Sample records for widest contiguous field

  1. 45 CFR 1308.13 - Eligibility criteria: Visual impairment including blindness.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... A child is visually impaired if: (1) The vision loss meets the definition of legal blindness in the... vision such that the widest diameter of the visual field subtends an angle no greater than 20 degrees. (b..., limited field of vision, cataracts, etc. ...

  2. 45 CFR 1308.13 - Eligibility criteria: Visual impairment including blindness.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... A child is visually impaired if: (1) The vision loss meets the definition of legal blindness in the... vision such that the widest diameter of the visual field subtends an angle no greater than 20 degrees. (b..., limited field of vision, cataracts, etc. ...

  3. 34 CFR 395.1 - Terms.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., DEPARTMENT OF EDUCATION VENDING FACILITY PROGRAM FOR THE BLIND ON FEDERAL AND OTHER PROPERTY Definitions... licensing agency to operate a vending facility on Federal or other property. (c) Blind person means a person... evidenced by a limitation to the field of vision in the better eye to such a degree that its widest diameter...

  4. One Hundred Years of Research: Prudent Aspirations

    ERIC Educational Resources Information Center

    Glass, Gene V.

    2016-01-01

    The statistical method "meta-analysis" is perhaps unique as a contribution to empirical inquiry of many types because it arose entirely within the practice of education research. In spite of its origins, meta-analysis has found its widest application and most important contributions in the field of medicine. Contrasting the success of…

  5. The performance of approximations of farm contiguity compared to contiguity defined using detailed geographical information in two sample areas in Scotland: implications for foot-and-mouth disease modelling.

    PubMed

    Flood, Jessica S; Porphyre, Thibaud; Tildesley, Michael J; Woolhouse, Mark E J

    2013-10-08

    When modelling infectious diseases, accurately capturing the pattern of dissemination through space is key to providing optimal recommendations for control. Mathematical models of disease spread in livestock, such as for foot-and-mouth disease (FMD), have done this by incorporating a transmission kernel which describes the decay in transmission rate with increasing Euclidean distance from an infected premises (IP). However, this assumes a homogenous landscape, and is based on the distance between point locations of farms. Indeed, underlying the spatial pattern of spread are the contact networks involved in transmission. Accordingly, area-weighted tessellation around farm point locations has been used to approximate field-contiguity and simulate the effect of contiguous premises (CP) culling for FMD. Here, geographic data were used to determine contiguity based on distance between premises' fields and presence of landscape features for two sample areas in Scotland. Sensitivity, positive predictive value, and the True Skill Statistic (TSS) were calculated to determine how point distance measures and area-weighted tessellation compared to the 'gold standard' of the map-based measures in identifying CPs. In addition, the mean degree and density of the different contact networks were calculated. Utilising point distances <1 km and <5 km as a measure for contiguity resulted in poor discrimination between map-based CPs/non-CPs (TSS 0.279-0.344 and 0.385-0.400, respectively). Point distance <1 km missed a high proportion of map-based CPs; <5 km point distance picked up a high proportion of map-based non-CPs as CPs. Area-weighted tessellation performed best, with reasonable discrimination between map-based CPs/non-CPs (TSS 0.617-0.737) and comparable mean degree and density. Landscape features altered network properties considerably when taken into account. The farming landscape is not homogeneous. Basing contiguity on geographic locations of field boundaries and including landscape features known to affect transmission into FMD models are likely to improve individual farm-level accuracy of spatial predictions in the event of future outbreaks. If a substantial proportion of FMD transmission events are by contiguous spread, and CPs should be assigned an elevated relative transmission rate, the shape of the kernel could be significantly altered since ability to discriminate between map-based CPs and non-CPs is different over different Euclidean distances.

  6. An extended moderate-depth contiguous layer of the Chandra Bootes field - additional pointings

    NASA Astrophysics Data System (ADS)

    Kraft, Ralph

    2016-09-01

    We propose 150ks (6x25ks) ACIS-I observations to supplement existing X-ray data in XBootes. These new observations will allow the expansion of relatively large contiguous ( 2deg2) region in Bootes covered at 40ks, i.e., 5-8x deeper than the nominal Bootes field. In concert with the recently approved 1.025 Ms Chandra Deep Wide-Field Survey, this additional deep layer of Bootes will (1) provide new insights into the dark matter halos and large-scale structures that host AGN; (2) allow new measurements of the distribution of X-ray luminosities and connections to host galaxy evolution.

  7. Adaptive optics for MOSAIC: design and performance of the wide(st)-field AO system for the E-ELT

    NASA Astrophysics Data System (ADS)

    Morris, Tim; Basden, Alastair; Buey, Tristan; Chemla, Fanny; Conan, Jean-Marc; Fitzsimons, Ewan; Fusco, Thierry; Gendron, Eric; Hammer, Francois; Jagourel, Pascal; Morel, Carine; Myers, Richard; Neichel, Benoit; Petit, Cyril; Rodrigues, Myriam; Rousset, Gérard

    2016-07-01

    MOSAIC is the proposed multiple-object spectrograph for the E-ELT that will utilise the widest possible field of view provided by the telescope. In terms of adaptive optics, there are two distinct operating modes required to meet the top-level science requirements. The MOSAIC High Multiplex Mode (HMM) requires either seeing-limited or GLAO correction within a 0.6 (NIR) and 0.9 (VIS) arcsecond sub-fields over the widest possible field for a few hundred objects. To achieve seeing limited operation whilst maintaining the maximum unvignetted field of view for scientific observation will require recreating some of the functionality present in the Pre-Focal Station relating to control of the E-ELT active optics. MOSAIC High Definition Mode Control (HDM) requires a 25% Ensquared Energy (EE) within 150mas in the H-band element for approximately 10 targets distributed across the full E-ELT field, implying the use of Multiple Object AO (MOAO). Initial studies have shown that to meet the EE requirements whilst maintaining high-sky coverage will require the combination of wavefront signals from both high-order NGS and LGS to provide a tomographic estimate for the correction to be applied to the open-loop MOAO DMs. In this paper we present the current MOSAIC AO design and provide the first performance estimates for the baseline instrument design. We then report on the various trade-offs that will be investigated throughout the course of the Phase A study, such as the requirement to mix NGS and LGS signals tomographically. Finally, we discuss how these will impact the AO architecture, the MOSAIC design and ultimately the scientific performance of this wide-field workhorse instrument at the E-ELT.

  8. AzTEC/ASTE 1.1 mm Deep Surveys: Number Counts and Clustering of Millimeter-bright Galaxies

    NASA Astrophysics Data System (ADS)

    Hatsukade, B.

    2011-11-01

    We present results of a 1.1 mm deep survey of the AKARI Deep Field South (ADF-S) with AzTEC mounted on the Atacama Submillimetre Telescope Experiment (ASTE). We obtained a map of 0.25 deg2 area with an rms noise level of 0.32-0.71 mJy. This is one of the deepest and widest maps thus far at millimetre and submillimetre wavelengths. We uncovered 198 sources with a significance of 3.5-15.6σ, providing the largest catalog of 1.1 mm sources in a contiguous region. Most of the sources are not detected in the far-infrared bands of the AKARI satellite, suggesting that they are mostly at z ≥ 1.5 given the detection limits. We construct differential and cumulative number counts of the ADF-S, the Subaru/XMM Newton Deep Field (SXDF), and the SSA 22 field surveyed by AzTEC/ASTE, which provide currently the tightest constraints on the faint end. The integration of the differential number counts of the ADF-S find that the contribution of 1.1 mm sources with ≥1 mJy to the cosmic infrared background (CIB) at 1.1 mm is 12-16%, suggesting that the large fraction of the CIB originates from faint sources of which number counts are not yet constrained. We estimate the cosmic star-formation rate density contributed by 1.1 mm sources with ≥1 mJy using the differential number counts and find that it is lower by about a factor of 5-10 compared to those derived from UV/optically-selected galaxies at z ~ 2-3. Clustering analyses of AzTEC sources in the ADF-S and the SXDF find that bright (>3 mJy) AzTEC sources are more strongly clustered than faint (< 3 mJy) AzTEC sources and the average mass of dark halos hosting bright AzTEC sources was calculated to be 1013-1014M⊙. Comparison of correlation length of AzTEC sources with other populations and with a bias evolution model suggests that dark halos hosting bright AzTEC sources evolve into systems of clusters at present universe and the AzTEC sources residing the dark halos evolve into massive elliptical galaxies located in the center of clusters.

  9. VizieR Online Data Catalog: H-ATLAS NGP LOFAR radio catalogue (Hardcastle+, 2016)

    NASA Astrophysics Data System (ADS)

    Hardcastle, M. J.; Gurkan, G.; van Weeren, R. J.; Williams, W. L.; Best, P. N.; de Gasperin, F.; Rafferty, D. A.; Read, S. C.; Sabater, J.; Shimwell, T. W.; Smith, D. J. B.; Tasse, C.; Bourne, N.; Brienza, M.; Bruggen, M.; Brunetti, G.; Chyzy, K. T.; Conway, J.; Dunne, L.; Eales, S. A.; Maddox, S. J.; Jarvis, M. J.; Mahony, E. K.; Morganti, R.; Prandoni, I.; Rottgering, H. J. A.; Valiante, E.; White, G. J.

    2018-01-01

    The NGP field was observed in four separate pointings, chosen to maximize sky covered, with the LOFAR HBA as part of the Surveys Key Science project. Observations used the HBADUALINNER mode, meaning that the station beams of core and remote stations roughly matched each other and giving the widest possible field of view. The first observation, which was made early on in LOFAR operations, was of slightly longer duration (~10h) than the others (~8h). International stations were included in some of the observations in 2014 but were not used in any of our analysis, which uses only the Dutch array. (1 data file).

  10. Wide-angle Optical Telescope for the EUSO Experiments

    NASA Technical Reports Server (NTRS)

    Hillman, L. W.; Takahaski, Y.; Zuccaro, A.; Lamb, D.; Pitalo, K.; Lopado, A.; Keys, A.

    2003-01-01

    Future spacebased air shower experiments, including the planned Extreme Universe Space Observatory (EUSO) mission, require a wide-angle telescope in the near-UV wavelengths 330 - 400 nm. Widest possible target aperture of earth's atmosphere, such as greater than 10(exp 5) square kilometers sr, can be viewed within the field-of-view of 30 degrees from space. EUSO's optical design is required to be compact, being constrained by the allocated mass and diameter for use in space. Two doublesided Fresnel lenses with 2.5-m diameter are chosen for the baseline design. It satisfies the imaging resolution of 0.1 degree over the 30-degree field of view.

  11. Large Deviations and Quasipotential for Finite State Mean Field Interacting Particle Systems

    DTIC Science & Technology

    2014-05-01

    The conclusion then follows by applying Lemma 4.4.2. 132 119 4.4.1 Iterative solver: The widest neighborhood structure We employ Gauss - Seidel ...nearest neighborhood structure described in Section 4.4.2. We use Gauss - Seidel iterative method for our numerical experiments. The Gauss - Seidel ...x ∈ Bh, M x ∈ Sh\\Bh, where M ∈ (V,∞) is a very large number, so that the iteration (4.5.1) converges quickly. For simplicity, we restrict our

  12. Bridging the "Widest Street in the World": Reflections on the History of Teacher Education

    ERIC Educational Resources Information Center

    Mirel, Jeffrey

    2011-01-01

    For at least a half century, education reformers have quipped that 120th Street in New York City, the street that separates Teachers College from the rest of Columbia University, "is the widest street in the world." Underlying this quip is the belief that Columbia's liberal arts faculty members regularly dismiss the child-centered educational…

  13. Comparison of the arithmetic and geometric means in estimating crown diameter and crown cross-sectional area

    Treesearch

    KaDonna Randolph

    2010-01-01

    The use of the geometric and arithmetic means for estimating tree crown diameter and crown cross-sectional area were examined for trees with crown width measurements taken at the widest point of the crown and perpendicular to the widest point of the crown. The average difference between the geometric and arithmetic mean crown diameters was less than 0.2 ft in absolute...

  14. Role of inhibitory control in modulating focal seizure spread.

    PubMed

    Liou, Jyun-You; Ma, Hongtao; Wenzel, Michael; Zhao, Mingrui; Baird-Daniel, Eliza; Smith, Elliot H; Daniel, Andy; Emerson, Ronald; Yuste, Rafael; Schwartz, Theodore H; Schevon, Catherine A

    2018-05-10

    Focal seizure propagation is classically thought to be spatially contiguous. However, distribution of seizures through a large-scale epileptic network has been theorized. Here, we used a multielectrode array, wide field calcium imaging, and two-photon calcium imaging to study focal seizure propagation pathways in an acute rodent neocortical 4-aminopyridine model. Although ictal neuronal bursts did not propagate beyond a 2-3-mm region, they were associated with hemisphere-wide field potential fluctuations and parvalbumin-positive interneuron activity outside the seizure focus. While bicuculline surface application enhanced contiguous seizure propagation, focal bicuculline microinjection at sites distant to the 4-aminopyridine focus resulted in epileptic network formation with maximal activity at the two foci. Our study suggests that both classical and epileptic network propagation can arise from localized inhibition defects, and that the network appearance can arise in the context of normal brain structure without requirement for pathological connectivity changes between sites.

  15. High-frequency field-deployable isotope analyzer for hydrological applications

    Treesearch

    Elena S.F. Berman; Manish Gupta; Chris Gabrielli; Tina Garland; Jeffrey J. McDonnell

    2009-01-01

    A high-frequency, field-deployable liquid water isotope analyzer was developed. The instrument was deployed for 4 contiguous weeks in the H. J. Andrews Experimental Forest Long-term Ecological Research site in western Oregon, where it was used for real-time measurement of the isotope ratios of precipitation and stream water during three large storm events. We were able...

  16. 46 CFR 154.174 - Transverse contiguous hull structure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Transverse contiguous hull structure. 154.174 Section... Equipment Hull Structure § 154.174 Transverse contiguous hull structure. (a) The transverse contiguous hull...) The transverse contiguous hull structure of a vessel having cargo containment systems with secondary...

  17. A causal contiguity effect that persists across time scales.

    PubMed

    Kiliç, Asli; Criss, Amy H; Howard, Marc W

    2013-01-01

    The contiguity effect refers to the tendency to recall an item from nearby study positions of the just recalled item. Causal models of contiguity suggest that recalled items are used as probes, causing a change in the memory state for subsequent recall attempts. Noncausal models of the contiguity effect assume the memory state is unaffected by recall per se, relying instead on the correlation between the memory states at study and at test to drive contiguity. We examined the contiguity effect in a probed recall task in which the correlation between the study context and the test context was disrupted. After study of several lists of words, participants were given probe words in a random order and were instructed to recall a word from the same list as the probe. The results showed both short-term and long-term contiguity effects. Because study order and test order are uncorrelated, these contiguity effects require a causal contiguity mechanism that operates across time scales.

  18. NATIONAL RESULTS FROM THE 2011 NATIONAL WETLAND CONDITION ASSESSMENT (NWCA) SOILS ANALYSIS

    EPA Science Inventory

    In 2011, US Environmental Protection Agency conducted the first National Wetland Condition Assessment (NWCA). Field crews conducted one-day surveys of over 1000 wetlands across the contiguous United States. For every wetland sampled, soils were collected by layer (i.e., horizon)...

  19. Aspects of three-dimensional strain at the margin of the extensional orogen, Virgin River depression area, Nevada, Utah, and Arizona

    USGS Publications Warehouse

    Anderson, R.E.; Barnhard, T.P.

    1993-01-01

    The Virgin River depression and surrounding mountains are Neogene features that are partly contiguous with the little-strained rocks of the structural transition to the Colorado Plateau province. This contiguity makes the area ideally suited for evaluating the sense, magnitude, and kinematics of Neogene deformation. Analysis along the strain boundary shows that, compared to the adjacent little-strained area, large-magnitude vertical deformation greatly exceeds extensional deformation and that significant amounts of lateral displacement approximately parallel the province boundary. Isostatic rebound following tectonic denudation is an unlikely direct cause of the strong vertical structural relief adjacent to the strain boundary. Instead, the observed structures are first-order features defining a three-dimensional strain field produced by approximately east-west extension, vertical structural attenuation, and extension-normal shortening. All major structural elements of the strain-boundary strain field are also found in the adjacent Basin and Range. -from Authors

  20. Wide swath imaging spectrometer utilizing a multi-modular design

    DOEpatents

    Chrisp, Michael P.

    2010-10-05

    A wide swath imaging spectrometer utilizing an array of individual spectrometer modules in the telescope focal plane to provide an extended field of view. The spectrometer modules with their individual detectors are arranged so that their slits overlap with motion on the scene providing contiguous spatial coverage. The number of modules can be varied to take full advantage of the field of view available from the telescope.

  1. Assessing the Added Value of Dynamical Downscaling Using the Standardized Precipitation Index

    EPA Science Inventory

    In this study, the Standardized Precipitation Index (SPI) is used to ascertain the added value of dynamical downscaling over the contiguous United States. WRF is used as a regional climate model (RCM) to dynamically downscale reanalysis fields to compare values of SPI over drough...

  2. Body stability and muscle and motor cortex activity during walking with wide stance

    PubMed Central

    Farrell, Brad J.; Bulgakova, Margarita A.; Beloozerova, Irina N.; Sirota, Mikhail G.

    2014-01-01

    Biomechanical and neural mechanisms of balance control during walking are still poorly understood. In this study, we examined the body dynamic stability, activity of limb muscles, and activity of motor cortex neurons [primarily pyramidal tract neurons (PTNs)] in the cat during unconstrained walking and walking with a wide base of support (wide-stance walking). By recording three-dimensional full-body kinematics we found for the first time that during unconstrained walking the cat is dynamically unstable in the forward direction during stride phases when only two diagonal limbs support the body. In contrast to standing, an increased lateral between-paw distance during walking dramatically decreased the cat's body dynamic stability in double-support phases and prompted the cat to spend more time in three-legged support phases. Muscles contributing to abduction-adduction actions had higher activity during stance, while flexor muscles had higher activity during swing of wide-stance walking. The overwhelming majority of neurons in layer V of the motor cortex, 82% and 83% in the forelimb and hindlimb representation areas, respectively, were active differently during wide-stance walking compared with unconstrained condition, most often by having a different depth of stride-related frequency modulation along with a different mean discharge rate and/or preferred activity phase. Upon transition from unconstrained to wide-stance walking, proximal limb-related neuronal groups subtly but statistically significantly shifted their activity toward the swing phase, the stride phase where most of body instability occurs during this task. The data suggest that the motor cortex participates in maintenance of body dynamic stability during locomotion. PMID:24790167

  3. 46 CFR 154.176 - Longitudinal contiguous hull structure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Longitudinal contiguous hull structure. 154.176 Section... Equipment Hull Structure § 154.176 Longitudinal contiguous hull structure. (a) The longitudinal contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the...

  4. 46 CFR 154.176 - Longitudinal contiguous hull structure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Longitudinal contiguous hull structure. 154.176 Section... Equipment Hull Structure § 154.176 Longitudinal contiguous hull structure. (a) The longitudinal contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the...

  5. 46 CFR 154.176 - Longitudinal contiguous hull structure.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Longitudinal contiguous hull structure. 154.176 Section... Equipment Hull Structure § 154.176 Longitudinal contiguous hull structure. (a) The longitudinal contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the...

  6. 46 CFR 154.176 - Longitudinal contiguous hull structure.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Longitudinal contiguous hull structure. 154.176 Section... Equipment Hull Structure § 154.176 Longitudinal contiguous hull structure. (a) The longitudinal contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the...

  7. 46 CFR 154.176 - Longitudinal contiguous hull structure.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Longitudinal contiguous hull structure. 154.176 Section... Equipment Hull Structure § 154.176 Longitudinal contiguous hull structure. (a) The longitudinal contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the...

  8. 46 CFR 154.178 - Contiguous hull structure: Heating system.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Contiguous hull structure: Heating system. 154.178... Equipment Hull Structure § 154.178 Contiguous hull structure: Heating system. The heating system for transverse and longitudinal contiguous hull structure must: (a) Be shown by a heat load calculation to have...

  9. 40 CFR 408.130 - Applicability; description of the breaded shrimp processing in the contiguous States subcategory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... breaded shrimp processing in the contiguous States subcategory. 408.130 Section 408.130 Protection of... SEAFOOD PROCESSING POINT SOURCE CATEGORY Breaded Shrimp Processing in the Contiguous States Subcategory § 408.130 Applicability; description of the breaded shrimp processing in the contiguous States...

  10. 40 CFR 408.130 - Applicability; description of the breaded shrimp processing in the contiguous States subcategory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... breaded shrimp processing in the contiguous States subcategory. 408.130 Section 408.130 Protection of... SEAFOOD PROCESSING POINT SOURCE CATEGORY Breaded Shrimp Processing in the Contiguous States Subcategory § 408.130 Applicability; description of the breaded shrimp processing in the contiguous States...

  11. 40 CFR 408.110 - Applicability; description of the Northern shrimp processing in the contiguous States subcategory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Northern shrimp processing in the contiguous States subcategory. 408.110 Section 408.110 Protection of... SEAFOOD PROCESSING POINT SOURCE CATEGORY Northern Shrimp Processing in the Contiguous States Subcategory § 408.110 Applicability; description of the Northern shrimp processing in the contiguous States...

  12. 40 CFR 408.110 - Applicability; description of the Northern shrimp processing in the contiguous States subcategory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Northern shrimp processing in the contiguous States subcategory. 408.110 Section 408.110 Protection of... SEAFOOD PROCESSING POINT SOURCE CATEGORY Northern Shrimp Processing in the Contiguous States Subcategory § 408.110 Applicability; description of the Northern shrimp processing in the contiguous States...

  13. 46 CFR 154.174 - Transverse contiguous hull structure.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Transverse contiguous hull structure. 154.174 Section... Equipment Hull Structure § 154.174 Transverse contiguous hull structure. (a) The transverse contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the standards of...

  14. 46 CFR 154.174 - Transverse contiguous hull structure.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Transverse contiguous hull structure. 154.174 Section... Equipment Hull Structure § 154.174 Transverse contiguous hull structure. (a) The transverse contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the standards of...

  15. 46 CFR 154.174 - Transverse contiguous hull structure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Transverse contiguous hull structure. 154.174 Section... Equipment Hull Structure § 154.174 Transverse contiguous hull structure. (a) The transverse contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the standards of...

  16. 46 CFR 154.174 - Transverse contiguous hull structure.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Transverse contiguous hull structure. 154.174 Section... Equipment Hull Structure § 154.174 Transverse contiguous hull structure. (a) The transverse contiguous hull structure of a vessel having cargo containment systems without secondary barriers must meet the standards of...

  17. Quantitative susceptibility mapping across two clinical field strengths: Contrast-to-noise ratio enhancement at 1.5T.

    PubMed

    Ippoliti, Matteo; Adams, Lisa C; Winfried, Brenner; Hamm, Bernd; Spincemaille, Pascal; Wang, Yi; Makowski, Marcus R

    2018-04-16

    Quantitative susceptibility mapping (QSM) is an MRI postprocessing technique that allows quantification of the spatial distribution of tissue magnetic susceptibility in vivo. Contributing sources include iron, blood products, calcium, myelin, and lipid content. To evaluate the reproducibility and consistency of QSM across clinical field strengths of 1.5T and 3T and to optimize the contrast-to-noise ratio (CNR) at 1.5T through bandwidth tuning. Prospective. Sixteen healthy volunteers (10 men, 6 women; age range 24-37; mean age 27.8 ± 3.2 years). 1.5T and 3T systems from the same vendor. Four spoiled gradient echo (SPGR) sequences were designed with different acquisition bandwidths. QSM reconstruction was achieved through a nonlinear morphology-enabled dipole inversion (MEDI) algorithm employing L1 regularization. CNR was calculated in seven regions of interest (ROIs), while reproducibility and consistency of QSM measurements were evaluated through voxel-based and region-specific linear correlation analyses and Bland-Altman plots. Interclass correlation, Wilcoxon rank sum test, linear regression analysis, Bland-Altman analysis, Welch's t-test. CNR analysis showed a statistically significant (P < 0.05) increase in four out of seven ROIs for the lowest bandwidth employed with respect to the highest (25.18% increase in CNR of caudate nucleus). All sequences reported an excellent correlation across field strength and bandwidth variation (R ≥ 0.96, widest limits of agreement from -18.7 to 25.8 ppb) in the ROI-based analysis, while the correlation was found to be good for the voxel-based analysis of averaged maps (R ≥ 0.90, widest limits of agreement from -9.3 to 9.1 ppb). CNR of QSM images reconstructed from 1.5T acquisitions can be enhanced through bandwidth tuning. MEDI-based QSM reconstruction demonstrated to be reproducible and consistent both across field strengths (1.5T and 3T) and bandwidth variation. 1 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018. © 2018 International Society for Magnetic Resonance in Medicine.

  18. No-insulation multi-width winding technique for high temperature superconducting magnet.

    PubMed

    Hahn, Seungyong; Kim, Youngjae; Keun Park, Dong; Kim, Kwangmin; Voccio, John P; Bascuñán, Juan; Iwasa, Yukikazu

    2013-10-21

    We present a No-Insulation ( NI ) Multi-Width ( MW ) winding technique for an HTS (high temperature superconductor) magnet consisting of double-pancake (DP) coils. The NI enables an HTS magnet self-protecting and the MW minimizes the detrimental anisotropy in current-carrying capacity of HTS tape by assigning tapes of multiple widths to DP coils within a stack, widest tape to the top and bottom sections and the narrowest in the midplane section. This paper presents fabrication and test results of an NI-MW HTS magnet and demonstrates the unique features of the NI-MW technique: self-protecting and enhanced field performance, unattainable with the conventional technique.

  19. Teaching the Concept of the Sampling Distribution of the Mean

    ERIC Educational Resources Information Center

    Aguinis, Herman; Branstetter, Steven A.

    2007-01-01

    The authors use proven cognitive and learning principles and recent developments in the field of educational psychology to teach the concept of the sampling distribution of the mean, which is arguably one of the most central concepts in inferential statistics. The proposed pedagogical approach relies on cognitive load, contiguity, and experiential…

  20. 46 CFR 154.180 - Contiguous hull structure: Welding procedure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Contiguous hull structure: Welding procedure. 154.180... Equipment Hull Structure § 154.180 Contiguous hull structure: Welding procedure. Welding procedure tests for contiguous hull structure designed for a temperature colder than −18 °C (0 °F) must meet § 54.05-15 and...

  1. A Causal Contiguity Effect That Persists across Time Scales

    ERIC Educational Resources Information Center

    Kilic, Asli; Criss, Amy H.; Howard, Marc W.

    2013-01-01

    The contiguity effect refers to the tendency to recall an item from nearby study positions of the just recalled item. Causal models of contiguity suggest that recalled items are used as probes, causing a change in the memory state for subsequent recall attempts. Noncausal models of the contiguity effect assume the memory state is unaffected by…

  2. 46 CFR 154.172 - Contiguous steel hull structure.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Contiguous steel hull structure. 154.172 Section 154.172... Structure § 154.172 Contiguous steel hull structure. (a) Except as allowed in paragraphs (b) and (c) of this... construction of the contiguous steel hull structure must meet the thickness and steel grade in Table 1 for the...

  3. 46 CFR 154.172 - Contiguous steel hull structure.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Contiguous steel hull structure. 154.172 Section 154.172... Structure § 154.172 Contiguous steel hull structure. (a) Except as allowed in paragraphs (b) and (c) of this... construction of the contiguous steel hull structure must meet the thickness and steel grade in Table 1 for the...

  4. 46 CFR 154.172 - Contiguous steel hull structure.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Contiguous steel hull structure. 154.172 Section 154.172... Structure § 154.172 Contiguous steel hull structure. (a) Except as allowed in paragraphs (b) and (c) of this... construction of the contiguous steel hull structure must meet the thickness and steel grade in Table 1 for the...

  5. 46 CFR 154.172 - Contiguous steel hull structure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Contiguous steel hull structure. 154.172 Section 154.172... Structure § 154.172 Contiguous steel hull structure. (a) Except as allowed in paragraphs (b) and (c) of this... construction of the contiguous steel hull structure must meet the thickness and steel grade in Table 1 for the...

  6. [General psychosomatics in children and adolescents].

    PubMed

    Begovac, Ivan; Votava-Raić, Ana

    2004-01-01

    The purpose of this study is a review of contemporary knowledge from the field of children and adolescent psychosomatics by using standard textbooks and journals. Data are chosen according to their importance and easy reference for a clinical study and scientific research. Psychosomatics can be defined as medicine of mutual relationships in the widest sense. It seems that factors of bio-psycho-social area participate in etiology and pathogenesis, i.e. complex genetic, developmental, psychodynamic, neuroanatomical, psychoneurophysiological, neurobiochemical, psychoneuroimmunological, psychoneuroendocrinal, familiar, social and probably other factors. Children and adolescent psychiatry, pediatrics are mutually complementary. In the medical-psychosomatic field there is consideration in the form of spatial-operative models that have to be amended through the concepts of unconscious and preconscious as well as through a temporal-systematic perspective. A team approach will be applied in a therapy.

  7. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of the...

  8. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of the...

  9. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of the...

  10. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of the...

  11. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of the...

  12. Multifocal visual evoked potential and automated perimetry abnormalities in strabismic amblyopes.

    PubMed

    Greenstein, Vivienne C; Eggers, Howard M; Hood, Donald C

    2008-02-01

    To compare visual field abnormalities obtained with standard automated perimetry (SAP) to those obtained with the multifocal visual evoked potential (mfVEP) technique in strabismic amblyopes. Humphrey 24-2 visual fields (HVF) and mfVEPs were obtained from each eye of 12 strabismic amblyopes. For the mfVEP, amplitudes and latencies were analyzed and probability plots were derived. Multifocal VEP and HVF hemifields were abnormal if they had clusters of two or more contiguous points at p < 0.01, or three or more contiguous points at p < 0.05 with at least one at p < 0.01. An eye was abnormal if it had an abnormal hemifield. On SAP, amblyopic eyes had significantly higher foveal thresholds (p = 0.003) and lower mean deviation values (p = 0.005) than fellow eyes. For the mfVEP, 11 amblyopic and 6 fellow eyes were abnormal. Of the 11 amblyopic eyes, 6 were abnormal on SAP. The deficits extended from the center to mid periphery. Monocular mfVEP latencies were significantly decreased for amblyopic eyes compared with control eyes (p < 0.0002). Both techniques revealed deficits in visual function across the visual field in strabismic amblyopes, but the mfVEP revealed deficits in fellow eyes and in more amblyopic eyes. In addition, mfVEP response latencies for amblyopic eyes were shorter than normal.

  13. Electro-Optic Analog/Digital Converter.

    DTIC Science & Technology

    electro - optic material and a source of linearly polarized light is arranged to transmit its light energy along each of the optical waveguides. Electrodes are disposed contiguous to the optical waveguides for impressing electric fields thereacross. An input signal potential is applied to the electrodes to produce electric fields of intensity relative to each of the waveguides such that causes phase shift and resultant change of polarization which can be detected as representative of a binary ’one’ or binary ’zero’ for each of the channel optical

  14. The Widest Practicable Dissemination: The NASA Technical Report Server

    NASA Technical Reports Server (NTRS)

    Nelson, Michael L.; Gottlich, Gretchen L.; Bianco, David J.; Binkley, Robert L.; Kellogg, Yvonne D.; Paulson, Sharon S.; Beaumont, Chris J.; Schmunk, Robert B.; Kurtz, Michael J.; Accomazzi, Alberto

    1995-01-01

    The National Aeronautics and Space Act of 1958 established NASA and charged it to "provide for the widest practicable and appropriate dissemination of information concerning [...] its activities and the results thereof." The search for innovative methods to distribute NASA s information lead a grass-roots team to create the NASA Technical Report Server (NTRS), which uses the World Wide Web and other popular Internet-based information systems as search engines. The NTRS is an inter-center effort which provides uniform access to various distributed publication servers residing on the Internet. Users have immediate desktop access to technical publications from NASA centers and institutes. The NTRS is comprised of several units, some constructed especially for inclusion in NTRS, and others that are existing NASA publication services that NTRS reuses. This paper presents the NTRS architecture, usage metrics, and the lessons learned while implementing and maintaining the services over the initial 6-month period. The NTRS is largely constructed with freely available software running on existing hardware. NTRS builds upon existing hardware and software, and the resulting additional exposure for the body of literature contained will allow NASA to ensure that its institutional knowledge base will continue to receive the widest practicable and appropriate dissemination.

  15. The widest practicable dissemination: The NASA technical report server

    NASA Technical Reports Server (NTRS)

    Nelson, Michael L.; Gottlich, Gretchen L.; Bianco, David J.; Binkley, Robert L.; Kellogg, Yvonne D.; Paulson, Sharon S.; Beaumont, Chris J.; Schmunk, Robert B.; Kurtz, Michael J.; Accomazzi, Alberto

    1995-01-01

    The National Aeronautics and Space Act of 1958 established NASA and charged it to 'provide for the widest practicable and appropriate dissemination of information concerning...its activities and the results thereof.' The search for innovative methods to distribute NASA's information lead a grass-roots team to create the NASA Technical Report Server (NTRS), which uses the World Wide Web and other popular Internet-based information systems as search engines. The NTRS is an inter-center effort which provides uniform access to various distributed publication servers residing on the Internet. Users have immediate desktop access to technical publications from NASA centers and institutes. The NTRS is comprised of several units, some constructed especially for inclusion in NTRS, and others that are existing NASA publication services that NTRS reuses. This paper presents the NTRS architecture, usage metrics, and the lessons learned while implementing and maintaining the services over the initial six-month period. The NTRS is largely constructed with freely available software running on existing hardware. NTRS builds upon existing hardware and software, and the resulting additional exposure for the body of literature contained will allow NASA to ensure that its institutional knowledge base will continue to receive the widest practicable and appropriate dissemination.

  16. Splitting Attention across the Two Visual Fields in Visual Short-Term Memory

    ERIC Educational Resources Information Center

    Delvenne, Jean-Francois; Holt, Jessica L.

    2012-01-01

    Humans have the ability to attentionally select the most relevant visual information from their extrapersonal world and to retain it in a temporary buffer, known as visual short-term memory (VSTM). Research suggests that at least two non-contiguous items can be selected simultaneously when they are distributed across the two visual hemifields. In…

  17. Pollen Competition as a Reproductive Isolation Barrier Represses Transgene Flow between Compatible and Co-Flowering Citrus Genotypes

    PubMed Central

    Pons, Elsa; Navarro, Antonio; Ollitrault, Patrick; Peña, Leandro

    2011-01-01

    Background/Objective Despite potential benefits granted by genetically modified (GM) fruit trees, their release and commercialization raises concerns about their potential environmental impact, and the transfer via pollen of transgenes to cross-compatible cultivars is deemed to be the greatest source for environmental exposure. Information compiled from field trials on GM trees is essential to propose measures to minimize the transgene dispersal. We have conducted a field trial of seven consecutive years to investigate the maximum frequency of pollen-mediated crop-to-crop transgene flow in a citrus orchard, and its relation to the genetic, phenological and environmental factors involved. Methodology/Principal Findings Three different citrus genotypes carrying the uidA (GUS) tracer marker gene (pollen donors) and a non-GM self-incompatible contiguous citrus genotype (recipient) were used in conditions allowing natural entomophilous pollination to occur. The examination of 603 to 2990 seeds per year showed unexpectedly low frequencies (0.17–2.86%) of transgene flow. Paternity analyses of the progeny of subsets of recipient plants using 10 microsatellite (SSR) loci demonstrated a higher mating competence of trees from another non-GM pollen source population that greatly limited the mating chance of the contiguous cross-compatible and flowering-synchronized transgenic pollen source. This mating superiority could be explained by a much higher pollen competition capacity of the non-GM genotypes, as was confirmed through mixed-hand pollinations. Conclusions/Significance Pollen competition strongly contributed to transgene confinement. Based on this finding, suitable isolation measures are proposed for the first time to prevent transgene outflow between contiguous plantings of citrus types that may be extendible to other entomophilous transgenic fruit tree species. PMID:21991359

  18. Pollen competition as a reproductive isolation barrier represses transgene flow between compatible and co-flowering citrus genotypes.

    PubMed

    Pons, Elsa; Navarro, Antonio; Ollitrault, Patrick; Peña, Leandro

    2011-01-01

    Despite potential benefits granted by genetically modified (GM) fruit trees, their release and commercialization raises concerns about their potential environmental impact, and the transfer via pollen of transgenes to cross-compatible cultivars is deemed to be the greatest source for environmental exposure. Information compiled from field trials on GM trees is essential to propose measures to minimize the transgene dispersal. We have conducted a field trial of seven consecutive years to investigate the maximum frequency of pollen-mediated crop-to-crop transgene flow in a citrus orchard, and its relation to the genetic, phenological and environmental factors involved. Three different citrus genotypes carrying the uidA (GUS) tracer marker gene (pollen donors) and a non-GM self-incompatible contiguous citrus genotype (recipient) were used in conditions allowing natural entomophilous pollination to occur. The examination of 603 to 2990 seeds per year showed unexpectedly low frequencies (0.17-2.86%) of transgene flow. Paternity analyses of the progeny of subsets of recipient plants using 10 microsatellite (SSR) loci demonstrated a higher mating competence of trees from another non-GM pollen source population that greatly limited the mating chance of the contiguous cross-compatible and flowering-synchronized transgenic pollen source. This mating superiority could be explained by a much higher pollen competition capacity of the non-GM genotypes, as was confirmed through mixed-hand pollinations. Pollen competition strongly contributed to transgene confinement. Based on this finding, suitable isolation measures are proposed for the first time to prevent transgene outflow between contiguous plantings of citrus types that may be extendible to other entomophilous transgenic fruit tree species.

  19. Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma

    ClinicalTrials.gov

    2018-02-05

    Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage II Grade 1 Contiguous Follicular Lymphoma; Stage II Grade 1 Non-Contiguous Follicular Lymphoma; Stage II Grade 2 Contiguous Follicular Lymphoma; Stage II Grade 2 Non-Contiguous Follicular Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma

  20. No-insulation multi-width winding technique for high temperature superconducting magnet

    PubMed Central

    Hahn, Seungyong; Kim, Youngjae; Keun Park, Dong; Kim, Kwangmin; Voccio, John P.; Bascuñán, Juan; Iwasa, Yukikazu

    2013-01-01

    We present a No-Insulation (NI) Multi-Width (MW) winding technique for an HTS (high temperature superconductor) magnet consisting of double-pancake (DP) coils. The NI enables an HTS magnet self-protecting and the MW minimizes the detrimental anisotropy in current-carrying capacity of HTS tape by assigning tapes of multiple widths to DP coils within a stack, widest tape to the top and bottom sections and the narrowest in the midplane section. This paper presents fabrication and test results of an NI-MW HTS magnet and demonstrates the unique features of the NI-MW technique: self-protecting and enhanced field performance, unattainable with the conventional technique. PMID:24255549

  1. Management software for a universal device communication controller: application to monitoring and computerized infusions.

    PubMed

    Coussaert, E J; Cantraine, F R

    1996-11-01

    We designed a virtual device for a local area network observing, operating and connecting devices to a personal computer. To keep the widest field of application, we proceeded by using abstraction and specification rules of software engineering in the design and implementation of the hardware and software for the Infusion Monitor. We specially built a box of hardware to interface multiple medical instruments with different communication protocols to a PC via a single serial port. We called that box the Universal Device Communication Controller (UDCC). The use of the virtual device driver is illustrated by the Infusion Monitor implemented for the anaesthesia and intensive care workstation.

  2. Resolved Companions of Cepheids as Seen by HST and XMM

    NASA Astrophysics Data System (ADS)

    Evans, Nancy Remage; Bond, Howard E.; Schaefer, Gail; Mason, Brian D.; Tingle, Evan; Karovska, Margarita; Pillitteri, Ignazio; Wolk, Scott J.; Guinan, Edward F.; Engle, Scott G.

    2016-01-01

    We have conducted a survey of 70 classical Cepheids with the Hubble Wide Field Camera3 (WFC3) to identify possible resolved companions. Data cover the range of 0.3" to 20" which typically corresponds to 200 AU to 0.1 pc. At present only possible companions greater than 5" from the Cepheid are discussed, since closer companions require a sophisticated point spread correction for the light of the much brighter Cepheid. We have followed up a subset of the possible resolved companions with XMM observations to determine whether they are young (X-ray active) enough to be physical companions of the Cepheids. We estimate that 4% of the Cepheids have a physical resolved companion, with the widest having a separation of 4000 AU. The one wider young star is in the field of S Nor, but since it is a cluster member, the companion is not assumed to be gravitationally bound to the Cepheid.

  3. Skin dose differences between intensity-modulated radiation therapy and volumetric-modulated arc therapy and between boost and integrated treatment regimens for treating head and neck and other cancer sites in patients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Penoncello, Gregory P.; Ding, George X., E-mail: george.ding@vanderbilt.edu

    The purpose of this study was (1) to evaluate dose to skin between volumetric-modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) treatment techniques for target sites in the head and neck, pelvis, and brain and (2) to determine if the treatment dose and fractionation regimen affect the skin dose between traditional sequential boost and integrated boost regimens for patients with head and neck cancer. A total of 19 patients and 48 plans were evaluated. The Eclipse (v11) treatment planning system was used to plan therapy in 9 patients with head and neck cancer, 5 patients with prostate cancer, andmore » 5 patients with brain cancer with VMAT and static-field IMRT. The mean skin dose and the maximum dose to a contiguous volume of 2 cm{sup 3} for head and neck plans and brain plans and a contiguous volume of 5 cm{sup 3} for pelvis plans were compared for each treatment technique. Of the 9 patients with head and neck cancer, 3 underwent an integrated boost regimen. One integrated boost plan was replanned with IMRT and VMAT using a traditional boost regimen. For target sites located in the head and neck, VMAT reduced the mean dose and contiguous hot spot most noticeably in the shoulder region by 5.6% and 5.4%, respectively. When using an integrated boost regimen, the contiguous hot spot skin dose in the shoulder was larger on average than a traditional boost pattern by 26.5% and the mean skin dose was larger by 1.7%. VMAT techniques largely decrease the contiguous hot spot in the skin in the pelvis by an average of 36% compared with IMRT. For the same target coverage, VMAT can reduce the skin dose in all the regions of the body, but more noticeably in the shoulders in patients with head and neck and pelvis cancer. We also found that using integrated boost regimens in patients with head and neck cancer leads to higher shoulder skin doses compared with traditional boost regimens.« less

  4. 33 CFR 117.17 - Signalling for contiguous drawbridges.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Signalling for contiguous... SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS General Requirements § 117.17 Signalling for contiguous drawbridges. When a vessel must past two or more drawbridges close together, the opening signal is given for...

  5. 33 CFR 117.17 - Signalling for contiguous drawbridges.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Signalling for contiguous... SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS General Requirements § 117.17 Signalling for contiguous drawbridges. When a vessel must past two or more drawbridges close together, the opening signal is given for...

  6. 46 CFR 154.180 - Contiguous hull structure: Welding procedure.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Contiguous hull structure: Welding procedure. 154.180 Section 154.180 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS... Equipment Hull Structure § 154.180 Contiguous hull structure: Welding procedure. Welding procedure tests for...

  7. 46 CFR 154.180 - Contiguous hull structure: Welding procedure.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Contiguous hull structure: Welding procedure. 154.180 Section 154.180 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS... Equipment Hull Structure § 154.180 Contiguous hull structure: Welding procedure. Welding procedure tests for...

  8. 46 CFR 154.180 - Contiguous hull structure: Welding procedure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Contiguous hull structure: Welding procedure. 154.180 Section 154.180 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS... Equipment Hull Structure § 154.180 Contiguous hull structure: Welding procedure. Welding procedure tests for...

  9. 46 CFR 154.180 - Contiguous hull structure: Welding procedure.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Contiguous hull structure: Welding procedure. 154.180 Section 154.180 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS... Equipment Hull Structure § 154.180 Contiguous hull structure: Welding procedure. Welding procedure tests for...

  10. 33 CFR 117.17 - Signalling for contiguous drawbridges.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Signalling for contiguous... SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS General Requirements § 117.17 Signalling for contiguous drawbridges. When a vessel must past two or more drawbridges close together, the opening signal is given for...

  11. 33 CFR 117.17 - Signalling for contiguous drawbridges.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Signalling for contiguous... SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS General Requirements § 117.17 Signalling for contiguous drawbridges. When a vessel must past two or more drawbridges close together, the opening signal is given for...

  12. 33 CFR 117.17 - Signalling for contiguous drawbridges.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Signalling for contiguous... SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS General Requirements § 117.17 Signalling for contiguous drawbridges. When a vessel must past two or more drawbridges close together, the opening signal is given for...

  13. Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

    ClinicalTrials.gov

    2018-02-08

    Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Previously Treated Myelodysplastic Syndrome; Refractory Chronic Lymphocytic Leukemia; Refractory Plasma Cell Myeloma; Waldenstrom Macroglobulinemia; Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL; Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11; Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA; Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Lymphoma; Childhood Myelodysplastic Syndrome; Stage II Contiguous Adult Burkitt Lymphoma; Stage II Contiguous Adult Diffuse Large Cell Lymphoma; Stage II Contiguous Adult Diffuse Mixed Cell Lymphoma; Stage II Contiguous Adult Diffuse Small Cleaved Cell Lymphoma; Stage II Adult Contiguous Immunoblastic Lymphoma; Stage II Contiguous Adult Lymphoblastic Lymphoma; Stage II Grade 1 Contiguous Follicular Lymphoma; Stage II Grade 2 Contiguous Follicular Lymphoma; Stage II Grade 3 Contiguous Follicular Lymphoma; Stage II Contiguous Mantle Cell Lymphoma; Stage II Non-Contiguous Adult Burkitt Lymphoma; Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma; Stage II Non-Contiguous Adult Diffuse Mixed Cell Lymphoma; Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma; Stage II Adult Non-Contiguous Immunoblastic Lymphoma; Stage II Non-Contiguous Adult Lymphoblastic Lymphoma; Stage II Grade 1 Non-Contiguous Follicular Lymphoma; Stage II Grade 2 Non-Contiguous Follicular Lymphoma; Stage II Grade 3 Non-Contiguous Follicular Lymphoma; Stage II Non-Contiguous Mantle Cell Lymphoma; Stage II Small Lymphocytic Lymphoma; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Burkitt Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Recurrent Childhood Hodgkin Lymphoma; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Secondary Myelodysplastic Syndrome; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Immunoblastic Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Burkitt Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Burkitt Lymphoma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Burkitt Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Burkitt Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma

  14. Spatial Contiguity and Incidental Learning in Multimedia Environments

    ERIC Educational Resources Information Center

    Paek, Seungoh; Hoffman, Daniel L.; Saravanos, Antonios

    2017-01-01

    Drawing on dual-process theories of cognitive function, the degree to which spatial contiguity influences incidental learning outcomes was examined. It was hypothesized that spatial contiguity would mediate what was learned even in the absence of an explicit learning goal. To test this hypothesis, 149 adults completed a multimedia-related task…

  15. 33 CFR 2.28 - Contiguous zone.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Contiguous zone. 2.28 Section 2.28 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL JURISDICTION Jurisdictional Terms § 2.28 Contiguous zone. (a) For the purposes of the Federal Water Pollution Control Act (33...

  16. 46 CFR 108.175 - Contiguous locations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Contiguous locations. 108.175 Section 108.175 Shipping... EQUIPMENT Construction and Arrangement Classified Locations § 108.175 Contiguous locations. An enclosed space that has direct access to a Division 1 or Division 2 location is the same division as that...

  17. 13 CFR 123.600 - Are economic injury disaster loans under this subpart limited to the geographic areas contiguous...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the declared disaster areas and the contiguous geographic areas to small business concerns that have... under this subpart limited to the geographic areas contiguous to the declared disaster areas? 123.600 Section 123.600 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION DISASTER LOAN PROGRAM...

  18. 46 CFR 154.172 - Contiguous steel hull structure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Contiguous steel hull structure. 154.172 Section 154.172... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Hull Structure § 154.172 Contiguous steel hull structure. (a) Except as allowed in paragraphs (b) and (c) of this...

  19. 40 CFR 408.120 - Applicability; description of the Southern non-breaded shrimp processing in the contiguous States...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Southern non-breaded shrimp processing in the contiguous States subcategory. 408.120 Section 408.120... CANNED AND PRESERVED SEAFOOD PROCESSING POINT SOURCE CATEGORY Southern Non-Breaded Shrimp Processing in... shrimp processing in the contiguous States subcategory. The provisions of this subpart are applicable to...

  20. 40 CFR 408.120 - Applicability; description of the Southern non-breaded shrimp processing in the contiguous States...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Southern non-breaded shrimp processing in the contiguous States subcategory. 408.120 Section 408.120... CANNED AND PRESERVED SEAFOOD PROCESSING POINT SOURCE CATEGORY Southern Non-Breaded Shrimp Processing in... shrimp processing in the contiguous States subcategory. The provisions of this subpart are applicable to...

  1. A Comparison of Weights Matrices on Computation of Dengue Spatial Autocorrelation

    NASA Astrophysics Data System (ADS)

    Suryowati, K.; Bekti, R. D.; Faradila, A.

    2018-04-01

    Spatial autocorrelation is one of spatial analysis to identify patterns of relationship or correlation between locations. This method is very important to get information on the dispersal patterns characteristic of a region and linkages between locations. In this study, it applied on the incidence of Dengue Hemorrhagic Fever (DHF) in 17 sub districts in Sleman, Daerah Istimewa Yogyakarta Province. The link among location indicated by a spatial weight matrix. It describe the structure of neighbouring and reflects the spatial influence. According to the spatial data, type of weighting matrix can be divided into two types: point type (distance) and the neighbourhood area (contiguity). Selection weighting function is one determinant of the results of the spatial analysis. This study use queen contiguity based on first order neighbour weights, queen contiguity based on second order neighbour weights, and inverse distance weights. Queen contiguity first order and inverse distance weights shows that there is the significance spatial autocorrelation in DHF, but not by queen contiguity second order. Queen contiguity first and second order compute 68 and 86 neighbour list

  2. Ultra High Resolution Imaging of Enceladus Tiger Stripe Thermal Emission with Cassini CIRS

    NASA Astrophysics Data System (ADS)

    Spencer, John R.; Gorius, Nicolas; Howett, Carly; Verbiscer, Anne J.; Cassini CIRS Team

    2017-10-01

    In October 2015, Cassini flew within 48 km of Enceladus’ south pole. The spacecraft attitude was fixed during the flyby, but the roll angle of the spacecraft was chosen so that the remote sensing instrument fields of view passed over Damascus, Baghdad, and Cairo Sulci. The Composite Infrared Spectrometer (CIRS) instrument obtained a single interferometer scan during the flyby, using a special mode, enabled by a flight software update, which bypassed numerical filters to improve the fidelity of the interferograms. This generated a total of 11 interferograms, at 5 contiguous spatial locations for each of the 7 - 9 micron (FP4) and 9 - 17 micron (FP3) focal planes, and a single larger field of view for the 17 - 500 micron focal plane (FP1). Strong spikes were seen in the interferograms when crossing each of the sulci, due to the rapid passage of warm material through the field of view. For FP3 and FP4, the temporal variations of the signals from the 5 contiguous detectors can be used to generated 5-pixel-wide images of the thermal emission, which show excellent agreement between the two focal planes. FP3 and FP4 spatial resolution, limited along track by the 5 msec time sampling of the interferogram, and across track by the CIRS field of view, is a remarkable 40 x 40 meters. At this resolution, the tiger stripe thermal emission shows a large amount of structure, including both continuous emission along the fractures, discrete hot spots less than 100 meters across, and extended emission with complex structure.

  3. Diffusion bonding

    DOEpatents

    Anderson, Robert C.

    1976-06-22

    1. A method for joining beryllium to beryllium by diffusion bonding, comprising the steps of coating at least one surface portion of at least two beryllium pieces with nickel, positioning a coated surface portion in a contiguous relationship with an other surface portion, subjecting the contiguously disposed surface portions to an environment having an atmosphere at a pressure lower than ambient pressure, applying a force upon the beryllium pieces for causing the contiguous surface portions to abut against each other, heating the contiguous surface portions to a maximum temperature less than the melting temperature of the beryllium, substantially uniformly decreasing the applied force while increasing the temperature after attaining a temperature substantially above room temperature, and maintaining a portion of the applied force at a temperature corresponding to about maximum temperature for a duration sufficient to effect the diffusion bond between the contiguous surface portions.

  4. Clustering of Multivariate Geostatistical Data

    NASA Astrophysics Data System (ADS)

    Fouedjio, Francky

    2017-04-01

    Multivariate data indexed by geographical coordinates have become omnipresent in the geosciences and pose substantial analysis challenges. One of them is the grouping of data locations into spatially contiguous clusters so that data locations belonging to the same cluster have a certain degree of homogeneity while data locations in the different clusters have to be as different as possible. However, groups of data locations created through classical clustering techniques turn out to show poor spatial contiguity, a feature obviously inconvenient for many geoscience applications. In this work, we develop a clustering method that overcomes this problem by accounting the spatial dependence structure of data; thus reinforcing the spatial contiguity of resulting cluster. The capability of the proposed clustering method to provide spatially contiguous and meaningful clusters of data locations is assessed using both synthetic and real datasets. Keywords: clustering, geostatistics, spatial contiguity, spatial dependence.

