed in anomalies in the rotational intensity distribution in bands of the (3 v '') progression.

Correlations and Werner states in finite spin linear arrays

NASA Astrophysics Data System (ADS)

Wells, P. R.; Chaves, C. M.; d'Albuquerque e Castro, J.; Koiller, Belita

2013-10-01

Pairwise quantum correlations in the ground state of an N-spins antiferromagnetic Heisenberg chain are investigated. By varying the exchange coupling between two neighboring sites, it is possible to reversibly drive spins from entangled to disentangled states. For even N, the two-spin density matrix is written in the form of a Werner state, allowing identification of its single parameter with the usual spin-spin correlation function. The N = 4 chain is identified as a promising system for practical demonstrations of non-classical correlations and the realization of Werner states in familiar condensed matter systems. Fabrication and measurement ingredients are within current capabilities.

Werner Jaeger's "Paideia" and His 'Third Humanism'

ERIC Educational Resources Information Center

Horn, Christoph

2018-01-01

Werner Jaeger (1888-1961) was at his time the most brilliant and the most influential German classicist. His most important project was a tripartite study that he finally published under the title of "Paideia. Die Formung des griechischen Menschen" (1933-1947). "Paideia" was much more than a detailed scholarly book on pedagogy…

Some special features of the le chatelier-braun principle

NASA Astrophysics Data System (ADS)

Nesis, E. I.; Skibin, Yu. N.

2000-07-01

The relaxation reaction of a system that follows from the Le Chatelier-Braun principle and weakens the result of an external influence turns out to be more intense under a complex action. A method for quantitative determination of the weakening effect for simple and complex actions is suggested.

Hyphenated history: the Böhler-Braun frame.

PubMed

Sop, Aaron L; Mehlman, Charles T; Meiss, Ludwig

2003-03-01

Throughout the history of medicine, many great physicians have originated or popularized ideas that have resulted in their names being attached to a device, procedure, or disease process. Hyphenated eponyms are especially interesting, for there are always underlying stories that explicate how people became associates in history. This paper will describe a bit of hyphenated history regarding orthopaedic trauma, specifically, the development of the Böhler-Braun frame. The lives of two great surgeons associated with this device, Lorenz Böhler, the "father of traumatology," and Heinrich Braun, the "father of local anesthesia," will also be reviewed.

A Choice Reaction Time Index of Callosal Anatomical Homotopy

ERIC Educational Resources Information Center

Desjardins, Sameul; Braun, Claude M. J.; Achim, Andre; Roberge, Carl

2009-01-01

Tachistoscopically presented bilateral stimulus pairs not parallel to the meridian produced significantly longer RTs on a task requiring discrimination of shapes (Go/no-Go) than pairs emplaced symmetrically on each side of the meridian in Desjardins and Braun [Desjardins, S., & Braun, C. M. J. (2006). Homotopy and heterotopy and the bilateral…

Label-Free THz-Optoelectronic Sensing of Ultra-Low Concentration of Genetic Sequences: Theoretical Treatment

DTIC Science & Technology

2009-12-15

Two Ferrocenium and Two Ferrocene Complexes; J. Am. Chem. Soc.; (Communication); 125(25); 7522-7523(2003) [19] Braun-Sand, S. B.; Wiest, O.; Biasing...of Two Ferrocenium and Two Ferrocene Complexes ; J. Am. Chem. Soc.; (Communication); 2003; 125(25); 7522- 7523 [35]. Sonja B. Braun-Sand and Olaf

Generation of Werner states and preservation of entanglement in a noisy environment [rapid communication

NASA Astrophysics Data System (ADS)

Jakóbczyk, Lech; Jamróz, Anna

2005-12-01

We study the influence of noisy environment on the evolution of two-atomic system in the presence of collective damping. Generation of Werner states as asymptotic stationary states of evolution is described. We also show that for some initial states the amount of entanglement is preserved during the evolution.

Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A(H1N1) virus infection

USDA-ARS?s Scientific Manuscript database

Previous studies indicate that Immulina, a commercial extract of Arthrospira (Spirulina) platensis, is a potent activator of innate immune cells and that Braun-type lipoproteins (a principal toll-like receptor (TLR) 2 ligand) are the main active components within this product. In the present study, ...

NASA chief technologist visits Stennis

NASA Image and Video Library

2010-08-26

NASA Chief Technologist Bobby Braun visited John C. Stennis Space Center on Aug. 26. While at Stennis, he spoke to employees and the media about innovation and technology in NASA's future and the important role Stennis will play in space exploration programs. Braun also toured facilities and received briefings on work under way at the nation's premier rocket engine test facility.

Saturn Apollo Program

NASA Image and Video Library

1969-11-20

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn Five launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Their lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. In this photograph, one of the astronauts on the Moon’s surface is holding a container of lunar soil. The other astronaut is seen reflected in his helmet. Apollo 12 safely returned to Earth on November 24, 1969.

Apollo 12 Astronauts Peer Out of the Mobile Quarantine Facility

NASA Technical Reports Server (NTRS)

1969-01-01

The smiling Apollo 12 astronauts peer out of the window of the mobile quarantine facility aboard the recovery ship, USS Hornet. Pictured (Left to right) are Spacecraft Commander, Charles Conrad; Command Module (CM) Pilot, Richard Gordon; and Lunar Module (LM) Pilot, Alan L. Bean. The crew were housed in the quarantine facility immediately after the Pacific recovery operation took place. The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what's known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. Apollo 12 returned safely to Earth on November 24, 1969.

Nanosail-D: The Small Satellite That Could!

NASA Technical Reports Server (NTRS)

Alhorn, Dean C.; Casas, Joseph P.; Agasid, Elwood F.; Adams, Charles L.; Laue, Greg; Kitts, Christopher; O'Brien, Sue

2011-01-01

Three years from its initial design review, NanoSail-D successfully deployed its sail on January 20th, 2011. It became the first solar sail vehicle to orbit the earth and the second sail ever unfurled in space. The NanoSail-D mission had two main objectives: eject a nanosatellite from a microsatellite; deploy its sail from a highly compacted volume and low mass system to validate large structure deployment and potential de-orbit technologies. These objectives were successfully achieved and the de-orbit analysis is in process. This paper presents an overview of the NanoSail-D project and insights into how potential setbacks were overcome. Many lessons have been learned during these past three years and are discussed in light of the phenomenal success and interest that this small satellite has generated. NanoSail-D was jointly designed and built by NASA's Marshall Space Flight Center and NASA's Ames Research Center. ManTech/NeXolve Corporation also provided key sail design support. The NanoSail-D experiment is managed by Marshall and jointly sponsored by the Army Space and Missile Defense Command, the Von Braun Center for Science and Innovation and Dynetics Inc. Ground operations support was provided by Santa Clara University, with radio beacon packets received from amateur operators around the world.

Saturn Apollo Program

NASA Image and Video Library

1969-11-23

Sitting on the lunar surface, this magnetometer provided new data on the Moon’s magnetic field. This was one of the instruments used during the Apollo 12 mission. The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. Apollo 12 safely returned to Earth on November 24, 1969.

[Comparison of the safety and the costs between laparoscopic assisted or totally laparoscopic uncut Roux-en-Y and BillrothII(+Braun reconstruction--a single center prospective cohort study].

PubMed

Wang, Yinkui; Li, Ziyu; Shan, Fei; Zhang, Lianhai; Li, Shuangxi; Jia, Yongning; Chen, Yufan; Xue, Kan; Miao, Rulin; Li, Zhemin; Gao, Xiangyu; Yan, Chao; Li, Shen; Wu, Zhouqiao; Ji, Jiafu

2018-03-25

To compare the short-term safety and costs between laparoscopic assisted or totally laparoscopic uncut Roux-en-Y and Billroth II((BII() + Braun reconstruction after radical gastrectomy of distal gastric cancer. Clinical data from our prospective database of radical gastrectomy were systematically analyzed. The patients who underwent laparoscopic gastrectomy with uncut Roux-en-Y or BII(+ Braun reconstruction between March 1st, 2015 and June 30th, 2017 were screened out for further analysis. Both the reconstructions were completed by linear staplers. Uncut Roux-en-Y reconstruction was performed with a 45 mm no-knife linear stapler (ATS45NK) on the afferent loop below the gastrojejunostomy. Continuous variables were compared using independent samples t test or Mann-Whitney U. The frequencies of categorical variables were compared using Chi-squared or Fisher exact test. Eighty-one patients were in uncut Roux-en-Y group and 58 patients were in BII(+Braun group. There were no significant differences between uncut Roux-en-Y group and BII(+Braun group in median age (56.0 years vs. 56.5 years, P=0.757), gender (male/female, 52/29 vs. 46/12, P=0.054), history of abdominal surgery (yes/no, 10/71 vs. 4/54, P=0.293), neoadjuvant chemotherapy (yes/no, 21/60 vs. 11/47, P=0.336), BMI (thin/normal/overweight/obesity, 2/49/26/3 vs. 3/39/14/2, P=0.591), NRS 2002 score (1/2/3/4, 58/15/5/3 vs. 47/5/3/3, P=0.403), pathological stage (0/I(/II(/III(, 3/41/20/17 vs. 1/28/13/16, P=0.755), median tumor diameter in long axis (2.5 cm vs. 3.0 cm, P=0.278), median tumor diameter in short axis (2.0 cm vs. 2.0 cm, P=0.126) and some other clinical and pathological characteristics. There were no significant differences between uncut Roux-en-Y group and BII(+Braun group in morbidity of postoperative complication more severe than grade I([12.3% (10/81) vs. 17.2% (10/58), P=0.417], morbidity of anastomotic complication [1.2%(1/81) vs. 0, P=1.000] or hospitalization costs [(94000±14000) yuan vs.(95000±16000) yuan, P=0.895]. The median first time to liquid diet (57.1 hours vs. 70.8 hours, P=0.017) and median postoperative hospital stay (9 days vs. 11 days, P=0.003) of the patients in uncut Roux-en-Y group were shorter than those in BII(+Braun group. Laparoscopic assisted or totally laparoscopic uncut Roux-en-Y reconstruction after radical gastrectomy of distal gastric cancer is safe and feasible with better recovery than BII(+Braun reconstruction.

Random density matrices versus random evolution of open system

NASA Astrophysics Data System (ADS)

Pineda, Carlos; Seligman, Thomas H.

2015-10-01

We present and compare two families of ensembles of random density matrices. The first, static ensemble, is obtained foliating an unbiased ensemble of density matrices. As criterion we use fixed purity as the simplest example of a useful convex function. The second, dynamic ensemble, is inspired in random matrix models for decoherence where one evolves a separable pure state with a random Hamiltonian until a given value of purity in the central system is achieved. Several families of Hamiltonians, adequate for different physical situations, are studied. We focus on a two qubit central system, and obtain exact expressions for the static case. The ensemble displays a peak around Werner-like states, modulated by nodes on the degeneracies of the density matrices. For moderate and strong interactions good agreement between the static and the dynamic ensembles is found. Even in a model where one qubit does not interact with the environment excellent agreement is found, but only if there is maximal entanglement with the interacting one. The discussion is started recalling similar considerations for scattering theory. At the end, we comment on the reach of the results for other convex functions of the density matrix, and exemplify the situation with the von Neumann entropy.

Astronauts Alan Bean and Charles Conrad on Lunar Surface

NASA Technical Reports Server (NTRS)

1969-01-01

The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn Five launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what's known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Their lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. In this photograph, one of the astronauts on the Moon's surface is holding a container of lunar soil. The other astronaut is seen reflected in his helmet. Apollo 12 safely returned to Earth on November 24, 1969.

Saturn Apollo Program

NASA Image and Video Library

1969-07-20

This is a detailed view of the back side of Moon in the vicinity of Crater No. 308 taken during the Apollo 11 mission. Apollo 11, the first manned lunar mission, launched from The Kennedy Space Center, Florida via a Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. The 3-man crew aboard the flight consisted of Neil A. Armstrong, commander; Michael Collins, Command Module pilot; and Edwin E. Aldrin Jr., Lunar Module pilot. The Lunar Module (LM), named “Eagle, carrying astronauts Neil Armstrong and Edwin Aldrin, was the first crewed vehicle to land on the Moon. Meanwhile, astronaut Collins piloted the Command Module in a parking orbit around the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. The crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. The surface exploration was concluded in 2½ hours. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

The Sun in Time

NASA Technical Reports Server (NTRS)

Adams, Mitzi L.; Bero, Elizabeth; Sever, Thomas L.

1999-01-01

Leveraging funds from NASA's Initiative to Develop Education through Astronomy and Space Science (IDEAS) program, we combined the expertise of an archaeoastronomer, a solar scientist, and a teacher to trace humankind's view of the Sun and how that has changed, from the time of Stonehenge in about 1800 B.C.E., to the time of the Maya in 700 C.E., up to the modem era. Our program was aimed at middle-school students in an attempt to explain not only how science is done today, but how science has evolved from the observations of ancient societies. From these varied cultures, we touched on methods of observing the Sun, ideas of the composition of the Sun, and the relationship of the Sun to everyday life. Further, using the von Braun Astronomical Society's Planetarium in Huntsville, Alabama as a test-bed for the program, we illustrated concepts such as solstices, equinoxes, and local noon with approximately 800 eighth grade students from the local area. Our presentation to SEPA will include a description of NASA's IDEAS program and how to go about partnering with a NASA astronomer, some slides from our planetarium program and web-site, and some hands-on activities.

Entanglement classes of symmetric Werner states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyons, David W.; Walck, Scott N.

2011-10-15

The symmetric Werner states for n qubits, important in the study of quantum nonlocality and useful for applications in quantum information, have a surprisingly simple and elegant structure in terms of tensor products of Pauli matrices. Further, each of these states forms a unique local unitary equivalence class, that is, no two of these states are interconvertible by local unitary operations.

Attention please: evaluative priming effects in a valent/non-valent categorisation task (reply to Werner & Rothermund, 2013).

PubMed

Spruyt, Adriaan

2014-04-01

It has previously been argued (a) that automatic evaluative stimulus processing is dependent upon feature-specific attention allocation (FSAA) and (b) that evaluative priming effects can arise in the absence of dimensional overlap between the prime set and the response set. In opposition to these claims, Werner and Rothermund (2013) recently reported that they were unable to replicate the evaluative priming effect in a valent/non-valent categorisation task. In this manuscript, I report the results of a conceptual replication of the studies by Werner and Rothermund (2013). A clear-cut evaluative priming effect was found, thus supporting the initial claims about FSAA and dimensional overlap. An explanation for these divergent findings is discussed.

Biological and Genomic Differences of ERG Oncoprotein-Stratified Prostate Cancers from African and Caucasian Americans

DTIC Science & Technology

2014-10-01

Tomlins SA, Mudaliar KM, et al: Antibody-based detection of ERG rearrangement-positive prostate cancer. Neoplasia 12: 590-598, 2010. 8. Braun M, Goltz D...detection of ERG rearrangement-positive prostate cancer. Neoplasia 12: 590-598, 2010. 16. Braun M, Goltz D, Shaikhibrahim Z, et al: ERG protein

Saturn Apollo Program

NASA Image and Video Library

1969-11-23

Sitting on the lunar surface, this Solar Wind Spectrometer is measuring the energies of the particles that make up the solar wind. This was one of the instruments used during the Apollo 12 mission. The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. Apollo 12 safely returned to Earth on November 24, 1969.

BOOK REVIEW: Time, Quantum and Information

NASA Astrophysics Data System (ADS)

Turner, Leaf

2004-04-01

Time, Quantum and Information, a paean to Professor Carl Friedrich von Weizsäcker, commemorates his 90th birthday. The range of Professor Weizsäcker’s endeavours is an exhilarating example of what can be accomplished by one freely-soaring human spirit, who is at the same time a physicist, a philosopher, and a humanitarian. The editors, Lutz Castell and Otfried Ischebeck, have assembled an admirable collection of essays and articles written by Weizsäcker’s past students, collaborators, colleagues and acquaintances. Time, Quantum and Information offers the reader a panoply of unique insights into twentieth century science and history. Entangled with the stories about Weizsäcker’s influence on the lives of some of the contributors are discussions of the activities of German scientists during and following World War II, emphasizing their reluctance to work on atomic weapons following the war. By outlining Weizsäcker’s role in the early development of numerous tributaries of physical science, the book gives us a new glimpse into the origins of some of its disparate domains, such as nuclear physics, the physics of stellar nucleosynthesis, cosmic ray physics, fluid turbulence, and the formation of the solar system. We physicists have all studied Weizsäcker’s semi-empirical mass formula describing the binding energy of nuclei. We are aware too that both he and Hans Bethe independently discovered the nuclear cycles that provide stars with their enduring energy output. We have studied the Weizsäcker--Williams technique of calculating the bremsstrahlung of relativistic electrons. But how many of us know of Weizsäcker’s work in fluid turbulence that he, like Werner Heisenberg under whom he had earned his doctorate, pursued while holed up in Farm Hall? And how many of us are aware of his introduction of turbulent viscosity to account for the origin of planetary orbits, involving the migration of mass inwards and angular momentum outwards? Moreover, before finally turning his attention to philosophy in 1957, Weizsäcker became interested in nuclear fusion research and educated a generation of postwar German physicists in both plasma physics and astrophysics. Michael Frayn’s play `Copenhagen' has ignited worldwide interest in the mysterious meeting of Niels Bohr with Werner Heisenberg in September 1941. However, an article by R Lüst indicates that in 1951 Bohr enjoyed a friendly visit with Heisenberg in Göttingen. This 1941 meeting of Heisenberg and Bohr is discussed further in an article by Götz Neuneck, who also details the World War II and post-war research and interests of the Uranium Club, a group of 70--100 German physicists and chemists. Neuneck also discusses the resistance of individual scientists, such as Hahn, Heisenberg, and Bothe, to the Nazi regime. We learn that, unlike Wernher von Braun, no member of the Uranium Club was ever granted an audience with Hitler. After the war, German scientists renounced any role for German development of nuclear weapons in various manifestos, such as the Mainau and G\\"ottingen Declarations that were both influenced by Weizsäcker. Time, Quantum and Information contains much anecdotal material. Examples include a touching quotation in a letter from Edward Teller to Weizsäcker: `If I could share your religious belief, I would wish that you will one day come from a higher heaven and visit me in purgatory.' Another example, less complimentary, is a comment from Pauli after hearing from Weisskopf that Weizsäcker had made numerous errors in his habilitation thesis and realizing that Weizsäcker had accepted an offer from Peter Debye at Berlin: `The measure of sloppiness in Weizsäcker’s work exceeds altogether and by far the tolerable measure, and my pain of not having had him as an assistant has been alleviated by this.' Two-thirds of this compendium also explores the philosophical interests of Weizsäcker. This portion discusses his attempt to reconstruct quantum mechanics and build up a `theory of everything' based on his `ur' hypothesis. As stated by the mathematician G G Emch in this book, `Philosophers and physicists often fail to understand each other because they are speaking different languages which often happen to have the same words.' These articles will have value to readers interested in these areas. The inclusion of an index would have made the book much more useful. There are numerous minor typographical errors, the most amusing of which is the sign of the Coulomb energy of a uniform density sphere in the article by K v Meyenn. (The expression stated is -6(Ze)2/5R rather than the correct expression, 3(Ze)2/5R.) Another example is in the same article: when one looks for a reference to Jackson, #66, one finds instead a 1928 reference to Fermi! Despite such inconvenient quirks, this book is essential reading for anyone interested in Weizsäcker and his research, in twentieth-century physics and physicists, and in unique insights into German science during and immediately following World War II.

A forest transect of pine mountain, Kentucky: changes since E. Lucy Braun and chestnut blight

Treesearch

Tracy S. Hawkins

2006-01-01

In 1997, forest composition and structure were determined for Hi Lewis Pine Barrens State Nature Preserve, a 68-ha tract on the south slope of Pine Mountain, Harlan County, Kentucky. Data collected from 28 0.04-ha plots were used to delineate forest types. Percent canopy compositions were compared with those reported by Dr. E. Lucy Braun prior to the peak of chestnut...

Writing My Way to My Future | Poster

Cancer.gov

By Nathalie Walker, Guest Writer Editor’s note: This article is the second in a series describing one student’s perspective on her experiences as a Werner H. Kirsten student intern. “The future depends on what you do today.” Those wise words were spoken by Mahatma Gandhi. Before I started my Werner H. Kirsten (WHK) student internship, I did not know what I know now. I only

Translations on Environmental Quality, Number 156.

DTIC Science & Technology

1978-01-06

Needed Now, Editorial EASTERN EUROPE EAST GERMANY Water Pollutants Investigated (Heinrich Langmaack, Werner Winter; BAUERN-ECHO, 12/13 Nov 77) 5... INVESTIGATED East Berlin BAUERN-ECHO in German 12/13 Nov 77 p 8 /Article by Heinrich Langmaack and Werner Winter, Institute for Water Management...the occupation of the area, which BASA (the Bank of Amazonia ) have financed in 2 years, a total expenditure of about 6 billion cruzeiros. Each

Effect of two-qutrit entanglement on quantum speed limit time of a bipartite V-type open system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Behzadi, N., E-mail: n.behzadi@tabrizu.ac.ir; Ahansaz, B.; Ektesabi, A.

In the present paper, quantum speed limit (QSL) time of a bipartite V-type three-level atomic system under the effect of two-qutrit entanglement is investigated. Each party interacts with own independent reservoir. By considering two local unitarily equivalent Werner states and the Horodecki PPT state, as initial states, the QSL time is evaluated for each of them in the respective entangled regions. It is counterintuitively observed that the effect of entanglement on the QSL time driven from each of the initial Werner states are completely different when the degree of non-Markovianity is considerable. In addition, it is interesting that the effectmore » of entanglement of the non-equivalent Horodecki state on the calculated QSL time displays an intermediate behavior relative to the cases obtained for the Werner states.« less

Heinz Werner: His Life, Ideas, and Contributions to Developmental Psychology in the First Half of the 20th Century.

PubMed

Ostler, Teresa

2016-01-01

The author provides an overview of Heinz Werner's life and contributions to the field of developmental psychology during the first half of the 20th century. She focuses on his early work in Vienna and Munich as well as his tenure at the Psychological Institute in Hamburg, up through the time when he became a named Professor in Psychology at Clark University. Recognized as one of the founders of developmental psychology, Heinz Werner worked in the areas of perceptual development, comparative psychology, and symbol formation. Versatile in rigorous experimental methodologies, and in observational and phenomenological methodologies, Werner's approach to development stood in contrast to other approaches of development, both past and current. For Werner, development was a heuristic, a way of looking at processes in a variety of domains, including ontogeny, phylogeny, microgenesis, biology, developmental psychopathology, neuropsychology, and comparative psychology. Werner viewed development as proceeding from a state of relative globality and lack of differentiation to a state of increasing differentiation, articulation, and hierarchical integration, but he also stressed that individuals can function at different developmental levels under different times and conditions. Werner's holistic, organismic, comparative, and contextual approach to development transcended interdisciplinary boundaries, allowing him to study the interrelatedness between thought, language, feeling, perception, and culture.

Synthesis and Characterization of Silyldichloramines, Their Reactions with F- Ions, Stability of N2CI2 and NCI2(-), and Formation of NCI3 (Postprint)

DTIC Science & Technology

2007-01-01

S. Can. J. Chem. 1987, 65, 88. (23) Werner, H. J.; Knowles, P. J.; Amos, R. D.; Bernhardsson, A.; Berning, A.; Celani, P.; Cooper, D. L.; Deegan , M. J...Phys. Chem. 1988, 92, 3033. (25) Knowles, P. J.; Hampel, C.; Werner, H. J. J. Chem. Phys. 1994, 99, 5219. (26) Deegan , M. J. O.; Knowles, P. J. Chem

Quantum information transmission in the quantum wireless multihop network based on Werner state

NASA Astrophysics Data System (ADS)

Shi, Li-Hui; Yu, Xu-Tao; Cai, Xiao-Fei; Gong, Yan-Xiao; Zhang, Zai-Chen

2015-05-01

Many previous studies about teleportation are based on pure state. Study of quantum channel as mixed state is more realistic but complicated as pure states degenerate into mixed states by interaction with environment, and the Werner state plays an important role in the study of the mixed state. In this paper, the quantum wireless multihop network is proposed and the information is transmitted hop by hop through teleportation. We deduce a specific expression of the recovered state not only after one-hop teleportation but also across multiple intermediate nodes based on Werner state in a quantum wireless multihop network. We also obtain the fidelity of multihop teleportation. Project supported by the Prospective Future Network Project of Jiangsu Province, China (Grant No. BY2013095-1-18) and the Independent Project of State Key Laboratory of Millimeter Waves (Grant No. Z201504).

Response to formal comment on Myhrvold (2016) submitted by Griebeler and Werner (2017)

PubMed Central

2018-01-01

Griebeler and Werner offer a formal comment on Myhrvold, 2016 defending the conclusions of Werner and Griebeler, 2014. Although the comment criticizes several aspects of methodology in Myhrvold, 2016, all three papers concur on a key conclusion: the metabolism of extant endotherms and ectotherms cannot be reliably classified using growth-rate allometry, because the growth rates of extant endotherms and ectotherms overlap. A key point of disagreement is that the 2014 paper concluded that despite this general case, one can nevertheless classify dinosaurs as ectotherms from their growth rate allometry. The 2014 conclusion is based on two factors: the assertion (made without any supporting arguments) that the comparison with dinosaurs must be restricted only to extant sauropsids, ignoring other vertebrate groups, and that extant sauropsid endotherm and ectotherm growth rates in a data set studied in the 2014 work do not overlap. The Griebeler and Werner formal comment presents their first arguments in support of the restriction proposition. In this response I show that this restriction is unsupported by established principles of phylogenetic comparison. In addition, I show that the data set studied in their 2014 work does show overlap, and that this is visible in one of its figures. I explain how either point effectively invalidates the conclusion of their 2014 paper. I also address the other methodological criticisms of Myhrvold 2016, and find them unsupported. PMID:29489880

The Determination of User Information Requirements during the Development of Management Information Systems.

DTIC Science & Technology

1983-06-01

Werner , Greenburg, and Goldberg [Ref. 51 1 for determining the p information needs of an outpatient clinic) tries to make up for this difficulty. Rather...observed to determine what information is being used and how it is being used. Werner et al. point out that, "The behavior of the physician does not...the " Heisenberg Uncertainty Principle," namely: ...any system development activity inevitably changes the environment out of which tte need for the

An Act of Scientific Creativity: Meitner, Frisch, and Nuclear Fission

NASA Astrophysics Data System (ADS)

Stuewer, Roger H.

2002-04-01

The dominant event that lay in the background to Werner Heisenberg's fateful meeting with Niels Bohr in occupied Copenhagen in September 1941 was the discovery and interpretation of nuclear fission three years earlier. Michael Frayn has explored that meeting in his play "Copenhagen" in an act of extraordinary literary creativity. In this talk I will explore Lise Meitner's and Otto Robert Frisch's interpretation of nuclear fission as an act of extraordinary scientific creativity. My aim is to understand historically how it was possible for Meitner and Frisch, and only Meitner and Frisch, to arrive at their interpretation as they talked and walked in the snow in the small Swedish village of Kungälv over the Christmas holidays in December 1938. This will require us to examine the history of the liquid-drop model of the nucleus over the preceding decade, from George Gamow's conception of that model in 1928, through Heisenberg and Carl Friedrich von Weizsäcker's extension of it between 1933 and 1936, and finally through Bohr's use of it in his theory of the compound nucleus between 1936 and 1938. We will see how Meitner and Frisch combined their different knowledge of these developments creatively to arrive at their momentous interpretation of nuclear fission.

Fragmentation inside atomic cooling haloes exposed to Lyman-Werner radiation

NASA Astrophysics Data System (ADS)

Regan, John A.; Downes, Turlough P.

2018-04-01

Supermassive stars born in pristine environments in the early Universe hold the promise of being the seeds for the supermassive black holes observed as high redshift quasars shortly after the epoch of reionisation. H2 suppression is thought to be crucial in order to negate normal Population III star formation and allow high accretion rates to drive the formation of supermassive stars. Only in the cases where vigorous fragmentation is avoided will a monolithic collapse be successful, giving rise to a single massive central object. We investigate the number of fragmentation sites formed in collapsing atomic cooling haloes subject to various levels of background Lyman-Werner flux. The background Lyman-Werner flux manipulates the chemical properties of the gas in the collapsing halo by destroying H2. We find that only when the collapsing gas cloud shifts from the molecular to the atomic cooling regime is the degree of fragmentation suppressed. In our particular case, we find that this occurs above a critical Lyman-Werner background of J ˜ 10 J21. The important criterion being the transition to the atomic cooling regime rather than the actual value of J, which will vary locally. Once the temperature of the gas exceeds T ≳ 104 K and the gas transitions to atomic line cooling, then vigorous fragmentation is strongly suppressed.

