A service-based BLAST command tool supported by cloud infrastructures.

PubMed

Carrión, Abel; Blanquer, Ignacio; Hernández, Vicente

2012-01-01

Notwithstanding the benefits of distributed-computing infrastructures for empowering bioinformatics analysis tools with the needed computing and storage capability, the actual use of these infrastructures is still low. Learning curves and deployment difficulties have reduced the impact on the wide research community. This article presents a porting strategy of BLAST based on a multiplatform client and a service that provides the same interface as sequential BLAST, thus reducing learning curve and with minimal impact on their integration on existing workflows. The porting has been done using the execution and data access components from the EC project Venus-C and the Windows Azure infrastructure provided in this project. The results obtained demonstrate a low overhead on the global execution framework and reasonable speed-up and cost-efficiency with respect to a sequential version.

Quantitative Analysis of Immunohistochemistry in Melanoma Tumors

PubMed Central

Lilyquist, Jenna; White, Kirsten Anne Meyer; Lee, Rebecca J.; Philips, Genevieve K.; Hughes, Christopher R.; Torres, Salina M.

2017-01-01

Abstract Identification of positive staining is often qualitative and subjective. This is particularly troublesome in pigmented melanoma lesions, because melanin is difficult to distinguish from the brown stain resulting from immunohistochemistry (IHC) using horse radish peroxidase developed with 3,3′-Diaminobenzidine (HRP-DAB). We sought to identify and quantify positive staining, particularly in melanoma lesions. We visualized G-protein coupled estrogen receptor (GPER) expression developed with HRP-DAB and counterstained with Azure B (stains melanin) in melanoma tissue sections (n = 3). Matched sections (n = 3), along with 22 unmatched sections, were stained only with Azure B as a control. Breast tissue (n = 1) was used as a positive HRP-DAB control. Images of the stained tissues were generated using a Nuance Spectral Imaging Camera. Analysis of the images was performed using the Nuance Spectral Imaging software and SlideBook. Data was analyzed using a Kruskal–Wallis one way analysis of variance (ANOVA). We showed that a pigmented melanoma tissue doubly stained with anti-GPER HRP-DAB and Azure B can be unmixed using spectra derived from a matched, Azure B-only section, and an anti-GPER HRP-DAB control. We unmixed each of the melanoma lesions using each of the Azure B spectra, evaluated the mean intensity of positive staining, and examined the distribution of the mean intensities (P = .73; Kruskal–Wallis). These results suggest that this method does not require a matched Azure B-only stained control tissue for every melanoma lesion, allowing precious tissues to be conserved for other studies. Importantly, this quantification method reduces the subjectivity of protein expression analysis, and provides a valuable tool for accurate evaluation, particularly for pigmented tissues. PMID:28403073

Cost Optimal Elastic Auto-Scaling in Cloud Infrastructure

NASA Astrophysics Data System (ADS)

Mukhopadhyay, S.; Sidhanta, S.; Ganguly, S.; Nemani, R. R.

2014-12-01

Today, elastic scaling is critical part of leveraging cloud. Elastic scaling refers to adding resources only when it is needed and deleting resources when not in use. Elastic scaling ensures compute/server resources are not over provisioned. Today, Amazon and Windows Azure are the only two platform provider that allow auto-scaling of cloud resources where servers are automatically added and deleted. However, these solution falls short of following key features: A) Requires explicit policy definition such server load and therefore lacks any predictive intelligence to make optimal decision; B) Does not decide on the right size of resource and thereby does not result in cost optimal resource pool. In a typical cloud deployment model, we consider two types of application scenario: A. Batch processing jobs → Hadoop/Big Data case B. Transactional applications → Any application that process continuous transactions (Requests/response) In reference of classical queuing model, we are trying to model a scenario where servers have a price and capacity (size) and system can add delete servers to maintain a certain queue length. Classical queueing models applies to scenario where number of servers are constant. So we cannot apply stationary system analysis in this case. We investigate the following questions 1. Can we define Job queue and use the metric to define such a queue to predict the resource requirement in a quasi-stationary way? Can we map that into an optimal sizing problem? 2. Do we need to get into a level of load (CPU/Data) on server level to characterize the size requirement? How do we learn that based on Job type?

INNOVATIVE TECHNOLOGY VERIFICATION REPORT "FIELD MEASUREMENT TECHNOLOGIES FOR TOTAL PETROLEUM HYDROCARBONS IN SOIL" CHEMETRICS, INC., AND AZUR ENVIRONMENTAL LTD REMEDIAID TOTAL PETROLEUM HYDROCARBON STARTER KIT

EPA Science Inventory

The RemediAidTm Total Petroleum Hydrocarbon Starter Kit (RemediAidTm kit) developed by CHEMetries, Inc. (CHEMetrics), and AZUR Environmental Ltd was demonstrated under the U.S. Environmental Protection Agency Superfund Innovative Technology Evaluation Program in June 2000 at the ...

NASA Glenn Steady-State Heat Pipe Code GLENHP: Compilation for 64- and 32-Bit Windows Platforms

NASA Technical Reports Server (NTRS)

Tower, Leonard K.; Geng, Steven M.

2016-01-01

A new version of the NASA Glenn Steady State Heat Pipe Code, designated "GLENHP," is introduced here. This represents an update to the disk operating system (DOS) version LERCHP reported in NASA/TM-2000-209807. The new code operates on 32- and 64-bit Windows-based platforms from within the 32-bit command prompt window. An additional evaporator boundary condition and other features are provided.

Cross-Platform Development Techniques for Mobile Devices

DTIC Science & Technology

2013-09-01

many other platforms including Windows, Blackberry , and Symbian. Each of these platforms has their own distinct architecture and programming language...sales of iPhones and the increasing use of Android-based devices have forced less successful competitors such as Microsoft, Blackberry , and Symbian... Blackberry and Windows Phone are planned [12] in this tool’s attempt to reuse code with a unified JavaScript API while at the same time supporting unique

Cross platform development using Delphi and Kylix

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDonald, J.L.; Nishimura, H.; Timossi, C.

2002-10-08

A cross platform component for EPICS Simple Channel Access (SCA) has been developed for the use with Delphi on Windows and Kylix on Linux. An EPICS controls GUI application developed on Windows runs on Linux by simply rebuilding it, and vice versa. This paper describes the technical details of the component.

An interactive web-based system using cloud for large-scale visual analytics

NASA Astrophysics Data System (ADS)

Kaseb, Ahmed S.; Berry, Everett; Rozolis, Erik; McNulty, Kyle; Bontrager, Seth; Koh, Youngsol; Lu, Yung-Hsiang; Delp, Edward J.

2015-03-01

Network cameras have been growing rapidly in recent years. Thousands of public network cameras provide tremendous amount of visual information about the environment. There is a need to analyze this valuable information for a better understanding of the world around us. This paper presents an interactive web-based system that enables users to execute image analysis and computer vision techniques on a large scale to analyze the data from more than 65,000 worldwide cameras. This paper focuses on how to use both the system's website and Application Programming Interface (API). Given a computer program that analyzes a single frame, the user needs to make only slight changes to the existing program and choose the cameras to analyze. The system handles the heterogeneity of the geographically distributed cameras, e.g. different brands, resolutions. The system allocates and manages Amazon EC2 and Windows Azure cloud resources to meet the analysis requirements.

Increasing information accessibility for patients in obstetrics-gynecology domain.

PubMed

Crişan-Vida, Mihaela; Stoicu-Tivadar, Lăcrămioara

2014-01-01

It is important for the patient to have access to personal medical information in order to manage information for increased quality of medical care and life. The paper presents a module added to an Obstetrics-Gynaecology Department information system (OGD IS) supporting patient empowerment. The patient is accessing the system easily using laptops or mobile devices. The application accessed by the patient is web-based, implemented in Visual Studio. NET, using ASP.NET pages and C# language, and the application is published in the Windows Azure cloud. The solution is user friendly using familiar devices and is ubiquitous using the cloud solution. A module for translating medical terms in colloquial ones is integrated in the system. For certain situations the patient will get information related to life style influencing health status as how and what to eat or what type of exercise it is recommended.

VA's Integrated Imaging System on three platforms.

PubMed

Dayhoff, R E; Maloney, D L; Majurski, W J

1992-01-01

The DHCP Integrated Imaging System provides users with integrated patient data including text, image and graphics data. This system has been transferred from its original two screen DOS-based MUMPS platform to an X window workstation and a Microsoft Windows-based workstation. There are differences between these various platforms that impact on software design and on software development strategy. Data structures and conventions were used to isolate hardware, operating system, imaging software, and user-interface differences between platforms in the implementation of functionality for text and image display and interaction. The use of an object-oriented approach greatly increased system portability.

VA's Integrated Imaging System on three platforms.

PubMed Central

Dayhoff, R. E.; Maloney, D. L.; Majurski, W. J.

1992-01-01

The DHCP Integrated Imaging System provides users with integrated patient data including text, image and graphics data. This system has been transferred from its original two screen DOS-based MUMPS platform to an X window workstation and a Microsoft Windows-based workstation. There are differences between these various platforms that impact on software design and on software development strategy. Data structures and conventions were used to isolate hardware, operating system, imaging software, and user-interface differences between platforms in the implementation of functionality for text and image display and interaction. The use of an object-oriented approach greatly increased system portability. PMID:1482983

DOE Office of Scientific and Technical Information (OSTI.GOV)

P-Mart was designed specifically to allow cancer researchers to perform robust statistical processing of publicly available cancer proteomic datasets. To date an online statistical processing suite for proteomics does not exist. The P-Mart software is designed to allow statistical programmers to utilize these algorithms through packages in the R programming language as well as offering a web-based interface using the Azure cloud technology. The Azure cloud technology also allows the release of the software via Docker containers.

Architecture Design of Healthcare Software-as-a-Service Platform for Cloud-Based Clinical Decision Support Service.

PubMed

Oh, Sungyoung; Cha, Jieun; Ji, Myungkyu; Kang, Hyekyung; Kim, Seok; Heo, Eunyoung; Han, Jong Soo; Kang, Hyunggoo; Chae, Hoseok; Hwang, Hee; Yoo, Sooyoung

2015-04-01

To design a cloud computing-based Healthcare Software-as-a-Service (SaaS) Platform (HSP) for delivering healthcare information services with low cost, high clinical value, and high usability. We analyzed the architecture requirements of an HSP, including the interface, business services, cloud SaaS, quality attributes, privacy and security, and multi-lingual capacity. For cloud-based SaaS services, we focused on Clinical Decision Service (CDS) content services, basic functional services, and mobile services. Microsoft's Azure cloud computing for Infrastructure-as-a-Service (IaaS) and Platform-as-a-Service (PaaS) was used. The functional and software views of an HSP were designed in a layered architecture. External systems can be interfaced with the HSP using SOAP and REST/JSON. The multi-tenancy model of the HSP was designed as a shared database, with a separate schema for each tenant through a single application, although healthcare data can be physically located on a cloud or in a hospital, depending on regulations. The CDS services were categorized into rule-based services for medications, alert registration services, and knowledge services. We expect that cloud-based HSPs will allow small and mid-sized hospitals, in addition to large-sized hospitals, to adopt information infrastructures and health information technology with low system operation and maintenance costs.

T2L2 on JASON-2: First Evaluation of the Flying Model

DTIC Science & Technology

2007-01-01

Para, J.-M. Torre R&D Metrology CNRS/GEMINI Observatoire de la Côte d’Azur Caussol, France E-mail: philippe.guillemot@cnes.fr Abstract...Laser Link” experiment T2L2 [1], under development at OCA (Observatoire de la Côte d’Azur) and CNES (Centre National d’Etudes Spatiales), France, will be...Experimental Astronomy, 7, 191-207. [2] P. Fridelance and C. Veillet, 1995, “Operation and data analysis in the LASSO experiment,” Metrologia

Removable Window System for Space Vehicles

NASA Technical Reports Server (NTRS)

Grady, James P. (Inventor)

2015-01-01

A window system for a platform comprising a window pane, a retention frame, and a biasing system. The window pane may be configured to contact a sealing system. The retention frame may be configured to contact the sealing system and hold the window pane against the support frame. The biasing system may be configured to bias the retention frame toward the support frame while the support frame and the retention frame are in a configuration that holds the window pane. Removal of the biasing system may cause the retention frame and the window pane to be removable.

A CASE STUDY USING THE EPA'S WATER QUALITY MODELING SYSTEM, THE WINDOWS INTERFACE FOR SIMULATING PLUMES (WISP)

EPA Science Inventory

Wisp, the Windows Interface for Simulating Plumes, is designed to be an easy-to-use windows platform program for aquatic modeling. Wisp inherits many of its capabilities from its predecessor, the DOS-based PLUMES (Baumgartner, Frick, Roberts, 1994). These capabilities have been ...

VISUAL PLUMES CONCEPTS TO POTENTIALLY ADAPT OR ADOPT IN MODELING PLATFORMS SUCH AS VISJET

EPA Science Inventory

Windows-based programs share many familiar features and components. For example, file dialogue windows are familiar to most Windows-based personal computer users. Such program elements are desirable because the user is already familiar with how they function, obviating the need f...

Software structure for Vega/Chara instrument

NASA Astrophysics Data System (ADS)

Clausse, J.-M.

2008-07-01

VEGA (Visible spEctroGraph and polArimeter) is one of the focal instruments of the CHARA array at Mount Wilson near Los Angeles. Its control system is based on techniques developed on the GI2T interferometer (Grand Interferometre a 2 Telescopes) and on the SIRIUS fibered hyper telescope testbed at OCA (Observatoire de la Cote d'Azur). This article describes the software and electronics architecture of the instrument. It is based on local network architecture and uses also Virtual Private Network connections. The server part is based on Windows XP (VC++). The control software is on Linux (C, GTK). For the control of the science detector and the fringe tracking systems, distributed API use real-time techniques. The control software gathers all the necessary informations of the instrument. It allows an automatic management of the instrument by using an original task scheduler. This architecture intends to drive the instrument from remote sites, such as our institute in South of France.

Efficient Comparison between Windows and Linux Platform Applicable in a Virtual Architectural Walkthrough Application

NASA Astrophysics Data System (ADS)

Thubaasini, P.; Rusnida, R.; Rohani, S. M.

This paper describes Linux, an open source platform used to develop and run a virtual architectural walkthrough application. It proposes some qualitative reflections and observations on the nature of Linux in the concept of Virtual Reality (VR) and on the most popular and important claims associated with the open source approach. The ultimate goal of this paper is to measure and evaluate the performance of Linux used to build the virtual architectural walkthrough and develop a proof of concept based on the result obtain through this project. Besides that, this study reveals the benefits of using Linux in the field of virtual reality and reflects a basic comparison and evaluation between Windows and Linux base operating system. Windows platform is use as a baseline to evaluate the performance of Linux. The performance of Linux is measured based on three main criteria which is frame rate, image quality and also mouse motion.

Quirks of dye nomenclature. 8. Methylene blue, azure and violet.

PubMed

Cooksey, C J

2017-01-01

Methylene blue was synthesized in 1877 and soon found application in medicine, staining for microscopy and as an industrial dye and pigment. An enormous literature has accumulated since its introduction. Early on, it was known that methylene blue could be degraded easily by demethylation; consequently, the purity of commercial samples often was low. Therefore, demethylation products, such as azures and methylene violet, also are considered here. The names and identity of the components, their varying modes of manufacture, analytical methods and their contribution to biological staining are discussed.

Architecture Design of Healthcare Software-as-a-Service Platform for Cloud-Based Clinical Decision Support Service

PubMed Central

Oh, Sungyoung; Cha, Jieun; Ji, Myungkyu; Kang, Hyekyung; Kim, Seok; Heo, Eunyoung; Han, Jong Soo; Kang, Hyunggoo; Chae, Hoseok; Hwang, Hee

2015-01-01

Objectives To design a cloud computing-based Healthcare Software-as-a-Service (SaaS) Platform (HSP) for delivering healthcare information services with low cost, high clinical value, and high usability. Methods We analyzed the architecture requirements of an HSP, including the interface, business services, cloud SaaS, quality attributes, privacy and security, and multi-lingual capacity. For cloud-based SaaS services, we focused on Clinical Decision Service (CDS) content services, basic functional services, and mobile services. Microsoft's Azure cloud computing for Infrastructure-as-a-Service (IaaS) and Platform-as-a-Service (PaaS) was used. Results The functional and software views of an HSP were designed in a layered architecture. External systems can be interfaced with the HSP using SOAP and REST/JSON. The multi-tenancy model of the HSP was designed as a shared database, with a separate schema for each tenant through a single application, although healthcare data can be physically located on a cloud or in a hospital, depending on regulations. The CDS services were categorized into rule-based services for medications, alert registration services, and knowledge services. Conclusions We expect that cloud-based HSPs will allow small and mid-sized hospitals, in addition to large-sized hospitals, to adopt information infrastructures and health information technology with low system operation and maintenance costs. PMID:25995962

Scalable, Secure Analysis of Social Sciences Data on the Azure Platform

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simmhan, Yogesh; Deng, Litao; Kumbhare, Alok

2012-05-07

Human activity and interaction data is beginning to be collected at population scales through the pervasiveness of social media and willingness of people to volunteer information. This can allow social science researchers to understand and model human behavior with better accuracy and prediction power. Political and social scientists are starting to correlate such large scale social media datasets with events that impact society as evidence abound of the virtual and physical public spaces intersecting and influencing each other [1,2]. Managers of Cyber Physical Systems such as Smart Power Grid utilities are investigating the impact of consumer behavior on power consumption,more » and the possibility of influencing the usage profile [3]. Data collection is also made easier through technology such as mobile apps, social media sites and search engines that directly collect data, and sensors such smart meters and room occupancy sensors that indirectly measure human activity. These technology platforms also provide a convenient framework for “human sensors” to record and broadcast data for behavioral studies, as a form of crowd sourced citizen science. This has the added advantage of engaging the broader public in STEM activities and help influence public policy.« less

Classes Azur Astro Espace International Hands-on Space Experience

NASA Astrophysics Data System (ADS)

Jung, P.

2002-01-01

Created in 1994 in the wake of the closure of the Space Camp of Patrick Baudry in Cannes, Classes Azur Astro Espace (AAE) provide a world's unique combination of space and astronomy courses, as given by active and retired professionals of two of the best space and astronomical facilities extant: Alcatel Space in Cannes and Observatoire de la Côte d'Azur (OCA) in Nice, Grasse and Caussols. Fifteen space modules, of 30 to 60 minutes each, have been established, giving simple and clear explanations on launchers, satellites, their applications, their development, together with an historical background. Basic experiments are included, such as an unique small catapult to explain gravity, or more classical water rockets. The basic AAE sojourn extends over 3 days: one day for space (including a visit of Alcatel Space, the biggest satellite manufacturer outside the US and Russia), one day for astronomy (including a visit of the biggest observatory in Europe) and one day à-la-carte (Côte d'Azur offers much, such as the Oceanographic Museum in Monaco). More and more groups are adding a fourth day, with a visit to the nice old village of Perinaldo in Italy, where famous astronomer Cassini was born. Lycée de Cachan, near Paris, even takes 12-day sojourns every year. The public has been extremely wide, from age 5 to 70, from students to enthusiasts. Coming initially all over from France, participants now include since 2001 German and Italian pupils and teachers. In 2001 also, ESA came in the shape of a Space Camp. ISU's Master of Space Studies participates to a shortened version of AAE every even-year. Up to the end of 2001, 62 classes with 2,025 participants from 20 countries had thus come to enjoy space education on Côte d'Azur. Such success is due in no small part to the very attractive price and flexibility of these activities, notably thanks to the support of ESA, CNES, Rectorat d'Académie de Nice, Conseil Général des Alpes-Maritimes, Ville de Cannes, AAAF, TDF, Alcatel Space and OCA.

Millisecond timing on PCs and Macs.

PubMed

MacInnes, W J; Taylor, T L

2001-05-01

A real-time, object-oriented solution for displaying stimuli on Windows 95/98, MacOS and Linux platforms is presented. The program, written in C++, utilizes a special-purpose window class (GLWindow), OpenGL, and 32-bit graphics acceleration; it avoids display timing uncertainty by substituting the new window class for the default window code for each system. We report the outcome of tests for real-time capability across PC and Mac platforms running a variety of operating systems. The test program, which can be used as a shell for programming real-time experiments and testing specific processors, is available at http://www.cs.dal.ca/~macinnwj. We propose to provide researchers with a sense of the usefulness of our program, highlight the ability of many multitasking environments to achieve real time, as well as caution users about systems that may not achieve real time, even under optimal conditions.

Non-enzymatic detection of glucose using poly(azure A)-nickel modified glassy carbon electrode.

PubMed

Liu, Tong; Luo, Yiqun; Zhu, Jiaming; Kong, Liyan; Wang, Wen; Tan, Liang

2016-08-15

A simple, sensitive and selective non-enzymatic glucose sensor was constructed in this paper. The poly(azure A)-nickel modified glassy carbon electrode was successfully fabricated by the electropolymerization of azure A and the adsorption of Ni(2+). The Ni modified electrode, which was characterized by scanning electron microscope, cyclic voltammetry, electrochemical impedance spectra and X-ray photoelectron spectroscopy measurements, respectively, displayed well-defined current responses of the Ni(III)/Ni(II) couple and showed a good activity for electrocatalytic oxidation of glucose in alkaline medium. Under the optimized conditions, the developed sensor exhibited a broad linear calibration range of 5 μM-12mM for quantification of glucose and a low detection limit of 0.64μM (3σ). The excellent analytical performance including simple structure, fast response time, good anti-interference ability, satisfying stability and reliable reproducibility were also found from the proposed amperometric sensor. The results were satisfactory for the determination of glucose in human serum samples as comparison to those from a local hospital. Copyright © 2016 Elsevier B.V. All rights reserved.

Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine.

PubMed

Pakavathkumar, Prateep; Sharma, Gyanesh; Kaushal, Vikas; Foveau, Bénédicte; LeBlanc, Andrea C

2015-09-24

Methylene blue, currently in phase 3 clinical trials against Alzheimer Disease, disaggregates the Tau protein of neurofibrillary tangles by oxidizing specific cysteine residues. Here, we investigated if methylene blue can inhibit caspases via the oxidation of their active site cysteine. Methylene blue, and derivatives, azure A and azure B competitively inhibited recombinant Caspase-6 (Casp6), and inhibited Casp6 activity in transfected human colon carcinoma cells and in serum-deprived primary human neuron cultures. Methylene blue also inhibited recombinant Casp1 and Casp3. Furthermore, methylene blue inhibited Casp3 activity in an acute mouse model of liver toxicity. Mass spectrometry confirmed methylene blue and azure B oxidation of the catalytic Cys163 cysteine of Casp6. Together, these results show a novel inhibitory mechanism of caspases via sulfenation of the active site cysteine. These results indicate that methylene blue or its derivatives could (1) have an additional effect against Alzheimer Disease by inhibiting brain caspase activity, (2) be used as a drug to prevent caspase activation in other conditions, and (3) predispose chronically treated individuals to cancer via the inhibition of caspases.

Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine

PubMed Central

Pakavathkumar, Prateep; Sharma, Gyanesh; Kaushal, Vikas; Foveau, Bénédicte; LeBlanc, Andrea C.

2015-01-01

Methylene blue, currently in phase 3 clinical trials against Alzheimer Disease, disaggregates the Tau protein of neurofibrillary tangles by oxidizing specific cysteine residues. Here, we investigated if methylene blue can inhibit caspases via the oxidation of their active site cysteine. Methylene blue, and derivatives, azure A and azure B competitively inhibited recombinant Caspase-6 (Casp6), and inhibited Casp6 activity in transfected human colon carcinoma cells and in serum-deprived primary human neuron cultures. Methylene blue also inhibited recombinant Casp1 and Casp3. Furthermore, methylene blue inhibited Casp3 activity in an acute mouse model of liver toxicity. Mass spectrometry confirmed methylene blue and azure B oxidation of the catalytic Cys163 cysteine of Casp6. Together, these results show a novel inhibitory mechanism of caspases via sulfenation of the active site cysteine. These results indicate that methylene blue or its derivatives could (1) have an additional effect against Alzheimer Disease by inhibiting brain caspase activity, (2) be used as a drug to prevent caspase activation in other conditions, and (3) predispose chronically treated individuals to cancer via the inhibition of caspases. PMID:26400108

IoT-based flood embankments monitoring system

NASA Astrophysics Data System (ADS)

Michta, E.; Szulim, R.; Sojka-Piotrowska, A.; Piotrowski, K.

2017-08-01

In the paper a concept of flood embankments monitoring system based on using Internet of Things approach and Cloud Computing technologies will be presented. The proposed system consists of sensors, IoT nodes, Gateways and Cloud based services. Nodes communicates with the sensors measuring certain physical parameters describing the state of the embankments and communicates with the Gateways. Gateways are specialized active devices responsible for direct communication with the nodes, collecting sensor data, preprocess the data, applying local rules and communicate with the Cloud Services using communication API delivered by cloud services providers. Architecture of all of the system components will be proposed consisting IoT devices functionalities description, their communication model, software modules and services bases on using a public cloud computing platform like Microsoft Azure will be proposed. The most important aspects of maintaining the communication in a secure way will be shown.

Scientific Data Storage for Cloud Computing

NASA Astrophysics Data System (ADS)

Readey, J.

2014-12-01

Traditionally data storage used for geophysical software systems has centered on file-based systems and libraries such as NetCDF and HDF5. In contrast cloud based infrastructure providers such as Amazon AWS, Microsoft Azure, and the Google Cloud Platform generally provide storage technologies based on an object based storage service (for large binary objects) complemented by a database service (for small objects that can be represented as key-value pairs). These systems have been shown to be highly scalable, reliable, and cost effective. We will discuss a proposed system that leverages these cloud-based storage technologies to provide an API-compatible library for traditional NetCDF and HDF5 applications. This system will enable cloud storage suitable for geophysical applications that can scale up to petabytes of data and thousands of users. We'll also cover other advantages of this system such as enhanced metadata search.

Window Observational Research Facility (WORF)

NASA Technical Reports Server (NTRS)

Pelfrey, Joseph; Sledd, Annette

2007-01-01

This viewgraph document concerns the Window Observational Research Facility (WORF) Rack, a unique facility designed for use with the US Lab Destiny Module window. WORF will provide valuable resources for Earth Science payloads along with serving the purpose of protecting the lab window. The facility can be used for remote sensing instrumentation test and validation in a shirt sleeve environment. WORF will also provide a training platform for crewmembers to do orbital observations of other planetary bodies. WORF payloads will be able to conduct terrestrial studies utilizing the data collected from utilizing WORF and the lab window.

Design and implementation of laser target simulator in hardware-in-the-loop simulation system based on LabWindows/CVI and RTX

NASA Astrophysics Data System (ADS)

Tong, Qiujie; Wang, Qianqian; Li, Xiaoyang; Shan, Bin; Cui, Xuntai; Li, Chenyu; Peng, Zhong

2016-11-01

In order to satisfy the requirements of the real-time and generality, a laser target simulator in semi-physical simulation system based on RTX+LabWindows/CVI platform is proposed in this paper. Compared with the upper-lower computers simulation platform architecture used in the most of the real-time system now, this system has better maintainability and portability. This system runs on the Windows platform, using Windows RTX real-time extension subsystem to ensure the real-time performance of the system combining with the reflective memory network to complete some real-time tasks such as calculating the simulation model, transmitting the simulation data, and keeping real-time communication. The real-time tasks of simulation system run under the RTSS process. At the same time, we use the LabWindows/CVI to compile a graphical interface, and complete some non-real-time tasks in the process of simulation such as man-machine interaction, display and storage of the simulation data, which run under the Win32 process. Through the design of RTX shared memory and task scheduling algorithm, the data interaction between the real-time tasks process of RTSS and non-real-time tasks process of Win32 is completed. The experimental results show that this system has the strongly real-time performance, highly stability, and highly simulation accuracy. At the same time, it also has the good performance of human-computer interaction.

Town Lake bottom sediments : a chronicle of water quality changes in Austin, Texas, 1960-98

USGS Publications Warehouse

Van Metre, Peter C.; Mahler, B.J.

1999-01-01

Town Lake, the last in the chain of Highland Lakes on the Colorado River, runs through the center of Austin, Texas. On any given day, grebes and coots dot the water, rowers skim alongside, and the sparkle of the sun on the water can be admired from the adjacent hike and bike path and from the windows of nearby office buildings. During the summer months, crowds gather along the shores of Town Lake to watch as many as 1 million Mexican Free-Tail bats emerge from under the Congress Avenue bridge. But below the lazily moving azure water lies a bed of sediment about 1 meter (m) thick?sediment that has been deposited gradually since the reservoir was formed in 1959 and that has been recording changes in water quality since that time. What can this sediment tell us about the history of water quality in the Colorado River? And what does it say about the effects of the rapid urbanization of Austin and the future health of our environment?

Automatic energy expenditure measurement for health science.

PubMed

Catal, Cagatay; Akbulut, Akhan

2018-04-01

It is crucial to predict the human energy expenditure in any sports activity and health science application accurately to investigate the impact of the activity. However, measurement of the real energy expenditure is not a trivial task and involves complex steps. The objective of this work is to improve the performance of existing estimation models of energy expenditure by using machine learning algorithms and several data from different sensors and provide this estimation service in a cloud-based platform. In this study, we used input data such as breathe rate, and hearth rate from three sensors. Inputs are received from a web form and sent to the web service which applies a regression model on Azure cloud platform. During the experiments, we assessed several machine learning models based on regression methods. Our experimental results showed that our novel model which applies Boosted Decision Tree Regression in conjunction with the median aggregation technique provides the best result among other five regression algorithms. This cloud-based energy expenditure system which uses a web service showed that cloud computing technology is a great opportunity to develop estimation systems and the new model which applies Boosted Decision Tree Regression with the median aggregation provides remarkable results. Copyright © 2018 Elsevier B.V. All rights reserved.

Stewardship and management challenges within a cloud-based open data ecosystem (Invited Paper 211863)

NASA Astrophysics Data System (ADS)

Kearns, E. J.

2017-12-01

NOAA's Big Data Project is conducting an experiment in the collaborative distribution of open government data to non-governmental cloud-based systems. Through Cooperative Research and Development Agreements signed in 2015 between NOAA and Amazon Web Services, Google Cloud Platform, IBM, Microsoft Azure, and the Open Commons Consortium, NOAA is distributing open government data to a wide community of potential users. There are a number of significant advantages related to the use of open data on commercial cloud platforms, but through this experiment NOAA is also discovering significant challenges for those stewarding and maintaining NOAA's data resources in support of users in the wider open data ecosystem. Among the challenges that will be discussed are: the need to provide effective interpretation of the data content to enable their use by data scientists from other expert communities; effective maintenance of Collaborators' open data stores through coordinated publication of new data and new versions of older data; the provenance and verification of open data as authentic NOAA-sourced data across multiple management boundaries and analytical tools; and keeping pace with the accelerating expectations of users with regard to improved quality control, data latency, availability, and discoverability. Suggested strategies to address these challenges will also be described.

Wind shear over the Nice Côte d'Azur airport: case studies

NASA Astrophysics Data System (ADS)

Boilley, A.; Mahfouf, J.-F.

2013-09-01

The Nice Côte d'Azur international airport is subject to horizontal low-level wind shears. Detecting and predicting these hazards is a major concern for aircraft security. A measurement campaign took place over the Nice airport in 2009 including 4 anemometers, 1 wind lidar and 1 wind profiler. Two wind shear events were observed during this measurement campaign. Numerical simulations were carried out with Meso-NH in a configuration compatible with near-real time applications to determine the ability of the numerical model to predict these events and to study the meteorological situations generating an horizontal wind shear. A comparison between numerical simulation and the observation dataset is conducted in this paper.

Wind shear over the Nice Côte d'Azur airport: case studies

NASA Astrophysics Data System (ADS)

Boilley, A.; Mahfouf, J.-F.

2013-04-01

The Nice Côte d'Azur international airport is subject to horizontal low-level wind shears. Detecting and predicting these hazards is a major concern for aircraft security. A measurement campaign took place over the Nice airport in 2009 including 4 anemometers, 1 wind lidar and 1 wind profiler. Two wind shear events were observed during this measurement campaign. Numerical simulations were carried out with Meso-NH in a configuration compatible with near-real time applications to determine the ability of the numerical model to predict these events and to study the meteorological situations generating a horizontal wind shear. A comparison between numerical simulation and the observation dataset is conducted in this paper.

Measures and Trends U.S. and U.S.S.R. Strategic Force Effectiveness. (Sanitized)

DTIC Science & Technology

1978-07-01

is limited by the uncer- tainties and inaccracies present in the data which are used to develop the moasure. In the main body of the text the...alplizan1e to the prvostwu noas;urO5 arc ar;ici~to tn; ~~z~ ’i.r 2ctwo mt- azurer i-rmores tne fact that t Cftl4t.0 av’curacy -f I tnk~ atv :a;r le... azured in aitica1 nilios, of all thv straregic nuclear weaorjzf in CaC!. forCe iS CO c~aztd. V. (U) in order to utlijZe .he stanl1ard qra:pl.ic re

Controlling EPICS from a web browser.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Evans, K., Jr.

1999-04-13

An alternative to using a large graphical display manager like MEDM [1,2] to interface to a control system, is to use individual control objects, such as text boxes, meters, etc., running in a browser. This paper presents three implementations of this concept, one using ActiveX controls, one with Java applets, and another with Microsoft Agent. The ActiveX controls have performance nearing that of MEDM, but they only work on Windows platforms. The Java applets require a server to get around Web security restrictions and are not as fast, but they have the advantage of working on most platforms and withmore » both of the leading Web browsers. The agent works on Windows platforms with and without a browser and allows voice recognition and speech synthesis, making it somewhat more innovative than MEDM.« less

Windows 8: What Educators Need to Know

ERIC Educational Resources Information Center

Vedder, Richard G.

2012-01-01

In October 2012, Microsoft will release the commercial version of its next operating system, presently called "Windows 8." This version represents a significant departure from the past. Microsoft wants this operating system to meet user needs regardless of physical platform (e.g., desktop, notebook, tablet, mobile phone). As part of this mission,…

Corsica: A Multi-Mission Absolute Calibration Site

NASA Astrophysics Data System (ADS)

Bonnefond, P.; Exertier, P.; Laurain, O.; Guinle, T.; Femenias, P.

2013-09-01

In collaboration with the CNES and NASA oceanographic projects (TOPEX/Poseidon and Jason), the OCA (Observatoire de la Côte d'Azur) developed a verification site in Corsica since 1996, operational since 1998. CALibration/VALidation embraces a wide variety of activities, ranging from the interpretation of information from internal-calibration modes of the sensors to validation of the fully corrected estimates of the reflector heights using in situ data. Now, Corsica is, like the Harvest platform (NASA side) [14], an operating calibration site able to support a continuous monitoring with a high level of accuracy: a 'point calibration' which yields instantaneous bias estimates with a 10-day repeatability of 30 mm (standard deviation) and mean errors of 4 mm (standard error). For a 35-day repeatability (ERS, Envisat), due to a smaller time series, the standard error is about the double ( 7 mm).In this paper, we will present updated results of the absolute Sea Surface Height (SSH) biases for TOPEX/Poseidon (T/P), Jason-1, Jason-2, ERS-2 and Envisat.

Transplant Image Processing Technology under Windows into the Platform Based on MiniGUI

NASA Astrophysics Data System (ADS)

Gan, Lan; Zhang, Xu; Lv, Wenya; Yu, Jia

MFC has a large number of digital image processing-related API functions, object-oriented and class mechanisms which provides image processing technology strong support in Windows. But in embedded systems, image processing technology dues to the restrictions of hardware and software do not have the environment of MFC in Windows. Therefore, this paper draws on the experience of image processing technology of Windows and transplants it into MiniGUI embedded systems. The results show that MiniGUI/Embedded graphical user interface applications about image processing which used in embedded image processing system can be good results.

Monte Carlo verification of radiotherapy treatments with CloudMC.

PubMed

Miras, Hector; Jiménez, Rubén; Perales, Álvaro; Terrón, José Antonio; Bertolet, Alejandro; Ortiz, Antonio; Macías, José

2018-06-27

A new implementation has been made on CloudMC, a cloud-based platform presented in a previous work, in order to provide services for radiotherapy treatment verification by means of Monte Carlo in a fast, easy and economical way. A description of the architecture of the application and the new developments implemented is presented together with the results of the tests carried out to validate its performance. CloudMC has been developed over Microsoft Azure cloud. It is based on a map/reduce implementation for Monte Carlo calculations distribution over a dynamic cluster of virtual machines in order to reduce calculation time. CloudMC has been updated with new methods to read and process the information related to radiotherapy treatment verification: CT image set, treatment plan, structures and dose distribution files in DICOM format. Some tests have been designed in order to determine, for the different tasks, the most suitable type of virtual machines from those available in Azure. Finally, the performance of Monte Carlo verification in CloudMC is studied through three real cases that involve different treatment techniques, linac models and Monte Carlo codes. Considering computational and economic factors, D1_v2 and G1 virtual machines were selected as the default type for the Worker Roles and the Reducer Role respectively. Calculation times up to 33 min and costs of 16 € were achieved for the verification cases presented when a statistical uncertainty below 2% (2σ) was required. The costs were reduced to 3-6 € when uncertainty requirements are relaxed to 4%. Advantages like high computational power, scalability, easy access and pay-per-usage model, make Monte Carlo cloud-based solutions, like the one presented in this work, an important step forward to solve the long-lived problem of truly introducing the Monte Carlo algorithms in the daily routine of the radiotherapy planning process.

MONO FOR CROSS-PLATFORM CONTROL SYSTEM ENVIRONMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nishimura, Hiroshi; Timossi, Chris

2006-10-19

Mono is an independent implementation of the .NET Frameworkby Novell that runs on multiple operating systems (including Windows,Linux and Macintosh) and allows any .NET compatible application to rununmodified. For instance Mono can run programs with graphical userinterfaces (GUI) developed with the C# language on Windows with VisualStudio (a full port of WinForm for Mono is in progress). We present theresults of tests we performed to evaluate the portability of our controlssystem .NET applications from MS Windows to Linux.

Creating an X Window Terminal-Based Information Technology Center.

ERIC Educational Resources Information Center

Klassen, Tim W.

1997-01-01

The creation of an information technology center at the University of Oregon Science Library is described. Goals included providing access to Internet-based resources and multimedia software, platforms for running science-oriented software, and resources so students can create multimedia materials. A mixed-lab platform was created with Unix-based…

Method of high speed flow field influence and restrain on laser communication

NASA Astrophysics Data System (ADS)

Meng, Li-xin; Wang, Chun-hui; Qian, Cun-zhu; Wang, Shuo; Zhang, Li-zhong

2013-08-01

For laser communication performance which carried by airplane or airship, due to high-speed platform movement, the air has two influences in platform and laser communication terminal window. The first influence is that aerodynamic effect causes the deformation of the optical window; the second one is that a shock wave and boundary layer would be generated. For subsonic within the aircraft, the boundary layer is the main influence. The presence of a boundary layer could change the air density and the temperature of the optical window, which causes the light deflection and received beam spot flicker. Ultimately, the energy hunting of the beam spot which reaches receiving side increases, so that the error rate increases. In this paper, aerodynamic theory is used in analyzing the influence of the optical window deformation due to high speed air. Aero-optics theory is used to analyze the influence of the boundary layer in laser communication link. Based on this, we focused on working on exploring in aerodynamic and aero-optical effect suppression method in the perspective of the optical window design. Based on planning experimental aircraft types and equipment installation location, we optimized the design parameters of the shape and thickness of the optical window, the shape and size of air-management kit. Finally, deformation of the optical window and air flow distribution were simulated by fluid simulation software in the different mach and different altitude fly condition. The simulation results showed that the optical window can inhibit the aerodynamic influence after optimization. In addition, the boundary layer is smoothed; the turbulence influence is reduced, which meets the requirements of the airborne laser communication.

Software Intensive Systems

DTIC Science & Technology

2006-07-01

Architect, Developer and Platform Evangelism • Microsoft Dynamic Systems Initiative-- John Wilson, Architect Windows Management • Windows Lifecycle...Presentations • Aegis--Reuben Pitts & CDR John Ailes, Program Executive Office, Integrated Warfare Systems • Long Term Mine Reconnaissance (LMRS)--CAPT...Paul Imes • Joint Tactical Radio System (JTRS)--Richard North, JPEO JTRS & Leonard Schiavone , MITRE • Single Integrated Air Picture (SIAP)--CAPT

PC vs. Mac--Which Way Should You Go?

ERIC Educational Resources Information Center

Wodarz, Nan

1997-01-01

Outlines the factors in hardware, software, and administration to consider in developing specifications for choosing a computer operating system. Compares Microsoft Windows 95/NT that runs on PC/Intel-based systems and System 7.5 that runs on the Apple-based systems. Lists reasons why the Microsoft platform clearly stands above the Apple platform.…

The first sustainable material designed for air particulate matter capture: An introduction to Azure Chemistry.

PubMed

Zanoletti, A; Bilo, F; Depero, L E; Zappa, D; Bontempi, E

2018-07-15

This work presents a new porous material (SUNSPACE) designed for air particulate matter (PM) capture. It was developed in answer to the European Commission request of an innovative, affordable, and sustainable solution, based on design-driven material, to reduce the concentration of air particulate matter in urban areas. SUNSPACE material was developed from by-products and low-cost materials, such as silica fume and sodium alginate. Its capability to catch ultrafine PM was evaluated by different ad-hoc tests, considering diesel exhaust fumes and incense smoke PM. Despite the fact that procedures and materials can be designed for remediation, the high impact on the environment, for example in terms of natural resources consumption and emissions, are not usually considered. Instead, we believe that the technologies must be always evaluated in terms of material embodied energy (EE) and carbon footprint (CF). We define our approach to solve environment problems by a sustainable methodology "Azure Chemistry". For the SUNSPACE synthesis, the multi-criteria decision analysis was performed to select the best sustainable solution. The emissions and the energies involved in the synthesis of SUNSPACE material were evaluated with the Azure Chemistry approach, showing that this could be the best available technology to face the problem of capturing the PM in urban area. Copyright © 2018 Elsevier Ltd. All rights reserved.

Future Directions for Astronomical Image Display

NASA Technical Reports Server (NTRS)

Mandel, Eric

2000-01-01

In the "Future Directions for Astronomical Image Displav" project, the Smithsonian Astrophysical Observatory (SAO) and the National Optical Astronomy Observatories (NOAO) evolved our existing image display program into fully extensible. cross-platform image display software. We also devised messaging software to support integration of image display into astronomical analysis systems. Finally, we migrated our software from reliance on Unix and the X Window System to a platform-independent architecture that utilizes the cross-platform Tcl/Tk technology.

Centralized Monitoring of the Microsoft Windows-based computers of the LHC Experiment Control Systems

NASA Astrophysics Data System (ADS)

Varela Rodriguez, F.

2011-12-01

The control system of each of the four major Experiments at the CERN Large Hadron Collider (LHC) is distributed over up to 160 computers running either Linux or Microsoft Windows. A quick response to abnormal situations of the computer infrastructure is crucial to maximize the physics usage. For this reason, a tool was developed to supervise, identify errors and troubleshoot such a large system. Although the monitoring of the performance of the Linux computers and their processes was available since the first versions of the tool, it is only recently that the software package has been extended to provide similar functionality for the nodes running Microsoft Windows as this platform is the most commonly used in the LHC detector control systems. In this paper, the architecture and the functionality of the Windows Management Instrumentation (WMI) client developed to provide centralized monitoring of the nodes running different flavour of the Microsoft platform, as well as the interface to the SCADA software of the control systems are presented. The tool is currently being commissioned by the Experiments and it has already proven to be very efficient optimize the running systems and to detect misbehaving processes or nodes.

Implementing Audio-CASI on Windows’ Platforms

PubMed Central

Cooley, Philip C.; Turner, Charles F.

2011-01-01

Audio computer-assisted self interviewing (Audio-CASI) technologies have recently been shown to provide important and sometimes dramatic improvements in the quality of survey measurements. This is particularly true for measurements requiring respondents to divulge highly sensitive information such as their sexual, drug use, or other sensitive behaviors. However, DOS-based Audio-CASI systems that were designed and adopted in the early 1990s have important limitations. Most salient is the poor control they provide for manipulating the video presentation of survey questions. This article reports our experiences adapting Audio-CASI to Microsoft Windows 3.1 and Windows 95 platforms. Overall, our Windows-based system provided the desired control over video presentation and afforded other advantages including compatibility with a much wider array of audio devices than our DOS-based Audio-CASI technologies. These advantages came at the cost of increased system requirements --including the need for both more RAM and larger hard disks. While these costs will be an issue for organizations converting large inventories of PCS to Windows Audio-CASI today, this will not be a serious constraint for organizations and individuals with small inventories of machines to upgrade or those purchasing new machines today. PMID:22081743

SU-E-T-350: Verification of Gating Performance of a New Elekta Gating Solution: Response Kit and Catalyst System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, X; Cao, D; Housley, D

2014-06-01

Purpose: In this work, we have tested the performance of new respiratory gating solutions for Elekta linacs. These solutions include the Response gating and the C-RAD Catalyst surface mapping system.Verification measurements have been performed for a series of clinical cases. We also examined the beam on latency of the system and its impact on delivery efficiency. Methods: To verify the benefits of tighter gating windows, a Quasar Respiratory Motion Platform was used. Its vertical-motion plate acted as a respiration surrogate and was tracked by the Catalyst system to generate gating signals. A MatriXX ion-chamber array was mounted on its longitudinal-movingmore » platform. Clinical plans are delivered to a stationary and moving Matrix array at 100%, 50% and 30% gating windows and gamma scores were calculated comparing moving delivery results to the stationary result. It is important to note that as one moves to tighter gating windows, the delivery efficiency will be impacted by the linac's beam-on latency. Using a specialized software package, we generated beam-on signals of lengths of 1000ms, 600ms, 450ms, 400ms, 350ms and 300ms. As the gating windows get tighter, one can expect to reach a point where the dose rate will fall to nearly zero, indicating that the gating window is close to beam-on latency. A clinically useful gating window needs to be significantly longer than the latency for the linac. Results: As expected, the use of tighter gating windows improved delivery accuracy. However, a lower limit of the gating window, largely defined by linac beam-on latency, exists at around 300ms. Conclusion: The Response gating kit, combined with the C-RAD Catalyst, provides an effective solution for respiratorygated treatment delivery. Careful patient selection, gating window design, even visual/audio coaching may be necessary to ensure both delivery quality and efficiency. This research project is funded by Elekta.« less

Platform for Postprocessing Waveform-Based NDE

NASA Technical Reports Server (NTRS)

Roth, Don

2008-01-01

Taking advantage of the similarities that exist among all waveform-based non-destructive evaluation (NDE) methods, a common software platform has been developed containing multiple- signal and image-processing techniques for waveforms and images. The NASA NDE Signal and Image Processing software has been developed using the latest versions of LabVIEW, and its associated Advanced Signal Processing and Vision Toolkits. The software is useable on a PC with Windows XP and Windows Vista. The software has been designed with a commercial grade interface in which two main windows, Waveform Window and Image Window, are displayed if the user chooses a waveform file to display. Within these two main windows, most actions are chosen through logically conceived run-time menus. The Waveform Window has plots for both the raw time-domain waves and their frequency- domain transformations (fast Fourier transform and power spectral density). The Image Window shows the C-scan image formed from information of the time-domain waveform (such as peak amplitude) or its frequency-domain transformation at each scan location. The user also has the ability to open an image, or series of images, or a simple set of X-Y paired data set in text format. Each of the Waveform and Image Windows contains menus from which to perform many user actions. An option exists to use raw waves obtained directly from scan, or waves after deconvolution if system wave response is provided. Two types of deconvolution, time-based subtraction or inverse-filter, can be performed to arrive at a deconvolved wave set. Additionally, the menu on the Waveform Window allows preprocessing of waveforms prior to image formation, scaling and display of waveforms, formation of different types of images (including non-standard types such as velocity), gating of portions of waves prior to image formation, and several other miscellaneous and specialized operations. The menu available on the Image Window allows many further image processing and analysis operations, some of which are found in commercially-available image-processing software programs (such as Adobe Photoshop), and some that are not (removing outliers, Bscan information, region-of-interest analysis, line profiles, and precision feature measurements).

RELAP5-3D developmental assessment: Comparison of version 4.2.1i on Linux and Windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bayless, Paul D.

2014-06-01

Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code, version 4.2i, compiled on Linux and Windows platforms. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions differ between the Linux and Windows versions.

RELAP5-3D Developmental Assessment. Comparison of Version 4.3.4i on Linux and Windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bayless, Paul David

2015-10-01

Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code, version 4.3i, compiled on Linux and Windows platforms. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions differ between the Linux and Windows versions.

Development, Qualification and Production of Space Solar Cells with 30% EOL Efficiency

NASA Astrophysics Data System (ADS)

Guter, Wolfgang; Ebel, Lars; Fuhrmann, Daniel; Kostler, Wolfgang; Meusel, Matthias

2014-08-01

AZUR SPACE's latest qualified solar cell product 3G30-advanced provides a high end-of-life (EOL) efficiency of 27.8% for 5E14 (1 MeV e-/cm2) at low production costs. In order to further reduce the mass, the 3G30-advanced was thinned down to as thin as 20 μm and tested in space. Next generation solar cells must exceed the EOL efficiency of the 3G30-advanced and therefore will utilize the excess current of the Ge subcell. This can be achieved by a metamorphic cell concept. While average beginning-of-life efficiencies above 31% have already been demonstrated with upright metamorphic triple-junction cells, AZUR's next generation product will comprise a metamorphic 4- junction device targeting 30% EOL.

Manufacturing and metrology for IR conformal windows and domes

NASA Astrophysics Data System (ADS)

Ferralli, Ian; Blalock, Todd; Brunelle, Matt; Lynch, Timothy; Myer, Brian; Medicus, Kate

2017-05-01

Freeform and conformal optics have the potential to dramatically improve optical systems by enabling systems with fewer optical components, reduced aberrations, and improved aerodynamic performance. These optical components differ from standard components in their surface shape, typically a non-symmetric equation based definition, and material properties. Traditional grinding and polishing tools are unable to handle these freeform shapes. Additionally, standard metrology tools cannot measure these surfaces. Desired substrates are typically hard ceramics, including poly-crystalline alumina or aluminum oxynitride. Notwithstanding the challenges that the hardness provides to manufacturing, these crystalline materials can be highly susceptible to grain decoration creating unacceptable scatter in optical systems. In this presentation, we will show progress towards addressing the unique challenges of manufacturing conformal windows and domes. Particular attention is given to our robotic polishing platform. This platform is based on an industrial robot adapted to accept a wide range of tooling and parts. The robot's flexibility has provided us an opportunity to address the unique challenges of conformal windows. Slurries and polishing active layers can easily be changed to adapt to varying materials and address grain decoration. We have the flexibility to change tool size and shape to address the varying sizes and shapes of conformal optics. In addition, the robotic platform can be a base for a deflectometry-based metrology tool to measure surface form error. This system, whose precision is independent of the robot's positioning accuracy, will allow us to measure optics in-situ saving time and reducing part risk. In conclusion, we will show examples of the conformal windows manufactured using our developed processes.

minimega

DOE Office of Scientific and Technical Information (OSTI.GOV)

David Fritz, John Floren

2013-08-27

Minimega is a simple emulytics platform for creating testbeds of networked devices. The platform consists of easily deployable tools to facilitate bringing up large networks of virtual machines including Windows, Linux, and Android. Minimega attempts to allow experiments to be brought up quickly with nearly no configuration. Minimega also includes tools for simple cluster management, as well as tools for creating Linux based virtual machine images.

High-impact resistance optical sensor windows

NASA Astrophysics Data System (ADS)

Askinazi, Joel; Ceccorulli, Mark L.; Goldman, Lee

2011-06-01

Recent field experience with optical sensor windows on both ground and airborne platforms has shown a significant increase in window fracturing from foreign object debris (FOD) impacts and as a by-product of asymmetrical warfare. Common optical sensor window materials such as borosilicate glass do not typically have high impact resistance. Emerging advanced optical window materials such as aluminum oxynitride offer the potential for a significant improvement in FOD impact resistance due to their superior surface hardness, fracture toughness and strength properties. To confirm the potential impact resistance improvement achievable with these emerging materials, Goodrich ISR Systems in collaboration with Surmet Corporation undertook a set of comparative FOD impact tests of optical sensor windows made from borosilicate glass and from aluminum oxynitride. It was demonstrated that the aluminum oxynitride windows could withstand up to three times the FOD impact velocity (as compared with borosilicate glass) before fracture would occur. These highly encouraging test results confirm the utility of this new highly viable window solution for use on new ground and airborne window multispectral applications as well as a retrofit to current production windows. We believe that this solution can go a long way to significantly reducing the frequency and life cycle cost of window replacement.

Benchmarks for Enhanced Network Performance: Hands-On Testing of Operating System Solutions to Identify the Optimal Application Server Platform for the Graduate School of Business and Public Policy

DTIC Science & Technology

2010-09-01

for Applied Mathematics. Kennedy, R. C. (2009a). Clocking Windows netbook performance. Retrieved on 08/14/2010, from http...podcasts.infoworld.com/d/hardware/clocking-windows- netbook -performance-883?_kip_ipx=1177119066-1281460794 Kennedy, R. C. (2009b). OfficeBench 7: A cool new way to

H2S induced coma and cardiogenic shock in the rat: Effects of phenothiazinium chromophores

PubMed Central

SONOBE, TAKASHI; HAOUZI, PHILIPPE

2015-01-01

Context Hydrogen sulfide (H2S) intoxication produces an acute depression in cardiac contractility-induced circulatory failure, which has been shown to be one of the major contributors to the lethality of H2S intoxication or to the neurological sequelae in surviving animals. Methylene blue (MB), a phenothiazinium dye, can antagonize the effects of the inhibition of mitochondrial electron transport chain, a major effect of H2S toxicity. Objectives We investigated whether MB could affect the immediate outcome of H2S-induced coma in unanesthetized animals. Second, we sought to characterize the acute cardiovascular effects of MB and two of its demethylated metabolites—azure B and thionine—in anesthetized rats during lethal infusion of H2S. Materials and methods First, MB (4 mg/kg, intravenous [IV]) was administered in non-sedated rats during the phase of agonal breathing, following NaHS (20 mg/kg, IP)-induced coma. Second, in 4 groups of urethane-anesthetized rats, NaHS was infused at a rate lethal within 10 min (0.8 mg/min, IV). Whenever cardiac output (CO) reached 40% of its baseline volume, MB, azure B, thionine, or saline were injected, while sulfide infusion was maintained until cardiac arrest occurred. Results Seventy-five percent of the comatose rats that received saline (n = 8) died within 7 min, while all the 7 rats that were given MB survived (p = 0.007). In the anesthetized rats, arterial, left ventricular pressures and CO decreased during NaHS infusion, leading to a pulseless electrical activity within 530 s. MB produced a significant increase in CO and dP/dtmax for about 2 min. A similar effect was produced when MB was also injected in the pre-mortem phase of sulfide exposure, significantly increasing survival time. Azure B produced an even larger increase in blood pressure than MB, while thionine had no effect. Conclusion MB can counteract NaHS-induced acute cardiogenic shock; this effect is also produced by azure B, but not by thionine, suggesting that the presence of methyl groups is a prerequisite for producing this protective effect. PMID:25965774

Fabrication of Microcapsules for Dye-Doped Polymer-Dispersed Liquid Crystal-Based Smart Windows.

PubMed

Kim, Mingyun; Park, Kyun Joo; Seok, Seunghwan; Ok, Jong Min; Jung, Hee-Tae; Choe, Jaehoon; Kim, Do Hyun

2015-08-19

A dye-doped polymer-dispersed liquid crystal (PDLC) is an attractive material for application in smart windows. Smart windows using a PDLC can be operated simply and have a high contrast ratio compared to those of other devices that employed photochromic or thermochromic material. However, in conventional dye-doped PDLC methods, dye contamination can cause problems and has a limited degree of commercialization of electric smart windows. Here, we report on an approach to resolve dye-related problems by encapsulating the dye in monodispersed capsules. By encapsulation, a fabricated dye-doped PDLC had a contrast ratio of >120 at 600 nm. This fabrication method of encapsulating the dye in a core-shell structured microcapsule in a dye-doped PDLC device provides a practical platform for dye-doped PDLC-based smart windows.

A Set of Free Cross-Platform Authoring Programs for Flexible Web-Based CALL Exercises

ERIC Educational Resources Information Center

O'Brien, Myles

2012-01-01

The Mango Suite is a set of three freely downloadable cross-platform authoring programs for flexible network-based CALL exercises. They are Adobe Air applications, so they can be used on Windows, Macintosh, or Linux computers, provided the freely-available Adobe Air has been installed on the computer. The exercises which the programs generate are…

REEF: Retainable Evaluator Execution Framework

PubMed Central

Weimer, Markus; Chen, Yingda; Chun, Byung-Gon; Condie, Tyson; Curino, Carlo; Douglas, Chris; Lee, Yunseong; Majestro, Tony; Malkhi, Dahlia; Matusevych, Sergiy; Myers, Brandon; Narayanamurthy, Shravan; Ramakrishnan, Raghu; Rao, Sriram; Sears, Russell; Sezgin, Beysim; Wang, Julia

2015-01-01

Resource Managers like Apache YARN have emerged as a critical layer in the cloud computing system stack, but the developer abstractions for leasing cluster resources and instantiating application logic are very low-level. This flexibility comes at a high cost in terms of developer effort, as each application must repeatedly tackle the same challenges (e.g., fault-tolerance, task scheduling and coordination) and re-implement common mechanisms (e.g., caching, bulk-data transfers). This paper presents REEF, a development framework that provides a control-plane for scheduling and coordinating task-level (data-plane) work on cluster resources obtained from a Resource Manager. REEF provides mechanisms that facilitate resource re-use for data caching, and state management abstractions that greatly ease the development of elastic data processing work-flows on cloud platforms that support a Resource Manager service. REEF is being used to develop several commercial offerings such as the Azure Stream Analytics service. Furthermore, we demonstrate REEF development of a distributed shell application, a machine learning algorithm, and a port of the CORFU [4] system. REEF is also currently an Apache Incubator project that has attracted contributors from several instititutions.1 PMID:26819493

Folding Proteins at 500 ns/hour with Work Queue.

PubMed

Abdul-Wahid, Badi'; Yu, Li; Rajan, Dinesh; Feng, Haoyun; Darve, Eric; Thain, Douglas; Izaguirre, Jesús A

2012-10-01

Molecular modeling is a field that traditionally has large computational costs. Until recently, most simulation techniques relied on long trajectories, which inherently have poor scalability. A new class of methods is proposed that requires only a large number of short calculations, and for which minimal communication between computer nodes is required. We considered one of the more accurate variants called Accelerated Weighted Ensemble Dynamics (AWE) and for which distributed computing can be made efficient. We implemented AWE using the Work Queue framework for task management and applied it to an all atom protein model (Fip35 WW domain). We can run with excellent scalability by simultaneously utilizing heterogeneous resources from multiple computing platforms such as clouds (Amazon EC2, Microsoft Azure), dedicated clusters, grids, on multiple architectures (CPU/GPU, 32/64bit), and in a dynamic environment in which processes are regularly added or removed from the pool. This has allowed us to achieve an aggregate sampling rate of over 500 ns/hour. As a comparison, a single process typically achieves 0.1 ns/hour.

Folding Proteins at 500 ns/hour with Work Queue

PubMed Central

Abdul-Wahid, Badi’; Yu, Li; Rajan, Dinesh; Feng, Haoyun; Darve, Eric; Thain, Douglas; Izaguirre, Jesús A.

2014-01-01

Molecular modeling is a field that traditionally has large computational costs. Until recently, most simulation techniques relied on long trajectories, which inherently have poor scalability. A new class of methods is proposed that requires only a large number of short calculations, and for which minimal communication between computer nodes is required. We considered one of the more accurate variants called Accelerated Weighted Ensemble Dynamics (AWE) and for which distributed computing can be made efficient. We implemented AWE using the Work Queue framework for task management and applied it to an all atom protein model (Fip35 WW domain). We can run with excellent scalability by simultaneously utilizing heterogeneous resources from multiple computing platforms such as clouds (Amazon EC2, Microsoft Azure), dedicated clusters, grids, on multiple architectures (CPU/GPU, 32/64bit), and in a dynamic environment in which processes are regularly added or removed from the pool. This has allowed us to achieve an aggregate sampling rate of over 500 ns/hour. As a comparison, a single process typically achieves 0.1 ns/hour. PMID:25540799

xdamp Version 6 : an IDL-based data and image manipulation program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ballard, William Parker

2012-04-01

The original DAMP (DAta Manipulation Program) was written by Mark Hedemann of Sandia National Laboratories and used the CA-DISSPLA{trademark} (available from Computer Associates International, Inc., Garden City, NY) graphics package as its engine. It was used to plot, modify, and otherwise manipulate the one-dimensional data waveforms (data vs. time) from a wide variety of accelerators. With the waning of CA-DISSPLA and the increasing popularity of Unix(reg sign)-based workstations, a replacement was needed. This package uses the IDL(reg sign) software, available from Research Systems Incorporated, a Xerox company, in Boulder, Colorado, as the engine, and creates a set of widgets tomore » manipulate the data in a manner similar to the original DAMP and earlier versions of xdamp. IDL is currently supported on a wide variety of Unix platforms such as IBM(reg sign) workstations, Hewlett Packard workstations, SUN(reg sign) workstations, Microsoft(reg sign) Windows{trademark} computers, Macintosh(reg sign) computers and Digital Equipment Corporation VMS(reg sign) and Alpha(reg sign) systems. Thus, xdamp is portable across many platforms. We have verified operation, albeit with some minor IDL bugs, on personal computers using Windows 7 and Windows Vista; Unix platforms; and Macintosh computers. Version 6 is an update that uses the IDL Virtual Machine to resolve the need for licensing IDL.« less

Castine Report S-15 Project: Shipbuilding Standards

DTIC Science & Technology

1976-01-01

Fixed Square Windows Ships” Extruded Aluminium Alloy Square Windows “ Ships” Foot Steps Ships* Wooden Hand Rail . Pilot Ladders Panama Canal Pilot...Platforms Aluminium Alloy Accommodation Ladders Mouth Pieces for Voice Tube Chain Drwe Type Telegraphs Fittings for Steam Whistle Llfeboats Radial Type...Cast Steel Angle Valves for Compressed Air F 8001-1957 F 8002-1967 F 8003.1975 F 8004.1975 F 8011 1966 F 8013.1969 F 8101.1969 F 8401.1970 F

Migration of the Three-dimensional Wind Field (3DWF) Model from Linux to Windows and Mobile Platforms

DTIC Science & Technology

2017-11-01

7 Fig. 10 Build executable code ........................................................................... 8 Fig. 11 3DWF GUI’s main web ...can be designed in any Windows operating system with internet access via Microsoft’s Internet Explorer (IE) web browser. For this particular project...Therefore, it is advised to have network security safeguards in place and operate only in a trusted PC. The GUI’s Hypertext Markup Language (HTML) web

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms.

PubMed

Kumar, Sudhir; Stecher, Glen; Li, Michael; Knyaz, Christina; Tamura, Koichiro

2018-06-01

The Molecular Evolutionary Genetics Analysis (Mega) software implements many analytical methods and tools for phylogenomics and phylomedicine. Here, we report a transformation of Mega to enable cross-platform use on Microsoft Windows and Linux operating systems. Mega X does not require virtualization or emulation software and provides a uniform user experience across platforms. Mega X has additionally been upgraded to use multiple computing cores for many molecular evolutionary analyses. Mega X is available in two interfaces (graphical and command line) and can be downloaded from www.megasoftware.net free of charge.

Closeup view of the exterior of the starboard side of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view of the exterior of the starboard side of the forward fuselage of the Orbiter Discovery looking at the forward facing observation windows of the flight deck. Note the High-temperature Reusable Surface Insulation (HRSI) surrounding the window openings, the Low-temperature Reusable Surface Insulation (LRSI) immediately beyond the HRSI tiles and the Advanced Flexible Reusable Surface Insulation blankets just beyond the LRSI tiles. The holes in the tiles are injection points for the application of waterproofing material. The windows are composed of redundant pressure window panes of thermal glass. This image was taken from a service platform in the Orbiter Processing Facility at Kennedy Space Center - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

15 CFR 1.2 - Description and design.

Code of Federal Regulations, 2010 CFR

2010-01-01

... fesse azure and or, a ship in full sail on waves of the sea, in chief proper; and in base a lighthouse... issued with the President's approval of the seal, made necessary by changes in the functions of the...

Probing Electron Transfer Mechanisms in Shewanella oneidensis MR-1 using a Nanoelectrode Platform and Single-Cell Imaging

DTIC Science & Technology

2010-01-01

investigate extracellu- lar electron transfer in Shewanella oneidensisMR-1,where an array of nanoholes precludes or single window allows for direct...the single-cell level (Fig. 1B) highlights the re- lative sizes of the nanohole and window openings in the insulating layer deposited over electrodes...relative to individual bacteria such as Shewanella. The nanoholes are sufficiently small to preclude direct contact of the bacterial cell body to the

Volume balance and toxicity analysis for the cross lake bridge.

DOT National Transportation Integrated Search

2009-09-01

There were two overall objectives for this project: (1) to assess leakage from the bridge once repairs to the collection system were completed and (2) to investigate Microtox, a toxicity screening tool manufactured by Azur environmental, as a m...

Uncover the Cloud for Geospatial Sciences and Applications to Adopt Cloud Computing

NASA Astrophysics Data System (ADS)

Yang, C.; Huang, Q.; Xia, J.; Liu, K.; Li, J.; Xu, C.; Sun, M.; Bambacus, M.; Xu, Y.; Fay, D.