  5. Linking species richness curves from non-contiguous sampling to contiguous-nested SAR: An empirical study

    NASA Astrophysics Data System (ADS)

    Lazarina, Maria; Kallimanis, Athanasios S.; Pantis, John D.; Sgardelis, Stefanos P.

    2014-11-01

    The species-area relationship (SAR) is one of the few generalizations in ecology. However, many different relationships are denoted as SARs. Here, we empirically evaluated the differences between SARs derived from nested-contiguous and non-contiguous sampling designs, using plants, birds and butterflies datasets from Great Britain, Greece, Massachusetts, New York and San Diego. The shape of SAR depends on the sampling scheme, but there is little empirical documentation on the magnitude of the deviation between different types of SARs and the factors affecting it. We implemented a strictly nested sampling design to construct nested-contiguous SAR (SACR), and systematic nested but non-contiguous, and random designs to construct non-contiguous species richness curves (SASRs for systematic and SACs for random designs) per dataset. The SACR lay below any SASR and most of the SACs. The deviation between them was related to the exponent f of the power law relationship between sampled area and extent. The lower the exponent f, the higher was the deviation between the curves. We linked SACR to SASR and SAC through the concept of "effective" area (Ae), i.e. the nested-contiguous area containing equal number of species with the accumulated sampled area (AS) of a non-contiguous sampling. The relationship between effective and sampled area was modeled as log(Ae) = klog(AS). A Generalized Linear Model was used to estimate the values of k from sampling design and dataset properties. The parameter k increased with the average distance between samples and with beta diversity, while k decreased with f. For both systematic and random sampling, the model performed well in predicting effective area in both the training set and in the test set which was totally independent from the training one. Through effective area, we can link different types of species richness curves based on sampling design properties, sampling effort, spatial scale and beta diversity patterns.

  6. A fosmid cloning strategy for detecting the widest possible spectrum of microbes from the international space station drinking water system.

    PubMed

    Choi, Sangdun; Chang, Mi Sook; Stuecker, Tara; Chung, Christine; Newcombe, David A; Venkateswaran, Kasthuri

    2012-12-01

    In this study, fosmid cloning strategies were used to assess the microbial populations in water from the International Space Station (ISS) drinking water system (henceforth referred to as Prebiocide and Tank A water samples). The goals of this study were: to compare the sensitivity of the fosmid cloning strategy with that of traditional culture-based and 16S rRNA-based approaches and to detect the widest possible spectrum of microbial populations during the water purification process. Initially, microbes could not be cultivated, and conventional PCR failed to amplify 16S rDNA fragments from these low biomass samples. Therefore, randomly primed rolling-circle amplification was used to amplify any DNA that might be present in the samples, followed by size selection by using pulsed-field gel electrophoresis. The amplified high-molecular-weight DNA from both samples was cloned into fosmid vectors. Several hundred clones were randomly selected for sequencing, followed by Blastn/Blastx searches. Sequences encoding specific genes from Burkholderia, a species abundant in the soil and groundwater, were found in both samples. Bradyrhizobium and Mesorhizobium, which belong to rhizobia, a large community of nitrogen fixers often found in association with plant roots, were present in the Prebiocide samples. Ralstonia, which is prevalent in soils with a high heavy metal content, was detected in the Tank A samples. The detection of many unidentified sequences suggests the presence of potentially novel microbial fingerprints. The bacterial diversity detected in this pilot study using a fosmid vector approach was higher than that detected by conventional 16S rRNA gene sequencing.

  7. Hyperspectral remote sensing for terrestrial applications

    USGS Publications Warehouse

    Thenkabail, Prasad S.; Teluguntla, Pardhasaradhi G.; Murali Krishna Gumma,; Venkateswarlu Dheeravath,

    2015-01-01

    Remote sensing data are considered hyperspectral when the data are gathered from numerous wavebands, contiguously over an entire range of the spectrum (e.g., 400–2500 nm). Goetz (1992) defines hyperspectral remote sensing as “The acquisition of images in hundreds of registered, contiguous spectral bands such that for each picture element of an image it is possible to derive a complete reflectance spectrum.” However, Jensen (2004) defines hyperspectral remote sensing as “The simultaneous acquisition of images in many relatively narrow, contiguous and/or non contiguous spectral bands throughout the ultraviolet, visible, and infrared portions of the electromagnetic spectrum.

  8. Multilevel non-contiguous spinal injuries: incidence and patterns based on whole spine MRI.

    PubMed

    Kanna, Rishi Mugesh; Gaike, Chandrasekar V; Mahesh, Anupama; Shetty, Ajoy Prasad; Rajasekaran, S

    2016-04-01

    Multi-level non-contiguous spinal injuries are not uncommon and their incidence varies from 1.6 to 77% depending on the type of imaging modality used. Delayed diagnosis and missed spinal injuries in non-contiguous spine fractures have been frequently described which can result in significant pain, deformity and neurological deficit. The efficacy of whole spine MRI in detecting asymptomatic significant vertebral fractures is not known. Consecutive spinal injury patients treated between 2011 and 2013 were retrospectively evaluated based on clinical and radiographic records. Patients' demographics, mode of injury, presence of associated injuries, clinical symptoms and the presence of neurological deficit were studied. Radiographs of the fractured region and whole spine MRI were evaluated for the presence of multi-level injuries. Among 484 patients, 95 (19.62%) patients had multilevel injuries including 86 (17.76%) with non-contiguous injuries. Five common patterns of non-contiguous spinal injuries were observed. Pattern I: cervical and thoracic--29.1%, Pattern II: thoracolumbar and lumbosacral--22.1%, Pattern III: thoracic and thoracolumbar--12.8 %, Pattern IV: cervical and thoracolumbar--9.1% and Pattern V: lumbosacral and associated injuries--9.0 %. The incidence of intra-regional non-contiguous injuries was 17.4%. Whole spine MRI scan detected 24 (28.6%) missed secondary injuries of which 5 were unstable. The incidence of multilevel non-contiguous spine injury using whole spine MRI imaging is 17.76%. Five different patterns of multi-level non-contiguous injuries were found with the most common pattern being the cervical and thoracic level injuries. The incidence of unstable injuries can be as high as 21% of missed secondary injuries.

  9. Skin dose differences between intensity-modulated radiation therapy and volumetric-modulated arc therapy and between boost and integrated treatment regimens for treating head and neck and other cancer sites in patients.

    PubMed

    Penoncello, Gregory P; Ding, George X

    2016-01-01

    The purpose of this study was (1) to evaluate dose to skin between volumetric-modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) treatment techniques for target sites in the head and neck, pelvis, and brain and (2) to determine if the treatment dose and fractionation regimen affect the skin dose between traditional sequential boost and integrated boost regimens for patients with head and neck cancer. A total of 19 patients and 48 plans were evaluated. The Eclipse (v11) treatment planning system was used to plan therapy in 9 patients with head and neck cancer, 5 patients with prostate cancer, and 5 patients with brain cancer with VMAT and static-field IMRT. The mean skin dose and the maximum dose to a contiguous volume of 2cm(3) for head and neck plans and brain plans and a contiguous volume of 5cm(3) for pelvis plans were compared for each treatment technique. Of the 9 patients with head and neck cancer, 3 underwent an integrated boost regimen. One integrated boost plan was replanned with IMRT and VMAT using a traditional boost regimen. For target sites located in the head and neck, VMAT reduced the mean dose and contiguous hot spot most noticeably in the shoulder region by 5.6% and 5.4%, respectively. When using an integrated boost regimen, the contiguous hot spot skin dose in the shoulder was larger on average than a traditional boost pattern by 26.5% and the mean skin dose was larger by 1.7%. VMAT techniques largely decrease the contiguous hot spot in the skin in the pelvis by an average of 36% compared with IMRT. For the same target coverage, VMAT can reduce the skin dose in all the regions of the body, but more noticeably in the shoulders in patients with head and neck and pelvis cancer. We also found that using integrated boost regimens in patients with head and neck cancer leads to higher shoulder skin doses compared with traditional boost regimens. Copyright © 2016 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

  10. Increased head circumference

    MedlinePlus

    ... page: //medlineplus.gov/ency/article/003305.htm Increased head circumference To use the sharing features on this page, please enable JavaScript. Increased head circumference is when the measured distance around the widest ...

  11. EPA Accessibility Statement

    EPA Pesticide Factsheets

    EPA is committed to making its websites and other electronic and information technology (EIT) accessible to the widest possible audience, including people with disabilities, in accordance with Section 508 of the Rehabilitation Act.

  12. Parcels versus pixels: modeling agricultural land use across broad geographic regions using parcel-based field boundaries

    USGS Publications Warehouse

    Sohl, Terry L.; Dornbierer, Jordan; Wika, Steve; Sayler, Kristi L.; Quenzer, Robert

    2017-01-01

    Land use and land cover (LULC) change occurs at a local level within contiguous ownership and management units (parcels), yet LULC models primarily use pixel-based spatial frameworks. The few parcel-based models being used overwhelmingly focus on small geographic areas, limiting the ability to assess LULC change impacts at regional to national scales. We developed a modified version of the Forecasting Scenarios of land use change model to project parcel-based agricultural change across a large region in the United States Great Plains. A scenario representing an agricultural biofuel scenario was modeled from 2012 to 2030, using real parcel boundaries based on contiguous ownership and land management units. The resulting LULC projection provides a vastly improved representation of landscape pattern over existing pixel-based models, while simultaneously providing an unprecedented combination of thematic detail and broad geographic extent. The conceptual approach is practical and scalable, with potential use for national-scale projections.

  13. Lenalidomide And Rituximab as Maintenance Therapy in Treating Patients With B-Cell Non-Hodgkin Lymphoma

    ClinicalTrials.gov

    2015-11-25

    Adult Non-Hodgkin Lymphoma; Adult Grade III Lymphomatoid Granulomatosis; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Waldenstrom Macroglobulinemia

  14. Improving draft genome contiguity with reference-derived in silico mate-pair libraries.

    PubMed

    Grau, José Horacio; Hackl, Thomas; Koepfli, Klaus-Peter; Hofreiter, Michael

    2018-05-01

    Contiguous genome assemblies are a highly valued biological resource because of the higher number of completely annotated genes and genomic elements that are usable compared to fragmented draft genomes. Nonetheless, contiguity is difficult to obtain if only low coverage data and/or only distantly related reference genome assemblies are available. In order to improve genome contiguity, we have developed Cross-Species Scaffolding-a new pipeline that imports long-range distance information directly into the de novo assembly process by constructing mate-pair libraries in silico. We show how genome assembly metrics and gene prediction dramatically improve with our pipeline by assembling two primate genomes solely based on ∼30x coverage of shotgun sequencing data.

  15. Communications availability: Estimation studies at AMSC

    NASA Technical Reports Server (NTRS)

    Sigler, C. Edward, Jr.

    1994-01-01

    The results of L-band communications availability work performed to date are presented. Results include a L-band communications availability estimate model and field propagation trials using an INMARSAT-M terminal. American Mobile Satellite Corporation's (AMSC's) primary concern centers on availability of voice communications intelligibility, with secondary concerns for circuit-switched data and fax. The model estimates for representative terrain/vegetation areas are applied to the contiguous U.S. for overall L-band communications availability estimates.

  16. Semantic Cuing and the Scale Insensitivity of Recency and Contiguity

    PubMed Central

    Polyn, Sean M.; Erlikhman, Gennady; Kahana, Michael J.

    2012-01-01

    In recalling a set of previously experienced events, people exhibit striking effects of recency, contiguity, and similarity: Recent items tend to be recalled best and first, and items that were studied in neighboring positions or that are similar to one another in some other way tend to evoke one another during recall. Effects of recency and contiguity have most often been investigated in tasks that require people to recall random word lists. Similarity effects have most often been studied in tasks that require people to recall categorized word lists. Here we examine recency and contiguity effects in lists composed of items drawn from 3 distinct taxonomic categories and in which items from a given category are temporally separated from one another by items from other categories, all of which are tested for recall. We find evidence for long-term recency and for long-range contiguity, bolstering support for temporally sensitive models of memory and highlighting the importance of understanding the interaction between temporal and semantic information during memory search. PMID:21299330

  17. 14 CFR 99.43 - Contiguous U.S. ADIZ.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Contiguous U.S. ADIZ. 99.43 Section 99.43 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... Zones § 99.43 Contiguous U.S. ADIZ. The area bounded by a line from 43°15′N, 65°55′W; 44°21′N; 67°16′W...

  18. 32 CFR 310.38 - Training methodology and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... procedures. (a) Each DoD Component is responsible for the development of training procedures and methodology... widest possible audience. Web-based training and video conferencing have been effective means to provide...

  19. Possible Sulfate Deposits in West Melas Chasma

    NASA Image and Video Library

    2016-05-04

    Melas Chasma is the widest segment of Valles Marineris, the largest canyon in the Solar System as seen by Mars Reconnaissance Orbiter spacecraft. In this region, hydrated sulfate salts have been detected.

  20. VizieR Online Data Catalog: LOFAR Bootes and 3C295 field sources (van Weeren+, 2014)

    NASA Astrophysics Data System (ADS)

    van Weeren, R. J.; Williams, W. L.; Tasse, C.; Rottgering, H. J. A.; Rafferty, D. A.; van der Tol, S.; Heald, G.; White, G. J.; Shulevski, A.; Best, P.; Intema, H. T.; Bhatnagar, S.; Reich, W.; Steinmetz, M.; van Velzen, S.; Ensslin, T. A.; Prandoni, I.; de Gasperin, F.; Jamrozy, M.; Brunetti, G.; Jarvis, M. J.; McKean, J. P.; Wise, M. W.; Ferrari, C.; Harwood, J.; Oonk, J. B. R.; Hoeft, M.; Kunert-Bajraszewska, M.; Horellou, C.; Wucknitz, O.; Bonafede, A.; Mohan, N. R.; Scaife, A. M. M.; Klockner, H.-R.; van Bemmel, I. M.; Merloni, A.; Chyzy, K. T.; Engels, D.; Falcke, H.; Pandey-Pommier, M.; Alexov, A.; Anderson, J.; Avruch, I. M.; Beck, R.; Bell, M. E.; Bentum, M. J.; Bernardi, G.; Breitling, F.; Broderick, J.; Brouw, W. N.; Bruggen, M.; Butcher, H. R.; Ciardi, B.; de Geus, E.; de Vos, M.; Deller, A.; Duscha, S.; Eisloffel, J.; Fallows, R. A.; Frieswijk, W.; Garrett, M. A.; Griessmeier, J.; Gunst, A. W.; Hamaker, J. P.; Hassall, T. E.; Horandel, J.; van der Horst, A.; Iacobelli, M.; Jackson, N. J.; Juette, E.; Kondratiev, V. I.; Kuniyoshi, M.; Maat, P.; Mann, G.; McKay-Bukowski, D.; Mevius, M.; Morganti, R.; Munk, H.; Offringa, A. R.; Orru, E.; Paas, H.; Pandey, V. N.; Pietka, G.; Pizzo, R.; Polatidis, A. G.; Renting, A.; Rowlinson, A.; Schwarz, D.; Serylak, M.; Sluman, J.; Smirnov, O.; Stappers, B. W.; Stewart, A.; Swinbank, J.; Tagger, M.; Tang, Y.; Thoudam, S.; Toribio, C.; Vermeulen, R.; Vocks, C.; Zarka, P.

    2017-04-01

    The Bootes and 3C 295 fields were simultaneously observed on 2012 April 12 as part of a multi-beam observation with the LOFAR LBA stations. The idea behind the multi-beam setup is that we use the 3C 295 observations as a calibrator field to transfer the gain amplitudes to the (target) Bootes field. The total integration time on both fields was 10.25 hr. Complete frequency coverage was obtained between 54 and 70 MHz for both fields, while non-contiguous frequency coverage was obtained between 30 and 54 MHz for the 3C 295 only. All four correlation products were recorded. By default, the frequency band was divided into sub-bands, each 195.3125 kHz wide. Each sub-band was further divided in 64 channels and the integration time was 1 s. (1 data file).

  1. Monoclonal Antibody Therapy and Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma

    ClinicalTrials.gov

    2013-01-08

    Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Waldenström Macroglobulinemia

  2. A Fosmid Cloning Strategy for Detecting the Widest Possible Spectrum of Microbes from the International Space Station Drinking Water System

    PubMed Central

    Choi, Sangdun; Chang, Mi Sook; Stuecker, Tara; Chung, Christine; Newcombe, David A.; Venkateswaran, Kasthuri

    2012-01-01

    In this study, fosmid cloning strategies were used to assess the microbial populations in water from the International Space Station (ISS) drinking water system (henceforth referred to as Prebiocide and Tank A water samples). The goals of this study were: to compare the sensitivity of the fosmid cloning strategy with that of traditional culture-based and 16S rRNA-based approaches and to detect the widest possible spectrum of microbial populations during the water purification process. Initially, microbes could not be cultivated, and conventional PCR failed to amplify 16S rDNA fragments from these low biomass samples. Therefore, randomly primed rolling-circle amplification was used to amplify any DNA that might be present in the samples, followed by size selection by using pulsed-field gel electrophoresis. The amplified high-molecular-weight DNA from both samples was cloned into fosmid vectors. Several hundred clones were randomly selected for sequencing, followed by Blastn/Blastx searches. Sequences encoding specific genes from Burkholderia, a species abundant in the soil and groundwater, were found in both samples. Bradyrhizobium and Mesorhizobium, which belong to rhizobia, a large community of nitrogen fixers often found in association with plant roots, were present in the Prebiocide samples. Ralstonia, which is prevalent in soils with a high heavy metal content, was detected in the Tank A samples. The detection of many unidentified sequences suggests the presence of potentially novel microbial fingerprints. The bacterial diversity detected in this pilot study using a fosmid vector approach was higher than that detected by conventional 16S rRNA gene sequencing. PMID:23346038

  3. A Search for Companions to Brown Dwarfs in the Taurus and Chamaeleon Star-Forming Regions

    NASA Astrophysics Data System (ADS)

    Todorov, K. O.; Luhman, K. L.; Konopacky, Q. M.; McLeod, K. K.; Apai, D.; Ghez, A. M.; Pascucci, I.; Robberto, M.

    2014-06-01

    We have used WFPC2 on board the Hubble Space Telescope to obtain images of 47 members of the Taurus and Chamaeleon I star-forming regions that have spectral types of M6-L0 (M ~ 0.01-0.1 M ⊙). An additional late-type member of Taurus, FU Tau (M7.25+M9.25), was also observed with adaptive optics at Keck Observatory. In these images, we have identified promising candidate companions to 2MASS J04414489+2301513 (ρ = 0.''105/15 AU), 2MASS J04221332+1934392 (ρ = 0.''05/7 AU), and ISO 217 (ρ = 0.''03/5 AU). We reported the first candidate in a previous study, showing that it has a similar proper motion as the primary in images from WFPC2 and Gemini adaptive optics. We have collected an additional epoch of data with Gemini that further supports that result. By combining our survey with previous high-resolution imaging in Taurus, Chamaeleon I, and Upper Sco (τ ~ 10 Myr), we measure binary fractions of 14/93 = 0.15^{+0.05}_{-0.03} for M4-M6 (M ~ 0.1-0.3 M ⊙) and 4/108 = 0.04^{+0.03}_{-0.01} for >M6 (M <~ 0.1 M ⊙) at separations of >10 AU. Given the youth and low density of these regions, the lower binary fraction at later types is probably primordial rather than due to dynamical interactions among association members. The widest low-mass binaries (>100 AU) also appear to be more common in Taurus and Chamaeleon I than in the field, which suggests that the widest low-mass binaries are disrupted by dynamical interactions at >10 Myr, or that field brown dwarfs have been born predominantly in denser clusters where wide systems are disrupted or inhibited from forming. Based on observations performed with the NASA/ESA Hubble Space Telescope, Gemini Observatory, and the W. M. Keck Observatory. The Hubble observations are associated with proposal IDs 11203, 11204, and 11983 and were obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

  4. Apparatus for detecting a magnetic anomaly contiguous to remote location by squid gradiometer and magnetometer systems

    DOEpatents

    Overton, Jr., William C.; Steyert, Jr., William A.

    1984-01-01

    A superconducting quantum interference device (SQUID) magnetic detection apparatus detects magnetic fields, signals, and anomalies at remote locations. Two remotely rotatable SQUID gradiometers may be housed in a cryogenic environment to search for and locate unambiguously magnetic anomalies. The SQUID magnetic detection apparatus can be used to determine the azimuth of a hydrofracture by first flooding the hydrofracture with a ferrofluid to create an artificial magnetic anomaly therein.

  5. Apparatus and method for detecting a magnetic anomaly contiguous to remote location by SQUID gradiometer and magnetometer systems

    DOEpatents

    Overton, W.C. Jr.; Steyert, W.A. Jr.

    1981-05-22

    A superconducting quantum interference device (SQUID) magnetic detection apparatus detects magnetic fields, signals, and anomalies at remote locations. Two remotely rotatable SQUID gradiometers may be housed in a cryogenic environment to search for and locate unambiguously magnetic anomalies. The SQUID magnetic detection apparatus can be used to determine the azimuth of a hydrofracture by first flooding the hydrofracture with a ferrofluid to create an artificial magnetic anomaly therein.

  6. Annual estimates of recharge, quick-flow runoff, and ET for the contiguous U.S. using empirical regression equations

    USGS Publications Warehouse

    Reitz, Meredith; Sanford, Ward E.; Senay, Gabriel; Cazenas, J.

    2017-01-01

    This study presents new data-driven, annual estimates of the division of precipitation into the recharge, quick-flow runoff, and evapotranspiration (ET) water budget components for 2000-2013 for the contiguous United States (CONUS). The algorithms used to produce these maps ensure water budget consistency over this broad spatial scale, with contributions from precipitation influx attributed to each component at 800 m resolution. The quick-flow runoff estimates for the contribution to the rapidly varying portion of the hydrograph are produced using data from 1,434 gaged watersheds, and depend on precipitation, soil saturated hydraulic conductivity, and surficial geology type. Evapotranspiration estimates are produced from a regression using water balance data from 679 gaged watersheds and depend on land cover, temperature, and precipitation. The quick-flow and ET estimates are combined to calculate recharge as the remainder of precipitation. The ET and recharge estimates are checked against independent field data, and the results show good agreement. Comparisons of recharge estimates with groundwater extraction data show that in 15% of the country, groundwater is being extracted at rates higher than the local recharge. These maps of the internally consistent water budget components of recharge, quick-flow runoff, and ET, being derived from and tested against data, are expected to provide reliable first-order estimates of these quantities across the CONUS, even where field measurements are sparse.

  7. Foreign Humanitarian Assistance

    DTIC Science & Technology

    2009-03-17

    based products and is adequate for the widest range of cultural or religious dietary restrictions. HDR will maintain the health of moderately...rehydration, fortified nutritional products, and micronutrient supplements; provide post- rape-care kits, including post-exposure prophylaxis for human

  8. Low-stress bicycling and network connectivity.

    DOT National Transportation Integrated Search

    2012-05-01

    For a bicycling network to attract the widest possible segment of the population, its most fundamental attribute should be low-stress connectivity, that is, providing routes between peoples origins and destinations that do not require cyclists to ...

  9. A Valentine from Vesta

    NASA Image and Video Library

    2012-02-14

    This image from NASA Dawn spacecraft, is based on a framing camera image that is overlain by a color-coded height representation of topography. This heart-shaped hollow is roughly 10 kilometers 6 miles across at its widest point.

  10. Public Participation Guide: Press and Media

    EPA Pesticide Factsheets

    In general, news or media releases are used to disseminate information. Media releases aim to get the widest possible coverage for a community issue or proposal through the publication or broadcasting of the information in the release.

  11. Viscous constitutive relations of solid-liquid composites in terms of grain boundary contiguity: 1. Grain boundary diffusion control model

    NASA Astrophysics Data System (ADS)

    Takei, Yasuko; Holtzman, Benjamin K.

    2009-06-01

    Viscous constitutive relations of partially molten rocks deforming in the regime of grain boundary (GB) diffusion creep are derived theoretically on the basis of microstructural processes at the grain scale. The viscous constitutive relation developed in this study is based on contiguity as an internal state variable, which enables us to take into account the detailed effects of grain-scale melt distribution observed in experiments. Compared to the elasticities derived previously for the same microstructural model, the viscosities are much more sensitive to the presence of melt and variations in contiguity. As explored in this series of three companion papers, this "contiguity" model predicts that a very small amount of melt (ϕ < 0.01) significantly reduces the bulk and shear viscosities. Furthermore, a large anisotropy in viscosity is produced by anisotropy in contiguity, which occurs in deforming partially molten rocks. These results have important implications for deformation and melt extraction at small melt fractions, as well as for shear-induced melt segregation. The viscous and elastic constitutive relations derived in terms of contiguity bridge microscopic grain-scale and macroscopic continuum properties. These constitutive relations are essential for investigating melt migration dynamics in a forward sense on the basis of the basic equations of two-phase dynamics and in an inverse sense on the basis of seismological observations.

  12. Current applications of human pluripotent stem cells: possibilities and challenges.

    PubMed

    Ho, Pai-Jiun; Yen, Men-Luh; Yet, Shaw-Fang; Yen, B Linju

    2012-01-01

    Stem cells are self-renewable cells with the differentiation capacity to develop into somatic cells with biological functions. This ability to sustain a renewable source of multi- and/or pluripotential differentiation has brought new hope to the field of regenerative medicine in terms of cell therapy and tissue engineering. Moreover, stem cells are invaluable tools as in vitro models for studying diverse fields, from basic scientific questions such as developmental processes and lineage commitment, to practical application including drug screening and testing. The stem cells with widest differentiation potential are pluripotent stem cells (PSCs), which are rare cells with the ability to generate somatic cells from all three germ layers. PSCs are considered the most optimal choice for therapeutic potential of stem cells, bringing new impetus to the field of regenerative medicine. In this article, we discuss the therapeutic potential of human PSCs (hPSCs) including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), reviewing the current preclinical and clinical data using these stem cells. We describe the classification of different sources of hPSCs, ongoing research, and currently encountered clinical obstacles of these novel and versatile human stem cells.

  13. Optical And Near-infrared Variability Among Distant Galactic Nuclei Of The CANDELS EGS Field

    NASA Astrophysics Data System (ADS)

    Grogin, Norman A.; Dahlen, T.; Donley, J.; Koekemoer, A. M.; Salvato, M.; CANDELS Collaboration

    2014-01-01

    The CANDELS HST Multi-cycle Treasury Program completed its observations of the EGS field in May 2013. The coverage comprises WFC3/IR exposures in J-band and H-band across a contiguous 200 square arcminutes, and coordinated parallel ACS/WFC exposures in V-band and I-band across a contiguous 270 square arcminutes that largely overlaps the WFC3/IR coverage. These observations were split between two epochs with 52-day spacing for the primary purpose of high-redshift supernovae (SNe) detection and follow-up. However, this combination of sensitivity, high resolution, and time spacing is also well-suited to detect optical and near-infrared variability ("ONIV") among moderate- to high-redshift galaxy nuclei (H<25AB mag; I<26AB mag). These data are sensitive to rest-frame variability time-scales of up to several weeks, and in combination with the original EGS ACS imaging from 2004, to time-scales of up to several years in the V- and I-bands. The overwhelming majority of these variable galaxy nuclei will be AGN; the small fraction arising from SNe have already been meticulously culled by the CANDELS high-redshift SNe search effort. These ONIV galaxy nuclei potentially represent a significant addition to the census of distant lower-luminosity AGN subject to multi-wavelength scrutiny with CANDELS. We present the preliminary results of our EGS variability analysis, including a comparison of the HST ONIVs with the known AGN candidates in the field from deep Spitzer and Chandra imaging, and from extensive ground-based optical spectroscopy as well as HST IR-grism spectroscopy. We also assess the redshift distribution of the ONIVs from both spectroscopy and from robust SED-fitting incorporating ancillary deep ground-based imaging along with the CANDELS VIJH photometry. We compare these results with our prior variability analysis of the similarly-observed CANDELS UDS field from 2011 and CANDELS COSMOS field from 2012.

  14. Bortezomib and Filgrastim in Promoting Stem Cell Mobilization in Patients With Non-Hodgkin Lymphoma or Multiple Myeloma Undergoing Stem Cell Transplant

    ClinicalTrials.gov

    2017-05-23

    Adult Grade III Lymphomatoid Granulomatosis; B-cell Chronic Lymphocytic Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Progressive Hairy Cell Leukemia, Initial Treatment; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Small Lymphocytic Lymphoma; Stage II Multiple Myeloma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Untreated Hairy Cell Leukemia; Waldenström Macroglobulinemia

  15. Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas

    ClinicalTrials.gov

    2017-09-28

    Adult Grade III Lymphomatoid Granulomatosis; B-cell Chronic Lymphocytic Leukemia; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Progressive Hairy Cell Leukemia, Initial Treatment; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage 0 Chronic Lymphocytic Leukemia; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Small Lymphocytic Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Testicular Lymphoma; Untreated Hairy Cell Leukemia; Waldenström Macroglobulinemia

  16. 76 FR 15281 - Agency Information Collection Activities: Proposed Collection; Comment Request-Evaluation of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... periods. The questions posed in the study will help FNS better understand purchasing decisions and will... nutrition information needed for purchasing the widest variety of healthful foods, menu planning and...

  17. The widest practicable dissemination: The NASA technical report server

    NASA Technical Reports Server (NTRS)

    Nelson, Michael L.; Gottlich, Gretchen L.; Bianco, David J.; Binkley, Robert L.; Kellogg, Yvonne D.; Paulson, Sharon S.; Beaumont, Chris J.; Schmunk, Robert B.; Kurtz, Michael; Accomazzi, Alberto

    1995-01-01

    The search for innovative methods to distribute NASA's information lead a gross-roots team to create the NASA Technical Report Server (NTRS), which uses the World Wide Web and other popular Internet-based information systems as search engines. The NTRS is an inter-center effort which provides uniform access to various distributed publication servers residing on the Internet. Users have immediate desktop access to technical publications from NASA centers and institutes. This paper presents the NTRS architecture, usage metrics, and the lessons learned while implementing and maintaining the services over the initial 6-month period. The NTRS is largely constructed with freely available software running on existing hardware. NTRS builds upon existing hardware and software, and the resulting additional exposure for the body of literature contained will allow NASA to ensure that its institutional knowledge base will continue to receive the widest practicable and appropriate dissemination.

  18. [Book review] Birds of Malheur National Wildlife Refuge, Oregon

    USGS Publications Warehouse

    Browning, M. Ralph

    1991-01-01

    Although John Warham has worked for at least 40 years on procellariids, this book is much more than just a summary of a distinguished research career. It is a useful synthesis of the vast and often obscure literature on the more than 100 species of shearwaters, petrels, albatrosses, and fulmars that comprise the avian order with the widest range of body mass (19.5 g to 8.7 kg) and widest distribution, throughout the world's oceans, from the tropics to open leads in polar ice packs. The order's literary credentials are also impressive, with contributions from Dionysus (200 AD), St. Augustine, and Cole- ridge (not cited). Warham has also unearthed useful references from journals not examined by many ornithologists, such as Bocagiana, Il-Merill, and the Journal of the Manx Museum. He also appears to have done a good job of covering the Japanese-language literature.

  19. Issues in visual support to real-time space system simulation solved in the Systems Engineering Simulator

    NASA Technical Reports Server (NTRS)

    Yuen, Vincent K.

    1989-01-01

    The Systems Engineering Simulator has addressed the major issues in providing visual data to its real-time man-in-the-loop simulations. Out-the-window views and CCTV views are provided by three scene systems to give the astronauts their real-world views. To expand the window coverage for the Space Station Freedom workstation a rotating optics system is used to provide the widest field of view possible. To provide video signals to as many viewpoints as possible, windows and CCTVs, with a limited amount of hardware, a video distribution system has been developed to time-share the video channels among viewpoints at the selection of the simulation users. These solutions have provided the visual simulation facility for real-time man-in-the-loop simulations for the NASA space program.

  20. Propagation and Evolution of CMEs in the Interplanetary Medium: Analysis of Remote Sensing and In situ Observations

    NASA Technical Reports Server (NTRS)

    Figueroa-Vinas, Adolfo; Nieves-Chinchilla, Teresa; Vourlidas, Angelos; Gomez-Herrero, Raul; Malandraki, Olga; Szabo, Adam; Dresing, Nina; Davila, Joseph M.

    2010-01-01

    EUV disk imagers and white light coronagraphs have provided for many years information on the early formation and evolution of corona) mass ejections (CMEs). More recently, the novel heliospheric imaging instruments aboard the STEREO mission are providing crucial remote sensing information on the interplanetary evolution of these events while in situ instruments complete the overall characterization of the interplanetary CMEs. In this work, we present an analysis of CMEs from the Sun to the interplanetary medium using combined data from THE SOHO, STEREO, WIND, and ACE spacecraft. The events were selected to cover the widest possible spectrum of different ambient solar wind, magnetic field configurations, plasma parameters, etc. to allow uncovering those aspects that are important in understanding the propagation and evolution mechanisms of CMEs in the interplanetary medium.

  1. Detection of a stellar flare at extreme ultraviolet wavelengths

    NASA Technical Reports Server (NTRS)

    Barstow, M. A.; Denby, M.; Pye, J. P.; Pankiewicz, G. S.; Bromage, G. E.; Gonzalez-Riestra, R.

    1991-01-01

    During the all-sky survey conducted by the Rosat Wide Field Camera, the binary flare star system BY Draconis was monitored with coverage by the IUE satellite far-UV and optical observations and by the Rosat X-ray telescope for part of the time. A stellar flare was detected in all four wavebands. This is the first unambiguous EUV detection of a flare and one of the widest simultaneous wavelength-range coverages obtained. The peak luminosity and total energy of this flare in the photon energy range 0.08-0.18 keV are comparable with the values obtained for a number of flares integrated over a larger energy range by Exosat satellite observations in 1983-86. It is concluded that radiation in the EUV carries away a substantial fraction of the total flare energy.

  2. Laser Beam Melting of Alumina: Effect of Absorber Additions

    NASA Astrophysics Data System (ADS)

    Moniz, Liliana; Colin, Christophe; Bartout, Jean-Dominique; Terki, Karim; Berger, Marie-Hélène

    2018-03-01

    Ceramic laser beam melting offers new manufacturing possibilities for complex refractory structures. Poor absorptivity in near infra-red wavelengths of oxide ceramics is overcome with absorber addition to ceramic powders. Absorbers affect powder bed densities and geometrical stability of melted tracks. Optimum absorber content is defined for Al2O3 by minimizing powder bed porosity, maximizing melting pool geometrical stability and limiting shrinkage. Widest stability fields are obtained with addition of 0.1 wt.% C and 0.5 wt.% β-SiC. Absorption coefficient values of Beer-Lambert law follow stability trends: they increase with C additions, whereas with β-SiC, a maximum is reached for 0.5 wt.%. Powder particle ejections are also identified. Compared to metallic materials, this ejection phenomenon can no longer be neglected when establishing a three-dimensional manufacturing strategy.

  3. Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure

    DOEpatents

    Tang, Keqi [Richland, WA; Shvartsburg, Alexandre A [Richland, WA; Smith, Richard D [Richland, WA

    2008-03-04

    The invention discloses a new interface with non-circular conductance limit aperture(s) useful for effective transmission of non-circular ion beams between stages with different gas pressure. In particular, the invention provides an improved coupling of field asymmetric waveform ion mobility spectrometry (FAIMS) analyzers of planar or side-to-side geometry to downstream stages such as mass spectrometry or ion mobility spectrometry. In this case, the non-circular aperture is rectangular; other geometries may be optimum in other applications. In the preferred embodiment, the non-circular aperture interface is followed by an electrodynamic ion funnel that may focus wide ion beams of any shape into tight circular beams with virtually no losses. The jet disrupter element of the funnel may also have a non-circular geometry, matching the shape of arriving ion beam. The improved sensitivity of planar FAIMS/MS has been demonstrated in experiments using a non-contiguous elongated aperture but other embodiments (e.g., with a contiguous slit aperture) may be preferable, especially in conjunction with an ion funnel operated at high pressures.

  4. 33 CFR 2.28 - Contiguous zone.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... from the territorial sea baseline. (b) For all other purposes, contiguous zone means all waters within... nautical miles from the territorial sea baseline, but in no case extending within the territorial sea of...

  5. ADX: A high Power Density, Advanced RF-Driven Divertor Test Tokamak for PMI studies

    NASA Astrophysics Data System (ADS)

    Whyte, Dennis; ADX Team

    2015-11-01

    The MIT PSFC and collaborators are proposing an advanced divertor experiment, ADX; a divertor test tokamak dedicated to address critical gaps in plasma-material interactions (PMI) science, and the world fusion research program, on the pathway to FNSF/DEMO. Basic ADX design features are motivated and discussed. In order to assess the widest range of advanced divertor concepts, a large fraction (>50%) of the toroidal field volume is purpose-built with innovative magnetic topology control and flexibility for assessing different surfaces, including liquids. ADX features high B-field (>6 Tesla) and high global power density (P/S ~ 1.5 MW/m2) in order to access the full range of parallel heat flux and divertor plasma pressures foreseen for reactors, while simultaneously assessing the effect of highly dissipative divertors on core plasma/pedestal. Various options for efficiently achieving high field are being assessed including the use of Alcator technology (cryogenic cooled copper) and high-temperature superconductors. The experimental platform would also explore advanced lower hybrid current drive and ion-cyclotron range of frequency actuators located at the high-field side; a location which is predicted to greatly reduce the PMI effects on the launcher while minimally perturbing the core plasma. The synergistic effects of high-field launchers with high total B on current and flow drive can thus be studied in reactor-relevant boundary plasmas.

  6. Electric power supply and demand for the contiguous United States, 1981 - 1990

    NASA Astrophysics Data System (ADS)

    1981-07-01

    The outlook for electric power supply and demand in the United States decade 1981 to 1990 is reviewed from the perspective of reliability and adequacy of service. Electric power supply adequacy as projected for the nine Regional Reliability Council areas of the contiguous United States is reported as well as interruptible load data reported by the Councils. cogeneration is discussed. Each of the 27 electric regions (sub-areas of the nine Council areas) in the contiguous US are studied. A glossary of terms is given. Appendices describe the Council structure, and include a copy of the ERA-411 Manual, which contains all the items to which the Councils were asked to respond. The utilities with included data, the Staff Report, Estimated Electric Demand and Supply for Summer 1981, Contiguous United States dated May 1981 are included.

  7. System and method for non-destructive evaluation of surface characteristics of a magnetic material

    DOEpatents

    Jiles, David C.; Sipahi, Levent B.

    1994-05-17

    A system and a related method for non-destructive evaluation of the surface characteristics of a magnetic material. The sample is excited by an alternating magnetic field. The field frequency, amplitude and offset are controlled according to a predetermined protocol. The Barkhausen response of the sample is detected for the various fields and offsets and is analyzed. The system produces information relating to the frequency content, the amplitude content, the average or RMS energy content, as well as count rate information, for each of the Barkhausen responses at each of the excitation levels applied during the protocol. That information provides a contiguous body of data, heretofore unavailable, which can be analyzed to deduce information about the surface characteristics of the material at various depths below the surface.

  8. Identification and comprehension of symbolic exit signs for small transport-category airplanes.

    DOT National Transportation Integrated Search

    2014-02-01

    Global growth in travel has resulted in the need to standardize safety information and guidance systems : for communication of significant information to the widest audience possible. Through uniform design and : common visual components, persons in ...

  9. Ku-band multiple beam antenna

    NASA Technical Reports Server (NTRS)

    Chen, C. C.; Franklin, C. F.

    1980-01-01

    The frequency reuse capability is demonstrated for a Ku-band multiple beam antenna which provides contiguous low sidelobe spot beams for point-to-point communications between any two points within the continental United States (CONUS), or regional coverage beams for direct broadcast systems. A spot beam antenna in the 14/21 GHz band which provides contiguous overlapping beams covering CONUS and two discrete beams covering Hawaii and Alaska were designed, developed, and tested. Two reflector antennas are required for providing contiguous coverage of CONUS. Each is comprised of one offset parabolic reflector, one flat polarization diplexer, and two separate planar array feeds. This antenna system provides contiguous spot beam coverage of CONUS, utilizing 15 beams. Also designed, developed and demonstrated was a shaped contoured beam antenna system which provides contiguous four time zone coverage of CONUS from a single offset parabolic reflector incorporating one flat polarization diplexer and two separate planar array feeds. The beams which illuminate the eastern time zone and the mountain time zone are horizontally polarized, while the beams which illuminate the central time zone and the pacific time zone are vertically polarized. Frequency reuse is achieved by amplitude and polarization isolation.

  10. Pegfilgrastim and Rituximab in Treating Patients With Untreated, Relapsed, or Refractory Follicular Lymphoma, Small Lymphocytic Lymphoma, or Marginal Zone Lymphoma

    ClinicalTrials.gov

    2017-09-08

    Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma

  11. Fundus photography with a smartphone in indirect ophthalmoscopy in dogs and cats.

    PubMed

    Kanemaki, Nobuyuki; Inaniwa, Mizuho; Terakado, Kunihiko; Kawarai, Shinpei; Ichikawa, Yoichiro

    2017-05-01

    To introduce a simple method for fundus photography of dogs and cats using a smartphone and indirect ophthalmoscopy lenses. Fundus photographs of dogs and cats with transparent ocular media were obtained with 15D, 20D, 28D, and 40D indirect lenses and an iPhone-6, in a dark room and after pharmacologic pupil dilation. The photographs were recorded as still images using a video application and a video-to-still image application. Two types of neutral density (ND) filters were used as required for reduction of the torch illumination power of the iPhone. The images obtained in this study were upside-down as a result of the optics used. A 180-degree rotation was used to show their natural anatomical orientation. The image field of view varied with the diopter strength of the indirect lens used. The 40-diopter lens offered the widest field. Still images obtained with a smartphone, and indirect lenses may be useful for client communication and teaching in small animal ophthalmology. © 2016 American College of Veterinary Ophthalmologists.

  12. LSPM J1314+1320: An Oversized Magnetic Star with Constraints on the Radio Emission Mechanism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MacDonald, James; Mullan, D. J.

    LSPM J1314+1320 (=NLTT 33370) is a binary star system consisting of two nearly identical pre-main-sequence stars of spectral type M7. The system is remarkable among ultracool dwarfs for being the most luminous radio emitter over the widest frequency range. Masses and luminosities are at first sight consistent with the system being coeval at age ∼80 Myr according to standard (nonmagnetic) evolutionary models. However, these models predict an average effective temperature of ∼2950 K, which is 180 K hotter than the empirical value. Thus, the empirical radii are oversized relative to the standard models by ≈13%. We demonstrate that magnetic stellarmore » models can quantitatively account for the oversizing. As a check on our models, we note that the radio emission limits the surface magnetic field strengths: the limits depend on identifying the radio emission mechanism. We find that the field strengths required by our magnetic models are too strong to be consistent with gyrosynchrotron emission but are consistent with electron cyclotron maser emission.« less

  13. Improving Translation Models for Predicting the Energy Yield of Photovoltaic Power Systems. Cooperative Research and Development Final Report, CRADA Number CRD-13-526

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Emery, Keith

    2015-08-04

    The project under this CRADA will analyze field data of various flat-plate and concentrator module technologies and cell measurements at the laboratory level. The field data will consist of current versus voltage data collected over many years on a latitude tilt test bed for Si, CdTe, amorphous silicon, and CIGS technologies. The concentrator data will be for mirror- and lens-based module designs using multijunction cells. The laboratory data will come from new measurements of cell performance with systematic variation of irradiance, temperature and spectral composition. These measurements will be labor-intensive and the aim will be to cover the widest possiblemore » parameter space for as many different PV samples as possible. The data analysis will require software tools to be developed. These tools will be customized for use with the specific NREL datasets and will be unsuitable for commercial release. The tools will be used to evaluate different translation equations against NREL outdoor datasets.« less

  14. Medical Entomology Studies - XVI. A Review of the Species of Subgenus Verrallina, Genus Aedes, from Sri Lanka and a Revised Description of the Subgenus (Diptera: Culicidae)

    DTIC Science & Technology

    1984-01-01

    into several lightly pigmented flattened contiguous leaf -like structures; gonostylus attached to apex of gonocoxite (Ae. quudrispinutus King and...contiguous leaf -like structures or a single short broad plate; gonostylus attached to apex of gonocoxite. Pupa. Trumpet as for Series I; bases of setae 2, 4...0.4-O. 5 produced into several lightly pigmented flattened contiguous leaf -like structures with apices fused into a single flattened plate which is

  15. Impact of Expanded North Slope of Alaska Crude Oil Production on Crude Oil Flows in the Contiguous United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeRosa, Sean E.; Flanagan, Tatiana Paz

    The National Transportation Fuels Model was used to simulate a hypothetical increase in North Slope of Alaska crude oil production. The results show that the magnitude of production utilized depends in part on the ability of crude oil and refined products infrastructure in the contiguous United States to absorb and adjust to the additional supply. Decisions about expanding North Slope production can use the National Transportation Fuels Model take into account the effects on crude oil flows in the contiguous United States.

  16. 50 CFR 648.51 - Gear and crew restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... possession on board such vessels shall not exceed 31 ft (9.4 m) measured at the widest point in the bail of... the dredge bottom. No more than triple linking shall be used in or on the dredge bottom portion and...

  17. Method and program product for determining a radiance field in an optical environment

    NASA Technical Reports Server (NTRS)

    Reinersman, Phillip N. (Inventor); Carder, Kendall L. (Inventor)

    2007-01-01

    A hybrid method is presented by which Monte Carlo techniques are combined with iterative relaxation techniques to solve the Radiative Transfer Equation in arbitrary one-, two- or three-dimensional optical environments. The optical environments are first divided into contiguous regions, or elements, with Monte Carlo techniques then being employed to determine the optical response function of each type of element. The elements are combined, and the iterative relaxation techniques are used to determine simultaneously the radiance field on the boundary and throughout the interior of the modeled environment. This hybrid model is capable of providing estimates of the under-water light field needed to expedite inspection of ship hulls and port facilities. It is also capable of providing estimates of the subaerial light field for structured, absorbing or non-absorbing environments such as shadows of mountain ranges within and without absorption spectral bands such as water vapor or CO.sub.2 bands.

  18. Redshift Survey Strategies

    NASA Astrophysics Data System (ADS)

    Jones, A. W.; Bland-Hawthorn, J.; Kaiser, N.

    1994-12-01

    In the first half of 1995, the Anglo-Australian Observatory is due to commission a wide field (2.1(deg) ), 400-fiber, double spectrograph system (2dF) at the f/3.3 prime focus of the AAT 3.9m bi-national facility. The instrument should be able to measure ~ 4000 galaxy redshifts (assuming a magnitude limit of b_J ~\\ 20) in a single dark night and is therefore ideally suited to studies of large-scale structure. We have carried out simple 3D numerical simulations to judge the relative merits of sparse surveys and contiguous surveys. We generate a survey volume and fill it randomly with particles according to a selection function which mimics a magnitude-limited survey at b_J = 19.7. Each of the particles is perturbed by a gaussian random field according to the dimensionless power spectrum k(3) P(k) / 2pi (2) determined by Feldman, Kaiser & Peacock (1994) from the IRAS QDOT survey. We introduce some redshift-space distortion as described by Kaiser (1987), a `thermal' component measured from pairwise velocities (Davis & Peebles 1983), and `fingers of god' due to rich clusters at random density enhancements. Our particular concern is to understand how the window function W(2(k)) of the survey geometry compromises the accuracy of statistical measures [e.g., P(k), xi (r), xi (r_sigma ,r_pi )] commonly used in the study of large-scale structure. We also examine the reliability of various tools (e.g. genus) for describing the topological structure within a contiguous region of the survey.

  19. Coal dust contiguity-induced changes in the concentration of TNF- and NF- B p65 on the ocular surface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Z.Y.; Hong, J.; Liu, Z.Y.

    2009-07-01

    To observe the influence of coal dust on ocular surface of coal miners and rabbits with coal dust contiguity on expression TNF- and NF- Bp65 and dry eye occurrence. Expression TNF- and NF- Bp65 in ocular surface were determined. Results showed tear production, BUT and lysozyme decreased for coal miners and rabbits with coal dust contiguity. Coal dust exposure was linked to development of xerophthalmia, and induced a higher expression of NF- B p65 and TNF- perhaps as a mechanism to resist coal dust ocular surface injury.

  20. Contiguity and Entire Separability of States on von Neumann Algebras

    NASA Astrophysics Data System (ADS)

    Haliullin, Samigulla

    2017-12-01

    We introduce the notions of the contiguity and entirely separability for two sequences of states on von Neumann algebras. The ultraproducts technique allows us to reduce the study of the contiguity to investigation of the equivalence for two states. Here we apply the Ocneanu ultraproduct and the Groh-Raynaud ultraproduct (see Ocneanu (1985), Groh (J. Operator Theory, 11, 2, 395-404 1984), Raynaud (J. Operator Theory, 48, 1, 41-68, 2002), Ando and Haagerup (J. Funct. Anal., 266, 12, 6842-6913, 2014)), as well as the technique developed in Mushtari and Haliullin (Lobachevskii J. Math., 35, 2, 138-146, 2014).

  1. Lake shoreline in the contiguous United States: Quantity, distribution and sensitivity to observation resolution

    USGS Publications Warehouse

    Winslow, Luke A.; Read, Jordan S.; Hanson, Paul C.; Stanley, Emily H.

    2013-01-01

    1. Quantifying lake biogeochemical processing at broad spatial scales requires that we scale processes along with physical metrics. Past work has primarily scaled lentic processes using estimates of lake surface area. However, many processes important to lakes, such as material, energy and biological fluxes and biogeochemical cycling, scale with lake perimeter. 2. We estimate the total lake perimeter for the contiguous United States (U.S.) and examine the sensitivity of this estimate to measurement resolution. At the original mapping resolution, lakes in the contiguous U.S. have a total perimeter of over 1.8 million km. 3. The change in measured perimeter versus measurement resolution for the contiguous U.S. had a log-log slope (also known as the fractal dimension) of 0.21, generally less than previously reported estimates. With changing observation resolution, total measured perimeter was most sensitive to the inclusion or exclusion of small lakes, not shoreline complexity. 4. The total aquatic–terrestrial interface in lakes is less than one-tenth that of streams and rivers, which collectively account for over 21 million km of shoreline in the contiguous U.S. This study further describes the distribution of lake perimeter and proposes a technique that can contribute to understanding continental-scale processes.

  2. Rubber industry

    NASA Astrophysics Data System (ADS)

    Staszak, Maciej

    2018-03-01

    Following chapter presents short introductory description of rubber and rubber industry. The main problem of rubber industry is the way of the usage of spent tires. Furthermore very important group of problems arise considering the metal and nonmetal additives which are significant component of the vulcanized rubber. The key attention is dedicated to typical ways of rubber usage in utilization and recovery of metals from spent rubber materials concentrating specifically on used tires processing. The method of recovery of rare metals from rubber tires was described. The rubber debris finds widest use in the field of waste metal solutions processing. The environmental pollution caused by metals poses serious threat to humans. Several applications of the use of waste rubber debris to remove metals from environmental waters were described. Moreover, the agriculture usage of waste tire rubber debris is described, presenting systems where the rubber material can be useful as a soil replacement.

  3. Predictability of lesion durability for AF ablation using phased radiofrequency: Power, temperature, and duration impact creation of transmural lesions.

    PubMed

    Hocini, Mélèze; Condie, Cathy; Stewart, Mark T; Kirchhof, Nicole; Foell, Jason D

    2016-07-01

    Long-term clinical outcomes for atrial fibrillation ablation depend on the creation of durable transmural lesions during pulmonary vein isolation and on substrate modification. Focal conventional radiofrequency (RF) ablation studies have demonstrated that tissue temperature and power are important factors for lesion formation. However, the impact and predictability of temperature and power on contiguous, transmural lesion formation with a phased RF system has not been described. The purpose of this study was to determine the sensitivity, specificity, and predictability of power and temperature to create contiguous, transmural lesions with the temperature-controlled, multielectrode phased RF PVAC GOLD catheter. Single ablations with the PVAC GOLD catheter were performed in the superior vena cava of 22 pigs. Ablations from 198 PVAC GOLD electrodes were evaluated by gross examination and histopathology for lesion transmurality and contiguity. Lesions were compared to temperature and power data from the phased RF GENius generator. Effective contact was defined as electrodes with a temperature of ≥50°C and a power of ≥3 W. Eighty-five percent (168 of 198) of the lesions were transmural and 79% (106 of 134) were contiguous. Electrode analysis showed that >30 seconds of effective contact identified transmural lesions with 85% sensitivity (95% confidence interval [CI] 78%-89%), 93% specificity (95% CI 76%-99%), and 99% positive predictive value (95% CI 94%-100%). Sensitivity for lesion contiguity was 95% (95% CI 89%-98%), with 62% specificity (95% CI 42%-78%) and 90% positive predictive value (95% CI 83%-95%). No char or coagulum was observed on the catheter or tissue. PVAC GOLD safely, effectively, and predictably creates transmural and contiguous lesions. Copyright © 2016 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  4. Charles Darwin and the evolution of human grammatical systems.