Environmental Remediation to Address Childhood Lead Poisoning Epidemic due to Artisanal Gold Mining in Zamfara, Nigeria

PubMed Central

Tirima, Simba; Bartrem, Casey; von Lindern, Ian; von Braun, Margrit; Lind, Douglas; Anka, Shehu Mohammed; Abdullahi, Aishat

2016-01-01

Background: From 2010 through 2013, integrated health and environmental responses addressed an unprecedented epidemic lead poisoning in Zamfara State, northern Nigeria. Artisanal gold mining caused widespread contamination resulting in the deaths of > 400 children. Socioeconomic, logistic, and security challenges required remediation and medical protocols within the context of local resources, labor practices, and cultural traditions. Objectives: Our aim was to implement emergency environmental remediation to abate exposures to 17,000 lead poisoned villagers, to facilitate chelation treatment of children ≤ 5 years old, and to establish local technical capacity and lead health advocacy programs to prevent future disasters. Methods: U.S. hazardous waste removal protocols were modified to accommodate local agricultural practices. Remediation was conducted over 4 years in three phases, progressing from an emergency response by international personnel to comprehensive cleanup funded and accomplished by the Nigerian government. Results: More than 27,000 m3 of contaminated soils and mining waste were removed from 820 residences and ore processing areas in eight villages, largely by hand labor, and disposed in constructed landfills. Excavated areas were capped with clean soils (≤ 25 mg/kg lead), decreasing soil lead concentrations by 89%, and 2,349 children received chelation treatment. Pre-chelation geometric mean blood lead levels for children ≤ 5 years old decreased from 149 μg/dL to 15 μg/dL over the 4-year remedial program. Conclusions: The unprecedented outbreak and response demonstrate that, given sufficient political will and modest investment, the world’s most challenging environmental health crises can be addressed by adapting proven response protocols to the capabilities of host countries. Citation: Tirima S, Bartrem C, von Lindern I, von Braun M, Lind D, Anka SM, Abdullahi A. 2016. Environmental remediation to address childhood lead poisoning epidemic due to artisanal gold mining in Zamfara, Nigeria. Environ Health Perspect 124:1471–1478; http://dx.doi.org/10.1289/ehp.1510145 PMID:26745642

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via a Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module pilot; and Edwin E. Aldrin Jr., Lunar Module pilot. The Command Module (CM), piloted by Michael Collins remained in a parking orbit around the Moon while the Lunar Module (LM), named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. The surface exploration was concluded in 2½ hours, in which the crew collected 47 pounds of lunar surface material for analysis back on Earth. Upon splash down in the Pacific Ocean, Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was taken to safety aboard the USS Hornet, where they were quartered in a mobile quarantine facility. Shown here is the Apollo 11 crew inside the quarantine facility. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Environmental Remediation to Address Childhood Lead Poisoning Epidemic due to Artisanal Gold Mining in Zamfara, Nigeria.

PubMed

Tirima, Simba; Bartrem, Casey; von Lindern, Ian; von Braun, Margrit; Lind, Douglas; Anka, Shehu Mohammed; Abdullahi, Aishat

2016-09-01

From 2010 through 2013, integrated health and environmental responses addressed an unprecedented epidemic lead poisoning in Zamfara State, northern Nigeria. Artisanal gold mining caused widespread contamination resulting in the deaths of > 400 children. Socioeconomic, logistic, and security challenges required remediation and medical protocols within the context of local resources, labor practices, and cultural traditions. Our aim was to implement emergency environmental remediation to abate exposures to 17,000 lead poisoned villagers, to facilitate chelation treatment of children ≤ 5 years old, and to establish local technical capacity and lead health advocacy programs to prevent future disasters. U.S. hazardous waste removal protocols were modified to accommodate local agricultural practices. Remediation was conducted over 4 years in three phases, progressing from an emergency response by international personnel to comprehensive cleanup funded and accomplished by the Nigerian government. More than 27,000 m3 of contaminated soils and mining waste were removed from 820 residences and ore processing areas in eight villages, largely by hand labor, and disposed in constructed landfills. Excavated areas were capped with clean soils (≤ 25 mg/kg lead), decreasing soil lead concentrations by 89%, and 2,349 children received chelation treatment. Pre-chelation geometric mean blood lead levels for children ≤ 5 years old decreased from 149 μg/dL to 15 μg/dL over the 4-year remedial program. The unprecedented outbreak and response demonstrate that, given sufficient political will and modest investment, the world's most challenging environmental health crises can be addressed by adapting proven response protocols to the capabilities of host countries. Tirima S, Bartrem C, von Lindern I, von Braun M, Lind D, Anka SM, Abdullahi A. 2016. Environmental remediation to address childhood lead poisoning epidemic due to artisanal gold mining in Zamfara, Nigeria. Environ Health Perspect 124:1471-1478; http://dx.doi.org/10.1289/ehp.1510145.

Werner-Wheeler mass tensor for fusionlike configuration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gherghescu, R.A.; Poenaru, D.N.

2005-08-01

The Werner-Wheeler approach is used to calculate the components of the mass tensor for a binary configuration of two intersected spheroids. Four free coordinates form the deformation space: the small semiaxis of the projectile, the two semiaxis ratios of the spheroids, and the distance between centers. A correction term is also calculated, due to the center of mass motion. Final results are presented for the fusion channel {sup 54}Cr+{sup 240}Pu, and all possible couplings are analyzed.

Saturn Apollo Program

NASA Image and Video Library

1969-11-24

Aboard the recovery ship, USS Hornet, Apollo 12 astronauts wave to the crowd as they enter the mobile quarantine facility. The recovery operation took place in the Pacific Ocean after the splashdown of the Command Module capsule. Navy para-rescue men recovered the capsule housing the 3-man Apollo 12 crew. The second manned lunar landing mission, Apollo 12 launched from launch pad 39-A at Kennedy Space Center in Florida on November 14, 1969 via a Saturn V launch vehicle. The Saturn V was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard Apollo 12 was a crew of three astronauts: Alan L. Bean, pilot of the Lunar Module (LM), Intrepid; Richard Gordon, pilot of the Command Module (CM), Yankee Clipper; and Spacecraft Commander Charles Conrad. The LM, Intrepid, landed astronauts Conrad and Bean on the lunar surface in what’s known as the Ocean of Storms while astronaut Richard Gordon piloted the CM, Yankee Clipper, in a parking orbit around the Moon. Lunar soil activities included the deployment of the Apollo Lunar Surface Experiments Package (ALSEP), finding the unmanned Surveyor 3 that landed on the Moon on April 19, 1967, and collecting 75 pounds (34 kilograms) of rock samples. Apollo 12 safely returned to Earth on November 24, 1969.

II: Through the Western Part of the City: Charlottenburg

NASA Astrophysics Data System (ADS)

Hoffmann, Dieter

Until 1920 the city we now call Berlin was a collection of independent towns and villages — among them Charlottenburg, which was one of the most important and was the proud sister of Berlin, Prussia’s and Germany’s capital, where the wealthy and innovative bourgeoisie lived. Werner von Siemens, Germany’s pioneer in the modern electrical industry, was a prime example of that elite. His castle-like villa was located not far from today’s Ernst-Reuter-Platz at Otto-Suhr-Allee 10-16, and important parts of his enterprise expanded into the “meadows outside of Charlottenburg” during the second half of the 19th century. It was no accident that the efforts to unite Berlin’s two colleges for trade and construction (both founded around 1800) led to the foundation of a modern Technical College in Charlottenburg in 1879, today’s Technical University of Berlin. Its magnificent main building (figure 1), which was opened in 1882 by the German Emperor, was an expression of the great self-confidence of this new institution of higher learning and of Charlottenburg’s bourgeoisie. Although large parts of the building were destroyed by bombs during World War II, you can still get an impression of its monumentality from what survived at number 135 Strasse des 17. Juni.

Oxygen Breathing Accelerates Decompression from Saturation at 40 msw in 70-kg Swine

DTIC Science & Technology

2010-07-01

2010 0 2 AFfER A DEEP SATURATION DIVE-PETERSEN ET AL. REFERENCES 1. Bain SA, Tmg J, Simeonovic CJ, Wilson JO. Technique of venous catheterization ...was catheterized with a 16-gauge by 20.3-cm single lumen catheter (Braun Certofix; B. Braun Medical Inc., Bethlehem, PA) via the modified Seldinger...respiratory distress, as evidenced by open-mouthed, labored breathing, central cyanosis, or the production of frothy white sputum. The onset of se- vere

Case Report: A Rare Cause of Complicated Urinary Tract Infection in a Woman with Herlyn-Werner-Wunderlich Syndrome.

PubMed

Tsai, Jun-Li; Tsai, Shang-Feng

2016-11-01

Urinary tract infection is a common disease in the general population. However, in patients with frequent urinary tract infection, it is important to determine any treatable cause to avoid recurrence. Herlyn-Werner-Wunderlich syndrome or OHVIRA syndrome is a very rare congenital anomaly with uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. The earliest presentation of this syndrome is hematocolpos that develops during menstruation and results in dysmenorrhea and a pelvic mass shortly after menarche. Herein, we report a patient with Herlyn-Werner-Wunderlich syndrome manifested with unusual symptoms, delayed onset and without surgery. The unique point of this patient is the partial obstruction of cervico-vaginal junction. Early diagnosis and timely treatment of OHVIRA syndrome can prevent long-term complications, such as recurrent urinary tract infection and infertility. A high index of suspicion is required, even though OHVIRA syndrome is extremely rare and may have an atypical presentation.

Response to formal comment on Myhrvold (2016) submitted by Griebeler and Werner (2017).

PubMed

Myhrvold, Nathan P

2018-01-01

Griebeler and Werner offer a formal comment on Myhrvold, 2016 defending the conclusions of Werner and Griebeler, 2014. Although the comment criticizes several aspects of methodology in Myhrvold, 2016, all three papers concur on a key conclusion: the metabolism of extant endotherms and ectotherms cannot be reliably classified using growth-rate allometry, because the growth rates of extant endotherms and ectotherms overlap. A key point of disagreement is that the 2014 paper concluded that despite this general case, one can nevertheless classify dinosaurs as ectotherms from their growth rate allometry. The 2014 conclusion is based on two factors: the assertion (made without any supporting arguments) that the comparison with dinosaurs must be restricted only to extant sauropsids, ignoring other vertebrate groups, and that extant sauropsid endotherm and ectotherm growth rates in a data set studied in the 2014 work do not overlap. The Griebeler and Werner formal comment presents their first arguments in support of the restriction proposition. In this response I show that this restriction is unsupported by established principles of phylogenetic comparison. In addition, I show that the data set studied in their 2014 work does show overlap, and that this is visible in one of its figures. I explain how either point effectively invalidates the conclusion of their 2014 paper. I also address the other methodological criticisms of Myhrvold 2016, and find them unsupported.

Nonseparable Werner states in spontaneous parametric down-conversion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caminati, Marco; De Martini, Francesco; Perris, Riccardo

2006-03-15

The multiphoton states generated by high-gain spontaneous parametric down-conversion (SPDC) in the presence of large losses are investigated theoretically and experimentally. The explicit form for the two-photon output state has been found to exhibit a Werner structure very resilient to losses for any value of the nonlinear gain parameter g. The theoretical results are found to be in agreement with experimental data obtained by 'entanglement witness' methods and by the quantum tomography of the state generated by a high-g SPDC.

Introducing Defects in 3D Photonic Crystals: State of the Art

DTIC Science & Technology

2006-01-01

the art 5. FUNDING NUMBERS DAAD190310227 6. AUTHOR(S) P. V. Braun, S. A. Pruzinsky, and F . Garcia-Santamaria 7...microscopy image of a y-splitter defect formed through two-photon polymerization within a CC. – [*] Prof. P. V. Braun, Dr. S. A. Rinne, Dr. F . García...John, O. Toader, Phys. Rev. Lett. 2003, 90, 3901. [15] T. F . Krauss, R. M. De La Rue, S. Brand, Nature 1996, 383, 699. [16] R. D. Meade, K. D. Brommer

Accelerated Decompression from Saturation at 132 Feet of Sea Water With Isobaric oxygenation at 60 Feet of Sea Water

DTIC Science & Technology

2009-02-01

catheterized with an external jugular catheter via the Seldinger technique and allowed to recover. Subjects were exposed to 132 feet of seawater (fsw) in...the external jugular vein of the animal was catheterized with a 16 gauge by 20.3 cm single lumen catheter (Braun Certofix; B. Braun Medical Inc... central cyanosis or the production of frothy white sputum. The onset of severe DCS (neurological or cardio-pulmonary dysfunction) and all behavioral

Species concepts in Cercospora: spotting the weeds among the roses

PubMed Central

Groenewald, J.Z.; Nakashima, C.; Nishikawa, J.; Shin, H.-D.; Park, J.-H.; Jama, A.N.; Groenewald, M.; Braun, U.; Crous, P.W.

2013-01-01

The genus Cercospora contains numerous important plant pathogenic fungi from a diverse range of hosts. Most species of Cercospora are known only from their morphological characters in vivo. Although the genus contains more than 5 000 names, very few cultures and associated DNA sequence data are available. In this study, 360 Cercospora isolates, obtained from 161 host species, 49 host families and 39 countries, were used to compile a molecular phylogeny. Partial sequences were derived from the internal transcribed spacer regions and intervening 5.8S nrRNA, actin, calmodulin, histone H3 and translation elongation factor 1-alpha genes. The resulting phylogenetic clades were evaluated for application of existing species names and five novel species are introduced. Eleven species are epi-, lecto- or neotypified in this study. Although existing species names were available for several clades, it was not always possible to apply North American or European names to African or Asian strains and vice versa. Some species were found to be limited to a specific host genus, whereas others were isolated from a wide host range. No single locus was found to be the ideal DNA barcode gene for the genus, and species identification needs to be based on a combination of gene loci and morphological characters. Additional primers were developed to supplement those previously published for amplification of the loci used in this study. Taxonomic novelties: New species - Cercospora coniogrammes Crous & R.G. Shivas, Cercospora delaireae C. Nakash., Crous, U. Braun & H.D. Shin, Cercospora euphorbiae-sieboldianae C. Nakash., Crous, U. Braun & H.D. Shin, Cercospora pileicola C. Nakash., Crous, U. Braun & H.D. Shin, Cercospora vignigena C. Nakash., Crous, U. Braun & H.D. Shin. Typifications: epitypifications - Cercospora alchemillicola U. Braun & C.F. Hill, Cercospora althaeina Sacc., Cercospora armoraciae Sacc., Cercospora corchori Sawada, Cercospora mercurialis Pass., Cercospora olivascens Sacc., Cercospora violae Sacc.; neotypifications - Cercospora fagopyri N. Nakata & S. Takim., Cercospora sojina Hara. PMID:24014899

Entanglement cost under positive-partial-transpose-preserving operations.

PubMed

Audenaert, K; Plenio, M B; Eisert, J

2003-01-17

We study the entanglement cost under quantum operations preserving the positivity of the partial transpose (PPT operations). We demonstrate that this cost is directly related to the logarithmic negativity, thereby providing the operational interpretation for this entanglement measure. As examples we discuss general Werner states and arbitrary bipartite Gaussian states. Then we prove that for the antisymmetric Werner state PPT cost and PPT entanglement of distillation coincide. This is the first example of a truly mixed state for which entanglement manipulation is asymptotically reversible, which points towards a unique entanglement measure under PPT operations.

Selective Security Cooperation: A Proposed Index to Measure the Value of Partners and Focus International Engagement

DTIC Science & Technology

2014-02-13

United States Air Force Academy in 1993. As an Air Force pilot, he has flown the T-37C Tweet, the T-38A Talon and the U - 2S Dragon Lady. He served as... property of the United States government. iii Biography Lieutenant Colonel A.J. Werner is a student at the Air War College at Maxwell Air...speaks Bulgarian and German. Colonel Werner has flown over 100 combat missions and 4,200 hours in US and Bulgarian Air Force aircraft . In addition

The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells.

PubMed

Bagley, Mark C; Dwyer, Jessica E; Baashen, Mohammed; Dix, Matthew C; Murziani, Paola G S; Rokicki, Michal J; Kipling, David; Davis, Terence

2016-01-21

Microwave-assisted synthesis of the pyrazolyl ketone p38 MAPK inhibitor RO3201195 in 7 steps and 15% overall yield, and the comparison of its effect upon the proliferation of Werner Syndrome cells with a library of pyrazolyl ketones, strengthens the evidence that p38 MAPK inhibition plays a critical role in modulating premature cellular senescence in this progeroid syndrome and the reversal of accelerated ageing observed in vitro on treatment with SB203580.

Quantum nondemolition measurement of the Werner state

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jin Jiasen; Yu Changshui; Pei Pei

2010-10-15

We propose a theoretical scheme of quantum nondemolition measurement of two-qubit Werner state. We discuss our scheme with the two qubits restricted in a local place and then extend the scheme to the case in which two qubits are separated. We also consider the experimental realization of our scheme based on cavity quantum electrodynamics. It is very interesting that our scheme is robust against the dissipative effects introduced by the probe process. We also give a brief interpretation of our scheme finally.

Computational Identification and Analysis of Signaling Subnetworks with Distinct Functional Roles in the Regulation of TNF Production

DTIC Science & Technology

2016-01-04

extract four distinct quantitative features of response timing and intensity: the trajectory peak height, the peak time, the area under the curve, and...J., 2007, 21, 325–332. 16 S. L. Werner, J. D. Kearns, V. Zadorozhnaya, C. Lynch, E. O’Dea, M. P. Boldin , A. Ma, D. Baltimore and A. Hoffmann, Genes...Werner, J. D. Kearns, V. Zadorozhnaya, C. Lynch, E. O’Dea, M. P. Boldin , A. Ma, D. Baltimore and A. Hoffmann, Genes Dev., 2008, 22, 2093–2101. 58 J

Women at Altitude: Effects of Menstrual Cycle Phase and Alpha-Adrenergic Blockade on High Altitude Acclimatization

DTIC Science & Technology

1999-10-01

Humans. For Volume 26 of Exercise and Sport Sciences Reviews. Ed.: John 0. Holloszy. Chapter 4, 91-116, 1998. Mawson , J . T ., B. Braun, P. B. Rock, L. G...Butterfield, J.T. Mawson , S. Zamudio, L.G. Moore. Catecholamine response during 12 days of high-altitude exposure (4,300 m) in women. J Appl Physiol 84:1151...7, 1998. Muza, S.R., P.B. Rock, C. S. Fulco, S. Zumudio, B. Braun, J . T . Reeves, G.E. Butterfield, and L. G. Moore. Influence of menstrual cycle phase

Design of the central region in the Gustaf Werner cyclotron at the Uppsala university

NASA Astrophysics Data System (ADS)

Toprek, Dragan; Reistad, Dag; Lundstrom, Bengt; Wessman, Dan

2002-07-01

This paper describes the design of the central region in the Gustaf Werner cyclotron for h=1, 2 and 3 modes of acceleration. The electric field distribution in the inflector and in the four acceleration gaps has been numerically calculated from an electric potential map produced by the program RELAX3D. The geometry of the central region has been tested with the computations of orbits carried out by means of the computer code CYCLONE. The optical properties of the spiral inflector and the central region were studied by using the programs CASINO and CYCLONE, respectively.

[Werner Leibbrand as psychiatric opponent of National Socialism].

PubMed

Seidel, R

2013-09-01

The psychiatrist and medical historian Werner Leibbrand resigned from the Berlin Medical Association after the seizure of power in protest against the exclusion of Jewish colleagues and lost both the license to practice as well as his professional position in the public health service. After the end of the war the American military authorities appointed him as expert witness for the prosecution in the Nürnberg Doctors Trial. In addition to a biographical review, Leibbrand's resolute although still undisputed attitude as ethical expert in the trials will be roughly outlined.

U.S. President Richard Milhous Nixon Watches Apollo 11 Recovery

NASA Technical Reports Server (NTRS)

1969-01-01

U.S. President Richard Milhous Nixon, aboard the U.S.S. Hornet aircraft carrier, used binoculars to watch the Apollo 11 Lunar Mission recovery. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF) for 21 days post mission. The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Saturn Apollo Program

NASA Image and Video Library

1969-07-20

This is a close-up view of an astronaut’s footprint in the lunar soil, photographed by a 70 mm lunar surface camera during the Apollo 11 lunar surface extravehicular activity. The first manned lunar mission, the Apollo 11 launched aboard a Saturn V launch vehicle from the Kennedy Space Center, Florida on July 16, 1969 and safely returned to Earth on July 24, 1969. The 3-man crew aboard the flight consisted of Neil A, Armstrong, mission commander; Edwin E. Aldrin, Jr., Lunar Module Pilot; and Michael Collins, Command Module pilot. The LM landed on the moon’s surface on July 20, 1969 in the region known as Mare Tranquilitatis (the Sea of Tranquility). Armstrong was the first human to ever stand on the lunar surface. As he stepped off the LM, Armstrong proclaimed, “That’s one small step for man, one giant leap for mankind”. He was followed by Edwin (Buzz) Aldrin, describing the lunar surface as Magnificent desolation. Astronaut Collins piloted the Command Module in a parking orbit around the Moon. The crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. The surface exploration was concluded in 2½ hours. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. von Braun.

The Michoud Assembly Facility (MAF)

NASA Technical Reports Server (NTRS)

2000-01-01

NASA's Michoud Assembly Facility, located in eastern New Orleans, Louisiana, is an 832 acre site that is a government-owned, contractor-operated component of the George C. Marshall Space Flight Center (MSFC). The facility was acquired by NASA in 1961 at the recommendation of Dr. Wernher von Braun and his rocket team in Huntsville Alabama. The cavernous plant served as the assembly facility for the Saturn launch vehicles and most recently the external tank (ET) used for the Space Shuttle Program. The facility features one of the world's biggest manufacturing plants with 43 acres under one roof and a port with deep-water access for the transportation of large space structures. When completed, space hardware is towed on a barge across the Gulf of Mexico, around Florida and up to Kennedy Space Center. The original tract of land was part of a 34,500 acre French Royal land grant to local merchant, Gilbert Antoine de St. Maxent in 1763. Later, the land was acquired by French transplant Antoine Michoud, the son of Napoleon's Administrator of Domains, who moved to the city in 1827. Michoud operated a sugar cane plantation and refinery on the site until his death in 1863. His heirs continued operating the refinery and kept the original St. Maxent estate intact into the 20th century. Visible on the right, is one of two brick smokestacks from the original refinery that still stand before the Michoud facility today.

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

U.S. President Richard Milhous Nixon, aboard the U.S.S. Hornet aircraft carrier, used binoculars to watch the Apollo 11 Lunar Mission recovery. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF) for 21 days post mission. The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

Dr. Thomas Paine, NASA administrator (left) and U.S. President Richard Milhous Nixon wait aboard the recovery ship, the U.S.S. Hornet, for splashdown of the Apollo 11 in the Pacific Ocean. Navy para-rescue men recovered the capsule housing the 3-man crew. The crew was taken to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

NASA Administrator Paine and U.S. President Richard Milhous Nixon Await Apollo 11 Splashdown

NASA Technical Reports Server (NTRS)

1969-01-01

Dr. Thomas Paine, NASA administrator (left) and U.S. President Richard Milhous Nixon wait aboard the recovery ship, the U.S.S. Hornet, for splashdown of the Apollo 11 in the Pacific Ocean. Navy para-rescue men recovered the capsule housing the 3-man crew. The crew was taken to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Around Marshall

NASA Image and Video Library

2000-09-09

NASA's Michoud Assembly Facility, located in eastern New Orleans, Louisiana, is an 832 acre site that is a government-owned, contractor-operated component of the George C. Marshall Space Flight Center (MSFC). The facility was acquired by NASA in 1961 at the recommendation of Dr. Wernher von Braun and his rocket team in Huntsville Alabama. The cavernous plant served as the assembly facility for the Saturn launch vehicles and most recently the external tank (ET) used for the Space Shuttle Program. The facility features one of the world's biggest manufacturing plants with 43 acres under one roof and a port with deep-water access for the transportation of large space structures. When completed, space hardware is towed on a barge across the Gulf of Mexico, around Florida and up to Kennedy Space Center. The original tract of land was part of a 34,500 acre French Royal land grant to local merchant, Gilbert Antoine de St. Maxent in 1763. Later, the land was acquired by French transplant Antoine Michoud, the son of Napoleon's Administrator of Domains, who moved to the city in 1827. Michoud operated a sugar cane plantation and refinery on the site until his death in 1863. His heirs continued operating the refinery and kept the original St. Maxent estate intact into the 20th century. Two brick smokestacks from the original refinery still stand before the Michoud facility today.

WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects

PubMed Central

Yokote, Koutaro; Chanprasert, Sirisak; Lee, Lin; Eirich, Katharina; Takemoto, Minoru; Watanabe, Aki; Koizumi, Naoko; Lessel, Davor; Mori, Takayasu; Hisama, Fuki M.; Ladd, Paula D.; Angle, Brad; Baris, Hagit; Cefle, Kivanc; Palanduz, Sukru; Ozturk, Sukru; Chateau, Antoinette; Deguchi, Kentaro; Easwar, T.K.M; Federico, Antonio; Fox, Amy; Grebe, Theresa A.; Hay, Beverly; Nampoothiri, Sheela; Seiter, Karen; Streeten, Elizabeth; Piña-Aguilar, Raul E.; Poke, Gemma; Poot, Martin; Posmyk, Renata; Martin, George M.; Kubisch, Christian; Schindler, Detlev; Oshima, Junko

2017-01-01

Werner syndrome (WS) is a rare autosomal recessive disorder characterized by a constellation of adult onset phenotypes consistent with an acceleration of intrinsic biological aging. It is caused by pathogenic variants in the WRN gene, which encodes a multifunctional nuclear protein with exonuclease and helicase activities. WRN protein is thought to be involved in optimization of various aspects of DNA metabolism, including DNA repair, recombination, replication, and transcription. In this update, we summarize a total of 83 different WRN mutations, including eight previously unpublished mutations identified by the International Registry of Werner Syndrome (Seattle, WA) and the Japanese Werner Consortium (Chiba, Japan), as well as 75 mutations already reported in the literature. The Seattle International Registry recruits patients from all over the world to investigate genetic causes of a wide variety of progeroid syndromes in order to contribute to the knowledge of basic mechanisms of human aging. Given the unusually high prevalence of WS patients and heterozygous carriers in Japan, the major goal of the Japanese Consortium is to develop effective therapies and to establish management guidelines for WS patients in Japan and elsewhere. This review will also discuss potential translational approaches to this disorder, including those currently under investigation. PMID:27667302

Sensitivity analysis of a variability in rock thermal conductivity concerning implications on the thermal evolution of the Brazilian South Atlantic passive continental margin

NASA Astrophysics Data System (ADS)

Stippich, Christian; Krob, Florian; Glasmacher, Ulrich Anton; Hackspacher, Peter Christian

2017-04-01

The aim of the research is to quantify the long-term evolution of the western South Atlantic passive continental margin (SAPCM) in SE-Brazil. Excellent onshore outcrop conditions and extensive pre-rift to post-rift archives between São Paulo and Laguna allow a high precision quantification of exhumation, and rock uplift rates, influencing physical parameters, long-term acting forces, and process-response systems. The research integrates published (Karl et al., 2013) and partly published thermochronological data from Brazil, and test lately published new concepts on causes of long-term landscape and lithospheric evolution in southern Brazil. Six distinct lithospheric blocks (Laguna, Florianópolis, Curitiba, Ilha Comprida, Peruibe and Santos), which are separated by fracture zones (Karl et al., 2013) are characterized by individual thermochronological age spectra. Furthermore, the thermal evolution derived by numerical modeling indicates variable post-rift exhumation histories of these blocks. In this context, we will provide information on the causes for the complex exhumation history of the Florianópolis, and adjacent blocks. Following up on our latest publication (Braun et al., 2016) regarding the effect of variability in rock thermal conductivity on exhumation rate estimates we performed a sensitivity analysis to quantify the effect of a differentiated lithospheric crust on the thermal evolution of the Florianópolis block versus exhumation rates estimated from modelling a lithospheric uniform crustal block. The long-term landscape evolution models with process rates were computed with the software code PECUBE (Braun, 2003; Braun et al., 2012). Testing model solutions obtained for a multidimensional parameter space against the real thermochronological and geomorphological data set, the most likely combinations of parameters, values, and rates can be constrained. References Braun, J., 2003. Pecube: A new finite element code to solve the 3D heat transport equation including the effects of a time-varying, finite amplitude surface topography. Computers and Geosciences, v.29, pp.787-794. Braun, J., Stippich, C., Glasmacher, U. A., 2016. The effect of variability in rock thermal conductivity on exhumation rate estimates from thermochronological data. Tectonophysics, v.690, pp.288-297 Braun, J., van der Beek, P., Valla, P., Robert, X., Herman, F., Goltzbacj, C., Pedersen, V., Perry, C., Simon-Labric, T., Prigent, C., 2012. Quantifying rates of landscape evolution and tectonic processes by thermochronology and numerical modeling of crustal heat transport using PECUBE. Tectonophysics, v.524-525, pp.1-28. Karl, M., Glasmacher, U.A., Kollenz, S., Franco-Magalhaes, A.O.B., Stockli, D.F., Hackspacher, P., 2013. Evolution of the South Atlantic passive continental margin in southern Brazil derived from zircon and apatite (U-Th-Sm)/He and fission-track data. Tectonophysics, Volume 604, Pages 224-244.