2012-12-01

Cloud computing is emerging as the future infrastructure for providing computing resources to support and enable scientific research, engineering development, and application construction, as well as work force education. On the other hand, there is a lot of doubt about the readiness of cloud computing to support a variety of scientific research, development and educations. This research is a project funded by NASA SMD to investigate through holistic studies how ready is the cloud computing to support geosciences. Four applications with different computing characteristics including data, computing, concurrent, and spatiotemporal intensities are taken to test the readiness of cloud computing to support geosciences. Three popular and representative cloud platforms including Amazon EC2, Microsoft Azure, and NASA Nebula as well as a traditional cluster are utilized in the study. Results illustrates that cloud is ready to some degree but more research needs to be done to fully implemented the cloud benefit as advertised by many vendors and defined by NIST. Specifically, 1) most cloud platform could help stand up new computing instances, a new computer, in a few minutes as envisioned, therefore, is ready to support most computing needs in an on demand fashion; 2) the load balance and elasticity, a defining characteristic, is ready in some cloud platforms, such as Amazon EC2, to support bigger jobs, e.g., needs response in minutes, while some are not ready to support the elasticity and load balance well. All cloud platform needs further research and development to support real time application at subminute level; 3) the user interface and functionality of cloud platforms vary a lot and some of them are very professional and well supported/documented, such as Amazon EC2, some of them needs significant improvement for the general public to adopt cloud computing without professional training or knowledge about computing infrastructure; 4) the security is a big concern in cloud computing platform, with the sharing spirit of cloud computing, it is very hard to ensure higher level security, except a private cloud is built for a specific organization without public access, public cloud platform does not support FISMA medium level yet and may never be able to support FISMA high level; 5) HPC jobs needs of cloud computing is not well supported and only Amazon EC2 supports this well. The research is being taken by NASA and other agencies to consider cloud computing adoption. We hope the publication of the research would also benefit the public to adopt cloud computing.

Azure Avery | NREL

Science.gov Websites

of her dissertation research, Dr. Avery probed thermoelectric effects such as the Seebeck effect and .; Zink, B.L. (2011). "Thermopower and Resistivity in Ferromagnetic Thin Films Near Room Temperature Thermoelectric Effects and Wiedemann-Franz Violation in Magnetic Nanostructures via Micromachined Thermal

Development of a cryogenically cooled platform for the Magnetized Liner Inertial Fusion (MagLIF) Program [Development of a cryogenically-cooled platform for the Magnetized Liner Inertial Fusion (MagLIF) Concept

DOE PAGES

Awe, T. J.; Shelton, K. P.; Sefkow, A. B.; ...

2017-09-25

A cryogenically cooled hardware platform has been developed and commissioned on the Z Facility at Sandia National Laboratories in support of the Magnetized Liner Inertial Fusion (MagLIF) Program. MagLIF is a magneto-inertial fusion concept that employs a magnetically imploded metallic tube (liner) to compress and inertially confine premagnetized and preheated fusion fuel. The fuel is preheated using a ~2 kJ laser that must pass through a ~1.5-3.5-μm-thick polyimide “window” at the target’s laser entrance hole (LEH). As the terawatt-class laser interacts with the dense window, laser plasma instabilities (LPIs) can develop, which reduce the preheat energy delivered to the fuel,more » initiate fuel contamination, and degrade target performance. Cryogenically cooled targets increase the parameter space accessible to MagLIF target designs by allowing nearly 10 times thinner windows to be used for any accessible gas density. Thinner LEH windows reduce the deleterious effects of difficult to model LPIs. The Z Facility’s cryogenic infrastructure has been significantly altered to enable compatibility with the premagnetization and fuel preheat stages of MagLIF. The MagLIF cryostat brings the liquid helium coolant directly to the target via an electrically resistive conduit. This design maximizes cooling power while allowing rapid diffusion of the axial magnetic field supplied by external Helmholtz-like coils. A variety of techniques have been developed to mitigate the accumulation of ice from vacuum chamber contaminants on the cooled LEH window, as even a few hundred nanometers of ice would impact laser energy coupling to the fuel region. Here, the MagLIF cryostat has demonstrated compatibility with the premagnetization and preheat stages of MagLIF and the ability to cool targets to liquid deuterium temperatures in approximately 5 min.« less

Development of a cryogenically cooled platform for the Magnetized Liner Inertial Fusion (MagLIF) Program [Development of a cryogenically-cooled platform for the Magnetized Liner Inertial Fusion (MagLIF) Concept

DOE Office of Scientific and Technical Information (OSTI.GOV)

Awe, T. J.; Shelton, K. P.; Sefkow, A. B.

A cryogenically cooled hardware platform has been developed and commissioned on the Z Facility at Sandia National Laboratories in support of the Magnetized Liner Inertial Fusion (MagLIF) Program. MagLIF is a magneto-inertial fusion concept that employs a magnetically imploded metallic tube (liner) to compress and inertially confine premagnetized and preheated fusion fuel. The fuel is preheated using a ~2 kJ laser that must pass through a ~1.5-3.5-μm-thick polyimide “window” at the target’s laser entrance hole (LEH). As the terawatt-class laser interacts with the dense window, laser plasma instabilities (LPIs) can develop, which reduce the preheat energy delivered to the fuel,more » initiate fuel contamination, and degrade target performance. Cryogenically cooled targets increase the parameter space accessible to MagLIF target designs by allowing nearly 10 times thinner windows to be used for any accessible gas density. Thinner LEH windows reduce the deleterious effects of difficult to model LPIs. The Z Facility’s cryogenic infrastructure has been significantly altered to enable compatibility with the premagnetization and fuel preheat stages of MagLIF. The MagLIF cryostat brings the liquid helium coolant directly to the target via an electrically resistive conduit. This design maximizes cooling power while allowing rapid diffusion of the axial magnetic field supplied by external Helmholtz-like coils. A variety of techniques have been developed to mitigate the accumulation of ice from vacuum chamber contaminants on the cooled LEH window, as even a few hundred nanometers of ice would impact laser energy coupling to the fuel region. Here, the MagLIF cryostat has demonstrated compatibility with the premagnetization and preheat stages of MagLIF and the ability to cool targets to liquid deuterium temperatures in approximately 5 min.« less

Web interfaces to relational databases

NASA Technical Reports Server (NTRS)

Carlisle, W. H.

1996-01-01

This reports on a project to extend the capabilities of a Virtual Research Center (VRC) for NASA's Advanced Concepts Office. The work was performed as part of NASA's 1995 Summer Faculty Fellowship program and involved the development of a prototype component of the VRC - a database system that provides data creation and access services within a room of the VRC. In support of VRC development, NASA has assembled a laboratory containing the variety of equipment expected to be used by scientists within the VRC. This laboratory consists of the major hardware platforms, SUN, Intel, and Motorola processors and their most common operating systems UNIX, Windows NT, Windows for Workgroups, and Macintosh. The SPARC 20 runs SUN Solaris 2.4, an Intel Pentium runs Windows NT and is installed on a different network from the other machines in the laboratory, a Pentium PC runs Windows for Workgroups, two Intel 386 machines run Windows 3.1, and finally, a PowerMacintosh and a Macintosh IIsi run MacOS.

Windows Instant Messaging App Forensics: Facebook and Skype as Case Studies

PubMed Central

Yang, Teing Yee; Dehghantanha, Ali; Choo, Kim-Kwang Raymond; Muda, Zaiton

2016-01-01

Instant messaging (IM) has changed the way people communicate with each other. However, the interactive and instant nature of these applications (apps) made them an attractive choice for malicious cyber activities such as phishing. The forensic examination of IM apps for modern Windows 8.1 (or later) has been largely unexplored, as the platform is relatively new. In this paper, we seek to determine the data remnants from the use of two popular Windows Store application software for instant messaging, namely Facebook and Skype on a Windows 8.1 client machine. This research contributes to an in-depth understanding of the types of terrestrial artefacts that are likely to remain after the use of instant messaging services and application software on a contemporary Windows operating system. Potential artefacts detected during the research include data relating to the installation or uninstallation of the instant messaging application software, log-in and log-off information, contact lists, conversations, and transferred files. PMID:26982207

Windows Instant Messaging App Forensics: Facebook and Skype as Case Studies.

PubMed

Yang, Teing Yee; Dehghantanha, Ali; Choo, Kim-Kwang Raymond; Muda, Zaiton

2016-01-01

Instant messaging (IM) has changed the way people communicate with each other. However, the interactive and instant nature of these applications (apps) made them an attractive choice for malicious cyber activities such as phishing. The forensic examination of IM apps for modern Windows 8.1 (or later) has been largely unexplored, as the platform is relatively new. In this paper, we seek to determine the data remnants from the use of two popular Windows Store application software for instant messaging, namely Facebook and Skype on a Windows 8.1 client machine. This research contributes to an in-depth understanding of the types of terrestrial artefacts that are likely to remain after the use of instant messaging services and application software on a contemporary Windows operating system. Potential artefacts detected during the research include data relating to the installation or uninstallation of the instant messaging application software, log-in and log-off information, contact lists, conversations, and transferred files.

Sulfogalactosylglycerolipid is involved in human gamete interaction.

PubMed

Weerachatyanukul, W; Rattanachaiyanont, M; Carmona, E; Furimsky, A; Mai, A; Shoushtarian, A; Sirichotiyakul, S; Ballakier, H; Leader, A; Tanphaichitr, N

2001-12-01

Recent results from our laboratory have revealed the role of sulfogalactosylglycerolipid (SGG) in mouse sperm-zona pellucida (ZP) binding. In this report, we demonstrated the presence of SGG in Percoll-gradient centrifuged (PGC) human sperm by high performance thin layer chromatography with orcinol and Azure A staining, specific for glycolipids and sulfolipids, respectively. SGG in human PGC sperm was quantified by its affinity to Azure A to be 12-15 mol% of sperm lipids. Indirect immunofluorescence revealed that SGG existed on both live and aldehyde fixed human sperm in the head region. Pretreatment of human PGC sperm with affinity purified antiSGG Fab markedly inhibited sperm binding to the ZP in a concentration dependent manner, without any changes in the spontaneous acrosome rate or sperm motility parameters. Fluorescently labeled SGG liposomes also bound uniformly to isolated human ZP, while fluorescently labeled galactosylglycerolipid (GG, SGG's parental lipid) or phosphatidylserine (PS, negatively charged like SGG) liposomes did not. All of these results suggested the role of human sperm SGG in ZP binding. Copyright 2001 Wiley-Liss, Inc.

Surviving sepsis--a 3D integrative educational simulator.

PubMed

Ježek, Filip; Tribula, Martin; Kulhánek, Tomáš; Mateják, Marek; Privitzer, Pavol; Šilar, Jan; Kofránek, Jiří; Lhotská, Lenka

2015-08-01

Computer technology offers greater educational possibilities, notably simulation and virtual reality. This paper presents a technology which serves to integrate multiple modalities, namely 3D virtual reality, node-based simulator, Physiomodel explorer and explanatory physiological simulators employing Modelica language and Unity3D platform. This emerging tool chain should allow the authors to concentrate more on educational content instead of application development. The technology is demonstrated through Surviving sepsis educational scenario, targeted on Microsoft Windows Store platform.

A Dedicated Computational Platform for Cellular Monte Carlo T-CAD Software Tools

DTIC Science & Technology

2015-07-14

computer that establishes an encrypted Virtual Private Network ( OpenVPN [44]) based on the Secure Socket Layer (SSL) paradigm. Each user is given a...security certificate for each device used to connect to the computing nodes. Stable OpenVPN clients are available for Linux, Microsoft Windows, Apple OSX...platform is granted by an encrypted connection base on the Secure Socket Layer (SSL) protocol, and implemented in the OpenVPN Virtual Personal Network

GUIdock: Using Docker Containers with a Common Graphics User Interface to Address the Reproducibility of Research

PubMed Central

Yeung, Ka Yee

2016-01-01

Reproducibility is vital in science. For complex computational methods, it is often necessary, not just to recreate the code, but also the software and hardware environment to reproduce results. Virtual machines, and container software such as Docker, make it possible to reproduce the exact environment regardless of the underlying hardware and operating system. However, workflows that use Graphical User Interfaces (GUIs) remain difficult to replicate on different host systems as there is no high level graphical software layer common to all platforms. GUIdock allows for the facile distribution of a systems biology application along with its graphics environment. Complex graphics based workflows, ubiquitous in systems biology, can now be easily exported and reproduced on many different platforms. GUIdock uses Docker, an open source project that provides a container with only the absolutely necessary software dependencies and configures a common X Windows (X11) graphic interface on Linux, Macintosh and Windows platforms. As proof of concept, we present a Docker package that contains a Bioconductor application written in R and C++ called networkBMA for gene network inference. Our package also includes Cytoscape, a java-based platform with a graphical user interface for visualizing and analyzing gene networks, and the CyNetworkBMA app, a Cytoscape app that allows the use of networkBMA via the user-friendly Cytoscape interface. PMID:27045593

GUIdock: Using Docker Containers with a Common Graphics User Interface to Address the Reproducibility of Research.

PubMed

Hung, Ling-Hong; Kristiyanto, Daniel; Lee, Sung Bong; Yeung, Ka Yee

2016-01-01

Reproducibility is vital in science. For complex computational methods, it is often necessary, not just to recreate the code, but also the software and hardware environment to reproduce results. Virtual machines, and container software such as Docker, make it possible to reproduce the exact environment regardless of the underlying hardware and operating system. However, workflows that use Graphical User Interfaces (GUIs) remain difficult to replicate on different host systems as there is no high level graphical software layer common to all platforms. GUIdock allows for the facile distribution of a systems biology application along with its graphics environment. Complex graphics based workflows, ubiquitous in systems biology, can now be easily exported and reproduced on many different platforms. GUIdock uses Docker, an open source project that provides a container with only the absolutely necessary software dependencies and configures a common X Windows (X11) graphic interface on Linux, Macintosh and Windows platforms. As proof of concept, we present a Docker package that contains a Bioconductor application written in R and C++ called networkBMA for gene network inference. Our package also includes Cytoscape, a java-based platform with a graphical user interface for visualizing and analyzing gene networks, and the CyNetworkBMA app, a Cytoscape app that allows the use of networkBMA via the user-friendly Cytoscape interface.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rudkevich, Aleksandr; Goldis, Evgeniy

This research conducted by the Newton Energy Group, LLC (NEG) is dedicated to the development of pCloud: a Cloud-based Power Market Simulation Environment. pCloud is offering power industry stakeholders the capability to model electricity markets and is organized around the Software as a Service (SaaS) concept -- a software application delivery model in which software is centrally hosted and provided to many users via the internet. During the Phase I of this project NEG developed a prototype design for pCloud as a SaaS-based commercial service offering, system architecture supporting that design, ensured feasibility of key architecture's elements, formed technological partnershipsmore » and negotiated commercial agreements with partners, conducted market research and other related activities and secured funding for continue development of pCloud between the end of Phase I and beginning of Phase II, if awarded. Based on the results of Phase I activities, NEG has established that the development of a cloud-based power market simulation environment within the Windows Azure platform is technologically feasible, can be accomplished within the budget and timeframe available through the Phase II SBIR award with additional external funding. NEG believes that pCloud has the potential to become a game-changing technology for the modeling and analysis of electricity markets. This potential is due to the following critical advantages of pCloud over its competition: - Standardized access to advanced and proven power market simulators offered by third parties. - Automated parallelization of simulations and dynamic provisioning of computing resources on the cloud. This combination of automation and scalability dramatically reduces turn-around time while offering the capability to increase the number of analyzed scenarios by a factor of 10, 100 or even 1000. - Access to ready-to-use data and to cloud-based resources leading to a reduction in software, hardware, and IT costs. - Competitive pricing structure, which will make high-volume usage of simulation services affordable. - Availability and affordability of high quality power simulators, which presently only large corporate clients can afford, will level the playing field in developing regional energy policies, determining prudent cost recovery mechanisms and assuring just and reasonable rates to consumers. - Users that presently do not have the resources to internally maintain modeling capabilities will now be able to run simulations. This will invite more players into the industry, ultimately leading to more transparent and liquid power markets.« less

MC-GenomeKey: a multicloud system for the detection and annotation of genomic variants.

PubMed

Elshazly, Hatem; Souilmi, Yassine; Tonellato, Peter J; Wall, Dennis P; Abouelhoda, Mohamed

2017-01-20

Next Generation Genome sequencing techniques became affordable for massive sequencing efforts devoted to clinical characterization of human diseases. However, the cost of providing cloud-based data analysis of the mounting datasets remains a concerning bottleneck for providing cost-effective clinical services. To address this computational problem, it is important to optimize the variant analysis workflow and the used analysis tools to reduce the overall computational processing time, and concomitantly reduce the processing cost. Furthermore, it is important to capitalize on the use of the recent development in the cloud computing market, which have witnessed more providers competing in terms of products and prices. In this paper, we present a new package called MC-GenomeKey (Multi-Cloud GenomeKey) that efficiently executes the variant analysis workflow for detecting and annotating mutations using cloud resources from different commercial cloud providers. Our package supports Amazon, Google, and Azure clouds, as well as, any other cloud platform based on OpenStack. Our package allows different scenarios of execution with different levels of sophistication, up to the one where a workflow can be executed using a cluster whose nodes come from different clouds. MC-GenomeKey also supports scenarios to exploit the spot instance model of Amazon in combination with the use of other cloud platforms to provide significant cost reduction. To the best of our knowledge, this is the first solution that optimizes the execution of the workflow using computational resources from different cloud providers. MC-GenomeKey provides an efficient multicloud based solution to detect and annotate mutations. The package can run in different commercial cloud platforms, which enables the user to seize the best offers. The package also provides a reliable means to make use of the low-cost spot instance model of Amazon, as it provides an efficient solution to the sudden termination of spot machines as a result of a sudden price increase. The package has a web-interface and it is available for free for academic use.

A software platform for the analysis of dermatology images

NASA Astrophysics Data System (ADS)

Vlassi, Maria; Mavraganis, Vlasios; Asvestas, Panteleimon

2017-11-01

The purpose of this paper is to present a software platform developed in Python programming environment that can be used for the processing and analysis of dermatology images. The platform provides the capability for reading a file that contains a dermatology image. The platform supports image formats such as Windows bitmaps, JPEG, JPEG2000, portable network graphics, TIFF. Furthermore, it provides suitable tools for selecting, either manually or automatically, a region of interest (ROI) on the image. The automated selection of a ROI includes filtering for smoothing the image and thresholding. The proposed software platform has a friendly and clear graphical user interface and could be a useful second-opinion tool to a dermatologist. Furthermore, it could be used to classify images including from other anatomical parts such as breast or lung, after proper re-training of the classification algorithms.

[Application of AOTF in spectral analysis. 1. Hardware and software designs for the self-constructed visible AOTF spectrophotometer].

PubMed

He, Jia-yao; Peng, Rong-fei; Zhang, Zhan-xia

2002-02-01

A self-constructed visible spectrophotometer using an acousto-optic tunable filter(AOTF) as a dispersing element is described. Two different AOTFs (one from The Institute for Silicate (Shanghai, China) and the other from Brimrose(USA)) are tested. The software written with visual C++ and operated on a Window98 platform is an applied program with dual database and multi-windows. Four independent windows, namely scanning, quantitative, calibration and result are incorporated. The Fourier self-deconvolution algorithm is also incorporated to improve the spectral resolution. The wavelengths are calibrated using the polynomial curve fitting method. The spectra and calibration curves of soluble aniline blue and phenol red are presented to show the feasibility of the constructed spectrophotometer.

To Mac or Not To Mac? One Apple Devotee's Excruciating Purchase Dilemma.

ERIC Educational Resources Information Center

Shenk, David

1998-01-01

Discusses the pros and cons of selecting Apple Macintosh computers versus a personal computer that runs the Windows platform. Graphical user interfaces, current and future support, and aesthetics are considered, as well as personal preferences. (LRW)

APEX 3: a multi-purpose test platform for auditory psychophysical experiments.

PubMed

Francart, Tom; van Wieringen, Astrid; Wouters, Jan

2008-07-30

APEX 3 is a software test platform for auditory behavioral experiments. It provides a generic means of setting up experiments without any programming. The supported output devices include sound cards and cochlear implants from Cochlear Corporation and Advanced Bionics Corporation. Many psychophysical procedures are provided and there is an interface to add custom procedures. Plug-in interfaces are provided for data filters and external controllers. APEX 3 is supported under Linux and Windows and is available free of charge.

Rugged sensor window materials for harsh environments

NASA Astrophysics Data System (ADS)

Bayya, Shyam; Villalobos, Guillermo; Kim, Woohong; Sanghera, Jasbinger; Hunt, Michael; Aggarwal, Ishwar D.

2014-09-01

There are several military or commercial systems operating in very harsh environments that require rugged windows. On some of these systems, windows become the single point of failure. These applications include sensor or imaging systems, high-energy laser weapons systems, submarine photonic masts, IR countermeasures and missiles. Based on the sea or land or air based platforms the window or dome on these systems must withstand wave slap, underwater or ground based explosions, or survive flight through heavy rain and sand storms while maintaining good optical transmission in the desired wavelength range. Some of these applications still use softer ZnS or fused silica windows because of lack of availability of rugged materials in shapes or sizes required. Sapphire, ALON and spinel are very rugged materials with significantly higher strengths compared to ZnS and fused silica. There have been recent developments in spinel, ALON and sapphire materials to fabricate in large sizes and conformal shapes. We have been developing spinel ceramics for several of these applications. We are also developing β-SiC as a transparent window material as it has higher hardness, strength, and toughness than sapphire, ALON and spinel. This paper gives a summary of our recent findings.

Polish Terms for "Blue" in the Perspective of Vantage Theory

ERIC Educational Resources Information Center

Stanulewicz, Danuta

2010-01-01

The Polish set of terms for blue includes, inter alia, the following adjectives: "niebieski" "blue", "blekitny" "(sky) blue", "granatowy" "navy blue", "lazurowy" "azure", "modry" "(intense) blue" and "siny" "(grey) violet-blue". The adjective "niebieski" is the basic term; however, it shares some of its functions with "blekitny", which is…

Authoritative Authoring: Software That Makes Multimedia Happen.

ERIC Educational Resources Information Center

Florio, Chris; Murie, Michael

1996-01-01

Compares seven mid- to high-end multimedia authoring software systems that combine graphics, sound, animation, video, and text for Windows and Macintosh platforms. A run-time project was created with each program using video, animation, graphics, sound, formatted text, hypertext, and buttons. (LRW)

Teaching individuals with intellectual disability to email across multiple device platforms.

PubMed

Cihak, David F; McMahon, Donald; Smith, Cate C; Wright, Rachel; Gibbons, Melinda M

2014-11-20

The purpose of this study was to examine the use of email by people with intellectual disability across multiple technological devices or platforms. Four individuals with intellectual disability participated in this study. Participants were taught how to access and send an email on a Windows desktop computer, laptop, and an iPad tablet device. Results indicated a functional relation. All participants acquired and generalized sending and receiving an email from multiple platforms. Conclusions are discussed about the importance of empowering people with intellectual disability by providing multiple means of expression, including the ability to communicate effectively using a variety of devices. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Benefits and Complexities of Operating Geographic Information Systems (GIS) in a High Performance Computing (HPC) Environment

NASA Astrophysics Data System (ADS)

Shute, J.; Carriere, L.; Duffy, D.; Hoy, E.; Peters, J.; Shen, Y.; Kirschbaum, D.

2017-12-01

The NASA Center for Climate Simulation (NCCS) at the Goddard Space Flight Center is building and maintaining an Enterprise GIS capability for its stakeholders, to include NASA scientists, industry partners, and the public. This platform is powered by three GIS subsystems operating in a highly-available, virtualized environment: 1) the Spatial Analytics Platform is the primary NCCS GIS and provides users discoverability of the vast DigitalGlobe/NGA raster assets within the NCCS environment; 2) the Disaster Mapping Platform provides mapping and analytics services to NASA's Disaster Response Group; and 3) the internal (Advanced Data Analytics Platform/ADAPT) enterprise GIS provides users with the full suite of Esri and open source GIS software applications and services. All systems benefit from NCCS's cutting edge infrastructure, to include an InfiniBand network for high speed data transfers; a mixed/heterogeneous environment featuring seamless sharing of information between Linux and Windows subsystems; and in-depth system monitoring and warning systems. Due to its co-location with the NCCS Discover High Performance Computing (HPC) environment and the Advanced Data Analytics Platform (ADAPT), the GIS platform has direct access to several large NCCS datasets including DigitalGlobe/NGA, Landsat, MERRA, and MERRA2. Additionally, the NCCS ArcGIS Desktop Windows virtual machines utilize existing NetCDF and OPeNDAP assets for visualization, modelling, and analysis - thus eliminating the need for data duplication. With the advent of this platform, Earth scientists have full access to vast data repositories and the industry-leading tools required for successful management and analysis of these multi-petabyte, global datasets. The full system architecture and integration with scientific datasets will be presented. Additionally, key applications and scientific analyses will be explained, to include the NASA Global Landslide Catalog (GLC) Reporter crowdsourcing application, the NASA GLC Viewer discovery and analysis tool, the DigitalGlobe/NGA Data Discovery Tool, the NASA Disaster Response Group Mapping Platform (https://maps.disasters.nasa.gov), and support for NASA's Arctic - Boreal Vulnerability Experiment (ABoVE).

Layer-by-layer assembled fluorescent probes in the second near-infrared window for systemic delivery and detection of ovarian cancer

PubMed Central

Dang, Xiangnan; Gu, Li; Qi, Jifa; Correa, Santiago; Zhang, Geran; Belcher, Angela M.; Hammond, Paula T.

2016-01-01

Fluorescence imaging in the second near-infrared window (NIR-II, 1,000–1,700 nm) features deep tissue penetration, reduced tissue scattering, and diminishing tissue autofluorescence. Here, NIR-II fluorescent probes, including down-conversion nanoparticles, quantum dots, single-walled carbon nanotubes, and organic dyes, are constructed into biocompatible nanoparticles using the layer-by-layer (LbL) platform due to its modular and versatile nature. The LbL platform has previously been demonstrated to enable incorporation of diagnostic agents, drugs, and nucleic acids such as siRNA while providing enhanced blood plasma half-life and tumor targeting. This work carries out head-to-head comparisons of currently available NIR-II probes with identical LbL coatings with regard to their biodistribution, pharmacokinetics, and toxicities. Overall, rare-earth-based down-conversion nanoparticles demonstrate optimal biological and optical performance and are evaluated as a diagnostic probe for high-grade serous ovarian cancer, typically diagnosed at late stage. Successful detection of orthotopic ovarian tumors is achieved by in vivo NIR-II imaging and confirmed by ex vivo microscopic imaging. Collectively, these results indicate that LbL-based NIR-II probes can serve as a promising theranostic platform to effectively and noninvasively monitor the progression and treatment of serous ovarian cancer. PMID:27114520

[Skyblue - the cyanometer of Horace-Bénédict de Saussure (1740 - 1799)].

PubMed

Breidbach, Olaf; Karliczek, André

2011-01-01

The cyanometer is a simply constructed measuring instrument that enables a determination of skyblue. It consists of a color-scale that is arranged circularly going in equal steps from white to blue (Prussian blue) and finally into black. According to its inventor--Horace-Bénédict de Saussure--the azure is determined by the amount of so called opaque vapors in the atmosphere associated with meteorological phenomena. As outlined by De Saussure, the blackness of the universe seen through an illuminated and blurred medium results in azure. Thereby his instrument offers a relative scale that is consistent with color theories of his time like those of Johann Wolfgang von Goethe. The description allows the construction of the scale without the employment of standardized color-prints. Instead he provides a clear report of the necessary procedures to produce such a scale. The accuracy of this description is tested and discussed employing the methods of experimental history of science. The reception of the cyanometer in the time about 1800 and its implications on color theories is discussed.

What Azure blues occur in Canada? A re-assessment of Celastrina Tutt species (Lepidoptera, Lycaenidae)

PubMed Central

Schmidt, B. Christian; Layberry, Ross A.

2016-01-01

Abstract The identity of Celastrina species in eastern Canada is reviewed based on larval host plants, phenology, adult phenotypes, mtDNA barcodes and re-assessment of published data. The status of the Cherry Gall Azure (Celastrina serotina Pavulaan & Wright) as a distinct species in Canada is not supported by any dataset, and is removed from the Canadian fauna. Previous records of this taxon are re-identified as Celastrina lucia (Kirby) and Celastrina neglecta (Edwards). Evidence is presented that both Celastrina lucia and Celastrina neglecta have a second, summer-flying generation in parts of Canada. The summer generation of Celastrina lucia has previously been misidentified as Celastrina neglecta, which differs in phenology, adult phenotype and larval hosts from summer Celastrina lucia. DNA barcodes are highly conserved among at least three North American Celastrina species, and provide no taxonomic information. Celastrina neglecta has a Canadian distribution restricted to southern Ontario, Manitoba, Saskatchewan and easternmost Alberta. The discovery of museum specimens of Celastrina ladon (Cramer) from southernmost Ontario represents a new species for the Canadian butterfly fauna, which is in need of conservation status assessment. PMID:27199600

Enhanced sonochemical degradation of azure B dye by the electroFenton process.

PubMed

Martínez, Susana Silva; Uribe, Edgar Velasco

2012-01-01

The degradation of azure B dye (C15H16ClN3S; AB) has been studied by Fenton, sonolysis and sono-electroFenton processes employing ultrasound at 23 kHz and the electrogeneration of H2O2 at the reticulated vitreous carbon electrode. It was found that the dye degradation followed apparent first-order kinetics in all the degradation processes tested. The rate constant was affected by both the pH of the solution and initial concentration of Fe2+, with the highest degradation obtained at pH between 2.6 and 3. The first-order rate constant decreased in the following order: sono-electroFenton>Fenton>sonolysis. The rate constant for AB degradation by sono-electroFenton is ∼10-fold that of sonolysis and ∼2-fold the one obtained by Fenton under silent conditions. The chemical oxygen demand was abated ∼68% and ∼85% by Fenton and sono-electroFenton respectively, achieving AB concentration removal over 90% with both processes. Copyright © 2011 Elsevier B.V. All rights reserved.

Potential electron mediators to extract electron energies of RBC glycolysis for prolonged in vivo functional lifetime of hemoglobin vesicles.

PubMed

Kettisen, Karin; Bülow, Leif; Sakai, Hiromi

2015-04-15

Developing a functional blood substitute as an alternative to donated blood for clinical use is believed to relieve present and future blood shortages, and to reduce the risks of infection and blood type mismatching. Hemoglobin vesicle (HbV) encapsulates a purified and concentrated human-derived Hb solution in a phospholipid vesicle (liposome). The in vivo safety and efficacy of HbV as a transfusion alternative have been clarified. Auto-oxidation of ferrous Hb in HbV gradually increases the level of ferric methemoglobin (metHb) and impairs the oxygen transport capabilities. The extension of the functional half-life of HbV has recently been proposed using an electron mediator, methylene blue (MB), which acts as a shuttle between red blood cells (RBC) and HbV. MB transfers electron energies of NAD(P)H, produced by RBC glycolysis, to metHb in HbV. Work presented here focuses on screening of 15 potential electron mediators, with appropriate redox potential and water solubility, for electron transfer from RBC to HbV. The results are assessed with regard to the chemical properties of the candidates. The compounds examined in this study were dimethyl methylene blue (DMB), methylene green, azure A, azure B, azure C, toluidine blue (TDB), thionin acetate, phenazine methosulfate, brilliant cresyl blue, cresyl violet, gallocyanine, toluylene blue, indigo carmine, indigotetrasulfonate, and MB. Six candidates were found to be unsuitable because of their insufficient diffusion across membranes, or overly high or nonexistent reactivity with relevant biomolecules. However, 9 displayed favorable metHb reduction. Among the suitable candidates, phenothiazines DMB and TDB exhibited effectiveness like MB did. In comparison to MB, they showed faster reduction by electron-donating NAD(P)H, coupled with showing a lower rate of reoxidation in the presence of molecular oxygen. Ascertaining the best electron mediator can provide a pathway for extending the lifetime and efficiency of potential blood substitutes.

SpiceyPy, a Python Wrapper for SPICE

NASA Astrophysics Data System (ADS)

Annex, A.

2017-06-01

SpiceyPy is an open source Python wrapper for the NAIF SPICE toolkit. It is available for macOS, Linux, and Windows platforms and for Python versions 2.7.x and 3.x as well as Anaconda. SpiceyPy can be installed by running: “pip install spiceypy.”

Business Simulation Games: Effective Teaching Tools or Window Dressing?

ERIC Educational Resources Information Center

Tanner, John R.; Stewart, Geoffrey; Totaro, Michael W.; Hargrave, Melissa

2012-01-01

Business simulations serve as learning platforms that stimulate the "gaming" interest of students, that provide a structured learning environment, and that should help manage the time resources of faculty. Simulations appear to provide a context where students feel learning can take place. However, faculty perception of simulation…

Classification of large-scale fundus image data sets: a cloud-computing framework.

PubMed

Roychowdhury, Sohini

2016-08-01

Large medical image data sets with high dimensionality require substantial amount of computation time for data creation and data processing. This paper presents a novel generalized method that finds optimal image-based feature sets that reduce computational time complexity while maximizing overall classification accuracy for detection of diabetic retinopathy (DR). First, region-based and pixel-based features are extracted from fundus images for classification of DR lesions and vessel-like structures. Next, feature ranking strategies are used to distinguish the optimal classification feature sets. DR lesion and vessel classification accuracies are computed using the boosted decision tree and decision forest classifiers in the Microsoft Azure Machine Learning Studio platform, respectively. For images from the DIARETDB1 data set, 40 of its highest-ranked features are used to classify four DR lesion types with an average classification accuracy of 90.1% in 792 seconds. Also, for classification of red lesion regions and hemorrhages from microaneurysms, accuracies of 85% and 72% are observed, respectively. For images from STARE data set, 40 high-ranked features can classify minor blood vessels with an accuracy of 83.5% in 326 seconds. Such cloud-based fundus image analysis systems can significantly enhance the borderline classification performances in automated screening systems.

New Collaborative Strategies for Bringing the Geosciences to Students, Teachers, and the Public: Progress and Opportunities from the National Earth Science Teachers Association and Windows to the Universe

NASA Astrophysics Data System (ADS)

Johnson, R. M.; Herrold, A.; Holzer, M. A.; Passow, M. J.

2010-12-01

The geoscience research and education community is interested in developing scalable and effective user-friendly strategies for reaching the public, students and educators with information about the Earth and space sciences. Based on experience developed over the past decade with education and outreach programs seeking to reach these populations, there is a growing consensus that this will be best achieved through collaboration, leveraging the resources and networks already in existence. While it is clear that gifted researchers and developers can create wonderful online educational resources, many programs have been stymied by the difficulty of attracting an audience to these resources. The National Earth Science Teachers Association (NESTA) has undertaken an exciting new project, with support from the William and Flora Hewlett Foundation, that provides a new platform for the geoscience education and research community to share their research, resources, programs, products and services with a wider audience. In April 2010, the Windows to the Universe project (http://windows2universe.org) moved from the University Corporation for Atmospheric Research to NESTA. Windows to the Universe, which started in 1995 at the University of Michigan, is one of the most popular Earth and space science education websites globally, with over 16 million visits annually. The objective of this move is to develop a suite of new opportunities and capabilities on the website that will allow it become a sustainable education and outreach platform for the geoscience research and education community hosting open educational resources. This presentation will provide an update on our progress, highlighting our new strategies, synergies with community needs, and opportunities for collaboration.

Analysis of matters associated with the transferring of object-oriented applications to platform .Net using C# programming language

NASA Astrophysics Data System (ADS)

Sarsimbayeva, S. M.; Kospanova, K. K.

2015-11-01

The article provides the discussion of matters associated with the problems of transferring of object-oriented Windows applications from C++ programming language to .Net platform using C# programming language. C++ has always been considered to be the best language for the software development, but the implicit mistakes that come along with the tool may lead to infinite memory leaks and other errors. The platform .Net and the C#, made by Microsoft, are the solutions to the issues mentioned above. The world economy and production are highly demanding applications developed by C++, but the new language with its stability and transferability to .Net will bring many advantages. An example can be presented using the applications that imitate the work of queuing systems. Authors solved the problem of transferring of an application, imitating seaport works, from C++ to the platform .Net using C# in the scope of Visual Studio.

The GeoCitizen-approach: community-based spatial planning – an Ecuadorian case study

PubMed Central

Atzmanstorfer, Karl; Resl, Richard; Eitzinger, Anton; Izurieta, Xiomara

2014-01-01

Over the last years, geospatial web platforms, social media, and volunteered geographic information (VGI) have opened a window of opportunity for traditional Public Participatory GIS (PPGIS) to usher in a new era. Taking advantage of these technological achievements, this paper presents a new approach for a citizen-orientated framework of spatial planning that aims at integrating participatory community work into existing decision-making structures. One major cornerstone of the presented approach is the application of a social geoweb platform (the GeoCitizen platform) that combines geo-web technologies and social media in one single tool allowing citizens to collaboratively report observations, discuss ideas, solve, and monitor problems in their living environment at a local level. This paper gives an account of an ongoing participatory land-zoning process in the Capital District of Quito, Ecuador, where the GeoCitizen platform is applied in a long-term study. PMID:27019644

Classifying proteins into functional groups based on all-versus-all BLAST of 10 million proteins.

PubMed

Kolker, Natali; Higdon, Roger; Broomall, William; Stanberry, Larissa; Welch, Dean; Lu, Wei; Haynes, Winston; Barga, Roger; Kolker, Eugene

2011-01-01

To address the monumental challenge of assigning function to millions of sequenced proteins, we completed the first of a kind all-versus-all sequence alignments using BLAST for 9.9 million proteins in the UniRef100 database. Microsoft Windows Azure produced over 3 billion filtered records in 6 days using 475 eight-core virtual machines. Protein classification into functional groups was then performed using Hive and custom jars implemented on top of Apache Hadoop utilizing the MapReduce paradigm. First, using the Clusters of Orthologous Genes (COG) database, a length normalized bit score (LNBS) was determined to be the best similarity measure for classification of proteins. LNBS achieved sensitivity and specificity of 98% each. Second, out of 5.1 million bacterial proteins, about two-thirds were assigned to significantly extended COG groups, encompassing 30 times more assigned proteins. Third, the remaining proteins were classified into protein functional groups using an innovative implementation of a single-linkage algorithm on an in-house Hadoop compute cluster. This implementation significantly reduces the run time for nonindexed queries and optimizes efficient clustering on a large scale. The performance was also verified on Amazon Elastic MapReduce. This clustering assigned nearly 2 million proteins to approximately half a million different functional groups. A similar approach was applied to classify 2.8 million eukaryotic sequences resulting in over 1 million proteins being assign to existing KOG groups and the remainder clustered into 100,000 functional groups.

Ultrasound window-modulated compounding Nakagami imaging: Resolution improvement and computational acceleration for liver characterization.

PubMed

Ma, Hsiang-Yang; Lin, Ying-Hsiu; Wang, Chiao-Yin; Chen, Chiung-Nien; Ho, Ming-Chih; Tsui, Po-Hsiang

2016-08-01

Ultrasound Nakagami imaging is an attractive method for visualizing changes in envelope statistics. Window-modulated compounding (WMC) Nakagami imaging was reported to improve image smoothness. The sliding window technique is typically used for constructing ultrasound parametric and Nakagami images. Using a large window overlap ratio may improve the WMC Nakagami image resolution but reduces computational efficiency. Therefore, the objectives of this study include: (i) exploring the effects of the window overlap ratio on the resolution and smoothness of WMC Nakagami images; (ii) proposing a fast algorithm that is based on the convolution operator (FACO) to accelerate WMC Nakagami imaging. Computer simulations and preliminary clinical tests on liver fibrosis samples (n=48) were performed to validate the FACO-based WMC Nakagami imaging. The results demonstrated that the width of the autocorrelation function and the parameter distribution of the WMC Nakagami image reduce with the increase in the window overlap ratio. One-pixel shifting (i.e., sliding the window on the image data in steps of one pixel for parametric imaging) as the maximum overlap ratio significantly improves the WMC Nakagami image quality. Concurrently, the proposed FACO method combined with a computational platform that optimizes the matrix computation can accelerate WMC Nakagami imaging, allowing the detection of liver fibrosis-induced changes in envelope statistics. FACO-accelerated WMC Nakagami imaging is a new-generation Nakagami imaging technique with an improved image quality and fast computation. Copyright © 2016 Elsevier B.V. All rights reserved.

Design optimization of highly asymmetrical layouts by 2D contour metrology

NASA Astrophysics Data System (ADS)

Hu, C. M.; Lo, Fred; Yang, Elvis; Yang, T. H.; Chen, K. C.

2018-03-01

As design pitch shrinks to the resolution limit of up-to-date optical lithography technology, the Critical Dimension (CD) variation tolerance has been dramatically decreased for ensuring the functionality of device. One of critical challenges associates with the narrower CD tolerance for whole chip area is the proximity effect control on asymmetrical layout environments. To fulfill the tight CD control of complex features, the Critical Dimension Scanning Electron Microscope (CD-SEM) based measurement results for qualifying process window and establishing the Optical Proximity Correction (OPC) model become insufficient, thus 2D contour extraction technique [1-5] has been an increasingly important approach for complementing the insufficiencies of traditional CD measurement algorithm. To alleviate the long cycle time and high cost penalties for product verification, manufacturing requirements are better to be well handled at design stage to improve the quality and yield of ICs. In this work, in-house 2D contour extraction platform was established for layout design optimization of 39nm half-pitch Self-Aligned Double Patterning (SADP) process layer. Combining with the adoption of Process Variation Band Index (PVBI), the contour extraction platform enables layout optimization speedup as comparing to traditional methods. The capabilities of identifying and handling lithography hotspots in complex layout environments of 2D contour extraction platform allow process window aware layout optimization to meet the manufacturing requirements.

Integrated Approach to User Account Management

NASA Technical Reports Server (NTRS)

Kesselman, Glenn; Smith, William

2007-01-01

IT environments consist of both Windows and other platforms. Providing user account management for this model has become increasingly diffi cult. If Microsoft#s Active Directory could be enhanced to extend a W indows identity for authentication services for Unix, Linux, Java and Macintosh systems, then an integrated approach to user account manag ement could be realized.

9. GENERAL INTERIOR VIEW OF BEEF KILLING FLOOR; LOOKING SOUTHEAST; ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. GENERAL INTERIOR VIEW OF BEEF KILLING FLOOR; LOOKING SOUTHEAST; PLATFORMS IN FOREGROUND WERE USED BY SPLITTERS, TRIMMERS AND GOVERNMENT INSPECTORS; SKINNING TABLE RAN ALONG THE WINDOWS NEAR THE CENTER OF THE PHOTO - Rath Packing Company, Beef Killing Building, Sycamore Street between Elm & Eighteenth Streets, Waterloo, Black Hawk County, IA

Scientific Programming Using Java and C: A Remote Sensing Example

NASA Technical Reports Server (NTRS)

Prados, Donald; Johnson, Michael; Mohamed, Mohamed A.; Cao, Chang-Yong; Gasser, Jerry; Powell, Don; McGregor, Lloyd

1999-01-01

This paper presents results of a project to port code for processing remotely sensed data from the UNIX environment to Windows. Factors considered during this process include time schedule, cost, resource availability, reuse of existing code, rapid interface development, ease of integration, and platform independence. The approach selected for this project used both Java and C. By using Java for the graphical user interface and C for the domain model, the strengths of both languages were utilized and the resulting code can easily be ported to other platforms. The advantages of this approach are discussed in this paper.

Oblique view of the Orbiter Discovery from an elevated platform ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Oblique view of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the Forward Reaction Control System (RCS) Module from the forward section and the Orbiter Maneuvering System (OMS)/RCS pods from the aft section have been removed. Ground support equipment called Strongbacks are attached to the payload bay doors and the Flight Deck windows have been covered by ground support equipment. Also note the scale figure standing by the Orbiter. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Multimodal sensing strategies for detecting transparent barriers indoors from a mobile platform

NASA Astrophysics Data System (ADS)

Acevedo, Isaiah; Kleine, R. Kaleb; Kraus, Dustan; Mascareñas, David

2015-04-01

There is currently an interest in developing mobile sensing platforms that fly indoors. The primary goal for these platforms is to be able to successfully navigate a building under various lighting and environmental conditions. There are numerous research challenges associated with this goal, one of which is the platform's ability to detect and identify the presence of transparent barriers. Transparent barriers could include windows, glass partitions, or skylights. For example, in order to successfully navigate inside of a structure, these platforms will need to sense if a space contains a transparent barrier and whether or not this space can be traversed. This project's focus has been developing a multimodal sensing system that can successfully identify such transparent barriers under various lighting conditions while aboard a mobile platform. Along with detecting transparent barriers, this sensing platform is capable of distinguishing between reflective, opaque, and transparent barriers. It will be critical for this system to be able to identify transparent barriers in real-time in order for the navigation system to maneuver accordingly. The properties associated with the interaction between various frequencies of light and transparent materials were one of the techniques leveraged to solve this problem.

75 FR 44291 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-28

... available, freeze- dried marine bacterium, Vibrio fisher, NRRL B-11177, for experimental use at the McMurdo Station Crary Science and Engineering Center (CSEC). This bacterium is used as one of the reagents for the Microtox toxicity analyzer, Azur Environmental model 500, 0073486. The bacterium are used with a...

Increasing the Weaponization of Space: A Prescription for Further Progress

DTIC Science & Technology

1998-04-01

130 APPENDIX C : SPACE WEAPON PHENOMENOLOGIES...level of research and development (R& D ) to occur. Based on information from a prudent R& D effort, including realistic test results, DOD will be able...2B First European Space Research Organization (ESRO) satellite 8 Nov 1969 Azur First West German satellite (on U.S. launcher) 24 Apr 1970 SKW-1 (DFH1

A Computer Simulation Using Spreadsheets for Learning Concept of Steady-State Equilibrium

ERIC Educational Resources Information Center

Sharda, Vandana; Sastri, O. S. K. S.; Bhardwaj, Jyoti; Jha, Arbind K.

2016-01-01

In this paper, we present a simple spreadsheet based simulation activity that can be performed by students at the undergraduate level. This simulation is implemented in free open source software (FOSS) LibreOffice Calc, which is available for both Windows and Linux platform. This activity aims at building the probability distribution for the…

Mindfulness and Compassion Training in Adolescence: A Developmental Contemplative Science Perspective

ERIC Educational Resources Information Center

Roeser, Robert W.; Pinela, Cristi

2014-01-01

Adolescence is a developmental period of risk, as well as a window of opportunity for cultivating positive development and thriving. It is characterized by simultaneous changes in the brain, body, mind, and social domains that offer a platform for building new skills and habits. This chapter discusses the role that secular forms of mindfulness and…

Allinea Parallel Profiling and Debugging Tools on the Peregrine System |

Science.gov Websites

client for your platform. (Mac/Windows/Linux) Configuration to connect to Peregrine: Open the Allinea view it # directly through x11 forwarding just type 'map', # it will open a GUI. $ map # to profile an enable x-forwarding when connecting to # Peregrine. $ map # This will open the GUI Debugging using

Comparison of LASSO and GPS time transfers

NASA Technical Reports Server (NTRS)

Lewandowski, W.; Petit, G.; Baumont, F.; Fridelance, P.; Gaignebet, J.; Grudler, P.; Veillet, C.; Wiant, J.; Klepczynski, W. J.

1994-01-01

The LASSO is a technique which should allow the comparison of remote atomic clocks with sub-nanosecond precision and accuracy. The first successful time transfer using LASSO has been carried out between the Observatoire de la Cote d'Azur in France and the McDonald Observatory in Texas, United States. This paper presents a preliminary comparison of LASSO time transfer with GPS common-view time transfer.

Molmil: a molecular viewer for the PDB and beyond.

PubMed

Bekker, Gert-Jan; Nakamura, Haruki; Kinjo, Akira R

2016-01-01

We have developed a new platform-independent web-based molecular viewer using JavaScript and WebGL. The molecular viewer, Molmil, has been integrated into several services offered by Protein Data Bank Japan and can be easily extended with new functionality by third party developers. Furthermore, the viewer can be used to load files in various formats from the user's local hard drive without uploading the data to a server. Molmil is available for all platforms supporting WebGL (e.g. Windows, Linux, iOS, Android) from http://gjbekker.github.io/molmil/. The source code is available at http://github.com/gjbekker/molmil under the LGPLv3 licence.

Supercontinuum optimization for dual-soliton based light sources using genetic algorithms in a grid platform.

PubMed

Arteaga-Sierra, F R; Milián, C; Torres-Gómez, I; Torres-Cisneros, M; Moltó, G; Ferrando, A

2014-09-22

We present a numerical strategy to design fiber based dual pulse light sources exhibiting two predefined spectral peaks in the anomalous group velocity dispersion regime. The frequency conversion is based on the soliton fission and soliton self-frequency shift occurring during supercontinuum generation. The optimization process is carried out by a genetic algorithm that provides the optimum input pulse parameters: wavelength, temporal width and peak power. This algorithm is implemented in a Grid platform in order to take advantage of distributed computing. These results are useful for optical coherence tomography applications where bell-shaped pulses located in the second near-infrared window are needed.

The designing and implementation of PE teaching information resource database based on broadband network

NASA Astrophysics Data System (ADS)

Wang, Jian

2017-01-01

In order to change traditional PE teaching mode and realize the interconnection, interworking and sharing of PE teaching resources, a distance PE teaching platform based on broadband network is designed and PE teaching information resource database is set up. The designing of PE teaching information resource database takes Windows NT 4/2000Server as operating system platform, Microsoft SQL Server 7.0 as RDBMS, and takes NAS technology for data storage and flow technology for video service. The analysis of system designing and implementation shows that the dynamic PE teaching information resource sharing platform based on Web Service can realize loose coupling collaboration, realize dynamic integration and active integration and has good integration, openness and encapsulation. The distance PE teaching platform based on Web Service and the design scheme of PE teaching information resource database can effectively solve and realize the interconnection, interworking and sharing of PE teaching resources and adapt to the informatization development demands of PE teaching.

Visualizing DOM super-spectrum covariance in vanKrevelen space

NASA Astrophysics Data System (ADS)

Fatland, D. R.; Kalawe, J.; Stubbins, A.; Spencer, R. G.; Sleighter, R. L.; Abdulla, H. A.; Dittmar, T.

2011-12-01

We investigate the fate of terrigenous organic matter, DOM exported to the coastal marine environ. Many methods (fluor., FT-ICR-MS, NMR, 13C, lignin, etc) help characterize this DOM. We define a 'super spectrum' as amalgamation of analyses to a data stack and we search for physically significant patterns therein beginning with covariance across 31 samples from six circum-Arctic rivers: The Ob, Kolyma, Mackenzie, Yukon, Lena, and Yenisey sampled five times throughout the year. A vanKrevelen diagram is convenient to view distributions of molecules provided by Fourier Transform Ion Cyclotron Resonance Mass Spectometry (FT-ICR-MS). We augment this distribution space in the vertical dimension, for example to show peak height, molecular mass, principle component weighting or covariance. We use Worldwide Telescope, a virtual globe with strong data support from Microsoft Research to explore covariance results along 3+ dimensions (adding brightness, color and a parameter slide). The results show interesting covariance e.g. between molecules and PARAFAC peaks, a step towards fluorophore and cohort identification in the terrigenous DOM spectrum. Given the geoscience explosion in data volume and data complexity we feel these results should survive beyond the end point of a journal article. We are building a cloud-based Library on the Microsoft Azure platform to support this and subsequent analyses to enable data and methods to carry over and benefit other research groups and objectives.

Seismic Canvas: Evolution as a Data Exploration and Analysis Tool

NASA Astrophysics Data System (ADS)

Kroeger, G. C.

2015-12-01

SeismicCanvas, originally developed as a prototype interactive waveform display and printing application for educational use has evolved to include significant data exploration and analysis functionality. The most recent version supports data import from a variety of standard file formats including SAC and mini-SEED, as well as search and download capabilities via IRIS/FDSN Web Services. Data processing tools now include removal of means and trends, interactive windowing, filtering, smoothing, tapering, resampling. Waveforms can be displayed in a free-form canvas or as a record section based on angular or great circle distance, azimuth or back azimuth. Integrated tau-p code allows the calculation and display of theoretical phase arrivals from a variety of radial Earth models. Waveforms can be aligned by absolute time, event time, picked or theoretical arrival times and can be stacked after alignment. Interactive measurements include means, amplitudes, time delays, ray parameters and apparent velocities. Interactive picking of an arbitrary list of seismic phases is supported. Bode plots of amplitude and phase spectra and spectrograms can be created from multiple seismograms or selected windows of seismograms. Direct printing is implemented on all supported platforms along with output of high-resolution pdf files. With these added capabilities, the application is now being used as a data exploration tool for research. Coded in C++ and using the cross-platform Qt framework, the most recent version is available as a 64-bit application for Windows 7-10, Mac OS X 10.6-10.11, and most distributions of Linux, and a 32-bit version for Windows XP and 7. With the latest improvements and refactoring of trace display classes, the 64-bit versions have been tested with over 250 million samples and remain responsive in interactive operations. The source code is available under a LPGLv3 license and both source and executables are available through the IRIS SeisCode repository.

Characterization of AFB sapphire single crystal composites for infrared window application

NASA Astrophysics Data System (ADS)

Lee, H.-C.; Meissner, H. E.

2007-04-01

Next generation weapons platforms may require 30" x 30" sapphire windows. Since these sizes exceed what can be manufactured directly, a concept is proposed and experimental data are furnished in this report on the viability of increasing the window dimensions by Adhesive-Free-Bonding (AFB®) of smaller starting components by their edges. The bonding scheme has been evaluated for single crystal sapphire but is expected to also work equally well for other IR window materials. The bonding mechanism is explained with Van der Waals theory of attractive forces and confirmed experimentally by applying the bending plate theory. The gap at the interface between two components is deduced from the measured roughness of the polished surfaces that are brought into optical contact and subsequently heat-treated, and is estimated to be about 2 Å rms. Stress relief at AFB® interfaces has been established. Experimental data of flexural strength determined by four-point bending at room temperature is reported. The data indicates that AFB® composite specimens and equivalently prepared blank samples fracture at statistically same loads under standardized testing conditions. Failure of composites has not been observed at the interface and only at random flaws that are a result of sample preparation.

Bird Vision System

NASA Technical Reports Server (NTRS)

2008-01-01

The Bird Vision system is a multicamera photogrammerty software application that runs on a Microsoft Windows XP platform and was developed at Kennedy Space Center by ASRC Aerospace. This software system collects data about the locations of birds within a volume centered on the Space Shuttle and transmits it in real time to the laptop computer of a test director in the Launch Control Center (LCC) Firing Room.

Virtual network computing: cross-platform remote display and collaboration software.

PubMed

Konerding, D E

1999-04-01

VNC (Virtual Network Computing) is a computer program written to address the problem of cross-platform remote desktop/application display. VNC uses a client/server model in which an image of the desktop of the server is transmitted to the client and displayed. The client collects mouse and keyboard input from the user and transmits them back to the server. The VNC client and server can run on Windows 95/98/NT, MacOS, and Unix (including Linux) operating systems. VNC is multi-user on Unix machines (any number of servers can be run are unrelated to the primary display of the computer), while it is effectively single-user on Macintosh and Windows machines (only one server can be run, displaying the contents of the primary display of the server). The VNC servers can be configured to allow more than one client to connect at one time, effectively allowing collaboration through the shared desktop. I describe the function of VNC, provide details of installation, describe how it achieves its goal, and evaluate the use of VNC for molecular modelling. VNC is an extremely useful tool for collaboration, instruction, software development, and debugging of graphical programs with remote users.

Popularity and Novelty Dynamics in Evolving Networks.

PubMed

Abbas, Khushnood; Shang, Mingsheng; Abbasi, Alireza; Luo, Xin; Xu, Jian Jun; Zhang, Yu-Xia

2018-04-20

Network science plays a big role in the representation of real-world phenomena such as user-item bipartite networks presented in e-commerce or social media platforms. It provides researchers with tools and techniques to solve complex real-world problems. Identifying and predicting future popularity and importance of items in e-commerce or social media platform is a challenging task. Some items gain popularity repeatedly over time while some become popular and novel only once. This work aims to identify the key-factors: popularity and novelty. To do so, we consider two types of novelty predictions: items appearing in the popular ranking list for the first time; and items which were not in the popular list in the past time window, but might have been popular before the recent past time window. In order to identify the popular items, a careful consideration of macro-level analysis is needed. In this work we propose a model, which exploits item level information over a span of time to rank the importance of the item. We considered ageing or decay effect along with the recent link-gain of the items. We test our proposed model on four various real-world datasets using four information retrieval based metrics.

Tunable Rare Earth fcu-MOF Platform: Access to Adsorption Kinetics Driven Gas/Vapor Separations via Pore Size Contraction.

PubMed

Xue, Dong-Xu; Belmabkhout, Youssef; Shekhah, Osama; Jiang, Hao; Adil, Karim; Cairns, Amy J; Eddaoudi, Mohamed

2015-04-22

Reticular chemistry approach was successfully employed to deliberately construct new rare-earth (RE, i.e., Eu(3+), Tb(3+), and Y(3+)) fcu metal-organic frameworks (MOFs) with restricted window apertures. Controlled and selective access to the resultant contracted fcu-MOF pores permits the achievement of the requisite sorbate cutoff, ideal for selective adsorption kinetics based separation and/or molecular sieving of gases and vapors. Predetermined reaction conditions that permitted the formation in situ of the 12-connected RE hexanuclear molecular building block (MBB) and the establishment of the first RE-fcu-MOF platform, especially in the presence of 2-fluorobenzoic acid (2-FBA) as a modulator and a structure directing agent, were used to synthesize isostructural RE-1,4-NDC-fcu-MOFs based on a relatively bulkier 2-connected bridging ligand, namely 1,4-naphthalenedicarboxylate (1,4-NDC). The subsequent RE-1,4-NDC-fcu-MOF structural features, contracted windows/pores and high concentration of open metal sites combined with exceptional hydrothermal and chemical stabilities, yielded notable gas/solvent separation properties, driven mostly by adsorption kinetics as exemplified in this work for n-butane/methane, butanol/methanol, and butanol/water pair systems.

Adobe acrobat: an alternative electronic teaching file construction methodology independent of HTML restrictions.

PubMed

Katzman, G L

2001-03-01

The goal of the project was to create a method by which an in-house digital teaching file could be constructed that was simple, inexpensive, independent of hypertext markup language (HTML) restrictions, and appears identical on multiple platforms. To accomplish this, Microsoft PowerPoint and Adobe Acrobat were used in succession to assemble digital teaching files in the Acrobat portable document file format. They were then verified to appear identically on computers running Windows, Macintosh Operating Systems (OS), and the Silicon Graphics Unix-based OS as either a free-standing file using Acrobat Reader software or from within a browser window using the Acrobat browser plug-in. This latter display method yields a file viewed through a browser window, yet remains independent of underlying HTML restrictions, which may confer an advantage over simple HTML teaching file construction. Thus, a hybrid of HTML-distributed Adobe Acrobat generated WWW documents may be a viable alternative for digital teaching file construction and distribution.

Door and window image-based measurement using a mobile device

NASA Astrophysics Data System (ADS)

Ma, Guangyao; Janakaraj, Manishankar; Agam, Gady

2015-03-01

We present a system for door and window image-based measurement using an Android mobile device. In this system a user takes an image of a door or window that needs to be measured and using interaction measures specific dimensions of the object. The existing object is removed from the image and a 3D model of a replacement is rendered onto the image. The visualization provides a 3D model with which the user can interact. When tested on a mobile Android platform with an 8MP camera we obtain an average measurement error of roughly 0.5%. This error rate is stable across a range of view angles, distances from the object, and image resolutions. The main advantages of our mobile device application for image measurement include measuring objects for which physical access is not readily available, documenting in a precise manner the locations in the scene where the measurements were taken, and visualizing a new object with custom selections inside the original view.

Flexible thermochromic window based on hybridized VO2/graphene.

PubMed

Kim, Hyeongkeun; Kim, Yena; Kim, Keun Soo; Jeong, Hu Young; Jang, A-Rang; Han, Seung Ho; Yoon, Dae Ho; Suh, Kwang S; Shin, Hyeon Suk; Kim, TaeYoung; Yang, Woo Seok

2013-07-23

Large-scale integration of vanadium dioxide (VO2) on mechanically flexible substrates is critical to the realization of flexible smart window films that can respond to environmental temperatures to modulate light transmittance. Until now, the formation of highly crystalline and stoichiometric VO2 on flexible substrate has not been demonstrated due to the high-temperature condition for VO2 growth. Here, we demonstrate a VO2-based thermochromic film with unprecedented mechanical flexibility by employing graphene as a versatile platform for VO2. The graphene effectively functions as an atomically thin, flexible, yet robust support which enables the formation of stoichiometric VO2 crystals with temperature-driven phase transition characteristics. The graphene-supported VO2 was capable of being transferred to a plastic substrate, forming a new type of flexible thermochromic film. The flexible VO2 films were then integrated into the mock-up house, exhibiting its efficient operation to reduce the in-house temperature under infrared irradiation. These results provide important progress for the fabrication of flexible thermochromic films for energy-saving windows.

Model-Driven Engineering: Automatic Code Generation and Beyond

DTIC Science & Technology

2015-03-01

and Weblogic as well as cloud environments such as Mi- crosoft Azure and Amazon Web Services®. Finally, while the generated code has dependencies on...code generation in the context of the full system lifecycle from development to sustainment. Acquisition programs in govern- ment or large commercial...Acquirers are concerned with the full system lifecycle, and they need confidence that the development methods will enable the system to meet the functional

Development of Strategic Air Command, 1946 - 1976

DTIC Science & Technology

1976-03-01

flashes red. Azure , two clouds proper, one issuing from sinister chief and one issuing from dexter base, a cubit arm in armor in bend, issuing...security reasons, no statistics have been Included for those types of recon- naissance aircraft currently assigned. The text was prepared by Mr. J. C...Hopkins who was aided by Mr. Sheldon A. Goldberg, Command Archivist, who critically reviewed the text and selected the photographs. Special

An Evidence-based Forensic Taxonomy of Windows Phone Dating Apps.

PubMed

Cahyani, Niken Dwi Wahyu; Choo, Kim-Kwang Raymond; Ab Rahman, Nurul Hidayah; Ashman, Helen

2018-05-21

Advances in technologies including development of smartphone features have contributed to the growth of mobile applications, including dating apps. However, online dating services can be misused. To support law enforcement investigations, a forensic taxonomy that provides a systematic classification of forensic artifacts from Windows Phone 8 (WP8) dating apps is presented in this study. The taxonomy has three categories, namely: Apps Categories, Artifacts Categories, and Data Partition Categories. This taxonomy is built based on the findings from a case study of 28 mobile dating apps, using mobile forensic tools. The dating app taxonomy can be used to inform future studies of dating and related apps, such as those from Android and iOS platforms. © 2018 American Academy of Forensic Sciences.

Spotlight-8 Image Analysis Software

NASA Technical Reports Server (NTRS)

Klimek, Robert; Wright, Ted

2006-01-01

Spotlight is a cross-platform GUI-based software package designed to perform image analysis on sequences of images generated by combustion and fluid physics experiments run in a microgravity environment. Spotlight can perform analysis on a single image in an interactive mode or perform analysis on a sequence of images in an automated fashion. Image processing operations can be employed to enhance the image before various statistics and measurement operations are performed. An arbitrarily large number of objects can be analyzed simultaneously with independent areas of interest. Spotlight saves results in a text file that can be imported into other programs for graphing or further analysis. Spotlight can be run on Microsoft Windows, Linux, and Apple OS X platforms.

VisIVO: A Tool for the Virtual Observatory and Grid Environment

NASA Astrophysics Data System (ADS)

Becciani, U.; Comparato, M.; Costa, A.; Larsson, B.; Gheller, C.; Pasian, F.; Smareglia, R.

2007-10-01

We present the new features of VisIVO, software for the visualization and analysis of astrophysical data which can be retrieved from the Virtual Observatory framework and used for cosmological simulations running both on Windows and GNU/Linux platforms. VisIVO is VO standards compliant and supports the most important astronomical data formats such as FITS, HDF5 and VOTables. It is free software and can be downloaded from the web site http://visivo.cineca.it. VisIVO can interoperate with other astronomical VO compliant tools through PLASTIC (PLatform for AStronomical Tool InterConnection). This feature allows VisIVO to share data with many other astronomical packages to further analyze the loaded data.

Current and future bioanalytical approaches for stroke assessment.

PubMed

Pullagurla, Swathi R; Baird, Alison E; Adamski, Mateusz G; Soper, Steven A

2015-01-01

Efforts are underway to develop novel platforms for stroke diagnosis to meet the criteria for effective treatment within the narrow time window mandated by the FDA-approved therapeutic (<3 h). Blood-based biomarkers could be used for rapid stroke diagnosis and coupled with new analytical tools, could serve as an attractive platform for managing stroke-related diseases. In this review, we will discuss the physiological processes associated with stroke and current diagnostic tools as well as their associated shortcomings. We will then review information on blood-based biomarkers and various detection technologies. In particular, point of care testing that permits small blood volumes required for the analysis and rapid turn-around time measurements of multiple markers will be presented.

A Topographic Field Trip of Washington, D.C. - A Cartographic Multimedia Application

USGS Publications Warehouse

,

1999-01-01

The U.S. Geological Survey (USGS) has produced ?A Topographic Field Trip of Washington, D.C.,' a multimedia CD-ROM that uses topographic maps to tour Washington, D.C. Although designed for the middle school grade level, it can also be used to teach introductory topographic map reading skills to any level. Two versions of ?A Topographic Field Trip of Washington, D.C.,? are available. The first version, for Macintosh? systems only, was developed and produced as a prototype with educational resources funds and is available free of charge. The second version, for dual platforms, Macintosh?, and Windows? systems, is a sales item. The dual platform version contains improvements in content and navigational capabilities.

Implementing Information Assurance - Beyond Process

DTIC Science & Technology

2009-01-01

disabled or properly configured. Tools and scripts are available to expedite the configuration process on some platforms, For example, approved Windows...in the System Security Plan (SSP) or Information Security Plan (lSP). Any PPSs not required for operation by the system must be disabled , This...Services must be disabled , Implementing an 1M capability within the boundary carries many policy and documentation requirements. Usemame and passwords

ISS Has an Attitude! Determining ISS Attitude at the ISS Window Observational Research Facility (WORF) Using Landmarks

NASA Technical Reports Server (NTRS)

Runco, Susan K.; Pickard,Henry; Kowtha, Vijayanand; Jackson, Dan

2011-01-01

Universities and secondary schools can help solve a real issue for remote sensing from the ISS WORF through hands-on engineering and activities. Remote sensing technology is providing scientists with higher resolution, higher sensitivity sensors. Where is it pointing? - To take full advantage of these improved sensors, space platforms must provide commensurate improvements in attitude determination

2D and 3D Method of Characteristic Tools for Complex Nozzle Development

NASA Technical Reports Server (NTRS)

Rice, Tharen

2003-01-01

This report details the development of a 2D and 3D Method of Characteristic (MOC) tool for the design of complex nozzle geometries. These tools are GUI driven and can be run on most Windows-based platforms. The report provides a user's manual for these tools as well as explains the mathematical algorithms used in the MOC solutions.