    PubMed

    Buckingham, Hugh W; Christman, Sarah S

    2010-04-08

    Charles Darwin's evolutionary theories of animal communication were deeply embedded in a centuries-old model of association psychology, whose prodromes have most often been traced to the writings of Aristotle. His notions of frequency of occurrence of pairings have been passed down through the centuries and were a major ontological feature in the formation of associative connectivity. He focused on the associations of cause and effect, contiguity of sequential occurrence, and similarity among items. Cause and effect were often reduced to another type of contiguity relation, so that Aristotle is most often evoked as the originator of the associative bondings through similarity and contiguity, contiguity being the most powerful and frequent means of association. Contiguity eventually became the overriding mechanism for serial ordering of mental events in both perception and action. The notions of concatenation throughout the association psychology took the form of "trains" of events, both sensory and motor, in such a way that serial ordering came to be viewed as an item-by-item string of locally contiguous events. Modern developments in the mathematics of serial ordering have advanced in sophistication since the early and middle twentieth century, and new computational methods have allowed us to reevaluate the serial concatenative theories of Darwin and the associationists. These new models of serial order permit a closer comparative scrutiny between human and nonhuman. The present study considers Darwin's insistence on a "degree" continuity between human and nonhuman animal serial ordering. We will consider a study of starling birdsongs and whether the serial ordering of those songs provides evidence that they have a syntax that at best differs only in degree and not in kind with the computations of human grammatical structures. We will argue that they, in fact, show no such thing.

  5. 45 CFR 1211.1-4 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-4 Policy. It is ACTION's policy to provide volunteers the widest latitude to.... This regulation is designed to assure that the rights of individual volunteers are recognized and to...

  6. 45 CFR 1211.1-4 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-4 Policy. It is ACTION's policy to provide volunteers the widest latitude to.... This regulation is designed to assure that the rights of individual volunteers are recognized and to...

  7. A Library in Your Palm.

    ERIC Educational Resources Information Center

    Fox, Megan K.

    2003-01-01

    Examines how librarians are customizing their services and collections for handheld computing. Discusses the widest adoption of PDAs (personal digital assistants) in libraries that serve health and medical communities; PDA-friendly information pages; the reference focus; journals and databases; lending materials; publicity; use of PDAs by library…

  8. 7 CFR 1735.11 - Area coverage.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 11 2013-01-01 2013-01-01 false Area coverage. 1735.11 Section 1735.11 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE... Policies § 1735.11 Area coverage. Borrowers must make adequate telephone service available to the widest...

  9. Amylase production potentials of bacterial isolates obtained from the gut of Oryctes rhinoceros larvae

    NASA Astrophysics Data System (ADS)

    Aryati, P. C.; Pangastuti, A.; Sari, S. L. A.

    2017-04-01

    Amylase is one of the main enzymes used in industry, such as food, detergent, textile, and pharmaceutical industry. Amylase can be produced by plants, animals, and microorganisms. However, bacterial and fungal amylases have dominated application in industries. This research was aimed to determine amylolytic activity of bacteria isolated from the gut of Oryctes rhinoceros larvae. Based on clear zone formation, 9 from 11 isolates showed amylolytic activity. Isolates with the widest clear zone, i.e Bacillus subtilis GOR1, Bacillus cereus GOR3, and Bacillus pumilus GOR2, were screened for amylolytic activity based on reduction sugar production. The result showed that Bacillus subtilis GOR1 was the most potential as amylase producer, showed by the widest clear zone 5.224 cm2 and highest reduction sugar production 0.0235 mg/ml. Highest amylase specific activity (0.1447 U/mg protein) was obtained at 60°C and pH 7. Amylase activity was stable for 3 hours at 60°C with residual activity respectively was 59.7%.

  10. Optical synthesizer for a large quadrant-array CCD camera: Center director's discretionary fund

    NASA Technical Reports Server (NTRS)

    Hagyard, Mona J.

    1992-01-01

    The objective of this program was to design and develop an optical device, an optical synthesizer, that focuses four contiguous quadrants of a solar image on four spatially separated CCD arrays that are part of a unique CCD camera system. This camera and the optical synthesizer will be part of the new NASA-Marshall Experimental Vector Magnetograph, and instrument developed to measure the Sun's magnetic field as accurately as present technology allows. The tasks undertaken in the program are outlined and the final detailed optical design is presented.

  11. 16th iWoRiD scientific summary and personal impressions

    NASA Astrophysics Data System (ADS)

    Vacchi, Andrea

    2015-08-01

    The development of Radiation Imaging Detectors dedicated to specific front edge use is a rapidly expanding galaxy taking force from a healthy mixture of growing ambitions within basic science targets and applicative use in many contiguous fields. The growth of the high technology imaging tools market is a relevant motivating element. On the scene of this conference a flow of very accurate and informative presentations has allowed to gather a vivid image on the almost frantic target oriented work, the results shown have often surpassed the most visionary expectations.

  12. Extemporaneous transposition flap for closing two contiguous surgical excision.

    PubMed

    Boggio, Paolo; Veronese, Federica; Miglino, Benedetta; Graziola, Francesca; Tiberio, Rossana; Colombo, Enrico

    2018-08-01

    The authors present a surgical procedure to remove two contiguous cutaneous lesions using a single transposition flap and suture line without an evident scar. This method is useful when rhomboid surgical exeresis could not represent the best choice to obtain an optimum aesthetic result.

  13. 48 CFR 242.1402 - Volume movements within the contiguous United States.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Volume movements within the contiguous United States. 242.1402 Section 242.1402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT...

  14. VizieR Online Data Catalog: PHAT X. UV-IR photometry of M31 stars (Williams+, 2014)

    NASA Astrophysics Data System (ADS)

    Williams, B. F.; Lang, D.; Dalcanton, J. J.; Dolphin, A. E.; Weisz, D. R.; Bell, E. F.; Bianchi, L.; Byler, N.; Gilbert, K. M.; Girardi, L.; Gordon, K.; Gregersen, D.; Johnson, L. C.; Kalirai, J.; Lauer, T. R.; Monachesi, A.; Rosenfield, P.; Seth, A.; Skillman, E.

    2015-01-01

    The data for the Panchromatic Hubble Andromeda Treasury (PHAT) survey were obtained from 2010 July 12 to 2013 October 12 using the Advanced Camera for Surveys (ACS) Wide Field Channel (WFC), the Wide Field Camera 3 (WFC3) IR (infrared) channel, and the WFC3 UVIS (ultraviolet-optical) channel. The observing strategy is described in detail in Dalcanton et al. (2012ApJS..200...18D). A list of the target names, observing dates, coordinates, orientations, instruments, exposure times, and filters is given in Table 1. Using the ACS and WFC3 cameras aboard HST, we have photometered 414 contiguous WFC3/IR footprints covering 0.5deg2 of the M31 star-forming disk. (4 data files).

  15. Imaging experiment: The Viking Mars orbiter

    USGS Publications Warehouse

    Carr, M.H.; Baum, W.A.; Briggs, G.A.; Masursky, H.; Wise, D.W.; Montgomery, D.R.

    1972-01-01

    The general objectives of the Imaging Experiment on the Viking Orbiter are to aid the selection of Viking Lander sites, to map and monitor the chosen sites during lander operations, to aid in the selection of future landing sites, and to extend our knowledge of the planet. The imaging system consists of two identical vidicon cameras each attached to a 1026 mm T/8 telescope giving approximately 1?? square field of view. From an altitude of 1500 km the picture elements will be approximately 24m apart. The vidicon is coupled with an image intensifier which provides increased sensitivity and permits electronic shuttering and image motion compensation. A vidicon readout time of 2.24 sec enables pictures to be taken in rapid sequence for contiguous coverage at high resolution. The camera differs from those previously flown to Mars by providing contiguous coverage at high resolution on a single orbital pass, by having sufficient sensitivity to use narrow band color filters at maximum resolution, and by having response in the ultraviolet. These capabilities will be utelized to supplement lander observations and to extend our knowledge particularly of volcanic, erosional, and atmospheric phenomena on Mars. ?? 1972.

  16. Irradiation of the inguinal lymph nodes in patients of differing body habitus: a comparison of techniques and resulting normal tissue complication probabilities.

    PubMed

    Brown, Paul D; Kline, Robert W; Petersen, Ivy A; Haddock, Michael G

    2004-01-01

    The treatment of the inguinal lymph nodes with radiotherapy is strongly influenced by the body habitus of the patient. The effect of 7 radiotherapy techniques on femoral head doses was studied. Three female patients of differing body habitus (ectomorph, mesomorph, endomorph) were selected. Radiation fields included the pelvis and contiguous inguinal regions and were representative of fields used in the treatment of cancers of the lower pelvis. Seven treatment techniques were compared. In the ectomorph and mesomorph, normal tissue complication probability (NTCP) for the femoral heads was lowest with use of anteroposterior (AP) and modified posteroanterior (PA) field with inguinal electron field supplements (technique 1). In the endomorph, NTCP was lowest with use of AP and modified PA field without electron field supplements (technique 2) or a 4-field approach (technique 6). Technique 1 for ectomorphs and mesomorphs and techniques 2 and 6 for endomorphs were optimal techniques for providing relatively homogeneous dose distributions within the target area while minimizing the dose to the femoral heads.

  17. Extermination and recovery of red wolf and grey wolf in the contiguous United States

    USGS Publications Warehouse

    Phillips, Michael K.; Bangs, Edward E.; Mech, L. David; Kelly, Brian T.; Fazio, Buddy B.; Macdonald, David W.; Sillero-Zubiri, Claudio

    2004-01-01

    About 150 years ago, the grey wolf (Canis lupus) was distributed throughout the contiguous United States, except for in southeastern US from central Texas to the Atlantic coast, where the red wolf (Canis rufus) occurred. Conflict with agricultural interests resulted in government-supported eradication campaigns beginning in colonial Massachusetts in 1630. Over the next 300 years, the campaigns were extended throughout the US resulting in the near extermination of both species. In recent decades, efforts to recover the red and grey wolf were carried out. This chapter summarizes extermination and recovery efforts for both species in the contiguous US.

  18. Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma

    ClinicalTrials.gov

    2017-09-12

    Stage II Contiguous Adult Diffuse Large Cell Lymphoma; Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma

  19. Building a Potential Wetland Restoration Indicator for the Contiguous United States

    EPA Science Inventory

    Wetlands provide key functions in the landscape from improving water quality, to regulating flows, to providing wildlife habitat. Over half of the wetlands in the contiguous United States (CONUS) have been converted to agricultural and urban land uses. However, over the last seve...

  20. Aeromagnetic maps of the Mazatzal Wilderness and contiguous roadless areas, Gila, Maricopa, and Yavapai counties, Arizona

    USGS Publications Warehouse

    Moss, C.K.; Abrams, G.A.

    1985-01-01

    Studies of the geology, geochemistry (Marsh and others, 1983a, b, Erickson, 1984), mines and prospects (Ellis, 1982), and mineral resource potential (Wrucke and others, 1983) of the Mazatzal Wilderness and contiguous roadless areas have been published elsewhere.

  1. The Campus Community and the Futureless Generation

    ERIC Educational Resources Information Center

    Shoben, Edward J.

    1969-01-01

    Discusses social problems and concerns which cause student alienation and activism. Stresses that task of education is to reformulate the problems and seek solutions through increased respect for personal differences and pattern of social arrangements that allows widest expression of varied constructive potentials of man. (Author/NS)

  2. 14 CFR 1260.22 - Technical publications and reports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... widest practicable dissemination of research results at any time during the course of the investigation... scientific, technical, or professional journals, the exposition of results from NASA supported research... Institution. An example follows: “Photograph courtesy of NASA and the .” (b) Reports shall be in the English...

  3. 14 CFR 1260.22 - Technical publications and reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... widest practicable dissemination of research results at any time during the course of the investigation... scientific, technical, or professional journals, the exposition of results from NASA supported research... Institution. An example follows: “Photograph courtesy of NASA and the .” (b) Reports shall be in the English...

  4. 14 CFR 1260.22 - Technical publications and reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... widest practicable dissemination of research results at any time during the course of the investigation... scientific, technical, or professional journals, the exposition of results from NASA supported research... Institution. An example follows: “Photograph courtesy of NASA and the .” (b) Reports shall be in the English...

  5. 14 CFR 1260.22 - Technical publications and reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... widest practicable dissemination of research results at any time during the course of the investigation... scientific, technical, or professional journals, the exposition of results from NASA supported research... Institution. An example follows: “Photograph courtesy of NASA and the .” (b) Reports shall be in the English...

  6. Human fascioliasis in South Africa.

    PubMed

    Black, J; Ntusi, N; Stead, P; Mayosi, B; Mendelson, M

    2013-07-29

    Human fascioliasis has the widest latitudinal, longitudinal and altitudinal distribution of any vector-borne disease, yet only 3 cases have been reported from South Africa, the last in 1964. We report 2 cases from the same geographic area associated with local consumption of watercress, suggesting an endemic focus. 

  7. SU-F-I-37: How Fat Distribution and Table Height Affect Estimates of Patient Size in CT Scanning: A Phantom Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Silosky, M; Marsh, R

    Purpose: Localizer projection radiographs acquired prior to CT scans are used to estimate patient size, affecting the function of Automatic Tube Current Modulation (ATCM) and hence CTDIvol and SSDE. Due to geometric effects, the projected patient size varies with scanner table height and with the orientation of the localizer (AP versus PA). This study sought to determine if patient size estimates made from localizer scans is affected by variations in fat distribution, specifically when the widest part of the patient is not at the geometric center of the patient. Methods: Lipid gel bolus material was wrapped around an anthropomorphic phantommore » to simulate two different body mass distributions. The first represented a patient with fairly rigid fat and had a generally oval shape. The second was bell-shaped, representing corpulent patients more susceptible to gravity’s lustful tug. Each phantom configuration was imaged using an AP localizer and then a PA localizer. This was repeated at various scanner table heights. The width of the phantom was measured from the localizer and diagnostic images using in-house software. Results: 1) The projected phantom width varied up to 39% as table height changed.2) At some table heights, the width of the phantom, designed to represent larger patients, exceeded the localizer field of view, resulting in an underestimation of the phantom width.3) The oval-shaped phantom approached a normalized phantom width of 1 at a table height several centimeters lower (AP localizer) or higher (PA localizer) than did the bell-shaped phantom. Conclusion: Accurate estimation of patient size from localizer scans is dependent on patient positioning with respect to scanner isocenter and is limited in large patients. Further, patient size is more accurately measured on projection images if the widest part of the patient, rather than the geometric center of the patient, is positioned at scanner isocenter.« less

  8. Classification of upper Mississippi River pools based on contiguous aquatic/geomorphic habitats

    USGS Publications Warehouse

    Koel, Todd M.

    2001-01-01

    Navigation pools of the upper Mississippi River (UMR) vary greatly in terms of available contiguous aquatic/geomorphic habitats. These habitats are critical for the biotic diversity and overall productivity of the floodplain corridor of each pool. In this study, similarities among pools 4-26 and an open river reach (river kilometer 47-129) of the UMR were determined from multivariate analysis of eleven habitat types that were hydrologically-contiguous (non-leveed). Isolated floodplain habitats were not included in final analyses because this isolation limits their contribution to overall riverine productivity, in part due to a lack of hydrological connectivity to the main channel during the flood pulse. Cluster analysis based on simple Euclidean distance was used to produce two major pool groups and five pool subgroups. Important habitat variables in defining pool groups, as interpreted from principal components analysis (PCA) axis 1, were contiguous floodplain shallow aquatic area and contiguous impounded area. The habitat variable most important in defining pool subgroups, as interpreted from PCA axis 2, was tertiary channel. Most notably, pool 6 was more similar to pools 14-24 than other upper pools, and pools 19 and 25 were more similar to pools 4-13 than other lower pools. These results were quite different from those of two previous investigators, primarily because only areas of non-isolated aquatic habitat were considered.

  9. 40 CFR 63.4081 - Am I subject to this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... source or group of stationary sources located within a contiguous area and under common control that... sources located within a contiguous area and under common control that is not a major source. (b) The..., spray guns or dip tanks; (4) Application of porcelain enamel, powder coating, and asphalt interior...

  10. 40 CFR 63.4081 - Am I subject to this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... source or group of stationary sources located within a contiguous area and under common control that... sources located within a contiguous area and under common control that is not a major source. (b) The..., spray guns or dip tanks; (4) Application of porcelain enamel, powder coating, and asphalt interior...

  11. 40 CFR 63.4081 - Am I subject to this subpart?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... source or group of stationary sources located within a contiguous area and under common control that... sources located within a contiguous area and under common control that is not a major source. (b) The..., spray guns or dip tanks; (4) Application of porcelain enamel, powder coating, and asphalt interior...

  12. Dynamic evaluation of two decades of WRF-CMAQ ozone simulations over the contiguous United States

    EPA Science Inventory

    Dynamic evaluation of the fully coupled Weather Research and Forecasting (WRF)– Community Multi-scale Air Quality (CMAQ) model ozone simulations over the contiguous United States (CONUS) using two decades of simulations covering the period from 1990 to 2010 is conducted to ...

  13. Wolverine gene flow across a narrow climatic niche

    Treesearch

    Michael K. Schwartz; Jeffrey P. Copeland; Neil J. Anderson; John R. Squires; Robert M. Inman; Kevin S. Mckelvey; Kristy L. Pilgrim; Lisette P. Waits; Samuel A. Cushman

    2009-01-01

    Wolverines (Gulo gulo) are one of the rarest carnivores in the contiguous United States. Effective population sizes in Montana, Idaho, and Wyoming, where most of the wolverines in the contiguous United States exist, were calculated to be 35 (credible limits, 28-52) suggesting low abundance. Landscape features that influence wolverine population...

  14. Dynamic evaluation of two decades of WRF-CMAQ ozone simulations over the contiguous United States

    EPA Science Inventory

    Dynamic evaluation of the fully coupled Weather Research and Forecasting (WRF)– Community Multi-scale Air Quality (CMAQ) model ozone simulations over the contiguous United States (CONUS) using two decades of simulations covering the period from 1990 to 2010 is conducted to assess...

  15. 48 CFR 242.1402 - Volume movements within the contiguous United States.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... administration office submits a volume movement report when— (1) Significant changes are made to the movement... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Volume movements within... SERVICES Traffic and Transportation Management 242.1402 Volume movements within the contiguous United...

  16. Hybrid numerical method for solution of the radiative transfer equation in one, two, or three dimensions.

    PubMed

    Reinersman, Phillip N; Carder, Kendall L

    2004-05-01

    A hybrid method is presented by which Monte Carlo (MC) techniques are combined with an iterative relaxation algorithm to solve the radiative transfer equation in arbitrary one-, two-, or three-dimensional optical environments. The optical environments are first divided into contiguous subregions, or elements. MC techniques are employed to determine the optical response function of each type of element. The elements are combined, and relaxation techniques are used to determine simultaneously the radiance field on the boundary and throughout the interior of the modeled environment. One-dimensional results compare well with a standard radiative transfer model. The light field beneath and adjacent to a long barge is modeled in two dimensions and displayed. Ramifications for underwater video imaging are discussed. The hybrid model is currently capable of providing estimates of the underwater light field needed to expedite inspection of ship hulls and port facilities.

  17. Analysis and design of ion-implanted bubble memory devices

    NASA Astrophysics Data System (ADS)

    Wullert, J. R., II; Kryder, M. H.

    1987-04-01

    4-μm period ion-implanted contiguous disk bubble memory circuits, designed and fabricated at AT&T Bell Laboratories, Murray Hill, NJ, have been investigated. Quasistatic testing has provided information about both the operational bias field ranges and the exact failure modes. A variety of major loop layouts were investigated and two turns found to severely limit bias field margins are discussed. The generation process, using a hairpin nucleator, was tested and several interesting failure modes were uncovered. Propagation on four different minor loop paths was observed and each was found to have characteristic failure modes. The transfer processes, both into and out of the minor loops, were investigated at higher frequencies to avoid local heating due to long transfer pulses at low frequencies. Again specific failure modes were identified. Overall bias margins for the chip were 9% at 50 Oe drive field and were limited by transfer-in.

  18. The Free Mind: Intellectual Freedom's Perils and Prospects

    ERIC Educational Resources Information Center

    Oboler, Eli

    1976-01-01

    It is more important to make available all possible shades of opinion and varieties of creative effort than to have the widest possible range of gadgets and gizmos connected by the fanciest and longest possible networks, but including only a restricted, censored, limited range of topics and their interpretations. (Author)

  19. 45 CFR 1211.1-4 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Policy. 1211.1-4 Section 1211.1-4 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-4 Policy. It is ACTION's policy to provide volunteers the widest latitude to...

  20. Technology Resources: Mathematics Accessibility for All Not Accommodation for Some

    ERIC Educational Resources Information Center

    Duranczyk, Irene M.

    2009-01-01

    When faculty and learning assistance staff create teaching documents and web pages envisioning the widest range of users they can save time while achieving access for all. There are tools and techniques available to make mathematics visual, orally, and dynamically more accessible through multimodal presentation forms. Resources from Design…

  1. 14 CFR § 1260.22 - Technical publications and reports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... widest practicable dissemination of research results at any time during the course of the investigation... scientific, technical, or professional journals, the exposition of results from NASA supported research... Institution. An example follows: “Photograph courtesy of NASA and the .” (b) Reports shall be in the English...

  2. New Technology and the Merging Media--A Time for Imagination.

    ERIC Educational Resources Information Center

    Ferris, Charles D.

    The merging of print, broadcast, mobile, and common carrier communications services offers a challenge to federal regulatory agencies. A cause for concern that the information distributed must be as untarnished and unencumbered as possible and must afford the ultimate consumer the widest assortment and the greatest discretion over its…

  3. "Spoilsport" in Drama in Education vs. Dialogic Pedagogy

    ERIC Educational Resources Information Center

    Marjanovic-Shane, Ana

    2016-01-01

    In this paper I compare and contrast two educational paradigms that both attempt to overcome alienation often experienced by students in the conventional education. These two educational paradigms are embodied in different educational practices: First, Drama in Education in its widest definition, is based on the Vygotskian views that human…

  4. 18 CFR 725.2 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Policy. 725.2 Section 725.2 Conservation of Power and Water Resources WATER RESOURCES COUNCIL IMPLEMENTATION OF EXECUTIVE..., programs, functions and resources so that the Nation may attain the widest range of beneficial uses of the...

  5. Evaluation of the International Barrier Corporation's Mark VII median barrier.

    DOT National Transportation Integrated Search

    1992-01-01

    The International Barrier Corporation's (IBC) Mark VII median barrier consists of a steel frame (10 ft long, 42 in high, and 44 in wide at its widest point) filled with sand and covered with a top plate. The barrier has the ability to absorb some of ...

  6. Spinning a Web Around Forensic Science and Senior Biology.

    ERIC Educational Resources Information Center

    Harrison, Colin R.

    1999-01-01

    Discusses a project that was established to integrate computer technology, especially the Internet, into the science classroom. Argues for the importance of providing students with a program of study that exposes them to the widest possible range of ways of gathering information for problem solving. (Author/WRM)

  7. University of Toronto: Marketing from Scratch

    ERIC Educational Resources Information Center

    Mun, Almira

    2008-01-01

    Established in 1827, the University of Toronto is regarded as one of Canada's leading academic and research institutions. It has the highest number of students (both undergraduate and graduate), the most faculty members, and the widest range of courses among Canadian universities. It has often been referred to as the "Harvard of the…

  8. Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

    ClinicalTrials.gov

    2015-04-28

    Adult Grade III Lymphomatoid Granulomatosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Epstein-Barr Virus Infection; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Post-transplant Lymphoproliferative Disorder; Progressive Hairy Cell Leukemia, Initial Treatment; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Hairy Cell Leukemia; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; T-cell Large Granular Lymphocyte Leukemia; Testicular Lymphoma; Untreated Hairy Cell Leukemia; Waldenström Macroglobulinemia

  9. Rituximab in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

    ClinicalTrials.gov

    2017-09-29

    Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Blastic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Waldenström Macroglobulinemia

  10. Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

    ClinicalTrials.gov

    2015-10-13

    Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; B-cell Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Intraocular Lymphoma; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Post-transplant Lymphoproliferative Disorder; Primary Central Nervous System Hodgkin Lymphoma; Primary Central Nervous System Non-Hodgkin Lymphoma; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Ringed Sideroblasts; Refractory Chronic Lymphocytic Leukemia; Refractory Cytopenia With Multilineage Dysplasia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Central Nervous System Hodgkin Lymphoma; Secondary Central Nervous System Non-Hodgkin Lymphoma; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Testicular Lymphoma; Waldenström Macroglobulinemia

  11. Restoration of visual orienting into a cortically blind hemifield by reversible deactivation of posterior parietal cortex or the superior colliculus.

    PubMed

    Lomber, Stephen G; Payne, Bertram R; Hilgetag, Claus C; Rushmore, JarrettR

    2002-02-01

    A contralateral hemineglect of the visual field can be induced by unilateral cooling deactivation of posterior middle suprasylvian (pMS) sulcal cortex of the posterior parietal region, and this neglect can be reversed by additional cooling deactivation of pMS cortex in the opposite hemisphere. The purpose of the present study was to test whether an enduring hemianopia induced by removal of all contiguous visual cortical areas of one hemisphere could be reversed by local cooling of pMS cortex in the opposite hemisphere. Two cats sustained large unilateral ablations of the contiguous visual areas, and cooling loops were placed in the pMS sulcus, and in contact with adjacent area 7 or posterior ectosylvian (PE) cortex of the opposite hemisphere. In both instances cooling of pMS cortex, but neither area 7 nor PE, restored a virtually normal level of orienting performance to stimuli presented anywhere in the previously hemianopic field. The reversal was highly sensitive to the extent of cooling deactivation. In a third cat, cooling deactivation of the superficial layers of the contralateral superior colliculus also restored orienting performance to a cortical ablation-induced hemianopia. This reversal was graded from center-to-periphery in a temperature-dependent manner. Neither the cortical ablation nor any of the cooling deactivations had any impact on an auditory detection and orienting task. The deactivations were localized and confirmed by reduced uptake of radiolabeled 2-deoxyglucose to be limited to the immediate vicinity of each cooling loop. The results are discussed in terms of excitation and disinhibition of visual circuits.

  12. 48 CFR 47.207-11 - Volume movements within the contiguous United States.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Volume movements within... Transportation-Related Services 47.207-11 Volume movements within the contiguous United States. (a) For purposes of contract administration, a volume movement is— (1) In DoD, the aggregate of freight shipments...

  13. History and distribution of lynx in the contiguous United States [Chapter 8

    Treesearch

    Kevin S. McKelvey

    2000-01-01

    Using written accounts, trapping records, and spatially referenced occurrence data, the authors reconstructed the history and distribution of lynx in the contiguous United States from the 1800s to the present. Records show lynx occurrence in 24 states. Data over broad scales of space and time show lynx distribution...

  14. Variability of wildland fire emissions across the contiguous United States

    Treesearch

    YongQiang Liu

    2004-01-01

    This study analyzes spatial and temporal variability of emissions from wildland fires across the contiguous US. The emissions are estimates based on a recently constructed dataset of historical fire records collected by multiple US governlnental agencies. Both wildfire and prescribed fires have the highest emissions over the Pacific coastal states. Prescribed fire...

  15. Creating contiguous forest habitat: An experimental examination on incentives and communication

    Treesearch

    Travis Warziniack; Jason F. Shogren; Gregory Parkhurst

    2007-01-01

    Forest fragmentation exists when private landowners break up large forest stands into smaller parts. Fragmentation increases risks to endangered species that find shelter in contiguous forest habitat that falls across several landowners. Policy makers interested in reuniting these forests across fences should consider how to design a voluntary incentive scheme...

  16. Dynamic Evaluation of Two Decades of WRF-CMAQ Ozone Simulations over the Contiguous United States (2017 CMAS)

    EPA Science Inventory

    Weather Research and Forecasting (WRF)–Community Multi-scale Air Quality (CMAQ) model over the contiguous United States is conducted to assess how well the changes in observed ozone air quality are simulated by the model. The changes induced by variations in meteorology and...

  17. Dynamic Evaluation of Two Decades of WRF-CMAQ Ozone Simulations over the Contiguous United States (2017 MAC-MAQ Conference Presentation)

    EPA Science Inventory

    Dynamic evaluation of two decades of ozone simulations performed with the fully coupled Weather Research and Forecasting (WRF)–Community Multi-scale Air Quality (CMAQ) model over the contiguous United States is conducted to assess how well the changes in observed ozone air ...

  18. Tornado climatology of the contiguous United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ramsdell, J.V.; Andrews, G.L.

    1986-05-01

    The characteristics of tornadoes that were reported in the contiguous United States for the period from January 1, 1954, through December 31, 1983, have been computed from data in the National Severe Storms Forecast Center tornado data base. The characteristics summarized in this report include frequency and locations of tornadoes, and their lengths, widths, and areas. Tornado strike and intensity probabilities have been estimated on a regional basis, and these estimates have been used to compute wind speeds with 10/sup -5/, 10/sup -6/, and 10/sup -7/ yr/sup -1/ probabilities of occurrence. The 10/sup -7/ yr/sup -1/ wind speeds range frommore » below 200 mph in the western United States to about 330 mph in the vicinity of Kansas and Nebraska. The appendices contain extensive tabulations of tornado statistics. Variations of the characteristics within the contiguous United States are presented in the summaries. Separate tabulations are provided for the contiguous United States, for each state, for each 5/sup 0/ and 1/sup 0/ latitude and longitude box, and for the eastern and western United States.« less

  19. A novel contiguous deletion involving NDP, MAOB and EFHC2 gene in a patient with familial Norrie disease: bilateral blindness and leucocoria without other deficits.

    PubMed

    Jia, Bei; Huang, Liping; Chen, Yaoyu; Liu, Siping; Chen, Cuihua; Xiong, Ke; Song, Lanlin; Zhou, Yulai; Yang, Xinping; Zhong, Mei

    2017-12-01

    Contiguous microdeletions of the Norrie disease pseudoglioma (NDP) region on chromosome Xp11.3 have been widely confirmed as contributing to the typical clinical features of Norrie disease (ND). However, the precise relation between genotype and phenotype could vary. The contiguous deletion of NDP and its neighbouring genes, MAOA/B and EFHC2, reportedly leads to syndromic clinical features such as microcephaly, intellectual disability, and epilepsy. Herewe report a novel contiguous microdeletion of the NDP region containing the MAOB and EFHC2 genes,which causes eye defects but no cognitive disability.We detected a deletion of 494.6 kb atXp11.3 in both the proband and carrier mother. This deletionwas then used as the molecular marker in prenatal diagnosis for two subsequent pregnancies. The deletion was absent in one of the foetuses, who remain without any abnormalities at 2 years of age. The proband shows the typical ocular clinical features of ND including bilateral retinal detachment, microphthalmia, atrophic irides, corneal opacification, and cataracts, but no symptoms of microcephaly, intellectual disability, and epilepsy. This familial study demonstrates that a deficiency in one of two MAO genes may not lead to psychomotor delay, and deletion of EFHC2 may not cause epilepsy. Our observations provide new information on the genotype-phenotype relations of MAOA/B and EFHC2 genes involved in the contiguous deletions of ND.

  20. Seamless contiguity method for parallel segmentation of remote sensing image

    NASA Astrophysics Data System (ADS)

    Wang, Geng; Wang, Guanghui; Yu, Mei; Cui, Chengling

    2015-12-01

    Seamless contiguity is the key technology for parallel segmentation of remote sensing data with large quantities. It can be effectively integrate fragments of the parallel processing into reasonable results for subsequent processes. There are numerous methods reported in the literature for seamless contiguity, such as establishing buffer, area boundary merging and data sewing. et. We proposed a new method which was also based on building buffers. The seamless contiguity processes we adopt are based on the principle: ensuring the accuracy of the boundary, ensuring the correctness of topology. Firstly, block number is computed based on data processing ability, unlike establishing buffer on both sides of block line, buffer is established just on the right side and underside of the line. Each block of data is segmented respectively and then gets the segmentation objects and their label value. Secondly, choose one block(called master block) and do stitching on the adjacent blocks(called slave block), process the rest of the block in sequence. Through the above processing, topological relationship and boundaries of master block are guaranteed. Thirdly, if the master block polygons boundaries intersect with buffer boundary and the slave blocks polygons boundaries intersect with block line, we adopt certain rules to merge and trade-offs them. Fourthly, check the topology and boundary in the buffer area. Finally, a set of experiments were conducted and prove the feasibility of this method. This novel seamless contiguity algorithm provides an applicable and practical solution for efficient segmentation of massive remote sensing image.

  1. Data integrity systems for organ contours in radiation therapy planning.

    PubMed

    Shah, Veeraj P; Lakshminarayanan, Pranav; Moore, Joseph; Tran, Phuoc T; Quon, Harry; Deville, Curtiland; McNutt, Todd R

    2018-06-12

    The purpose of this research is to develop effective data integrity models for contoured anatomy in a radiotherapy workflow for both real-time and retrospective analysis. Within this study, two classes of contour integrity models were developed: data driven models and contiguousness models. The data driven models aim to highlight contours which deviate from a gross set of contours from similar disease sites and encompass the following regions of interest (ROI): bladder, femoral heads, spinal cord, and rectum. The contiguousness models, which individually analyze the geometry of contours to detect possible errors, are applied across many different ROI's and are divided into two metrics: Extent and Region Growing over volume. After analysis, we found that 70% of detected bladder contours were verified as suspicious. The spinal cord and rectum models verified that 73% and 80% of contours were suspicious respectively. The contiguousness models were the most accurate models and the Region Growing model was the most accurate submodel. 100% of the detected noncontiguous contours were verified as suspicious, but in the cases of spinal cord, femoral heads, bladder, and rectum, the Region Growing model detected additional two to five suspicious contours that the Extent model failed to detect. When conducting a blind review to detect false negatives, it was found that all the data driven models failed to detect all suspicious contours. The Region Growing contiguousness model produced zero false negatives in all regions of interest other than prostate. With regards to runtime, the contiguousness via extent model took an average of 0.2 s per contour. On the other hand, the region growing method had a longer runtime which was dependent on the number of voxels in the contour. Both contiguousness models have potential for real-time use in clinical radiotherapy while the data driven models are better suited for retrospective use. © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

  2. Near-field investigations of the Landers earthquake sequence, April to July 1992

    USGS Publications Warehouse

    Sieh, K.; Jones, L.; Hauksson, E.; Hudnut, K.; Eberhart-Phillips, D.; Heaton, T.; Hough, S.; Hutton, K.; Kanamori, H.; Lilje, A.; Lindvall, Scott; McGill, S.F.; Mori, J.; Rubin, C.; Spotila, J.A.; Stock, J.; Thio, H.K.; Treiman, J.; Wernicke, B.; Zachariasen, J.

    1993-01-01

    The Landers earthquake, which had a moment magnitude (Mw) of 7.3, was the largest earthquake to strike the contiguous United States in 40 years. This earthquake resulted from the rupture of five major and many minor right-lateral faults near the southern end of the eastern California shear zone, just north of the San Andreas fault. Its Mw 6.1 preshock and Mw 6.2 aftershock had their own aftershocks and foreshocks. Surficial geological observations are consistent with local and far-field seismologic observations of the earthquake. Large surficial offsets (as great as 6 meters) and a relatively short rupture length (85 kilometers) are consistent with seismological calculations of a high stress drop (200 bars), which is in turn consistent with an apparently long recurrence interval for these faults.

  3. Circular free-electron laser

    DOEpatents

    Brau, Charles A.; Kurnit, Norman A.; Cooper, Richard K.

    1984-01-01

    A high efficiency, free electron laser utilizing a circular relativistic electron beam accelerator and a circular whispering mode optical waveguide for guiding optical energy in a circular path in the circular relativistic electron beam accelerator such that the circular relativistic electron beam and the optical energy are spatially contiguous in a resonant condition for free electron laser operation. Both a betatron and synchrotron are disclosed for use in the present invention. A free electron laser wiggler is disposed around the circular relativistic electron beam accelerator for generating a periodic magnetic field to transform energy from the circular relativistic electron beam to optical energy.

  4. Wideband Microstrip Antenna-Feeding Array

    NASA Technical Reports Server (NTRS)

    Huang, John

    1990-01-01

    Special impedance-matching probes help reduce feed complexity. Lightweight array of microstrip antenna elements designed to transmit and illuminate reflector antenna with circularly polarized radiation at 1,545 to 1,550 MHz and to receive circularly polarized radiation at 1,646 to 1,660 MHz. Microstrip array is cluster of 7 subarrays containing total of 28 microstrip patches. Produces cicularly polarized beam with suitable edge taper to illuminate reflector antenna. Teardrop-shaped feed probe provides gradual change of field from coaxial transmission line into microstrip substrate. Intended to be part of larger overlapping-cluster array generating multiple contiguous beams.

  5. Planning in Higher Education: A Model from Chaos Theory.

    ERIC Educational Resources Information Center

    Cutright, Marc

    This paper proposes a metaphoric perspective based on chaos theory for strategic planning by institutions of higher education. It offers 10 propositions for planning: (1) the ideal outcome of planning is planning, not a plan; (2) planning begins with a distillation of the institution's key values and purposes; (3) the widest possible universe of…

  6. Cross-Platform User Interface of E-Learning Applications

    ERIC Educational Resources Information Center

    Stoces, Michal; Masner, Jan; Jarolímek, Jan; Šimek, Pavel; Vanek, Jirí; Ulman, Miloš

    2015-01-01

    The paper discusses the development of Web educational services for specific groups. A key feature is to allow the display and use of educational materials and training services to the widest possible set of different devices, especially in the browser classic desktop computers, notebooks, tablets, mobile phones and also on different readers for…

  7. Institutional arrangements. [utilization of information derived from satellites

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The practical application of space systems is considered in terms of institutional arrangements. The evolution of space systems is examined along with examples of institutional arrangements for space systems uses or applications. An institutional framework developed to assure the widest practicable application of space system is proposed and described. Recommendations are included.

  8. Comprehensive Monitoring Program: Final Biota Annual Report for 1989. Volume 2

    DTIC Science & Technology

    1990-06-01

    samples from RMA lakes were highest in largemouth bass, a top predator . Largemouth bass and bluegill exhibited the widest geographic distribution...certification. BCtL = Siss examined with endrin concentrations below lower certified reporting limit of 0.0740 pg/g (MRI) or 0 036 pf (ESE) for aimal tipte and

  9. A Quantum Measurement Paradigm for Educational Predicates: Implications for Validity in Educational Measurement

    ERIC Educational Resources Information Center

    Cantley, Ian

    2017-01-01

    The outcomes of educational assessments undoubtedly have real implications for students, teachers, schools and education in the widest sense. Assessment results are, for example, used to award qualifications that determine future educational or vocational pathways of students. The results obtained by students in assessments are also used to gauge…

  10. Controversial Texts and Public Education.

    ERIC Educational Resources Information Center

    Smith, David L.

    Because public schools are designed to serve the widest range of interests and are committed to the ideal of democracy, teachers cannot afford to avoid teaching works or presenting ideas that offend some members of communities. Students need to learn the value of controversy and of the challenges posed by a text. Richard Wright's "Native Son" and…

  11. Diversifying Curriculum as the Practice of Repressive Tolerance

    ERIC Educational Resources Information Center

    Brookfield, Stephen

    2007-01-01

    Diversifying curriculum is often assumed to be an unequivocal good in higher education--a way of opening up an educational conversation to include the widest possible diversity of perspectives and intellectual traditions. This democratic attempt to be open and inclusive springs from a humanistic concern to have all student voices heard, all…

  12. A University-Community Partnership to Advance Research in Practice Settings: The HUB Research Model

    ERIC Educational Resources Information Center

    Dulmus, Catherine N.; Cristalli, Maria E.

    2012-01-01

    Human service organizations are uniquely positioned, given their scope of practice and access to consumers with the widest range of needs to significantly increase the national capacity for research if they were effectively equipped with the knowledge, skills, and funding to integrate research and development into their ongoing organizational…

  13. Highly efficient special sound absorbing solutions

    NASA Technical Reports Server (NTRS)

    Ionescu, M.; Petre-Lazar, S.

    1974-01-01

    Highly efficient special sound absorbing structures with the following criteria are considered: (1) A distribution surface of the sound absorbing material greater than that of the building element on which the structure is placed; (2) The highest possible absorption coefficient in the widest possible frequency band; and (3) adaptability to different construction and aesthetic conditions.

  14. A Literature Map of Dropout Prevention Interventions for Students with Disabilities

    ERIC Educational Resources Information Center

    Wilkins, Julia; Huckabee, Sloan

    2014-01-01

    This paper presents a review of the literature on dropout prevention interventions for students with disabilities. A variety of search methods, including electronic library searches, hand searches of journals, and Internet searches were used to acquire the widest possible set of research studies. To be included in this review, the studies must…

  15. 77 FR 69926 - Advisory Notice: Notice of Intent To Provide Compliance Date Extension for Air-Passenger...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... Materials Safety Administration (PHMSA), DOT. ACTION: Advisory notice. SUMMARY: PHMSA and the Federal... compliance date in a future rulemaking action. This notice is intended to provide the widest dissemination of our planned future action to all potentially affected parties and to allow for development of a...

  16. A Cross-Cultural Analysis of Imagined Interactions

    ERIC Educational Resources Information Center

    McCann, Robert M.; Honeycutt, James M.

    2006-01-01

    This study examines imagined interactions (IIs) among young adults in the United States, Thailand, and Japan. A comparison of means across cultures on II characteristics reveals that the Japanese participants have the widest variety of II partners, whereas the American participants are the most self-dominant in their IIs and demonstrate the most…

  17. Rural Adolescent Perceptions of Alcohol and Other Drug Resistance.

    ERIC Educational Resources Information Center

    Jenkins, Jeanne E.

    2001-01-01

    Used questionnaires and focus groups to examine 361 rural high schoolers' perceptions of drug resistance difficulties when offered beer, marijuana, and hard drugs. Found that drug nonusers had the widest range of explanations for resistance difficulty. Peer pressure was cited most frequently by nonusers, and seldom by heavy users. Frequent users…

  18. POTENTIAL CLIMATE WARMING EFFECTS ON ICE COVERS OF SMALL LAKES IN THE CONTIGUOUS U.S. (R824801)

    EPA Science Inventory

    Abstract

    To simulate effects of projected climate change on ice covers of small lakes in the northern contiguous U.S., a process-based simulation model is applied. This winter ice/snow cover model is associated with a deterministic, one-dimensional year-round water tem...

  19. Semantic Cuing and the Scale Insensitivity of Recency and Contiguity

    ERIC Educational Resources Information Center

    Polyn, Sean M.; Erlikhman, Gennady; Kahana, Michael J.

    2011-01-01

    In recalling a set of previously experienced events, people exhibit striking effects of recency, contiguity, and similarity: Recent items tend to be recalled best and first, and items that were studied in neighboring positions or that are similar to one another in some other way tend to evoke one another during recall. Effects of recency and…

  20. Effects of Concreteness and Contiguity on Learning from Computer-Based Reference Maps

    ERIC Educational Resources Information Center

    Srinivasan, Sribhagyam; Lewis, Daphne D.; Crooks, Steven M.

    2006-01-01

    Today's technology has reached new heights that have not been fully implemented. One of the areas where technology has not yet reached its full potential is in education. This study examined the effects of concreteness of location names and contiguity of location names with textual information on learning from computer-based reference maps. The…

  1. 77 FR 53751 - Migratory Bird Hunting; Early Seasons and Bag and Possession Limits for Certain Migratory Game...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... Migratory Game Birds in the Contiguous United States, Alaska, Hawaii, Puerto Rico, and the Virgin Islands... Seasons and Bag and Possession Limits for Certain Migratory Game Birds in the Contiguous United States... seasons; migratory game birds in Alaska, Hawaii, Puerto Rico, and the Virgin Islands; youth waterfowl day...

  2. 78 FR 53199 - Migratory Bird Hunting; Early Seasons and Bag and Possession Limits for Certain Migratory Game...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    ... Migratory Game Birds in the Contiguous United States, Alaska, Hawaii, Puerto Rico, and the Virgin Islands... Seasons and Bag and Possession Limits for Certain Migratory Game Birds in the Contiguous United States... seasons; migratory game birds in Alaska, Hawaii, Puerto Rico, and the Virgin Islands; youth waterfowl day...

  3. 76 FR 54657 - Migratory Bird Hunting; Early Seasons and Bag and Possession Limits for Certain Migratory Game...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... Migratory Game Birds in the Contiguous United States, Alaska, Hawaii, Puerto Rico, and the Virgin Islands... Bag and Possession Limits for Certain Migratory Game Birds in the Contiguous United States, Alaska...; migratory game birds in Alaska, Hawaii, Puerto Rico, and the Virgin Islands; and some extended falconry...

  4. Climate change presents increased potential for very large fires in the contiguous United States

    Treesearch

    R. Barbero; J. T. Abatzoglou; Sim Larkin; C. A. Kolden; B. Stocks

    2015-01-01

    Very large fires (VLFs) have important implications for communities, ecosystems, air quality and fire suppression expenditures. VLFs over the contiguous US have been strongly linked with meteorological and climatological variability. Building on prior modelling of VLFs (>5000 ha), an ensemble of 17 global climate models were statistically downscaled over the US...

  5. The spatial relationship between exurban development and designated wilderness lands in the contiguous United States

    Treesearch

    Allison L. Ginn; Gary T. Green; Nathan P. Nibbelink; H. Ken Cordell

    2008-01-01

    Public lands provide recreational opportunities and preserve historic and ecological values. Increases in low-density residential development in the contiguous United States pose a threat not only along the boundaries of national parks and forests, but also around uniquely valuable Wilderness areas. Development within and around protected lands can affect land...

  6. Climate and very large wildland fires in the contiguous western USA

    Treesearch

    E. Natasha Stavros; John Abatzoglou; Narasimhan K. Larkin; Donald McKenzie; E. Ashley Steel

    2014-01-01

    Very large wildfires can cause significant economic and environmental damage, including destruction of homes, adverse air quality, firefighting costs and even loss of life. We examine how climate is associated with very large wildland fires (VLWFs >=50 000 acres, or ~20234 ha) in the western contiguous USA. We used composite records of climate and fire to...

  7. Developing Information Technology for Vocational Education in Contiguous Destitute Areas Significance, Problems, and Countermeasures: The Case of the Wuling Mountain Area

    ERIC Educational Resources Information Center

    Wang, Jie; Xu, Fenghua

    2014-01-01

    Using the Wuling Mountain area as a case study, the authors discuss the significance as well as five problems of developing information technology for vocational education in contiguous destitute areas. Recommendations are provided at the end of the article. [Translated by Michelle LeSourd.

  8. Regional projections of the likelihood of very large wildland fires under a changing climate in the contiguous Western United States

    Treesearch

    Donald McKenzie; John T. Abatzoglou; E. Natasha Stavros; Narasimhan K. Larkin

    2014-01-01

    Seasonal changes in the climatic potential for very large wildfires (VLWF >= 50,000 ac~20,234 ha) across the western contiguous United States are projected over the 21st century using generalized linear models and downscaled climate projections for two representative concentration pathways (RCPs). Significant (p

  9. The spatial relationship between exurban development and designated wilderness lands in the contiguous United States

    Treesearch

    Allison L. Ginn; Gary T. Green; Nathan P. Nibbelink; H. Ken Cordell

    2009-01-01

    Public lands provide recreational opportunities and preserve historic and ecological values. Increases in low-density residential development in the contiguous United States pose a threat not only along the boundaries of national parks and forests, but also around uniquely valuable Wilderness areas. Development within and around protected lands can affect land...

  10. Mapping severe fire potential across the contiguous United States

    Treesearch

    Brett H. Davis

    2016-01-01

    The Fire Severity Mapping System (FIRESEV) project is an effort to provide critical information and tools to fire managers that enhance their ability to assess potential ecological effects of wildland fire. A major component of FIRESEV is the development of a Severe Fire Potential Map (SFPM), a geographic dataset covering the contiguous United States (CONUS) that...

  11. The NASA Technical Report Server

    NASA Technical Reports Server (NTRS)

    Nelson, Michael L.; Gottlich, Gretchen L.; Bianco, David J.; Paulson, Sharon S.; Binkley, Robert L.; Kellogg, Yvonne D.; Beaumont, Chris J.; Schmunk, Robert B.; Kurtz, Michael J.; Accomazzi, Alberto

    1995-01-01

    The National Aeronautics and Space Act of 1958 established NASA and charged it to "provide for the widest practicable and appropriate dissemination of information concerning its activities and the results thereof." The search for innovative methods to distribute NASA's information lead a grass-roots team to create the NASA Technical Report Server (NTRS), which uses the World Wide Web and other popular Internet-based information systems as search engines. The NTRS is an inter-center effort which provides uniform access to various distributed publication servers residing on the Internet. Users have immediate desktop access to technical publications from NASA centers and institutes. The NTRS is comprised of several units, some constructed especially for inclusion in NTRS, and others that are existing NASA publication services that NTRS reuses. This paper presents the NTRS architecture, usage metrics, and the lessons learned while implementing and maintaining the service. The NTRS is largely constructed with freely available software running on existing hardware. NTRS builds upon existing hardware and software, and the resulting additional exposure for the body of literature contained ensures that NASA's institutional knowledge base will continue to receive the widest practicable and appropriate dissemination.

  12. A Detailed Examination of the GPM Core Satellite Gridded Text Product

    NASA Technical Reports Server (NTRS)

    Stocker, Erich Franz; Kelley, Owen A.; Kummerow, C.; Huffman, George; Olson, William S.; Kwiatowski, John M.

    2015-01-01

    The Global Precipitation Measurement (GPM) mission quarter-degree gridded-text product has a similar file format and a similar purpose as the Tropical Rainfall Measuring Mission (TRMM) 3G68 quarter-degree product. The GPM text-grid format is an hourly summary of surface precipitation retrievals from various GPM instruments and combinations of GPM instruments. The GMI Goddard Profiling (GPROF) retrieval provides the widest swath (800 km) and does the retrieval using the GPM Microwave Imager (GMI). The Ku radar provides the widest radar swath (250 km swath) and also provides continuity with the TRMM Ku Precipitation Radar. GPM's Ku+Ka band matched swath (125 km swath) provides a dual-frequency precipitation retrieval. The "combined" retrieval (125 km swath) provides a multi-instrument precipitation retrieval based on the GMI, the DPR Ku radar, and the DPR Ka radar. While the data are reported in hourly grids, all hours for a day are packaged into a single text file that is g-zipped to reduce file size and to speed up downloading. The data are reported on a 0.25deg x 0.25 deg grid.

  13. Rate-dependent inverse-addition beta-selective mannosylation and contiguous sequential glycosylation involving beta-mannosidic bond formation.

    PubMed

    Chang, Shih-Sheng; Shih, Che-Hao; Lai, Kwun-Cheng; Mong, Kwok-Kong Tony

    2010-05-03

    The beta-selectivity of mannosylation has been found to be dependent on the addition rate of the mannosyl trichloroacetimidate donor in an inverse-addition (I-A) procedure. This rate dependent I-A procedure can improve the selectivity of direct beta-mannosylation and is applicable to orthogonal glycosylations of thioglycoside acceptors. Further elaboration of this novel procedure enables the development of the contiguous sequential glycosylation strategy, which streamlines the preparation of oligosaccharides invoking beta-mannosidic bond formation. The synthetic utility of the contiguous glycosylation strategy was demonstrated by the preparation of the trisaccharide core of human N-linked glycoproteins and the trisaccharide repeating unit of the O-specific polysaccharide found in the cellular capsule of Salmonelle bacteria.

  14. Overlap Properties of Clouds Generated by a Cloud Resolving Model

    NASA Technical Reports Server (NTRS)

    Oreopoulos, L.; Khairoutdinov, M.

    2002-01-01

    In order for General Circulation Models (GCMs), one of our most important tools to predict future climate, to correctly describe the propagation of solar and thermal radiation through the cloudy atmosphere a realistic description of the vertical distribution of cloud amount is needed. Actually, one needs not only the cloud amounts at different levels of the atmosphere, but also how these cloud amounts are related, in other words, how they overlap. Currently GCMs make some idealized assumptions about cloud overlap, for example that contiguous cloud layers overlap maximally and non-contiguous cloud layers overlap in a random fashion. Since there are difficulties in obtaining the vertical profile of cloud amount from observations, the realism of the overlap assumptions made in GCMs has not been yet rigorously investigated. Recently however, cloud observations from a relatively new type of ground radar have been used to examine the vertical distribution of cloudiness. These observations suggest that the GCM overlap assumptions are dubious. Our study uses cloud fields from sophisticated models dedicated to simulate cloud formation, maintenance, and dissipation called Cloud Resolving Models . These models are generally considered capable of producing realistic three-dimensional representation of cloudiness. Using numerous cloud fields produced by such a CRM we show that the degree of overlap between cloud layers is a function of their separation distance, and is in general described by a combination of the maximum and random overlap assumption, with random overlap dominating as separation distances increase. We show that it is possible to parameterize this behavior in a way that can eventually be incorporated in GCMs. Our results seem to have a significant resemblance to the results from the radar observations despite the completely different nature of the datasets. This consistency is encouraging and will promote development of new radiative transfer codes that will estimate the radiation effects of multi-layer cloud fields more accurately.