Quality and Safety Matter

NASA Astrophysics Data System (ADS)

Manha, William D.

2010-09-01

One to the expressions for the most demanding quality was made by a well-known rocket scientist, for which this center was named, Dr. Wernher Von Braun in the Foreword of a book about the design of rocket engines that was first published by NASA in 1967: “Success in space demands perfection. Many of the brilliant achievements made in this vast, austere environment seem almost miraculous. Behind each apparent miracle, however, stands the flawless performance of numerous highly complex systems. All are important. The failure of only one portion of a launch vehicle or spacecraft may cause failure of an entire mission. But the first to feel this awesome imperative for perfection are the propulsion systems, especially the engines. Unless they operate flawlessly first, none of the other systems will get a chance to perform in space. Perfection begins in the design of space hardware. This book emphasizes quality and reliability in the design of propulsion and engine systems. It draws deeply from the vast know-how and experience which have been the essence of several well-designed, reliable systems of the past and present. And, with a thoroughness and completeness not previously available, it tells how the present high state of reliability, gained through years of research and testing, can be maintained, and perhaps improved, in engines of the future. As man ventures deeper into space to explore the planets, the search for perfection in the design of propulsion systems will continue.” Some catastrophes with losses of life will be compared to show lapses in quality and safety and contrasted with a catastrophe without loss of life because of compliance with safety requirements. 1. October 24, 1960,(USSR) Nedelin Catastrophe, Death on the Steppes, 124 deaths 2. October 25, 1966,(USA) North American Rockwell, Apollo Block I Service Module Service(SM) Propulsion System fuel tank explosion/fire and destruction of SM and test cell, test engineer/conductor/author, Bill Manha,(the presenter) 0 injuries, 0 deaths 3. March 18, 1980,(USSR) Vostok 8A92M booster pad explosion, 48 deaths. 4. August 22, 2003,(Brazil) -Alcantara VLS -1, V03. Solid rocket ignited on pad, 21 deaths 5. Summer of 2006(USA) a payload organization inquired about requirements to fly a satellite with a new “safe” SpaceDev hybrid propulsion system using a solid polymer as the fuel and nitrous oxide as the oxidizer. The extensive titanium/nitrous oxide materials compatibility testing that was required discouraged the payload organization from further exploration of using the Shuttle as the launch vehicle. 6. July 26, 2007(USA) SpaceShipTwo nitrous oxide explosion, 3 seriously injured, 3 deaths The above listed catastrophic failures resulted in 210 deaths, but there were none on the Apollo SM explosion because of compliance with CalOSHA. This is an applied lesson learned of the Shuttle. Safety was not jeopardized without extensive materials compatibility testing. On the other hand, the nitrous oxide was erroneously identified as safe for launch from Shuttle or ISS which resulted in a catastrophic explosion and resulted in 3 major injuries, and 3 deaths. This is a testimony of a survivor of a catastrophic failure where safety rules were followed and the application of the lesson learned which confirmed safety and quality, as expressed by Von Braun, PERFECTION and SAFETY do MATTER!

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via a Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was taken to safety aboard the USS Hornet, where they were quartered in a mobile quarantine facility. Shown here is the Apollo 11 crew inside the quarantine facility as prayer is offered by Lt. Commander John Pirrto, USS Hornet Chaplain accompanied by U.S. President Richard Nixon (front right). With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

The Michoud Assembly Facility (MAF)

NASA Technical Reports Server (NTRS)

2000-01-01

NASA's Michoud Assembly Facility, located in eastern New Orleans, Louisiana, is an 832 acre site that is a government-owned, contractor-operated component of the George C. Marshall Space Flight Center (MSFC). The facility was acquired by NASA in 1961 at the recommendation of Dr. Wernher von Braun and his rocket team in Huntsville Alabama. The cavernous plant served as the assembly facility for the Saturn launch vehicles and most recently the external tank (ET) used for the Space Shuttle Program. The facility features one of the world's biggest manufacturing plants with 43 acres under one roof and a port with deep-water access for the transportation of large space structures. When completed, space hardware is towed on a barge across the Gulf of Mexico, around Florida and up to Kennedy Space Center. The original tract of land was part of a 34,500 acre French Royal land grant to local merchant, Gilbert Antoine de St. Maxent in 1763. Later, the land was acquired by French transplant Antoine Michoud, the son of Napoleon's Administrator of Domains, who moved to the city in 1827. Michoud operated a sugar cane plantation and refinery on the site until his death in 1863. His heirs continued operating the refinery and kept the original St. Maxent estate intact into the 20th century. Two brick smokestacks from the original refinery still stand before the Michoud facility today.

Around Marshall

NASA Image and Video Library

2000-09-09

NASA's Michoud Assembly Facility, located in eastern New Orleans, Louisiana, is an 832 acre site that is a government-owned, contractor-operated component of the George C. Marshall Space Flight Center (MSFC). The facility was acquired by NASA in 1961 at the recommendation of Dr. Wernher von Braun and his rocket team in Huntsville Alabama. The cavernous plant served as the assembly facility for the Saturn launch vehicles and most recently the external tank (ET) used for the Space Shuttle Program. The facility features one of the world's biggest manufacturing plants with 43 acres under one roof and a port with deep-water access for the transportation of large space structures. When completed, space hardware is towed on a barge across the Gulf of Mexico, around Florida and up to Kennedy Space Center. The original tract of land was part of a 34,500 acre French Royal land grant to local merchant, Gilbert Antoine de St. Maxent in 1763. Later, the land was acquired by French transplant Antoine Michoud, the son of Napoleon's Administrator of Domains, who moved to the city in 1827. Michoud operated a sugar cane plantation and refinery on the site until his death in 1863. His heirs continued operating the refinery and kept the original St. Maxent estate intact into the 20th century. Visible on the right, is one of two brick smokestacks from the original refinery that still stand before the Michoud facility today.

Werner Heisenberg (1901-1976)

NASA Astrophysics Data System (ADS)

Yang, Chen Ning

2013-05-01

Werner Heisenberg was one of the greatest physicists of all times. When he started out as a young research worker, the world of physics was in a very confused and frustrating state, which Abraham Pais has described1 as: It was the spring of hope, it was the winter of despair using Charles Dickens' words in A Tale of Two Cities. People were playing a guessing game: There were from time to time great triumphs in proposing, through sheer intuition, make-shift schemes that amazingly explained some regularities in spectral physics, leading to joy. But invariably such successes would be followed by further work which reveal the inconsistency or inadequacy of the new scheme, leading to despair...

Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome.

PubMed

Bagley, Mark C; Davis, Terence; Rokicki, Michal J; Widdowson, Caroline S; Kipling, David

2010-02-01

UR-13756 is a potent and selective p38 mitogen-activated protein kinase (MAPK) inhibitor, reported to have good bioavailability and pharmacokinetic properties and, thus, is of potential use in the treatment of accelerated aging in Werner syndrome. Irradiation of 2-chloroacrylonitrile and methylhydrazine in ethanol at 100 °C gives 1-methyl-3-aminopyrazole, which reacts with 4-fluorobenzaldehyde and a ketone, obtained by Claisen condensation of 4-picoline, in a Hantzsch-type 3-component hereocyclocondensation, to give the pyrazolopyridine UR-13756. UR-13756 shows p38 MAPK inhibitory activity in human telomerase reverse transcriptase-immortalized HCA2 dermal fibroblasts, with an IC(50) of 80 nm, as shown by ELISA, is 100% efficacious for up to 24 h at 1.0 μm and displays excellent kinase selectivity over the related stress-activated c-Jun kinases. In addition, UR-13756 is an effective p38 inhibitor at 1.0 μm in Werner syndrome cells, as shown by immunoblot. The convergent synthesis of UR-13756 is realized using microwave dielectric heating and provides a highly selective inhibitor that shows excellent selectivity for p38 MAPK over c-Jun N-terminal kinase.

POLD1 Germline Mutations in Patients Initially Diagnosed with Werner Syndrome

PubMed Central

Lessel, Davor; Hisama, Fuki M.; Szakszon, Katalin; Saha, Bidisha; Sanjuanelo, Alexander Barrios; Salbert, Bonnie A.; Steele, Pamela D.; Baldwin, Jennifer; Brown, W. Ted; Piussan, Charles; Plauchu, Henri; Szilvássy, Judit; Horkay, Edit; Hoögel, Josef; Martin, George M.; Herr, Alan J.; Oshima, Junko; Kubisch, Christian

2015-01-01

Segmental progeroid syndromes are rare, heterogeneous disorders characterized by signs of premature aging affecting more than one tissue or organ. A prototypic example is the Werner syndrome (WS), caused by biallelic germline mutations in the Werner helicase gene (WRN). While heterozygous lamin A/C (LMNA) mutations are found in a few nonclassical cases of WS, another 10%–15% of patients initially diagnosed with WS do not have mutations in WRN or LMNA. Germline POLD1 mutations were recently reported in five patients with another segmental progeroid disorder: mandibular hypoplasia, deafness, progeroid features syndrome. Here, we describe eight additional patients with heterozygous POLD1 mutations, thereby substantially expanding the characterization of this new example of segmental progeroid disorders. First, we identified POLD1 mutations in patients initially diagnosed with WS. Second, we describe POLD1 mutation carriers without clinically relevant hearing impairment or mandibular underdevelopment, both previously thought to represent obligate diagnostic features. These patients also exhibit a lower incidence of metabolic abnormalities and joint contractures. Third, we document postnatal short stature and premature greying/loss of hair in POLD1 mutation carriers. We conclude that POLD1 germline mutations can result in a variably expressed and probably underdiagnosed segmental progeroid syndrome. PMID:26172944

The odontological identification of Eva Braun Hitler.

PubMed

Keiser-Nielsen, S; Strøm, F

1983-01-01

On May 7th-9th, 1945, a team of Russian pathologists autopsied several bodies found in and near the Fuehrer Bunker in Berlin; among them, a female body (No. 13) was later identified as that of Eva Braun Hitler (EBH), mainly by means of a gold bridge from the lower right jaw. A postmortem photograph of this bridge also shows a separate gold filling. Data now available on the dental treatment of EBH have permitted the present authors to substantiate that this gold filling also came from the mouth of EBH. Further speculation about the fate of EBH would henceforth seem professionally unfounded.

Rovibrationally-Resolved Direct Photodissociation Through The Lyman And Werner Transitions Of H_{2}

NASA Astrophysics Data System (ADS)

Gay, Christopher; Stancil, P. C.

2008-03-01

Direct photodissociation cross sections have been obtained for the Lyman and Werner transitions of H2 using a combination of ab initio and experimentally derived potential curves and dipole transition moments. The partial cross sections have been evaluated for transitions from all 301 rovibrational levels (v'',J'') of the ground electronic state and over a wavelength range that extends from 10nm to the dissociation threshold for each particular rovibrational state. For UV-irradiated molecular gas with column densities of 1016-1019cm-2, direct photodissociation can compete with the Solomon process as an H2 destruction process. This research was supported by NASA grant NNG06GJ11G from the Astrophysics Theory Program.

Sudden birth versus sudden death of entanglement for the extended Werner-like state in a dissipative environment

NASA Astrophysics Data System (ADS)

Shan, Chuan-Jia; Chen, Tao; Liu, Ji-Bing; Cheng, Wei-Wen; Liu, Tang-Kun; Huang, Yan-Xia; Li, Hong

2010-06-01

In this paper, we investigate the dynamical behaviour of entanglement in terms of concurrence in a bipartite system subjected to an external magnetic field under the action of dissipative environments in the extended Werner-like initial state. The interesting phenomenon of entanglement sudden death as well as sudden birth appears during the evolution process. We analyse in detail the effect of the purity of the initial entangled state of two qubits via Heisenberg XY interaction on the apparition time of entanglement sudden death and entanglement sudden birth. Furthermore, the conditions on the conversion of entanglement sudden death and entanglement sudden birth can be generalized when the initial entangled state is not pure. In particular, a critical purity of the initial mixed entangled state exists, above which entanglement sudden birth vanishes while entanglement sudden death appears. It is also noticed that stable entanglement, which is independent of different initial states of the qubits (pure or mixed state), occurs even in the presence of decoherence. These results arising from the combination of the extended Werner-like initial state and dissipative environments suggest an approach to control and enhance the entanglement even after purity induced sudden birth, death and revival.

n/a

NASA Image and Video Library

1969-07-24

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). Here the quarantined Apollo 11 crew members (l to r) Armstrong, Collins, and Aldrin, and U.S. President Richard Milhous Nixon share laughs over a comment made by fellow astronaut Frank Borman, Apollo 8 commander. The president was aboard the recovery vessel awaiting return of the astronauts. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

U.S. President Richard Milhous Nixon (center), is saluted by the honor guard of flight deck crewmen when he arrives aboard the U.S.S. Hornet, prime recovery ship for the Apollo 11 mission, to watch recovery operations and welcome the astronauts home. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF) for 21 days following the mission. The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun.

Rudolf Hermann, wind tunnels and aerodynamics

NASA Astrophysics Data System (ADS)

Lundquist, Charles A.; Coleman, Anne M.

2008-04-01

Rudolf Hermann was born on December 15, 1904 in Leipzig, Germany. He studied at the University of Leipzig and at the Aachen Institute of Technology. His involvement with wind tunnels began in 1934 when Professor Carl Wieselsberger engaged him to work at Aachen on the development of a supersonic wind tunnel. On January 6, 1936, Dr. Wernher von Braun visited Dr. Hermann to arrange for use of the Aachen supersonic wind tunnel for Army problems. On April 1, 1937, Dr. Hermann became Director of the Supersonic Wind Tunnel at the Army installation at Peenemunde. Results from the Aachen and Peenemunde wind tunnels were crucial in achieving aerodynamic stability for the A-4 rocket, later designated as the V-2. Plans to build a Mach 10 'hypersonic' wind tunnel facility at Kochel were accelerated after the Allied air raid on Peenemunde on August 17, 1943. Dr. Hermann was director of the new facility. Ignoring destruction orders from Hitler as WWII approached an end in Europe, Dr. Hermann and his associates hid documents and preserved wind tunnel components that were acquired by the advancing American forces. Dr. Hermann became a consultant to the Air Force at its Wright Field in November 1945. In 1951, he was named professor of Aeronautical Engineering at the University of Minnesota. In 1962, Dr. Hermann became the first Director of the Research Institute at the University of Alabama in Huntsville (UAH), a position he held until he retired in 1970.

A double commutant theorem for Murray–von Neumann algebras

PubMed Central

Liu, Zhe

2012-01-01

Murray–von Neumann algebras are algebras of operators affiliated with finite von Neumann algebras. In this article, we study commutativity and affiliation of self-adjoint operators (possibly unbounded). We show that a maximal abelian self-adjoint subalgebra of the Murray–von Neumann algebra associated with a finite von Neumann algebra is the Murray–von Neumann algebra , where is a maximal abelian self-adjoint subalgebra of and, in addition, is . We also prove that the Murray–von Neumann algebra with the center of is the center of the Murray–von Neumann algebra . Von Neumann’s celebrated double commutant theorem characterizes von Neumann algebras as those for which , where , the commutant of , is the set of bounded operators on the Hilbert space that commute with all operators in . At the end of this article, we present a double commutant theorem for Murray–von Neumann algebras. PMID:22543165

Werner states and the two-spinors Heisenberg anti-ferromagnet

NASA Astrophysics Data System (ADS)

Batle, J.; Casas, M.; Plastino, A.; Plastino, A. R.

2005-08-01

We ascertain, following ideas of Arnesen, Bose, and Vedral concerning thermal entanglement [Phys. Rev. Lett. 87 (2001) 017901] and using the statistical tool called entropic non-triviality [P.W. Lamberti, M.T. Martin, A. Plastino, O.A. Rosso, Physica A 334 (2004) 119], that there is a one-to-one correspondence between (i) the mixing coefficient x of a Werner state, on the one hand, and (ii) the temperature T of the one-dimensional Heisenberg two-spin chain with a magnetic field B along the z-axis, on the other one. This is true for each value of B below a certain critical value B. The pertinent mapping depends on the particular B-value one selects within such a range.

Experimental detection of steerability in Bell local states with two measurement settings

NASA Astrophysics Data System (ADS)

Orieux, Adeline; Kaplan, Marc; Venuti, Vivien; Pramanik, Tanumoy; Zaquine, Isabelle; Diamanti, Eleni

2018-04-01

Steering, a quantum property stronger than entanglement but weaker than non-locality in the quantum correlation hierarchy, is a key resource for one-sided device-independent quantum key distribution applications, in which only one of the communicating parties is trusted. A fine-grained steering inequality was introduced in (2014 Phys. Rev. A 90 050305), enabling for the first time the detection of steering in all steerable two-qubit Werner states using only two measurement settings. Here, we numerically and experimentally investigate this inequality for generalized Werner states and successfully detect steerability in a wide range of two-photon polarization-entangled Bell local states generated by a parametric down-conversion source.

Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics).

PubMed

Ozdemir, Vural; Endrenyi, Laszlo; Aynacıoğlu, Sükrü; Bragazzi, Nicola Luigi; Dandara, Collet; Dove, Edward S; Ferguson, Lynnette R; Geraci, Christy Jo; Hafen, Ernst; Kesim, Belgin Eroğlu; Kolker, Eugene; Lee, Edmund J D; Llerena, Adrian; Nacak, Muradiye; Shimoda, Kazutaka; Someya, Toshiyuki; Srivastava, Sanjeeva; Tomlinson, Brian; Vayena, Effy; Warnich, Louise; Yaşar, Umit

2014-04-01

This article announces the recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine by the Pacific Rim Association for Clinical Pharmacogenetics (PRACP): Bernard Lerer, professor of psychiatry and director of the Biological Psychiatry Laboratory, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. The Werner Kalow Responsible Innovation Prize is given to an exceptional interdisciplinary scholar who has made highly innovative and enduring contributions to global omics science and personalized medicine, with both vertical and horizontal (transdisciplinary) impacts. The prize is established in memory of a beloved colleague, mentor, and friend, the late Professor Werner Kalow, who cultivated the idea and practice of pharmacogenetics in modern therapeutics commencing in the 1950s. PRACP, the prize's sponsor, is one of the longest standing learned societies in the Asia-Pacific region, and was founded by Kalow and colleagues more than two decades ago in the then-emerging field of pharmacogenetics. In announcing this inaugural prize and its winner, we seek to highlight the works of prize winner, Professor Lerer. Additionally, we contextualize the significance of the prize by recalling the life and works of Professor Kalow and providing a brief socio-technical history of the rise of pharmacogenetics and personalized medicine as a veritable form of 21(st) century scientific practice. The article also fills a void in previous social science analyses of pharmacogenetics, by bringing to the fore the works of Kalow from 1995 to 2008, when he presciently noted the rise of yet another field of postgenomics inquiry--pharmacoepigenetics--that railed against genetic determinism and underscored the temporal and spatial plasticity of genetic components of drug response, with invention of the repeated drug administration (RDA) method that estimates the dynamic heritabilities of drug response. The prize goes a long way to cultivate transgenerational capacity and broader cognizance of the concept and practice of responsible innovation as an important criterion of 21(st) century omics science and personalized medicine. A new call is presently in place for the 2016 PRACP Werner Kalow prize. Nominations can be made in support of an exceptional individual interdisciplinary scholar, or alternatively, an entire research team, from any region in the world with a record of highly innovative contributions to global omics science and/or personalized medicine, in the spirit of responsible innovation. The application process is straightforward, requiring a signed, 1500-word nomination letter (by the applicant or sponsor) submitted not later than May 31, 2015.

Around Marshall

NASA Image and Video Library

1963-09-09

NASA's Michoud Assembly Facility, located in eastern New Orleans, Louisiana, is an 832 acre site that is a government-owned, contractor-operated component of the George C. Marshall Space Flight Center (MSFC). The facility was acquired by NASA in 1961 at the recommendation of Dr. Wernher von Braun and his rocket team in Huntsville Alabama. The cavernous plant served as the assembly facility for the Saturn launch vehicles and most recently the external tank (ET) used for the Space Shuttle Program. The facility features one of the world's biggest manufacturing plants with 43 acres under one roof and a port with deep-water access for the transportation of large space structures. When completed, space hardware is towed on a barge across the Gulf of Mexico, around Florida and up to Kennedy Space Center. The original tract of land was part of a 34,500 acre French Royal land grant to local merchant, Gilbert Antoine de St. Maxent in 1763. Later, the land was acquired by French transplant Antoine Michoud, the son of Napoleon's Administrator of Domains, who moved to the city in 1827. Michoud operated a sugar cane plantation and refinery on the site until his death in 1863. His heirs continued operating the refinery and kept the original St. Maxent estate intact into the 20th century. Two brick smokestacks from the original refinery still stand before the Michoud facility today as seen in the lower half of this photograph taken in the 1960's, while the upper half reflects the area during the time of the sugar cane plantation workers.

Space Technology Industry Forum

NASA Image and Video Library

2010-07-13

Bobby Braun, far left, NASA Chief Technologist, speaks during the NASA New Space Technology Industry Forum being held at the University of Maryland in College Park on Wednesday, July 14, 2010. Mr. Braun is joined on the panel by James Reuther, Director of Strategic Integration at NASA Headquarters, second from left; Keith Belvin, NASA Systems Engineer at NASA Langley Research Center and Ramona Travis, NASA Stennis Space Center Chief Technologist, far right. During the two-day event, speakers are focusing on the president's fiscal year 2011 budget request for NASA's new Space Technology Program. Representatives from industry, academia and the federal government are in attendance to discuss strategy, development and implementation of NASA's proposed new technology-enabled exploration. Photo Credit: (NASA/Carla Cioffi)

A rare cause of acute abdominal pain: Herlyn-Werner-Wunderlich syndrome.

PubMed

Aydin, Ramazan; Ozdemir, Ayse Zehra; Ozturk, Bahadir; Bilgici, Meltem Ceyhan; Tosun, Migraci

2014-01-01

Herlyn-Werner-Wunderlich (HWW) syndrome is a rare müllerian duct anomaly with uterus didelphys, unilateral obstructed hemivagina, and ipsilateral renal agenesis. Patients with this syndrome generally present after menarche with pelvic pain and mass and, rarely, primary infertility in later years. Strong suspicion and knowledge of this syndrome are mandatory for an accurate diagnosis. A 14-year-old female patient presented with acute retention of urine and abdominopelvic pain. Her condition was diagnosed with the use ultrasonography and magnetic resonance imaging as a case of HWW syndrome. She was treated with vaginal hemiseptal resection. The HWW syndrome should be considered among the differential diagnoses in girls with renal anomalies presenting with pelvic mass, symptoms of acute abdominal pain, and acute urinary retention.

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

U.S. President Richard Milhous Nixon (center), aboard the U.S.S. Hornet aircraft carrier, used binoculars to watch the Apollo 11 Lunar Mission Recovery. Standing next to the President is astronaut Frank Borman, Apollo 8 Commander. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet where they were quartered in a Mobile Quarantine Facility (MQF) for 21 days post mission. The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

U.S. President Richard Milhous Nixon Watches Apollo 11 Recovery

NASA Technical Reports Server (NTRS)

1969-01-01

U.S. President Richard Milhous Nixon (center), aboard the U.S.S. Hornet aircraft carrier, used binoculars to watch the Apollo 11 Lunar Mission Recovery. Standing next to the President is astronaut Frank Borman, Apollo 8 Commander. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet where they were quartered in a Mobile Quarantine Facility (MQF) for 21 days post mission. The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Apollo 11 Astronauts In Prayer Within Quarantine Facility

NASA Technical Reports Server (NTRS)

1969-01-01

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via a Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was taken to safety aboard the USS Hornet, where they were quartered in a mobile quarantine facility. Shown here is the Apollo 11 crew inside the quarantine facility as prayer is offered by Lt. Commander John Pirrto, USS Hornet Chaplain accompanied by U.S. President Richard Nixon (front right). With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Writing My Way to My Future | Poster

Cancer.gov

By Nathalie Walker, Guest Writer Editor’s note: This article is the second in a series describing one student’s perspective on her experiences as a Werner H. Kirsten student intern. “The future depends on what you do today.” Those wise words were spoken by Mahatma Gandhi. Before I started my Werner H. Kirsten (WHK) student internship, I did not know what I know now. I only knew what each of Gandhi’s words meant individually. I now understand the full meaning of the phrase. To me, Gandhi’s words mean that nothing in life is handed to you. You have to work hard today to get the results you want tomorrow.

WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects.

PubMed

Yokote, Koutaro; Chanprasert, Sirisak; Lee, Lin; Eirich, Katharina; Takemoto, Minoru; Watanabe, Aki; Koizumi, Naoko; Lessel, Davor; Mori, Takayasu; Hisama, Fuki M; Ladd, Paula D; Angle, Brad; Baris, Hagit; Cefle, Kivanc; Palanduz, Sukru; Ozturk, Sukru; Chateau, Antoinette; Deguchi, Kentaro; Easwar, T K M; Federico, Antonio; Fox, Amy; Grebe, Theresa A; Hay, Beverly; Nampoothiri, Sheela; Seiter, Karen; Streeten, Elizabeth; Piña-Aguilar, Raul E; Poke, Gemma; Poot, Martin; Posmyk, Renata; Martin, George M; Kubisch, Christian; Schindler, Detlev; Oshima, Junko

2017-01-01

Werner syndrome (WS) is a rare autosomal recessive disorder characterized by a constellation of adult onset phenotypes consistent with an acceleration of intrinsic biological aging. It is caused by pathogenic variants in the WRN gene, which encodes a multifunctional nuclear protein with exonuclease and helicase activities. WRN protein is thought to be involved in optimization of various aspects of DNA metabolism, including DNA repair, recombination, replication, and transcription. In this update, we summarize a total of 83 different WRN mutations, including eight previously unpublished mutations identified by the International Registry of Werner Syndrome (Seattle, WA) and the Japanese Werner Consortium (Chiba, Japan), as well as 75 mutations already reported in the literature. The Seattle International Registry recruits patients from all over the world to investigate genetic causes of a wide variety of progeroid syndromes in order to contribute to the knowledge of basic mechanisms of human aging. Given the unusually high prevalence of WS patients and heterozygous carriers in Japan, the major goal of the Japanese Consortium is to develop effective therapies and to establish management guidelines for WS patients in Japan and elsewhere. This review will also discuss potential translational approaches to this disorder, including those currently under investigation. © 2016 WILEY PERIODICALS, INC.

Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype

PubMed Central

Kamath-Loeb, Ashwini S.; Zavala-van Rankin, Diego G.; Flores-Morales, Jeny; Emond, Mary J.; Sidorova, Julia M.; Carnevale, Alessandra; Cárdenas-Cortés, Maria del Carmen; Norwood, Thomas H.; Monnat, Raymond J.; Loeb, Lawrence A.; Mercado-Celis, Gabriela E.