Toxicity of Tolyltriazole to Gram-Positive Coccus Microorganisms

DTIC Science & Technology

2000-03-01

Bausmith and Neufield 459). The second general category is the SAE Type II ADAF, which is a Type I ADAF with the addition of synthetic polymers...Act of 1972 ( Bausmith and Neufield 459, Gallagher 1995:109). The FAA and EPA requirements concerning ADAFs are often in conflict; as the FAA...AZUR Environmental. "Microtox Rapid Toxicity Testing System". http://www.azurenv.com/mtox.htm. October 1999. 3. Bausmith , David S. and Ronald D

Aeronautical Knowledge (Selected Articles),

DTIC Science & Technology

1983-04-11

distribution unlimited. THIS TRANSLATION IS A RENDITION OF THE ORIGI. NAL FOREIGN TEXT WITH4OUT ANY ANALYTICAL ORt EDITORIAL COMMENT. STATEMENTS ORt THEORIES...An operator busily touched a row of milky white switches on a computer . Groups of vermilion number codes incessantly flickered on a light blue display...On a Surface Observation Ship in the Launch Sea Area Blue sky and azure sea with light breeze and small waves were scenes of the launch sea area. In

The Development of Strategic Air Command, 1946-1976

DTIC Science & Technology

1976-03-21

branch green, and three lightning flashes red. SHIELD Azure , two clouds proper, one issuing from sinister chief and one issuing from dexter base, a...Financial Status, since 1958. For security reasons, no statistics have been included for those types of recon- naissance aircraft currently a ned. The text ...was prepared by . J C.)Hop~ns who was aided by Mr. Sheldon A. Goldberg, Command Archivist, w o critically reviewed the text and selected the

Intensity-modulated radiotherapy (IMRT) for carcinoma of the maxillary sinus: A comparison of IMRT planning systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahmed, Raef S.; Ove, Roger; Duan, Jun

2006-10-01

The treatment of maxillary sinus carcinoma with forward planning can be technically difficult when the neck also requires radiotherapy. This difficulty arises because of the need to spare the contralateral face while treating the bilateral neck. There is considerable potential for error in clinical setup and treatment delivery. We evaluated intensity-modulated radiotherapy (IMRT) as an improvement on forward planning, and compared several inverse planning IMRT platforms. A composite dose-volume histogram (DVH) was generated from a complex forward planned case. We compared the results with those generated by sliding window fixed field dynamic multileaf collimator (MLC) IMRT, using sets of coplanarmore » beams. All setups included an anterior posterior (AP) beam, and 3-, 5-, 7-, and 9-field configurations were evaluated. The dose prescription and objective function priorities were invariant. We also evaluated 2 commercial tomotherapy IMRT delivery platforms. DVH results from all of the IMRT approaches compared favorably with the forward plan. Results for the various inverse planning approaches varied considerably across platforms, despite an attempt to prescribe the therapy similarly. The improvement seen with the addition of beams in the fixed beam sliding window case was modest. IMRT is an effective means of delivering radiotherapy reliably in the complex setting of maxillary sinus carcinoma with neck irradiation. Differences in objective function definition and optimization algorithms can lead to unexpected differences in the final dose distribution, and our evaluation suggests that these factors are more significant than the beam arrangement or number of beams.« less

Time-varying spatial data integration and visualization: 4 Dimensions Environmental Observations Platform (4-DEOS)

NASA Astrophysics Data System (ADS)

Paciello, Rossana; Coviello, Irina; Filizzola, Carolina; Genzano, Nicola; Lisi, Mariano; Mazzeo, Giuseppe; Pergola, Nicola; Sileo, Giancanio; Tramutoli, Valerio

2014-05-01

In environmental studies the integration of heterogeneous and time-varying data, is a very common requirement for investigating and possibly visualize correlations among physical parameters underlying the dynamics of complex phenomena. Datasets used in such kind of applications has often different spatial and temporal resolutions. In some case superimposition of asynchronous layers is required. Traditionally the platforms used to perform spatio-temporal visual data analyses allow to overlay spatial data, managing the time using 'snapshot' data model, each stack of layers being labeled with different time. But this kind of architecture does not incorporate the temporal indexing neither the third spatial dimension which is usually given as an independent additional layer. Conversely, the full representation of a generic environmental parameter P(x,y,z,t) in the 4D space-time domain could allow to handle asynchronous datasets as well as less traditional data-products (e.g. vertical sections, punctual time-series, etc.) . In this paper we present the 4 Dimensions Environmental Observation Platform (4-DEOS), a system based on a web services architecture Client-Broker-Server. This platform is a new open source solution for both a timely access and an easy integration and visualization of heterogeneous (maps, vertical profiles or sections, punctual time series, etc.) asynchronous, geospatial products. The innovative aspect of the 4-DEOS system is that users can analyze data/products individually moving through time, having also the possibility to stop the display of some data/products and focus on other parameters for better studying their temporal evolution. This platform gives the opportunity to choose between two distinct display modes for time interval or for single instant. Users can choose to visualize data/products in two ways: i) showing each parameter in a dedicated window or ii) visualize all parameters overlapped in a single window. A sliding time bar, allows to follow the temporal evolution of the selected data/product. With this software, users have the possibility to identify events partially correlated each other not only in the spatial dimension but also in the time domain even at different time lags.

Possible near-IR channels for remote sensing precipitable water vapor from geostationary satellite platforms

NASA Technical Reports Server (NTRS)

Gao, B.-C.; Goetz, A. F. H.; Westwater, Ed R.; Conel, J. E.; Green, R. O.

1993-01-01

Remote sensing of troposheric water vapor profiles from current geostationary weather satellites is made using a few broadband infrared (IR) channels in the 6-13 micron region. Uncertainties greater than 20% exist in derived water vapor values just above the surface from the IR emission measurements. In this paper, we propose three near-IR channels, one within the 0.94-micron water vapor band absorption region, and the other two in nearby atmospheric windows, for remote sensing of precipitable water vapor over land areas, excluding lakes and rivers, during daytime from future geostationary satellite platforms. The physical principles are as follows. The reflectance of most surface targets varies approximately linearly with wavelength near 1 micron. The solar radiation on the sun-surface-sensor ray path is attenuated by atmospheric water vapor. The ratio of the radiance from the absorption channel with the radiances from the two window channels removes the surface reflectance effects and yields approximately the mean atmospheric water vapor transmittance of the absorption channel. The integrated water vapor amount from ground to space can be obtained with a precision of better than 5% from the mean transmittance. Because surface reflectances vary slowly with time, temporal variation of precipitable water vapor can be determined reliably. High spatial resolution, precipitable water vapor images are derived from spectral data collected by the Airborne Visable-Infrared Imaging Spectrometer, which measures solar radiation reflected by the surface in the 0.4-2.5 micron region in 10-nm channels and has a ground instantaneous field of view of 20 m from its platform on an ER-2 aircraft at 20 km. The proposed near-IR reflectance technique would complement the IR emission techniques for remote sensing of water vapor profiles from geostationary satellite platforms, especially in the boundary layer where most of the water vapor is located.

How smartphones are changing the face of mobile and participatory healthcare: an overview, with example from eCAALYX.

PubMed

Boulos, Maged N Kamel; Wheeler, Steve; Tavares, Carlos; Jones, Ray

2011-04-05

The latest generation of smartphones are increasingly viewed as handheld computers rather than as phones, due to their powerful on-board computing capability, capacious memories, large screens and open operating systems that encourage application development. This paper provides a brief state-of-the-art overview of health and healthcare smartphone apps (applications) on the market today, including emerging trends and market uptake. Platforms available today include Android, Apple iOS, RIM BlackBerry, Symbian, and Windows (Windows Mobile 6.x and the emerging Windows Phone 7 platform). The paper covers apps targeting both laypersons/patients and healthcare professionals in various scenarios, e.g., health, fitness and lifestyle education and management apps; ambient assisted living apps; continuing professional education tools; and apps for public health surveillance. Among the surveyed apps are those assisting in chronic disease management, whether as standalone apps or part of a BAN (Body Area Network) and remote server configuration. We describe in detail the development of a smartphone app within eCAALYX (Enhanced Complete Ambient Assisted Living Experiment, 2009-2012), an EU-funded project for older people with multiple chronic conditions. The eCAALYX Android smartphone app receives input from a BAN (a patient-wearable smart garment with wireless health sensors) and the GPS (Global Positioning System) location sensor in the smartphone, and communicates over the Internet with a remote server accessible by healthcare professionals who are in charge of the remote monitoring and management of the older patient with multiple chronic conditions. Finally, we briefly discuss barriers to adoption of health and healthcare smartphone apps (e.g., cost, network bandwidth and battery power efficiency, usability, privacy issues, etc.), as well as some workarounds to mitigate those barriers.

How smartphones are changing the face of mobile and participatory healthcare: an overview, with example from eCAALYX

PubMed Central

2011-01-01

The latest generation of smartphones are increasingly viewed as handheld computers rather than as phones, due to their powerful on-board computing capability, capacious memories, large screens and open operating systems that encourage application development. This paper provides a brief state-of-the-art overview of health and healthcare smartphone apps (applications) on the market today, including emerging trends and market uptake. Platforms available today include Android, Apple iOS, RIM BlackBerry, Symbian, and Windows (Windows Mobile 6.x and the emerging Windows Phone 7 platform). The paper covers apps targeting both laypersons/patients and healthcare professionals in various scenarios, e.g., health, fitness and lifestyle education and management apps; ambient assisted living apps; continuing professional education tools; and apps for public health surveillance. Among the surveyed apps are those assisting in chronic disease management, whether as standalone apps or part of a BAN (Body Area Network) and remote server configuration. We describe in detail the development of a smartphone app within eCAALYX (Enhanced Complete Ambient Assisted Living Experiment, 2009-2012), an EU-funded project for older people with multiple chronic conditions. The eCAALYX Android smartphone app receives input from a BAN (a patient-wearable smart garment with wireless health sensors) and the GPS (Global Positioning System) location sensor in the smartphone, and communicates over the Internet with a remote server accessible by healthcare professionals who are in charge of the remote monitoring and management of the older patient with multiple chronic conditions. Finally, we briefly discuss barriers to adoption of health and healthcare smartphone apps (e.g., cost, network bandwidth and battery power efficiency, usability, privacy issues, etc.), as well as some workarounds to mitigate those barriers. PMID:21466669

Detailed quantification of delta subsidence, compaction and interaction with man-made structures: the case of the NCA airport, France

NASA Astrophysics Data System (ADS)

Cavalié, O.; Sladen, A.; Kelner, M.

2015-06-01

River deltas are dynamic costal systems and their evolutions are closely monitored as it often concentrates vital natural resources for the surrounding areas. Many deltas, worldwide, experience subsidence due to geological processes (sediment loading and compaction) or human activities (groundwater or hydrocarbon extraction, land reclamation). This causes shoreline erosion or wetland loss which represent serious issues for the population. In this study, we investigate the dynamic of the Var delta (France) where reclaimed lands over sea have been built to host the Nice côte d'Azur airport (NCA). Actually, the stability of this infrastructure is a permanent concern since, in 1979, a newly built extension of the runway platform collapsed in the sea, causing important damages. The project of land extension stopped, but the present airport platform is still located on reclaimed land. Factors that can trigger such catastrophic landslide are thought to be linked to the delta activity and the artificial airport platform load. We used, therefore, Envisat InSAR data to measure accurately the ground deformation of the area that includes the Var delta and NCA airport. Combining data from ascending and descending orbits, we estimated the east-west and vertical components of the deformation and obtained very accurate displacement rate (with a 1σ error of 0.25 mm yr-1). We found that nearly all the deformation is vertical and impacts the whole Var delta. The Var valley subsides at a very low rate (0.5-1 mm yr-1) but downstream the subsidence rate increases and a clear jump is observed at the transition with the reclaimed lands (1-2 mm yr-1). On average, the reclaimed lands subside at 3 mm yr-1. Since the subsidence rate increases in correlation with the sediment thickness, we interpret it as the compaction of the delta quaternary sedimentary wedge. In addition, three areas subsides faster (between 5 and 10 mm yr-1), with one calling for more attention as it is the largest and overlooks the steep Var canyon. The progressive increase of subsidence rates toward the sea also suggests that the underwater parts of the margins could subside at rates well above 10 mm yr-1.

Detailed quantification of delta subsidence, compaction and interaction with man-made structures: the case of the NCA airport, France

NASA Astrophysics Data System (ADS)

Cavalié, O.; Sladen, A.; Kelner, M.

2015-09-01

River deltas are dynamic coastal systems and their evolutions are closely monitored as it often concentrates vital natural resources for the surrounding areas. Many deltas worldwide experience subsidence due to geological processes (sediment loading and compaction) or human activities (groundwater or hydrocarbon extraction, land reclamation). This causes shoreline erosion or wetland loss which represent serious issues for the population. In this study we investigate the dynamic of the Var delta (France) where reclaimed lands over sea have been built to host the Nice côte d'Azur airport (NCA). Actually, the stability of this infrastructure is a permanent concern since, in 1979, a newly built extension of the runway platform collapsed in the sea, causing important damages. The project of land extension stopped, but the present airport platform is still located on reclaimed land. Factors that can trigger such catastrophic landslide are thought to be linked to the delta activity and the artificial airport platform load. We used, therefore, Envisat InSAR data to measure accurately the ground deformation of the area that includes the Var delta and NCA airport. Combining data from ascending and descending orbits, we estimated the east-west and vertical components of the deformation and obtained very accurate displacement rate (with a 1σ error of 0.25 mm yr-1). We found that nearly all the deformation is vertical and impacts the whole Var delta. The Var valley subsides at a very low rate (0.5-1 mm yr-1) but downstream the subsidence rate increases and a clear jump is observed at the transition with the reclaimed lands (1-2 mm yr-1). On average, the reclaimed lands subside at 3 mm yr-1. Since the subsidence rate increases in correlation with the sediment thickness, we interpret it as the compaction of the delta quaternary sedimentary wedge. In addition, three areas subside faster (between 5 and 10 mm yr-1), with one calling for more attention as it is the largest and overlooks the steep Var canyon. The progressive increase of subsidence rates toward the sea also suggests that the underwater parts of the margins could subside at rates well above 10 mm yr-1.

Empowering open systems through cross-platform interoperability

NASA Astrophysics Data System (ADS)

Lyke, James C.

2014-06-01

Most of the motivations for open systems lie in the expectation of interoperability, sometimes referred to as "plug-and-play". Nothing in the notion of "open-ness", however, guarantees this outcome, which makes the increased interest in open architecture more perplexing. In this paper, we explore certain themes of open architecture. We introduce the concept of "windows of interoperability", which can be used to align disparate portions of architecture. Such "windows of interoperability", which concentrate on a reduced set of protocol and interface features, might achieve many of the broader purposes assigned as benefits in open architecture. Since it is possible to engineer proprietary systems that interoperate effectively, this nuanced definition of interoperability may in fact be a more important concept to understand and nurture for effective systems engineering and maintenance.

Forensic Analysis of Windows Hosts Using UNIX-based Tools

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cory Altheide

2004-07-19

Many forensic examiners are introduced to UNIX-based forensic utilities when faced with investigating a UNIX-like operating system for the first time. They will use these utilities for this very specific task, because in many cases these tools are the only ones for the given job. For example, at the time of this writing, given a FreeBSD 5.x file system, the author's only choice is to use The Coroner's Toolkit running on FreeBSD 5.x. However, many of the same tools examiners use for the occasional UNIX-like system investigation are extremely capable when a Windows system is the target. Indeed, the Linuxmore » operating system itself can prove to be an extremely useful forensics platform with very little use of specialized forensics utilities at all.« less

Learning Management Platform for CyberCIEGE

DTIC Science & Technology

2011-12-01

developments were done using the NetBeans Integrated Development Environment (IDE) 7.0, which is a free and open source IDE. Some of these...developments could be implemented using the GUI design features of NetBeans . However, it was not done so because the existing Campaign Analyzer code base...directory through a dialog window. Also, the existing directory structures are not consistent with NetBeans project management assumptions and thus

Convective Heat Transfer in Internal Gas Flows with Temperature-Dependent Properties.

DTIC Science & Technology

1982-06-30

and carbon dioxide in order to examine the effects of physica’, properties differing from those of air. Helium was chosen to reore- sent the behavior of...monatomic gases and carbon dioxide because the temper- azure dependencies of its transoort oroperties differs mar’ ed-v frorn those of air. He...conditions cor- responding to pure forced convection and to significant buoyancy forces in the thermal entry region. For carbon dioxide only temperatures

U.S. Permafrost Delegation Visit to the People’s Republic of China, 15-31 July 1984.

DTIC Science & Technology

1985-06-01

Pewv lectured at Geological Institute. Ministry hosted banquet at Beijing Duck Restaurant. 17 July Visits to Temple of Azure Clouds , Temple of Sleeping...3) Locomotives, (4) Transportation, (5) Railway Standards, (6) Computer Applications, (7) Information, and (8) Signals and Communication. The... text ) - The field trip route tra- versed the center of this scene from the southeast to northwest corners. The lowlands in the eastern half are largely

The Development of Strategic Air Command 1946-1981 (A Chronological History)

DTIC Science & Technology

1982-07-01

lightning flashes red. Azure , two clouds proper, one issuing from sinister chief and one issuing from dexter base, a cubit arm in armor in bend...prepared the text . He was ably assisted by Mr. Sheldon A. Goldberg, who performed much of the research effort and selected the photographs accompanying...the text . CMSgt Herman F. Martin and Amn Debra J. Page were responsible for the photo layout work and Ms. D. Ruth Willett accomplished the

Fixed-bed column performances of azure-II and auramine-O adsorption by Pinus eldarica stalks activated carbon and its composite with zno nanoparticles: Optimization by response surface methodology based on central composite design.

PubMed

Jafari, Maryam; Rahimi, Mahmood Reza; Ghaedi, Mehrorang; Javadian, Hamedreza; Asfaram, Arash

2017-12-01

A continuous adsorption was used for removal of azure II (AZ II) and auramine O (AO) from aqueous solutions using Pinus eldarica stalks activated carbon (PES-AC) from aqueous solutions. The effects of initial dye concentration, flow rate, bed height and contact time on removal percentage of AO and AZ II were evaluated and optimized by central composite design (CCD) at optimum pH = 7.0. ZnO nanoparticles loaded on activated carbon were also used to remove AO and AZ II at pH = 7.0 and other optimum conditions. The breakthrough curves were obtained at different flow rates, initial dye concentrations and bed heights and the experimental data were fitted by Thomas, Adams-Bohart and Yoon-Nelson models. The main parameters of fixed-bed column including its adsorption capacity at breakthrough point (q b ), adsorption capacity at saturation point (q s ), mass transfer zone (MTZ), total removal percentage (R%), and empty bed contact time (EBCT) were calculated. The removal percentages calculated for AZ II and AO II were in the range of 51.6-61.1% and 40.6-61.6%, respectively. Bed adsorption capacity (N 0 ) and critical bed depth (Z 0 ) were obtained by BDST model. Copyright © 2017 Elsevier Inc. All rights reserved.

Interferometer for Space Station Windows

NASA Technical Reports Server (NTRS)

Hall, Gregory

2003-01-01

Inspection of space station windows for micrometeorite damage would be a difficult task insitu using current inspection techniques. Commercially available optical profilometers and inspection systems are relatively large, about the size of a desktop computer tower, and require a stable platform to inspect the test object. Also, many devices currently available are designed for a laboratory or controlled environments requiring external computer control. This paper presents an approach using a highly developed optical interferometer to inspect the windows from inside the space station itself using a self- contained hand held device. The interferometer would be capable as a minimum of detecting damage as small as one ten thousands of an inch in diameter and depth while interrogating a relatively large area. The current developmental state of this device is still in the proof of concept stage. The background section of this paper will discuss the current state of the art of profilometers as well as the desired configuration of the self-contained, hand held device. Then, a discussion of the developments and findings that will allow the configuration change with suggested approaches appearing in the proof of concept section.

Adaptive infrared-reflecting systems inspired by cephalopods

NASA Astrophysics Data System (ADS)

Xu, Chengyi; Stiubianu, George T.; Gorodetsky, Alon A.

2018-03-01

Materials and systems that statically reflect radiation in the infrared region of the electromagnetic spectrum underpin the performance of many entrenched technologies, including building insulation, energy-conserving windows, spacecraft components, electronics shielding, container packaging, protective clothing, and camouflage platforms. The development of their adaptive variants, in which the infrared-reflecting properties dynamically change in response to external stimuli, has emerged as an important unmet scientific challenge. By drawing inspiration from cephalopod skin, we developed adaptive infrared-reflecting platforms that feature a simple actuation mechanism, low working temperature, tunable spectral range, weak angular dependence, fast response, stability to repeated cycling, amenability to patterning and multiplexing, autonomous operation, robust mechanical properties, and straightforward manufacturability. Our findings may open opportunities for infrared camouflage and other technologies that regulate infrared radiation.

Enhancing data utilization through adoption of cloud-based data architectures (Invited Paper 211869)

NASA Astrophysics Data System (ADS)

Kearns, E. J.

2017-12-01

A traditional approach to data distribution and utilization of open government data involves continuously moving those data from a central government location to each potential user, who would then utilize them on their local computer systems. An alternate approach would be to bring those users to the open government data, where users would also have access to computing and analytics capabilities that would support data utilization. NOAA's Big Data Project is exploring such an alternate approach through an experimental collaboration with Amazon Web Services, Google Cloud Platform, IBM, Microsoft Azure, and the Open Commons Consortium. As part of this ongoing experiment, NOAA is providing open data of interest which are freely hosted by the Big Data Project Collaborators, who provide a variety of cloud-based services and capabilities to enable utilization by data users. By the terms of the agreement, the Collaborators may charge for those value-added services and processing capacities to recover their costs to freely host the data and to generate profits if so desired. Initial results have shown sustained increases in data utilization from 2 to over 100 times previously-observed access patterns from traditional approaches. Significantly increased utilization speed as compared to the traditional approach has also been observed by NOAA data users who have volunteered their experiences on these cloud-based systems. The potential for implementing and sustaining the alternate cloud-based approach as part of a change in operational data utilization strategies will be discussed.

Advancing computational methods for calibration of the Soil and Water Assessment Tool (SWAT): Application for modeling climate change impacts on water resources in the Upper Neuse Watershed of North Carolina

NASA Astrophysics Data System (ADS)

Ercan, Mehmet Bulent

Watershed-scale hydrologic models are used for a variety of applications from flood prediction, to drought analysis, to water quality assessments. A particular challenge in applying these models is calibration of the model parameters, many of which are difficult to measure at the watershed-scale. A primary goal of this dissertation is to contribute new computational methods and tools for calibration of watershed-scale hydrologic models and the Soil and Water Assessment Tool (SWAT) model, in particular. SWAT is a physically-based, watershed-scale hydrologic model developed to predict the impact of land management practices on water quality and quantity. The dissertation follows a manuscript format meaning it is comprised of three separate but interrelated research studies. The first two research studies focus on SWAT model calibration, and the third research study presents an application of the new calibration methods and tools to study climate change impacts on water resources in the Upper Neuse Watershed of North Carolina using SWAT. The objective of the first two studies is to overcome computational challenges associated with calibration of SWAT models. The first study evaluates a parallel SWAT calibration tool built using the Windows Azure cloud environment and a parallel version of the Dynamically Dimensioned Search (DDS) calibration method modified to run in Azure. The calibration tool was tested for six model scenarios constructed using three watersheds of increasing size (the Eno, Upper Neuse, and Neuse) for both a 2 year and 10 year simulation duration. Leveraging the cloud as an on demand computing resource allowed for a significantly reduced calibration time such that calibration of the Neuse watershed went from taking 207 hours on a personal computer to only 3.4 hours using 256 cores in the Azure cloud. The second study aims at increasing SWAT model calibration efficiency by creating an open source, multi-objective calibration tool using the Non-Dominated Sorting Genetic Algorithm II (NSGA-II). This tool was demonstrated through an application for the Upper Neuse Watershed in North Carolina, USA. The objective functions used for the calibration were Nash-Sutcliffe (E) and Percent Bias (PB), and the objective sites were the Flat, Little, and Eno watershed outlets. The results show that the use of multi-objective calibration algorithms for SWAT calibration improved model performance especially in terms of minimizing PB compared to the single objective model calibration. The third study builds upon the first two studies by leveraging the new calibration methods and tools to study future climate impacts on the Upper Neuse watershed. Statistically downscaled outputs from eight Global Circulation Models (GCMs) were used for both low and high emission scenarios to drive a well calibrated SWAT model of the Upper Neuse watershed. The objective of the study was to understand the potential hydrologic response of the watershed, which serves as a public water supply for the growing Research Triangle Park region of North Carolina, under projected climate change scenarios. The future climate change scenarios, in general, indicate an increase in precipitation and temperature for the watershed in coming decades. The SWAT simulations using the future climate scenarios, in general, suggest an increase in soil water and water yield, and a decrease in evapotranspiration within the Upper Neuse watershed. In summary, this dissertation advances the field of watershed-scale hydrologic modeling by (i) providing some of the first work to apply cloud computing for the computationally-demanding task of model calibration; (ii) providing a new, open source library that can be used by SWAT modelers to perform multi-objective calibration of their models; and (iii) advancing understanding of climate change impacts on water resources for an important watershed in the Research Triangle Park region of North Carolina. The third study leveraged the methodological advances presented in the first two studies. Therefore, the dissertation contains three independent by interrelated studies that collectively advance the field of watershed-scale hydrologic modeling and analysis.

A multi-faceted approach to promote knowledge translation platforms in eastern Mediterranean countries: climate for evidence-informed policy.

PubMed

El-Jardali, Fadi; Ataya, Nour; Jamal, Diana; Jaafar, Maha

2012-05-06

Limited work has been done to promote knowledge translation (KT) in the Eastern Mediterranean Region (EMR). The objectives of this study are to: 1.assess the climate for evidence use in policy; 2.explore views and practices about current processes and weaknesses of health policymaking; 3.identify priorities including short-term requirements for policy briefs; and 4.identify country-specific requirements for establishing KT platforms. Senior policymakers, stakeholders and researchers from Algeria, Bahrain, Egypt, Iran, Jordan, Lebanon, Oman, Sudan, Syria, Tunisia, and Yemen participated in this study. Questionnaires were used to assess the climate for use of evidence and identify windows of opportunity and requirements for policy briefs and for establishing KT platforms. Current processes and weaknesses of policymaking were appraised using case study scenarios. Closed-ended questions were analyzed descriptively. Qualitative data was analyzed using thematic analysis. KT activities were not frequently undertaken by policymakers and researchers in EMR countries, research evidence about high priority policy issues was rarely made available, and interaction between policymakers and researchers was limited, and policymakers rarely identified or created places for utilizing research evidence in decision-making processes. Findings emphasized the complexity of policymaking. Donors, political regimes, economic goals and outdated laws were identified as key drivers. Lack of policymakers' abilities to think strategically, constant need to make quick decisions, limited financial resources, and lack of competent and trained human resources were suggested as main weaknesses. Despite the complexity of policymaking processes in countries from this region, the absence of a structured process for decision making, and the limited engagement of policymakers and researchers in KT activities, there are windows of opportunity for moving towards more evidence informed policymaking.

A multi-faceted approach to promote knowledge translation platforms in eastern Mediterranean countries: climate for evidence-informed policy

PubMed Central

2012-01-01

Objectives Limited work has been done to promote knowledge translation (KT) in the Eastern Mediterranean Region (EMR). The objectives of this study are to: 1.assess the climate for evidence use in policy; 2.explore views and practices about current processes and weaknesses of health policymaking; 3.identify priorities including short-term requirements for policy briefs; and 4.identify country-specific requirements for establishing KT platforms. Methods Senior policymakers, stakeholders and researchers from Algeria, Bahrain, Egypt, Iran, Jordan, Lebanon, Oman, Sudan, Syria, Tunisia, and Yemen participated in this study. Questionnaires were used to assess the climate for use of evidence and identify windows of opportunity and requirements for policy briefs and for establishing KT platforms. Current processes and weaknesses of policymaking were appraised using case study scenarios. Closed-ended questions were analyzed descriptively. Qualitative data was analyzed using thematic analysis. Results KT activities were not frequently undertaken by policymakers and researchers in EMR countries, research evidence about high priority policy issues was rarely made available, and interaction between policymakers and researchers was limited, and policymakers rarely identified or created places for utilizing research evidence in decision-making processes. Findings emphasized the complexity of policymaking. Donors, political regimes, economic goals and outdated laws were identified as key drivers. Lack of policymakers’ abilities to think strategically, constant need to make quick decisions, limited financial resources, and lack of competent and trained human resources were suggested as main weaknesses. Conclusion Despite the complexity of policymaking processes in countries from this region, the absence of a structured process for decision making, and the limited engagement of policymakers and researchers in KT activities, there are windows of opportunity for moving towards more evidence informed policymaking. PMID:22559007

Multiphase Structural Evolution of a Continental Margin During Obduction Orogeny: Insights From the Jebel Akhdar Dome, Oman Mountains

NASA Astrophysics Data System (ADS)

Grobe, A.; Virgo, S.; von Hagke, C.; Urai, J. L.; Littke, R.

2018-03-01

The structural evolution of the carbonate platform in the footwall of the Semail ophiolite emplaced onto the passive continental margin of Arabia helps to better understand the early stages of obduction-related orogens. These early stages are rarely observable in other orogens as they are mostly overprinted by later mountain building phases. We present an extensive structural analysis of the Jebel Akhdar anticline, the largest tectonic window of the Oman Mountains, and integrate it on different scales. Outcrop observations can be linked to plate motion data, providing an absolute timeframe for structural generations consistent with radiometric dating of veins. Top-to-S overthrusting of the Semail ophiolite and Hawasina nappes onto the carbonate platform during high plate convergence rates between Arabia and Eurasia caused rapid burial and overpressure, generation and migration of hydrocarbons, and bedding-confined veins, but no major deformation in the carbonate platform. At reduced convergence rates, subsequent tectonic thinning of the ophiolite took place above a top-to-NNE, crustal-scale ductile shear zone, deforming existing veins and forming a cleavage in clay-rich layers in early Campanian times. Ongoing extension occurred along normal- to oblique-slip faults, forming horst-graben structures and a precursor of the Jebel Akhdar dome (Campanian to Maastrichtian). This was followed by NE-SW oriented ductile shortening and the formation of the Jebel Akhdar dome, deforming the earlier structures. Thereafter, exhumation was associated with low-angle normal faults on the northern flank of the anticline. We correlate the top-to-NNE crustal-scale shear zone with a similar structure in the Saih Hatat window to develop a unified model of the tectonic evolution of the Oman Mountains.

MAPPER: A personal computer map projection tool

NASA Technical Reports Server (NTRS)

Bailey, Steven A.

1993-01-01

MAPPER is a set of software tools designed to let users create and manipulate map projections on a personal computer (PC). The capability exists to generate five popular map projections. These include azimuthal, cylindrical, mercator, lambert, and sinusoidal projections. Data for projections are contained in five coordinate databases at various resolutions. MAPPER is managed by a system of pull-down windows. This interface allows the user to intuitively create, view and export maps to other platforms.

Proceedings of the Antenna Applications Symposium (32nd) Held in Monticello, Illinois on 16-18 September 2008. Volume 2

DTIC Science & Technology

2008-12-20

operational concepts. The adaptation or translations of these systems can provide an effective means of addressing many current and emerging challenges . The...providing stealth, cloaking, mimicry and other capabilities such as EM windowing to these platforms presents many challenges as their operational role...physical insight into a complex system or emerging technological challenges . A bio-system that shares synergistic goals with this complex system

Detail view of the forward section, port side, of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the forward section, port side, of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the removal of the Forward Reaction Control System Module from the nose section, the ground-support window covers and the strongback attached to the payload bay door. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Integration of CW / Radionucleotide Detection Systems to the Fido XT Explosives Detector

DTIC Science & Technology

2008-07-31

explosives detected by the Fido XT. Additionally, a platform for centralized storage and processing of Fido XT data files collected in house, targeted...fused silica glass wool (obtained from Restek). The fluorescent signal was easily washed out of the flow cell by a nominal amount of buffer...detector with supporting NRE was processed . The Interceptor components were configured to operate under a Windows CE processor environment, and to

EPICS SCA CLIENTS ON THE .NET X64 PLATFORM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Timossi, Chris; Nishimura, Hiroshi

2006-10-19

We have developed a .NET assembly, which we call SCA.NET,which we have been using for building EPICS based control roomapplications at the Advanced Light Source (ALS). In this paper we reporton our experiences building a 64-bit version of SCA.NET and theunderlying channel access libraries for Windows XP x64 (using a dual coreAMD Athlon CPU). We also report on our progress in building newaccelerator control applications for this environment.

RMG An Open Source Electronic Structure Code for Multi-Petaflops Calculations

NASA Astrophysics Data System (ADS)

Briggs, Emil; Lu, Wenchang; Hodak, Miroslav; Bernholc, Jerzy

RMG (Real-space Multigrid) is an open source, density functional theory code for quantum simulations of materials. It solves the Kohn-Sham equations on real-space grids, which allows for natural parallelization via domain decomposition. Either subspace or Davidson diagonalization, coupled with multigrid methods, are used to accelerate convergence. RMG is a cross platform open source package which has been used in the study of a wide range of systems, including semiconductors, biomolecules, and nanoscale electronic devices. It can optionally use GPU accelerators to improve performance on systems where they are available. The recently released versions (>2.0) support multiple GPU's per compute node, have improved performance and scalability, enhanced accuracy and support for additional hardware platforms. New versions of the code are regularly released at http://www.rmgdft.org. The releases include binaries for Linux, Windows and MacIntosh systems, automated builds for clusters using cmake, as well as versions adapted to the major supercomputing installations and platforms. Several recent, large-scale applications of RMG will be discussed.

Project CHECO Southeast Asia Report. USAF Search and Rescue in Southeast Asia, 1 July 1969 - 31 December 1970

DTIC Science & Technology

1971-04-23

airpower to meet a multitude of requirements. The varied applications of airpower have involved the full spectrum of USAF aerospace vehicles, support...shield of the sky proper, a sphere azure , rimmed and gridded or, superimposed in the southwest areas of the sphere a cross and three lightning bolt...Plan 69-1 to provide two full squadrons of HH-53 Super Jolly Greens or BUFFs as they were known in SEA--for Big Ugly Friendly Fellows, as one

Tailoring double Fano profiles with plasmon-assisted quantum interference in hybrid exciton-plasmon system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, Dongxing; Wu, Jiarui; Gu, Ying, E-mail: ygu@pku.edu.cn

2014-09-15

We propose tailoring of the double Fano profiles via plasmon-assisted quantum interference in a hybrid exciton-plasmon system. Tailoring is performed by the interference between two exciton channels interacting with a common localized surface plasmon. Using an applied field of low intensity, the absorption spectrum of the hybrid system reveals a double Fano lineshape with four peaks. For relatively large field intensity, a broad flat window in the absorption spectrum appears which results from the destructive interference between excitons. Because of strong constructive interference, this window vanishes as intensity is further increased. We have designed a nanometer bandpass optical filter formore » visible light based on tailoring of the optical spectrum. This study provides a platform for quantum interference that may have potential applications in ultracompact tunable quantum devices.« less

BrainLiner: A Neuroinformatics Platform for Sharing Time-Aligned Brain-Behavior Data

PubMed Central

Takemiya, Makoto; Majima, Kei; Tsukamoto, Mitsuaki; Kamitani, Yukiyasu

2016-01-01

Data-driven neuroscience aims to find statistical relationships between brain activity and task behavior from large-scale datasets. To facilitate high-throughput data processing and modeling, we created BrainLiner as a web platform for sharing time-aligned, brain-behavior data. Using an HDF5-based data format, BrainLiner treats brain activity and data related to behavior with the same salience, aligning both behavioral and brain activity data on a common time axis. This facilitates learning the relationship between behavior and brain activity. Using a common data file format also simplifies data processing and analyses. Properties describing data are unambiguously defined using a schema, allowing machine-readable definition of data. The BrainLiner platform allows users to upload and download data, as well as to explore and search for data from the web platform. A WebGL-based data explorer can visualize highly detailed neurophysiological data from within the web browser, and a data-driven search feature allows users to search for similar time windows of data. This increases transparency, and allows for visual inspection of neural coding. BrainLiner thus provides an essential set of tools for data sharing and data-driven modeling. PMID:26858636

Window into the Caledonian orogen: Structure of the crust beneath the East Shetland platform, United Kingdom

USGS Publications Warehouse

McBride, J.H.; England, R.W.

1999-01-01

Reprocessing and interpretation of commercial and deep seismic reflection data across the East Shetland platform and its North Sea margin provide a new view of crustal subbasement structure beneath a poorly known region of the British Caledonian orogen. The East Shetland platform, east of the Great Glen strike-slip fault system, is one of the few areas of the offshore British Caledonides that remained relatively insulated from the Mesozoic and later rifting that involved much of the area around the British Isles, thus providing an "acoustic window" into the deep structure of the orogen. Interpretation of the reflection data suggests that the crust beneath the platform retains a significant amount of its original Caledonian and older architecture. The upper to middle crust is typically poorly reflective except for individual prominent dipping reflectors with complex orientations that decrease in dip with depth and merge with a lower crustal layer of high reflectivity. The three-dimensional structural orientation of the reflectors beneath the East Shetland platform is at variance with Caledonian reflector trends observed elsewhere in the Caledonian orogen (e.g., north of the Scottish mainland), emphasizing the unique tectonic character of this part of the orogen. Upper to middle crustal reflectors are interpreted as Caledonian or older thrust surfaces that were possibly reactivated by Devonian extension associated with post-Caledonian orogenic collapse. The appearance of two levels of uneven and diffractive (i.e., corrugated) reflectivity in the lower crust, best developed on east-west-oriented profiles, is characteristic of the East Shetland platform. However, a north-south-oriented profile reveals an interpreted south-vergent folded and imbricated thrust structure in the lower crust that appears to be tied to the two levels of corrugated reflectivity on the east-west profiles. A thrust-belt origin for lower crustal reflectivity would explain its corrugated appearance. Regional seismic velocity models derived from refraction data suggest that this reflectivity correlates with a continuous lower crustal layer that has an intermediate seismic velocity. The lower crustal reflectivity is determined to be older than Mesozoic age by the bending down and truncation of the two reflectivity levels at the western margin of the North Sea Viking graben by a major mantle reflector inferred to be associated with Mesozoic rifting. The results of this study are thus in contrast with orthodox interpretations of the reflective layered lower crust as being caused by mantle-derived igneous intrusion or by deformation fabrics associated with stretching in response to continental rifting.

Open discovery: An integrated live Linux platform of Bioinformatics tools.

PubMed

Vetrivel, Umashankar; Pilla, Kalabharath

2008-01-01

Historically, live linux distributions for Bioinformatics have paved way for portability of Bioinformatics workbench in a platform independent manner. Moreover, most of the existing live Linux distributions limit their usage to sequence analysis and basic molecular visualization programs and are devoid of data persistence. Hence, open discovery - a live linux distribution has been developed with the capability to perform complex tasks like molecular modeling, docking and molecular dynamics in a swift manner. Furthermore, it is also equipped with complete sequence analysis environment and is capable of running windows executable programs in Linux environment. Open discovery portrays the advanced customizable configuration of fedora, with data persistency accessible via USB drive or DVD. The Open Discovery is distributed free under Academic Free License (AFL) and can be downloaded from http://www.OpenDiscovery.org.in.

The Design, Development and Testing of a Multi-process Real-time Software System

DTIC Science & Technology

2007-03-01

programming large systems stems from the complexity of dealing with many different details at one time. A sound engineering approach is to break...controls and 3) is portable to other OS platforms such as Microsoft Windows. Next, to reduce the complexity of the programming tasks, the system...processes depending on how often the process has to check to see if common data was modified. A good method for one process to quickly notify another

Orbit Software Suite

NASA Technical Reports Server (NTRS)

Osgood, Cathy; Williams, Kevin; Gentry, Philip; Brownfield, Dana; Hallstrom, John; Stuit, Tim

2012-01-01

Orbit Software Suite is used to support a variety of NASA/DM (Dependable Multiprocessor) mission planning and analysis activities on the IPS (Intrusion Prevention System) platform. The suite of Orbit software tools (Orbit Design and Orbit Dynamics) resides on IPS/Linux workstations, and is used to perform mission design and analysis tasks corresponding to trajectory/ launch window, rendezvous, and proximity operations flight segments. A list of tools in Orbit Software Suite represents tool versions established during/after the Equipment Rehost-3 Project.

Optimizing Terminal Conditions Using Geometric Guidance for Low-Control Authority Munitions

DTIC Science & Technology

2008-06-01

Lowest altitude allowable for maximum canard deflection per unit of acceleration constant hT δ g Canard deflection per unit of acceleration transition...target within that range window in less than five minutes from time of fire [17]. The launch platform can supply the munition with some preflight...linear 7. The information supplied by the onboard navigation system has no errors 8. The control system is always able to generate the exact amount

A CMake-Based Cross Platform Build System for Tcl/Tk

DTIC Science & Technology

2011-11-01

expressing the logic for generating user-installable packages of the finished package. While specific com- pilation instructions are typically unique to each...Windows com- pilation . This presented a difficulty for the BRL- CAD project in that neither of these systems inte- grated well with BRL-CAD’s own build...build files. 2. Implement enough of the Tcl/Tk–specific com- pilation macro logic in CMake to support build- 1Twylite’s Coffee project uses CMake to

MAPPI-DAT: data management and analysis for protein-protein interaction data from the high-throughput MAPPIT cell microarray platform.

PubMed

Gupta, Surya; De Puysseleyr, Veronic; Van der Heyden, José; Maddelein, Davy; Lemmens, Irma; Lievens, Sam; Degroeve, Sven; Tavernier, Jan; Martens, Lennart

2017-05-01

Protein-protein interaction (PPI) studies have dramatically expanded our knowledge about cellular behaviour and development in different conditions. A multitude of high-throughput PPI techniques have been developed to achieve proteome-scale coverage for PPI studies, including the microarray based Mammalian Protein-Protein Interaction Trap (MAPPIT) system. Because such high-throughput techniques typically report thousands of interactions, managing and analysing the large amounts of acquired data is a challenge. We have therefore built the MAPPIT cell microArray Protein Protein Interaction-Data management & Analysis Tool (MAPPI-DAT) as an automated data management and analysis tool for MAPPIT cell microarray experiments. MAPPI-DAT stores the experimental data and metadata in a systematic and structured way, automates data analysis and interpretation, and enables the meta-analysis of MAPPIT cell microarray data across all stored experiments. MAPPI-DAT is developed in Python, using R for data analysis and MySQL as data management system. MAPPI-DAT is cross-platform and can be ran on Microsoft Windows, Linux and OS X/macOS. The source code and a Microsoft Windows executable are freely available under the permissive Apache2 open source license at https://github.com/compomics/MAPPI-DAT. jan.tavernier@vib-ugent.be or lennart.martens@vib-ugent.be. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press.

End-stage renal disease treated in Provence-Alpes Côte d'Azur: 12-years follow-up and forecast to the year 2030.

PubMed

Durand, Anne-Claire; Jouve, Elisabeth; Delarozière, Jean-Christophe; Boucekine, Mohamed; Izaaryene, Ghizlane; Crémades, Adeline; Mazoué, Franck; Devictor, Bénédicte; Kakar, Asmatullah; Sambuc, Roland; Brunet, Philippe; Gentile, Stéphanie

2018-06-15

This study describes the time trend of renal replacement therapy for end-stage renal disease (ESRD) in the Provence-Alpes Côte d'Azur region (PACA) between 2004 and 2015, and forecasts up to 2030. A longitudinal study was conducted on all ESRD patients treated in PACA and recorded in the French Renal Epidemiology and Information Network (REIN) during this period. Time trends and forecasts to 2030 were analyzed using Poisson regression models. Since 2004, the number of new patients has steadily increased by 3.4% per year (95% CI, 2.8-3.9, p < 0.001) and the number of patients receiving RRT has increased by 3.7% per year (RR 1.037, 95% CI: 1.034-1.039, p < 0.001). If these trends continue, the PACA region will be face with 7371 patients on dialysis and 3891 with a functional renal transplant who will need to be managed in 2030. The two most significant growth rates were the percentage of obese people (RR 1.140, 95% CI: 1.131-1.149, p < 0.001) and those with diabetes (RR 1.070, 95% CI; 1.064-1.075, p < 0.001). This study highlights the increase in the number of ESRD patients over 12 years, with no prospect of stabilization. These findings allow us to anticipate the quality and quantity of care offered and to propose more preventive measures to combat obesity and diabetes.

An Internet of Things System for Underground Mine Air Quality Pollutant Prediction Based on Azure Machine Learning

PubMed Central

Jo, ByungWan

2018-01-01

The implementation of wireless sensor networks (WSNs) for monitoring the complex, dynamic, and harsh environment of underground coal mines (UCMs) is sought around the world to enhance safety. However, previously developed smart systems are limited to monitoring or, in a few cases, can report events. Therefore, this study introduces a reliable, efficient, and cost-effective internet of things (IoT) system for air quality monitoring with newly added features of assessment and pollutant prediction. This system is comprised of sensor modules, communication protocols, and a base station, running Azure Machine Learning (AML) Studio over it. Arduino-based sensor modules with eight different parameters were installed at separate locations of an operational UCM. Based on the sensed data, the proposed system assesses mine air quality in terms of the mine environment index (MEI). Principal component analysis (PCA) identified CH4, CO, SO2, and H2S as the most influencing gases significantly affecting mine air quality. The results of PCA were fed into the ANN model in AML studio, which enabled the prediction of MEI. An optimum number of neurons were determined for both actual input and PCA-based input parameters. The results showed a better performance of the PCA-based ANN for MEI prediction, with R2 and RMSE values of 0.6654 and 0.2104, respectively. Therefore, the proposed Arduino and AML-based system enhances mine environmental safety by quickly assessing and predicting mine air quality. PMID:29561777

An Internet of Things System for Underground Mine Air Quality Pollutant Prediction Based on Azure Machine Learning.

PubMed

Jo, ByungWan; Khan, Rana Muhammad Asad

2018-03-21

The implementation of wireless sensor networks (WSNs) for monitoring the complex, dynamic, and harsh environment of underground coal mines (UCMs) is sought around the world to enhance safety. However, previously developed smart systems are limited to monitoring or, in a few cases, can report events. Therefore, this study introduces a reliable, efficient, and cost-effective internet of things (IoT) system for air quality monitoring with newly added features of assessment and pollutant prediction. This system is comprised of sensor modules, communication protocols, and a base station, running Azure Machine Learning (AML) Studio over it. Arduino-based sensor modules with eight different parameters were installed at separate locations of an operational UCM. Based on the sensed data, the proposed system assesses mine air quality in terms of the mine environment index (MEI). Principal component analysis (PCA) identified CH₄, CO, SO₂, and H₂S as the most influencing gases significantly affecting mine air quality. The results of PCA were fed into the ANN model in AML studio, which enabled the prediction of MEI. An optimum number of neurons were determined for both actual input and PCA-based input parameters. The results showed a better performance of the PCA-based ANN for MEI prediction, with R ² and RMSE values of 0.6654 and 0.2104, respectively. Therefore, the proposed Arduino and AML-based system enhances mine environmental safety by quickly assessing and predicting mine air quality.

Designing communication and remote controlling of virtual instrument network system

NASA Astrophysics Data System (ADS)

Lei, Lin; Wang, Houjun; Zhou, Xue; Zhou, Wenjian

2005-01-01

In this paper, a virtual instrument network through the LAN and finally remote control of virtual instruments is realized based on virtual instrument and LabWindows/CVI software platform. The virtual instrument network system is made up of three subsystems. There are server subsystem, telnet client subsystem and local instrument control subsystem. This paper introduced virtual instrument network structure in detail based on LabWindows. Application procedure design of virtual instrument network communication, the Client/the programming mode of the server, remote PC and server communication far realizing, the control power of the workstation is transmitted, server program and so on essential technical were introduced. And virtual instruments network may connect to entire Internet on. Above-mentioned technology, through measuring the application in the electronic measurement virtual instrument network that is already built up, has verified the actual using value of the technology. Experiment and application validate that this design is resultful.

EasyModeller: A graphical interface to MODELLER

PubMed Central

2010-01-01

Background MODELLER is a program for automated protein Homology Modeling. It is one of the most widely used tool for homology or comparative modeling of protein three-dimensional structures, but most users find it a bit difficult to start with MODELLER as it is command line based and requires knowledge of basic Python scripting to use it efficiently. Findings The study was designed with an aim to develop of "EasyModeller" tool as a frontend graphical interface to MODELLER using Perl/Tk, which can be used as a standalone tool in windows platform with MODELLER and Python preinstalled. It helps inexperienced users to perform modeling, assessment, visualization, and optimization of protein models in a simple and straightforward way. Conclusion EasyModeller provides a graphical straight forward interface and functions as a stand-alone tool which can be used in a standard personal computer with Microsoft Windows as the operating system. PMID:20712861

Advanced Bioinks for 3D Printing: A Materials Science Perspective.

PubMed

Chimene, David; Lennox, Kimberly K; Kaunas, Roland R; Gaharwar, Akhilesh K

2016-06-01

Advanced bioinks for 3D printing are rationally designed materials intended to improve the functionality of printed scaffolds outside the traditional paradigm of the "biofabrication window". While the biofabrication window paradigm necessitates compromise between suitability for fabrication and ability to accommodate encapsulated cells, recent developments in advanced bioinks have resulted in improved designs for a range of biofabrication platforms without this tradeoff. This has resulted in a new generation of bioinks with high print fidelity, shear-thinning characteristics, and crosslinked scaffolds with high mechanical strength, high cytocompatibility, and the ability to modulate cellular functions. In this review, we describe some of the promising strategies being pursued to achieve these goals, including multimaterial, interpenetrating network, nanocomposite, and supramolecular bioinks. We also provide an overview of current and emerging trends in advanced bioink synthesis and biofabrication, and evaluate the potential applications of these novel biomaterials to clinical use.

minimega v. 3.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crussell, Jonathan; Erickson, Jeremy; Fritz, David

minimega is an emulytics platform for creating testbeds of networked devices. The platoform consists of easily deployable tools to facilitate bringing up large networks of virtual machines including Windows, Linux, and Android. minimega allows experiments to be brought up quickly with almost no configuration. minimega also includes tools for simple cluster, management, as well as tools for creating Linux-based virtual machines. This release of minimega includes new emulated sensors for Android devices to improve the fidelity of testbeds that include mobile devices. Emulated sensors include GPS and

A Tutorial on Interfacing the Object Management Group (OMG) Data Distribution Service (DDS) with LabView

NASA Technical Reports Server (NTRS)

Smith, Kevin

2011-01-01

This tutorial will explain the concepts and steps for interfacing a National Instruments LabView virtual instrument (VI) running on a Windows platform with another computer via the Object Management Group (OMG) Data Distribution Service (DDS) as implemented by the Twin Oaks Computing CoreDX. This paper is for educational purposes only and therefore, the referenced source code will be simplistic and void of all error checking. Implementation will be accomplished using the C programming language.

Design of penicillin fermentation process simulation system

NASA Astrophysics Data System (ADS)

Qi, Xiaoyu; Yuan, Zhonghu; Qi, Xiaoxuan; Zhang, Wenqi

2011-10-01

Real-time monitoring for batch process attracts increasing attention. It can ensure safety and provide products with consistent quality. The design of simulation system of batch process fault diagnosis is of great significance. In this paper, penicillin fermentation, a typical non-linear, dynamic, multi-stage batch production process, is taken as the research object. A visual human-machine interactive simulation software system based on Windows operation system is developed. The simulation system can provide an effective platform for the research of batch process fault diagnosis.

Open discovery: An integrated live Linux platform of Bioinformatics tools

PubMed Central

Vetrivel, Umashankar; Pilla, Kalabharath

2008-01-01

Historically, live linux distributions for Bioinformatics have paved way for portability of Bioinformatics workbench in a platform independent manner. Moreover, most of the existing live Linux distributions limit their usage to sequence analysis and basic molecular visualization programs and are devoid of data persistence. Hence, open discovery ‐ a live linux distribution has been developed with the capability to perform complex tasks like molecular modeling, docking and molecular dynamics in a swift manner. Furthermore, it is also equipped with complete sequence analysis environment and is capable of running windows executable programs in Linux environment. Open discovery portrays the advanced customizable configuration of fedora, with data persistency accessible via USB drive or DVD. Availability The Open Discovery is distributed free under Academic Free License (AFL) and can be downloaded from http://www.OpenDiscovery.org.in PMID:19238235

Control of second-harmonic generation in doubly resonant aluminum nitride microrings to address a rubidium two-photon clock transition.

PubMed

Surya, Joshua B; Guo, Xiang; Zou, Chang-Ling; Tang, Hong X

2018-06-01

Nonlinear optical effects have been studied extensively in microresonators as more photonics applications transitions to integrated on-chip platforms. Due to low optical losses and small mode volumes, microresonators are demonstrably the state-of-the-art platform for second-harmonic generation (SHG). However, the working bandwidth of such microresonator-based devices is relatively small, presenting a challenge for applications where a specifically targeted wavelength needs to be addressed. In this Letter, we analyze the phase-matching window and resonance wavelength with respect to varying microring widths, radii, and temperatures. A chip with precise design parameters was fabricated with phase matching realized at the exact wavelength of a two-photon transition of Rb85. This procedure can be generalized to any target pump wavelength in the telecom band with picometer precision.

Solar chulha

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jadhao, P. H.; Patrikar, S. R.

2016-05-06

The main goal of the proposed system is to transfer energy from sun to the cooking load that is located in the kitchen. The energy is first collected by the solar collector lens system and two curve bars of same radius of curvature are mounted parallel and adjacent to each other at different height the solar collector is clamed on this two bars such that solar collector is exactly perpendicular to sunlight. The topology includes an additional feature which is window in the wall through which the beam is collimated is directed in the of kitchen. The solar energy thatmore » is collected is directed by the mirror system into the kitchen, where it is redirected to cooking platform located in the kitchen. The special feature in this system full Indian meal can be made since cooking platform is indoors.« less

Investigation of the Redox Chemistry of Anthraquinone Derivatives Using Density Functional Theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bachman, Jonathan E.; Curtiss, Larry A.; Assary, Rajeev S.

2014-09-25

Application of density functional calculations to compute electrochemical properties such as redox windows, effect of substitution by electron donating and electron withdrawing groups on redox windows, and solvation free energies for ~50 anthraquinone (AQ) derivatives are presented because of their potential as anolytes in all-organic redox flow batteries. Computations suggest that lithium ions can increase (by ~0.4 V) the reduction potential of anthraquinone due to the lithium ion pairing by forming a Lewis base-Lewis acid complex. To design new redox active species, the substitution by electron donating groups are essential to improve the reduction window of AQ with adequate oxidativemore » stability. For instance, a complete methylation of AQ can improve its reduction window by ~0.4 V. The quantum chemical studies of the ~50 AQ derivatives are used to derive a relationship that connects the computed LUMO energy and the reduction potential that can be applied as a descriptor for screening thousands of AQ derivatives. Our computations also suggest that incorporating oxy-methyl dioxolane substituents in the AQ framework can increase its interaction with non-aqueous solvent and improve its solubility. Thermochemical calculations for likely bond breaking decomposition reactions of un-substituted AQ anions suggest that the dianions are relatively stable in the solution. These studies provide ideal platform to perform further combined experimental and theoretical studies to understand the electrochemical reversibility and solubility of new quinone molecules as energy storage materials.« less

An Optical Biosensing Platform using Reprecipitated Polyaniline Microparticles

NASA Astrophysics Data System (ADS)

Nemzer, Louis; Epstein, Arthur

2009-03-01

A great deal of effort remains focused on the goal of developing a continuous in vivo glucose monitoring system for patients with diabetes mellitus. We report a proof-of-concept study on a reagentless optical biosensing platform that circumvents the problems usually associated with direct glucose detection by utilizing the UV-VIS absorption properties of polyaniline, a biocompatible polymer. When the enzyme glucose oxidase is entrapped within reprecipitated polyaniline microparticles, a glucose molecule readily donates two protons and two electrons to the polyaniline, reversibly altering the polymer's oxidation state. The resultant change can be monitored by measuring the absorption at wavelengths that fall within the ``optical window'' for skin. The micro-structured morphology also insures a high surface-area to volume ratio. Data from in vitro prototype devices indicate that in the low enzyme-loading regime, the response can be fit to the Michaelis-Menten model for enzyme kinetics, but at higher enzyme loading, diffusion effects dominate. As a biosensing platform, the system also has the potential to be adapted to detect other biologically relevant analytes, including cholesterol and ethanol.

ProteoWizard: open source software for rapid proteomics tools development.

PubMed

Kessner, Darren; Chambers, Matt; Burke, Robert; Agus, David; Mallick, Parag

2008-11-01

The ProteoWizard software project provides a modular and extensible set of open-source, cross-platform tools and libraries. The tools perform proteomics data analyses; the libraries enable rapid tool creation by providing a robust, pluggable development framework that simplifies and unifies data file access, and performs standard proteomics and LCMS dataset computations. The library contains readers and writers of the mzML data format, which has been written using modern C++ techniques and design principles and supports a variety of platforms with native compilers. The software has been specifically released under the Apache v2 license to ensure it can be used in both academic and commercial projects. In addition to the library, we also introduce a rapidly growing set of companion tools whose implementation helps to illustrate the simplicity of developing applications on top of the ProteoWizard library. Cross-platform software that compiles using native compilers (i.e. GCC on Linux, MSVC on Windows and XCode on OSX) is available for download free of charge, at http://proteowizard.sourceforge.net. This website also provides code examples, and documentation. It is our hope the ProteoWizard project will become a standard platform for proteomics development; consequently, code use, contribution and further development are strongly encouraged.

2D and 3D virtual interactive laboratories of physics on Unity platform

NASA Astrophysics Data System (ADS)

González, J. D.; Escobar, J. H.; Sánchez, H.; De la Hoz, J.; Beltrán, J. R.

2017-12-01

Using the cross-platform game engine Unity, we develop virtual laboratories for PC, consoles, mobile devices and website as an innovative tool to study physics. There is extensive uptake of ICT in the teaching of science and its impact on the learning, and considering the limited availability of laboratories for physics teaching and the difficulties this causes in the learning of school students, we design the virtual laboratories to enhance studentâĂŹs knowledge of concepts in physics. To achieve this goal, we use Unity due to provide support bump mapping, reflection mapping, parallax mapping, dynamics shadows using shadows maps, full-screen post-processing effects and render-to-texture. Unity can use the best variant for the current video hardware and, if none are compatible, to use an alternative shader that may sacrifice features for performance. The control over delivery to mobile devices, web browsers, consoles and desktops is the main reason Unity is the best option among the same kind cross-platform. Supported platforms include Android, Apple TV, Linux, iOS, Nintendo 3DS line, macOS, PlayStation 4, Windows Phone 8, Wii but also an asset server and Nvidia’s PhysX physics engine which is the most relevant tool on Unity for our PhysLab.

Informatics in radiology (infoRAD): free DICOM image viewing and processing software for the Macintosh computer: what's available and what it can do for you.

PubMed

Escott, Edward J; Rubinstein, David

2004-01-01

It is often necessary for radiologists to use digital images in presentations and conferences. Most imaging modalities produce images in the Digital Imaging and Communications in Medicine (DICOM) format. The image files tend to be large and thus cannot be directly imported into most presentation software, such as Microsoft PowerPoint; the large files also consume storage space. There are many free programs that allow viewing and processing of these files on a personal computer, including conversion to more common file formats such as the Joint Photographic Experts Group (JPEG) format. Free DICOM image viewing and processing software for computers running on the Microsoft Windows operating system has already been evaluated. However, many people use the Macintosh (Apple Computer) platform, and a number of programs are available for these users. The World Wide Web was searched for free DICOM image viewing or processing software that was designed for the Macintosh platform or is written in Java and is therefore platform independent. The features of these programs and their usability were evaluated. There are many free programs for the Macintosh platform that enable viewing and processing of DICOM images. (c) RSNA, 2004.

Social anxiety apps: a systematic review and assessment of app descriptors across mobile store platforms.

PubMed

Alyami, Mohsen; Giri, Bachan; Alyami, Hussain; Sundram, Frederick

2017-08-01

The aim of this systematic review is twofold: (1) to characterise the purpose and description of available social anxiety apps and (2) to review the evidence on the effectiveness of social anxiety apps. A search was conducted on three major mobile platforms: Apple iTunes, Google Play and Windows Store. Apps were included if they addressed social anxiety and used an English language interface. A systematic review of the literature from MEDLINE, EMBASE, PsycINFO, Cochrane, Scopus and Web of Science to identify evidence-based evaluations of social anxiety apps was also undertaken. Of the 1154 apps identified, 38 apps met the inclusion criteria: iTunes (n=18), Google Play (n=16) and Windows Store (n=4). Over 60% of apps were exclusively focused on social anxiety, while the remainder targeted social anxiety and related conditions. Most developers did not provide information on their organisational affiliations or their content source. Most apps used multimedia while 17 apps used text only. Finally, although the systematic review of the literature identified 94 articles, none of which met inclusion criteria. Social anxiety apps have the potential to overcome barriers to accessing treatment; however, none of the apps identified have had studies on their effectiveness published. As the evidence base is lacking, it is therefore not currently possible to recommend their use. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

International Solar-Terrestrial Program Key Parameter Visualization Tool Data: USA_NASA_DDF_ISTP_IM_KP_0161

NASA Technical Reports Server (NTRS)

Ocuna, M. H.; Ogilvie, K. W.; Baker, D. N.; Curtis, S. A.; Fairfield, D. H.; Mish, W. H.

2000-01-01

The Global Geospace Science Program (GGS) is designed to improve greatly the understanding of the flow of energy, mass and momentum in the solar-terrestrial environment with particular emphasis on "Geospace". The Global Geospace Science Program is the US contribution to the International Solar-Terrestrial Physics (ISTP) Science Initiative. This CD-ROM issue describes the WIND and POLAR spacecraft, the scientific experiments carried onboard, the Theoretical and Ground Based investigations which constitute the US Global Geospace Science Program and the ISTP Data Systems which support the data acquisition and analysis effort. The International Solar-Terrestrial Physics Program (ISTP) Key Parameter Visualization Tool (KPVT), provided on the CD-ROM, was developed at the ISTP Science Planning and Operations Facility (SPOF). The KPVT is a generic software package for visualizing the key parameter data produced from all ISTP missions, interactively and simultaneously. The tool is designed to facilitate correlative displays of ISTP data from multiple spacecraft and instruments, and thus the selection of candidate events and data quality control. The software, written in IDL, includes a graphical/widget user interface, and runs on many platforms, including various UNIX workstations, Alpha/Open VMS, Macintosh (680x0 and PowerPC), and PC/Windows NT, Windows 3.1, and Windows 95.

International Solar-Terrestrial Program Key Parameter Visualization Tool Data: USA_NASA_DDF_ISTP_KP_0192

NASA Technical Reports Server (NTRS)

Ocuna, M. H.; Ogilvie, K. W.; Baker, D. N.; Curtis, S. A.; Fairfield, D. H.; Mish, W. H.

2001-01-01

The Global Geospace Science Program (GGS) is designed to improve greatly the understanding of the flow of energy, mass and momentum in the solar-terrestrial environment with particular emphasis on "Geospace". The Global Geospace Science Program is the US contribution to the International Solar-Terrestrial Physics (ISTP) Science Initiative. This CD-ROM issue describes the WIND and POLAR spacecraft, the scientific experiments carried onboard, the Theoretical and Ground Based investigations which constitute the US Global Geospace Science Program and the ISTP Data Systems which support the data acquisition and analysis effort. The International Solar-Terrestrial Physics Program (ISTP) Key Parameter Visualization Tool (KPVT), provided on the CD-ROM, was developed at the ISTP Science Planning and Operations Facility (SPOF). The KPVT is a generic software package for visualizing the key parameter data produced from all ISTP missions, interactively and simultaneously. The tool is designed to facilitate correlative displays of ISTP data from multiple spacecraft and instruments, and thus the selection of candidate events and data quality control. The software, written in IDL, includes a graphical/widget user interface, and runs on many platforms, including various UNIX workstations, Alpha/Open VMS, Macintosh (680x0 and PowerPC), and PC/Windows NT, Windows 3.1, and Windows 95.

International Solar-Terrestrial Program Key Parameter Visualization Tool Data: USA_NASA_DDF_ISTP_KP_0139

NASA Technical Reports Server (NTRS)

Ocuna, M. H.; Ogilvie, K. W.; Baker, D. N.; Curtis, S. A.; Fairfield, D. H.; Mish, W. H.

1999-01-01

The Global Geospace Science Program (GGS) is designed to improve greatly the understanding of the flow of energy, mass and momentum in the solar-terrestrial environment with particular emphasis on "Geospace". The Global Geospace Science Program is the US contribution to the International Solar-Terrestrial Physics (ISTP) Science Initiative. This CD-ROM issue describes the WIND and POLAR spacecraft, the scientific experiments carried onboard, the Theoretical and Ground Based investigations which constitute the US Global Geospace Science Program and the ISTP Data Systems which support the data acquisition and analysis effort. The International Solar-Terrestrial Physics Program (ISTP) Key Parameter Visualization Tool (KPVT), provided on the CD-ROM, was developed at the ISTP Science Planning and Operations Facility (SPOF). The KPVT is a generic software package for visualizing the key parameter data produced from all ISTP missions, interactively and simultaneously. The tool is designed to facilitate correlative displays of ISTP data from multiple spacecraft and instruments, and thus the selection of candidate events and data quality control. The software, written in IDL, includes a graphical/widget user interface, and runs on many platforms, including various UNIX workstations, Alpha/Open VMS, Macintosh (680x0 and PowerPC), and PC/Windows NT, Windows 3.1, and Windows 95.

International Solar-Terrestrial Program Key Parameter Visualization Tool Data: USA_NASA_DDF_ISTP_IM_KP_0185

NASA Technical Reports Server (NTRS)

Ocuna, M. H.; Ogilvie, K. W.; Baker, D. N.; Curtis, S. A.; Fairfield, D. H.; Mish, W. H.