  15. Resolving Magnetic Flux Patches at the Surface of the Core

    NASA Technical Reports Server (NTRS)

    OBrien, Michael S.

    1996-01-01

    The geomagnetic field at a given epoch can be used to partition the surface of the liquid outer core into a finite number of contiguous regions in which the radial component of the magnetic flux density, B (sub r), is of one sign. These flux patches are instrumental in providing detail to surface fluid flows inferred from the changing geomagnetic field and in evaluating the validity of the frozen-flux approximation on which such inferences rely. Most of the flux patches in models of the modem field are small and enclose little flux compared to the total unsigned flux emanating from the core. To demonstrate that such patches are not required to explain the most spatially complete and accurate data presently available, those from the Magsat mission, I have constructed a smooth core field model that fits the Magsat data but does not possess small flux patches. I conclude that our present knowledge of the geomagnetic field does not allow us to resolve these features reliably at the core-mantle boundary; thus we possess less information about core flow than previously believed.

  16. Effect of prenatal exposure to mobile phone on pyramidal cell numbers in the mouse hippocampus: a stereological study.

    PubMed

    Rağbetli, Murat Cetin; Aydinlioğlu, Atif; Koyun, Necat; Rağbetli, Cennet; Karayel, Metin

    2009-01-01

    Because of the possible risk factor for the health, World Health Organization (WHO) recommended the study with animals on the developing nervous system concerning the exposure to radiofrequency (RF) field. A few studies related to hippocampal exposure are available, which indicate the impact of RF field in some parameters. The present study investigated the effect of exposure to mobile phone on developing hippocampus. Male and female Swiss albino mice were housed as control and mobile phone exposed groups. The pregnant animals in tested group were exposed to the effects of mobile phone in a room possessing the exposure system. The left hemispheres of the brains were processed by frozen microtome. The sections obtained were stained with Hematoxylin & Eosin. For cell counting by the optical fractionator method, a pilot study was first performed. Hippocampal areas were analyzed using Axiovision software running on a personal computer. The optical dissector, systematically and randomly spaced, was focused to the widest profile of the pyramidal cell nucleus. No significant difference in pyramidal cell number of total Cornu Ammonis (CA) sectors of hippocampus was found between the control and the mobile phone exposed groups (p > .05). It was concluded that further study is needed in this field due to popular use of mobile telephones and relatively high exposure to the developing brain.

  17. Downscaling with a nested regional climate model in near-surface fields over the contiguous United States

    NASA Astrophysics Data System (ADS)

    Wang, Jiali; Kotamarthi, Veerabhadra R.

    2014-07-01

    The Weather Research and Forecasting (WRF) model is used for dynamic downscaling of 2.5-degree National Centers for Environmental Prediction-U.S. Department of Energy Reanalysis II (NCEP-R2) data for 1980-2010 at 12 km resolution over most of North America. The model's performance for surface air temperature and precipitation is evaluated by comparison with high-resolution observational data sets. The model's ability to add value is investigated by comparison with NCEP-R2 data and a 50 km regional climate simulation. The causes for major model bias are studied through additional sensitivity experiments with various model setup/integration approaches and physics representations. The WRF captures the main features of the spatial patterns and annual cycles of air temperature and precipitation over most of the contiguous United States. However, simulated air temperatures over the south central region and precipitation over the Great Plains and the Southwest have significant biases. Allowing longer spin-up time, reducing the nudging strength, or replacing the WRF Single-Moment six-class microphysics with Morrison microphysics reduces the bias over some subregions. However, replacing the Grell-Devenyi cumulus parameterization with Kain-Fritsch shows no improvement. The 12 km simulation does add value above the NCEP-R2 data and the 50 km simulation over mountainous and coastal zones.

  18. When Spatial and Temporal Contiguities Help the Integration in Working Memory: "A Multimedia Learning" Approach

    ERIC Educational Resources Information Center

    Mammarella, Nicola; Fairfield, Beth; Di Domenico, Alberto

    2013-01-01

    Two experiments examined the effects of spatial and temporal contiguities in a working memory binding task that required participants to remember coloured objects. In Experiment 1, a black and white drawing and a corresponding phrase that indicated its colour perceptually were either near or far (spatial study condition), while in Experiment 2,…

  19. Aspergillus terreus infection of pseudoaneurysm of aortofemoral vascular graft with contiguous vertebral osteomyelitis.

    PubMed

    Glotzbach, R E

    1982-02-01

    This is a case report of a patient who developed several unusual complications of an aortofemoral vascular graft. These were thrombosis, pseudoaneurysm, and infection. There was an Aspergillus terreus infection of the pseudoaneurysm of the vascular prosthesis. A contiguous vertebral osteomyelitis due to A. terreus subsequently developed. This represented a localized, invasive form of aspergillosis.

  20. Reserve selection with minimum contiguous area restrictions: An application to open space protection planning in suburban Chicago

    Treesearch

    Sandor F. Toth; Robert Haight; Stephanie A. Snyder; Sonney George; James R. Miller; Mark S. Gregory; Adam M. Skibbe

    2009-01-01

    Conservation efforts often require site or parcel selection strategies that lead to spatially cohesive reserves. Although habitat contiguity is thought to be conducive to the persistence of many sensitive species, availability of funding and suitable land may restrict the extent to which this spatial attribute can be pursued in land management or conservation. Using...

  1. New solar cell and clean unit system platform (CUSP) for earth and environmental science

    NASA Astrophysics Data System (ADS)

    Ishibashi, A.; Matsuoka, T.; Enomoto, R.; Yasutake, M.

    2017-11-01

    We have investigated InGaN-based multi-striped orthogonal photon-photocarrier propagation solar cell (MOP3SC) in which sunlight propagates in a direction being orthogonal to that of photocarriers generated by the sunlight. Thanks to the orthogonality, in MOP3SC, absorption of the sunlight and collection of the photocarriers can be simultaneously and independently optimized with no trade-off. Furthermore, by exploiting the degree of freedom along the photon propagation and using multi-semiconductor stripes in which the incoming photons first encounter the widest gap semiconductor, and the narrowest at last, we can convert the whole solar spectrum into electricity resulting in the high conversion efficiency. For processing MOP3SC, we have developed Clean Unit System Platform (CUSP), which turns out to be able to serve as clean versatile environment having low power-consumption and high cost-performance. CUSP is suitable not only for processing devices, but also for cross-disciplinary fields, including medical/hygienic applications.

  2. NASA space and Earth science data on CD-ROM

    NASA Technical Reports Server (NTRS)

    Towheed, Syed S.

    1993-01-01

    The National Space Science Data Center (NSSDC) is very interested in facilitating the widest possible use of the scientific data acquired through NASA spaceflight missions. Therefore, NSSDC has participated with projects and data management elements throughout the NASA science environment in the creation, archiving, and dissemination of data using Compact Disk-Read Only Memory (CD-ROM). This CD-ROM technology has the potential to enable the dissemination of very large data volumes at very low prices to a great many researchers, students and their teachers, and others. This catalog identifies and describes the scientific CD-ROM's now available from NSSDC including the following data sets: Einstein Observatory CD-ROM, Galileo Cruise Imaging on CD-ROM, International Halley Watch, IRAS Sky Survey Atlas, Infrared Thermal Mapper (IRTM), Magellan (MIDR), Magellan (ARCDR's), Magellan (GxDR's), Mars Digital Image Map (MDIM), Outer Planets Fields & Particles Data, Pre-Magellan, Selected Astronomical Catalogs, TOMS Gridded Ozone Data, TOMS Ozone Image Data, TOMS Update, Viking Orbiter Images of Mars, and Voyager Image.

  3. Improved MEGAN predictions of biogenic isoprene in the contiguous United States

    NASA Astrophysics Data System (ADS)

    Wang, Peng; Schade, Gunnar; Estes, Mark; Ying, Qi

    2017-01-01

    Isoprene emitted from biogenic sources significantly contributes to ozone and secondary organic aerosol formation in the troposphere. The Model of Emissions of Gases and Aerosols from Nature (MEGAN) has been widely used to estimate isoprene emissions from local to global scales. However, previous studies have shown that MEGAN significantly over-predicts isoprene emissions in the contiguous United States (US). In this study, ambient isoprene concentrations in the US were simulated by the Community Multiscale Air Quality (CMAQ) model (v5.0.1) using biogenic emissions estimated by MEGAN v2.10 with several different gridded isoprene emission factor (EF) fields. Best isoprene predictions were obtained with the EF field based on the Biogenic Emissions Landcover Database v4 (BELD4) from US EPA for its Biogenic Emission Inventory System (BEIS) model v3.61 (MEGAN-BEIS361). A seven-month simulation (April to October 2011) of isoprene emissions with MEGAN-BEIS361 and ambient concentrations using CMAQ shows that observed spatial and temporal variations (both diurnal and seasonal) of isoprene concentrations can be well predicted at most non-urban monitors using isoprene emission estimation from the MEGAN-BEIS361 without significant biases. The predicted monthly average vertical column density of formaldehyde (HCHO), a reactive volatile organic compound with significant contributions from isoprene oxidation, generally agree with the spatial distribution of HCHO column density derived using satellite data collected by the Ozone Monitoring Instrument (OMI), although summer month vertical column densities in the southeast US were overestimated, which suggests that isoprene emission might still be overestimated in that region. The agreement between observation and prediction may be further improved if more accurate PAR values, such as those derived from satellite-based observations, were used in modeling the biogenic emissions.

  4. Application of a New Resampling Method to SEM: A Comparison of S-SMART with the Bootstrap

    ERIC Educational Resources Information Center

    Bai, Haiyan; Sivo, Stephen A.; Pan, Wei; Fan, Xitao

    2016-01-01

    Among the commonly used resampling methods of dealing with small-sample problems, the bootstrap enjoys the widest applications because it often outperforms its counterparts. However, the bootstrap still has limitations when its operations are contemplated. Therefore, the purpose of this study is to examine an alternative, new resampling method…

  5. From the Pulpits to the Boards: A Study on Prospective Second Career Teachers in Turkey

    ERIC Educational Resources Information Center

    Unisen, Ali; Polat, Huseyin

    2016-01-01

    Teaching career is the widest state employment type in Turkey. The career is resourced by many higher education institutions besides the ones deploying regular teacher training programs. Teacher candidates other than the graduates from education faculties have to attend a program specially designed to instruct on foundations of education such as…

  6. Use of Screen Capture to Produce Media for Organic Chemistry

    ERIC Educational Resources Information Center

    D'Angelo, John G.

    2014-01-01

    Although many students learn best in different ways, the widest range of students can be reached when multiple modes of input are employed, especially if the student is simultaneously completing a set of handwritten notes. Computers, meanwhile, have led to countless changes in society, and education has not been exempt from these changes. Students…

  7. Career Funneling: How Elite Students Learn to Define and Desire ''Prestigious'' Jobs

    ERIC Educational Resources Information Center

    Binder, Amy J.; Davis, Daniel B.; Bloom, Nick

    2016-01-01

    Elite universities are credited as launch points for the widest variety of meaningful careers. Yet, year after year at the most selective universities, nearly half the graduating seniors head to a surprisingly narrow band of professional options. Over the past few decades, this has largely been into the finance and consulting sectors, but…

  8. Improved-Bandwidth Transimpedance Amplifier

    NASA Technical Reports Server (NTRS)

    Chapsky, Jacob

    2009-01-01

    The widest available operational amplifier, with the best voltage and current noise characteristics, is considered for transimpedance amplifier (TIA) applications where wide bandwidth is required to handle fast rising input signals (as for time-of-flight measurement cases). The added amplifier inside the TIA feedback loop can be configured to have slightly lower voltage gain than the bandwidth reduction factor.

  9. Proposals for a Dynamic Library. Technical Report.

    ERIC Educational Resources Information Center

    Salton, Gerard

    The current library environment is first examined, and an attempt is made to explain why the standard approaches to the library problem have been less productive than had been anticipated. A new design is then introduced for modern library operations based on a two-fold strategy: on the input side, the widest possible utilization should be made of…

  10. Autographa caljfornica nuclear polyhedrosis virus replication in non-permissive Lymantria dispar cell lines

    Treesearch

    Edward M. Dougherty; David Guzo; Kathleen S. Shields; Dwight E. Lynn; Susan K. Braun

    1991-01-01

    Autographa californica nuclear polyhedrosis virus (AcNPV) the prototypic group A baculovirus, has the widest reported host range of the baculoviruses and is considered to be one of the most virulent baculoviruses studied. The gypsy moth Lymantria dispar is not considered a natural host of AcNPV, however. To determine the factors...

  11. 33 CFR 165.1407 - Security Zones; Oahu, HI.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... between Harbor Entrance Channel Light 6 and the jetty point day beacon at 21°19.5′ N/158°07.26′ W. (7) Kahe Point, Oahu. All waters adjacent to the Hawaiian Electric Company power plant at Kahe Point within... affect the widest publicity, including the use of broadcast notice to mariners and publication in the...

  12. 33 CFR 165.1407 - Security Zones; Oahu, HI.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... between Harbor Entrance Channel Light 6 and the jetty point day beacon at 21°19.5′ N/158°07.26′ W. (7) Kahe Point, Oahu. All waters adjacent to the Hawaiian Electric Company power plant at Kahe Point within... affect the widest publicity, including the use of broadcast notice to mariners and publication in the...

  13. 33 CFR 165.1407 - Security Zones; Oahu, HI.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... between Harbor Entrance Channel Light 6 and the jetty point day beacon at 21°19.5′ N/158°07.26′ W. (7) Kahe Point, Oahu. All waters adjacent to the Hawaiian Electric Company power plant at Kahe Point within... affect the widest publicity, including the use of broadcast notice to mariners and publication in the...

  14. Exploring Reading: Empowering Readers with Special Needs.

    ERIC Educational Resources Information Center

    Builder, Philip

    Focusing on the affective aspects of children's learning, this book presents a view of learners with special needs in the widest sense, including their responses to their environments at school and at home; and the dynamics of the literacy-learning processes--how to view them and what to look for. The book also introduces BRAT (Building Reading…

  15. A Cool Sport Full of Physics

    ERIC Educational Resources Information Center

    Hache, Alain

    2008-01-01

    Of all sports, ice hockey is possibly the one with the widest array of physics elements in it. The game provides many examples that can bring physics to life in the classroom. Ice hockey (or just "hockey" as many Canadians would say) sees athletes sliding on ice at high speeds and in various ways, shooting and slapping pucks, and…

  16. A Comprehensive Approach to Managing School Safety: Case Studies in Catalonia, Spain

    ERIC Educational Resources Information Center

    Díaz-Vicario, Anna; Gairín Sallán, Joaquín

    2017-01-01

    Background: Schools should be safe spaces for students, teaching staff and non-teaching staff. For the concept of "safety" to be meaningful, it must be interpreted broadly to encompass well-being in its widest sense. A common challenge for schools and educational authorities is, therefore, to manage school safety appropriately not only…

  17. Reforming Remediation: College Students Mainstreamed into Statistics Are More Likely to Succeed

    ERIC Educational Resources Information Center

    Logue, Alexandra W.; Douglas, Daniel; Watanabe-Rose, Mari

    2017-01-01

    Across the United States, more than half of entering freshmen discover they are ineligible for college-level coursework each year, most commonly in math. The readiness gap is widest when considering students at nonselective two-year colleges, and students who are black, Hispanic, or from low-income families. It often spells disaster for students…

  18. Eleven Colors That Are Almost Never Confused

    NASA Astrophysics Data System (ADS)

    Boynton, Robert M.

    1989-08-01

    1.1. Three functions of color vision. Setting aside the complex psychological effects of color, related to esthetics, fashion, and mood, three relatively basic functions of color vision, which can be examined scientifically, are discernable. (1) With the eye in a given state of adaptation, color vision allows the perception of signals that otherwise would be below threshold, and therefore lost to perception. Evidence for this comes from a variety of two-color threshold experiments. (2) Visible contours can be maintained by color differences alone, regardless of the relative radiances of the two parts of the field whose junction defines the border. For achromatic vision, contour disappears at the isoluminant point. (3) Color specifies what seems to be an absolute property of a surface, one that enhances its recognizability and allows a clearer separation and classification of non-contiguous elements in the visual field.

  19. VizieR Online Data Catalog: PHAT. XIX. Formation history of M31 disk (Williams+, 2017)

    NASA Astrophysics Data System (ADS)

    Williams, B. F.; Dolphin, A. E.; Dalcanton, J. J.; Weisz, D. R.; Bell, E. F.; Lewis, A. R.; Rosenfield, P.; Choi, Y.; Skillman, E.; Monachesi, A.

    2018-05-01

    The data for this study come from the Panchromatic Hubble Andromeda Treasury (PHAT) survey (Dalcanton+ 2012ApJS..200...18D ; Williams+ 2014, J/ApJS/215/9). Briefly, PHAT is a multiwavelength HST survey mapping 414 contiguous HST fields of the northern M31 disk and bulge in six broad wavelength bands from the near-ultraviolet to the near-infrared. The survey obtained data in the F275W and F336W bands with the UVIS detectors of the Wide-Field Camera 3 (WFC3) camera, the F475W and F814W bands in the WFC detectors of the Advanced Camera for Surveys (ACS) camera, and the F110W and F160W bands in the IR detectors of the WFC3 camera. (4 data files).

  20. Explaining the Modality Effect in Multimedia Learning: Is It Due to a Lack of Temporal Contiguity with Written Text and Pictures?

    ERIC Educational Resources Information Center

    Schuler, Anne; Scheiter, Katharina; Rummer, Ralf; Gerjets, Peter

    2012-01-01

    The study examined whether the modality effect is caused by either high visuo-spatial load or a lack of temporal contiguity when processing written text and pictures. Students (N = 147) viewed pictures on the development of tornados, which were accompanied by either spoken or written explanations presented simultaneously with, before, or after the…

  1. Hebbian Learning is about contingency, not contiguity, and explains the emergence of predictive mirror neurons.

    PubMed

    Keysers, Christian; Perrett, David I; Gazzola, Valeria

    2014-04-01

    Hebbian Learning should not be reduced to contiguity, as it detects contingency and causality. Hebbian Learning accounts of mirror neurons make predictions that differ from associative learning: Through Hebbian Learning, mirror neurons become dynamic networks that calculate predictions and prediction errors and relate to ideomotor theories. The social force of imitation is important for mirror neuron emergence and suggests canalization.

  2. Double separate versus contiguous pituitary adenomas: MRI features and endocrinological follow up.

    PubMed

    Roberts, Sammie; Borges, Manuel Thomas; Lillehei, Kevin O; Kleinschmidt-DeMasters, B K

    2016-10-01

    Double pituitary adenomas are defined as two adenomas within a gland. These have distinct light microscopic and immunohistochemical features and may be clearly-separate or contiguous. Most reports have focused on the various hormonal combinations in double tumors rather than on any potential increased risk for residual mass or endocrinopathy. Departmental files were searched to identify all double adenomas from 1/1/2000 to 3/1/2016, with review of magnetic resonance imaging (MRI) to determine if the dual nature of the lesions could be discerned retrospectively after histologic diagnosis of double adenoma. All cases were immunostained for standard anterior pituitary hormones. Eight cases were identified: 2 follicle-stimulating hormone (FSH)/alpha subunit (ASU) + prolactinoma (PRL); 1 PRL + corticotroph (ACTH); 1 hormone-negative + PRL; 1 ACTH + ASU/growth hormone (GH)/PRL; 1 GH/PR + PRL; 1 FSH/ASU, + ACTH; 1 GH + luteinizing hormone (LH). One patient had clearly-separate lesions identified preoperatively and required two surgical procedures for gross total resection. A second patient had 2 lesions recognized at surgery and afterwards on retrospective neuroimaging. The remaining 6 patients had double adenomas discovered at the time of histologic examination that were not resolvable at surgery or on retrospective neuroimaging. Four patients, 2 with clearly-separate and 2 with contiguous double adenomas, had persistent MRI abnormalities, and one had continued endocrine abnormalities. Double contiguous pituitary adenomas are difficult to anticipate preoperatively or to resolve intraoperatively. Although double contiguous adenomas are much more common than double separate lesions, both have a risk for subtotal resection and, thus, residual mass and/or endocrinopathy may ensue.

  3. Defining hip fracture with claims data: outpatient and provider claims matter.

    PubMed

    Berry, S D; Zullo, A R; McConeghy, K; Lee, Y; Daiello, L; Kiel, D P

    2017-07-01

    Medicare claims are commonly used to identify hip fractures, but there is no universally accepted definition. We found that a definition using inpatient claims identified fewer fractures than a definition including outpatient and provider claims. Few additional fractures were identified by including inconsistent diagnostic and procedural codes at contiguous sites. Medicare claims data is commonly used in research studies to identify hip fractures, but there is no universally accepted definition of fracture. Our purpose was to describe potential misclassification when hip fractures are defined using Medicare Part A (inpatient) claims without considering Part B (outpatient and provider) claims and when inconsistent diagnostic and procedural codes occur at contiguous fracture sites (e.g., femoral shaft or pelvic). Participants included all long-stay nursing home residents enrolled in Medicare Parts A and B fee-for-service between 1/1/2008 and 12/31/2009 with follow-up through 12/31/2011. We compared the number of hip fractures identified using only Part A claims to (1) Part A plus Part B claims and (2) Part A and Part B claims plus discordant codes at contiguous fracture sites. Among 1,257,279 long-stay residents, 40,932 (3.2%) met the definition of hip fracture using Part A claims, and 41,687 residents (3.3%) met the definition using Part B claims. 4566 hip fractures identified using Part B claims would not have been captured using Part A claims. An additional 227 hip fractures were identified after considering contiguous fracture sites. When ascertaining hip fractures, a definition using outpatient and provider claims identified 11% more fractures than a definition with only inpatient claims. Future studies should publish their definition of fracture and specify if diagnostic codes from contiguous fracture sites were used.

  4. Multiple focal and macroreentrant left atrial tachycardias originating from a spontaneous scar at the contiguous aorta-left atrium area in a patient with hypertrophic cardiomyopathy: a case report.

    PubMed

    Yazaki, Kyoichiro; Ajiro, Yoichi; Mori, Fumiaki; Watanabe, Masahiro; Tsukamoto, Kei; Saito, Takashi; Mizobuchi, Keiko; Iwade, Kazunori

    2017-01-17

    Spontaneous scar-related left atrial tachycardia (AT) is a rare arrhythmia. We describe a patient with hypertrophic cardiomyopathy (HCM) who developed multiple, both focal and macroreentrant left ATs associated with a spontaneous scar located at the aorta-left atrium (LA) contiguous area. A 65-year-old man with HCM complained of palpitations. Twelve-lead electrocardiogram showed narrow QRS tachycardia with 2:1 atrioventricular conduction. Two sessions of radiofrequency ablation (RFA) were required to eliminate all left ATs. In the first session, 3-dimensional electroanatomical mapping fused with the image constructed by multi-detector computed tomography showed a clockwise macroreentrant AT (AT1) associated with a low-voltage or dense scar area located along the aorta-LA contiguous area. AT1 was eliminated by RFA to the narrow isthmus with slow conduction velocity within the scar. Additional ATs (AT2-AT4) occurred 1 month after the first ablation. In the second session, AT2 and AT3 were identified as focal ATs with centrifugal propagation and few accompanying fragmentations, and AT4 as a macroreentrant AT with features similar to AT1. AT2 and AT3 were successfully eliminated by performing RFA to the earliest activation site, and AT4 was terminated by performing RFA to the narrow isthmus with slow conduction velocity. No ATs have recurred for 11 months after these RFAs. Interestingly, the substrate for all left ATs was associated with the aorta-LA contiguous area. To our knowledge, this is the first case of multiple, both focal and macroreentrant left ATs associated with a contiguous aorta-LA spontaneous scar area in a patient with HCM.

  5. Dependence of prevalence of contiguous pathways in proteins on structural complexity.

    PubMed

    Thayer, Kelly M; Galganov, Jesse C; Stein, Avram J

    2017-01-01

    Allostery is a regulatory mechanism in proteins where an effector molecule binds distal from an active site to modulate its activity. Allosteric signaling may occur via a continuous path of residues linking the active and allosteric sites, which has been suggested by large conformational changes evident in crystal structures. An alternate possibility is that the signal occurs in the realm of ensemble dynamics via an energy landscape change. While the latter was first proposed on theoretical grounds, increasing evidence suggests that such a control mechanism is plausible. A major difficulty for testing the two methods is the ability to definitively determine that a residue is directly involved in allosteric signal transduction. Statistical Coupling Analysis (SCA) is a method that has been successful at predicting pathways, and experimental tests involving mutagenesis or domain substitution provide the best available evidence of signaling pathways. However, ascertaining energetic pathways which need not be contiguous is far more difficult. To date, simple estimates of the statistical significance of a pathway in a protein remain to be established. The focus of this work is to estimate such benchmarks for the statistical significance of contiguous pathways for the null model of selecting residues at random. We found that when 20% of residues in proteins are randomly selected, contiguous pathways at the 6 Å cutoff level were found with success rates of 51% in PDZ, 30% in p53, and 3% in MutS. The results suggest that the significance of pathways may have system specific factors involved. Furthermore, the possible existence of false positives for contiguous pathways implies that signaling could be occurring via alternate routes including those consistent with the energetic landscape model.

  6. Zoom‐in comparative genomic hybridisation arrays for the characterisation of variable breakpoint contiguous gene syndromes

    PubMed Central

    Johnston, Jennifer J; Walker, Robert L; Davis, Sean; Facio, Flavia; Turner, Joyce T; Bick, David P; Daentl, Donna L; Ellison, Jay W; Meltzer, Paul S; Biesecker, Leslie G

    2007-01-01

    Contiguous gene syndromes cause disorders via haploinsufficiency for adjacent genes. Some contiguous gene syndromes (CGS) have stereotypical breakpoints, but others have variable breakpoints. In CGS that have variable breakpoints, the extent of the deletions may be correlated with severity. The Greig cephalopolysyndactyly contiguous gene syndrome (GCPS‐CGS) is a multiple malformation syndrome caused by haploinsufficiency of GLI3 and adjacent genes. In addition, non‐CGS GCPS can be caused by deletions or duplications in GLI3. Although fluorescence in situ hybridisation (FISH) can identify large deletion mutations in patients with GCPS or GCPS‐CGS, it is not practical for identification of small intragenic deletions or insertions, and it is difficult to accurately characterise the extent of the large deletions using this technique. We have designed a custom comparative genomic hybridisation (CGH) array that allows identification of deletions and duplications at kilobase resolution in the vicinity of GLI3. The array averages one probe every 730 bp for a total of about 14 000 probes over 10 Mb. We have analysed 16 individuals with known or suspected deletions or duplications. In 15 of 16 individuals (14 deletions and 1 duplication), the array confirmed the prior results. In the remaining patient, the normal CGH array result was correct, and the prior assessment was a false positive quantitative polymerase chain reaction result. We conclude that high‐density CGH array analysis is more sensitive than FISH analysis for detecting deletions and provides clinically useful results on the extent of the deletion. We suggest that high‐density CGH array analysis should replace FISH analysis for assessment of deletions and duplications in patients with contiguous gene syndromes caused by variable deletions. PMID:17098889

  7. The Receiver System for the Ooty Wide Field Array

    NASA Astrophysics Data System (ADS)

    Subrahmanya, C. R.; Prasad, P.; Girish, B. S.; Somashekar, R.; Manoharan, P. K.; Mittal, A. K.

    2017-03-01

    The legacy Ooty Radio Telescope (ORT) is being reconfigured as a 264-element synthesis telescope, called the Ooty Wide Field Array (OWFA). Its antenna elements are the contiguous 1.92 m sections of the parabolic cylinder. It will operate in a 38-MHz frequency band centred at 326.5 MHz and will be equipped with a digital receiver including a 264-element spectral correlator with a spectral resolution of 48 kHz. OWFA is designed to retain the benefits of equatorial mount, continuous 9-hour tracking ability and large collecting area of the legacy telescope and use of modern digital techniques to enhance the instantaneous field-of-view by more than an order of magnitude. OWFA has unique advantages for contemporary investigations related to large scale structure, transient events and space weather watch. In this paper, we describe the RF subsystems, digitizers and fibre optic communication of OWFA and highlight some specific aspects of the system relevant for the observations planned during the initial operation.

  8. Rituximab and Dexamethasone in Treating Patients With Low-Grade Non-Hodgkin Lymphoma

    ClinicalTrials.gov

    2017-04-14

    Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Marginal Zone Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Marginal Zone Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Marginal Zone Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Marginal Zone Lymphoma; Waldenstrom Macroglobulinemia

  9. 78 FR 59429 - Endangered and Threatened Wildlife and Plants; Revised Designation of Critical Habitat for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...We, the U.S. Fish and Wildlife Service, propose to designate revised critical habitat for the contiguous U.S. distinct population segment (DPS) of the Canada lynx under the Endangered Species Act of 1973, as amended, and to revise the boundary of the Canada lynx DPS. These proposed revisions fulfill our obligations under two settlement agreements. The revised critical habitat proposed rule also addresses issues raised by two courts in 2010. If we finalize this rule as proposed, it would extend the Endangered Species Act's protections to the Canada lynx wherever it occurs in the contiguous United States, including New Mexico, and it would revise this species' critical habitat. The effect of this regulation is to conserve the Canada lynx and its habitats in the contiguous United States under the Endangered Species Act.

  10. A honeycomb-like three-dimensional metamaterial absorber via super-wideband and wide-angle performances at millimeter wave and low THz frequencies

    NASA Astrophysics Data System (ADS)

    Vahidi, Alireza; Rajabalipanah, Hamid; Abdolali, Ali; Cheldavi, Ahmad

    2018-04-01

    Achieving wideband absorption via three-dimensional (3D) metamaterials has revealed as a new emerging innovative field of research, especially in recent years. Here, a novel 3D metamaterial absorber (MA) having a sixfold symmetry is designed which consists of periodic resistive honeycomb-like units. The proposed 3D MA exhibits a strong absorptivity above 90% in the widest bandwidth ever reported to the authors' knowledge from 50 to 460 GHz (the bandwidth ratio larger than 1:9), covering both millimeter wave and low -terahertz spectra. To understand the physical mechanism of absorption, the electric field and surface current distributions, the power loss density as well as the deteriorating effects of the high-order Floquet modes are monitored and discussed. As a distinctive feature in comparison to the similar 3D MAs, our engineered absorber provides multiple resonances, contributing to further broadening of the operating bandwidth. In addition, it is shown that the honeycomb-like MA retains its polarization-insensitive absorption in a wide range of incident wave angles and polarization angles. Due to flexibility of the design, these superior performances can be simply extended to terahertz, infrared and visible frequencies, potentially leading to many promising applications in imaging, sensing, and camouflage technology.

  11. The challenge of cultural gerontology.

    PubMed

    Twigg, Julia; Martin, Wendy

    2015-06-01

    Over the last decade, Cultural Gerontology has emerged as one of the most vibrant elements of writing about age (Twigg, J., & Martin, W. (Eds.) (2015). The Routledge handbook of cultural gerontology. London: Routledge). Reflecting the wider Cultural Turn, it has expanded the field of gerontology beyond all recognition. No longer confined to frailty, or the dominance of medical and social welfare perspectives, cultural gerontology addresses the nature and experience of later years in the widest sense. In this review, we will explore how the Cultural Turn, which occurred across the social sciences and humanities in the late 20th century, came to influence age studies. We will analyze the impulses that led to the emergence of the field and the forces that have inhibited or delayed its development. We will explore how cultural gerontology has recast aging studies, widening its theoretical and substantive scope, taking it into new territory intellectually and politically, presenting this in terms of 4 broad themes that characterize the work: subjectivity and identity; the body and embodiment; representation and the visual; and time and space. Finally, we will briefly address whether there are problems in the approach. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Immediate Truth--Temporal Contiguity between a Cognitive Problem and Its Solution Determines Experienced Veracity of the Solution

    ERIC Educational Resources Information Center

    Topolinski, Sascha; Reber, Rolf

    2010-01-01

    A temporal contiguity hypothesis for the experience of veracity is tested which states that a solution candidate to a cognitive problem is more likely to be experienced as correct the faster it succeeds the problem. Experiment 1 varied the onset time of the appearance of proposed solutions to anagrams (50 ms vs. 150 ms) and found for both correct…

  13. Hebbian Learning is about contingency not contiguity and explains the emergence of predictive mirror neurons

    PubMed Central

    Keysers, Christian; Perrett, David I.; Gazzola, Valeria

    2015-01-01

    Hebbian Learning should not be reduced to contiguity since it detects contingency and causality. Hebbian Learning accounts of mirror neurons make predictions that differ from associative learning: through Hebbian Learning mirror neurons become dynamic networks that calculate predictions and prediction errors and relate to ideomotor theories. The social force of imitation is important for mirror neuron emergence and suggests canalization. PMID:24775162

  14. Electronic Devices with Strontium Barrier Film and Process for Making Same

    DTIC Science & Technology

    1998-08-20

    structure of the barrier film on an atomic level where the barrier film is comprised of a plurality of contiguous monolayers, while FIG. 7B shows another...another embodiment where the barrier film is comprised of a plurality of contiguous monolayers in which different monolayers thereof are formed of...High Energy Electron 10 Diffraction (RHEED) diagnostic system directed toward the substrate 26. A diffusion barrier precursor compound effusion

  15. Electronic Devices with Composite Atomic Barrier Film and Process for Making Same

    DTIC Science & Technology

    1998-08-20

    structure of the barrier film on an atomic level where the barrier film is comprised of a plurality of contiguous monolayers, while FIG. 7B shows...another embodiment where the barrier film is comprised of a plurality of contiguous monolayers in which different monolayers thereof are formed of...High Energy Electron 10 Diffraction (RHEED) diagnostic system directed toward the substrate 26. A diffusion barrier precursor compound effusion

  16. The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units.

    PubMed

    Lancrey, Astrid; Safa, Layal; Chatain, Jean; Delagoutte, Emmanuelle; Riou, Jean-François; Alberti, Patrizia; Saintomé, Carole

    2018-03-01

    Replication protein A (RPA) is a single-stranded DNA binding protein involved in replication and in telomere maintenance. During telomere replication, G-quadruplexes (G4) can accumulate on the lagging strand template and need to be resolved. It has been shown that human RPA is able to unfold a single G4. Nevertheless, the G-strand of human telomeres is prone to fold into higher-order structures formed by contiguous G-quadruplexes. To understand how RPA deals with these structures, we studied its interaction with telomeric G-strands folding into an increasing number of contiguous G4s. The aim of this study was to determine whether the efficiency of binding/unfolding of hRPA to telomeric G-strands depends on the number of G4 units. Our data show that the number n of contiguous G4 units (n ≥ 2) does not affect the efficiency of hRPA to coat transiently exposed single-stranded telomeric G-strands. This feature may be essential in preventing instability due to G4 structures during telomere replication. Copyright © 2017 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). All rights reserved.

  17. Single-mode very wide tunability in laterally coupled semiconductor lasers with electrically controlled reflectivities

    NASA Astrophysics Data System (ADS)

    Griffel, Giora; Chen, Howard Z.; Grave, Ilan; Yariv, Amnon

    1991-04-01

    The operation of a novel multisection structure comprised of laterally coupled gain-guided semiconductor lasers is demonstrated. It is shown that tunable single longitudinal mode operation can be achieved with a high degree of frequency selectivity. The device has a tuning range of 14.5 nm, the widest observed to date in a monolithic device.

  18. Transfer of a Pyemotes egg parastie phoretic on western pine bark beetles to the southern pine beetle

    Treesearch

    John C. Moser

    1981-01-01

    Pyemotes giganticus has the widest phoretic latitude of any known Pyemotes probably riding all scolytids and at least one tenebrionid beetle associate. The female heteromorph is not phoretic. The feeding latitude is narrow; the mite is known to feed only on scolytid eggs, and then reluctantly. Parasitism of a natural host,

  19. Development of a Software-Defined Radar

    DTIC Science & Technology

    2017-10-01

    waveform to the widest available (unoccupied) instantaneous bandwidth in real time. Consequently, the radar range resolution and target detection are...LabVIEW The matched filter range profile is calculated in real time using fast Fourier transform (FFT) operations to perform a cross-correlation...between the transmitted waveform and the received complex data. Figure 4 demonstrates the block logic used to achieve real -time range profile

  20. The "How To's" of Using Word Processors and Database Managers with Qualitative Data: A Primer for Professionals.

    ERIC Educational Resources Information Center

    Stuck, M. F.

    This guide provides an introduction to the use of microcomputers with qualitative data. It is deliberately non-specific and rudimentary in order to be of maximum benefit to the widest possible audience of beginning microcomputer users who wish to analyze their data using software that is not specifically designed for qualitative data analysis. The…

  1. 50 CFR 648.51 - Gear and crew restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... possession on board such vessels shall not exceed 31 ft (9.4 m) measured at the widest point in the bail of..., i.e., the metal ring bag and the mouth frame, or bail, of the dredge are not attached, and such that... through issuance of a letter of authorization. (4) A certified at-sea observer is on board, as required by...

  2. Industry and Higher Education: Collaboration To Improve Students' Learning and Training.

    ERIC Educational Resources Information Center

    Wright, Peter W. G., Ed.

    This volume of essays sets out to consider the contributions that higher education and industry, understood in the widest sense, could make to improving the quality of students' learning and to increasing its relevance to the needs of employment. The essays fall into four parts, the first of which is on how the relationship between industry and…

  3. Holding the Center: How One Jewish Day School Negotiates Differences in a Pluralistic Community

    ERIC Educational Resources Information Center

    Selis, Allen Harold

    2010-01-01

    This study centers on the experiences of students and religious study faculty in the high school division of "CDS," a successful Kindergarten through Twelfth grade Jewish day school that defines itself as a "community" institution. The school affirms a high-profile commitment to including "the widest spectrum of Jewish practice and belief" in its…

  4. Women's Perspectives on Retention in Higher Education in Jordan: Commute and Choice

    ERIC Educational Resources Information Center

    Allaf, Carine

    2013-01-01

    Jordan is viewed as a country of social, political, and economic and advancement. It currently leads the region in literacy rates and is well on its way to achieving gender equity. However, some reports claim that Jordan maintains the widest gender gap in higher education completion in the region while others report that the percentage of females…

  5. Golden Is the Sand: Memory and Hope in Evaluation Policy and Evaluation Practice

    ERIC Educational Resources Information Center

    Datta, Lois-ellin

    2009-01-01

    Going from thought to action in influencing evaluation policy is an overdue, untried, and perhaps anxious-making role for the American Evaluation Association. We will need good courage, sustained conversation, and the widest views. The courage is needed in remembering that although this isn't going to be fast or easy, evaluation policies make a…

  6. Needs of a Science Editor

    NASA Astrophysics Data System (ADS)

    Dreissigacker, O.

    2005-12-01

    None of the classic media sources report in greater depth about this science discipline than monthly astronomy magazines. They may not reach the widest audience, but their readers are 100% interested in astronomy, astrophysics and spaceflight, so the targeting is perfect! This article provides some insight into the production and selection process using examples from ASTRONOMIE HEUTE (AH), the German edition of Sky & Telescope (S&T).

  7. Phase 1 Integrated Systems Test and Characterization Report for the 5-Megawatt Dynamometer and Controllable Grid Interface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wallen, Robert B; Lambert, Scott R; Gevorgian, Vahan

    This report details the commissioning of the 5-megawatt dynamometer at the National Wind Technology Center at the National Renewable Energy Laboratory. The purpose of these characterization tests were to verify the dynamometer's performance over the widest possible range of operating conditions, gain insight into system-level behavior, and establish confidence in measurement data.

  8. Work Environment: A Profile of the Social Climate of Nursing Faculty in an Academic Setting.

    ERIC Educational Resources Information Center

    Doughty, Jana; May, Barbara; Butell, Sue; Tong, Vivian

    2002-01-01

    The perceptions of 15 full-time and 7 part-time nursing faculty regarding their work environment at a liberal arts college were gathered using the Moos Work Environment Scale. Scores were congruent in 7 of 10 social climate subscales. Widest discrepancies were in the areas of work pressures, physical comfort, and managerial control. (Contains 42…

  9. Regenerating shortleaf pine: results of a 5-year cooperative research initiative

    Treesearch

    James P. Barnett; John C. Brissette

    2007-01-01

    Shortleaf pine (Pinus echinata Mill.) is unique among the southern pines. It has the widest natural range and thrives on shallow rocky soils of the Interior Highlands, where most other pine species perform poorly. Although wood quality is excellent, it has been one of the most neglected species from both research and operational standpoints. It has a...

  10. A 1 kA-class cryogen-free critical current characterization system for superconducting coated conductors.

    PubMed

    Strickland, N M; Hoffmann, C; Wimbush, S C

    2014-11-01

    A cryogenic electrical transport measurement system is described that is particularly designed to meet the requirements for routine and effective characterization of commercial second generation high-temperature superconducting (HTS) wires in the form of coated conductors based on YBa2Cu3O7. Specific design parameters include a base temperature of 20 K, an applied magnetic field capability of 8 T (provided by a HTS split-coil magnet), and a measurement current capacity approaching 1 kA. The system accommodates samples up to 12 mm in width (the widest conductor size presently commercially available) and 40 mm long, although this is not a limiting size. The sample is able to be rotated freely with respect to the magnetic field direction about an axis parallel to the current flow, producing field angle variations in the standard maximum Lorentz force configuration. The system is completely free of liquid cryogens for both sample cooling and magnet cool-down and operation. Software enables the system to conduct a full characterization of the temperature, magnetic field, and field angle dependence of the critical current of a sample without any user interaction. The system has successfully been used to measure a wide range of experimental and commercially-available superconducting wire samples sourced from different manufacturers across the full range of operating conditions. The system encapsulates significant advances in HTS magnet design and efficient cryogen-free cooling technologies together with the capability for routine and automated high-current electrical transport measurements at cryogenic temperatures. It will be of interest to both research scientists investigating superconductor behavior and commercial wire manufacturers seeking to accurately characterize the performance of their product under all desired operating conditions.

  11. Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

    ClinicalTrials.gov

    2017-12-22

    Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; Adult Langerhans Cell Histiocytosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Mast Cell Leukemia; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Myeloid/NK-cell Acute Leukemia; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Anemia; Refractory Multiple Myeloma; Secondary Acute Myeloid Leukemia; Secondary Myelofibrosis; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma; Testicular Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Waldenstrom Macroglobulinemia

  12. Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas

    ClinicalTrials.gov

    2018-03-02

    Adult Grade III Lymphomatoid Granulomatosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Grade III Lymphomatoid Granulomatosis; Childhood Immunoblastic Large Cell Lymphoma; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Progressive Hairy Cell Leukemia, Initial Treatment; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage 0 Chronic Lymphocytic Leukemia; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Hodgkin Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Hodgkin Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; T-cell Large Granular Lymphocyte Leukemia; Testicular Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia; Untreated Hairy Cell Leukemia; Waldenström Macroglobulinemia

  13. Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

    ClinicalTrials.gov

    2015-03-05

    Hematopoietic/Lymphoid Cancer; Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Atypical Chronic Myeloid Leukemia; Blastic Phase Chronic Myelogenous Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Chronic Myelogenous Leukemia; Childhood Myelodysplastic Syndromes; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Isolated Plasmacytoma of Bone; Juvenile Myelomonocytic Leukemia; Meningeal Chronic Myelogenous Leukemia; Myelodysplastic/Myeloproliferative Disease, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma

  14. Optical and biochemical properties of a southwest Florida whiting event

    NASA Astrophysics Data System (ADS)

    Long, Jacqueline S.; Hu, Chuanmin; Robbins, Lisa L.; Byrne, Robert H.; Paul, John H.; Wolny, Jennifer L.

    2017-09-01

    ;Whiting; in oceanography is a term used to describe a sharply defined patch of water that contains high levels of suspended, fine-grained calcium carbonate (CaCO3). Whitings have been reported in many oceanic and lake environments, and recently have been reported in southwest Florida coastal waters. Here, field and laboratory measurements were used to study optical, biological, and chemical properties of whiting waters off southwest Florida. No significant difference was found in chlorophyll a concentrations between whiting and outside waters (non-whiting water), but average particle backscattering coefficients in whiting waters were double those in outside waters, and remote sensing reflectance in whiting waters was higher at all wavelengths (400-700 nm). While other potential causes cannot be completely ruled out, particle composition and biochemical differences between sampled whiting water, contiguous water, and outside water indicate a biologically precipitated mode of whiting formation. Taxonomic examination of marine phytoplankton samples collected during a whiting event revealed a community dominated by autotrophic picoplankton and a small (<10 μm), centric diatom species, identified as Thalassiosira sp. through the use of scanning electron microscopy. Amorphous to fully formed crystals of CaCO3 were observed along the girdle bands of Thalassiosira sp. cells and autotrophic picoplankton cells. Although carbonate parameters differed from whiting and contiguous to outside water, more sampling is needed to determine if these results are statistically significant.

  15. Downscaling with a nested regional climate model in near-surface fields over the contiguous United States: WRF dynamical downscaling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Jiali; Kotamarthi, Veerabhadra R.

    The Weather Research and Forecasting (WRF) model is used for dynamic downscaling of 2.5 degree National Centers for Environmental Prediction-U.S. Department of Energy Reanalysis II (NCEP-R2) data for 1980-2010 at 12 km resolution over most of North America. The model's performance for surface air temperature and precipitation is evaluated by comparison with high-resolution observational data sets. The model's ability to add value is investigated by comparison with NCEP-R2 data and a 50 km regional climate simulation. The causes for major model bias are studied through additional sensitivity experiments with various model setup/integration approaches and physics representations. The WRF captures themore » main features of the spatial patterns and annual cycles of air temperature and precipitation over most of the contiguous United States. However, simulated air temperatures over the south central region and precipitation over the Great Plains and the Southwest have significant biases. Allowing longer spin-up time, reducing the nudging strength, or replacing the WRF Single-Moment 6-class microphysics with Morrison microphysics reduces the bias over some subregions. However, replacing the Grell-Devenyi cumulus parameterization with Kain-Fritsch shows no improvement. The 12 km simulation does add value above the NCEP-R2 data and the 50 km simulation over mountainous and coastal zones.« less

  16. EnviroAtlas - Agricultural Water Demand by 12-Digit HUC for the Conterminous United States

    EPA Pesticide Factsheets

    The national agricultural water demand metric provides insight into the amount of water currently used for agricultural irrigation in the contiguous United States. The values are based on 2005 irrigation water use; combined 2010 crop, 2006 land use, and 2001 remotely sensed irrigation location estimates; and have been summarized by watershed or 12-digit hydrologic unit code (HUC). Agricultural irrigation water use, as defined in this case, meets a variety of needs before, during, and after growing seasons (e.g., dust suppression, field preparation, chemical application, weed control, salt removal from root zones, frost protection, crop cooling, and harvesting). Estimates include self-supplied surface and groundwater, as well as supplies from irrigation-specific organizations (e.g., companies, districts, cooperatives, government). This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  17. Electrical and spectroscopic analysis of mono- and multi-tip pulsed corona discharges in air at atmospheric pressure

    NASA Astrophysics Data System (ADS)

    Mraihi, A.; Merbahi, N.; Yousfi, M.; Abahazem, A.; Eichwald, O.

    2011-12-01

    This work is devoted to the analysis of experimental results obtained in dry air at atmospheric pressure in a positive point-to-plane corona discharge under a pulsed applied voltage in the cases of anodic mono- and multi-tips. In the mono-tip case, the peak corona current is analysed as a function of several experimental parameters such as magnitude, frequency and duration of pulsed voltage and gap distance. The variation of the corona discharge current is correlated with the ozone production. Then in the multi-tip case, the electrical behaviour is analysed as a function of the distance between two contiguous tips and the tip number in order to highlight the region of creation active species for the lowest dissipated power. Intensified charge-coupled device pictures and electric field calculations as a function of inter-tip distance are performed to analyse the mutual effect between two contiguous tips. The optical emission spectra are measured in the UV-visible-NIR wavelength range between 200 nm and 800 nm, in order to identify the main excited species formed in an air corona discharge such as the usual first and second positive systems with first negative systems of molecular nitrogen. The identification of atomic species (O triplet and N) and the quenching of NOγ emission bands are also emphasized.

  18. Electronic Devices with Barium Barrier Film and Process for Making Same

    DTIC Science & Technology

    1998-08-20

    structure of the barrier film on an atomic level 15 where the barrier .film is comprised of a plurality of contiguous monolayers, while FIG. 7B...yet another embodiment where the barrier film is comprised of a plurality of 20 contiguous monolayers in which different monolayers thereof are...barrier precursor compound effusion cell, for example a barium fluoride, strontium fluoride or the like effusion cell, is provided at 32, and has a

  19. Electronic Devices with Barrier Film and Process for Making Same

    DTIC Science & Technology

    1998-08-20

    the barrier film on an atomic level where the barrier film is comprised of a plurality of contiguous monolayers, while FIG. 7B shows another...embodiment where the barrier film is comprised of a plurality of contiguous monolayers in which different monolayers thereof are formed of different...compound effusion cell, for example a barium fluoride, strontium fluoride or the like effusion cell, is provided at 32, and has a shutter 33. A

  20. Electronic Devices with Rubidium Barrier Film and Process for Making Same

    DTIC Science & Technology

    1998-08-20

    barrier film is comprised of a plurality of contiguous monolayers, while FIG. 7B shows another embodiment of the 20 invention where the barrier film is... plurality of contiguous monolayers in which different monolayers thereof are formed of different types of metal atoms. -10- FIG. 8 is a schematic...system directed toward the substrate 26. A diffusion barrier precursor compound effusion cell, for example a barium fluoride, strontium fluoride or the

  1. ABACAS: algorithm-based automatic contiguation of assembled sequences

    PubMed Central

    Assefa, Samuel; Keane, Thomas M.; Otto, Thomas D.; Newbold, Chris; Berriman, Matthew

    2009-01-01

    Summary: Due to the availability of new sequencing technologies, we are now increasingly interested in sequencing closely related strains of existing finished genomes. Recently a number of de novo and mapping-based assemblers have been developed to produce high quality draft genomes from new sequencing technology reads. New tools are necessary to take contigs from a draft assembly through to a fully contiguated genome sequence. ABACAS is intended as a tool to rapidly contiguate (align, order, orientate), visualize and design primers to close gaps on shotgun assembled contigs based on a reference sequence. The input to ABACAS is a set of contigs which will be aligned to the reference genome, ordered and orientated, visualized in the ACT comparative browser, and optimal primer sequences are automatically generated. Availability and Implementation: ABACAS is implemented in Perl and is freely available for download from http://abacas.sourceforge.net Contact: sa4@sanger.ac.uk PMID:19497936

  2. A superior edge preserving filter with a systematic analysis

    NASA Technical Reports Server (NTRS)

    Holladay, Kenneth W.; Rickman, Doug

    1991-01-01

    A new, adaptive, edge preserving filter for use in image processing is presented. It had superior performance when compared to other filters. Termed the contiguous K-average, it aggregates pixels by examining all pixels contiguous to an existing cluster and adding the pixel closest to the mean of the existing cluster. The process is iterated until K pixels were accumulated. Rather than simply compare the visual results of processing with this operator to other filters, some approaches were developed which allow quantitative evaluation of how well and filter performs. Particular attention is given to the standard deviation of noise within a feature and the stability of imagery under iterative processing. Demonstrations illustrate the performance of several filters to discriminate against noise and retain edges, the effect of filtering as a preprocessing step, and the utility of the contiguous K-average filter when used with remote sensing data.

  3. Do sign language videos improve Web navigation for Deaf Signer users?

    PubMed

    Fajardo, Inmaculada; Parra, Elena; Cañas, José J

    2010-01-01

    The efficacy of video-based sign language (SL) navigation aids to improve Web search for Deaf Signers was tested by two experiments. Experiment 1 compared 2 navigation aids based on text hyperlinks linked to embedded SL videos, which differed in the spatial contiguity between the text hyperlink and SL video (contiguous vs. distant). Deaf Signers' performance was similar in Web search using both aids, but a positive correlation between their word categorization abilities and search efficiency appeared in the distant condition. In Experiment 2, the contiguous condition was compared with a text-only hyperlink condition. Deaf Signers became less disorientated (used shorter paths to find the target) in the text plus SL condition than in the text-only condition. In addition, the positive correlation between word categorization abilities and search only appeared in the text-only condition. These findings suggest that SL videos added to text hyperlinks improve Web search efficiency for Deaf Signers.

  4. Contiguous triple spinal dysraphism associated with Chiari malformation Type II and hydrocephalus: an embryological conundrum between the unified theory of Pang and the unified theory of McLone.

    PubMed

    Dhandapani, Sivashanmugam; Srinivasan, Anirudh

    2016-01-01

    Triple spinal dysraphism is extremely rare. There are published reports of multiple discrete neural tube defects with intervening normal segments that are explained by the multisite closure theory of primary neurulation, having an association with Chiari malformation Type II consistent with the unified theory of McLone. The authors report on a 1-year-old child with contiguous myelomeningocele and lipomyelomeningocele centered on Type I split cord malformation with Chiari malformation Type II and hydrocephalus. This composite anomaly is probably due to select abnormalities of the neurenteric canal during gastrulation, with a contiguous cascading impact on both dysjunction of the neural tube and closure of the neuropore, resulting in a small posterior fossa, probably bringing the unified theory of McLone closer to the unified theory of Pang.