2017-01-01

Loss-of-function mutations in the WRN helicase gene cause Werner syndrome- a progeroid syndrome with an elevated risk of cancer and other age-associated diseases. Large numbers of single nucleotide polymorphisms have been identified in WRN. We report here the organismal, cellular, and molecular phenotypes of variant rs3087425 (c. 2500C > T) that results in an arginine to cysteine substitution at residue 834 (R834C) and up to 90% reduction of WRN helicase activity. This variant is present at a high (5%) frequency in Mexico, where we identified 153 heterozygous and three homozygous individuals among 3,130 genotyped subjects. Family studies of probands identified ten additional TT homozygotes. Biochemical analysis of WRN protein purified from TT lymphoblast cell lines confirmed that the R834C substitution strongly and selectively reduces WRN helicase, but not exonuclease activity. Replication track analyses showed reduced replication fork progression in some homozygous cells following DNA replication stress. Among the thirteen TT homozygotes, we identified a previously unreported and statistically significant gender bias in favor of males (p = 0.0016), but none of the clinical findings associated with Werner syndrome. Our results indicate that WRN helicase activity alone is not rate-limiting for the development of clinical WS. PMID:28276523

The Spectrum of WRN Mutations in Werner Syndrome Patients

PubMed Central

Huang, Shurong; Lee, Lin; Hanson, Nancy B.; Lenaerts, Catherine; Hoehn, Holger; Poot, Martin; Rubin, Craig D.; Chen, Da-Fu; Yang, Chih-Chao; Juch, Heike; Dorn, Thomas; Spiegel, Roland; Oral, Elif Arioglu; Abid, Mohammed; Battisti, Carla; Lucci-Cordisco, Emanuela; Neri, Giovanni; Steed, Erin H.; Kidd, Alexa; Isley, William; Showalter, David; Vittone, Janet L.; Konstantinow, Alexander; Ring, Johannes; Meyer, Peter; Wenger, Sharon L.; von Herbay, Axel; Wollina, Uwe; Schuelke, Markus; Huizenga, Carin R.; Leistritz, Dru F.; Martin, George M.; Mian, I. Saira; Oshima, Junko

2007-01-01

The International Registry of Werner syndrome (www.wernersyndrome.org) has been providing molecular diagnosis of the Werner syndrome (WS) for the past decade. The present communication summarizes, from among 99 WS subjects, the spectrum of 50 distinct mutations discovered by our group and by others since the WRN gene (also called RECQL2 or REQ3) was first cloned in 1996; 25 of these have not previously been published. All WRN mutations reported thus far have resulted in the elimination of the nuclear localization signal at the C-terminus of the protein, precluding functional interactions in the nucleus; thus, all could be classified as null mutations. We now report two new mutations in the N-terminus that result in instability of the WRN protein. Clinical data confirm that the most penetrant phenotype is bilateral ocular cataracts. Other cardinal signs were seen in more than 95% of the cases. The median age of death, previously reported to be in the range of 46–48 years, is 54 years. Lymphoblastoid cell lines (LCLs) have been cryopreserved from the majority of our index cases, including material from nuclear pedigrees. These, as well as inducible and complemented hTERT (catalytic subunit of human telomerase) immortalized skin fibroblast cell lines are available to qualified investigators. Published 2006 Wiley-Liss, Inc.† PMID:16673358

Laparoscopic revision of Billroth II with Braun anastomosis into Roux-en-Y anatomy in a patient with intestinal malrotation.

PubMed

Garofalo, Fabio; Abouzahr, Omar; Atlas, Henri; Denis, Ronald; Garneau, Pierre; Huynh, Hai; Pescarus, Radu

2018-01-01

Various reconstructions of the gastro-intestinal tract have been described in the past after distal gastrectomy. Among these, a Billroth II (BII) anastomosis can be performed with the addition of the Omega entero-enterostomy that may theoretically reduce the alkaline reflux. Given the significant complications associated with this procedure such as biliary reflux, marginal ulceration, and afferent loop syndrome, a revision into a Roux-en-Y anatomy is generally recommended. A 73-year-old healthy male was referred to our foregut surgery service for treatment of severe biliary gastritis. The patient previously underwent an open distal gastrectomy with a BII reconstruction followed by a Braun-type entero-enterostomy 6 months later. His main complaint was worsening daily biliary reflux with constant regurgitations, which were non-responsive to medical treatment. The preoperative endoscopy confirmed the diagnosis of severe biliary gastritis secondary to alkaline reflux. The distance between the gastro-jejunostomy and the Braun anastomosis was also measured with a pediatric colonoscope and the length of the efferent limb was estimated to be 80 cm. Identification of the afferent and efferent limb was complicated by the patient's incomplete intestinal malrotation with the angle of Treitz being present in the right hypochondrium. Intra-operative gastroscopy enabled visualization of the jejuno-jejunostomy and ensured correct interpretation of the anatomy. Subsequently, resection of the afferent limb completed the revision into a Roux-en-Y anatomy. The patient recovered well after the surgery and was discharged home on post-operative day 2. At 6 months follow-up, the patient's reflux symptoms have completely disappeared. BII reconstruction with or without Braun entero-enterostomy is a classic historical option following distal gastrectomy. Surgical revision of a BII into a Roux-en-Y anatomy is a good solution for severe biliary reflux and other long-term complications. Intra-operative endoscopy is a great adjunct to laparoscopic exploration in case of complex surgical procedures.

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). Donned in biological isolation garments, the Apollo 11 crew members wave to well wishers as they leave the pick up helicopter making their way to the MQF. This portable facility served as their home until they reached the NASA Manned Spacecraft Center (MSC) Lunar Receiving Laboratory in Houston, Texas. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

PREFACE: EmerQuM 11: Emergent Quantum Mechanics 2011 (Heinz von Foerster Congress)

NASA Astrophysics Data System (ADS)

Grössing, Gerhard

2012-05-01

These proceedings comprise the plenary lectures and poster contributions of the 'Heinz von Foerster Conference 2011' on Emergent Quantum Mechanics (EmerQuM11), which was held at the University of Vienna, 11-13 November 2011. With the 5th International Heinz von Foerster Conference convened at the occasion of von Foerster's 100th birthday, the organizers opted for a twin conference to take place at the Large and Small Ceremonial Halls of the University's main building, respectively. The overall topic was chosen as 'Self-Organization and Emergence', a topic to which von Foerster was an early contributor. While the first conference ('Self-Organization and Emergence in Nature and Society') addressed a more general audience, the second one ('Emergent Quantum Mechanics') was intended as a specialist meeting with a contemporary topic that could both serve as an illustration of von Foerster's intellectual heritage and, more generally, point towards future directions in physics. We thus intended to bring together many of those physicists who are interested in or are working on attempts to understand quantum mechanics as emerging from a suitable classical (or, more generally, deeper level) physics. EmerQuM11 was organized by the Austrian Institute for Nonlinear Studies (AINS), with essential support from the Wiener Institute for Social Science Documentation and Methodology (WISDOM), the Department of Contemporary History at the University of Vienna, and the Heinz von Foerster-Gesellschaft. There were a number of individuals who contributed to the smooth course of our meeting and whom I would like to sincerely thank: Christian Bischof, Thomas Elze, Marianne Ertl, Gertrud Hafner, Werner Korn, Angelika Krawanja, Florian Krug and his team, Sonja Lang, Albert Müller, Ilse Müller, Irene Müller, Karl Müller, Armin Reautschnig, Marion Schirrmacher, Anton Staudinger, Roman Zlabinger, and, last but not least, my AINS colleagues Siegfried Fussy, Herbert Schwabl and Johannes Mesa Pascasio, the latter in particular for his invaluable technical help with these proceedings. Funds made available by the Federal Ministry of Science and Research (BMWF), the City of Vienna MA7 Science Funding, the Faculty of Historical and Cultural Studies, Blaha Office Furniture, and Padma AG Zurich are gratefully acknowledged. As for the nature of the search for a 'deeper level' foundation of quantum mechanics, a first difficulty already arises with respect to the question: Where do we start? One may look for quite different points of departure, such as an encompassing theory of quantum gravity. Or one may find arguments for the necessity to base one's approach at least on a relativistic formulation of the problem. Or one may discard searching for general principles for the time being, and develop an explicit physical model first. And so on. In fact, this is actually what is happening today in different research programs for emergent quantum mechanics, a fact which is also reflected in the rich variety of approaches presented at our meeting. This may be considered a very welcome situation, reminding us of Heinz von Foerster's dictum: 'Act always so as to increase the number of choices.' However, some may view this variety also as a drawback: There is not (yet?) a single, definite alternative theory that would challenge orthodox positions, for example, by providing different experimental predictions. However, the prevailing orthodoxy has shown throughout the 20th century to the present day, that a too restrictive attitude towards theoretical alternatives can lead to almost a standstill in coping with the serious shortcomings and contradictions of present-day physics. Many of us remember famous quantum physicists repeating in an almost mantra-like fashion that quantum theory, or experimental evidence, 'excludes hidden variables as a possibility', along with a reference to some or other newly found 'impossibility proof'. Yet we also recall John Bell's famous counter-statement: 'What is proved by impossibility proofs is lack of imagination.' In this sense, therefore, our task is to make use of the variety of the different approaches offered, for it is in scrutinizing each of them that a chance for further progress and understanding may emerge. The papers collected in these proceedings essentially follow the order of the plenary talks during the conference program, with the addition of the poster presentations. Prior to the contributions to EmerQuM11, the very first paper of these proceedings presents the opening lecture by Yves Couder who addressed both twin conferences with his talk on wave-particle duality in a classical system. (Although he was not able to participate personally, the contribution of Robert Carroll, a member of the academic advisory board, is included here. Regrettably, the lectures by John Bush, Marek Czachor, Mark Everitt, Felix Finster, and Lee Smolin could not be included, partly for copyright reasons.) Finally, I would like to thank Sarah Toms and Graham Douglas and their team at IOP Publishing (Bristol) for their friendly advice and help during the preparation of these proceedings. Vienna, April 2012 Gerhard Grössing

Mary A. Werner | NREL

Science.gov Websites

manage the portfolio of projects funded by non-DOE partners in the Deployment & Market Transformation Advanced and Renewable Technologies group. Education Executive MBA, University of Colorado, Denver B.S

Neutron interferometry: The pioneering contributions of Samuel A. Werner

NASA Astrophysics Data System (ADS)

Klein, A. G.

2006-11-01

In 1975, Sam Werner, while on the staff of the Scientific Laboratory of the Ford Motor Company, and his collaborators from Purdue University, Roberto Colella and Albert Overhauser, carried out one of the pioneering experiments in neutron interferometry at the 2 MW University of Michigan research reactor. It was the famous COW Experiment [Colella et al., Phys. Rev. Lett. 34 (1975) 1472] on gravitationally induced quantum interference. Shortly thereafter he moved to the University of Missouri in Columbia, to set up a program of neutron scattering research, including neutron interferometry. In the 25 years until his retirement a large number of beautiful experiments have been performed by Sam, with his group, his numerous students and many international collaborators. This work and its history are briefly reviewed in this paper.

PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma

ClinicalTrials.gov

2017-08-23

VHL Gene Mutation; VHL; VHL Syndrome; VHL Gene Inactivation; Von Hippel; Von Hippel-Lindau Disease; Von Hippel's Disease; Von Hippel-Lindau Syndrome, Modifiers of; Clear Cell Renal Cell Carcinoma; Clear Cell RCC; ccRCC

Angular distributions for the F+H2-->HF+H reaction: The role of the F spin-orbit excited state and comparison with molecular beam experiments

NASA Astrophysics Data System (ADS)

Tzeng, Yi-Ren; Alexander, Millard H.

2004-09-01

We report quantum mechanical calculations of center-of-mass differential cross sections (DCS) for the F+H2→HF+H reaction performed on the multistate [Alexander-Stark-Werner (ASW)] potential energy surfaces (PES) that describe the open-shell character of this reaction. For comparison, we repeat single-state calculations with the Stark-Werner (SW) and Hartke-Stark-Werner (HSW) PESs. The ASW DCSs differ from those predicted for the SW and HSW PES in the backward direction. These differences arise from nonadiabatic coupling between several electronic states. The DCSs are then used in forward simulations of the laboratory-frame angular distributions (ADs) measured by Lee, Neumark, and co-workers [J. Chem. Phys. 82, 3045 (1985)]. The simulations are scaled to match experiment over the range 12°<Θlab<80°. As a natural consequence of the reduced backward scattering, the ASW ADs are more forward and sideways scattered than predicted by the HSW PES. At the two higher collision energies (2.74 and 3.42 kcal/mol) the enhanced sideways scattering of HF v'=2 products bring the ASW ADs in very good agreement with the experiment. At the lowest collision energy (1.84 kcal/mol), the simulations, for all three sets of PESs consistently underestimate the sideways scattering. The residual disagreements, particularly at the lowest collision energy, may be due to the known deficiencies in the PESs.

Line overlap and self-shielding of molecular hydrogen in galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gnedin, Nickolay Y.; Draine, Bruce T., E-mail: gnedin@fnal.gov, E-mail: andrey@oddjob.uchicago.edu, E-mail: draine@astro.princeton.edu

2014-11-01

The effect of line overlap in the Lyman and Werner bands, often ignored in galactic studies of the atomic-to-molecular transition, greatly enhances molecular hydrogen self-shielding in low metallicity environments and dominates over dust shielding for metallicities below about 10% solar. We implement that effect in cosmological hydrodynamics simulations with an empirical model, calibrated against the observational data, and provide fitting formulae for the molecular hydrogen fraction as a function of gas density on various spatial scales and in environments with varied dust abundance and interstellar radiation field. We find that line overlap, while important for detailed radiative transfer in themore » Lyman and Werner bands, has only a minor effect on star formation on galactic scales, which, to a much larger degree, is regulated by stellar feedback.« less

Genetics Home Reference: Werner syndrome

MedlinePlus

... a role in natural ageing? Int J Biochem Cell Biol. 2005 May;37(5):947-60. Epub 2004 Dec 15. Review. Citation on ... are genome editing and CRISPR-Cas9? What is precision medicine? What is newborn ...

Von Hippel-Lindau Disease

MedlinePlus

What is Von Hippel-Lindau disease (VHL)? Von Hippel-Lindau disease (VHL) is a rare disease that causes tumors and cysts to grow in your body. They ... can become cancerous. What causes Von Hippel-Lindau disease (VHL)? Von Hippel-Lindau disease (VHL) is a ...

Pregnancy and delivery in women with von Willebrand's disease and different von Willebrand factor mutations.

PubMed

Castaman, Giancarlo; Tosetto, Alberto; Rodeghiero, Francesco

2010-06-01

Pregnancy in von Willebrand's disease may carry a significant risk of bleeding. Information on changes in factor VIII and von Willebrand factor and pregnancy outcome in relation to von Willebrand factor gene mutations are very scanty. We examined biological response to desmopressin, changes in factor VIII and von Willebrand factor and pregnancy outcome in a cohort of 23 women with von Willebrand's disease characterized at molecular level and prospectively followed during 2000-2007. Thirty-one pregnancies occurred during the study period. Remarkably, similar changes of factor VIII and von Willebrand factor were observed after desmopressin and during pregnancy in nine women with R854Q, R1374H, V1665E, V1822G and C2362F mutations. Women with von Willebrand's disease and R1205H and C1130F mutations (17 pregnancies in 12 women) had only a slight increase of factor VIII and von Willebrand factor during pregnancy while their response to desmopressin was marked but short-lived. For these women, two to three desmopressin administrations within the first 48 hours were sufficient to successfully manage vaginal delivery. Two women with recessive von Willebrand's disease due to compound heterozygosity for different gene mutations had a spontaneous, major increase in factor VIII while von Willebrand factor remained severely reduced. Desmopressin increased factor VIII and was clinically useful in the first case, while a factor VIII/von Willebrand factor concentrate was required in the second patient not responsive to the compound. Factor VIII/von Willebrand factor concentrate was also required for two women with type 2 A von Willebrand's disease with V1665E mutations who had no von Willebrand factor activity change during pregnancy. In one of them, delayed bleeding occurred 15 days later requiring treatment with Factor VIII/von Willebrand factor concentrate. No miscarriages or stillbirths occurred. Close follow-up and detailed guidelines for the management of parturition have produced a very low rate of immediate and late bleeding complications in this setting. Desmopressin was effective and safe in preventing significant bleeding at delivery in most of these patients.

Sufficient and necessary condition of separability for generalized Werner states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deng Dongling; Chen Jingling

2009-02-15

In a celebrated paper [Optics Communications 179, 447, 2000], A.O. Pittenger and M.H. Rubin presented for the first time a sufficient and necessary condition of separability for the generalized Werner states. Inspired by their ideas, we generalized their method to a more general case. We obtain a sufficient and necessary condition for the separability of a specific class of N d-dimensional system (qudits) states, namely special generalized Werner state (SGWS): W{sup [d{sup N}]}(v)=(1-v)(I{sup (N)})/(d{sup N}) +v|{psi}{sub d}{sup N}><{psi}{sub d}{sup N}|, where |{psi}{sub d}{sup N}>={sigma}{sub i=0}{sup d-1}{alpha}{sub i}|i...i> is an entangled pure state of N qudits system and {alpha}{sub i} satisfiesmore » two restrictions: (i) {sigma}{sub i=0}{sup d-1}{alpha}{sub i}{alpha}{sub i}*=1; (ii) Matrix 1/d (I{sup (1)}+T{sigma}{sub i{ne}}{sub j}{alpha}{sub i}|i>

A note on derivations of Murray-von Neumann algebras.

PubMed

Kadison, Richard V; Liu, Zhe

2014-02-11

A Murray-von Neumann algebra is the algebra of operators affiliated with a finite von Neumann algebra. In this article, we first present a brief introduction to the theory of derivations of operator algebras from both the physical and mathematical points of view. We then describe our recent work on derivations of Murray-von Neumann algebras. We show that the "extended derivations" of a Murray-von Neumann algebra, those that map the associated finite von Neumann algebra into itself, are inner. In particular, we prove that the only derivation that maps a Murray-von Neumann algebra associated with a factor of type II1 into that factor is 0. Those results are extensions of Singer's seminal result answering a question of Kaplansky, as applied to von Neumann algebras: The algebra may be noncommutative and may even contain unbounded elements.

Reduction of Werner Syndrome Protein Enhances G:C → A:T Transition by O6-Methylguanine in Human Cells.

PubMed

Suzuki, Tetsuya; Kuramoto, Yoshie; Kamiya, Hiroyuki

2018-05-21

O 6 -Methylguanine ( O 6 -MeG) is a damaged base produced by methylating reagents. The Werner syndrome protein (WRN) is a cancer-related human DNA helicase. The effects of WRN reduction on O 6 -MeG-caused mutagenesis were assessed by an siRNA-mediated knockdown in human U2OS cells, using a shuttle plasmid with a single O 6 -MeG base in the supF gene. The plasmid DNA was replicated in the cells, isolated, and electroporated into an Escherichia coli indicator strain. The lowered amount of WRN increased the frequency of mutations induced by O 6 -MeG, mainly G:C → A:T substitution. The increased mutation rate suggested that the cancer-related WRN suppresses the G:C → A:T substitution by O 6 -MeG in human cells.

Reply [to: Atlantic Tropical Cyclogenetic Processes during SOP-3 NAMMA in the GEOS-5 Global Data Assimilation and Forecast System

NASA Technical Reports Server (NTRS)

Reale, Oreste; Lau, William K.

2010-01-01

This article is a Reply to a Comment by Scott Braun on a previously published article by O. Reale, K.-M. Lau, and E. Brin: "Atlantic tropical cyclogenetic processes during SOP-3 NAMMA in the GEOS-5 global data assimilation and forecast system", by Reale, Lau and Brin, hereafter referred to as RA09. RA09 investigated the role of the Saharan Air Layer (SAL) in tropical cyclogenetic processes associated with a non-developing easterly wave observed during the Special Observation Period (SOP-3) phase of the 2006 NASA African Monsoon Multidisciplinary Analyses (MAMMA). The wave was chosen because both interact heavily with Saharan air. Results showed: a) very steep moisture gradients are associated with the SAL in forecasts and analyses even at great distance from the Sahara; b) a thermal dipole (warm above, cool below) in the non-developing case. RA09A suggested that radiative effect of dust may play some role in producing a thermal structure less favorable to cyclogenesis, and also indicated that only global horizontal resolutions on the order of 20-30 kilometers can capture the large-scale transport and the fine thermal structure of the SAL Braun (2010) questions those results attributing the wave dissipation to midlatitude air. The core discussion is on a dry filament preceding the wave, on the presence of dust, and on the origin of the air contained in this dry filament. In the 'Reply', higher resolution analyses than the ones used by Braun, taken at almost coincident times with Aqua and Terra passes, are shown, to emphasize how the channel of dry air associated with W1 is indeed rich in dust. Backtrajectories on a higher resolution grid are also performed, leading to results drastically different from Braun (2010), and in particularly showing that there is a clear contribution of Saharan air. Finally, the 'Reply' presents evidence on that analyses at a horizontal resolution of one degree are inadequate to investigate such feature.

75 FR 68773 - Meeting of the Ocean Research and Resources Advisory Panel

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-09

... Consortium for Ocean Leadership, 1201 New York Avenue, NW., 4th Floor, Washington, DC 20005. FOR FURTHER... science and management communities. Dated: November 2, 2010. D.J. Werner, Lieutenant Commander, Office of...

[Werner Catel--a protagonist in Nazi "pediatric euthanasia" and his post-war career].

PubMed

Petersen, Hans-Christian; Zankel, Sönke

2003-01-01

This article deals with the biography of Werner Catel, a German paediatrician and protagonist of the Nazi programme for "euthanasia of children". Based on original research into recently discovered source materials, two aspects of Catel's life are considered. Firstly, Catel's attitude towards "euthanasia" is analysed. This analysis is not limited to the period of National Socialism, but focuses also on the phase before 1933 and especially on the era after 1945. Secondly, the authors explore Catel's academic career. What effects on his career in the later Federal Republic of Germany had his exposed role in the Nazi programme for "euthanasia of children"? In this context it is also examined how the Christian-Albrechts-University of Kiel/Germany, which employed Catel until 1960 in a leading position, judged the work of its former professor after his death.

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard the craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). Donned in biological isolation garments, the Apollo 11 crew members (front to rear) Armstrong, Collins, and Aldrin leave the pick up helicopter making their way to the MQF. This portable facility served as their home until they reached the NASA Manned Spacecraft Center Lunar Receiving Laboratory in Houston, Texas. With the success of Apollo 11 mission the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Saturn Apollo Program

NASA Image and Video Library

1960-01-01

This photograph shows the Saturn-I first stage (S-1 stage) being transported to the test stand for a static test firing at the Marshall Space Flight Center. Soon after NASA began operations in October 1958, it was evident that sending people and substantial equipment beyond the Earth's gravitational field would require launch vehicles with weight-lifting capabilities far beyond any developed to that time. In early 1959, NASA accepted the proposal of Dr. Wernher von Braun for a multistage rocket, with a number of engines clustered in one or more of the stages to provide a large total thrust. The initiation of the Saturn launch vehicle program ultimately led to the study and preliminary plarning of many different configurations and resulted in production of three Saturn launch vehicles, the Saturn-I, Saturn I-B, and Saturn V. The Saturn family of launch vehicles began with the Saturn-I, a two-stage vehicle originally designated C-1. The research and development program was planned in two phases, or blocks: one for first stage development (Block I) and the second for both first and second stage development (Block-II). Saturn I had a low-earth-orbit payload capability of approximately 25,000 pounds. The design of the first stage (S-1 stage) used a cluster of propellant tanks containing liquid oxygen (LOX) and kerosene (RP-1), and eight H-1 engines, yielding a total thrust of 1,500,000 pounds. Of the ten Saturn-Is planned, the first eight were designed and built at the Marshall Space Flight Center, and the remaining two were built by the Chrysler Corporation.

Quarantined Apollo 11 Astronauts Addressed by U.S. President Nixon

NASA Technical Reports Server (NTRS)

1969-01-01

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted by helicopter and taken to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). Shown here are the Apollo 11 crew members (L to R) Neil Armstrong, Michael Collins, and Edwin Aldrin inside the MQF as U.S. President Richard Milhous Nixon speaks to them via intercom. The president was aboard the recovery vessel awaiting return of the astronauts. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Teófilo Tabanera, Father of the Argentine Space Program

NASA Astrophysics Data System (ADS)

de León, Pablo; Tabanera, Marcela; Tabanera, Marisol

2017-08-01

No other figure was able to organize and catalyze the seminal interest of space exploration in Argentina more than Teófilo Tabanera. Born in 1909, Tabanera showed an early interest in the possibilities of space travel and dedicated most of his life to popularize it in his country. He created the Sociedad Argentina Interplanetaria (1949), which was the first space enthusiast's organization in Latin America. Present in the first meeting of representatives of various space societies, which led to the creation of the International Astronautical Federation, Tabanera was able to bring his enthusiasm to this new organization. A prolific writer, Tabanera wrote the first books about space exploration in Spanish, and organized many courses and conferences on the subject. When the Comisión Nacional de Investigaciones Espaciales (the Argentine Space Agency) was created in 1960 by a decree of President Arturo Frondizi, Tabanera was appointed as its first administrator. There, with meager funds, he organized launch campaigns and international projects on sounding rockets. Thanks to his knowledge of the international space sector, Tabanera invited many experts to Argentina, among them Wernher von Braun and even the Apollo XI crew, just a few months after their return from the Moon. He continued his activities in the IAF (International Astronautical Federation) serving as vice president for seven terms, and was a cofounder of the International Academy of Astronautics (I.A.A.). His many contributions, both to the Argentine and international space sector, are a testimony to his undying enthusiasm and interest in space as a way of advancing humankind.

Diagnosis and management of von Willebrand's syndrome.

PubMed

Rick, M E

1994-05-01

von Willebrand's disease is the most common of the inherited bleeding disorders. It is caused by quantitative and/or qualitative abnormalities of von Willebrand factor, and it usually presents with bleeding from mucosal surfaces. The diagnosis is confirmed by measuring von Willebrand factor activity and antigen levels, factor VIII activity, and performing a multimer analysis of von Willebrand factor. Treatment may require plasma-derived concentrates, but can often be accomplished with DDAVP, a vasopressin analogue that causes transient release of von Willebrand factor from body storage sites.

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

Donned in biological isolation garments, the Apollo 11 crew members, (L-R) Edwin Aldrin, Neil Armstrong (waving), and Michael Collins exit the recovery pick up helicopter to board the U.S.S. Hornet aircraft carrier after splashdown. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). This portable facility served as their home until they reached the NASA Manned Spacecraft Center (MSC) Lunar Receiving Laboratory in Houston, Texas. The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center (KSC), Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Werher von Braun.

U.S. President Richard Milhous Nixon Arrives Aboard U.S.S. Hornet for Apollo 11 Recovery

NASA Technical Reports Server (NTRS)

1969-01-01

U.S. President Richard Milhous Nixon (center), is saluted by the honor guard of flight deck crewmen when he arrives aboard the U.S.S. Hornet, prime recovery ship for the Apollo 11 mission, to watch recovery operations and welcome the astronauts home. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF) for 21 days following the mission. The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun.

Apollo 11 Astronauts Share Laughs With U.S. President Nixon

NASA Technical Reports Server (NTRS)

1969-01-01

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). Here the quarantined Apollo 11 crew members (l to r) Armstrong, Collins, and Aldrin, and U.S. President Richard Milhous Nixon share laughs over a comment made by fellow astronaut Frank Borman, Apollo 8 commander. The president was aboard the recovery vessel awaiting return of the astronauts. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Historical Photograph of the Michoud Assembly Facility (MAF)

NASA Technical Reports Server (NTRS)

1963-01-01

NASA's Michoud Assembly Facility, located in eastern New Orleans, Louisiana, is an 832 acre site that is a government-owned, contractor-operated component of the George C. Marshall Space Flight Center (MSFC). The facility was acquired by NASA in 1961 at the recommendation of Dr. Wernher von Braun and his rocket team in Huntsville Alabama. The cavernous plant served as the assembly facility for the Saturn launch vehicles and most recently the external tank (ET) used for the Space Shuttle Program. The facility features one of the world's biggest manufacturing plants with 43 acres under one roof and a port with deep-water access for the transportation of large space structures. When completed, space hardware is towed on a barge across the Gulf of Mexico, around Florida and up to Kennedy Space Center. The original tract of land was part of a 34,500 acre French Royal land grant to local merchant, Gilbert Antoine de St. Maxent in 1763. Later, the land was acquired by French transplant Antoine Michoud, the son of Napoleon's Administrator of Domains, who moved to the city in 1827. Michoud operated a sugar cane plantation and refinery on the site until his death in 1863. His heirs continued operating the refinery and kept the original St. Maxent estate intact into the 20th century. Two brick smokestacks from the original refinery still stand before the Michoud facility today as seen in the lower half of this photograph taken in the 1960's, while the upper half reflects the area during the time of the sugar cane plantation workers.

Student Interns Tour Two NIH Facilities | Poster

Cancer.gov

Thirty-five Werner H. Kirsten student interns toured the National Library of Medicine and the National Institutes of Health Clinical Center in Bethesda in August to learn about the services and opportunities available.

Recollections of Physics and of Physicists During the 1920's

ERIC Educational Resources Information Center

Dennison, David M.