2000-01-01

The Global Geospace Science Program (GGS) is designed to improve greatly the understanding of the flow of energy, mass and momentum in the solar-terrestrial environment with particular emphasis on "Geospace". The Global Geospace Science Program is the US contribution to the International Solar-Terrestrial Physics (ISTP) Science Initiative. This CD-ROM issue describes the WIND and POLAR spacecraft, the scientific experiments carried onboard, the Theoretical and Ground Based investigations which constitute the US Global Geospace Science Program and the ISTP Data Systems which support the data acquisition and analysis effort. The International Solar-Terrestrial Physics Program (ISTP) Key Parameter Visualization Tool (KPVT), provided on the CD-ROM, was developed at the ISTP Science Planning and Operations Facility (SPOF). The KPVT is a generic software package for visualizing the key parameter data produced from all ISTP missions, interactively and simultaneously. The tool is designed to facilitate correlative displays of ISTP data from multiple spacecraft and instruments, and thus the selection of candidate events and data quality control. The software, written in IDL, includes a graphical/widget user interface, and runs on many platforms, including various UNIX workstations, Alpha/Open VMS, Macintosh (680x0 and PowerPC), and PC/Windows NT, Windows 3.1, and Windows 95.

Telescope Array Control System Based on Wireless Touch Screen Platform

NASA Astrophysics Data System (ADS)

Fu, Xia-nan; Huang, Lei; Wei, Jian-yan

2017-10-01

Ground-based Wide Angle Cameras (GMAC) are the ground-based observational facility for the SVOM (Space Variable Object Monitor) astronomical satellite of Sino-French cooperation, and Mini-GWAC is the pathfinder and supplement of GWAC. In the context of the Mini-GWAC telescope array, this paper introduces the design and implementation of a kind of telescope array control system based on the wireless touch screen platform. We describe the development and implementation of the system in detail in terms of control system principle, system hardware structure, software design, experiment, and test etc. The system uses a touch-control PC which is based on the Windows CE system as the upper computer, while the wireless transceiver module and PLC (Programmable Logic Controller) are taken as the system kernel. It has the advantages of low cost, reliable data transmission, and simple operation. And the control system has been applied to the Mini-GWAC successfully.

Electrotunable nanoplasmonic liquid mirror

NASA Astrophysics Data System (ADS)

Montelongo, Yunuen; Sikdar, Debabrata; Ma, Ye; McIntosh, Alastair J. S.; Velleman, Leonora; Kucernak, Anthony R.; Edel, Joshua B.; Kornyshev, Alexei A.

2017-11-01

Recently, there has been a drive to design and develop fully tunable metamaterials for applications ranging from new classes of sensors to superlenses among others. Although advances have been made, tuning and modulating the optical properties in real time remains a challenge. We report on the first realization of a reversible electrotunable liquid mirror based on voltage-controlled self-assembly/disassembly of 16 nm plasmonic nanoparticles at the interface between two immiscible electrolyte solutions. We show that optical properties such as reflectivity and spectral position of the absorption band can be varied in situ within +/-0.5 V. This observed effect is in excellent agreement with theoretical calculations corresponding to the change in average interparticle spacing. This electrochemical fully tunable nanoplasmonic platform can be switched from a highly reflective `mirror' to a transmissive `window' and back again. This study opens a route towards realization of such platforms in future micro/nanoscale electrochemical cells, enabling the creation of tunable plasmonic metamaterials.

jsNMR: an embedded platform-independent NMR spectrum viewer.

PubMed

Vosegaard, Thomas

2015-04-01

jsNMR is a lightweight NMR spectrum viewer written in JavaScript/HyperText Markup Language (HTML), which provides a cross-platform spectrum visualizer that runs on all computer architectures including mobile devices. Experimental (and simulated) datasets are easily opened in jsNMR by (i) drag and drop on a jsNMR browser window, (ii) by preparing a jsNMR file from the jsNMR web site, or (iii) by mailing the raw data to the jsNMR web portal. jsNMR embeds the original data in the HTML file, so a jsNMR file is a self-transforming dataset that may be exported to various formats, e.g. comma-separated values. The main applications of jsNMR are to provide easy access to NMR data without the need for dedicated software installed and to provide the possibility to visualize NMR spectra on web sites. Copyright © 2015 John Wiley & Sons, Ltd.

xQTL workbench: a scalable web environment for multi-level QTL analysis.

PubMed

Arends, Danny; van der Velde, K Joeri; Prins, Pjotr; Broman, Karl W; Möller, Steffen; Jansen, Ritsert C; Swertz, Morris A

2012-04-01

xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator. xQTL workbench runs on all common platforms, including Linux, Mac OS X and Windows. An online demo system, installation guide, tutorials, software and source code are available under the LGPL3 license from http://www.xqtl.org. m.a.swertz@rug.nl.

xQTL workbench: a scalable web environment for multi-level QTL analysis

PubMed Central

Arends, Danny; van der Velde, K. Joeri; Prins, Pjotr; Broman, Karl W.; Möller, Steffen; Jansen, Ritsert C.; Swertz, Morris A.

2012-01-01

Summary: xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator. Availability: xQTL workbench runs on all common platforms, including Linux, Mac OS X and Windows. An online demo system, installation guide, tutorials, software and source code are available under the LGPL3 license from http://www.xqtl.org. Contact: m.a.swertz@rug.nl PMID:22308096

Signal to Noise Studies on Thermographic Data with Fabricated Defects for Defense Structures

NASA Technical Reports Server (NTRS)

Zalameda, Joseph N.; Rajic, Nik; Genest, Marc

2006-01-01

There is a growing international interest in thermal inspection systems for asset life assessment and management of defense platforms. The efficacy of flash thermography is generally enhanced by applying image processing algorithms to the observations of raw temperature. Improving the defect signal to noise ratio (SNR) is of primary interest to reduce false calls and allow for easier interpretation of a thermal inspection image. Several factors affecting defect SNR were studied such as data compression and reconstruction using principal component analysis and time window processing.

Voroprot: an interactive tool for the analysis and visualization of complex geometric features of protein structure.

PubMed

Olechnovic, Kliment; Margelevicius, Mindaugas; Venclovas, Ceslovas

2011-03-01

We present Voroprot, an interactive cross-platform software tool that provides a unique set of capabilities for exploring geometric features of protein structure. Voroprot allows the construction and visualization of the Apollonius diagram (also known as the additively weighted Voronoi diagram), the Apollonius graph, protein alpha shapes, interatomic contact surfaces, solvent accessible surfaces, pockets and cavities inside protein structure. Voroprot is available for Windows, Linux and Mac OS X operating systems and can be downloaded from http://www.ibt.lt/bioinformatics/voroprot/.

McStas 1.7 - a new version of the flexible Monte Carlo neutron scattering package

NASA Astrophysics Data System (ADS)

Willendrup, Peter; Farhi, Emmanuel; Lefmann, Kim

2004-07-01

Current neutron instrumentation is both complex and expensive, and accurate simulation has become essential both for building new instruments and for using them effectively. The McStas neutron ray-trace simulation package is a versatile tool for producing such simulations, developed in collaboration between Risø and ILL. The new version (1.7) has many improvements, among these added support for the popular Microsoft Windows platform. This presentation will demonstrate a selection of the new features through a simulation of the ILL IN6 beamline.

Parallel Climate Data Assimilation PSAS Package

NASA Technical Reports Server (NTRS)

Ding, Hong Q.; Chan, Clara; Gennery, Donald B.; Ferraro, Robert D.

1996-01-01

We have designed and implemented a set of highly efficient and highly scalable algorithms for an unstructured computational package, the PSAS data assimilation package, as demonstrated by detailed performance analysis of systematic runs on up to 512node Intel Paragon. The equation solver achieves a sustained 18 Gflops performance. As the results, we achieved an unprecedented 100-fold solution time reduction on the Intel Paragon parallel platform over the Cray C90. This not only meets and exceeds the DAO time requirements, but also significantly enlarges the window of exploration in climate data assimilations.

The Recognition of Words from Phonemes in Continuous Speech.

DTIC Science & Technology

1981-12-01

C A BAKER UNCLASSIFIED AFIT/GE/EE/810ŝ NL EEEEEEIIEEEEI EEEEEEEEEEEEEE EEEEIIEEEIIEI IIIEEEEIIEIIEE EIEEEEEEEEIIEE IIIEIIEEEEEEEE r- ~. 7 c ~ F IVV...82 06 16 011 AFIT/GE/EE/ 81 D -9 THE RECOGNITION OF WORDS FROM PHONEMES IN CONTINUOUS SPEECH THESIS AFIT/GE/EE/81D-9 Claude A. Baker Captain USAF...33. OU Qbey 14. ZX zoo 34. UX foot 15. SH 5h e 35. UU b.Qt 16. ZH azure 36. UH up 17. MX me 37. UH about 18. NX no 38. ER woQrd 19. NG sinkg 39. XX NA

METEOSPACE, solar monitoring and space weather at Calern observatory

NASA Astrophysics Data System (ADS)

Corbard, T.; Malherbe, J.-M.; Crussaire, D.; Morand, F.; Ruty, F.; Biree, L.; Aboudarham, J.; Fuller, N.; Renaud, C.; Meftah, M.

2016-12-01

METEOSPACE is a new partnership project between the Paris Observatory (OP), the Observatoire de la Côte d'Azur (OCA), the French Air Force and a service company (LUNA technology) for the development and operation of a set of small telescopes Hα / Ca II K / Ca II H / G band to be installed at on the Calern plateau (OCA). The objective is to monitor solar activity for both research and its applications in space weather through continuous optical observations of the dynamic phenomena that are visible in the chromosphere: eruptions, destabilization of the filaments triggering coronal mass ejections and associated Moreton waves.

VizieR Online Data Catalog: AMBRE project. FEROS archived spectra (Worley+, 2012)

NASA Astrophysics Data System (ADS)

Worley, C. C.; de Laverny, P.; Recio-Blanco, A.; Hill, V.; Bijaoui, A.; Ordenovic, C.

2017-11-01

This first release concerns the FEROS data collected from 2005, October to 2009, December. The spectra were reduced by ESO with the corresponding automatic pipeline and then sent to the Observatoire de la Cote d'Azur (OCA, Nice) for ingestion into a dedicated pipeline (see paper). All FEROS spectra cover the domain 350nm-920nm at a resolution of about 48000. Before their ingestion into MATISSE, these spectra have been convolved at a lower resolution (Δλ=0.33Å), sliced and resampled (total number of pixels = 11890). (1 data file).

Simultaneous dual modality optical and MR imaging of mouse dorsal skin-fold window chamber

NASA Astrophysics Data System (ADS)

Salek, Mir Farrokh; Pagel, Mark D.; Gmitro, Arthur F.

2011-02-01

Optical imaging and MRI have both been used extensively to study tumor microenvironment. The two imaging modalities are complementary and can be used to cross-validate one another for specific measurements. We have developed a modular platform that is capable of doing optical microscopy inside an MRI instrument. To do this, an optical relay system transfers the image to outside of the MR bore to a commercial grade CCD camera. This enables simultaneous optical and MR imaging of the same tissue and thus creates the ideal situation for comparative or complementary studies using both modalities. Initial experiments have been done using GFP labeled prostate cancer cells implanted in mouse dorsal skin fold window chamber. Vascular hemodynamics and vascular permeability were studied using our imaging system. Towards this goal, we developed a dual MR-Optical contrast agent by labeling BSA with both Gd-DTPA and Alexa Fluor. Overall system design and results of these preliminary vascular studies are presented.

On-chip plasmon-induced transparency based on plasmonic coupled nanocavities

PubMed Central

Zhu, Yu; Hu, Xiaoyong; Yang, Hong; Gong, Qihuang

2014-01-01

On-chip plasmon-induced transparency offers the possibility of realization of ultrahigh-speed information processing chips. Unfortunately, little experimental progress has been made to date because it is difficult to obtain on-chip plasmon-induced transparency using only a single meta-molecule in plasmonic circuits. Here, we report a simple and efficient strategy to realize on-chip plasmon-induced transparency in a nanoscale U-shaped plasmonic waveguide side-coupled nanocavity pair. High tunability in the transparency window is achieved by covering the pair with different organic polymer layers. It is possible to realize ultrafast all-optical tunability based on pump light-induced refractive index change of a graphene cover layer. Compared with previous reports, the overall feature size of the plasmonic nanostructure is reduced by more than three orders of magnitude, while ultrahigh tunability of the transparency window is maintained. This work also provides a superior platform for the study of the various physical effects and phenomena of nonlinear optics and quantum optics. PMID:24435059

On-chip plasmon-induced transparency based on plasmonic coupled nanocavities.

PubMed

Zhu, Yu; Hu, Xiaoyong; Yang, Hong; Gong, Qihuang

2014-01-17

On-chip plasmon-induced transparency offers the possibility of realization of ultrahigh-speed information processing chips. Unfortunately, little experimental progress has been made to date because it is difficult to obtain on-chip plasmon-induced transparency using only a single meta-molecule in plasmonic circuits. Here, we report a simple and efficient strategy to realize on-chip plasmon-induced transparency in a nanoscale U-shaped plasmonic waveguide side-coupled nanocavity pair. High tunability in the transparency window is achieved by covering the pair with different organic polymer layers. It is possible to realize ultrafast all-optical tunability based on pump light-induced refractive index change of a graphene cover layer. Compared with previous reports, the overall feature size of the plasmonic nanostructure is reduced by more than three orders of magnitude, while ultrahigh tunability of the transparency window is maintained. This work also provides a superior platform for the study of the various physical effects and phenomena of nonlinear optics and quantum optics.

A quantum light-emitting diode for the standard telecom window around 1,550 nm.

PubMed

Müller, T; Skiba-Szymanska, J; Krysa, A B; Huwer, J; Felle, M; Anderson, M; Stevenson, R M; Heffernan, J; Ritchie, D A; Shields, A J

2018-02-28

Single photons and entangled photon pairs are a key resource of many quantum secure communication and quantum computation protocols, and non-Poissonian sources emitting in the low-loss wavelength region around 1,550 nm are essential for the development of fibre-based quantum network infrastructure. However, reaching this wavelength window has been challenging for semiconductor-based quantum light sources. Here we show that quantum dot devices based on indium phosphide are capable of electrically injected single photon emission in this wavelength region. Using the biexciton cascade mechanism, they also produce entangled photons with a fidelity of 87 ± 4%, sufficient for the application of one-way error correction protocols. The material system further allows for entangled photon generation up to an operating temperature of 93 K. Our quantum photon source can be directly integrated with existing long distance quantum communication and cryptography systems, and provides a promising material platform for developing future quantum network hardware.

Fabrication challenges associated with conformal optics

NASA Astrophysics Data System (ADS)

Schaefer, John; Eichholtz, Richard A.; Sulzbach, Frank C.

2001-09-01

A conformal optic is typically an optical window that conforms smoothly to the external shape of a system platform to improve aerodynamics. Conformal optics can be on-axis, such as an ogive missile dome, or off-axis, such as in a free form airplane wing. A common example of conformal optics is the automotive head light window that conforms to the body of the car aerodynamics and aesthetics. The unusual shape of conformal optics creates tremendous challenges for design, manufacturing, and testing. This paper will discuss fabrication methods that have been successfully demonstrated to produce conformal missile domes and associated wavefront corrector elements. It will identify challenges foreseen with more complex free-form configurations. Work presented in this paper was directed by the Precision Conformal Optics Consortium (PCOT). PCOT is comprised of both industrial and academic members who teamed to develop and demonstrate conformal optical systems suitable for insertion into future military programs. The consortium was funded under DARPA agreement number MDA972-96-9-08000.

MAVIS III -- A Windows 95/NT Upgrade

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hardwick, M.F.

1997-12-01

MAVIS (Modeling and Analysis of Explosive Valve Interactions) is a computer program that simulates operation of explosively actuated valve. MAVIS was originally written in Fortran in the mid 1970`s and was primarily run on the Sandia Vax computers in use through the early 1990`s. During the mid to late 1980`s MAVIS was upgraded to include the effects of plastic deformation and it became MAVIS II. When the Vax computers were retired, the Gas Transfer System (GTS) Development Department ported the code to the Macintosh and PC platforms, where it ran as a simple console application. All graphical output was lostmore » during these ports. GTS code developers recently completed an upgrade that provides a Windows 95/NT MAVIS application and restores all of the original graphical output. This upgrade is called MAVIS III version 1.0. This report serves both as a user`s manual for MAVIS III v 1.0 and as a general software development reference.« less

General Mission Analysis Tool (GMAT) Architectural Specification. Draft

NASA Technical Reports Server (NTRS)

Hughes, Steven P.; Conway, Darrel, J.

2007-01-01

Early in 2002, Goddard Space Flight Center (GSFC) began to identify requirements for the flight dynamics software needed to fly upcoming missions that use formations of spacecraft to collect data. These requirements ranged from low level modeling features to large scale interoperability requirements. In 2003 we began work on a system designed to meet these requirement; this system is GMAT. The General Mission Analysis Tool (GMAT) is a general purpose flight dynamics modeling tool built on open source principles. The GMAT code is written in C++, and uses modern C++ constructs extensively. GMAT can be run through either a fully functional Graphical User Interface (GUI) or as a command line program with minimal user feedback. The system is built and runs on Microsoft Windows, Linux, and Macintosh OS X platforms. The GMAT GUI is written using wxWidgets, a cross platform library of components that streamlines the development and extension of the user interface Flight dynamics modeling is performed in GMAT by building components that represent the players in the analysis problem that is being modeled. These components interact through the sequential execution of instructions, embodied in the GMAT Mission Sequence. A typical Mission Sequence will model the trajectories of a set of spacecraft evolving over time, calculating relevant parameters during this propagation, and maneuvering individual spacecraft to maintain a set of mission constraints as established by the mission analyst. All of the elements used in GMAT for mission analysis can be viewed in the GMAT GUI or through a custom scripting language. Analysis problems modeled in GMAT are saved as script files, and these files can be read into GMAT. When a script is read into the GMAT GUI, the corresponding user interface elements are constructed in the GMAT GUI. The GMAT system was developed from the ground up to run in a platform agnostic environment. The source code compiles on numerous different platforms, and is regularly exercised running on Windows, Linux and Macintosh computers by the development and analysis teams working on the project. The system can be run using either a graphical user interface, written using the open source wxWidgets framework, or from a text console. The GMAT source code was written using open source tools. GSFC has released the code using the NASA open source license.

A methodological, task-based approach to Procedure-Specific Simulations training.

PubMed

Setty, Yaki; Salzman, Oren

2016-12-01

Procedure-Specific Simulations (PSS) are 3D realistic simulations that provide a platform to practice complete surgical procedures in a virtual-reality environment. While PSS have the potential to improve surgeons' proficiency, there are no existing standards or guidelines for PSS development in a structured manner. We employ a unique platform inspired by game design to develop virtual reality simulations in three dimensions of urethrovesical anastomosis during radical prostatectomy. 3D visualization is supported by a stereo vision, providing a fully realistic view of the simulation. The software can be executed for any robotic surgery platform. Specifically, we tested the simulation under windows environment on the RobotiX Mentor. Using urethrovesical anastomosis during radical prostatectomy simulation as a representative example, we present a task-based methodological approach to PSS training. The methodology provides tasks in increasing levels of difficulty from a novice level of basic anatomy identification, to an expert level that permits testing new surgical approaches. The modular methodology presented here can be easily extended to support more complex tasks. We foresee this methodology as a tool used to integrate PSS as a complementary training process for surgical procedures.

Immersion and dry scanner extensions for sub-10nm production nodes

NASA Astrophysics Data System (ADS)

Weichselbaum, Stefan; Bornebroek, Frank; de Kort, Toine; Droste, Richard; de Graaf, Roelof F.; van Ballegoij, Rob; Botter, Herman; McLaren, Matthew G.; de Boeij, Wim P.

2015-03-01

Progressing towards the 10nm and 7nm imaging node, pattern-placement and layer-to-layer overlay requirements keep on scaling down and drives system improvements in immersion (ArFi) and dry (ArF/KrF) scanners. A series of module enhancements in the NXT platform have been introduced; among others, the scanner is equipped with exposure stages with better dynamics and thermal control. Grid accuracy improvements with respect to calibration, setup, stability, and layout dependency tighten MMO performance and enable mix and match scanner operation. The same platform improvements also benefit focus control. Improvements in detectability and reproducibility of low contrast alignment marks enhance the alignment solution window for 10nm logic processes and beyond. The system's architecture allows dynamic use of high-order scanner optimization based on advanced actuators of projection lens and scanning stages. This enables a holistic optimization approach for the scanner, the mask, and the patterning process. Productivity scanner design modifications esp. stage speeds and optimization in metrology schemes provide lower layer costs for customers using immersion lithography as well as conventional dry technology. Imaging, overlay, focus, and productivity data is presented, that demonstrates 10nm and 7nm node litho-capability for both (immersion & dry) platforms.

ScaMo: Realisation of an OO-functional DSL for cross platform mobile applications development

NASA Astrophysics Data System (ADS)

Macos, Dragan; Solymosi, Andreas

2013-10-01

The software market is dynamically changing: the Internet is going mobile, the software applications are shifting from the desktop hardware onto the mobile devices. The largest markets are the mobile applications for iOS, Android and Windows Phone and for the purpose the typical programming languages include Objective-C, Java and C ♯. The realization of the native applications implies the integration of the developed software into the environments of mentioned mobile operating systems to enable the access to different hardware components of the devices: GPS module, display, GSM module, etc. This paper deals with the definition and possible implementation of an environment for the automatic application generation for multiple mobile platforms. It is based on a DSL for mobile application development, which includes the programming language Scala and a DSL defined in Scala. As part of a multi-stage cross-compiling algorithm, this language is translated into the language of the affected mobile platform. The advantage of our method lies in the expressiveness of the defined language and the transparent source code translation between different languages, which implies, for example, the advantages of debugging and development of the generated code.

CLIPS 6.0 - C LANGUAGE INTEGRATED PRODUCTION SYSTEM, VERSION 6.0 (UNIX VERSION)

NASA Technical Reports Server (NTRS)

Donnell, B.

1994-01-01

CLIPS, the C Language Integrated Production System, is a complete environment for developing expert systems -- programs which are specifically intended to model human expertise or knowledge. It is designed to allow artificial intelligence research, development, and delivery on conventional computers. CLIPS 6.0 provides a cohesive tool for handling a wide variety of knowledge with support for three different programming paradigms: rule-based, object-oriented, and procedural. Rule-based programming allows knowledge to be represented as heuristics, or "rules-of-thumb" which specify a set of actions to be performed for a given situation. Object-oriented programming allows complex systems to be modeled as modular components (which can be easily reused to model other systems or create new components). The procedural programming capabilities provided by CLIPS 6.0 allow CLIPS to represent knowledge in ways similar to those allowed in languages such as C, Pascal, Ada, and LISP. Using CLIPS 6.0, one can develop expert system software using only rule-based programming, only object-oriented programming, only procedural programming, or combinations of the three. CLIPS provides extensive features to support the rule-based programming paradigm including seven conflict resolution strategies, dynamic rule priorities, and truth maintenance. CLIPS 6.0 supports more complex nesting of conditional elements in the if portion of a rule ("and", "or", and "not" conditional elements can be placed within a "not" conditional element). In addition, there is no longer a limitation on the number of multifield slots that a deftemplate can contain. The CLIPS Object-Oriented Language (COOL) provides object-oriented programming capabilities. Features supported by COOL include classes with multiple inheritance, abstraction, encapsulation, polymorphism, dynamic binding, and message passing with message-handlers. CLIPS 6.0 supports tight integration of the rule-based programming features of CLIPS with COOL (that is, a rule can pattern match on objects created using COOL). CLIPS 6.0 provides the capability to define functions, overloaded functions, and global variables interactively. In addition, CLIPS can be embedded within procedural code, called as a subroutine, and integrated with languages such as C, FORTRAN and Ada. CLIPS can be easily extended by a user through the use of several well-defined protocols. CLIPS provides several delivery options for programs including the ability to generate stand alone executables or to load programs from text or binary files. CLIPS 6.0 provides support for the modular development and execution of knowledge bases with the defmodule construct. CLIPS modules allow a set of constructs to be grouped together such that explicit control can be maintained over restricting the access of the constructs by other modules. This type of control is similar to global and local scoping used in languages such as C or Ada. By restricting access to deftemplate and defclass constructs, modules can function as blackboards, permitting only certain facts and instances to be seen by other modules. Modules are also used by rules to provide execution control. The CRSV (Cross-Reference, Style, and Verification) utility included with previous version of CLIPS is no longer supported. The capabilities provided by this tool are now available directly within CLIPS 6.0 to aid in the development, debugging, and verification of large rule bases. COSMIC offers four distribution versions of CLIPS 6.0: UNIX (MSC-22433), VMS (MSC-22434), MACINTOSH (MSC-22429), and IBM PC (MSC-22430). Executable files, source code, utilities, documentation, and examples are included on the program media. All distribution versions include identical source code for the command line version of CLIPS 6.0. This source code should compile on any platform with an ANSI C compiler. Each distribution version of CLIPS 6.0, except that for the Macintosh platform, includes an executable for the command line version. For the UNIX version of CLIPS 6.0, the command line interface has been successfully implemented on a Sun4 running SunOS, a DECstation running DEC RISC ULTRIX, an SGI Indigo Elan running IRIX, a DEC Alpha AXP running OSF/1, and an IBM RS/6000 running AIX. Command line interface executables are included for Sun4 computers running SunOS 4.1.1 or later and for the DEC RISC ULTRIX platform. The makefiles may have to be modified slightly to be used on other UNIX platforms. The UNIX, Macintosh, and IBM PC versions of CLIPS 6.0 each have a platform specific interface. Source code, a makefile, and an executable for the Windows 3.1 interface version of CLIPS 6.0 are provided only on the IBM PC distribution diskettes. Source code, a makefile, and an executable for the Macintosh interface version of CLIPS 6.0 are provided only on the Macintosh distribution diskettes. Likewise, for the UNIX version of CLIPS 6.0, only source code and a makefile for an X-Windows interface are provided. The X-Windows interface requires MIT's X Window System, Version 11, Release 4 (X11R4), the Athena Widget Set, and the Xmu library. The source code for the Athena Widget Set is provided on the distribution medium. The X-Windows interface has been successfully implemented on a Sun4 running SunOS 4.1.2 with the MIT distribution of X11R4 (not OpenWindows), an SGI Indigo Elan running IRIX 4.0.5, and a DEC Alpha AXP running OSF/1 1.2. The VAX version of CLIPS 6.0 comes only with the generic command line interface. ASCII makefiles for the command line version of CLIPS are provided on all the distribution media for UNIX, VMS, and DOS. Four executables are provided with the IBM PC version: a windowed interface executable for Windows 3.1 built using Borland C++ v3.1, an editor for use with the windowed interface, a command line version of CLIPS for Windows 3.1, and a 386 command line executable for DOS built using Zortech C++ v3.1. All four executables are capable of utilizing extended memory and require an 80386 CPU or better. Users needing an 8086/8088 or 80286 executable must recompile the CLIPS source code themselves. Users who wish to recompile the DOS executable using Borland C++ or MicroSoft C must use a DOS extender program to produce an executable capable of using extended memory. The version of CLIPS 6.0 for IBM PC compatibles requires DOS v3.3 or later and/or Windows 3.1 or later. It is distributed on a set of three 1.4Mb 3.5 inch diskettes. A hard disk is required. The Macintosh version is distributed in compressed form on two 3.5 inch 1.4Mb Macintosh format diskettes, and requires System 6.0.5, or higher, and 1Mb RAM. The version for DEC VAX/VMS is available in VAX BACKUP format on a 1600 BPI 9-track magnetic tape (standard distribution medium) or a TK50 tape cartridge. The UNIX version is distributed in UNIX tar format on a .25 inch streaming magnetic tape cartridge (Sun QIC-24). For the UNIX version, alternate distribution media and formats are available upon request. The CLIPS 6.0 documentation includes a User's Guide and a three volume Reference Manual consisting of Basic and Advanced Programming Guides and an Interfaces Guide. An electronic version of the documentation is provided on the distribution medium for each version: in MicroSoft Word format for the Macintosh and PC versions of CLIPS, and in both PostScript format and MicroSoft Word for Macintosh format for the UNIX and DEC VAX versions of CLIPS. CLIPS was developed in 1986 and Version 6.0 was released in 1993.

CLIPS 6.0 - C LANGUAGE INTEGRATED PRODUCTION SYSTEM, VERSION 6.0 (IBM PC VERSION)

NASA Technical Reports Server (NTRS)

Donnell, B.

1994-01-01

CLIPS, the C Language Integrated Production System, is a complete environment for developing expert systems -- programs which are specifically intended to model human expertise or knowledge. It is designed to allow artificial intelligence research, development, and delivery on conventional computers. CLIPS 6.0 provides a cohesive tool for handling a wide variety of knowledge with support for three different programming paradigms: rule-based, object-oriented, and procedural. Rule-based programming allows knowledge to be represented as heuristics, or "rules-of-thumb" which specify a set of actions to be performed for a given situation. Object-oriented programming allows complex systems to be modeled as modular components (which can be easily reused to model other systems or create new components). The procedural programming capabilities provided by CLIPS 6.0 allow CLIPS to represent knowledge in ways similar to those allowed in languages such as C, Pascal, Ada, and LISP. Using CLIPS 6.0, one can develop expert system software using only rule-based programming, only object-oriented programming, only procedural programming, or combinations of the three. CLIPS provides extensive features to support the rule-based programming paradigm including seven conflict resolution strategies, dynamic rule priorities, and truth maintenance. CLIPS 6.0 supports more complex nesting of conditional elements in the if portion of a rule ("and", "or", and "not" conditional elements can be placed within a "not" conditional element). In addition, there is no longer a limitation on the number of multifield slots that a deftemplate can contain. The CLIPS Object-Oriented Language (COOL) provides object-oriented programming capabilities. Features supported by COOL include classes with multiple inheritance, abstraction, encapsulation, polymorphism, dynamic binding, and message passing with message-handlers. CLIPS 6.0 supports tight integration of the rule-based programming features of CLIPS with COOL (that is, a rule can pattern match on objects created using COOL). CLIPS 6.0 provides the capability to define functions, overloaded functions, and global variables interactively. In addition, CLIPS can be embedded within procedural code, called as a subroutine, and integrated with languages such as C, FORTRAN and Ada. CLIPS can be easily extended by a user through the use of several well-defined protocols. CLIPS provides several delivery options for programs including the ability to generate stand alone executables or to load programs from text or binary files. CLIPS 6.0 provides support for the modular development and execution of knowledge bases with the defmodule construct. CLIPS modules allow a set of constructs to be grouped together such that explicit control can be maintained over restricting the access of the constructs by other modules. This type of control is similar to global and local scoping used in languages such as C or Ada. By restricting access to deftemplate and defclass constructs, modules can function as blackboards, permitting only certain facts and instances to be seen by other modules. Modules are also used by rules to provide execution control. The CRSV (Cross-Reference, Style, and Verification) utility included with previous version of CLIPS is no longer supported. The capabilities provided by this tool are now available directly within CLIPS 6.0 to aid in the development, debugging, and verification of large rule bases. COSMIC offers four distribution versions of CLIPS 6.0: UNIX (MSC-22433), VMS (MSC-22434), MACINTOSH (MSC-22429), and IBM PC (MSC-22430). Executable files, source code, utilities, documentation, and examples are included on the program media. All distribution versions include identical source code for the command line version of CLIPS 6.0. This source code should compile on any platform with an ANSI C compiler. Each distribution version of CLIPS 6.0, except that for the Macintosh platform, includes an executable for the command line version. For the UNIX version of CLIPS 6.0, the command line interface has been successfully implemented on a Sun4 running SunOS, a DECstation running DEC RISC ULTRIX, an SGI Indigo Elan running IRIX, a DEC Alpha AXP running OSF/1, and an IBM RS/6000 running AIX. Command line interface executables are included for Sun4 computers running SunOS 4.1.1 or later and for the DEC RISC ULTRIX platform. The makefiles may have to be modified slightly to be used on other UNIX platforms. The UNIX, Macintosh, and IBM PC versions of CLIPS 6.0 each have a platform specific interface. Source code, a makefile, and an executable for the Windows 3.1 interface version of CLIPS 6.0 are provided only on the IBM PC distribution diskettes. Source code, a makefile, and an executable for the Macintosh interface version of CLIPS 6.0 are provided only on the Macintosh distribution diskettes. Likewise, for the UNIX version of CLIPS 6.0, only source code and a makefile for an X-Windows interface are provided. The X-Windows interface requires MIT's X Window System, Version 11, Release 4 (X11R4), the Athena Widget Set, and the Xmu library. The source code for the Athena Widget Set is provided on the distribution medium. The X-Windows interface has been successfully implemented on a Sun4 running SunOS 4.1.2 with the MIT distribution of X11R4 (not OpenWindows), an SGI Indigo Elan running IRIX 4.0.5, and a DEC Alpha AXP running OSF/1 1.2. The VAX version of CLIPS 6.0 comes only with the generic command line interface. ASCII makefiles for the command line version of CLIPS are provided on all the distribution media for UNIX, VMS, and DOS. Four executables are provided with the IBM PC version: a windowed interface executable for Windows 3.1 built using Borland C++ v3.1, an editor for use with the windowed interface, a command line version of CLIPS for Windows 3.1, and a 386 command line executable for DOS built using Zortech C++ v3.1. All four executables are capable of utilizing extended memory and require an 80386 CPU or better. Users needing an 8086/8088 or 80286 executable must recompile the CLIPS source code themselves. Users who wish to recompile the DOS executable using Borland C++ or MicroSoft C must use a DOS extender program to produce an executable capable of using extended memory. The version of CLIPS 6.0 for IBM PC compatibles requires DOS v3.3 or later and/or Windows 3.1 or later. It is distributed on a set of three 1.4Mb 3.5 inch diskettes. A hard disk is required. The Macintosh version is distributed in compressed form on two 3.5 inch 1.4Mb Macintosh format diskettes, and requires System 6.0.5, or higher, and 1Mb RAM. The version for DEC VAX/VMS is available in VAX BACKUP format on a 1600 BPI 9-track magnetic tape (standard distribution medium) or a TK50 tape cartridge. The UNIX version is distributed in UNIX tar format on a .25 inch streaming magnetic tape cartridge (Sun QIC-24). For the UNIX version, alternate distribution media and formats are available upon request. The CLIPS 6.0 documentation includes a User's Guide and a three volume Reference Manual consisting of Basic and Advanced Programming Guides and an Interfaces Guide. An electronic version of the documentation is provided on the distribution medium for each version: in MicroSoft Word format for the Macintosh and PC versions of CLIPS, and in both PostScript format and MicroSoft Word for Macintosh format for the UNIX and DEC VAX versions of CLIPS. CLIPS was developed in 1986 and Version 6.0 was released in 1993.

CLIPS 6.0 - C LANGUAGE INTEGRATED PRODUCTION SYSTEM, VERSION 6.0 (MACINTOSH VERSION)

NASA Technical Reports Server (NTRS)

Riley, G.

1994-01-01

CLIPS, the C Language Integrated Production System, is a complete environment for developing expert systems -- programs which are specifically intended to model human expertise or knowledge. It is designed to allow artificial intelligence research, development, and delivery on conventional computers. CLIPS 6.0 provides a cohesive tool for handling a wide variety of knowledge with support for three different programming paradigms: rule-based, object-oriented, and procedural. Rule-based programming allows knowledge to be represented as heuristics, or "rules-of-thumb" which specify a set of actions to be performed for a given situation. Object-oriented programming allows complex systems to be modeled as modular components (which can be easily reused to model other systems or create new components). The procedural programming capabilities provided by CLIPS 6.0 allow CLIPS to represent knowledge in ways similar to those allowed in languages such as C, Pascal, Ada, and LISP. Using CLIPS 6.0, one can develop expert system software using only rule-based programming, only object-oriented programming, only procedural programming, or combinations of the three. CLIPS provides extensive features to support the rule-based programming paradigm including seven conflict resolution strategies, dynamic rule priorities, and truth maintenance. CLIPS 6.0 supports more complex nesting of conditional elements in the if portion of a rule ("and", "or", and "not" conditional elements can be placed within a "not" conditional element). In addition, there is no longer a limitation on the number of multifield slots that a deftemplate can contain. The CLIPS Object-Oriented Language (COOL) provides object-oriented programming capabilities. Features supported by COOL include classes with multiple inheritance, abstraction, encapsulation, polymorphism, dynamic binding, and message passing with message-handlers. CLIPS 6.0 supports tight integration of the rule-based programming features of CLIPS with COOL (that is, a rule can pattern match on objects created using COOL). CLIPS 6.0 provides the capability to define functions, overloaded functions, and global variables interactively. In addition, CLIPS can be embedded within procedural code, called as a subroutine, and integrated with languages such as C, FORTRAN and Ada. CLIPS can be easily extended by a user through the use of several well-defined protocols. CLIPS provides several delivery options for programs including the ability to generate stand alone executables or to load programs from text or binary files. CLIPS 6.0 provides support for the modular development and execution of knowledge bases with the defmodule construct. CLIPS modules allow a set of constructs to be grouped together such that explicit control can be maintained over restricting the access of the constructs by other modules. This type of control is similar to global and local scoping used in languages such as C or Ada. By restricting access to deftemplate and defclass constructs, modules can function as blackboards, permitting only certain facts and instances to be seen by other modules. Modules are also used by rules to provide execution control. The CRSV (Cross-Reference, Style, and Verification) utility included with previous version of CLIPS is no longer supported. The capabilities provided by this tool are now available directly within CLIPS 6.0 to aid in the development, debugging, and verification of large rule bases. COSMIC offers four distribution versions of CLIPS 6.0: UNIX (MSC-22433), VMS (MSC-22434), MACINTOSH (MSC-22429), and IBM PC (MSC-22430). Executable files, source code, utilities, documentation, and examples are included on the program media. All distribution versions include identical source code for the command line version of CLIPS 6.0. This source code should compile on any platform with an ANSI C compiler. Each distribution version of CLIPS 6.0, except that for the Macintosh platform, includes an executable for the command line version. For the UNIX version of CLIPS 6.0, the command line interface has been successfully implemented on a Sun4 running SunOS, a DECstation running DEC RISC ULTRIX, an SGI Indigo Elan running IRIX, a DEC Alpha AXP running OSF/1, and an IBM RS/6000 running AIX. Command line interface executables are included for Sun4 computers running SunOS 4.1.1 or later and for the DEC RISC ULTRIX platform. The makefiles may have to be modified slightly to be used on other UNIX platforms. The UNIX, Macintosh, and IBM PC versions of CLIPS 6.0 each have a platform specific interface. Source code, a makefile, and an executable for the Windows 3.1 interface version of CLIPS 6.0 are provided only on the IBM PC distribution diskettes. Source code, a makefile, and an executable for the Macintosh interface version of CLIPS 6.0 are provided only on the Macintosh distribution diskettes. Likewise, for the UNIX version of CLIPS 6.0, only source code and a makefile for an X-Windows interface are provided. The X-Windows interface requires MIT's X Window System, Version 11, Release 4 (X11R4), the Athena Widget Set, and the Xmu library. The source code for the Athena Widget Set is provided on the distribution medium. The X-Windows interface has been successfully implemented on a Sun4 running SunOS 4.1.2 with the MIT distribution of X11R4 (not OpenWindows), an SGI Indigo Elan running IRIX 4.0.5, and a DEC Alpha AXP running OSF/1 1.2. The VAX version of CLIPS 6.0 comes only with the generic command line interface. ASCII makefiles for the command line version of CLIPS are provided on all the distribution media for UNIX, VMS, and DOS. Four executables are provided with the IBM PC version: a windowed interface executable for Windows 3.1 built using Borland C++ v3.1, an editor for use with the windowed interface, a command line version of CLIPS for Windows 3.1, and a 386 command line executable for DOS built using Zortech C++ v3.1. All four executables are capable of utilizing extended memory and require an 80386 CPU or better. Users needing an 8086/8088 or 80286 executable must recompile the CLIPS source code themselves. Users who wish to recompile the DOS executable using Borland C++ or MicroSoft C must use a DOS extender program to produce an executable capable of using extended memory. The version of CLIPS 6.0 for IBM PC compatibles requires DOS v3.3 or later and/or Windows 3.1 or later. It is distributed on a set of three 1.4Mb 3.5 inch diskettes. A hard disk is required. The Macintosh version is distributed in compressed form on two 3.5 inch 1.4Mb Macintosh format diskettes, and requires System 6.0.5, or higher, and 1Mb RAM. The version for DEC VAX/VMS is available in VAX BACKUP format on a 1600 BPI 9-track magnetic tape (standard distribution medium) or a TK50 tape cartridge. The UNIX version is distributed in UNIX tar format on a .25 inch streaming magnetic tape cartridge (Sun QIC-24). For the UNIX version, alternate distribution media and formats are available upon request. The CLIPS 6.0 documentation includes a User's Guide and a three volume Reference Manual consisting of Basic and Advanced Programming Guides and an Interfaces Guide. An electronic version of the documentation is provided on the distribution medium for each version: in MicroSoft Word format for the Macintosh and PC versions of CLIPS, and in both PostScript format and MicroSoft Word for Macintosh format for the UNIX and DEC VAX versions of CLIPS. CLIPS was developed in 1986 and Version 6.0 was released in 1993.

CLIPS 6.0 - C LANGUAGE INTEGRATED PRODUCTION SYSTEM, VERSION 6.0 (DEC VAX VMS VERSION)

NASA Technical Reports Server (NTRS)

Donnell, B.

1994-01-01

CLIPS, the C Language Integrated Production System, is a complete environment for developing expert systems -- programs which are specifically intended to model human expertise or knowledge. It is designed to allow artificial intelligence research, development, and delivery on conventional computers. CLIPS 6.0 provides a cohesive tool for handling a wide variety of knowledge with support for three different programming paradigms: rule-based, object-oriented, and procedural. Rule-based programming allows knowledge to be represented as heuristics, or "rules-of-thumb" which specify a set of actions to be performed for a given situation. Object-oriented programming allows complex systems to be modeled as modular components (which can be easily reused to model other systems or create new components). The procedural programming capabilities provided by CLIPS 6.0 allow CLIPS to represent knowledge in ways similar to those allowed in languages such as C, Pascal, Ada, and LISP. Using CLIPS 6.0, one can develop expert system software using only rule-based programming, only object-oriented programming, only procedural programming, or combinations of the three. CLIPS provides extensive features to support the rule-based programming paradigm including seven conflict resolution strategies, dynamic rule priorities, and truth maintenance. CLIPS 6.0 supports more complex nesting of conditional elements in the if portion of a rule ("and", "or", and "not" conditional elements can be placed within a "not" conditional element). In addition, there is no longer a limitation on the number of multifield slots that a deftemplate can contain. The CLIPS Object-Oriented Language (COOL) provides object-oriented programming capabilities. Features supported by COOL include classes with multiple inheritance, abstraction, encapsulation, polymorphism, dynamic binding, and message passing with message-handlers. CLIPS 6.0 supports tight integration of the rule-based programming features of CLIPS with COOL (that is, a rule can pattern match on objects created using COOL). CLIPS 6.0 provides the capability to define functions, overloaded functions, and global variables interactively. In addition, CLIPS can be embedded within procedural code, called as a subroutine, and integrated with languages such as C, FORTRAN and Ada. CLIPS can be easily extended by a user through the use of several well-defined protocols. CLIPS provides several delivery options for programs including the ability to generate stand alone executables or to load programs from text or binary files. CLIPS 6.0 provides support for the modular development and execution of knowledge bases with the defmodule construct. CLIPS modules allow a set of constructs to be grouped together such that explicit control can be maintained over restricting the access of the constructs by other modules. This type of control is similar to global and local scoping used in languages such as C or Ada. By restricting access to deftemplate and defclass constructs, modules can function as blackboards, permitting only certain facts and instances to be seen by other modules. Modules are also used by rules to provide execution control. The CRSV (Cross-Reference, Style, and Verification) utility included with previous version of CLIPS is no longer supported. The capabilities provided by this tool are now available directly within CLIPS 6.0 to aid in the development, debugging, and verification of large rule bases. COSMIC offers four distribution versions of CLIPS 6.0: UNIX (MSC-22433), VMS (MSC-22434), MACINTOSH (MSC-22429), and IBM PC (MSC-22430). Executable files, source code, utilities, documentation, and examples are included on the program media. All distribution versions include identical source code for the command line version of CLIPS 6.0. This source code should compile on any platform with an ANSI C compiler. Each distribution version of CLIPS 6.0, except that for the Macintosh platform, includes an executable for the command line version. For the UNIX version of CLIPS 6.0, the command line interface has been successfully implemented on a Sun4 running SunOS, a DECstation running DEC RISC ULTRIX, an SGI Indigo Elan running IRIX, a DEC Alpha AXP running OSF/1, and an IBM RS/6000 running AIX. Command line interface executables are included for Sun4 computers running SunOS 4.1.1 or later and for the DEC RISC ULTRIX platform. The makefiles may have to be modified slightly to be used on other UNIX platforms. The UNIX, Macintosh, and IBM PC versions of CLIPS 6.0 each have a platform specific interface. Source code, a makefile, and an executable for the Windows 3.1 interface version of CLIPS 6.0 are provided only on the IBM PC distribution diskettes. Source code, a makefile, and an executable for the Macintosh interface version of CLIPS 6.0 are provided only on the Macintosh distribution diskettes. Likewise, for the UNIX version of CLIPS 6.0, only source code and a makefile for an X-Windows interface are provided. The X-Windows interface requires MIT's X Window System, Version 11, Release 4 (X11R4), the Athena Widget Set, and the Xmu library. The source code for the Athena Widget Set is provided on the distribution medium. The X-Windows interface has been successfully implemented on a Sun4 running SunOS 4.1.2 with the MIT distribution of X11R4 (not OpenWindows), an SGI Indigo Elan running IRIX 4.0.5, and a DEC Alpha AXP running OSF/1 1.2. The VAX version of CLIPS 6.0 comes only with the generic command line interface. ASCII makefiles for the command line version of CLIPS are provided on all the distribution media for UNIX, VMS, and DOS. Four executables are provided with the IBM PC version: a windowed interface executable for Windows 3.1 built using Borland C++ v3.1, an editor for use with the windowed interface, a command line version of CLIPS for Windows 3.1, and a 386 command line executable for DOS built using Zortech C++ v3.1. All four executables are capable of utilizing extended memory and require an 80386 CPU or better. Users needing an 8086/8088 or 80286 executable must recompile the CLIPS source code themselves. Users who wish to recompile the DOS executable using Borland C++ or MicroSoft C must use a DOS extender program to produce an executable capable of using extended memory. The version of CLIPS 6.0 for IBM PC compatibles requires DOS v3.3 or later and/or Windows 3.1 or later. It is distributed on a set of three 1.4Mb 3.5 inch diskettes. A hard disk is required. The Macintosh version is distributed in compressed form on two 3.5 inch 1.4Mb Macintosh format diskettes, and requires System 6.0.5, or higher, and 1Mb RAM. The version for DEC VAX/VMS is available in VAX BACKUP format on a 1600 BPI 9-track magnetic tape (standard distribution medium) or a TK50 tape cartridge. The UNIX version is distributed in UNIX tar format on a .25 inch streaming magnetic tape cartridge (Sun QIC-24). For the UNIX version, alternate distribution media and formats are available upon request. The CLIPS 6.0 documentation includes a User's Guide and a three volume Reference Manual consisting of Basic and Advanced Programming Guides and an Interfaces Guide. An electronic version of the documentation is provided on the distribution medium for each version: in MicroSoft Word format for the Macintosh and PC versions of CLIPS, and in both PostScript format and MicroSoft Word for Macintosh format for the UNIX and DEC VAX versions of CLIPS. CLIPS was developed in 1986 and Version 6.0 was released in 1993.

OCT imaging of acute vascular changes following mild traumatic brain injury in mice (Conference Presentation)

NASA Astrophysics Data System (ADS)

Chico-Calero, Isabel; Shishkov, Milen; Welt, Jonathan; Blatter, Cedric; Vakoc, Benjamin J.

2016-03-01

While most people recover completely from mild traumatic brain injuries (mTBIs) and concussions, a subset develop lasting neurological disorders. Understanding the complex pathophysiology of these injuries is critical to developing improved prognostic and therapeutic approaches. Multiple studies have shown that the structure and perfusion of brain vessels are altered after mTBI. It is possible that these vascular injuries contribute to or trigger neurodegeneration. Intravital microscopy and mouse models of TBI offer a powerful platform to study the vascular component of mTBI. Because optical coherence tomography based angiography is based on perfusion contrast and is not significantly degraded by vessel leakage or blood brain barrier disruption, it is uniquely suited to studies of brain perfusion in the setting of trauma. However, existing TBI imaging models require surgical exposure of the brain at the time of injury which conflates TBI-related vascular changes with those caused by surgery. In this work, we describe a modified cranial window preparation based on a flexible, transparent polyurethane membrane. Impact injuries were delivered directly through this membrane, and imaging was performed immediately after injury without the need for additional surgical procedures. Using this model, we demonstrate that mTBI induces a transient cessation of flow in the capillaries and smaller vessels near the injury point. Reperfusion is observed in all animals within 3 hours of injury. This work describes new insight into the transient vascular changes induced by mTBI, and demonstrates more broadly the utility of the OCT/polyurethane window model platform in preclinical studies of mTBI.

[Patient education: state of the art of the programs in the region of Provence-Alpes-Côte d'Azur in 2008 before the publication of official documents relative to the authorizations of the Regional Health Agency (ARS)].

PubMed

Parron, S; Gentile, S; Enel, P; Benhaïm, L; Ferrandino, J; Bentz, L; Sambuc, R

2013-02-01

At the request of the Hospitalization Regional Agency (ARH)--in the context of the 2007-2011 plan aimed at improving the quality of life for patients affected by chronic diseases--the purpose of this work was to draw up a clear assessment of the 2008 Therapeutic Education programmes in the Provence-Alpes-Côte d'Azur (PACA) region. The study was carried out before the publication of the therapeutic education statutory orders and ARS (regional health agency) authorizations. Cross-sectional study, carried out in the three sectors of medical management in the region--namely health-care institutions, ambulatory structures and health networks--made it possible to identify, first, which structures had actually launched therapeutic education programmes and then, how the procedures had been designed and set up. Among all the medical structures investigated, the study has listed 491 programmes, heterogeneously located throughout the PACA region. These programmes primarily target diabetes, respiratory and cardiovascular diseases. Their main objectives are the patients' quality of life, adherence to treatment and protective health behaviour (health improvement). The hospitalization sector programmes preferentially target the 30 to 60 years old, whereas the ambulatory and health networks programmes are more inclined to target the over 60 years old part of the population. More than 50% of the professionals involved in the programmes have never benefited from a specific training concerning the patients' therapeutic education. This study has pointed out a great number of important aspects which need drastic improvement in terms of therapeutic education organization - the involvement and training of health professionals, for instance. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Biodegradation of Azure-B dye by Serratia liquefaciens and its validation by phytotoxicity, genotoxicity and cytotoxicity studies.

PubMed

Haq, Izharul; Raj, Abhay; Markandeya

2018-04-01

The azo dyes in textile industry are a major source of environmental pollution and cause serious threat to aquatic flora and fauna. The present study aims to evaluate the potential of previously isolated lignin peroxidase (LiP) enzyme producing Serratia liquefaciens in degradation of Azure-B (AB) dye. S. liquefaciens showed rapid decolourisation of AB dye (100 mg L -1 ) in mineral salt medium (MSM) supplemented with 0.2% glucose and yeast extract, and more than 90% dye decolourisation was observed at 48 h when incubated at 30 °C. Decolourisation conditions were optimized by Response Surface Methodology (RSM) using Box-Behnken Designs (BBD). The dye degradation was further confirmed by ATR-FTIR and GC-MS analysis. Toxicological studies of untreated (UT) and bacterial treated (BT) AB dye solutions were studied by using phytotoxicity, genotoxicity and cytotoxicity endpoints. Phytotoxicity assay using Vigna radiata indicated that bacterial treatment led to detoxification of AB dye. Genotoxicity assay with Allium cepa showed that pure AB dye solutions significantly reduced mitotic index (MI) and induced various chromosomal abnormalities (CAs) like c-mitosis, stickiness, chromosome break, anaphase bridges, vagrant chromosomes and binucleated and micronucleated cell in the root tip cells, whereas, bacterial treated solutions induced relatively less genotoxicity in nature. Improved cell survivability (%) was also noted in kidney cell line (NRK-52E) after S. liquefaciens treated dye solutions than the pure dye solutions. The findings suggest that S. liquefaciens could be a potential bacterium for azo dye degradation, as it is effective in lowering of toxic effects of AB dye. Copyright © 2018 Elsevier Ltd. All rights reserved.

Differences in Relative Hippocampus Volume and Number of Hippocampus Neurons among Five Corvid Species

PubMed Central

Gould, Kristy L.; Gilbertson, Karl E.; Seyfer, Abigail L.; Brantner, Rose M.; Hrvol, Andrew J.; Kamil, Alan C.; Nelson, Joseph C.

2016-01-01

The relative size of the avian hippocampus (Hp) has been shown to be related to spatial memory and food storing in two avian families, the parids and corvids. Basil et al. [Brain Behav Evol 1996;47: 156-164] examined North American food-storing birds in the corvid family and found that Clark's nutcrackers had a larger relative Hp than pinyon jays and Western scrub jays. These results correlated with the nutcracker's better performance on most spatial memory tasks and their strong reliance on stored food in the wild. However, Pravosudov and de Kort [Brain Behav Evol 67 (2006), 1-9] raised questions about the methodology used in the 1996 study, specifically the use of paraffin as an embedding material and recalculation for shrinkage. Therefore, we measured relative Hp volume using gelatin as the embedding material in four North American species of food-storing corvids (Clark's nutcrackers, pinyon jays, Western scrub jays and blue jays) and one Eurasian corvid that stores little to no food (azure-winged magpies). Although there was a significant overall effect of species on relative Hp volume among the five species, subsequent tests found only one pairwise difference, blue jays having a larger Hp than the azure-winged magpies. We also examined the relative size of the septum in the five species. Although Shiflett et al. [J Neurobiol 51 (2002), 215-222] found a difference in relative septum volume amongst three species of parids that correlated with storing food, we did not find significant differences amongst the five species in relative septum. Finally, we calculated the number of neurons in the Hp relative to body mass in the five species and found statistically significant differences, some of which are in accord with the adaptive specialization hypothesis and some are not. PMID:23364270

A stochastic Forest Fire Model for future land cover scenarios assessment

NASA Astrophysics Data System (ADS)

Fiorucci, P.; Holmes, T.; Gaetani, F.; D'Andrea, M.

2009-04-01

Land cover change and forest fire interaction under climate and socio-economics changes, is one of the main issues of the 21th century. The capability of defining future scenarios of land cover and fire regime allow forest managers to better understand the best actions to be carried out and their long term effects. In this paper a new methodology for land cover change simulations under climate change and fire disturbance is presented and discussed. The methodology is based on the assumption that forest fires exhibits power law frequency-area distribution. The well known Forest Fire Model (FFM), which is an example of self organized criticality, is able to reproduce this behavior. Starting from this observation, a modified version of the FFM has been developed. The new model, called Modified Forest Fire Model (MFFM) introduces several new features. A stochastic model for vegetation growth and regrowth after fire occurrence has been implemented for different kind of vegetations. In addition, a stochastic fire propagation model taking into account topography and vegetation cover has been introduced. The MFFM has been developed with the purpose of estimating vegetation cover changes and fire regimes over a time windows of many years for a given spatial region. Two different case studies have been carried out. The first case study is related with Liguria (Italy), a region of 5400 km2 lying between the Cote d'Azur, France, and Tuscany, Italy, on the northwest coast of the Tyrrhenian Sea. This region is characterized by Mediterranean fire regime. The second case study has been carried out in California (Florida) on a region having similar area and characterized by similar climate conditions. In both cases the model well represents the actual fire regime in terms of power law parameters proving interesting results about future land cover scenarios under climate, land use and socio-economics change.

Kinect Technology Game Play to Mimic Quake Catcher Network (QCN) Sensor Deployment During a Rapid Aftershock Mobilization Program (RAMP)

NASA Astrophysics Data System (ADS)

Kilb, D. L.; Yang, A.; Rohrlick, D.; Cochran, E. S.; Lawrence, J.; Chung, A. I.; Neighbors, C.; Choo, Y.

2011-12-01

The Kinect technology allows for hands-free game play, greatly increasing the accessibility of gaming for those uncomfortable using controllers. How it works is the Kinect camera transmits invisible near-infrared light and measures its "time of flight" to reflect off an object, allowing it to distinguish objects within 1 centimeter in depth and 3 mm in height and width. The middleware can also respond to body gestures and voice commands. Here, we use the Kinect Windows SDK software to create a game that mimics how scientists deploy seismic instruments following a large earthquake. The educational goal of the game is to allow the players to explore 3D space as they learn about the Quake Catcher Network's (QCN) Rapid Aftershock Mobilization Program (RAMP). Many of the scenarios within the game are taken from factual RAMP experiences. To date, only the PC platform (or a Mac running PC emulator software) is available for use, but we hope to move to other platforms (e.g., Xbox 360, iPad, iPhone) as they become available. The game is written in programming language C# using Microsoft XNA and Visual Studio 2010, graphic shading is added using High Level Shader Language (HLSL), and rendering is produced using XNA's graphics libraries. Key elements of the game include selecting sensor locations, adequately installing the sensor, and monitoring the incoming data. During game play aftershocks can occur unexpectedly, as can other problems that require attention (e.g., power outages, equipment failure, and theft). The player accrues points for quickly deploying the first sensor (recording as many initial aftershocks as possible), correctly installing the sensors (orientation with respect to north, properly securing, and testing), distributing the sensors adequately in the region, and troubleshooting problems. One can also net points for efficient use of game play time. Setting up for game play in your local environment requires: (1) the Kinect hardware ( $145); (2) a computer with a Windows operating system (Mac users can use a Windows emulator); and (3) our free QCN game software (available from http://quakeinfo.ucsd.edu/ dkilb/WEB/QCN/Downloads.html).

TriPleX: a versatile dielectric photonic platform

NASA Astrophysics Data System (ADS)

Wörhoff, Kerstin; Heideman, René G.; Leinse, Arne; Hoekman, Marcel

2015-04-01

Photonic applications based on planar waveguide technology impose stringent requirements on properties such as optical propagation losses, light coupling to optical fibers, integration density, as well as on reliability and reproducibility. The latter is correlated to a high level of control of the refractive index and waveguide geometry. In this paper, we review a versatile dielectric waveguide platform, called TriPleX, which is based on alternating silicon nitride and silicon dioxide films. Fabrication with CMOS-compatible equipment based on low-pressure chemical vapor deposition enables the realization of stable material compositions being a prerequisite to the control of waveguide properties and modal shape. The transparency window of both materials allows for the realization of low-loss waveguides over a wide wavelength range (400 nm-2.35 μm). Propagation losses as low as 5×10-4 dB/cm are reported. Three basic geometries (box shell, double stripe, and filled box) can be distinguished. A specific tapering technology is developed for on-chip, low-loss (<0.1 dB) spotsize convertors, allowing for combining efficient fiber to chip coupling with high-contrast waveguides required for increased functional complexity as well as for hybrid integration with other photonic platforms such as InP and SOI. The functionality of the TriPleX platform is captured by verified basic building blocks. The corresponding library and associated design kit is available for multi-project wafer (MPW) runs. Several applications of this platform technology in communications, biomedicine, sensing, as well as a few special fields of photonics are treated in more detail.

Case for Deploying Complex Systems Utilizing Commodity Components

NASA Technical Reports Server (NTRS)

Bryant, Barry S.; Pitts, R. Lee

2003-01-01

When the International Space Station (ISS) finally reached an operational state, many of the Payload Operations and Integration Facility (POIF) hardware components were reaching end of life, COTS product costs were soaring, and the ISS budget was becoming severely constrained. However, most requirement development was complete. In addition, the ISS program is a fully functioning program with at least fifteen years of operational life remaining. Therefore it is critical that any upgrades, refurbishments, or enhancements be accomplished in realtime with minimal disruptions to service. For these and other reasons, it was necessary to ensure the viability of the POIF. Due to the to the breadth of capability of the POIF (a NASA ground station), it is believed that the lessons to be learned by other complex systems are applicable and any solutions garnered by the POIF are applicable to other complex systems as well. With that in mind, a number of new approaches have been investigated to increase the portability of the POIF and reduce the cost of refurbishment, operations, and maintenance. These new approaches were directed at the Total Cost of Ownership (TCO); not only the refurbishment but also current operational difficulties, licensing, and anticipation of the next refurbishment. Our basic premise is that technology had evolved dramatically since the concept of the POIF ground system and we should leverage our experience on this new technological landscape. Fortunately, Moore's law and market forces have changed the landscape considerably. These changes are manifest in five (5) ways that are particularly relevant to POIF: 1. Complex Instruction Set Computing (CISC) processors have advanced to unprecedented levels of compute capacity with a dramatic cost break, 2. Linux has become a major operating system supported by most vendors on a broad range of platforms, 3. Windows(TradeMark) based desktops are pervasive in the office environment, 4. Stable and affordable WindowsTM development environments and tools are available and offer a rich set of capabilities, 5. The WindowsTM 2000 provides a stable client platform, Therefore, five studies were proposed, developed, and are in the current process of deployment which dramatically reduces the cost of operations, maintenance, refurbishment, and deployment of a ground system. Restating and refining the basic premise stated earlier, it is possible to enhance operations through the replacement of hardware and software components with commodity based items wherever applicable. This will dramatically reduce the overall lifecycle cost of the project. The first study leveraged the POIF S secure, three-tier, web architecture to replace the client workstations with lower cost PC platforms. A second study initiated a review of COTS products to examine the level of added value of each product. This study included replacement of some COTS products with custom code, deletions, substitutions, and consolidation of COTS products. Studies three and four reviewed the server architectures of the data distribution systems and Enhanced HOSC System (EHS) command and telemetry system to propose migration to new platforms, both software and hardware. The final study reviewed current IP communication technologies, developed an operational model for flight operations, and demonstrated that voice over IP was practical and could be integrated into operations.

Residual motion compensation in ECG-gated interventional cardiac vasculature reconstruction

NASA Astrophysics Data System (ADS)

Schwemmer, C.; Rohkohl, C.; Lauritsch, G.; Müller, K.; Hornegger, J.

2013-06-01

Three-dimensional reconstruction of cardiac vasculature from angiographic C-arm CT (rotational angiography) data is a major challenge. Motion artefacts corrupt image quality, reducing usability for diagnosis and guidance. Many state-of-the-art approaches depend on retrospective ECG-gating of projection data for image reconstruction. A trade-off has to be made regarding the size of the ECG-gating window. A large temporal window is desirable to avoid undersampling. However, residual motion will occur in a large window, causing motion artefacts. We present an algorithm to correct for residual motion. Our approach is based on a deformable 2D-2D registration between the forward projection of an initial, ECG-gated reconstruction, and the original projection data. The approach is fully automatic and does not require any complex segmentation of vasculature, or landmarks. The estimated motion is compensated for during the backprojection step of a subsequent reconstruction. We evaluated the method using the publicly available CAVAREV platform and on six human clinical datasets. We found a better visibility of structure, reduced motion artefacts, and increased sharpness of the vessels in the compensated reconstructions compared to the initial reconstructions. At the time of writing, our algorithm outperforms the leading result of the CAVAREV ranking list. For the clinical datasets, we found an average reduction of motion artefacts by 13 ± 6%. Vessel sharpness was improved by 25 ± 12% on average.

Standards for efficient employment of wide-area motion imagery (WAMI) sensors

NASA Astrophysics Data System (ADS)

Randall, L. Scott; Maenner, Paul F.

2013-05-01

Airborne Wide Area Motion Imagery (WAMI) sensors provide the opportunity for continuous high-resolution surveillance of geographic areas covering tens of square kilometers. This is both a blessing and a curse. Data volumes from "gigapixel-class" WAMI sensors are orders of magnitude greater than for traditional "megapixel-class" video sensors. The amount of data greatly exceeds the capacities of downlinks to ground stations, and even if this were not true, the geographic coverage is too large for effective human monitoring. Although collected motion imagery is recorded on the platform, typically only small "windows" of the full field of view are transmitted to the ground; the full set of collected data can be retrieved from the recording device only after the mission has concluded. Thus, the WAMI environment presents several difficulties: (1) data is too massive for downlink; (2) human operator selection and control of the video windows may not be effective; (3) post-mission storage and dissemination may be limited by inefficient file formats; and (4) unique system implementation characteristics may thwart exploitation by available analysis tools. To address these issues, the National Geospatial-Intelligence Agency's Motion Imagery Standards Board (MISB) is developing relevant standard data exchange formats: (1) moving target indicator (MTI) and tracking metadata to support tipping and cueing of WAMI windows using "watch boxes" and "trip wires"; (2) control channel commands for positioning the windows within the full WAMI field of view; and (3) a full-field-of-view spatiotemporal tiled file format for efficient storage, retrieval, and dissemination. The authors previously provided an overview of this suite of standards. This paper describes the latest progress, with specific concentration on a detailed description of the spatiotemporal tiled file format.

Sci-Fri PM: Radiation Therapy, Planning, Imaging, and Special Techniques - 06: Patient-specific QA Procedure for Gated VMAT SABR Treatments using 10x Beam in Flattening-Filter Free Mode

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mestrovic, Ante; Chitsazzadeh, Shadi; Wells, Derek

2016-08-15

Purpose: To develop a highly sensitive patient specific QA procedure for gated VMAT stereotactic ablative radiotherapy (SABR) treatments. Methods: A platform was constructed to attach the translational stage of a Quasar respiratory motion phantom to a pinpoint ion chamber insert and move the ion chamber inside the ArcCheck. The Quasar phantom controller uses a patient-specific breathing pattern to translate the ion chamber in a superior-inferior direction inside the ArcCheck. With this system the ion chamber is used to QA the correct phase of the gated delivery and the ArcCheck diodes are used to QA the overall dose distribution. This novelmore » approach requires a single plan delivery for a complete QA of a gated plan. The sensitivity of the gating QA procedure was investigated with respect to the following parameters: PTV size, exhale duration, baseline drift, gating window size. Results: The difference between the measured dose to a point in the penumbra and the Eclipse calculated dose was under 2% for small residual motions. The QA procedure was independent of PTV size and duration of exhale. Baseline drift and gating window size, however, significantly affected the penumbral dose measurement, with differences of up to 30% compared to Eclipse. Conclusion: This study described a highly sensitive QA procedure for gated VMAT SABR treatments. The QA outcome was dependent on the gating window size and baseline drift. Analysis of additional patient breathing patterns is currently undergoing to determine a clinically relevant gating window size and an appropriate tolerance level for this procedure.« less

An add-in implementation of the RESAMPLING syntax under Microsoft EXCEL.