  5. Rhesus monkeys (Macaca mulatta), video tasks, and implications for stimulus-response spatial contiguity

    NASA Technical Reports Server (NTRS)

    Rumbaugh, Duane M.; Richardson, W. Kirk; Washburn, David A.; Hopkins, William D.; Savage-Rumbaugh, E. Sue

    1989-01-01

    Recent reports support the argument that the efficiency of primate learning is compromised to the degree that there is spatial discontiguity between discriminands and the locus of response. Experiments are reported here in which two rhesus monkeys easily mastered precise control of a joystick to respond to a variety of computer-generated targets despite the fact that the joystick was located 9 to 18 cm from the video screen. It is argued that stimulus-response contiguity is a significant parameter of learning only to the degree that the monkey visually attends to the directional movements of its hand in order to displace discriminands. If attention is focused on the effects of the hand's movement rather than on the hand itself, stimulus-response contiguity is no longer a primary parameter of learning. The implications of these results for mirror-guided studies are discussed.

  6. Hexabundles: first results

    NASA Astrophysics Data System (ADS)

    Bryant, Julia J.; O'Byrne, John W.; Bland-Hawthorn, Joss; Leon-Saval, Sergio G.

    2010-07-01

    New multi-core imaging fibre bundles - hexabundles - being developed at the University of Sydney will provide simultaneous integral field spectroscopy for hundreds of celestial sources across a wide angular field. These are a natural progression from the use of single fibres in existing galaxy surveys. Hexabundles will allow us to address fundamental questions in astronomy without the biases introduced by a fixed entrance aperture. We have begun to consider instrument concepts that exploit hundreds of hexabundles over the widest possible field of view. To this end, we have characterised the performance of a 61-core fully fused hexabundle and 5 unfused bundles with 7 cores each. All fibres in bundles have 100 micron cores. In the fused bundle, the cores are distorted from a circular shape in order to achieve a higher fill fraction. The unfused bundles have circular cores and five different cladding thicknesses which affect the fill fraction. We compare the optical performance of all 6 bundles and find that the advantage of smaller interstitial holes (higher fill fraction) is outweighed by the increase in FRD, crosstalk and the poor optical performance caused by the deformation of the fibre cores. Uniformly high throughput and low cross-talk are essential for imaging faint astronomical targets with sufficient resolution to disentangle the dynamical structure. Devices already under development will have 100-200 unfused cores, although larger formats are feasible. The light-weight packaging of hexabundles is sufficiently flexible to allow existing robotic positioners to make use of them.

  7. Lunar surface remanent magnetic fields detected by the electron reflection method

    NASA Technical Reports Server (NTRS)

    Lin, R. P.; Anderson, K. A.; Bush, R.; Mcguire, R. E.; Mccoy, J. E.

    1976-01-01

    We present maps of the lunar surface remanent magnetic fields detected by the electron reflection method. These maps provide substantial coverage of the latitude band from 30 N southward to 30 S with a resolution of about 40 km and a sensitivity of about 0.2 gamma at the lunar surface. Regions of remanent magnetization are observed ranging in size from the resolution limit of 1.25 deg to above approximately 60 deg. The largest contiguous region fills the Big Backside Basin where it is intersected by the spacecraft orbital tracks. Preliminary analyses of the maps show that the source regions of lunar limb compressions correspond to regions of strong surface magnetism, and that there does not appear to be sharply discontinuous magnetization at the edges of maria. We also analyze the electron reflection observations to obtain information on the direction and distribution of magnetization in the Van de Graaff anomaly region.

  8. Recovery of phase inconsistencies in continuously moving table extended field of view magnetic resonance imaging acquisitions.

    PubMed

    Kruger, David G; Riederer, Stephen J; Rossman, Phillip J; Mostardi, Petrice M; Madhuranthakam, Ananth J; Hu, Houchun H

    2005-09-01

    MR images formed using extended FOV continuously moving table data acquisition can have signal falloff and loss of lateral spatial resolution at localized, periodic positions along the direction of table motion. In this work we identify the origin of these artifacts and provide a means for correction. The artifacts are due to a mismatch of the phase of signals acquired from contiguous sampling fields of view and are most pronounced when the central k-space views are being sampled. Correction can be performed using the phase information from a periodically sampled central view to adjust the phase of all other views of that view cycle, making the net phase uniform across each axial plane. Results from experimental phantom and contrast-enhanced peripheral MRA studies show that the correction technique substantially eliminates the artifact for a variety of phase encode orders. Copyright (c) 2005 Wiley-Liss, Inc.

  9. Diamagnetic composite material structure for reducing undesired electromagnetic interference and eddy currents in dielectric wall accelerators and other devices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caporaso, George J.; Poole, Brian R.; Hawkins, Steven A.

    2015-06-30

    The devices, systems and techniques disclosed here can be used to reduce undesired effects by magnetic field induced eddy currents based on a diamagnetic composite material structure including diamagnetic composite sheets that are separated from one another to provide a high impedance composite material structure. In some implementations, each diamagnetic composite sheet includes patterned conductor layers are separated by a dielectric material and each patterned conductor layer includes voids and conductor areas. The voids in the patterned conductor layers of each diamagnetic composite sheet are arranged to be displaced in position from one patterned conductor layer to an adjacent patternedmore » conductor layer while conductor areas of the patterned conductor layers collectively form a contiguous conductor structure in each diamagnetic composite sheet to prevent penetration by a magnetic field.« less

  10. Energy Emergency Management Information System (EEMIS): Functional requirements

    NASA Astrophysics Data System (ADS)

    1980-10-01

    These guidelines state that in order to create the widest practicable competition, the system's requirements, with few exceptions, must be expressed in functional terms without reference to specific hardware or software products, and that wherever exceptions are made a statement of justification must be provided. In addition, these guidelines set forth a recommended maximum threshold limit of annual contract value for schedule contract procurements.

  11. Rich-Poor Income Gap Hits 40-Year High As Poverty Rate Stalls.

    ERIC Educational Resources Information Center

    Center on Budget and Policy Priorities, Washington, DC.

    On September 26, 1990, the Census Bureau released its 1989 figures on poverty and income which showed that no significant progress was made in reducing poverty in 1989, and that gaps between rich and poor and between the wealthy and the middle class hit their widest points in more than 40 years. Although 1989 marked the seventh year of economic…

  12. Undermining the Very Democracy We Seek to Create: Discussion Practices in Adult Education and the Dangers of Repressive Tolerance

    ERIC Educational Resources Information Center

    Brookfield, Stephen

    2005-01-01

    Discussion has long held an honored place in the pantheon of lionized adult education practices. One of the most frequently venerated aspects of discussion is opening up conversation to include the widest possible diversity of perspectives and intellectual traditions. This democratic attempt to be open and inclusive is held to represent what is…

  13. Evolution from Collaborative Learning to Symbiotic E-Learning: Creation of New E-Learning Environment for Knowledge Society

    ERIC Educational Resources Information Center

    Songhao, He; Saito, Kenji; Maeda, Takashi; Kubo, Takara

    2011-01-01

    For people who live in the knowledge society which has rapidly been changing, learning in the widest sense becomes indispensable in all phases of working, living and playing. The construction of an environment, to meet the demands of people who need to acquire new knowledge and skills as the need arises, and enlighten each other regularly, is…

  14. Teaching Students To Annotate and Underline Text Effectively--Guidelines and Procedures. College Reading and Learning Assistance Technical Report No. 87-02.

    ERIC Educational Resources Information Center

    Nist, Sherrie L.

    Of all the effective strategies available to college developmental reading students, annotating (noting important ideas or examples in text margins) and underlining have the widest appeal among students and the most practical application in any course. Annotating/underlining serves a dual function: students can isolate key ideas at the time of the…

  15. A comparison of the effects of El Niño and El Niño Modoki on subdaily extreme precipitation occurrences across the contiguous United States

    Treesearch

    Lejiang Yu; Shiyuan Zhong; Warren E. Heilman; Xindi Bian

    2017-01-01

    Intense precipitation over a short duration is a major cause of flash floods. Using hourly rainfall data from the North America Land Data Assimilation System Phase 2 from 1979 to 2013, we compared the differences in the response of the subdaily extreme precipitation occurrences across the contiguous U.S. to strong anomalous warming over the eastern equatorial Pacific...

  16. CHAMA RIVER CANYON WILDERNESS AND CONTIGUOUS ROADLESS AREA, NEW MEXICO.

    USGS Publications Warehouse

    Ridgley, Jennie L.; Light, Thomas D.

    1984-01-01

    Results of mineral surveys indicate that the Chama River Canyon Wilderness and contiguous roadless area in new Mexico have a probable mineral-resource potential for copper with associated uranium and silver. Gypsum occurs throughout the area, exposed in the canyon walls. Further study of the wilderness should concentrate on exploratory drilling to test the oil and gas potential of Pennsylvanian strata and evaluate vanadium anomalies in the Todilto as a prospecting guide for locating uranium.

  17. Electronic Devices with Cesium Barrier Film and Process for Making Same

    DTIC Science & Technology

    1998-08-20

    interfacial structure of the barrier film on an atomic level where the barrier film is comprised of a plurality of contiguous monolayers, while FIG. 7B shows...another 20 embodiment where the barrier film is comprised of a plurality of contiguous monolayers in which different monolayers thereof are formed...compound effusion cell, for example a barium fluoride, strontium fluoride or the like effusion cell, is provided at 32, and has a shutter 33. A

  18. The impact of climate change on the characteristics of the frost-free season over the contiguous USA as projected by the NARCCAP model ensembles

    Treesearch

    Shiyuan Zhong; Lejiang Yu; Julie A. Winkler; Ying Tang; Warren E. Heilman; Xiandi. Bian

    2017-01-01

    Understanding the impacts of climate change on frost-free seasons is key to designing effective adaptation strategies for ecosystem management and agricultural production. This study examines the potential changes in the frost-free season length between historical (1971−2000) and future (2041−2070) periods over the contiguous USA with a focus on spatial variability and...

  19. Modulation of early cortical processing during divided attention to non-contiguous locations

    PubMed Central

    Frey, Hans-Peter; Schmid, Anita M.; Murphy, Jeremy W.; Molholm, Sophie; Lalor, Edmund C.; Foxe, John J.

    2015-01-01

    We often face the challenge of simultaneously attending to multiple non-contiguous regions of space. There is ongoing debate as to how spatial attention is divided under these situations. While for several years the predominant view was that humans could divide the attentional spotlight, several recent studies argue in favor of a unitary spotlight that rhythmically samples relevant locations. Here, this issue was addressed using high-density electrophysiology in concert with the multifocal m-sequence technique to examine visual evoked responses to multiple simultaneous streams of stimulation. Concurrently, we assayed the topographic distribution of alpha-band oscillatory mechanisms, a measure of attentional suppression. Participants performed a difficult detection task that required simultaneous attention to two stimuli in contiguous (undivided) or non-contiguous parts of space. In the undivided condition, the classical pattern of attentional modulation was observed, with increased amplitude of the early visual evoked response and increased alpha amplitude ipsilateral to the attended hemifield. For the divided condition, early visual responses to attended stimuli were also enhanced and the observed multifocal topographic distribution of alpha suppression was in line with the divided attention hypothesis. These results support the existence of divided attentional spotlights, providing evidence that the corresponding modulation occurs during initial sensory processing timeframes in hierarchically early visual regions and that suppressive mechanisms of visual attention selectively target distracter locations during divided spatial attention. PMID:24606564

  20. Agency attribution: event-related potentials and outcome monitoring.

    PubMed

    Bednark, Jeffery G; Franz, Elizabeth A

    2014-04-01

    Knowledge about the effects of our actions is an underlying feature of voluntary behavior. Given the importance of identifying the outcomes of our actions, it has been proposed that the sensory outcomes of self-made actions are inherently different from those of externally caused outcomes. Thus, the outcomes of self-made actions are likely to be more motivationally significant for an agent. We used event-related potentials to investigate the relationship between the perceived motivational significance of an outcome and the attribution of agency in the presence of others. In our experiment, we assessed agency attribution in the presence of another agent by varying the degree of contiguity between participants' self-made actions and the sensory outcome. Specifically, we assessed the feedback correct-related positivity (fCRP) and the novelty P3 measures of an outcome's motivational significance and unexpectedness, respectively. Results revealed that both the fCRP and participants' agency attributions were significantly influenced by action-outcome contiguity. However, when action-outcome contiguity was ambiguous, novelty P3 amplitude was a reliable indicator of agency attribution. Prior agency attributions were also found to influence attribution in trials with ambiguous and low action-outcome contiguity. Participants' use of multiple cues to determine agency is consistent with the cue integration theory of agency. In addition to these novel findings, this study supports growing evidence suggesting that reinforcement processes play a significant role in the sense of agency.

  1. Quantifying cosmic variance

    NASA Astrophysics Data System (ADS)

    Driver, Simon P.; Robotham, Aaron S. G.

    2010-10-01

    We determine an expression for the cosmic variance of any `normal' galaxy survey based on examination of M* +/- 1 mag galaxies in the Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) data cube. We find that cosmic variance will depend on a number of factors principally: total survey volume, survey aspect ratio and whether the area surveyed is contiguous or comprising independent sightlines. As a rule of thumb cosmic variance falls below 10 per cent once a volume of 107h-30.7Mpc3 is surveyed for a single contiguous region with a 1:1 aspect ratio. Cosmic variance will be lower for higher aspect ratios and/or non-contiguous surveys. Extrapolating outside our test region we infer that cosmic variance in the entire SDSS DR7 main survey region is ~7 per cent to z < 0.1. The equation obtained from the SDSS DR7 region can be generalized to estimate the cosmic variance for any density measurement determined from normal galaxies (e.g. luminosity densities, stellar mass densities and cosmic star formation rates) within the volume range 103-107h-30.7Mpc3. We apply our equation to show that two sightlines are required to ensure that cosmic variance is <10 per cent in any ASKAP galaxy survey (divided into Δ z ~ 0.1 intervals, i.e. ~1Gyr intervals for z < 0.5). Likewise 10 MeerKAT sightlines will be required to meet the same conditions. GAMA, VVDS and zCOSMOS all suffer less than 10 per cent cosmic variance (~3-8 per cent) in Δ z intervals of 0.1, 0.25 and 0.5, respectively. Finally we show that cosmic variance is potentially at the 50-70 per cent level, or greater, in the Hubble Space Telescope (HST) Ultra Deep Field depending on assumptions as to the evolution of clustering. 100 or 10 independent sightlines will be required to reduce cosmic variance to a manageable level (<10 per cent) for HST ACS or HST WFC3 surveys, respectively (in Δ z ~ 1 intervals). Cosmic variance is therefore a significant factor in the z > 6 HST studies currently underway.

  2. Producing remote sensing-based emission estimates of prescribed burning in the contiguous United States for the U.S. Environmental Protection Agency 2011 National Emissions Inventory

    NASA Astrophysics Data System (ADS)

    McCarty, J. L.; Pouliot, G. A.; Soja, A. J.; Miller, M. E.; Rao, T.

    2013-12-01

    Prescribed fires in agricultural landscapes generally produce smaller burned areas than wildland fires but are important contributors to emissions impacting air quality and human health. Currently, there are a variety of available satellite-based estimates of crop residue burning, including the NOAA/NESDIS Hazard Mapping System (HMS) the Satellite Mapping Automated Reanalysis Tool for Fire Incident Reconciliation (SMARTFIRE 2), the Moderate Resolution Imaging Spectroradiometer (MODIS) Official Burned Area Product (MCD45A1)), the MODIS Direct Broadcast Burned Area Product (MCD64A1) the MODIS Active Fire Product (MCD14ML), and a regionally-tuned 8-day cropland differenced Normalized Burn Ratio product for the contiguous U.S. The purpose of this NASA-funded research was to refine the regionally-tuned product utilizing higher spatial resolution crop type data from the USDA NASS Cropland Data Layer and burned area training data from field work and high resolution commercial satellite data to improve the U.S. Environmental Protection Agency's (EPA) National Emissions Inventory (NEI). The final product delivered to the EPA included a detailed database of 25 different atmospheric emissions at the county level, emission distributions by crop type and seasonality, and GIS data. The resulting emission databases were shared with the U.S. EPA and regional offices, the National Wildfire Coordinating Group (NWGC) Smoke Committee, and all 48 states in the contiguous U.S., with detailed error estimations for Wyoming and Indiana and detailed analyses of results for Florida, Minnesota, North Dakota, Oklahoma, and Oregon. This work also provided opportunities in discovering the different needs of federal and state partners, including the various geospatial abilities and platforms across the many users and how to incorporate expert air quality, policy, and land management knowledge into quantitative earth observation-based estimations of prescribed fire emissions. Finally, this work created direct communication paths between federal and state partners to the scientists creating the remote sensing-based products, further improving the geospatial products and understanding of air quality impacts of prescribed burning at the state, regional, and national scales.

  3. Performance Evaluation of the Geostationary Synthetic Thinned Array Radiometer (GeoSTAR) Demonstrator Instrument

    NASA Technical Reports Server (NTRS)

    Tanner, Alan B.; Wilson, William J.; Lambrigsten, Bjorn H.; Dinardo, Steven J.; Brown, Shannon T.; Kangaslahti, Pekka P.; Gaier, Todd C.; Ruf, C. S.; Gross, S. M.; Lim, B. H.; hide

    2006-01-01

    The design, error budget, and preliminary test results of a 50-56 GHz synthetic aperture radiometer demonstration system are presented. The instrument consists of a fixed 24-element array of correlation interferometers, and is capable of producing calibrated images with 0.8 degree spatial resolution within a 17 degree wide field of view. This system has been built to demonstrate performance and a design which can be scaled to a much larger geostationary earth imager. As a baseline, such a system would consist of about 300 elements, and would be capable of providing contiguous, full hemispheric images of the earth with 1 Kelvin of radiometric precision and 50 km spatial resolution.

  4. Process for Making a Semiconductor Device with Barrier Film Formation Using a Metal Halide and Products Thereof

    DTIC Science & Technology

    1998-08-20

    structure of the barrier film on an atomic level where the barrier film is comprised of a plurality of contiguous monolayers, while FIG. 7B shows...another embodiment where the barrier film is comprised of a plurality of i contiguous monolayers in which different monolayers thereof are formed... effusion cell, for example a barium fluoride, strontium fluoride or the like effusion cell, is provided at 32, and has a shutter 33. A 15 shutter 35

  5. Users manual for the Automated Performance Test System (APTS)

    NASA Technical Reports Server (NTRS)

    Lane, N. E.; Kennedy, R. S.

    1990-01-01

    The characteristics of and the user information for the Essex Automated Performance Test System (APTS) computer-based portable performance assessment battery are given. The battery was developed to provide a menu of performance test tapping the widest possible variety of human cognitive and motor functions, implemented on a portable computer system suitable for use in both laboratory and field settings for studying the effects of toxic agents and other stressors. The manual gives guidance in selecting, administering and scoring tests from the battery, and reviews the data and studies underlying the development of the battery. Its main emphasis is on the users of the battery - the scientists, researchers and technicians who wish to examine changes in human performance across time or as a function of changes in the conditions under which test data are obtained. First the how to information needed to make decisions about where and how to use the battery is given, followed by the research background supporting the battery development. Further, the development history of the battery focuses largely on the logical framework within which tests were evaluated.

  6. Broadband absorption enhancement in plasmonic nanoshells-based ultrathin microcrystalline-Si solar cells

    NASA Astrophysics Data System (ADS)

    Raja, Waseem; Bozzola, Angelo; Zilio, Pierfrancesco; Miele, Ermanno; Panaro, Simone; Wang, Hai; Toma, Andrea; Alabastri, Alessandro; de Angelis, Francesco; Zaccaria, Remo Proietti

    2016-04-01

    With the objective to conceive a plasmonic solar cell with enhanced photocurrent, we investigate the role of plasmonic nanoshells, embedded within a ultrathin microcrystalline silicon solar cell, in enhancing broadband light trapping capability of the cell and, at the same time, to reduce the parasitic loss. The thickness of the considered microcrystalline silicon (μc-Si) layer is only ~1/6 of conventional μc-Si based solar cells while the plasmonic nanoshells are formed by a combination of silica and gold, respectively core and shell. We analyze the cell optical response by varying both the geometrical and optical parameters of the overall device. In particular, the nanoshells core radius and metal thickness, the periodicity, the incident angle of the solar radiation and its wavelength are varied in the widest meaningful ranges. We further explain the reason for the absorption enhancement by calculating the electric field distribution associated to resonances of the device. We argue that both Fabry-Pérot-like and localized plasmon modes play an important role in this regard.

  7. Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

    ClinicalTrials.gov

    2015-06-03

    Hematopoietic/Lymphoid Cancer; Accelerated Phase Chronic Myelogenous Leukemia; Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Aplastic Anemia; Atypical Chronic Myeloid Leukemia, BCR-ABL Negative; Blastic Phase Chronic Myelogenous Leukemia; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Cytomegalovirus Infection; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Intraocular Lymphoma; Isolated Plasmacytoma of Bone; Mast Cell Leukemia; Meningeal Chronic Myelogenous Leukemia; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Primary Systemic Amyloidosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Secondary Myelofibrosis; Splenic Marginal Zone Lymphoma; Stage 0 Chronic Lymphocytic Leukemia; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma; T-cell Large Granular Lymphocyte Leukemia; Waldenstrom Macroglobulinemia

  8. Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant

    ClinicalTrials.gov

    2015-08-12

    Adult Grade III Lymphomatoid Granulomatosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Grade III Lymphomatoid Granulomatosis; Childhood Immunoblastic Large Cell Lymphoma; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Hairy Cell Leukemia; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Hodgkin Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Hodgkin Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; T-cell Large Granular Lymphocyte Leukemia; Testicular Lymphoma; Waldenström Macroglobulinemia

  9. China Report, Red Flag, Number 8, 16 April 1982.

    DTIC Science & Technology

    1982-06-16

    national industries as quickly as possible through foreign economic relations and by drawing support from foreign capital and advanced technology. Only...that are importing consumer goods without permission are, in fact, very harmful and shameful activities that impair our national industry . It is an...important principle that we must pay close attention to protecting our national industry . We must make the widest possible use of those daily

  10. The NASA Technical Report Server

    NASA Astrophysics Data System (ADS)

    Nelson, M. L.; Gottlich, G. L.; Bianco, D. J.; Paulson, S. S.; Binkley, R. L.; Kellogg, Y. D.; Beaumont, C. J.; Schmunk, R. B.; Kurtz, M. J.; Accomazzi, A.; Syed, O.

    The National Aeronautics and Space Act of 1958 established the National Aeronautics and Space Administration (NASA) and charged it to "provide for the widest practicable and appropriate dissemination of information concerning...its activities and the results thereof". The search for innovative methods to distribute NASA's information led a grass-roots team to create the NASA Technical Report Server (NTRS), which uses the World Wide Web and other popular Internet-based information systems .

  11. Elastic Buckling under Combined Stresses of Flat Plates with Integral Waffle-Like Stiffening

    NASA Technical Reports Server (NTRS)

    Dow, Norris F.; Levin, L. Ross; Troutman, John L.

    1953-01-01

    Theory and experiment were compared and found in good agreement for the elastic Buckling under combined stresses of long flat plates with integral waffle-like stiffening in a variety of configurations. For such flat plates, 45deg waffle stiffening was found to be the most effective of the configurations for the proportions considered over the widest range of combinations of compression and shear.

  12. Elastic Buckling Under Combined Stresses of Flat Plates with Integral Waffle-like Stiffening

    NASA Technical Reports Server (NTRS)

    Dow, Norris F; Levin, L Ross; Troutman, John L

    1954-01-01

    Theory and experiment were compared and found in good agreement for the elastic buckling under combined stresses of long flat plates with integral waffle-like stiffening in a variety of configurations. For such flat plates, 45 degree waffle stiffening was found to be the most effective of the configurations for the proportions considered over the widest range of combinations of compression and shear.

  13. Chandra survey in the AKARI North Ecliptic Pole Deep Field - I. X-ray data, point-like source catalogue, sensitivity maps, and number counts

    NASA Astrophysics Data System (ADS)

    Krumpe, M.; Miyaji, T.; Brunner, H.; Hanami, H.; Ishigaki, T.; Takagi, T.; Markowitz, A. G.; Goto, T.; Malkan, M. A.; Matsuhara, H.; Pearson, C.; Ueda, Y.; Wada, T.

    2015-01-01

    We present data products from the 300 ks Chandra survey in the AKARI North Ecliptic Pole Deep Field. This field has a unique set of nine-band infrared photometry covering 2-24 μm from the AKARI Infrared Camera, including mid-infrared (MIR) bands not covered by Spitzer. The survey is one of the deepest ever achieved at ˜15 μm, and is by far the widest among those with similar depths in the MIR. This makes this field unique for the MIR-selection of AGN at z ˜ 1. We design a source detection procedure, which performs joint maximum likelihood PSF (point spread function) fits on all of our 15 mosaicked Chandra pointings covering an area of 0.34 deg2. The procedure has been highly optimized and tested by simulations. We provide a point source catalogue with photometry and Bayesian-based 90 per cent confidence upper limits in the 0.5-7, 0.5-2, 2-7, 2-4, and 4-7 keV bands. The catalogue contains 457 X-ray sources and the spurious fraction is estimated to be ˜1.7 per cent. Sensitivity and 90 per cent confidence upper flux limits maps in all bands are provided as well. We search for optical-MIR counterparts in the central 0.25 deg2, where deep Subaru Suprime-Cam multiband images exist. Among the 377 X-ray sources detected there, ˜80 per cent have optical counterparts and ˜60 per cent also have AKARI MIR counterparts. We cross-match our X-ray sources with MIR-selected AGN from Hanami et al. Around 30 per cent of all AGN that have MIR SEDs purely explainable by AGN activity are strong Compton-thick AGN candidates.

  14. Spatiotemporal Interpolation Methods for the Application of Estimating Population Exposure to Fine Particulate Matter in the Contiguous U.S. and a Real-Time Web Application.

    PubMed

    Li, Lixin; Zhou, Xiaolu; Kalo, Marc; Piltner, Reinhard

    2016-07-25

    Appropriate spatiotemporal interpolation is critical to the assessment of relationships between environmental exposures and health outcomes. A powerful assessment of human exposure to environmental agents would incorporate spatial and temporal dimensions simultaneously. This paper compares shape function (SF)-based and inverse distance weighting (IDW)-based spatiotemporal interpolation methods on a data set of PM2.5 data in the contiguous U.S. Particle pollution, also known as particulate matter (PM), is composed of microscopic solids or liquid droplets that are so small that they can get deep into the lungs and cause serious health problems. PM2.5 refers to particles with a mean aerodynamic diameter less than or equal to 2.5 micrometers. Based on the error statistics results of k-fold cross validation, the SF-based method performed better overall than the IDW-based method. The interpolation results generated by the SF-based method are combined with population data to estimate the population exposure to PM2.5 in the contiguous U.S. We investigated the seasonal variations, identified areas where annual and daily PM2.5 were above the standards, and calculated the population size in these areas. Finally, a web application is developed to interpolate and visualize in real time the spatiotemporal variation of ambient air pollution across the contiguous U.S. using air pollution data from the U.S. Environmental Protection Agency (EPA)'s AirNow program.

  15. Spatiotemporal Interpolation Methods for the Application of Estimating Population Exposure to Fine Particulate Matter in the Contiguous U.S. and a Real-Time Web Application

    PubMed Central

    Li, Lixin; Zhou, Xiaolu; Kalo, Marc; Piltner, Reinhard

    2016-01-01

    Appropriate spatiotemporal interpolation is critical to the assessment of relationships between environmental exposures and health outcomes. A powerful assessment of human exposure to environmental agents would incorporate spatial and temporal dimensions simultaneously. This paper compares shape function (SF)-based and inverse distance weighting (IDW)-based spatiotemporal interpolation methods on a data set of PM2.5 data in the contiguous U.S. Particle pollution, also known as particulate matter (PM), is composed of microscopic solids or liquid droplets that are so small that they can get deep into the lungs and cause serious health problems. PM2.5 refers to particles with a mean aerodynamic diameter less than or equal to 2.5 micrometers. Based on the error statistics results of k-fold cross validation, the SF-based method performed better overall than the IDW-based method. The interpolation results generated by the SF-based method are combined with population data to estimate the population exposure to PM2.5 in the contiguous U.S. We investigated the seasonal variations, identified areas where annual and daily PM2.5 were above the standards, and calculated the population size in these areas. Finally, a web application is developed to interpolate and visualize in real time the spatiotemporal variation of ambient air pollution across the contiguous U.S. using air pollution data from the U.S. Environmental Protection Agency (EPA)’s AirNow program. PMID:27463722

  16. Modulation of early cortical processing during divided attention to non-contiguous locations.

    PubMed

    Frey, Hans-Peter; Schmid, Anita M; Murphy, Jeremy W; Molholm, Sophie; Lalor, Edmund C; Foxe, John J

    2014-05-01

    We often face the challenge of simultaneously attending to multiple non-contiguous regions of space. There is ongoing debate as to how spatial attention is divided under these situations. Whereas, for several years, the predominant view was that humans could divide the attentional spotlight, several recent studies argue in favor of a unitary spotlight that rhythmically samples relevant locations. Here, this issue was addressed by the use of high-density electrophysiology in concert with the multifocal m-sequence technique to examine visual evoked responses to multiple simultaneous streams of stimulation. Concurrently, we assayed the topographic distribution of alpha-band oscillatory mechanisms, a measure of attentional suppression. Participants performed a difficult detection task that required simultaneous attention to two stimuli in contiguous (undivided) or non-contiguous parts of space. In the undivided condition, the classic pattern of attentional modulation was observed, with increased amplitude of the early visual evoked response and increased alpha amplitude ipsilateral to the attended hemifield. For the divided condition, early visual responses to attended stimuli were also enhanced, and the observed multifocal topographic distribution of alpha suppression was in line with the divided attention hypothesis. These results support the existence of divided attentional spotlights, providing evidence that the corresponding modulation occurs during initial sensory processing time-frames in hierarchically early visual regions, and that suppressive mechanisms of visual attention selectively target distracter locations during divided spatial attention. © 2014 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  17. Evidence for increasingly variable Palmer Drought Severity Index in the United States since 1895.

    PubMed

    Rayne, Sierra; Forest, Kaya

    2016-02-15

    Annual and summertime trends towards increasingly variable values of the Palmer Drought Severity Index (PDSI) over a sub-decadal period (five years) were investigated within the contiguous United States between 1895 and the present. For the contiguous United States as a whole, there is a significant increasing trend in the five-year running minimum-maximum ranges for the annual PDSI (aPDSI5 yr(min|max, range)). During this time frame, the average aPDSI5 yr(min|max, range) has increased by about one full unit, indicating a substantial increase in drought variability over short time scales across the United States. The end members of the running aPDSI5 yr(min|max, range) highlight even more rapid changes in the drought index variability within the past 120 years. This increasing variability in the aPDSI5 yr(min|max, range) is driven primarily by changes taking place in the Pacific and Atlantic Ocean coastal climate regions, climate regions which collectively comprise one-third the area of the contiguous United States. Similar trends were found for the annual and summertime Palmer Hydrological Drought Index (PHDI), the Palmer Modified Drought Index (PMDI), and the Palmer Z Index (PZI). Overall, interannual drought patterns in the contiguous United States are becoming more extreme and difficult to predict, posing a challenge to agricultural and other water-resource related planning efforts. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Effects of income and urban form on urban NO2: global evidence from satellites.

    PubMed

    Bechle, Matthew J; Millet, Dylan B; Marshall, Julian D

    2011-06-01

    Urban air pollution is among the top 15 causes of death and disease worldwide, and a problem of growing importance with a majority of the global population living in cities. A important question for sustainable development is to what extent urban design can improve or degrade the environment and public health. We investigate relationships between satellite-derived estimates of nitrogen dioxide concentration (NO(2), a key component of urban air pollution) and urban form for 83 cities globally. We find a parsimonious yet powerful relationship (model R(2) = 0.63), using as predictors population, income, urban contiguity, and meteorology. Cities with highly contiguous built-up areas have, on average, lower urban NO(2) concentrations (a one standard deviation increase in contiguity is associated with a 24% decrease in average NO(2) concentration). More-populous cities tend to have worse air quality, but the increase in NO(2) associated with a population increase of 10% may be offset by a moderate increase (4%) in urban contiguity. Urban circularity ("compactness") is not a statistically significant predictor of NO(2) concentration. Although many factors contribute to urban air pollution, our findings suggest that antileapfrogging policies may improve air quality. We find that urban NO(2) levels vary nonlinearly with income (Gross Domestic Product), following an "environmental Kuznets curve"; we estimate that if high-income countries followed urban pollution-per-income trends observed for low-income countries, NO(2) concentrations in high-income cities would be ∼10× larger than observed levels.

  19. Functional evaluation and rehabilitation engineering.

    PubMed

    Aliverti, Andrea; Frigo, C; Andreoni, G; Baroni, G; Bonarini, A; Cerveri, P; Crivellini, M; Dellaca, R; Ferrigno, G; Galli, M; Pedrocchi, A; Rodano, R; Santambrogio, G C; Tognola, G; Pedotti, A

    2011-01-01

    Life is complex and all about movement, which allows us to interact with the environment and communicate with each other. The human nervous system is capable of performing a simultaneous and integrated control of 100-150 mechanical degrees of freedom of movement in the body via tensions generated by about 700 muscles. In its widest context, movement is carried out by a sensory motor system comprising multiple sensors (visual,auditory, and proprioceptive),multiple actuators (muscles acting on the skeletal system),and an intermediary processor that can be summarized as a multiple-input–multiple-output nonlinear dynamic time-varying control system. This grand control system is capable of responding with remarkable accuracy,speed, appropriateness,versatility, and adaptability to a wide spectrum of continuous and discrete stimuli and conditions and is certainly orders of magnitude more complex and sophisticated than the most advanced robotic systems currently available. In the last decades,a great deal of research has been carried out in the fields of functional evaluation of human performance and rehabilitation engineering. These fields combine knowledge, concepts, and methods from across many disciplines (e.g., biomechanics,neuroscience, and physiology), with the aim of developing apparatuses and methods fort he measurement and analysis of complex sensory motor performance and the ultimate goal of enhancing the execution of different tasks in both healthy people and persons with reduced capabilities from different causes (injury, disease, amputation,and neural degeneration).

  20. Jupiter and Its Galilean Satellites

    NASA Technical Reports Server (NTRS)

    McGrath, Melissa A.

    2012-01-01

    Jupiter is one of the two most studied planets other than Earth in our Solar System. It is the largest, fastest rotating, has the strongest magnetic field, and an incredibly diverse set of satellites, most prominent of which are the four Galilean satellites discovered in 1610. Io, Europa, Ganymede and Callisto encompass some of the most bizarre environments known in the solar system, from Io, the most volcanically active and perhaps the most inhospitable body known, to Europa, currently thought to be the most likely extraterrestrial abode for habitability, to Ganymede, which is larger than Mercury, and Callisto, which has the oldest surface known in the solar system with the widest array of crater morphologies known. One of the premier areas of scientific return in solar system research in the past 15 years, due in large part to the Galileo mission and observations by the Hubble Space Telescope, has been a remarkable increase in our knowledge about these satellites. Discoveries have been made of tenuous molecular oxygen atmospheres on Europa and Ganymede, a magnetic field and accompanying auroral emissions at the poles of Ganymede, and of ozone and sulfur dioxide embedded in the surfaces of Europa, Ganymede and Callisto. Io's unusual sulfur dioxide atmosphere, including its volcanic plumes and strong electrodynamic interaction with magnetospheric plasma, has finally been quantitatively characterized. This talk will present highlights from the recent discoveries and advances in our understanding of these fascinating objects.

  1. SWAP OBSERVATIONS OF THE LONG-TERM, LARGE-SCALE EVOLUTION OF THE EXTREME-ULTRAVIOLET SOLAR CORONA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seaton, Daniel B.; De Groof, Anik; Berghmans, David

    The Sun Watcher with Active Pixels and Image Processing (SWAP) EUV solar telescope on board the Project for On-Board Autonomy 2 spacecraft has been regularly observing the solar corona in a bandpass near 17.4 nm since 2010 February. With a field of view of 54 × 54 arcmin, SWAP provides the widest-field images of the EUV corona available from the perspective of the Earth. By carefully processing and combining multiple SWAP images, it is possible to produce low-noise composites that reveal the structure of the EUV corona to relatively large heights. A particularly important step in this processing was tomore » remove instrumental stray light from the images by determining and deconvolving SWAP's point-spread function from the observations. In this paper, we use the resulting images to conduct the first-ever study of the evolution of the large-scale structure of the corona observed in the EUV over a three year period that includes the complete rise phase of solar cycle 24. Of particular note is the persistence over many solar rotations of bright, diffuse features composed of open magnetic fields that overlie polar crown filaments and extend to large heights above the solar surface. These features appear to be related to coronal fans, which have previously been observed in white-light coronagraph images and, at low heights, in the EUV. We also discuss the evolution of the corona at different heights above the solar surface and the evolution of the corona over the course of the solar cycle by hemisphere.« less

  2. Advances in handheld FT-IR instrumentation

    NASA Astrophysics Data System (ADS)

    Arnó, Josep; Cardillo, Len; Judge, Kevin; Frayer, Maxim; Frunzi, Michael; Hetherington, Paul; Levy, Dustin; Oberndorfer, Kyle; Perec, Walter; Sauer, Terry; Stein, John; Zuidema, Eric

    2012-06-01

    FT-IR spectroscopy is the technology of choice to identify solid and liquid phase unknown samples. The challenges of ConOps (Concepts of Operation) in emergency response and military field applications require a significant redesign of the stationary FT-IR bench-top instruments typically used in laboratories. Specifically, field portable units require high levels of resistance against mechanical shock and chemical attack, ease of use in restrictive gear, quick and easy interpretation of results, and reduced size. In the last 20 years, FT-IR instruments have been re-engineered to fit in small suitcases for field portable use and recently further miniaturized for handheld operation. This article introduces the advances resulting from a project designed to overcome the challenges associated with miniaturizing FT-IR instruments. The project team developed a disturbance-corrected permanently aligned cube corner interferometer for improved robustness and optimized opto-mechanical design to maximize optical throughput and signal-to-noise ratios. Thermal management and heat flow were thoroughly modeled and studied to isolate sensitive components from heat sources and provide the widest temperature operation range. Similarly, extensive research on mechanical designs and compensation techniques to protect against shock and vibration will be discussed. A user interface was carefully created for military and emergency response applications to provide actionable information in a visual, intuitive format. Similar to the HazMatID family of products, state-of-the-art algorithms were used to quickly identify the chemical composition of complex samples based on the spectral information. This article includes an overview of the design considerations, tests results, and performance validation of the mechanical ruggedness, spectral, and thermal performance.

  3. Method for promoting specific alignment of short oligonucleotides on nucleic acids

    DOEpatents

    Studier, F. William; Kieleczawa, Jan; Dunn, John J.

    1996-01-01

    Disclosed is a method for promoting specific alignment of short oligonucleotides on a nucleic acid polymer. The nucleic acid polymer is incubated in a solution containing a single-stranded DNA-binding protein and a plurality of oligonucleotides which are perfectly complementary to distinct but adjacent regions of a predetermined contiguous nucleotide sequence in the nucleic acid polymer. The plurality of oligonucleotides anneal to the nucleic acid polymer to form a contiguous region of double stranded nucleic acid. Specific application of the methods disclosed include priming DNA synthesis and template-directed ligation.

  4. CRREL’s First 25 Years 1961-1986

    DTIC Science & Technology

    1986-06-01

    complete cooper.ation to the people of CRREL. It was necessary to re- place most of the electrical facilities and wiring in the new building. And...missile defense antennas. The CRREL researchers found that electrical resistance heating was the method that proved effective under the widest variety of...crew was lost in the crash. In charge of the CRREL on-site research was Guenther Frankenstein , who calculated the weight of equipment that the sea

  5. Design Considerations for Siting Grade Control Structures

    DTIC Science & Technology

    2001-12-01

    require consideration before siting grade control structures. In the widest sense, the term grade control can be applied to any alteration in the...control structures. There are two basic types of grade control structures. One type can be referred to as a bed control structure as it is designed to...provide a hard point in the streambed that is capable of resisting the erosive forces of the degradational zone. The second type can be referred to

  6. US Industrial Base Dependence/Vulnerability. Phase 2. Analysis

    DTIC Science & Technology

    1987-11-01

    widest range of prospec- tive bidders on his program--ino IudIng Japanese, Israeli, Korean, Brazilian, et cetera. The program manager clearly cannot...nuclear weapons did not do away with the previous force structure), or 2) a major war (we did get rid of the horse cavalry in WWII). However, it is...ion arrangements with NATO Allies. a program manager would seek the bidders on his program--I no Iuding Mian, et cetera. The program

  7. General Purpose Force Capability; the Challenge of Versatility and Achieving Balance Along the Widest Possible Spectrum of Conflict

    DTIC Science & Technology

    2010-04-01

    billion dollar systems and platforms. In the looming era of limited resources for defense spending, military and civilian leaders light of recent...conventional systems .”28 Finding the Proper Balance Abandoning our military superiority in conventional warfare would b On the other hand, swinging...Defense Strategy published in March 2005. The 2005 version of the National Defense Strategy recognized that, “we are confronting fundamentally

  8. Graphs and matroids weighted in a bounded incline algebra.

    PubMed

    Lu, Ling-Xia; Zhang, Bei

    2014-01-01

    Firstly, for a graph weighted in a bounded incline algebra (or called a dioid), a longest path problem (LPP, for short) is presented, which can be considered the uniform approach to the famous shortest path problem, the widest path problem, and the most reliable path problem. The solutions for LPP and related algorithms are given. Secondly, for a matroid weighted in a linear matroid, the maximum independent set problem is studied.

  9. Ten-Year Results in a Cottonwood Plantation Spacing Study

    Treesearch

    R. M. Krinard; Robert L. Johnson

    1975-01-01

    During the first 10 years, unthinned cottonwood planted at four spacings grew from 2.8 to 3.4 cords per acre per year in trees 5.0 inches in d.b.h. and larger. Two basal area controlled thinning treatments did not increase yields. Initial spacings were 4 by 9, 8 by 9, 12 by 12, and 16 by 18 feet on Commerce-Convent soils. Only trees at the widest spacing averaged an...

  10. VizieR Online Data Catalog: PAndAS view of Andromeda satellites. II. (Martin+, 2016)

    NASA Astrophysics Data System (ADS)

    Martin, N. F.; Ibata, R. A.; Lewis, G. F.; McConnachie, A.; Babul, A.; Bate, N. F.; Bernard, E.; Chapman, S. C.; Collins, M. M. L.; Conn, A. R.; Crnojevic, D.; Fardal, M. A.; Ferguson, A. M. N.; Irwin, M.; Mackey, A. D.; McMonigal, B.; Navarro, J. F.; Rich, R. M.

    2017-04-01

    The specifics of the design, acquisition, reduction, and calibration of the Pan-Andromeda Archaeological Survey (PAndAS) survey have been explained in detail in previous contributions from our collaboration (e.g., Ibata+ 2014ApJ...780..128I). This Canada-France-Hawaii Telescope (CFHT) Large Program was built on two previous CFHT surveys led by R. Ibata and A. McConnachie (Ibata+ 2007ApJ...671.1591I; McConnachie+ 2008ApJ...688.1009M), which were further complemented by ~230hr of observation with the same wide-field imager, MegaCam, in order to cover a contiguous region of ~390deg2 within ~150kpc of M31 and ~50kpc of its companion M33. (3 data files).

  11. Nuclear pulse. II - Ensuring delivery of the doomsday signal

    NASA Astrophysics Data System (ADS)

    Broad, W. J.

    1981-06-01

    The ability of the communications systems on which U.S. strategic forces depend to survive the electromagnetic pulse (EMP) effects of a nuclear blast in the upper atmosphere is examined. It is shown that the Bell system telephone network, Autovon, on which much military communication presently depends, is especially vulnerable to EMP; while satellite and microwave communications networks are expected to be more resistant to attack. Satellites are, though, vulnerable to killer-satellite attack. Much promise is seen in the conversion of ground communications links to fiber-optic form, which is inherently highly resistant to EMP. A nuclear bomb detonated 200 miles above Nebraska would affect communications equipment throughout the contiguous U.S. with peak fields of 500,000 volts/meter.

  12. Spin systems and Political Districting Problem

    NASA Astrophysics Data System (ADS)

    Chou, Chung-I.; Li, Sai-Ping

    2007-03-01

    The aim of the Political Districting Problem is to partition a territory into electoral districts subject to some constraints such as contiguity, population equality, etc. In this paper, we apply statistical physics methods to Political Districting Problem. We will show how to transform the political problem to a spin system, and how to write down a q-state Potts model-like energy function in which the political constraints can be written as interactions between sites or external fields acting on the system. Districting into q voter districts is equivalent to finding the ground state of this q-state Potts model. Searching for the ground state becomes an optimization problem, where optimization algorithms such as the simulated annealing method and Genetic Algorithm can be employed here.

  13. Wall thickness measuring method and apparatus

    DOEpatents

    Salzer, L.J.; Bergren, D.A.

    1987-10-06

    An apparatus for measuring the wall thickness of a nonmagnetic article having a housing supporting a magnet and a contiguous supporting surface. The tubular article and the housing are releasably secured to the supporting surface and a support member of an optical comparator, respectively. To determine the wall thickness of the article at a selected point, a magnetically responsive ball is positioned within the tubular article over said point and retained therein by means of a magnetic field produced by the magnet. Thereafter, an optical comparator is employed to project a magnified image of the ball on a screen and the wall thickness at the selected point is calculated by using a ball surface measurement taken with the comparator in conjunction with a previously determined base line measurement.

  14. Atmospheric tomography using a fringe pattern in the sodium layer.

    PubMed

    Baharav, Y; Ribak, E N; Shamir, J

    1994-02-15

    We wish to measure and separate the contribution of atmospheric turbulent layers for multiconjugate adaptive optics. To this end, we propose to create a periodic fringe pattern in the sodium layer and image it with a modified Hartmann sensor. Overlapping sections of the fringes are imaged by a lenslet array onto contiguous areas in a large-format camera. Low-layer turbulence causes an overall shift of the fringe pattern in each lenslet, and high-attitude turbulence results in internal deformations in the pattern. Parallel Fourier analysis permits separation of the atmospheric layers. Two mirrors, one conjugate to a ground layer and the other conjugate to a single high-altitude layer, are shown to widen the field of view significantly compared with existing methods.

  15. Wall thickness measuring method and apparatus

    DOEpatents

    Salzer, Leander J.; Bergren, Donald A.

    1989-01-01

    An apparatus for measuring the wall thickness of a nonmagnetic article having a housing supporting a magnet and a contiguous supporting surface. The tubular article and the housing are releasably secured to the supporting surface and a support member of an optical comparator, respectively. To determine the wall thickness of the article at a selected point, a magnetically responsive ball is positioned within the tubular article over said point and retained therein by means of a magnetic field produced by the magnet. Thereafter, an optical comparator is employed to project a magnified image of the ball on a screen and the wall thickness at the selected point is calculated by using a ball surface measurement taken with the comparator in conjunction with a previously determined base line measurement.

  16. Recent Advances in Experimental Whole Genome Haplotyping Methods

    PubMed Central

    Huang, Mengting; Lu, Zuhong

    2017-01-01

    Haplotype plays a vital role in diverse fields; however, the sequencing technologies cannot resolve haplotype directly. Pioneers demonstrated several approaches to resolve haplotype in the early years, which was extensively reviewed. Since then, numerous methods have been developed recently that have significantly improved phasing performance. Here, we review experimental methods that have emerged mainly over the past five years, and categorize them into five classes according to their maximum scale of contiguity: (i) encapsulation, (ii) 3D structure capture and construction, (iii) compartmentalization, (iv) fluorography, (v) long-read sequencing. Several subsections of certain methods are attached to each class as instances. We also discuss the relative advantages and disadvantages of different classes and make comparisons among representative methods of each class. PMID:28891974

  17. Opening Talk: Opening Talk

    NASA Astrophysics Data System (ADS)

    Doebner, H.-D.

    2008-02-01

    Ladies and Gentlemen Dear Friends and Colleagues I welcome you at the 5th International Symposium `Quantum Theory and Symmetries, QTS5' in Valladolid as Chairman of the Conference Board of this biannual series. The aim of the series is to arrange an international meeting place for scientists working in theoretical and mathematical physics, in mathematics, in mathematical biology and chemistry and in other sciences for the presentation and discussion of recent developments in connection with quantum physics and chemistry, material science and related further fields, like life sciences and engineering, which are based on mathematical methods which can be applied to model and to understand microphysical and other systems through inherent symmetries in their widest sense. These systems include, e.g., foundations and extensions of quantum theory; quantum probability; quantum optics and quantum information; the description of nonrelativistic, finite dimensional and chaotic systems; quantum field theory, particle physics, string theory and quantum gravity. Symmetries in their widest sense describe properties of a system which could be modelled, e.g., through geometry, group theory, topology, algebras, differential geometry, noncommutative geometry, functional analysis and approximation methods; numerical evaluation techniques are necessary to connect such symmetries with experimental results. If you ask for a more detailed characterisation of this notion a hand waving indirect answer is: Collect titles and contents of the contributions of the proceedings of QTS4 and get a characterisation through semantic closure. Quantum theory and its Symmetries was and is a diversified and rapidly growing field. The number of and the types of systems with an internal symmetry and the corresponding mathematical models develop fast. This is reflected in the content of the five former international symposia of this series: The first symposium, QTS1-1999, was organized in Goslar (Germany) with 170 participants and 89 contributions in the proceedings; it was centred on the foundations and extensions of quantum theory, on quantisation methods and on q-algebras. In QTS2-2001 in Cracow (Poland) with 175 participants and 81 contributions; the main topics were applications of quantum mechanics, representations of algebras and group theoretical techniques in physics. In the symposium QTS3-2003 in Cincinnati (USA) with 145 participants and 92 contributions, quantum field theory, loop quantum gravity, string and brane theory was discussed. The focus in QTS4-2005 in Varna (Bulgaria) with 228 participant and 105 contributions, was on conformal field theory, quantum gravity, noncommutative geometry and quantum groups. Three proceedings volumes were published with World Scientific and one volume with Heron Press. The promising and interesting programme for QTS5-2007 in Valladolid (Spain) attracted more than 200 participants; the contributions will be published in a special issue of Journal of Physics A: Mathematical and Theoretical and a volume of Journal of Physics: Conference Series. This shows the wide scope of symmetry in connection with quantum physics and related sciences. In the background of the symposia series is the Conference Board with presently 13 members. The Board encourages scientists and Institutions to present detailed proposals for a QTS symposium; it agrees to one proposal and is prepared to assist in matters of organisation; the local organisers are responsible for the scientific programme and for the organisation, including the budget. The Board decided that the next symposium QTS6 will be held 2009 at the University of Kentucky in Lexington (USA); Alan Shapere is the chairman of the Local Organizing committee. In the name of all of you I express my appreciation and my thanks to the members of the Local Organizing Committee of QTS5, especially to Mariano del Olmo. The programme is outstanding; it covers recent and new developments in our field. The organization is very effective and complete. We have all the necessary condition for a successful and smooth meeting. Thank you again Mariano. H-D Doebner Chairman of the Conference Board of QTS5

  18. Estimating Per-Pixel GPP of the Contiguous USA Directly from MODIS EVI Data

    NASA Astrophysics Data System (ADS)

    Rahman, A. F.; Sims, D. A.; El-Masri, B. Z.; Cordova, V. D.

    2005-12-01

    We estimated gross primary production (GPP) of the contiguous USA using enhanced vegetation index (EVI) data from NASA's moderate resolution imaging spectroradiometer (MODIS). Based on recently published values of correlation coefficients between EVI and GPP of North American vegetations, we derived GPP maps of the contiguous USA for 2001-2004, which included one La Nina year and three moderately El Nino years. The product was a truly per-pixel GPP estimate (named E-GPP), in contrast to the pseudo-continuous MOD17, the standard MODIS GPP product. We compared E-GPP with fine-scale experimental GPP data and MOD17 estimates from three Bigfoot experimental sites, and also with MOD17 estimates from the whole contiguous USA for the above-mentioned four years. For each of the '7 by 7' km Bigfoot experimental sites, E-GPP was able to track the primary production activity during the green-up period while MOD17 failed to do so. The E-GPP estimates during peak production season were similar to those from Bigfoot and MOD17 for most vegetation types except for the deciduous types, where it was lower. Annual E-GPP of the Bigfoot sites compared well with Bigfoot experimental GPP (r = 0.71) and MOD17 (r = 0.78). But for the contiguous USA for 2001-2004, annual E-GPP showed disagreement with MOD17 in both magnitude and seasonal trends for deciduous forests and grass lands. In this study we explored the reasons for this mismatch between E-GPP and MOD17 and also analyzed the uncertainties in E-GPP across multiple spatial scales. Our results show that the E-GPP, based on a simple regression model, can work as a robust alternative to MOD17 for large-area annual GPP estimation. The relative advantages of E-GPP are that it is truly per-pixel, solely dependent on remotely sensed data that is routinely available from NASA, easy to compute and has the potential of being used as an operational product.