1974-01-01

Presents the author's recollections of the emergence of the new quantum theory and his associations with such men as Oskar Klein, Niels Bohr, Frederick Hund, Werner Heisenberg, J. J. Thomson, and others. (GS)

Werner Brandt legacy to PIXE: Past and present perspectives

NASA Astrophysics Data System (ADS)

Lapicki, Gregory

2014-01-01

Inner-shell ionization cross sections used in Particle-Induced X-ray Elemental (PIXE) analyses are routinely calculated in the ECPSSR [W. Brandt, G. Lapicki, Phys. Rev. A 23 (1981) 1717-1729] theory and/or semiempirical formulas scaled to that theory. Thirty years after the passing of Werner Brandt, with recognition of his seminal contributions to other research on positron physics and stopping power problems, the work and articles that progressed into the ECPSSR theory for inner-shell ionization by protons and heavier ions are recalled as Brandt's past legacy to the PIXE community. Applications of the ECPSSR and its evolution into the ECUSAR [G. Lapicki, Nucl. Instr. Meth. B 189 (2002) 8-20] theory over the last three decades are reviewed with perspectives on Brandt's present legacy.

NASA Chief Technologist Hosts Town Hall

NASA Image and Video Library

2010-05-24

Bobby Braun, NASA's Chief Technologist, answers questions during a Town Hall meeting to discuss agency-wide technology policy and programs at NASA Headquarters on Tuesday, May 25, 2010, in Washington. Photo Credit: (NASA/Carla Cioffi)

Saturn Apollo Program

NASA Image and Video Library

1969-07-24

The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was airlifted by helicopter and taken to safety aboard the U.S.S. Hornet, where they were quartered in a Mobile Quarantine Facility (MQF). Shown here are the Apollo 11 crew members (L to R) Neil Armstrong, Michael Collins, and Edwin Aldrin inside the MQF as U.S. President Richard Milhous Nixon speaks to them via intercom. The president was aboard the recovery vessel awaiting return of the astronauts. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

Inside NanoSail-D: A Tiny Satellite with Big Ideas

NASA Technical Reports Server (NTRS)

Alhorn, Dean C.; Agasid, Elwood; Casas, Joseph; Adams, Charles; O'Brien, Sue; Laue, Greg; Kitts, Chris

2011-01-01

"Small But Mighty" certainly describes the NanoSail-D experiment and mission. Its unique goals and designs were simple, but the implications of this technology are far reaching. From a tiny 3U CubeSat, NanoSail-D deployed a 10 square meter solar sail. This was the first sail vehicle to orbit the earth and was only the second time a sail was unfurled in space. The NanoSail-D team included: two NASA centers, Marshall and Ames, the universities of Alabama in Huntsville and Santa Clara in California, the Air Force Research Laboratory and many contractors including NeXolve, Gray Research and several others. The collaborative nature was imperative to the success of this project. In addition, the Army Space and Missile Defense Command, the Von Braun Center for Science and Innovation and Dynetics Inc. jointly sponsored the NanoSail-D project. This paper presents in-depth insight into the NanoSail-D development. Its design was a combination of left over space hardware coupled with cutting edge technology. Since this NanoSail-D mission was different from the first, several modifications were necessary for the second NanoSail-D unit. Unforeseen problems arose during refurbishment of the second unit and the team had to overcome these obstacles. Simple interfaces, clear responsibilities and division of effort allowed the team members to work independently on the common goal. This endeavor formed working relationships lasting well beyond the end of this mission. NanoSail-D pushed the technology envelop with future applications for all classes of satellites. NanoSail-D is truly a small but mighty satellite, which may cast a very big shadow for years to come.

Biochemical characterization of an exonuclease from Arabidopsis thaliana reveals similarities to the DNA exonuclease of the human Werner syndrome protein.

PubMed

Plchova, Helena; Hartung, Frank; Puchta, Holger

2003-11-07

The human Werner syndrome protein (hWRN-p) possessing DNA helicase and exonuclease activities is essential for genome stability. Plants have no homologue of this bifunctional protein, but surprisingly the Arabidopsis genome contains a small open reading frame (ORF) (AtWRNexo) with homology to the exonuclease domain of hWRN-p. Expression of this ORF in Escherichia coli revealed an exonuclease activity for AtWRN-exo-p with similarities but also some significant differences to hWRN-p. The protein digests recessed strands of DNA duplexes in the 3' --> 5' direction but hardly single-stranded DNA or blunt-ended duplexes. In contrast to the Werner exonuclease, AtWRNexo-p is also able to digest 3'-protruding strands. DNA with recessed 3'-PO4 and 3'-OH termini is degraded to a similar extent. AtWRNexo-p hydrolyzes the 3'-recessed strand termini of duplexes containing mismatched bases. AtWRNexo-p needs the divalent cation Mg2+ for activity, which can be replaced by Mn2+. Apurinic sites, cholesterol adducts, and oxidative DNA damage (such as 8-oxoadenine and 8-oxoguanine) inhibit or block the enzyme. Other DNA modifications, including uracil, hypoxanthine and ethenoadenine, did not inhibit AtWRNexo-p. A mutation of a conserved residue within the exonuclease domain (E135A) completely abolished the exonucleolytic activity. Our results indicate that a type of WRN-like exonuclease activity seems to be a common feature of the DNA metabolism of animals and plants.

NASA Chief Technologist Hosts Town Hall

NASA Image and Video Library

2010-05-24

Bobby Braun, right, NASA's Chief Technologist, answers questions during a Town Hall meeting to discuss agency-wide technology policy and programs at NASA Headquarters on Tuesday, May 25, 2010, in Washington. Photo Credit: (NASA/Carla Cioffi)

A note on derivations of Murray–von Neumann algebras

PubMed Central

Kadison, Richard V.; Liu, Zhe

2014-01-01

A Murray–von Neumann algebra is the algebra of operators affiliated with a finite von Neumann algebra. In this article, we first present a brief introduction to the theory of derivations of operator algebras from both the physical and mathematical points of view. We then describe our recent work on derivations of Murray–von Neumann algebras. We show that the “extended derivations” of a Murray–von Neumann algebra, those that map the associated finite von Neumann algebra into itself, are inner. In particular, we prove that the only derivation that maps a Murray–von Neumann algebra associated with a factor of type II1 into that factor is 0. Those results are extensions of Singer’s seminal result answering a question of Kaplansky, as applied to von Neumann algebras: The algebra may be noncommutative and may even contain unbounded elements. PMID:24469831

WHK Student Interns Named Top Scholars in Regeneron Science Talent Search | Poster

Cancer.gov

Two Werner H. Kirsten Student Interns were recently named Top Scholars in the 2017 Regeneron Science Talent Search, the nation’s most prestigious science and math competition for high school students.

Verbesserung der Symmetrie von Hirnaufnahmen entlang der Sagittalebene

NASA Astrophysics Data System (ADS)

Ens, Konstantin; Wenzel, Fabian; Fischer, Bernd

Die lokale Symmetrie von Hirnscans entlang der Sagittalebene zu ermitteln und zu modizifieren, ist für eine Reihe neurologischer Anwendungen interessant. Beispielsweise kann der voxelweise Vergleich von rechter und linker Hirnhälfte nur dann Aufschluss über die Lokalisierung von Läsionen geben, wenn durch Transformation ein Hirnscan eine möglichst hohe Symmetrie aufweist. Ein weiteres Anwendungsgebiet ist die Visualisierung von medialen Hirnschnitten, für die die Trennfläche beider Hirnhälfte möglichst eben sein sollte. Diese Arbeit stellt die Entwicklung eines Verfahrens vor, mit dessen Hilfe die Symmetrie von Hirnaufnahmen entlang der Sagittalebene verbessert werden kann. Dies geschieht unter Verwendung von aktiven Konturen, die mit Hilfe einer neuartigen Kostenfunktion gesteuert werden. Experimente am Ende der Arbeit mit strukturellen Kernspinaufnahmen demonstrieren die Leistungsfähigkeit des Verfahrens.

Delayed diagnosis of Herlyn-Werner-Wunderlich syndrome due to microperforation and pyocolpos in obstructed vaginal canal.

PubMed

Wozniakowska, Ewa; Torres, Anna; Milart, Pawel; Wozniak, Slawomir; Czuczwar, Piotr; Szkodziak, Piotr; Paszkowski, Tomasz

2014-08-01

To present a rare anomaly consisting of uterus didelphys, longitudinal vaginal septum, obstructed hemivagina with pyocolpos, fistula to the open vaginal canal, and ipsilateral renal agenesis, referred as Herlyn-Werner-Wunderlich syndrome (HWWS). A 14-year-old girl with recurring purulent vaginal discharge lasting for a few months. Preoperative examination revealed one vaginal canal with one cervical opening on the right side. There was a fistula leading from the obstructed vaginal canal to the left vagina. Intravaginal ultrasound examination demonstrated a longitudinal vaginal septum and a closed pyocolpos on the right side. The longitudinal vaginal septum was excised by way of electrocauterization under direct vision. HWWS should be considered in the differential diagnosis in patients with uterus didelphys and unusual symptoms such as pyocolpos and vaginal discharge. Copyright © 2014 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Microwave-Assisted Synthesis of a MK2 Inhibitor by Suzuki-Miyaura Coupling for Study in Werner Syndrome Cells

PubMed Central

Bagley, Mark C.; Baashen, Mohammed; Chuckowree, Irina; Dwyer, Jessica E.; Kipling, David; Davis, Terence

2015-01-01

Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2) inhibitors to study accelerated aging in Werner syndrome (WS) cells, including the cross-coupling of a 2-chloroquinoline with a 3-pyridinylboronic acid, the coupling of an aryl bromide with an indolylboronic acid and the reaction of a 3-amino-4-bromopyrazole with 4-carbamoylphenylboronic acid. In all of these processes, the Suzuki-Miyaura reaction was fast and relatively efficient using a palladium catalyst under microwave irradiation. The process was incorporated into a rapid 3-step microwave-assisted method for the synthesis of a MK2 inhibitor involving 3-aminopyrazole formation, pyrazole C-4 bromination using N-bromosuccinimide (NBS), and Suzuki-Miyaura cross-coupling of the pyrazolyl bromide with 4-carbamoylphenylboronic acid to give the target 4-arylpyrazole in 35% overall yield, suitable for study in WS cells. PMID:26046488

Observability, Anschaulichkeit and Abstraction: A Journey into Werner Heisenberg's Science and Philosophy

NASA Astrophysics Data System (ADS)

Lacki, Jan

2003-09-01

Werner Heisenberg was one of the greatest physicists of the 20th century. He participated as a front rank actor in the shaping of a good part of XXth century physics and directly witnessed most of the intellectual struggles which led to what he called “Wandlungen in den Grundlagen der exakten Naturwissenschaft”. This expression is borrowed from one of the many talks and writings he devoted to the analysis of the scientific and philosophical implications of his, and his fellows physicists, findings. Indeed, Heisenberg's scientific activity increasingly reflected his more general intellectual views. This makes him another magnificent representative of a glorious linage going from the remote times of modern science to Einstein, Bohr and the like. This “philosophical” vein started early in his scientific life, and got stronger with time, prompted by the highly demanding scientific, but also social and political context of his mature years.

Hyper telomere recombination accelerates replicative senescence and may promote premature aging

PubMed Central

Hagelstrom, R. Tanner; Blagoev, Krastan B.; Niedernhofer, Laura J.; Goodwin, Edwin H.; Bailey, Susan M.

2010-01-01

Werner syndrome and Bloom syndrome result from defects in the RecQ helicases Werner (WRN) and Bloom (BLM), respectively, and display premature aging phenotypes. Similarly, XFE progeroid syndrome results from defects in the ERCC1-XPF DNA repair endonuclease. To gain insight into the origin of cellular senescence and human aging, we analyzed the dependence of sister chromatid exchange (SCE) frequencies on location [i.e., genomic (G-SCE) vs. telomeric (T-SCE) DNA] in primary human fibroblasts deficient in WRN, BLM, or ERCC1-XPF. Consistent with our other studies, we found evidence of elevated T-SCE in telomerase-negative but not telomerase-positive backgrounds. In telomerase-negative WRN-deficient cells, T-SCE—but not G-SCE—frequencies were significantly increased compared with controls. In contrast, SCE frequencies were significantly elevated in BLM-deficient cells irrespective of genome location. In ERCC1-XPF-deficient cells, neither T- nor G-SCE frequencies differed from controls. A theoretical model was developed that allowed an in silico investigation into the cellular consequences of increased T-SCE frequency. The model predicts that in cells with increased T-SCE, the onset of replicative senescence is dramatically accelerated even though the average rate of telomere loss has not changed. Premature cellular senescence may act as a powerful tumor-suppressor mechanism in telomerase-deficient cells with mutations that cause T-SCE levels to rise. Furthermore, T-SCE-driven premature cellular senescence may be a factor contributing to accelerated aging in Werner and Bloom syndromes, but not XFE progeroid syndrome. PMID:20798040

Robust Exploration and Commercial Missions to the Moon Using NTR LANTR Propulsion and Lunar-Derived Propellants

NASA Technical Reports Server (NTRS)

Borowski, Stanley K.; Ryan, Stephen W.; Burke, Laura M.; McCurdy, David R.; Fittje, James E.; Joyner, Claude R.

2017-01-01

The nuclear thermal rocket (NTR) has frequently been identified as a key space asset required for the human exploration of Mars. This proven technology can also provide the affordable access through cislunar space necessary for commercial development and sustained human presence on the Moon. In his post-Apollo Integrated Space Program Plan (1970-1990), Wernher von Braun, proposed a reusable nuclear thermal propulsion stage (NTPS) to deliver cargo and crew to the Moon to establish a lunar base before undertaking human missions to Mars. The NTR option was selected by von Braun because it was a demonstrated technology capable of generating both high thrust and high specific impulse (Isp 900 s) twice that of todays best chemical rockets. In NASAs Mars Design Reference Architecture (DRA) 5.0 study, the crewed Mars transfer vehicle used three 25 klbf Pewee engines the smallest and highest performing engine tested in the Rover program along with graphite composite fuel. Smaller, lunar transfer vehicles consisting of a NTPS using three approximately 16.5 klbf Small Nuclear Rocket Engines (SNREs), an in-line propellant tank, plus the payload can enable a variety of reusable lunar missions. These include cargo delivery and crewed lunar landing missions. Even weeklong tourism missions carrying passengers into lunar orbit for a day of sightseeing and picture taking are possible. The NTR can play an important role in the next phase of lunar exploration and development by providing an affordable in-space lunar transportation system (LTS) that can allow initial outposts to evolve into settlements supported by a variety of commercial activities such as in-situ propellant production used to supply strategically located propellant depots and transportation nodes. The utilization of iron-rich volcanic glass or lunar polar ice (LPI) deposits (each estimated at billions of metric tons) for propellant production can significantly reduce the launch mass requirements from Earth and can enable reusable, surface-based lunar landing vehicles (LLVs) using liquid oxygen/hydrogen (LOX/LH2) chemical rocket engines. Afterwards, LOX/LH2 propellant depots can be established in lunar equatorial and polar orbits to supply the LTS. At this point a modified version of the conventional NTR called the LOX-augmented NTR, or LANTR would be introduced into the LTS allowing bipropellant operation and leveraging the mission benefits of refueling with lunar-derived propellants for Earth return. The bipropellant LANTR engine utilizes the large divergent section of its nozzle as an afterburner into which oxygen is injected and supersonically combusted with nuclear preheated hydrogen emerging from the engines choked sonic throat essentially scramjet propulsion in reverse. By varying the oxygen-to-hydrogen mixture ratio, LANTR engines can operate over a range of thrust and Isp values while the reactor core power level remains relatively constant. Eventually, a LANTR-based LTS can enable a rapid commuter shuttle with one-way trip times to and from the Moon ranging from 36 to 24 hours. Even if only 1 of the extracted propellant from identified volcanic glass and polar ice deposits were available for use in lunar orbit, such a supply could support daily commuter flights to the Moon for many thousands of years! An evolutionary mission architecture is outlined and a variety of lunar missions and transfer vehicle designs are examined, along with the increasing demands on propellant production as mission complexity increases. A comparison of vehicle features and engine operating characteristics, for both NTR and LANTR engines, is also provided along with a brief discussion on the propellant production issues associated with using volcanic glass and LPI as source material.

Back to the future: the role of the ISS and future space stations in planetary exploration.

NASA Astrophysics Data System (ADS)

Muller, Christian; Moreau, Didier

2010-05-01

Space stations as stepping stones to planets appear already in the1954 Disney-von Braun anticipation TV show but the first study with a specific planetary scientific objective was the ANTEUS project of 1978. This station was an evolution of SPACELAB hardware and was designed to analyse Mars samples with better equipment than the laboratory of the VIKING landers. It would have played the role of the reception facility present in the current studies of Mars sample return, after analysis, the "safe" samples would have been returned to earth by the space shuttle. This study was followed by the flights of SPACELAB and MIR. Finally after 35 years of development, the International Space Station reaches its final configuration in 2010. Recent developments of the international agreement between the space agencies indicate a life extending to 2025, it is already part of the exploration programme as its crews prepare the long cruise flights and missions to the exploration targets. It is now time to envisage also the use of this stable 350 tons spacecraft for planetary and space sciences. Planetary telescopes are an obvious application; the present SOLAR payload on COLUMBUS is an opportunity to use the target pointing capabilities from the ISS. The current exposure facilities are also preparing future planetary protection procedures. Other applications have already been previously considered as experimental collision and impact studies in both space vacuum and microgravity. Future space stations at the Lagrange points could simultaneously combine unique observation platforms with an actual intermediate stepping stone to Mars.

Taming Liquid Hydrogen: The Centaur Upper Stage Rocket, 1958-2002

NASA Technical Reports Server (NTRS)

Dawson, Virginia P.; Bowles, Mark D.

2004-01-01

During its maiden voyage in May 1962, a Centaur upper stage rocket, mated to an Atlas booster, exploded 54 seconds after launch, engulfing the rocket in a huge fireball. Investigation revealed that Centaur's light, stainless-steel tank had split open, spilling its liquid-hydrogen fuel down its sides, where the flame of the rocket exhaust immediately ignited it. Coming less than a year after President Kennedy had made landing human beings on the Moon a national priority, the loss of Centaur was regarded as a serious setback for the National Aeronautics and Space Administration (NASA). During the failure investigation, Homer Newell, Director of Space Sciences, ruefully declared: "Taming liquid hydrogen to the point where expensive operational space missions can be committed to it has turned out to be more difficult than anyone supposed at the outset." After this failure, Centaur critics, led by Wernher von Braun, mounted a campaign to cancel the program. In addition to the unknowns associated with liquid hydrogen, he objected to the unusual design of Centaur. Like the Atlas rocket, Centaur depended on pressure to keep its paper-thin, stainless-steel shell from collapsing. It was literally inflated with its propellants like a football or balloon and needed no internal structure to give it added strength and stability. The so-called "pressure-stabilized structure" of Centaur, coupled with the light weight of its high- energy cryogenic propellants, made Centaur lighter and more powerful than upper stages that used conventional fuel. But, the critics argued, it would never become the reliable rocket that the United States needed.

The Moonlandings

NASA Astrophysics Data System (ADS)

Turnill, Reginald

2002-12-01

The Soviet-American race to land the first man on the Moon was a technical challenge unlike anything in modern human history. BBC Aerospace Correspondent Reginald Turnill covered the story, and his reports were heard and seen by millions worldwide. With unparalleled access to the politicians, scientists, and technicians involved in the race to the Moon, Turnill knew all the early astronauts--Alan Shepard, John Glenn, Neil Armstrong, Buzz Aldrin--as they pioneered the techniques that made the Moon landings possible. He became a friend of Dr. Wernher von Braun, the German rocket pioneer and mastermind behind the technology. Turnill's unique eyewitness account of one of the most thrilling adventures of the twentieth century is clearly written and is packed with action and drama, making this a fascinating read for all those interested in the story of the race to the Moon. Reginald Turnill started work in Fleet Street at the age of 15, and by 19 he was covering the national news as a Press Association staff reporter. After joining the BBC in 1956 he covered the launch of Sputnik 1 and found it so exciting that he made space reporting his speciality. As the BBC Aerospace Correspondent, Turnill spent the rest of his career covering all the manned space missions as well as planetary missions like Mariner, Pioneer, Viking, and Voyager. Since leaving the BBC staff, Turnill has continued to broadcast and write on space, and he created the first spaceflight directory. Turnill is the only non-American to have been presented with NASA's Chroniclers Award for contributions to public understanding of the space program.

A rapid method to visualize von willebrand factor multimers by using agarose gel electrophoresis, immunolocalization and luminographic detection.

PubMed

Krizek, D R; Rick, M E

2000-03-15

A highly sensitive and rapid clinical method for the visualization of the multimeric structure of von Willebrand Factor in plasma and platelets is described. The method utilizes submerged horizontal agarose gel electrophoresis, followed by transfer of the von Willebrand Factor onto a polyvinylidine fluoride membrane, and immunolocalization and luminographic visualization of the von Willebrand Factor multimeric pattern. This method distinguishes type 1 from types 2A and 2B von Willebrand disease, allowing timely evaluation and classification of von Willebrand Factor in patient plasma. It also allows visualization of the unusually high molecular weight multimers present in platelets. There are several major advantages to this method including rapid processing, simplicity of gel preparation, high sensitivity to low concentrations of von Willebrand Factor, and elimination of radioactivity.

Why Extra Gauge Bosons Should Exist and How to Hunt Them

NASA Astrophysics Data System (ADS)

Leike, Arnd

2003-09-01

Werner Heisenberg's work is the foundation for many topics of present research. This is also true for the search for extra gauge bosons. The prospects of future colliders in this search are shortly mentioned.

Colds and flus - antibiotics

MedlinePlus

Antibiotics - colds and flu ... treat infections that are caused by a virus. Colds and flu are caused by viruses. If you ... J, Ericson K, Werner S. Treatment of the common cold in children and adults. Am Fam Physician. 2012; ...

The history of Werner Spalteholz's Handatlas der Anatomie des Menschen.

PubMed

Williams, D J

1999-12-01

Werner Spalteholz's Handatlas der Anatomie des Menschen is one of the most elegantly illustrated anatomical atlases of all time. Originally published in Leipzig as three volumes from 1895 to 1903, the atlas is still widely used and remains highly regarded by many. The atlas was remarkably popular during the first half of the 20th century, especially the English version in North America and the UK. Unfortunately, the original illustrations and printing plates for the work disappeared following the Second World War and their fate remains a mystery. And, in spite of the atlas's popularity, little is known to the men who prepared the artwork for Spalteholz. It is commonly believed that Max Brödel contributed illustrations to the atlas, but a close examination of the work does not confirm this. A century after its inception, Spalteholz's atlas remains a classic milestone in the history of anatomical illustration.

SOFIA Science Imagery

NASA Image and Video Library

2017-09-14

SCI2012_0003: SOFIA mid-infrared image of the planetary nebula Minkowski 2-9 (M2-9), also known as the Butterfly Nebula, compared with a visual-wavelength Hubble Space Telescope image at the same scale and orientation. The nebula is composed of two lobes of gas & dust expelled from a dying star with about the mass of our Sun that is seen at the center of the lobes. The HST image shows mostly ionized gas in the lobes whereas the SOFIA image shows mostly solid grains condensing in the gas. The SOFIA data were obtained during SOFIA's Early Science program in 2011 by a Guest Investigator team led by Michael Werner of Caltech/JPL using the FORCAST camera (P.I.Terry Herter, Cornell University). Credit: SOFIA image, RGB = 37, 24, 20 microns; NASA/DLR/USRA/DSI/FORCAST team/M. Werner et al./A. Helton, J. Rho; HST image: NASA/ESA/NSF/AURA/Hubble Heritage Team/STScI/B. Balick, V. Icke, G. Mellema

Book Review: John von Neumann and the foundations of quantum physics. (Vienna Circle Institute yearbook (2000), 8) Miklos Redei and Michael Stoltzner (Eds.); Kluwer Academic Publishers, Dordrecht, 2001, pp., US 125, ISBN 0792368126

NASA Astrophysics Data System (ADS)

Lupher, Tracy

2003-12-01

Some people may be surprised to learn that John von Neumann's work on the foundations of quantum physics went far beyond what is contained within the pages of his Mathematical Foundations of Quantum Mechanics (MFQM) (von Neumann, 1955). However, this narrow focus often ignores von Neumann's later work on quantum logic and what are now called in his honor, von Neumann algebras. This volume honoring von Neumann's contributions to physics is unique in that, while it contains 12 papers that examine various aspects of von Neumann's work, it also contains two of his previously unpublished papers and some of his previously unpublished correspondence.

NASA Chief Technologist Hosts Town Hall

NASA Image and Video Library

2010-05-24

NASA's Chief Technologists, Bobby Braun, hosts a Town Hall meeting to discuss agency-wide technology policy and programs at NASA Headquarters on Tuesday, May 25, 2010, in Washington. Photo Credit: (NASA/Carla Cioffi)

NASA Chief Technologist Hosts Town Hall

NASA Image and Video Library

2010-05-24

Bobby Braun, NASA's Chief Technologist, is seen on a video monitor during a Town Hall meeting to discuss agency-wide technology policy and programs at NASA Headquarters on Tuesday, May 25, 2010, in Washington. Photo Credit: (NASA/Carla Cioffi)

Invasive forstliche schad-organismen in Nordamerika

Treesearch

Christopher J. Fettig; Horst E.  Delb

2017-01-01

In Nordamerika sind Wälder infolge von Einwandernden, internationalem Handel und Tourismus traditionell stark von Einschleppungen gebietsfremder invasiver Schadorganismen betroffen. Infolge von Globalisierung und Klimawandel gibt es aufgrund der Ähnlichkeiten von Klima, Flora und Fauna zwischen Europa und Nordamerika viele Parallelen.

Werner complex deficiency in cells disrupts the Nuclear Pore Complex and the distribution of lamin B1.

PubMed

Li, Zhi; Zhu, Yizhou; Zhai, Yujia; R Castroagudin, Michelle; Bao, Yifei; White, Tommy E; Glavy, Joseph S

2013-12-01

From the surrounding shell to the inner machinery, nuclear proteins provide the functional plasticity of the nucleus. This study highlights the nuclear association of Pore membrane (POM) protein NDC1 and Werner protein (WRN), a RecQ helicase responsible for the DNA instability progeria disorder, Werner Syndrome. In our previous publication, we connected the DNA damage sensor Werner's Helicase Interacting Protein (WHIP), a binding partner of WRN, to the NPC. Here, we confirm the association of the WRN/WHIP complex and NDC1. In established WRN/WHIP knockout cell lines, we further demonstrate the interdependence of WRN/WHIP and Nucleoporins (Nups). These changes do not completely abrogate the barrier of the Nuclear Envelope (NE) but do affect the distribution of FG Nups and the RAN gradient, which are necessary for nuclear transport. Evidence from WRN/WHIP knockout cell lines demonstrates changes in the processing and nucleolar localization of lamin B1. The appearance of "RAN holes" void of RAN corresponds to regions within the nucleolus filled with condensed pools of lamin B1. From WRN/WHIP knockout cell line extracts, we found three forms of lamin B1 that correspond to mature holoprotein and two potential post-translationally modified forms of the protein. Upon treatment with topoisomerase inhibitors lamin B1 cleavage occurs only in WRN/WHIP knockout cells. Our data suggest the link of the NDC1 and WRN as one facet of the network between the nuclear periphery and genome stability. Loss of WRN complex leads to multiple alterations at the NPC and the nucleolus. © 2013. Published by Elsevier B.V. All rights reserved.

Heisenberg and the critical mass

NASA Astrophysics Data System (ADS)

Bernstein, Jeremy

2002-09-01

An elementary treatment of the critical mass used in nuclear weapons is presented and applied to an analysis of the wartime activities of the German nuclear program. In particular, the work of Werner Heisenberg based on both wartime and postwar documents is discussed.

Genetics and aging; the Werner syndrome as a segmental progeroid syndrome.

PubMed

Martin, G M

1985-01-01

The maximum lifespan potential is a constitutional feature of speciation and must be subject to polygenic controls acting both in the domain of development and in the domain of the maintenance of macromolecular integrity. The enormous genetic heterogeneity that characterizes our own species, the complexities of numerous nature-nurture interactions, and the quantitative and qualitative variations of the senescent phenotype that are observed suggest that precise patterns of aging in each of us may be unique. Patterns of aging may also differ sharply among species (for example, semelparous vs. multiparous mammals). Some potential common denominators, however, allow one to identify progeroid syndromes in man that could lead to the elucidation of important pathways of gene action. (The suffix "-oid" means "like"; it does not mean identity.) Unimodal progeroid syndromes (eg., familial dementia of the Alzheimer type, an autosomal dominant) can help us understand the pathogenesis of a particular aspect of the senescent phenotype of man. Segmental progeroid syndromes (eg. the Werner syndrome, an autosomal recessive) may be relevant to multiple aspects of the senescent phenotype. Some results of research on the Werner syndrome may be interpreted as support for "peripheral" as opposed to "central" theories of aging; they are consistent with the view that gene action in the domain of development (adolescence, in this instance) can set the stage for patterns of aging in the adult; they point to the importance of mesenchymal cell populations in the pathogenesis of age-related disorders; finally, they underscore the role of chromosomal instability, especially in the pathogenesis of neoplasia.