PubMed

Meineke, I

2000-10-01

The RESAMPLING syntax defines a set of powerful commands, which allow the programming of probabilistic statistical models with few, easily memorized statements. This paper presents an implementation of the RESAMPLING syntax using Microsoft EXCEL with Microsoft WINDOWS(R) as a platform. Two examples are given to demonstrate typical applications of RESAMPLING in biomedicine. Details of the implementation with special emphasis on the programming environment are discussed at length. The add-in is available electronically to interested readers upon request. The use of the add-in facilitates numerical statistical analyses of data from within EXCEL in a comfortable way.

LYMAN - The far ultraviolet explorer

NASA Technical Reports Server (NTRS)

Moos, Warren; Osantowski, John F.

1989-01-01

The LYMAN FUSE mission concept for far ultraviolet astronomy is presented. The wavelength window from 100 to 1200 A provides access to a wide range of important scientific problems in cosmology, galactic structure, stellar evolution, and planetary magnetospheres, which cannot be studied in any other way. The LYMAN FUSE Phase A study is examining in detail mission operations, instrumentation technology, the construction of the instrument module, and the interfaces between the Instrument Module and the Explorer Platform Mission. Most of the mission observing time will be allotted through a competitive Guest Observer program analogous to that in operation for the IUE.

Conference Proceedings of the America Institute for Aeronautics and Astronautics Missile Sciences Held in Monterey, California on 29 November - 1 December 1988. Volume 6. Navy Ballistic Missile Technology

DTIC Science & Technology

1988-11-01

atmospheric point the sensor line of sight to a target. Both oxidizers.) The stability of the booster plume as optical systems look out through windows...vertical. The optical layout olume unless it is tracking the UV plume outside for the UV camera is as shown in Figure 1. A the atmosphere. Thus, other...and olune and handoff to the missile in the atmosphere camera was used on the rear platform for the with high resolution optics . visible observation

Development and Implementation of GPS Correlator Structures in MATLAB and Simulink with Focus on SDR Applications: Implementation of a Standard GPS Correlator Architecture (Baseline) Implementation of the MIT Quicksynch Sparse Algorithm Development and Implementation of Parallel Circular Correlator Constructs

DTIC Science & Technology

2014-05-01

software is available for a wide variety of operating systems , including Unix, FreeBSD, Linux, Solaris, Novell NetWare, OS X, Microsoft Windows, OS/2, TPF...Word for Xenix systems . Subsequent versions were later written for several other platforms including IBM PCs running DOS (1983), Apple Macintosh ...this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204

The photokilling of bladder carcinoma cells in vitro by phenothiazine dyes.

PubMed

Fowler, G J; Rees, R C; Devonshire, R

1990-09-01

The potential photodynamic therapy photosensitizers Methylene Blue, Azure C, Methylene Violet, Thionine, Methylene Green, Haematoporphyrin, Nile Blue A, chloroaluminium phthalocyanine and bis-aluminium phthalocyanine were examined for their photoeffects and dark toxicity against a human superficial bladder carcinoma cell-line. By examination of [3H]thymidine uptake into dye-treated cells after irradiation with a copper-vapour pumped dye laser, it was found that Methylene Blue was the most phototoxic and dark toxic of all the dyes tested, suggesting that the dye might be of some use as a topically applied photodrug for use in photodynamic therapy of superficial or early-recurring carcinomas.

Construction of the energy matrix for complex atoms. Part VIII: Hyperfine structure HPC calculations for terbium atom

NASA Astrophysics Data System (ADS)

Elantkowska, Magdalena; Ruczkowski, Jarosław; Sikorski, Andrzej; Dembczyński, Jerzy

2017-11-01

A parametric analysis of the hyperfine structure (hfs) for the even parity configurations of atomic terbium (Tb I) is presented in this work. We introduce the complete set of 4fN-core states in our high-performance computing (HPC) calculations. For calculations of the huge hyperfine structure matrix, requiring approximately 5000 hours when run on a single CPU, we propose the methods utilizing a personal computer cluster or, alternatively a cluster of Microsoft Azure virtual machines (VM). These methods give a factor 12 performance boost, enabling the calculations to complete in an acceptable time.

R-Matrix Codes for Charged-Particle Induced Reactions in the Resolved Resonance Region (3), Summary Report of an IAEA Consultants' Meeting IAEA Headquarters, Vienna, Austria, 28-30 June 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leeb, Helmut; Dimitriou, Paraskevi; Thompson, Ian

A Consultants Meeting was held at the IAEA Headquarters, from 28 to 30 June 2017, to discuss the results of a test exercise that had been defined and assigned to all participants of the previous meeting held in December 2016. Five codes were used in this exercise: AMUR, AZURE2, RAC, SFRESCO and SAMMY. The results obtained from these codes were compared and further actions were proposed. Participants’ presentations and technical discussions, as well as proposed additional actions have been summarized in this report.

Xyce Parallel Electronic Simulator Users' Guide Version 6.7.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keiter, Eric R.; Aadithya, Karthik Venkatraman; Mei, Ting

This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been designed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: Capability to solve extremely large circuit problems by supporting large-scale parallel com- puting platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows one tomore » develop new types of analysis without requiring the implementation of analysis-specific device models. Device models that are specifically tailored to meet Sandia's needs, including some radiation- aware devices (for Sandia users only). Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase -- a message passing parallel implementation -- which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows. The information herein is subject to change without notice. Copyright c 2002-2017 Sandia Corporation. All rights reserved. Trademarks Xyce TM Electronic Simulator and Xyce TM are trademarks of Sandia Corporation. Orcad, Orcad Capture, PSpice and Probe are registered trademarks of Cadence Design Systems, Inc. Microsoft, Windows and Windows 7 are registered trademarks of Microsoft Corporation. Medici, DaVinci and Taurus are registered trademarks of Synopsys Corporation. Amtec and TecPlot are trademarks of Amtec Engineering, Inc. All other trademarks are property of their respective owners. Contacts World Wide Web http://xyce.sandia.gov https://info.sandia.gov/xyce (Sandia only) Email xyce@sandia.gov (outside Sandia) xyce-sandia@sandia.gov (Sandia only) Bug Reports (Sandia only) http://joseki-vm.sandia.gov/bugzilla http://morannon.sandia.gov/bugzilla« less

InfoTrac TFD: a microcomputer implementation of the Transcription Factor Database TFD with a graphical user interface.

PubMed

Hoeck, W G

1994-06-01

InfoTrac TFD provides a graphical user interface (GUI) for viewing and manipulating datasets in the Transcription Factor Database, TFD. The interface was developed in Filemaker Pro 2.0 by Claris Corporation, which provides cross platform compatibility between Apple Macintosh computers running System 7.0 and higher and IBM-compatibles running Microsoft Windows 3.0 and higher. TFD ASCII-tables were formatted to fit data into several custom data tables using Add/Strip, a shareware utility and Filemaker Pro's lookup feature. The lookup feature was also put to use to allow TFD data tables to become linked within a flat-file database management system. The 'Navigator', consisting of several pop-up menus listing transcription factor abbreviations, facilitates the search for transcription factor entries. Data are presented onscreen in several layouts, that can be further customized by the user. InfoTrac TFD makes the transcription factor database accessible to a much wider community of scientists by making it available on two popular microcomputer platforms.

owlcpp: a C++ library for working with OWL ontologies.

PubMed

Levin, Mikhail K; Cowell, Lindsay G

2015-01-01

The increasing use of ontologies highlights the need for a library for working with ontologies that is efficient, accessible from various programming languages, and compatible with common computational platforms. We developed owlcpp, a library for storing and searching RDF triples, parsing RDF/XML documents, converting triples into OWL axioms, and reasoning. The library is written in ISO-compliant C++ to facilitate efficiency, portability, and accessibility from other programming languages. Internally, owlcpp uses the Raptor RDF Syntax library for parsing RDF/XML and the FaCT++ library for reasoning. The current version of owlcpp is supported under Linux, OSX, and Windows platforms and provides an API for Python. The results of our evaluation show that, compared to other commonly used libraries, owlcpp is significantly more efficient in terms of memory usage and searching RDF triple stores. owlcpp performs strict parsing and detects errors ignored by other libraries, thus reducing the possibility of incorrect semantic interpretation of ontologies. owlcpp is available at http://owl-cpp.sf.net/ under the Boost Software License, Version 1.0.

Biomechanical ToolKit: Open-source framework to visualize and process biomechanical data.

PubMed

Barre, Arnaud; Armand, Stéphane

2014-04-01

C3D file format is widely used in the biomechanical field by companies and laboratories to store motion capture systems data. However, few software packages can visualize and modify the integrality of the data in the C3D file. Our objective was to develop an open-source and multi-platform framework to read, write, modify and visualize data from any motion analysis systems using standard (C3D) and proprietary file formats (used by many companies producing motion capture systems). The Biomechanical ToolKit (BTK) was developed to provide cost-effective and efficient tools for the biomechanical community to easily deal with motion analysis data. A large panel of operations is available to read, modify and process data through C++ API, bindings for high-level languages (Matlab, Octave, and Python), and standalone application (Mokka). All these tools are open-source and cross-platform and run on all major operating systems (Windows, Linux, MacOS X). Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Operation and control software for APNEA

DOE Office of Scientific and Technical Information (OSTI.GOV)

McClelland, J.H.; Storm, B.H. Jr.; Ahearn, J.

1997-11-01

The human interface software for the Lockheed Martin Specialty Components (LMSC) Active/Passive Neutron Examination & Analysis System (APENA) provides a user friendly operating environment for the movement and analysis of waste drums. It is written in Microsoft Visual C++ on a Windows NT platform. Object oriented and multitasking techniques are used extensively to maximize the capability of the system. A waste drum is placed on a loading platform with a fork lift and then automatically moved into the APNEA chamber in preparation for analysis. A series of measurements is performed, controlled by menu commands to hardware components attached as peripheralmore » devices, in order to create data files for analysis. The analysis routines use the files to identify the pertinent radioactive characteristics of the drum, including the type, location, and quantity of fissionable material. At the completion of the measurement process, the drum is automatically unloaded and the data are archived in preparation for storage as part of the drum`s data signature. 3 figs.« less

Multiparametric, Longitudinal Optical Coherence Tomography Imaging Reveals Acute Injury and Chronic Recovery in Experimental Ischemic Stroke

PubMed Central

Srinivasan, Vivek J.; Mandeville, Emiri T.; Can, Anil; Blasi, Francesco; Climov, Mihail; Daneshmand, Ali; Lee, Jeong Hyun; Yu, Esther; Radhakrishnan, Harsha; Lo, Eng H.; Sakadžić, Sava; Eikermann-Haerter, Katharina; Ayata, Cenk

2013-01-01

Progress in experimental stroke and translational medicine could be accelerated by high-resolution in vivo imaging of disease progression in the mouse cortex. Here, we introduce optical microscopic methods that monitor brain injury progression using intrinsic optical scattering properties of cortical tissue. A multi-parametric Optical Coherence Tomography (OCT) platform for longitudinal imaging of ischemic stroke in mice, through thinned-skull, reinforced cranial window surgical preparations, is described. In the acute stages, the spatiotemporal interplay between hemodynamics and cell viability, a key determinant of pathogenesis, was imaged. In acute stroke, microscopic biomarkers for eventual infarction, including capillary non-perfusion, cerebral blood flow deficiency, altered cellular scattering, and impaired autoregulation of cerebral blood flow, were quantified and correlated with histology. Additionally, longitudinal microscopy revealed remodeling and flow recovery after one week of chronic stroke. Intrinsic scattering properties serve as reporters of acute cellular and vascular injury and recovery in experimental stroke. Multi-parametric OCT represents a robust in vivo imaging platform to comprehensively investigate these properties. PMID:23940761

Label-Free Detection of Cardiac Troponin-I Using Carbon Nanofiber Based Nanoelectrode Arrays

NASA Technical Reports Server (NTRS)

Periyakaruppan, Adaikkappan; Koehne, Jessica Erin; Gandhiraman, Ram P.; Meyyappan, M.

2013-01-01

A sensor platform based on vertically aligned carbon nanofibers (CNFs) has been developed. Their inherent nanometer scale, high conductivity, wide potential window, good biocompatibility and well-defined surface chemistry make them ideal candidates as biosensor electrodes. A carbon nanofiber (CNF) multiplexed array has been fabricated with 9 sensing pads, each containing 40,000 carbon nanofibers as nanoelectrodes. Here, we report the use of vertically aligned CNF nanoelectrodes for the detection of cardiac Troponin-I for the early diagnosis of myocardial infarction. Antibody, antitroponin, probe immobilization and subsequent binding to human cardiac troponin-I were characterized using electrochemical impedance spectroscopy and cyclic voltammetry techniques. Each step of the modification process resulted in changes in electrical capacitance or resistance to charge transfer due to the changes at the electrode surface upon antibody immobilization and binding to the specific antigen. This sensor demonstrates high sensitivity, down to 0.2 ng/mL, and good selectivity making this platform a good candidate for early stage diagnosis of myocardial infarction.

A new e-learning platform for radiology education (RadEd).

PubMed

Xiberta, Pau; Boada, Imma

2016-04-01

One of the key elements of e-learning platforms is the content provided to the students. Content creation is a time demanding task that requires teachers to prepare material taking into account that it will be accessed on-line. Moreover, the teacher is restricted by the functionalities provided by the e-learning platforms. In contexts such as radiology where images have a key role, the required functionalities are still more specific and difficult to be provided by these platforms. Our purpose is to create a framework to make teacher's tasks easier, specially when he has to deal with contents where images have a main role. In this paper, we present RadEd, a new web-based teaching framework that integrates a smart editor to create case-based exercises that support image interaction such as changing the window width and the grey scale used to render the image, taking measurements on the image, attaching labels to images and selecting parts of the images, amongst others. It also provides functionalities to prepare courses with different topics, exercises and theory material, and also functionalities to control students' work. Different experts have used RadEd and all of them have considered it a very useful and valuable tool to prepare courses where radiological images are the main component. RadEd provides teachers functionalities to prepare more realistic cases and students the ability to make a more specific diagnosis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Scalable Fabrication of Integrated Nanophotonic Circuits on Arrays of Thin Single Crystal Diamond Membrane Windows.

PubMed

Piracha, Afaq H; Rath, Patrik; Ganesan, Kumaravelu; Kühn, Stefan; Pernice, Wolfram H P; Prawer, Steven

2016-05-11

Diamond has emerged as a promising platform for nanophotonic, optical, and quantum technologies. High-quality, single crystalline substrates of acceptable size are a prerequisite to meet the demanding requirements on low-level impurities and low absorption loss when targeting large photonic circuits. Here, we describe a scalable fabrication method for single crystal diamond membrane windows that achieves three major goals with one fabrication method: providing high quality diamond, as confirmed by Raman spectroscopy; achieving homogeneously thin membranes, enabled by ion implantation; and providing compatibility with established planar fabrication via lithography and vertical etching. On such suspended diamond membranes we demonstrate a suite of photonic components as building blocks for nanophotonic circuits. Monolithic grating couplers are used to efficiently couple light between photonic circuits and optical fibers. In waveguide coupled optical ring resonators, we find loaded quality factors up to 66 000 at a wavelength of 1560 nm, corresponding to propagation loss below 7.2 dB/cm. Our approach holds promise for the scalable implementation of future diamond quantum photonic technologies and all-diamond photonic metrology tools.

S-Genius, a universal software platform with versatile inverse problem resolution for scatterometry

NASA Astrophysics Data System (ADS)

Fuard, David; Troscompt, Nicolas; El Kalyoubi, Ismael; Soulan, Sébastien; Besacier, Maxime

2013-05-01

S-Genius is a new universal scatterometry platform, which gathers all the LTM-CNRS know-how regarding the rigorous electromagnetic computation and several inverse problem solver solutions. This software platform is built to be a userfriendly, light, swift, accurate, user-oriented scatterometry tool, compatible with any ellipsometric measurements to fit and any types of pattern. It aims to combine a set of inverse problem solver capabilities — via adapted Levenberg- Marquard optimization, Kriging, Neural Network solutions — that greatly improve the reliability and the velocity of the solution determination. Furthermore, as the model solution is mainly vulnerable to materials optical properties, S-Genius may be coupled with an innovative material refractive indices determination. This paper will a little bit more focuses on the modified Levenberg-Marquardt optimization, one of the indirect method solver built up in parallel with the total SGenius software coding by yours truly. This modified Levenberg-Marquardt optimization corresponds to a Newton algorithm with an adapted damping parameter regarding the definition domains of the optimized parameters. Currently, S-Genius is technically ready for scientific collaboration, python-powered, multi-platform (windows/linux/macOS), multi-core, ready for 2D- (infinite features along the direction perpendicular to the incident plane), conical, and 3D-features computation, compatible with all kinds of input data from any possible ellipsometers (angle or wavelength resolved) or reflectometers, and widely used in our laboratory for resist trimming studies, etching features characterization (such as complex stack) or nano-imprint lithography measurements for instance. The work about kriging solver, neural network solver and material refractive indices determination is done (or about to) by other LTM members and about to be integrated on S-Genius platform.

MPPhys—A many-particle simulation package for computational physics education

NASA Astrophysics Data System (ADS)

Müller, Thomas

2014-03-01

In a first course to classical mechanics elementary physical processes like elastic two-body collisions, the mass-spring model, or the gravitational two-body problem are discussed in detail. The continuation to many-body systems, however, is deferred to graduate courses although the underlying equations of motion are essentially the same and although there is a strong motivation for high-school students in particular because of the use of particle systems in computer games. The missing link between the simple and the more complex problem is a basic introduction to solve the equations of motion numerically which could be illustrated, however, by means of the Euler method. The many-particle physics simulation package MPPhys offers a platform to experiment with simple particle simulations. The aim is to give a principle idea how to implement many-particle simulations and how simulation and visualization can be combined for interactive visual explorations. Catalogue identifier: AERR_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AERR_v1_0.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 111327 No. of bytes in distributed program, including test data, etc.: 608411 Distribution format: tar.gz Programming language: C++, OpenGL, GLSL, OpenCL. Computer: Linux and Windows platforms with OpenGL support. Operating system: Linux and Windows. RAM: Source Code 4.5 MB Complete package 242 MB Classification: 14, 16.9. External routines: OpenGL, OpenCL Nature of problem: Integrate N-body simulations, mass-spring models Solution method: Numerical integration of N-body-simulations, 3D-Rendering via OpenGL. Running time: Problem dependent

Validation of the Mass-Extraction-Window for Quantitative Methods Using Liquid Chromatography High Resolution Mass Spectrometry.

PubMed

Glauser, Gaétan; Grund, Baptiste; Gassner, Anne-Laure; Menin, Laure; Henry, Hugues; Bromirski, Maciej; Schütz, Frédéric; McMullen, Justin; Rochat, Bertrand

2016-03-15

A paradigm shift is underway in the field of quantitative liquid chromatography-mass spectrometry (LC-MS) analysis thanks to the arrival of recent high-resolution mass spectrometers (HRMS). The capability of HRMS to perform sensitive and reliable quantifications of a large variety of analytes in HR-full scan mode is showing that it is now realistic to perform quantitative and qualitative analysis with the same instrument. Moreover, HR-full scan acquisition offers a global view of sample extracts and allows retrospective investigations as virtually all ionized compounds are detected with a high sensitivity. In time, the versatility of HRMS together with the increasing need for relative quantification of hundreds of endogenous metabolites should promote a shift from triple-quadrupole MS to HRMS. However, a current "pitfall" in quantitative LC-HRMS analysis is the lack of HRMS-specific guidance for validated quantitative analyses. Indeed, false positive and false negative HRMS detections are rare, albeit possible, if inadequate parameters are used. Here, we investigated two key parameters for the validation of LC-HRMS quantitative analyses: the mass accuracy (MA) and the mass-extraction-window (MEW) that is used to construct the extracted-ion-chromatograms. We propose MA-parameters, graphs, and equations to calculate rational MEW width for the validation of quantitative LC-HRMS methods. MA measurements were performed on four different LC-HRMS platforms. Experimentally determined MEW values ranged between 5.6 and 16.5 ppm and depended on the HRMS platform, its working environment, the calibration procedure, and the analyte considered. The proposed procedure provides a fit-for-purpose MEW determination and prevents false detections.

Gold-modified indium tin oxide as a transparent window in optoelectronic diagnostics of electrochemically active biofilms.

PubMed

Schmidt, Igor; Gad, Alaaeldin; Scholz, Gregor; Boht, Heidi; Martens, Michael; Schilling, Meinhard; Suryo Wasisto, Hutomo; Waag, Andreas; Schröder, Uwe

2017-08-15

Microbial electrochemical technologies (METs) are one of the emerging green bioenergy domains that are utilizing microorganisms for wastewater treatment or electrosynthesis. Real-time monitoring of bioprocess during operation is a prerequisite for understanding and further improving bioenergy harvesting. Optical methods are powerful tools for this, but require transparent, highly conductive and biocompatible electrodes. Whereas indium tin oxide (ITO) is a well-known transparent conductive oxide, it is a non-ideal platform for biofilm growth. Here, a straightforward approach of surface modification of ITO anodes with gold (Au) is demonstrated, to enhance direct microbial biofilm cultivation on their surface and to improve the produced current densities. The trade-off between the electrode transmittance (critical for the underlying integrated sensors) and the enhanced growth of biofilms (crucial for direct monitoring) is studied. Au-modified ITO electrodes show a faster and reproducible biofilm growth with three times higher maximum current densities and about 6.9 times thicker biofilms compared to their unmodified ITO counterparts. The electrochemical analysis confirms the enhanced performance and the reversibility of the ITO/Au electrodes. The catalytic effect of Au on the ITO surface seems to be the key factor of the observed performance improvement since the changes in the electrode conductivity and their surface wettability are relatively small and in the range of ITO. An integrated platform for the ITO/Au transparent electrode with light-emitting diodes was fabricated and its feasibility for optical biofilm thickness monitoring is demonstrated. Such transparent electrodes with embedded catalytic metals can serve as multifunctional windows for biofilm diagnostic microchips. Copyright © 2017 Elsevier B.V. All rights reserved.

UltraPse: A Universal and Extensible Software Platform for Representing Biological Sequences.

PubMed

Du, Pu-Feng; Zhao, Wei; Miao, Yang-Yang; Wei, Le-Yi; Wang, Likun

2017-11-14

With the avalanche of biological sequences in public databases, one of the most challenging problems in computational biology is to predict their biological functions and cellular attributes. Most of the existing prediction algorithms can only handle fixed-length numerical vectors. Therefore, it is important to be able to represent biological sequences with various lengths using fixed-length numerical vectors. Although several algorithms, as well as software implementations, have been developed to address this problem, these existing programs can only provide a fixed number of representation modes. Every time a new sequence representation mode is developed, a new program will be needed. In this paper, we propose the UltraPse as a universal software platform for this problem. The function of the UltraPse is not only to generate various existing sequence representation modes, but also to simplify all future programming works in developing novel representation modes. The extensibility of UltraPse is particularly enhanced. It allows the users to define their own representation mode, their own physicochemical properties, or even their own types of biological sequences. Moreover, UltraPse is also the fastest software of its kind. The source code package, as well as the executables for both Linux and Windows platforms, can be downloaded from the GitHub repository.

The RHYTMME system: an operational real-time warning and mapping system for flash floods, debris flows, landslide and rock falls in Southeastern France.

NASA Astrophysics Data System (ADS)

Fouchier, Catherine; Mériaux, Patrice; Atger, Frédéric; Ecrepont, Stéphane; Liébault, Frédéric; Bertrand, Mélanie; Bel, Coraline; Batista, Dominique; Azemard, Pierre; Saint-Martin, Clotilde; Javelle, Pierre

2016-04-01

Almost all municipalities of Southeastern France are concerned by natural hazards triggered by heavy rainfalls such as floods, debris flows, landslides and rock falls. Although some tools exist to forecast and monitor heavy rains and floods in France, their spatial resolution sometimes does not meet the needs of local risk managers who have to monitor events at a small spatial scale. In order to improve the risk management in the mountainous and Mediterranean areas of Southeastern France, Irstea and Météo-France have led the RHYTMME project. The goal of this project is to improve the ability to forecast and localize high-risk rainfall-induced hazards in the Provence-Alpes-Côte d'Azur administrative area. This goal is currently under achievement thanks to the implementation of a real-time warning and mapping system for rainfall induced natural hazards, fed by radar data and whose outputs are made available via the Internet to operators in charge of risk management (local and regional authorities, emergency and rescue services, road and rail networks managers, ...). This system provides maps which display in real-time: - the radar estimations of rainfall for different rain durations and at the spatial resolution of 1 km² (Westrelin et al., 2013), - the estimation of the scarcity of these rainfall estimations, also at the spatial resolution of 1 km², thanks to a comparison with threshold values provided by a regionalized stochastic hourly point rainfall generator (Arnaud et al., 2007), - an anticipation of the rivers discharges, computed at the outlet of 1700 watersheds of Southeastern France thanks to the AIGA warning system which combines a rainfall runoff model and an estimation of the scarcity of the discharges thanks to a comparison with threshold values (Javelle et al., 2014). Maps of susceptibility to debris flow, landslide and rock falls can also be displayed in the RHYTMME warning system along with the real time maps of rainfall hazard (Batista, 2013a, 2013b; Bertrand, 2014). It enables to identify, during intense events, the reaches the more likely to generate and/or to spread debris flow and the areas the more likely to generate landslide and/or rock falls. The RHYTMME warning and mapping system is now fully operational. It is currently being provided to local authorities (City councils, River boards, …) as well as State authorities in charge of risk managements in the Provence-Alpes-Côte d'Azur administrative area. Training sessions are organized in order to help these end-users to handle the system. References Arnaud P., Fine J.-A. and Lavabre J. (2007). An hourly rainfall generation model applicable to all types of climate. Atmospheric Research 85(2): 230-242. Batista D., Azémard P., Boutry M. (2013). Prévision de l'aléa glissement de terrain et analyse statistique des facteurs de prédisposition par l'outil SIG, sur la région Provence-Alpes-Côte d'Azur. Journées Aléas Gravitaires, 17 et 18/9/2013 - Grenoble, 11 p. Batista D., Azémard P., Rougé A.C., Dumalin M., Rault C. (2013). Prévision de l'aléa chute de blocs, analyse statistique des facteurs de prédisposition et des critères de déclenchement sur la région Provence-Alpes-Côte d'Azur. Journées Aléas Gravitaires, 17 et 18/9/2013 - Grenoble, 11 p. Bertrand M. (2014). Approches régionales de la susceptibilité torrentielle dans les Alpes du Sud. Thèse de Doctorat, École Normale Supérieure de Lyon, 162 pp. Javelle P., Demargne J., Defrance D., Pansu J., Arnaud P. (2014). Evaluating flash-flood warnings at ungauged locations using post-event surveys: A case study with the AIGA warning system. Hydrological Sciences Journal 59 (7): 1390-1402. Westrelin S., Mériaux P., Dalle S., Fradon B., Jamet G. (2013). Déploiement d'un réseau de radars pour anticiper les risques hydro-météorologiques, La Météorologie 8 (83): 69-79.

Sedimentary record of the obduction of the Samail ophiolite in northern Oman: the Muti Formation in the Sail Hatat window

NASA Astrophysics Data System (ADS)

Ducassou, Céline; Robin, Cecile; Poujol, Marc; Al-Rahbi, Basim; Estournes, Guilhem

2016-04-01

The obduction of the Samail Ophiolite in Oman took place during the Upper Cretaceous. Since then, the northern part of Oman has been relatively preserved from deformation and is therefore one of the best places to study obduction processes. In addition, radiometric data provide good constraints on the timing of obduction from the formation of the metamorphic sole until the exhumation of the high-pressure / low-temperature metamorphic rocks involved in the subduction zone below the oceanic lithosphere. However, the response of the continental margin during the obduction is still poorly constrained. If most of the models suggest the development of a flexural basin and an associated forebulge such as in continental collision, their recognition within the syn-tectonic deposits led to different interpretations. The geometry of the youngest syn-tectonic deposits (Fiqa Formation) is relatively well constrained by sub-surface data that suggest a southward migration of the depocenter and progressive onlaps on the southern margin of the basin. The context of sedimentation of the oldest syn-tectonic deposits (Muti Formation) preserved below the nappes in the Oman Mountains is, however, still poorly understood. The location of the sedimentation area with respect of the forebulge, for instance, remains unclear. In order to acquire better constraints on the record, on the Arabian platform, of first steps of the obduction, the analysis of several sections of the Muti Formation has been performed. We present here our main results for the north-eastern part of the Oman Mountains, in the Sail Hatat window, where the thickest successions have been described in Quryat and Bidbid area, respectively located in the eastern and western part of the Sail Hatat window. Sedimentological and structural analysis have been combined to reconstitute the evolution of depositional environments in areas strongly affected by deformation. In addition, systematic measurements and restoration of palaeocurrents, petrological determinations and geochronological analyses (LA-ICPMS) on detrital zircons have been performed in order to identify the source areas. In both studied areas, the sedimentary series are characterised by mainly carbonated slope to basin deposits. The more distal deposits identified are in the easternmost part (Quryat area). Episodes of terrigenous input are recorded in both areas and palaeocurrents indicate a source area located toward the south, in agreement with the dating obtained on detrital zircons, yielding a dominant population at ca. 800 Ma. These results suggest that the Proterozoic basement was being eroded during the sedimentation of the Muti Formation in the Sail Hatat window and an episode of uplift of the Huqf High is therefore inferred. These results allow to discuss the evolution of the north-easternmost part of the Arabian platform during the first steps of the obduction.

Modular packaging concept for MEMS and MOEMS

NASA Astrophysics Data System (ADS)

Stenchly, Vanessa; Reinert, Wolfgang; Quenzer, Hans-Joachim

2017-11-01

Wherever technical systems detect objects in their environment or interact with people, optical devices may play an important role. Light can be relatively easily produced and spatially and temporally modulated. Laser can project sharp images over long distances or cut materials in short distances. Depending on the wavelength an invisible scanning in near infrared for gesture recognition is possible as well as a projection of brilliant colour images. For several years, the Fraunhofer ISIT develops Opto-Packaging processes based on the viscous reshaping of glass wafers: First, hermetically sealed laser micro-mirror scanners WLP with inclined windows deflect in the central light reflex of the window out of the image area. Second, housing with lateral light exit permits hermetic sealing of edge-emitting lasers for highest reliability and durability. Such systems are currently experiencing an extremely high interest of the industry in all segments, from consumer to automotive through to materials processing. Our modular Opto-Packaging platform enables fast product developments. Housing for opto mechanical MEMS devices are equipped with inclined windows to minimize distortion, stray light and reflection losses. The hot viscous glass forming technology is also applied to functionalized substrate wafers which possess areas with high heat dissipation in addition to thermally insulating areas. Electrical contacts may be realized with metal filled vias or TGV (Through Glass Vias). The modular system reduces the development times for new, miniaturized optical systems so that manufacturers can focus on the essentials in their development, namely their product functionalities.

Comparing the Microsoft Kinect to a traditional mouse for adjusting the viewed tissue densities of three-dimensional anatomical structures

NASA Astrophysics Data System (ADS)

Juhnke, Bethany; Berron, Monica; Philip, Adriana; Williams, Jordan; Holub, Joseph; Winer, Eliot

2013-03-01

Advancements in medical image visualization in recent years have enabled three-dimensional (3D) medical images to be volume-rendered from magnetic resonance imaging (MRI) and computed tomography (CT) scans. Medical data is crucial for patient diagnosis and medical education, and analyzing these three-dimensional models rather than two-dimensional (2D) slices would enable more efficient analysis by surgeons and physicians, especially non-radiologists. An interaction device that is intuitive, robust, and easily learned is necessary to integrate 3D modeling software into the medical community. The keyboard and mouse configuration does not readily manipulate 3D models because these traditional interface devices function within two degrees of freedom, not the six degrees of freedom presented in three dimensions. Using a familiar, commercial-off-the-shelf (COTS) device for interaction would minimize training time and enable maximum usability with 3D medical images. Multiple techniques are available to manipulate 3D medical images and provide doctors more innovative ways of visualizing patient data. One such example is windowing. Windowing is used to adjust the viewed tissue density of digital medical data. A software platform available at the Virtual Reality Applications Center (VRAC), named Isis, was used to visualize and interact with the 3D representations of medical data. In this paper, we present the methodology and results of a user study that examined the usability of windowing 3D medical imaging using a Kinect™ device compared to a traditional mouse.

Temporally rendered automatic cloud extraction (TRACE) system

NASA Astrophysics Data System (ADS)

Bodrero, Dennis M.; Yale, James G.; Davis, Roger E.; Rollins, John M.

1999-10-01

Smoke/obscurant testing requires that 2D cloud extent be extracted from visible and thermal imagery. These data are used alone or in combination with 2D data from other aspects to make 3D calculations of cloud properties, including dimensions, volume, centroid, travel, and uniformity. Determining cloud extent from imagery has historically been a time-consuming manual process. To reduce time and cost associated with smoke/obscurant data processing, automated methods to extract cloud extent from imagery were investigated. The TRACE system described in this paper was developed and implemented at U.S. Army Dugway Proving Ground, UT by the Science and Technology Corporation--Acuity Imaging Incorporated team with Small Business Innovation Research funding. TRACE uses dynamic background subtraction and 3D fast Fourier transform as primary methods to discriminate the smoke/obscurant cloud from the background. TRACE has been designed to run on a PC-based platform using Windows. The PC-Windows environment was chosen for portability, to give TRACE the maximum flexibility in terms of its interaction with peripheral hardware devices such as video capture boards, removable media drives, network cards, and digital video interfaces. Video for Windows provides all of the necessary tools for the development of the video capture utility in TRACE and allows for interchangeability of video capture boards without any software changes. TRACE is designed to take advantage of future upgrades in all aspects of its component hardware. A comparison of cloud extent determined by TRACE with manual method is included in this paper.

CERN alerter—RSS based system for information broadcast to all CERN offices

NASA Astrophysics Data System (ADS)

Otto, R.

2008-07-01

Nearly every large organization uses a tool to broadcast messages and information across the internal campus (messages like alerts announcing interruption in services or just information about upcoming events). These tools typically allow administrators (operators) to send 'targeted' messages which are sent only to specific groups of users or computers, e/g only those located in a specified building or connected to a particular computing service. CERN has a long history of such tools: CERNVMS's SPM_quotMESSAGE command, Zephyr [2] and the most recent the NICE Alerter based on the NNTP protocol. The NICE Alerter used on all Windows-based computers had to be phased out as a consequence of phasing out NNTP at CERN. The new solution to broadcast information messages on the CERN campus continues to provide the service based on cross-platform technologies, hence minimizing custom developments and relying on commercial software as much as possible. The new system, called CERN Alerter, is based on RSS (Really Simple Syndication) [9] for the transport protocol and uses Microsoft SharePoint as the backend for database and posting interface. The windows-based client relies on Internet Explorer 7.0 with custom code to trigger the window pop-ups and the notifications for new events. Linux and Mac OS X clients could also rely on any RSS readers to subscribe to targeted notifications. The paper covers the architecture and implementation aspects of the new system.

Laser Ranging for Effective and Accurate Tracking of Space Debris in Low Earth Orbits

NASA Astrophysics Data System (ADS)

Blanchet, Guillaume; Haag, Herve; Hennegrave, Laurent; Assemat, Francois; Vial, Sophie; Samain, Etienne

2013-08-01

The paper presents the results of preliminary design options for an operational laser ranging system adapted to the measurement of the distance of space debris. Thorough analysis of the operational parameters is provided with identification of performance drivers and assessment of enabling design options. Results from performance simulation demonstrate how the range measurement enables improvement of the orbit determination when combined with astrometry. Besides, experimental results on rocket-stage class debris in LEO were obtained by Astrium beginning of 2012, in collaboration with the Observatoire de la Côte d'Azur (OCA), by operating an experimental laser ranging system supported by the MéO (Métrologie Optique) telescope.

[Breast cancer screening programme: a media campaign for isolated or marginalised women].

PubMed

Mansour, Z; Fleur, L; Saugeron, A M; Merle, N; Marquis, D; Lucas, C

2005-12-01

The six counties in the Provence-Alpes-Cote d'Azur region are all well-equipped to offer widespread breast cancer screening programmes. The regional technical committee for breast cancer screening has entrusted the regional health education committee (CRES) with the task of organsing an incentive campaign targeted at reaching disenfranchised or isolated women. With the collaboration of all its partners, the CRES proposed three examples of interventions: training sessions for a variety of health care professionals, publishing communication tools, and creating partnerships with the press. Financed by the state, this campaign essentially relies upon partnership mobilisation, social solidarity, interpersonal communication and the most popular and easily accessible information channels among this population group.

Cloud-based robot remote control system for smart factory

NASA Astrophysics Data System (ADS)

Wu, Zhiming; Li, Lianzhong; Xu, Yang; Zhai, Jingmei

2015-12-01

With the development of internet technologies and the wide application of robots, there is a prospect (trend/tendency) of integration between network and robots. A cloud-based robot remote control system over networks for smart factory is proposed, which enables remote users to control robots and then realize intelligent production. To achieve it, a three-layer system architecture is designed including user layer, service layer and physical layer. Remote control applications running on the cloud server is developed on Microsoft Azure. Moreover, DIV+ CSS technologies are used to design human-machine interface to lower maintenance cost and improve development efficiency. Finally, an experiment is implemented to verify the feasibility of the program.

BioVEC: a program for biomolecule visualization with ellipsoidal coarse-graining.

PubMed

Abrahamsson, Erik; Plotkin, Steven S

2009-09-01

Biomolecule Visualization with Ellipsoidal Coarse-graining (BioVEC) is a tool for visualizing molecular dynamics simulation data while allowing coarse-grained residues to be rendered as ellipsoids. BioVEC reads in configuration files, which may be output from molecular dynamics simulations that include orientation output in either quaternion or ANISOU format, and can render frames of the trajectory in several common image formats for subsequent concatenation into a movie file. The BioVEC program is written in C++, uses the OpenGL API for rendering, and is open source. It is lightweight, allows for user-defined settings for and texture, and runs on either Windows or Linux platforms.

Key Technologies of Phone Storage Forensics Based on ARM Architecture

NASA Astrophysics Data System (ADS)

Zhang, Jianghan; Che, Shengbing

2018-03-01

Smart phones are mainly running Android, IOS and Windows Phone three mobile platform operating systems. The android smart phone has the best market shares and its processor chips are almost ARM software architecture. The chips memory address mapping mechanism of ARM software architecture is different with x86 software architecture. To forensics to android mart phone, we need to understand three key technologies: memory data acquisition, the conversion mechanism from virtual address to the physical address, and find the system’s key data. This article presents a viable solution which does not rely on the operating system API for a complete solution to these three issues.

LK Scripting Language

DOE Office of Scientific and Technical Information (OSTI.GOV)

The LK scripting language is a simple and fast computer programming language designed for easy integration with existing software to enable automation of tasks. The LK language is used by NREL’s System Advisor Model (SAM), the SAM Software Development Kit (SDK), and SolTrace products. LK is easy extensible and adaptable to new software due to its small footprint and is designed to be statically linked into other software. It is written in standard C++, is cross-platform (Windows, Linux, and OSX), and includes optional portions that enable direct integration with graphical user interfaces written in the open source C++ wxWidgets Versionmore » 3.0+ toolkit.« less

The personal receiving document management and the realization of email function in OAS

NASA Astrophysics Data System (ADS)

Li, Biqing; Li, Zhao

2017-05-01

This software is an independent software system, suitable for small and medium enterprises, contains personal office, scientific research project management and system management functions, independently run in relevant environment, and to solve practical needs. This software is an independent software system, using the current popular B/S (browser/server) structure and ASP.NET technology development, using the Windows 7 operating system, Microsoft SQL Server2005 Visual2008 and database as a development platform, suitable for small and medium enterprises, contains personal office, scientific research project management and system management functions, independently run in relevant environment, and to solve practical needs.

A browse facility for Earth science remote sensing data: Center director's discretionary fund final report

NASA Technical Reports Server (NTRS)

Meyer, P. J.

1993-01-01

An image data visual browse facility is developed for a UNIX platform using the X Windows 11 system. It allows one to visually examine reduced resolution image data to determine which data are applicable for further research. Links with a relational data base manager then allow one to extract not only the full resolution image data, but any other ancillary data related to the case study. Various techniques are examined for compression of the image data in order to reduce data storage requirements and time necessary to transmit the data on the internet. Data used were from the WetNet project.

Layered virus protection for the operations and administrative messaging system

NASA Technical Reports Server (NTRS)

Cortez, R. H.

2002-01-01

NASA's Deep Space Network (DSN) is critical in supporting the wide variety of operating and plannedunmanned flight projects. For day-to-day operations it relies on email communication between the three Deep Space Communication Complexes (Canberra, Goldstone, Madrid) and NASA's Jet Propulsion Laboratory. The Operations & Administrative Messaging system, based on the Microsoft Windows NTand Exchange platform, provides the infrastructure that is required for reliable, mission-critical messaging. The reliability of this system, however, is threatened by the proliferation of email viruses that continue to spread at alarming rates. A layered approach to email security has been implemented across the DSN to protect against this threat.

ImagePy: an open-source, Python-based and platform-independent software package for boimage analysis.

PubMed

Wang, Anliang; Yan, Xiaolong; Wei, Zhijun

2018-04-27

This note presents the design of a scalable software package named ImagePy for analysing biological images. Our contribution is concentrated on facilitating extensibility and interoperability of the software through decoupling the data model from the user interface. Especially with assistance from the Python ecosystem, this software framework makes modern computer algorithms easier to be applied in bioimage analysis. ImagePy is free and open source software, with documentation and code available at https://github.com/Image-Py/imagepy under the BSD license. It has been tested on the Windows, Mac and Linux operating systems. wzjdlut@dlut.edu.cn or yxdragon@imagepy.org.

KSC-05PD-1077

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. At Launch Complex 39B, technicians construct a platform in Space Shuttle Discovery's payload bay to support an upcoming borescope inspection of the retract link assembly on the orbiter's main landing gear door. The inspection is a precautionary measure after a small crack was found in a retract link assembly on the right-hand main landing gear on orbiter Atlantis. An initial review of the closeout photos of the link assembly on Discovery did not reveal any cracks. Discovery is scheduled to return the Space Shuttle fleet to operational status on mission STS-114. This additional work does not impact the launch planning window of July 13-31.

KSC-05PD-1080

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. At Launch Complex 39B, technicians construct a platform in Space Shuttle Discovery's payload bay to support an upcoming borescope inspection of the retract link assembly on the orbiter's main landing gear door. The inspection is a precautionary measure after a small crack was found in a retract link assembly on the right-hand main landing gear on orbiter Atlantis. An initial review of the closeout photos of the link assembly on Discovery did not reveal any cracks. Discovery is scheduled to return the Space Shuttle fleet to operational status on mission STS-114. This additional work does not impact the launch planning window of July 13-31.

KSC-05PD-1079

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. At Launch Complex 39B, technicians construct a platform in Space Shuttle Discovery's payload bay to support an upcoming borescope inspection of the retract link assembly on the orbiter's main landing gear door. The inspection is a precautionary measure after a small crack was found in a retract link assembly on the right-hand main landing gear on orbiter Atlantis. An initial review of the closeout photos of the link assembly on Discovery did not reveal any cracks. Discovery is scheduled to return the Space Shuttle fleet to operational status on mission STS-114. This additional work does not impact the launch planning window of July 13-31.

KSC01KODI035

NASA Image and Video Library

2001-05-29

KODIAK ISLAND, Alaska -- A special platform connects the barge with a ramp to allow Castor 120, the first stage of the Athena 1 launch vehicle, to safely move onto the dock at Kodiak Island, Alaska, as preparations to launch Kodiak Star proceed. The first orbital launch to take place from Alaska's Kodiak Launch Complex, Kodiak Star is scheduled to lift off on a Lockheed Martin Athena I launch vehicle on Sept. 17 during a two-hour window that extends from 5:00 to 7:00 p.m. ADT. The payloads aboard include the Starshine 3, sponsored by NASA, and the PICOSat, PCSat and Sapphire, sponsored by the Department of Defense (DoD) Space Test Program.

Digital Image Correlation Engine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turner, Dan; Crozier, Paul; Reu, Phil

DICe is an open source digital image correlation (DIC) tool intended for use as a module in an external application or as a standalone analysis code. It's primary capability is computing full-field displacements and strains from sequences of digital These images are typically of a material sample undergoing a materials characterization experiment, but DICe is also useful for other applications (for example, trajectory tracking). DICe is machine portable (Windows, Linux and Mac) and can be effectively deployed on a high performance computing platform. Capabilities from DICe can be invoked through a library interface, via source code integration of DICe classesmore » or through a graphical user interface.« less

Reconfigurable Mobile System - Ground, sea and air applications

NASA Astrophysics Data System (ADS)

Lamonica, Gary L.; Sturges, James W.

1990-11-01

The Reconfigurable Mobile System (RMS) is a highly mobile data-processing unit for military users requiring real-time access to data gathered by airborne (and other) reconnaissance data. RMS combines high-performance computation and image processing workstations with resources for command/control/communications in a single, lightweight shelter. RMS is composed of off-the-shelf components, and is easily reconfigurable to land-vehicle or shipboard versions. Mission planning, which involves an airborne sensor platform's sensor coverage, considered aircraft/sensor capabilities in conjunction with weather, terrain, and threat scenarios. RMS's man-machine interface concept facilitates user familiarization and features iron-based function selection and windowing.

Two-step ion-exchange chromatographic purification combined with reversed-phase chromatography to isolate C-peptide for mass spectrometric analysis.

PubMed

Kabytaev, Kuanysh; Durairaj, Anita; Shin, Dmitriy; Rohlfing, Curt L; Connolly, Shawn; Little, Randie R; Stoyanov, Alexander V

2016-02-01

A liquid chromatography with mass spectrometry on-line platform that includes the orthogonal techniques of ion exchange and reversed phase chromatography is applied for C-peptide analysis. Additional improvement is achieved by the subsequent application of cation- and anion-exchange purification steps that allow for isolating components that have their isoelectric points in a narrow pH range before final reversed-phase mass spectrometry analysis. The utility of this approach for isolating fractions in the desired "pI window" for profiling complex mixtures is discussed. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

NREL's OpenStudio Helps Design More Efficient Buildings (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2014-07-01

The National Renewable Energy Laboratory (NREL) has created the OpenStudio software platform that makes it easier for architects and engineers to evaluate building energy efficiency measures throughout the design process. OpenStudio makes energy modeling more accessible and affordable, helping professionals to design structures with lower utility bills and less carbon emissions, resulting in a healthier environment. OpenStudio includes a user-friendly application suite that makes the U.S. Department of Energy's EnergyPlus and Radiance simulation engines easier to use for whole building energy and daylighting performance analysis. OpenStudio is freely available and runs on Windows, Mac, and Linux operating systems.

Telescience Resource Kit (TReK)

NASA Technical Reports Server (NTRS)

Lippincott, Jeff

2015-01-01

Telescience Resource Kit (TReK) is one of the Huntsville Operations Support Center (HOSC) remote operations solutions. It can be used to monitor and control International Space Station (ISS) payloads from anywhere in the world. It is comprised of a suite of software applications and libraries that provide generic data system capabilities and access to HOSC services. The TReK Software has been operational since 2000. A new cross-platform version of TReK is under development. The new software is being released in phases during the 2014-2016 timeframe. The TReK Release 3.x series of software is the original TReK software that has been operational since 2000. This software runs on Windows. It contains capabilities to support traditional telemetry and commanding using CCSDS (Consultative Committee for Space Data Systems) packets. The TReK Release 4.x series of software is the new cross platform software. It runs on Windows and Linux. The new TReK software will support communication using standard IP protocols and traditional telemetry and commanding. All the software listed above is compatible and can be installed and run together on Windows. The new TReK software contains a suite of software that can be used by payload developers on the ground and onboard (TReK Toolkit). TReK Toolkit is a suite of lightweight libraries and utility applications for use onboard and on the ground. TReK Desktop is the full suite of TReK software -most useful on the ground. When TReK Desktop is released, the TReK installation program will provide the option to choose just the TReK Toolkit portion of the software or the full TReK Desktop suite. The ISS program is providing the TReK Toolkit software as a generic flight software capability offered as a standard service to payloads. TReK Software Verification was conducted during the April/May 2015 timeframe. Payload teams using the TReK software onboard can reference the TReK software verification. TReK will be demonstrated on-orbit running on an ISS provided T61p laptop. Target Timeframe: September 2015 -2016. The on-orbit demonstration will collect benchmark metrics, and will be used in the future to provide live demonstrations during ISS Payload Conferences. Benchmark metrics and demonstrations will address the protocols described in SSP 52050-0047 Ku Forward section 3.3.7. (Associated term: CCSDS File Delivery Protocol (CFDP)).

Optimization of image processing algorithms on mobile platforms

NASA Astrophysics Data System (ADS)

Poudel, Pramod; Shirvaikar, Mukul

2011-03-01

This work presents a technique to optimize popular image processing algorithms on mobile platforms such as cell phones, net-books and personal digital assistants (PDAs). The increasing demand for video applications like context-aware computing on mobile embedded systems requires the use of computationally intensive image processing algorithms. The system engineer has a mandate to optimize them so as to meet real-time deadlines. A methodology to take advantage of the asymmetric dual-core processor, which includes an ARM and a DSP core supported by shared memory, is presented with implementation details. The target platform chosen is the popular OMAP 3530 processor for embedded media systems. It has an asymmetric dual-core architecture with an ARM Cortex-A8 and a TMS320C64x Digital Signal Processor (DSP). The development platform was the BeagleBoard with 256 MB of NAND RAM and 256 MB SDRAM memory. The basic image correlation algorithm is chosen for benchmarking as it finds widespread application for various template matching tasks such as face-recognition. The basic algorithm prototypes conform to OpenCV, a popular computer vision library. OpenCV algorithms can be easily ported to the ARM core which runs a popular operating system such as Linux or Windows CE. However, the DSP is architecturally more efficient at handling DFT algorithms. The algorithms are tested on a variety of images and performance results are presented measuring the speedup obtained due to dual-core implementation. A major advantage of this approach is that it allows the ARM processor to perform important real-time tasks, while the DSP addresses performance-hungry algorithms.

A customizable commercial miniaturized 320×256 indium gallium arsenide shortwave infrared camera

NASA Astrophysics Data System (ADS)

Huang, Shih-Che; O'Grady, Matthew; Groppe, Joseph V.; Ettenberg, Martin H.; Brubaker, Robert M.

2004-10-01

The design and performance of a commercial short-wave-infrared (SWIR) InGaAs microcamera engine is presented. The 0.9-to-1.7 micron SWIR imaging system consists of a room-temperature-TEC-stabilized, 320x256 (25 μm pitch) InGaAs focal plane array (FPA) and a high-performance, highly customizable image-processing set of electronics. The detectivity, D*, of the system is greater than 1013 cm-√Hz/W at 1.55 μm, and this sensitivity may be adjusted in real-time over 100 dB. It features snapshot-mode integration with a minimum exposure time of 130 μs. The digital video processor provides real time pixel-to-pixel, 2-point dark-current subtraction and non-uniformity compensation along with defective-pixel substitution. Other features include automatic gain control (AGC), gamma correction, 7 preset configurations, adjustable exposure time, external triggering, and windowing. The windowing feature is highly flexible; the region of interest (ROI) may be placed anywhere on the imager and can be varied at will. Windowing allows for high-speed readout enabling such applications as target acquisition and tracking; for example, a 32x32 ROI window may be read out at over 3500 frames per second (fps). Output video is provided as EIA170-compatible analog, or as 12-bit CameraLink-compatible digital. All the above features are accomplished in a small volume < 28 cm3, weight < 70 g, and with low power consumption < 1.3 W at room temperature using this new microcamera engine. Video processing is based on a field-programmable gate array (FPGA) platform with a soft-embedded processor that allows for ease of integration/addition of customer-specific algorithms, processes, or design requirements. The camera was developed with the high-performance, space-restricted, power-conscious application in mind, such as robotic or UAV deployment.

High durability antireflection coatings for silicon and multispectral ZnS

NASA Astrophysics Data System (ADS)

Joseph, Shay; Marcovitch, Orna; Yadin, Ygal; Klaiman, Dror; Koren, Nitzan; Zipin, Hedva

2007-04-01

In the current complex battle field, military platforms are required to operate on land, at sea and in the air in all weather conditions both day and night. In order to achieve such capabilities, advanced electro-optical systems are being constantly developed and improved. These systems such as missile seeker heads, reconnaissance and target acquisition pods and tracking, monitoring and alert systems have external optical components (window or dome) which must remain operational even at extreme environmental conditions. Depending on the intended use of the system, there are a few choices of window and dome materials. Amongst the more common materials one can point out sapphire, ZnS, germanium and silicon. Other materials such as spinel, ALON and yittria may also be considered. Most infrared materials have high indices of refraction and therefore they reflect a large part of radiation. To minimize the reflection and increase the transmission, antireflection (AR) coatings are the most common choice. Since these systems operate at different environments and weather conditions, the coatings must be made durable to withstand these extreme conditions. In cases where the window or dome is made of relatively soft materials such as multispectral ZnS, the coating may also serve as protection for the window or dome. In this work, several antireflection coatings have been designed and manufactured for silicon and multispectral ZnS. The coating materials were chosen to be either oxides or fluorides which are known to have high durability. Ellipsometry measurements were used to characterize the optical constants of the thin films. The effects of the deposition conditions on the optical constants of the deposited thin films and durability of the coatings will be discussed. The coatings were tested according to MIL-STD-810E and were also subjected to rain erosion tests at the University of Dayton Research Institute (UDRI) whirling arm apparatus in which one of the coatings showed no rain drop impact damage at all.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ravindran, P; Wui Ann, W; Lim, Y

Purpose: In general, the linear accelerator is gated using respiratory signal obtained by way of external sensors to account for the breathing motion during radiotherapy. One of the commonly used gating devices is the Varian RPM device. Calypso system that uses electromagnetic tracking of implanted or surface transponders could also be used for gating. The aim of this study is to compare the gating efficiency of RPM device and the calypso system by phantom studies. Methods: An ArcCheck insert was used as the phantom with a Gafchromic film placed in its holder. The ArcCheck insert was placed on a Motionmore » Sim platform and moved in the longitudinal direction simulating a respiratory motion with a period of 5 seconds and amplitude of ±6mm. The Gafchromic film was exposed to a 2 × 2cm{sup 2} field, i) with the phantom static, ii) phantom moving but ungated iii) gated with gating window of 2mm and 3mm. This was repeated with Calypso system using surface transponders with the same gating window. The Gafchromic films were read with an EPSON 11000 flatbed scanner and analysed with ‘Medphysto’ software. Results: The full width at half maximum (FWHM) as measured with film at the level of the film holder was 1.65cm when the phantom was static. FWHM measured with phantom moving and without gating was 1.16 cm and penumbra was 7 mm (80–20%) on both sides. When the beam was gated with 2 mm gating window the FWHM was 1.8 cm with RPM device and 1.9 cm with Calypso. Similarly, when the beam was gated with 3 mm window, the FWHM was 1.9cm with RPM device and 2cm with Calypso. Conclusion: This work suggests that the gating efficiency of RPM device is better than that of the Calypso with surface transponder, with reference to the latency in gating.« less

Estimating optically-thin cirrus cloud induced cold bias on infrared radiometric satellite sea surface temperature retrieval in the tropics

NASA Astrophysics Data System (ADS)

Marquis, Jared Wayne

Passive longwave infrared radiometric satellite-based retrievals of sea surface temperature (SST) at instrument nadir are investigated for cold bias caused by unscreened optically-thin cirrus (OTC) clouds (cloud optical depth ≤ 0.3; COD). Level 2 split-window SST retrievals over tropical oceans (30° S - 30° N) from Moderate Resolution Imaging Spectroradiometer (MODIS) radiances collected aboard the NASA Aqua satellite (Aqua-MODIS) are collocated with cloud profiles from the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) instrument, mounted on the independent NASA CALIPSO satellite. OTC are present in approximately 25% of tropical quality-assured (QA) Aqua-MODIS Level-2 data, representing over 99% of all contaminating cirrus found. This results in cold-biased SST retrievals using either split- (MODIS, AVHRR and VIIRS) or triple-window (AVHRR and VIIRS only) retrieval methods. SST retrievals are modeled based on operational algorithms using radiative transfer model simulations conducted with a hypothetical 1.5 km thick OTC cloud placed incrementally from 10.0 - 18.0 km above mean sea level for cloud optical depths (COD) between 0.0 - 0.3. Corresponding cold bias estimates for each sensor are estimated using relative Aqua-MODIS cloud contamination frequencies as a function of cloud top height and COD (assuming them consistent across each platform) integrated within each corresponding modeled cold bias matrix. Split-window relative OTC cold biases, for any single observation, range from 0.40° - 0.49° C for the three sensors, with an absolute (bulk mean) bias between 0.10° - 0.13° C. Triple-window retrievals are more resilient, ranging from 0.03° - 0.04° C relative and 0.11° - 0.16° C absolute. Cold biases are constant across the Pacific and Indian Ocean domains. Absolute bias is smaller over the Atlantic, but relative bias is larger due to different cloud properties indicating that this issue persists globally.

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

PubMed Central

Kearse, Matthew; Moir, Richard; Wilson, Amy; Stones-Havas, Steven; Cheung, Matthew; Sturrock, Shane; Buxton, Simon; Cooper, Alex; Markowitz, Sidney; Duran, Chris; Thierer, Tobias; Ashton, Bruce; Meintjes, Peter; Drummond, Alexei

2012-01-01

Summary: The two main functions of bioinformatics are the organization and analysis of biological data using computational resources. Geneious Basic has been designed to be an easy-to-use and flexible desktop software application framework for the organization and analysis of biological data, with a focus on molecular sequences and related data types. It integrates numerous industry-standard discovery analysis tools, with interactive visualizations to generate publication-ready images. One key contribution to researchers in the life sciences is the Geneious public application programming interface (API) that affords the ability to leverage the existing framework of the Geneious Basic software platform for virtually unlimited extension and customization. The result is an increase in the speed and quality of development of computation tools for the life sciences, due to the functionality and graphical user interface available to the developer through the public API. Geneious Basic represents an ideal platform for the bioinformatics community to leverage existing components and to integrate their own specific requirements for the discovery, analysis and visualization of biological data. Availability and implementation: Binaries and public API freely available for download at http://www.geneious.com/basic, implemented in Java and supported on Linux, Apple OSX and MS Windows. The software is also available from the Bio-Linux package repository at http://nebc.nerc.ac.uk/news/geneiousonbl. Contact: peter@biomatters.com PMID:22543367

Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data.

PubMed

Kearse, Matthew; Moir, Richard; Wilson, Amy; Stones-Havas, Steven; Cheung, Matthew; Sturrock, Shane; Buxton, Simon; Cooper, Alex; Markowitz, Sidney; Duran, Chris; Thierer, Tobias; Ashton, Bruce; Meintjes, Peter; Drummond, Alexei

2012-06-15

The two main functions of bioinformatics are the organization and analysis of biological data using computational resources. Geneious Basic has been designed to be an easy-to-use and flexible desktop software application framework for the organization and analysis of biological data, with a focus on molecular sequences and related data types. It integrates numerous industry-standard discovery analysis tools, with interactive visualizations to generate publication-ready images. One key contribution to researchers in the life sciences is the Geneious public application programming interface (API) that affords the ability to leverage the existing framework of the Geneious Basic software platform for virtually unlimited extension and customization. The result is an increase in the speed and quality of development of computation tools for the life sciences, due to the functionality and graphical user interface available to the developer through the public API. Geneious Basic represents an ideal platform for the bioinformatics community to leverage existing components and to integrate their own specific requirements for the discovery, analysis and visualization of biological data. Binaries and public API freely available for download at http://www.geneious.com/basic, implemented in Java and supported on Linux, Apple OSX and MS Windows. The software is also available from the Bio-Linux package repository at http://nebc.nerc.ac.uk/news/geneiousonbl.

Dual-Spectroscopy Platform for the Surveillance of Mars Mineralogy Using a Decisions Fusion Architecture on Simultaneous LIBS-Raman Data.

PubMed

Moros, Javier; ElFaham, Mohamed Mostafa; Laserna, J Javier

2018-02-06

A single platform, integrated by a laser-induced breakdown spectroscopy detector and a Raman spectroscopy sensor, has been designed to remotely (5 m) and simultaneously register the elemental and molecular signatures of rocks under Martian surface conditions. From this information, new data fusion architecture at decisions level is proposed for the correct categorization of the rocks. The approach is based on a decision-making process from the sequential checking of the spectral features representing the cationic and anionic counterparts of the specimen. The scrutiny of the LIBS response by using a moving-window algorithm informs on the diversity of the elemental constituents. The output rate of emission lines allows projecting in a loop the elements as the cationic counterpart of the rock. In parallel, the Raman response of the unknown is compared with all the molecular counterparts of the hypothesized cation that are stored in a spectral library. The largest similarity rate unveils the final identity of the unknown. The identification capabilities of the architecture have been underscored through blind tests of 10 natural rocks with different origins. The great majority of forecasts have matched with the real identities of the inspected targets. The strength of this platform to simultaneously acquire the multielemental and the molecular information from a specimen by using the same laser events greatly enhances the "on-surface" missions for the surveillance of mineralogy.

European health telematics networks for positron emission tomography

NASA Astrophysics Data System (ADS)

Kontaxakis, George; Pozo, Miguel Angel; Ohl, Roland; Visvikis, Dimitris; Sachpazidis, Ilias; Ortega, Fernando; Guerra, Pedro; Cheze-Le Rest, Catherine; Selby, Peter; Pan, Leyun; Diaz, Javier; Dimitrakopoulou-Strauss, Antonia; Santos, Andres; Strauss, Ludwig; Sakas, Georgios

2006-12-01

A pilot network of positron emission tomography centers across Europe has been setup employing telemedicine services. The primary aim is to bring all PET centers in Europe (and beyond) closer, by integrating advanced medical imaging technology and health telematics networks applications into a single, easy to operate health telematics platform, which allows secure transmission of medical data via a variety of telecommunications channels and fosters the cooperation between professionals in the field. The platform runs on PCs with Windows 2000/XP and incorporates advanced techniques for image visualization, analysis and fusion. The communication between two connected workstations is based on a TCP/IP connection secured by secure socket layers and virtual private network or jabber protocols. A teleconsultation can be online (with both physicians physically present) or offline (via transmission of messages which contain image data and other information). An interface sharing protocol enables online teleconsultations even over low bandwidth connections. This initiative promotes the cooperation and improved communication between nuclear medicine professionals, offering options for second opinion and training. It permits physicians to remotely consult patient data, even if they are away from the physical examination site.

"Just Another Tool for Online Studies” (JATOS): An Easy Solution for Setup and Management of Web Servers Supporting Online Studies

PubMed Central

Lange, Kristian; Kühn, Simone; Filevich, Elisa

2015-01-01

We present here “Just Another Tool for Online Studies” (JATOS): an open source, cross-platform web application with a graphical user interface (GUI) that greatly simplifies setting up and communicating with a web server to host online studies that are written in JavaScript. JATOS is easy to install in all three major platforms (Microsoft Windows, Mac OS X, and Linux), and seamlessly pairs with a database for secure data storage. It can be installed on a server or locally, allowing researchers to try the application and feasibility of their studies within a browser environment, before engaging in setting up a server. All communication with the JATOS server takes place via a GUI (with no need to use a command line interface), making JATOS an especially accessible tool for researchers without a strong IT background. We describe JATOS’ main features and implementation and provide a detailed tutorial along with example studies to help interested researchers to set up their online studies. JATOS can be found under the Internet address: www.jatos.org. PMID:26114751

Geomorphology Classification of Shandong Province Based on Digital Elevation Model in the 1 Arc-second Format of Shuttle Radar Topography Mission Data

NASA Astrophysics Data System (ADS)

Fu, Jundong; Zhang, Guangcheng; Wang, Lei; Xia, Nuan

2018-01-01

Based on gigital elevation model in the 1 arc-second format of shuttle radar topography mission data, using the window analysis and mean change point analysis of geographic information system (GIS) technology, programmed with python modules this, automatically extracted and calculated geomorphic elements of Shandong province. The best access to quantitatively study area relief amplitude of statistical area. According to Chinese landscape classification standard, the landscape type in Shandong province was divided into 8 types: low altitude plain, medium altitude plain, low altitude platform, medium altitude platform, low altitude hills, medium altitude hills, low relief mountain, medium relief mountain and the percentages of Shandong province’s total area are as follows: 12.72%, 0.01%, 36.38%, 0.24%, 17.26%, 15.64%, 11.1%, 6.65%. The results of landforms are basically the same as the overall terrain of Shandong Province, Shandong province’s total area, and the study can quantitatively and scientifically provide reference for the classification of landforms in Shandong province.

PlaIMoS: A Remote Mobile Healthcare Platform to Monitor Cardiovascular and Respiratory Variables

PubMed Central

Miramontes, Ramses; Aquino, Raúl; Flores, Arturo; Rodríguez, Guillermo; Anguiano, Rafael; Ríos, Arturo; Edwards, Arthur

2017-01-01

The number of elderly and chronically ill patients has grown significantly over the past few decades as life expectancy has increased worldwide, leading to increased demands on the health care system and significantly taxing traditional health care practices. Consequently, there is an urgent need to use technology to innovate and more constantly and intensely monitor, report and analyze critical patient physiological parameters beyond conventional clinical settings in a more efficient and cost effective manner. This paper presents a technological platform called PlaIMoS which consists of wearable sensors, a fixed measurement station, a network infrastructure that employs IEEE 802.15.4 and IEEE 802.11 to transmit data with security mechanisms, a server to analyze all information collected and apps for iOS, Android and Windows 10 mobile operating systems to provide real-time measurements. The developed architecture, designed primarily to record and report electrocardiogram and heart rate data, also monitors parameters associated with chronic respiratory illnesses, including patient blood oxygen saturation and respiration rate, body temperature, fall detection and galvanic resistance. PMID:28106832

compendiumdb: an R package for retrieval and storage of functional genomics data.