  19. Considerations for monitoring water quality of the Schenectady aquifer, Schenectady County, New York

    USGS Publications Warehouse

    Allen, R.V.; Waller, Roger Milton

    1981-01-01

    Six public water-supply systems in Schenectady County, N.Y., obtain water from sand and gravel units that form a more or less continuous aquifer system contiguous to the Mohawk River. The aquifer is under water-table conditions and in hydraulic contact with the river, so that pumping wells induces recharge from the river. Direct recharge to the aquifer from precipitation and runoff occurs throughout the valley floor. Chemical analyses since 1972 have indicated no water-quality deterioration from toxic substances, including pesticides. Geohydrologic conditions at each of the six well fields were evaluated to determine the feasibility of a monitoring system to provide warning of contamination before it reaches a pumping center. Potential contamination sources in the area are landfills, gravel pits, industrial sites, and transportation corridors. Only two of the well fields have wells that could be used for monitoring; at most sites, two or more wells would need to be installed to provide minimal means of detecting contaminants migrating toward a pumping center. (USGS)

  20. High temperature electrons exhausted from rf plasma sources along a magnetic nozzle

    NASA Astrophysics Data System (ADS)

    Takahashi, Kazunori; Akahoshi, Hikaru; Charles, Christine; Boswell, Rod W.; Ando, Akira

    2017-08-01

    Two dimensional profiles of electron temperature are measured inside and downstream of a radiofrequency plasma thruster source having a magnetic nozzle and being immersed in vacuum. The temperature is estimated from the slope of the fully swept I-V characteristics of a Langmuir probe acquired at each spatial position and with the assumption of a Maxwellian distribution. The results show that the peripheral high temperature electrons in the magnetic nozzle originate from the upstream antenna location and are transported along the "connecting" magnetic field lines. Two-dimensional measurements of electron energy probability functions are also carried out in a second simplified laboratory device consisting of the source contiguously connected to the diffusion chamber: again the high temperature electrons are detected along the magnetic field lines intersecting the wall at the antenna location, even when the antenna location is shifted along the main axis. These results demonstrate that the peripheral energetic electrons in the magnetic nozzle mirror those created in the source tube.

  1. Magnetic thin-film split-domain current sensor-recorder

    DOEpatents

    Hsieh, Edmund J.

    1979-01-01

    A sensor-recorder for recording a representation of the direction and peak amplitude of a transient current. A magnetic thin film is coated on a glass substrate under the influence of a magnetic field so that the finished film is magnetically uniaxial and anisotropic. The film is split into two oppositely magnetized contiguous domains with a central boundary by subjecting adjacent portions of the film simultaneously to magnetic fields that are opposed 180.degree.. With the split-domain sensor-recorder placed with the film plane and domain boundary either perpendicular or parallel to the expected conductive path of a transient current, the occurrence of the transient causes switching of a portion of one domain to the direction of the other domain. The amount of the switched domain portion is indicative of the amplitude of the peak current of the transient, while the particular domain that is switched is indicative of the direction of the current. The resulting domain patterns may be read with a passive magnetic tape viewer.

  2. Long-Term Monitoring of Desert Land and Natural Resources and Application of Remote Sensing Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hamada, Yuki; Rollins, Katherine E.

    2016-11-01

    Monitoring environmental impacts over large, remote desert regions for long periods of time can be very costly. Remote sensing technologies present a promising monitoring tool because they entail the collection of spatially contiguous data, automated processing, and streamlined data analysis. This report provides a summary of remote sensing products and refinement of remote sensing data interpretation methodologies that were generated as part of the U.S. Department of the Interior Bureau of Land Management Solar Energy Program. In March 2015, a team of researchers from Argonne National Laboratory (Argonne) collected field data of vegetation and surface types from more than 5,000more » survey points within the eastern part of the Riverside East Solar Energy Zone (SEZ). Using the field data, remote sensing products that were generated in 2014 using very high spatial resolution (VHSR; 15 cm) multispectral aerial images were validated in order to evaluate potential refinements to the previous methodologies to improve the information extraction accuracy.« less

  3. The Oxford SWIFT Spectrograph: first commissioning and on-sky results

    NASA Astrophysics Data System (ADS)

    Thatte, Niranjan; Tecza, Mathias; Clarke, Fraser; Goodsall, Timothy; Fogarty, Lisa; Houghton, Ryan; Salter, Graeme; Scott, Nicholas; Davies, Roger L.; Bouchez, Antonin; Dekany, Richard

    2010-07-01

    The Oxford SWIFT spectrograph, an I & z band (6500-10500 A) integral field spectrograph, is designed to operate as a facility instrument at the 200 inch Hale Telescope on Palomar Mountain, in conjunction with the Palomar laser guide star adaptive optics system PALAO (and its upgrade to PALM3000). SWIFT provides spectra at R(≡λ/▵λ)~4000 of a contiguous two-dimensional field, 44 x 89 spatial pixels (spaxels) in size, at spatial scales of 0.235", 0.16", and 0.08" per spaxel. It employs two 250μm thick, fully depleted, extremely red sensitive 4k X 2k CCD detector arrays (manufactured by LBNL) that provide excellent quantum efficiency out to 1000 nm. We describe the commissioning observations and present the measured values of a number of instrument parameters. We also present some first science results that give a taste of the range of science programs where SWIFT can have a substantial impact.

  4. TOGA COARE Satellite data summaries available on the World Wide Web

    NASA Technical Reports Server (NTRS)

    Chen, S. S.; Houze, R. A., Jr.; Mapes, B. E.; Brodzick, S. R.; Yutler, S. E.

    1995-01-01

    Satellite data summary images and analysis plots from the Tropical Ocean Global Atmosphere Coupled Ocean-Atmosphere Response Experiment (TOGA COARE), which were initially prepared in the field at the Honiara Operations Center, are now available on the Internet via World Wide Web browsers such as Mosaic. These satellite data summaries consist of products derived from the Japanese Geosynchronous Meteorological Satellite IR data: a time-size series of the distribution of contiguous cold cloudiness areas, weekly percent high cloudiness (PHC) maps, and a five-month time-longitudinal diagram illustrating the zonal motion of large areas of cold cloudiness. The weekly PHC maps are overlaid with weekly mean 850-hPa wind calculated from the European Centre for Medium-Range Weather Forecasts (ECMWF) global analysis field and can be viewed as an animation loop. These satellite summaries provide an overview of spatial and temporal variabilities of the cloud population and a large-scale context for studies concerning specific processes of various components of TOGA COARE.

  5. Deregulated HOX genes in ameloblastomas are located in physical contiguity to keratin genes.

    PubMed

    Schiavo, Giulia; D'Antò, Vincenzo; Cantile, Monica; Procino, Alfredo; Di Giovanni, Stefano; Valletta, Rossella; Terracciano, Luigi; Baumhoer, Daniel; Jundt, Gernot; Cillo, Clemente

    2011-11-01

    The expression of the HOX gene network in mid-stage human tooth development mostly concerns the epithelial tooth germ compartment and involves the C and D HOX loci. To further dissect the HOX gene implication with tooth epithelium differentiation we compared the expression of the whole HOX network in human ameloblastomas, as paradigm of epithelial odontogenic tumors, with tooth germs. We identified two ameloblastoma molecular types with respectively low and high number of active HOX C genes. The highly expressing HOX C gene ameloblastomas were characterized by a strong keratinized phenotype. Locus C HOX genes are located on chromosome 12q13-15 in physical contiguity with one of the two keratin gene clusters included in the human genome. The most posterior HOX C gene, HOX C13, is capable to interact with hair keratin genes located on the other keratin gene cluster in physical contiguity with the HOX B locus on chromosome 17q21-22. Inside the HOX C locus, a 2.2 kb ncRNA (HOTAIR) able to repress transcription, in cis, along the entire HOX C locus and, in trans, at the posterior region of the HOX D locus has recently been identified. Interestingly both loci are deregulated in ameloblastomas. Our finding support an important role of the HOX network in characterizing the epithelial tooth compartment. Furthermore, the physical contiguity between locus C HOX and keratin genes in normal tooth epithelium and their deregulation in the neoplastic counterparts suggest they may act on the same mechanism potentially involved with epithelial tumorigenesis. Copyright © 2011 Wiley Periodicals, Inc.

  6. Predicting onset and duration of airborne allergenic pollen season in the United States

    NASA Astrophysics Data System (ADS)

    Zhang, Yong; Bielory, Leonard; Cai, Ting; Mi, Zhongyuan; Georgopoulos, Panos

    2015-02-01

    Allergenic pollen is one of the main triggers of Allergic Airway Disease (AAD) affecting 5%-30% of the population in industrialized countries. A modeling framework has been developed using correlation and collinearity analyses, simulated annealing, and stepwise regression based on nationwide observations of airborne pollen counts and climatic factors to predict the onsets and durations of allergenic pollen seasons of representative trees, weeds and grass in the contiguous United States. Main factors considered are monthly, seasonal and annual mean temperatures and accumulative precipitations, latitude, elevation, Growing Degree Day (GDD), Frost Free Day (FFD), Start Date (SD) and Season Length (SL) in the previous year. The estimated mean SD and SL for birch (Betula), oak (Quercus), ragweed (Ambrosia), mugwort (Artemisia) and grass (Poaceae) pollen season in 1994-2010 are mostly within 0-6 days of the corresponding observations for the majority of the National Allergy Bureau (NAB) monitoring stations across the contiguous US. The simulated spatially resolved maps for onset and duration of allergenic pollen season in the contiguous US are consistent with the long term observations.

  7. Temporally inter-comparable maps of terrestrial wilderness and the Last of the Wild

    NASA Astrophysics Data System (ADS)

    Allan, James R.; Venter, Oscar; Watson, James E. M.

    2017-12-01

    Wilderness areas, defined as areas free of industrial scale activities and other human pressures which result in significant biophysical disturbance, are important for biodiversity conservation and sustaining the key ecological processes underpinning planetary life-support systems. Despite their importance, wilderness areas are being rapidly eroded in extent and fragmented. Here we present the most up-to-date temporally inter-comparable maps of global terrestrial wilderness areas, which are essential for monitoring changes in their extent, and for proactively planning conservation interventions to ensure their preservation. Using maps of human pressure on the natural environment for 1993 and 2009, we identified wilderness as all 'pressure free' lands with a contiguous area >10,000 km2. These places are likely operating in a natural state and represent the most intact habitats globally. We then created a regionally representative map of wilderness following the well-established 'Last of the Wild' methodology; which identifies the 10% area with the lowest human pressure within each of Earth's 60 biogeographic realms, and identifies the ten largest contiguous areas, along with all contiguous areas >10,000 km2.

  8. Time and Associative Learning.

    PubMed

    Balsam, Peter D; Drew, Michael R; Gallistel, C R

    2010-01-01

    In a basic associative learning paradigm, learning is said to have occurred when the conditioned stimulus evokes an anticipatory response. This learning is widely believed to depend on the contiguous presentation of conditioned and unconditioned stimulus. However, what it means to be contiguous has not been rigorously defined. Here we examine the empirical bases for these beliefs and suggest an alternative view based on the hypothesis that learning about the temporal relationships between events determines the speed of emergence, vigor and form of conditioned behavior. This temporal learning occurs very rapidly and prior to the appearance of the anticipatory response. The temporal relations are learned even when no anticipatory response is evoked. The speed with which an anticipatory response emerges is proportional to the informativeness of the predictive cue (CS) regarding the rate of occurrence of the predicted event (US). This analysis gives an account of what we mean by "temporal pairing" and is in accord with the data on speed of acquisition and basic findings in the cue competition literature. In this account, learning depends on perceiving and encoding temporal regularities rather than stimulus contiguities.

  9. Time and Associative Learning

    PubMed Central

    Balsam, Peter D; Drew, Michael R.; Gallistel, C.R.

    2010-01-01

    In a basic associative learning paradigm, learning is said to have occurred when the conditioned stimulus evokes an anticipatory response. This learning is widely believed to depend on the contiguous presentation of conditioned and unconditioned stimulus. However, what it means to be contiguous has not been rigorously defined. Here we examine the empirical bases for these beliefs and suggest an alternative view based on the hypothesis that learning about the temporal relationships between events determines the speed of emergence, vigor and form of conditioned behavior. This temporal learning occurs very rapidly and prior to the appearance of the anticipatory response. The temporal relations are learned even when no anticipatory response is evoked. The speed with which an anticipatory response emerges is proportional to the informativeness of the predictive cue (CS) regarding the rate of occurrence of the predicted event (US). This analysis gives an account of what we mean by “temporal pairing” and is in accord with the data on speed of acquisition and basic findings in the cue competition literature. In this account, learning depends on perceiving and encoding temporal regularities rather than stimulus contiguities. PMID:21359131

  10. The Simulium nigritarse subgroup (Diptera: Simuliidae) in Uganda: New species and country records.

    PubMed

    Krüger, Andreas

    2016-06-07

    Amongst blackfly samples from western Uganda three different morphospecies of the Simulium (Nevermannia) nigritarse Coquillett subgroup were identified. Of these, S. perforatum Fain & Dujardin showed the widest distribution and is reported from Uganda for the first time. In addition, two new species are described: S. bwambanum sp. nov. and S. itwariense sp. nov. Diagnostic characters are the different structures of the pupal cocoon, the configurations of the gill filaments and adult colour features.

  11. Ribbon Growth of Single Crystal GaAs for Solar Cell Application.

    DTIC Science & Technology

    1981-11-01

    Entered) 20. Abstract (Cont.) 7growth techniques, dendrite seeds, and melt chemistry were optimized during the course of the program; however...Faceted Web. 10 Crystal Grown From a Melt Doped With 1.0 Atomic% Ge. 17 The Ge-Doped Crystals Grew at Low Undercooling and Contained Flatter Textured-Web...Ge Melt Doping. The 18 Textured-Web Sections Were the Widest Achieved at Small Undercooling, ɝ.0°C. 12 Radiation Exchange Between the Melt Surface

  12. Community Care and Inclusion for People with an Intellectual Disability Jackson Robin & Lyons Maria (Eds) Community Care and Inclusion for People with an Intellectual Disability 256pp £25.00 Floris Books 9781782503330 1782503331 [Formula: see text].

    PubMed

    2017-06-21

    This book includes reflective and philosophical accounts that explore the widest context of community care. It is a collection of personal views and experiences from several authors. Many examples focus on the provision of the Camphill Village model across the world, and these provide a philosophical continuity throughout the book.

  13. Publishing the works of Nicholas Culpeper, astrological herbalist and translator of Latin medical works in seventeenth-century London.

    PubMed

    McCarl, M R

    1996-01-01

    This investigation attempts primarily to untangle the complex publishing history of the works of Nicholas Culpeper (1616-54), astrological herbalist and translator of Latin medical works. It therefore identifies those works published in seventeenth-century London: the study indicates that London stationers capitalized on the reputation of Nicholas Culpeper to build the widest possible market for his original astrological/herbal medical works and his translations from continental authors.

  14. Investigation the effect of lattice angle on the band gap width in 3D phononic crystals with rhombohedral(I) lattice

    NASA Astrophysics Data System (ADS)

    Salehi, H.; Aryadoust, M.; Shoushtari, M. Zargar

    2014-07-01

    In this paper, the propagation of acoustic waves in the phononic crystal of 3D with rhombohedral(I) lattice is studied theoretically. The crystal composite constituted of nickel spheres embedded in epoxy. The calculations of the band structure and density of states are performed with the plane wave expansion method in the irreducible part of Brillouin zone. In the present work, we have investigated the effect of lattice angle on the band structure and width of the band gap rhombohedral(I) lattice in the irreducible part of the first Brillouin zone and its planes separately. The results show that more than one complete band gape are formed in the four planes of the irreducible part. The most complete band gaps are formed in the (111) plane and the widest complete band gap in (443) with an angle greater than 80. So, if the sound passes through the (111) and (443) planes for the lattice angle close to 90, the crystal phononic displays the excellent insulation behavior. Moreover, in the other planes, the lattice angle does not affect on the width and the number of band gaps. Also, for the filling fraction 5 %, the widest complete band gap is formed. These results are consistent with the effect of symmetry on the band gap width, because the (111) plane has the most symmetry.

  15. The applications of satellites to communications, navigation and surveillance for aircraft operating over the contiguous United States

    NASA Technical Reports Server (NTRS)

    Craigie, J. H.; Otten, D. D.; Garabedian, A.; Morrison, D. D.; MALLINCKRODT; ZIPPER

    1970-01-01

    The objective was to determine on a priority basis the satellite applications to communications, navigation, and surveillance requirements for aircraft operating beyond 1975 over the contiguous United States and adjacent oceanic transition regions, and to determine if and how satellite technology can meet these requirements in a reliable, efficient, and economical manner. Major results and conclusions are as follows: (1) The satellite applications of greatest importance are surveillance and rapid collision warning communications; and (2) The necessary technology is available as demonstrated by an attractive system concept.

  16. Harnessing Big Data to Represent 30-meter Spatial Heterogeneity in Earth System Models

    NASA Astrophysics Data System (ADS)

    Chaney, N.; Shevliakova, E.; Malyshev, S.; Van Huijgevoort, M.; Milly, C.; Sulman, B. N.

    2016-12-01

    Terrestrial land surface processes play a critical role in the Earth system; they have a profound impact on the global climate, food and energy production, freshwater resources, and biodiversity. One of the most fascinating yet challenging aspects of characterizing terrestrial ecosystems is their field-scale (˜30 m) spatial heterogeneity. It has been observed repeatedly that the water, energy, and biogeochemical cycles at multiple temporal and spatial scales have deep ties to an ecosystem's spatial structure. Current Earth system models largely disregard this important relationship leading to an inadequate representation of ecosystem dynamics. In this presentation, we will show how existing global environmental datasets can be harnessed to explicitly represent field-scale spatial heterogeneity in Earth system models. For each macroscale grid cell, these environmental data are clustered according to their field-scale soil and topographic attributes to define unique sub-grid tiles. The state-of-the-art Geophysical Fluid Dynamics Laboratory (GFDL) land model is then used to simulate these tiles and their spatial interactions via the exchange of water, energy, and nutrients along explicit topographic gradients. Using historical simulations over the contiguous United States, we will show how a robust representation of field-scale spatial heterogeneity impacts modeled ecosystem dynamics including the water, energy, and biogeochemical cycles as well as vegetation composition and distribution.

  17. EarthScope's USArray: A Decade of Observations and Results

    NASA Astrophysics Data System (ADS)

    Woodward, R.; Busby, R. W.; Hafner, K.; Gridley, J. M.; Schultz, A.; Frassetto, A.; Simpson, D. W.

    2013-12-01

    EarthScope's USArray observatory provides unprecedented observations of geophysical targets across the contiguous United States through the systematic deployment of seismic, magnetotelluric, and atmospheric instruments. In addition, USArray includes tightly integrated data management and outreach activities. The seismic and atmospheric components of USArray consist of a Transportable Array (TA), Flexible Array (FA), and Reference Network. The TA has now occupied approximately 1700 sites spanning the entire contiguous 48 states, at 70 km inter-station spacing. These stations have provided broadband seismic, barometric pressure and atmospheric infrasound observations. The pool of instruments that comprise the FA have been deployed by numerous individual investigators in dense arrays to investigate local and regional features over time periods ranging from days to years. The Reference Network provides a permanent, stationary foundation for the TA and FA, with approximately 100 broadband stations deployed across the contiguous US at roughly 300 km spacing. The magnetotelluric (MT) component of USArray has provided both fixed and campaign-style long-period magnetotelluric observations at hundreds of locations across the US. Many of the field activities of USArray engaged both students and the public in important ways and this has been a significant component of USArray outreach. The TA alone has engaged well over one hundred students in site reconnaissance activities and placed seismic stations on the property of roughly a thousand different landowners. All data collected by USArray are openly available, most in real time. Many of the observations have also been incorporated into a variety of data products that have been developed to facilitate use of USArray by many different audiences. The scientific community has used USArray data to achieve a wide range of results--some that were anticipated when the facility was proposed and some that were completely unanticipated. Data products such as direct visualizations of seismic wave propagation observed by the TA have been viewed hundreds of thousands of times on the web by the general public. We will provide a brief overview of the deployments and accomplishments of USArray from the past ten years, and an overview of the significant and diverse scientific results that have been achieved. We will touch on some of the technologies and organizational and operational strategies that have enabled the success of USArray. We will conclude with a brief discussion of USArray plans for the next five years.

  18. The Large-scale Coronal Structure of the 2017 August 21 Great American Eclipse: An Assessment of Solar Surface Flux Transport Model Enabled Predictions and Observations

    NASA Astrophysics Data System (ADS)

    Nandy, Dibyendu; Bhowmik, Prantika; Yeates, Anthony R.; Panda, Suman; Tarafder, Rajashik; Dash, Soumyaranjan

    2018-01-01

    On 2017 August 21, a total solar eclipse swept across the contiguous United States, providing excellent opportunities for diagnostics of the Sun’s corona. The Sun’s coronal structure is notoriously difficult to observe except during solar eclipses; thus, theoretical models must be relied upon for inferring the underlying magnetic structure of the Sun’s outer atmosphere. These models are necessary for understanding the role of magnetic fields in the heating of the corona to a million degrees and the generation of severe space weather. Here we present a methodology for predicting the structure of the coronal field based on model forward runs of a solar surface flux transport model, whose predicted surface field is utilized to extrapolate future coronal magnetic field structures. This prescription was applied to the 2017 August 21 solar eclipse. A post-eclipse analysis shows good agreement between model simulated and observed coronal structures and their locations on the limb. We demonstrate that slow changes in the Sun’s surface magnetic field distribution driven by long-term flux emergence and its evolution governs large-scale coronal structures with a (plausibly cycle-phase dependent) dynamical memory timescale on the order of a few solar rotations, opening up the possibility for large-scale, global corona predictions at least a month in advance.

  19. Coupled B-snake grids and constrained thin-plate splines for analysis of 2-D tissue deformations from tagged MRI.

    PubMed

    Amini, A A; Chen, Y; Curwen, R W; Mani, V; Sun, J

    1998-06-01

    Magnetic resonance imaging (MRI) is unique in its ability to noninvasively and selectively alter tissue magnetization and create tagged patterns within a deforming body such as the heart muscle. The resulting patterns define a time-varying curvilinear coordinate system on the tissue, which we track with coupled B-snake grids. B-spline bases provide local control of shape, compact representation, and parametric continuity. Efficient spline warps are proposed which warp an area in the plane such that two embedded snake grids obtained from two tagged frames are brought into registration, interpolating a dense displacement vector field. The reconstructed vector field adheres to the known displacement information at the intersections, forces corresponding snakes to be warped into one another, and for all other points in the plane, where no information is available, a C1 continuous vector field is interpolated. The implementation proposed in this paper improves on our previous variational-based implementation and generalizes warp methods to include biologically relevant contiguous open curves, in addition to standard landmark points. The methods are validated with a cardiac motion simulator, in addition to in-vivo tagging data sets.

  20. A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

    ClinicalTrials.gov

    2015-02-10

    Accelerated Phase Chronic Myelogenous Leukemia; Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Previously Treated Myelodysplastic Syndromes; Prolymphocytic Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Excess Blasts in Transformation; Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma

  1. MRI features of extramedullary myeloma.

    PubMed

    Tirumani, Sree Harsha; Shinagare, Atul B; Jagannathan, Jyothi P; Krajewski, Katherine M; Munshi, Nikhil C; Ramaiya, Nikhil H

    2014-04-01

    The purpose of this study was to describe the MRI features of extramedullary myeloma and to evaluate the role of MRI in extramedullary myeloma. The cases of 28 patients (15 men, 13 women; mean age, 57.53 years; range, 34-83 years) with extramedullary myeloma who underwent MRI at one institution from January 2004 through December 2012 were retrospectively identified through an electronic search of an institutional radiology database. Two radiologists reviewed images from 44 MRI examinations in consensus to document the morphologic, signal-intensity, and enhancement characteristics of extramedullary myeloma. Electronic medical records were reviewed to document the indication for MRI and subsequent management of extramedullary myeloma. A total of 72 sites of extramedullary myeloma were noted, most commonly the paraspinal-epidural location (28/72, 39%). Two radiologic patterns were identified: lesions contiguous with bone (n = 44) and lesions noncontiguous with bone (n = 28). Lesions contiguous with bone were larger (p = 0.001; Student t test). Of 28 paraspinal-epidural lesions, 13 compressed the cord. Compared with skeletal muscle, most of the lesions were hypointense to isointense on T1-weighted images (67/72, 93.1%) and isointense to hyperintense on T2-weighted images (62/72, 86.1%). Lesions noncontiguous with bone were more often hypointense on T2-weighted images (8/28 vs 2/44; p = 0.006; Fisher exact test). Neurologic symptoms prompted MRI in most cases (n = 32/44). MRI was helpful in management by radiotherapy and surgery (19/28). Extramedullary myeloma can be contiguous or noncontiguous with bone. Lesions contiguous with bone are larger, often occur in a paraspinal or epidural location, and can cause cord compression. Lesions noncontiguous with bone can be T2 hypointense. MRI helps in treatment planning.

  2. Two-Phase Contiguous Supported Lipid Bilayer Model for Membrane Rafts via Polymer Blotting and Stenciling.

    PubMed

    Richards, Mark J; Daniel, Susan

    2017-02-07

    The supported lipid bilayer has been portrayed as a useful model of the cell membrane compatible with many biophysical tools and techniques that demonstrate its appeal in learning about the basic features of the plasma membrane. However, some of its potential has yet to be realized, particularly in the area of bilayer patterning and phase/composition heterogeneity. In this work, we generate contiguous bilayer patterns as a model system that captures the general features of membrane domains and lipid rafts. Micropatterned polymer templates of two types are investigated for generating patterned bilayer formation: polymer blotting and polymer lift-off stenciling. While these approaches have been used previously to create bilayer arrays by corralling bilayers patches with various types of boundaries impenetrable to bilayer diffusion, unique to the methods presented here, there are no physical barriers to diffusion. In this work, interfaces between contiguous lipid phases define the pattern shapes, with continuity between them allowing transfer of membrane-bound biomolecules between the phases. We examine effectors of membrane domain stability including temperature and cholesterol content to investigate domain dynamics. Contiguous patterning of supported bilayers as a model of lipid rafts expands the application of the SLB to an area with current appeal and brings with it a useful toolset for characterization and analysis. These combined tools should be helpful to researchers investigating lipid raft dynamics and function and biomolecule partitioning studies. Additionally, this patterning technique may be useful for applications such as bioseparations that exploit differences in lipid phase partitioning or creation of membranes that bind species like viruses preferentially at lipid phase boundaries, to name a few.

  3. Contiguous gene deletion of chromosome 2p16.3-p21 as a cause of Lynch syndrome.

    PubMed

    Salo-Mullen, Erin E; Lynn, Patricio B; Wang, Lu; Walsh, Michael; Gopalan, Anuradha; Shia, Jinru; Tran, Christina; Man, Fung Ying; McBride, Sean; Schattner, Mark; Zhang, Liying; Weiser, Martin R; Stadler, Zsofia K

    2018-01-01

    Lynch syndrome is an autosomal dominant condition caused by pathogenic mutations in the DNA mismatch repair (MMR) genes. Although commonly associated with clinical features such as intellectual disability and congenital anomalies, contiguous gene deletions may also result in cancer predisposition syndromes. We report on a 52-year-old male with Lynch syndrome caused by deletion of chromosome 2p16.3-p21. The patient had intellectual disability and presented with a prostatic adenocarcinoma with an incidentally identified synchronous sigmoid adenocarcinoma that exhibited deficient MMR with an absence of MSH2 and MSH6 protein expression. Family history was unrevealing. Physical exam revealed short stature, brachycephaly with a narrow forehead and short philtrum, brachydactyly of the hands, palmar transverse crease, broad and small feet with hyperpigmentation of the soles. The patient underwent total colectomy with ileorectal anastomosis for a pT3N1 sigmoid adenocarcinoma. Germline genetic testing of the MSH2, MSH6, and EPCAM genes revealed full gene deletions. SNP-array based DNA copy number analysis identified a deletion of 4.8 Mb at 2p16.3-p21. In addition to the three Lynch syndrome associated genes, the deleted chromosomal section encompassed genes including NRXN1, CRIPT, CALM2, FBXO11, LHCGR, MCFD2, TTC7A, EPAS1, PRKCE, and 15 others. Contiguous gene deletions have been described in other inherited cancer predisposition syndromes, such as Familial Adenomatous Polyposis. Our report and review of the literature suggests that contiguous gene deletion within the 2p16-p21 chromosomal region is a rare cause of Lynch syndrome, but presents with distinct phenotypic features, highlighting the need for recognition and awareness of this syndromic entity.

  4. Use of a Zero-Profile Device for Contiguous 2-Level Anterior Cervical Diskectomy and Fusion: Comparison with Cage with Plate Construct.

    PubMed

    Yun, Dong-Ju; Lee, Sang-Jin; Park, Sang-Joon; Oh, Hyeong Seok; Lee, Young Jae; Oh, Hyun Min; Lee, Sang-Ho

    2017-01-01

    A new zero-profile, standalone device (Zero P) was recently developed and has shown a lower incidence rate of complications and competitive clinical outcomes compared with anterior cervical cage with plate construct (CP) in single and multilevel anterior cervical diskectomy and fusion (ACDF). However, there is still concern whether Zero P is appropriate for multilevel ACDF. In addition, there have been few reports of contiguous 2-level ACDF used in conjunction with Zero P. We reviewed contiguous 2-level ACDF performed from December 2006 to February 2015. A total of 63 patients met inclusion criteria for the study (CP group = 32 cases; Zero P group = 31 cases). All preoperative and postoperative clinical and radiologic parameters were recorded. These parameters were compared between both groups. The postoperative change of Cobb S over time in the Zero P group was significantly different from that in the CP group. The maintenance of Cobb S in the Zero P group was better than that in the CP group (P < 0.05). The maintenance of anterior intervertebral disk height (IDH) at postoperative assessment for the Zero P group was significantly better than that in the CP group (P < 0.05). Within-group comparison of the postoperative change of anterior and posterior IDH over time revealed that the anterior IDH was significantly lower than the posterior IDH in the Zero P group (P < 0.05). For 2-level contiguous ACDF, the use of a zero-profile device has the capacity to show compatible outcomes in correction and maintenance of segmental angle if the anterior titanium alloy plate is properly positioned at the anterior vertebral line. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. A SUBSTELLAR COMMON PROPER-MOTION COMPANION TO THE PLEIAD H II 1348

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geissler, Kerstin; Metchev, Stanimir A.; Pham, Alfonse

    2012-02-10

    We announce the identification of a proper-motion companion to the star H II 1348, a K5 V member of the Pleiades open cluster. The existence of a faint point source 1.''1 away from H II 1348 was previously known from adaptive optics imaging by Bouvier et al. However, because of a high likelihood of background star contamination and in the absence of follow-up astrometry, Bouvier et al. tentatively concluded that the candidate companion was not physically associated with H II 1348. We establish the proper-motion association of the pair from adaptive optics imaging with the Palomar 5 m telescope. Adaptivemore » optics spectroscopy with the integral field spectrograph OSIRIS on the Keck 10 m telescope reveals that the companion has a spectral type of M8 {+-} 1. According to substellar evolution models, the M8 spectral type resides within the substellar mass regime at the age of the Pleiades. The primary itself is a known double-lined spectroscopic binary, which makes the resolved companion, H II 1348B, the least massive and widest component of this hierarchical triple system and the first substellar companion to a stellar primary in the Pleiades.« less

  6. A 3π Search for Planet Nine at 3.4 μm with WISE and NEOWISE

    NASA Astrophysics Data System (ADS)

    Meisner, A. M.; Bromley, B. C.; Kenyon, S. J.; Anderson, T. E.

    2018-04-01

    The recent “Planet Nine” hypothesis has led to many observational and archival searches for this giant planet proposed to orbit the Sun at hundreds of astronomical units. While trans-Neptunian object searches are typically conducted in the optical, models suggest Planet Nine could be self-luminous and potentially bright enough at ∼3–5 μm to be detected by the Wide-field Infrared Survey Explorer (WISE). We have previously demonstrated a Planet Nine search methodology based on time-resolved WISE coadds, allowing us to detect moving objects much fainter than would be possible using single-frame extractions. In the present work, we extend our 3.4 μm (W1) search to cover more than three-quarters of the sky and incorporate four years of WISE observations spanning a seven-year time period. This represents the deepest and widest-area WISE search for Planet Nine to date. We characterize the spatial variation of our survey’s sensitivity and rule out the presence of Planet Nine in the parameter space searched at W1 < 16.7 in high Galactic latitude regions (90% completeness).

  7. Disease Prevention and Health Promotion

    PubMed Central

    Ali, Ather; Katz, David L.

    2015-01-01

    As a discipline, preventive medicine has traditionally been described to encompass primary, secondary, and tertiary prevention. The fields of preventive medicine and public health share the objectives of promoting general health, preventing disease, and applying epidemiologic techniques to these goals. This paper discusses a conceptual approach between the overlap and potential synergies of integrative medicine principles and practices with preventive medicine in the context of these levels of prevention, acknowledging the relative deficiency of research on the effectiveness of practice-based integrative care. One goal of integrative medicine is to make the widest array of appropriate options available to patients, ultimately blurring the boundaries between conventional and complementary medicine. Both disciplines should be subject to rigorous scientific inquiry so that interventions that are efficacious and effective are systematically distinguished from those that are not. Furthermore, principles of preventive medicine can be infused into prevalent practices in complementary and integrative medicine, promoting public health in the context of more-responsible practices. The case is made that an integrative preventive approach involves the responsible use of science with responsiveness to the needs of patients that persist when conclusive data are exhausted, providing a framework to make clinical decisions among integrative therapies. PMID:26477898

  8. Station-Keeping Requirements for Astronomical Imaging with Constellations of Free-Flying Collectors

    NASA Technical Reports Server (NTRS)

    Allen, Ronald J.

    2004-01-01

    The requirements on station-keeping for constellations of free-flying collectors coupled as (future) imaging arrays in space for astrophysics applications are discussed. The typical knowledge precision required in the plane of the array depends on the angular size of the targets of interest; it is generally at a level of tens of centimeters for typical stellar targets, becoming of order centimeters only for the widest attainable fields of view. In the "piston" direction, perpendicular to the array, the typical knowledge precision required depends on the bandwidth of the signal, and is at a level of tens of wavelengths for narrow approx. 1% signal bands, becoming of order one wavelength only for the broadest bandwidths expected to be useful. The significance of this result is that, at this level of precision, it may be possible to provide the necessary knowledge of array geometry without the use of signal photons, thereby allowing observations of faint targets. "Closure-phase" imaging is a technique which has been very successfully applied to surmount instabilities owing to equipment and to the atmosphere, and which appears to be directly applicable to space imaging arrays where station-keeping drifts play the same role as (slow) atmospheric and equipment instabilities.

  9. Cretaceous Footprints Found on Goddard Campus

    NASA Image and Video Library

    2017-12-08

    The entire find, containing at least three dinosaur footprints, is approximately seven feet long and three feet across at its widest point. Additionally, the footprint-rich layer is bonded to a separate layer of iron-rich sandstone that complicated the efforts to extract and preserve it. Before removing the rock layer, Godfrey made a silicon-rubber cast of the prints, then jacketed the entire find in multiple layers of plaster-soaked burlap (i.e. just like a cast) to add rigidity and to further ward against breakage during transport. Galvanized steel pipes wrapped into the jacket acted like splints to provide additional structural support. The combined weight of the footprint, field jacket material and surrounding soil that was removed was estimated to be approximately 3,000 pounds, so extra care was taken in moving it to avoid damaging the rather extraordinary find. Credit: NASA/GSFC/Michelle Handleman NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  10. Cretaceous Footprints Found on Goddard Campus

    NASA Image and Video Library

    2017-12-08

    The entire find, containing at least three dinosaur footprints, is approximately seven feet long and three feet across at its widest point. Additionally, the footprint-rich layer is bonded to a separate layer of iron-rich sandstone that complicated the efforts to extract and preserve it. Before removing the rock layer, Godfrey made a silicon-rubber cast of the prints, then jacketed the entire find in multiple layers of plaster-soaked burlap (i.e. just like a cast) to add rigidity and to further ward against breakage during transport. Galvanized steel pipes wrapped into the jacket acted like splints to provide additional structural support. The combined weight of the footprint, field jacket material and surrounding soil that was removed was estimated to be approximately 3,000 pounds, so extra care was taken in moving it to avoid damaging the rather extraordinary find. Credit: NASA/GSFC/Rebecca Roth NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  11. The Sagittarius Dwarf Galaxy Survey (SDGS) - I. Colour-magnitude diagrams, reddening and population gradients. First evidence of a very metal-poor population

    NASA Astrophysics Data System (ADS)

    Bellazzini, M.; Ferraro, F. R.; Buonanno, R.

    1999-04-01

    We present the first results of a large photometric survey devoted to the study of the star formation history of the Sagittarius dwarf spheroidal galaxy (Sgr dSph). Three wide strips (size ~ 9 x 35 arcmin ^2) located at ~ (l deg b deg) = (6.5;-16), (6;-14), (5;-12) have been observed. Each strip is roughly east-west oriented, nearly along the major axis of the galaxy. A control field (size ~ 9 x 24 arcmin ^2), located outside the body of Sgr dSph [~ (l deg b deg) = (354;-14)] has also been observed for statistical decontamination purposes. Accurate and well-calibrated V, I photometry down to V ~ 22 has been obtained for ~ 90 000 stars towards the Sgr dSph and ~ 8000 stars in the control field. This is the largest photometric sample (covering the widest spatial extension) ever observed in the Sgr dSph up to now. The main new results presented in this paper are: (1) the possible discovery of a strong asymmetry in the distribution of stars along the major axis, since the north-western arm of the Sgr galaxy (i.e. the region nearer to the Galactic bulge) apparently shows a significant deficiency of Sgr stars and (2) the first direct detection of a very metal-poor (and presumably old) population in the Sgr stellar content. Hints at a metallicity gradient towards the densest region of the galaxy are also reported.

  12. Engineering on-chip nanoporous gold material libraries via precision photothermal treatment [Precision Photothermal Annealing of Nanoporous Gold Thin Films for the Microfabrication of a Single-ship Material Libraries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chapman, Christopher A. R.; Wang, Ling; Biener, Juergen

    Single-chip material libraries of thin films of nanostructured materials are a promising approach for high throughput studies of structure-property relationship in the fields of physics and biology. Nanoporous gold (np-Au), produced by an alloy corrosion process, is a nanostructured material of specific interest in both these fields. One attractive property of np-Au is its self-similar coarsening behavior by thermally induced surface diffusion. However, traditional heat application techniques for the modification of np-Au are bulk processes that cannot be used to generate a library of different pore sizes on a single chip. Laser micromachining offers an attractive solution to this problemmore » by providing a means to apply energy with high spatial and temporal resolution. In our present study we use finite element multiphysics simulations to predict the effects of laser mode (continuous-wave vs. pulsed) and supporting substrate thermal conductivity on the local np-Au film temperatures during photothermal annealing and subsequently investigate the mechanisms by which the np-Au network is coarsening. Our simulations predict that continuous-wave mode laser irradiation on a silicon supporting substrate supports the widest range of morphologies that can be created through the photothermal annealing of thin film np-Au. Using this result we successfully fabricate a single-chip material library consisting of 81 np-Au samples of 9 different morphologies for use in increased throughput material interaction studies.« less

  13. Precision Photothermal Annealing of Nanoporous Gold Thin Films for the Microfabrication of a Single-chip Material Libraries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harris, C. D.; Shen, N.; Rubenchik, A.

    2015-06-30

    Single-chip material libraries of thin films of nanostructured materials are a promising approach for high throughput studies of structure-property relationship in the fields of physics and biology. Nanoporous gold (np-Au), produced by an alloy corrosion process, is a nanostructured material of specific interest in both these fields. One attractive property of np-Au is its self-similar coarsening behavior by thermally induced surface diffusion. However, traditional heat application techniques for the modification of np-Au are bulk processes that cannot be used to generate a library of different pore sizes on a single chip. Laser micromachining offers an attractive solution to this problemmore » by providing a means to apply energy with high spatial and temporal resolution. In the present study we use finite element multiphysics simulations to predict the effects of laser mode (continuous-wave vs. pulsed) and supporting substrate thermal conductivity on the local np-Au film temperatures during photothermal annealing and subsequently investigate the mechanisms by which the np-Au network is coarsening. Our simulations predict that continuous-wave mode laser irradiation on a silicon supporting substrate supports the widest range of morphologies that can be created through the photothermal annealing of thin film np-Au. Using this result we successfully fabricate a single-chip material library consisting of 81 np-Au samples of 9 different morphologies for use in increased throughput material interaction studies.« less

  14. Comparison of field portable measurements of ultrafine TiO2: X-ray fluorescence, laser-induced breakdown spectroscopy, and Fourier-transform infrared spectroscopy.

    PubMed

    LeBouf, Ryan F; Miller, Arthur L; Stipe, Christopher; Brown, Jonathan; Murphy, Nate; Stefaniak, Aleksandr B

    2013-06-01

    Laboratory measurements of ultrafine titanium dioxide (TiO2) particulate matter loaded on filters were made using three field portable methods (X-ray fluorescence (XRF), laser-induced breakdown spectroscopy (LIBS), and Fourier-transform infrared (FTIR) spectroscopy) to assess their potential for determining end-of-shift exposure. Ultrafine TiO2 particles were aerosolized and collected onto 37 mm polycarbonate track-etched (PCTE) filters in the range of 3 to 578 μg titanium (Ti). Limit of detection (LOD), limit of quantification (LOQ), and calibration fit were determined for each measurement method. The LOD's were 11.8, 0.032, and 108 μg Ti per filter, for XRF, LIBS, and FTIR, respectively and the LOQ's were 39.2, 0.11, and 361 μg Ti per filter, respectively. The XRF calibration curve was linear over the widest dynamic range, up to the maximum loading tested (578 μg Ti per filter). LIBS was more sensitive but, due to the sample preparation method, the highest loaded filter measurable was 252 μg Ti per filter. XRF and LIBS had good predictability measured by regressing the predicted mass to the gravimetric mass on the filter. XRF and LIBS produced overestimations of 4% and 2%, respectively, with coefficients of determination (R(2)) of 0.995 and 0.998. FTIR measurements were less dependable due to interference from the PCTE filter media and overestimated mass by 2% with an R(2) of 0.831.

  15. Engineering on-chip nanoporous gold material libraries via precision photothermal treatment [Precision Photothermal Annealing of Nanoporous Gold Thin Films for the Microfabrication of a Single-ship Material Libraries

    DOE PAGES

    Chapman, Christopher A. R.; Wang, Ling; Biener, Juergen; ...

    2016-01-01

    Single-chip material libraries of thin films of nanostructured materials are a promising approach for high throughput studies of structure-property relationship in the fields of physics and biology. Nanoporous gold (np-Au), produced by an alloy corrosion process, is a nanostructured material of specific interest in both these fields. One attractive property of np-Au is its self-similar coarsening behavior by thermally induced surface diffusion. However, traditional heat application techniques for the modification of np-Au are bulk processes that cannot be used to generate a library of different pore sizes on a single chip. Laser micromachining offers an attractive solution to this problemmore » by providing a means to apply energy with high spatial and temporal resolution. In our present study we use finite element multiphysics simulations to predict the effects of laser mode (continuous-wave vs. pulsed) and supporting substrate thermal conductivity on the local np-Au film temperatures during photothermal annealing and subsequently investigate the mechanisms by which the np-Au network is coarsening. Our simulations predict that continuous-wave mode laser irradiation on a silicon supporting substrate supports the widest range of morphologies that can be created through the photothermal annealing of thin film np-Au. Using this result we successfully fabricate a single-chip material library consisting of 81 np-Au samples of 9 different morphologies for use in increased throughput material interaction studies.« less

  16. A General Purpose Experiment Controller for low cost Space Application

    NASA Astrophysics Data System (ADS)

    Guzman-Garcia, D.; Rowland, D. E.; Uribe, P.; Nieves-Chinchilla, T.

    2012-12-01

    Space activities are very expensive and include a high degree of risk. Nowadays, CubeSat missions represent a fast and inexpensive way to conduct scientific space research. These platforms are less expensive to develop and build than conventional satellites. There are ample demonstration that these platforms are well suited for a wide range of science missions in different fields, such as astrobiology, astronomy, atmospheric science, space weather and biology. This paper presents a hybrid "processor in an Field Programmable Gate Array (FPGA)" experiment/spacecraft controller for Cubesat missions. The system has two objectives, first is to obtain a multipurpose and easily customizable system aimed at processing the data from the widest kind of instruments and second, to provide the system with the highest processing capabilities in order to be able to perform complex onboard algorithms. Due to the versatility of the system and its reduced dimensions, it can be employed in different space platforms. The system is envisioned to be employed for the first time as the smart radio receiver for the upcoming NASA FireStation instrument. It is one of four experiments manifested to fly on an experiment pallet the U.S Department of Defense plans to deploy on the International Space Station in 2013. FireStation will continue analyzing the link between the Lightning and the Terrestrial Gamma Rays initiated by the FireFly Cubesat. The system is responsible for the management of a set of small Heliophysics instrumentats, including a photometer, magnetometer, and electric and magnetic field antennas. A description of the system architecture and its main features are presented. The main functional and performance tests during the integration and calibration phase of the instruments are also discussed.

  17. Alternative Suspension System for Space Shuttle Avionics Shelf

    NASA Technical Reports Server (NTRS)

    Biele, Frank H., III

    2010-01-01

    Engineers working in the Aerospace field under deadlines and strict budgets often miss the opportunity to design something that is considered new or innovative, favoring instead to use the tried-and-true design over those that may, in fact, be more efficient. This thesis examines an electronic equipment stowage shelf suspended from a frame in the cargo bay (mid fuselage) of the United States Space Transportation System (STS), the Space Shuttle, and 3 alternative designs. Four different designs are examined and evaluated. The first design is a conventional truss, representing the tried and true approach. The second is a cable dome type structure consisting of struts and pre-stressed wiring. The third and fourth are double layer tensegrity systems consisting of contiguous struts of the order k=1 and k=2 respectively.

  18. Widely tunable Tm-doped mode-locked all-fiber laser

    PubMed Central

    Yan, Zhiyu; Sun, Biao; Li, Xiaohui; Luo, Jiaqi; Shum, Perry Ping; Yu, Xia; Zhang, Ying; Wang, Qi Jie

    2016-01-01

    We demonstrated a widely tunable Tm-doped mode-locked all-fiber laser, with the widest tunable range of 136 nm, from 1842 to 1978 nm. Nonlinear polarization evolution (NPE) technique is employed to enable mode-locking and the wavelength-tunable operation. The widely tunable range attributes to the NPE-induced transmission modulation and bidirectional pumping mechanism. Such kind of tunable mode-locked laser can find various applications in optical communications, spectroscopy, time-resolved measurement, and among others. PMID:27263655

  19. Political orientation and perceptions of adolescent autonomy and judicial culpability.

    PubMed

    Reppucci, N Dickon; Scott, Elizabeth; Antonishak, Jill

    2009-01-01

    This study probed general attitudes about processing youths in adult criminal court across a range of offenses, explored attitudes about age of autonomous decision-making for several activities outside the criminal justice context, and examined the interaction between these two realms. The major finding was that adults favor adult punishment of adolescent offenders at younger ages than they favor autonomy in other decision-making contexts; the gap is widest for those who identify themselves as conservatives. 2009 John Wiley & Sons, Ltd.

  20. Reaping healthy profits. 100 hospitals manage to come out on top even in year plagued by financial ills.

    PubMed

    Lovern, E

    2000-12-11

    The 100 Top Hospitals financially outperformed their peers this year by the widest margin ever, posting an 8.7% total profit margin. If hospitals nationwide performed at the level of the top facilities, hospital expenses would decline by $12 billion a year, deaths would go down by nearly 87,000 and complications would be cut by 57,000. Some 63 of this year's top performers have been on the list before. Knowing their secrets is valuable.

  1. Selected Static Anatomic Measures Predict Overuse Injuries in Female Military Recruits

    DTIC Science & Technology

    2008-04-22

    caliper with a Vernier scale were placed at the widest point (iliac tubercle) on the right and left sides of the subject’s pelvis . 15 The width of...the pelvis girdle was recorded to the nearest 0.1 em. Knee Alignment Subjects were asked to stand with knees locked and feet shoulder-width apart... pelvis a~ a right angle to the table. If the leg settled above horizontal (intermediate) it was recorded as a positive I (tight ITB) test. 16 Data

  2. Selected Static Anatomic Measures Predict Overuse Injuries in Female Military Recruits

    DTIC Science & Technology

    2010-05-01

    caliper with a Vernier scale were placed at the widest point (iliac tubercle) on the right and left sides of the subject’s pelvis . 15 The width of...the pelvis girdle was recorded to the nearest 0.1 em. Knee Alignment Subjects were asked to stand with knees locked and feet shoulder-width apart... pelvis a~ a right angle to the table. If the leg settled above horizontal (intermediate) it was recorded as a positive I (tight ITB) test. 16 Data

  3. Navy Chaplains as Religious Advisors: A Combatant Commander’s Strategic Asset in Conflict, Reconstruction and Peace

    DTIC Science & Technology

    2012-04-05

    attempting to foster a climate of fairness, trust, and accountability .40 As the essential advisor, the chaplain operates as the moral conscience for the...local community. In doing so, the chaplain affords the widest possible free exercise of religion in the most cost effective manner. In addition...Operations, JP 1-05 (Washington, DC: Joint Forces Staff, November 2009), i. 13 SACNAVINST 1730.10, 1. 14 Clifford Drury , The History of the

  4. Historical Astrolexicography and Old Publications

    NASA Astrophysics Data System (ADS)

    Mahoney, Terry J.

    I describe how the principles of lexicography have been applied in limited ways in astronomy and look at the revision work under way for the third edition of the Oxford English Dictionary, which, when completed, will contain the widest and most detailed coverage of the astronomical lexicon in the English language. Finally, I argue the need for a dedicated historical dictionary of astronomy based rigorously on a corpus of quotations from sources published in English from the beginnings of written English to the present day.

  5. Heat transfer device

    NASA Technical Reports Server (NTRS)

    Eaton, L. R. (Inventor)

    1976-01-01

    An improved heat transfer device particularly suited for use as an evaporator plate in a diffusion cloud chamber. The device is characterized by a pair of mutually spaced heat transfer plates, each being of a planar configuration, having a pair of opposed surfaces defining therebetween a heat pipe chamber. Within the heat pipe chamber, in contiguous relation with the pair of opposed surfaces, there is disposed a pair of heat pipe wicks supported in a mutually spaced relationship by a foraminous spacer of a planar configuration. A wick including a foraminous layer is contiguously related to the external surfaces of the heat transfer plates for uniformly wetting these surfaces.

  6. Contiguous metallic rings: an inductive mesh with high transmissivity, strong electromagnetic shielding, and uniformly distributed stray light.

    PubMed

    Tan, Jiubin; Lu, Zhengang

    2007-02-05

    This paper presents the experimental study on an inductive mesh composed of contiguous metallic rings fabricated using UV-lithography on quartz glass. Experimental results indicate that, at the same period and linewidth as square mesh, ring mesh has better transmissivity for its higher obscuration ratio, stronger electromagnetic shielding performance for its smaller maximum aperture, and less degradation of imaging quality for its lower ratio and uniform distribution of high order diffraction energy. It is therefore concluded that this kind of ring mesh can be used as high-pass filters to provide electromagnetic shielding of optical transparent elements.

  7. Wound tube heat exchanger

    DOEpatents

    Ecker, Amir L.

    1983-01-01

    What is disclosed is a wound tube heat exchanger in which a plurality of tubes having flattened areas are held contiguous adjacent flattened areas of tubes by a plurality of windings to give a double walled heat exchanger. The plurality of windings serve as a plurality of effective force vectors holding the conduits contiguous heat conducting walls of another conduit and result in highly efficient heat transfer. The resulting heat exchange bundle is economical and can be coiled into the desired shape. Also disclosed are specific embodiments such as the one in which the tubes are expanded against their windings after being coiled to insure highly efficient heat transfer.

  8. Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas

    ClinicalTrials.gov

    2018-06-07

    AIDS-Related Plasmablastic Lymphoma; AIDS-Related Primary Effusion Lymphoma; CD20 Positive; HIV Infection; Plasmablastic Lymphoma; Primary Effusion Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Stage I Diffuse Large B-Cell Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage II Diffuse Large B-Cell Lymphoma; Stage II Grade 3 Contiguous Follicular Lymphoma; Stage II Grade 3 Non-Contiguous Follicular Lymphoma; Stage III Diffuse Large B-Cell Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage IV Diffuse Large B-Cell Lymphoma; Stage IV Grade 3 Follicular Lymphoma

  9. Geochemical map of the Chama River Canyon Wilderness and contiguous roadless area, Rio Arriba County, New Mexico

    USGS Publications Warehouse

    Ridgley, Jennie L.