GENERAL: Thermal entanglement and teleportation of a thermally mixed entangled state of a Heisenberg chain through a Werner state

NASA Astrophysics Data System (ADS)

Huang, Li-Yuan; Fang, Mao-Fa

2008-07-01

The thermal entanglement and teleportation of a thermally mixed entangled state of a two-qubit Heisenberg XXX chain under the Dzyaloshinski-Moriya (DM) anisotropic antisymmetric interaction through a noisy quantum channel given by a Werner state is investigated. The dependences of the thermal entanglement of the teleported state on the DM coupling constant, the temperature and the entanglement of the noisy quantum channel are studied in detail for both the ferromagnetic and the antiferromagnetic cases. The result shows that a minimum entanglement of the noisy quantum channel must be provided in order to realize the entanglement teleportation. The values of fidelity of the teleported state are also studied for these two cases. It is found that under certain conditions, we can transfer an initial state with a better fidelity than that for any classical communication protocol.

Interference Lithography for Optical Devices and Coatings

DTIC Science & Technology

2010-01-01

semiconductor quantum dots. J. Chem. Phys. 2004, 121, 7421. 100. Jeon, S.; Braun, P. V., Hydrothermal Synthesis of Er-Doped Luminescent TiO2 Nanoparticles ...Silica Nanoparticle Synthesis .....................................................................23 2.2.2 Polymer Matrix Formulation...41 CHAPTER 3: NANOPARTICLE SYNTHESIS , FUNCTIONALIZATION, AND INCORPORATION INTO

76 FR 75942 - Qualification of Drivers; Exemption Applications; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-05

... renewable two-year period. They are: Anthony Brandano (MA) William R. Braun (NM) Stanley E. Elliott (UT.... Mallory (OK) Eldon Miles (IN) Norman V. Myers (WA) Jack E. Potts, Jr. (PA) Neal A. Richard (LA) John E...

Abraham Pais Prize Talk: The Joy of History

NASA Astrophysics Data System (ADS)

Stuewer, Roger H.

2013-04-01

Physicists and historians of physics share a common goal, the quest for understanding, but their objects are different: Physicists attempt to understand Nature, while historians attempt to understand the past, finding both the challenge and joy of history in exploring the contingencies of historical events, their dependence on scientific, biographical, sociopolitical, cultural, and other factors, and shaping them into a coherent narrative. My first example will focus on the history of the photon concept, in particular on the work of Arthur Holly Compton between 1916 and 1922 that led to his discovery of the Compton effect, whose understanding ultimately rested on a close examination of his laboratory notebooks. I will then turn to two episodes in the history of nuclear physics. The first deals with a controversy between 1922 and 1927 between Ernest Rutherford and James Chadwick at the Cavendish Laboratory in Cambridge and Hans Pettersson and Gerhard Kirsch at the Institute for Radium Research in Vienna that involved their fundamentally different experimental observations and theoretical interpretations of the artificial disintegration of nuclei whose resolution could only be understood after uncovering crucial correspondence between the protagonists. The second episode traces George Gamow's creation and development of the liquid-drop model of the nucleus in 1928 and 1929 and its subsequent development in two stages, first by Werner Heisenberg and Carl Friedrich von Weizsäcker from 1933 to 1936, and second by Niels Bohr and Fritz Kalckar in 1936 and 1937, both of which merged in the minds of Lise Meitner and Otto Robert Frisch at the end of 1938 to yield the correct interpretation of nuclear fission, an act of creation whose understanding rested on a detailed analysis of the published literature.

Liquid Biopsy zur Überwachung von Melanompatienten.

PubMed

Gaiser, Maria Rita; von Bubnoff, Nikolas; Gebhardt, Christoffer; Utikal, Jochen Sven

2018-04-01

In den letzten sechs Jahren wurden verschiedene innovative systemische Therapien zur Behandlung des metastasierten malignen Melanoms (MM) entwickelt. Die konventionelle Chemotherapie wurde durch neuartige Primärtherapien abgelöst, darunter systemische Immuntherapien (Anti-CTLA4- und Anti-PD1-Antikörper; Zulassung von Anti-PDL1-Antikörpern erwartet) und Therapien, die gegen bestimmte Mutationen gerichtet sind (BRAF, NRAS und c-KIT). Daher stehen die behandelnden Ärzte neuen Herausforderungen gegenüber, beispielsweise der Stratifizierung von Patienten für geeignete Behandlungen und der Überwachung von Langzeit-Respondern auf Progression. Folglich werden zuverlässige Methoden zur Überwachung von Krankheitsprogression oder Behandlungsresistenz benötigt. Lokalisierte und fortgeschrittene Krebserkrankungen können zur Bildung zirkulierender Tumorzellen und Tumor-DNA (ctDNA) führen, die sich in Proben von peripherem Blut nachweisen und quantifizieren lassen (Liquid Biopsy). Im Fall von Melanompatienten können die Ergebnisse von Liquid Biopsy als neuartige prädiktive Biomarker bei therapeutischen Entscheidungen hilfreich sein, insbesondere im Zusammenhang mit mutationsbasierten zielgerichteten Therapien. Die Herausforderungen bei der Anwendung der Liquid Biopsy beinhalten strikte Kriterien für den Phänotyp der zirkulierenden MM-Zellen oder ihrer Fragmente und die Instabilität von ctDNA im Blut. In diesem Übersichtsartikel diskutieren wir die Beschränkungen der Liquid Biopsy hinsichtlich ihrer Anwendung in der Routinediagnostik. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Biological Sensors Using DNA Functionalized Multiwalled Carbon Nanotubes

DTIC Science & Technology

2009-10-01

BIOLOGICAL SENSORS USING DNA FUNCTIONALIZED MULTIWALLED CARBON NANOTUBES S. Ganguly, A. Leela Mohana Reddy and S. Ramaprabhu Alternative...Braun, E. Science 2003, 302, 1380. 9. Leela Mohana Reddy, A.; Shaijumon, M. M.; Ramaprabhu, S. Nanotechnology 2006, 17, 5299. 10. Kovtyukhova, N

Microwave-Assisted Synthesis of a MK2 Inhibitor by Suzuki-Miyaura Coupling for Study in Werner Syndrome Cells.

PubMed

Bagley, Mark C; Baashen, Mohammed; Chuckowree, Irina; Dwyer, Jessica E; Kipling, David; Davis, Terence

2015-06-03

Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2) inhibitors to study accelerated aging in Werner syndrome (WS) cells, including the cross-coupling of a 2-chloroquinoline with a 3-pyridinylboronic acid, the coupling of an aryl bromide with an indolylboronic acid and the reaction of a 3-amino-4-bromopyrazole with 4-carbamoylphenylboronic acid. In all of these processes, the Suzuki-Miyaura reaction was fast and relatively efficient using a palladium catalyst under microwave irradiation. The process was incorporated into a rapid 3-step microwave-assisted method for the synthesis of a MK2 inhibitor involving 3-aminopyrazole formation, pyrazole C-4 bromination using N-bromosuccinimide (NBS), and Suzuki-Miyaura cross-coupling of the pyrazolyl bromide with 4-carbamoylphenylboronic acid to give the target 4-arylpyrazole in 35% overall yield, suitable for study in WS cells.

A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies

PubMed Central

Agrelo, Ruben; Sutz, Miguel Arocena; Setien, Fernando; Aldunate, Fabian; Esteller, Manel; Da Costa, Valeria; Achenbach, Ricardo

2015-01-01

Werner Syndrome (WS) is a rare inherited disease characterized by premature aging and increased propensity for cancer. Mutations in the WRN gene can be of several types, including nonsense mutations, leading to a truncated protein form. WRN is a RecQ family member with both helicase and exonuclease activities, and it participates in several cell metabolic pathways, including DNA replication, DNA repair, and telomere maintenance. Here, we reported a novel homozygous WS mutation (c.3767 C > G) in 2 Argentinian brothers, which resulted in a stop codon and a truncated protein (p.S1256X). We also observed increased WRN promoter methylation in the cells of patients and decreased messenger WRN RNA (WRN mRNA) expression. Finally, we showed that the read-through of nonsense mutation pharmacologic treatment with both aminoglycosides (AGs) and ataluren (PTC-124) in these cells restores full-length protein expression and WRN functionality. PMID:25830902

Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.

PubMed

Zhang, Weiqi; Li, Jingyi; Suzuki, Keiichiro; Qu, Jing; Wang, Ping; Zhou, Junzhi; Liu, Xiaomeng; Ren, Ruotong; Xu, Xiuling; Ocampo, Alejandro; Yuan, Tingting; Yang, Jiping; Li, Ying; Shi, Liang; Guan, Dee; Pan, Huize; Duan, Shunlei; Ding, Zhichao; Li, Mo; Yi, Fei; Bai, Ruijun; Wang, Yayu; Chen, Chang; Yang, Fuquan; Li, Xiaoyu; Wang, Zimei; Aizawa, Emi; Goebl, April; Soligalla, Rupa Devi; Reddy, Pradeep; Esteban, Concepcion Rodriguez; Tang, Fuchou; Liu, Guang-Hui; Belmonte, Juan Carlos Izpisua

2015-06-05

Werner syndrome (WS) is a premature aging disorder caused by WRN protein deficiency. Here, we report on the generation of a human WS model in human embryonic stem cells (ESCs). Differentiation of WRN-null ESCs to mesenchymal stem cells (MSCs) recapitulates features of premature cellular aging, a global loss of H3K9me3, and changes in heterochromatin architecture. We show that WRN associates with heterochromatin proteins SUV39H1 and HP1α and nuclear lamina-heterochromatin anchoring protein LAP2β. Targeted knock-in of catalytically inactive SUV39H1 in wild-type MSCs recapitulates accelerated cellular senescence, resembling WRN-deficient MSCs. Moreover, decrease in WRN and heterochromatin marks are detected in MSCs from older individuals. Our observations uncover a role for WRN in maintaining heterochromatin stability and highlight heterochromatin disorganization as a potential determinant of human aging. Copyright © 2015, American Association for the Advancement of Science.

Identification of a His54Gln substitution in von Willebrand factor from a patient with defective binding of factor VIII.

PubMed

Rick, M E; Krizek, D M

1996-04-01

A patient with type 2N ("Normandy" variant) von Willebrand's disease is described. Her von Willebrand factor level was borderline low, while her factor VIII was markedly decreased to 7%. Her plasma von Willebrand factor demonstrated a decreased ability to complex with factor VIII in vitro, binding less than 10% when compared to normal plasma von Willebrand factor. The factor VIII released into the circulation after the patient received DDAVP had a shortened survival in vivo. Nucleotide sequence analysis revealed a T-to-A transition at nucleotide 2451 on both alleles. This transition results in a substitution of Gln for His at amino acid 54 in the mature subunit of von Willebrand factor.

Making a Difference: Innovations in Adult Education.

ERIC Educational Resources Information Center

Mauch, Werner, Ed.; Papen, Uta, Ed.

This book highlights examples of innovative educational practices in the field of organized adult learning. Fifteen chapters present outcomes of collective research in the Innovations in Nonformal and Adult Education (INNAE) project. "Common Learning--Collective Research: Innovating Adult Education" (Werner Mauch, Uta Papen) describes the…

Clarifying the link between von Neumann and thermodynamic entropies

NASA Astrophysics Data System (ADS)

Deville, Alain; Deville, Yannick

2013-01-01

The state of a quantum system being described by a density operator ρ, quantum statistical mechanics calls the quantity - kTr( ρln ρ), introduced by von Neumann, its von Neumann or statistical entropy. A 1999 Shenker's paper initiated a debate about its link with the entropy of phenomenological thermodynamics. Referring to Gibbs's and von Neumann's founding texts, we replace von Neumann's 1932 contribution in its historical context, after Gibbs's 1902 treatise and before the creation of the information entropy concept, which places boundaries into the debate. Reexamining von Neumann's reasoning, we stress that the part of his reasoning implied in the debate mainly uses thermodynamics, not quantum mechanics, and identify two implicit postulates. We thoroughly examine Shenker's and ensuing papers, insisting upon the presence of open thermodynamical subsystems, imposing us the use of the chemical potential concept. We briefly mention Landau's approach to the quantum entropy. On the whole, it is shown that von Neumann's viewpoint is right, and why Shenker's claim that von Neumann entropy "is not the quantum-mechanical correlate of thermodynamic entropy" can't be retained.

Designing for the Edge of Space and Beyond

NASA Technical Reports Server (NTRS)

Jenkins, Dennis R.

2003-01-01

Despite the fanciful predictions of Eugen Sanger, Wernher von Braun, and a wealth of science fiction novelists, it was not until the mid-1950s that the first piloted spacecraft design was undertaken in earnest. It was the height of the Cold War, and the paranoia that swept the country and the military had resulted in the largest arms race the world had ever seen. In aviation the desire was to go higher, faster, and farther than ever before. In response to a need for basic research into the ever-increasing speeds and altitudes, the National Advisory Committee on Aeronautics (NACA) began preliminary research into a piloted vehicle that could exceed five times the speed of sound. The research was felt necessary to support both unmanned missile programs and the eventual development of hypersonic combat aircraft. Interestingly, the group of researchers that took the lead in developing the concept (led by John V. Becker) at the NACA s Langley Laboratory added a new wrinkle-they wanted to be able to leave the sensible atmosphere for a few minutes in order to gain a preliminary understanding of space flight2 At the time it was generally felt that piloted space flight would not take place until the turn of the century, although contemporary science fiction-a genre that enjoyed a resurgence of popularity in the mid-1 950s-usually showed it coming much earlier. In fact, many serious researchers believed that the group at Langley should remove the "space leap" from their concept for a hypersonic research airlane. However, the basic designs for a very high speed airplane and for one capable of short excursions outside the atmosphere were not radically different, so the capability remained.

Bernard Lerer: Recipient of the 2014 Inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics)

PubMed Central

Aynacıoğlu, Şükrü; Bragazzi, Nicola Luigi; Dandara, Collet; Dove, Edward S.; Ferguson, Lynnette R.; Geraci, Christy Jo; Hafen, Ernst; Kesim, Belgin Eroğlu; Kolker, Eugene; Lee, Edmund J.D.; LLerena, Adrian; Nacak, Muradiye; Shimoda, Kazutaka; Someya, Toshiyuki; Srivastava, Sanjeeva; Tomlinson, Brian; Vayena, Effy; Warnich, Louise; Yaşar, Ümit

2014-01-01

Abstract This article announces the recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine by the Pacific Rim Association for Clinical Pharmacogenetics (PRACP): Bernard Lerer, professor of psychiatry and director of the Biological Psychiatry Laboratory, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. The Werner Kalow Responsible Innovation Prize is given to an exceptional interdisciplinary scholar who has made highly innovative and enduring contributions to global omics science and personalized medicine, with both vertical and horizontal (transdisciplinary) impacts. The prize is established in memory of a beloved colleague, mentor, and friend, the late Professor Werner Kalow, who cultivated the idea and practice of pharmacogenetics in modern therapeutics commencing in the 1950s. PRACP, the prize's sponsor, is one of the longest standing learned societies in the Asia-Pacific region, and was founded by Kalow and colleagues more than two decades ago in the then-emerging field of pharmacogenetics. In announcing this inaugural prize and its winner, we seek to highlight the works of prize winner, Professor Lerer. Additionally, we contextualize the significance of the prize by recalling the life and works of Professor Kalow and providing a brief socio-technical history of the rise of pharmacogenetics and personalized medicine as a veritable form of 21st century scientific practice. The article also fills a void in previous social science analyses of pharmacogenetics, by bringing to the fore the works of Kalow from 1995 to 2008, when he presciently noted the rise of yet another field of postgenomics inquiry—pharmacoepigenetics—that railed against genetic determinism and underscored the temporal and spatial plasticity of genetic components of drug response, with invention of the repeated drug administration (RDA) method that estimates the dynamic heritabilities of drug response. The prize goes a long way to cultivate transgenerational capacity and broader cognizance of the concept and practice of responsible innovation as an important criterion of 21st century omics science and personalized medicine. A new call is presently in place for the 2016 PRACP Werner Kalow prize. Nominations can be made in support of an exceptional individual interdisciplinary scholar, or alternatively, an entire research team, from any region in the world with a record of highly innovative contributions to global omics science and/or personalized medicine, in the spirit of responsible innovation. The application process is straightforward, requiring a signed, 1500-word nomination letter (by the applicant or sponsor) submitted not later than May 31, 2015. Wanderer, your footsteps are the road, and nothing more; wanderer, there is no road, the road is made by walking. By walking one makes the road, and upon glancing behind one sees the path that never will be trod again. Wanderer, there is no road – Only wakes upon the sea. Antonio Machado (1875–1939) “The real voyage of discovery consists not in seeking new landscapes but in having new eyes.” Marcel Proust (1871–1922) PMID:24649998

Spirit's 'Paige' Panorama of the Interior of 'Home Plate'

NASA Technical Reports Server (NTRS)

2006-01-01

[figure removed for brevity, see original site] Click on the image for Spirit's 'Paige' Panorama of the Interior of 'Home Plate' (QTVR)

On Feb. 19, 2006, the 758th Martian day of exploration of the red planet by NASA's Mars Exploration Rover Spirit, the rover acquired this panoramic view of the interior of 'Home Plate,' a circular topographic feature amid the 'Columbia Hills.' This view, called the 'Paige' panorama, is from the top of Home Plate. It shows layered rocks exposed at the edge as well as dark rocks exhibiting both smooth and sponge-like 'scoriaceous' textures. To the east from this vantage point, 'McCool Hill' looms on the horizon. At the base of McCool Hill is a reddish outcrop called 'Oberth,' which Spirit may explore during the rapidly approaching Martian winter. 'Von Braun' and 'Goddard' hills are partially visible beyond the opposite rim of Home Plate.

The limited spatial coverage of this panorama is the result of steadily decreasing power available to the rover for science activities as the Martian winter arrives and the sun traces a lower path across the sky. The rover team anticipates that the north-facing slopes of McCool Hill should sufficiently tilt the rover's solar panels toward the sun to allow Spirit to survive the winter.

The view covers about 230 degrees of terrain around the rover. Spirit's panoramic camera (Pancam) took 72 separate images of this scene with four different Pancam filters. This is an approximately true-color rendering using the Pancam's 75-nanometer, 535-nanometer, and 432-nanometer filters. Image-to-image seams have been eliminated from the sky portion of the mosaic to better simulate the vista a person standing on Mars would see.

Studies of Circulatory and Metabolic Changes during Ketamine Narcosis,

DTIC Science & Technology

1985-03-13

Braun, U., Hensel, I., Kettler, D., Lohr, B.: The effects of methoxyflurane , halothane, dipiritramide, barbiturate and ketamine on the total oxygen...narcosis caus- ed by ether, halothane, methoxyflurane , ketamine and piritranide, as well as neuroleptanalgesia. Lecture at the XIIth. General Con

Gebrauch von Komplementärmedizin bei Patienten mit metastasierendem Melanom unter Therapie mit Ipilimumab innerhalb einer klinischen Studie.

PubMed

Huebner, Jutta; Mohr, Peter; Simon, Jan-Christoph; Fluck, Michael; Berking, Carola; Zimmer, Lisa; Loquai, Carmen

2016-05-01

In Deutschland wenden 40-90 % aller Krebspatienten Methoden der komplementären and alternativen Medizin (KAM) an. Bis dato gibt es kein Datenmaterial zum Einsatz der KAM bei Melanompatienten. Das Ziel unserer Studie war es, Daten über den Gebrauch, die Informationsquellen und Ziele von Patienten mit metastasierendem Melanom zu erfassen. Einhundertsechsundfünfzig Patienten aus 25 Studienzentren nahmen an der DecOG-MM-PAL Multibasket Studie teil. Die beteiligten Personen wurden auch gebeten, an einer Nebenstudie teilzunehmen, die ihren Gebrauch von KAM erfassen sollte. Dazu wurde während der Behandlung ein standardisierter Fragebogen zu genau festgelegten Zeitpunkten ausgeteilt. Insgesamt gingen 55 Fragebögen von 32 (21 %) Melanompatienten ein. Von diesen gaben 17 (53 %) ein Interesse an KAM an, und sieben (22 %) machten von KAM Gebrauch. Die Hauptinformationsquellen (31 %) waren Familienmitglieder und Freunde, gefolgt von Ärzten (19 %). Die Hauptgründe für die Anwendung von KAM waren die Stärkung des Immunsystems (41 %) und des Körpers (34 %). Nahrungsergänzungsmittel (Vitamine und Spurenelemente) wurden am häufigsten angewendet (28 %). Eine relativ hohe Anzahl an Patienten mit metastasierendem Melanom machte trotz Teilnahme an einer klinischen Studie von KAM Gebrauch. Wechselwirkungen könnten durch biologisch basierte KAM auftreten, und hier besonders bei immunmodulierenden KAM- Strategien. Um Risiken zu vermeiden, sollte die Kommunikation zwischen den Ärzten und den Patienten verbessert werden. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Strategies for High-Resolution 3-D Millimeter Wave Imaging.

DTIC Science & Technology

1987-02-01

Co-Investigator K.S. Lee - Graduate Student (50%) P. Frangos - Graduate Student (50%) Y. Shen - Graduate Student (50%) K. Schultz - Graduate...period of this report: * P. Frangos (Ph.D.) - "One-Dinensionl Inverse Scattering: Exact Methods and Applications", * C.L. Werner (Ph.D.) - ŗ-D

Havens of Resilience

ERIC Educational Resources Information Center

Henderson, Nan

2013-01-01

Schools are natural environments for helping all children cultivate the resilience that resides within them. Research shows that schools are filled with the conditions that promote resilience (Werner, 2003). These include caring, encouraging relationships, role models, and mentors (Theron & Engelbrecht, 2012; Thomsen, 2002; Walsh, 2012); clear…

Bridging the timescales between thermochronological and cosmogenic nuclide data

NASA Astrophysics Data System (ADS)

Glotzbach, Christoph

2015-04-01

Reconstructing the evolution of Earth's landscape is a key to understand its future evolution and to identify the driving forces that shape Earth's surface. Cosmogenic nuclide and thermochronological methods are routinely used to quantify Earth surface processes over 102-104 yr and 106-107 yr, respectively (e.g. Lal 1991; Reiners and Ehlers 2005; von Blanckenburg 2006). A comparison of the rates of surface processes derived from these methods is, however, hampered by the large difference in their timescales. For instance, a constant erosion rate of 0.1 mm/yr yield an apatite (U-Th)/He age of ~24 Ma and a 10Be age of ~6 ka, respectively. Analytical methods that bridge this time gap are on the way, but are not yet fully established (e.g. Herman et al. 2010). A ready to use alternative are river profiles, which record the regional uplift history over 102-107 yr (e.g. Pritchard et al. 2009). Changes in uplift are retained in knickzones that propagate with a distinct velocity upstream, and therefore the time of an uplift event can be estimated. Here I present an integrative inverse modelling approach to simultaneously reconstruct river profiles, model thermochronological and cosmogenic nuclide data and to derive robust information about landscape evolution over thousands to millions of years. An efficient inversion routine is used to solve the forward problem and find the best uplift history and erosional parameters that reproduce the observed data. I test the performance of the algorithm by inverting a synthetic dataset and a dataset from the Sila massif (Italy). Results show that even complicated uplift histories can be reliably retrieved by the combined interpretation of river profiles, thermochronological and cosmogenic nuclide data. References Gallagher, K., Brown, R. & Johnson, C. (1998): Fission track analysis and its applications to geological problems. - Annu. Rev. Earth Planet., 26: 519-572. Herman, F., Rhodes, E.J., Braun, J. & Heiniger, L. (2010): Uniform erosion rates and relief amplitude during glacial cycles in the Southern Alps of New Zealand, as revealed from OSL-thermochronology. - Earth Planet. Sci. Lett., 297: 183-189. Lal, D. (1991): Cosmic ray labeling of erosion surfaces: in situ nuclide production rates and erosion models. - Earth Planet. Sci. Lett. 104: 424-439. Pritchard, D., Roberts, G.G., White, N.J. & Richardson, C.N. (2009): Uplift histories from river profiles. - Geophys. Res. Lett., 36, L24301, doi:10.1029/2009GL040928. Reiners, P.W. & Ehlers, T.A. (2005): Low-temperature Thermochronology: Techniques, Interpretations, and Applications. - Rev. Mineral. Geochem., 58. Von Blanckenburg, F. (2006): The control mechanisms of erosion and weathering at basin scale from cosmogenic nuclides in river sediment. - Earth Planet. Sci. Lett., 242: 462-479.

Ein Konzept für den energieeffizienten Betrieb von Mobilfunknetzen

NASA Astrophysics Data System (ADS)

Bayer, N.; von Hugo, D.

2015-11-01

Der flächendeckende Betrieb mehrerer Mobilfunknetze unterschiedlicher Technologie in einem Land sorgt aufgrund der ständigen Bereithaltung von Übertragungskapazität für Dienste mit zunehmend höherem Datenvolumenbedarf für einen erheblichen Energieverbrauch. Das Forschungsförderungsprojekt ComGreen hat sich zur Aufgabe gesetzt, durch lastadaptiven Betrieb und intelligente dynamische Rekonfiguration des Funkzugangsnetzes zur Energieeinsparung beizutragen. Konzept, Herausforderungen, ausgewählte Ergebnisse von Simulationen und prototypischem Betrieb werden ebenso wie typische Erwartungswerte des künftigen Energieverbrauchs im Mobilfunkbereich vorgestellt. Sowohl Berechnungen als auch Messungen zeigen, dass durch kontext-basierte dynamische Rekonfiguration von zellularen Funknetzen Energieeinsparungen im Bereich von 25-40 % ermöglicht werden.

q-Deformed Minkowski Algebra and Its Space-Time Lattice

NASA Astrophysics Data System (ADS)

Wess, J.

2Max-Planck-Institut für Physik (Werner-Heisenberg-Institut) Föhringer Ring 6, D-80805 MünchenAbstract. We have asked how the Heisenberg relations of space and time change if we replace the Lorentz group by a q-deformed Lorentz group (Lorek et al. 1997).

Parametric source of two-photon states with a tunable degree of entanglement and mixing: Experimental preparation of Werner states and maximally entangled mixed states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cinelli, C.; Di Nepi, G.; De Martini, F.

2004-08-01

A parametric source of polarization-entangled photon pairs with striking spatial characteristics is reported. The distribution of the output electromagnetic k modes excited by spontaneous parametric down-conversion and coupled to the output detectors can be very broad. Using these states realized over a full entanglement ring output distribution, the nonlocal properties of the generated entanglement have been tested by standard Bell measurements and by Ou-Mandel interferometry. A 'mode-patchwork' technique based on the quantum superposition principle is adopted to synthesize in a straightforward and reliable way any kind of mixed state, of large conceptual and technological interest in modern quantum information. Tunablemore » Werner states and maximally entangled mixed states have indeed been created by this technique and investigated by quantum tomography. A study of the entropic and nonlocal properties of these states has been undertaken experimentally and theoretically, by a unifying variational approach.« less

Quantum discord with weak measurement operators of quasi-Werner states based on bipartite entangled coherent states

NASA Astrophysics Data System (ADS)

Castro, E.; Gómez, R.; Ladera, C. L.; Zambrano, A.

2013-11-01

Among many applications quantum weak measurements have been shown to be important in exploring fundamental physics issues, such as the experimental violation of the Heisenberg uncertainty relation and the Hardy paradox, and have also technological implications in quantum optics, quantum metrology and quantum communications, where the precision of the measurement is as important as the precision of quantum state preparation. The theory of weak measurement can be formulated using the pre-and post-selected quantum systems, as well as using the weak measurement operator formalism. In this work, we study the quantum discord (QD) of quasi-Werner mixed states based on bipartite entangled coherent states using the weak measurements operator, instead of the projective measurement operators. We then compare the quantum discord for both kinds of measurement operators, in terms of the entanglement quality, the latter being measured using the concept of concurrence. It's found greater quantum correlations using the weak measurement operators.

Die nuklearen Anlagen von Hanford (1943-1987) Eine Fallstudie über die Schnittstellen von Physik, Biologie und die US-amerikanische Gesellschaft zur Zeit des Kalten Krieges

NASA Astrophysics Data System (ADS)

Macuglia, Daniele

Die Geschichte des Kalten Krieges eröffnet viele Möglichkeiten, sich näher mit den Schnittstellen von Physik und Biologie während des 20. Jahrhunderts zu befassen. Nicht nur das Unglück in Tschernobyl aus dem Jahr 1986, auch das Beispiel der nuklearen Anlagen in Hanford in den Vereinigten Staaten zeigt die biologischen Folgen von nuklearer Physik.