PubMed

Nandal, Umesh K; van Kampen, Antoine H C; Moerland, Perry D

2016-09-15

Currently, the Gene Expression Omnibus (GEO) contains public data of over 1 million samples from more than 40 000 microarray-based functional genomics experiments. This provides a rich source of information for novel biological discoveries. However, unlocking this potential often requires retrieving and storing a large number of expression profiles from a wide range of different studies and platforms. The compendiumdb R package provides an environment for downloading functional genomics data from GEO, parsing the information into a local or remote database and interacting with the database using dedicated R functions, thus enabling seamless integration with other tools available in R/Bioconductor. The compendiumdb package is written in R, MySQL and Perl. Source code and binaries are available from CRAN (http://cran.r-project.org/web/packages/compendiumdb/) for all major platforms (Linux, MS Windows and OS X) under the GPLv3 license. p.d.moerland@amc.uva.nl Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

PlaIMoS: A Remote Mobile Healthcare Platform to Monitor Cardiovascular and Respiratory Variables.

PubMed

Miramontes, Ramses; Aquino, Raúl; Flores, Arturo; Rodríguez, Guillermo; Anguiano, Rafael; Ríos, Arturo; Edwards, Arthur

2017-01-19

The number of elderly and chronically ill patients has grown significantly over the past few decades as life expectancy has increased worldwide, leading to increased demands on the health care system and significantly taxing traditional health care practices. Consequently, there is an urgent need to use technology to innovate and more constantly and intensely monitor, report and analyze critical patient physiological parameters beyond conventional clinical settings in a more efficient and cost effective manner. This paper presents a technological platform called PlaIMoS which consists of wearable sensors, a fixed measurement station, a network infrastructure that employs IEEE 802.15.4 and IEEE 802.11 to transmit data with security mechanisms, a server to analyze all information collected and apps for iOS, Android and Windows 10 mobile operating systems to provide real-time measurements. The developed architecture, designed primarily to record and report electrocardiogram and heart rate data, also monitors parameters associated with chronic respiratory illnesses, including patient blood oxygen saturation and respiration rate, body temperature, fall detection and galvanic resistance.

Worldwide Telescope as an earth and planetary science educational platform

NASA Astrophysics Data System (ADS)

Fatland, D. R.; Rush, K.; van Ingen, C.; Wong, C.; Fay, J.; Xu, Y.; Fay, D.

2009-12-01

Worldwide Telescope (WWT) -available at no cost from Microsoft Research as both Windows desktop and web browser applications - enables personal computers to function as virtual telescopes for viewing the earth, the solar system and the cosmos across many wavelengths. Bringing together imagery from ground and space-based telescopes as well as photography from Mars rovers and Apollo astronauts, WWT is designed to work as both a research tool and a platform for educational exploration. Central to the latter purpose is the Tour authoring facility which enables a student or educator to create narrative stories with dynamic perspective, voice-over narrative, background sound and superimposed content. We describe here the application of recent developments in WWT, particularly the 2009 updates, towards planetary science education with particular emphasis on WWT earth models. Two core themes informing this development are the notions of enabling social networking through WWT Communities and including the earth as part of the bigger picture, in effect swinging the telescope around from the deep sky to look back at our observatory. moon, earth (WWT solar system view)

An adaptable navigation strategy for Virtual Microscopy from mobile platforms.

PubMed

Corredor, Germán; Romero, Eduardo; Iregui, Marcela

2015-04-01

Real integration of Virtual Microscopy with the pathologist service workflow requires the design of adaptable strategies for any hospital service to interact with a set of Whole Slide Images. Nowadays, mobile devices have the actual potential of supporting an online pervasive network of specialists working together. However, such devices are still very limited. This article introduces a novel highly adaptable strategy for streaming and visualizing WSI from mobile devices. The presented approach effectively exploits and extends the granularity of the JPEG2000 standard and integrates it with different strategies to achieve a lossless, loosely-coupled, decoder and platform independent implementation, adaptable to any interaction model. The performance was evaluated by two expert pathologists interacting with a set of 20 virtual slides. The method efficiently uses the available device resources: the memory usage did not exceed a 7% of the device capacity while the decoding times were smaller than the 200 ms per Region of Interest, i.e., a window of 256×256 pixels. This model is easily adaptable to other medical imaging scenarios. Copyright © 2015 Elsevier Inc. All rights reserved.

A Remote Health Monitoring System for the Elderly Based on Smart Home Gateway

PubMed Central

Shao, Minggang

2017-01-01

This paper proposed a remote health monitoring system for the elderly based on smart home gateway. The proposed system consists of three parts: the smart clothing, the smart home gateway, and the health care server. The smart clothing collects the elderly's electrocardiogram (ECG) and motion signals. The home gateway is used for data transmission. The health care server provides services of data storage and user information management; it is constructed on the Windows-Apache-MySQL-PHP (WAMP) platform and is tested on the Ali Cloud platform. To resolve the issues of data overload and network congestion of the home gateway, an ECG compression algorithm is applied. System demonstration shows that the ECG signals and motion signals of the elderly can be monitored. Evaluation of the compression algorithm shows that it has a high compression ratio and low distortion and consumes little time, which is suitable for home gateways. The proposed system has good scalability, and it is simple to operate. It has the potential to provide long-term and continuous home health monitoring services for the elderly. PMID:29204258

A Remote Health Monitoring System for the Elderly Based on Smart Home Gateway.

PubMed

Guan, Kai; Shao, Minggang; Wu, Shuicai

2017-01-01

This paper proposed a remote health monitoring system for the elderly based on smart home gateway. The proposed system consists of three parts: the smart clothing, the smart home gateway, and the health care server. The smart clothing collects the elderly's electrocardiogram (ECG) and motion signals. The home gateway is used for data transmission. The health care server provides services of data storage and user information management; it is constructed on the Windows-Apache-MySQL-PHP (WAMP) platform and is tested on the Ali Cloud platform. To resolve the issues of data overload and network congestion of the home gateway, an ECG compression algorithm is applied. System demonstration shows that the ECG signals and motion signals of the elderly can be monitored. Evaluation of the compression algorithm shows that it has a high compression ratio and low distortion and consumes little time, which is suitable for home gateways. The proposed system has good scalability, and it is simple to operate. It has the potential to provide long-term and continuous home health monitoring services for the elderly.

Update on PISCES

NASA Technical Reports Server (NTRS)

Pearson, Don; Hamm, Dustin; Kubena, Brian; Weaver, Jonathan K.

2010-01-01

An updated version of the Platform Independent Software Components for the Exploration of Space (PISCES) software library is available. A previous version was reported in Library for Developing Spacecraft-Mission-Planning Software (MSC-22983), NASA Tech Briefs, Vol. 25, No. 7 (July 2001), page 52. To recapitulate: This software provides for Web-based, collaborative development of computer programs for planning trajectories and trajectory- related aspects of spacecraft-mission design. The library was built using state-of-the-art object-oriented concepts and software-development methodologies. The components of PISCES include Java-language application programs arranged in a hierarchy of classes that facilitates the reuse of the components. As its full name suggests, the PISCES library affords platform-independence: The Java language makes it possible to use the classes and application programs with a Java virtual machine, which is available in most Web-browser programs. Another advantage is expandability: Object orientation facilitates expansion of the library through creation of a new class. Improvements in the library since the previous version include development of orbital-maneuver- planning and rendezvous-launch-window application programs, enhancement of capabilities for propagation of orbits, and development of a desktop user interface.

Research on propane leak detection system and device based on mid infrared laser

NASA Astrophysics Data System (ADS)

Jiang, Meng; Wang, Xuefeng; Wang, Junlong; Wang, Yizhao; Li, Pan; Feng, Qiaoling

2017-10-01

Propane is a key component of liquefied petroleum gas (LPG) and crude oil volatile. This issue summarizes the recent progress of propane detection technology. Meanwhile, base on the development trend, our latest progress is also provided. We demonstrated a mid infrared propane sensor system, which is based on wavelength modulation spectroscopy (WMS) technique with a CW interband cascade laser (ICL) emitting at 3370.4nm. The ICL laser scanned over a sharp feature in the broader spectrum of propane, and harmonic signals are obtained by lock-in amplifier for gas concentration deduction. The surrounding gas is extracted into the fine optical absorption cell through the pump to realize online detection. The absorption cell is designed in mid infrared windows range. An example experimental setup is shown. The second harmonic signals 2f and first harmonic signals1f are obtained. We present the sensor performance test data including dynamic precision and temperature stability. The propane detection sensor system and device is portable can carried on the mobile inspection vehicle platforms or intelligent robot inspection platform to realize the leakage monitoring of whole oil gas tank area.

KSC-06pd1710

NASA Image and Video Library

2006-08-02

KENNEDY SPACE CENTER, FLA. - In the bright light of day, Space Shuttle Atlantis nears the hard stand on Launch Pad 39B. First motion out of the Vehicle Assembly Building was 1:05 a.m. The shuttle sits on top of the mobile launcher platform, which in turn rests on the crawler-transporter. At right is the 290-foot high, 300,000- gallon water tank that aids in sound suppression during launch. The water releases just prior to the ignition of the shuttle engines and flows through 7-foot-diameter pipes for about 20 seconds, pouring into 16 nozzles atop the flame deflectors and from outlets in the main engines exhaust hole in the mobile launcher platform. The slow speed of the crawler results in a 6-hour trek to the pad approximately 4 miles away. Atlantis' launch window begins Aug. 27 for an 11-day mission to the International Space Station. The STS-115 crew of six astronauts will continue construction of the station and install their cargo, the Port 3/4 truss segment with its two large solar arrays. Photo credit: NASA/Troy Cryder

Facilitating NASA Earth Science Data Processing Using Nebula Cloud Computing

NASA Astrophysics Data System (ADS)

Chen, A.; Pham, L.; Kempler, S.; Theobald, M.; Esfandiari, A.; Campino, J.; Vollmer, B.; Lynnes, C.

2011-12-01

Cloud Computing technology has been used to offer high-performance and low-cost computing and storage resources for both scientific problems and business services. Several cloud computing services have been implemented in the commercial arena, e.g. Amazon's EC2 & S3, Microsoft's Azure, and Google App Engine. There are also some research and application programs being launched in academia and governments to utilize Cloud Computing. NASA launched the Nebula Cloud Computing platform in 2008, which is an Infrastructure as a Service (IaaS) to deliver on-demand distributed virtual computers. Nebula users can receive required computing resources as a fully outsourced service. NASA Goddard Earth Science Data and Information Service Center (GES DISC) migrated several GES DISC's applications to the Nebula as a proof of concept, including: a) The Simple, Scalable, Script-based Science Processor for Measurements (S4PM) for processing scientific data; b) the Atmospheric Infrared Sounder (AIRS) data process workflow for processing AIRS raw data; and c) the GES-DISC Interactive Online Visualization ANd aNalysis Infrastructure (GIOVANNI) for online access to, analysis, and visualization of Earth science data. This work aims to evaluate the practicability and adaptability of the Nebula. The initial work focused on the AIRS data process workflow to evaluate the Nebula. The AIRS data process workflow consists of a series of algorithms being used to process raw AIRS level 0 data and output AIRS level 2 geophysical retrievals. Migrating the entire workflow to the Nebula platform is challenging, but practicable. After installing several supporting libraries and the processing code itself, the workflow is able to process AIRS data in a similar fashion to its current (non-cloud) configuration. We compared the performance of processing 2 days of AIRS level 0 data through level 2 using a Nebula virtual computer and a local Linux computer. The result shows that Nebula has significantly better performance than the local machine. Much of the difference was due to newer equipment in the Nebula than the legacy computer, which is suggestive of a potential economic advantage beyond elastic power, i.e., access to up-to-date hardware vs. legacy hardware that must be maintained past its prime to amortize the cost. In addition to a trade study of advantages and challenges of porting complex processing to the cloud, a tutorial was developed to enable further progress in utilizing the Nebula for Earth Science applications and understanding better the potential for Cloud Computing in further data- and computing-intensive Earth Science research. In particular, highly bursty computing such as that experienced in the user-demand-driven Giovanni system may become more tractable in a Cloud environment. Our future work will continue to focus on migrating more GES DISC's applications/instances, e.g. Giovanni instances, to the Nebula platform and making matured migrated applications to be in operation on the Nebula.

Real-Time Social Data Collection in Rural Bangladesh via a ‘Microtasks for Micropayments’ Platform on Android Smartphones

PubMed Central

Ward, Patrick S.; Killilea, Mary E.; Tamal, Md. Ehsanul Haque

2016-01-01

The advent of cheap smartphones in rural areas across the globe presents an opportunity to change the mode with which researchers engage hard-to-reach populations. In particular, smartphones allow researchers to connect with respondents more frequently than standard household surveys, opening a new window into important short-term variability in key measures of household and community wellbeing. In this paper, we present early results from a pilot study in rural Bangladesh using a ‘microtasks for micropayments’ model to collect a range of community and household living standards data using Android smartphones. We find that more frequent task repetition with shorter recall periods leads to more inclusive reporting, improved capture of intra-seasonal variability, and earlier signals of events such as illness. Payments in the form of mobile talk time and data provide a positive development externality in the form of expanded access to mobile internet and social networks. Taken to scale, programs such as this have potential to transform data collection in rural areas, providing near-real-time windows into the development of markets, the spread of illnesses, or the diffusion of ideas and innovations. PMID:27832116

PPP Sliding Window Algorithm and Its Application in Deformation Monitoring.

PubMed

Song, Weiwei; Zhang, Rui; Yao, Yibin; Liu, Yanyan; Hu, Yuming

2016-05-31

Compared with the double-difference relative positioning method, the precise point positioning (PPP) algorithm can avoid the selection of a static reference station and directly measure the three-dimensional position changes at the observation site and exhibit superiority in a variety of deformation monitoring applications. However, because of the influence of various observing errors, the accuracy of PPP is generally at the cm-dm level, which cannot meet the requirements needed for high precision deformation monitoring. For most of the monitoring applications, the observation stations maintain stationary, which can be provided as a priori constraint information. In this paper, a new PPP algorithm based on a sliding window was proposed to improve the positioning accuracy. Firstly, data from IGS tracking station was processed using both traditional and new PPP algorithm; the results showed that the new algorithm can effectively improve positioning accuracy, especially for the elevation direction. Then, an earthquake simulation platform was used to simulate an earthquake event; the results illustrated that the new algorithm can effectively detect the vibrations change of a reference station during an earthquake. At last, the observed Wenchuan earthquake experimental results showed that the new algorithm was feasible to monitor the real earthquakes and provide early-warning alerts.

Real-Time Social Data Collection in Rural Bangladesh via a 'Microtasks for Micropayments' Platform on Android Smartphones.

PubMed

Bell, Andrew Reid; Ward, Patrick S; Killilea, Mary E; Tamal, Md Ehsanul Haque

2016-01-01

The advent of cheap smartphones in rural areas across the globe presents an opportunity to change the mode with which researchers engage hard-to-reach populations. In particular, smartphones allow researchers to connect with respondents more frequently than standard household surveys, opening a new window into important short-term variability in key measures of household and community wellbeing. In this paper, we present early results from a pilot study in rural Bangladesh using a 'microtasks for micropayments' model to collect a range of community and household living standards data using Android smartphones. We find that more frequent task repetition with shorter recall periods leads to more inclusive reporting, improved capture of intra-seasonal variability, and earlier signals of events such as illness. Payments in the form of mobile talk time and data provide a positive development externality in the form of expanded access to mobile internet and social networks. Taken to scale, programs such as this have potential to transform data collection in rural areas, providing near-real-time windows into the development of markets, the spread of illnesses, or the diffusion of ideas and innovations.

Electronic Health Record for Intensive Care based on Usual Windows Based Software.

PubMed

Reper, Arnaud; Reper, Pascal

2015-08-01

In Intensive Care Units, the amount of data to be processed for patients care, the turn over of the patients, the necessity for reliability and for review processes indicate the use of Patient Data Management Systems (PDMS) and electronic health records (EHR). To respond to the needs of an Intensive Care Unit and not to be locked with proprietary software, we developed an EHR based on usual software and components. The software was designed as a client-server architecture running on the Windows operating system and powered by the access data base system. The client software was developed using Visual Basic interface library. The application offers to the users the following functions: medical notes captures, observations and treatments, nursing charts with administration of medications, scoring systems for classification, and possibilities to encode medical activities for billing processes. Since his deployment in September 2004, the EHR was used to care more than five thousands patients with the expected software reliability and facilitated data management and review processes. Communications with other medical software were not developed from the start, and are realized by the use of basic functionalities communication engine. Further upgrade of the system will include multi-platform support, use of typed language with static analysis, and configurable interface. The developed system based on usual software components was able to respond to the medical needs of the local ICU environment. The use of Windows for development allowed us to customize the software to the preexisting organization and contributed to the acceptability of the whole system.

Nanoparticles that reshape the tumor milieu create a therapeutic window for effective T cell therapy in solid malignancies.

PubMed

Zhang, Fan; Stephan, Sirkka B; Ene, Chibawanye I; Smith, Tyrel T; Holland, Eric C; Stephan, Matthias T

2018-05-14

A major obstacle to the success rate of chimeric antigen receptor (CAR-) T cell therapy against solid tumors is the microenvironment antagonistic to T cells that solid tumors create. Conventional checkpoint blockade can silence lymphocyte anti-survival pathways activated by tumors, but because they are systemic, these treatments disrupt immune homeostasis and induce autoimmune side effects. Thus, new technologies are required to remodel the tumor milieu without causing systemic toxicities. Here we demonstrate that targeted nanocarriers that deliver a combination of immune-modulatory agents can remove pro-tumor cell populations and simultaneously stimulate anti-tumor effector cells. We administered repeated infusions of lipid nanoparticles coated with the tumor-targeting peptide iRGD and loaded with a combination of a PI3K inhibitor to inhibit immune-suppressive tumor cells and an alpha-GalCer agonist of therapeutic T cells to synergistically sway the tumor microenvironment of solid tumors from suppressive to stimulatory. This treatment created a therapeutic window of two weeks, enabling tumor-specific CAR-T cells to home to the lesion, undergo robust expansion, and trigger tumor regression. CAR-T cells administered outside this therapeutic window had no curative effect. The lipid nanoparticles we used are easy to manufacture in substantial amounts, and we demonstrate that repeated infusions of them are safe. Our technology may therefore provide a practical and low-cost strategy to potentiate many cancer immunotherapies used to treat solid tumors, including T cell therapy, vaccines, and BITE platforms. Copyright ©2018, American Association for Cancer Research.

The role of proteolytic enzymes in degradation of plant tissues: Summary report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewosz, J.; Kelman, A.; Sequeira, L.

1989-01-01

The proteolytic enzymes produced by Erwinia carotovora subsp. carotovora (Ecc-strain SR 394) grown on various media were examined by isoelectrofocusing in polyacrylamide gels over a pH range of 3-10. In addition to the main protease present in culture filtrates, low concentrations of several other proteases were present in extracts from potato tubers infected by Ecc. Proteases from all these sources were similar and had the following properties: pH optimum near 8.0, calcium dependent, insensitive to serine proteinase and SH-proteinase inhibitors, inhibited by EDTA, and highly thermostable. These enzymes degraded gelatin, soluble collagen and Hide Powder Azure, and showed weak activitymore » on casein, but did not degrade insoluble collagen or elastin.« less

TwinFocus CPV system

NASA Astrophysics Data System (ADS)

Nardello, Marco; Centro, Sandro

2017-09-01

TwinFocus® is a CPV solution that adopts quasi-parabolic, off axis mirrors, to obtain a concentration of 760× on 3J solar cells (Azur space technology) with 44% efficiency. The adoption of this optical solution allows for a cheap, lightweight and space efficient system. In particular, the addition of a secondary optics to the mirror, grants an efficient use of space, with very low thicknesses and a compact modular design. Materials are recyclable and allow for reduction of weights to a minimum level. The product is realized through the cooperation of leading edge industries active in automotive lighting and plastic materials molding. The produced prototypes provide up to 27.6% efficiency according to tests operated on the field with non-optimal spectral conditions.

AP-8 trapped proton environment for solar maximum and solar minimum. [Computer accessible models

NASA Technical Reports Server (NTRS)

Sawyer, D. M.; Vette, J. I.

1976-01-01

Data sets from Ov-3 and Azur indicate a need for improvement in models of the stably trapped proton flux with energies between 0.1 and 400 MeV. Two computer accessible models are described: AP8MAX and AP8MIN. The models are presented in the form of nomographs, B-L plots, R-lambda plots, and equatorial radial profiles. Nomographs of the orbit-integrated fluxes are also discussed. The models are compared with each other, with the data, and with previous AP models. Requirements for future improvements include more complete data coverage and periodic comparisons with new data sets as they become available. The machine-sensible format in which the models are available are described.

Statistical Reproducibility of the Dynamic and Static Fatigue Experiments.

DTIC Science & Technology

1980-10-01

82171a no 3 a s d e te rm-,I n ed7 from t Ynamic ’ra-,4-e 2x oe r imen. Figure 2. T-he c oeffic 4e nt o - v arari an ( C . o f .4eib L’ sIatce --ar a-:e...e rc lecnnique to aeterr-ine zne v~iidit of the assumptions. - .2 Static Fatioue Static -aticue tests entai- , the reDeatec measuremen- c - azure ...ress -ance ncreased, anc- tec.-ease: zs n :El ~ c a -amet: -7 4creas2c. -o r a ze sac, nC~e 3Es3 ra-.<e ~ D 3 s ar, c a s n amD-e , s e : ) rrc uCb c 0

Foldable and Disposable Memory on Paper

PubMed Central

Lee, Byung-Hyun; Lee, Dong-Il; Bae, Hagyoul; Seong, Hyejeong; Jeon, Seung-Bae; Seol, Myung-Lok; Han, Jin-Woo; Meyyappan, M.; Im, Sung-Gap; Choi, Yang-Kyu

2016-01-01

Foldable organic memory on cellulose nanofibril paper with bendable and rollable characteristics is demonstrated by employing initiated chemical vapor deposition (iCVD) for polymerization of the resistive switching layer and inkjet printing of the electrode, where iCVD based on all-dry and room temperature process is very suitable for paper electronics. This memory exhibits a low operation voltage of 1.5 V enabling battery operation compared to previous reports and wide memory window. The memory performance is maintained after folding tests, showing high endurance. Furthermore, the quick and complete disposable nature demonstrated here is attractive for security applications. This work provides an effective platform for green, foldable and disposable electronics based on low cost and versatile materials. PMID:27922094

A JAVA-based multimedia tool for clinical practice guidelines.

PubMed

Maojo, V; Herrero, C; Valenzuela, F; Crespo, J; Lazaro, P; Pazos, A

1997-01-01

We have developed a specific language for the representation of Clinical Practice Guidelines (CPGs) and Windows C++ and platform independent JAVA applications for multimedia presentation and edition of electronically stored CPGs. This approach facilitates translation of guidelines and protocols from paper to computer-based flowchart representations. Users can navigate through the algorithm with a friendly user interface and access related multimedia information within the context of each clinical problem. CPGs can be stored in a computer server and distributed over the World Wide Web, facilitating dissemination, local adaptation, and use as a reference element in medical care. We have chosen the Agency for Health Care and Policy Research's heart failure guideline to demonstrate the capabilities of our tool.

KSC-05PD-0620

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. In the waning twilight, the service structures on Launch Pad 39B (left) and the Mobile Launcher Platform carrying Space Shuttle Discovery glow with lights. The Shuttle began rollout to the pad at 2:04 p.m. EDT from the Vehicle Assembly Building at NASAs Kennedy Space Center, marking a major milestone in the Space Shuttle Programs Return to Flight. Launch of Discovery on its Return to Flight mission, STS-114, is targeted for May 15 with a launch window that extends to June 3. During its 12-day mission, Discoverys seven-person crew will test new hardware and techniques to improve Shuttle safety, as well as deliver supplies to the International Space Station.

[A computer-aided image diagnosis and study system].

PubMed

Li, Zhangyong; Xie, Zhengxiang

2004-08-01

The revolution in information processing, particularly the digitizing of medicine, has changed the medical study, work and management. This paper reports a method to design a system for computer-aided image diagnosis and study. Combined with some good idea of graph-text system and picture archives communicate system (PACS), the system was realized and used for "prescription through computer", "managing images" and "reading images under computer and helping the diagnosis". Also typical examples were constructed in a database and used to teach the beginners. The system was developed by the visual developing tools based on object oriented programming (OOP) and was carried into operation on the Windows 9X platform. The system possesses friendly man-machine interface.

Multi-PON access network using a coarse AWG for smooth migration from TDM to WDM PON

NASA Astrophysics Data System (ADS)

Shachaf, Y.; Chang, C.-H.; Kourtessis, P.; Senior, J. M.

2007-06-01

An interoperable access network architecture based on a coarse array waveguide grating (AWG) is described, displaying dynamic wavelength assignment to manage the network load across multiple PONs. The multi-PON architecture utilizes coarse Gaussian channels of an AWG to facilitate scalability and smooth migration path between TDM and WDM PONs. Network simulations of a cross-operational protocol platform confirmed successful routing of individual PON clusters through 7 nm-wide passband windows of the AWG. Furthermore, polarization-dependent wavelength shift and phase errors of the device proved not to impose restrain on the routing performance. Optical transmission tests at 2.5 Gbit/s for distances up to 20 km are demonstrated.

Multimission image processing and science data visualization

NASA Technical Reports Server (NTRS)

Green, William B.

1993-01-01

The Operational Science Analysis (OSA) Functional area supports science instrument data display, analysis, visualization and photo processing in support of flight operations of planetary spacecraft managed by the Jet Propulsion Laboratory (JPL). This paper describes the data products generated by the OSA functional area, and the current computer system used to generate these data products. The objectives on a system upgrade now in process are described. The design approach to development of the new system are reviewed, including use of the Unix operating system and X-Window display standards to provide platform independence, portability, and modularity within the new system, is reviewed. The new system should provide a modular and scaleable capability supporting a variety of future missions at JPL.

A VxD-based automatic blending system using multithreaded programming.

PubMed

Wang, L; Jiang, X; Chen, Y; Tan, K C

2004-01-01

This paper discusses the object-oriented software design for an automatic blending system. By combining the advantages of a programmable logic controller (PLC) and an industrial control PC (ICPC), an automatic blending control system is developed for a chemical plant. The system structure and multithread-based communication approach are first presented in this paper. The overall software design issues, such as system requirements and functionalities, are then discussed in detail. Furthermore, by replacing the conventional dynamic link library (DLL) with virtual X device drivers (VxD's), a practical and cost-effective solution is provided to improve the robustness of the Windows platform-based automatic blending system in small- and medium-sized plants.

WOGEN. Work Order Generation Macros for Word Perfect 6.X for Windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grenz, G.

Included are three general WP macros (two independent and one multiple) and a template used at the Test Reactor Area (TRA) for the generation of the Work Orders (WO`s) used to perform corrective and preventative maintenance, as well as modifications of existing systems and installation of new systems. They incorporate facility specific requirements as well as selected federal/state orders. These macros are used to generate a WP document which is then converted into ASCII text for import to the maintenance software. Currently we are using MCRS but should be compatible with other platforms such as Passport. Reference the included filemore » Wogen.txt for installation and usage instructions.« less

Work Order Generation Macros for Word Perfect 6.X for Windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grenz, Gordon G.

Included are three general WP macros (two independent and one multiple) and a template used at the Test Reactor Area (TRA) for the generation of the Work Orders (WO's) used to perform corrective and preventative maintenance, as well as modifications of existing systems and installation of new systems. They incorporate facility specific requirements as well as selected federal/state orders. These macros are used to generate a WP document which is then converted into ASCII text for import to the maintenance software. Currently we are using MCRS but should be compatible with other platforms such as Passport. Reference the included filemore » Wogen.txt for installation and usage instructions.« less

Viewpoints: A New Computer Program for Interactive Exploration of Large Multivariate Space Science and Astrophysics Data.

NASA Astrophysics Data System (ADS)

Levit, Creon; Gazis, P.

2006-06-01

The graphics processing units (GPUs) built in to all professional desktop and laptop computers currently on the market are capable of transforming, filtering, and rendering hundreds of millions of points per second. We present a prototype open-source cross-platform (windows, linux, Apple OSX) application which leverages some of the power latent in the GPU to enable smooth interactive exploration and analysis of large high-dimensional data using a variety of classical and recent techniques. The targeted application area is the interactive analysis of complex, multivariate space science and astrophysics data sets, with dimensionalities that may surpass 100 and sample sizes that may exceed 10^6-10^8.

CheD: chemical database compilation tool, Internet server, and client for SQL servers.

PubMed

Trepalin, S V; Yarkov, A V

2001-01-01

An efficient program, which runs on a personal computer, for the storage, retrieval, and processing of chemical information, is presented, The program can work both as a stand-alone application or in conjunction with a specifically written Web server application or with some standard SQL servers, e.g., Oracle, Interbase, and MS SQL. New types of data fields are introduced, e.g., arrays for spectral information storage, HTML and database links, and user-defined functions. CheD has an open architecture; thus, custom data types, controls, and services may be added. A WWW server application for chemical data retrieval features an easy and user-friendly installation on Windows NT or 95 platforms.

Free and open source software for the manipulation of digital images.

PubMed

Solomon, Robert W

2009-06-01

Free and open source software is a type of software that is nearly as powerful as commercial software but is freely downloadable. This software can do almost everything that the expensive programs can. GIMP (gnu image manipulation program) is the free program that is comparable to Photoshop, and versions are available for Windows, Macintosh, and Linux platforms. This article briefly describes how GIMP can be installed and used to manipulate radiology images. It is no longer necessary to budget large amounts of money for high-quality software to achieve the goals of image processing and document creation because free and open source software is available for the user to download at will.

XAFSmass: a program for calculating the optimal mass of XAFS samples

NASA Astrophysics Data System (ADS)

Klementiev, K.; Chernikov, R.

2016-05-01

We present a new implementation of the XAFSmass program that calculates the optimal mass of XAFS samples. It has several improvements as compared to the old Windows based program XAFSmass: 1) it is truly platform independent, as provided by Python language, 2) it has an improved parser of chemical formulas that enables parentheses and nested inclusion-to-matrix weight percentages. The program calculates the absorption edge height given the total optical thickness, operates with differently determined sample amounts (mass, pressure, density or sample area) depending on the aggregate state of the sample and solves the inverse problem of finding the elemental composition given the experimental absorption edge jump and the chemical formula.

Interactive mission planning for a Space Shuttle flight experiment - A case history

NASA Technical Reports Server (NTRS)

Harris, H. M.

1986-01-01

Scientific experiments which use the Space Shuttle as a platform require the development of new operations techniques for the command and control of the instrument. Principal among these is the ability to simulate the complex maneuvers of the orbiter's path realistically. Computer generated graphics provide a window into the actual and predicted performance of the instrument and allow sophisticated control of the instrument under varying conditions. In October of 1984 the Shuttle carried a synthetic aperture radar built by JPL for the purpose of recording images of the earth surface. The mission deviated from planned operation in almost every conceivable way and provided an exacting test bed for concepts of interactive mission planning.

oneChannelGUI: a graphical interface to Bioconductor tools, designed for life scientists who are not familiar with R language.

PubMed

Sanges, Remo; Cordero, Francesca; Calogero, Raffaele A

2007-12-15

OneChannelGUI is an add-on Bioconductor package providing a new set of functions extending the capability of the affylmGUI package. This library provides a graphical interface (GUI) for Bioconductor libraries to be used for quality control, normalization, filtering, statistical validation and data mining for single channel microarrays. Affymetrix 3' expression (IVT) arrays as well as the new whole transcript expression arrays, i.e. gene/exon 1.0 ST, are actually implemented. oneChannelGUI is available for most platforms on which R runs, i.e. Windows and Unix-like machines. http://www.bioconductor.org/packages/2.0/bioc/html/oneChannelGUI.html

Computer virus information update CIAC-2301

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orvis, W.J.

1994-01-15

While CIAC periodically issues bulletins about specific computer viruses, these bulletins do not cover all the computer viruses that affect desktop computers. The purpose of this document is to identify most of the known viruses for the MS-DOS and Macintosh platforms and give an overview of the effects of each virus. The authors also include information on some windows, Atari, and Amiga viruses. This document is revised periodically as new virus information becomes available. This document replaces all earlier versions of the CIAC Computer virus Information Update. The date on the front cover indicates date on which the information inmore » this document was extracted from CIAC`s Virus database.« less

GRIL: genome rearrangement and inversion locator.

PubMed

Darling, Aaron E; Mau, Bob; Blattner, Frederick R; Perna, Nicole T

2004-01-01

GRIL is a tool to automatically identify collinear regions in a set of bacterial-size genome sequences. GRIL uses three basic steps. First, regions of high sequence identity are located. Second, some of these regions are filtered based on user-specified criteria. Finally, the remaining regions of sequence identity are used to define significant collinear regions among the sequences. By locating collinear regions of sequence, GRIL provides a basis for multiple genome alignment using current alignment systems. GRIL also provides a basis for using current inversion distance tools to infer phylogeny. GRIL is implemented in C++ and runs on any x86-based Linux or Windows platform. It is available from http://asap.ahabs.wisc.edu/gril

The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology.

PubMed

Blakes, Jonathan; Twycross, Jamie; Romero-Campero, Francisco Jose; Krasnogor, Natalio

2011-12-01

The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments and reactions. Models are simulated either using stochastic simulation or numerical integration, and visualized in time and space. Model parameters and structure can be optimized with evolutionary algorithms, and model properties calculated using probabilistic model checking. Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3. Natalio.Krasnogor@nottingham.ac.uk.

gkmSVM: an R package for gapped-kmer SVM

PubMed Central

Ghandi, Mahmoud; Mohammad-Noori, Morteza; Ghareghani, Narges; Lee, Dongwon; Garraway, Levi; Beer, Michael A.

2016-01-01

Summary: We present a new R package for training gapped-kmer SVM classifiers for DNA and protein sequences. We describe an improved algorithm for kernel matrix calculation that speeds run time by about 2 to 5-fold over our original gkmSVM algorithm. This package supports several sequence kernels, including: gkmSVM, kmer-SVM, mismatch kernel and wildcard kernel. Availability and Implementation: gkmSVM package is freely available through the Comprehensive R Archive Network (CRAN), for Linux, Mac OS and Windows platforms. The C ++ implementation is available at www.beerlab.org/gkmsvm Contact: mghandi@gmail.com or mbeer@jhu.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27153639

Electro-optic guided-mode resonance tuning suppressible by optically induced screening in a vertically coupled hybrid GaN/Si microring resonator

NASA Astrophysics Data System (ADS)

Thubthimthong, B.; Sasaki, T.; Hane, K.

2018-02-01

GaN as a nanophotonic material has gained much attention in recent years. Using the hybrid GaN/Si platform, we report the electro-optic tuning of guided-mode resonance in a vertically coupled hybrid GaN/Si microring resonator operating in the 1.5 μm window with up to a 6 dB extinction ratio and a 1.5 MHz modulation frequency (test equipment limit). The electro-optic tuning could be optically suppressed by electron-hole-originated screening induced by an ultraviolet excitation at 325 nm. Our work may benefit in externally intervenable optical interconnects for uninterrupted secure photonic networks.

LSBB: a Low Noise Laboratory for Inter--Disciplinary Underground Science and Technology in Rustrel--Pays d'Apt, Vaucluse, France

NASA Astrophysics Data System (ADS)

Gaffet, S.

2008-12-01

Located in the Provence-Alpes--Côte d'Azur region (Southern France), LSBB is an underground facility that is dedicated since 10 years ago, to interdisciplinary fundamental and applied R&D activities in a low level anthropogenic area that secures the site with one of the lowest environmental noise in the world. LSBB is both a host-laboratory for private and academic experiments and a unique access-laboratory to study near- surface multi-physics environmental processes. This site offers operational facilities characterized by a fully connected fiber-optics network managed by a team of 3 permanent engineers and the collaboration with more than 30 research units in Europe. Initially designed for the French nuclear defence and converted in 1997 into an academic laboratory, LSBB is a hardened facility made of 3.7~km of horizontal galleries and vaults buried 500~m deep within the unsaturated zone of a carbonate platform which is a typical analogue of the currently exploited water and oil reservoirs of the Middle--East. Another major attraction of the LSBB is that it hosts a unique--in--the--world broad low-pass filter magnetic shielded zone (1500~m3 with electromagnetic noise level below 2~fT/√Hz for frequencies above 50~Hz). Thanks to such an exceptional environmental and technological context, LSBB provides one of the best european opportunities for the development of research projects related to near-surface imaging and multiscale and multiphysics coupled processes in natural porous media; magnetic field perturbations coupled to seismic wave excitations; thermo--hydromechanical and chemical fluid--rock interaction in heterogeneous carbonates; dark matter research; reliability and sensitivity to the natural radioactive environment of nano-- electronic and nano--structures. Projects interact through co--sharing of the multi--parametric and at--the-- leading--edge measurements and results, that are centralised in a dedicated internet plateform.

Histostitcher™: An informatics software platform for reconstructing whole-mount prostate histology using the extensible imaging platform framework

PubMed Central

Toth, Robert J.; Shih, Natalie; Tomaszewski, John E.; Feldman, Michael D.; Kutter, Oliver; Yu, Daphne N.; Paulus, John C.; Paladini, Ginaluca; Madabhushi, Anant

2014-01-01

Context: Co-registration of ex-vivo histologic images with pre-operative imaging (e.g., magnetic resonance imaging [MRI]) can be used to align and map disease extent, and to identify quantitative imaging signatures. However, ex-vivo histology images are frequently sectioned into quarters prior to imaging. Aims: This work presents Histostitcher™, a software system designed to create a pseudo whole mount histology section (WMHS) from a stitching of four individual histology quadrant images. Materials and Methods: Histostitcher™ uses user-identified fiducials on the boundary of two quadrants to stitch such quadrants. An original prototype of Histostitcher™ was designed using the Matlab programming languages. However, clinical use was limited due to slow performance, computer memory constraints and an inefficient workflow. The latest version was created using the extensible imaging platform (XIP™) architecture in the C++ programming language. A fast, graphics processor unit renderer was designed to intelligently cache the visible parts of the histology quadrants and the workflow was significantly improved to allow modifying existing fiducials, fast transformations of the quadrants and saving/loading sessions. Results: The new stitching platform yielded significantly more efficient workflow and reconstruction than the previous prototype. It was tested on a traditional desktop computer, a Windows 8 Surface Pro table device and a 27 inch multi-touch display, with little performance difference between the different devices. Conclusions: Histostitcher™ is a fast, efficient framework for reconstructing pseudo WMHS from individually imaged quadrants. The highly modular XIP™ framework was used to develop an intuitive interface and future work will entail mapping the disease extent from the pseudo WMHS onto pre-operative MRI. PMID:24843820

Flexible Software Architecture for Visualization and Seismic Data Analysis

NASA Astrophysics Data System (ADS)

Petunin, S.; Pavlov, I.; Mogilenskikh, D.; Podzyuban, D.; Arkhipov, A.; Baturuin, N.; Lisin, A.; Smith, A.; Rivers, W.; Harben, P.

2007-12-01

Research in the field of seismology requires software and signal processing utilities for seismogram manipulation and analysis. Seismologists and data analysts often encounter a major problem in the use of any particular software application specific to seismic data analysis: the tuning of commands and windows to the specific waveforms and hot key combinations so as to fit their familiar informational environment. The ability to modify the user's interface independently from the developer requires an adaptive code structure. An adaptive code structure also allows for expansion of software capabilities such as new signal processing modules and implementation of more efficient algorithms. Our approach is to use a flexible "open" architecture for development of geophysical software. This report presents an integrated solution for organizing a logical software architecture based on the Unix version of the Geotool software implemented on the Microsoft NET 2.0 platform. Selection of this platform greatly expands the variety and number of computers that can implement the software, including laptops that can be utilized in field conditions. It also facilitates implementation of communication functions for seismic data requests from remote databases through the Internet. The main principle of the new architecture for Geotool is that scientists should be able to add new routines for digital waveform analysis via software plug-ins that utilize the basic Geotool display for GUI interaction. The use of plug-ins allows the efficient integration of diverse signal-processing software, including software still in preliminary development, into an organized platform without changing the fundamental structure of that platform itself. An analyst's use of Geotool is tracked via a metadata file so that future studies can reconstruct, and alter, the original signal processing operations. The work has been completed in the framework of a joint Russian- American project.

Driving platform for OLED lighting investigations

NASA Astrophysics Data System (ADS)

Vogel, Uwe; Elgner, Andreas; Kreye, Daniel; Amelung, Jörg; Scholles, Michael

2006-08-01

OLED technology may be excellently suitable for lighting applications by combining high efficiency, cost effective manufacturing and the use of low cost materials. Certain issues remain to be solved so far, including OLED brightness, color, lifetime, large area uniformity and encapsulation. Another aspect, that might be capable in addressing some of the mentioned issues, is OLED lighting electrical driving. We report on the design of a driving platform for OLED lighting test panels or substrates. It is intended for being a test environment for lighting substrates as well as demonstration/presentation environment. It is based on a 128-channel passive-matrix driver/controller ASIC OC2. Its key component is an MSP430-compatible 16-bit micro-controller core including embedded Flash memory (program), EEPROM (parameter), and RAM (data memory). A significant feature of the device is an electronic approach for improving the lifetime/uniformity behavior of connected OLED. The embedded micro-controller is the key to the high versatility of OC2, since by firmware modification it can be adapted to various applications and conditions. Here its application for an OLED lighting driving platform is presented. Major features of this platform are PC-control mode (via USB interface), stand-alone mode (no external control necessary, just power supply), on-board OLED panel parameter storage, flat geometry of OLED lighting panel carrier (board), AC and DC driving regimes, adjustable reverse voltage, dedicated user SW (PC/Windows-based), sub-tile patterning and single sub-tile control, combination of multiple channels for increasing driving current. This publication contains results of the project "High Brightness OLEDs for ICT & Next Generation Lighting Applications" (OLLA), funded by the European Commission.

X-Windows PVT Widget Class

NASA Technical Reports Server (NTRS)

Barry, Matthew R.

2006-01-01

The X-Windows Process Validation Table (PVT) Widget Class ( Class is used here in the object-oriented-programming sense of the word) was devised to simplify the task of implementing network registration services for Information Sharing Protocol (ISP) graphical-user-interface (GUI) computer programs. Heretofore, ISP PVT programming tasks have required many method calls to identify, query, and interpret the connections and messages exchanged between a client and a PVT server. Normally, programmers have utilized direct access to UNIX socket libraries to implement the PVT protocol queries, necessitating the use of many lines of source code to perform frequent tasks. Now, the X-Windows PVT Widget Class encapsulates ISP client server network registration management tasks within the framework of an X Windows widget. Use of the widget framework enables an X Windows GUI program to interact with PVT services in an abstract way and in the same manner as that of other graphical widgets, making it easier to program PVT clients. Wrapping the PVT services inside the widget framework enables a programmer to treat a PVT server interface as though it were a GUI. Moreover, an alternate subclass could implement another service in a widget of the same type. This program was written by Matthew R. Barry of United Space Alliance for Johnson Space Center. For further information, contact the Johnson Technology Transfer Office at (281) 483-3809. MSC-23582 Shuttle Data Center File- Processing Tool in Java A Java-language computer program has been written to facilitate mining of data in files in the Shuttle Data Center (SDC) archives. This program can be executed on a variety of workstations or via Web-browser programs. This program is partly similar to prior C-language programs used for the same purpose, while differing from those programs in that it exploits the platform-neutrality of Java in implementing several features that are important for analysis of large sets of time-series data. The program supports regular expression queries of SDC archive files, reads the files, interleaves the time-stamped samples according to a chosen output, then transforms the results into that format. A user can choose among a variety of output file formats that are useful for diverse purposes, including plotting, Markov modeling, multivariate density estimation, and wavelet multiresolution analysis, as well as for playback of data in support of simulation and testing.

Parallelization of Rocket Engine Simulator Software (PRESS)

NASA Technical Reports Server (NTRS)

Cezzar, Ruknet

1998-01-01

We have outlined our work in the last half of the funding period. We have shown how a demo package for RESSAP using MPI can be done. However, we also mentioned the difficulties with the UNIX platform. We have reiterated some of the suggestions made during the presentation of the progress of the at Fourth Annual HBCU Conference. Although we have discussed, in some detail, how TURBDES/PUMPDES software can be run in parallel using MPI, at present, we are unable to experiment any further with either MPI or PVM. Due to X windows not being implemented, we are also not able to experiment further with XPVM, which it will be recalled, has a nice GUI interface. There are also some concerns, on our part, about MPI being an appropriate tool. The best thing about MPr is that it is public domain. Although and plenty of documentation exists for the intricacies of using MPI, little information is available on its actual implementations. Other than very typical, somewhat contrived examples, such as Jacobi algorithm for solving Laplace's equation, there are few examples which can readily be applied to real situations, such as in our case. In effect, the review of literature on both MPI and PVM, and there is a lot, indicate something similar to the enormous effort which was spent on LISP and LISP-like languages as tools for artificial intelligence research. During the development of a book on programming languages [12], when we searched the literature for very simple examples like taking averages, reading and writing records, multiplying matrices, etc., we could hardly find a any! Yet, so much was said and done on that topic in academic circles. It appears that we faced the same problem with MPI, where despite significant documentation, we could not find even a simple example which supports course-grain parallelism involving only a few processes. From the foregoing, it appears that a new direction may be required for more productive research during the extension period (10/19/98 - 10/18/99). At the least, the research would need to be done on Windows 95/Windows NT based platforms. Moreover, with the acquisition of Lahey Fortran package for PC platform, and the existing Borland C + + 5. 0, we can do work on C + + wrapper issues. We have carefully studied the blueprint for Space Transportation Propulsion Integrated Design Environment for the next 25 years [13] and found the inclusion of HBCUs in that effort encouraging. Especially in the long period for which a map is provided, there is no doubt that HBCUs will grow and become better equipped to do meaningful research. In the shorter period, as was suggested in our presentation at the HBCU conference, some key decisions regarding the aging Fortran based software for rocket propellants will need to be made. One important issue is whether or not object oriented languages such as C + + or Java should be used for distributed computing. Whether or not "distributed computing" is necessary for the existing software is yet another, larger, question to be tackled with.

NASA's MODIS/VIIRS Land Surface Temperature and Emissivity Products: Asssessment of Accuracy, Continuity and Science Uses

NASA Astrophysics Data System (ADS)

Hulley, G. C.; Malakar, N.; Islam, T.

2017-12-01

Land Surface Temperature and Emissivity (LST&E) are an important Earth System Data Record (ESDR) and Environmental Climate Variable (ECV) defined by NASA and GCOS respectively. LST&E data are key variables used in land cover/land use change studies, in surface energy balance and atmospheric water vapor retrieval models and retrievals, and in climate research. LST&E products are currently produced on a routine basis using data from the MODIS instruments on the NASA EOS platforms and by the VIIRS instrument on the Suomi-NPP platform that serves as a bridge between NASA EOS and the next-generation JPSS platforms. Two new NASA LST&E products for MODIS (MxD21) and VIIRS (VNP21) are being produced during 2017 using a new approach that addresses discrepancies in accuracy and consistency between the current suite of split-window based LST products. The new approach uses a Temperature Emissivity Separation (TES) algorithm, originally developed for the ASTER instrument, to physically retrieve both LST and spectral emissivity consistently for both sensors with high accuracy and well defined uncertainties. This study provides a rigorous assessment of accuracy of the MxD21/VNP21 products using temperature- and radiance-based validation strategies and demonstrates continuity between the products using collocated matchups over CONUS. We will further demonstrate potential science use of the new products with studies related to heat waves, monitoring snow melt dynamics, and land cover/land use change.

Nanoelectronics enabled chronic multimodal neural platform in a mouse ischemic model.

PubMed

Luan, Lan; Sullender, Colin T; Li, Xue; Zhao, Zhengtuo; Zhu, Hanlin; Wei, Xiaoling; Xie, Chong; Dunn, Andrew K

2018-02-01

Despite significant advancements of optical imaging techniques for mapping hemodynamics in small animal models, it remains challenging to combine imaging with spatially resolved electrical recording of individual neurons especially for longitudinal studies. This is largely due to the strong invasiveness to the living brain from the penetrating electrodes and their limited compatibility with longitudinal imaging. We implant arrays of ultraflexible nanoelectronic threads (NETs) in mice for neural recording both at the brain surface and intracortically, which maintain great tissue compatibility chronically. By mounting a cranial window atop of the NET arrays that allows for chronic optical access, we establish a multimodal platform that combines spatially resolved electrical recording of neural activity and laser speckle contrast imaging (LSCI) of cerebral blood flow (CBF) for longitudinal studies. We induce peri-infarct depolarizations (PIDs) by targeted photothrombosis, and show the ability to detect its occurrence and propagation through spatiotemporal variations in both extracellular potentials and CBF. We also demonstrate chronic tracking of single-unit neural activity and CBF over days after photothrombosis, from which we observe reperfusion and increased firing rates. This multimodal platform enables simultaneous mapping of neural activity and hemodynamic parameters at the microscale for quantitative, longitudinal comparisons with minimal perturbation to the baseline neurophysiology. The ability to spatiotemporally resolve and chronically track CBF and neural electrical activity in the same living brain region has broad applications for studying the interplay between neural and hemodynamic responses in health and in cerebrovascular and neurological pathologies. Copyright © 2017 Elsevier B.V. All rights reserved.

STEREO: a program on a PC-Windows 95 platform for recording and evaluating quantitative stereologic investigations of multistage hepatocarcinogenesis in rodents.

PubMed

Xu, Y H; Dragan, Y P; Campbell, H A; Pitot, H C

1998-04-01

The most common organ site of neoplasms induced by carcinogenic chemicals in the rodent bioassay is the liver. The development of cancer in rodent liver is a multistage process involving sequentially the stages of initiation, promotion, and progression. During the stages of promotion and progression, numerous lesions termed altered hepatic foci (AHF) develop. STEREO was developed for the purpose of efficient and accurate quantitation of AHF and related lesions in experimental and test rodents. The system utilized is equipped with a microcomputer (IBM-compatible PC running Windows 95) and a Summagraphics MICROGRID or SummaSketch tablet digitizer. The program records information from digitization of single or serial sections obtained randomly from rat liver tissue. With this information and the methods of quantitative stereology, both the number and volume percentage fraction of AHF in liver are calculated in three dimensions. The recorded data files can be printed graphically or in the format of tabular numerical data. The results of stereologic calculations are stored on floppy disks and can be sorted into different categories and analyzed or displayed with the use of statistics and graphic functions built into the overall program. Results may also be exported into Microsoft Excel for use at a later time. Any IBM-compatible PC capable of utilizing Windows 95 and MS Office can be used with STEREO, which offers inexpensive, easily operated software to obtain three-dimensional information from sections of two dimensions for the identification and relative potency of initiators, promoters, and progressors, and for the establishment of information potentially useful in developing estimations of risk for human cancer.

Seismic Window Selection and Misfit Measurements for Global Adjoint Tomography

NASA Astrophysics Data System (ADS)

Lei, W.; Bozdag, E.; Lefebvre, M.; Podhorszki, N.; Smith, J. A.; Tromp, J.

2013-12-01

Global Adjoint Tomography requires fast parallel processing of large datasets. After obtaing the preprocessed observed and synthetic seismograms, we use the open source software packages FLEXWIN (Maggi et al. 2007) to select time windows and MEASURE_ADJ to make measurements. These measurements define adjoint sources for data assimilation. Previous versions of these tools work on a pair of SAC files---observed and synthetic seismic data for the same component and station, and loop over all seismic records associated with one earthquake. Given the large number of stations and earthquakes, the frequent read and write operations create severe I/O bottlenecks on modern computing platforms. We present new versions of these tools utilizing a new seismic data format, namely the Adaptive Seismic Data Format(ASDF). This new format shows superior scalability for applications on high-performance computers and accommodates various types of data, including earthquake, industry and seismic interferometry datasets. ASDF also provides user-friendly APIs, which can be easily integrated into the adjoint tomography workflow and combined with other data processing tools. In addition to solving the I/O bottleneck, we are making several improvements to these tools. For example, FLEXWIN is tuned to select windows for different types of earthquakes. To capture their distinct features, we categorize earthquakes by their depths and frequency bands. Moreover, instead of only picking phases between the first P arrival and the surface-wave arrivals, our aim is to select and assimilate many other later prominent phases in adjoint tomography. For example, in the body-wave band (17 s - 60 s), we include SKS, sSKS and their multiple, while in the surface-wave band (60 s - 120 s) we incorporate major-arc surface waves.

SigHunt: horizontal gene transfer finder optimized for eukaryotic genomes.

PubMed

Jaron, Kamil S; Moravec, Jiří C; Martínková, Natália

2014-04-15

Genomic islands (GIs) are DNA fragments incorporated into a genome through horizontal gene transfer (also called lateral gene transfer), often with functions novel for a given organism. While methods for their detection are well researched in prokaryotes, the complexity of eukaryotic genomes makes direct utilization of these methods unreliable, and so labour-intensive phylogenetic searches are used instead. We present a surrogate method that investigates nucleotide base composition of the DNA sequence in a eukaryotic genome and identifies putative GIs. We calculate a genomic signature as a vector of tetranucleotide (4-mer) frequencies using a sliding window approach. Extending the neighbourhood of the sliding window, we establish a local kernel density estimate of the 4-mer frequency. We score the number of 4-mer frequencies in the sliding window that deviate from the credibility interval of their local genomic density using a newly developed discrete interval accumulative score (DIAS). To further improve the effectiveness of DIAS, we select informative 4-mers in a range of organisms using the tetranucleotide quality score developed herein. We show that the SigHunt method is computationally efficient and able to detect GIs in eukaryotic genomes that represent non-ameliorated integration. Thus, it is suited to scanning for change in organisms with different DNA composition. Source code and scripts freely available for download at http://www.iba.muni.cz/index-en.php?pg=research-data-analysis-tools-sighunt are implemented in C and R and are platform-independent. 376090@mail.muni.cz or martinkova@ivb.cz. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Minimizing scatter-losses during pre-heat for magneto-inertial fusion targets

NASA Astrophysics Data System (ADS)

Geissel, Matthias; Harvey-Thompson, Adam J.; Awe, Thomas J.; Bliss, David E.; Glinsky, Michael E.; Gomez, Matthew R.; Harding, Eric; Hansen, Stephanie B.; Jennings, Christopher; Kimmel, Mark W.; Knapp, Patrick; Lewis, Sean M.; Peterson, Kyle; Schollmeier, Marius; Schwarz, Jens; Shores, Jonathon E.; Slutz, Stephen A.; Sinars, Daniel B.; Smith, Ian C.; Speas, C. Shane; Vesey, Roger A.; Weis, Matthew R.; Porter, John L.

2018-02-01

The size, temporal and spatial shape, and energy content of a laser pulse for the pre-heat phase of magneto-inertial fusion affect the ability to penetrate the window of the laser-entrance-hole and to heat the fuel behind it. High laser intensities and dense targets are subject to laser-plasma-instabilities (LPI), which can lead to an effective loss of pre-heat energy or to pronounced heating of areas that should stay unexposed. While this problem has been the subject of many studies over the last decades, the investigated parameters were typically geared towards traditional laser driven Inertial Confinement Fusion (ICF) with densities either at 10% and above or at 1% and below the laser's critical density, electron temperatures of 3-5 keV, and laser powers near (or in excess of) 1 × 1015 W/cm2. In contrast, Magnetized Liner Inertial Fusion (MagLIF) [Slutz et al., Phys. Plasmas 17, 056303 (2010) and Slutz and Vesey, Phys. Rev. Lett. 108, 025003 (2012)] currently operates at 5% of the laser's critical density using much thicker windows (1.5-3.5 μm) than the sub-micron thick windows of traditional ICF hohlraum targets. This article describes the Pecos target area at Sandia National Laboratories using the Z-Beamlet Laser Facility [Rambo et al., Appl. Opt. 44(12), 2421 (2005)] as a platform to study laser induced pre-heat for magneto-inertial fusion targets, and the related progress for Sandia's MagLIF program. Forward and backward scattered light were measured and minimized at larger spatial scales with lower densities, temperatures, and powers compared to LPI studies available in literature.

Visual PEF Reader - VIPER

NASA Technical Reports Server (NTRS)

Luo, Victor; Khanampornpan, Teerapat; Boehmer, Rudy A.; Kim, Rachel Y.

2011-01-01

This software graphically displays all pertinent information from a Predicted Events File (PEF) using the Java Swing framework, which allows for multi-platform support. The PEF is hard to weed through when looking for specific information and it is a desire for the MRO (Mars Reconn aissance Orbiter) Mission Planning & Sequencing Team (MPST) to have a different way to visualize the data. This tool will provide the team with a visual way of reviewing and error-checking the sequence product. The front end of the tool contains much of the aesthetically appealing material for viewing. The time stamp is displayed in the top left corner, and highlighted details are displayed in the bottom left corner. The time bar stretches along the top of the window, and the rest of the space is allotted for blocks and step functions. A preferences window is used to control the layout of the sections along with the ability to choose color and size of the blocks. Double-clicking on a block will show information contained within the block. Zooming into a certain level will graphically display that information as an overlay on the block itself. Other functions include using hotkeys to navigate, an option to jump to a specific time, enabling a vertical line, and double-clicking to zoom in/out. The back end involves a configuration file that allows a more experienced user to pre-define the structure of a block, a single event, or a step function. The individual will have to determine what information is important within each block and what actually defines the beginning and end of a block. This gives the user much more flexibility in terms of what the tool is searching for. In addition to the configurability, all the settings in the preferences window are saved in the configuration file as well

The Microscope Mission and Pre-Flight Performance Verification

NASA Astrophysics Data System (ADS)

Hudson, D.; Touboul, P.; Rodrigues, M.

2006-04-01

Recent developments in fundamental physics have renewed interest in disproving the equivalence principle. The MICROSCOPE mission will be the first test to capitalize on the advantages of space to achieve an accuracy of 10-15, more than two orders of magnitude better than current ground based results. It is a joint CNES, ONERA, and Observatoire de la Côte d'Azur mission in the CNES Myriade microsatellite program. The principle of the test is to place two masses of different material on precisely the same orbit and measure any difference in the forces required to maintain the common orbit. The test is performed by a differential electrostatic accelerometer containing two concentric cylindrical test masses. This paper will present both an overview of the mission, and a description of the accelerometer development and performance verification.

SED16 autonomous star tracker night sky testing

NASA Astrophysics Data System (ADS)

Foisneau, Thierry; Piriou, Véronique; Perrimon, Nicolas; Jacob, Philippe; Blarre, Ludovic; Vilaire, Didier

2017-11-01

The SED16 is an autonomous multi-missions star tracker which delivers three axis satellite attitude in an inertial reference frame and the satellite angular velocity with no prior information. The qualification process of this star sensor includes five validation steps using optical star simulator, digitized image simulator and a night sky tests setup. The night sky testing was the final step of the qualification process during which all the functions of the star tracker were used in almost nominal conditions : Autonomous Acquisition of the attitude, Autonomous Tracking of ten stars. These tests were performed in Calern in the premises of the OCA (Observatoire de la Cote d'Azur). The test set-up and the test results are described after a brief review of the sensor main characteristics and qualification process.

Speckle interferometry with PISCO in Merate and prospects for the future

NASA Astrophysics Data System (ADS)

Scardia, M.; Prieur, J. L.; Argyle, R. W.; Pansecchi, L.; Gili, R.; Koechlin, L.

2012-05-01

Speckle interferometry measurements of binary stars have been regularly obtained with PISCO at the 1-meter Zeiss telescope of the I.N.A.F. - Osservatorio Astronomico di Brera (Merate, Italy) since the end of 2003. We present here some recent results and some projects for extending and improving the scientific reach of our program. In particular, we plan to acquire more efficient detectors and install PISCO on a computer-controlled telescope in a better site belonging to Observatoire de la Côte d'Azur (OCA, Caussols, France). In the future, we would like to be able to operate remotely PISCO, its detector and the telescope. Finally we present PISCO2, the new speckle camera of our group that has been built for the OCA 76-cm refractor.)

Low frequency ultrasonic-assisted hydrolysis of starch in the presence of α-amylase.

PubMed

Gaquere-Parker, Anne; Taylor, Tamera; Hutson, Raihannah; Rizzo, Ashley; Folds, Aubrey; Crittenden, Shastina; Zahoor, Neelam; Hussein, Bilal; Arruda, Aaron

2018-03-01

Hydrolysis of starch is an important process in the food industry and in the production of bioethanol or smaller carbohydrate molecules that can be used as starting blocks for chemical synthesis. Such hydrolysis can be enhanced by lowering the pH, heating the reaction mixture or catalyzing the reaction with enzymes. This study reports the effect of sonication on the reaction rate of starch hydrolysis at different temperatures, in the presence or absence of alpha-amylase. Starch Azure, a commercially available potato starch covalently linked with Remazol Brilliant Blue, has been chosen since its hydrolysis releases a blue dye, which concentration can be monitored by UV Vis spectroscopy. Ultrasounds, regardless of experimental conditions, provide the highest reaction rate for such hydrolysis. Copyright © 2017 Elsevier B.V. All rights reserved.

Flame Detector

NASA Technical Reports Server (NTRS)

1990-01-01

Scientific Instruments, Inc. has now developed a second generation, commercially available instrument to detect flames in hazardous environments, typically refineries, chemical plants and offshore drilling platforms. The Model 74000 detector incorporates a sensing circuit that detects UV radiation in a 100 degree conical field of view extending as far as 250 feet from the instrument. It operates in a bandwidth that makes it virtually 'blind' to solar radiation while affording extremely high sensitivity to ultraviolet flame detection. A 'windowing' technique accurately discriminates between background UV radiation and ultraviolet emitted from an actual flame, hence the user is assured of no false alarms. Model 7410CP is a combination controller and annunciator panel designed to monitor and control as many as 24 flame detectors. *Model 74000 is no longer being manufactured.

KSC-05PD-0633

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. Space Shuttle Discovery lingers at the foot of Launch Pad 39B in the evening twilight. First motion from the Vehicle Assembly Building was at 2:04 p.m. EDT April 6, and the Shuttle was hard down on the pad at 1:16 a.m. EDT April 7. The Shuttle sits atop a Mobile Launcher Platform transported by a Crawler-Transporter underneath. Launch of Discovery on its Return to Flight mission, STS-114, is targeted for May 15 with a launch window that extends to June 3. During its 12-day mission, Discoverys seven-member crew will test new hardware and techniques to improve Shuttle safety, as well as deliver supplies to the International Space Station. Photo courtesy of Scott Andrews.

Application of resist-profile-aware source optimization in 28 nm full chip optical proximity correction

NASA Astrophysics Data System (ADS)

Zhu, Jun; Zhang, David Wei; Kuo, Chinte; Wang, Qing; Wei, Fang; Zhang, Chenming; Chen, Han; He, Daquan; Hsu, Stephen D.

2017-07-01

As technology node shrinks, aggressive design rules for contact and other back end of line (BEOL) layers continue to drive the need for more effective full chip patterning optimization. Resist top loss is one of the major challenges for 28 nm and below technology nodes, which can lead to post-etch hotspots that are difficult to predict and eventually degrade the process window significantly. To tackle this problem, we used an advanced programmable illuminator (FlexRay) and Tachyon SMO (Source Mask Optimization) platform to make resistaware source optimization possible, and it is proved to greatly improve the imaging contrast, enhance focus and exposure latitude, and minimize resist top loss thus improving the yield.

San Marco C-2 (San Marco-4) Post Launch Report No. 1

NASA Technical Reports Server (NTRS)

1974-01-01

The San Marco C-2 spacecraft, now designated San Marco-4, was successfully launched by a Scout vehicle from the San Marco Platform on 18 February 1974 at 6:05 a.m. EDT. The launch occurred 2 hours 50 minutes into the 3-hour window due co low cloud cover at the launch site. All spacecraft subsystems have been checked and are functioning normally. The protective caps for the two U.S. experiments were ejected and the Omegatron experiment activated on 19 February. The neutral mass spectrometer was activated as scheduled on 22 February after sufficient time to allow for spacecraft outgassing and to avoid the possibility of corona occurring. Both instruments are performing properly and worthwhile scientific data is being acquired.

A Multimedia Tutorial for Charged-Particle Beam Dynamics. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Silbar, Richard R.

1999-07-26

In September 1995 WhistleSoft, Inc., began developing a computer-based multimedia tutorial for charged-particle beam dynamics under Phase II of a Small Business Innovative Research grant from the U.S. Department of Energy. In Phase I of this project (see its Final Report) we had developed several prototype multimedia modules using an authoring system on NeXTStep computers. Such a platform was never our intended target, and when we began Phase II we decided to make the change immediately to develop our tutorial modules for the Windows and Macintosh microcomputer market. This Report details our progress and accomplishments. It also gives a flavormore » of the look and feel of the presently available and upcoming modules.« less

Validation of the design of a high resolution all-reflection Michelson interferometer for atmospheric spectroscopy

NASA Astrophysics Data System (ADS)

Carlson, Scott M.

1993-06-01

The design of a high resolution plane grating all-reflection Michelson interferometer for ionospheric spectroscopy was analyzed using ray tracing techniques. This interferometer produces an interference pattern whose spatial frequency is wavelength dependent. The instrument is intended for remote observations of the atomic oxygen triplet emission line profile at 1304 A in the thermosphere from sounding rocket or satellite platforms. The device was modeled using the PC-based ray tracing application, DART, and results analyzed through fourier techniques using the PC with Windows version of the Interactive Data Language (IDL). Through these methods, instrument resolution, resolving power, and bandpass were determined. An analysis of the effects of aperture size and shape on instrument performance was also conducted.

A vector-product information retrieval system adapted to heterogeneous, distributed computing environments

NASA Technical Reports Server (NTRS)

Rorvig, Mark E.

1991-01-01

Vector-product information retrieval (IR) systems produce retrieval results superior to all other searching methods but presently have no commercial implementations beyond the personal computer environment. The NASA Electronic Library Systems (NELS) provides a ranked list of the most likely relevant objects in collections in response to a natural language query. Additionally, the system is constructed using standards and tools (Unix, X-Windows, Notif, and TCP/IP) that permit its operation in organizations that possess many different hosts, workstations, and platforms. There are no known commercial equivalents to this product at this time. The product has applications in all corporate management environments, particularly those that are information intensive, such as finance, manufacturing, biotechnology, and research and development.

Resonant second harmonic generation in a gallium nitride two-dimensional photonic crystal on silicon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zeng, Y.; Roland, I.; Checoury, X.