    1986-01-01

    The Chama River Canyon Wilderness, in Rio Arriba County, north-central New Mexico, covers 50,300 acres (20,364 hectares) within the Coyote and Cuba Ranger Districts of the Santa Fe National Forest and the Canjilon Ranger District of the Carson National Forest. In 1979 the U.S. Forest Service, under the Forest Service Roadless Area Review and Evaluation (RARE II) program, designated three additional areas, contiguous to the wilderness, for further planning to assess wilderness characteristics. These areas, totaling 4,800 acres (1,945 hectares), were collectively designated Roadless area 03098; they have since been dropped from consideration. 

  10. It’s The Information!

    PubMed Central

    Ward, Ryan D.; Gallistel, C.R.; Balsam, Peter D

    2013-01-01

    Learning in conditioning protocols has long been thought to depend on temporal contiguity between the conditioned stimulus and the unconditioned stimulus. This conceptualization has led to a preponderance of associative models of conditioning. We suggest that trial-based associative models that posit contiguity as the primary principle underlying learning are flawed, and provide a brief review of an alternative, information theoretic approach to conditioning. The information that a CS conveys about the timing of the next US can be derived from the temporal parameters of a conditioning protocol. According to this view, a CS will support conditioned responding if, and only if, it reduces uncertainty about the timing of the next US. PMID:23384660

  11. Temporally inter-comparable maps of terrestrial wilderness and the Last of the Wild

    PubMed Central

    Allan, James R.; Venter, Oscar; Watson, James E.M.

    2017-01-01

    Wilderness areas, defined as areas free of industrial scale activities and other human pressures which result in significant biophysical disturbance, are important for biodiversity conservation and sustaining the key ecological processes underpinning planetary life-support systems. Despite their importance, wilderness areas are being rapidly eroded in extent and fragmented. Here we present the most up-to-date temporally inter-comparable maps of global terrestrial wilderness areas, which are essential for monitoring changes in their extent, and for proactively planning conservation interventions to ensure their preservation. Using maps of human pressure on the natural environment for 1993 and 2009, we identified wilderness as all ‘pressure free’ lands with a contiguous area >10,000 km2. These places are likely operating in a natural state and represent the most intact habitats globally. We then created a regionally representative map of wilderness following the well-established ‘Last of the Wild’ methodology; which identifies the 10% area with the lowest human pressure within each of Earth’s 60 biogeographic realms, and identifies the ten largest contiguous areas, along with all contiguous areas >10,000 km2. PMID:29231923

  12. Hiding in Plain Sight: A Case for Cryptic Metapopulations in Brook Trout (Salvelinus fontinalis)

    PubMed Central

    Kazyak, David C.; Hilderbrand, Robert H.; King, Tim L.; Keller, Stephen R.; Chhatre, Vikram E.

    2016-01-01

    A fundamental issue in the management and conservation of biodiversity is how to define a population. Spatially contiguous fish occupying a stream network have often been considered to represent a single, homogenous population. However, they may also represent multiple discrete populations, a single population with genetic isolation-by-distance, or a metapopulation. We used microsatellite DNA and a large-scale mark-recapture study to assess population structure in a spatially contiguous sample of Brook Trout (Salvelinus fontinalis), a species of conservation concern. We found evidence for limited genetic exchange across small spatial scales and in the absence of barriers to physical movement. Mark-recapture and stationary passive integrated transponder antenna records demonstrated that fish from two tributaries very seldom moved into the opposite tributary, but movements between the tributaries and mainstem were more common. Using Bayesian genetic clustering, we identified two genetic groups that exhibited significantly different growth rates over three years of study, yet survival rates were very similar. Our study highlights the importance of considering the possibility of multiple genetically distinct populations occurring within spatially contiguous habitats, and suggests the existence of a cryptic metapopulation: a spatially continuous distribution of organisms exhibiting metapopulation-like behaviors. PMID:26730588

  13. Hiding in Plain Sight: A Case for Cryptic Metapopulations in Brook Trout (Salvelinus fontinalis).

    PubMed

    Kazyak, David C; Hilderbrand, Robert H; King, Tim L; Keller, Stephen R; Chhatre, Vikram E

    2016-01-01

    A fundamental issue in the management and conservation of biodiversity is how to define a population. Spatially contiguous fish occupying a stream network have often been considered to represent a single, homogenous population. However, they may also represent multiple discrete populations, a single population with genetic isolation-by-distance, or a metapopulation. We used microsatellite DNA and a large-scale mark-recapture study to assess population structure in a spatially contiguous sample of Brook Trout (Salvelinus fontinalis), a species of conservation concern. We found evidence for limited genetic exchange across small spatial scales and in the absence of barriers to physical movement. Mark-recapture and stationary passive integrated transponder antenna records demonstrated that fish from two tributaries very seldom moved into the opposite tributary, but movements between the tributaries and mainstem were more common. Using Bayesian genetic clustering, we identified two genetic groups that exhibited significantly different growth rates over three years of study, yet survival rates were very similar. Our study highlights the importance of considering the possibility of multiple genetically distinct populations occurring within spatially contiguous habitats, and suggests the existence of a cryptic metapopulation: a spatially continuous distribution of organisms exhibiting metapopulation-like behaviors.

  14. High-order multiband encoding in the heart.

    PubMed

    Cunningham, Charles H; Wright, Graham A; Wood, Michael L

    2002-10-01

    Spatial encoding with multiband selective excitation (e.g., Hadamard encoding) has been restricted to a small number of slices because the RF pulse becomes unacceptably long when more than about eight slices are encoded. In this work, techniques to shorten multiband RF pulses, and thus allow larger numbers of slices, are investigated. A method for applying the techniques while retaining the capability of adaptive slice thickness is outlined. A tradeoff between slice thickness and pulse duration is shown. Simulations and experiments with the shortened pulses confirmed that motion-induced excitation profile blurring and phase accrual were reduced. The connection between gradient hardware limitations, slice thickness, and flow sensitivity is shown. Excitation profiles for encoding 32 contiguous slices of 1-mm thickness were measured experimentally, and the artifact resulting from errors in timing of RF pulse relative to gradient was investigated. A multiband technique for imaging 32 contiguous 2-mm slices, with adaptive slice thickness, was developed and demonstrated for coronary artery imaging in healthy subjects. With the ability to image high numbers of contiguous slices, using relatively short (1-2 ms) RF pulses, multiband encoding has been advanced further toward practical application. Copyright 2002 Wiley-Liss, Inc.

  15. Method for prefetching non-contiguous data structures

    DOEpatents

    Blumrich, Matthias A [Ridgefield, CT; Chen, Dong [Croton On Hudson, NY; Coteus, Paul W [Yorktown Heights, NY; Gara, Alan G [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Heidelberger, Philip [Cortlandt Manor, NY; Hoenicke, Dirk [Ossining, NY; Ohmacht, Martin [Brewster, NY; Steinmacher-Burow, Burkhard D [Mount Kisco, NY; Takken, Todd E [Mount Kisco, NY; Vranas, Pavlos M [Bedford Hills, NY

    2009-05-05

    A low latency memory system access is provided in association with a weakly-ordered multiprocessor system. Each processor in the multiprocessor shares resources, and each shared resource has an associated lock within a locking device that provides support for synchronization between the multiple processors in the multiprocessor and the orderly sharing of the resources. A processor only has permission to access a resource when it owns the lock associated with that resource, and an attempt by a processor to own a lock requires only a single load operation, rather than a traditional atomic load followed by store, such that the processor only performs a read operation and the hardware locking device performs a subsequent write operation rather than the processor. A simple perfecting for non-contiguous data structures is also disclosed. A memory line is redefined so that in addition to the normal physical memory data, every line includes a pointer that is large enough to point to any other line in the memory, wherein the pointers to determine which memory line to prefect rather than some other predictive algorithm. This enables hardware to effectively prefect memory access patterns that are non-contiguous, but repetitive.

  16. Optimization and experimental validation of stiff porous phononic plates for widest complete bandgap of mixed fundamental guided wave modes

    NASA Astrophysics Data System (ADS)

    Hedayatrasa, Saeid; Kersemans, Mathias; Abhary, Kazem; Uddin, Mohammad; Van Paepegem, Wim

    2018-01-01

    Phononic crystal plates (PhPs) have promising application in manipulation of guided waves for design of low-loss acoustic devices and built-in acoustic metamaterial lenses in plate structures. The prominent feature of phononic crystals is the existence of frequency bandgaps over which the waves are stopped, or are resonated and guided within appropriate defects. Therefore, maximized bandgaps of PhPs are desirable to enhance their phononic controllability. Porous PhPs produced through perforation of a uniform background plate, in which the porous interfaces act as strong reflectors of wave energy, are relatively easy to produce. However, the research in optimization of porous PhPs and experimental validation of achieved topologies has been very limited and particularly focused on bandgaps of flexural (asymmetric) wave modes. In this paper, porous PhPs are optimized through an efficient multiobjective genetic algorithm for widest complete bandgap of mixed fundamental guided wave modes (symmetric and asymmetric) and maximized stiffness. The Pareto front of optimization is analyzed and variation of bandgap efficiency with respect to stiffness is presented for various optimized topologies. Selected optimized topologies from the stiff and compliant regimes of Pareto front are manufactured by water-jetting an aluminum plate and their promising bandgap efficiency is experimentally observed. An optimized Pareto topology is also chosen and manufactured by laser cutting a Plexiglas (PMMA) plate, and its performance in self-collimation and focusing of guided waves is verified as compared to calculated dispersion properties.

  17. Giddings Edwards (Cretaceous) field, south Texas: carbonate channel or elongate buildup

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lomando, A.J.; Mazzullo, S.J.

    1989-03-01

    Giddings Edwards field, located in Fayette County, Texas, is situated on the broad Cretaceous (Albian) shallow shelf, approximately 20 mi north of the main Edwards shelf-margin reef trend. The Giddings field produces gas from an elongate stratigraphic trap approximately 9.5 mi long and 1.8 mi wide, encased in argillaceous lime mudstones and shales; the field is oriented normal to the contiguous Edwards reef trend. Available cores and cuttings samples from the central portion of the field indicate that the field reservoir is composed of biopackstones and grainstones interpreted to have been deposited in a high-energy shelf environment. The facies systemmore » is characterized by stacked reservoirs having a maximum gross pay thickness of over 100 ft, containing primary interparticle and secondary biomoldic porosity, both of which have been modified slightly by chemical compaction and partial occlusion by sparry calcite and saddle dolomite cements. Despite reasonable subsurface sample and mechanical log control within and surrounding the field, its depositional origin remains equivocal. Such uncertainty has important bearing on predictive models for the exploration for additional Edwards shelfal hydrocarbon reservoirs. The elongate, biconvex geometry of the productive carbonate sands, their northward thinning, and apparent updip bifurcation suggest deposition in a shallow-shelf channel system. By contrast, an alternative correlation and interpretation based on geometry and facies is that of an elongate in-situ carbonate buildup. A number of modern analogs of elongate buildups normal to major reef systems are available from which to compare and model the depositional system of Giddings Edwards field. The evaluation of this field serves as an example of using a multiple working hypothesis to develop an accurate exploration model.« less

  18. Laboratory and Field Spectroscopy of Moon analogue material

    NASA Astrophysics Data System (ADS)

    Offringa, Marloes; Foing, Bernard H.

    2016-07-01

    Samples derived from terrestrial analogue sites are studied to gain insight into lunar processes in their geological context (Foing, Stoker, Ehrenfreund, 2011). For this study samples from the volcanic region of the Eifel, Germany collected during our latest field campaigns in November 2015 and February 2016 (Foing et al., 2010), are analyzed with a variety of spectrometers. The aim is to obtain a database of analyzed samples that could be used as a reference for future in situ measurements. We also use a documented set of Moon-Mars relevant minerals curated at VU Amsterdam. We are using systematically for all samples UV-VIS and NIR reflectance spectrometers, and sporadically a Fourier Transform Infrared (FTIR) spectrometer, an X-Ray Fluorescence (XRF) spectrometer and a Raman laser spectrometer on control samples. Calibration of the UV-VIS and NIR reflectance spectrometers is the main focus of this research in order to obtain the clearest spectra. The calibration of the UV-VIS and NIR reflectance spectrometers requires the use of a good light source as well as suitable optical fibers to create a signal that covers the widest range in wavelengths available. To eliminate noise towards the edges of this range, multiple measurements are averaged and data is processed by dividing the signal by reference spectra. Obtained spectra can be tested for accuracy by comparing them with stationary laboratory spectrometers such as the FTIR spectrometer. The Raman, UV-VIS and NIR are also used in combination with the ExoGeoLab mock-up lander during field campaigns (Foing, Stoker, Ehrenfreund, 2011) also brought again to Eifel in February 2016, to prove the applicability of the equipment in the field. Acknowledgements: we thank Dominic Doyle for ESTEC optical lab support, Euan Monaghan (Leiden U) for FTIR measurement support, Wim van Westrenen for access to VU samples, Oscar Kamps (Utrecht U./ESTEC), Aidan Cowley (EAC) and Matthias Sperl (DLR) for support discussions

  19. Splitting attention across the two visual fields in visual short-term memory.

    PubMed

    Delvenne, Jean-Francois; Holt, Jessica L

    2012-02-01

    Humans have the ability to attentionally select the most relevant visual information from their extrapersonal world and to retain it in a temporary buffer, known as visual short-term memory (VSTM). Research suggests that at least two non-contiguous items can be selected simultaneously when they are distributed across the two visual hemifields. In two experiments, we show that attention can also be split between the left and right sides of internal representations held in VSTM. Participants were asked to remember several colors, while cues presented during the delay instructed them to orient their attention to a subset of memorized colors. Experiment 1 revealed that orienting attention to one or two colors strengthened equally participants' memory for those colors, but only when they were from separate hemifields. Experiment 2 showed that in the absence of attentional cues the distribution of the items in the visual field per se had no effect on memory. These findings strongly suggest the existence of independent attentional resources in the two hemifields for selecting and/or consolidating information in VSTM. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. Antibody responses of mice exposed to low-power microwaves under combined, pulse-and-amplitude modulation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Veyret, B.; Bouthet, C.; Deschaux, P.

    Irradiation by pulsed microwaves (9.4 GHz, 1 microsecond pulses at 1,000/s), both with and without concurrent amplitude modulation (AM) by a sinusoid at discrete frequencies between 14 and 41 MHz, was assessed for effects on the immune system of Balb/C mice. The mice were immunized either by sheep red blood cells (SRBC) or by glutaric-anhydride conjugated bovine serum albumin (GA-BSA), then exposed to the microwaves at a low rms power density (30 microW/cm2; whole-body-averaged SAR approximately 0.015 W/kg). Sham exposure or microwave irradiation took place during each of five contiguous days, 10 h/day. The antibody response was evaluated by themore » plaque-forming cell assay (SRBC experiment) or by the titration of IgM and IgG antibodies (GA-BSA experiment). In the absence of AM, the pulsed field did not greatly alter immune responsiveness. In contrast, exposure to the field under the combined-modulation condition resulted in significant, AM-frequency-dependent augmentation or weakening of immune responses.« less

  1. Nance-Horan syndrome: a contiguous gene syndrome involving deletion of the amelogenin gene? A case report and molecular analysis.

    PubMed

    Franco, E; Hodgson, S; Lench, N; Roberts, G J

    1995-03-01

    A case of Nance-Horan syndrome in a male is presented, with some features of the condition in his carrier mother and her mother. It is proposed that Nance-Horan syndrome might be a contiguous gene syndrome mapping to chromosome Xp21.2-p22.3. The proband had congenital cataract microphthalmia and dental abnormalities including screwdriver shaped incisors and evidence of enamel pitting hypoplasia. The region Xp21.2-p22.3 also contains the tooth enamel protein gene, amelogenin (AMGX). Using molecular genetic techniques, we have shown that there is no evidence that the AMGX gene is deleted in this case of the Nance-Horan syndrome.

  2. A context-based theory of recency and contiguity in free recall

    PubMed Central

    Sederberg, Per B.; Howard, Marc W.; Kahana, Michael J.

    2008-01-01

    We present a new model of free recall based on Howard and Kahana’s (2002) temporal context model and Usher and McClelland’s (2001) leaky-accumulator decision model. In this model, contextual drift gives rise to both short-term and long-term recency effects, and contextual retrieval gives rise to short-term and long-term contiguity effects, Recall decisions are controlled by a race between competitive leaky-accumulators. The model captures the dynamics of immediate, delayed, and continual distractor free recall, demonstrating that dissociations between short- and long-term recency can naturally arise from a model that uses an internal contextual state as the sole cue for retrieval across time scales. PMID:18954208

  3. Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma

    ClinicalTrials.gov

    2018-01-24

    Acute Lymphoblastic Leukemia; Adult T Acute Lymphoblastic Leukemia; Ann Arbor Stage II Adult T-Cell Leukemia/Lymphoma; Ann Arbor Stage II Childhood Lymphoblastic Lymphoma; Ann Arbor Stage II Contiguous Adult Lymphoblastic Lymphoma; Ann Arbor Stage II Non-Contiguous Adult Lymphoblastic Lymphoma; Ann Arbor Stage III Adult Lymphoblastic Lymphoma; Ann Arbor Stage III Adult T-Cell Leukemia/Lymphoma; Ann Arbor Stage III Childhood Lymphoblastic Lymphoma; Ann Arbor Stage IV Adult Lymphoblastic Lymphoma; Ann Arbor Stage IV Adult T-Cell Leukemia/Lymphoma; Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma; Childhood T Acute Lymphoblastic Leukemia; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia

  4. It's the information!

    PubMed

    Ward, Ryan D; Gallistel, C R; Balsam, Peter D

    2013-05-01

    Learning in conditioning protocols has long been thought to depend on temporal contiguity between the conditioned stimulus and the unconditioned stimulus. This conceptualization has led to a preponderance of associative models of conditioning. We suggest that trial-based associative models that posit contiguity as the primary principle underlying learning are flawed, and provide a brief review of an alternative, information theoretic approach to conditioning. The information that a CS conveys about the timing of the next US can be derived from the temporal parameters of a conditioning protocol. According to this view, a CS will support conditioned responding if, and only if, it reduces uncertainty about the timing of the next US. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. Pore Pressure Pulse Drove the 2012 Emilia (Italy) Series of Earthquakes

    NASA Astrophysics Data System (ADS)

    Pezzo, Giuseppe; De Gori, Pasquale; Lucente, Francesco Pio; Chiarabba, Claudio

    2018-01-01

    The 2012 Emilia earthquakes sequence is the first debated case in Italy of destructive event possibly induced by anthropic activity. During this sequence, two main earthquakes occurred separated by 9 days on contiguous thrust faults. Scientific commissions engaged by the Italian government reported complementary scenarios on the potential trigger mechanism ascribable to exploitation of a nearby oil field. In this study, we combine a refined geodetic source model constrained by precise aftershock locations and an improved tomographic model of the area to define the geometrical relation between the activated faults and investigate possible triggering mechanisms. An aftershock decay rate that deviates from the classical Omori-like pattern and Vp/Vs changes along the fault system suggests that natural pore pressure pulse drove the space-time evolution of seismicity and the activation of the second main shock.

  6. Continuum analogues of contragredient Lie algebras (Lie algebras with a Cartan operator and nonlinear dynamical systems)

    NASA Astrophysics Data System (ADS)

    Saveliev, M. V.; Vershik, A. M.

    1989-12-01

    We present an axiomatic formulation of a new class of infinitedimensional Lie algebras-the generalizations of Z-graded Lie algebras with, generally speaking, an infinite-dimensional Cartan subalgebra and a contiguous set of roots. We call such algebras “continuum Lie algebras.” The simple Lie algebras of constant growth are encapsulated in our formulation. We pay particular attention to the case when the local algebra is parametrized by a commutative algebra while the Cartan operator (the generalization of the Cartan matrix) is a linear operator. Special examples of these algebras are the Kac-Moody algebras, algebras of Poisson brackets, algebras of vector fields on a manifold, current algebras, and algebras with differential or integro-differential cartan operator. The nonlinear dynamical systems associated with the continuum contragredient Lie algebras are also considered.

  7. BIG MAC: A bolometer array for mid-infrared astronomy, Center Director's Discretionary Fund

    NASA Technical Reports Server (NTRS)

    Telesco, C. M.; Decher, R.; Baugher, C.

    1985-01-01

    The infrared array referred to as Big Mac (for Marshall Array Camera), was designed for ground based astronomical observations in the wavelength range 5 to 35 microns. It contains 20 discrete gallium-doped germanium bolometer detectors at a temperature of 1.4K. Each bolometer is irradiated by a square field mirror constituting a single pixel of the array. The mirrors are arranged contiguously in four columns and five rows, thus defining the array configuration. Big Mac utilized cold reimaging optics and an up looking dewar. The total Big Mac system also contains a telescope interface tube for mounting the dewar and a computer for data acquisition and processing. Initial astronomical observations at a major infrared observatory indicate that Big Mac performance is excellent, having achieved the design specifications and making this instrument an outstanding tool for astrophysics.

  8. Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer

    ClinicalTrials.gov

    2017-12-05

    Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Blastic Phase Chronic Myelogenous Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; Testicular Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia; Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies; Waldenström Macroglobulinemia

  9. Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

    ClinicalTrials.gov

    2017-04-17

    Accelerated Phase Chronic Myelogenous Leukemia; Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Aggressive NK-cell Leukemia; AIDS-related Diffuse Large Cell Lymphoma; AIDS-related Diffuse Mixed Cell Lymphoma; AIDS-related Diffuse Small Cleaved Cell Lymphoma; AIDS-related Immunoblastic Large Cell Lymphoma; AIDS-related Lymphoblastic Lymphoma; AIDS-related Peripheral/Systemic Lymphoma; AIDS-related Primary CNS Lymphoma; AIDS-related Small Noncleaved Cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Blastic Phase Chronic Myelogenous Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia; Childhood Diffuse Large Cell Lymphoma; Childhood Grade III Lymphomatoid Granulomatosis; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; HIV Infection; HIV-associated Hodgkin Lymphoma; Intraocular Lymphoma; Isolated Plasmacytoma of Bone; Juvenile Myelomonocytic Leukemia; Mast Cell Leukemia; Meningeal Chronic Myelogenous Leukemia; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Myeloid/NK-cell Acute Leukemia; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Central Nervous System Lymphoma; Primary Myelofibrosis; Primary Systemic Amyloidosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage 0 Chronic Lymphocytic Leukemia; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Hodgkin Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Hodgkin Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; T-cell Large Granular Lymphocyte Leukemia; Testicular Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific; Waldenström Macroglobulinemia

  10. Temporally contiguous pencast instruction promotes meaningful learning for dental and dental hygiene students in physiology.

    PubMed

    Roesch, Darren M

    2014-01-01

    Smartpens allow for the creation of computerized "pencasts" that combine voice narration with handwritten notes and illustrations. The purpose of this study was to test the effects of voluntary participation in extracurricular instruction with a pencast on student learning. Dental and dental hygiene students were given instruction in a complex physiological topic using lecture and static slides. An Internet link to a pencast that covered the complex topic in a more temporally contiguous fashion was also provided for voluntary review. The students were given a multiple-choice exam that consisted of retention and transfer test questions. Sixty-nine percent of the students who did not watch the pencast and 89 percent of the students who watched the pencast answered the retention test question correctly (p=0.08). Fifty-four percent of the students who did not watch the pencast and 90 percent of the students who watched the pencast answered the transfer test question correctly (p=0.005). This finding indicates that students who watched the pencast performed better on a transfer test, a measurement of meaningful learning, than students who received only the narrated instruction with static images. This supports the hypothesis that temporally contiguous instruction promotes more meaningful learning than lecture accompanied only by static slide images.

  11. MDC-Analyzer: a novel degenerate primer design tool for the construction of intelligent mutagenesis libraries with contiguous sites.

    PubMed

    Tang, Lixia; Wang, Xiong; Ru, Beibei; Sun, Hengfei; Huang, Jian; Gao, Hui

    2014-06-01

    Recent computational and bioinformatics advances have enabled the efficient creation of novel biocatalysts by reducing amino acid variability at hot spot regions. To further expand the utility of this strategy, we present here a tool called Multi-site Degenerate Codon Analyzer (MDC-Analyzer) for the automated design of intelligent mutagenesis libraries that can completely cover user-defined randomized sequences, especially when multiple contiguous and/or adjacent sites are targeted. By initially defining an objective function, the possible optimal degenerate PCR primer profiles could be automatically explored using the heuristic approach of Greedy Best-First-Search. Compared to the previously developed DC-Analyzer, MDC-Analyzer allows for the existence of a small amount of undesired sequences as a tradeoff between the number of degenerate primers and the encoded library size while still providing all the benefits of DC-Analyzer with the ability to randomize multiple contiguous sites. MDC-Analyzer was validated using a series of randomly generated mutation schemes and experimental case studies on the evolution of halohydrin dehalogenase, which proved that the MDC methodology is more efficient than other methods and is particularly well-suited to exploring the sequence space of proteins using data-driven protein engineering strategies.

  12. Poverty and corruption compromise tropical forest reserves.

    PubMed

    Wright, S Joseph; Sanchez-Azofeifa, G Arturo; Portillo-Quintero, Carlos; Davies, Diane

    2007-07-01

    We used the global fire detection record provided by the satellite-based Moderate Resolution Imaging Spectroradiometer (MODIS) to determine the number of fires detected inside 823 tropical and subtropical moist forest reserves and for contiguous buffer areas 5, 10, and 15 km wide. The ratio of fire detection densities (detections per square kilometer) inside reserves to their contiguous buffer areas provided an index of reserve effectiveness. Fire detection density was significantly lower inside reserves than in paired, contiguous buffer areas but varied by five orders of magnitude among reserves. The buffer: reserve detection ratio varied by up to four orders of magnitude among reserves within a single country, and median values varied by three orders of magnitude among countries. Reserves tended to be least effective at reducing fire frequency in many poorer countries and in countries beset by corruption. Countries with the most successful reserves include Costa Rica, Jamaica, Malaysia, and Taiwan and the Indonesian island of Java. Countries with the most problematic reserves include Cambodia, Guatemala, Paraguay, and Sierra Leone and the Indonesian portion of Borneo. We provide fire detection density for 3964 tropical and subtropical reserves and their buffer areas in the hope that these data will expedite further analyses that might lead to improved management of tropical reserves.

  13. Modelling space of spread Dengue Hemorrhagic Fever (DHF) in Central Java use spatial durbin model

    NASA Astrophysics Data System (ADS)

    Ispriyanti, Dwi; Prahutama, Alan; Taryono, Arkadina PN

    2018-05-01

    Dengue Hemorrhagic Fever is one of the major public health problems in Indonesia. From year to year, DHF causes Extraordinary Event in most parts of Indonesia, especially Central Java. Central Java consists of 35 districts or cities where each region is close to each other. Spatial regression is an analysis that suspects the influence of independent variables on the dependent variables with the influences of the region inside. In spatial regression modeling, there are spatial autoregressive model (SAR), spatial error model (SEM) and spatial autoregressive moving average (SARMA). Spatial Durbin model is the development of SAR where the dependent and independent variable have spatial influence. In this research dependent variable used is number of DHF sufferers. The independent variables observed are population density, number of hospitals, residents and health centers, and mean years of schooling. From the multiple regression model test, the variables that significantly affect the spread of DHF disease are the population and mean years of schooling. By using queen contiguity and rook contiguity, the best model produced is the SDM model with queen contiguity because it has the smallest AIC value of 494,12. Factors that generally affect the spread of DHF in Central Java Province are the number of population and the average length of school.

  14. Concepts, The Journal of Defense Systems Acquisition Management. Spring 1982, Volume 5, Number 2. Two Perspectives on Multiyear Procurement European Overview Part II Competition: Does It Lower Costs?

    DTIC Science & Technology

    1982-01-01

    that gained widest acceptance was Abraham Maslow’s hierarchy of human needs.2 His theory was based on two simple premises: People have many needs, and...an Industrial Civilization, 2nd Edition, Boston, Harvard University, 1946. 2. Abraham Maslow , Motivation and Personality, New York, Harper & Bros...management theories to use as a basis for developing their own management approach. The author discusses some of the management theories that have been

  15. Transporting Clinical Research to Community Settings: Designing and Conducting a Multisite Trial of Brief Strategic Family Therapy

    PubMed Central

    Robbins, Michael S.; Alonso, Elizabeth; Horigian, Viviana E.; Bachrach, Ken; Burlew, Kathy; Carrión, Ibis S.; Hodgkins, Candace C.; Miller, Michael; Schindler, Eric; VanDeMark, Nancy; Henderson, Craig; Szapocznik, José

    2010-01-01

    This paper describes the development and implementation of a trial of Brief Strategic Family Therapy (BSFT), an evidence-based drug intervention for adolescents, in eight community substance abuse treatment programs. Researchers and treatment programs collaborated closely to identify and overcome challenges, many of them related to achieving results that were both scientifically rigorous and applicable to the widest possible variety of adolescent substance abuse treatment programs. To meet these challenges, the collaborative team drew on lessons and practices from efficacy, effectiveness, and implementation research. PMID:22002455

  16. MODIS: Moderate-resolution imaging spectrometer. Earth observing system, volume 2B

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The Moderate-Resolution Imaging Spectrometer (MODIS), as presently conceived, is a system of two imaging spectroradiometer components designed for the widest possible applicability to research tasks that require long-term (5 to 10 years), low-resolution (52 channels between 0.4 and 12.0 micrometers) data sets. The system described is preliminary and subject to scientific and technological review and modification, and it is anticipated that both will occur prior to selection of a final system configuration; however, the basic concept outlined is likely to remain unchanged.

  17. Actively mode-locked Tm-Ho:LiYF4 and Tm-Ho:BaY2F8 lasers

    NASA Astrophysics Data System (ADS)

    Gatti, D.; Galzerano, G.; Toncelli, A.; Tonelli, M.; Laporta, P.

    2007-01-01

    We report on the generation of mode-locking pulse trains with high average output powers from diode-pumped Tm-Ho:LiYF4 and Tm-Ho:BaY2F8 lasers emitting at around 2 μm. The highest output power of 365 mW was obtained with the Tm-Ho:YLF4 laser, whereas the shortest pulse duration of 120 ps and the widest tunability range of 59 nm was achieved with the Tm-Ho:BaY2F8 laser.

  18. Assessing the Added Value of Dynamical Downscaling Using ...

    EPA Pesticide Factsheets

    In this study, the Standardized Precipitation Index (SPI) is used to ascertain the added value of dynamical downscaling over the contiguous United States. WRF is used as a regional climate model (RCM) to dynamically downscale reanalysis fields to compare values of SPI over drought timescales that have implications for agriculture and water resources planning. The regional climate generated by WRF has the largest improvement over reanalysis for SPI correlation with observations as the drought timescale increases. This suggests that dynamically downscaled fields may be more reliable than larger-scale fields for water resource applications (e.g., water storage within reservoirs). WRF improves the timing and intensity of moderate to extreme wet and dry periods, even in regions with homogenous terrain. This study also examines changes in SPI from the extreme drought of 1988 and three “drought busting” tropical storms. Each of those events illustrates the importance of using downscaling to resolve the spatial extent of droughts. The analysis of the “drought busting” tropical storms demonstrates that while the impact of these storms on ending prolonged droughts is improved by the RCM relative to the reanalysis, it remains underestimated. These results illustrate the importance and some limitations of using RCMs to project drought. The National Exposure Research Laboratory’s Atmospheric Modeling Division (AMAD) conducts research in support of EPA’s mission t

  19. 76 FR 72020 - Virginia Disaster #VA-00039

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-21

    ... the disaster: Primary Counties: Fairfax, Prince William. Contiguous Counties: Virginia: Alexandria... City, Stafford. District of Columbia. Maryland: Charles, Montgomery, Prince George's. The Interest...

  20. Effect of scale on trait predictors of species responses to agriculture.

    PubMed

    Gilroy, James J; Medina Uribe, Claudia A; Haugaasen, Torbjørn; Edwards, David P

    2015-04-01

    Species persistence in human-altered landscapes can depend on factors operating at multiple spatial scales. To understand anthropogenic impacts on biodiversity, it is useful to examine relationships between species traits and their responses to land-use change. A key knowledge gap concerns whether these relationships vary depending on the scale of response under consideration. We examined how local- and large-scale habitat variables influence the occupancy dynamics of a bird community in cloud forest zones in the Colombian Chocó-Andes. Using data collected across a continuum of forest and agriculture, we examined which traits best predict species responses to local variation in farmland and which traits best predict species responses to isolation from contiguous forest. Global range size was a strong predictor of species responses to agriculture at both scales; widespread species were less likely to decline as local habitat cover decreased and as distance from forest increased. Habitat specialization was a strong predictor of species responses only at the local scale. Open-habitat species were particularly likely to increase as pasture increased, but they were relatively insensitive to variation in distance to forest. Foraging plasticity and flocking behavior were strong predictors of species responses to distance from forest, but not their responses to local habitat. Species with lower plasticity in foraging behaviors and obligate flock-following species were more likely to decline as distance from contiguous forest increased. For species exhibiting these latter traits, persistence in tropical landscapes may depend on the protection of larger contiguous blocks of forest, rather than the integration of smaller-scale woodland areas within farmland. Species listed as threatened or near threatened on the International Union for Conservation of Nature Red List were also more likely to decline in response to both local habitat quality and isolation from forest relative to least-concern species, underlining the importance of contiguous forests for threatened taxa. © 2014 Society for Conservation Biology.

  1. TRMM-3B43 Bias Correction over the High Elevations of the Contiguous United States

    NASA Astrophysics Data System (ADS)

    Hashemi, H.; Nordin, K. M.; Lakshmi, V.; Knight, R. J.

    2016-12-01

    Precipitation can be quantified using a rain gauge network, or a remotely sensed precipitation product. Ultimately, the choice of dataset depends on the particular application, the catchment size, climate and the time period of study. In a region with a long record and a dense rain gauge network, the elevation-modified ground-based precipitation product, PRISM, has been found to work well. However, in poorly gauged regions the use of remotely sensed precipitation products is an absolute necessity. The Tropical Rainfall Measuring Mission (TRMM) has provided valuable precipitation datasets for hydrometeorological studies over the past two decades (1998-2015). One concern regarding the usage of TRMM data is the accuracy of the precipitation estimates, when compared to those obtained using PRISM. The reason for this concern is that TRMM and PRISM do not always agree and, typically, TRMM underestimates PRISM over the mountainous regions of the United States. In this study, we develop a correction function to improve the accuracy of the TRMM monthly product (TRMM-3B43) by estimating and removing the bias in the satellite data using the ground-based precipitation product, PRISM. We observe a strong relationship between the bias and land surface elevation; TRMM-3B43 tends to underestimate the PRISM product at altitudes greater than 1500 m above mean sea level (m.amsl) in the contiguous United States. A relationship is developed between TRMM-PRISM bias and elevation. The correction function is used to adjust the TRMM monthly precipitation using PRISM and elevation data. The model is calibrated using 25% of the available time period and the remaining 75% of the time period is used for validation. The corrected TRMM-3B43 product is verified for the high elevations over the contiguous United States and two local regions in the mountainous areas of the western United States. The results show a significant improvement in the accuracy of the TRMM product in the high elevations of the contiguous United States.

  2. Human Episodic Memory Retrieval Is Accompanied by a Neural Contiguity Effect.

    PubMed

    Folkerts, Sarah; Rutishauser, Ueli; Howard, Marc W

    2018-04-25

    Cognitive psychologists have long hypothesized that experiences are encoded in a temporal context that changes gradually over time. When an episodic memory is retrieved, the state of context is recovered-a jump back in time. We recorded from single units in the medial temporal lobe of epilepsy patients performing an item recognition task. The population vector changed gradually over minutes during presentation of the list. When a probe from the list was remembered with high confidence, the population vector reinstated the temporal context of the original presentation of that probe during study, a neural contiguity effect that provides a possible mechanism for behavioral contiguity effects. This pattern was only observed for well remembered probes; old probes that were not well remembered showed an anti-contiguity effect. These results constitute the first direct evidence that recovery of an episodic memory in humans is associated with retrieval of a gradually changing state of temporal context, a neural "jump back in time" that parallels the act of remembering. SIGNIFICANCE STATEMENT Episodic memory is the ability to relive a specific experience from one's life. For decades, researchers have hypothesized that, unlike other forms of memory that can be described as simple associations between stimuli, episodic memory depends on the recovery of a neural representation of spatiotemporal context. During study of a sequence of stimuli, the brain state of epilepsy patients changed slowly over at least a minute. When the participant remembered a particular event from the list, this gradually changing state was recovered. This provides direct confirmation of the prediction from computational models of episodic memory. The resolution of this point means that the study of episodic memory can focus on the mechanisms by which this representation of spatiotemporal context is maintained and sometimes recovered. Copyright © 2018 the authors 0270-6474/18/384200-12$15.00/0.

  3. Radiofrequency multielectrode catheter ablation in the atrium.

    PubMed

    Panescu, D; Fleischman, S D; Whayne, J G; Swanson, D K; Mirotznik, M S; McRury, I; Haines, D E

    1999-04-01

    We developed a temperature-controlled radiofrequency (RF) system which can ablate by delivering energy to up to six 12.5 mm long coil electrodes simultaneously. Temperature feedback was obtained from temperature sensors placed at each end of coil electrodes, in diametrically opposite positions. The coil electrodes were connected in parallel, via a set of electronic switches, to a 150 W 500 kHz temperature-controlled RF generator. Temperatures measured at all user-selected coil electrodes were processed by a microcontroller which sent the maximum value to the temperature input of the generator. The generator adjusted the delivered power to regulate the temperature at its input within a 5 degrees C interval about a user-defined set point. The microcontroller also activated the corresponding electronic switches so that temperatures at all selected electrodes were controlled within a 5 degrees C interval with respect to each other. Physical aspects of tissue heating were first analysed using finite element models and current density measurements. Results from these analyses also constituted design input. The performance of this system was studied in vitro and in vivo. In vitro, at set temperatures of 70 degrees C, 85% of the lesions were contiguous. All lesions created at set temperatures of 80 and 90 degrees C were contiguous. The lesion length increased almost linearly with the number of electrodes. Power requirements to reach a set temperature were larger as more electrodes were driven by the generator. The system impedance decreased as more electrodes were connected in the ablation circuit and reached a low of 45.5 ohms with five coil electrodes in the circuit. In vivo, right atrial lesions were created in eight mongrel canines. The power needed to reach 70 degrees C set temperature varied between 15 and 114 W. The system impedance was 105+/-16 ohms, with one coil electrode in the circuit, and dropped to 75+/-12 ohms when two coil electrodes were simultaneously powered. The length and the width of the lesion set varied between 17.6+/-6.1 and 59.2+/-11.7 mm and 5.9+/-0.7 and 7.1+/-1.2 mm respectively. No sudden impedance rises occurred and 75% of the lesions were contiguous. From the set of contiguous lesions, 90% were potentially therapeutic as they were transmural and extended over the entire target region. The average total procedure and fluoroscopy times were 83.4 and 5.9 min respectively. We concluded that the system can safely perform long and contiguous lesions in canine right atria.

  4. SPINOFF 2000

    NASA Technical Reports Server (NTRS)

    2000-01-01

    For the past 42 years, NASA has made special efforts to ensure the widest possible dissemination of its research and technology developments. We share the wealth of technology developed for our missions with the nation's industries to contribute to US economic strength and quality of life. For the past 27 years, this publication has provided you with over 1,200 examples of products and services developed as a direct result of commercial partnerships between NASA and the business community. Examples have covered products from fire retardant materials and air pollution monitors to non-invasive cardiac monitors and sensors for environmental control. In the Technology Transfer and Outreach section of Spinoff 2000, we highlight the activities of our Ames Research Center's Commercial Technology Office (CTO). Their efforts to facilitate and support technology commercialization are representative of the CTO at each field center. Increased activities to accelerate the dissemination of technologies, speed up the process of patent licensing, quicken the release of software for beta testing, support and manage incubators, and hasten the collaboration with commercial and academic organizations will continue to maximize the earliest potential commercial utilization of NASA's new inventions and technologies. Spinoff 2000 is organized into three sections: (1) Aerospace and Development highlights major research and development efforts currently carried out at the 10 NASA field centers; (2) Commercial Benefits-Spinoffs describes commercially available products and services resulting from the transfer of NASA technology; and (3) Technology Transfer and Outreach features this year's center spotlight, NASA's Ames Research Center, and its commercialization efforts, as well as the mechanisms in place nationwide to assist US industry in obtaining, transferring, and applying NASA technology, expertise, and assistance.

  5. Classical Observations of Visual Binary and Multiple Stars

    NASA Astrophysics Data System (ADS)

    Mason, Brian D.

    2007-08-01

    The database of visual double star data has experienced tremendous changes, doubling in size during the last 25 years and growing at an ever increasing rate. Interferometric techniques have allowed the database to extend to much closer separation (and shorter periods), while longer timebases and higher-precision wide-field surveys have increased our knowledge of common proper motion pairs at the widest separations. These changes in the database are highlighted, describing the evolution of methods of observation (both historically and the past few years) and the effectiveness of these various methods in different regimes of separation/ period space. The various niches for wide- and narrow-field work as applied to double and multiple stars are examined and the different types of information which each can provide are also highlighted. After more than 20 years of successful work, speckle interferometry and conventional CCD astrometry have replaced filar micrometry and photography as the preferred classical techniques. Indeed, most work in filar micrometry is now being done by amateurs, although much of that community is also switching to CCDs and other electronic techniques. Despite the significant growth of the double star database, much still remains to be done, such as finding lost pairs, filling in missing parameters so that observing programs may be more efficient at observing stars appropriate to their capabilities, and providing at least approximate kinematic descriptions. Work on pairs described as neglected at the time of the last major WDS data release (2001) is given as a specific example of recent improvements, and finally the continued need to publish data using classical double star parameters is discussed.

  6. A Search for Optically Faint GEO Debris

    NASA Technical Reports Server (NTRS)

    Seitzer, Patrick; Lederer, Susan M.; Barker, Edwin S.; Cowardin, Heather; Abercromby, Kira J.; ilha, Jiri

    2011-01-01

    Existing optical surveys for debris at geosynchronous orbit (GEO) have been conducted with meter class telescopes, which have detection limits in the range of 18th-19th magnitude. We report on a new search for optically faint debris at GEO using the 6.5-m Magellan 1 telescope Walter Baade at Las Campanas Observatory in Chile. Our goal is to go as faint as possible and characterize the brightness distribution of debris fainter than R = 20th magnitude, corresponding to a size smaller than 10 cm assuming an albedo of 0.175. We wish to compare the inferred size distribution for GEO debris with that for LEO debris. We describe results obtained during 9.4 hours of observing time during 25-27 March 2011. We used the IMACS f/2 instrument, which has a mosaic of 8 CCDs, and a field of view of 30 arc-minutes in diameter. This is the widest field of view of any instrument on either Magellan telescope. All observations were obtained through a Sloan r filter. The limiting magnitude for 5 second exposures is estimated to be fainter than 22. With this small field of view and the limited observing time, our objective was to search for optically faint objects from the Titan 3C Transtage (1968-081) fragmentation in 1992. Eight debris pieces and the parent rocket body are in the Space Surveillance Network public catalog. We successfully tracked two cataloged pieces of Titan debris (SSN # 25001 and 33519) with the 6.5-m telescope, followed by a survey for objects on similar orbits but with a spread in mean anomaly. To detect bright objects over a wider field of view (1.6x1.6 degrees), we observed the same field centers at the same time through a similar filter with the 0.6-m MODEST (Michigan Orbital DEbris Survey Telescope), located 100 km to the south of Magellan at Cerro Tololo Inter-American Observatory, Chile. We will describe our experiences using Magellan, a telescope never used previously for orbital debris research, and our initial results.

  7. The Hubble Space Telescope Frontier Fields Program

    NASA Astrophysics Data System (ADS)

    Koekemoer, Anton M.; Mack, Jennifer; Lotz, Jennifer M.; Borncamp, David; Khandrika, Harish G.; Lucas, Ray A.; Martlin, Catherine; Porterfield, Blair; Sunnquist, Ben; Anderson, Jay; Avila, Roberto J.; Barker, Elizabeth A.; Grogin, Norman A.; Gunning, Heather C.; Hilbert, Bryan; Ogaz, Sara; Robberto, Massimo; Sembach, Kenneth; Flanagan, Kathryn; Mountain, Matt

    2017-08-01

    The Hubble Space Telescope Frontier Fields program is a large Director's Discretionary program of 840 orbits, to obtain ultra-deep observations of six strong lensing clusters of galaxies, together with parallel deep blank fields, making use of the strong lensing amplification by these clusters of distant background galaxies to detect the faintest galaxies currently observable in the high-redshift universe. The entire program has now completed successfully for all 6 clusters, namely Abell 2744, Abell S1063, Abell 370, MACS J0416.1-2403, MACS J0717.5+3745 and MACS J1149.5+2223,. Each of these was observed over two epochs, to a total depth of 140 orbits on the main cluster and an associated parallel field, obtaining images in ACS (F435W, F606W, F814W) and WFC3/IR (F105W, F125W, F140W, F160W) on both the main cluster and the parallel field in all cases. Full sets of high-level science products have been generated for all these clusters by the team at STScI, including cumulative-depth data releases during each epoch, as well as full-depth releases after the completion of each epoch. These products include all the full-depth distortion-corrected drizzled mosaics and associated products for each cluster, which are science-ready to facilitate the construction of lensing models as well as enabling a wide range of other science projects. Many improvements beyond default calibration for ACS and WFC3/IR are implemented in these data products, including corrections for persistence, time-variable sky, and low-level dark current residuals, as well as improvements in astrometric alignment to achieve milliarcsecond-level accuracy. The full set of resulting high-level science products and mosaics are publicly delivered to the community via the Mikulski Archive for Space Telescopes (MAST) to enable the widest scientific use of these data, as well as ensuring a public legacy dataset of the highest possible quality that is of lasting value to the entire community.

  8. The HST Frontier Fields: Complete High-Level Science Data Products for All 6 Clusters

    NASA Astrophysics Data System (ADS)

    Koekemoer, Anton M.; Mack, Jennifer; Lotz, Jennifer M.; Borncamp, David; Khandrika, Harish G.; Lucas, Ray A.; Martlin, Catherine; Porterfield, Blair; Sunnquist, Ben; Anderson, Jay; Avila, Roberto J.; Barker, Elizabeth A.; Grogin, Norman A.; Gunning, Heather C.; Hilbert, Bryan; Ogaz, Sara; Robberto, Massimo; Sembach, Kenneth; Flanagan, Kathryn; Mountain, Matt; HST Frontier Fields Team

    2017-01-01

    The Hubble Space Telescope Frontier Fields program (PI: J. Lotz) is a large Director's Discretionary program of 840 orbits, to obtain ultra-deep observations of six strong lensing clusters of galaxies, together with parallel deep blank fields, making use of the strong lensing amplification by these clusters of distant background galaxies to detect the faintest galaxies currently observable in the high-redshift universe. The entire program has now completed successfully for all 6 clusters, namely Abell 2744, Abell S1063, Abell 370, MACS J0416.1-2403, MACS J0717.5+3745 and MACS J1149.5+2223,. Each of these was observed over two epochs, to a total depth of 140 orbits on the main cluster and an associated parallel field, obtaining images in ACS (F435W, F606W, F814W) and WFC3/IR (F105W, F125W, F140W, F160W) on both the main cluster and the parallel field in all cases. Full sets of high-level science products have been generated for all these clusters by the team at STScI, including cumulative-depth data releases during each epoch, as well as full-depth releases after the completion of each epoch. These products include all the full-depth distortion-corrected drizzled mosaics and associated products for each cluster, which are science-ready to facilitate the construction of lensing models as well as enabling a wide range of other science projects. Many improvements beyond default calibration for ACS and WFC3/IR are implemented in these data products, including corrections for persistence, time-variable sky, and low-level dark current residuals, as well as improvements in astrometric alignment to achieve milliarcsecond-level accuracy. The full set of resulting high-level science products and mosaics are publicly delivered to the community via the Mikulski Archive for Space Telescopes (MAST) to enable the widest scientific use of these data, as well as ensuring a public legacy dataset of the highest possible quality that is of lasting value to the entire community.

  9. The HST Frontier Fields: Complete Observations and High-Level Science Data Products for All 6 Clusters

    NASA Astrophysics Data System (ADS)

    Koekemoer, Anton M.; Mack, Jennifer; Lotz, Jennifer M.; Borncamp, David; Khandrika, Harish G.; Lucas, Ray A.; Martlin, Catherine; Martlin, Catherine; Porterfield, Blair; Sunnquist, Ben; Anderson, Jay; Avila, Roberto J.; Barker, Elizabeth A.; Grogin, Norman A.; Gunning, Heather C.; Hilbert, Bryan; Ogaz, Sara; Robberto, Massimo; Sembach, Kenneth; Flanagan, Kathryn; Mountain, Matt; HST Frontier Fields Team

    2017-06-01

    The Hubble Space Telescope Frontier Fields program is a large Director's Discretionary program of 840 orbits, to obtain ultra-deep observations of six strong lensing clusters of galaxies, together with parallel deep blank fields, making use of the strong lensing amplification by these clusters of distant background galaxies to detect the faintest galaxies currently observable in the high-redshift universe. The entire program has now completed successfully for all 6 clusters, namely Abell 2744, Abell S1063, Abell 370, MACS J0416.1-2403, MACS J0717.5+3745 and MACS J1149.5+2223,. Each of these was observed over two epochs, to a total depth of 140 orbits on the main cluster and an associated parallel field, obtaining images in ACS (F435W, F606W, F814W) and WFC3/IR (F105W, F125W, F140W, F160W) on both the main cluster and the parallel field in all cases. Full sets of high-level science products have been generated for all these clusters by the team at STScI, including cumulative-depth data releases during each epoch, as well as full-depth releases after the completion of each epoch. These products include all the full-depth distortion-corrected drizzled mosaics and associated products for each cluster, which are science-ready to facilitate the construction of lensing models as well as enabling a wide range of other science projects. Many improvements beyond default calibration for ACS and WFC3/IR are implemented in these data products, including corrections for persistence, time-variable sky, and low-level dark current residuals, as well as improvements in astrometric alignment to achieve milliarcsecond-level accuracy. The full set of resulting high-level science products and mosaics are publicly delivered to the community via the Mikulski Archive for Space Telescopes (MAST) to enable the widest scientific use of these data, as well as ensuring a public legacy dataset of the highest possible quality that is of lasting value to the entire community.

  10. Gas-tungsten arc welding of aluminum alloys

    DOEpatents

    Frye, Lowell D.

    1984-01-01

    A gas-tungsten arc welding method for joining together structures formed of aluminum alloy with these structures disposed contiguously to a heat-damagable substrate of a metal dissimilar to the aluminum alloy. The method of the present invention is practiced by diamond machining the fay surfaces of the aluminum alloy structures to provide a mirror finish thereon having a surface roughness in the order of about one microinch. The fay surfaces are aligned and heated sufficiently by the tungsten electrode to fuse the aluminum alloy contiguous to the fay surfaces to effect the weld joint. The heat input used to provide an oxide-free weld is significantly less than that required if the fay surfaces were prepared by using conventional chemical and mechanical practices.

  11. Optimization of laminated stacking sequence for buckling load maximization by genetic algorithm

    NASA Technical Reports Server (NTRS)

    Le Riche, Rodolphe; Haftka, Raphael T.

    1992-01-01

    The use of a genetic algorithm to optimize the stacking sequence of a composite laminate for buckling load maximization is studied. Various genetic parameters including the population size, the probability of mutation, and the probability of crossover are optimized by numerical experiments. A new genetic operator - permutation - is proposed and shown to be effective in reducing the cost of the genetic search. Results are obtained for a graphite-epoxy plate, first when only the buckling load is considered, and then when constraints on ply contiguity and strain failure are added. The influence on the genetic search of the penalty parameter enforcing the contiguity constraint is studied. The advantage of the genetic algorithm in producing several near-optimal designs is discussed.

  12. Epithelioid Hemangioma Involving Three Contiguous Bones: a Case Report with a Review of the Literature

    PubMed Central

    Jinawath, Arthit; Jaovisidha, Suphaneewan

    2010-01-01

    An epithelioid hemangioma involving three contiguous bones in continuity has, to the best of our knowledge, not been reported in the literature. A case of a 48-year-old man presented with radiating pain to the lower thoracic region for two years. A radiograph and CT scan revealed both permeative osteolytic and multiple trabeculated lesions involving the left posterior part of the 10th rib as well as the 9th and 10th vertebral bodies in continuity and was misled as a malignant or infectious lesion. The histopathology and immuno-histochemistry of the lesion confirmed the diagnosis of an epithelioid hemangioma. The lesion was still stable as of three years after surgery. PMID:21076597

  13. Non-contiguous multifocal vertebral osteomyelitis caused by Serratia marcescens.

    PubMed

    Lau, Jen Xin; Li, Jordan Yuanzhi; Yong, Tuck Yean

    2015-03-01

    Serratia marcescens is a common nosocomial infection but a rare cause of osteomyelitis and more so of vertebral osteomyelitis. Vertebral osteomyelitis caused by this organism has been reported in few studies. We report a case of S. marcescens vertebral discitis and osteomyelitis affecting multiple non-contiguous vertebras. Although Staphylococcus aureus is the most common cause of vertebral osteomyelitis, rare causes, such as S. marcescens, need to be considered, especially when risk factors such as intravenous heroin use, post-spinal surgery and immunosuppression are present. Therefore, blood culture and where necessary biopsy of the infected region should be undertaken to establish the causative organism and determine appropriate antibiotic susceptibility. Prompt diagnosis of S. marcescens vertebral osteomyelitis followed by the appropriate treatment can achieve successful outcomes.

  14. Planned versus actual outcomes as a result of animal feeding operation decisions for managing phosphorus.

    PubMed

    Cabot, Perry E; Nowak, Pete

    2005-01-01

    The paper explores how decisions made on animal feeding operations (AFOs) influence the management of manure and phosphorus. Variability among these decisions from operation to operation and from field to field can influence the validity of nutrient loss risk assessments. These assessments are based on assumptions that the decision outcomes regarding manure distribution will occur as they are planned. The discrepancy between planned versus actual outcomes in phosphorus management was explored on nine AFOs managing a contiguous set of 210 fields in south-central Wisconsin. A total of 2611 soil samples were collected and multiple interviews conducted to assign phosphorus index (PI) ratings to the fields. Spearman's rank correlation coefficients (r(S)) indicated that PI ratings were less sensitive to soil test phosphorus (STP) levels (r(S) = 0.378), universal soil loss equation (USLE) (r(S) = 0.261), ratings for chemical fertilizer application (r(S) = 0.185), and runoff class (r(S) = -0.089), and more sensitive to ratings for manure application (r(S) = 0.854). One-way ANOVA indicated that mean field STP levels were more homogenous than field PI ratings between AFOs. Kolmogorov-Smirnov (K-S) tests displayed several nonsignificant comparisons for cumulative distribution functions, S(x), of mean STP levels on AFO fields. On the other hand, the K-S tests of S(x) for PI ratings indicated that the majority of these S(x) functions were significantly different between AFOs at or greater than the 0.05 significance level. Interviews suggested multiple reasons for divergence between planned and actual outcomes in managing phosphorus, and that this divergence arises at the strategic, tactical, and operational levels of decision-making.

  15. Extreme value analysis of the time derivative of the horizontal magnetic field and computed electric field

    NASA Astrophysics Data System (ADS)

    Wintoft, Peter; Viljanen, Ari; Wik, Magnus

    2016-05-01

    High-frequency ( ≈ minutes) variability of ground magnetic fields is caused by ionospheric and magnetospheric processes driven by the changing solar wind. The varying magnetic fields induce electrical fields that cause currents to flow in man-made conductors like power grids and pipelines. Under extreme conditions the geomagnetically induced currents (GIC) may be harmful to the power grids. Increasing our understanding of the extreme events is thus important for solar-terrestrial science and space weather. In this work 1-min resolution of the time derivative of measured local magnetic fields (|dBh/dt|) and computed electrical fields (Eh), for locations in Europe, have been analysed with extreme value analysis (EVA). The EVA results in an estimate of the generalized extreme value probability distribution that is described by three parameters: location, width, and shape. The shape parameter controls the extreme behaviour. The stations cover geomagnetic latitudes from 40 to 70° N. All stations included in the study have contiguous coverage of 18 years or more with 1-min resolution data. As expected, the EVA shows that the higher latitude stations have higher probability of large |dBh/dt| and |Eh| compared to stations further south. However, the EVA also shows that the shape of the distribution changes with magnetic latitude. The high latitudes have distributions that fall off faster to zero than the low latitudes, and upward bounded distributions can not be ruled out. The transition occurs around 59-61° N magnetic latitudes. Thus, the EVA shows that the observed series north of ≈ 60° N have already measured values that are close to the expected maxima values, while stations south of ≈ ° N will measure larger values in the future.

  16. Flexible Dielectric Nanocomposites with Ultrawide Zero-Temperature Coefficient Windows for Electrical Energy Storage and Conversion under Extreme Conditions.

    PubMed

    Shehzad, Khurram; Xu, Yang; Gao, Chao; Li, Hanying; Dang, Zhi-Min; Hasan, Tawfique; Luo, Jack; Duan, Xiangfeng

    2017-03-01

    Polymer dielectrics offer key advantages over their ceramic counterparts such as flexibility, scalability, low cost, and high breakdown voltages. However, a major drawback that limits more widespread application of polymer dielectrics is their temperature-dependent dielectric properties. Achieving dielectric constants with low/zero-temperature coefficient (L/0TC) over a broad temperature range is essential for applications in diverse technologies. Here, we report a hybrid filler strategy to produce polymer composites with an ultrawide L/0TC window of dielectric constant, as well as a significantly enhanced dielectric value, maximum energy storage density, thermal conductivity, and stability. By creating a series of percolative polymer composites, we demonstrated hybrid carbon filler based composites can exhibit a zero-temperature coefficient window of 200 °C (from -50 to 150 °C), the widest 0TC window for all polymer composite dielectrics reported to date. We further show the electric and dielectric temperature coefficient of the composites is highly stable against stretching and bending, even under AC electric field with frequency up to 1 MHz. We envision that our method will push the functional limits of polymer dielectrics for flexible electronics in extreme conditions such as in hybrid vehicles, aerospace, power electronics, and oil/gas exploration.

  17. Recent early clinical drug development for acute kidney injury.

    PubMed

    Gallagher, Kevin M; O'neill, Stephen; Harrison, Ewen M; Ross, James A; Wigmore, Stephen J; Hughes, Jeremy

    2017-02-01

    Despite significant need and historical trials, there are no effective drugs in use for the prevention or treatment of acute kidney injury (AKI). There are several promising agents in early clinical development for AKI and two trials have recently been terminated. There are also exciting new findings in pre-clinical AKI research. There is a need to take stock of current progress in the field to guide future drug development for AKI. Areas covered: The main clinical trial registries, PubMed and pharmaceutical company website searches were used to extract the most recent clinical trials for sterile, transplant and sepsis-associated AKI. We summarise the development of the agents recently in clinical trial, update on their trial progress, consider reasons for failed efficacy of two agents, and discuss new paradigms in pre-clinical targets for AKI. Agents covered include- QPI-1002, THR-184, BB-3, heme arginate, human recombinant alkaline phosphatase (recAP), ciclosporin A, AB103, levosimendan, AC607 and ABT-719. Expert opinion: Due to the heterogenous nature of AKI, agents with the widest pleiotropic effects on multiple pathophysiological pathways are likely to be most effective. Linking preclinical models to clinical indication and improving AKI definition and diagnosis are key areas for improvement in future clinical trials.

  18. High but not dry: diverse epiphytic bromeliad adaptations to exposure within a seasonally dry tropical forest community.

    PubMed

    Reyes-García, C; Mejia-Chang, M; Griffiths, H

    2012-02-01

    • Vascular epiphytes have developed distinct lifeforms to maximize water uptake and storage, particularly when delivered as pulses of precipitation, dewfall or fog. The seasonally dry forest of Chamela, Mexico, has a community of epiphytic bromeliads with Crassulacean acid metabolism showing diverse morphologies and stratification within the canopy. We hypothesize that niche differentiation may be related to the capacity to use fog and dew effectively to perform photosynthesis and to maintain water status. • Four Tillandsia species with either 'tank' or 'atmospheric' lifeforms were studied using seasonal field data and glasshouse experimentation, and compared on the basis of water use, leaf water δ(18) O, photosynthetic and morphological traits. • The atmospheric species, Tillandsia eistetteri, with narrow leaves and the lowest succulence, was restricted to the upper canopy, but displayed the widest range of physiological responses to pulses of precipitation and fog, and was a fog-catching 'nebulophyte'. The other atmospheric species, Tillandsia intermedia, was highly succulent, restricted to the lower canopy and with a narrower range of physiological responses. Both upper canopy tank species relied on tank water and stomatal closure to avoid desiccation. • Niche differentiation was related to capacity for water storage, dependence on fog or dewfall and physiological plasticity. © 2011 The Authors. New Phytologist © 2011 New Phytologist Trust.

  19. Graphene toxicity as a double-edged sword of risks and exploitable opportunities: a critical analysis of the most recent trends and developments

    NASA Astrophysics Data System (ADS)

    Volkov, Yuri; McIntyre, Jennifer; Prina-Mello, Adriele

    2017-06-01

    Increased production volumes and a broadening application spectrum of graphene have raised concerns about its potential adverse effects on human health. Numerous reports demonstrate that graphene irrespective of its particular form exerts its effects on a widest range of living organisms, including prokaryotic bacteria and viruses, plants, micro- and macro-invertebrates, mammalian and human cells and whole animals in vivo. However, the available experimental data is frequently a matter of significant divergence and even controversy. Therefore, we provide here a critical analysis of the most recent (2015-2016) reports accumulated in the graphene-related materials biocompatibility and toxicology field in order to elucidate the cutting edge achievements, emerging trends and future opportunities in the area. Experimental findings from the diverse in vitro and in vivo model systems are analysed in the context of the most likely graphene exposure scenarios, such as respiratory inhalation, ingestion route, parenteral administration and topical exposure through the skin. Key factors influencing the toxicity of graphene and its complex derivatives as well as potential risk mitigation approaches exploiting graphene physicochemical properties, surface modifications and possible degradation pathways are also discussed along with its emerging applications for healthcare, diagnostics and innovative therapeutic approaches.

  20. This Month in Astronomical History: Preliminary Survey Results

    NASA Astrophysics Data System (ADS)

    Wilson, Teresa

    2017-01-01

    This Month in Astronomical History is a short (~500 word) column on the AAS website that revisits significant astronomical events or the lives of people who have made a large impact on the field. The monthly column began in July 2016 at the request of the Historical Astronomical Division. Examples of topics that have been covered include Comet Shoemaker-Levy’s collision with Jupiter, the discovery of the moons of Mars, the life of Edwin Hubble, Maria Mitchell’s comet discovery, and the launch of Sputnik II. A survey concerning the column is in progress to ensure the column addresses the interests and needs of a broad readership, including historians, educators, research astronomers, and the general public. Eleven questions focus on the style and content of the column, while eight collect simple demographics. The survey has been available on the AAS website since and was mentioned in several AAS newsletters; however, non-members of AAS were also recruited to include respondents from a variety of backgrounds. Preliminary results of the survey are presented and will be used to hone the style and content of the column to serve the widest possible audience. Responses continue to be collected at: https://goo.gl/forms/Lhwl2aWJl2Vkoo7v1

  1. Seasonal fluctuation in the neuronal classes of parahippocampal area of P. krameri (Scopoli, 1769) and E. scolopaceus (Linnaeus, 1758).

    PubMed

    Srivastava, U C; Singh, S; Singh, D

    2012-10-08

    Hippocampus in birds is a relatively narrow, curved strip of tissue that lies on the dorsomedial surface of telencephalon. It is widest dorsally at the junction with parahippocampal area, and it tapers with septum. Parahippocampal area (APH), the most prominent field of hippocampus is a long structure that lies at the most rostral level and continues upto caudal extent. It has been indicated by behavioral studies that hippocampus in birds plays an important role in process of learning, memory formation, food storage and spatial navigation. The present study enlightens some interesting fluctuations occurring in the neuronal classes of parahippocampal area of two seasonally breeding birds viz. P. krameri and E. scolopaceus in terms of dendritic thickness, spine density and spine morphology during breeding and non-breeding time period of birds. The Golgi-impregnated sections were used to study these fluctuations and it was noticed that there was a significant increase in dendritic thickness, spine density, spine length and spine head diameter during breeding as compared to non-breeding period. The results obtained were comparable in two different seasonally breeding birds, supporting the view that avian parahippocampal area shows neuroanatomical plasticity associated with breeding and non-breeding period because of variations in endocrinology.

  2. Clutch and egg allometry of the turtle Mauremys leprosa (Chelonia: Geoemydidae) from a polluted peri-urban river in west-central Morocco

    USGS Publications Warehouse

    Naimi, Mohamed; Znari, Mohammed; Lovich, Jeffrey E.; Feddadi, Youssef; Baamrane, Moulay Abdeljalil Ait

    2012-01-01

    We examined the relationships of clutch size (CS) and egg size to female body size (straight-line carapace length, CL) in a population of the turtle Mauremys leprosa from a polluted segment of oued (river) Tensift in arid west-central Morocco. Twenty-eight adult females were collected in May–July, 2009 and all were gravid. Each was weighed, measured, humanely euthanized and then dissected. Oviductal shelled eggs were removed, weighed (egg mass, EM) and measured for length (EL) and width (EW). Clutch mass (CM) was the sum of EM for a clutch. Pelvic aperture width (PAW) was measured at the widest point between the ilia bones through which eggs must pass at oviposition. The smallest gravid female had a CL of 124.0 mm. Mean CS was relatively large (9.7±2.0 eggs, range: 3–13) and may reflect high productivity associated with polluted (eutrophic) waters. Regression analyses were conducted using log-transformed data. CM increased isometrically with maternal body size. CS, EW and EM were all significantly hypoallometric in their relationship with CL. EL did not change significantly with increases in CL. EW increased at a hypoallometric rate with increasing CL but was unconstrained by PAW since the widest egg was smaller than the narrowest PAW measurement when excluding the three smallest females. Smaller females may have EW constrained by PAW. As females increase in size they increase both clutch size and egg width in contradiction to predictions of optimal egg size theory.

  3. Shape optimization of solid-air porous phononic crystal slabs with widest full 3D bandgap for in-plane acoustic waves

    NASA Astrophysics Data System (ADS)

    D'Alessandro, Luca; Bahr, Bichoy; Daniel, Luca; Weinstein, Dana; Ardito, Raffaele

    2017-09-01

    The use of Phononic Crystals (PnCs) as smart materials in structures and microstructures is growing due to their tunable dynamical properties and to the wide range of possible applications. PnCs are periodic structures that exhibit elastic wave scattering for a certain band of frequencies (called bandgap), depending on the geometric and material properties of the fundamental unit cell of the crystal. PnCs slabs can be represented by plane-extruded structures composed of a single material with periodic perforations. Such a configuration is very interesting, especially in Micro Electro-Mechanical Systems industry, due to the easy fabrication procedure. A lot of topologies can be found in the literature for PnCs with square-symmetric unit cell that exhibit complete 2D bandgaps; however, due to the application demand, it is desirable to find the best topologies in order to guarantee full bandgaps referred to in-plane wave propagation in the complete 3D structure. In this work, by means of a novel and fast implementation of the Bidirectional Evolutionary Structural Optimization technique, shape optimization is conducted on the hole shape obtaining several topologies, also with non-square-symmetric unit cell, endowed with complete 3D full bandgaps for in-plane waves. Model order reduction technique is adopted to reduce the computational time in the wave dispersion analysis. The 3D features of the PnC unit cell endowed with the widest full bandgap are then completely analyzed, paying attention to engineering design issues.

  4. The Widest-separation Substellar Companion Candidate to a Binary T Tauri Star

    NASA Astrophysics Data System (ADS)

    Kuzuhara, M.; Tamura, M.; Ishii, M.; Kudo, T.; Nishiyama, S.; Kandori, R.

    2011-04-01

    The results of near-infrared imaging and spectroscopy of a substellar companion (SR12 C), with a possible planetary mass, of a binary T Tauri star (SR12 AB) in the ρ Ophiuchi star-forming region are presented. The object is separated by ~8farcs7, corresponding to ~1100 AU at 125 pc, and has an H-band brightness of 15.2 mag and infrared spectra suggesting a spectral type of M9.0 ± 0.5. It is confirmed that SR12 C is physically related to the ρ Ophiuchi star-forming region from its common proper motion with SR12 AB and its youth is confirmed by a gravity-sensitive spectral feature. Furthermore, based on the number of known members of the ρ Ophiuchi star-forming region in the area in which SR12 AB exists, the probability of a chance alignment is ~1% and it is therefore likely that SR12 C is physically associated with SR12 AB. The mass of SR12 C is estimated by comparing its estimated luminosity and assumed age with the theoretical age-luminosity relation. SR12 C is identified as an extremely low-mass (0.013 ± 0.007 M sun) object, but its separation from its parent star is the widest among planetary-mass companion (PMC) candidates imaged to date. In addition, SR12 C is the first PMC candidate directly imaged around a binary star. This discovery suggests that PMCs form via multiple star formation processes including disk gravitational instability and cloud core fragmentation.

  5. Development and Performance of a Highly Sensitive Model Formulation Based on Torasemide to Enhance Hot-Melt Extrusion Process Understanding and Process Development.

    PubMed

    Evans, Rachel C; Kyeremateng, Samuel O; Asmus, Lutz; Degenhardt, Matthias; Rosenberg, Joerg; Wagner, Karl G

    2018-05-01

    The aim of this work was to investigate the use of torasemide as a highly sensitive indicator substance and to develop a formulation thereof for establishing quantitative relationships between hot-melt extrusion process conditions and critical quality attributes (CQAs). Using solid-state characterization techniques and a 10 mm lab-scale co-rotating twin-screw extruder, we studied torasemide in a Soluplus® (SOL)-polyethylene glycol 1500 (PEG 1500) matrix, and developed and characterized a formulation which was used as a process indicator to study thermal- and hydrolysis-induced degradation, as well as residual crystallinity. We found that torasemide first dissolved into the matrix and then degraded. Based on this mechanism, extrudates with measurable levels of degradation and residual crystallinity were produced, depending strongly on the main barrel and die temperature and residence time applied. In addition, we found that 10% w/w PEG 1500 as plasticizer resulted in the widest operating space with the widest range of measurable residual crystallinity and degradant levels. Torasemide as an indicator substance behaves like a challenging-to-process API, only with higher sensitivity and more pronounced effects, e.g., degradation and residual crystallinity. Application of a model formulation containing torasemide will enhance the understanding of the dynamic environment inside an extruder and elucidate the cumulative thermal and hydrolysis effects of the extrusion process. The use of such a formulation will also facilitate rational process development and scaling by establishing clear links between process conditions and CQAs.

  6. A Simple and Reliable Technique to Orient Donor Corneal Tissue Using the Radial Width of the Surgical Limbus.

    PubMed

    Aldrich, Benjamin T; Stockman, Adam M; Freiburger, Monica J; Shinkunas, Todd J; Burckart, Kimberlee A; Schmidt, Gregory A; Reed, Cynthia R; Zimmerman, M Bridget; Goins, Kenneth M; Wagoner, Michael D; Greiner, Mark A

    2015-12-01

    To develop a method based on identification of the widest region of the surgical limbus that can yield quick and accurate orientation of excised human donor corneas. Corneoscleral tissue from donors 49 to 75 years old was marked at the temporal sclera at the time of recovery. Digital images obtained from 20 corneas stored in viewing chambers, retroilluminated and viewed from the endothelial side, were used to quantify the per-degree radial width of the surgical limbus, defined as the distance from the scleral spur to clear cornea. To evaluate differences in radial width among regions, measurements were compared with the intracorneal mean limbal width, and a per-degree z-score was calculated by averaging among corneas. Using images of corneas with the temporal mark masked and the sidedness known, 6 observers were subjected to a blinded trial of 10 corneas to determine the central point of the widest limbal region of each cornea. Compared with the intracorneal mean, the mean radial width of the surgical limbus was greatest in the superior quadrant, and the difference compared with the inferior, nasal, and temporal quadrants was significant (P < 0.0001). The superior region was identified with 100% accuracy in blinded trials. The average absolute difference between the predicted and actual central point of the superior limbus was 9.75 ± 0.30 degrees. The radial width of the surgical limbus is greatest in the superior region of the cornea and can be used as a diagnostic feature to orient donor corneal tissue.

  7. 77 FR 47907 - Montana Disaster #MT-00067

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... the disaster: Primary Counties: Rosebud. Contiguous Counties: Montana: Big Horn, Custer, Garfield....938 Businesses With Credit Available Elsewhere 6.000 Businesses Without Credit Available Elsewhere 4...

  8. 75 FR 27009 - Tennessee Disaster Number TN-00039

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ..., Houston, Madison, Obion. Contiguous Counties: (Economic Injury Loans Only): Tennessee: Henry, Weakley... remains unchanged. (Catalog of Federal Domestic Assistance Numbers 59002 and 59008) James E. Rivera...

  9. Active membrane having uniform physico-chemically functionalized ion channels

    DOEpatents

    Gerald, II, Rex E; Ruscic, Katarina J; Sears, Devin N; Smith, Luis J; Klingler, Robert J; Rathke, Jerome W

    2012-09-24

    The present invention relates to a physicochemically-active porous membrane for electrochemical cells that purports dual functions: an electronic insulator (separator) and a unidirectional ion-transporter (electrolyte). The electrochemical cell membrane is activated for the transport of ions by contiguous ion coordination sites on the interior two-dimensional surfaces of the trans-membrane unidirectional pores. One dimension of the pore surface has a macroscopic length (1 nm-1000 .mu.m) and is directed parallel to the direction of an electric field, which is produced between the cathode and the anode electrodes of an electrochemical cell. The membrane material is designed to have physicochemical interaction with ions. Control of the extent of the interactions between the ions and the interior pore walls of the membrane and other materials, chemicals, or structures contained within the pores provides adjustability of the ionic conductivity of the membrane.

  10. AlGaAs heterojunction lasers

    NASA Technical Reports Server (NTRS)

    Goldstein, B.; Pultz, G. N.; Carlin, D. B.; Slavin, S. E.; Ettenberg, M.

    1988-01-01

    The characterization of 8300 A lasers was broadened, especially in the area of beam quality. Modulation rates up to 2 Gbit/sec at output powers of 20 mW were observed, waveform fidelity was fully adequate for low BER data transmission, and wavefront measurements showed that phase aberrations were less than lamda/50. Also, individually addressable arrays of up to ten contiguous diode lasers were fabricated and tested. Each laser operates at powers up to 30 mW CW in single spatial mode. Shifting the operating wavelength of the basic CSP laser from 8300 A to 8650 A was accomplished by the addition of Si to the active region. Output power has reached 100 mW single mode, with excellent far field wave front properties. Operating life is currently approx. 1000 hrs at 35 mW CW. In addition, laser reliability, for operation at both 8300 A and 8650 A, has profited significantly from several developments in the processing procedures.

  11. Organocatalytic asymmetric arylation of indoles enabled by azo groups

    NASA Astrophysics Data System (ADS)

    Qi, Liang-Wen; Mao, Jian-Hui; Zhang, Jian; Tan, Bin

    2018-01-01

    Arylation is a fundamental reaction that can be mostly fulfilled by electrophilic aromatic substitution and transition-metal-catalysed aryl functionalization. Although the azo group has been used as a directing group for many transformations via transition-metal-catalysed aryl carbon-hydrogen (C-H) bond activation, there remain significant unmet challenges in organocatalytic arylation. Here, we show that the azo group can effectively act as both a directing and activating group for organocatalytic asymmetric arylation of indoles via formal nucleophilic aromatic substitution of azobenzene derivatives. Thus, a wide range of axially chiral arylindoles have been achieved in good yields with excellent enantioselectivities by utilizing chiral phosphoric acid as catalyst. Furthermore, highly enantioenriched pyrroloindoles bearing two contiguous quaternary chiral centres have also been obtained via a cascade enantioselective formal nucleophilic aromatic substitution-cyclization process. This strategy should be useful in other related research fields and will open new avenues for organocatalytic asymmetric aryl functionalization.

  12. Organocatalytic asymmetric arylation of indoles enabled by azo groups.

    PubMed

    Qi, Liang-Wen; Mao, Jian-Hui; Zhang, Jian; Tan, Bin

    2018-01-01

    Arylation is a fundamental reaction that can be mostly fulfilled by electrophilic aromatic substitution and transition-metal-catalysed aryl functionalization. Although the azo group has been used as a directing group for many transformations via transition-metal-catalysed aryl carbon-hydrogen (C-H) bond activation, there remain significant unmet challenges in organocatalytic arylation. Here, we show that the azo group can effectively act as both a directing and activating group for organocatalytic asymmetric arylation of indoles via formal nucleophilic aromatic substitution of azobenzene derivatives. Thus, a wide range of axially chiral arylindoles have been achieved in good yields with excellent enantioselectivities by utilizing chiral phosphoric acid as catalyst. Furthermore, highly enantioenriched pyrroloindoles bearing two contiguous quaternary chiral centres have also been obtained via a cascade enantioselective formal nucleophilic aromatic substitution-cyclization process. This strategy should be useful in other related research fields and will open new avenues for organocatalytic asymmetric aryl functionalization.

  13. A unified high-resolution wind and solar dataset from a rapidly updating numerical weather prediction model

    DOE PAGES

    James, Eric P.; Benjamin, Stanley G.; Marquis, Melinda

    2016-10-28

    A new gridded dataset for wind and solar resource estimation over the contiguous United States has been derived from hourly updated 1-h forecasts from the National Oceanic and Atmospheric Administration High-Resolution Rapid Refresh (HRRR) 3-km model composited over a three-year period (approximately 22 000 forecast model runs). The unique dataset features hourly data assimilation, and provides physically consistent wind and solar estimates for the renewable energy industry. The wind resource dataset shows strong similarity to that previously provided by a Department of Energy-funded study, and it includes estimates in southern Canada and northern Mexico. The solar resource dataset represents anmore » initial step towards application-specific fields such as global horizontal and direct normal irradiance. This combined dataset will continue to be augmented with new forecast data from the advanced HRRR atmospheric/land-surface model.« less

  14. Biosensoric potential of microbial fuel cells.

    PubMed

    Schneider, György; Kovács, Tamás; Rákhely, Gábor; Czeller, Miklós

    2016-08-01

    Recent progress in microbial fuel cell (MFC) technology has highlighted the potential of these devices to be used as biosensors. The advantages of MFC-based biosensors are that they are phenotypic and can function in either assay- or flow-through formats. These features make them appropriate for contiguous on-line monitoring in laboratories and for in-field applications. The selectivity of an MFC biosensor depends on the applied microorganisms in the anodic compartment where electron transfer (ET) between the artificial surface (anode) and bacterium occurs. This process strongly determines the internal resistance of the sensoric system and thus influences signal outcome and response time. Despite their beneficial characteristics, the number of MFC-based biosensoric applications has been limited until now. The aim of this mini-review is to turn attention to the biosensoric potential of MFCs by summarizing ET mechanisms on which recently established and future sensoric devices are based.

  15. Potential effects of global warming on the distribution of a temperate univoltine insect

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rooney, T.P.; Hurd, L.E.

    1993-06-01

    Poleward migration to remain within temperature tolerance ranges as the earth warms poses a problem for species with limited dispersal abilities. The life cycle of a typical temperate univoltine insect, Tenodera sinensis (Mantodea: Mantidae), is constrained by degree-days per season: too few prevent maturation before killing frost in the fall; too many allow egg hatch prior to killing frost. We combined field observations of dispersal ability with laboratory measurements of the relationship between temperature and maturation rate, and applied these to a global warming model to predict the effect of climate change on regional distribution of this insect by 2100more » A.D. Based on the simplified biological assumptions of our model, T, sinensis would be reduced to local populations in the northern portions and higher elevations of its present broadly contiguous range, and species with similar life histories may face regional or total extinction.« less

  16. SLITHER: a web server for generating contiguous conformations of substrate molecules entering into deep active sites of proteins or migrating through channels in membrane transporters.

    PubMed

    Lee, Po-Hsien; Kuo, Kuei-Ling; Chu, Pei-Ying; Liu, Eric M; Lin, Jung-Hsin

    2009-07-01

    Many proteins use a long channel to guide the substrate or ligand molecules into the well-defined active sites for catalytic reactions or for switching molecular states. In addition, substrates of membrane transporters can migrate to another side of cellular compartment by means of certain selective mechanisms. SLITHER (http://bioinfo.mc.ntu.edu.tw/slither/or http://slither.rcas.sinica.edu.tw/) is a web server that can generate contiguous conformations of a molecule along a curved tunnel inside a protein, and the binding free energy profile along the predicted channel pathway. SLITHER adopts an iterative docking scheme, which combines with a puddle-skimming procedure, i.e. repeatedly elevating the potential energies of the identified global minima, thereby determines the contiguous binding modes of substrates inside the protein. In contrast to some programs that are widely used to determine the geometric dimensions in the ion channels, SLITHER can be applied to predict whether a substrate molecule can crawl through an inner channel or a half-channel of proteins across surmountable energy barriers. Besides, SLITHER also provides the list of the pore-facing residues, which can be directly compared with many genetic diseases. Finally, the adjacent binding poses determined by SLITHER can also be used for fragment-based drug design.

  17. [Coupling between ecological vulnerability and economic poverty in contiguous destitute areas, China: Empirical analysis of 714 poverty-stricken counties.

    PubMed

    Cao, Shi Song; Wang, Yan Hui; Duan, Fu Zhou; Zhao, Wen Ji; Wang, Zhi Heng; Fang, Na

    2016-08-01

    Maintaining the coordinated correlation between ecological environment and economic development is one of the important strategies in the new stage of poverty alleviation and development. Taking 714 poverty-stricken counties in contiguous destitute areas as study areas, this paper designed the ecological vulnerability evaluation indicator system based on the ecological sensitivity-resilience-pressure (SRP) conceptual model, as well as the comprehensive poverty evaluation indicators from the perspective of socioeconomic development, so as to build the coupling model to reveal the coupling between ecological vulnerability and economic poverty. The results showed that Hu-Line could act as a feasible partition label to depict the spatial distribution patterns of ecological vulnerability, economic poverty, as well as their coupling degree in contiguous destitute areas, which should be fully taken into consideration the influence of Hu-Line on the east-west pattern classification of national poverty reduction. In addition, there existed a symbiotic positive correlation between ecological vulnerability and economic poverty, therefore, the strategic significance of ecological and environment protection in poverty-stricken areas should be specifically emphasized to reduce economic poverty by synchronously protecting the ecological environment. Approximately half of the counties involved in the study area were in the coordinated type of recession disorders, where the ecological environment quality and the economic development could not be synchronized.

  18. A hybrid approach to estimating national scale spatiotemporal variability of PM2.5 in the contiguous United States.

    PubMed

    Beckerman, Bernardo S; Jerrett, Michael; Serre, Marc; Martin, Randall V; Lee, Seung-Jae; van Donkelaar, Aaron; Ross, Zev; Su, Jason; Burnett, Richard T

    2013-07-02

    Airborne fine particulate matter exhibits spatiotemporal variability at multiple scales, which presents challenges to estimating exposures for health effects assessment. Here we created a model to predict ambient particulate matter less than 2.5 μm in aerodynamic diameter (PM2.5) across the contiguous United States to be applied to health effects modeling. We developed a hybrid approach combining a land use regression model (LUR) selected with a machine learning method, and Bayesian Maximum Entropy (BME) interpolation of the LUR space-time residuals. The PM2.5 data set included 104,172 monthly observations at 1464 monitoring locations with approximately 10% of locations reserved for cross-validation. LUR models were based on remote sensing estimates of PM2.5, land use and traffic indicators. Normalized cross-validated R(2) values for LUR were 0.63 and 0.11 with and without remote sensing, respectively, suggesting remote sensing is a strong predictor of ground-level concentrations. In the models including the BME interpolation of the residuals, cross-validated R(2) were 0.79 for both configurations; the model without remotely sensed data described more fine-scale variation than the model including remote sensing. Our results suggest that our modeling framework can predict ground-level concentrations of PM2.5 at multiple scales over the contiguous U.S.

  19. Correlation of microstructure with dynamic deformation behavior and penetration performance of tungsten heavy alloys fabricated by mechanical alloying

    NASA Astrophysics Data System (ADS)

    Kim, Dong-Kuk; Lee, Sunghak; Ryu, Ho Jin; Hyunghong, Soon; Noh, Joon-Woong

    2000-10-01

    In this study, tungsten heavy alloy specimens were fabricated by mechanical alloying (MA), and their dynamic torsional properties and penetration performance were investigated. Dynamic torsional tests were conducted on the specimens fabricated with different sintering temperatures after MA, and then the test data were compared with those of a conventionally processed specimen. Refinement of tungsten particles was obtained after MA, but contiguity was seriously increased, thereby leading to low ductility and impact energy. Specimens in which both particle size and contiguity were simultaneously reduced by MA and two-step sintering and those having higher matrix fraction by partial MA were successfully fabricated. The dynamic test results indicated that the formation of adiabatic shear bands was expected because of the plastic localization at the central area of the gage section. Upon highspeed impact testing of these specimens, self-sharpening was promoted by the adiabatic shear band formation, but their penetration performance did not improve since much of kinetic energy of the penetrators was consumed for the microcrack formation due to interfacial debonding and cleavage fracture of tungsten particles. In order to improve penetration performance as well as to achieve selfsharpening by applying MA, conditions of MA and sintering process should be established so that alloy densification, particle refinement, and contiguity reduction can be simultaneously achieved.

  20. [Coupling coordination evaluation method between eco-environment quality and economic development level in contiguous special poverty-stricken areas of China].

    PubMed

    Wang, Yan-hui; Li, Jing-yi

    2015-05-01

    It is one of the important strategies in the new period of national poverty alleviation and development to maintain the basic balance between the ecological environment and economic development, and to promote the coordinated sustainable development of economy and ecological environment. Taking six contiguous special poverty-stricken areas as the study areas, a coupling coordination evaluation method between eco-environment quality and economic development level in contiguous special poverty-stricken areas was explored in this paper. The region' s ecological poverty index system was proposed based on the natural attribute of ecological environment, and the ecological environment quality evaluation method was built up by using AHP weighting method, followed by the design of the coupling coordination evaluation method between the ecological environment indices and the county economic poverty comprehensive indices. The coupling coordination degrees were calculated and their spatial representation differentiations were analyzed respectively at district, province, city, and county scales. Results showed that approximately half of the counties in the study areas achieved the harmoniously coordinated development. However, the ecological environmental quality and the economic development in most counties could not be synchronized, where mountains, rivers and other geographic features existed roughly as a dividing line of the coordinated development types. The phenomena of dislocation between the ecological environment and economic development in state-level poor counties were more serious than those of local poor counties.

  1. Chimeric mitochondrial peptides from contiguous regular and swinger RNA.

    PubMed

    Seligmann, Hervé

    2016-01-01

    Previous mass spectrometry analyses described human mitochondrial peptides entirely translated from swinger RNAs, RNAs where polymerization systematically exchanged nucleotides. Exchanges follow one among 23 bijective transformation rules, nine symmetric exchanges (X ↔ Y, e.g. A ↔ C) and fourteen asymmetric exchanges (X → Y → Z → X, e.g. A → C → G → A), multiplying by 24 DNA's protein coding potential. Abrupt switches from regular to swinger polymerization produce chimeric RNAs. Here, human mitochondrial proteomic analyses assuming abrupt switches between regular and swinger transcriptions, detect chimeric peptides, encoded by part regular, part swinger RNA. Contiguous regular- and swinger-encoded residues within single peptides are stronger evidence for translation of swinger RNA than previously detected, entirely swinger-encoded peptides: regular parts are positive controls matched with contiguous swinger parts, increasing confidence in results. Chimeric peptides are 200 × rarer than swinger peptides (3/100,000 versus 6/1000). Among 186 peptides with > 8 residues for each regular and swinger parts, regular parts of eleven chimeric peptides correspond to six among the thirteen recognized, mitochondrial protein-coding genes. Chimeric peptides matching partly regular proteins are rarer and less expressed than chimeric peptides matching non-coding sequences, suggesting targeted degradation of misfolded proteins. Present results strengthen hypotheses that the short mitogenome encodes far more proteins than hitherto assumed. Entirely swinger-encoded proteins could exist.

  2. Engineering on-chip nanoporous gold material libraries via precision photothermal treatment

    NASA Astrophysics Data System (ADS)

    Chapman, Christopher A. R.; Wang, Ling; Biener, Juergen; Seker, Erkin; Biener, Monika M.; Matthews, Manyalibo J.

    2015-12-01

    Libraries of nanostructured materials on a single chip are a promising platform for high throughput and combinatorial studies of structure-property relationships in the fields of physics and biology. Nanoporous gold (np-Au), produced by an alloy corrosion process, is a nanostructured material specifically suited for such studies because of its self-similar thermally induced coarsening behavior. However, traditional heat application techniques for the modification of np-Au are bulk processes that cannot be used to generate a library of different pore sizes on a single chip. Here, laser micro-processing offers an attractive solution to this problem by providing a means to apply energy with high spatial and temporal resolution. In the present study we use finite element multiphysics simulations to predict the effects of laser mode (continuous-wave vs. pulsed) and thermal conductivity of the supporting substrate on the local np-Au film temperatures during photothermal annealing. Based on these results we discuss the mechanisms by which the np-Au network is coarsened. Thermal transport simulations predict that continuous-wave mode laser irradiation of np-Au thin films on a silicon substrate supports the widest range of morphologies that can be created through photothermal annealing of np-Au. Using the guidance provided by simulations, we successfully fabricate an on-chip material library consisting of 81 np-Au samples of 9 different morphologies for use in the parallel study of structure-property relationships.Libraries of nanostructured materials on a single chip are a promising platform for high throughput and combinatorial studies of structure-property relationships in the fields of physics and biology. Nanoporous gold (np-Au), produced by an alloy corrosion process, is a nanostructured material specifically suited for such studies because of its self-similar thermally induced coarsening behavior. However, traditional heat application techniques for the modification of np-Au are bulk processes that cannot be used to generate a library of different pore sizes on a single chip. Here, laser micro-processing offers an attractive solution to this problem by providing a means to apply energy with high spatial and temporal resolution. In the present study we use finite element multiphysics simulations to predict the effects of laser mode (continuous-wave vs. pulsed) and thermal conductivity of the supporting substrate on the local np-Au film temperatures during photothermal annealing. Based on these results we discuss the mechanisms by which the np-Au network is coarsened. Thermal transport simulations predict that continuous-wave mode laser irradiation of np-Au thin films on a silicon substrate supports the widest range of morphologies that can be created through photothermal annealing of np-Au. Using the guidance provided by simulations, we successfully fabricate an on-chip material library consisting of 81 np-Au samples of 9 different morphologies for use in the parallel study of structure-property relationships. Electronic supplementary information (ESI) available: Details of sample preparation, fabrication of material libraries, as well as further analysis and supporting scanning electron micrographs can be found in ESI. See DOI: 10.1039/c5nr04580k

  3. 75 FR 51119 - Kentucky Disaster Number KY-00035

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... Loans): Madison, Mason, Rowan. Contiguous Counties: (Economic Injury Loans Only): Kentucky: Bath... Assistance Numbers 59002 and 59008) James E. Rivera, Associate Administrator for Disaster Assistance. [FR Doc...

  4. Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

    ClinicalTrials.gov

    2018-05-16

    Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Promyelocytic Leukemia (M3); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma; Anaplastic Large Cell Lymphoma; B-cell Adult Acute Lymphoblastic Leukemia; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cytomegalovirus Infection; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Isolated Plasmacytoma of Bone; Monoclonal Gammopathy of Undetermined Significance; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Peripheral T-cell Lymphoma; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Central Nervous System Hodgkin Lymphoma; Primary Central Nervous System Non-Hodgkin Lymphoma; Primary Myelofibrosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Multiple Myeloma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Large Granular Lymphocyte Leukemia; Untreated Adult Acute Myeloid Leukemia; Untreated Hairy Cell Leukemia; Waldenström Macroglobulinemia

  5. Adaptive Kalman filtering for real-time mapping of the visual field

    PubMed Central

    Ward, B. Douglas; Janik, John; Mazaheri, Yousef; Ma, Yan; DeYoe, Edgar A.

    2013-01-01

    This paper demonstrates the feasibility of real-time mapping of the visual field for clinical applications. Specifically, three aspects of this problem were considered: (1) experimental design, (2) statistical analysis, and (3) display of results. Proper experimental design is essential to achieving a successful outcome, particularly for real-time applications. A random-block experimental design was shown to have less sensitivity to measurement noise, as well as greater robustness to error in modeling of the hemodynamic impulse response function (IRF) and greater flexibility than common alternatives. In addition, random encoding of the visual field allows for the detection of voxels that are responsive to multiple, not necessarily contiguous, regions of the visual field. Due to its recursive nature, the Kalman filter is ideally suited for real-time statistical analysis of visual field mapping data. An important feature of the Kalman filter is that it can be used for nonstationary time series analysis. The capability of the Kalman filter to adapt, in real time, to abrupt changes in the baseline arising from subject motion inside the scanner and other external system disturbances is important for the success of clinical applications. The clinician needs real-time information to evaluate the success or failure of the imaging run and to decide whether to extend, modify, or terminate the run. Accordingly, the analytical software provides real-time displays of (1) brain activation maps for each stimulus segment, (2) voxel-wise spatial tuning profiles, (3) time plots of the variability of response parameters, and (4) time plots of activated volume. PMID:22100663

  6. Plausible Boosting of Millimeter-Galaxies in the COSMOS Field by Intervening Large-Scale Structure

    NASA Astrophysics Data System (ADS)

    Aretxaga, I.; Wilson, G. W.; Aguilar, E.; Alberts, S.; Scott, K. S.; Scoville, N.; Yun, M. S.; Austermann, J.; Downes, T. D.; Ezawa, H.; Hatsukade, B.; Hughes, D. H.; Kawabe, R.; Kohno, K.; Oshima, T.; Perera, T. A.; Tamura, Y.; Zeballos, M.

    2011-10-01

    The 0.72 sq. deg. contiguous 1.1mm survey in the central area of the COSMOS field, carried out to a 1σ≍1.26 mJy beam-1 depth with the AzTEC camera mounted on the 10m Atacama Submillimeter Telescope Experiment (ASTE), shows number counts with a significant excess of sources when compared to the number counts derived from the ˜0.5 sq. deg. area sampled at similar depths in the Scuba HAlf Degree Extragalactic Survey (SHADES, Austermann et al. 2010). They are, however, consistent with those derived from fields that were considered too small to characterize the overall blank-field population. We identify differences to be more significant in the S1.1mm ˜> 5 mJy regime, and demonstrate that these excesses in number counts are related to the areas where galaxies at redshifts ˜< 1.1 are more densely clustered. The positions of optical-IR galaxies in the redshift interval 0.6 ˜< z ˜< 0.75 are the ones that show the strongest correlation with the positions of the 1.1mm bright population (S1.mm ˜>5 mJy), a result which does not depend exclusively on the presence of rich clusters within the survey sampled area. The most likely explanation for the observed excess in number counts at 1.1mm is galaxy-galaxy and galaxy-group lensing at moderate amplification levels, that increases in amplitude as one samples larger and larger flux densities.

  7. VizieR Online Data Catalog: Morphologies of selected AGN (Griffith+, 2010)

    NASA Astrophysics Data System (ADS)

    Griffith, R. L.; Stern, D.

    2012-06-01

    The cornerstone data set for the COSMOS survey is its wide-field HST Advanced Camera for Surveys (ACS) imaging (Scoville et al. 2007ApJS..172...38S). With 583 single-orbit HST ACS F814W (I band; hereafter I814) observations, it is the largest contiguous HST imaging survey to date. The VLA-COSMOS large project (Schinnerer et al., 2007, Cat. J/ApJS/172/46) acquired deep, uniform 1.4GHz data over the entire COSMOS field using the A-array configuration of the Very Large Array (VLA). The XMM-Newton COSMOS survey (Hasinger et al., 2007, Cat. J/ApJS/172/29; Cappelluti et al., 2009, Cat. J/A+A/497/635) acquired deep X-ray data over the entire COSMOS HST ACS field. The S-COSMOS survey (Sanders et al., 2007ApJS..172...86S) is a Spitzer Legacy program which carried out a uniformly deep survey of the full COSMOS field in seven mid-IR bands (3.6, 4.5, 5.8, 8.0, 24, 70, and 160um). The Advanced Camera for Surveys General Catalog2 (ACS-GC) data (R.L. Griffith et al., 2012ApJS..200....9G) was constructed to study the evolution of galaxy morphologies over a wide range of look-back times. The ACS-GC uniformly analyzes the largest HST ACS imaging surveys (AEGIS, GEMS, GOODS-S, GOODS-N, and COSMOS) using the GALAPAGOS code. (3 data files).

  8. Chemostratigraphy and Fe Mineralogy of the Victoria Crater Duck Bay Section: Opportunity APXS and Moessbauer Results

    NASA Technical Reports Server (NTRS)

    Mittlefehldt, D. W.; Schroeder, C.; Gellert, R.; Klingelhoefer, G.; Jolliff, B. L.; Morris, R. V.

    2008-01-01

    Meridiani Planum is a vast plain of approximately horizontally bedded sedimentary rocks composed of mixed and reworked basaltic and evaporitic sands containing secondary, diagenetic minerals [e.g., 1-5]. Because bedding planes are subparallel to topography, investigation of contiguous stratigraphy requires examining exposures in impact craters. Early in the mission (sols 130-317), Opportunity was commanded to do detailed study of exposed outcrops in Endurance crater, including the contiguous Karatepe section at the point of ingress. Just over 1000 sols later and roughly 7 km to the south, the rover is being commanded to do a similar study of the Duck Bay section of Victoria crater. Here we report on the preliminary results from the Alpha Particle X-ray Spectrometer (APXS) and Moessbauer instruments.

  9. High temperature strain gages

    NASA Technical Reports Server (NTRS)

    Gregory, Otto J. (Inventor); You, Tao (Inventor)

    2011-01-01

    A ceramic strain gage based on reactively sputtered indium-tin-oxide (ITO) thin films is used to monitor the structural integrity of components employed in aerospace propulsion systems operating at temperatures in excess of 1500.degree. C. A scanning electron microscopy (SEM) of the thick ITO sensors reveals a partially sintered microstructure comprising a contiguous network of submicron ITO particles with well defined necks and isolated nanoporosity. Densification of the ITO particles was retarded during high temperature exposure with nitrogen thus stabilizing the nanoporosity. ITO strain sensors were prepared by reactive sputtering in various nitrogen/oxygen/argon partial pressures to incorporate more nitrogen into the films. Under these conditions, sintering and densification of the ITO particles containing these nitrogen rich grain boundaries was retarded and a contiguous network of nano-sized ITO particles was established.

  10. Method and structure for skewed block-cyclic distribution of lower-dimensional data arrays in higher-dimensional processor grids

    DOEpatents

    Chatterjee, Siddhartha [Yorktown Heights, NY; Gunnels, John A [Brewster, NY

    2011-11-08

    A method and structure of distributing elements of an array of data in a computer memory to a specific processor of a multi-dimensional mesh of parallel processors includes designating a distribution of elements of at least a portion of the array to be executed by specific processors in the multi-dimensional mesh of parallel processors. The pattern of the designating includes a cyclical repetitive pattern of the parallel processor mesh, as modified to have a skew in at least one dimension so that both a row of data in the array and a column of data in the array map to respective contiguous groupings of the processors such that a dimension of the contiguous groupings is greater than one.

  11. Enhancing clinical decision making: development of a contiguous definition and conceptual framework.

    PubMed

    Tiffen, Jennifer; Corbridge, Susan J; Slimmer, Lynda

    2014-01-01

    Clinical decision making is a term frequently used to describe the fundamental role of the nurse practitioner; however, other terms have been used interchangeably. The purpose of this article is to begin the process of developing a definition and framework of clinical decision making. The developed definition was "Clinical decision making is a contextual, continuous, and evolving process, where data are gathered, interpreted, and evaluated in order to select an evidence-based choice of action." A contiguous framework for clinical decision making specific for nurse practitioners is also proposed. Having a clear and unique understanding of clinical decision making will allow for consistent use of the term, which is relevant given the changing educational requirements for nurse practitioners and broadening scope of practice. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. Non-contiguous finished genome sequence of the opportunistic oral pathogen Prevotella multisaccharivorax type strain (PPPA20T)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pati, Amrita; Gronow, Sabine; Lu, Megan

    2011-01-01

    Prevotella multisaccharivorax Sakamoto et al. 2005 is a species of the large genus Prevotella, which belongs to the family Prevotellaceae. The species is of medical interest because its members are able to cause diseases in the human oral cavity such as periodontitis, root caries and others. Although 77 Prevotella genomes have already been sequenced or are targeted for sequencing, this is only the second completed genome sequence of a type strain of a species within the genus Prevotella to be published. The 3,388,644 bp long genome is assembled in three non-contiguous contigs, harbors 2,876 protein-coding and 75 RNA genes andmore » is a part of the Genomic Encyclopedia of Bacteria and Archaea project.« less

  13. Communicating NASA's Knowledge: A Report of the Communicate Knowledge Process Team

    NASA Technical Reports Server (NTRS)

    1998-01-01

    NASA has a unique charter in the Space Act of 1958 to 'provide for the widest practicable and appropriate dissemination of information concerning its activities and the results thereof.' As NASA approaches the new millennium, Government legislation and regulations, budgetary reductions that have necessitated downsizing the workforce, an emphasis on measurable results from Government agencies, and technological communications breakthroughs have provided the impetus for NASA to reexamine the way it communicates the knowledge that it generates. NASA has been challenged to manage knowledge as a resource that we owe to the American people.

  14. NSSDC and WDC-A-R/S document availability and distribution services

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Documents available from the National Space Science Data Center (NSSDC) and the World Data Center A for Rockets Satellites are described. The availability, costs, ordering procedures for documents presently available, and the procedures for obtaining future documents are given. NSSDC, established by NASA to further the widest practicable use of reduced data obtained from space science investigations and to provide investigators with an active repository for such data, is responsible for the active collection, organization, storage, announcement, retrieval, dissemination, and exchange of data received from satellite experiments. Information on sounding rocket investigations is also collected.

  15. Hepatitis Virus Capsid Polymorphs Respond Differently to Changes in Encapsulated Cargo Size

    PubMed Central

    He, Li; Porterfield, J. Zachary; van der Schoot, Paul; Zlotnick, Adam; Dragnea, Bogdan

    2017-01-01

    A templated assembly approach for Hepatitis B virus-like particles was employed to determine how the T = 3 and T = 4 polymorphs of the Hepatitis B virus (HBV) icosahedral cores respond to a systematic, gradual change in the encapsulated cargo size. It was found that assembly into complete virus-like particles occurs cooperatively around a variety of core diameters, albeit the degree of cooperativity varies. Among these virus-like particles, it was found that those of an outer diameter similar to T = 4 are able to accommodate the widest range of cargo sizes. PMID:24010404

  16. Weaving a Webb story: Communicating Science for JWST

    NASA Astrophysics Data System (ADS)

    Lockwood, Alexandra

    2018-01-01

    NASA’s next great observatory is an impressive and complex mission with many tales to tell. Science is a collection of stories and Webb will be a storytelling machine. How are we preparing to share the scientific news to come from this amazing telescope? From news releases to multimedia content to a vast online presence, the stories of the James Webb Space Telescope will require crafting in order to impact the widest audience. We discuss the art of storytelling based on messaging, goals, mediums, and audience, and how you can apply the same principles to communicating your own research.

  17. Archaeological Investigations at Sites 45-OK-250 and 45-OK-4, Chief Joseph Dam Project, Washington.

    DTIC Science & Technology

    1984-01-01

    level behind Chief Joseph Dam. Systematic random sampling using I x I x ’ - 0.1-m collection units in 1 x 1, 1 x 2, or 2 x 2 m cel Is disclosed...ft to the operating pool . level behind Chief Joseph Dam. Systematic random sampling using 1 x 1 x 0.1-i collection units In 1 x 1, 1 x 2, or 2 x 2 m...contingencies under which data were collected , describe data collection and analysis, and organize and summarize data In a torm useful to the widest

  18. Heat Capacity Mapping Mission (HCMM) Notification Efforts

    NASA Technical Reports Server (NTRS)

    1980-01-01

    To encourage wide use of the Heat Capacity Mapping Mission (HCMM) data, especially among the scientific community, special notifications were prepared to inform them about the data's availability, its form, and the procedures for obtaining them. To achieve the widest distribution to the primary audiences of interest, mailings were made to scientists associated with the OSTA Resource Observation Division programs and to scientific and professional societies and journals. Accompanying the notifications to the societies and journals were samples of the HCMM imagery and a description of the image's predominant characteristics. A follow-up survey was completed to determine the effectiveness of the HCMM notifications.

  19. Collection overview: ten years of wonderful open access science.

    PubMed

    Roberts, Roland G; Alfred, Jane

    2013-10-01

    To mark our tenth Anniversary at PLOS Biology, we are launching a special, celebratory Tenth Anniversary PLOS Biology Collection which showcases 10 specially selected PLOS Biology research articles drawn from a decade of publishing excellent science. It also features newly commissioned articles, including thought-provoking pieces on the Open Access movement (past and present), on article-level metrics, and on the history of the Public Library of Science. Each research article highlighted in the collection is also accompanied by a PLOS Biologue blog post to extend the impact of these remarkable studies to the widest possible audience.

  20. A Volcanic Fissure

    NASA Image and Video Library

    2017-04-26

    Although Mars is known for having the largest volcano in our solar system, Olympus Mons, we also find small-scale volcanic features on its surface, as shown in this image from HiRISE onboard NASA's Mars Reconnaissance Orbiter (MRO). This fissure, less than 500 meters across at its widest point, lies in the Tharsis region and is believed to be a vent from which lava flowed in ancient eruptions. The total volume of lava released from this fissure is much less than what would erupt from nearby volcanoes, but the mark left on the landscape is dramatic nonetheless. https://photojournal.jpl.nasa.gov/catalog/PIA21601

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