Monte Carlo turbulence simulation using rational approximations to von Karman spectra

NASA Technical Reports Server (NTRS)

Campbell, C. W.

1986-01-01

Turbulence simulation is computationally much simpler using rational spectra, but turbulence falls off as f exp -5/3 in frequency ranges of interest to aircraft response and as predicted by von Karman's model. Rational approximations to von Karman spectra should satisfy three requirements: (1) the rational spectra should provide a good approximation to the von Karman spectra in the frequency range of interest; (2) for stability, the resulting rational transfer function should have all its poles in the left half-plane; and (3) at high frequencies, the rational spectra must fall off as an integer power of frequency, and since the -2 power is closest to the -5/3 power, the rational approximation should roll off as the -2 power at high frequencies. Rational approximations to von Karman spectra that satisfy these three criteria are presented, along with spectra from simulated turbulence. Agreement between the spectra of the simulated turbulence and von Karman spectra is excellent.

von Willebrand's disease antigen II. A new plasma and platelet antigen deficient in severe von Willebrand's disease.

PubMed Central

Montgomery, R R; Zimmerman, T S

1978-01-01

Factor VIII-related antigen (VIIIag) is deficient in plasma and platelets of patients with severe von Willebrand's disease. This study reports a second von Willebrand's disease antigen (vWagII), distinct from VIIIag, that is also deficient in the platelets and plasma of patients with severe von Willebrand's disease. VIIIag and vWagII are separable by molecular exclusion chromatography, sucrose density gradient ultracentrifugation, and crossed immunoelectrophoresis. They show reactions of immunologic nonidentity with each other, and thus, do not share a precursor-product relationship. vWagII is released from normal platelets during blood clotting, accounting for a fourfold higher concentration of vWagII in serum over plasma. Images PMID:307007

The Social Relevance of Montessori in the First Plane

ERIC Educational Resources Information Center

Andrews, Sarah Werner

2015-01-01

This article represents an amazing reversal of linguistic analysis. Usually Montessori language is translated into "state" terminology. In this case, Sarah Werner Andrews puts state quality assessment terms into Montessori language. For example, domains for school readiness include 1) physical wellbeing and motor development, 2) social…

New Light on Copenhagen and the German Nuclear Project

NASA Astrophysics Data System (ADS)

Cassidy, David C.

The recent release of draft letters from Niels Bohr to Werner Heisenberg provides new insights into German fission research during World War II and into the reasons for its relative failure. I refute claims of deliberate failure and briefly summarize other contributing factors.

Unification of Fundamental Forces

NASA Astrophysics Data System (ADS)

Salam, Abdus; Taylor, Foreword by John C.

2005-10-01

Foreword John C. Taylor; 1. Unification of fundamental forces Abdus Salam; 2. History unfolding: an introduction to the two 1968 lectures by W. Heisenberg and P. A. M. Dirac Abdus Salam; 3. Theory, criticism, and a philosophy Werner Heisenberg; 4. Methods in theoretical physics Paul Adrian Maurice Dirac.

Ultraviolet spectroscopy of the Jovian and Saturnian auroras

NASA Technical Reports Server (NTRS)

Durrance, S. T.; Feldman, P. D.; Moos, H. W.

1982-01-01

The results of a series of IUE observations of the north polar aurora obtained during a substantial fraction of one complete rotation of Jupiter are presented. From these data a spectrum of the aurora with high signal to noise ratio, and a resolution of about 8 A was obtained, making possible the identification of many H2 Lyman and Werner bands. The spectrum is of sufficient quality to provide reliable quantative data for a comparison with the model atmosphere calculations. The lack of an observable absorption signature makes it possible to set an upper limit on the column density of CH4 and C2H6 above the auroral emissions and hence an upper limit on the primary particle energies. A comparison of this spectrum with a laboratory spectrum of discharge excited H2 shows a remarkable similarity. The results of several IUE observations of the full disk of Saturn are also examined. The exposures were of approximately 2 hours each, and the H2 Lyman and Werner bands were observed near the north pole in two of them.

The spectrum of the Jovian dayglow observed at 3 A resolution with the Hopkins ultraviolet telescope

NASA Technical Reports Server (NTRS)

Feldman, P. D.; Mcgrath, M. A.; Moos, H. W.; Durrance, S. T.; Strobel, D. F.; Davidsen, A. F.

1993-01-01

Ultraviolet spectra of the Jovian equatorial dayglow in the spectral range 830-1850 A were obtained at about 3 A resolution. The observed spectrum is dominated by electron impact excitation of the H2 Lyman and Werner band systems. Solar Lyman-beta induced fluorescence in the (6, nu-double prime) Lyman band progression is clearly identified in five distinct P(1) lines, and the contribution of solar fluorescence to the total 2.3 kR slit-averaged H2 emission rate is estimated to be 17-22 percent. The electron excitation spectrum is characterized by a relative weakness of the Werner band system and the absence of cascade contributions to the Lyman system and is very similar to that of the south polar aurora. The integrated H2 emission rate in the 900-1100 A band is a factor of two lower than that measured by the Voyager UVS. Based on model calculations, photoelectron excitation does not appear able to account for the amount of observed electron-excited H2 emission.

Werner's Relevance for Contemporary Developmental Psychology.

ERIC Educational Resources Information Center

Glick, Joseph A.

1992-01-01

Considers the contributions of Heinz Werner to developmental psychology and identifies the tensions between Werner's theory and the practices of contemporary developmental psychology. Core issues of Werner's psychology concern: (1) development as heuristic, rather than phenomenon; (2) developmental process analysis; and (3) conceptions of the…

Spirit's 'Paige' Panorama of the Interior of 'Home Plate' (False Color)

NASA Technical Reports Server (NTRS)

2006-01-01

On Feb. 19, 2006, the 758th Martian day of exploration of the red planet by NASA's Mars Exploration Rover Spirit, the rover acquired this panoramic view of the interior of 'Home Plate,' a circular topographic feature amid the 'Columbia Hills.' This view, called the 'Paige' panorama, is from the top of Home Plate. It shows layered rocks exposed at the edge as well as dark rocks exhibiting both smooth and sponge-like 'scoriaceous' textures. To the east from this vantage point, 'McCool Hill' looms on the horizon. At the base of McCool Hill is a reddish outcrop called 'Oberth,' which Spirit may explore during the rapidly approaching Martian winter. 'Von Braun' and 'Goddard' hills are partially visible beyond the opposite rim of Home Plate.

The limited spatial coverage of this panorama is the result of steadily decreasing power available to the rover for science activities as the Martian winter arrives and the sun traces a lower path across the sky. The rover team anticipates that the north-facing slopes of McCool Hill should sufficiently tilt the rover's solar panels toward the sun to allow Spirit to survive the winter.

The view covers about 230 degrees of terrain around the rover. Spirit's panoramic camera (Pancam) took 72 separate images of this scene with four different Pancam filters. This is a false-color rendering using the Pancam's 75-nanometer, 535-nanometer, and 432-nanometer filters, enhanced to show many subtle color differences in rocks, soils, and hills in the scene. Image-to-image seams have been eliminated from the sky portion of the mosaic to better simulate the vista a person standing on Mars would see.

The Myth of the "Perfect" Child

ERIC Educational Resources Information Center

Werner Andrews, Sarah

2017-01-01

Drawing on both extensive professional and deeply personal experience, Sarah Werner Andrews' vision of working with children carries profound respect and love throughout her guiding insight. She shares an understanding of those children who are the most challenging and provides a framework that allows us to embrace these and all children.…

Spitznävi: unterschiedliche klinische, dermatoskopische und histopathologische Merkmale in der Kindheit.

PubMed

Dika, Emi; Neri, Iria; Fanti, Pier Alessandro; Barisani, Alessia; Ravaioli, Giulia Maria; Patrizi, Annalisa

2017-01-01

Die Charakterisierung der klinischen Merkmale und des biologischen Potenzials von Spitznävi hat in den letzten Jahrzehnten breites Interesse gefunden. Das Ziel dieser Arbeit ist die Beschreibung der klinischen und dermatoskopischen Merkmale von Spitznävi sowie des klinischen Ergebnisses nach chirurgischer Exzision von Spitznävi in drei pädiatrischen Altersgruppen. Restrospektive Studie zur Analyse von klinischen Merkmalen, videodermatoskopischen Bildern, histopathologischen Diagnosen und Behandlungsergebnissen. Der Grad der Pigmentierung wurde sowohl klinisch als auch histopathologisch beurteilt. Bei 71 Patienten wurden 72 spitzoide Neoplasien entfernt. Videodermatologische Bilder lagen für 41 Patienten vor. Das Muster der Pigmentierung korrelierte signifikant mit dem Alter der Patienten: Hyperpigmentierte Läsionen waren bei Vorschulkindern selten, bei Patienten von 7 bis 12 Jahren und ab 13 Jahren dagegen häufiger. Eine histopathologische Diagnose von atypischen Spitznävi wurde selten durchgeführt. Keiner der Patienten, bei denen ursprünglich ein atypischer Spitznävus diagnostiziert worden war, entwickelte ein Lokalrezidiv oder Metastasen während der anschließenden Nachbeobachtung. Pigmentierte Spitznävi traten im Alter ab 13 Jahren häufiger auf. Die Studie bestätigt andere Berichte über die Altersverteilung von Pigmentierungsmustern und hebt die geringe Anzahl atypischer Spitznävi bei pädiatrischen Patienten hervor sowie das Ausbleiben von Rezidiven bei der langfristigen Nachbeobachtung. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Titanisierung von Implantatoberflächen

NASA Astrophysics Data System (ADS)

Zimmermann, Hanngörg; Heinlein, Markus; Guldner, Norbert W.

Titan gilt seit Jahrzehnten als einer der wichtigsten Implantatwerkstoffe in der Medizin. Neben den guten mechanischen Eigenschaften (Leichtigkeit, hohe Festigkeit etc.), besitzen Titanimplantate vor allem eine hervorragende Körperverträglichkeit, so dass die Implantate optimal in den humanen Organismus integriert werden [1]. Ist jedoch aufgrund der Anforderungen an das Implantat eine hohe Flexibilität und/ oder Elastizität gefragt, so scheidet der Werkstoff Titan aufgrund seiner spröden und unflexiblen Materialeigenschaften aus. Die Folge ist der Einsatz von Implantatmaterialien, sowohl künstlichen als auch biologischen Ursprungs, welche nicht selten eine unzureichende Biokompatibilität aufweisen und somit zu Fremdköper- und immunologischen Reaktionen und Einkapselung des Implantates führen können. Die Erhöhung der Körperverträglichkeit, eine Adaption an das biologische Umfeld und eine hohe Biokompatibilität sind demzufolge die wichtigsten Eigenschaften bei der bedarfsgerechten Herstellung von Implantaten und Implantatoberflächen. Zur Gestaltung von innovativen, biokompatiblen Oberflächen stehen unterschiedliche technische Lösungsansätze zur Verfügung. Zum einen besteht die Möglichkeit, geeignete Oberflächeneigenschaften aus dem Grundmaterial selbst zu optimieren. Dies geschieht unter anderem durch Modifikation der Werkstoffoberflächen in Form von Texturierungen und Oberflächenrauhigkeiten. Zum anderen können die Oberflächeneigenschaften unabhängig von denen des Trägermaterials gestaltet werden. Durch Funktionalisierung der Oberflächen mit geeigneten Beschichtungen oder der Zugabe von Medikamenten (Drug Eluting) werden die Kunststoffimplantate dahingehend verändert, dass eine Steigerung der Körperakzeptanz erreicht wird. Die Titanbeschichtung von Implantatoberflächen kombiniert die positiven Materialeigenschaften von Titan und Polymer.

Epidemiologie, Prävention und Früherkennung des Zervixkarzinoms

PubMed Central

Wentzensen, Nicolas

2016-01-01

Zusammenfassung Hintergrund Persistierende Infektionen mit humanen Papillomviren sind die notwendige Ursache des Zervixkarzinoms. Die Entwicklung von HPV-basierten Präventionsverfahren, der HPV Impfung und der HPV-Testung, führt derzeit zu umfangreichen Veränderungen von Zervixkarzinom-Vorsorgeprogrammen. Eine Dekade nach Einführung der HPV-Imfpung in vielen Ländern werden bereits Reduktionen von HPV-Infektionen und Krebsvorstufen in jungen Frauen beobachtet. Der Fokus liegt jetzt auf der Integration von neuen Testverfahren im Screening von Populationen mit zunehmenden Impfraten. Ergebnisse und Schlussfolgerung Ein erfolgreiches Zervixkarzinom-Vorsorgeprogramm besteht aus verschiedenen Komponenten, vom primären Screening über die Triage zur Kolposkopie mit Biopsie, um Frauen mit Kresbvorstufen zu identifizieren, die eine therapeutische Intervention benötigen. Im primären Screening wird eine kleine Gruppe von Frauen mit erhöhtem Risiko für eine Krebsvorstufe identifiziert, während die grosse Mehrheit kein erhöhtes Risiko hat. Je nach primärem Testverfahren werden in screen-positiven Frauen zusätzliche Triage-Tests durchgeführt, um zu entscheiden, wer zur Kolposkopie überwiesen werden sollte. Derzeit gibt es drei verschiedene Ansätze für das primäre Zervixkarzinomscreening: Die Zervix-Zytologie, die HPV-Testung, und die HPV-Zytologie Ko-Testung. Zahlreiche Triage-Tests für HPV-positive Frauen werden derzeit untersucht, darunter sind die Zytologie, HPV-Genotypisierung, p16/Ki-67 Zytologie, und diverse Methylierungstests. Die steigende Anzahl an Optionen für die Früherkennung des Zervixkarzinoms stellt eine Herausforderung für klinische Leitlinien dar. Die zunehmende Komplexität von Vorsorgeprogrammen kann zur Verunsicherung von Ärzten und von am Screening teilnehmenden Frauen führen. Die Präzisions-Prävention des Zervixkarzinoms ist eine neuer Ansatz, der umfangreiche Risikodaten basierend auf der individuellen Vorgeschichte und von Testergebnissen integriert und einheitliche, Risiko-basierte Managementempfehlungen gibt. PMID:28265177

Alexander von Humboldt and the concept of animal electricity.

PubMed

Kettenmann, H

1997-06-01

More than two hundred years ago, Alexander von Humboldt helped to establish Galvani's view that muscle and nerve tissue are electrically excitable. His 1797 publication was a landmark for establishing the concept of animal electricity. Almost half a century later, von Humboldt became the mentor of the young du Bois-Reymond. With the help of von Humboldt's promotion, du Bois-Reymond demonstrated convincingly that animal tissue has the intrinsic capacity to generate electrical activity, and thus laid the ground for modern electrophysiology.

Effects on the pouch of different digestive tract reconstruction modes assessed by radionuclide scintigraphy

PubMed Central

Li, Dong-Sheng; Xu, Hui-Mian; Han, Chun-Qi; Li, Ya-Ming

2010-01-01

AIM: To determine the effect of three digestive tract reconstruction procedures on pouch function, after radical surgery undertaken because of gastric cancer, as assessed by radionuclide dynamic imaging. METHODS: As a measure of the reservoir function, with a designed diet containing technetium-99m (99mTc), the emptying time of the gastric substitute was evaluated using a 99mTc-labeled solid test meal. Immediately after the meal, the patient was placed in front of a γ camera in a supine position and the radioactivity was measured over the whole abdomen every minute. A frame image was obtained. The emptying sequences were recorded by the microprocessor and then stored on a computer disk. According to a computer processing system, the half-emptying actual curve and the fitting curve of food containing isotope in the detected region were depicted, and the half-emptying actual curves of the three reconstruction procedures were directly compared. RESULTS: Of the three reconstruction procedures, the half-emptying time of food containing isotope in the Dual Braun type esophagojejunal anastomosis procedure (51.86 ± 6.43 min) was far closer to normal, significantly better than that of the proximal gastrectomy orthotopic reconstruction (30.07 ± 15.77 min, P = 0.002) and P type esophagojejunal anastomosis (27.88 ± 6.07 min, P = 0.001) methods. The half-emptying actual curve and fitting curves for the Dual Braun type esophagojejunal anastomosis were fairly similar while those of the proximal gastrectomy orthotopic reconstruction and P type esophagojejunal anastomosis were obviously separated, which indicated bad food conservation in the reconstructed pouches. CONCLUSION: Dual Braun type esophagojejunal anastomosis is the most useful of the three procedures for improving food accommodation in patients with a pouch and can retard evacuation of solid food from the reconstructed pouch. PMID:20238408

Risk, Resilience, and Recovery

ERIC Educational Resources Information Center

Werner, Emmy

2012-01-01

In 1955, the first longitudinal study of resilience began on the island of Kauai. This research continues to the present. This article presents an interview with Emmy Werner, the principal investigator. In a series of five books published over a period of thirty years, she demonstrated the remarkable ability of children from difficult backgrounds…

Vortex wakes of a flapping foil in a flowing soap film

NASA Astrophysics Data System (ADS)

Schnipper, Teis; Andersen, Anders; Bohr, Tomas

2008-11-01

We present an experimental study of an oscillating, symmetric foil in a vertically flowing soap film. By varying frequency and amplitude of the oscillation we explore and visualize a variety of wake structures, including von Kármán wake, reverse von Kármán wake, 2P wake, and 2P+2S wake. We characterize the transition from the von Kármán wake (drag) to the reverse von Kármán wake (thrust) and discuss the results in relation to fish swimming. We visualize the time evolution of the vortex shedding in detail, identify the origins of the vortices comprising the wake, and propose a simple model to account for the transition from von Kármán like wakes to more exotic wake structures.

Trends in Modern War Gaming: The Art of Conversation

DTIC Science & Technology

2014-01-01

overtook, and in some cases replaced, these thought processes. as Jung aptly noted, “in the West, consciousness has been developed mainly through...Werner Heisenberg’s uncertainty principle in 1927, successive generations of quantum theorists have moved well beyond anecdotal claims into the realm of

Herlyn-Werner-Wunderlich syndrome (uterus didelphys, blind hemivagina and ipsilateral renal agenesis) - a case report

PubMed Central

Arıkan, İlker İnan; Harma, Müge; Harma, Mehmet İbrahim; Bayar, Ülkü; Barut, Aykut

2010-01-01

Uterovaginal duplication with obstructed hemivagina and ipsilateral renal agenesis is referred to as the Herlyn-Werner-Wunderlich (HWW) syndrome. A 17 year old woman presented with right pelvic pain and dysmenorrhea, present since menarche at 13 and worsening over the past year. Ultrasound examination revealed a right pelvic mass (5×5 cm), double endometrial echoes, and hematocolpos. A right pelvic mass, agenesis of the right kidney, double uterus, and blind hemivagina with hematocolpos were detected by magnetic resonance imaging and intravenous pyelography. A right tubo-ovarian abscess with dense adhesions and a double uterus were observed on diagnostic laparoscopy. Adhesiolysis was carried out and purulent material irrigated. After a course of antibiotics, a vaginal septum resection was performed and the pyocolpos drained. She remained symptom free after four months of follow-up. Prompt and accurate diagnosis and treatment of this syndrome can significantly improve the lives of sufferers and prevent future complications. PMID:24591910

A Brief Review of Some Approaches to Hysteresis in Viscoelastic Polymers

DTIC Science & Technology

2008-01-27

Pokrovskii, Systems with Hysteresis, Nauka, Moscow, 1983; translated, Springer-Verlag, Berlin, 1989. [46] V. Lakshmikantham and M. Rama Mohana Rao ...S.G. Braun, D. Ewins and S. Rao , eds.), Academic Press, London, 2001, 658–664. [23] H.T. Banks and G.A. Pinter, A probabilistic multiscale approach

Response of different common bean lines to Phaeoisariopsis griseola in Puerto Rico

USDA-ARS?s Scientific Manuscript database

Angular leaf spot (ALS), caused by Phaeoisariopsis griseola (Sacc.) Ferraris sin. Pseudocercospora griseola (Sacc.) Crous & U. Braun., is an important disease in common bean Phaseolus vulgaris L. in the Caribbean and Central America. The wide pathogen variability makes it necessary to continuously m...

von Baer's law for the ages: lost and found principles of developmental evolution.

PubMed

Abzhanov, Arhat

2013-12-01

In 1828, Karl Ernst von Baer formulated a series of empirically defined rules, which became widely known as the 'Law of Development' or 'von Baer's law of embryology'. This was one the most significant attempts to define the principles that connected morphological complexity and embryonic development. Understanding this relation is central to both evolutionary biology and developmental genetics. Von Baer's ideas have been both a source of inspiration to generations of biologists and a target of continuous criticism over many years. With advances in multiple fields, including paleontology, cladistics, phylogenetics, genomics, and cell and developmental biology, it is now possible to examine carefully the significance of von Baer's law and its predictions. In this review, I argue that, 185 years after von Baer's law was first formulated, its main concepts after proper refurbishing remain surprisingly relevant in revealing the fundamentals of the evolution-development connection, and suggest that their explanation should become the focus of renewed research. Copyright © 2013 Elsevier Ltd. All rights reserved.

The Influence of Field Marshal Colmar Von Der Goltz on Ottoman Military Effectiveness in Mesopotamia: December 1915 to April 1916

DTIC Science & Technology

2012-02-23

SUBTITLE The Influence of Field Marshal Colmar Von Der Goltz on Ottoman Military Effectiveness in Mesopotamia: December 1915 to April 1916 5a...SUPPLEMENTARY NOTES N/A 14. ABSTRACT This paper discusses the contributions made by Field Marshal Colmar von der Goltz on the development of Ottoman...Kut. 15. SUBJECT TERMS Colmar von der Goltz ; Military advisor; Mesopotamian Campaign; Ottoman; Ottoman military effectiveness; British; Kut; World

Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor

PubMed Central

Bierings, Ruben; Meems, Henriet; Mul, Frederik P. J.; Geerts, Dirk; Vlaar, Alexander P. J.; Voorberg, Jan; Hordijk, Peter L.

2017-01-01

Adhesion of erythrocytes to endothelial cells lining the vascular wall can cause vaso-occlusive events that impair blood flow which in turn may result in ischemia and tissue damage. Adhesion of erythrocytes to vascular endothelial cells has been described in multiple hemolytic disorders, especially in sickle cell disease, but the adhesion of normal erythrocytes to endothelial cells has hardly been described. It was shown that calcium-loaded erythrocytes can adhere to endothelial cells. Because sickle erythrocyte adhesion to ECs can be enhanced by ultra-large von Willebrand factor multimers, we investigated whether calcium loading of erythrocytes could promote binding to endothelial cells via ultra-large von Willebrand factor multimers. We used (immunofluorescent) live-cell imaging of washed erythrocytes perfused over primary endothelial cells at venular flow rate. Using this approach, we show that calcium-loaded erythrocytes strongly adhere to histamine-stimulated primary human endothelial cells. This adhesion is mediated by ultra-large von Willebrand factor multimers. Von Willebrand factor knockdown or ADAMTS13 cleavage abolished the binding of erythrocytes to activated endothelial cells under flow. Platelet depletion did not interfere with erythrocyte binding to von Willebrand factor. Our results reveal platelet-independent adhesion of calcium-loaded erythrocytes to endothelium-derived von Willebrand factor. Erythrocyte adhesion to von Willebrand factor may be particularly relevant for venous thrombosis, which is characterized by the formation of erythrocyte-rich thrombi. PMID:28249049

Analyse der pharmazeutischen Versorgungssituation von Patienten mit Psoriasis-Arthritis auf Basis von Routinedaten der Gesetzlichen Krankenversicherung.

PubMed

Sondermann, Wiebke; Ventzke, Julia; Matusiewicz, David; Körber, Andreas

2018-03-01

Die Psoriasis-Arthritis (PsA) gehört zu den chronisch entzündlichen Gelenkerkrankungen. Trotz zahlreicher versorgungswissenschaftlicher Studien in Deutschland liegen zur pharmazeutischen Versorgungssituation von PsA-Patienten bisher kaum aktuelle Ergebnisse vor. Mit Hilfe einer systematischen Literaturrecherche sowie anhand von Routinedaten der Allgemeinen Ortskrankenkasse (AOK) Rheinland/Hamburg wird ein aktueller Überblick über die pharmazeutische Versorgung von PsA-Patienten in Deutschland gegeben. Selektiert wurden Versicherte aus dem ambulanten und stationären Bereich, die im 1. und 2. Quartal des Jahres 2014 die gesicherte Abrechnungsdiagnose Psoriasis-Arthritis L40.5+ aufwiesen. Anschließend wurden auf Basis dieser "vorab definierten" Kohorte die Arzneimitteldaten für 5 Jahre (01.01.2010-31.12.2014) abgerufen. Es konnten insgesamt n  =  3205 Versicherte (45 % männlich, 55 % weiblich) der AOK Rheinland/Hamburg mit einer gesicherten PsA-Diagnose selektiert werden. Das Durchschnittsalter betrug 58,9 Jahre. 53,7 % der PsA-Patienten wurden mit systemischen PsA-relevanten Arzneimitteln versorgt. Nichtsteroidale Antirheumatika (NSAR) wurden am häufigsten verordnet, gefolgt von systemischen Glucocorticoiden. Von den selektierten PsA-Patienten, die eine Systemtherapie erhielten, wurden 72,1 % mittels einer Disease-modifying-antirheumatic-Drug (DMARD)-Monotherapie behandelt, gefolgt von der Kombinationstherapie aus DMARDs und Biologika (20,9 %). Die pharmakologische Therapie der PsA muss eine Gewährleistung zwischen adäquater Versorgung der PsA mit Verhinderung der Krankheitsprogression und ökonomischer Verantwortung darstellen. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Rediscovery of Atelopus subornatus Werner, 1899 (Anura: Bufonidae), with a redescription of the tadpole.

PubMed

Enciso-Calle, Maria Paula; Viuche-Lozano, Andres; Anganoy-Criollo, Marvin; Bernal, Manuel Hernando

2017-11-06

The Neotropical toads of the genus Atelopus are among the most imperiled of all amphibians (La Marca et al. 2005; Gonzalez-Maya et al. 2013; McCaffery et al. 2015). Nowadays, at least 90% of the 93 listed species are threatened and more than 77% are Critically Endangered (McCaffery et al. 2015; IUCN 2016). Colombia has 44 described species of Atelopus (Frost 2017), two of these are categorized as extinct (EX) by the IUCN (2016): A. ignescens and A. longirostris, although they were recently re-discovered in Ecuador (Tapia et al. 2017), 34 as critical endangered (CR), four as endangered (EN), two as vulnerable (VU), one species has data deficient (DD) and another one has not been evaluated. Atelopus subornatus Werner, 1899, is an endemic Colombian harlequin toad described from 2300 to 2800 m.a.s.l in the municipalities of Sibaté (Alto de Sibaté and Agua Bonita) and Fusagasuga (above Fusagasuga and Tierra Negra), in Cundinamarca (Fig. 1A), on the western flank from Cordillera Oriental of Colombia (Werner 1899; Lynch 1986; Lötters 1989, 1992). The last record of this species was in 1993 (Lötters 2005), and it currently is listed as Critically Endangered by the IUCN (2016). Herein, we report the rediscovery of A. subornatus at a new locality from Tolima, Colombia (Fig. 1A), and redescribe its tadpole. The determination of the species was based on comparisons with material deposited in the amphibian collection of the Instituto de Ciencias Naturales, Universidad Nacional de Colombia (ICN-UNAL) for all species of Atelopus reported from the same general area in Cundinamarca and relatively similar to A. subornatus. The specimens are housed in the Herpetological collection of the Tolima University (CZUT-A) and amphibian collection of ICN-UNAL.

Perceptions of Adult Males Who Participated in Counseling for Trauma: A Generic Qualitative Study

ERIC Educational Resources Information Center

Pullen, Annette M.

2017-01-01

This generic qualitative inquiry explored the perceptions of adult males regarding their counseling for trauma experiences. Through that exploration, literature was enhanced considering the information processing theory. Individual interviews of 10 men were conducted using semi-structured, open-ended questions. Braun and Clarke's thematic analysis…

Reaction of the BASE 120 lines to angular leaf spot in Puerto Rico

USDA-ARS?s Scientific Manuscript database

Common bean (Phaseolus vulgaris L.) is limited by diseases such as Angular leaf spot (ALS), caused by Phaeoisariopsis griseola (Sacc.) Ferraris sin. Pseudocercospora griseola (Sacc.) Crous & U. Braun. The virulence of Phaeoisariopis griseola isolate ALS-9029-JD2 from Juana Diaz, PR was determined by...

Metallosupramolecular Architectures Obtained from Poly-N-heterocyclic Carbene Ligands.

PubMed

Sinha, Narayan; Hahn, F Ekkehardt

2017-09-19

Over the past two decades, self-assembly of supramolecular architectures has become a field of intensive research due to the wide range of applications for the resulting assemblies in various fields such as molecular encapsulation, supramolecular catalysis, drug delivery, metallopharmaceuticals, chemical and photochemical sensing, and light-emitting materials. For these purposes, a large number of coordination-driven metallacycles and metallacages featuring different sizes and shapes have been prepared and investigated. Almost all of these are Werner-type coordination compounds where metal centers are coordinated by nitrogen and/or oxygen donors of polydentate ligands. With the evolving interest in the coordination chemistry of N-heterocyclic carbenes (NHCs), discrete supramolecular complexes held together by M-C NHC bonds have recently become of interest. The construction of such metallosupramolecular assemblies requires the synthesis of suitable poly-NHC ligands where the NHC donors form labile bonds with metal centers thus enabling the formation of the thermodynamically most stable reaction product. In organometallic chemistry, these conditions are uniquely met by the combination of poly-NHCs and silver(I) ions where the resulting assemblies also offer the possibility to generate new structures by transmetalation of the poly-NHC ligands to additional metal centers forming more stable C NHC -M bonds. Stable metallosupramolecular assemblies obtained from poly-NHC ligands feature special properties such as good solubility in many less polar organic solvents and the presence of the often catalyticlly active {M(NHC) n } moiety as building block. In this Account, we review recent developments in organometallic supramolecular architectures derived from poly-NHC ligands. We describe dinuclear (M = Ag I , Au I , Cu I ) tetracarbene complexes obtained from bis-NHC ligands with an internal olefin or two external coumarin pendants and their postsynthetic modification via a photochemically induced single or double [2 + 2] cycloaddition to form dinuclear tetracarbene complexes featuring cyclobutane units. Even three-dimensional cage-like structures can be prepared by this postsynthetic strategy. Cylinder-like trinuclear, tetranuclear, and hexanuclear (M = Ag I , Au I , Cu I , Hg II , Pd II ) complexes have been obtained from benzene-bridged tris-, tetrakis-, or hexakis-NHC ligands. These complexes resemble polynuclear assemblies obtained from related polydentate Werner-type ligands. Contrary to the Werner-type complexes, cylinder-like assemblies with three, four, or six silver(I) ions sandwiched in between two tris-, tetrakis-, or hexakis-NHC ligands undergo a facile transmetalation reaction to give the complexes featuring more stable M-C NHC bonds, normally with retention of the metallosupramolecular structure. This unique behavior of NHC-Ag + complexes allows the prepration of assemblies containing various metals from the poly-NHC silver(I) assemblies. Narcissistic self-sorting phenomena have also been observed for mixtures of selected poly-NHC ligands and silver(I) ions. Even a very early type of metallosupramolecular assembly, the tetranuclear molecular square, can be prepared from four bridging dicarbene ligands and four transition metal ions either by a stepwise assembly or by a single-step protocol. At this point, it appears that procedures for the synthesis of metallosupramolecular assemblies using polydentate Werner-type ligands and metal ions can be transferred to organometallic chemistry by using suitable poly-NHC ligands. The resulting structures feature stable M-C NHC bonds (with the exception of the labile C NHC -Ag + bond) when compared to M-N/M-O bonds in classical Werner-type complexes. The generally good solubility of the compounds and the presence of the often catalytically active {M(NHC) n } moiety make organometallic supramolecular complexes a promising new class of molecular hosts for catalytic transformations and encapsulation of selected substrates.

Unusual bridging of three nitrates with two bridgehead protons in an octaprotonated azacryptand

PubMed Central

Saeed, Musabbir A.; Fronczek, Frank R.; Huang, Ming-Ju; Hossain, Md. Alamgir

2010-01-01

Structural analysis of the nitrate complex of a thiophene-based azacryptand suggests that three nitrates are bridged with two bridgehead protons which play the topological role of two transition metal ions in a classical Werner type coordination complex bridging three anions. PMID:20066306

The Role of Idiomorphs in Emergent Literacy

ERIC Educational Resources Information Center

Neumann, Michelle M.; Neumann, David L.

2012-01-01

Psycholinguistics coined the term idiomorph to describe idiosyncratic invented word-like units that toddlers use to refer to familiar objects during their early language development (Haslett & Samter, 1997; Otto, 2008; Reich, 1986; Scovel, 2004; Werner & Kaplan, 1963). Idiomorphs act as "words" because their meanings and phonetic pronunciations…

Where Are They Now: Former WHK Intern Julianne Heberlein Moves from Science to Politics | Poster

Cancer.gov

Former Werner H. Kirsten (WHK) intern Julianne Heberlein—who worked in the Frederick National Laboratory Public Affairs and Communication Office under Frank Blanchard—credits the WHK program with setting her apart from other applicants when applying for her recent internships.

"Paideia," Then and Now.

ERIC Educational Resources Information Center

Keppel, Francis

1990-01-01

Discusses two widely practiced principles of management (protecting the rear and knowing the limits of a job) as they relate to the philosophy of education. The article examines Werner Jaeger's definition of education in his 1939 book, "Paideia," as well as other definitions that have helped shape current educational management. (SM)

Good scientists and honest people

NASA Astrophysics Data System (ADS)

Robinson, Andrew

2014-06-01

In early 1948, less than three years after the end of the Second World War in Europe, Werner Heisenberg - the Nobel laureate and physicist leader of the failed German atomic bomb project - was invited to the UK as part of an attempt to repair relations between British and German physicists.

U.S. Teachers as Policy Protagonists in Digital Public Spaces?

ERIC Educational Resources Information Center

Robert, Sarah A.

2017-01-01

Teachers engage with policies far beyond the confines of their classroom and seemingly unrelated to their classroom practice, stretching the parameters of theories such as street-level bureaucracy (Lipsky, 2010; Weatherly & Lipsky, 1977) and doing policy in schools (Ball, Maguire, & Braun, 2012). This was observed in ethnographic studies…

Teacher Inquiry from Knowledge to Knowledges

ERIC Educational Resources Information Center

Kiss, Katherine L.; Townsend, Jane S.

2012-01-01

The literature indicates that teacher educators have a responsibility to prepare new teachers philosophically and practically as reflective "researchers" who are in the habit of systematic, active, and goal-directed problem-posing and are attentive to the processes in which they are immersed (Braun & Crumpler, 2004; Cochran-Smith-Lytle, 1999;…

The historical development of modern virus research in Germany, especially in the Kaiser-Wilhelm-/Max-Planck-Society, 1936--1954.

PubMed

Butenandt, A

1977-01-01

This is lecture on the historical development of modern virus research in Germany to introduce a symposium dedicated to Prof. Werner Schäfer, Tübingen, on the occasion of his 65th birthday. The author was set the task of relating from his memories the beginning of modern virus research in Germany. This research has, since 1936, essentially taken place in the Kaiser-Wilhelm/Max-Planck-Society and in 1954 led to the founding of the Max-Planck-Institute for Virus Research in Tübingen, an institute which to the present day owes its scientific reputation in considerable part to the activity of Werner Schäfer. Since the author personally experienced and participated in the Institute's development from 1936-1954, his remarks are predominantly influenced by personal recollections, which have been sharpended by a renewed study of old records in the 'Library and Archive of the History of the Max-Planck-Gesellschaft', Berlin-Dahlem.

Martha Muchow, 1892-1933: Her Life, Work, and Contribution to Developmental and Ecological Psychology.

ERIC Educational Resources Information Center

Wohlwill, Joachim F.

1985-01-01

Introduces the 1983 SRCD symposium on Martha Muchow, the German child psychologist and associate of William Stern and Heinz Werner at the University of Hamburg. Her work integrates developmental and ecological approaches to the study of children's knowledge of and interaction with their physical surroundings. (Author/SO)

The Physics of "Copenhagen" for Students and the General Public.

ERIC Educational Resources Information Center

Bergstrom, L.; Johansson, K. E.; Nilsson, Ch.

2001-01-01

The play Copenhagen has attracted the attention of a large audience in several countries. The hypothetical discussion between two of the giants in physics, Niels Bohr and Werner Heisenberg, has inspired us to start a theoretical and experimental exploration of quantum physics. This theme has been used in Stockholm Science Laboratory for audiences…

Twin-Screw Extruders in Ceramic Extrusion

NASA Astrophysics Data System (ADS)

Wiedmann, Werner; Hölzel, Maria

The machines mainly used for compounding plastics, chemicals and food are co-rotating, closely intermeshing twin-screw extruders. Some 30 000 such extruders are in use worldwide, about 1/3 are ZSKs from Coperion Werner & Pfleiderer, Stuttgart. In the chemical industry more and more batch mixers are being replaced by continuous twin-screw kneaders.

Netz ohne doppelten Boden: Internet-Sicherheit

NASA Astrophysics Data System (ADS)

Fichtner, Johann

2002-07-01

Die Sicherheitslücken des heutigen Internets haben zwei Ursachen: sein ursprüngliches Design für rein militärische Zwecke sowie die gefährliche Sorglosigkeit der Entwickler und Betreiber von Internet-Komponenten. Dabei kann ein kleiner Kreis von Experten Angriffe auf die eigentlichen Netzknoten ausführen. Typische Hacker-Angriffe kommen von Endsystemen des Internets und richten sich auch gegen Endsysteme wie Firmen-Intranets oder einzelne PCs. Dagegen gibt es eine Reihe von Schutzmöglichkeiten. Es ist jedoch keine einfache Lösung zur Erhöhung der Internet-Sicherheit in Sicht.

Design Review Improvements Product Overview

DTIC Science & Technology

2015-05-07

Boeing Anne Ramsey, Harris Corporation Ronald H. Mandel, Lockheed Martin Mark King, Micropac Industries Melanie Berg, NASA Cindy Kohlmiller...Northrop Grumman craig.wesser@ngc.com Richard Fink NRO finkrich@nro.mil Marvin LeBlanc NOAA Marvin.LeBlanc@noaa.gov Robert Adkisson Boeing...Dennis.Boiter@intelsatgeneral.com Silva Bouchard Northrop Grumman Silvia.Bouchard@ngc.com Mark Braun Raytheon mark.j.braun@raytheon.com Marvin Candee

New Sources of Resistance to Cucurbit Powdery Mildew in Melon

USDA-ARS?s Scientific Manuscript database

Many physiological races of the cucurbit powdery mildew pathogen (CPM) Podosphaera xanthii (Castagne) Braun & Shishkoff have been reported on melon (Cucumis melo L.). Melon accession PI 313970 is the only reported source of host plant resistance to race S, which first appeared in Imperial Valley, CA...

Einsatz molekularer Methoden für Starterkulturen

NASA Astrophysics Data System (ADS)

Ehrmann, Matthias A.; Pavlovic, Melanie

Unter Starterkulturen versteht man Mikroorganismen (Bakterien, Hefen, Pilze), die pflanzlichen bzw. tierischen Rohstoffen zur gezielten Veränderung ihrer chemischen Zusammensetzung zugesetzt werden. Sie dienen im Wesentlichen der Aromabildung, der Strukturveränderung und der Konservierung der Lebensmittel und werden aufgrund spezieller, funktioneller Eigenschaften selektiert. Die Zugabe von Starterkulturen erfolgt in der Regel in relativ hohen Keimzahlen in Form von Rein- oder Mischkulturen. Die zum Einsatz kommenden Mikroorganismen sind ebenso zahlreich wie die daraus resultierenden Produkte und reichen von der Fermentation von Milchprodukten, Fleisch und Gemüse durch Milchsäurebakterien über die Essigsäureherstellung bis hin zum Einsatz von Hefen in der Brau- und Weinindustrie. Hieraus ergibt sich auch eine zunehmende Bedeutung schneller und zuverlässiger Methoden zur taxonomischen Identifizierung, aber auch zur Charakterisierung des genetischen Potenzials der jeweiligen Starterkulturen.

New species of Anisophya Karabag from Chile (Orthoptera: Tettigoniidae: Phanopterinae)

USDA-ARS?s Scientific Manuscript database

Many of the most primitive Neotropical bush katydids (Phaneropterinae) — including species of Cosmophyllum Blanchard, Stenophylla Brunner von Wattenwyl, Marenestha Brunner von Wattenwyl, Anisophya Karabag, Coryphoda Brunner von Wattenwyl, and Burgilis Stål — are endemic in Chile. The Chilean species...

Von Neumann was not a Quantum Bayesian.

PubMed

Stacey, Blake C

2016-05-28

Wikipedia has claimed for over 3 years now that John von Neumann was the 'first quantum Bayesian'. In context, this reads as stating that von Neumann inaugurated QBism, the approach to quantum theory promoted by Fuchs, Mermin and Schack. This essay explores how such a claim is, historically speaking, unsupported. © 2016 The Author(s).

Test of Von Baer's law of the conservation of early development.

PubMed

Poe, Steven

2006-11-01

One of the oldest and most pervasive ideas in comparative embryology is the perceived evolutionary conservation of early ontogeny relative to late ontogeny. Karl Von Baer first noted the similarity of early ontogeny across taxa, and Ernst Haeckel and Charles Darwin gave evolutionary interpretation to this phenomenon. In spite of a resurgence of interest in comparative embryology and the development of mechanistic explanations for Von Baer's law, the pattern itself has been largely untested. Here, I use statistical phylogenetic approaches to show that Von Baer's law is an unnecessarily complex explanation of the patterns of ontogenetic timing in several clades of vertebrates. Von Baer's law suggests a positive correlation between ontogenetic time and amount of evolutionary change. I compare ranked position in ontogeny to frequency of evolutionary change in rank for developmental events and find that these measures are not correlated, thus failing to support Von Baer's model. An alternative model that postulates that small changes in ontogenetic rank are evolutionarily easier than large changes is tentatively supported.

Voices for Diversity.

ERIC Educational Resources Information Center

Future Teacher, 1995

1995-01-01

Prominent Americans were asked to reflect on the diversity challenge facing America's teacher workforce. The following leaders from several fields voiced their support of teachers and their beliefs America needs more diverse and culturally responsive teachers: (1) Mary Hatwood Futrell, President of Education International; (2) Carol Moseley-Braun,…

The "Hard Problem" and the Quantum Physicists. Part 1: The First Generation

ERIC Educational Resources Information Center

Smith, C. U. M.

2006-01-01

All four of the most important figures in the early twentieth-century development of quantum physics--Niels Bohr, Erwin Schroedinger, Werner Heisenberg and Wolfgang Pauli--had strong interests in the traditional mind--brain, or "hard," problem. This paper reviews their approach to this problem, showing the influence of Bohr's complementarity…

WHK Interns Win Big at Frederick County Science Fair | Poster

Cancer.gov

Three Werner H. Kirsten student interns claimed awards at the 35th Annual Frederick County Science and Engineering Fair—and got a shot at the national competition—for imaginative projects that reached out to the rings of Saturn and down to the details of advanced cancer diagnostics.

How Great Is Your Student Intern? | Poster

Cancer.gov

Editor’s note: We asked Werner H. Kirsten Student Internship Program (WHK SIP) mentors to tell us about the unique and diverse backgrounds of some of this year’s student interns. Alex Beall Microarray Group, Genomics Laboratory, Cancer Research Technology Program Mentors: Nicole Shrader and Stephanie Mellott, research associates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giovannetti, Vittorio; Lloyd, Seth; Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139

The Amosov-Holevo-Werner conjecture implies the additivity of the minimum Renyi entropies at the output of a channel. The conjecture is proven true for all Renyi entropies of integer order greater than two in a class of Gaussian bosonic channel where the input signal is randomly displaced or where it is coupled linearly to an external environment.

A Developmental Framework for Enhancing Resiliency in Adult Survivors of Childhood Abuse

ERIC Educational Resources Information Center

Orbke, Samantha; Smith, Heather L.

2013-01-01

Roughly one third of children subjected to abusive environments grow into healthy and capable adults, demonstrating remarkable resiliency, despite risks for developing maladaptive self-structures and destructive behaviors (Werner, "American Journal of Orthopsychiatry" 59:72-81 1989; Kendall-Tackett "et al.", "Psychological Bulletin" 113:164-180…

Cul-de-Sac Kids

ERIC Educational Resources Information Center

Hochschild, Thomas R., Jr.

2013-01-01

Previous research indicates that adults who live on cul-de-sac streets are more likely to have positive experiences with neighbors than residents of other street types (Brown and Werner, 1985; Hochschild Jr, 2011; Mayo Jr, 1979; Willmott, 1963). The present research ascertains whether street design has an impact on children's neighborhood…

World Perspective Case Descriptions on Educational Programs for Adults: Federal Republic of Germany.

ERIC Educational Resources Information Center

Bugl, Helmut; And Others

This document contains the following case studies of West German adult education projects: (1) Counseling Courses in Agriculture (Bugl, Fehrenbach-Neumann); (2) The State Center for Political Education in Baden-Wurttemberg (Schiele); (3) Catholic Educational Organization Rottweil (Muller); (4) Adult Education Center--Herrenberg (Werner); (5)…

Windkraftanlagen

NASA Astrophysics Data System (ADS)

Surek, Dominik

Windturbinenanlagen nutzen die kinetische Energie des Windes bei Geschwindigkeiten von c=4 m/s bis 25 m/s in Nabenhöhe des Windrades zur Stromerzeugung. Die oben genannten Windgeschwindigkeiten liegen im Grenzschichtbereich der ebenen Strömung (Abb. 67.1), die bei Höhen von h=100 m bis 1000 m liegen und in Großstädten mit Skylines bis 2000 m. Die größten Windturbinentürme erreichen gegenwärtig Nabenhöhen von h=160 m und Windraddurchmesser von d=130 m, d. h. mit Flügellängen von L=65 m. Die Windturbinen werden vorrangig mit 3 Schaufeln ausgeführt. Windturbinen mit einer und zwei Schaufeln waren Versuchsgeräte. Die Drehzahl von Windturbinen für Leistungen von P_{T}=2 MW betragen n=12 bis 20 min{}^{-1}. Das Windrad entzieht dem Wind mit der Anströmgeschwindigkeit c 1 nach Betz die Geschwindigkeitsdifferenz c2=(2/3) c1. Der Rest der Windgeschwindigkeit wird für die Abströmung des Windes im Leebereich c3=c1/3 benötigt. Durch den Entzug der Geschwindigkeit im Laufrad bläht sich der Abströmdurchmesser auf d3> d1 auf, der bei der Installation von Windturbinen zu beachten ist (Abb. 67.2) [Gasch und Twele(2013)]. Um die Windturbinen bei starkem Wind von c {}1> 25 m/s zu schützen, werden die Laufschaufeln durch Pitch- oder Stall-Anlagen aus dem Wind gedreht, so dass die Strömung an den Schaufeln abreißt und das Windrad in die Ruhestellung gelangt. Bei der Windgeschwindigkeit c1=25 m/s bis 34 m/s wird der Windrotor abgeschaltet. Die zulässige Maximalgeschwindigkeit liegt aus Festigkeitsgründen etwa bei . Die aktive Blattverdrehung (Pitchregelung) stellt eine Blattwinkelregelung dar, wobei die Profilnase in die Anströmung gedreht wird. Sie benötigen für die Drehzahlreduzierung keine mechanische Bremse.

Von Neumann's impossibility proof: Mathematics in the service of rhetorics

NASA Astrophysics Data System (ADS)

Dieks, Dennis

2017-11-01

According to what has become a standard history of quantum mechanics, in 1932 von Neumann persuaded the physics community that hidden variables are impossible as a matter of principle, after which leading proponents of the Copenhagen interpretation put the situation to good use by arguing that the completeness of quantum mechanics was undeniable. This state of affairs lasted, so the story continues, until Bell in 1966 exposed von Neumann's proof as obviously wrong. The realization that von Neumann's proof was fallacious then rehabilitated hidden variables and made serious foundational research possible again. It is often added in recent accounts that von Neumann's error had been spotted almost immediately by Grete Hermann, but that her discovery was of no effect due to the dominant Copenhagen Zeitgeist. We shall attempt to tell a story that is more historically accurate and less ideologically charged. Most importantly, von Neumann never claimed to have shown the impossibility of hidden variables tout court, but argued that hidden-variable theories must possess a structure that deviates fundamentally from that of quantum mechanics. Both Hermann and Bell appear to have missed this point; moreover, both raised unjustified technical objections to the proof. Von Neumann's argument was basically that hidden-variables schemes must violate the ;quantum principle; that physical quantities are to be represented by operators in a Hilbert space. As a consequence, hidden-variables schemes, though possible in principle, necessarily exhibit a certain kind of contextuality. As we shall illustrate, early reactions to Bohm's theory are in agreement with this account. Leading physicists pointed out that Bohm's theory has the strange feature that pre-existing particle properties do not generally reveal themselves in measurements, in accordance with von Neumann's result. They did not conclude that the ;impossible was done; and that von Neumann had been shown wrong.

Velocities and rotational excitation of interstellar H2 toward Pi Scorpii

NASA Technical Reports Server (NTRS)

Jenkins, Edward B.; Lees, Joanna F.; Van Dishoeck, Ewine F.; Wilcots, Eric M.

1989-01-01

A spectrum of Pi Sco showing numerous atomic lines and 70 absorption features from the Lyman and Werner transitions of interstellar H2 in rotational level J from zero to five is presented. Their shapes of the composite column density profiles are very nearly Gaussian with a one-dimensional rms velocity dispersion of 3 km/s. The behavior of shifts in the inferred N(H2) as a function of velocity are consistent with the overall profiles being composed of nearly symmetrical, tightly paced assemblies of about seven unresolved components. The relative overall column densities in the higher J levels of H2 are consistent with a model where these states are populated by optical pumping through the Lyman and Werner transitions, powered by UV radiation from nearby stars. The slight narrowing of the high-J profiles may be due to small clumps of H2 at radial velocities some 5-8 km/s from the core of the profile are exposed to a pumping flux about 10 times lower than that for the material near the profile's center.

Hazardous Waste Cleanup: Von Roll Isola USA Incorporated in Schenectady, New York

EPA Pesticide Factsheets

The Riverview facility is a 52-acre manufacturing facility located on Von Roll Drive in Schenectady, New York. The facility is owned and operated by Von Roll Isola USA, Inc., and produces solid and liquid insulating materials and tapes for the electrical

The Magic Background of Pearl Harbor. Volume 2 (May 12, 1941 - August 6, 1941)

DTIC Science & Technology

1977-01-01

sistance in an Axis move against India.617 German Ambassador Franz von Papen and Foreign Minister Shukru Saracoglu signed a Turkish-German Pact...sadorB rlinportedTokyonJu7,941thatitw sthpinion of Chancellor Hitler and Foreign Minister von Ribbentrop that the United States would hesi...particularlyinregardtowaragainstEngland,HerrHessmighthavebeenanxioustoleaveGermany.ItwasalsoknownthathepossessedagreatdislikeforForeignMin- ister von

[Albert Reder Ritter von Schellmann (1826-1904)].

PubMed

Schmidt, G; Holubar, K

1990-01-01

Albert Reder von Schellmann (1826-1904) was an important syphilidologist of the Vienna Medical School in the second half of the nineteenth century. He went in for the dualistic concept of the origin of syphilis and ulcer caused by soft chancre. In 1870 - Reder became head of a third dermato-syphilidologic department in the "Josephinum" in Vienna, where military surgeons got their medical education. At the same time the two full professorships of dermatosyphilidology in the Vienna General Hospital were held by Ferdinand von Hebra (1816-1880) and Carl Ludwig Sigmund von Ilanor (1810-1883).

An enteric pathogen Salmonella enterica serovar Typhimurium suppresses tumor growth by downregulating CD44high and CD4T regulatory (Treg) cell expression in mice: the critical role of lipopolysaccharide and Braun lipoprotein in modulating tumor growth.

PubMed

Liu, T; Chopra, A K

2010-02-01

An antitumor activity associated with several bacterial pathogens, including Salmonella enterica serovar Typhimurium, has been reported; however, the underlying immunological mechanism(s) that lead to an antitumor effect are currently unclear. Furthermore, such pathogens cannot be used to suppress tumor growth because of their potential for causing sepsis. Recently, we reported the characterization of S. Typhimurium isogenic mutants from which Braun lipoprotein genes (lppA and B) and the multicopy repressor of high temperature requirement (msbB) gene were deleted. In a mouse infection model, two mutants, namely, lppB/msbB and lppAB/msbB, minimally induced proinflammatory cytokine production at high doses and were nonlethal to animals. We showed that immunization of mice with these mutants, followed by challenge with the wild-type S. Typhimurium, could significantly suppress tumor growth, as evidenced by an 88% regression in tumor size in lppB/msbB mutant-immunized animals over a 24-day period. However, the lppAB/msbB mutant alone was not effective in modulating tumor growth in mice, although the lppB/msbB mutant alone caused marginal regression in tumor size. Importantly, we showed that CD44(+) cells grew much faster than CD44(-) cells from human liver tumors in mice, leading us to examine the possibility that S. Typhimurium might downregulate CD44 in tumors and splenocytes of mice. Consequently, we found in S. Typhimurium-infected mice that tumor size regression could indeed be related to the downregulation of CD44(high) and CD4(+)CD25(+) T(reg) cells. Importantly, the role of lipopolysaccharide and Braun lipoprotein was critical in S. Typhimurium-induced antitumor immune responses. Taken together, we have defined new immune mechanisms leading to tumor suppression in mice by S. Typhimurium.

["Nicolaus Ficke... who practiced physiognomy, astrology, etc. was also a bad man"].

PubMed

Lenke, Nils; Roudet, Nicolas

2012-01-01

This arcticle summarizes what could be learned from newly discovered documents about the biography of Nicolas von Vicken, first known reader of Kepler's "Astronomia Nova" and Kepler's partner in an exchange of more than a dozen letters over several years. Von Vicken stems from a rich and influential family of merchants in Riga, made noble by the Polish King (who ruled Riga at the time) in 1580. His education included legal studies at the universities of Königsberg, Leipzig and Rostock, partially overlapping with a stay of ten years at the Polish court. There von Vicken pursued family business but also served in an official court role. In 1600/1 von Vicken switched sides and started to serve the Swedish ruler (and later king) Duke Carl IX, who was at war with Poland to gain control over Riga and Livonia. In 1602 a mission for Sweden to Northern Germany brought him in conflict with Francis II, Duke of Saxe-Lauenburg, who accused von Vicken of withholding money from him, which was supposed to be used for hiring troops. Von Vicken, together with his brother Heinrich, was imprisoned, but could flee. During a mission to Maximilian III, Archduke of Austria, in 1599/1600 von Vicken had been initiated as an alchemist and astrologer through reading the works of Paracelsus and his future stations in life were influenced by this. These include an attempt to get employed at the Saxon court in Dresden, and stays in Wolfenbiittel and Halberstadt, both ruled by Duke Henry Julius of Brunswick-Lüneburg. Von Vicken offered various astrological and alchemical services to the Duke and private investors. With one of them he got into a serious conflict over the alleged non-fillment of a contract to produce steel in an alchemical way. During that von Vicken got imprisoned twice, in 1609 and between 1611 and 1614. A subsequent attempt to get employed by Ernst of Schaumburg left us with several letters that detail von Vicken's alchemical and astrological thinking, two of these are published here in the appendix. Since 1603 von Vicken was also in the service of Emperor Rudolf II; again he got imprisoned in Prague at least once. An interesting speculation based on some hints in the documents is that after reading Paracelsus and during his time in Leipzig von Vicken authored a book on mining, that was later to become part of the works of the alleged medevial monk Basilius Valentinus.

An analytic resolution to the competition between Lyman-Werner radiation and metal winds in direct collapse black hole hosts

NASA Astrophysics Data System (ADS)

Agarwal, Bhaskar; Regan, John; Klessen, Ralf S.; Downes, Turlough P.; Zackrisson, Erik

2017-10-01

A near pristine atomic cooling halo close to a star forming galaxy offers a natural pathway for forming massive direct collapse black hole (DCBH) seeds, which could be the progenitors of the z > 6 redshift quasars. The close proximity of the haloes enables a sufficient Lyman-Werner flux to effectively dissociate H2 in the core of the atomic cooling halo. A mild background may also be required to delay star formation in the atomic cooling halo, often attributed to distant background galaxies. In this paper, we investigate the impact of metal pollution from both the background galaxies and the close star forming galaxy under extremely unfavourable conditions such as instantaneous metal mixing. We find that within the time window of DCBH formation, the level of pollution never exceeds the critical threshold (Zcr ˜ 1 × 10-5 Z⊙) and attains a maximum metallicity of Z ˜ 2 × 10- 6 Z⊙. As the system evolves, the metallicity eventually exceeds the critical threshold, long after the DCBH has formed.