We demonstrate second harmonic generation in a gallium nitride photonic crystal cavity embedded in a two-dimensional free-standing photonic crystal platform on silicon. The photonic crystal nanocavity is optically pumped with a continuous-wave laser at telecom wavelengths in the transparency window of the nitride material. The harmonic generation is evidenced by the spectral range of the emitted signal, the quadratic power dependence vs. input power, and the spectral dependence of second harmonic signal. The harmonic emission pattern is correlated to the harmonic polarization generated by the second-order nonlinear susceptibilities χ{sub zxx}{sup (2)}, χ{sub zyy}{sup (2)} and the electric fields of the fundamentalmore » cavity mode.« less

Hyperspectral Imaging on the International Space Station: An Innovative Approach to Commercial Development of Space

NASA Technical Reports Server (NTRS)

2003-01-01

NASA s Space Partnership Division (SPD) was established to promote the commercial development of space by providing access to space ai opportunity to perform commercial research in the microgravity environment. NASA, through SPD, has established Research Partnership Centers (RPC s) that bring the government, universities at private industry together to perform research in space for commercial applica!.!lons. The SPD Office has fostered a re!ationship between an RPC and an aerospace company to perform hyperspectral imaging on the Window Observational Research Facility (WORF) on board the International Space Station (ISS). As a result of this relationship and M the capabilities of the WORF, the ISS will serve the private sector with platform to conduct hyperspectral imaging for commercial research.

AMIDE: a free software tool for multimodality medical image analysis.

PubMed

Loening, Andreas Markus; Gambhir, Sanjiv Sam

2003-07-01

Amide's a Medical Image Data Examiner (AMIDE) has been developed as a user-friendly, open-source software tool for displaying and analyzing multimodality volumetric medical images. Central to the package's abilities to simultaneously display multiple data sets (e.g., PET, CT, MRI) and regions of interest is the on-demand data reslicing implemented within the program. Data sets can be freely shifted, rotated, viewed, and analyzed with the program automatically handling interpolation as needed from the original data. Validation has been performed by comparing the output of AMIDE with that of several existing software packages. AMIDE runs on UNIX, Macintosh OS X, and Microsoft Windows platforms, and it is freely available with source code under the terms of the GNU General Public License.

Human Spacecraft Structures Internship

NASA Technical Reports Server (NTRS)

Bhakta, Kush

2017-01-01

DSG will be placed in halo orbit around themoon- Platform for international/commercialpartners to explore lunar surface- Testbed for technologies needed toexplore Mars• Habitat module used to house up to 4crew members aboard the DSG- Launched on EM-3- Placed inside SLS fairing Habitat Module - Task Habitat Finite Element Model Re-modeled entire structure in NX2) Used Beam and Shell elements torepresent the pressure vessel structure3) Created a point cloud of centers of massfor mass components- Can now inspect local moments andinertias for thrust ring application8/ Habitat Structure – Docking Analysis Problem: Artificial Gravity may be necessary forastronaut health in deep spaceGoal: develop concepts that show how artificialgravity might be incorporated into a spacecraft inthe near term Orion Window Radiant Heat Testing.

TmoleX--a graphical user interface for TURBOMOLE.

PubMed

Steffen, Claudia; Thomas, Klaus; Huniar, Uwe; Hellweg, Arnim; Rubner, Oliver; Schroer, Alexander

2010-12-01

We herein present the graphical user interface (GUI) TmoleX for the quantum chemical program package TURBOMOLE. TmoleX allows users to execute the complete workflow of a quantum chemical investigation from the initial building of a structure to the visualization of the results in a user friendly graphical front end. The purpose of TmoleX is to make TURBOMOLE easy to use and to provide a high degree of flexibility. Hence, it should be a valuable tool for most users from beginners to experts. The program is developed in Java and runs on Linux, Windows, and Mac platforms. It can be used to run calculations on local desktops as well as on remote computers. © 2010 Wiley Periodicals, Inc.

gkmSVM: an R package for gapped-kmer SVM.

PubMed

Ghandi, Mahmoud; Mohammad-Noori, Morteza; Ghareghani, Narges; Lee, Dongwon; Garraway, Levi; Beer, Michael A

2016-07-15

We present a new R package for training gapped-kmer SVM classifiers for DNA and protein sequences. We describe an improved algorithm for kernel matrix calculation that speeds run time by about 2 to 5-fold over our original gkmSVM algorithm. This package supports several sequence kernels, including: gkmSVM, kmer-SVM, mismatch kernel and wildcard kernel. gkmSVM package is freely available through the Comprehensive R Archive Network (CRAN), for Linux, Mac OS and Windows platforms. The C ++ implementation is available at www.beerlab.org/gkmsvm mghandi@gmail.com or mbeer@jhu.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Robust and unobtrusive algorithm based on position independence for step detection

NASA Astrophysics Data System (ADS)

Qiu, KeCheng; Li, MengYang; Luo, YiHan

2018-04-01

Running is becoming one of the most popular exercises among the people, monitoring steps can help users better understand their running process and improve exercise efficiency. In this paper, we design and implement a robust and unobtrusive algorithm based on position independence for step detection under real environment. It applies Butterworth filter to suppress high frequency interference and then employs the projection based on mathematics to transform system to solve the problem of unknown position of smartphone. Finally, using sliding window to suppress the false peak. The algorithm was tested for eight participants on the Android 7.0 platform. In our experiments, the results show that the proposed algorithm can achieve desired effect in spite of device pose.

Using OpenOffice as a Portable Interface to JAVA-Based Applications

NASA Astrophysics Data System (ADS)

Comeau, T.; Garrett, B.; Richon, J.; Romelfanger, F.

2004-07-01

STScI previously used Microsoft Word and Microsoft Access, a Sybase ODBC driver, and the Adobe Acrobat PDF writer, along with a substantial amount of Visual Basic, to generate a variety of documents for the internal Space Telescope Grants Administration System (STGMS). While investigating an upgrade to Microsoft Office XP, we began considering alternatives, ultimately selecting an open source product, OpenOffice.org. This reduces the total number of products required to operate the internal STGMS system, simplifies the build system, and opens the possibility of moving to a non-Windows platform. We describe the experience of moving from Microsoft Office to OpenOffice.org, and our other internal uses of OpenOffice.org in our development environment.

nodeGame: Real-time, synchronous, online experiments in the browser.

PubMed

Balietti, Stefano

2017-10-01

nodeGame is a free, open-source JavaScript/ HTML5 framework for conducting synchronous experiments online and in the lab directly in the browser window. It is specifically designed to support behavioral research along three dimensions: (i) larger group sizes, (ii) real-time (but also discrete time) experiments, and (iii) batches of simultaneous experiments. nodeGame has a modular source code, and defines an API (application programming interface) through which experimenters can create new strategic environments and configure the platform. With zero-install, nodeGame can run on a great variety of devices, from desktop computers to laptops, smartphones, and tablets. The current version of the software is 3.0, and extensive documentation is available on the wiki pages at http://nodegame.org .

Photonic crystal ring resonator-based four-channel dense wavelength division multiplexing demultiplexer on silicon on insulator platform: design and analysis

NASA Astrophysics Data System (ADS)

Sreenivasulu, Tupakula; Bhowmick, Kaustav; Samad, Shafeek A.; Yadunath, Thamerassery Illam R.; Badrinarayana, Tarimala; Hegde, Gopalkrishna; Srinivas, Talabattula

2018-04-01

A micro/nanofabrication feasible compact photonic crystal (PC) ring-resonator-based channel drop filter has been designed and analyzed for operation in C and L bands of communication window. The four-channel demultiplexer consists of ring resonators of holes in two-dimensional PC slab. The proposed assembly design of dense wavelength division multiplexing setup is shown to achieve optimal quality factor, without altering the lattice parameters or resonator size or inclusion of scattering holes. Transmission characteristics are analyzed using the three-dimensional finite-difference time-domain simulation approach. The radiation loss of the ring resonator was minimized by forced cancelation of radiation fields by fine-tuning the air holes inside the ring resonator. An average cross talk of -34 dB has been achieved between the adjacent channels maintaining an average quality factor of 5000. Demultiplexing is achieved by engineering only the air holes inside the ring, which makes it a simple and tolerant design from the fabrication perspective. Also, the device footprint of 500 μm2 on silicon on insulator platform makes it easy to fabricate the device using e-beam lithography technique.

Performance of commercial platforms for rapid genotyping of polymorphisms affecting warfarin dose.

PubMed

King, Cristi R; Porche-Sorbet, Rhonda M; Gage, Brian F; Ridker, Paul M; Renaud, Yannick; Phillips, Michael S; Eby, Charles

2008-06-01

Initiation of warfarin therapy is associated with bleeding owing to its narrow therapeutic window and unpredictable therapeutic dose. Pharmacogenetic-based dosing algorithms can improve accuracy of initial warfarin dosing but require rapid genotyping for cytochrome P-450 2C9 (CYP2C9) *2 and *3 single nucleotide polymorphisms (SNPs) and a vitamin K epoxide reductase (VKORC1) SNP. We evaluated 4 commercial systems: INFINITI analyzer (AutoGenomics, Carlsbad, CA), Invader assay (Third Wave Technologies, Madison, WI), Tag-It Mutation Detection assay (Luminex Molecular Diagnostics, formerly Tm Bioscience, Toronto, Canada), and Pyrosequencing (Biotage, Uppsala, Sweden). We genotyped 112 DNA samples and resolved any discrepancies with bidirectional sequencing. The INFINITI analyzer was 100% accurate for all SNPs and required 8 hours. Invader and Tag-It were 100% accurate for CYP2C9 SNPs, 99% accurate for VKORC1 -1639/3673 SNP, and required 3 hours and 8 hours, respectively. Pyrosequencing was 99% accurate for CYP2C9 *2, 100% accurate for CYP2C9 *3, and 100% accurate for VKORC1 and required 4 hours. Current commercial platforms provide accurate and rapid genotypes for pharmacogenetic dosing during initiation of warfarin therapy.

Multidisciplinary Tool for Systems Analysis of Planetary Entry, Descent, and Landing

NASA Technical Reports Server (NTRS)

Samareh, Jamshid A.

2011-01-01

Systems analysis of a planetary entry (SAPE), descent, and landing (EDL) is a multidisciplinary activity in nature. SAPE improves the performance of the systems analysis team by automating and streamlining the process, and this improvement can reduce the errors that stem from manual data transfer among discipline experts. SAPE is a multidisciplinary tool for systems analysis of planetary EDL for Venus, Earth, Mars, Jupiter, Saturn, Uranus, Neptune, and Titan. It performs EDL systems analysis for any planet, operates cross-platform (i.e., Windows, Mac, and Linux operating systems), uses existing software components and open-source software to avoid software licensing issues, performs low-fidelity systems analysis in one hour on a computer that is comparable to an average laptop, and keeps discipline experts in the analysis loop. SAPE uses Python, a platform-independent, open-source language, for integration and for the user interface. Development has relied heavily on the object-oriented programming capabilities that are available in Python. Modules are provided to interface with commercial and government off-the-shelf software components (e.g., thermal protection systems and finite-element analysis). SAPE currently includes the following analysis modules: geometry, trajectory, aerodynamics, aerothermal, thermal protection system, and interface for structural sizing.

Research on spatio-temporal database techniques for spatial information service

NASA Astrophysics Data System (ADS)

Zhao, Rong; Wang, Liang; Li, Yuxiang; Fan, Rongshuang; Liu, Ping; Li, Qingyuan

2007-06-01

Geographic data should be described by spatial, temporal and attribute components, but the spatio-temporal queries are difficult to be answered within current GIS. This paper describes research into the development and application of spatio-temporal data management system based upon GeoWindows GIS software platform which was developed by Chinese Academy of Surveying and Mapping (CASM). Faced the current and practical requirements of spatial information application, and based on existing GIS platform, one kind of spatio-temporal data model which integrates vector and grid data together was established firstly. Secondly, we solved out the key technique of building temporal data topology, successfully developed a suit of spatio-temporal database management system adopting object-oriented methods. The system provides the temporal data collection, data storage, data management and data display and query functions. Finally, as a case study, we explored the application of spatio-temporal data management system with the administrative region data of multi-history periods of China as the basic data. With all the efforts above, the GIS capacity of management and manipulation in aspect of time and attribute of GIS has been enhanced, and technical reference has been provided for the further development of temporal geographic information system (TGIS).

A Novel and Freely Available Interactive 3d Model of the Internal Carotid Artery.

PubMed

Valera-Melé, Marc; Puigdellívol-Sánchez, Anna; Mavar-Haramija, Marija; Juanes-Méndez, Juan A; San-Román, Luis; de Notaris, Matteo; Prats-Galino, Alberto

2018-03-05

We describe a new and freely available 3D interactive model of the intracranial internal carotid artery (ICA) and the skull base that also allows to display and compare its main segment classifications. High-resolution 3D human angiography (isometric voxel's size 0.36 mm) and Computed Tomography angiography images were exported to Virtual Reality Modeling Language (VRML) format for processing in a 3D software platform and embedding in a 3D Portable Document Format (PDF) document that can be freely downloaded at http://diposit.ub.edu/dspace/handle/2445/112442 and runs under Acrobat Reader on Mac and Windows computers and Windows 10 tablets. The 3D-PDF allows for visualisation and interaction through JavaScript-based functions (including zoom, rotation, selective visualization and transparentation of structures or a predefined sequence view of the main segment classifications if desired). The ICA and its main branches and loops, the Gasserian ganglion, the petrolingual ligament and the proximal and distal dural rings within the skull base environment (anterior and posterior clinoid processes, silla turcica, ethmoid and sphenoid bones, orbital fossae) may be visualized from different perspectives. This interactive 3D-PDF provides virtual views of the ICA and becomes an innovative tool to improve the understanding of the neuroanatomy of the ICA and surrounding structures.

GPFrontend and GPGraphics: graphical analysis tools for genetic association studies.

PubMed

Uebe, Steffen; Pasutto, Francesca; Krumbiegel, Mandy; Schanze, Denny; Ekici, Arif B; Reis, André

2010-09-21

Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. Graphical output is often not intended or supposed to be performed with other command line tools, e.g. gnuplot. Using the Microsoft .NET 2.0 platform and Visual Studio 2005, we have created a graphical software package to analyze data from microarray whole genome association studies, both for a DNA-pooling based approach as well as regular single sample data. Part of this package was made to integrate with GenePool 0.8.2, a previously existing software suite for GNU/Linux systems, which we have modified to run in a Microsoft Windows environment. Further modifications cause it to generate some additional data. This enables GenePool to interact with the .NET parts created by us. The programs we developed are GPFrontend, a graphical user interface and frontend to use GenePool and create metadata files for it, and GPGraphics, a program to further analyze and graphically evaluate output of different WGA analysis programs, among them also GenePool. Our programs enable regular MS Windows users without much experience in bioinformatics to easily visualize whole genome data from a variety of sources.

Ultrafast selective transport of alkali metal ions in metal organic frameworks with subnanometer pores

PubMed Central

Zhang, Huacheng; Hou, Jue; Hu, Yaoxin; Wang, Peiyao; Ou, Ranwen; Jiang, Lei; Liu, Jefferson Zhe; Freeman, Benny D.; Hill, Anita J.; Wang, Huanting

2018-01-01

Porous membranes with ultrafast ion permeation and high ion selectivity are highly desirable for efficient mineral separation, water purification, and energy conversion, but it is still a huge challenge to efficiently separate monatomic ions of the same valence and similar sizes using synthetic membranes. We report metal organic framework (MOF) membranes, including ZIF-8 and UiO-66 membranes with uniform subnanometer pores consisting of angstrom-sized windows and nanometer-sized cavities for ultrafast selective transport of alkali metal ions. The angstrom-sized windows acted as ion selectivity filters for selection of alkali metal ions, whereas the nanometer-sized cavities functioned as ion conductive pores for ultrafast ion transport. The ZIF-8 and UiO-66 membranes showed a LiCl/RbCl selectivity of ~4.6 and ~1.8, respectively, which are much greater than the LiCl/RbCl selectivity of 0.6 to 0.8 measured in traditional porous membranes. Molecular dynamics simulations suggested that ultrafast and selective ion transport in ZIF-8 was associated with partial dehydration effects. This study reveals ultrafast and selective transport of monovalent ions in subnanometer MOF pores and opens up a new avenue to develop unique MOF platforms for efficient ion separations in the future. PMID:29487910

A personal digital assistant application (MobilDent) for dental fieldwork data collection, information management and database handling.

PubMed

Forsell, M; Häggström, M; Johansson, O; Sjögren, P

2008-11-08

To develop a personal digital assistant (PDA) application for oral health assessment fieldwork, including back-office and database systems (MobilDent). System design, construction and implementation of PDA, back-office and database systems. System requirements for MobilDent were collected, analysed and translated into system functions. User interfaces were implemented and system architecture was outlined. MobilDent was based on a platform with. NET (Microsoft) components, using an SQL Server 2005 (Microsoft) for data storage with Windows Mobile (Microsoft) operating system. The PDA devices were Dell Axim. System functions and user interfaces were specified for MobilDent. User interfaces for PDA, back-office and database systems were based on. NET programming. The PDA user interface was based on Windows suitable to a PDA display, whereas the back-office interface was designed for a normal-sized computer screen. A synchronisation module (MS Active Sync, Microsoft) was used to enable download of field data from PDA to the database. MobilDent is a feasible application for oral health assessment fieldwork, and the oral health assessment database may prove a valuable source for care planning, educational and research purposes. Further development of the MobilDent system will include wireless connectivity with download-on-demand technology.

Ultrafast selective transport of alkali metal ions in metal organic frameworks with subnanometer pores.

PubMed

Zhang, Huacheng; Hou, Jue; Hu, Yaoxin; Wang, Peiyao; Ou, Ranwen; Jiang, Lei; Liu, Jefferson Zhe; Freeman, Benny D; Hill, Anita J; Wang, Huanting

2018-02-01

Porous membranes with ultrafast ion permeation and high ion selectivity are highly desirable for efficient mineral separation, water purification, and energy conversion, but it is still a huge challenge to efficiently separate monatomic ions of the same valence and similar sizes using synthetic membranes. We report metal organic framework (MOF) membranes, including ZIF-8 and UiO-66 membranes with uniform subnanometer pores consisting of angstrom-sized windows and nanometer-sized cavities for ultrafast selective transport of alkali metal ions. The angstrom-sized windows acted as ion selectivity filters for selection of alkali metal ions, whereas the nanometer-sized cavities functioned as ion conductive pores for ultrafast ion transport. The ZIF-8 and UiO-66 membranes showed a LiCl/RbCl selectivity of ~4.6 and ~1.8, respectively, which are much greater than the LiCl/RbCl selectivity of 0.6 to 0.8 measured in traditional porous membranes. Molecular dynamics simulations suggested that ultrafast and selective ion transport in ZIF-8 was associated with partial dehydration effects. This study reveals ultrafast and selective transport of monovalent ions in subnanometer MOF pores and opens up a new avenue to develop unique MOF platforms for efficient ion separations in the future.

Preprocessing the Nintendo Wii Board Signal to Derive More Accurate Descriptors of Statokinesigrams.

PubMed

Audiffren, Julien; Contal, Emile

2016-08-01

During the past few years, the Nintendo Wii Balance Board (WBB) has been used in postural control research as an affordable but less reliable replacement for laboratory grade force platforms. However, the WBB suffers some limitations, such as a lower accuracy and an inconsistent sampling rate. In this study, we focus on the latter, namely the non uniform acquisition frequency. We show that this problem, combined with the poor signal to noise ratio of the WBB, can drastically decrease the quality of the obtained information if not handled properly. We propose a new resampling method, Sliding Window Average with Relevance Interval Interpolation (SWARII), specifically designed with the WBB in mind, for which we provide an open source implementation. We compare it with several existing methods commonly used in postural control, both on synthetic and experimental data. The results show that some methods, such as linear and piecewise constant interpolations should definitely be avoided, particularly when the resulting signal is differentiated, which is necessary to estimate speed, an important feature in postural control. Other methods, such as averaging on sliding windows or SWARII, perform significantly better on synthetic dataset, and produce results more similar to the laboratory-grade AMTI force plate (AFP) during experiments. Those methods should be preferred when resampling data collected from a WBB.

3-D photoacoustic and pulse echo imaging of prostate tumor progression in the mouse window chamber

NASA Astrophysics Data System (ADS)

Bauer, Daniel R.; Olafsson, Ragnar; Montilla, Leonardo G.; Witte, Russell S.

2011-02-01

Understanding the tumor microenvironment is critical to characterizing how cancers operate and predicting their response to treatment. We describe a novel, high-resolution coregistered photoacoustic (PA) and pulse echo (PE) ultrasound system used to image the tumor microenvironment. Compared to traditional optical systems, the platform provides complementary contrast and important depth information. Three mice are implanted with a dorsal skin flap window chamber and injected with PC-3 prostate tumor cells transfected with green fluorescent protein. The ensuing tumor invasion is mapped during three weeks or more using simultaneous PA and PE imaging at 25 MHz, combined with optical and fluorescent techniques. Pulse echo imaging provides details of tumor structure and the surrounding environment with 100-μm3 resolution. Tumor size increases dramatically with an average volumetric growth rate of 5.35 mm3/day, correlating well with 2-D fluorescent imaging (R = 0.97, p < 0.01). Photoacoustic imaging is able to track the underlying vascular network and identify hemorrhaging, while PA spectroscopy helps classify blood vessels according to their optical absorption spectrum, suggesting variation in blood oxygen saturation. Photoacoustic and PE imaging are safe, translational modalities that provide enhanced depth resolution and complementary contrast to track the tumor microenvironment, evaluate new cancer therapies, and develop molecular contrast agents in vivo.

MEA-Tools: an open source toolbox for the analysis of multi-electrode data with MATLAB.

PubMed

Egert, U; Knott, Th; Schwarz, C; Nawrot, M; Brandt, A; Rotter, S; Diesmann, M

2002-05-30

Recent advances in electrophysiological techniques have created new tools for the acquisition and storage of neuronal activity recorded simultaneously with numerous electrodes. These techniques support the analysis of the function as well as the structure of individual electrogenic cells in the context of surrounding neuronal or cardiac network. Commercially available tools for the analysis of such data, however, cannot be easily adapted to newly emerging requirements for data analysis and visualization, and cross compatibility between them is limited. In this report we introduce a free open source toolbox called microelectrode array tools (MEA-Tools) for the analysis of multi-electrode data based on the common data analysis environment MATLAB (version 5.3-6.1, The Mathworks, Natick, MA). The toolbox itself is platform independent. The file interface currently supports files recorded with MCRack (Multi Channel Systems, Reutlingen, Germany) under Microsoft Windows 95, 98, NT, and 2000, but can be adapted to other data acquisition systems. Functions are controlled via command line input and graphical user interfaces, and support common requirements for the analysis of local field potentials, extracellular spike activity, and continuous recordings, in addition to supplementary data acquired by additional instruments, e.g. intracellular amplifiers. Data may be processed as continuous recordings or time windows triggered to some event.

Preprocessing the Nintendo Wii Board Signal to Derive More Accurate Descriptors of Statokinesigrams

PubMed Central

Audiffren, Julien; Contal, Emile

2016-01-01

During the past few years, the Nintendo Wii Balance Board (WBB) has been used in postural control research as an affordable but less reliable replacement for laboratory grade force platforms. However, the WBB suffers some limitations, such as a lower accuracy and an inconsistent sampling rate. In this study, we focus on the latter, namely the non uniform acquisition frequency. We show that this problem, combined with the poor signal to noise ratio of the WBB, can drastically decrease the quality of the obtained information if not handled properly. We propose a new resampling method, Sliding Window Average with Relevance Interval Interpolation (SWARII), specifically designed with the WBB in mind, for which we provide an open source implementation. We compare it with several existing methods commonly used in postural control, both on synthetic and experimental data. The results show that some methods, such as linear and piecewise constant interpolations should definitely be avoided, particularly when the resulting signal is differentiated, which is necessary to estimate speed, an important feature in postural control. Other methods, such as averaging on sliding windows or SWARII, perform significantly better on synthetic dataset, and produce results more similar to the laboratory-grade AMTI force plate (AFP) during experiments. Those methods should be preferred when resampling data collected from a WBB. PMID:27490545

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitchell, Dean J.; Harding, Lee T.

Isotope identification algorithms that are contained in the Gamma Detector Response and Analysis Software (GADRAS) can be used for real-time stationary measurement and search applications on platforms operating under Linux or Android operating sys-tems. Since the background radiation can vary considerably due to variations in natu-rally-occurring radioactive materials (NORM), spectral algorithms can be substantial-ly more sensitive to threat materials than search algorithms based strictly on count rate. Specific isotopes or interest can be designated for the search algorithm, which permits suppression of alarms for non-threatening sources, such as such as medical radionuclides. The same isotope identification algorithms that are usedmore » for search ap-plications can also be used to process static measurements. The isotope identification algorithms follow the same protocols as those used by the Windows version of GADRAS, so files that are created under the Windows interface can be copied direct-ly to processors on fielded sensors. The analysis algorithms contain provisions for gain adjustment and energy lineariza-tion, which enables direct processing of spectra as they are recorded by multichannel analyzers. Gain compensation is performed by utilizing photopeaks in background spectra. Incorporation of this energy calibration tasks into the analysis algorithm also eliminates one of the more difficult challenges associated with development of radia-tion detection equipment.« less

NASGRO 3.0: A Software for Analyzing Aging Aircraft

NASA Technical Reports Server (NTRS)

Mettu, S. R.; Shivakumar, V.; Beek, J. M.; Yeh, F.; Williams, L. C.; Forman, R. G.; McMahon, J. J.; Newman, J. C., Jr.

1999-01-01

Structural integrity analysis of aging aircraft is a critical necessity in view of the increasing numbers of such aircraft in general aviation, the airlines and the military. Efforts are in progress by NASA, the FAA and the DoD to focus attention on aging aircraft safety. The present paper describes the NASGRO software which is well-suited for effectively analyzing the behavior of defects that may be found in aging aircraft. The newly revised Version 3.0 has many features specifically implemented to suit the needs of the aircraft community. The fatigue crack growth computer program NASA/FLAGRO 2.0 was originally developed to analyze space hardware such as the Space Shuttle, the International Space Station and the associated payloads. Due to popular demand, the software was enhanced to suit the needs of the aircraft industry. Major improvements in Version 3.0 are the incorporation of the ability to read aircraft spectra of unlimited size, generation of common aircraft fatigue load blocks, and the incorporation of crack-growth models which include load-interaction effects such as retardation due to overloads and acceleration due to underloads. Five new crack-growth models, viz., generalized Willenborg, modified generalized Willenborg, constant closure model, Walker-Chang model and the deKoning-Newman strip-yield model, have been implemented. To facilitate easier input of geometry, material properties and load spectra, a Windows-style graphical user interface has been developed. Features to quickly change the input and rerun the problem as well as examine the output are incorporated. NASGRO has been organized into three modules, the crack-growth module being the primary one. The other two modules are the boundary element module and the material properties module. The boundary-element module provides the ability to model and analyze complex two-dimensional problems to obtain stresses and stress-intensity factors. The material properties module allows users to store and curve-fit fatigue-crack growth data. On-line help and documentation are provided for each of the modules. In addition to the popular PC windows version, a unix-based X-windows version of NASGRO is also available. A portable C++ class library called WxWindows was used to facilitate cross-platform availability of the software.

Use of several Cloud Computing approaches for climate modelling: performance, costs and opportunities

NASA Astrophysics Data System (ADS)

Perez Montes, Diego A.; Añel Cabanelas, Juan A.; Wallom, David C. H.; Arribas, Alberto; Uhe, Peter; Caderno, Pablo V.; Pena, Tomas F.

2017-04-01

Cloud Computing is a technological option that offers great possibilities for modelling in geosciences. We have studied how two different climate models, HadAM3P-HadRM3P and CESM-WACCM, can be adapted in two different ways to run on Cloud Computing Environments from three different vendors: Amazon, Google and Microsoft. Also, we have evaluated qualitatively how the use of Cloud Computing can affect the allocation of resources by funding bodies and issues related to computing security, including scientific reproducibility. Our first experiments were developed using the well known ClimatePrediction.net (CPDN), that uses BOINC, over the infrastructure from two cloud providers, namely Microsoft Azure and Amazon Web Services (hereafter AWS). For this comparison we ran a set of thirteen month climate simulations for CPDN in Azure and AWS using a range of different virtual machines (VMs) for HadRM3P (50 km resolution over South America CORDEX region) nested in the global atmosphere-only model HadAM3P. These simulations were run on a single processor and took between 3 and 5 days to compute depending on the VM type. The last part of our simulation experiments was running WACCM over different VMS on the Google Compute Engine (GCE) and make a comparison with the supercomputer (SC) Finisterrae1 from the Centro de Supercomputacion de Galicia. It was shown that GCE gives better performance than the SC for smaller number of cores/MPI tasks but the model throughput shows clearly how the SC performance is better after approximately 100 cores (related with network speed and latency differences). From a cost point of view, Cloud Computing moves researchers from a traditional approach where experiments were limited by the available hardware resources to monetary resources (how many resources can be afforded). As there is an increasing movement and recommendation for budgeting HPC projects on this technology (budgets can be calculated in a more realistic way) we could see a shift on the trends over the next years to consolidate Cloud as the preferred solution.

[No-fault medical accidents: review of two years' activity of the regional commission for the compensation of medical accidents of the Provence-Alpes-Côtes d'Azur region (PACA)].

PubMed

Piercecchi-Marti, M-D; Sastre, B; Zuck, S; François, A; Genety, C; Bartoli, C; Leonetti, G

2008-01-01

Compensation for victims of medical accidents identified as no-fault medical accidents (NFMA) will be financed by national solidarity: this is a major and innovative feature of the Law of March 4, 2002 relative to Patients' Rights. In this review, we analyse the decisions of the regional commission on compensation of medical accidents in the Provence-Alpes-Côtes d'Azur (PACA) region of France in 2004 and 2005, and we attempt to identify the prevalence of certain surgical procedures liable to result in NFMA and to define the concept of "unintended consequences" in the context of state of health of the patient and the predictable course of the malady. We hope to improve the medical information given to the patient and thereby the overall quality of management. NFMA was acknowledged in 57 claims, about 10% of all those received by the commission during this period. Nearly half of the claims were within the competence of the commission because of the existence of serious sequelae (Permanent Partial Disability) in 47%. No typical profile of age or gender emerged in the patients with NFMA. The majority of cases occurred after surgical procedures, in particular gastrointestinal surgery and orthopaedic surgery; 91% were planned procedures. We did not identify increased risk related to any given type of surgery, particular disease condition, or precise anatomic region. Complications were those usually observed such as neurological complications in vascular surgery or perforations in gastrointestinal surgery. The interpretation of NFMA has undergone an evolution during this two-year period. In 2004, previous poor health status precluded acknowledgment of a medical accident, the argument being that there was a predisposition to the complication which occurred. In 2005, compensation was based on a reduced Partial Permanent Disability score compared to the patient's previous health status. This became a means of measuring the impact of the medical complication on an already predictably unfavorable clinical course without medical intervention, and the legal aspect of the "ineluctable nature" of this course.

Associations Between Serum Bone Biomarkers in Early Breast Cancer and Development of Bone Metastasis: Results From the AZURE (BIG01/04) Trial.

PubMed

Brown, Janet; Rathbone, Emma; Hinsley, Samantha; Gregory, Walter; Gossiel, Fatma; Marshall, Helen; Burkinshaw, Roger; Shulver, Helen; Thandar, Hasina; Bertelli, Gianfilippo; Maccon, Keane; Bowman, Angela; Hanby, Andrew; Bell, Richard; Cameron, David; Coleman, Robert

2018-02-07

Adjuvant therapies can prevent/delay bone metastasis development in breast cancer. We investigated whether serum bone turnover markers in early disease have clinical utility in identifying patients with a high risk of developing bone metastasis. Markers of bone formation (N-terminal propeptide of type-1 collagen [P1NP]) and bone resorption (C-telopeptide of type-1 collagen [CTX], pyridinoline cross-linked carboxy-terminal telopeptide of type-1 collagen [1-CTP]) were measured in baseline (pretreatment blood samples from 872 patients from a large randomized trial of adjuvant zoledronic acid (AZURE-ISRCTN79831382) in early breast cancer. Cox proportional hazards regression and cumulative incidence functions (adjusted for factors having a statistically significant effect on outcome) were used to investigate prognostic and predictive associations between recurrence events, bone marker levels, and clinical variables. All statistical tests were two-sided. When considered as continuous variables (log transformed), P1NP, CTX, and 1-CTP were each prognostic for future bone recurrence at any time (P = .006, P = .009, P = .008, respectively). Harrell's c-indices were a P1NP of 0.57 (95% confidence interval [CI] = 0.51 to 0.63), CTX of 0.57 (95% CI = 0.51 to 0.62), and 1-CTP of 0.57 (95% CI = 0.52 to 0.63). In categorical analyses based on the normal range, high baseline P1NP (>70 ng/mL) and CTX (>0.299 ng/mL), but not 1-CTP (>4.2 ng/mL), were also prognostic for future bone recurrence (P = .03, P = .03, P = .10, respectively). None of the markers were prognostic for overall distant recurrence; that is, they were bone metastasis specific, and none of the markers were predictive of treatment benefit from zoledronic acid. Serum P1NP, CTX, and 1-CTP are clinically useful, easily measured markers that show good prognostic ability (though low-to-moderate discrimination) for bone-specific recurrence and are worthy of further study. © The Author(s) 2018. Published by Oxford University Press.

ibex: An open infrastructure software platform to facilitate collaborative work in radiomics

PubMed Central

Zhang, Lifei; Fried, David V.; Fave, Xenia J.; Hunter, Luke A.; Court, Laurence E.

2015-01-01

Purpose: Radiomics, which is the high-throughput extraction and analysis of quantitative image features, has been shown to have considerable potential to quantify the tumor phenotype. However, at present, a lack of software infrastructure has impeded the development of radiomics and its applications. Therefore, the authors developed the imaging biomarker explorer (ibex), an open infrastructure software platform that flexibly supports common radiomics workflow tasks such as multimodality image data import and review, development of feature extraction algorithms, model validation, and consistent data sharing among multiple institutions. Methods: The ibex software package was developed using the matlab and c/c++ programming languages. The software architecture deploys the modern model-view-controller, unit testing, and function handle programming concepts to isolate each quantitative imaging analysis task, to validate if their relevant data and algorithms are fit for use, and to plug in new modules. On one hand, ibex is self-contained and ready to use: it has implemented common data importers, common image filters, and common feature extraction algorithms. On the other hand, ibex provides an integrated development environment on top of matlab and c/c++, so users are not limited to its built-in functions. In the ibex developer studio, users can plug in, debug, and test new algorithms, extending ibex’s functionality. ibex also supports quality assurance for data and feature algorithms: image data, regions of interest, and feature algorithm-related data can be reviewed, validated, and/or modified. More importantly, two key elements in collaborative workflows, the consistency of data sharing and the reproducibility of calculation result, are embedded in the ibex workflow: image data, feature algorithms, and model validation including newly developed ones from different users can be easily and consistently shared so that results can be more easily reproduced between institutions. Results: Researchers with a variety of technical skill levels, including radiation oncologists, physicists, and computer scientists, have found the ibex software to be intuitive, powerful, and easy to use. ibex can be run at any computer with the windows operating system and 1GB RAM. The authors fully validated the implementation of all importers, preprocessing algorithms, and feature extraction algorithms. Windows version 1.0 beta of stand-alone ibex and ibex’s source code can be downloaded. Conclusions: The authors successfully implemented ibex, an open infrastructure software platform that streamlines common radiomics workflow tasks. Its transparency, flexibility, and portability can greatly accelerate the pace of radiomics research and pave the way toward successful clinical translation. PMID:25735289

Space Station Furnace Facility Management Information System (SSFF-MIS) Development

NASA Technical Reports Server (NTRS)

Meade, Robert M.

1996-01-01

This report summarizes the chronology, results, and lessons learned from the development of the SSFF-MIS. This system has been nearly two years in development and has yielded some valuable insights into specialized MIS development. General: In December of 1994, the Camber Corporation and Science Applications International Corporation (SAIC) were contracted to design, develop, and implement a MIS for Marshall Space Flight Center's Space Station Furnace Facility Project. The system was to be accessible from both EBM-Compatible PC and Macintosh platforms. The system was required to contain data manually entered into the MIS as well as data imported from other MSFC sources. Electronic interfaces were established for each data source and retrieval was to be performed at prescribed time intervals. The SOW requirement that predominantly drove the development software selection was the dual-platform (IBM-PC and Macintosh) requirement. The requirement that the system would be maintained by Government personnel influenced the selection of Commercial Off-the-shelf software because of its inherent stability and readily available documentation and support. Microsoft FoxPro Professional 2.6 for Windows and Macintosh was selected as the development tool. This is a software development tool that has been in use for many years. It is stable and powerful. Microsoft has since released the replacement for this product, Microsoft Visual FoxPro, but at the time of this development, it was only available on the Windows platform. The initial contract included included the requirement for capabilities relating to the Work- and Organizational Breakdown Structures, cost (plan and actuals), workforce (plan and actuals), critical path scheduling, trend analysis, procurements and contracts, interface to manufacturing, Safety and Mission Assurance, risk analysis, and technical performance indicators. It also required full documentation of the system and training of users. During the course of the contract, the requirements for Safety and Mission Assurance interface, risk analysis, and technical performance indicators were deleted. Additional capabilities were added as reflected in the Contract Chronology below. Modification 4 added the requirement for Support Contractor manpower data, the ability to manually input data not imported from non-nal sources, a general 'health' indicator screen, and remote usage. Mod 6 included the ability to change the level of planning of Civil Service Manpower at any time and the ability to manually enter Op Codes in the manufacturing data where such codes were not provided by the EMPACS database. Modification 9 included a number of changes to report contents and formats. Modification 11 required the preparation of a detailed System Design Document.

IBEX: an open infrastructure software platform to facilitate collaborative work in radiomics.

PubMed

Zhang, Lifei; Fried, David V; Fave, Xenia J; Hunter, Luke A; Yang, Jinzhong; Court, Laurence E

2015-03-01

Radiomics, which is the high-throughput extraction and analysis of quantitative image features, has been shown to have considerable potential to quantify the tumor phenotype. However, at present, a lack of software infrastructure has impeded the development of radiomics and its applications. Therefore, the authors developed the imaging biomarker explorer (IBEX), an open infrastructure software platform that flexibly supports common radiomics workflow tasks such as multimodality image data import and review, development of feature extraction algorithms, model validation, and consistent data sharing among multiple institutions. The IBEX software package was developed using the MATLAB and c/c++ programming languages. The software architecture deploys the modern model-view-controller, unit testing, and function handle programming concepts to isolate each quantitative imaging analysis task, to validate if their relevant data and algorithms are fit for use, and to plug in new modules. On one hand, IBEX is self-contained and ready to use: it has implemented common data importers, common image filters, and common feature extraction algorithms. On the other hand, IBEX provides an integrated development environment on top of MATLAB and c/c++, so users are not limited to its built-in functions. In the IBEX developer studio, users can plug in, debug, and test new algorithms, extending IBEX's functionality. IBEX also supports quality assurance for data and feature algorithms: image data, regions of interest, and feature algorithm-related data can be reviewed, validated, and/or modified. More importantly, two key elements in collaborative workflows, the consistency of data sharing and the reproducibility of calculation result, are embedded in the IBEX workflow: image data, feature algorithms, and model validation including newly developed ones from different users can be easily and consistently shared so that results can be more easily reproduced between institutions. Researchers with a variety of technical skill levels, including radiation oncologists, physicists, and computer scientists, have found the IBEX software to be intuitive, powerful, and easy to use. IBEX can be run at any computer with the windows operating system and 1GB RAM. The authors fully validated the implementation of all importers, preprocessing algorithms, and feature extraction algorithms. Windows version 1.0 beta of stand-alone IBEX and IBEX's source code can be downloaded. The authors successfully implemented IBEX, an open infrastructure software platform that streamlines common radiomics workflow tasks. Its transparency, flexibility, and portability can greatly accelerate the pace of radiomics research and pave the way toward successful clinical translation.

Factors controlling air quality in different European subway systems.

PubMed

Martins, Vânia; Moreno, Teresa; Mendes, Luís; Eleftheriadis, Konstantinos; Diapouli, Evangelia; Alves, Célia A; Duarte, Márcio; de Miguel, Eladio; Capdevila, Marta; Querol, Xavier; Minguillón, María Cruz

2016-04-01

Sampling campaigns using the same equipment and methodology were conducted to assess and compare the air quality at three South European subway systems (Barcelona, Athens and Oporto), focusing on concentrations and chemical composition of PM2.5 on subway platforms, as well as PM2.5 concentrations inside trains. Experimental results showed that the mean PM2.5 concentrations widely varied among the European subway systems, and even among different platforms within the same underground system, which might be associated to distinct station and tunnel designs and ventilation systems. In all cases PM2.5 concentrations on the platforms were higher than those in the urban ambient air, evidencing that there is generation of PM2.5 associated with the subway systems operation. Subway PM2.5 consisted of elemental iron, total carbon, crustal matter, secondary inorganic compounds, insoluble sulphate, halite and trace elements. Of all metals, Fe was the most abundant, accounting for 29-43% of the total PM2.5 mass (41-61% if Fe2O3 is considered), indicating the existence of an Fe source in the subway system, which could have its origin in mechanical friction and wear processes between rails, wheels and brakes. The trace elements with the highest enrichment in the subway PM2.5 were Ba, Cu, Mn, Zn, Cr, Sb, Sr, Ni, Sn, Co, Zr and Mo. Similar PM2.5 diurnal trends were observed on platforms from different subway systems, with higher concentrations during subway operating hours than during the transport service interruption, and lower levels on weekends than on weekdays. PM2.5 concentrations depended largely on the operation and frequency of the trains and the ventilation system, and were lower inside the trains, when air conditioning system was operating properly, than on the platforms. However, the PM2.5 concentrations increased considerably when the train windows were open. The PM2.5 levels inside the trains decreased with the trains passage in aboveground sections. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

Robust Timing Synchronization in Aeronautical Mobile Communication Systems

NASA Technical Reports Server (NTRS)

Xiong, Fu-Qin; Pinchak, Stanley

2004-01-01

This work details a study of robust synchronization schemes suitable for satellite to mobile aeronautical applications. A new scheme, the Modified Sliding Window Synchronizer (MSWS), is devised and compared with existing schemes, including the traditional Early-Late Gate Synchronizer (ELGS), the Gardner Zero-Crossing Detector (GZCD), and the Sliding Window Synchronizer (SWS). Performance of the synchronization schemes is evaluated by a set of metrics that indicate performance in digital communications systems. The metrics are convergence time, mean square phase error (or root mean-square phase error), lowest SNR for locking, initial frequency offset performance, midstream frequency offset performance, and system complexity. The performance of the synchronizers is evaluated by means of Matlab simulation models. A simulation platform is devised to model the satellite to mobile aeronautical channel, consisting of a Quadrature Phase Shift Keying modulator, an additive white Gaussian noise channel, and a demodulator front end. Simulation results show that the MSWS provides the most robust performance at the cost of system complexity. The GZCD provides a good tradeoff between robustness and system complexity for communication systems that require high symbol rates or low overall system costs. The ELGS has a high system complexity despite its average performance. Overall, the SWS, originally designed for multi-carrier systems, performs very poorly in single-carrier communications systems. Table 5.1 in Section 5 provides a ranking of each of the synchronization schemes in terms of the metrics set forth in Section 4.1. Details of comparison are given in Section 5. Based on the results presented in Table 5, it is safe to say that the most robust synchronization scheme examined in this work is the high-sample-rate Modified Sliding Window Synchronizer. A close second is its low-sample-rate cousin. The tradeoff between complexity and lowest mean-square phase error determines the rankings of the Gardner Zero-Crossing Detector and both versions of the Early-Late Gate Synchronizer. The least robust models are the high and low-sample-rate Sliding Window Synchronizers. Consequently, the recommended replacement synchronizer for NASA's Advanced Air Transportation Technologies mobile aeronautical communications system is the high-sample-rate Modified Sliding Window Synchronizer. By incorporating this synchronizer into their system, NASA can be assured that their system will be operational in extremely adverse conditions. The quick convergence time of the MSWS should allow the use of high-level protocols. However, if NASA feels that reduced system complexity is the most important aspect of their replacement synchronizer, the Gardner Zero-Crossing Detector would be the best choice.

Earth Observations taken by the Expedition 13 crew

NASA Image and Video Library

2006-05-09

ISS013-E-16599 (9 May 2006) --- Wave sets and tidal currents in the Gulf of California are featured in this image photographed by an Expedition 13 crewmember on the International Space Station. In this image, sunglint off the Gulf of California gives the water a silver-gray appearance rather than the usual azure blue color. The sunglint allows us to see several active features which would not be visible otherwise. In this view of Punta Perihuete, Mexico we can see three major features: biological or man-made oils floating on the surface; the out-going tidal current; and complex wave patterns. The oils on the surface are recognizable as light grey, curved and variable-width streamers shaped by the local winds and currents. Plankton, fish, natural oil seeps and boats dumping bilges are all potential sources for these oils.

C-RED One : the infrared camera using the Saphira e-APD detector

NASA Astrophysics Data System (ADS)

Greffe, Timothée.; Feautrier, Philippe; Gach, Jean-Luc; Stadler, Eric; Clop, Fabien; Lemarchand, Stephane; Boutolleau, David; Baker, Ian

2016-08-01

Name for Person Card: Observatoire de la Côte d'Azur First Light Imaging' C-RED One infrared camera is capable of capturing up to 3500 full frames per second with a sub-electron readout noise and very low background. This breakthrough has been made possible thanks to the use of an e- APD infrared focal plane array which is a real disruptive technology in imagery. C-RED One is an autonomous system with an integrated cooling system and a vacuum regeneration system. It operates its sensor with a wide variety of read out techniques and processes video on-board thanks to an FPGA. We will show its performances and expose its main features. The project leading to this application has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement N° 673944.

Nanoelectronics enabled chronic multimodal neural platform in a mouse ischemic model

PubMed Central

Luan, Lan; Sullender, Colin T.; Li, Xue; Zhao, Zhengtuo; Zhu, Hanlin; Wei, Xiaoling; Xie, Chong; Dunn, Andrew K.

2018-01-01

Background Despite significant advancements of optical imaging techniques for mapping hemodynamics in small animal models, it remains challenging to combine imaging with spatially resolved electrical recording of individual neurons especially for longitudinal studies. This is largely due to the strong invasiveness to the living brain from the penetrating electrodes and their limited compatibility with longitudinal imaging. New Method We implant arrays of ultraflexible nanoelectronic threads (NETs) in mice for neural recording both at the brain surface and intracortically, which maintain great tissue compatibility chronically. By mounting a cranial window atop of the NET arrays that allows for chronic optical access, we establish a multimodal platform that combines spatially resolved electrical recording of neural activity and laser speckle contrast imaging (LSCI) of cerebral blood flow (CBF) for longitudinal studies. Results We induce peri-infarct depolarizations (PIDs) by targeted photothrombosis, and show the ability to detect its occurrence and propagation through spatiotemporal variations in both extracellular potentials and CBF. We also demonstrate chronic tracking of single-unit neural activity and CBF over days after photothrombosis, from which we observe reperfusion and increased firing rates. Comparison with Existing Method(s) This multimodal platform enables simultaneous mapping of neural activity and hemodynamic parameters at the microscale for quantitative, longitudinal comparisons with minimal perturbation to the baseline neurophysiology. Conclusion The ability to spatiotemporally resolve and chronically track CBF and neural electrical activity in the same living brain region has broad applications for studying the interplay between neural and hemodynamic responses in health and in cerebrovascular and neurological pathologies. PMID:29203409

Modelface: an Application Programming Interface (API) for Homology Modeling Studies Using Modeller Software

PubMed Central

Sakhteman, Amirhossein; Zare, Bijan

2016-01-01

An interactive application, Modelface, was presented for Modeller software based on windows platform. The application is able to run all steps of homology modeling including pdb to fasta generation, running clustal, model building and loop refinement. Other modules of modeler including energy calculation, energy minimization and the ability to make single point mutations in the PDB structures are also implemented inside Modelface. The API is a simple batch based application with no memory occupation and is free of charge for academic use. The application is also able to repair missing atom types in the PDB structures making it suitable for many molecular modeling studies such as docking and molecular dynamic simulation. Some successful instances of modeling studies using Modelface are also reported. PMID:28243276

Bio-Inspired Extreme Wetting Surfaces for Biomedical Applications

PubMed Central

Shin, Sera; Seo, Jungmok; Han, Heetak; Kang, Subin; Kim, Hyunchul; Lee, Taeyoon

2016-01-01

Biological creatures with unique surface wettability have long served as a source of inspiration for scientists and engineers. More specifically, materials exhibiting extreme wetting properties, such as superhydrophilic and superhydrophobic surfaces, have attracted considerable attention because of their potential use in various applications, such as self-cleaning fabrics, anti-fog windows, anti-corrosive coatings, drag-reduction systems, and efficient water transportation. In particular, the engineering of surface wettability by manipulating chemical properties and structure opens emerging biomedical applications ranging from high-throughput cell culture platforms to biomedical devices. This review describes design and fabrication methods for artificial extreme wetting surfaces. Next, we introduce some of the newer and emerging biomedical applications using extreme wetting surfaces. Current challenges and future prospects of the surfaces for potential biomedical applications are also addressed. PMID:28787916

Celeris: A GPU-accelerated open source software with a Boussinesq-type wave solver for real-time interactive simulation and visualization

NASA Astrophysics Data System (ADS)

Tavakkol, Sasan; Lynett, Patrick

2017-08-01

In this paper, we introduce an interactive coastal wave simulation and visualization software, called Celeris. Celeris is an open source software which needs minimum preparation to run on a Windows machine. The software solves the extended Boussinesq equations using a hybrid finite volume-finite difference method and supports moving shoreline boundaries. The simulation and visualization are performed on the GPU using Direct3D libraries, which enables the software to run faster than real-time. Celeris provides a first-of-its-kind interactive modeling platform for coastal wave applications and it supports simultaneous visualization with both photorealistic and colormapped rendering capabilities. We validate our software through comparison with three standard benchmarks for non-breaking and breaking waves.

A user-friendly means to scale from the biochemistry of photosynthesis to whole crop canopies and production in time and space - development of Java WIMOVAC.

PubMed

Song, Qingfeng; Chen, Dairui; Long, Stephen P; Zhu, Xin-Guang

2017-01-01

Windows Intuitive Model of Vegetation response to Atmosphere and Climate Change (WIMOVAC) has been used widely as a generic modular mechanistically rich model of plant production. It can predict the responses of leaf and canopy carbon balance, as well as production in different environmental conditions, in particular those relevant to global change. Here, we introduce an open source Java user-friendly version of WIMOVAC. This software is platform independent and can be easily downloaded to a laptop and used without any prior programming skills. In this article, we describe the structure, equations and user guide and illustrate some potential applications of WIMOVAC. © 2016 The Authors Plant, Cell & Environment Published by John Wiley & Sons Ltd.

SutraPrep, a pre-processor for SUTRA, a model for ground-water flow with solute or energy transport

USGS Publications Warehouse

Provost, Alden M.

2002-01-01

SutraPrep facilitates the creation of three-dimensional (3D) input datasets for the USGS ground-water flow and transport model SUTRA Version 2D3D.1. It is most useful for applications in which the geometry of the 3D model domain and the spatial distribution of physical properties and boundary conditions is relatively simple. SutraPrep can be used to create a SUTRA main input (?.inp?) file, an initial conditions (?.ics?) file, and a 3D plot of the finite-element mesh in Virtual Reality Modeling Language (VRML) format. Input and output are text-based. The code can be run on any platform that has a standard FORTRAN-90 compiler. Executable code is available for Microsoft Windows.

Expyriment: a Python library for cognitive and neuroscientific experiments.

PubMed

Krause, Florian; Lindemann, Oliver

2014-06-01

Expyriment is an open-source and platform-independent lightweight Python library for designing and conducting timing-critical behavioral and neuroimaging experiments. The major goal is to provide a well-structured Python library for script-based experiment development, with a high priority being the readability of the resulting program code. Expyriment has been tested extensively under Linux and Windows and is an all-in-one solution, as it handles stimulus presentation, the recording of input/output events, communication with other devices, and the collection and preprocessing of data. Furthermore, it offers a hierarchical design structure, which allows for an intuitive transition from the experimental design to a running program. It is therefore also suited for students, as well as for experimental psychologists and neuroscientists with little programming experience.

KSC-2009-5362

NASA Image and Video Library

2009-10-07

CAPE CANAVERAL, Fla. – In the Vehicle Assembly Building's High Bay 1 at NASA’s Kennedy Space Center in Florida, workers supervise space shuttle Atlantis as it is positioned next to an external fuel tank, at left, and pair of solid rocket boosters secured to a mobile launcher platform. Next, Atlantis will be attached, completing the stacking operation. Rollout of the completed shuttle stack to Kennedy’s Launch Pad 39A, a significant milestone in launch processing activities, is planned for Oct. 13. Liftoff of Atlantis on its STS-129 mission to the International Space Station is targeted for 4:04 p.m. EST Nov. 12 during a 10-minute launch window. For information on the STS-129 mission and crew, visit http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts129/index.html. Photo credit: NASA/Jack Pfaller

An efficient approach to the deployment of complex open source information systems

PubMed Central

Cong, Truong Van Chi; Groeneveld, Eildert

2011-01-01

Complex open source information systems are usually implemented as component-based software to inherit the available functionality of existing software packages developed by third parties. Consequently, the deployment of these systems not only requires the installation of operating system, application framework and the configuration of services but also needs to resolve the dependencies among components. The problem becomes more challenging when the application must be installed and used on different platforms such as Linux and Windows. To address this, an efficient approach using the virtualization technology is suggested and discussed in this paper. The approach has been applied in our project to deploy a web-based integrated information system in molecular genetics labs. It is a low-cost solution to benefit both software developers and end-users. PMID:22102770

Model driven development of clinical information sytems using openEHR.

PubMed

Atalag, Koray; Yang, Hong Yul; Tempero, Ewan; Warren, Jim

2011-01-01

openEHR and the recent international standard (ISO 13606) defined a model driven software development methodology for health information systems. However there is little evidence in the literature describing implementation; especially for desktop clinical applications. This paper presents an implementation pathway using .Net/C# technology for Microsoft Windows desktop platforms. An endoscopy reporting application driven by openEHR Archetypes and Templates has been developed. A set of novel GUI directives has been defined and presented which guides the automatic graphical user interface generator to render widgets properly. We also reveal the development steps and important design decisions; from modelling to the final software product. This might provide guidance for other developers and form evidence required for the adoption of these standards for vendors and national programs alike.

Proteomics to go: Proteomatic enables the user-friendly creation of versatile MS/MS data evaluation workflows.

PubMed

Specht, Michael; Kuhlgert, Sebastian; Fufezan, Christian; Hippler, Michael

2011-04-15

We present Proteomatic, an operating system independent and user-friendly platform that enables the construction and execution of MS/MS data evaluation pipelines using free and commercial software. Required external programs such as for peptide identification are downloaded automatically in the case of free software. Due to a strict separation of functionality and presentation, and support for multiple scripting languages, new processing steps can be added easily. Proteomatic is implemented in C++/Qt, scripts are implemented in Ruby, Python and PHP. All source code is released under the LGPL. Source code and installers for Windows, Mac OS X, and Linux are freely available at http://www.proteomatic.org. michael.specht@uni-muenster.de Supplementary data are available at Bioinformatics online.

THz characterization and demonstration of visible-transparent/terahertz-functional electromagnetic structures in ultra-conductive La-doped BaSnO3 Films.

PubMed

Arezoomandan, Sara; Prakash, Abhinav; Chanana, Ashish; Yue, Jin; Mao, Jieying; Blair, Steve; Nahata, Ajay; Jalan, Bharat; Sensale-Rodriguez, Berardi

2018-02-23

We report on terahertz characterization of La-doped BaSnO 3 (BSO) thin-films. BSO is a transparent complex oxide material, which has attracted substantial interest due to its large electrical conductivity and wide bandgap. The complex refractive index of these films is extracted in the 0.3 to 1.5 THz frequency range, which shows a metal-like response across this broad frequency window. The large optical conductivity found in these films at terahertz wavelengths makes this material an interesting platform for developing electromagnetic structures having a strong response at terahertz wavelengths, i.e. terahertz-functional, while being transparent at visible and near-IR wavelengths. As an example of such application, we demonstrate a visible-transparent terahertz polarizer.

Some stylized facts of the Bitcoin market

NASA Astrophysics Data System (ADS)

Bariviera, Aurelio F.; Basgall, María José; Hasperué, Waldo; Naiouf, Marcelo

2017-10-01

In recent years a new type of tradable assets appeared, generically known as cryptocurrencies. Among them, the most widespread is Bitcoin. Given its novelty, this paper investigates some statistical properties of the Bitcoin market. This study compares Bitcoin and standard currencies dynamics and focuses on the analysis of returns at different time scales. We test the presence of long memory in return time series from 2011 to 2017, using transaction data from one Bitcoin platform. We compute the Hurst exponent by means of the Detrended Fluctuation Analysis method, using a sliding window in order to measure long range dependence. We detect that Hurst exponents changes significantly during the first years of existence of Bitcoin, tending to stabilize in recent times. Additionally, multiscale analysis shows a similar behavior of the Hurst exponent, implying a self-similar process.

A Ubiquitous Optical Microsystem Platform with Application to Optical Metrology and Chemical Sensing

NASA Astrophysics Data System (ADS)

Gerling, John David

This dissertation is concerned with the development of a novel, versatile optical sensor platform for optical metrology and chemical sensing. We demonstrate the feasibility of embedding optical components between bonded silicon wafers with receptor cavities and optical windows to create a self-contained sensor microsystem that can be used for in-situ measurement of hostile environments. Arrays of these sensors internal to a silicon wafer can enable optical sensing for in-situ, real-time mapping and process development for the semiconductor industry in the form of an instrumented substrate. Single-die versions of these optical sensor platforms can also enable point-of-care diagnostics, high throughput disease screening, bio-warfare agent detection, and environmental monitoring. Our first discussion will focus on a single-wavelength interferometry-based prototype sensor. Several applications are demonstrated using this single wavelength prototype: refractive index monitoring, SiO2 plasma etching, chemical mechanical polishing, photoresist cure and dissolution, copper etch end-point detection, and also nanopore wetting phenomena. Subsequent sections of this dissertation will describe efforts to improve the optical sensor platform to achieve multi-wavelength sensing function. We explore the use of an off-the-shelf commercial RGB sensor for colorimetric monitoring of copper and aluminum thin-film etchings. We then expand upon our prior work and concepts to realize a fully integrated, chip-sized microspectrometer with a photon engine based on a diffraction grating. The design, fabrication, and demonstration of a working prototype with dimensions < 1 mm thick using standard planar microfabrication techniques is described. Proof-of-concept demonstrations indicate the working principle of dispersion, although with a low spectral resolution of 120 nm. With working knowledge of the issues of the first prototype, we present an improved 5-channel microspectrometer with a spectral range 400-900 nm and demonstrate its ability for spectral identification with 3 different phosphor powder samples. Finally, we conclude with suggestions for future areas of research.

MExLab Planetary Geoportal: 3D-access to planetary images and results of spatial data analysis

NASA Astrophysics Data System (ADS)

Karachevtseva, I.; Garov, A.

2015-10-01

MExLab Planetary Geoportal was developed as Geodesy and Cartography Node which provide access to results of study of celestial bodies such as DEM and orthoimages, as well as basemaps, crater catalogues and derivative products: slope, roughness, crater density (http://cartsrv.mexlab.ru/geoportal). The main feature of designed Geoportal is the ability of spatial queries and access to the contents selecting from the list of available data set (Phobos, Mercury, Moon, including Lunokhod's archive data). Prior version of Geoportal has been developed using Flash technology. Now we are developing new version which will use 3D-API (OpenGL, WebGL) based on shaders not only for standard 3D-functionality, but for 2D-mapping as well. Users can obtain quantitative and qualitative characteristics of the objects in graphical, tabular and 3D-forms. It will bring the advantages of unification of code and speed of processing and provide a number of functional advantages based on GIS-tools such as: - possibility of dynamic raster transform for needed map projection; - effective implementation of the co-registration of planetary images by combining spatial data geometries; - presentation in 3D-form different types of data, including planetary atmospheric measurements, subsurface radar data, ect. The system will be created with a new software architecture, which has a potential for development and flexibility in reconfiguration based on cross platform solution: - an application for the three types of platforms: desktop (Windows, Linux, OSX), web platform (any HTML5 browser), and mobile application (Android, iOS); - a single codebase shared between platforms (using cross compilation for Web); - a new telecommunication solution to connect between modules and external system like PROVIDE WebGIS (http://www.provide-space.eu/progis/). The research leading to these result was partly supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 312377 PRoViDE.

The role of the space station in earth science research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaye, Jack A.

1999-01-22

The International Space Station (ISS) has the potential to be a valuable platform for earth science research. By virtue of its being in a mid-inclination orbit (51.5 deg.), ISS provides the opportunity for nadir viewing of nearly 3/4 of the Earth's surface, and allows viewing to high latitudes if limb-emission or occultation viewing techniques are used. ISS also provides the opportunity for viewing the Earth under a range of lighting conditions, unlike the polar sun-synchronous satellites that are used for many earth observing programs. The ISS is expected to have ample power and data handling capability to support Earth-viewing instruments,more » provide opportunities for external mounting and retrieval of instruments, and be in place for a sufficiently long period that long-term data records can be obtained. On the other hand, there are several questions related to contamination, orbital variations, pointing knowledge and stability, and viewing that are of concern in consideration of ISS for earth science applications. The existence of an optical quality window (the Window Observational Research Facility, or WORF), also provides the opportunity for Earth observations from inside the pressurized part of ISS. Current plans by NASA for earth science research from ISS are built around the Stratospheric Aerosol and Gas Experiment (SAGE III) instrument, planned for launch in 2002.« less

Database for the collection and analysis of clinical data and images of neoplasms of the sinonasal tract.

PubMed

Trimarchi, Matteo; Lund, Valerie J; Nicolai, Piero; Pini, Massimiliano; Senna, Massimo; Howard, David J

2004-04-01

The Neoplasms of the Sinonasal Tract software package (NSNT v 1.0) implements a complete visual database for patients with sinonasal neoplasia, facilitating standardization of data and statistical analysis. The software, which is compatible with the Macintosh and Windows platforms, provides multiuser application with a dedicated server (on Windows NT or 2000 or Macintosh OS 9 or X and a network of clients) together with web access, if required. The system hardware consists of an Apple Power Macintosh G4500 MHz computer with PCI bus, 256 Mb of RAM plus 60 Gb hard disk, or any IBM-compatible computer with a Pentium 2 processor. Image acquisition may be performed with different frame-grabber cards for analog or digital video input of different standards (PAL, SECAM, or NTSC) and levels of quality (VHS, S-VHS, Betacam, Mini DV, DV). The visual database is based on 4th Dimension by 4D Inc, and video compression is made in real-time MPEG format. Six sections have been developed: demographics, symptoms, extent of disease, radiology, treatment, and follow-up. Acquisition of data includes computed tomography and magnetic resonance imaging, histology, and endoscopy images, allowing sequential comparison. Statistical analysis integral to the program provides Kaplan-Meier survival curves. The development of a dedicated, user-friendly database for sinonasal neoplasia facilitates a multicenter network and has obvious clinical and research benefits.

Sub-visual Cirrus detection and characterization

NASA Technical Reports Server (NTRS)

Schmidt, E.; Grams, G.; Patterson, E.

1990-01-01

Analysis of archived cold optics (COR) radiometer data is yielding useful information on the diurnal, geographic, seasonal and altitude variability of atmospheric background radiance levels in the 11 micron window region. This database is a compilation of Kuiper Infrared Technology Experiment (KITE) and Atmospheric Radiance Study (ARS) observations under a wide variety of conditions. Correlating the measurements from these two studies with the LOWTRAN model code has revealed several important results. First, the 11 micron window appears to be filled-in, i.e., the troughs on either side of the nitric acid peak are shallower than expected. Second, the amplitude of the background radiances measured exceeds the model predictions by a factor of 2 to 3 or more. This is thought to be due to the existence of thin, high altitude cirrus clouds (sub-visual cirrus) above the sensor platform. These high background levels are observed under quiescent conditions in the South Pacific (Marshall Islands), as well as over the continental United States (the West Coast). In the tropics, there appears to be little diurnal variability, a plausible seasonal variation and a linear dependence between 7.2 and 11.4 micron band data, indicating possible multi-spectral approaches to detection of sub-visual cirrus clouds. Theoretical analysis of the magnitude of the effects of a sub-visual cirrus cloud on atmospheric background radiances measured by a near-horizontal sensor is in progress.

SpecPad: device-independent NMR data visualization and processing based on the novel DART programming language and Html5 Web technology.

PubMed

Guigas, Bruno

2017-09-01

SpecPad is a new device-independent software program for the visualization and processing of one-dimensional and two-dimensional nuclear magnetic resonance (NMR) time domain (FID) and frequency domain (spectrum) data. It is the result of a project to investigate whether the novel programming language DART, in combination with Html5 Web technology, forms a suitable base to write an NMR data evaluation software which runs on modern computing devices such as Android, iOS, and Windows tablets as well as on Windows, Linux, and Mac OS X desktop PCs and notebooks. Another topic of interest is whether this technique also effectively supports the required sophisticated graphical and computational algorithms. SpecPad is device-independent because DART's compiled executable code is JavaScript and can, therefore, be run by the browsers of PCs and tablets. Because of Html5 browser cache technology, SpecPad may be operated off-line. Network access is only required during data import or export, e.g. via a Cloud service, or for software updates. A professional and easy to use graphical user interface consistent across all hardware platforms supports touch screen features on mobile devices for zooming and panning and for NMR-related interactive operations such as phasing, integration, peak picking, or atom assignment. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Low-cost real-time 3D PC distributed-interactive-simulation (DIS) application for C4I

NASA Astrophysics Data System (ADS)

Gonthier, David L.; Veron, Harry

1998-04-01

A 3D Distributed Interactive Simulation (DIS) application was developed and demonstrated in a PC environment. The application is capable of running in the stealth mode or as a player which includes battlefield simulations, such as ModSAF. PCs can be clustered together, but not necessarily collocated, to run a simulation or training exercise on their own. A 3D perspective view of the battlefield is displayed that includes terrain, trees, buildings and other objects supported by the DIS application. Screen update rates of 15 to 20 frames per second have been achieved with fully lit and textured scenes thus providing high quality and fast graphics. A complete PC system can be configured for under $2,500. The software runs under Windows95 and WindowsNT. It is written in C++ and uses a commercial API called RenderWare for 3D rendering. The software uses Microsoft Foundation classes and Microsoft DirectPlay for joystick input. The RenderWare libraries enhance the performance through optimization for MMX and the Pentium Pro processor. The RenderWare and the Righteous 3D graphics board from Orchid Technologies with an advertised rendering rate of up to 2 million texture mapped triangles per second. A low-cost PC DIS simulator that can partake in a real-time collaborative simulation with other platforms is thus achieved.

WILBER and PyWEED: Event-based Seismic Data Request Tools

NASA Astrophysics Data System (ADS)

Falco, N.; Clark, A.; Trabant, C. M.

2017-12-01

WILBER and PyWEED are two user-friendly tools for requesting event-oriented seismic data. Both tools provide interactive maps and other controls for browsing and filtering event and station catalogs, and downloading data for selected event/station combinations, where the data window for each event/station pair may be defined relative to the arrival time of seismic waves from the event to that particular station. Both tools allow data to be previewed visually, and can download data in standard miniSEED, SAC, and other formats, complete with relevant metadata for performing instrument correction. WILBER is a web application requiring only a modern web browser. Once the user has selected an event, WILBER identifies all data available for that time period, and allows the user to select stations based on criteria such as the station's distance and orientation relative to the event. When the user has finalized their request, the data is collected and packaged on the IRIS server, and when it is ready the user is sent a link to download. PyWEED is a downloadable, cross-platform (Macintosh / Windows / Linux) application written in Python. PyWEED allows a user to select multiple events and stations, and will download data for each event/station combination selected. PyWEED is built around the ObsPy seismic toolkit, and allows direct interaction and control of the application through a Python interactive console.

Underwater sky image as remote sensing instrument of sea roughness parameters and its variability

NASA Astrophysics Data System (ADS)

Molkov, Alexander A.; Dolin, Lev S.; Kapustin, Ivan A.; Sergievskaya, Irina A.; Shomina, Olga V.

2016-10-01

At present a sufficient amount of methods is offered for determining the characteristics of sea roughness in accordance with optical images of wavy water surface obtained from different near-shore constructions, sea platforms, vessels, aircraft and satellites. The most informative elements in this case are solar path and peripheral areas of the image free from sun glitters. However, underwater images of the surface obtained with the help of optical receiver located at a certain depth contain apart from the mentioned elements one more informative element- Snell's window. It is an underwater sky image which distortions of border contain information on roughness characteristics and serve as the indicator of its variability. The research offers the method for determining energy spectra of wind waves in accordance with the second statistical moment of Snell's window image. The results of testing of the offered method are provided based on natural images registered in the course of trip to the Black Sea under conditions of different wind and wave environment for clear surface and surface covered by surfactant films. For both cases frequency spectra of surface slopes are recovered and their good coincidence to the spectra received by processing of signals from a string wave recorder is established. Efficiency of application of the offered method for tasks of remote monitoring and environmental control of natural reservoirs is shown.

Tissue-specific exosome biomarkers for noninvasively monitoring immunologic rejection of transplanted tissue

PubMed Central

Korutla, Laxminarayana; Habertheuer, Andreas; Yu, Ming; Rostami, Susan; Yuan, Chao-Xing; Reddy, Sanjana; Korutla, Varun; Koeberlein, Brigitte; Trofe-Clark, Jennifer; Rickels, Michael R.; Naji, Ali

2017-01-01

In transplantation, there is a critical need for noninvasive biomarker platforms for monitoring immunologic rejection. We hypothesized that transplanted tissues release donor-specific exosomes into recipient circulation and that the quantitation and profiling of donor intra-exosomal cargoes may constitute a biomarker platform for monitoring rejection. Here, we have tested this hypothesis in a human-into-mouse xenogeneic islet transplant model and validated the concept in clinical settings of islet and renal transplantation. In the xenogeneic model, we quantified islet transplant exosomes in recipient blood over long-term follow-up using anti-HLA antibody, which was detectable only in xenoislet recipients of human islets. Transplant islet exosomes were purified using anti-HLA antibody–conjugated beads, and their cargoes contained the islet endocrine hormone markers insulin, glucagon, and somatostatin. Rejection led to a marked decrease in transplant islet exosome signal along with distinct changes in exosomal microRNA and proteomic profiles prior to appearance of hyperglycemia. In the clinical settings of islet and renal transplantation, donor exosomes with respective tissue specificity for islet β cells and renal epithelial cells were reliably characterized in recipient plasma over follow-up periods of up to 5 years. Collectively, these findings demonstrate the biomarker potential of transplant exosome characterization for providing a noninvasive window into the conditional state of transplant tissue. PMID:28319051

Large format geiger-mode avalanche photodiode LADAR camera

NASA Astrophysics Data System (ADS)

Yuan, Ping; Sudharsanan, Rengarajan; Bai, Xiaogang; Labios, Eduardo; Morris, Bryan; Nicholson, John P.; Stuart, Gary M.; Danny, Harrison

2013-05-01

Recently Spectrolab has successfully demonstrated a compact 32x32 Laser Detection and Range (LADAR) camera with single photo-level sensitivity with small size, weight, and power (SWAP) budget for threedimensional (3D) topographic imaging at 1064 nm on various platforms. With 20-kHz frame rate and 500- ps timing uncertainty, this LADAR system provides coverage down to inch-level fidelity and allows for effective wide-area terrain mapping. At a 10 mph forward speed and 1000 feet above ground level (AGL), it covers 0.5 square-mile per hour with a resolution of 25 in2/pixel after data averaging. In order to increase the forward speed to fit for more platforms and survey a large area more effectively, Spectrolab is developing 32x128 Geiger-mode LADAR camera with 43 frame rate. With the increase in both frame rate and array size, the data collection rate is improved by 10 times. With a programmable bin size from 0.3 ps to 0.5 ns and 14-bit timing dynamic range, LADAR developers will have more freedom in system integration for various applications. Most of the special features of Spectrolab 32x32 LADAR camera, such as non-uniform bias correction, variable range gate width, windowing for smaller arrays, and short pixel protection, are implemented in this camera.

Implementation of remote monitoring and managing switches

NASA Astrophysics Data System (ADS)

Leng, Junmin; Fu, Guo

2010-12-01

In order to strengthen the safety performance of the network and provide the big convenience and efficiency for the operator and the manager, the system of remote monitoring and managing switches has been designed and achieved using the advanced network technology and present network resources. The fast speed Internet Protocol Cameras (FS IP Camera) is selected, which has 32-bit RSIC embedded processor and can support a number of protocols. An Optimal image compress algorithm Motion-JPEG is adopted so that high resolution images can be transmitted by narrow network bandwidth. The architecture of the whole monitoring and managing system is designed and implemented according to the current infrastructure of the network and switches. The control and administrative software is projected. The dynamical webpage Java Server Pages (JSP) development platform is utilized in the system. SQL (Structured Query Language) Server database is applied to save and access images information, network messages and users' data. The reliability and security of the system is further strengthened by the access control. The software in the system is made to be cross-platform so that multiple operating systems (UNIX, Linux and Windows operating systems) are supported. The application of the system can greatly reduce manpower cost, and can quickly find and solve problems.

A cross-platform freeware tool for digital reconstruction of neuronal arborizations from image stacks.

PubMed

Brown, Kerry M; Donohue, Duncan E; D'Alessandro, Giampaolo; Ascoli, Giorgio A

2005-01-01

Digital reconstruction of neuronal arborizations is an important step in the quantitative investigation of cellular neuroanatomy. In this process, neurites imaged by microscopy are semi-manually traced through the use of specialized computer software and represented as binary trees of branching cylinders (or truncated cones). Such form of the reconstruction files is efficient and parsimonious, and allows extensive morphometric analysis as well as the implementation of biophysical models of electrophysiology. Here, we describe Neuron_ Morpho, a plugin for the popular Java application ImageJ that mediates the digital reconstruction of neurons from image stacks. Both the executable and code of Neuron_ Morpho are freely distributed (www.maths. soton.ac.uk/staff/D'Alessandro/morpho or www.krasnow.gmu.edu/L-Neuron), and are compatible with all major computer platforms (including Windows, Mac, and Linux). We tested Neuron_Morpho by reconstructing two neurons from each of the two preparations representing different brain areas (hippocampus and cerebellum), neuritic type (pyramidal cell dendrites and olivar axonal projection terminals), and labeling method (rapid Golgi impregnation and anterograde dextran amine), and quantitatively comparing the resulting morphologies to those of the same cells reconstructed with the standard commercial system, Neurolucida. None of the numerous morphometric measures that were analyzed displayed any significant or systematic difference between the two reconstructing systems.

PASMet: a web-based platform for prediction, modelling and analyses of metabolic systems

PubMed Central

Sriyudthsak, Kansuporn; Mejia, Ramon Francisco; Arita, Masanori; Hirai, Masami Yokota

2016-01-01

PASMet (Prediction, Analysis and Simulation of Metabolic networks) is a web-based platform for proposing and verifying mathematical models to understand the dynamics of metabolism. The advantages of PASMet include user-friendliness and accessibility, which enable biologists and biochemists to easily perform mathematical modelling. PASMet offers a series of user-functions to handle the time-series data of metabolite concentrations. The functions are organised into four steps: (i) Prediction of a probable metabolic pathway and its regulation; (ii) Construction of mathematical models; (iii) Simulation of metabolic behaviours; and (iv) Analysis of metabolic system characteristics. Each function contains various statistical and mathematical methods that can be used independently. Users who may not have enough knowledge of computing or programming can easily and quickly analyse their local data without software downloads, updates or installations. Users only need to upload their files in comma-separated values (CSV) format or enter their model equations directly into the website. Once the time-series data or mathematical equations are uploaded, PASMet automatically performs computation on server-side. Then, users can interactively view their results and directly download them to their local computers. PASMet is freely available with no login requirement at http://pasmet.riken.jp/ from major web browsers on Windows, Mac and Linux operating systems. PMID:27174940

Current-Driven Dynamics of Skyrmions Stabilized in MnSi Nanowires Revealed by Topological Hall Effect

NASA Astrophysics Data System (ADS)

Liang, Dong; Degrave, John; Stolt, Matthew; Tokura, Yoshinori; Jin, Song

2015-03-01

Skyrmions, novel topologically stable spin vortices, hold promise for next-generation high-density magnetic storage technologies due to their nanoscale domains and ultralow energy consumption. One-dimensional (1D) nanowires are ideal hosts for skyrmions since they not only serve as a natural platform for magnetic racetrack memory devices but also can potentially stabilize skyrmions. We use the topological Hall effect (THE) to study the phase stability and current-driven dynamics of the skyrmions in MnSi nanowires. The THE was observed in an extended magnetic field-temperature window (15 to 30 K), suggesting stabilization of skyrmion phase in nanowires compared with the bulk (27 to 29.5 K). Furthermore, we study skyrmion dynamics in this extended skyrmion phase region and found that under the high current-density of 108-109Am-2 enabled by nanowire geometry, the THE decreases with increasing current densities, which demonstrates the current-driven motion of skyrmions generating the emergent electric field. These results open up the exploration of nanowires as an attractive platform for investigating skyrmion physics in 1D systems and exploiting skyrmions in magnetic storage concepts. This work is supported by US National Science Foundation (ECCS-1231916) and JSPS Grant-in-Aid for Scientific Research No. 24224009.

Photosensitivity enhancement with TiO2 in semitransparent light-sensitive skins of nanocrystal monolayers.

PubMed

Akhavan, Shahab; Yeltik, Aydan; Demir, Hilmi Volkan

2014-06-25

We propose and demonstrate light-sensitive nanocrystal skins that exhibit broadband sensitivity enhancement based on electron transfer to a thin TiO2 film grown by atomic layer deposition. In these photosensors, which operate with no external bias, photogenerated electrons remain trapped inside the nanocrystals. These electrons generally recombine with the photogenerated holes that accumulate at the top interfacing contact, which leads to lower photovoltage buildup. Because favorable conduction band offset aids in transferring photoelectrons from CdTe nanocrystals to the TiO2 layer, which decreases the exciton recombination probability, TiO2 has been utilized as the electron-accepting material in these light-sensitive nanocrystal skins. A controlled interface thickness between the TiO2 layer and the monolayer of CdTe nanocrystals enables a photovoltage buildup enhancement in the proposed nanostructure platform. With TiO2 serving as the electron acceptor, we observed broadband sensitivity improvement across 350-475 nm, with an approximately 22% enhancement. Furthermore, time-resolved fluorescence measurements verified the electron transfer from the CdTe nanocrystals to the TiO2 layer in light-sensitive skins. These results could pave the way for engineering nanocrystal-based light-sensing platforms, such as smart transparent windows, light-sensitive walls, and large-area optical detection systems.

Relative azimuth inversion by way of damped maximum correlation estimates

USGS Publications Warehouse

Ringler, A.T.; Edwards, J.D.; Hutt, C.R.; Shelly, F.

2012-01-01

Horizontal seismic data are utilized in a large number of Earth studies. Such work depends on the published orientations of the sensitive axes of seismic sensors relative to true North. These orientations can be estimated using a number of different techniques: SensOrLoc (Sensitivity, Orientation and Location), comparison to synthetics (Ekstrom and Busby, 2008), or by way of magnetic compass. Current methods for finding relative station azimuths are unable to do so with arbitrary precision quickly because of limitations in the algorithms (e.g. grid search methods). Furthermore, in order to determine instrument orientations during station visits, it is critical that any analysis software be easily run on a large number of different computer platforms and the results be obtained quickly while on site. We developed a new technique for estimating relative sensor azimuths by inverting for the orientation with the maximum correlation to a reference instrument, using a non-linear parameter estimation routine. By making use of overlapping windows, we are able to make multiple azimuth estimates, which helps to identify the confidence of our azimuth estimate, even when the signal-to-noise ratio (SNR) is low. Finally, our algorithm has been written as a stand-alone, platform independent, Java software package with a graphical user interface for reading and selecting data segments to be analyzed.

Intellectual Production Supervision Perform based on RFID Smart Electricity Meter

NASA Astrophysics Data System (ADS)

Chen, Xiangqun; Huang, Rui; Shen, Liman; chen, Hao; Xiong, Dezhi; Xiao, Xiangqi; Liu, Mouhai; Xu, Renheng

2018-03-01

This topic develops the RFID intelligent electricity meter production supervision project management system. The system is designed for energy meter production supervision in the management of the project schedule, quality and cost information management requirements in RFID intelligent power, and provide quantitative information more comprehensive, timely and accurate for supervision engineer and project manager management decisions, and to provide technical information for the product manufacturing stage file. From the angle of scheme analysis, design, implementation and test, the system development of production supervision project management system for RFID smart meter project is discussed. Focus on the development of the system, combined with the main business application and management mode at this stage, focuses on the energy meter to monitor progress information, quality information and cost based information on RFID intelligent power management function. The paper introduces the design scheme of the system, the overall client / server architecture, client oriented graphical user interface universal, complete the supervision of project management and interactive transaction information display, the server system of realizing the main program. The system is programmed with C# language and.NET operating environment, and the client and server platforms use Windows operating system, and the database server software uses Oracle. The overall platform supports mainstream information and standards and has good scalability.

A future Outlook: Web based Simulation of Hydrodynamic models

NASA Astrophysics Data System (ADS)

Islam, A. S.; Piasecki, M.

2003-12-01

Despite recent advances to present simulation results as 3D graphs or animation contours, the modeling user community still faces some shortcomings when trying to move around and analyze data. Typical problems include the lack of common platforms with standard vocabulary to exchange simulation results from different numerical models, insufficient descriptions about data (metadata), lack of robust search and retrieval tools for data, and difficulties to reuse simulation domain knowledge. This research demonstrates how to create a shared simulation domain in the WWW and run a number of models through multi-user interfaces. Firstly, meta-datasets have been developed to describe hydrodynamic model data based on geographic metadata standard (ISO 19115) that has been extended to satisfy the need of the hydrodynamic modeling community. The Extended Markup Language (XML) is used to publish this metadata by the Resource Description Framework (RDF). Specific domain ontology for Web Based Simulation (WBS) has been developed to explicitly define vocabulary for the knowledge based simulation system. Subsequently, this knowledge based system is converted into an object model using Meta Object Family (MOF). The knowledge based system acts as a Meta model for the object oriented system, which aids in reusing the domain knowledge. Specific simulation software has been developed based on the object oriented model. Finally, all model data is stored in an object relational database. Database back-ends help store, retrieve and query information efficiently. This research uses open source software and technology such as Java Servlet and JSP, Apache web server, Tomcat Servlet Engine, PostgresSQL databases, Protégé ontology editor, RDQL and RQL for querying RDF in semantic level, Jena Java API for RDF. Also, we use international standards such as the ISO 19115 metadata standard, and specifications such as XML, RDF, OWL, XMI, and UML. The final web based simulation product is deployed as Web Archive (WAR) files which is platform and OS independent and can be used by Windows, UNIX, or Linux. Keywords: Apache, ISO 19115, Java Servlet, Jena, JSP, Metadata, MOF, Linux, Ontology, OWL, PostgresSQL, Protégé, RDF, RDQL, RQL, Tomcat, UML, UNIX, Windows, WAR, XML

SU-E-J-123: Assessing Segmentation Accuracy of Internal Volumes and Sub-Volumes in 4D PET/CT of Lung Tumors Using a Novel 3D Printed Phantom

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soultan, D; Murphy, J; James, C

2015-06-15

Purpose: To assess the accuracy of internal target volume (ITV) segmentation of lung tumors for treatment planning of simultaneous integrated boost (SIB) radiotherapy as seen in 4D PET/CT images, using a novel 3D-printed phantom. Methods: The insert mimics high PET tracer uptake in the core and 50% uptake in the periphery, by using a porous design at the periphery. A lung phantom with the insert was placed on a programmable moving platform. Seven breathing waveforms of ideal and patient-specific respiratory motion patterns were fed to the platform, and 4D PET/CT scans were acquired of each of them. CT images weremore » binned into 10 phases, and PET images were binned into 5 phases following the clinical protocol. Two scenarios were investigated for segmentation: a gate 30–70 window, and no gating. The radiation oncologist contoured the outer ITV of the porous insert with on CT images, while the internal void volume with 100% uptake was contoured on PET images for being indistinguishable from the outer volume in CT images. Segmented ITVs were compared to the expected volumes based on known target size and motion. Results: 3 ideal breathing patterns, 2 regular-breathing patient waveforms, and 2 irregular-breathing patient waveforms were used for this study. 18F-FDG was used as the PET tracer. The segmented ITVs from CT closely matched the expected motion for both no gating and gate 30–70 window, with disagreement of contoured ITV with respect to the expected volume not exceeding 13%. PET contours were seen to overestimate volumes in all the cases, up to more than 40%. Conclusion: 4DPET images of a novel 3D printed phantom designed to mimic different uptake values were obtained. 4DPET contours overestimated ITV volumes in all cases, while 4DCT contours matched expected ITV volume values. Investigation of the cause and effects of the discrepancies is undergoing.« less

A major upgrade of the sediment echosounder ATLAS PARASOUND and the digital acquisition software ParaDigMA for high-resolution sea floor studies

NASA Astrophysics Data System (ADS)

Gerriets, A.; von Lom-Keil, H.; Spiess, V.; Zwanzig, C.; Bruns, R.

2003-04-01

The combination of the ATLAS PARASOUND sediment echosounder, designed by ATLAS Hydrographic, and the digital recording software package ParaDigMA (commercially available as ATLAS PARASTORE-3) for online digitisation, preprocessing and visualisation of recorded seismograms has proven to be a reliable system for high-resolution acoustic sea floor studies. During 10 years of successful operation aboard several research vessels, including R/V Meteor, R/V Sonne and R/V Polarstern, the system has been only slightly modified. Based on this experience, today's PARASOUND/ParaDigMA system has accomplished the step from DOS towards Windows platform and network capability. In cooperation of ATLAS Hydrographic and the Department of Earth Sciences, University of Bremen a major upgrade of the PARASOUND/ParaDigMA system has been developed that adds significant functionality for surveys of sediment structures and sea floor morphology. The innovations primarily concern the control section of the ATLAS PARASOUND echosounder and the ParaDigMA user front end. The previous analogue PARASOUND control terminal has been replaced by a small real time control PC responsible for the control of the echosounder as well as for the continuous digitisation of the data. The control PC communicates via standard network protocols metadata and data with client applications that can display and store the acquired data on different computers on the network. The new network capabilities of the system overcome former limitations and admit a high flexibility with respect to numbers and locations of operator and recording/display PCs. The system now offers a simultaneous parallel registration of the 2.5-5.5kHz parametric signal and the 18kHz NBS signal. This feature in combination with the recording of complete soundings including the entire water column provides the basis for evolving scientific research topics e. g. gas venting. The ParaDigMA recording software now operates on Windows platforms which provide sophisticated possibilities in data visualisation as well as improved methods in data handling. Former approved features as online plot of the preprocessed seismograms have been continued.

Towards Continuity in Cloud Properties from MODIS and Suomi-NPP Polar-Orbiting Sensors

NASA Astrophysics Data System (ADS)

Baum, B. A.; Menzel, P.; Gladkova, I.; Heidinger, A. K.

2015-12-01

The intent of this talk is to discuss the progress and issues involved with developing a continuous record of cloud properties since 1978, beginning with the High Resolution Infrared Radiation Sounder (HIRS), then MODIS on the NASA Terra/Aqua platforms, and into the future from merged CrIS and VIIRS data. The MODIS measurements include infrared (IR) window radiances at 8.5-, 11- and 12-μm and four 15-μm channels in the broad CO2 absorption band. Cloud top pressure/height and emissivity are derived using a technique in which the strength is in retrievals for mid-to-high clouds but less so for low clouds where there is little thermal contrast with the surface. Additionally, MODIS provides a decadal IR cloud phase product. The goal now is to extend this continuity from HIRS and MODIS to the S-NPP era. However, there is one large drawback to consider: VIIRS has no infrared (IR) absorption channels. The lack of at least one IR absorption channel on VIIRS degrades the accuracy of the cloud properties. There is a solution: we can construct a 13.3-μm channel from a combination of VIIRS and CrIS (Cross-track Infrared Sounder). The approach involves using the high spatial resolution VIIRS IR window channels in combination with a lower spatial resolution 13.3-μm channel derived using CrIS high spectral resolution measurements. The result is a 13.3-μm pseudo-channel at the VIIRS pixel spatial resolution of 750 m (i.e., M-band resolution). The radiometric accuracy of this approach was tested using MODIS and AIRS, and found to be within 1-2%. The availability of the pseudo-channel increases the potential for achieving continuity between MODIS and S-NPP. Since future platforms will likely continue with a pairing of an imager and hyperspectral sounder, this work lays a foundation for future cloud product continuity. We will show how the use of this new channel will impact the cloud height and phase products.

OpenTopography: Addressing Big Data Challenges Using Cloud Computing, HPC, and Data Analytics

NASA Astrophysics Data System (ADS)

Crosby, C. J.; Nandigam, V.; Phan, M.; Youn, C.; Baru, C.; Arrowsmith, R.

2014-12-01

OpenTopography (OT) is a geoinformatics-based data facility initiated in 2009 for democratizing access to high-resolution topographic data, derived products, and tools. Hosted at the San Diego Supercomputer Center (SDSC), OT utilizes cyberinfrastructure, including large-scale data management, high-performance computing, and service-oriented architectures to provide efficient Web based access to large, high-resolution topographic datasets. OT collocates data with processing tools to enable users to quickly access custom data and derived products for their application. OT's ongoing R&D efforts aim to solve emerging technical challenges associated with exponential growth in data, higher order data products, as well as user base. Optimization of data management strategies can be informed by a comprehensive set of OT user access metrics that allows us to better understand usage patterns with respect to the data. By analyzing the spatiotemporal access patterns within the datasets, we can map areas of the data archive that are highly active (hot) versus the ones that are rarely accessed (cold). This enables us to architect a tiered storage environment consisting of high performance disk storage (SSD) for the hot areas and less expensive slower disk for the cold ones, thereby optimizing price to performance. From a compute perspective, OT is looking at cloud based solutions such as the Microsoft Azure platform to handle sudden increases in load. An OT virtual machine image in Microsoft's VM Depot can be invoked and deployed quickly in response to increased system demand. OT has also integrated SDSC HPC systems like the Gordon supercomputer into our infrastructure tier to enable compute intensive workloads like parallel computation of hydrologic routing on high resolution topography. This capability also allows OT to scale to HPC resources during high loads to meet user demand and provide more efficient processing. With a growing user base and maturing scientific user community comes new requests for algorithms and processing capabilities. To address this demand, OT is developing an extensible service based architecture for integrating community-developed software. This "plugable" approach to Web service deployment will enable new processing and analysis tools to run collocated with OT hosted data.

Dyes as bifunctional markers of DNA hybridization on surfaces and mutation detection.

PubMed

García-Mendiola, Tania; Cerro, María Ramos; López-Moreno, José María; Pariente, Félix; Lorenzo, Encarnación

2016-10-01

The interaction of small molecules with DNA has found diagnostic and therapeutic applications. In this work, we propose the use of two different dyes, in particular Azure A and Safranine, as bifunctional markers of on-surface DNA hybridization and potent tools for screening of specific gene mutations directly in real DNA PCR amplicons extracted from blood cells. By combining spectroscopic and electrochemical methods we demonstrate that both dyes can interact with single and double stranded DNA to a different extent, allowing reliable hybridization detection. From these data, we have also elucidated the nature of the interaction. We conclude that the binding mode is fundamentally intercalative with an electrostatic component. The dye fluorescence allows their use as nucleic acid stains for the detection of on-surfaces DNA hybridization. Its redox activity is exploited in the development of selective electrochemical DNA biosensors. Copyright © 2016 Elsevier B.V. All rights reserved.

Optical texture analysis for automatic cytology and histology: a Markovian approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pressman, N.J.

1976-10-12

Markovian analysis is a method to measure optical texture based on gray-level transition probabilities in digitized images. The experiments described in this dissertation investigate the classification performance of parameters generated by this method. Three types of data sets are used: images of (1) human blood leukocytes (nuclei of monocytes, neutrophils, and lymphocytes; Wright stain; (0.125 ..mu..m)/sup 2//picture point), (2) cervical exfoliative cells (nuclei of normal intermediate squamous cells and dysplastic and carcinoma in situ cells; azure-A/Feulgen stain; (0.125 ..mu..m)/sup 2//picture point), and (3) lymph-node tissue sections (6-..mu..m thick sections from normal, acute lymphadenitis, and Hodgkin lymph nodes; hematoxylin and eosinmore » stain; (0.625 ..mu..m)/sup 2/ picture point). Each image consists of 128 x 128 picture points originally scanned with a 256 gray-level resolution. Each image class is defined by 75 images.« less

The MATISSE analysis of large spectral datasets from the ESO Archive

NASA Astrophysics Data System (ADS)

Worley, C.; de Laverny, P.; Recio-Blanco, A.; Hill, V.; Vernisse, Y.; Ordenovic, C.; Bijaoui, A.

2010-12-01

The automated stellar classification algorithm, MATISSE, has been developed at the Observatoire de la Côte d'Azur (OCA) in order to determine stellar temperatures, gravities and chemical abundances for large datasets of stellar spectra. The Gaia Data Processing and Analysis Consortium (DPAC) has selected MATISSE as one of the key programmes to be used in the analysis of the Gaia Radial Velocity Spectrometer (RVS) spectra. MATISSE is currently being used to analyse large datasets of spectra from the ESO archive with the primary goal of producing advanced data products to be made available in the ESO database via the Virtual Observatory. This is also an invaluable opportunity to identify and address issues that can be encountered with the analysis large samples of real spectra prior to the launch of Gaia in 2012. The analysis of the archived spectra of the FEROS spectrograph is currently underway and preliminary results are presented.

Colloidal chitin stained with Remazol Brilliant Blue R, a useful substrate to select chitinolytic microorganisms and to evaluate chitinases.

PubMed

Gómez Ramírez, M; Rojas Avelizapa, L I; Rojas Avelizapa, N G; Cruz Camarillo, R

2004-02-01

A simple and sensitive method based on the use of colloidal chitin stained with Remazol Brilliant Blue R (RBB) is proposed to evaluate chitinase activity. If this colloidal-stained substrate is included as a carbon source in a liquid medium, this technique allows the selection or the comparison of chitinolytic microorganisms. The colloidal substrate is proportionally solubilized and the dye released is spectrophotometrically quantified at 595 nm. The procedures used for the staining and fixing of RBB in the colloidal chitin, and a comparison with the commercial substrate chitin-azure, are presented. The influence of several physicochemical and enzymatic parameters on the release of dyes is also shown. Both stained substrates were used for studying the effect of pH, substrate concentration, temperature and time on the chitinase reaction of Bacillus thuringiensis Bt-107.

SU-E-J-126: Respiratory Gating Quality Assurance: A Simple Method to Achieve Millisecond Temporal Resolution

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCabe, B; Wiersma, R

Purpose: Low temporal latency between a gating on/off signal and a linac beam on/off during respiratory gating is critical for patient safety. Although, a measurement of temporal lag is recommended by AAPM Task Group 142 for commissioning and annual quality assurance, there currently exists no published method. Here we describe a simple, inexpensive, and reliable method to precisely measure gating lag at millisecond resolutions. Methods: A Varian Real-time Position Management™ (RPM) gating simulator with rotating disk was modified with a resistive flex sensor (Spectra Symbol) attached to the gating box platform. A photon diode was placed at machine isocenter. Outputmore » signals of the flex sensor and diode were monitored with a multichannel oscilloscope (Tektronix™ DPO3014). Qualitative inspection of the gating window/beam on synchronicity were made by setting the linac to beam on/off at end-expiration, and the oscilloscope's temporal window to 100 ms to visually examine if the on/off timing was within the recommended 100-ms tolerance. Quantitative measurements were made by saving the signal traces and analyzing in MatLab™. The on and off of the beam signal were located and compared to the expected gating window (e.g. 40% to 60%). Four gating cycles were measured and compared. Results: On a Varian TrueBeam™ STx linac with RPM gating software, the average difference in synchronicity at beam on and off for four cycles was 14 ms (3 to 30 ms) and 11 ms (2 to 32 ms), respectively. For a Varian Clinac™ 21EX the average difference at beam on and off was 127 ms (122 to 133 ms) and 46 ms (42 to 49 ms), respectively. The uncertainty in the synchrony difference was estimated at ±6 ms. Conclusion: This new gating QA method is easy to implement and allows for fast qualitative inspection and quantitative measurements for commissioning and TG-142 annual QA measurements.« less

PET performance and MRI compatibility evaluation of a digital, ToF-capable PET/MRI insert equipped with clinical scintillators.

PubMed

Schug, David; Wehner, Jakob; Dueppenbecker, Peter Michael; Weissler, Bjoern; Gebhardt, Pierre; Goldschmidt, Benjamin; Salomon, Andre; Kiessling, Fabian; Schulz, Volkmar

2015-09-21

We evaluate the MR compatibility of the Hyperion-II(D) positron emission tomography (PET) insert, which allows simultaneous operation in a clinical magnetic resonance imaging (MRI) scanner. In contrast to previous investigations, this work aims at the evaluation of a clinical crystal configuration. An imaging-capable demonstrator with an axial field-of-view of 32 mm and a crystal-to-crystal spacing of 217.6 mm was equipped with LYSO scintillators with a pitch of 4 mm which were read out in a one-to-one coupling scheme by sensor tiles composed of digital silicon photomultipliers from Philips Digital Photon Counting (DPC 3200-22). The PET performance degradation (energy resolution and coincidence resolution time (CRT)) was evaluated during simultaneous operation of the MRI scanner. We used clinically motivated imaging sequences as well as synthetic gradient stress test sequences. Without activity of the MRI scanner, we measured for trigger scheme 1 (first photon trigger) an energy resolution of 11.4% and a CRT of 213 ps for a narrow energy (NE) window using five (22)Na point-like sources. When applying the synthetic gradient sequences, we found worst-case relative degradations of the energy resolution by 5.1% and of the CRT by 33.9%. After identifying the origin of the degradations and implementing a fix to the read-out hardware, the same evaluation revealed no degradation of the PET performance anymore even when the most demanding gradient stress tests were applied. The PET performance of the insert was initially evaluated using the point sources, a high-activity phantom and hot-rod phantoms in order to assess the spatial resolution. Trigger schemes 2-4 delivered an energy resolution of 11.4% as well and CRTs of 279 ps, 333 ps and 557 ps for the NE window, respectively. An isocenter sensitivity of 0.41% using the NE window and 0.71% with a wide energy window was measured. Using a hot-rod phantom, a spatial resolution in the order of 2 mm was demonstrated and the benefit of time-of-flight PET was shown with a larger rabbit-sized phantom. In conclusion, the Hyperion architecture is an interesting platform for clinically driven hybrid PET/MRI systems.

PET performance and MRI compatibility evaluation of a digital, ToF-capable PET/MRI insert equipped with clinical scintillators

NASA Astrophysics Data System (ADS)

Schug, David; Wehner, Jakob; Dueppenbecker, Peter Michael; Weissler, Bjoern; Gebhardt, Pierre; Goldschmidt, Benjamin; Salomon, Andre; Kiessling, Fabian; Schulz, Volkmar

2015-09-01

We evaluate the MR compatibility of the Hyperion-IID positron emission tomography (PET) insert, which allows simultaneous operation in a clinical magnetic resonance imaging (MRI) scanner. In contrast to previous investigations, this work aims at the evaluation of a clinical crystal configuration. An imaging-capable demonstrator with an axial field-of-view of 32 mm and a crystal-to-crystal spacing of 217.6 mm was equipped with LYSO scintillators with a pitch of 4 mm which were read out in a one-to-one coupling scheme by sensor tiles composed of digital silicon photomultipliers from Philips Digital Photon Counting (DPC 3200-22). The PET performance degradation (energy resolution and coincidence resolution time (CRT)) was evaluated during simultaneous operation of the MRI scanner. We used clinically motivated imaging sequences as well as synthetic gradient stress test sequences. Without activity of the MRI scanner, we measured for trigger scheme 1 (first photon trigger) an energy resolution of 11.4% and a CRT of 213 ps for a narrow energy (NE) window using five 22Na point-like sources. When applying the synthetic gradient sequences, we found worst-case relative degradations of the energy resolution by 5.1% and of the CRT by 33.9%. After identifying the origin of the degradations and implementing a fix to the read-out hardware, the same evaluation revealed no degradation of the PET performance anymore even when the most demanding gradient stress tests were applied. The PET performance of the insert was initially evaluated using the point sources, a high-activity phantom and hot-rod phantoms in order to assess the spatial resolution. Trigger schemes 2-4 delivered an energy resolution of 11.4% as well and CRTs of 279 ps, 333 ps and 557 ps for the NE window, respectively. An isocenter sensitivity of 0.41% using the NE window and 0.71% with a wide energy window was measured. Using a hot-rod phantom, a spatial resolution in the order of 2 mm was demonstrated and the benefit of time-of-flight PET was shown with a larger rabbit-sized phantom. In conclusion, the Hyperion architecture is an interesting platform for clinically driven hybrid PET/MRI systems.

BioNetFit: a fitting tool compatible with BioNetGen, NFsim and distributed computing environments

PubMed Central

Thomas, Brandon R.; Chylek, Lily A.; Colvin, Joshua; Sirimulla, Suman; Clayton, Andrew H.A.; Hlavacek, William S.; Posner, Richard G.

2016-01-01

Summary: Rule-based models are analyzed with specialized simulators, such as those provided by the BioNetGen and NFsim open-source software packages. Here, we present BioNetFit, a general-purpose fitting tool that is compatible with BioNetGen and NFsim. BioNetFit is designed to take advantage of distributed computing resources. This feature facilitates fitting (i.e. optimization of parameter values for consistency with data) when simulations are computationally expensive. Availability and implementation: BioNetFit can be used on stand-alone Mac, Windows/Cygwin, and Linux platforms and on Linux-based clusters running SLURM, Torque/PBS, or SGE. The BioNetFit source code (Perl) is freely available (http://bionetfit.nau.edu). Supplementary information: Supplementary data are available at Bioinformatics online. Contact: bionetgen.help@gmail.com PMID:26556387

Mask data processing in the era of multibeam writers

NASA Astrophysics Data System (ADS)

Abboud, Frank E.; Asturias, Michael; Chandramouli, Maesh; Tezuka, Yoshihiro

2014-10-01

Mask writers' architectures have evolved through the years in response to ever tightening requirements for better resolution, tighter feature placement, improved CD control, and tolerable write time. The unprecedented extension of optical lithography and the myriad of Resolution Enhancement Techniques have tasked current mask writers with ever increasing shot count and higher dose, and therefore, increasing write time. Once again, we see the need for a transition to a new type of mask writer based on massively parallel architecture. These platforms offer a step function improvement in both dose and the ability to process massive amounts of data. The higher dose and almost unlimited appetite for edge corrections open new windows of opportunity to further push the envelope. These architectures are also naturally capable of producing curvilinear shapes, making the need to approximate a curve with multiple Manhattan shapes unnecessary.

libdrdc: software standards library

NASA Astrophysics Data System (ADS)

Erickson, David; Peng, Tie

2008-04-01

This paper presents the libdrdc software standards library including internal nomenclature, definitions, units of measure, coordinate reference frames, and representations for use in autonomous systems research. This library is a configurable, portable C-function wrapped C++ / Object Oriented C library developed to be independent of software middleware, system architecture, processor, or operating system. It is designed to use the automatically-tuned linear algebra suite (ATLAS) and Basic Linear Algebra Suite (BLAS) and port to firmware and software. The library goal is to unify data collection and representation for various microcontrollers and Central Processing Unit (CPU) cores and to provide a common Application Binary Interface (ABI) for research projects at all scales. The library supports multi-platform development and currently works on Windows, Unix, GNU/Linux, and Real-Time Executive for Multiprocessor Systems (RTEMS). This library is made available under LGPL version 2.1 license.

Overview of GSE as a multifunctional GUI

NASA Astrophysics Data System (ADS)

Kurtovich, Boyan; Malangone, Fabio; Voss, David L.; Carssow, Douglas B.; Fritz, Theodore A.; Mavretic, Anton

2009-08-01

Ground Support Equipment (GSE) [1] is a versatile and multifunctional graphical user interface (GUI) and a software/hardware platform. It is a custom-designed system executed in the LabVIEW programming language to serve as an instrument health monitor for the Loss Cone Imager (LCI) satellite project. GSE mimics the behavior of the onboard Experiment Computer System (ECS). Its functions comprise the measurement of voltage, current, and power, as well as acting as a safety mechanism in case of any anomalous condition (e.g., over-current and/or over-voltage situation). Individual log files record the sessions during which data is gathered and analyzed. Safety/warning alarm flags shall be 'visible' from any individual window/tab. Analog-to-Digital Conversion (ADC) particle group measurements will be displayed on six individual panels. GSE will be supplemented with a comprehensive user's manual for added clarity.

Simulated Thin-Film Growth and Imaging

NASA Astrophysics Data System (ADS)

Schillaci, Michael

2001-06-01

Thin-films have become the cornerstone of the electronics, telecommunications, and broadband markets. A list of potential products includes: computer boards and chips, satellites, cell phones, fuel cells, superconductors, flat panel displays, optical waveguides, building and automotive windows, food and beverage plastic containers, metal foils, pipe plating, vision ware, manufacturing equipment and turbine engines. For all of these reasons a basic understanding of the physical processes involved in both growing and imaging thin-films can provide a wonderful research project for advanced undergraduate and first-year graduate students. After producing rudimentary two- and three-dimensional thin-film models incorporating ballsitic deposition and nearest neighbor Coulomb-type interactions, the QM tunneling equations are used to produce simulated scanning tunneling microscope (SSTM) images of the films. A discussion of computational platforms, languages, and software packages that may be used to accomplish similar results is also given.

Ionic Liquid-Based Optical and Electrochemical Carbon Dioxide Sensors.

PubMed

Behera, Kamalakanta; Pandey, Shubha; Kadyan, Anu; Pandey, Siddharth

2015-12-04

Due to their unusual physicochemical properties (e.g., high thermal stability, low volatility, high intrinsic conductivity, wide electrochemical windows and good solvating ability), ionic liquids have shown immense application potential in many research areas. Applications of ionic liquid in developing various sensors, especially for the sensing of biomolecules, such as nucleic acids, proteins and enzymes, gas sensing and sensing of various important ions, among other chemosensing platforms, are currently being explored by researchers worldwide. The use of ionic liquids for the detection of carbon dioxide (CO₂) gas is currently a major topic of research due to the associated importance of this gas with daily human life. This review focuses on the application of ionic liquids in optical and electrochemical CO₂ sensors. The design, mechanism, sensitivity and detection limit of each type of sensor are highlighted in this review.

Stochastic Inversion of 2D Magnetotelluric Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Jinsong

2010-07-01

The algorithm is developed to invert 2D magnetotelluric (MT) data based on sharp boundary parametrization using a Bayesian framework. Within the algorithm, we consider the locations and the resistivity of regions formed by the interfaces are as unknowns. We use a parallel, adaptive finite-element algorithm to forward simulate frequency-domain MT responses of 2D conductivity structure. Those unknown parameters are spatially correlated and are described by a geostatistical model. The joint posterior probability distribution function is explored by Markov Chain Monte Carlo (MCMC) sampling methods. The developed stochastic model is effective for estimating the interface locations and resistivity. Most importantly, itmore » provides details uncertainty information on each unknown parameter. Hardware requirements: PC, Supercomputer, Multi-platform, Workstation; Software requirements C and Fortan; Operation Systems/version is Linux/Unix or Windows« less

Parity-time-symmetry enhanced optomechanically-induced-transparency

PubMed Central

Li, Wenlin; Jiang, Yunfeng; Li, Chong; Song, Heshan

2016-01-01

We propose and analyze a scheme to enhance optomechanically-induced-transparency (OMIT) based on parity-time-symmetric optomechanical system. Our results predict that an OMIT window which does not exist originally can appear in weak optomechanical coupling and driving system via coupling an auxiliary active cavity with optical gain. This phenomenon is quite different from these reported in previous works in which the gain is considered just to damage OMIT phenomenon even leads to electromagnetically induced absorption or inverted-OMIT. Such enhanced OMIT effects are ascribed to the additional gain which can increase photon number in cavity without reducing effective decay. We also discuss the scheme feasibility by analyzing recent experiment parameters. Our work provide a promising platform for the coherent manipulation and slow light operation, which has potential applications for quantum information processing and quantum optical device. PMID:27489193

KSC-05PD-1177

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. At NASAs Kennedy Space Center, Space Shuttle Discovery, resting on the Mobile Launcher Platform, rolls into high bay 1 of the Vehicle Assembly Building (VAB). The Shuttle is being rolled back from Launch Pad 39B. It will be demated from its External Tank and lifted into the transfer aisle. On or about June 7, Discovery will be attached to its new tank and Solid Rocket Boosters, which are already in the VAB. Only the 15th rollback in Space Shuttle Program history, the 4.2- mile journey allows additional modifications to be made to the External Tank prior to a safe Return to Flight. Discovery is expected to be rolled back to the launch pad in mid-June for Return to Flight mission STS-114. The launch window extends from July 13 to July 31. [Photo courtesy of Scott Andrews

A Multidisciplinary Tool for Systems Analysis of Planetary Entry, Descent, and Landing (SAPE)

NASA Technical Reports Server (NTRS)

Samareh, Jamshid A.

2009-01-01

SAPE is a Python-based multidisciplinary analysis tool for systems analysis of planetary entry, descent, and landing (EDL) for Venus, Earth, Mars, Jupiter, Saturn, Uranus, Neptune, and Titan. The purpose of SAPE is to provide a variable-fidelity capability for conceptual and preliminary analysis within the same framework. SAPE includes the following analysis modules: geometry, trajectory, aerodynamics, aerothermal, thermal protection system, and structural sizing. SAPE uses the Python language-a platform-independent open-source software for integration and for the user interface. The development has relied heavily on the object-oriented programming capabilities that are available in Python. Modules are provided to interface with commercial and government off-the-shelf software components (e.g., thermal protection systems and finite-element analysis). SAPE runs on Microsoft Windows and Apple Mac OS X and has been partially tested on Linux.

KSC-05PD-1659

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. In the transfer aisle of the Vehicle Assembly Building at NASA Kennedy Space Center, In the transfer aisle of the Vehicle Assembly Building at NASA Kennedy Space Center, orbiter technicians are hooking a restraining cable around the orbiter lifting slings aft drop leg adjustment hand wheel. This is performed prior to disconnecting the aft spreader beam from the sling (the portion suspended by the 175 ton crane on the left side of the photo), and also prior to taking the final hang angle measurement of the orbiter prior to lifting it over the transom into the high bay. It will be mated with the Solid Rocket Boosters and External Tank already stacked there on the Mobile Launcher Platform. Atlantis is the designated orbiter for Return to Flight mission STS-121. The lighted planning window for launch extends from Sept. 9 to Sept. 25.

KSC-05PD-1660

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. In the transfer aisle of the Vehicle Assembly Building at NASA Kennedy Space Center, In the transfer aisle of the Vehicle Assembly Building at NASA Kennedy Space Center, orbiter technicians are hooking a restraining cable around the orbiter lifting slings aft drop leg adjustment hand wheel. This is performed prior to disconnecting the aft spreader beam from the sling (the portion suspended by the 175 ton crane on the left side of the photo), and also prior to taking the final hang angle measurement of the orbiter prior to lifting it over the transom into the high bay. It will be mated with the Solid Rocket Boosters and External Tank already stacked there on the Mobile Launcher Platform. Atlantis is the designated orbiter for Return to Flight mission STS-121. The lighted planning window for launch extends from Sept. 9 to Sept. 25.

High-Performance Supercapacitor Electrode Based on Cobalt Oxide-Manganese Dioxide-Nickel Oxide Ternary 1D Hybrid Nanotubes.

PubMed

Singh, Ashutosh K; Sarkar, Debasish; Karmakar, Keshab; Mandal, Kalyan; Khan, Gobinda Gopal

2016-08-17

We report a facile method to design Co3O4-MnO2-NiO ternary hybrid 1D nanotube arrays for their application as active material for high-performance supercapacitor electrodes. This as-prepared novel supercapacitor electrode can store charge as high as ∼2020 C/g (equivalent specific capacitance ∼2525 F/g) for a potential window of 0.8 V and has long cycle stability (nearly 80% specific capacitance retains after successive 5700 charge/discharge cycles), significantly high Coulombic efficiency, and fast response time (∼0.17s). The remarkable electrochemical performance of this unique electrode material is the outcome of its enormous reaction platform provided by its special nanostructure morphology and conglomeration of the electrochemical properties of three highly redox active materials in a single unit.

A user's guide to Sandia's latin hypercube sampling software : LHS UNIX library/standalone version.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swiler, Laura Painton; Wyss, Gregory Dane

2004-07-01

This document is a reference guide for the UNIX Library/Standalone version of the Latin Hypercube Sampling Software. This software has been developed to generate Latin hypercube multivariate samples. This version runs on Linux or UNIX platforms. This manual covers the use of the LHS code in a UNIX environment, run either as a standalone program or as a callable library. The underlying code in the UNIX Library/Standalone version of LHS is almost identical to the updated Windows version of LHS released in 1998 (SAND98-0210). However, some modifications were made to customize it for a UNIX environment and as a librarymore » that is called from the DAKOTA environment. This manual covers the use of the LHS code as a library and in the standalone mode under UNIX.« less

DELIMINATE--a fast and efficient method for loss-less compression of genomic sequences: sequence analysis.

PubMed

Mohammed, Monzoorul Haque; Dutta, Anirban; Bose, Tungadri; Chadaram, Sudha; Mande, Sharmila S

2012-10-01

An unprecedented quantity of genome sequence data is currently being generated using next-generation sequencing platforms. This has necessitated the development of novel bioinformatics approaches and algorithms that not only facilitate a meaningful analysis of these data but also aid in efficient compression, storage, retrieval and transmission of huge volumes of the generated data. We present a novel compression algorithm (DELIMINATE) that can rapidly compress genomic sequence data in a loss-less fashion. Validation results indicate relatively higher compression efficiency of DELIMINATE when compared with popular general purpose compression algorithms, namely, gzip, bzip2 and lzma. Linux, Windows and Mac implementations (both 32 and 64-bit) of DELIMINATE are freely available for download at: http://metagenomics.atc.tcs.com/compression/DELIMINATE. sharmila@atc.tcs.com Supplementary data are available at Bioinformatics online.

CERNBox + EOS: end-user storage for science

NASA Astrophysics Data System (ADS)

Mascetti, L.; Gonzalez Labrador, H.; Lamanna, M.; Mościcki, JT; Peters, AJ

2015-12-01

CERNBox is a cloud synchronisation service for end-users: it allows syncing and sharing files on all major mobile and desktop platforms (Linux, Windows, MacOSX, Android, iOS) aiming to provide offline availability to any data stored in the CERN EOS infrastructure. The successful beta phase of the service confirmed the high demand in the community for an easily accessible cloud storage solution such as CERNBox. Integration of the CERNBox service with the EOS storage back-end is the next step towards providing “sync and share” capabilities for scientific and engineering use-cases. In this report we will present lessons learnt in offering the CERNBox service, key technical aspects of CERNBox/EOS integration and new, emerging usage possibilities. The latter includes the ongoing integration of “sync and share” capabilities with the LHC data analysis tools and transfer services.

[The RUTA project (Registro UTIC Triveneto ANMCO). An e-network for the coronary care units for acute myocardial infarction].

PubMed

Di Chiara, Antonio; Zonzin, Pietro; Pavoni, Daisy; Fioretti, Paolo Maria

2003-06-01

In the era of evidence-based medicine, the monitoring of the adherence to the guidelines is fundamental, in order to verify the diagnostic and therapeutic processes. Informatic paperless databases allow a higher data quality, lower costs and timely analysis with overall advantages over the traditional surveys. The RUTA project (acronym of Triveneto Registry of ANMCO CCUs) was designed in 1999, aiming at creating an informatic network among the coronary care units of a large Italian region, for a permanent survey of patients admitted for acute myocardial infarction. Information ranges from the pre-hospital phase to discharge, including all relevant clinical and management variables. The database uses DBMS Personal Oracle and Power-Builder as user interface, on Windows platform. Anonymous data are sent to a central server.

Source Lines Counter (SLiC) Version 4.0

NASA Technical Reports Server (NTRS)

Monson, Erik W.; Smith, Kevin A.; Newport, Brian J.; Gostelow, Roli D.; Hihn, Jairus M.; Kandt, Ronald K.

2011-01-01

Source Lines Counter (SLiC) is a software utility designed to measure software source code size using logical source statements and other common measures for 22 of the programming languages commonly used at NASA and the aerospace industry. Such metrics can be used in a wide variety of applications, from parametric cost estimation to software defect analysis. SLiC has a variety of unique features such as automatic code search, automatic file detection, hierarchical directory totals, and spreadsheet-compatible output. SLiC was written for extensibility; new programming language support can be added with minimal effort in a short amount of time. SLiC runs on a variety of platforms including UNIX, Windows, and Mac OSX. Its straightforward command-line interface allows for customization and incorporation into the software build process for tracking development metrics. T

Advancing Science Literacy Through the Climate Change National Forum

NASA Astrophysics Data System (ADS)

Nielsen-Gammon, J. W.; Quirke, M.; Lefer, B. L.; Hester, T.

2014-12-01

The Climate Change National Forum (http://climatechangenationalforum.org) was established almost a year ago to provide a publicly visible platform for discussion of scientific issues related to climate change and, at a later date, policy options motivated by climate change science. The site is also designed to promote public literacy in the culture and conduct of science by incorporating dozens of active scientists in a broad range of climate science and related fields and encouraging dialogue among those scientists. The forum provides a rare window into scientific debate, allowing non-scientists to see how scientists evaluate the work of others, construct meaning out of various bits of evidence, formulate ideas, challenge their colleagues, and (on occasion) develop a consensus. As such, the site is intended to have educational value well beyond its climate science focus.

The General Mission Analysis Tool (GMAT): Current Features And Adding Custom Functionality

NASA Technical Reports Server (NTRS)

Conway, Darrel J.; Hughes, Steven P.

2010-01-01

The General Mission Analysis Tool (GMAT) is a software system for trajectory optimization, mission analysis, trajectory estimation, and prediction developed by NASA, the Air Force Research Lab, and private industry. GMAT's design and implementation are based on four basic principles: open source visibility for both the source code and design documentation; platform independence; modular design; and user extensibility. The system, released under the NASA Open Source Agreement, runs on Windows, Mac and Linux. User extensions, loaded at run time, have been built for optimization, trajectory visualization, force model extension, and estimation, by parties outside of GMAT's development group. The system has been used to optimize maneuvers for the Lunar Crater Observation and Sensing Satellite (LCROSS) and ARTEMIS missions and is being used for formation design and analysis for the Magnetospheric Multiscale Mission (MMS).

Ionic Liquid-Based Optical and Electrochemical Carbon Dioxide Sensors

PubMed Central

Behera, Kamalakanta; Pandey, Shubha; Kadyan, Anu; Pandey, Siddharth

2015-01-01

Due to their unusual physicochemical properties (e.g., high thermal stability, low volatility, high intrinsic conductivity, wide electrochemical windows and good solvating ability), ionic liquids have shown immense application potential in many research areas. Applications of ionic liquid in developing various sensors, especially for the sensing of biomolecules, such as nucleic acids, proteins and enzymes, gas sensing and sensing of various important ions, among other chemosensing platforms, are currently being explored by researchers worldwide. The use of ionic liquids for the detection of carbon dioxide (CO2) gas is currently a major topic of research due to the associated importance of this gas with daily human life. This review focuses on the application of ionic liquids in optical and electrochemical CO2 sensors. The design, mechanism, sensitivity and detection limit of each type of sensor are highlighted in this review. PMID:26690155

ABMapper: a suffix array-based tool for multi-location searching and splice-junction mapping.

PubMed

Lou, Shao-Ke; Ni, Bing; Lo, Leung-Yau; Tsui, Stephen Kwok-Wing; Chan, Ting-Fung; Leung, Kwong-Sak

2011-02-01

Sequencing reads generated by RNA-sequencing (RNA-seq) must first be mapped back to the genome through alignment before they can be further analyzed. Current fast and memory-saving short-read mappers could give us a quick view of the transcriptome. However, they are neither designed for reads that span across splice junctions nor for repetitive reads, which can be mapped to multiple locations in the genome (multi-reads). Here, we describe a new software package: ABMapper, which is specifically designed for exploring all putative locations of reads that are mapped to splice junctions or repetitive in nature. The software is freely available at: http://abmapper.sourceforge.net/. The software is written in C++ and PERL. It runs on all major platforms and operating systems including Windows, Mac OS X and LINUX.

SHIELDING CONSIDERATIONS FOR THE SMALL ANIMAL RADIATION RESEARCH PLATFORM (SARRP)

PubMed Central

Sayler, Elaine; Dolney, Derek; Avery, Stephen; Koch, Cameron

2014-01-01

The Small Animal Radiation Research Platform (SARRP) is a commercially available platform designed to deliver conformal, image-guided radiation to small animals using a dual-anode kV x-ray source. At the University of Pennsylvania, a free-standing 2 m3 enclosure was designed to shield the SARRP according to federal code regulating cabinet x-ray systems. The initial design consisted of 4.0-mm-thick lead for all secondary barriers and proved wholly inadequate. Radiation levels outside the enclosure were 15 times higher than expected. Additionally, the leakage appeared to be distributed broadly within the enclosure, so concern arose that a subject might receive significant doses outside the intended treatment field. Thus, a detailed analysis was undertaken to identify and block all sources of leakage. Leakage sources were identified by Kodak X-OmatV (XV) film placed throughout the enclosure. Radiation inside the enclosure was quantified using Gafchromic film. Outside the enclosure, radiation was measured using a survey meter. Sources of leakage included (1) an unnecessarily broad beam exiting the tube, (2) failure of the secondary collimator to confine the primary beam entirely, (3) scatter from the secondary collimator, (4) lack of beam-stop below the treatment volume, and (5) incomplete shielding of the x-ray tube. The exit window was restricted, and a new collimator was designed to address problems (1–3). A beam-stop and additional tube shielding were installed. These modifications reduced internal scatter by more than 100-fold. Radiation outside the enclosure was reduced to levels compliant with federal regulations, provided the SARRP is operated using tube potentials of 175 kV or less. In addition, these simple and relatively inexpensive modifications eliminate the possibility of exposing a larger animal (such as a rat) to significant doses outside the treatment field. PMID:23532076

DataViewer3D: An Open-Source, Cross-Platform Multi-Modal Neuroimaging Data Visualization Tool

PubMed Central

Gouws, André; Woods, Will; Millman, Rebecca; Morland, Antony; Green, Gary

2008-01-01

Integration and display of results from multiple neuroimaging modalities [e.g. magnetic resonance imaging (MRI), magnetoencephalography, EEG] relies on display of a diverse range of data within a common, defined coordinate frame. DataViewer3D (DV3D) is a multi-modal imaging data visualization tool offering a cross-platform, open-source solution to simultaneous data overlay visualization requirements of imaging studies. While DV3D is primarily a visualization tool, the package allows an analysis approach where results from one imaging modality can guide comparative analysis of another modality in a single coordinate space. DV3D is built on Python, a dynamic object-oriented programming language with support for integration of modular toolkits, and development of cross-platform software for neuroimaging. DV3D harnesses the power of the Visualization Toolkit (VTK) for two-dimensional (2D) and 3D rendering, calling VTK's low level C++ functions from Python. Users interact with data via an intuitive interface that uses Python to bind wxWidgets, which in turn calls the user's operating system dialogs and graphical user interface tools. DV3D currently supports NIfTI-1, ANALYZE™ and DICOM formats for MRI data display (including statistical data overlay). Formats for other data types are supported. The modularity of DV3D and ease of use of Python allows rapid integration of additional format support and user development. DV3D has been tested on Mac OSX, RedHat Linux and Microsoft Windows XP. DV3D is offered for free download with an extensive set of tutorial resources and example data. PMID:19352444

Identifier mapping performance for integrating transcriptomics and proteomics experimental results

PubMed Central

2011-01-01

Background Studies integrating transcriptomic data with proteomic data can illuminate the proteome more clearly than either separately. Integromic studies can deepen understanding of the dynamic complex regulatory relationship between the transcriptome and the proteome. Integrating these data dictates a reliable mapping between the identifier nomenclature resultant from the two high-throughput platforms. However, this kind of analysis is well known to be hampered by lack of standardization of identifier nomenclature among proteins, genes, and microarray probe sets. Therefore data integration may also play a role in critiquing the fallible gene identifications that both platforms emit. Results We compared three freely available internet-based identifier mapping resources for mapping UniProt accessions (ACCs) to Affymetrix probesets identifications (IDs): DAVID, EnVision, and NetAffx. Liquid chromatography-tandem mass spectrometry analyses of 91 endometrial cancer and 7 noncancer samples generated 11,879 distinct ACCs. For each ACC, we compared the retrieval sets of probeset IDs from each mapping resource. We confirmed a high level of discrepancy among the mapping resources. On the same samples, mRNA expression was available. Therefore, to evaluate the quality of each ACC-to-probeset match, we calculated proteome-transcriptome correlations, and compared the resources presuming that better mapping of identifiers should generate a higher proportion of mapped pairs with strong inter-platform correlations. A mixture model for the correlations fitted well and supported regression analysis, providing a window into the performance of the mapping resources. The resources have added and dropped matches over two years, but their overall performance has not changed. Conclusions The methods presented here serve to achieve concrete context-specific insight, to support well-informed decisions in choosing an ID mapping strategy for "omic" data merging. PMID:21619611

The Transcriptome Analysis and Comparison Explorer--T-ACE: a platform-independent, graphical tool to process large RNAseq datasets of non-model organisms.

PubMed

Philipp, E E R; Kraemer, L; Mountfort, D; Schilhabel, M; Schreiber, S; Rosenstiel, P

2012-03-15

Next generation sequencing (NGS) technologies allow a rapid and cost-effective compilation of large RNA sequence datasets in model and non-model organisms. However, the storage and analysis of transcriptome information from different NGS platforms is still a significant bottleneck, leading to a delay in data dissemination and subsequent biological understanding. Especially database interfaces with transcriptome analysis modules going beyond mere read counts are missing. Here, we present the Transcriptome Analysis and Comparison Explorer (T-ACE), a tool designed for the organization and analysis of large sequence datasets, and especially suited for transcriptome projects of non-model organisms with little or no a priori sequence information. T-ACE offers a TCL-based interface, which accesses a PostgreSQL database via a php-script. Within T-ACE, information belonging to single sequences or contigs, such as annotation or read coverage, is linked to the respective sequence and immediately accessible. Sequences and assigned information can be searched via keyword- or BLAST-search. Additionally, T-ACE provides within and between transcriptome analysis modules on the level of expression, GO terms, KEGG pathways and protein domains. Results are visualized and can be easily exported for external analysis. We developed T-ACE for laboratory environments, which have only a limited amount of bioinformatics support, and for collaborative projects in which different partners work on the same dataset from different locations or platforms (Windows/Linux/MacOS). For laboratories with some experience in bioinformatics and programming, the low complexity of the database structure and open-source code provides a framework that can be customized according to the different needs of the user and transcriptome project.

Engaging older adults in the visualization of sensor data facilitated by an open platform for connected devices.

PubMed

Bock, Christian; Demiris, George; Choi, Yong; Le, Thai; Thompson, Hilaire J; Samuel, Arjmand; Huang, Danny

2016-03-11

The use of smart home sensor systems is growing primarily due to the appeal of unobtrusively monitoring older adult health and wellness. However, integrating large-scale sensor systems within residential settings can be challenging when deployment takes place across multiple environments, requiring customization of applications, connection across various devices and effective visualization of complex longitudinal data. The objective of the study was to demonstrate the implementation of a smart home system using an open, extensible platform in a real-world setting and develop an application to visualize data real time. We deployed the open source Lab of Things platform in a house of 11 residents as a demonstration of feasibility over the course of 3 months. The system consisted of Aeon Labs Z-wave Door/Window sensors and an Aeon Labs Multi-sensor that collected data on motion, temperature, luminosity, and humidity. We applied a Rapid Iterative Testing and Evaluation approach towards designing a visualization interface engaging gerontological experts. We then conducted a survey with 19 older adult and caregiver stakeholders to inform further design revisions. Our initial visualization mockups consisted of a bar chart representing activity level over time. Family members felt comfortable using the application. Older adults however, indicated it would be difficult to learn to use the application, and had trouble identifying utility. A key for older adults was ensuring that the data collected could be utilized by their family members, physicians, or caregivers. The approach described in this work is generalizable towards future smart home deployments and can be a valuable guide for researchers to scale a study across multiple homes and connected devices, and to create personalized interfaces for end users.

Xyce Parallel Electronic Simulator Users Guide Version 6.2.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keiter, Eric R.; Mei, Ting; Russo, Thomas V.

This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been de- signed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: Capability to solve extremely large circuit problems by supporting large-scale parallel com- puting platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows onemore » to develop new types of analysis without requiring the implementation of analysis-specific device models. Device models that are specifically tailored to meet Sandia's needs, including some radiation- aware devices (for Sandia users only). Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase -- a message passing parallel implementation -- which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows. Trademarks The information herein is subject to change without notice. Copyright c 2002-2014 Sandia Corporation. All rights reserved. Xyce TM Electronic Simulator and Xyce TM are trademarks of Sandia Corporation. Portions of the Xyce TM code are: Copyright c 2002, The Regents of the University of California. Produced at the Lawrence Livermore National Laboratory. Written by Alan Hindmarsh, Allan Taylor, Radu Serban. UCRL-CODE-2002-59 All rights reserved. Orcad, Orcad Capture, PSpice and Probe are registered trademarks of Cadence Design Systems, Inc. Microsoft, Windows and Windows 7 are registered trademarks of Microsoft Corporation. Medici, DaVinci and Taurus are registered trademarks of Synopsys Corporation. Amtec and TecPlot are trademarks of Amtec Engineering, Inc. Xyce 's expression library is based on that inside Spice 3F5 developed by the EECS Department at the University of California. The EKV3 MOSFET model was developed by the EKV Team of the Electronics Laboratory-TUC of the Technical University of Crete. All other trademarks are property of their respective owners. Contacts Bug Reports (Sandia only) http://joseki.sandia.gov/bugzilla http://charleston.sandia.gov/bugzilla World Wide Web http://xyce.sandia.gov http://charleston.sandia.gov/xyce (Sandia only) Email xyce@sandia.gov (outside Sandia) xyce-sandia@sandia.gov (Sandia only)« less

Xyce Parallel Electronic Simulator Users Guide Version 6.4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keiter, Eric R.; Mei, Ting; Russo, Thomas V.

This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been de- signed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: Capability to solve extremely large circuit problems by supporting large-scale parallel com- puting platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows onemore » to develop new types of analysis without requiring the implementation of analysis-specific device models. Device models that are specifically tailored to meet Sandia's needs, including some radiation- aware devices (for Sandia users only). Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase -- a message passing parallel implementation -- which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows. Trademarks The information herein is subject to change without notice. Copyright c 2002-2015 Sandia Corporation. All rights reserved. Xyce TM Electronic Simulator and Xyce TM are trademarks of Sandia Corporation. Portions of the Xyce TM code are: Copyright c 2002, The Regents of the University of California. Produced at the Lawrence Livermore National Laboratory. Written by Alan Hindmarsh, Allan Taylor, Radu Serban. UCRL-CODE-2002-59 All rights reserved. Orcad, Orcad Capture, PSpice and Probe are registered trademarks of Cadence Design Systems, Inc. Microsoft, Windows and Windows 7 are registered trademarks of Microsoft Corporation. Medici, DaVinci and Taurus are registered trademarks of Synopsys Corporation. Amtec and TecPlot are trademarks of Amtec Engineering, Inc. Xyce 's expression library is based on that inside Spice 3F5 developed by the EECS Department at the University of California. The EKV3 MOSFET model was developed by the EKV Team of the Electronics Laboratory-TUC of the Technical University of Crete. All other trademarks are property of their respective owners. Contacts Bug Reports (Sandia only) http://joseki.sandia.gov/bugzilla http://charleston.sandia.gov/bugzilla World Wide Web http://xyce.sandia.gov http://charleston.sandia.gov/xyce (Sandia only) Email xyce@sandia.gov (outside Sandia) xyce-sandia@sandia.gov (Sandia only)« less

Understanding Windows | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Benefits of Efficient Windows | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Windows for New Construction | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Performance Standards for Windows | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Window Selection Tool | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Assessing Window Replacement Options | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Selection Process for New Windows | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Design Guidance for New Windows | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Selection Process for Replacement Windows | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards