DETERMINING THE MINIMUM NUMBER OF SITES FOR BIOASSESSMENT OF THE OHIO RIVER

EPA Science Inventory

For wadeable stream bioassessment, much work has been done to determine the number of samples to composite or the appropriate reach length for obtaining an adequate sample. Proportions of stream miles in a given condition are then often reported at the watershed or ecoregion lev...

A new methodological approach to assess cardiac work by pressure-volume and stress-length relations in patients with aortic valve stenosis and dilated cardiomyopathy.

PubMed

Alter, P; Rupp, H; Rominger, M B; Klose, K J; Maisch, B

2008-01-01

In experimental animals, cardiac work is derived from pressure-volume area and analyzed further using stress-length relations. Lack of methods for determining accurately myocardial mass has until now prevented the use of stress-length relations in patients. We hypothesized, therefore, that not only pressure-volume loops but also stress-length diagrams can be derived from cardiac volume and cardiac mass as assessed by cardiac magnetic resonance imaging (CMR) and invasively measured pressure. Left ventricular (LV) volume and myocardial mass were assessed in seven patients with aortic valve stenosis (AS), eight with dilated cardiomyopathy (DCM), and eight controls using electrocardiogram (ECG)-gated CMR. LV pressure was measured invasively. Pressure-volume curves were calculated based on ECG triggering. Stroke work was assessed as area within the pressure-volume loop. LV wall stress was calculated using a thick-wall sphere model. Similarly, stress-length loops were calculated to quantify stress-length-based work. Taking the LV geometry into account, the normalization with regard to ventricular circumference resulted in "myocardial work." Patients with AS (valve area 0.73+/-0.18 cm(2)) exhibited an increased LV myocardial mass when compared with controls (P<0.05). LV wall stress was increased in DCM but not in AS. Stroke work of AS was unchanged when compared with controls (0.539+/-0.272 vs 0.621+/-0.138 Nm, not significant), whereas DCM exhibited a significant depression (0.367+/-0.157 Nm, P<0.05). Myocardial work was significantly reduced in both AS and DCM when compared with controls (129.8+/-69.6, 200.6+/-80.1, 332.2+/-89.6 Nm/m(2), P<0.05), also after normalization (7.40+/-5.07, 6.27+/-3.20, 14.6+/-4.07 Nm/m(2), P<0.001). It is feasible to obtain LV pressure-volume and stress-length diagrams in patients based on the present novel methodological approach of using CMR and invasive pressure measurement. Myocardial work was reduced in patients with DCM and noteworthy also in AS, while stroke work was reduced in DCM only. Most likely, deterioration of myocardial work is crucial for the prognosis. It is suggested to include these basic physiological procedures in the clinical assessment of the pump function of the heart.

Working conditions of nurses and absenteeism: is there a relationship? An empirical analysis using National Survey of the Work and Health of Nurses.

PubMed

Rajbhandary, Sameer; Basu, Kisalaya

2010-10-01

This paper investigates the relationship between the working conditions and illness- and injury-related absenteeism of full-time Registered Nurses (RNs) and Licensed Practical Nurses (LPNs). We used 2005 National Survey of the Work and Health of Nurses, which was designed to be representative of nurses employed in nursing in Canada in the fall of 2005. We estimated Negative Binomial regression models separately for RNs and LPNs with health related absenteeism as the dependent variable. The regressors include working conditions, work settings, and shift type/length along with socio-demographic variables. Depression is a significant determinant of absenteeism for both RNs and LPNs. However, workload and lack of respect are significant determinant of absenteeism for LPNs but not for RNs. Both RNs and LPNs working in other setting (physician offices, private nursing educations, educational institutions, governments and associations) will have less absenteeism than those working in hospitals. For LPNs, those working in long-term facility will also have less absenteeism than those working in hospitals. The length and type of shift also has significant effect on absenteeism. Improving working conditions with a resulting reduction in absenteeism might be an economic way to increase the labour supply of nurses without increasing new admissions or new recruits. Crown Copyright (c) 2010. Published by Elsevier Ireland Ltd. All rights reserved.

Evaluation of Two New Electronic Apex-Locator-Controlled Handpieces Using a NiTi Rotary File: An In Vitro Study.

PubMed

Nazarimoghadam, Kiumarz; Labaf, Hossein

2013-11-01

The aim of this in-vitro study was to compare the accuracy of two new electronic apex-locator controlled handpieces (EALHs) using the first rotary Mtwo file while rotating in the canal. A total of 36 extracted mandibular molar teeth were selected. The lengths of the mesio-buccal canals to the major foramina were measured directly using a size 10 K-file introduced in the canal until the tip was visible under a loupe and then 0.5 mm was subtracted from the recorded lengths as the actual working lengths (AWLs). Subsequently, the teeth were randomly assigned to two groups and embedded in an alginate model. Auto-stop function of the EALHs was preset at "0.5" mark and then electrical working lengths (EWLs) in groups 1 and 2 were recorded by VDW GOLD and Dentaport ZX, respectively. Analysis of variance (ANOVA, 1-way) and Tukey pairwise multiple comparison intervals (0.05) were used to compare the accuracy of the two electronic devices. For VDW GOLD, 61.1% of the measurements were within ±0.5 mm and 88.9% were within ±1 mm of the AWL. For Dentaport ZX, 88.9% of the measurements were within ±0.5 mm and 94.4% were within ±1mm of the AWL. There was no significant difference between AWLs and EWLs (p=0.466 for Dentaport ZX and p=0.283 for VDW Gold) and between the accuracy of the two devices in determining the EWL (p=0.8). Both Dentaport ZX and VDW Gold were suitable for determining working length using a rotary file. To avoid over instrumenting the canal, we recommend setting the devices to automatically stop or reverse the rotary file at 1 mm level.

Comparison of the EndoVac system to needle irrigation of root canals.

PubMed

Nielsen, Benjamin A; Craig Baumgartner, J

2007-05-01

Past studies have shown that current irrigation methods are effective at cleaning root canals coronally but less effective apically. To be effective, endodontic irrigants should ideally be delivered near working length. The purpose of this study was to compare the efficacy of the EndoVac irrigation system and needle irrigation to debride root canals at 1 and 3 mm from working length. One tooth of each matched pair was instrumented and irrigated by using the EndoVac, which uses negative pressure to deliver irrigating solutions to working length. The other tooth of the matched pair was instrumented and irrigated with a 30-gauge ProRinse irrigating needle. All teeth were irrigated with sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) for a predetermined amount of time, and total volume of irrigant used was recorded. After instrumentation and irrigation, the teeth were fixed, decalcified, and sectioned at 1 mm and 3 mm from working length. Serial sections were made and digitally photographed. The amount of remaining debris was determined as a percentage of the area of the canal lumen. Remaining debris and total irrigant were analyzed by using the Wilcoxon signed rank test at the 5% confidence level. At the 1-mm level, significantly less debris was found in the EndoVac group (p=0.0347). At the 3-mm level, there was no significant difference between groups. Significantly more irrigant was delivered with the EndoVac (p<0001). This study showed significantly better debridement at 1 mm from working length by using the EndoVac compared with needle irrigation.

A Formulation of the Earnings Function using the Concept of Occupational Investment.

ERIC Educational Resources Information Center

Shaw, Kathryn L.

1984-01-01

In this study, occupational investment--the accumulation of skills acquired to work within an occupation--is demonstrated to be a more significant determinant of earnings growth than length of experience. (SK)

Predictive minimum description length principle approach to inferring gene regulatory networks.

PubMed

Chaitankar, Vijender; Zhang, Chaoyang; Ghosh, Preetam; Gong, Ping; Perkins, Edward J; Deng, Youping

2011-01-01

Reverse engineering of gene regulatory networks using information theory models has received much attention due to its simplicity, low computational cost, and capability of inferring large networks. One of the major problems with information theory models is to determine the threshold that defines the regulatory relationships between genes. The minimum description length (MDL) principle has been implemented to overcome this problem. The description length of the MDL principle is the sum of model length and data encoding length. A user-specified fine tuning parameter is used as control mechanism between model and data encoding, but it is difficult to find the optimal parameter. In this work, we propose a new inference algorithm that incorporates mutual information (MI), conditional mutual information (CMI), and predictive minimum description length (PMDL) principle to infer gene regulatory networks from DNA microarray data. In this algorithm, the information theoretic quantities MI and CMI determine the regulatory relationships between genes and the PMDL principle method attempts to determine the best MI threshold without the need of a user-specified fine tuning parameter. The performance of the proposed algorithm is evaluated using both synthetic time series data sets and a biological time series data set (Saccharomyces cerevisiae). The results show that the proposed algorithm produced fewer false edges and significantly improved the precision when compared to existing MDL algorithm.

Comparison of the efficiency of rat papillary muscles during afterloaded isotonic contractions and contractions with sinusoidal length changes.

PubMed

Mellors, L J; Gibbs, C L; Barclay, C J

2001-05-01

The results of previous studies suggest that the maximum mechanical efficiency of rat papillary muscles is lower during a contraction protocol involving sinusoidal length changes than during one involving afterloaded isotonic contractions. The aim of this study was to compare directly the efficiency of isolated rat papillary muscle preparations in isotonic and sinusoidal contraction protocols. Experiments were performed in vitro (27 degrees C) using left ventricular papillary muscles from adult rats. Each preparation performed three contraction protocols: (i) low-frequency afterloaded isotonic contractions (10 twitches at 0.2 Hz), (ii) sinusoidal length change contractions with phasic stimulation (40 twitches at 2 Hz) and (iii) high-frequency afterloaded isotonic contractions (40 twitches at 2 Hz). The first two protocols resembled those used in previous studies and the third combined the characteristics of the first two. The parameters for each protocol were adjusted to those that gave maximum efficiency. For the afterloaded isotonic protocols, the afterload was set to 0.3 of the maximum developed force. The sinusoidal length change protocol incorporated a cycle amplitude of +/-5% resting length and a stimulus phase of -10 degrees. Measurements of force output, muscle length change and muscle temperature change were used to calculate the work and heat produced during and after each protocol. Net mechanical efficiency was defined as the proportion of the energy (enthalpy) liberated by the muscle that appeared as work. The efficiency in the low-frequency, isotonic contraction protocol was 21.1+/-1.4% (mean +/- s.e.m., N=6) and that in the sinusoidal protocol was 13.2+/-0.7%, consistent with previous results. This difference was not due to the higher frequency or greater number of twitches because efficiency in the high-frequency, isotonic protocol was 21.5+/-1.0%. Although these results apparently confirm that efficiency is protocol-dependent, additional experiments designed to measure work output unambiguously indicated that the method used to calculate work output in isotonic contractions overestimated actual work output. When net work output, which excludes work done by parallel elastic elements, rather than total work output was used to determine efficiency in afterloaded isotonic contractions, efficiency was similar to that for sinusoidal contractions. The maximum net mechanical efficiency of rat papillary muscles performing afterloaded isotonic or sinusoidal length change contractions was between 10 and 15%.

Suspension Bridges: A Merger of Physics, Engineering, and Art

ERIC Educational Resources Information Center

Greenslade, Thomas B., Jr.

1974-01-01

Discusses the physical principles underlying the design of a small scale suspension bridge, including its types and strength calculations. Included are the working equation and two formulas for determining the load per unit length. (CC)

Simulation, fabrication, and characterization of a tunable electrowetting-based lens with a wedge-shaped PDMS dielectric layer.

PubMed

Moghaddam, Mohammadreza Salehi; Latifi, H; Shahraki, Hamidreza; Cheri, Mohammad Sadegh

2015-04-01

Microlenses with tunable focal length have wide applications in optofluidic devices. This work presents a numerical and experimental investigation on a tunable electrowetting-based concave lens. Optical properties such as focal length of the lens and visibility of images were investigated numerically and experimentally. A finite element analysis and a ZEMAX simulation were used for determination of surface profile and focal length of the lens. The results show that the theoretical surface profile and focal length of the lens are in good agreement with the experimental ones. The lens has a wide tuning focal length equal to 6.5 (cm). Because the polydimethylsiloxane (PDMS) layer is wedge shaped (as both the dielectric and hydrophobic layers), lower applied voltage is needed. A commercial program was used to find the focal length of the lens from maximum visibility value by tuning the applied voltage.

Evaluation of 4 Commercial Viewing Devices for Radiographic Perceptibility and Working Length Determination.

PubMed

Lally, Trent; Geist, James R; Yu, Qingzhao; Himel, Van T; Sabey, Kent

2015-07-01

This study compared images displayed on 1 desktop monitor, 1 laptop monitor, and 2 tablets for the detection of contrast and working length interpretation, with a null hypothesis of no differences between the devices. Three aluminum blocks, with milled circles of varying depth, were radiographed at various exposure levels to create 45 images of varying radiographic density. Six observers viewed the images on 4 devices: Lenovo M92z desktop (Lenovo, Beijing, China), Lenovo Z580 laptop (Lenovo), iPad 3 (Apple, Cupertino, CA), and iPad mini (Apple). Observers recorded the number of circles detected for each image, and a perceptibility curve was used to compare the devices. Additionally, 42 extracted teeth were imaged with working length files affixed at various levels (short, flush, and long) relative to the anatomic apex. Observers measured the distance from file tip to tooth apex on each device. The absolute mean measurement error was calculated for each image. Analysis of variance tests compared the devices. Observers repeated their sessions 1 month later to evaluate intraobserver reliability as measured with weighted kappa tests. Interclass correlation coefficients compared interobserver reliability. There was no significant difference in perceptibility detection between the Lenovo M92z desktop, iPad 3, and iPad mini. However, on average, all 3 were significantly better than the Lenovo Z580 laptop (P values ≤.015). No significant difference in the mean absolute error was noted for working length measurements among the 4 viewing devices (P = .3509). Although all 4 viewing devices seemed comparable with regard to working length evaluation, the laptop computer screen had lower overall ability to perceive contrast differences. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Working length changes in curved canals after coronal flaring by using rotary files and hand file: An in vitro study.

PubMed

Kumar, Rahul; Khambete, Neha; Patil, Suvarna; Hoshing, Upendra; Medha, Ashish; Shetty, Roshan

2013-09-01

This in vitro investigation examined the effect of early coronal flaring (CF) and late CF on the working length (WL) in curved root canals. The objective of this study was to determine if canal length is altered as a result of CF in curved canals of molar roots. The conditions compared were combinations of (a) stainless steel hand files using Gates Glidden (G. G.) drills (SS) versus nickel-titanium rotary files (Ni-Ti); and (b) early CF (flaring completed before WL determination) versus late CF (flaring completed after WL determination). Selected were 90 canals of extracted maxillary or mandibular first molars (mesial root of mandibular molars and the mesiobuccal root of the maxillary molars) from three groups. CF was accomplished for the SS group using G. G. drills and for the Ni-Ti group using rotary ProTaper and Hero Shaper files. WL was determined by a digital vernier caliper before CF, immediately after CF, and again after canal preparation. A repeated measures analysis of variance (ANOVA) test and a Tukey's multiple prosthoc test were used for this study. Results indicated that WL decreased for all canals as a result of canal preparation. The mean decrease in WL was significantly greater for the SS group (-0.77 ± 0.42 mm) than for the Ni-Ti groups (-0.33 mm ± 0.44). Less change in WL occurred in all groups when initial WL was determined after CF. WL in curved canals consistently decreases during the course of instrumentation. Clinician should keep this in mind for better treatment outcome.

Rayleigh instability at small length scales.

PubMed

Gopan, Nandu; Sathian, Sarith P

2014-09-01

The Rayleigh instability (also called the Plateau-Rayleigh instability) of a nanosized liquid propane thread is investigated using molecular dynamics (MD). The validity of classical predictions at small length scales is verified by comparing the temporal evolution of liquid thread simulated by MD against classical predictions. Previous works have shown that thermal fluctuations become dominant at small length scales. The role and influence of the stochastic nature of thermal fluctuations in determining the instability at small length scale is also investigated. Thermal fluctuations are seen to dominate and accelerate the breakup process only during the last stages of breakup. The simulations also reveal that the breakup profile of nanoscale threads undergo modification due to reorganization of molecules by the evaporation-condensation process.

Analysis and selection of magnitude relations for the Working Group on Utah Earthquake Probabilities

USGS Publications Warehouse

Duross, Christopher; Olig, Susan; Schwartz, David

2015-01-01

Prior to calculating time-independent and -dependent earthquake probabilities for faults in the Wasatch Front region, the Working Group on Utah Earthquake Probabilities (WGUEP) updated a seismic-source model for the region (Wong and others, 2014) and evaluated 19 historical regressions on earthquake magnitude (M). These regressions relate M to fault parameters for historical surface-faulting earthquakes, including linear fault length (e.g., surface-rupture length [SRL] or segment length), average displacement, maximum displacement, rupture area, seismic moment (Mo ), and slip rate. These regressions show that significant epistemic uncertainties complicate the determination of characteristic magnitude for fault sources in the Basin and Range Province (BRP). For example, we found that M estimates (as a function of SRL) span about 0.3–0.4 units (figure 1) owing to differences in the fault parameter used; age, quality, and size of historical earthquake databases; and fault type and region considered.

Shaping abilities of two different engine-driven rotary nickel titanium systems or stainless steel balanced-force technique in mandibular molars.

PubMed

Matwychuk, Michael J; Bowles, Walter R; McClanahan, Scott B; Hodges, Jim S; Pesun, Igor J

2007-07-01

The purpose of this study was to compare apical transportation, working-length changes, and instrumentation time by using nickel-titanium (Ni-Ti) rotary file systems (crown-down method) or stainless steel hand files (balanced-force technique) in mesiobuccal canals of extracted mandibular molars. The curvature of each canal was determined and teeth placed into three equivalent groups. Group 1 was instrumented with Sequence (Brasseler USA, Savannah, GA) rotary files, group 2 with Liberator (Miltex Inc, York, PA) rotary files, and group 3 with Flex-R (Union Broach, New York, NY) files. Pre- and postoperative radiographs were superimposed to measure loss of working length and apical transportation as shown by changes in radius of curvature and the long-axis canal angle. Sequence rotary files, Liberator rotary files, and Flex-R hand files had similar effects on apical canal transportation and changes in working length, with no significant differences detected among the 3 groups. Hand instrumentation times were longer than with either Ni-Ti rotary group, whereas the rotary NiTi groups had a higher incidence of fracture.

Grizzly Staus Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spencer, Benjamin; Zhang, Yongfeng; Chakraborty, Pritam

2014-09-01

This report summarizes work during FY 2014 to develop capabilities to predict embrittlement of reactor pressure vessel steel, and to assess the response of embrittled reactor pressure vessels to postulated accident conditions. This work has been conducted a three length scales. At the engineering scale, 3D fracture mechanics capabilities have been developed to calculate stress intensities and fracture toughnesses, to perform a deterministic assessment of whether a crack would propagate at the location of an existing flaw. This capability has been demonstrated on several types of flaws in a generic reactor pressure vessel model. Models have been developed at themore » scale of fracture specimens to develop a capability to determine how irradiation affects the fracture toughness of material. Verification work has been performed on a previously-developed model to determine the sensitivity of the model to specimen geometry and size effects. The effects of irradiation on the parameters of this model has been investigated. At lower length scales, work has continued in an ongoing to understand how irradiation and thermal aging affect the microstructure and mechanical properties of reactor pressure vessel steel. Previously-developed atomistic kinetic monte carlo models have been further developed and benchmarked against experimental data. Initial work has been performed to develop models of nucleation in a phase field model. Additional modeling work has also been performed to improve the fundamental understanding of the formation mechanisms and stability of matrix defects caused.« less

Electronic measurement of variable torques in precision work technology

NASA Technical Reports Server (NTRS)

Maehr, M.

1978-01-01

Approaches for the determination of torques on the basis of length measurements are discussed. Attention is given to torque determinations in which the deformation of a shaft is measured, an electric measurement of the torsion angle, and an approach proposed by Buschmann (1970). Methods for a torque determination conducted with the aid of force measurements make use of piezoelectric approaches. The components used by these methods include a quartz crystal and a charge amplifier.

Development of Prototype HTS Components for Magnetic Suspension Applications

NASA Technical Reports Server (NTRS)

Haldar, P.; Hoehn, J., Jr.; Selvamanickam, V.; Farrell, R. A.; Balachandran, U.; Iyer, A. N.; Peterson, E.; Salazar, K.

1996-01-01

We have concentrated on developing prototype lengths of bismuth and thallium based silver sheathed superconductors by the powder-in-tube approach to fabricate high temperature superconducting (HTS) components for magnetic suspension applications. Long lengths of mono and multi filament tapes are presently being fabricated with critical current densities useful for maglev and many other applications. We have recently demonstrated the prototype manufacture of lengths exceeding 1 km of Bi-2223 multi filament conductor. Long lengths of thallium based multi-filament conductor have also been fabricated with practical levels of critical current density and improved field dependence behavior. Test coils and magnets have been built from these lengths and characterized over a range of temperatures and background fields to determine their performance. Work is in progress to develop, fabricate and test HTS windings that will be suitable for magnetic suspension, levitation and other electric power related applications.

Working length changes in curved canals after coronal flaring by using rotary files and hand file: An in vitro study

PubMed Central

Kumar, Rahul; Khambete, Neha; Patil, Suvarna; Hoshing, Upendra; Medha, Ashish; Shetty, Roshan

2013-01-01

Aim: This in vitro investigation examined the effect of early coronal flaring (CF) and late CF on the working length (WL) in curved root canals. Background: The objective of this study was to determine if canal length is altered as a result of CF in curved canals of molar roots. Study Design: The conditions compared were combinations of (a) stainless steel hand files using Gates Glidden (G. G.) drills (SS) versus nickel-titanium rotary files (Ni-Ti); and (b) early CF (flaring completed before WL determination) versus late CF (flaring completed after WL determination). Selected were 90 canals of extracted maxillary or mandibular first molars (mesial root of mandibular molars and the mesiobuccal root of the maxillary molars) from three groups. CF was accomplished for the SS group using G. G. drills and for the Ni-Ti group using rotary ProTaper and Hero Shaper files. WL was determined by a digital vernier caliper before CF, immediately after CF, and again after canal preparation. Statistical Analysis: A repeated measures analysis of variance (ANOVA) test and a Tukey's multiple prosthoc test were used for this study. Results: Results indicated that WL decreased for all canals as a result of canal preparation. The mean decrease in WL was significantly greater for the SS group (−0.77 ± 0.42 mm) than for the Ni-Ti groups (−0.33 mm ± 0.44). Less change in WL occurred in all groups when initial WL was determined after CF. Conclusion: WL in curved canals consistently decreases during the course of instrumentation. Clinician should keep this in mind for better treatment outcome. PMID:24082566

Ergonomic evaluation and comparison of wood harvesting systems in Northwest Russia.

PubMed

Gerasimov, Yuri; Sokolov, Anton

2014-03-01

A comparison of 14 currently applicable wood harvesting systems was assessed with respect to ergonomic point of view. For this purpose, the research method, based on the Hodges-Lehmann rule and the integrated work-severity rate of single machinery, was developed for ergonomic evaluation of cut-to-length, tree-length and full-tree harvesting systems. Altogether, about 130 different parameters of 36 units of equipment that impact on the ergonomics and work conditions were measured and estimated in interviews undertaken directly at forestry harvesting workplaces in 15 logging companies in the Republic of Karelia, Northwest Russia. Then the results were compared to the effective norms, and the degree of compliance with the stipulated values was determined. The estimates obtained for the degree of compliance were combined. This permits a direct comparison of the workload on forestry harvesting workers such as operators, lumberjacks and choker setters. In many respects, the current ergonomic standard is standard, except for the operators of cable skidders, chainsaws and choker settings. Visibility and work postures were considered to be the most critical features influencing the operator's performance. Problems still exist, despite the extensive development of cabs. The best working conditions in terms of harvesting systems were provided by "harvester + forwarder" in cut-to-length harvesting, and "feller-buncher + grapple skidder" in full-tree harvesting. The motor-manual tree-length harvesting performed with cable skidders showed the worst results in terms of ergonomics. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Louis Essen and the Velocity of Light: From Wartime Radar to Unit of Length

NASA Astrophysics Data System (ADS)

Essen, Ray

2010-03-01

Louis Essen (1908-1997), working at the National Physical Laboratory in Teddington, England, was the first scientist to realize that the value for the velocity of light used widely during World War II was incorrect. In 1947 he published his first determination of it, which was 16 kilometers per second higher than the accepted value, causing a great deal of controversy in the scientific community. His new value was not accepted for several years, until it was shown that it improved the precision of range-finding by radar. Essen’s result has remained as the internationally accepted value despite a number of attempts to improve on it. I discuss Essen’s work and also examine other optical and nonoptical determinations that were made in the United States, and their limits of accuracy. I also identify the reasons why it took so long for Essen’s new value to be accepted, and how it led to changes in the definition of the units of length and time.

Holocene Activity of the Quelccaya Ice Cap: A Working Model

NASA Astrophysics Data System (ADS)

Lowell, T. V.; Smith, C. A.; Kelly, M. A.; Stroup, J. S.

2012-12-01

The patterns and magnitudes of past climate change in the topics are still under discussion. We contribute here by reporting on patterns of glacier length changes of the largest glacier in the tropics, Quelccaya Ice Cap (~13.9°S, 70.9°W, summit at 5645 m). This ice cap has several local domes that may have different patterns of length changes because of differing elevations of the domes (high to the north, lower to the south). Prior work (Mark et al. 2003, Abbott et al., 2004; Thompson et al., 2005; Buffen, et al., 2009), new radiocarbon ages, and stratigraphic and geomorphic relationships are used to determine the general pattern of length changes for the outlets from this ice cap. We exploit geomorphic relationships and present new radiocarbon ages on interpreted stratigraphic sections to determine the pattern of length changes for this ice cap. Ice retreated during late glacial times (Rodbell and Seltzer, 2000; Kelly et al., in press). By 11,400 yr BP it had reached a position ~1.2 km beyond its present (2000 AD) extent. While length during the early Holocene is problematic, present evidence permits, but does not prove, extents of 0.5 to 1.0 km down-valley from the present margin. Between 6400 and 4400 yr BP the ice cap was smaller than present, but it advanced multiple times during the late Holocene. Lengths of up to 1 km beyond present were achieved at 3400 yr BP and ~500 yr BP. Additionally, the ice advanced to 0.8 km beyond its present margin at 1600 yr BP. Because these glaciers were temperate, we take these lengths to represent primarily changes in temperature. This may suggest that lowering insolation values in the northern hemisphere during the Holocene provide a first order control on tropical temperatures. Alternatively, it may be that major reorganization of the topical circulation belts about 5000 yr BP yields two configurations of the QIC and hence Holocene temperatures - one at the present ice margin and and the second about 1 km beyond the present ice margin. In either case, the pulsating glacier lengths indicate a dynamic Holocene climate.

Acoustic Emission and Echo Signal Compensation Techniques Applied to an Ultrasonic Logging-While-Drilling Caliper.

PubMed

Yao, Yongchao; Ju, Xiaodong; Lu, Junqiang; Men, Baiyong

2017-06-10

A logging-while-drilling (LWD) caliper is a tool used for the real-time measurement of a borehole diameter in oil drilling engineering. This study introduces the mechanical structure and working principle of a new LWD caliper based on ultrasonic distance measurement (UDM). The detection range is a major performance index of a UDM system. This index is determined by the blind zone length and remote reflecting interface detection capability of the system. To reduce the blind zone length and detect near the reflecting interface, a full bridge acoustic emission technique based on bootstrap gate driver (BGD) and metal-oxide-semiconductor field effect transistor (MOSFET) is designed by analyzing the working principle and impedance characteristics of a given piezoelectric transducer. To detect the remote reflecting interface and reduce the dynamic range of the received echo signals, the relationships between the echo amplitude and propagation distance of ultrasonic waves are determined. A signal compensation technique based on time-varying amplification theory, which can automatically change the gain according to the echo arrival time is designed. Lastly, the aforementioned techniques and corresponding circuits are experimentally verified. Results show that the blind zone length in the UDM system of the LWD caliper is significantly reduced and the capability to detect the remote reflecting interface is considerably improved.

Acoustic Emission and Echo Signal Compensation Techniques Applied to an Ultrasonic Logging-While-Drilling Caliper

PubMed Central

Yao, Yongchao; Ju, Xiaodong; Lu, Junqiang; Men, Baiyong

2017-01-01

A logging-while-drilling (LWD) caliper is a tool used for the real-time measurement of a borehole diameter in oil drilling engineering. This study introduces the mechanical structure and working principle of a new LWD caliper based on ultrasonic distance measurement (UDM). The detection range is a major performance index of a UDM system. This index is determined by the blind zone length and remote reflecting interface detection capability of the system. To reduce the blind zone length and detect near the reflecting interface, a full bridge acoustic emission technique based on bootstrap gate driver (BGD) and metal-oxide-semiconductor field effect transistor (MOSFET) is designed by analyzing the working principle and impedance characteristics of a given piezoelectric transducer. To detect the remote reflecting interface and reduce the dynamic range of the received echo signals, the relationships between the echo amplitude and propagation distance of ultrasonic waves are determined. A signal compensation technique based on time-varying amplification theory, which can automatically change the gain according to the echo arrival time is designed. Lastly, the aforementioned techniques and corresponding circuits are experimentally verified. Results show that the blind zone length in the UDM system of the LWD caliper is significantly reduced and the capability to detect the remote reflecting interface is considerably improved. PMID:28604603

Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children: A cross-sectional study.

PubMed

Martín Lorenzo, Teresa; Albi Rodríguez, Gustavo; Rocon, Eduardo; Martínez Caballero, Ignacio; Lerma Lara, Sergio

2017-07-01

Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles' force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop joint power and work. However, static fascicle length measurements may not be taking sarcomere length differences into account. Thus, we considered relative fascicle excursions through passive ankle dorsiflexion may better correlate with the capacity to generate joint power and work than fascicle length. Therefore, the aim of the present study was to determine if medial gastrocnemius relative fascicle excursions correlate with ankle joint power and work generation during gait in typically developing children. A sample of typically developing children (n = 10) were recruited for this study and data analysis was carried out on 20 legs. Medial gastrocnemius relative fascicle excursion from resting joint angle to maximum dorsiflexion was estimated from trigonometric relations of medial gastrocnemius pennation angle and thickness obtained from B-mode real-time ultrasonography. Furthermore, a three-dimensional motion capture system was used to obtain ankle joint work and power during the stance phase of gait. Significant correlations were found between relative fascicle excursion and peak power absorption (-) r(14) = -0.61, P = .012 accounting for 31% variability, positive work r(18) = 0.56, P = .021 accounting for 31% variability, and late stance positive work r(15) = 0.51, P = .037 accounting for 26% variability. The large unexplained variance may be attributed to mechanics of neighboring structures (e.g., soleus or Achilles tendon mechanics) and proximal joint kinetics which may also contribute to ankle joint power and work performance, and were not taken into account. Further studies are encouraged to provide greater insight on the relationship between relative fascicle excursions and joint function.

Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children

PubMed Central

Martín Lorenzo, Teresa; Albi Rodríguez, Gustavo; Rocon, Eduardo; Martínez Caballero, Ignacio; Lerma Lara, Sergio

2017-01-01

Abstract Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles’ force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop joint power and work. However, static fascicle length measurements may not be taking sarcomere length differences into account. Thus, we considered relative fascicle excursions through passive ankle dorsiflexion may better correlate with the capacity to generate joint power and work than fascicle length. Therefore, the aim of the present study was to determine if medial gastrocnemius relative fascicle excursions correlate with ankle joint power and work generation during gait in typically developing children. A sample of typically developing children (n = 10) were recruited for this study and data analysis was carried out on 20 legs. Medial gastrocnemius relative fascicle excursion from resting joint angle to maximum dorsiflexion was estimated from trigonometric relations of medial gastrocnemius pennation angle and thickness obtained from B-mode real-time ultrasonography. Furthermore, a three-dimensional motion capture system was used to obtain ankle joint work and power during the stance phase of gait. Significant correlations were found between relative fascicle excursion and peak power absorption (–) r(14) = −0.61, P = .012 accounting for 31% variability, positive work r(18) = 0.56, P = .021 accounting for 31% variability, and late stance positive work r(15) = 0.51, P = .037 accounting for 26% variability. The large unexplained variance may be attributed to mechanics of neighboring structures (e.g., soleus or Achilles tendon mechanics) and proximal joint kinetics which may also contribute to ankle joint power and work performance, and were not taken into account. Further studies are encouraged to provide greater insight on the relationship between relative fascicle excursions and joint function. PMID:28723790

The noise factor in railway locomotives.

PubMed

Rotter, T

1982-09-01

This article concerns the problem of acoustic work conditions on railway locomotives. The objective results of sonometric surveys in locomotive cabins are compared with subject data received from locomotive crews obtained by means of a specific questionnaire 'The Subjective Estimation of Noise'. The analysis touched 9 type of locomotives; steam, diesel and electric engines. We asked drivers of different age groups and with varying lengths of professional service for their opinions The aim of the investigation was to determine the following points: 1. to analyse the drivers' subjective estimation of the noise in the locomotive cabins; 2. to define length of time for which the driver remains under the influence of the noise after finishing work; 3. to investigate the question of perception and understanding of sounds and vocal signals used in the locomotive. These problems are a small part of the general plan to improve work conditions on the Polish National Railways.

18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Replacements

Code of Federal Regulations, 2011 CFR

2011-04-01

.... Typical work spaces are: Item Typical extra area (width/length) Two lane road (bored) 25-50 by 100 feet. Four lane road (bored) 50 by 100 feet. Major river (wet cut) 100 by 200 feet. Intermediate stream (wet...

Determination of Probe Volume Dimensions in Coherent Measurement Techniques

NASA Technical Reports Server (NTRS)

Tedder, Sarah A.; Weikl, Markus C.; Seeger, Thomas; Leipertz, Alfred

2008-01-01

When investigating combustion phenomena with pump-probe techniques, the spatial resolution is given by the overlapping region of the laser beams and thus defines the probe volume size. The size of this probe volume becomes important when the length scales of interest are on the same order or smaller. In this work, we present a new approach to measure the probe volume in three dimensions (3-D), which can be used to determine the probe volume length, diameter, and shape. The optical arrangement and data evaluation are demonstrated for a dual-pump dual-broadband coherent anti-Stokes Raman scattering (CARS) setup which is used for combustion diagnostics. This new approach offers a simple, quick alternative with more capabilities than formerly used probe volume measurement methods.

Verification of relationships between anthropometric variables among ureteral stents recipients and ureteric lengths: a challenge for Vitruvian-da Vinci theory.

PubMed

Acelam, Philip A

2015-01-01

To determine and verify how anthropometric variables correlate to ureteric lengths and how well statistical models approximate the actual ureteric lengths. In this work, 129 charts of endourological patients (71 females and 58 males) were studied retrospectively. Data were gathered from various research centers from North and South America. Continuous data were studied using descriptive statistics. Anthropometric variables (age, body surface area, body weight, obesity, and stature) were utilized as predictors of ureteric lengths. Linear regressions and correlations were used for studying relationships between the predictors and the outcome variables (ureteric lengths); P-value was set at 0.05. To assess how well statistical models were capable of predicting the actual ureteric lengths, percentages (or ratios of matched to mismatched results) were employed. The results of the study show that anthropometric variables do not correlate well to ureteric lengths. Statistical models can partially estimate ureteric lengths. Out of the five anthropometric variables studied, three of them: body frame, stature, and weight, each with a P<0.0001, were significant. Two of the variables: age (R (2)=0.01; P=0.20) and obesity (R (2)=0.03; P=0.06), were found to be poor estimators of ureteric lengths. None of the predictors reached the expected (match:above:below) ratio of 1:0:0 to qualify as reliable predictors of ureteric lengths. There is not sufficient evidence to conclude that anthropometric variables can reliably predict ureteric lengths. These variables appear to lack adequate specificity as they failed to reach the expected (match:above:below) ratio of 1:0:0. Consequently, selections of ureteral stents continue to remain a challenge. However, height (R (2)=0.68) with the (match:above:below) ratio of 3:3:4 appears suited for use as estimator, but on the basis of decision rule. Additional research is recommended for stent improvements and ureteric length determinations.

Verification of relationships between anthropometric variables among ureteral stents recipients and ureteric lengths: a challenge for Vitruvian-da Vinci theory

PubMed Central

Acelam, Philip A

2015-01-01

Objective To determine and verify how anthropometric variables correlate to ureteric lengths and how well statistical models approximate the actual ureteric lengths. Materials and methods In this work, 129 charts of endourological patients (71 females and 58 males) were studied retrospectively. Data were gathered from various research centers from North and South America. Continuous data were studied using descriptive statistics. Anthropometric variables (age, body surface area, body weight, obesity, and stature) were utilized as predictors of ureteric lengths. Linear regressions and correlations were used for studying relationships between the predictors and the outcome variables (ureteric lengths); P-value was set at 0.05. To assess how well statistical models were capable of predicting the actual ureteric lengths, percentages (or ratios of matched to mismatched results) were employed. Results The results of the study show that anthropometric variables do not correlate well to ureteric lengths. Statistical models can partially estimate ureteric lengths. Out of the five anthropometric variables studied, three of them: body frame, stature, and weight, each with a P<0.0001, were significant. Two of the variables: age (R2=0.01; P=0.20) and obesity (R2=0.03; P=0.06), were found to be poor estimators of ureteric lengths. None of the predictors reached the expected (match:above:below) ratio of 1:0:0 to qualify as reliable predictors of ureteric lengths. Conclusion There is not sufficient evidence to conclude that anthropometric variables can reliably predict ureteric lengths. These variables appear to lack adequate specificity as they failed to reach the expected (match:above:below) ratio of 1:0:0. Consequently, selections of ureteral stents continue to remain a challenge. However, height (R2=0.68) with the (match:above:below) ratio of 3:3:4 appears suited for use as estimator, but on the basis of decision rule. Additional research is recommended for stent improvements and ureteric length determinations. PMID:26317082

A New Look: Basals of the Nineties.

ERIC Educational Resources Information Center

Gieniec, Colleen; Westerholt, Sheri

A study determined whether basal series published in 1993 are consistent with research on literacy development which indicates that children need authentic text that is full-length, unedited and connects content to the reading experience. Pupil editions, teacher's manuals, lesson structure, skills taught, the amount of skill work compared to…

Evaluation of performance and maximum length of continuous decks in bridges : part 1.

DOT National Transportation Integrated Search

2011-06-01

The purpose of this research was to evaluate the performance history of continuous bridge decks in the State of Georgia, to determine why the current design detail works, to recommend a new design detail, and to recommend the maximum and/or optimum l...

Time-to-Degree and the Business Cycle

ERIC Educational Resources Information Center

Messer, Dolores; Wolter, Stefan C.

2010-01-01

This paper presents the results of an empirical investigation trying to explain individual time-to-degree variances with business cycle fluctuations. Assuming that students determine the optimum study length at university weighing up the cost of an additional semester against the consumption benefit of studying and not yet working, the general…

Evaluation of ultra-low expansion spacer in the Fabry-Perot cavity with optical frequency comb

NASA Astrophysics Data System (ADS)

Šmíd, Radek; Čížek, Martin; Buchta, Zdeněk.; Lazar, Josef; Číp, Ondřej

2012-01-01

The work presents measurements of the length stability of Zerodur glass ceramic with temperature change. Measurement of this thermal characteristic is necessary for determination of the optimal temperature at which the Zerodur glass ceramic has a coefficient of thermal expansion close to zero. The principle of the measurement is to monitor the length changes using an optical resonator with a cavity mirror spacer made from the Zerodur material to be studied. The resonator is placed inside a vacuum chamber with a temperature control. A tunable laser diode is locked to a certain optical mode of the resonator to monitor the optical frequency of this mode. A beat-note signal from optical mixing between the laser and a stabilized femtosecond frequency comb is detected and processed. The temperature dependence of the glass ceramics was determined and analyzed. The resolution of the length measurement of the experimental set-up is on the order of 0.1 nm.

Study of the thermal stability of Zerodur glass ceramics suitable for a scanning probe microscope frame

NASA Astrophysics Data System (ADS)

Číp, Ondřej; Šmíd, Radek; Čížek, Martin; Buchta, Zdeněk; Lazar, Josef

2012-04-01

The work presents measurements of the length stability of Zerodur glass ceramic with temperature change. Measurement of this thermal characteristic is necessary for determination of the optimal temperature at which the Zerodur glass ceramic has a coefficient of thermal expansion close to zero. The principle of the measurement is to monitor the length changes using an optical resonator with a cavity mirror spacer made from the Zerodur material to be studied. The resonator is placed inside a vacuum chamber with a temperature control. A tunable laser diode is locked to a certain optical mode of the resonator to monitor the optical frequency of this mode. A beat-note signal from optical mixing between the laser and a stabilized femtosecond frequency comb is detected and processed. The temperature dependence of the glass ceramics was determined and analyzed. The resolution of the length measurement of the experimental set-up is on the order of 0.1 nm.

Evaluation of Crack Arrest Toughness ( K IA) of P91 Steel in Various Cold Worked and Thermally Aged Conditions

NASA Astrophysics Data System (ADS)

Sathyanarayanan, S.; Moitra, A.; Sasikala, G.; Bhaduri, A. K.

2015-02-01

K IA is increasingly being regarded as a characteristic fracture toughness below which cleavage fracture does not occur. Its evaluation from small-sized Charpy specimens would be advantageous for applications in power plant industries. In this study, K IA has been evaluated for P91 steel in various cold worked and thermally aged conditions. Evaluation of K IA requires determination of crack arrest load( P arrest) and crack arrest length( a arrest). The main challenge is in the determination of a arrest due to the non-availability of standard methodologies and the absence of unequivocal microstructural signatures on the fracture surface in this steel to identify crack arrest. a arrest has been determined using the analytical Key- Curve methodology which has proven successful for this steel in unaged condition. The applicability of the Key- Curve method is validated by the good agreement of the determined final crack length with that measured optically on unbroken specimens of N&T and subsequently 15% cold-worked P91 steel which had been previously aged at 650 °C for 5000 h. Mean K IA varies from 47.46 MPa√m (NT steel aged at 600 °C for 5000 h) to 69.85 MPa√m(NT + 15% cw steel aged at 650 °C for 10000 h) for the various cold worked and aged datasets. K IA is found to be an average property unlike initiation toughness ( K Jd) which shows statistical scatter. Mean K IA is found to be in reasonable agreement with the lower bound values of cleavage initiation toughness ( K Jd) for the datasets in this study.

Brillouin Scattering of Picosecond Laser Pulses in Preformed, Short-Scale-Length Plasmas

NASA Astrophysics Data System (ADS)

Gaeris, A. C.; Fisher, Y.; Delettrez, J. A.; Meyerhofer, D. D.

1996-11-01

Brillouin scattering (BS) has been studied in short-scale-length, preformed plasmas. The backscattered and specularly reflected light resulting from the interaction of high-power picosecond pulses with preformed silicon plasmas has been measured. A first laser pulse forms a short-scale-length plasma -- without significant BS -- while a second delayed pulse interacts with an expanded, drifting underdense region of the plasma with density scale length (0 <= Ln <= 600 λ _L). The pulses are generated at λ L = 1054 nm, with intensities up to 10^16 W/cm^2. The backscattered light spectra, threshold intensities, and enhanced reflectivities have been determined for different plasma-density scale lengths and are compared to Liu, Rosenbluth, and White's(C. S. Liu, M. N. Rosenbluth, and R. B. White, Phys. Fluids 17, 1211 (1974).) WKB treatment of stimulated Brillouin scattering in inhomogeneous drifting plasmas. This work was supported by the U.S. Department of Energy Office of Inertial Confinement Fusion under Cooperative Agreement No. DE-FC03-92SF19460.

Clinical efficacy of electronic apex locators: systematic review.

PubMed

Martins, Jorge N R; Marques, Duarte; Mata, António; Caramês, João

2014-06-01

Apical constriction has been proposed as the most appropriate apical limit for the endodontic working length. Despite being the most used, some limitations are attributed to the radiographic method of working length determination. It lacks precision because it is based on the average position of the apical constriction. The electronic apex locators have been presented as an alternative to the odontometry performed by radiography. These devices detect the transition of the pulp to the periodontal tissue, which is anatomically very close to the apical constriction and may perform with improved accuracy. A systematic review was performed to compare the radiographic and electronic methods. Clinical studies that compared both methods were searched for on 7 electronic databases, a manual search was performed on the bibliography of articles collected on the electronic databases, and the authors were contacted to ask for references of more research not detected on the electronic and manual search. Twenty-one articles were selected. The majority were comparative or evaluation studies, and very few clinical studies comparing both methods are available. Several methodological limitations are present on the collected articles and debated in this review. Although the available scientific evidence base is short and at considerable risk of bias, it is still possible to conclude that the apical locator reduces the patient radiation exposure and also that the electronic method may perform better on the working length determination. At least one radiographic control should be performed to detect possible errors of the electronic devices. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

[Root canal treatment of mandibular second premolar tooth with taurodontism].

PubMed

Vujasković, Mirjana; Karadzić, Branislav; Miletić, Vesna

2008-01-01

Taurodontism is a morphoanatomical change in the shape of a tooth. An enlarged body of a tooth with smaller than usual roots is a characteristic feature. Internal tooth anatomy correlates with this appearance, which means that a taurodontal tooth has a large pulp chamber and apically positioned furcations. This dental anomaly may be associated with different syndromes and congenital discoders. The case report presents the patient of a rare case of taurodontism in the mandibular second premolar with chronic periodontitis. Endodontic treatment was performed after dental history and clinical examination. Special care is required in all segments of endodontic treatment of a taurodontal tooth from the identification orifice, canal exploration, determining working length, cleaning and shaping and obturation of the root canal. Precurved K-file was used for canal exploration and location of the furcation. One mesial and one distal canal with the buccal position were identified in the apical third of the root canal. The working lengths of two canals were determined by radiographic interpretation with two K-files in each canal and verified with the apex locator. During canal instrumentation, the third canal was located in the disto-lingual position. The working length of the third canal was established using the apex locator. Thorough knowledge of tooth anatomy and its variations can lead to lower percentage of endodontic failure. Each clinical case involving these teeth should be investigated carefully, clinically and radiographically to detect additional root canals. High quality radiographs from different angles and proper instrumentarium improve the quality of endodontic procedure.

Conformation and stretching of end-tethered polymers in pressure-driven flow under confinement

NASA Astrophysics Data System (ADS)

Roy, Tamal; Hardt, Steffen; InstituteNano-; Microfludics, Technische Universität Darmstadt Team

2016-11-01

Understanding of the conformation and dynamics of polymers under confinement is important for both fundamental studies and applications. We experimentally study the conformation and stretching of surface-tethered polymer chains confined between parallel surfaces and exposed to a pressure-driven flow. λ-DNA molecules are tethered to the wall of a microchannel of height smaller than the contour lengths of the molecules. The DNA molecules, stained with a fluorescent dye, are visualized by epifluorescence and laser-scanning confocal microscopy (LSCM). The effects of the channel height, flow rate and contour length on the extension of the molecules are determined from epifluorescence images. From LSCM images the complete conformation and orientation of the DNA molecules is inferred. We find that the fractional extension of the molecules is uniquely determined by the fluid shear stress at the tethering surface and the chain contour length. There is no explicit influence of the channel height in the range of contour lengths we consider. We also derive analytical scaling relationships (in the weak and strong extension limits) that explain the experimentally observed stretching characteristics. This work is supported by Deutsche Forschungsgemeinschaft (Grant No. HA 2696/33-1).

Generation of a reliable full-length cDNA of infectiousTembusu virus using a PCR-based protocol.

PubMed

Liang, Te; Liu, Xiaoxiao; Cui, Shulin; Qu, Shenghua; Wang, Dan; Liu, Ning; Wang, Fumin; Ning, Kang; Zhang, Bing; Zhang, Dabing

2016-02-02

Full-length cDNA of Tembusu virus (TMUV) cloned in a plasmid has been found instable in bacterial hosts. Using a PCR-based protocol, we generated a stable full-length cDNA of TMUV. Different cDNA fragments of TMUV were amplified by reverse transcription (RT)-PCR, and cloned into plasmids. Fragmented cDNAs were amplified and assembled by fusion PCR to produce a full-length cDNA using the recombinant plasmids as templates. Subsequently, a full-length RNA was transcribed from the full-length cDNA in vitro and transfected into BHK-21 cells; infectious viral particles were rescued successfully. Following several passages in BKH-21 cells, the rescued virus was compared with the parental virus by genetic marker checks, growth curve determinations and animal experiments. These assays clearly demonstrated the genetic and biological stabilities of the rescued virus. The present work will be useful for future investigations on the molecular mechanisms involved in replication and pathogenesis of TMUV. Copyright © 2015 Elsevier B.V. All rights reserved.

Comparison of two methods of digital imaging technology for small diameter K-file length determination.

PubMed

Maryam, Ehsani; Farida, Abesi; Farhad, Akbarzade; Soraya, Khafri

2013-11-01

Obtaining the proper working length in endodontic treatment is essential. The aim of this study was to compare the working length (WL) assessment of small diameter K-files using the two different digital imaging methods. The samples for this in-vitro experimental study consisted of 40 extracted single-rooted premolars. After access cavity preparation, the ISO files no. 6, 8, and 10 stainless steel K-files were inserted in the canals in the three different lengths to evaluate the results in a blinded manner: At the level of apical foramen(actual)1 mm short of apical foramen2 mm short of apical foramen A digital caliper was used to measure the length of the files which was considered as the Gold Standard. Five observers (two oral and maxillofacial radiologists and three endodontists) observed the digital radiographs which were obtained using PSP and CCD digital imaging sensors. The collected data were analyzed by SPSS 17 and Repeated Measures Paired T-test. In WL assessment of small diameter K-files, a significant statistical relationship was seen among the observers of two digital imaging techniques (P<0.001). However, no significant difference was observed between the two digital techniques in WL assessment of small diameter K-files (P<0.05). PSP and CCD digital imaging techniques were similar in WL assessment of canals using no. 6, 8, and 10 K-files.

Contraction dynamics and function of the muscle-tendon complex depend on the muscle fibre-tendon length ratio: a simulation study.

PubMed

Mörl, Falk; Siebert, Tobias; Häufle, Daniel

2016-02-01

Experimental studies show different muscle-tendon complex (MTC) functions (e.g. motor or spring) depending on the muscle fibre-tendon length ratio. Comparing different MTC of different animals examined experimentally, the extracted MTC functions are biased by, for example, MTC-specific pennation angle and fibre-type distribution or divergent experimental protocols (e.g. influence of temperature or stimulation on MTC force). Thus, a thorough understanding of variation of these inner muscle fibre-tendon length ratios on MTC function is difficult. In this study, we used a hill-type muscle model to simulate MTC. The model consists of a contractile element (CE) simulating muscle fibres, a serial element (SE) as a model for tendon, and a parallel elastic element (PEE) modelling tissue in parallel to the muscle fibres. The simulation examines the impact of length variations of these components on contraction dynamics and MTC function. Ensuring a constant overall length of the MTC by L(MTC) = L(SE) + L(CE), the SE rest length was varied over a broad physiological range from 0.1 to 0.9 MTC length. Five different MTC functions were investigated by simulating typical physiological experiments: the stabilising function with isometric contractions, the motor function with contractions against a weight, the capability of acceleration with contractions against a small inertial mass, the braking function by decelerating a mass, and the spring function with stretch-shortening cycles. The ratio of SE and CE mainly determines the MTC function. MTC with comparably short tendon generates high force and maximal shortening velocity and is able to produce maximal work and power. MTC with long tendon is suitable to store and release a maximum amount of energy. Variation of muscle fibre-tendon ratio yielded two peaks for MTC's force response for short and long SE lengths. Further, maximum work storage capacity of the SE is at long relL(SE,0). Impact of fibre-tendon length ratio on MTC functions will be discussed. Considering a constant set of MTC parameters, quantitative changes in MTC performance (work, stiffness, force, energy storage, dissipation) depending on varying muscle fibre-tendon length ratio were provided, which enables classification and grading of different MTC designs.

Optimal Levels of Emotional Arousal in Experiential Therapy of Depression

ERIC Educational Resources Information Center

Carryer, Jonathan R.; Greenberg, Leslie S.

2010-01-01

Objective: To determine the relationship between length of time spent expressing highly aroused emotion and therapeutic outcome. Method: Thirty-eight clients (14 male, 24 female) between the ages of 22 and 60 years (M = 39.5, SD = 9.71), treated for depression with experiential therapy, were rated on working alliance and expressed emotional…

Hanbury-Brown and Twiss correlations between pion pairs from gold + gold collisions at 6, 8, and 10.8 GeV/u

NASA Astrophysics Data System (ADS)

Holzman, Burt

The E917 experiment studied Au+Au collisions at beam energies of 6, 8, and 10.8 GeV per nucleon at the Alternating Gradient Synchrotron at Brookhaven National Laboratory in New York. Hanbury-Brown and Twiss correlations between pion pairs were investigated in order to determine the spatiotemporal structure of the collision region which serves as the source for these produced particles. Three separate correlation analyses were carried out in this work. One-dimensional correlation radii and their dependence on beam energy are measured. No systematic trends with energy are observed, and the overall radius roughly corresponds to the geometric size of the collision zone. In a simple model, three-dimensional correlation radii which assume an azimuthally asymmetric source are determined at the full beam energy of 10.8 GeV/u. The radius transverse to the beam direction along the reaction plane is compared to the transverse radius orthogonal to the reaction plane. A small difference is observed between the two radii. In a state-of-the-art model, it is possible to determine the ``lengths of homogeneity'' of the collision zone without invoking the assumptions inherent in the simple model, six-dimensional correlation radii are determined at the full beam energy of 10.8 GeV/u, and consequently the in-plane length of homogeneity, out-of- plane length, longitudinal length, and emission duration of the source are determined. Additionally, the magnitude of the tilt of the collision region in the reaction plane is measured and found to be -31° +/- 32°. The measurement of the in-plane and out-of-plane homogeneity lengths is not sensitive enough to distinguish between an oblate or prolate source, but provides a blueprint for future statistics-rich analyses to follow.

Experimental verification of the capillary plasma triggered long spark gap under the extremely low working coefficient in air

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, D.; Yang, L. J., E-mail: yanglj@mail.xjtu.edu.cn; Ma, J. B.

The paper has proposed a new triggering method for long spark gap based on capillary plasma ejection and conducted the experimental verification under the extremely low working coefficient, which represents that the ratio of the spark gap charging voltage to the breakdown voltage is particularly low. The quasi-neutral plasma is ejected from the capillary and develops through the axial direction of the spark gap. The electric field in the spark gap is thus changed and its breakdown is incurred. It is proved by the experiments that the capillary plasma ejection is effective in triggering the long spark gap under themore » extremely low working coefficient in air. The study also indicates that the breakdown probabilities, the breakdown delay, and the delay dispersion are all mainly determined by the characteristics of the ejected plasma, including the length of the plasma flow, the speed of the plasma ejection, and the ionization degree of the plasma. Moreover, the breakdown delay and the delay dispersion increase with the length of the long spark gap, and the polarity effect exists in the triggering process. Lastly, compared with the working patterns of the triggering device installed in the single electrode, the working pattern of the devices installed in both the two electrodes, though with the same breakdown process, achieves the ignition under longer gap distance. To be specific, at the gap length of 14 cm and the working coefficient of less than 2%, the spark gap is still ignited accurately.« less

Feasibility analysis of large length-scale thermocapillary flow experiment for the International Space Station

NASA Astrophysics Data System (ADS)

Alberts, Samantha J.

The investigation of microgravity fluid dynamics emerged out of necessity with the advent of space exploration. In particular, capillary research took a leap forward in the 1960s with regards to liquid settling and interfacial dynamics. Due to inherent temperature variations in large spacecraft liquid systems, such as fuel tanks, forces develop on gas-liquid interfaces which induce thermocapillary flows. To date, thermocapillary flows have been studied in small, idealized research geometries usually under terrestrial conditions. The 1 to 3m lengths in current and future large tanks and hardware are designed based on hardware rather than research, which leaves spaceflight systems designers without the technological tools to effectively create safe and efficient designs. This thesis focused on the design and feasibility of a large length-scale thermocapillary flow experiment, which utilizes temperature variations to drive a flow. The design of a helical channel geometry ranging from 1 to 2.5m in length permits a large length-scale thermocapillary flow experiment to fit in a seemingly small International Space Station (ISS) facility such as the Fluids Integrated Rack (FIR). An initial investigation determined the proposed experiment produced measurable data while adhering to the FIR facility limitations. The computational portion of this thesis focused on the investigation of functional geometries of fuel tanks and depots using Surface Evolver. This work outlines the design of a large length-scale thermocapillary flow experiment for the ISS FIR. The results from this work improve the understanding thermocapillary flows and thus improve technological tools for predicting heat and mass transfer in large length-scale thermocapillary flows. Without the tools to understand the thermocapillary flows in these systems, engineers are forced to design larger, heavier vehicles to assure safety and mission success.

[Correlation of mental fatigue due to work load and professional qualifications of physicians].

PubMed

Wichrowski, A; Dudek, B

1988-01-01

The results presented in the paper refer to the relationship between physicians' professional qualifications and mental fatigue. It was that professional qualifications determining man's capabilities affect the level and structure of mental fatigue caused by work. Furthermore, it was assumed that this workload is multidimensional, and so its following five dimensions were singled out: mental difficulties, monotony, risk and responsibility, moral conflicts and dilemmas. The level of qualifications was measured by the length of employment and specialization and scientific degrees. The studies involved 10% of randomly selected physicians from all over Poland. The obtained results indicate that with increasing length of employment the workload due to moral dilemmas, risk and responsibility and mental difficulties, gets reduced; on the other hand, the load resulting from work monotony is increased. Also the specialization degree affects the workload caused by the risk, responsibility and moral dilemmas. Noticeable here is the trend towards a reduction in the workload with increasing specialization degrees. Instead, the higher the scientific degree the higher the sense of load due to risk and responsibility with simultaneous decrease in the load due to work monotony.

Root canal penetration of a sodium hypochlorite mixture using sonic or ultrasonic activation.

PubMed

Sáinz-Pardo, Marta; Estevez, Roberto; Pablo, Óliver Valencia de; Rossi-Fedele, Giampiero; Cisneros, Rafael

2014-01-01

The purpose of this ex vivo study was to determine, in "open" and "closed" systems, whether the design has an influence on the penetration length of sodium hypochlorite mixed with a radiopaque contrast medium, measured in millimeters, when delivered using positive pressure (PP) and using sonic (SI) or passive ultrasonic (PUI) activation. Sixty single-rooted teeth were divided into two groups: open and closed systems (n=30). Root canal shaping was performed to a working length of 17 mm. The samples were divided into three sub-groups (n=10) according to irrigant delivery and activation: PP, and SI or PUI activation. By using radiographs, penetration length was measured, and vapor lock was assessed. For the closed group, the penetration distance means were: PP 15.715 (±0.898) mm, SI 16.299 (±0.738) mm and PUI 16.813 (±0.465) mm, with vapor lock occurring in 53.3% of the specimens. In the open group, penetration to 17 mm occurred in 97.6% of the samples, and no vapor lock occurred. Irrigant penetration and distribution evaluation using open and closed systems provide significantly different results. For closed systems, PUI is the most effective in delivering the irrigant to working length, followed by SI.

Comparison of working length control consistency between hand K-files and Mtwo NiTi rotary system.

PubMed

Krajczár, Károly; Varga, Enikő; Marada, Gyula; Jeges, Sára; Tóth, Vilmos

2016-04-01

The purpose of this study was to investigate the consistency of working length control between hand instrumentation in comparison to engine driven Mtwo nickel-titanium rotary files. Forty extracted maxillary molars were selected and divided onto two parallel groups. The working lengths of the mesiobuccal root canals were estimated. The teeth were fixed in a phantom head. The root canal preparation was carried out group 1 (n=20) with hand K-files, (VDW, Munich, Germany) and group 2 (n=20) with Mtwo instruments (VDW, Munich, Germany). Vestibulo-oral and mesio-distal directional x-ray images were taken before the preparation with #10 K-file, inserted into the mesiobuccal root canal to the working length, and after preparation with #25, #30 and #40 files. Working lenght changes were detected with measurements between the radiological apex and the instrument tips. In the Mtwo group a difference in the working competency (p<0.05) could be noticed only in the vestibulo-oral direction from #10 to #40 file. The hand instrument group showed a significant difference in working length competency for each larger file size (p<0.05) (ANOVA). Regression analysis in the hand instrumentation group indicated a working length decrease with a mean of 0,2 mm after each consecutive file size (p<0.01). The outcome of our trial indicated a high consistency in working length control for root canal preparation under simulated clinical condition using Mtwo rotary files. Mtwo NiTi rotary file did therefore proved to be more accurate in comparison to the conventional hand instrumentation. Working length, Mtwo, nickel-titanium, hand preparation, engine driven preparation.

Comparison of working length control consistency between hand K-files and Mtwo NiTi rotary system

PubMed Central

Krajczár, Károly; Varga, Enikő; Jeges, Sára; Tóth, Vilmos

2016-01-01

Background The purpose of this study was to investigate the consistency of working length control between hand instrumentation in comparison to engine driven Mtwo nickel-titanium rotary files. Material and Methods Forty extracted maxillary molars were selected and divided onto two parallel groups. The working lengths of the mesiobuccal root canals were estimated. The teeth were fixed in a phantom head. The root canal preparation was carried out group 1 (n=20) with hand K-files, (VDW, Munich, Germany) and group 2 (n=20) with Mtwo instruments (VDW, Munich, Germany). Vestibulo-oral and mesio-distal directional x-ray images were taken before the preparation with #10 K-file, inserted into the mesiobuccal root canal to the working length, and after preparation with #25, #30 and #40 files. Working lenght changes were detected with measurements between the radiological apex and the instrument tips. Results In the Mtwo group a difference in the working competency (p<0.05) could be noticed only in the vestibulo-oral direction from #10 to #40 file. The hand instrument group showed a significant difference in working length competency for each larger file size (p<0.05) (ANOVA). Regression analysis in the hand instrumentation group indicated a working length decrease with a mean of 0,2 mm after each consecutive file size (p<0.01). Conclusions The outcome of our trial indicated a high consistency in working length control for root canal preparation under simulated clinical condition using Mtwo rotary files. Mtwo NiTi rotary file did therefore proved to be more accurate in comparison to the conventional hand instrumentation. Key words:Working length, Mtwo, nickel-titanium, hand preparation, engine driven preparation. PMID:27034752

Large structures and tethers working group

NASA Technical Reports Server (NTRS)

Murphy, G.; Garrett, H.; Samir, U.; Barnett, A.; Raitt, J.; Sullivan, J.; Katz, I.

1986-01-01

The Large Structures and Tethers Working Group sought to clarify the meaning of large structures and tethers as they related to space systems. Large was assumed to mean that the characteristic length of the structure was greater than one of such relevant plasma characteristics as ion gyroradius or debey length. Typically, anything greater than or equal to the Shuttle dimensions was considered large. It was agreed that most large space systems that the tether could be better categorized as extended length, area, or volume structures. The key environmental interactions were then identified in terms of these three categories. In the following Working Group summary, these categories and the related interactions are defined in detail. The emphasis is on how increases in each of the three spatial dimensions uniquely determine the interactions with the near-Earth space environment. Interactions with the environments around the other planets and the solar wind were assumed to be similar or capable of being extrapolated from the near-Earth results. It should be remembered in the following that the effects on large systems do not just affect specific technologies but will quite likely impact whole missions. Finally, the possible effects of large systems on the plasma environment, although only briefly discussed, were felt to be of potentially great concern.

Shaping ability of NT Engine and McXim rotary nickel-titanium instruments in simulated root canals. Part 1.

PubMed

Thompson, S A; Dummer, P M

1997-07-01

The aim of this study was to determine the shaping ability of NT Engine and McXim nickel-titanium rotary instruments in simulated root canals. In all, 40 canals consisting of four different shapes in terms of angle and position of curvature were prepared by a combination of NT Engine and McXim instruments using the technique recommended by the manufacturer. Part 1 of this two-part report describes the efficacy of the instruments in terms of preparation time, instrument failure, canal blockages, loss of canal length and three-dimensional canal form. Overall, the mean preparation time for all canals was 6.01 min, with canal shape having a significant effect (P < 0.01) on the speed of preparation. One instrument fractured and only four instruments deformed, with most of the failures occurring in canals with curves which began 12 mm from the orifice, that is, in short acute curves. None of the canals became blocked with debris. Following preparation, 20 canals retained their original working length but 19 lost length and one gained in length; there were significant differences (P < 0.05) between the canal shapes in terms of mean loss of distance and in the category of distance change. Apical stops as determined from intracanal impressions were present in 37 of the canals; 16 were judged to be of good quality and 21 of poor quality. The canals were found to be smooth in the apical half of the canal in 33 specimens and in the coronal half of 39 specimens. All canals had good taper characteristics and 35 had good flow characteristics. Under the conditions of this study, NT Engine and McXim instruments prepared canals rapidly, with few deformations, no canal blockages and with minimal change in working length. The three-dimensional form of the canals demonstrated good flow and taper characteristics.

Diffusive processes in a stochastic magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, H.; Vlad, M.; Vanden Eijnden, E.

1995-05-01

The statistical representation of a fluctuating (stochastic) magnetic field configuration is studied in detail. The Eulerian correlation functions of the magnetic field are determined, taking into account all geometrical constraints: these objects form a nondiagonal matrix. The Lagrangian correlations, within the reasonable Corrsin approximation, are reduced to a single scalar function, determined by an integral equation. The mean square perpendicular deviation of a geometrical point moving along a perturbed field line is determined by a nonlinear second-order differential equation. The separation of neighboring field lines in a stochastic magnetic field is studied. We find exponentiation lengths of both signs describing,more » in particular, a decay (on the average) of any initial anisotropy. The vanishing sum of these exponentiation lengths ensures the existence of an invariant which was overlooked in previous works. Next, the separation of a particle`s trajectory from the magnetic field line to which it was initially attached is studied by a similar method. Here too an initial phase of exponential separation appears. Assuming the existence of a final diffusive phase, anomalous diffusion coefficients are found for both weakly and strongly collisional limits. The latter is identical to the well known Rechester-Rosenbluth coefficient, which is obtained here by a more quantitative (though not entirely deductive) treatment than in earlier works.« less

The association of telomere length and genetic variation in telomere biology genes.

PubMed

Mirabello, Lisa; Yu, Kai; Kraft, Peter; De Vivo, Immaculata; Hunter, David J; Prescott, Jennifer; Wong, Jason Y Y; Chatterjee, Nilanjan; Hayes, Richard B; Savage, Sharon A

2010-09-01

Telomeres cap chromosome ends and are critical for genomic stability. Many telomere-associated proteins are important for telomere length maintenance. Recent genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in genes encoding telomere-associated proteins (RTEL1 and TERT-CLPTM1) as markers of cancer risk. We conducted an association study of telomere length and 743 SNPs in 43 telomere biology genes. Telomere length in peripheral blood DNA was determined by Q-PCR in 3,646 participants from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial and Nurses' Health Study. We investigated associations by SNP, gene, and pathway (functional group). We found no associations between telomere length and SNPs in TERT-CLPTM1L or RTEL1. Telomere length was not significantly associated with specific functional groups. Thirteen SNPs from four genes (MEN1, MRE11A, RECQL5, and TNKS) were significantly associated with telomere length. The strongest findings were in MEN1 (gene-based P=0.006), menin, which associates with the telomerase promoter and may negatively regulate telomerase. This large association study did not find strong associations with telomere length. The combination of limited diversity and evolutionary conservation suggest that these genes may be under selective pressure. More work is needed to explore the role of genetic variants in telomere length regulation. Published 2010 Wiley-Liss, Inc.

Thermal characterization of microscale heat convection in rare-gas environment by a steady-state “hot wire” method

NASA Astrophysics Data System (ADS)

Gao, Jianshu; Xie, Danmei; Xiong, Yangheng; Yue, Yanan

2018-06-01

In this work, a steady-state “hot wire” method is developed to study thermal transport around a microwire in a rare-gas environment. The convection heat transfer coefficient (h) around a 25 µm platinum wire is determined to be from 14 W m‑2 K‑1 at 7 Pa to 629 W m‑2 K‑1 at atmospheric pressure. In the free-molecule regime, the Nusselt number is found to be inversely proportional to the Knudsen number, the slope of which is used to determine the slip length as 7.03 × 10‑4 m. In the transition regime, the slip length is found to be 20 times the wire diameter. Under a certain pressure, h decreases with increasing wire temperature, and this trend is more sensitive at high pressures.

Theoretical description of transverse measurements of polarization in optically-pumped Rb vapor cells

NASA Astrophysics Data System (ADS)

Dreiling, Joan; Tupa, Dale; Norrgard, Eric; Gay, Timothy

2012-06-01

In optical pumping of alkali-metal vapors, the polarization of the atoms is typically determined by probing along the entire length of the pumping beam, resulting in an averaged value of polarization over the length of the cell. Such measurements do not give any information about spatial variations of the polarization along the pump beam axis. Using a D1 probe beam oriented perpendicular to the pumping beam, we have demonstrated a heuristic method for determining the polarization along the pump beam's axis. Adapting a previously developed theory [1], we provide an analysis of the experiment which explains why this method works. The model includes the effects of Rb density, buffer gas pressure, and pump detuning. [4pt] [1] E.B. Norrgard, D. Tupa, J.M. Dreiling, and T.J. Gay, Phys. Rev. A 82, 033408 (2010).

An Empirical Investigation of Occupational Choice and Human Capital Accumulation at Mid-Life

ERIC Educational Resources Information Center

Xue, Yu

2010-01-01

Individual variation in labor supply can arise from more than just a choice among discrete occupation groups, especially given the joint process of wage determination and time allocation. Other factors can include differential preferences for earnings, the time length of work and other related occupational attributes. Using data from the Wisconsin…

Specifying initial stress for dynamic heterogeneous earthquake source models

USGS Publications Warehouse

Andrews, D.J.; Barall, M.

2011-01-01

Dynamic rupture calculations using heterogeneous stress drop that is random and self-similar with a power-law spatial spectrum have great promise of producing realistic ground-motion predictions. We present procedures to specify initial stress for random events with a target rupture length and target magnitude. The stress function is modified in the depth dimension to account for the brittle-ductile transition at the base of the seismogenic zone. Self-similar fluctuations in stress drop are tied in this work to the long-wavelength stress variation that determines rupture length. Heterogeneous stress is related to friction levels in order to relate the model to physical concepts. In a variant of the model, there are high-stress asperities with low background stress. This procedure has a number of advantages: (1) rupture stops naturally, not at artificial barriers; (2) the amplitude of short-wavelength fluctuations of stress drop is not arbitrary: the spectrum is fixed to the long-wavelength fluctuation that determines rupture length; and (3) large stress drop can be confined to asperities occupying a small fraction of the total rupture area, producing slip distributions with enhanced peaks.

Simulating Terrestrial Gamma-ray Flashes using SWORD (Invited)

NASA Astrophysics Data System (ADS)

Gwon, C.; Grove, J.; Dwyer, J. R.; Mattson, K.; Polaski, D.; Jackson, L.

2013-12-01

We report on simulations of the relativistic feedback discharges involved with the production of terrestrial gamma-ray flashes (TGFs). The simulations were conducted using Geant4 using the SoftWare for the Optimization of Radiation Detectors (SWORD) framework. SWORD provides a graphical interface for setting up simulations in select high-energy radiation transport engines. Using Geant4, we determine avalanche length, the energy spectrum of the electrons and gamma-rays as they leave the field region, and the feedback factor describing the degree to which the production of energetic particles is self-sustaining. We validate our simulations against previous work in order to determine the reliability of our results. This work is funded by the Office of Naval Research.

Dual-Band Band-Pass Filter with Fixed Low Band and Fluidically-Tunable High Band

PubMed Central

Park, Eiyong; Lim, Daecheon

2017-01-01

In this work, we present a dual-band band-pass filter with fixed low-band resonant frequency and tunable high-band resonant frequency. The proposed filter consists of two split-ring resonators (SRRs) with a stub and microfluidic channels. The lower resonant frequency is determined by the length of the SRR alone, whereas the higher resonant frequency is determined by the lengths of the SRR and the stub. Using this characteristic, we fix the lower resonant frequency by fixing the SRR length and tune the higher resonant frequency by controlling the stub length by injecting liquid metal in the microfluidic channel. We fabricated the filter on a Duroid substrate. The microfluidic channel was made from polydimethylsiloxane (PDMS), and eutectic gallium–indium (EGaIn) was used as the liquid metal. This filter operates in two states—with, and without, the liquid metal. In the state without the liquid metal, the filter has resonant frequencies at 1.85 GHz and 3.06 GHz, with fractional bandwidths of 4.34% and 2.94%, respectively; and in the state with the liquid metal, it has resonant frequencies at 1.86 GHz and 2.98 GHz, with fractional bandwidths of 4.3% and 2.95%, respectively. PMID:28813001

Rate-determining Step of Flap Endonuclease 1 (FEN1) Reflects a Kinetic Bias against Long Flaps and Trinucleotide Repeat Sequences.

PubMed

Tarantino, Mary E; Bilotti, Katharina; Huang, Ji; Delaney, Sarah

2015-08-21

Flap endonuclease 1 (FEN1) is a structure-specific nuclease responsible for removing 5'-flaps formed during Okazaki fragment maturation and long patch base excision repair. In this work, we use rapid quench flow techniques to examine the rates of 5'-flap removal on DNA substrates of varying length and sequence. Of particular interest are flaps containing trinucleotide repeats (TNR), which have been proposed to affect FEN1 activity and cause genetic instability. We report that FEN1 processes substrates containing flaps of 30 nucleotides or fewer at comparable single-turnover rates. However, for flaps longer than 30 nucleotides, FEN1 kinetically discriminates substrates based on flap length and flap sequence. In particular, FEN1 removes flaps containing TNR sequences at a rate slower than mixed sequence flaps of the same length. Furthermore, multiple-turnover kinetic analysis reveals that the rate-determining step of FEN1 switches as a function of flap length from product release to chemistry (or a step prior to chemistry). These results provide a kinetic perspective on the role of FEN1 in DNA replication and repair and contribute to our understanding of FEN1 in mediating genetic instability of TNR sequences. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Organizational citizenship behavior and work experience.

PubMed

Kegans, Loyd; McCamey, Randy B; Hammond, Honor

2012-01-01

The authors compared the relationship of elements of the Organizational Citizenship Behavior (OCB) and years of work experience of registered nurses in the state of Texas. Work experience research has shown a relationship between OCB and work experience through mediating roles of various work related characteristics does exist. Work experience is described as the overall length of time in an occupation or workforce. Civic virtue was the only element of organizational citizenship behavior to have a statistically significant correlation with years of work experience in this study. Other elements were found to have no statistically significant correlation with years of work experience. Further research should be undertaken to determine if correlations between these two constructs holds up when the population under study is further refined by job classification, such as management and staff, or industry segment.

Influence of resonator length on catastrophic optical damage in high-power AlGaInP broad-area lasers

NASA Astrophysics Data System (ADS)

Bou Sanayeh, Marwan

2017-05-01

The increasing importance of extracting high optical power out of semiconductor lasers motivated several studies in catastrophic optical damage (COD) level improvement. In this study, the influence of the resonator length in high-power broad-area (BA) AlGaInP lasers on COD is presented. For the analyses, several 638 nm AlGaInP 60 μm BA lasers from the same wafer were used. Resonator lengths of 900, 1200, 1500, and 1800 μm were compared. In order to independently examine the effect of the resonator length on the maximum power reached by the lasers before COD (PCOD), the lasers used are uncoated and unmounted, and PCOD under pulsed mode was determined. It was found that higher output powers and eventually higher PCOD can be achieved using longer resonators; however, it was also found that this is mainly useful when working at high output powers far away from the laser threshold, since the threshold current and slope efficiency worsen when the resonator length increases.

Two mechanisms of disorder-induced localization in photonic-crystal waveguides

NASA Astrophysics Data System (ADS)

García, P. D.; KiršanskÄ--, G.; Javadi, A.; Stobbe, S.; Lodahl, P.

2017-10-01

Unintentional but unavoidable fabrication imperfections in state-of-the-art photonic-crystal waveguides lead to the spontaneous formation of Anderson-localized modes thereby limiting slow-light propagation and its potential applications. On the other hand, disorder-induced cavities offer an approach to cavity-quantum electrodynamics and random lasing at the nanoscale. The key statistical parameter governing the disorder effects is the localization length, which together with the waveguide length determines the statistical transport of light through the waveguide. In a disordered photonic-crystal waveguide, the localization length is highly dispersive, and therefore, by controlling the underlying lattice parameters, it is possible to tune the localization of the mode. In the present work, we study the localization length in a disordered photonic-crystal waveguide using numerical simulations. We demonstrate two different localization regimes in the dispersion diagram where the localization length is linked to the density of states and the photon effective mass, respectively. The two different localization regimes are identified in experiments by recording the photoluminescence from quantum dots embedded in photonic-crystal waveguides.

The design of an fast Fourier filter for enhancing diagnostically relevant structures - endodontic files.

PubMed

Bruellmann, Dan; Sander, Steven; Schmidtmann, Irene

2016-05-01

The endodontic working length is commonly determined by electronic apex locators and intraoral periapical radiographs. No algorithms for the automatic detection of endodontic files in dental radiographs have been described in the recent literature. Teeth from the mandibles of pig cadavers were accessed, and digital radiographs of these specimens were obtained using an optical bench. The specimens were then recorded in identical positions and settings after the insertion of endodontic files of known sizes (ISO sizes 10-15). The frequency bands generated by the endodontic files were determined using fast Fourier transforms (FFTs) to convert the resulting images into frequency spectra. The detected frequencies were used to design a pre-segmentation filter, which was programmed using Delphi XE RAD Studio software (Embarcadero Technologies, San Francisco, USA) and tested on 20 radiographs. For performance evaluation purposes, the gauged lengths (measured with a caliper) of visible endodontic files were measured in the native and filtered images. The software was able to segment the endodontic files in both the samples and similar dental radiographs. We observed median length differences of 0.52 mm (SD: 2.76 mm) and 0.46 mm (SD: 2.33 mm) in the native and post-segmentation images, respectively. Pearson's correlation test revealed a significant correlation of 0.915 between the true length and the measured length in the native images; the corresponding correlation for the filtered images was 0.97 (p=0.0001). The algorithm can be used to automatically detect and measure the lengths of endodontic files in digital dental radiographs. Copyright © 2016 Elsevier Ltd. All rights reserved.

For money or service?: a cross-sectional survey of preference for financial versus non-financial rural practice characteristics among Ghanaian medical students.

PubMed

Johnson, Jennifer C; Nakua, Emmanuel; Dzodzomenyo, Mawuli; Agyei-Baffour, Peter; Gyakobo, Mawuli; Asabir, Kwesi; Kwansah, Janet; Kotha, S Rani; Snow, Rachel C; Kruk, Margaret E

2011-11-03

Health worker shortage and maldistribution are among the biggest threats to health systems in Africa. New medical graduates are prime targets for recruitment to deprived rural areas. However, little research has been done to determine the influence of workers' background and future plans on their preference for rural practice incentives and characteristics. The purpose of this study was to identify determinants of preference for rural job characteristics among fourth year medical students in Ghana. We asked fourth-year Ghanaian medical students to rank the importance of rural practice attributes including salary, infrastructure, management style, and contract length in considering future jobs. We used bivariate and multivariate ordinal logistic regression to estimate the association between attribute valuation and students' socio-demographic background, educational experience, and future career plans. Of 310 eligible fourth year medical students, complete data was available for 302 students (97%). Students considering emigration ranked salary as more important than students not considering emigration, while students with rural living experience ranked salary as less important than those with no rural experience. Students willing to work in a rural area ranked infrastructure as more important than students who were unwilling, while female students ranked infrastructure as less important than male students. Students who were willing to work in a rural area ranked management style as a more important rural practice attribute than those who were unwilling to work in a rural area. Students studying in Kumasi ranked contract length as more important than those in Accra, while international students ranked contract length as less important than Ghanaian students. Interventions to improve rural practice conditions are likely to be more persuasive than salary incentives to Ghanaian medical students who are willing to work in rural environments a priori. Policy experiments should test the impact of these interventions on actual uptake by students upon graduation.

For money or service? a cross-sectional survey of preference for financial versus non-financial rural practice characteristics among ghanaian medical students

PubMed Central

2011-01-01

Background Health worker shortage and maldistribution are among the biggest threats to health systems in Africa. New medical graduates are prime targets for recruitment to deprived rural areas. However, little research has been done to determine the influence of workers' background and future plans on their preference for rural practice incentives and characteristics. The purpose of this study was to identify determinants of preference for rural job characteristics among fourth year medical students in Ghana. Methods We asked fourth-year Ghanaian medical students to rank the importance of rural practice attributes including salary, infrastructure, management style, and contract length in considering future jobs. We used bivariate and multivariate ordinal logistic regression to estimate the association between attribute valuation and students' socio-demographic background, educational experience, and future career plans. Results Of 310 eligible fourth year medical students, complete data was available for 302 students (97%). Students considering emigration ranked salary as more important than students not considering emigration, while students with rural living experience ranked salary as less important than those with no rural experience. Students willing to work in a rural area ranked infrastructure as more important than students who were unwilling, while female students ranked infrastructure as less important than male students. Students who were willing to work in a rural area ranked management style as a more important rural practice attribute than those who were unwilling to work in a rural area. Students studying in Kumasi ranked contract length as more important than those in Accra, while international students ranked contract length as less important than Ghanaian students. Conclusions Interventions to improve rural practice conditions are likely to be more persuasive than salary incentives to Ghanaian medical students who are willing to work in rural environments a priori. Policy experiments should test the impact of these interventions on actual uptake by students upon graduation. PMID:22050704

Echinocyte shapes: bending, stretching, and shear determine spicule shape and spacing.

PubMed Central

Mukhopadhyay, Ranjan; Lim H W, Gerald; Wortis, Michael

2002-01-01

We study the shapes of human red blood cells using continuum mechanics. In particular, we model the crenated, echinocytic shapes and show how they may arise from a competition between the bending energy of the plasma membrane and the stretching/shear elastic energies of the membrane skeleton. In contrast to earlier work, we calculate spicule shapes exactly by solving the equations of continuum mechanics subject to appropriate boundary conditions. A simple scaling analysis of this competition reveals an elastic length Lambda(el), which sets the length scale for the spicules and is, thus, related to the number of spicules experimentally observed on the fully developed echinocyte. PMID:11916836

Lunar crater depths from orbiter IV long-focus photographs

USGS Publications Warehouse

Arthur, D.W.G.

1974-01-01

The paper presents method and results for the determination of the depths of more than 1900 small lunar craters from measures of shadows on the long-focus pictures obtained by Lunar Orbiter IV. The method for converting the measured shadow length into the true length in nature of the shadow hypotenuse is new and is applicable to other planetary bodies provided comparable spacecraft ephemerides are available. The measures were made with a simple surveyor's plotting scale on the standard Orbiter IV photographic enlargements. The results indicate that the smaller lunar (D < 30 km) craters are appreciably deeper than is indicated by earlier work using imagery obtained at terrestrial observatories. ?? 1974.

Structure of p73 DNA-binding domain tetramer modulates p73 transactivation

PubMed Central

Ethayathulla, Abdul S.; Tse, Pui-Wah; Monti, Paola; Nguyen, Sonha; Inga, Alberto; Fronza, Gilberto; Viadiu, Hector

2012-01-01

The transcription factor p73 triggers developmental pathways and overlaps stress-induced p53 transcriptional pathways. How p53-family response elements determine and regulate transcriptional specificity remains an unsolved problem. In this work, we have determined the first crystal structures of p73 DNA-binding domain tetramer bound to response elements with spacers of different length. The structure and function of the adaptable tetramer are determined by the distance between two half-sites. The structures with zero and one base-pair spacers show compact p73 DNA-binding domain tetramers with large tetramerization interfaces; a two base-pair spacer results in DNA unwinding and a smaller tetramerization interface, whereas a four base-pair spacer hinders tetramerization. Functionally, p73 is more sensitive to spacer length than p53, with one base-pair spacer reducing 90% of transactivation activity and longer spacers reducing transactivation to basal levels. Our results establish the quaternary structure of the p73 DNA-binding domain required as a scaffold to promote transactivation. PMID:22474346

Telomere length and fetal programming: A review of recent scientific advances.

PubMed

Whiteman, Valerie E; Goswami, Anjali; Salihu, Hamisu M

2017-05-01

We sought to synthesize a comprehensive literature review comprising recent research linking fetal programming to fetal telomere length. We also explored the potential effects fetal telomere length shortening has on fetal phenotypes. Utilizing the PubMed database as our primary search engine, we retrieved and reviewed 165 articles of published research. The inclusion criteria limited the articles to those that appeared within the last ten years, were pertinent to humans, and without restriction to language of publication. Our results showed that socio-demographic factors like age, sex, genetic inheritance, and acquired disease impact telomere length. Further, we found several maternal characteristics to be associated with fetal telomere length shortening, and these include maternal chemical exposure (eg, tobacco smoke), maternal stress during pregnancy, maternal nutritional and sleeping disorders during pregnancy as well as maternal disease status. Due to paucity of data, our review could not synthesize evidence directly linking fetal phenotypes to telomere length shortening. Although the research summarized in this review shows some association between determinants of intrauterine programming and fetal telomere length, there is still significant work that needs to be done to delineate the direct relationship of telomere attrition with specific fetal phenotypes. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Estimation of Flow Channel Parameters for Flowing Gas Mixed with Air in Atmospheric-pressure Plasma Jets

NASA Astrophysics Data System (ADS)

Yambe, Kiyoyuki; Saito, Hidetoshi

2017-12-01

When the working gas of an atmospheric-pressure non-equilibrium (cold) plasma flows into free space, the diameter of the resulting flow channel changes continuously. The shape of the channel is observed through the light emitted by the working gas of the atmospheric-pressure plasma. When the plasma jet forms a conical shape, the diameter of the cylindrical shape, which approximates the conical shape, defines the diameter of the flow channel. When the working gas flows into the atmosphere from the inside of a quartz tube, the gas mixes with air. The molar ratio of the working gas and air is estimated from the corresponding volume ratio through the relationship between the diameter of the cylindrical plasma channel and the inner diameter of the quartz tube. The Reynolds number is calculated from the kinematic viscosity of the mixed gas and the molar ratio. The gas flow rates for the upper limit of laminar flow and the lower limit of turbulent flow are determined by the corresponding Reynolds numbers estimated from the molar ratio. It is confirmed that the plasma jet length and the internal plasma length associated with strong light emission increase with the increasing gas flow rate until the rate for the upper limit of laminar flow and the lower limit of turbulent flow, respectively. Thus, we are able to explain the increasing trend in the plasma lengths with the diameter of the flow channel and the molar ratio by using the cylindrical approximation.

Effect of EDTA preparations on rotary root canal instrumentation.

PubMed

Whitbeck, Evan R; Swenson, Kelli; Tordik, Patricia A; Kondor, Shayne A; Webb, Terry D; Sun, Jirun

2015-01-01

The aim of this study was to evaluate whether rotary instrumentation using saline, EDTA 17% solution, or RC-Prep (Premier Dental, Philadelphia, PA) resulted in differences in root canal transportation. The secondary objective was to assess if instrumentation using these agents caused changes in the working length and canal volume. Moderately curved mesiobuccal roots of 24 maxillary molars were standardized in length and randomized into 1 control and 2 experimental groups. The canals were instrumented with 0.04 taper rotary files to size #30. All groups were irrigated with saline. Group 1 was also irrigated using EDTA 17% solution (Pulpdent Corp, Watertown, MA), and in group 2, RC-Prep was used. X-ray micro-computed tomographic scans and working length measurements were made before and after instrumentation. Three-dimensional models were created from the pre- and postinstrumentation scan data and compared for volume changes. Centroid points were calculated in cross-sectional slices of the canals, and transportation was determined by measuring the distance between the pre- and postinstrumentation points. The data were analyzed with 1-way analysis of variance (α = 0.05) and the Tukey post hoc test. Less transportation was observed in group 2 than in group 1 (P = .001) and the control group (P = .014). Transportation in group 1 and the control group was not significantly different. Canal volume in group 1 was increased relative to group 2 (P = .004) and the control group (P = .022). No significant differences in the working length were observed. The use of chelating agents during root canal instrumentation did not significantly increase apical transportation. Published by Elsevier Inc.

An improved model for teaching use of electronic apex locators.

PubMed

Tchorz, J P; Hellwig, E; Altenburger, M J

2012-04-01

To develop a simple, practical and inexpensive model, which enables the use of electronic apex locators (EALs) during pre-clinical and continuing education. Extracted teeth were placed in a mould and embedded in acrylic resin. The resin was applied in two consecutive steps to form a cavity around the root apices. A closable plastic tube serves as a valve, and a steel wire connects to the EAL. With its semi-closed reservoir for conductive fluids surrounding the root apices, the new model enables working length measurements of root canals using EALs. The model simulates the clinical situation for endodontic teaching purposes, as it allows working length determination of root canals as recommended. The measuring results of the EAL can be verified by radiography. At the same time, the roots are not directly visible and accessible to the user, allowing a precise evaluation and grading of the treatment. © 2011 International Endodontic Journal.

The width-tapered double cantilever beam for interlaminar fracture testing

NASA Technical Reports Server (NTRS)

Bascom, W. D.; Jensen, R. M.; Bullman, G. W.; Hunston, D. L.

1984-01-01

The width-tapered double-cantilever-beam (WTDCB) specimen configuration used to determine the Mode-I interlaminar fracture energy (IFE) of composites has special advantages for routine development work and for quality-assurance purposes. These advantages come primarily from the simplicity of testing and the fact that the specimen is designed for constant change in compliance with crack length, so that the computation of Mode-I IFE is independent of crack length. In this paper, a simplified technique for fabrication and testing WTDCB specimens is described. Also presented are the effects of fiber orientation and specimen dimensions, a comparison of data obtained using the WTDCB specimens and other specimen geometries, and comparison of data obtained at different laboratories. It is concluded that the WTDCB gives interlaminar Mode-I IFE essentially equal to other type specimens, and that it can be used for rapid screening in resin-development work and for quality assurance of composite materials.

Effects of alignment on the roll-over shapes of prosthetic feet.

PubMed

Hansen, Andrew

2008-12-01

Recent work suggests that a prosthetic ankle-foot component's roll-over shape - the effective rocker it conforms to between initial contact and opposite initial contact (the 'roll-over' interval of walking) - is closely linked to its final alignment in the prosthesis (as determined by a skilled prosthetist using heuristic techniques). If true, this information may help to determine the appropriate alignment for a lower limb prosthesis before it is built, or a priori. Knowledge is needed for future models that will incorporate the roll-over shape including the relative effect of alignment on the roll-over shape's radius of curvature and arc length. The purpose of this study was to evaluate the hypotheses that: (i) Changes in prosthesis alignment alter the position and orientation of a foot's roll-over shape in prosthesis-based coordinates, and (ii) these changes occur without changing the radius of curvature or arc length of the roll-over shape. To examine the hypotheses, this study examined the effects of nine alignment settings on the roll-over shapes of two prosthetic feet. The idea that alignment changes move and rotate roll-over shapes of prosthetic feet in prosthesis coordinates is supported by this work, but the hypothesis that the radius of curvature and arc length do not change for different alignments is not strongly supported by the data. A revised approach is presented that explains some of the changes to the roll-over shape parameters due to changes in rotational alignment.

Critical assessment of precracked specimen configuration and experimental test variables for stress corrosion testing of 7075-T6 aluminum alloy plate

NASA Technical Reports Server (NTRS)

Domack, M. S.

1985-01-01

A research program was conducted to critically assess the effects of precracked specimen configuration, stress intensity solutions, compliance relationships and other experimental test variables for stress corrosion testing of 7075-T6 aluminum alloy plate. Modified compact and double beam wedge-loaded specimens were tested and analyzed to determine the threshold stress intensity factor and stress corrosion crack growth rate. Stress intensity solutions and experimentally determined compliance relationships were developed and compared with other solutions available in the literature. Crack growth data suggests that more effective crack length measurement techniques are necessary to better characterize stress corrosion crack growth. Final load determined by specimen reloading and by compliance did not correlate well, and was considered a major source of interlaboratory variability. Test duration must be determined systematically, accounting for crack length measurement resolution, time for crack arrest, and experimental interferences. This work was conducted as part of a round robin program sponsored by ASTM committees G1.06 and E24.04 to develop a standard test method for stress corrosion testing using precracked specimens.

Performance of quantum Monte Carlo for calculating molecular bond lengths

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cleland, Deidre M., E-mail: deidre.cleland@csiro.au; Per, Manolo C., E-mail: manolo.per@csiro.au

2016-03-28

This work investigates the accuracy of real-space quantum Monte Carlo (QMC) methods for calculating molecular geometries. We present the equilibrium bond lengths of a test set of 30 diatomic molecules calculated using variational Monte Carlo (VMC) and diffusion Monte Carlo (DMC) methods. The effect of different trial wavefunctions is investigated using single determinants constructed from Hartree-Fock (HF) and Density Functional Theory (DFT) orbitals with LDA, PBE, and B3LYP functionals, as well as small multi-configurational self-consistent field (MCSCF) multi-determinant expansions. When compared to experimental geometries, all DMC methods exhibit smaller mean-absolute deviations (MADs) than those given by HF, DFT, and MCSCF.more » The most accurate MAD of 3 ± 2 × 10{sup −3} Å is achieved using DMC with a small multi-determinant expansion. However, the more computationally efficient multi-determinant VMC method has a similar MAD of only 4.0 ± 0.9 × 10{sup −3} Å, suggesting that QMC forces calculated from the relatively simple VMC algorithm may often be sufficient for accurate molecular geometries.« less

Analysis of bulk arrival queueing system with batch size dependent service and working vacation

NASA Astrophysics Data System (ADS)

Niranjan, S. P.; Indhira, K.; Chandrasekaran, V. M.

2018-04-01

This paper concentrates on single server bulk arrival queue system with batch size dependent service and working vacation. The server provides service in two service modes depending upon the queue length. The server provides single service if the queue length is at least `a'. On the other hand the server provides fixed batch service if the queue length is at least `k' (k > a). Batch service is provided with some fixed batch size `k'. After completion of service if the queue length is less than `a' then the server leaves for working vacation. During working vacation customers are served with lower service rate than the regular service rate. Service during working vacation also contains two service modes. For the proposed model probability generating function of the queue length at an arbitrary time will be obtained by using supplementary variable technique. Some performance measures will also be presented with suitable numerical illustrations.

Hamstring muscle length and lumbar lordosis in subjects with different lifestyle and work setting: comparison between individuals with and without chronic low back pain.

PubMed

Arab, Amir Massoud; Nourbakhsh, Mohammad Reza

2014-01-01

Shortened hamstring muscle length has been noted in persons with low back pain (LBP). Prolonged sitting postures, such as those adopted during different work settings and sedentary lifestyle has been associated with hamstring shortness and LBP. The purpose of this study was to investigate the effect of lifestyle and work setting on hamstring length and lumbar lordosis in subjects with and without LBP and to identify the relationship between hamstring muscles length and lumbar lordosis in individuals with different lifestyle and work setting. A total of 508 subjects between the ages of 20 and 65 were selected. Subjects were categorized into two groups of individuals with and without LBP. A questionnaire was used to obtain information about the subjects' lifestyle and work setting. Hamstring muscle length and lumbar lordosis were measured in all subjects. The results showed no significant difference in the number of subjects with different work setting or lifestyle in individuals with and without LBP. Hamstring muscle length or lumbar lordosis was not affected by type of work setting and lifestyle. Our data showed significant difference in hamstring length and no significant difference in lumbar lordosis between subjects with and without LBP in all categories. Lumbar lordosis was not different between individuals with and without hamstring tightness in normal and LBP subjects with different work setting and lifestyle. The findings of this study did not support the assumption that work setting and sedentary lifestyle would lead to hamstring tightness in subjects with LBP. It seems that work setting and lifestyle was not a contributing factor for hamstring tightness in subjects with LBP.

A novel gene network inference algorithm using predictive minimum description length approach.

PubMed

Chaitankar, Vijender; Ghosh, Preetam; Perkins, Edward J; Gong, Ping; Deng, Youping; Zhang, Chaoyang

2010-05-28

Reverse engineering of gene regulatory networks using information theory models has received much attention due to its simplicity, low computational cost, and capability of inferring large networks. One of the major problems with information theory models is to determine the threshold which defines the regulatory relationships between genes. The minimum description length (MDL) principle has been implemented to overcome this problem. The description length of the MDL principle is the sum of model length and data encoding length. A user-specified fine tuning parameter is used as control mechanism between model and data encoding, but it is difficult to find the optimal parameter. In this work, we proposed a new inference algorithm which incorporated mutual information (MI), conditional mutual information (CMI) and predictive minimum description length (PMDL) principle to infer gene regulatory networks from DNA microarray data. In this algorithm, the information theoretic quantities MI and CMI determine the regulatory relationships between genes and the PMDL principle method attempts to determine the best MI threshold without the need of a user-specified fine tuning parameter. The performance of the proposed algorithm was evaluated using both synthetic time series data sets and a biological time series data set for the yeast Saccharomyces cerevisiae. The benchmark quantities precision and recall were used as performance measures. The results show that the proposed algorithm produced less false edges and significantly improved the precision, as compared to the existing algorithm. For further analysis the performance of the algorithms was observed over different sizes of data. We have proposed a new algorithm that implements the PMDL principle for inferring gene regulatory networks from time series DNA microarray data that eliminates the need of a fine tuning parameter. The evaluation results obtained from both synthetic and actual biological data sets show that the PMDL principle is effective in determining the MI threshold and the developed algorithm improves precision of gene regulatory network inference. Based on the sensitivity analysis of all tested cases, an optimal CMI threshold value has been identified. Finally it was observed that the performance of the algorithms saturates at a certain threshold of data size.

Medial prefrontal lesions in mice impair sustained attention but spare maintenance of information in working memory.

PubMed

Kahn, Julia B; Ward, Ryan D; Kahn, Lora W; Rudy, Nicole M; Kandel, Eric R; Balsam, Peter D; Simpson, Eleanor H

2012-10-16

Working memory and attention are complex cognitive functions that are disrupted in several neuropsychiatric disorders. Mouse models of such human diseases are commonly subjected to maze-based tests that can neither distinguish between these cognitive functions nor isolate specific aspects of either function. Here, we have adapted a simple visual discrimination task, and by varying only the timing of events within the same task construct, we are able to measure independently the behavioral response to increasing attentional demand and increasing length of time that information must be maintained in working memory. We determined that mPFC lesions in mice impair attention but not working memory maintenance.

The Magic Number 70 (Plus or Minus 20): Variables Determining Performance in the Rodent Odor Span Task

ERIC Educational Resources Information Center

April, L. Brooke; Bruce, Katherine; Galizio, Mark

2013-01-01

The olfactory span task (OST) uses an incrementing non-matching to sample procedure such that the number of stimuli to remember increases during the session. The number of consecutive correct responses (span length) and percent correct as a function of the memory load have been viewed as defining rodent working memory capacity limitations in…

Costs of logging thinnings and a clearcutting in Appalachia using a truck-mounted crane

Treesearch

Raymond L. Sarles; Kenneth R. Whitenack

1984-01-01

Four timber cutting treatments - three levels of thinning and a clearcutting - were applied on 60-year-old mountain stands of Allegheny hardwoods. The stands were logged by a three-man crew using chain saws and a truck-mounted crane. Logging operations were studied, and production rates determined for tree-length logs decked at roadside. Work efficiency and...

Contribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle

PubMed Central

Chung, Charles S; Granzier, Henk L

2011-01-01

It remains to be established to what degree titin and the extracellular matrix (ECM) contribute to passive pressure in the left ventricle (LV). Thus, we aimed to elucidate the contribution of major molecular determinants of passive pressure in the normal mouse LV. Furthermore, we determined the working sarcomere length (SL) range of the LV to bridge our findings to earlier work in skinned muscle fibers. We utilized Frank-Starling type protocols to obtain diastolic pressure-volume relationships (PVR) in Langendorff perfused isolated LVs. To quantify the molecular contribution of titin and ECM, we innovated on methods of fiber mechanics to chemically permeabilize intact LVs and measure a fully passive PVR. To differentially dissect the contributions of the ECM and titin, we utilized myofilament extraction techniques in permeabilized LVs, measuring passive PVRs at each stage in the protocol. Myofilament extraction suggests that titin contributes ~80% of passive pressures in the heart. Langendorff perfusion was also used to chemically fix passive and BaCl2 activated hearts at specific volumes to determine that the maximal working SL range of the midwall LV fibers is approximately 1.8-2.2 μm. A model of the passive SL-Volume relationship was then used to estimate the pressure-SL relationships, indicating that the ECM contribution does not exceed titin's contribution until large volumes with SLs>~2.2μm. In conclusion, within physiological volumes titin is the dominant contributor to LV passive pressure, and ECM-based pressures dominates at larger volumes. PMID:21255582

Electron Temperature Gradient Scale Measurements in ICRF Heated Plasmas at Alcator C-Mod

NASA Astrophysics Data System (ADS)

Houshmandyar, Saeid; Phillips, Perry E.; Rowan, William L.; Howard, Nathaniel T.; Greenwald, Martin

2016-10-01

It is generally believed that the temperature gradient is a driving mechanism for the turbulent transport in hot and magnetically confined plasmas. A feature of many anomalous transport models is the critical threshold value (LC) for the gradient scale length, above which both the turbulence and the heat transport increases. This threshold is also predicted by the recent multi-scale gyrokinetic simulations, which are focused on addressing the electron (and ion) heat transport in tokamaks. Recently, we have established an accurate technique (BT-jog) to directly measure the electron temperature gradient scale length (LTe =Te / ∇T) profile, using a high-spatial resolution radiometer-based electron cyclotron emission (ECE) diagnostic. For the work presented here, electrons are heated by ion cyclotron range of frequencies (ICRF) through minority heating in L-mode plasmas at different power levels, TRANSP runs determine the electron heat fluxes and the scale lengths are measured through the BT-jog technique. Furthermore, the experiment is extended for different plasma current and electron densities by which the parametric dependence of LC on magnetic shear, safety factor and density will be investigated. This work is supported by U.S. DoE OFES, under Award No. DE-FG03-96ER-54373.

Comparing the Relationship Between Age and Length of Disability Across Common Chronic Conditions

PubMed Central

Jetha, Arif; Besen, Elyssa; Smith, Peter M.

2016-01-01

Objective: The aim of this study was to compare the association between age and disability length across common chronic conditions. Methods: Analysis of 39,915 nonwork-related disability claims with a diagnosis of arthritis, diabetes, hypertension, coronary artery disease, depression, low back pain, chronic pulmonary disease, or cancer. Ordinary least squares regression models examined age-length of disability association across chronic conditions. Results: Arthritis (76.6 days), depression (63.2 days), and cancer (64.9 days) were associated with longest mean disability lengths; hypertension was related to shortest disability lengths (41.5 days). Across chronic conditions, older age was significantly associated with longer work disability. The age–length of disability association was most significant for chronic pulmonary disease and cancer. The relationship between age and length of work disability was linear among most chronic conditions. Conclusions: Work disability prevention strategies should consider both employee age and chronic condition diagnosis. PMID:27164446

[Modulating variables of work disability in depressive disorders].

PubMed

Catalina Romero, C; Cabrera Sierra, M; Sainz Gutiérrez, J C; Barrenechea Albarrán, J L; Madrid Conesa, A; Calvo Bonacho, E

2011-01-01

To describe the duration of sickness absence in unipolar depression and to determine the relationship of demographic, job-related and clinical variables with length of temporary work disability in depressive disorders. Prospective observational study. A total of 1,292 subjects with depressive disorder diagnosis (ICD-9-CM) were selected claiming sick leave in an Occupational Diseases and Accident sat Work Insurance Scheme (sampling on successive occasions). Descriptive analyses of sickness absence duration, and bivariate (median test) and multivariate analysis (logistic regression) were performed to find relationships between demographic, job-related and clinical variables. Mean duration of sickness absence episodes due to a depressive disorder was 120 days. After multivariate analyses, female sex (p < 0.01), higher age (p < 0.01), lower educational level (p < 0.01), method of payment according to whether self-employed or unemployed workers (p < 0.01) and being referred to both psychiatrist and psychologist (p < 0.01) remained significantly associated with sick leave length. These findings confirm a strong association of depression with long periods of work disability and high absenteeism, and also suggest the need for improvements in functional ability assessment and promotion, treatment and referral of depressed patients. Copyright © 2010 SECA. Published by Elsevier Espana. All rights reserved.

Optimal muscle fascicle length and tendon stiffness for maximising gastrocnemius efficiency during human walking and running.

PubMed

Lichtwark, G A; Wilson, A M

2008-06-21

Muscles generate force to resist gravitational and inertial forces and/or to undertake work, e.g. on the centre of mass. A trade-off in muscle architecture exists in muscles that do both; the fibres should be as short as possible to minimise activation cost but long enough to maintain an appropriate shortening velocity. Energetic cost is also influenced by tendon compliance which modulates the timecourse of muscle mechanical work. Here we use a Hill-type muscle model of the human medial gastrocnemius to determine the muscle fascicle length and Achilles tendon compliance that maximise efficiency during the stance phase of walking (1.2m/s) and running (3.2 and 3.9 m/s). A broad range of muscle fascicle lengths (ranging from 45 to 70 mm) and tendon stiffness values (150-500 N/mm) can achieve close to optimal efficiency at each speed of locomotion; however, efficient walking requires shorter muscle fascicles and a more compliant tendon than running. The values that maximise efficiency are within the range measured in normal populations. A non-linear toe-region region of the tendon force-length properties may further influence the optimal values, requiring a stiffer tendon with slightly longer muscle fascicles; however, it does not alter the main results. We conclude that muscle fibre length and tendon compliance combinations may be tuned to maximise efficiency under a given gait condition. Efficiency is maximised when the required volume of muscle is minimised, which may also help reduce limb inertia and basal metabolic costs.

Ambient temperature effects on growth of milkfish (Chanos chanos) at aquaculture scale in Blanakan, West Java

NASA Astrophysics Data System (ADS)

A'yun, Q.; Takarina, N. D.

2017-07-01

Growth and survival of fishes can be influenced by temperature [1]. Variation among size like weight and length could be the preference how temperature works on growth of fishes [2]. This could be key factor in determining in production as well as market demand since people like heavy and large fishes. The main purpose of this study was to determine the effects of temperature on the growth of milkfish (Chanos Chanos) on weight and length parameters in fish farms Blanakan. This study conducted to assess the optimal temperature for the growth of fish of different sizes to optimize the culture conditions for raising milkfishes in scale cultivation in Blanakan, West Java. Milkfishes were reared in the aquaculture Blanakan ponds because they can adapt very well. The weight and length of milkfishes were measured together with water temperature. The results showed the temperature min (tmin) and max (tmax) were ranged from 29-35 °C. Based on the result, there were significant differences in mean weight (p = 0.00) between temperature with the fish reared in tmax group having the lowest mean weight (99.87±11.51 g) and fish reared in tmin group having the highest mean weight (277.17±33.76 g). Likewise, the significant differences were also observed in mean length (p = 0.00) between temperature with the fish reared in tmax group having the lowest mean length (176.50±12.50 mm) and fish reared in tmin group having the highest mean length (183.60±23.86 mm). Therefore, this paper confirmed the significant effects of temperature on the fish growth reared in aquaculture ponds. More, maintaining aquaculture to lower temperature can be considered as way to keep growth of milkfish well.

The impact analysis of the connecting pipe length and diameter on the operation of a piston hybrid power machine of positive displacement with gas suction capacity

NASA Astrophysics Data System (ADS)

Shcherba, V. E.; Grigoriev, A. V.; Averyanov, G. S.; Surikov, V. I.; Vedruchenko, V. P.; Galdin, N. S.; Trukhanova, D. A.

2017-08-01

The article analyzes the impact of the connecting liquid pipe length and diameter on consumables and power characteristics of the piston hybrid power machine with gas suction capacity. The following operating characteristics of the machine were constructed and analyzed: the average height of the liquid column in the jacket space; instantaneous velocity and height of the liquid column in the jacket space; the relative height of the liquid column in the jacket space; volumetric efficiency; indicator isothermal efficiency; flowrate in the pump section; relative pressure losses during suction; relative flowrate. The dependence of the instantaneous pressure in the work space and the suction space of the compressor section on the rotation angle of the crankshaft is determined for different values of the length and diameter of the connecting pipeline.

Structure-based inhibitors of tau aggregation

NASA Astrophysics Data System (ADS)

Seidler, P. M.; Boyer, D. R.; Rodriguez, J. A.; Sawaya, M. R.; Cascio, D.; Murray, K.; Gonen, T.; Eisenberg, D. S.

2018-02-01

Aggregated tau protein is associated with over 20 neurological disorders, which include Alzheimer's disease. Previous work has shown that tau's sequence segments VQIINK and VQIVYK drive its aggregation, but inhibitors based on the structure of the VQIVYK segment only partially inhibit full-length tau aggregation and are ineffective at inhibiting seeding by full-length fibrils. Here we show that the VQIINK segment is the more powerful driver of tau aggregation. Two structures of this segment determined by the cryo-electron microscopy method micro-electron diffraction explain its dominant influence on tau aggregation. Of practical significance, the structures lead to the design of inhibitors that not only inhibit tau aggregation but also inhibit the ability of exogenous full-length tau fibrils to seed intracellular tau in HEK293 biosensor cells into amyloid. We also raise the possibility that the two VQIINK structures represent amyloid polymorphs of tau that may account for a subset of prion-like strains of tau.

Does neighborhood size really cause the word length effect?

PubMed

Guitard, Dominic; Saint-Aubin, Jean; Tehan, Gerald; Tolan, Anne

2018-02-01

In short-term serial recall, it is well-known that short words are remembered better than long words. This word length effect has been the cornerstone of the working memory model and a benchmark effect that all models of immediate memory should account for. Currently, there is no consensus as to what determines the word length effect. Jalbert and colleagues (Jalbert, Neath, Bireta, & Surprenant, 2011a; Jalbert, Neath, & Surprenant, 2011b) suggested that neighborhood size is one causal factor. In six experiments we systematically examined their suggestion. In Experiment 1, with an immediate serial recall task, multiple word lengths, and a large pool of words controlled for neighborhood size, the typical word length effect was present. In Experiments 2 and 3, with an order reconstruction task and words with either many or few neighbors, we observed the typical word length effect. In Experiment 4 we tested the hypothesis that the previous abolition of the word length effect when neighborhood size was controlled was due to a confounded factor: frequency of orthographic structure. As predicted, we reversed the word length effect when using short words with less frequent orthographic structures than the long words, as was done in both of Jalbert et al.'s studies. In Experiments 5 and 6, we again observed the typical word length effect, even if we controlled for neighborhood size and frequency of orthographic structure. Overall, the results were not consistent with the predictions of Jalbert et al. and clearly showed a large and reliable word length effect after controlling for neighborhood size.

Memory for tonal pitches: a music-length effect hypothesis.

PubMed

Akiva-Kabiri, Lilach; Vecchi, Tomaso; Granot, Roni; Basso, Demis; Schön, Daniele

2009-07-01

One of the most studied effects of verbal working memory (WM) is the influence of the length of the words that compose the list to be remembered. This work aims to investigate the nature of musical WM by replicating the word length effect in the musical domain. Length and rate of presentation were manipulated in a recognition task of tone sequences. Results showed significant effects for both factors (length and presentation rate) as well as their interaction, suggesting the existence of different strategies (e.g., chunking and rehearsal) for the immediate memory of musical information, depending upon the length of the sequences.

Nanomechanics modeling of carbon nanotubes interacting with surfaces in various configurations

NASA Astrophysics Data System (ADS)

Wu, Yu-Chiao

Carbon nanotubes (CNTs) have been widely used as potential components in reported nanoelectromechanical (NEM) devices due to their excellent mechanical and electrical properties. This thesis models the experiments by the continuum mechanics in two distinct scenarios. In the first situation, measurements are made of CNT configurations after manipulations. Modeling is then used to determine the interfacial properties during the manipulation which led to the observed configuration. This technique is used to determine the shear stress between a SWNT bundle and other materials. During manipulation, a SWNT bundle slipped on two micro-cantilevers. According to the slack due to the slippage after testing and the device configuration, the shear stress between a SWNT bundle and other materials can be determined. In another model, the work of adhesion was determined on two accidentally fabricated devices. Through the configuration of two SWNT adhered bundles and the force-distance curves measured by an atomic force microscope (AFM), modeling was used to determine the work of adhesion between two bundles and the shear stress at the SWNT-substrate interface. In the second situation, modeling is used in a more traditional fashion to make theoretical predictions as to how a device will operate. Using this technique, the actuation mechanism of a single-trench SWNT-based switch was investigated. During the actuation, the deflection-induced tension causes the SWNT bundle to slip on both platforms and to be partially peeled from two side recessed electrodes. These effects produce a slack which reduces the threshold voltages subsequent to the first actuation. The result shows excellent agreement between the theory and the measurement. Furthermore, the operation of a double-trenched SWNT-based switch was investigated. A slack is produced in the 1st actuated trench region by the slip and peeling effects. This slack reduces the 2nd actuation voltage in the neighbor trench. Finally, the adhesive slip process at the SWNT-substrate interface was simulated. The result shows that the force for slip of a SWNT remains constant for lengths less than about 240 nm. Beyond that length, increasing the contact length causes increase the force for slippage. This phenomenon agrees well with reported experiments.

Effect of apical size and taper on volume of irrigant delivered at working length with apical negative pressure at different root curvatures.

PubMed

de Gregorio, Cesar; Arias, Ana; Navarrete, Natalia; Del Rio, Veronica; Oltra, Enrique; Cohenca, Nestor

2013-01-01

The purpose of this investigation was to determine the effect that apical preparation size and preparation taper have on the volume of irrigant delivered at the working length for different canal curvatures using apical negative pressure irrigation. One hundred fifty-five human teeth (55 maxillary canines and 100 mandibular molars) were used in this study. Root canals were prepared with rotary instruments to a size 35.04 and separated into 3 experimental groups according to their degree of curvature: group A (n = 50) included canal curvatures ranging from 0° to 10°, group B (n = 50) from 11° to 30°, and group C (n = 50) from 31° to 65°. Samples of each curvature group were further randomized to experimental subgroups according to the apical size and taper as follow: 35.06, 40.04, 40.06, 45.04, and 45.06. The apical third was irrigated using a microcannula and the volume of NaOCl suctioned at the working length under negative pressure was measured over a period of 30 seconds using a fluid recovery trap. Positive controls consisted of measuring the maximum volume of 5.25% NaOCl capable of being suctioned by the microcannula from an open glass vial over 30 seconds. Negative control was the volume of irrigant aspirated by the microcannula with a preparation size of 25.04 over 30 seconds. The volume of irrigant was significantly greater when the apical preparation size increased from 35.06 to 40.04. As the apical preparation taper increased further from 40.04 to 40.06, the volume of irrigant significantly improved in group B, but it was not significant in group A. Apical preparation sizes greater than 40.06 did not show an increase of the volume of irrigant aspirated. The degree of root canal curvature decreased the volume of irrigant at the working length for a given apical size and taper. An apical preparation of 40.06 significantly increased the volume and exchange of irrigant at the working length regardless of curvature. Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Shared genetic determinants of axial length and height in children: the Guangzhou twin eye study.

PubMed

Zhang, Jian; Hur, Yoon-Mi; Huang, Wenyong; Ding, Xiaohu; Feng, Ke; He, Mingguang

2011-01-01

To describe the association between axial length (AL) and height and to estimate the extent to which shared genetic or environmental factors influence this covariance. Study participants were recruited from the Guangzhou Twin Registry. Axial length was measured using partial coherence laser interferometry. Height was measured with the participants standing without shoes. We computed twin pairwise correlations and cross-twin cross-trait correlations between AL and height for monozygotic and dizygotic twins and performed model-fitting analyses using a multivariate Cholesky model. The right eye was arbitrarily selected to represent AL of participants. Five hundred sixty-five twin pairs (359 monozygotic and 206 dizygotic) aged 7 to 15 years were available for analysis. Phenotypic correlation between AL and height was 0.46 but decreased to 0.19 after adjusting for age, sex, and age × sex interaction. Bivariate Cholesky model-fitting analyses revealed that 89% of phenotypic correlation was due to shared genetic factors and 11% was due to shared random environmental factors, which includes measurement error. Covariance of AL and height is largely attributable to shared genes. Given that AL is a key determinant of myopia, further work is needed to confirm gene sharing between myopia and stature.

Recurrence Quantification Analysis of Sentence-Level Speech Kinematics.

PubMed

Jackson, Eric S; Tiede, Mark; Riley, Michael A; Whalen, D H

2016-12-01

Current approaches to assessing sentence-level speech variability rely on measures that quantify variability across utterances and use normalization procedures that alter raw trajectory data. The current work tests the feasibility of a less restrictive nonlinear approach-recurrence quantification analysis (RQA)-via a procedural example and subsequent analysis of kinematic data. To test the feasibility of RQA, lip aperture (i.e., the Euclidean distance between lip-tracking sensors) was recorded for 21 typically developing adult speakers during production of a simple utterance. The utterance was produced in isolation and in carrier structures differing just in length or in length and complexity. Four RQA indices were calculated: percent recurrence (%REC), percent determinism (%DET), stability (MAXLINE), and stationarity (TREND). Percent determinism (%DET) decreased only for the most linguistically complex sentence; MAXLINE decreased as a function of linguistic complexity but increased for the longer-only sentence; TREND decreased as a function of both length and linguistic complexity. This research note demonstrates the feasibility of using RQA as a tool to compare speech variability across speakers and groups. RQA offers promise as a technique to assess effects of potential stressors (e.g., linguistic or cognitive factors) on the speech production system.

Recurrence Quantification Analysis of Sentence-Level Speech Kinematics

PubMed Central

Tiede, Mark; Riley, Michael A.; Whalen, D. H.

2016-01-01

Purpose Current approaches to assessing sentence-level speech variability rely on measures that quantify variability across utterances and use normalization procedures that alter raw trajectory data. The current work tests the feasibility of a less restrictive nonlinear approach—recurrence quantification analysis (RQA)—via a procedural example and subsequent analysis of kinematic data. Method To test the feasibility of RQA, lip aperture (i.e., the Euclidean distance between lip-tracking sensors) was recorded for 21 typically developing adult speakers during production of a simple utterance. The utterance was produced in isolation and in carrier structures differing just in length or in length and complexity. Four RQA indices were calculated: percent recurrence (%REC), percent determinism (%DET), stability (MAXLINE), and stationarity (TREND). Results Percent determinism (%DET) decreased only for the most linguistically complex sentence; MAXLINE decreased as a function of linguistic complexity but increased for the longer-only sentence; TREND decreased as a function of both length and linguistic complexity. Conclusions This research note demonstrates the feasibility of using RQA as a tool to compare speech variability across speakers and groups. RQA offers promise as a technique to assess effects of potential stressors (e.g., linguistic or cognitive factors) on the speech production system. PMID:27824987

Implementation of a flow-dependent background error correlation length scale formulation in the NEMOVAR OSTIA system

NASA Astrophysics Data System (ADS)

Fiedler, Emma; Mao, Chongyuan; Good, Simon; Waters, Jennifer; Martin, Matthew

2017-04-01

OSTIA is the Met Office's Operational Sea Surface Temperature (SST) and Ice Analysis system, which produces L4 (globally complete, gridded) analyses on a daily basis. Work is currently being undertaken to replace the original OI (Optimal Interpolation) data assimilation scheme with NEMOVAR, a 3D-Var data assimilation method developed for use with the NEMO ocean model. A dual background error correlation length scale formulation is used for SST in OSTIA, as implemented in NEMOVAR. Short and long length scales are combined according to the ratio of the decomposition of the background error variances into short and long spatial correlations. The pre-defined background error variances vary spatially and seasonally, but not on shorter time-scales. If the derived length scales applied to the daily analysis are too long, SST features may be smoothed out. Therefore a flow-dependent component to determining the effective length scale has also been developed. The total horizontal gradient of the background SST field is used to identify regions where the length scale should be shortened. These methods together have led to an improvement in the resolution of SST features compared to the previous OI analysis system, without the introduction of spurious noise. This presentation will show validation results for feature resolution in OSTIA using the OI scheme, the dual length scale NEMOVAR scheme, and the flow-dependent implementation.

Characteristics of ocean-reflected short radar pulses with application to altimetry and surface roughness determination

NASA Technical Reports Server (NTRS)

Miller, L. S.; Hayne, G. S.

1972-01-01

Current work related to geodetic altimetry is summarized. Special emphasis is placed on the effects of pulse length on both altimetry and sea-state estimation. Some discussion is also given of system tradeoff parameters and sea truth requirements to support scattering studies. The problem of analyzing signal characteristics and altimeter waveforms arising from rough surface backscattering is also considered.

Evaluation of a small diameter baffled culvert for passing juvenile salmonids.

Treesearch

Mason D. Bryant

1981-01-01

A 90-cm-diameter culvert with off-set baffles was set at a 10-percent gradient in an artificial stream channel on Admiralty Island, Alaska. Coho salmon, Dolly Varden char, and cutthroat trout, all less than 120-mm fork length, were able to move up the 9-m culvert. Additional work is needed to determine an upper discharge limit and to evaluate field installations.

Development of flow in a square mini-channel: Effect of flow oscillation

NASA Astrophysics Data System (ADS)

Lobo, Oswald Jason; Chatterjee, Dhiman

2018-04-01

In this research paper, we present a numerical prediction of steady and fully oscillatory flows in a square mini-channel connected between two plenums. Flow separation occurs at the contraction of the plenum into the channel which causes an asymmetry in the development of flow in the entrance region. The entrance length and recirculation length are found, for both steady and fully oscillatory flows. It is shown that the maximum entrance length decreases with an increase in the oscillating frequency while the maximum recirculation length and recirculation area increase with an increase in oscillating frequency. The phase of a velocity signal is shown to be a strong function of its location. The phase difference between the velocities with respect to the different points along the centerline and those at the middle of the channel show a significant dependence on the driving frequency. There is a significant variation in the phase angles of the velocity signals computed between a point near the wall and that at the centerline. This phase difference decreases along the channel length and does not change beyond the entrance length. This feature can then be used to determine the maximum entrance length, which is otherwise problematic to ascertain in the case of fully oscillatory flows. The entrance length, thus obtained, is compared with that obtained from the velocity profile consideration and shows good similarity. The phase difference between pressure and velocity is also brought out in this work.

Asymptotic Expansion Homogenization for Multiscale Nuclear Fuel Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hales, J. D.; Tonks, M. R.; Chockalingam, K.

2015-03-01

Engineering scale nuclear fuel performance simulations can benefit by utilizing high-fidelity models running at a lower length scale. Lower length-scale models provide a detailed view of the material behavior that is used to determine the average material response at the macroscale. These lower length-scale calculations may provide insight into material behavior where experimental data is sparse or nonexistent. This multiscale approach is especially useful in the nuclear field, since irradiation experiments are difficult and expensive to conduct. The lower length-scale models complement the experiments by influencing the types of experiments required and by reducing the total number of experiments needed.more » This multiscale modeling approach is a central motivation in the development of the BISON-MARMOT fuel performance codes at Idaho National Laboratory. These codes seek to provide more accurate and predictive solutions for nuclear fuel behavior. One critical aspect of multiscale modeling is the ability to extract the relevant information from the lower length-scale sim- ulations. One approach, the asymptotic expansion homogenization (AEH) technique, has proven to be an effective method for determining homogenized material parameters. The AEH technique prescribes a system of equations to solve at the microscale that are used to compute homogenized material constants for use at the engineering scale. In this work, we employ AEH to explore the effect of evolving microstructural thermal conductivity and elastic constants on nuclear fuel performance. We show that the AEH approach fits cleanly into the BISON and MARMOT codes and provides a natural, multidimensional homogenization capability.« less

Heat Effects of Promoters and Determination of Burn Criterion in Promoted Combustion Testing

NASA Technical Reports Server (NTRS)

Sparks, Kyle M.; Stoltzfus, Joel M.; Steinberg, Theodore A.; Lynn, David

2010-01-01

Promoted ignition testing (NASA Test 17) [1] is used to determine the relative flammability of metal rods in oxygen-enriched atmospheres. A promoter is used to ignite a metal sample rod, initiating sample burning. If a predetermined length of the sample burns, beyond the promoter, the material is considered flammable at the condition tested. Historically, this burn length has been somewhat arbitrary. Experiments were performed to better understand this test by obtaining insight into the effect a burning promoter has on the preheating of a test sample. Test samples of several metallic materials were prepared and coupled to fast-responding thermocouples along their length. Thermocouple measurements and test video were synchronized to determine temperature increase with respect to time and length along each test sample. A recommended flammability burn length, based on a sample preheat of 500 F, was determined based on the preheated zone measured from these tests. This length was determined to be 30 mm (1.18 in.). Validation of this length and its rationale are presented.

A motion algorithm to extract physical and motion parameters of mobile targets from cone-beam computed tomographic images.

PubMed

Alsbou, Nesreen; Ahmad, Salahuddin; Ali, Imad

2016-05-17

A motion algorithm has been developed to extract length, CT number level and motion amplitude of a mobile target from cone-beam CT (CBCT) images. The algorithm uses three measurable parameters: Apparent length and blurred CT number distribution of a mobile target obtained from CBCT images to determine length, CT-number value of the stationary target, and motion amplitude. The predictions of this algorithm are tested with mobile targets having different well-known sizes that are made from tissue-equivalent gel which is inserted into a thorax phantom. The phantom moves sinusoidally in one-direction to simulate respiratory motion using eight amplitudes ranging 0-20 mm. Using this motion algorithm, three unknown parameters are extracted that include: Length of the target, CT number level, speed or motion amplitude for the mobile targets from CBCT images. The motion algorithm solves for the three unknown parameters using measured length, CT number level and gradient for a well-defined mobile target obtained from CBCT images. The motion model agrees with the measured lengths which are dependent on the target length and motion amplitude. The gradient of the CT number distribution of the mobile target is dependent on the stationary CT number level, the target length and motion amplitude. Motion frequency and phase do not affect the elongation and CT number distribution of the mobile target and could not be determined. A motion algorithm has been developed to extract three parameters that include length, CT number level and motion amplitude or speed of mobile targets directly from reconstructed CBCT images without prior knowledge of the stationary target parameters. This algorithm provides alternative to 4D-CBCT without requirement of motion tracking and sorting of the images into different breathing phases. The motion model developed here works well for tumors that have simple shapes, high contrast relative to surrounding tissues and move nearly in regular motion pattern that can be approximated with a simple sinusoidal function. This algorithm has potential applications in diagnostic CT imaging and radiotherapy in terms of motion management.

Actin kinetics shapes cortical network structure and mechanics

PubMed Central

Fritzsche, Marco; Erlenkämper, Christoph; Moeendarbary, Emad; Charras, Guillaume; Kruse, Karsten

2016-01-01

The actin cortex of animal cells is the main determinant of cellular mechanics. The continuous turnover of cortical actin filaments enables cells to quickly respond to stimuli. Recent work has shown that most of the cortical actin is generated by only two actin nucleators, the Arp2/3 complex and the formin Diaph1. However, our understanding of their interplay, their kinetics, and the length distribution of the filaments that they nucleate within living cells is poor. Such knowledge is necessary for a thorough comprehension of cellular processes and cell mechanics from basic polymer physics principles. We determined cortical assembly rates in living cells by using single-molecule fluorescence imaging in combination with stochastic simulations. We find that formin-nucleated filaments are, on average, 10 times longer than Arp2/3-nucleated filaments. Although formin-generated filaments represent less than 10% of all actin filaments, mechanical measurements indicate that they are important determinants of cortical elasticity. Tuning the activity of actin nucleators to alter filament length distribution may thus be a mechanism allowing cells to adjust their macroscopic mechanical properties to their physiological needs. PMID:27152338

Actin kinetics shapes cortical network structure and mechanics.

PubMed

Fritzsche, Marco; Erlenkämper, Christoph; Moeendarbary, Emad; Charras, Guillaume; Kruse, Karsten

2016-04-01

The actin cortex of animal cells is the main determinant of cellular mechanics. The continuous turnover of cortical actin filaments enables cells to quickly respond to stimuli. Recent work has shown that most of the cortical actin is generated by only two actin nucleators, the Arp2/3 complex and the formin Diaph1. However, our understanding of their interplay, their kinetics, and the length distribution of the filaments that they nucleate within living cells is poor. Such knowledge is necessary for a thorough comprehension of cellular processes and cell mechanics from basic polymer physics principles. We determined cortical assembly rates in living cells by using single-molecule fluorescence imaging in combination with stochastic simulations. We find that formin-nucleated filaments are, on average, 10 times longer than Arp2/3-nucleated filaments. Although formin-generated filaments represent less than 10% of all actin filaments, mechanical measurements indicate that they are important determinants of cortical elasticity. Tuning the activity of actin nucleators to alter filament length distribution may thus be a mechanism allowing cells to adjust their macroscopic mechanical properties to their physiological needs.

Effects of acidity on tree pollen germination and tube growth

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobson, J.S.; Van Rye, D.M.; Lassoie, J.P.

Several studies have indicated that pollen germination and tube growth are adversely affected by air pollutants. Pollutants may inhibit the function of pollen by reducing the number of pollen grains which germinate, by reducing the maximum length to which the pollen tubes grow, or by interfering with the formation of the generative cell. The paper reports on studies that are attempting to determine the effects acid rain may have on these crucial stages in the life histories of northeastern tree species. The first stage of this work assessed the effects of acidity in the growth medium on in vitro pollenmore » germination for four deciduous forest species common to central New York State, Betula lutea (yellow birch), B. lenta (black birch), Acer saccharum (sugar maple), and Cornus florida (flowering dogwood). Measurements were taken at the end of the growth period to determine the percentage of grains which had germinated, and to estimate the average tube length. To determine the effects of pollen on the growth medium, the pH of the germination drop was measured at the end of the growth period.« less

42 CFR 402.208 - Factors considered in determining whether to exclude, and the length of exclusion.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Factors considered in determining whether to..., ASSESSMENTS, AND EXCLUSIONS Exclusions § 402.208 Factors considered in determining whether to exclude, and the length of exclusion. (a) General factors. In determining whether to exclude a person and the length of...

Exploring the mechanisms of DNA hybridization on a surface

NASA Astrophysics Data System (ADS)

Schmitt, Terry J.; Rogers, J. Brandon; Knotts, Thomas A.

2013-01-01

DNA microarrays are a potentially disruptive technology in the medical field, but their use in such settings is limited by poor reliability. Microarrays work on the principle of hybridization and can only be as reliable as this process is robust, yet little is known at the molecular level about how the surface affects the hybridization process. This work uses advanced molecular simulation techniques and an experimentally parameterized coarse-grain model to determine the mechanism by which hybridization occurs on surfaces. The results show that hybridization proceeds through a mechanism where the untethered (target) strand often flips orientation. For evenly lengthed strands, the surface stabilizes hybridization (compared to the bulk system) by reducing the barriers involved in the flipping event. For unevenly lengthed strands, the surface destabilizes hybridization compared to the bulk, but the degree of destabilization is dependent on the location of the matching sequence. Taken as a whole, the results offer an unprecedented view into the hybridization process on surfaces and provide some insights as to the poor reproducibility exhibited by microarrays.

Stress analysis of mandibular implant overdenture with locator and bar/clip attachment: Comparative study with differences in the denture base length.

PubMed

Yoo, Jin Suk; Kwon, Kung-Rock; Noh, Kwantae; Lee, Hyeonjong; Paek, Janghyun

2017-06-01

The design of the attachment must provide an optimum stress distribution around the implant. In this study, for implant overdentures with a bar/clip attachment or a locator attachment, the stress transmitted to the implant in accordance with the change in the denture base length and the vertical pressure was measured and analyzed. Test model was created with epoxy resin. The strain gauges made a tight contact with implant surfaces. A universal testing machine was used to exert a vertical pressure on the mandibular implant overdenture and the strain rate of the implants was measured. Means and standard deviations of the maximum micro-deformation rates were determined. 1) Locator attachment: The implants on the working side generally showed higher strain than those on the non-working side. Tensile force was observed on the mesial surface of the implant on the working side, and the compressive force was applied to the buccal surface and on the surfaces of the implant on the non-working side. 2) Bar/clip attachment: The implants on the both non-working and working sides showed high strain; all surfaces except the mesial surface of the implant on the non-working side showed a compressive force. To minimize the strain on implants in mandibular implant overdentures, the attachment of the implant should be carefully selected and the denture base should be extended as much as possible.

Selection of Excavators for Earth Work on the Basis of their Performance

NASA Astrophysics Data System (ADS)

Vondráčková, Terezie; Voštová, Věra

2017-10-01

For the specific construction of the reconstruction of the railway section Ostrov nad Oslavou and Žďár nad Sázavou will be done removed the railway superstructure and the partial adjustment of the substructure including drainage. For the earthwork will be used excavators of the company Komatsu, with the possibility of adjustment of parameters of the working tool - the length of the bracket and the volume of the shovel. The determined value will be purely indicative, as it does not affect how the operator of the excavator handles the discharge of cargo means.

In Vivo Determination of the Complex Elastic Moduli of Cetacean Head Tissue

DTIC Science & Technology

2014-09-30

testing on Navy dolphins and stranded animals, for which permits and approvals have been obtained. 3 WORK COMPLETED System Design A prototype...chosen for the prototype system’s focal length. This would allow examination of brain tissue in a typical adult bottlenose dolphin , which is the...those observed in preliminary in vivo experiments (conducted under a separate effort) on two bottlenose dolphins and one beluga whale. System

Comparison of telomere length in black and white teachers from South Africa: the sympathetic activity and ambulatory blood pressure in Africans study.

PubMed

von Känel, Roland; Malan, Nico T; Hamer, Mark; Malan, Leoné

2015-01-01

Telomere length is a marker of biological aging that has been linked to cardiovascular disease risk. The black South African population is witnessing a tremendous increase in the prevalence of cardiovascular disease, part of which might be explained through urbanization. We compared telomere length between black South Africans and white South Africans and examined which biological and psychosocial variables played a role in ethnic difference in telomere length. We measured leukocyte telomere length in 161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease. Age, sex, years having lived in the area, human immunodeficiency virus (HIV) infection, hypertension, body mass index, dyslipidemia, hemoglobin A1c, C-reactive protein, smoking, physical activity, alcohol abuse, depressive symptoms, psychological distress, and work stress were considered as covariates. Black participants had shorter (median, interquartile range) relative telomere length (0.79, 0.70-0.95) than did white participants (1.06, 0.87-1.21; p < .001), and this difference changed very little after adjusting for covariates. In fully adjusted models, age (p < .001), male sex (p = .011), and HIV positive status (p = .023) were associated with shorter telomere length. Ethnicity did not significantly interact with any covariates in determining telomere length, including psychosocial characteristics. Black South Africans showed markedly shorter telomeres than did white South African counterparts. Age, male sex, and HIV status were associated with shorter telomere length. No interactions between ethnicity and biomedical or psychosocial factors were found. Ethnic difference in telomere length might primarily be explained by genetic factors.

Protein resistance efficacy of PEO-silane amphiphiles: Dependence on PEO-segment length and concentration

PubMed Central

Rufin, Marc A.; Barry, Mikayla E.; Adair, Paige A.; Hawkins, Melissa L.; Raymond, Jeffery E.; Grunlan, Melissa A.

2016-01-01

In contrast to modification with conventional PEO-silanes (i.e. no siloxane tether), silicones with dramatically enhanced protein resistance have been previously achieved via bulk-modification with poly (ethylene oxide) (PEO)-silane amphiphiles α-(EtO)3Si(CH2)2-oligodimethylsiloxane13-block-PEOn-OCH3 when n = 8 and 16 but not when n = 3. In this work, their efficacy was evaluated in terms of optimal PEO-segment length and minimum concentration required in silicone. For each PEO-silane amphiphile (n = 3, 8, and 16), five concentrations (5, 10, 25, 50, and 100 μmol per 1 g silicone) were evaluated. Efficacy was quantified in terms of the modified silicones’ abilities to undergo rapid, water-driven surface restructuring to form hydrophilic surfaces as well as resistance to fibrinogen adsorption. Only n = 8 and 16 were effective, with a lower minimum concentration in silicone required for n = 8 (10 μmol per 1 g silicone) versus n = 16 (25 μmol per 1 g silicone). Statement of Significance Silicone is commonly used for implantable medical devices, but its hydrophobic surface promotes protein adsorption which leads to thrombosis and infection. Typical methods to incorporate poly(ethylene oxide) (PEO) into silicones have not been effective due to the poor migration of PEO to the surface-biological interface. In this work, PEO-silane amphiphiles – comprised of a siloxane tether (m = 13) and variable PEO segment lengths (n = 3, 8, 16) – were blended into silicone to improve its protein resistance. The efficacy of the amphiphiles was determined to be dependent on PEO length. With the intermediate PEO length (n = 8), water-driven surface restructuring and resulting protein resistance was achieved with a concentration of only 1.7 wt%. PMID:27090588

23 CFR 658.16 - Exclusions from length and width determinations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... TRAFFIC OPERATIONS TRUCK SIZE AND WEIGHT, ROUTE DESIGNATIONS-LENGTH, WIDTH AND WEIGHT LIMITATIONS § 658.16 Exclusions from length and width determinations. (a) Vehicle components not excluded by law or regulation shall be included in the measurement of the length and width of commercial motor vehicles. (b) The...

Time off work in hand injury patients.

PubMed

Wong, Joyce Y P

2008-01-01

To evaluate the average time off work for patients with hand injuries as well as factors influencing the length of time off work for subjects who had returned to work. A total of 124 subjects were recruited and followed up 2 weeks after being discharged from therapy or until they resumed work. Factors affecting the time off work such as the severity of injury, number of operations, educational level, physical job demand, and presence of compensation claims, complications, and posttraumatic stress were also examined by multiple regression. The relationship between the severity of injury, time off work, and length of rehabilitation time was also examined. In 124 subjects, 109 resumed their previous jobs, with an average of 8 weeks off work and 9 weeks in regular rehabilitation. The result shows that the severity of injury, number of operations, and presence of compensation claims were the predictors for the length of time off work in hand injury patients. In addition, the time off work and length of rehabilitation time increased with more severe injury. However, a cross-over was noted in the severe grade of severity of injury; that is, the time off work was shorter than the length of rehabilitation time for those with a less severe level of injury (minor to moderate level) and vice versa for those with major severity of injury. To a certain extent, the result enhances our understanding of prolonged time off work after hand injury and may help to optimize rehabilitation after injury. For those who are in the high-risk group with factors that are not under control, early planning and retraining should be given to avoid prolonged time off work.

Monte-Carlo Simulation of 3H(γ, pn)n and 3He(γ, pp)n Experiments at HIγS★

NASA Astrophysics Data System (ADS)

Han, Z.; Friesen, F. Q. L.; Howell, C. R.; Ahmed, M. W.; Crowe, B. J.; Crowell, A. S.; Cumberbatch, L. C.; Fallin, B.; Ticehurst, D.; Tornow, W.; Witała, H.

2016-03-01

We are developing an experiment to measure the two and three-body (γ, p) differential cross sections (DCS) for 3H and 3He. These data will be used to determine the 1S0 nn scattering length (ann) and np scattering length (anp) respectively. This paper describes features of the Monte-Carlo (MC) simulation that will aid in the optimization of the experimental design and the data analysis approach. This work is supported in part by the U.S. Department of Energy under grant Nos. DE-FG02-97ER41033 and DE-SC0005367 and by the Polish National Science Center under Grant No.DEC-2013/10/M/ST2/00420.

Focus of a multilayer Laue lens with an aperture of 102 microns determined by ptychography at beamline 1-BM at the Advanced Photon Source

NASA Astrophysics Data System (ADS)

Macrander, Albert; Wojcik, Michael; Maser, Jörg; Bouet, Nathalie; Conley, Raymond

2017-09-01

Ptychography was used to determine the focus of a Multilayer-Laue-Lens (MLL) at beamline 1-BM at the Advanced Photon Source (APS). The MLL had a record aperture of 102 microns with 15170 layers. The measurements were made at 12 keV. The focal length was 9.6 mm, and the outer-most zone was 4 nm thick. MLLs with ever larger apertures are under continuous development since ever longer focal lengths, ever larger working distances, and ever increased flux in the focus are desired. A focus size of 25 nm was determined by ptychographic phase retrieval from a gold grating sample with 1 micron lines and spaces over 3.0 microns horizontal distance. The MLL was set to focus in the horizontal plane of the bending magnet beamline. A CCD with 13.0 micron pixel size positioned 1.13 m downstream of the sample was used to collect the transmitted intensity distribution. The beam incident on the MLL covered the whole 102 micron aperture in the horizontal focusing direction and 20 microns in the vertical direction. 160 iterations of the difference map algorithm were sufficient to obtain a reconstructed image of the sample. The present work highlights the utility of a bending magnet source at the APS for performing coherence-based experiments. Use of ptychography at 1-BM on MLL optics opens the way to study diffraction-limited imaging of other hard x-ray optics.

Determinants explaining the variability of hand-transmitted vibration emissions from two different work tasks: grinding and cutting using angle grinders.

PubMed

Liljelind, Ingrid; Pettersson, Hans; Nilsson, Leif; Wahlström, Jens; Toomingas, Allan; Lundström, Ronnie; Burström, Lage

2013-10-01

There are numerous factors including physical, biomechanical, and individual that influence exposure to hand-transmitted vibration (HTV) and cause variability in the exposure measurements. Knowledge of exposure variability and determinants of exposure could be used to improve working conditions. We performed a quasi-experimental study, where operators performed routine work tasks in order to obtain estimates of the variance components and to evaluate the effect of determinants, such as machine-wheel combinations and individual operator characteristics. Two pre-defined simulated work tasks were performed by 11 operators: removal of a weld puddle of mild steel and cutting of a square steel pipe. In both tasks, four angle grinders were used, two running on compressed air and two electrically driven. Two brands of both grinding and cutting wheels were used. Each operator performed both tasks twice in a random order with each grinder and wheel and the time to complete each task was recorded. Vibration emission values were collected and the wheel wear was measured as loss of weight. Operators' characteristics collected were as follows: age, body height and weight, length and volume of their hands, maximum hand grip force, and length of work experience with grinding machines (years). The tasks were also performed by one operator who used four machines of the same brand. Mixed and random effects models were used in the statistical evaluation. The statistical evaluation was performed for grinding and cutting separately and we used a measure referring to the sum of the 1-s r.m.s. average frequency-weighted acceleration over time for completing the work task (a(sa)). Within each work task, there was a significant effect as a result of the determinants 'the machine used', 'wheel wear', and 'time taken to complete the task'. For cutting, 'the brand of wheel' used also had a significant effect. More than 90% of the inherent variability in the data was explained by the determinants. The two electrically powered machines had a mean a(sa) that was 2.6 times higher than the two air-driven machines. For cutting, the effect of the brand of wheel on a(sa) was ~0.1 times. The a(sa) increased both with increasing wheel wear and with time taken to complete the work task. However, there were also a number of interaction effects which, to a minor extent, modified the a(sa). Only a minor part (1%) of the total variability was attributed to the operator: for cutting, the volume of the hands, maximum grip force, and body weight were significant, while for grinding, it was the maximum grip force. There was no clear difference in a(sa) between the four copies of the same brand of each machine. By including determinants that were attributed to the brand of both machine and wheel used as well as the time taken to complete the work task, we were able to explain >90% of the variability. The dominating determinant was the brand of the machine. Little variability was found between operators, indicating that the overall effect as due to the operator was small.

The Sensetivity of Flood Frequency Analysis on Record Length in Continuous United States

NASA Astrophysics Data System (ADS)

Hu, L.; Nikolopoulos, E. I.; Anagnostou, E. N.

2017-12-01

In flood frequency analysis (FFA), sufficiently long data series are important to get more reliable results. Compared to return periods of interest, at-site FFA usually needs large data sets. Generally, the precision of at site estimators and time-sampling errors are associated with the length of a gauged record. In this work, we quantify the difference with various record lengths. we use generalized extreme value (GEV) and Log Pearson type III (LP3), two traditional methods on annual maximum stream flows to undertake FFA, and propose quantitative ways, relative difference in median and interquartile range (IQR) to compare the flood frequency performances on different record length from selected 350 USGS gauges, which have more than 70 years record length in Continuous United States. Also, we group those gauges into different regions separately based on hydrological unit map and discuss the geometry impacts. The results indicate that long record length can avoid imposing an upper limit on the degree of sophistication. Working with relatively longer record length may lead accurate results than working with shorter record length. Furthermore, the influence of hydrologic unites for the watershed boundary dataset on those gauges also be presented. The California region is the most sensitive to record length, while gauges in the east perform steady.

30 CFR 1206.110 - How do I determine a transportation allowance under an arm's-length transportation contract?

Code of Federal Regulations, 2013 CFR

2013-07-01

... under an arm's-length transportation contract? 1206.110 Section 1206.110 Mineral Resources OFFICE OF... Oil § 1206.110 How do I determine a transportation allowance under an arm's-length transportation contract? (a) If you or your affiliate incur transportation costs under an arm's-length transportation...

30 CFR 1206.110 - How do I determine a transportation allowance under an arm's-length transportation contract?

Code of Federal Regulations, 2014 CFR

2014-07-01

... under an arm's-length transportation contract? 1206.110 Section 1206.110 Mineral Resources OFFICE OF... Oil § 1206.110 How do I determine a transportation allowance under an arm's-length transportation contract? (a) If you or your affiliate incur transportation costs under an arm's-length transportation...

30 CFR 1206.110 - How do I determine a transportation allowance under an arm's-length transportation contract?

Code of Federal Regulations, 2012 CFR

2012-07-01

... under an arm's-length transportation contract? 1206.110 Section 1206.110 Mineral Resources OFFICE OF... Oil § 1206.110 How do I determine a transportation allowance under an arm's-length transportation contract? (a) If you or your affiliate incur transportation costs under an arm's-length transportation...

30 CFR 206.110 - How do I determine a transportation allowance under an arm's-length transportation contract?

Code of Federal Regulations, 2010 CFR

2010-07-01

... under an arm's-length transportation contract? 206.110 Section 206.110 Mineral Resources MINERALS... § 206.110 How do I determine a transportation allowance under an arm's-length transportation contract? (a) If you or your affiliate incur transportation costs under an arm's-length transportation contract...

Ultrasonic Relaxation Study of 1-Alkyl-3-methylimidazolium-Based Room-Temperature Ionic Liquids: Probing the Role of Alkyl Chain Length in the Cation.

PubMed

Zorębski, Michał; Zorębski, Edward; Dzida, Marzena; Skowronek, Justyna; Jężak, Sylwia; Goodrich, Peter; Jacquemin, Johan

2016-04-14

Ultrasound absorption spectra of four 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imides were determined as a function of the alkyl chain length on the cation from 1-propyl to 1-hexyl from 293.15 to 323.15 K at ambient pressure. Herein, the ultrasound absorption measurements were carried out using a standard pulse technique within a frequency range from 10 to 300 MHz. Additionally, the speed of sound, density, and viscosity have been measured. The presence of strong dissipative processes during the ultrasound wave propagation was found experimentally, i.e., relaxation processes in the megahertz range were observed for all compounds over the whole temperature range. The relaxation spectra (both relaxation amplitude and relaxation frequency) were shown to be dependent on the alkyl side chain length of the 1-alkyl-3-methylimidazolium ring. In most cases, a single-Debye model described the absorption spectra very well. However, a comparison of the determined spectra with the spectra of a few other imidazolium-based ionic liquids reported in the literature (in part recalculated in this work) shows that the complexity of the spectra increases rapidly with the elongation of the alkyl chain length on the cation. This complexity indicates that both the volume viscosity and the shear viscosity are involved in relaxation processes even in relatively low frequency ranges. As a consequence, the sound velocity dispersion is present at relatively low megahertz frequencies.

Growth and physiological responses of some Capsicum frutescens varieties to copper stress

NASA Astrophysics Data System (ADS)

Jadid, Nurul; Maziyah, Rizka; Nurcahyani, Desy Dwi; Mubarokah, Nilna Rizqiyah

2017-06-01

Copper (Cu) is an essential micronutrient participating in various physiological processes. However, excessive uptake of this micronutrient could potentially affect plant growth and development as well as plant productivity. In this present work, growth and physiological responses of some Capsicum frustescens varieties to Cu stress were determined. Three C. frutescens varieties used in this work were var. Bara, CF 291, and Genie. In addition, these varieties were treated with different concentration of Cu (0, 30, 70, and 120 ppm). The growth and physiological responses measured in this work included plant height, root length, malondialdehyde (MDA), and chlorophyll. The result showed that all varieties tested relatively displayed plant growth reduction including plant height and root length. Likewise, an increase of MDA level, a major bioindicator for oxidative damage was also found in all varieties following exposure to elevated Cu concentration. Finally, the chlorophyll content was also affected indicated by a decreased amount of chlorophyll, especially in var. CF291. The overall results demonstrated that elevated Cu concentration might decrease C. frutescens productivity where among the three varieties tested, var CF 291 seemed to be the most sensitive varieties to Cu stress.

Job stress, unwinding and drinking in transit operators.

PubMed

Delaney, William P; Grube, Joel W; Greiner, Birgit; Fisher, June M; Ragland, David R

2002-07-01

This study tests the spillover model of the effects of work stress on after-work drinking, using the variable "length of time to unwind" as a mediator. A total of 1,974 transit operators were contacted and 1,553 (79%) of them participated in a personal interview. Complete data on the variables in this analysis were available for 1,208 respondents (84% men). Using latent variable structural equation modeling, a model was tested that predicted that daily job problems, skipped meals and less social support from supervisor would increase alcohol consumption through the mediator, length of time to unwind and relax after work. Increased alcohol consumption was, in turn, hypothesized to increase drinking problems. As predicted, skipped meals and daily job problems increased length of time to unwind and had an indirect positive relationship with overall drinking, even when controlling for drinking norms and demographic variables. Overall drinking was positively associated with drinking problems. Supervisor support at work, however, did not significantly influence length of time to unwind. Difficulty unwinding (longer time to unwind) did not have direct effects on drinking problems; however, indirect effects through overall drinking were observed. These results provide preliminary support for the mediating role of length of time to unwind and relax after work in a spillover model of the stress-drinking relationship. This research introduces a new mediator and empirical links between job problems, length of time to unwind, drinking and drinking problems, which ground more substantively the domains of work stress and alcohol consumption.

Determinants of Workplace Injuries and Violence Among Newly Licensed RNs.

PubMed

Unruh, Lynn; Asi, Yara

2018-06-01

Workplace injuries, such as musculoskeletal injuries, needlestick injuries, and emotional and physical violence, remain an issue in U.S. hospitals. To develop meaningful safety programs, it is important to identify workplace factors that contribute to injuries. This study explored factors that affect injuries in a sample of newly licensed registered nurses (NLRNs) in Florida. Regressions were run on models in which the dependent variable was the degree to which the respondent had experienced needlesticks, work-related musculoskeletal injuries, cuts or lacerations, contusions, verbal violence, physical violence, and other occupational injuries. A higher probability of these injuries was associated with greater length of employment, working evening or night shifts, working overtime, and reporting job difficulties and pressures. A lower probability was associated with working in a teaching hospital and working more hours. Study findings suggest that work environment issues must be addressed for safety programs to be effective.

Size and speed of the working stroke of cardiac myosin in situ

PubMed Central

Caremani, Marco; Pinzauti, Francesca; Reconditi, Massimo; Piazzesi, Gabriella; Stienen, Ger J. M.; Lombardi, Vincenzo; Linari, Marco

2016-01-01

The power in the myocardium sarcomere is generated by two bipolar arrays of the motor protein cardiac myosin II extending from the thick filament and pulling the thin, actin-containing filaments from the opposite sides of the sarcomere. Despite the interest in the definition of myosin-based cardiomyopathies, no study has yet been able to determine the mechanokinetic properties of this motor protein in situ. Sarcomere-level mechanics recorded by a striation follower is used in electrically stimulated intact ventricular trabeculae from the rat heart to determine the isotonic velocity transient following a stepwise reduction in force from the isometric peak force TP to a value T (0.8–0.2 TP). The size and the speed of the early rapid shortening (the isotonic working stroke) increase by reducing T from ∼3 nm per half-sarcomere (hs) and 1,000 s−1 at high load to ∼8 nm⋅hs−1 and 6,000 s−1 at low load. Increases in sarcomere length (1.9–2.2 μm) and external [Ca2+]o (1–2.5 mM), which produce an increase of TP, do not affect the dependence on T, normalized for TP, of the size and speed of the working stroke. Thus, length- and Ca2+-dependent increase of TP and power in the heart can solely be explained by modulation of the number of myosin motors, an emergent property of their array arrangement. The motor working stroke is similar to that of skeletal muscle myosin, whereas its speed is about three times slower. A new powerful tool for investigations and therapies of myosin-based cardiomyopathies is now within our reach. PMID:26984499

Effects of Circular DNA Length on Transfection Efficiency by Electroporation into HeLa Cells.

PubMed

Hornstein, Benjamin D; Roman, Dany; Arévalo-Soliz, Lirio M; Engevik, Melinda A; Zechiedrich, Lynn

2016-01-01

The ability to produce extremely small and circular supercoiled vectors has opened new territory for improving non-viral gene therapy vectors. In this work, we compared transfection of supercoiled DNA vectors ranging from 383 to 4,548 bp, each encoding shRNA against GFP under control of the H1 promoter. We assessed knockdown of GFP by electroporation into HeLa cells. All of our vectors entered cells in comparable numbers when electroporated with equal moles of DNA. Despite similar cell entry, we found length-dependent differences in how efficiently the vectors knocked down GFP. As vector length increased up to 1,869 bp, GFP knockdown efficiency per mole of transfected DNA increased. From 1,869 to 4,257 bp, GFP knockdown efficiency per mole was steady, then decreased with increasing vector length. In comparing GFP knockdown with equal masses of vectors, we found that the shorter vectors transfect more efficiently per nanogram of DNA transfected. Our results rule out cell entry and DNA mass as determining factors for gene knockdown efficiency via electroporation. The length-dependent effects we have uncovered are likely explained by differences in nuclear translocation or transcription. These data add an important step towards clinical applications of non-viral vector delivery.

Effects of Circular DNA Length on Transfection Efficiency by Electroporation into HeLa Cells

PubMed Central

Hornstein, Benjamin D.; Roman, Dany; Arévalo-Soliz, Lirio M.; Engevik, Melinda A.

2016-01-01

The ability to produce extremely small and circular supercoiled vectors has opened new territory for improving non-viral gene therapy vectors. In this work, we compared transfection of supercoiled DNA vectors ranging from 383 to 4,548 bp, each encoding shRNA against GFP under control of the H1 promoter. We assessed knockdown of GFP by electroporation into HeLa cells. All of our vectors entered cells in comparable numbers when electroporated with equal moles of DNA. Despite similar cell entry, we found length-dependent differences in how efficiently the vectors knocked down GFP. As vector length increased up to 1,869 bp, GFP knockdown efficiency per mole of transfected DNA increased. From 1,869 to 4,257 bp, GFP knockdown efficiency per mole was steady, then decreased with increasing vector length. In comparing GFP knockdown with equal masses of vectors, we found that the shorter vectors transfect more efficiently per nanogram of DNA transfected. Our results rule out cell entry and DNA mass as determining factors for gene knockdown efficiency via electroporation. The length-dependent effects we have uncovered are likely explained by differences in nuclear translocation or transcription. These data add an important step towards clinical applications of non-viral vector delivery. PMID:27918590

The Impact of 3-Option Responses to Multiple-Choice Questions on Guessing Strategies and Cut Score Determinations

PubMed Central

ROYAL, KENNETH D.; STOCKDALE, MYRAH R.

2017-01-01

Introduction: Research has asserted MCQ items using three response options (one correct answer with two distractors) is comparable to, and possibly preferable over, traditional MCQ item formats consisting of four response options (e.g., one correct answer with three distractors), or five response options (e.g., one correct answer with four distractors). Some medical educators have also adopted the practice of using 3-option responses on MCQ exams as a response to the difficulty experienced in generating additional plausible distractors. To date, however, little work has explored how 3-option responses might impact validity threats stemming from random guessing strategies, and what impact 3-option responses might have on cut-score determinations, particularly in the context of medical education classroom assessments. The purpose of this work is to further explore these critically important considerations that largely have gone ignored in the medical education literature to this point. Methods: A cumulative binomial distribution formula was used to calculate the probability that an examinee will answer at random a given number of items correctly on any exam (of any length). By way of a demonstration, a variety of scenarios were presented to illustrate how examination length and the number of response options impact examinees’ chances of passing a given examination, and how subsequent cut-score decisions may be impacted by these factors. Results: As a general rule, classroom assessments containing fewer items should utilize traditional 4-option or 5-option responses, whereas assessments of greater length are afforded greater flexibility in potentially utilizing 3-option responses. Conclusions: More research on items with 3-option responses is needed to better understand what value, if any, 3-option responses truly add to classroom assessments, and in what contexts potential benefits might be discernible. PMID:28367465

The Impact of 3-Option Responses to Multiple-Choice Questions on Guessing Strategies and Cut Score Determinations.

PubMed

Royal, Kenneth D; Stockdale, Myrah R

2017-04-01

Research has asserted MCQ items using three response options (one correct answer with two distractors) is comparable to, and possibly preferable over, traditional MCQ item formats consisting of four response options (e.g., one correct answer with three distractors), or five response options (e.g., one correct answer with four distractors). Some medical educators have also adopted the practice of using 3-option responses on MCQ exams as a response to the difficulty experienced in generating additional plausible distractors. To date, however, little work has explored how 3-option responses might impact validity threats stemming from random guessing strategies, and what impact 3-option responses might have on cut-score determinations, particularly in the context of medical education classroom assessments. The purpose of this work is to further explore these critically important considerations that largely have gone ignored in the medical education literature to this point. A cumulative binomial distribution formula was used to calculate the probability that an examinee will answer at random a given number of items correctly on any exam (of any length). By way of a demonstration, a variety of scenarios were presented to illustrate how examination length and the number of response options impact examinees' chances of passing a given examination, and how subsequent cut-score decisions may be impacted by these factors. As a general rule, classroom assessments containing fewer items should utilize traditional 4-option or 5-option responses, whereas assessments of greater length are afforded greater flexibility in potentially utilizing 3-option responses. More research on items with 3-option responses is needed to better understand what value, if any, 3-option responses truly add to classroom assessments, and in what contexts potential benefits might be discernible.

Multi-walled carbon nanotube length as a critical determinant of bioreactivity with primary human pulmonary alveolar cells

PubMed Central

Sweeney, Sinbad; Berhanu, Deborah; Misra, Superb K.; Thorley, Andrew J.; Valsami-Jones, Eugenia; Tetley, Teresa D.

2015-01-01

Multiwalled carbon nanotube (MWCNT) length is suggested to critically determine their pulmonary toxicity. This stems from in vitro and in vivo rodent studies and in vitro human studies using cell lines (typically cancerous). There is little data using primary human lung cells. We addressed this knowledge gap, using highly relevant, primary human alveolar cell models exposed to precisely synthesized and thoroughly characterized MWCNTs. In this work, transformed human alveolar type-I-like epithelial cells (TT1), primary human alveolar type-II epithelial cells (ATII) and alveolar macrophages (AM) were treated with increasing concentrations of MWCNTs before measuring cytotoxicity, inflammatory mediator release and MAP kinase signalling. Strikingly, we observed that short MWCNTs (~0.6 µm in length) induced significantly greater responses from the epithelial cells, whilst AM were particularly susceptible to long MWCNTs (~20 µm). These differences in the pattern of mediator release were associated with alternative profiles of JNK, p38 and ERK1/2 MAP kinase signal transduction within each cell type. This study, using highly relevant target human alveolar cells and well defined and characterized MWCNTs, shows marked cellular responses to the MWCNTs that vary according to the target cell type, as well as the aspect ratio of the MWCNT. PMID:25780270

30 CFR 1206.110 - How do I determine a transportation allowance under an arm's-length transportation contract?

Code of Federal Regulations, 2011 CFR

2011-07-01

... under an arm's-length transportation contract? 1206.110 Section 1206.110 Mineral Resources OFFICE OF... VALUATION Federal Oil § 1206.110 How do I determine a transportation allowance under an arm's-length transportation contract? (a) If you or your affiliate incur transportation costs under an arm's-length...

5 CFR 890.1017 - Determining length of debarment based on revocation or suspension of a provider's professional...

Code of Federal Regulations, 2010 CFR

2010-01-01

... Debarments § 890.1017 Determining length of debarment based on revocation or suspension of a provider's... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Determining length of debarment based on revocation or suspension of a provider's professional licensure. 890.1017 Section 890.1017 Administrative...

Diffusion length measurements of thin GaAs solar cells by means of energetic electrons

NASA Technical Reports Server (NTRS)

Vonross, O.

1980-01-01

A calculation of the short circuit current density (j sub sc) of a thin GaAs solar cell induced by fast electrons is presented. It is shown that in spite of the disparity in thickness between the N-type portion of the junction and the P-type portion of the junction, the measurement of the bulk diffusion length L sub p of the N-type part of the junction is seriously hampered due to the presence of a sizable contribution to the j sub sc from the P-type region of the junction. Corrections of up to 50% had to be made in order to interpret the data correctly. Since these corrections were not amenable to direct measurements it is concluded that the electron beam method for the determination of the bulk minority carrier diffusion length, which works so well for Si solar cells, is a poor method when applied to thin GaAs cells.

Effect of Structural Parameters on the Combustion Performance of Platelet Engines

NASA Astrophysics Data System (ADS)

Liang, Yin; Liu, Weiqiang

2017-12-01

Numerical simulation was adopted to determine its flow and combustion characteristics by using gaseous methane and oxygen as the main propellants, the effects of nozzle space and expanding angle are examined for the single element splash platelet injector. Navier-Stokes (N-S) equations were solved for the gas-gas flow field with a reduced mechanism involving 9 species and 1 reaction. Results indicated that large corner recirculation zones are produced in the combustor head. This phenomenon consequently enhances mixing and stabilizes combustion, but non-uniformity in temperature contour is observed in the combustor head. Recirculation zone decreases as nozzle space increases, which induces the decrease of maximum temperature and high temperature regions, but it has little influence on the combustion efficiency and combustion length. The combustion length and maximum temperature decrease initially and then increase as expanding angle increases. Conversely, a D value of 2.4 mm and γ value of 60° are selected for the future works because of the shortest combustion length and minimum temperature of the injector faceplate.

Parenting, corpus callosum, and executive function in preschool children.

PubMed

Kok, Rianne; Lucassen, Nicole; Bakermans-Kranenburg, Marian J; van IJzendoorn, Marinus H; Ghassabian, Akhgar; Roza, Sabine J; Govaert, Paul; Jaddoe, Vincent W; Hofman, Albert; Verhulst, Frank C; Tiemeier, Henning

2014-01-01

In this longitudinal population-based study (N = 544), we investigated whether early parenting and corpus callosum length predict child executive function abilities at 4 years of age. The length of the corpus callosum in infancy was measured using postnatal cranial ultrasounds at 6 weeks of age. At 3 years, two aspects of parenting were observed: maternal sensitivity during a teaching task and maternal discipline style during a discipline task. Parents rated executive function problems at 4 years of age in five domains of inhibition, shifting, emotional control, working memory, and planning/organizing, using the Behavior Rating Inventory of Executive Function-Preschool Version. Maternal sensitivity predicted less executive function problems at preschool age. A significant interaction was found between corpus callosum length in infancy and maternal use of positive discipline to determine child inhibition problems: The association between a relatively shorter corpus callosum in infancy and child inhibition problems was reduced in children who experienced more positive discipline. Our results point to the buffering potential of positive parenting for children with biological vulnerability.

Computational knee ligament modeling using experimentally determined zero-load lengths.

PubMed

Bloemker, Katherine H; Guess, Trent M; Maletsky, Lorin; Dodd, Kevin

2012-01-01

This study presents a subject-specific method of determining the zero-load lengths of the cruciate and collateral ligaments in computational knee modeling. Three cadaver knees were tested in a dynamic knee simulator. The cadaver knees also underwent manual envelope of motion testing to find their passive range of motion in order to determine the zero-load lengths for each ligament bundle. Computational multibody knee models were created for each knee and model kinematics were compared to experimental kinematics for a simulated walk cycle. One-dimensional non-linear spring damper elements were used to represent cruciate and collateral ligament bundles in the knee models. This study found that knee kinematics were highly sensitive to altering of the zero-load length. The results also suggest optimal methods for defining each of the ligament bundle zero-load lengths, regardless of the subject. These results verify the importance of the zero-load length when modeling the knee joint and verify that manual envelope of motion measurements can be used to determine the passive range of motion of the knee joint. It is also believed that the method described here for determining zero-load length can be used for in vitro or in vivo subject-specific computational models.

Determination of Pass/Fail Criteria for Promoted Combustion Testing

NASA Technical Reports Server (NTRS)

Sparks, Kyle M.; Stoltzfus, Joel M.; Steinberg, Theodore A.; Lynn, David

2009-01-01

Promoted ignition testing is used to determine the relative flammability of metal rods in oxygen-enriched atmospheres. In these tests, a promoter is used to ignite each metal rod to start the sample burning. Experiments were performed to better understand the promoted ignition test by obtaining insight into the effect a burning promoter has on the preheating of a test sample. Test samples of several metallic materials were prepared and coupled to fast-responding thermocouples along their length. Various ignition promoters were used to ignite the test samples. The thermocouple measurements and test video was synchronized to determine temperature increase with respect to time and length along each test sample. A recommended length of test sample that must be consumed to be considered a flammable material was determined based on the preheated zone measured from these tests. This length was determined to be 30 mm (1.18 in.). Validation of this length and its rationale are presented.

Lagrangian formulation for penny-shaped and Perkins-Kern geometry models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, W.S.

1989-09-01

This paper discusses basic theories for vertical penny-shaped and Perkins-Kern (PK) geometry models developed with a Lagrangian formulation combined with a virtual-work analysis. The Lagrangian formulation yields a pair of nonlinear equations in R/sub f/ or L/sub f/ and b/sub f/, the fracture radius or length and half-width. By introduction of a virtual-work analysis, a simple equation is obtained that can be solved numerically. This equation is written in a form that can be used to determine fracture geometry when the fluid-loss coefficient of the fracturing fluid is known. Also, this equation, coupled with a material-balance equation after shut-in, canmore » be used to analyze pressure-decline data after shut-in to determine the effective fluid-loss coefficient and fracture geometry.« less

Strongly extended diffusion length for the nonequilibrium magnons in Y 3 F e 5 O 12 by photoexcitation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, S. H.; Li, G.; Guo, E. J.

Y 3Fe 5O 12 (YIG) is known for its long magnon diffusion length. Although it has the known lowest damping rate, an even longer diffusion distance is still highly desired since it may lead to a much more efficient information transmission and processing. While most of previous works focused on the generation and detection of magnons in YIG, here we demonstrate how to depress the damping rate during the diffusion of magnon. By selectively exciting the spin state transition of the Fe ions in YIG, we successfully increase magnon diffusion length by one order of magnitude, i.e., from the previousmore » reported ~10 μm up to ~156 μm (for the sample prepared by liquid phase epitaxy) and ~180 μm (for the sample prepared by pulsed laser deposition) at room temperature. The diffusion length, determined by nonlocal geometry, is ~30 μm for the magnons induced by visible light and above 150 μm for the laser of 980 nm. In addition to thermal gradient, light excitation affects the electron configuration of the Fe 3+ ion in YIG. Long-wavelength laser is more effective since it causes a transition of the Fe 3+ ions in FeO 6 octahedron from a high spin to a low spin state and thus causes a magnon softening which favors a long-distance diffusion. Furthermore, the present work paves the way toward an efficient tuning of magnon transport which is crucially important for magnon spintronics.« less

Strongly extended diffusion length for the nonequilibrium magnons in Y 3 F e 5 O 12 by photoexcitation

DOE PAGES

Wang, S. H.; Li, G.; Guo, E. J.; ...

2018-05-09

Y 3Fe 5O 12 (YIG) is known for its long magnon diffusion length. Although it has the known lowest damping rate, an even longer diffusion distance is still highly desired since it may lead to a much more efficient information transmission and processing. While most of previous works focused on the generation and detection of magnons in YIG, here we demonstrate how to depress the damping rate during the diffusion of magnon. By selectively exciting the spin state transition of the Fe ions in YIG, we successfully increase magnon diffusion length by one order of magnitude, i.e., from the previousmore » reported ~10 μm up to ~156 μm (for the sample prepared by liquid phase epitaxy) and ~180 μm (for the sample prepared by pulsed laser deposition) at room temperature. The diffusion length, determined by nonlocal geometry, is ~30 μm for the magnons induced by visible light and above 150 μm for the laser of 980 nm. In addition to thermal gradient, light excitation affects the electron configuration of the Fe 3+ ion in YIG. Long-wavelength laser is more effective since it causes a transition of the Fe 3+ ions in FeO 6 octahedron from a high spin to a low spin state and thus causes a magnon softening which favors a long-distance diffusion. Furthermore, the present work paves the way toward an efficient tuning of magnon transport which is crucially important for magnon spintronics.« less

Strongly extended diffusion length for the nonequilibrium magnons in Y3F e5O12 by photoexcitation

NASA Astrophysics Data System (ADS)

Wang, S. H.; Li, G.; Guo, E. J.; Zhao, Y.; Wang, J. Y.; Zou, L. K.; Yan, H.; Cai, J. W.; Zhang, Z. T.; Wang, M.; Tian, Y. Y.; Zheng, X. L.; Sun, J. R.; Jin, K. X.

2018-05-01

Y3F e5O12 (YIG) is known for its long magnon diffusion length. Although it has the known lowest damping rate, an even longer diffusion distance is still highly desired since it may lead to a much more efficient information transmission and processing. While most of previous works focused on the generation and detection of magnons in YIG, here we demonstrate how to depress the damping rate during the diffusion of magnon. By selectively exciting the spin state transition of the Fe ions in YIG, we successfully increase magnon diffusion length by one order of magnitude, i.e., from the previous reported ˜10 μm up to ˜156 μm (for the sample prepared by liquid phase epitaxy) and ˜180 μm (for the sample prepared by pulsed laser deposition) at room temperature. The diffusion length, determined by nonlocal geometry, is ˜30 μm for the magnons induced by visible light and above 150 μm for the laser of 980 nm. In addition to thermal gradient, light excitation affects the electron configuration of the F e3 + ion in YIG. Long-wavelength laser is more effective since it causes a transition of the F e3 + ions in Fe O6 octahedron from a high spin to a low spin state and thus causes a magnon softening which favors a long-distance diffusion. The present work paves the way toward an efficient tuning of magnon transport which is crucially important for magnon spintronics.

Employment and work schedule are related to telomere length in women

PubMed Central

Parks, C G; DeRoo, L A; Miller, D B; McCanlies, E C; Cawthon, R M; Sandler, D P

2011-01-01

Objectives To examine the association of employment and work schedule with shorter DNA telomeres, a marker of cellular ageing and disease risk factor, and consider whether differences were related to health, behaviours and sociodemographic factors, or varied by stress levels or menopausal status. Methods This cross-sectional analysis of 608 women aged 35–74 in the Sister Study examined determinants of relative telomere length (rTL) measured by quantitative PCR in leucocyte DNA. Age-adjusted regression models estimated base pair (bp) rTL differences for current and lifetime schedule characteristics (ie, part-time, full-time or overtime hours; multiple jobs; irregular hours; shiftwork; work at night). Covariates included race, smoking, perceived stress, sleep, physical activity, health and menopausal status, education, marital status, live births, children under 18, measured body mass index and urinary stress hormones. Results Compared with non-employed women with moderate or substantial past work histories (n=190), those currently working full-time (n=247; median 40 h/week) had a shorter rTL, an age-adjusted difference of −329 bp (95% CI −110 to −548). Longer-duration full-time work was also associated with shorter rTL (age-adjusted difference of −472 bp, 95% CI −786 to −158 for 20+ vs 1–5 years). Findings were not explained by health and demographic covariates. However, rTL differences for working at least full-time were greater in women with higher stress and epinephrine levels. Conclusions Current and long-term full-time work were associated with shorter rTL, with differences of similar magnitude to smoking and history of heart disease or diabetes. Longitudinal data with specific stress measures are needed to further evaluate the impact of work schedule on rTL. PMID:21540175

Employment and work schedule are related to telomere length in women.

PubMed

Parks, C G; DeRoo, L A; Miller, D B; McCanlies, E C; Cawthon, R M; Sandler, D P

2011-08-01

To examine the association of employment and work schedule with shorter DNA telomeres, a marker of cellular ageing and disease risk factor, and consider whether differences were related to health, behaviours and sociodemographic factors, or varied by stress levels or menopausal status. This cross-sectional analysis of 608 women aged 35-74 in the Sister Study examined determinants of relative telomere length (rTL) measured by quantitative PCR in leucocyte DNA. Age-adjusted regression models estimated base pair (bp) rTL differences for current and lifetime schedule characteristics (ie, part-time, full-time or overtime hours; multiple jobs; irregular hours; shiftwork; work at night). Covariates included race, smoking, perceived stress, sleep, physical activity, health and menopausal status, education, marital status, live births, children under 18, measured body mass index and urinary stress hormones. Compared with non-employed women with moderate or substantial past work histories (n=190), those currently working full-time (n=247; median 40 h/week) had a shorter rTL, an age-adjusted difference of -329 bp (95% CI -110 to -548). Longer-duration full-time work was also associated with shorter rTL (age-adjusted difference of -472 bp, 95% CI -786 to -158 for 20+ vs 1-5 years). Findings were not explained by health and demographic covariates. However, rTL differences for working at least full-time were greater in women with higher stress and epinephrine levels. Current and long-term full-time work were associated with shorter rTL, with differences of similar magnitude to smoking and history of heart disease or diabetes. Longitudinal data with specific stress measures are needed to further evaluate the impact of work schedule on rTL.

Fall risk assessment: retrospective analysis of Morse Fall Scale scores in Portuguese hospitalized adult patients.

PubMed

Sardo, Pedro Miguel Garcez; Simões, Cláudia Sofia Oliveira; Alvarelhão, José Joaquim Marques; Simões, João Filipe Fernandes Lindo; Melo, Elsa Maria de Oliveira Pinheiro de

2016-08-01

The Morse Fall Scale is used in several care settings for fall risk assessment and supports the implementation of preventive nursing interventions. Our work aims to analyze the Morse Fall Scale scores of Portuguese hospitalized adult patients in association with their characteristics, diagnoses and length of stay. Retrospective cohort analysis of Morse Fall Scale scores of 8356 patients hospitalized during 2012. Data were associated to age, gender, type of admission, specialty units, length of stay, patient discharge, and ICD-9 diagnosis. Elderly patients, female, with emergency service admission, at medical units and/or with longer length of stays were more frequently included in the risk group for falls. ICD-9 diagnosis may also be an important risk factor. More than a half of hospitalized patients had "medium" to "high" risk of falling during the length of stay, which determines the implementation and maintenance of protocoled preventive nursing interventions throughout hospitalization. There are several fall risk factors not assessed by Morse Fall Scale. There were no statistical differences in Morse Fall Scale score between the first and the last assessment. Copyright © 2015 Elsevier Inc. All rights reserved.

Cyclic fatigue of ProTaper instruments.

PubMed

Lopes, Hélio Pereira; Moreira, Edson Jorge Lima; Elias, Carlos Nelson; de Almeida, Renata Andriola; Neves, Mônica Schultz

2007-01-01

The present work evaluated the influence of the curved segment length of artificial root canals (the arc) and the number of cycles necessary to fracture engine-driven nickel-titanium endodontic instruments. ProTaper F3 25-mm files at 250 rpm were used in two artificial canals. The artificial canals were made of stainless steel with an inner diameter of 1.04 mm, a total length of 20 mm, and arc on the ends with a radius of curvature of 6 mm. The arc length of the first tube measured 9.4 mm, and the straight part measured 10.6 mm. The second tube was 14.1 mm long, and the straight part measured 5.9 mm. We determined the fracture surface distances and the number of cycles necessary to induce fatigue fracture in the ProTaper F3 instruments. The fracture surfaces and the helical shaft of the instruments were investigated using a scanning electron microscope. The results indicated that the required number of cycles to cause a fracture was influenced by the canal arc length, the morphology of the fractured surface presented ductile characteristics, and plastic deformation in the helical shaft of the fractured instruments did not occur.

The proportion of the face in younger adults using the thumb rule of Leonardo da Vinci.

PubMed

Oguz, O

1996-01-01

The present study was conducted to examine whether the thumb rule of Leonardo da Vinci could be an objective method in the determination of the natural and artistic proportions of human face. In this study, a sample of 400 subjects (200 male and 200 female, 22-25 years old) was used. Measurements were made of the length of thumb, the length of ear, the approximate distances between the hair line and the glabella or eyebrows, between the glabella or eyebrows and the tip of the nose and the distance between the nose and the chin, and the distance between the ear and the lateral aspect of the eye. The results obtained in the males and females showed significant (p < 0.01) correlations between the length of thumb and the proportions of the face examined in the study. Additionally, the height of the face was found to be almost three times the length of the thumb. However, the measurements obtained from female subjects were on average smaller than those taken from males. The results obtained in this experiment could be of value in understanding of the evaluation of the face for the people working in plastic surgery or art.

Meta-analysis of the effect of road work zones on crash occurrence.

PubMed

Theofilatos, Athanasios; Ziakopoulos, Apostolos; Papadimitriou, Eleonora; Yannis, George; Diamandouros, Konstantinos

2017-11-01

There is strong evidence that work zones pose increased risk of crashes and injuries. The two most common risk factors associated with increased crash frequencies are work zone duration and length. However, relevant research on the topic is relatively limited. For that reason, this paper presents formal meta-analyses of studies that have estimated the relationship between the number of crashes and work zone duration and length, in order to provide overall estimates of those effects on crash frequencies. All studies presented in this paper are crash prediction models with similar specifications. According to the meta-analyses and after correcting for publication bias when it was considered appropriate, the summary estimates of regression coefficients were found to be 0.1703 for duration and 0.862 for length. These effects were significant for length but not for duration. However, the overall estimate of duration was significant before correcting for publication bias. Separate meta-analyses on the studies examining both duration and length was also carried out in order to have rough estimates of the combined effects. The estimate of duration was found to be 0.953, while for length was 0.847. Similar to previous meta-analyses the effect of duration after correcting for publication bias is not significant, while the effect of length was significant at a 95% level. Meta-regression findings indicate that the main factors influencing the overall estimates of the beta coefficients are study year and region for duration and study year and model specification for length. Copyright © 2017 Elsevier Ltd. All rights reserved.

Driver responses to differing urban work zone configurations.

PubMed

Morgan, J F; Duley, A R; Hancock, P A

2010-05-01

This study reports the results of a simulator-based assessment of driver response to two different urban highway work zone configurations. One configuration represented an existing design which was contrasted with a second configuration that presented a reduced taper length prototype work zone design. Twenty-one drivers navigated the two different work zones in two different conditions, one with and one without a lead vehicle; in this case a bus. Measures of driver speed, braking, travel path, and collision frequency were recorded. Drivers navigated significantly closer to the boundary of the work area in the reduced taper length design. This proximity effect was moderated by the significant interaction between lead vehicle and taper length and such interactive effects were also observed for driver speed at the end of the work zone and the number of collisions observed within the work zone itself. These results suggest that reduced taper length poses an increase in risk to both drivers and work zone personnel, primarily when driver anticipation is reduced by foreshortened viewing distances. Increase in such risk is to a degree offset by the reduction of overall exposure to the work zone that a foreshortened taper creates. The benefits and limitations to a simulation-based approach to the assessment and prediction of driver behavior in different work zone configurations are also discussed. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

Combination of Eight Alleles at Four Quantitative Trait Loci Determines Grain Length in Rice

PubMed Central

Zeng, Yuxiang; Ji, Zhijuan; Wen, Zhihua; Liang, Yan; Yang, Changdeng

2016-01-01

Grain length is an important quantitative trait in rice (Oryza sativa L.) that influences both grain yield and exterior quality. Although many quantitative trait loci (QTLs) for grain length have been identified, it is still unclear how different alleles from different QTLs regulate grain length coordinately. To explore the mechanisms of QTL combination in the determination of grain length, five mapping populations, including two F2 populations, an F3 population, an F7 recombinant inbred line (RIL) population, and an F8 RIL population, were developed from the cross between the U.S. tropical japonica variety ‘Lemont’ and the Chinese indica variety ‘Yangdao 4’ and grown under different environmental conditions. Four QTLs (qGL-3-1, qGL-3-2, qGL-4, and qGL-7) for grain length were detected using both composite interval mapping and multiple interval mapping methods in the mapping populations. In each locus, there was an allele from one parent that increased grain length and another allele from another parent that decreased it. The eight alleles in the four QTLs were analyzed to determine whether these alleles act additively across loci, and lead to a linear relationship between the predicted breeding value of QTLs and phenotype. Linear regression analysis suggested that the combination of eight alleles determined grain length. Plants carrying more grain length-increasing alleles had longer grain length than those carrying more grain length-decreasing alleles. This trend was consistent in all five mapping populations and demonstrated the regulation of grain length by the four QTLs. Thus, these QTLs are ideal resources for modifying grain length in rice. PMID:26942914

[PSYCHO PHYSIOLOGICAL MARKERS OF ACCELERATED AGING AMONG THOSE WORKING WITH OCCUPATIONAL HAZARDS].

PubMed

Bashkireva, A S; Kachan, Ye Yu; Kulapina, M E

2015-01-01

We assessed the significance of psycho physiological markers of accelerated aging of the function of attention using comparative analysis of two occupational groups in order to reveal how the working process affects mental work capacity. We revealed peculiarities of systemic structure of functions which determine mental work capacity depending on the age and length of service in lorry drivers. It was proved that decrease in the mnestic functions of lorry-drivers takes place 10-15 years earlier compared to the control group. Psycho physiological indices, reflecting the functioning of attention, decreased not only with aging but also with longer driving experience. Our results show that it is necessary to conduct further studies of psycho physiological markers of age-related decrease in short-term memory depending on the activities at work in order to prevent accelerated aging and achieve professional longevity.

SU-D-213-03: Towards An Optimized 3D Scintillation Dosimetry Tool for Quality Assurance of Dynamic Radiotherapy Techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rilling, M; Centre de Recherche sur le Cancer, Hôtel-Dieu de Québec, Quebec City, QC; Département de radio-oncologie, CHU de Québec, Quebec City, QC

2015-06-15

Purpose: The purpose of this work is to simulate a multi-focus plenoptic camera used as the measuring device in a real-time three-dimensional scintillation dosimeter. Simulating and optimizing this realistic optical system will bridge the technological gap between concept validation and a clinically viable tool that can provide highly efficient, accurate and precise measurements for dynamic radiotherapy techniques. Methods: The experimental prototype, previously developed for proof of concept purposes, uses an off-the-shelf multi-focus plenoptic camera. With an array of interleaved microlenses of different focal lengths, this camera records spatial and angular information of light emitted by a plastic scintillator volume. Themore » three distinct microlens focal lengths were determined experimentally for use as baseline parameters by measuring image-to-object magnification for different distances in object space. A simulated plenoptic system was implemented using the non-sequential ray tracing software Zemax: this tool allows complete simulation of multiple optical paths by modeling interactions at interfaces such as scatter, diffraction, reflection and refraction. The active sensor was modeled based on the camera manufacturer specifications by a 2048×2048, 5 µm-pixel pitch sensor. Planar light sources, simulating the plastic scintillator volume, were employed for ray tracing simulations. Results: The microlens focal lengths were determined to be 384, 327 and 290 µm. A realistic multi-focus plenoptic system, with independently defined and optimizable specifications, was fully simulated. A f/2.9 and 54 mm-focal length Double Gauss objective was modeled as the system’s main lens. A three-focal length hexagonal microlens array of 250-µm thickness was designed, acting as an image-relay system between the main lens and sensor. Conclusion: Simulation of a fully modeled multi-focus plenoptic camera enables the decoupled optimization of the main lens and microlens specifications. This work leads the way to improving the 3D dosimeter’s achievable resolution, efficiency and build for providing a quality assurance tool fully meeting clinical needs. M.R. is financially supported by a Master’s Canada Graduate Scholarship from the NSERC. This research is also supported by the NSERC Industrial Research Chair in Optical Design.« less

Measuring and improving productivity in general radiology.

PubMed

Wilt, Michelle A; Miranda, Rafael; Johnson, C Daniel; Love, Peggy Sue

2010-10-01

The aim of this study was to determine a method of measuring productivity among general radiographers in a moderate-sized hospital and to improve and sustain productivity within that work area. The average times needed to perform the 13 most common examinations were measured. Performance of the various examinations was tracked and multiplied by the time allocated per procedure; this measure was divided by the length of the work shift to determine productivity. Productivity measures were shared among the work group, and decisions to improve productivity (eg, whether to fill open positions) were made by group members. Average time spent per examination type was calculated (range, 10 minutes to 1 hour 16 minutes). At baseline (February 2008), group productivity was 50%. Productivity increased during the first year of monitoring and was sustained through November 2009 (productivity range, 57%-63%). Yearly savings from not filling open positions were estimated to be $174,000. Productivity in a general radiology work area can be measured. Consensus among the work group helped increase productivity and assess progress. This methodology, if widely adopted, could be standardized and used to compare productivity across departments and institutions. Copyright © 2010 American College of Radiology. Published by Elsevier Inc. All rights reserved.

[PSYCHO PHYSIOLOGICAL MARKERS OF ACCELERATED AGING AMONG THOSE WORKING WITH OCCUPATIONAL HAZARDS].

PubMed

Bashkireva, A S; Kachan, Ye Yu; Kulapina, M E

2015-01-01

Using comparative analysis of two occupational groups we assessed the significance of psycho physiological markers of short-term memory accelerated aging in order to reveal how the age-related changes and working process affect mental work capacity. We revealed peculiarities of systemic structure of functions which determine mental work capacity depending on the age and length of service in lorry drivers. It was proved that age and long driving experience affect mnestic functions which show up quantitative and qualitative changes such as reduced volume of memorized information, longer time needed to memorize it, and tendency to diminished accuracy of memorization. We also proved that premature age-related changes of psycho physiological indices in drivers are the "risk indicators", while long driving experience is a real risk factor contributing to the acceleration of aging.

Computational Knee Ligament Modeling Using Experimentally Determined Zero-Load Lengths

PubMed Central

Bloemker, Katherine H; Guess, Trent M; Maletsky, Lorin; Dodd, Kevin

2012-01-01

This study presents a subject-specific method of determining the zero-load lengths of the cruciate and collateral ligaments in computational knee modeling. Three cadaver knees were tested in a dynamic knee simulator. The cadaver knees also underwent manual envelope of motion testing to find their passive range of motion in order to determine the zero-load lengths for each ligament bundle. Computational multibody knee models were created for each knee and model kinematics were compared to experimental kinematics for a simulated walk cycle. One-dimensional non-linear spring damper elements were used to represent cruciate and collateral ligament bundles in the knee models. This study found that knee kinematics were highly sensitive to altering of the zero-load length. The results also suggest optimal methods for defining each of the ligament bundle zero-load lengths, regardless of the subject. These results verify the importance of the zero-load length when modeling the knee joint and verify that manual envelope of motion measurements can be used to determine the passive range of motion of the knee joint. It is also believed that the method described here for determining zero-load length can be used for in vitro or in vivo subject-specific computational models. PMID:22523522

Bandwidth and Detection of Packet Length Covert Channels

DTIC Science & Technology

2011-03-01

Shared Resource Matrix ( SRM ): Develop a matrix of all resources on one side and on the other all the processes. Then, determine which process uses which...system calls. This method is similar to that of the SRM . Covert channels have also been created by modulating packet timing, data and headers of net- work...analysis, noninterference analysis, SRM method, and the covert flow tree method [4]. These methods can be used during the design phase of a system. Less

Structural Studies on Cytosolic Domain of Magnesium Transporter MgtE from Enterococcus faecalis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ragumani, S.; Sauder, J; Burley, S

2009-01-01

Magnesium (Mg{sup 2+}) is an essential element for growth and maintenance of living cells. It acts as a cofactor for many enzymes and is also essential for stability of the plasma membrane. There are two distinct classes of magnesium transporters identified in bacteria that convey Mg{sup 2+} from periplasm to cytoplasm [ATPase-dependent (MgtA and MgtB) and constitutively active (CorA and MgtE)]. Previously published work on Mg{sup 2+} transporters yielded structures of full length MgtE from Thermus thermophilus, determined at 3.5 {angstrom} resolution, and its cytoplasmic domain with and without bond Mg{sup 2+} determined at 2.3 and 3.9 {angstrom} resolution, respectively.more » Here, they report the crystal structure of the Mg{sup 2+} bound form of the cytosolic portion of MgtE (residues 6-262) from Enterococcus faecalis at 2.2 {angstrom} resolution. The present structure and magnesium bound cytosolic domain structure from T. thermophilus (PDB ID: 2YVY) are structurally similar. Three magnesium binding sites are common to both MgtE full length and the present structure. Their work revealed an additional Mg{sup 2+} binding site in the E. faecalis structure. In this report, they discuss the functional significance of Mg{sup 2+} binding sites in the cytosolic domains of MgtE transporters.« less

Pelvic step: the contribution of horizontal pelvis rotation to step length in young healthy adults walking on a treadmill.

PubMed

Liang, Bo Wei; Wu, Wen Hua; Meijer, Onno G; Lin, Jian Hua; Lv, Go Rong; Lin, Xiao Cong; Prins, Maarten R; Hu, Hai; van Dieën, Jaap H; Bruijn, Sjoerd M

2014-01-01

Transverse plane pelvis rotations during walking may be regarded as the "first determinant of gait". This would assume that pelvis rotations increase step length, and thereby reduce the vertical movements of the centre of mass-"the pelvic step". We analysed the pelvic step using 20 healthy young male subjects, walking on a treadmill at 1-5 km/h, with normal or big steps. Step length, pelvis rotation amplitude, leg-pelvis relative phase, and the contribution of pelvis rotation to step length were calculated. When speed increased in normal walking, pelvis rotation changed from more out-of-phase to in-phase with the upper leg. Consequently, the contribution of pelvis rotation to step length was negative at lower speeds, switching to positive at 3 km/h. With big steps, leg and pelvis were more in-phase, and the contribution of pelvis rotation to step length was always positive, and relatively large. Still, the overall contribution of pelvis rotations to step length was small, less than 3%. Regression analysis revealed that leg-pelvis relative phase predicted about 60% of the variance of this contribution. The results of the present study suggest that, during normal slow walking, pelvis rotations increase, rather than decrease, the vertical movements of the centre of mass. With large steps, this does not happen, because leg and pelvis are in-phase at all speeds. Finally, it has been suggested that patients with hip flexion limitation may use larger pelvis rotations to increase step length. This, however, may only work as long as the pelvis rotates in-phase with the leg. Copyright © 2013 Elsevier B.V. All rights reserved.

Associations Between Arterial Oxygen Saturation, Body Size and Limb Measurements Among High-Altitude Andean Children

PubMed Central

Pomeroy, Emma; Stock, Jay T; Stanojevic, Sanja; Miranda, J Jaime; Cole, Tim J; Wells, Jonathan CK

2013-01-01

Objectives The relative influences of hypoxia and other environmental stressors on growth at altitude remain unclear. Previous work demonstrated an association between peripheral arterial oxygen saturation (SpO2) and anthropometry (especially tibia length) among Tibetan and Han children at altitude. We investigated whether similar associations exist among Andeans, and the patterning of associations between SpO2 and anthropometry. Methods Stature, head-trunk height, total upper and lower limb lengths, zeugopod (ulna and tibia) and autopod (hand and foot) lengths were measured in Peruvian children (0.5–14 years) living at >3000 m altitude. SpO2 was measured by pulse oximetry. Anthropometry was converted to internal z scores. Correlation and multiple regression were used to examine associations between anthropometry z scores and SpO2, altitude, or SpO2 adjusted for altitude since altitude is a major determinant of variation in SpO2. Results SpO2 and altitude show weak, significant correlations with zeugopod length z scores and still weaker significant correlations with total upper and lower limb length z scores. Correlations with z scores for stature, head-trunk height, or autopod lengths are not significant. Adjusted for altitude, there is no significant association between anthropometry and SpO2. Conclusions Associations between SpO2 or altitude and total limb and zeugopod length z scores exist among Andean children. However, the relationships are relatively weak, and while the relationship between anthropometry and altitude may be partly mediated by SpO2, other factors that covary with altitude (e.g., socioeconomic status, health) are likely to influence anthropometry. The results support suggestions that zeugopod lengths are particularly sensitive to environmental stressors. Am. J. Hum. Biol., 25:629–636, 2013. © 2013 Wiley Periodicals, Inc. PMID:23904412

Mechanical and energetic consequences of rolling foot shape in human walking

PubMed Central

Adamczyk, Peter G.; Kuo, Arthur D.

2013-01-01

SUMMARY During human walking, the center of pressure under the foot progresses forward smoothly during each step, creating a wheel-like motion between the leg and the ground. This rolling motion might appear to aid walking economy, but the mechanisms that may lead to such a benefit are unclear, as the leg is not literally a wheel. We propose that there is indeed a benefit, but less from rolling than from smoother transitions between pendulum-like stance legs. The velocity of the body center of mass (COM) must be redirected in that transition, and a longer foot reduces the work required for the redirection. Here we develop a dynamic walking model that predicts different effects from altering foot length as opposed to foot radius, and test it by attaching rigid, arc-like foot bottoms to humans walking with fixed ankles. The model suggests that smooth rolling is relatively insensitive to arc radius, whereas work for the step-to-step transition decreases approximately quadratically with foot length. We measured the separate effects of arc-foot length and radius on COM velocity fluctuations, work performed by the legs and metabolic cost. Experimental data (N=8) show that foot length indeed has much greater effect on both the mechanical work of the step-to-step transition (23% variation, P=0.04) and the overall energetic cost of walking (6%, P=0.03) than foot radius (no significant effect, P>0.05). We found the minimum metabolic energy cost for an arc foot length of approximately 29% of leg length, roughly comparable to human foot length. Our results suggest that the foot's apparently wheel-like action derives less benefit from rolling per se than from reduced work to redirect the body COM. PMID:23580717

Mechanical and energetic consequences of rolling foot shape in human walking.

PubMed

Adamczyk, Peter G; Kuo, Arthur D

2013-07-15

During human walking, the center of pressure under the foot progresses forward smoothly during each step, creating a wheel-like motion between the leg and the ground. This rolling motion might appear to aid walking economy, but the mechanisms that may lead to such a benefit are unclear, as the leg is not literally a wheel. We propose that there is indeed a benefit, but less from rolling than from smoother transitions between pendulum-like stance legs. The velocity of the body center of mass (COM) must be redirected in that transition, and a longer foot reduces the work required for the redirection. Here we develop a dynamic walking model that predicts different effects from altering foot length as opposed to foot radius, and test it by attaching rigid, arc-like foot bottoms to humans walking with fixed ankles. The model suggests that smooth rolling is relatively insensitive to arc radius, whereas work for the step-to-step transition decreases approximately quadratically with foot length. We measured the separate effects of arc-foot length and radius on COM velocity fluctuations, work performed by the legs and metabolic cost. Experimental data (N=8) show that foot length indeed has much greater effect on both the mechanical work of the step-to-step transition (23% variation, P=0.04) and the overall energetic cost of walking (6%, P=0.03) than foot radius (no significant effect, P>0.05). We found the minimum metabolic energy cost for an arc foot length of approximately 29% of leg length, roughly comparable to human foot length. Our results suggest that the foot's apparently wheel-like action derives less benefit from rolling per se than from reduced work to redirect the body COM.

Associations between temporary employment and occupational injury: what are the mechanisms?

PubMed

Benavides, F G; Benach, J; Muntaner, C; Delclos, G L; Catot, N; Amable, M

2006-06-01

To determine whether observed higher risks of occupational injury among temporary workers are due to exposure to hazardous working conditions and/or to lack of job experience level. Data systematically recorded for 2000 and 2001 by the Spanish Ministry of Labour and Social Affairs on fatal and non-fatal traumatic occupational injuries were examined by type of employment and type of accident, while adjusting for gender, age, occupation, and length of employment in the company. In the study period there were 1500 fatal and 1 806 532 non-fatal traumatic occupational injuries that occurred at the workplace. Incidence rates and rate ratios (RR) were estimated using Poisson regression models. Temporary workers showed a rate ratio of 2.94 for non-fatal occupational injuries (95% CI 2.40 to 3.61) and 2.54 for fatal occupational injuries (95% CI 1.88 to 3.42). When these associations were adjusted by gender, age, occupation, and especially length of employment, they loose statistic significance: 1.05 (95% CI 0.97 to 1.12) for non-fatal and 1.07 (95% CI 0.91 to 1.26) for fatal. Lower job experience and knowledge of workplace hazards, measured by length of employment, is a possible mechanism to explain the consistent association between temporary workers and occupational injury. The role of working conditions associated with temporary jobs should be assessed more specifically.

Chlorinated paraffins wrapping of carbon nanotubes: A theoretical investigation

NASA Astrophysics Data System (ADS)

Ding, Qiuyue; Ding, Ning; Chen, Xiangfeng; Wu, Chi-Man Lawrence

2018-04-01

How nanomaterials interact with pollutants is the central for understanding their environmental behavior and practical application. In this work, molecular dynamics (MD) and density functional theoretical (DFT) methods were used to investigated the influence of carbon chain length, degree of chlorination, chain configuration, and chirality of chlorinated paraffin (CP) and diameter of single-walled carbon nanotubes (SWNTs) on the interaction between CPs and SWNTs. The simulation results demonstrated that CP chain length and chlorination degree played considerably important roles in determining interaction strength between SWNTs and CPs. The interaction energies increased with increasing chain length and chlorination degree. The chirality of SWNT exerted negligible influence on the interaction energy between SWNTs and CPs. On the contrary, interaction energy increased with increasing radius of SWNTs due to the surface curvatures. This result was rationalized by considering the decrease in SWNT curvature with increasing radius, which resulted in plane-like CNT wall. The negligible influence of CP chain configurations was attributed to relative flexibility of CP carbon chains, which can wrap on tubes through conformational changes with low-energy barriers. MD results indicated that CPs could adsorb on SWNT surface rapidly in aqueous environment. Charge transfer and electronic density results indicated that the interaction between CPs and SWNTs was physisorption in nature. This work provides fundamental information regarding SWNTs as sorbents for CPs extraction and adsorptive removal from environmental water system.

Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: the Multiethnic Study of Atherosclerosis (MESA).

PubMed

Fujishiro, Kaori; Diez-Roux, Ana V; Landsbergis, Paul A; Jenny, Nancy Swords; Seeman, Teresa

2013-08-01

Telomere length has been proposed as a biomarker of cell senescence, which is associated with a wide array of adverse health outcomes. While work is a major determinant of health, few studies have investigated the association of telomere length with various dimensions of occupation. Accelerated cellular aging could be a common pathway linking occupational exposure to several health outcomes. Leukocyte telomere length was assessed using quantitative PCR in a community-based sample of 981 individuals (age: 45-84 years). Questionnaires were used to collect information on current employment status, current or main occupation before retirement and job strain. The Occupational Resource Network (O*NET) database was linked to the questionnaire data to create five exposure measures: physical activity on the job, physical hazard exposure, interpersonal stressors, job control and job demands. Linear regression was used to estimate associations of occupational characteristics with telomere lengths after adjustment for age, sex, race, socioeconomic position and several behavioural risk factors. There were no mean differences in telomere lengths across current employment status, occupational category, job strain categories or levels of most O*NET exposure measures. There was also no evidence that being in lower status occupational categories or being exposed to higher levels of adverse physical or psychosocial exposures accelerated the association between age and telomere shortening. Cellular aging as reflected by shorter telomeres does not appear to be an important pathway linking occupation to various health outcomes.

Follow-up on family practice residents' perspectives on length and content of training.

PubMed

Duane, Marguerite; Dovey, Susan M; Klein, Lisa S; Green, Larry A

2004-01-01

The structure of family practice residency programs remains essentially unchanged from the model first proposed more than 35 years ago. Advances in medical technology and knowledge combined with increasing restrictions on resident work hours and decreasing medical student interest invite reconsideration of how family physicians are trained. We resurveyed 442 third-year family practice residents who had participated in a prior study in 2000 to determine whether their opinions about the length and content of residency had changed and whether they would still choose to be a physician and a family physician. Thirty-seven percent of responding third-year residents favored extending family practice residency to 4 years. Compared as groups, there was relatively little change in opinion between first- and third-year residents. However, residents' individual responses about the settings and content areas for which they would be willing to consider extending training varied considerably between years 1 and 3. Personal characteristics did not seem to influence residents' opinions about length and content of training. Reasons for favoring a 4-year program and barriers to change were similar to those reported previously. Residents' commitment to medicine and family medicine was still strong and was not associated with their opinions about length of training. Although most surveyed residents favored a 3-year residency program, a substantial minority still supported extending training to 4 years, and the majority would still choose to enter family medicine programs if they were extended. Given a lack of consensus about specific content areas, family medicine should consider a period of experimentation to determine how to best prepare future family physicians.

Real-time determination of sarcomere length of a single cardiomyocyte during contraction

PubMed Central

Kalda, Mari; Vendelin, Marko

2013-01-01

Sarcomere length of a cardiomyocyte is an important control parameter for physiology studies on a single cell level; for instance, its accurate determination in real time is essential for performing single cardiomyocyte contraction experiments. The aim of this work is to develop an efficient and accurate method for estimating a mean sarcomere length of a contracting cardiomyocyte using microscopy images as an input. The novelty in developed method lies in 1) using unbiased measure of similarities to eliminate systematic errors from conventional autocorrelation function (ACF)-based methods when applied to region of interest of an image, 2) using a semianalytical, seminumerical approach for evaluating the similarity measure to take into account spatial dependence of neighboring image pixels, and 3) using a detrend algorithm to extract the sarcomere striation pattern content from the microscopy images. The developed sarcomere length estimation procedure has superior computational efficiency and estimation accuracy compared with the conventional ACF and spectral analysis-based methods using fast Fourier transform. As shown by analyzing synthetic images with the known periodicity, the estimates obtained by the developed method are more accurate at the subpixel level than ones obtained using ACF analysis. When applied in practice on rat cardiomyocytes, our method was found to be robust to the choice of the region of interest that may 1) include projections of carbon fibers and nucleus, 2) have uneven background, and 3) be slightly disoriented with respect to average direction of sarcomere striation pattern. The developed method is implemented in open-source software. PMID:23255581

Rate constant for OH with selected large alkanes : shock-tube measurements and an improved group scheme.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sivaramakrishnan, R.; Michael, J. V.; Chemical Sciences and Engineering Division

High-temperature rate constant experiments on OH with the five large (C{sub 5}-C{sub 8}) saturated hydrocarbons n-heptane, 2,2,3,3-tetramethylbutane (2,2,3,3-TMB), n-pentane, n-hexane, and 2,3-dimethylbutane (2,3-DMB) were performed with the reflected-shock-tube technique using multipass absorption spectrometric detection of OH radicals at 308 nm. Single-point determinations at {approx}1200 K on n-heptane, 2,2,3,3-TMB, n-hexane, and 2,3-DMB were previously reported by Cohen and co-workers; however, the present work substantially extends the database to both lower and higher temperature. The present experiments span a wide temperature range, 789-1308 K, and represent the first direct measurements of rate constants at T > 800 K for n-pentane. The presentmore » work utilized 48 optical passes corresponding to a total path length of {approx}4.2 m. As a result of this increased path length, the high OH concentration detection sensitivity permitted pseudo-first-order analyses for unambiguously measuring rate constants.« less

Blurring out hydrogen: The dynamical structure of teflic acid

NASA Astrophysics Data System (ADS)

Herbers, S.; Obenchain, D. A.; Kraus, P.; Wachsmuth, D.; Grabow, J.-U.

2018-05-01

The microwave spectra of 10 teflic acid isotopologues were recorded in the frequency range of 3-25 GHz using supersonic jet-expansion Fourier transform microwave spectroscopy. Despite being asymmetric in its equilibrium structure, the delocalization of the hydrogen atom leads to a symmetric top vibrational ground state structure. In this work, we present the zero point structure obtained from the experimental rotational constants and an approach to determine the semi-experimental equilibrium structure aided by ab initio data. The Te-O bond length determined in the equilibrium structure is accurate to the picometer and can be used as a benchmark for computational methods treating relativistic effects.

20 CFR 668.350 - Are there any restrictions on allowable activities?

Code of Federal Regulations, 2010 CFR

2010-04-01

... working a similar length of time and doing the same type of work. (WIA sec. 181(b)(5).) (c) In addition... conditions at the same level and to the same extent as other employees working a similar length of time and... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Are there any restrictions on allowable...

Efficacy of different irrigation and activation systems on the penetration of sodium hypochlorite into simulated lateral canals and up to working length: an in vitro study.

PubMed

de Gregorio, Cesar; Estevez, Roberto; Cisneros, Rafael; Paranjpe, Avina; Cohenca, Nestor

2010-07-01

The removal of vital and necrotic pulp tissue, microorganisms, and their toxins is essential for endodontic success. However, the complex anatomy of the root canal system has limited our ability to debride it completely. Hence the purpose of this study was to evaluate the effect of currently used irrigation and activation systems on the penetration of sodium hypochlorite into simulated lateral canals and to working length in a closed system. One hundred single-rooted teeth were used in this study. A total of 600 simulated lateral canals were created, 6 in each tooth, with 2 lateral canals at 2, 4.5, and 6 mm of working length. To resemble the clinical situation, a closed system was created by coating each root with soft modeling wax. Roots were then randomly assigned to 4 experimental groups: group 1 (n = 20), Endoactivator (sonic activation); group 2 (n = 20), passive ultrasonic (PUI) activation; group 3 (n = 20), F file; group 4 (n = 20), apical negative pressure (ANP) irrigation; and control group 5 (n = 20), positive pressure irrigation. The samples were evaluated by direct observation of the images recorded under the dental operating microscope. The results demonstrated that the ANP irrigation group was superior at reaching working length, and PUI was the most effective at lateral canal penetration. The ANP irrigation system demonstrated limited activation of the irrigant into lateral canals but reached the working length significantly more than the other groups tested. In contrast, PUI group demonstrated significantly more penetration of irrigant into lateral canals but not up to the working length. Copyright 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Effect of repetitive pecking at working length for glide path preparation using G-file.

PubMed

Ha, Jung-Hong; Jeon, Hyo-Jin; Abed, Rashid El; Chang, Seok-Woo; Kim, Sung-Kyo; Kim, Hyeon-Cheol

2015-05-01

Glide path preparation is recommended to reduce torsional failure of nickel-titanium (NiTi) rotary instruments and to prevent root canal transportation. This study evaluated whether the repetitive insertions of G-files to the working length maintain the apical size as well as provide sufficient lumen as a glide path for subsequent instrumentation. The G-file system (Micro-Mega) composed of G1 and G2 files for glide path preparation was used with the J-shaped, simulated resin canals. After inserting a G1 file twice, a G2 file was inserted to the working length 1, 4, 7, or 10 times for four each experimental group, respectively (n = 10). Then the canals were cleaned by copious irrigation, and lubricated with a separating gel medium. Canal replicas were made using silicone impression material, and the diameter of the replicas was measured at working length (D0) and 1 mm level (D1) under a scanning electron microscope. Data was analysed by one-way ANOVA and post-hoc tests (p = 0.05). The diameter at D0 level did not show any significant difference between the 1, 2, 4, and 10 times of repetitive pecking insertions of G2 files at working length. However, 10 times of pecking motion with G2 file resulted in significantly larger canal diameter at D1 (p < 0.05). Under the limitations of this study, the repetitive insertion of a G2 file up to 10 times at working length created an adequate lumen for subsequent apical shaping with other rotary files bigger than International Organization for Standardization (ISO) size 20, without apical transportation at D0 level.

The ionization length in plasmas with finite temperature ion sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jelic, N.; Kos, L.; Duhovnik, J.

2009-12-15

The ionization length is an important quantity which up to now has been precisely determined only in plasmas which assume that the ions are born at rest, i.e., in discharges known as 'cold ion-source' plasmas. Presented here are the results of our calculations of the ionization lengths in plasmas with an arbitrary ion source temperature. Harrison and Thompson (H and T) [Proc. Phys. Soc. 74, 145 (1959)] found the values of this quantity for the cases of several ion strength potential profiles in the well-known Tonks-Langmuir [Phys. Rev. 34, 876 (1929)] discharge, which is characterized by 'cold' ion temperature. Thismore » scenario is also known as the 'singular' ion-source discharge. The H and T analytic result covers cases of ion sources proportional to exp(betaPHI) with PHI the normalized plasma potential and beta=0,1,2 values, which correspond to particular physical scenarios. Many years following H and T's work, Bissell and Johnson (B and J) [Phys. Fluids 30, 779 (1987)] developed a model with the so-called 'warm' ion-source temperature, i.e., 'regular' ion source, under B and J's particular assumption that the ionization strength is proportional to the local electron density. However, it appears that B and J were not interested in determining the ionization length at all. The importance of this quantity to theoretical modeling was recognized by Riemann, who recently answered all the questions of the most advanced up-to-date plasma-sheath boundary theory with cold ions [K.-U. Riemann, Phys. Plasmas 13, 063508 (2006)] but still without the stiff warm ion-source case solution, which is highly resistant to solution via any available analytic method. The present article is an extension of H and T's results obtained for a single point only with ion source temperature T{sub n}=0 to arbitrary finite ion source temperatures. The approach applied in this work is based on the method recently developed by Kos et al. [Phys. Plasmas 16, 093503 (2009)].« less

A new clustering of antibody CDR loop conformations

PubMed Central

North, Benjamin; Lehmann, Andreas; Dunbrack, Roland L.

2010-01-01

Previous analyses of the complementarity determining regions (CDRs) of antibodies have focused on a small number of “canonical” conformations for each loop. This is primarily the result of the work of Chothia and colleagues, most recently in 1997. Because of the widespread utility of antibodies, we have revisited the clustering of conformations of the six CDR loops with the much larger amount of structural information currently available. In this work, we were careful to use a high-quality data set by eliminating low-resolution structures and CDRs with high B-factors or high conformational energies. We used a distance function based on directional statistics and an effective clustering algorithm using affinity propagation. With this data set of over 300 non-redundant antibody structures, we were able to cover 28 CDR-length combinations (e.g., L1 length 11, or “L1-11” in our nomenclature) for L1, L2, L3, H1 and H2. The Chothia analysis covered only 20 CDR-lengths. Only four of these had more than one conformational cluster, of which two could easily be distinguished by gene source (mouse/human; κ/λ) and one purely by the presence and positions of Pro residues (L3-9). Thus using the Chothia analysis does not require the complicated set of “structure-determining residues” that is often assumed. Of our 28 CDR-lengths, 15 of them have multiple conformational clusters including ten for which Chothia had only one canonical class. We have a total of 72 clusters for the non-H3 CDRs; approximately 85% of the non-H3 sequences can be assigned to a conformational cluster based on gene source and/or sequence. We found that earlier predictions of “bulged” vs. “non-bulged” conformations based on the presence or absence of anchor residues Arg/Lys94 and Asp101 of H3 have not held up, since all four combinations lead to a majority of conformations that are bulged. Thus the earlier analyses have been significantly enhanced by the increased data. We believe the new classification will lead to improved methods for antibody structure prediction and design. PMID:21035459

Vibration control in statically indeterminate adaptive truss structures

NASA Technical Reports Server (NTRS)

Baycan, C. M.; Utku, Senol; Wada, Ben K.

1993-01-01

In this work vibration control of statically indeterminate adaptive truss structures is investigated. Here, the actuators (i.e., length adjusting devices) that are used for vibration control, work against the axial forces caused by the inertial forces. In statically determinate adaptive trusses no axial force is induced by the actuation. The control problem in statically indeterminate trusses may be dominated by the actuation-induced axial element forces. The creation of actuation-induced axial forces puts the system to a higher energy state, thus aggravates the controls. It is shown that by the usage of sufficient number of slave actuators in addition to the actual control actuators, the actuation-induced axial element forces can be nullified, and the control problem of the statically indeterminate adaptive truss problem is reduced to that of a statically determinate one. It is also shown that the usage of slave actuators saves a great amount of control energy and provides robustness for the controls.

The roles of productivity and ecosystem size in determining food chain length in tropical terrestrial ecosystems.

PubMed

Young, Hillary S; McCauley, Douglas J; Dunbar, Robert B; Hutson, Michael S; Ter-Kuile, Ana Miller; Dirzo, Rodolfo

2013-03-01

Many different drivers, including productivity, ecosystem size, and disturbance, have been considered to explain natural variation in the length of food chains. Much remains unknown about the role of these various drivers in determining food chain length, and particularly about the mechanisms by which they may operate in terrestrial ecosystems, which have quite different ecological constraints than aquatic environments, where most food chain length studies have been thus far conducted. In this study, we tested the relative importance of ecosystem size and productivity in influencing food chain length in a terrestrial setting. We determined that (1) there is no effect of ecosystem size or productive space on food chain length; (2) rather, food chain length increases strongly and linearly with productivity; and (3) the observed changes in food chain length are likely achieved through a combination of changes in predator size, predator behavior, and consumer diversity along gradients in productivity. These results lend new insight into the mechanisms by which productivity can drive changes in food chain length, point to potential for systematic differences in the drivers of food web structure between terrestrial and aquatic systems, and challenge us to consider how ecological context may control the drivers that shape food chain length.

Evaluation of infiltration for the determination of palms water needs

NASA Astrophysics Data System (ADS)

Benlarbi, Dalila; Boutaoutaou, Djamel; Saggaï, Sofiane

2018-05-01

In arid climate conditions, irrigation water requirements increase, but available water resources are limited. And therefore the Saharan regions, large consumers of water can be seriously threatened if they do not make the necessary to become as parsimonious as allow the irrigation techniques whose technological aspect on their improvement has been privileged until now but all the problems are not solved. The objective of this work is to know the process of infiltration of water in the soil, i.e.: to try to determine exactly its value with obtaining the best combination (flow of entry, board length and irrigation time) in order to have a more or less uniform distribution in the soil and especially by avoiding significant water losses that would cause rise in the water table. The infiltration will allow us to calculate at any point the dose of water received that we will compare with the needs of the date palm. For this purpose; we varied the input flow for a constant board length. Then we varied the board length for a constant input rate. In both cases we varied the irrigation time according to the water requirements of the date palm. The flow remains of course constant during the entire feeding period. This study is primarily experimental and aims to meet practical applications but not immediately because it is necessary to continue the experiments with several other combinations to achieve practical results.

In situ XANES and EXAFS Analysis of Redox Active Fe Center Ionic Liquids

DOE PAGES

Apblett, Christopher A.; Stewart, David M.; Fryer, Robert T.; ...

2015-10-23

We apply in situ X-Ray Absorption Near Edge Spectroscopy (XANES) and Extended X-Ray Absorption Fine Structure (EXAFS) techniques to a metal center ionic liquid undergoing oxidation and reduction in a three electrode spectroscopic cell. Furthermore, the determination of the extent of reduction under negative bias on the working electrode and the extent of oxidation are determined after pulse voltammetry to quiescence. While the ionic liquid undergoes full oxidation, it undergoes only partial reduction, likely due to transport issues on the timescale of the experiment. Nearest neighbor Fe-O distances in the fully oxidized state match well to expected values for similarlymore » coordinated solids, but reduction does not result in an extension of the Fe-O bond length, as would be expected from comparisons to the solid phase. Instead, little change in bond length is observed. Finally, we suggest that this may be due to a more complex interaction between the monodentate ligands of the metal center anion and the surrounding charge cloud, rather than straightforward electrostatics between the metal center and the nearest neighbor grouping.« less

76 FR 9749 - Affirmative Preliminary Determination of Circumvention of the Antidumping Duty Order on Certain...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

... certain cut-to-length carbon steel plate products with 0.0008 percent or more boron, by weight, regardless... Determination of Circumvention of the Antidumping Duty Order on Certain Cut-to-Length Carbon Steel Plate From...-to-length carbon steel plate from the PRC. [[Page 9750

Temperature fluctuations and the thermodynamic determination of the cooperativity length in glass forming liquids.

PubMed

Chua, Y Z; Zorn, R; Holderer, O; Schmelzer, J W P; Schick, C; Donth, E

2017-03-14

The aim of this paper is to decide which of the two possible thermodynamic expressions for the cooperativity length in glass forming liquids is the correct one. In the derivation of these two expressions, the occurrence of temperature fluctuations in the considered nanoscale subsystems is either included or neglected. Consequently, our analysis gives also an answer to the widely discussed problem whether temperature fluctuations have to be generally accounted for in thermodynamics or not. To this end, the characteristic length-scales at equal times and temperatures for propylene glycol were determined independently from AC calorimetry in both the above specified ways and from quasielastic neutron scattering (QENS), and compared. The result shows that the cooperative length determined from QENS coincides most consistently with the cooperativity length determined from AC calorimetry measurements for the case that the effect of temperature fluctuations is incorporated in the description. This conclusion indicates that-accounting for temperature fluctuations-the characteristic length can be derived by thermodynamic considerations from the specific parameters of the liquid at glass transition and that temperature does fluctuate in small systems.

Temperature fluctuations and the thermodynamic determination of the cooperativity length in glass forming liquids

NASA Astrophysics Data System (ADS)

Chua, Y. Z.; Zorn, R.; Holderer, O.; Schmelzer, J. W. P.; Schick, C.; Donth, E.

2017-03-01

The aim of this paper is to decide which of the two possible thermodynamic expressions for the cooperativity length in glass forming liquids is the correct one. In the derivation of these two expressions, the occurrence of temperature fluctuations in the considered nanoscale subsystems is either included or neglected. Consequently, our analysis gives also an answer to the widely discussed problem whether temperature fluctuations have to be generally accounted for in thermodynamics or not. To this end, the characteristic length-scales at equal times and temperatures for propylene glycol were determined independently from AC calorimetry in both the above specified ways and from quasielastic neutron scattering (QENS), and compared. The result shows that the cooperative length determined from QENS coincides most consistently with the cooperativity length determined from AC calorimetry measurements for the case that the effect of temperature fluctuations is incorporated in the description. This conclusion indicates that—accounting for temperature fluctuations—the characteristic length can be derived by thermodynamic considerations from the specific parameters of the liquid at glass transition and that temperature does fluctuate in small systems.

Size Determination of Y2O3 Crystallites in MgO Composite Using Mie Scattering

DTIC Science & Technology

2017-11-07

particle size, and the path length through the material to generate an expected light transmission spectrum. These calculated curves were compared to...materials. In the current work, light transmission data are compared to the theoretical curves generated by the Mie scattering model in an attempt to...Since the authors wanted to compare the model’s predictions to the experimental %T values, it seemed logical to start with Beer’s Law: )exp()1( 2

Polarization Considerations for the Laser Interferometer Space Antenna

NASA Technical Reports Server (NTRS)

Waluschka, Eugene; Pedersen, Tracy R.; McNamara, Paul

2005-01-01

A polarization ray trace model of the Laser Interferometer Space Antenna s (LISA) optical path is being created. The model will be able to assess the effects of various polarizing elements and the optical coatings on the required, very long path length, picometer level dynamic interferometry. The computational steps are described. This should eliminate any ambiguities associated with polarization ray tracing of interferometers and provide a basis for determining the computer model s limitations and serve as a clearly defined starting point for future work.

Protective determinants of sickness absence among employees with multisite pain-a 7-year follow-up.

PubMed

Haukka, Eija; Ojajärvi, Anneli; Kaila-Kangas, Leena; Leino-Arjas, Päivi

2017-02-01

We identified factors protective of all-cause sickness absence (SA) among subjects with multisite musculoskeletal pain (MSP). The nationally representative source sample comprised 3420 actively working Finns aged 30 to 55 in year 2000 and alive at follow-up. Pain in 18 body locations was combined into four sites (neck, low back, upper limbs, and lower limbs). The baseline prevalence of MSP (pain in ≥ 2 sites) was 32%. Baseline data on sociodemographic factors, work ability, work, health, and lifestyle were gathered by questionnaire, interview, and clinical examination and linked with national registers on all-cause SA (periods lasting ≥10 workdays) for 2002 to 2008. Based on trajectory analysis, 74% of those with MSP had a low and 26% a high probability of SA. In logistic regression analysis, younger age, male sex, and professional occupational group were inversely associated with SA. Allowing for these, good physician-assessed work ability, physically light work, possibility to adjust workday length, encouraging workplace atmosphere, no problems with working community or mental stress, normal weight, and no sleep disorders were predictive of lower SA rates (odds ratios between 0.47 and 0.70). In a final stepwise model adjusted for age, sex, and occupational group, no exposure to lifting (odds ratio 0.58, 95% confidence interval 0.39-0.85) and to repetitive hand movements (0.57, 0.39-0.83), possibility to adjust workday length (0.73, 0.53-0.99), and normal weight (0.59, 0.40-0.87) were inversely associated with SA. In conclusion, several modifiable factors related to work and lifestyle were found as predictive of lower rates of longer SA among occupationally active subjects with MSP.

Long-term military work outcomes in soldiers who become mental health casualties when deployed on operations.

PubMed

Jones, Norman; Fear, Nicola T; Jones, Margaret; Wessely, Simon; Greenberg, Neil

2010-01-01

little is known about longer term military work outcomes in UK military personnel who develop mental health problems when operationally deployed. Deployed Field Mental Health Teams (FMHTs) who support them follow the principles of "Forward Psychiatry," aiming to treat psychiatric casualties close to the front line to maximize operational effectiveness and occupational retention. to examine the short- and long-term military work outcomes in soldiers deployed to Iraq between 2003 and 2007 who were referred to the FMHT. FMHT clinical records were linked to occupational records with 825 resulting matches. 71.6% of the referred soldiers with a documented short-term military work outcome returned to their operational unit, and 73.5% of those who had a documented long-term military work outcome served on for a period in excess of two years. Adjusting for potential confounders, a shorter service length and removal from the operational theatre were both strongly associated with premature discharge; however, it was not possible to determine the severity of the presenting mental health problem and assess whether this impacted outcome. the results of this study support the use of the Forward Psychiatry principles in achieving good short-term military work outcomes. Utilizing these principles, three-quarters of those referred to the FMHT were returned to their deployed unit and approximately three-quarters of those assessed by the FMHT remained in service two years after referral. We suggest that these are positive work outcomes; however, being evacuated out of the operational environment and having a short service length were both associated with premature discharge, though we were unable to examine the role of illness severity.

A comparison of Kodak Ultraspeed and Ektaspeed Plus dental X-ray films for use in endodontics.

PubMed

Moule, A J; Wong, A; Monsour, P A; Basford, K E

2001-06-01

The advantage of using a faster film for length determination in endodontic therapy is obvious. However, for such a film to be generally accepted, it must demonstrate comparable diagnostic quality to traditionally used films. The comparative accuracy of canal length determination of Ultraspeed and Ektaspeed Plus dental X-ray films was assessed in maxillary first and second molars; for different canals, for different teeth, for different exposures, and for different examiners (five general dentists and three endodontic specialists). In general, there were no significant differences between films, among examiners, or any interaction between films and exposures. That is, an assessor's ability to estimate lengths was not significantly influenced by the film type or by exposure used. There was a wide divergence in the individual assessor's ability to estimate lengths. Specialists estimated lengths more accurately than general practitioners and estimated lengths more accurately with Ektaspeed Plus film. Length determination in distobuccal and mesiobuccal canals was more accurate than in palatal canals. Most palatal canals were underestimated in length by more than 1mm. The use of file sizes larger in number than size 15 is recommended in these canals. For length determination, Ektaspeed Plus dental X-ray film is as effective as Ultraspeed film. Given the acceptable quality and accuracy of Ektaspeed Plus film, there seems to be no clinical reason to subject patients to greater radiation by using a slower film during endodontic therapy.

Effect of working conditions on non-work-related sickness absence.

PubMed

Sampere, M; Gimeno, D; Serra, C; Plana, M; Martínez, J M; Delclos, G L; Benavides, F G

2012-01-01

There is limited evidence of the role of working conditions as prognostic factors for non-work-related sickness absence (i.e. absence due to injuries or diseases of non-occupational origin). To analyse the association between working conditions and time to return to work (RTW) in workers with long-term (>15 days) non-work-related sickness absence. We followed up a total of 655 workers, who completed a baseline questionnaire including physical and psychosocial work factors, until their non-work-related long-term sickness absence ended. Time to RTW was determined based on the health insurance company register. Cox proportional hazard models were constructed to evaluate the associations between working conditions and time to RTW. A self-perceived high level of physical activity at work and work with back twisted or bent were related to longer duration of sickness absence. We did not find any strong evidence of associations between psychosocial work factors and time to RTW, although higher job insecurity and low reward showed marginal statistical significance. Hazardous physical working conditions are associated with longer duration of non-work-related sickness absence. Workplace ergonomic interventions could conceivably shorten the length of sickness absence that has not originated at work.

Determinants of sick-leave length: still limited to diagnosis elements.

PubMed

Lévy, Yvan; Denis, Angélique; Fassier, Jean-Baptiste; Kellou, Nadir; Schott, Anne-Marie; Letrilliart, Laurent

2017-12-01

Sickness certification implies that a health problem impairs ability to work. However, its assessment is seldom performed by physicians. Our objective was, therefore, to assess the specific influence of functional and environmental limitations on the length of sick-leave prescriptions. We conducted a cross-sectional study in French general teaching practices and recorded 353 initial sick-leave certifications. For each of them, the functional and environmental limitations were collected using the ATCIF questionnaire, derived from the International Classification of Functioning. Data analysis was based on a linear regression multivariate model. Among the functional limitations, "pain" was the main body function impairment (22% of impairments) and "mobility" the main activity limitation (48%). An environmental barrier was identified in 39% of sick-listed patients, mainly relating to "products and technology" (20%), which refers to workplace factors. The prescription was longer in cases of activity limitations relating to "mobility" and in cases of environmental barriers relating to "products and technology". The multivariate model explained 27% of the variability of sick-leave length through diagnosis elements and only 7% through functional and contextual elements. In sick-leave prescription, a functional and contextual approach, in addition to the traditional diagnosis-based approach, could better support patients' shared understanding and follow-up, and accountability towards health authorities. Implication for Rehabilitation Although sickness certification implies that a health problem impairs ability to work, decision on sick-leave length in general practice is primarily based on diagnosis. A more functional and contextual approach could better support patients' and other health professionals' shared understanding and follow-up, and accountability towards health authorities. Such evolution requires a change of paradigm in medical education, and the way of reasoning of healthcare professionals.

Evaluation and clinical significance of the stomach age model for evaluating aging of the stomach-a multicenter study in China

PubMed Central

2014-01-01

Background A higher prevalence of chronic atrophic gastritis (CAG) occurs in younger adults in Asia. We used Stomach Age to examine the different mechanisms of CAG between younger adults and elderly individuals, and established a simple model of cancer risk that can be applied to CAG surveillance. Methods Stomach Age was determined by FISH examination of telomere length in stomach biopsies. Δψm was also determined by flow cytometry. Sixty volunteers were used to confirm the linear relationship between telomere length and age while 120 subjects were used to build a mathematical model by a multivariate analysis. Overall, 146 subjects were used to evaluate the validity of the model, and 1,007 subjects were used to evaluate the relationship between prognosis and Δage (calculated from the mathematical model). ROC curves were used to evaluate the relationship between prognosis and Δage and to determine the cut-off point for Δage. Results We established that a tight linear relationship between the telomere length and the age. The telomere length was obvious different between patients with and without CAG even in the same age. Δψm decreased in individuals whose Stomach Age was greater than real age, especially in younger adults. A mathematical model of Stomach Age (real age + Δage) was successfully constructed which was easy to apply in clinical work. A higher Δage was correlated with a worse outcome. The criterion of Δage >3.11 should be considered as the cut-off to select the subgroup of patients who require endoscopic surveillance. Conclusion Variation in Stomach Age between individuals of the same biological age was confirmed. Attention should be paid to those with a greater Stomach Age, especially in younger adults. The Δage in the Simple Model can be used as a criterion to select CAG patients for gastric cancer surveillance. PMID:25057261

Detecting the propagation effect of terahertz wave inside the two-color femtosecond laser filament in the air

NASA Astrophysics Data System (ADS)

Zhao, J.; Zhang, X.; Li, S.; Liu, C.; Chen, Y.; Peng, Y.; Zhu, Y.

2018-03-01

In this work, to decide the existence of terahertz (THz) wave propagation effect, THz pulses emitted from a blocked two-color femtosecond laser filament with variable length were recorded by a standard electric-optic sampling setup. The phenomenon of temporal advance of the THz waveform's peak with the increasing filament length has been observed. Together with another method of knife-edge measurement which aims at directly retrieving the THz beam diameter, both the experimental approaches have efficiently indicated the same filament range within which THz wave propagated inside the plasma column. At last, a preliminary two-dimensional near-field scanning imaging of the THz spot inside the cross section of the filament has been suggested as the third way to determine the issue of THz wave propagation effect.

Physiological work performance in chronic low back disability: effects of a progressive activity program.

PubMed

Thomas, L K; Hislop, H J; Waters, R L

1980-04-01

Fifteen patients were tested before and after treatment in a multifaceted inpatient program for chronic low back pain to determine if a gradually progressive activity program affected gait performance and physiological capacity. Before treatment, all patients demonstrated decreased physiological conditioning by higher-than-expected values for oxygen consumption and heart rate and by lower-than-normal gait velocity, stride length, and cadence. After treatment, an increase in mean walking velocity of 19 meters/minute reflected parallel gains in cadence and stride length. Improved mechanical performance resulted in improved "energetics." Energy spent per unit of distance walked decreased by 18 percent after treatment, providing a useful measure of increased physiological efficiency. Results indicated that patients with chronic low back disability can derive significant conditioning effects from an exercise program based on general function.

Current-controlled curvature of coated micromirrors

NASA Astrophysics Data System (ADS)

Liu, Wei; Talghader, Joseph J.

2003-06-01

Precise control of micromirror curvature is critical in many optical microsystems. Micromirrors with current-controlled curvature are demonstrated. The working principle is that resistive heating changes the temperature of the micromirrors and thermal expansion induces a controlled curvature whose magnitude is determined by coating design. For example, for wide focal-length tuning, the radius of curvature of a gold-coated mirror was tuned from 2.5 to 8.2 mm over a current-induced temperature range from 22° to 72 °C. For fine focal-length tuning, the radius of curvature of a dielectric-coated (SiO2/Y2O3 λ/4 pairs) mirror was tuned from -0.68 to -0.64 mm over a current-induced temperature range from 22 to 84 °C. These results should be readily extendable to mirror flattening or real-time adaptive shape control.

[The characteristics of allocation of voluntary medical insurance of working population in Russia].

PubMed

Ankudinov, A B; Lebedev, O V

2016-01-01

The article presents the results of analysis of widespread of prevalence of additional medical services and voluntary medical insurance of working population of Russia. The quantitative values were received concerning widespread of disposal to Russian workers of various industries of social benefits on partial and full payment of treatment, degree of participation of workers in programs of voluntary medical insurance. It is demonstrated that besides sectorial characteristics the determinants of widespread of granting additional medical insurance are positioned as individual characteristics of workers and such obstacles as length of service, education, salary of worker, type of residence settlement, harmful and dangerous conditions of labor, type of property of enterprise (public/non-public).

Sex-specific differences in the synaptonemal complex in the genus Oreochromis (Cichlidae).

PubMed

Campos-Ramos, Rafael; Harvey, Simon C; Penman, David J

2009-04-01

Total synaptonemal complex (SC) lengths were estimated from Oreochromis aureus Steindachner (which has a WZ/ZZ sex determination system), O. mossambicus Peters and O. niloticus L. (both of which have XX/XY sex determination systems). The total SC length in oocytes was greater than that in spermatocytes in all three species (194 +/- 30 microm and 134 +/- 13 microm, 187 +/- 22 microm and 127 +/- 17 microm, 193 +/- 37 microm and 144 +/- 19 microm, respectively). These sex-specific differences did not appear to be influenced by the type of sex determination system (the female/male total SC length ratio was 1.45 in O. aureus, 1.47 in O. mossambicus and 1.34 in O. niloticus) and do not correlate with the lack of any overall sex-specific length differences in the current Oreochromis linkage map. Although based on data from relatively few species, there appears to be no consistent relationship between sex-specific SC lengths and linkage map lengths in fish. Neomale (hormonally masculinized genetic female) O. aureus and O. mossambicus had total SC lengths of 138 +/- 13 microm and 146 +/- 13 microm respectively, more similar to normal males than to normal females. These findings agree with data from other vertebrate species that suggest that phenotypic sex, rather than genotype, determines traits such as total SC length, chiasmata position and recombination pattern, at least for the autosomes.

Extension of the Viscous Collision Limiting Direct Simulation Monte Carlo Technique to Multiple Species

NASA Technical Reports Server (NTRS)

Liechty, Derek S.; Burt, Jonathan M.

2016-01-01

There are many flows fields that span a wide range of length scales where regions of both rarefied and continuum flow exist and neither direct simulation Monte Carlo (DSMC) nor computational fluid dynamics (CFD) provide the appropriate solution everywhere. Recently, a new viscous collision limited (VCL) DSMC technique was proposed to incorporate effects of physical diffusion into collision limiter calculations to make the low Knudsen number regime normally limited to CFD more tractable for an all-particle technique. This original work had been derived for a single species gas. The current work extends the VCL-DSMC technique to gases with multiple species. Similar derivations were performed to equate numerical and physical transport coefficients. However, a more rigorous treatment of determining the mixture viscosity is applied. In the original work, consideration was given to internal energy non-equilibrium, and this is also extended in the current work to chemical non-equilibrium.

Aging and cardiovascular complexity: effect of the length of RR tachograms

PubMed Central

Nagaraj, Nithin

2016-01-01

As we age, our hearts undergo changes that result in a reduction in complexity of physiological interactions between different control mechanisms. This results in a potential risk of cardiovascular diseases which are the number one cause of death globally. Since cardiac signals are nonstationary and nonlinear in nature, complexity measures are better suited to handle such data. In this study, three complexity measures are used, namely Lempel–Ziv complexity (LZ), Sample Entropy (SampEn) and Effort-To-Compress (ETC). We determined the minimum length of RR tachogram required for characterizing complexity of healthy young and healthy old hearts. All the three measures indicated significantly lower complexity values for older subjects than younger ones. However, the minimum length of heart-beat interval data needed differs for the three measures, with LZ and ETC needing as low as 10 samples, whereas SampEn requires at least 80 samples. Our study indicates that complexity measures such as LZ and ETC are good candidates for the analysis of cardiovascular dynamics since they are able to work with very short RR tachograms. PMID:27957395

Numerical study of the medium thickness in the Z-scan technique

NASA Astrophysics Data System (ADS)

Severiano Carrillo, I.; Méndez Otero, M. M.; Arroyo Carrasco, M. L.; Iturbe Castillo, M. D.

2011-09-01

The optical characterization of nonlinear media through the Z-scan technique considers initially a thin medium (with a thickness much less than the beam depth of focus). It has been observed that increasing the thickness of the medium the transmittance increases, this means that n2 increases, for this reason we will present a numerical model to determinate the minimum thin and the maximum thick medium limit. A thin medium is considered as a thin lens with focal length F1 and a thick medium can be regarded as a set of such thin lenses set with focal lengths F2, these lenses are contained in a medium whit a refraction index different than air. This analysis is made through Matlab using the theory of Gaussian beams, ABCD matrices and the q parameter, elementary theory in the development of this work, where the main feature of this model is that the nonlinearity type of the medium is considered as an integer constant in its focal length3. We present the graphs obtained from Z-scan for thick medium with both thermal and Kerr nonlinearities.

Compliant walking appears metabolically advantageous at extreme step lengths.

PubMed

Kim, Jaehoon; Bertram, John E A

2018-05-19

Humans alter gait in response to unusual gait circumstances to accomplish the task of walking. For instance, subjects spontaneously increase leg compliance at a step length threshold as step length increases. Here we test the hypothesis that this transition occurs based on the level of energy expenditure, where compliant walking becomes less energetically demanding at long step lengths. To map and compare the metabolic cost of normal and compliant walking as step length increases. 10 healthy individuals walked on a treadmill using progressively increasing step lengths (100%, 120%, 140% and 160% of preferred step length), in both normal and compliant leg walking as energy expenditure was recorded via indirect calorimetry. Leg compliance was controlled by lowering the center-of-mass trajectory during stance, forcing the leg to flex and extend as the body moved over the foot contact. For normal step lengths, compliant leg walking was more costly than normal walking gait, but compliant leg walking energetic cost did not increase as rapidly for longer step lengths. This led to an intersection between normal and compliant walking cost curves at 114% relative step length (regression analysis; r 2  = 0.92 for normal walking; r 2  = 0.65 for compliant walking). Compliant leg walking is less energetically demanding at longer step lengths where a spontaneous shift to compliant walking has been observed, suggesting the human motor control system is sensitive to energetic requirements and will employ alternate movement patterns if advantageous strategies are available. The transition could be attributed to the interplay between (i) leg work controlling body travel during single stance and (ii) leg work to control energy loss in the step-to-step transition. Compliant leg walking requires more stance leg work at normal step lengths, but involves less energy loss at the step-to-step transition for very long steps. Copyright © 2018 Elsevier B.V. All rights reserved.

Does Day Length Affect Winter Bird Distribution? Testing the Role of an Elusive Variable

PubMed Central

Carrascal, Luis M.; Santos, Tomás; Tellería, José L.

2012-01-01

Differences in day length may act as a critical factor in bird biology by introducing time constraints in energy acquisition during winter. Thus, differences in day length might operate as a main determinant of bird abundance along latitudinal gradients. This work examines the influence of day length on the abundance of wintering crested tits (Lophophanes cristatus) in 26 localities of Spanish juniper (Juniperus thurifera) dwarf woodlands (average height of 5 m) located along a latitudinal gradient in the Spanish highlands, while controlling for the influence of food availability, minimum night temperature, habitat structure and landscape characteristics. Top regression models in the AIC framework explained 56% of variance in bird numbers. All models incorporated day length as the variable with the highest magnitude effect. Food availability also played an important role, although only the crop of ripe juniper fruits, but not arthropods, positively affected crested tit abundance. Differences in vegetation structure across localities had also a strong positive effect (average tree height and juniper tree density). Geographical variation in night temperature had no influence on crested tit distribution, despite the low winter temperatures reached in these dwarf forests. This paper demonstrates for the first time that winter bird abundance increases with day length after controlling for the effect of other environmental variables. Winter average difference in day length was only 10.5 minutes per day along the 1°47′ latitudinal interval (190 km) included in this study. This amount of time, which reaches 13.5 h accumulated throughout the winter season, appears to be large enough to affect the long-term energy budget of small passerines during winter and to shape the distribution of winter bird abundance under restrictive environmental conditions. PMID:22393442

The impact of deployment length on the health and well-being of military personnel: a systematic review of the literature.

PubMed

Buckman, Joshua E J; Sundin, Josefin; Greene, Talya; Fear, Nicola T; Dandeker, Christopher; Greenberg, Neil; Wessely, Simon

2011-01-01

To determine the current state of knowledge regarding the effects of deployment length and a 'mismatch' between the expected and actual length of deployments on the health and well-being of military personnel in order to draw relevant conclusions for all organisations that deploy personnel to conflict zones. A systematic review was conducted of studies measuring deployment length to theatres of operations and the issue of 'mismatch' between expected and actual tour lengths. The nine studies included were rated for quality. Of the nine studies reviewed, six were rated as high quality, two as moderate quality and one as low quality. Seven of these studies found adverse effects of longer deployments on health and well-being. The two studies that measured 'mismatch' found adverse effects on mental health and well-being when deployments lasted longer than personnel expected. There are a limited number of studies which have assessed the effects of deployment length and very few that have assessed the effects of 'mismatch' on health and well-being. However, this review suggests that, as deployment length increases, the potential for personnel to suffer adverse health effects also increases. Further research is required to investigate the effects of spending prolonged periods of time away from family and friends, especially when deployment lasts longer than expected by personnel. These results are important not only for the Armed Forces, but also for other organisations that place employees in similar working conditions. Taking account of these findings may allow better preparation for the potentially harmful effects that deployments can have on employees' health and well-being.

[The length of the piston in otosclerosis surgery].

PubMed

Portmann, D; Alcantara, M; Vianna, M

2007-01-01

The measurement of the piston is always described as a significant stage of the surgery but its length is never clearly defined. The goal of this work is to determine the length of the prosthesis. From May 2003 to May 2005, 128 patients with otosclerosis, diagnosed on the basis of their clinical history and their audiogram, were included in this prospective study. Some of them were revision surgeries. The prosthesis generally used was the Portmann piston clip (Medtronic Xomed Inc Portmann Piston Clip Stainless Steel/Fluoroplastic). In stapedectomies, a Teflon piston of 0.6 mm of diameter was used (Pouret Company Fluoroplastic Stapes Prosthesis). These prostheses must be trimmed before their installation. The measurement technique is described. The length of the prosthesis was increased by 0.5 mm to include the thickness of the footplate. The Portmann piston clip was used 116 times (100 initial surgeries and 16 revisions surgeries) and the Teflon prosthesis of 0.6 mm of diameter only 13 times (6 primary stapedectomies and 7 revisions stapedectomies). The length of the prosthesis was between 3,5 mm and 5 mm. In the majority of cases, the length of the prosthesis was 4.75 mm (62 patients, 48.1%), followed by 4.5 mm (29 patients, 22.5%) and 5 mm (27 patients, 20.9%). In eleven cases (8.5%) the prosthesis measured less than 4,5 mm. None of the patients in this study experienced a postoperative sensorineural hearing loss. The measurement of the length of the piston is very significant, and in our study the majority of the pistons were cut at 4.75 mm which indicates an incus-footplate measurement of 4.25 mm.

Geostatistics and the representative elementary volume of gamma ray tomography attenuation in rocks cores

USGS Publications Warehouse

Vogel, J.R.; Brown, G.O.

2003-01-01

Semivariograms of samples of Culebra Dolomite have been determined at two different resolutions for gamma ray computed tomography images. By fitting models to semivariograms, small-scale and large-scale correlation lengths are determined for four samples. Different semivariogram parameters were found for adjacent cores at both resolutions. Relative elementary volume (REV) concepts are related to the stationarity of the sample. A scale disparity factor is defined and is used to determine sample size required for ergodic stationarity with a specified correlation length. This allows for comparison of geostatistical measures and representative elementary volumes. The modifiable areal unit problem is also addressed and used to determine resolution effects on correlation lengths. By changing resolution, a range of correlation lengths can be determined for the same sample. Comparison of voxel volume to the best-fit model correlation length of a single sample at different resolutions reveals a linear scaling effect. Using this relationship, the range of the point value semivariogram is determined. This is the range approached as the voxel size goes to zero. Finally, these results are compared to the regularization theory of point variables for borehole cores and are found to be a better fit for predicting the volume-averaged range.

Current employment status, occupational category, occupational hazard exposure, and job stress in relation to telomere length: The Multiethnic Study of Atherosclerosis (MESA)

PubMed Central

Fujishiro, Kaori; Diez-Roux, Ana V; Landsbergis, Paul; Jenny, Nancy Swords; Seeman, Teresa

2014-01-01

Objective Telomere length has been proposed as a biomarker of cell senescence, which is associated with a wide array of adverse health outcomes. While work is a major determinant of health, few studies have investigated the association of telomere length with various dimensions of occupation. Accelerated cellular aging could be a common pathway linking occupational exposure to several health outcomes. Methods Leukocyte telomere length was assessed using quantitative polymerase chain reaction (Q-PCR) in a community-based sample of 981 individuals (age: 45–84 years old). Questionnaires were used to collect information on current employment status, current or main occupation before retirement, and job strain. The O*NET (Occupational Resource Network) database was linked to the questionnaire data to create 5 exposure measures: physical activity on the job, physical hazard exposure, interpersonal stressors, job control, and job demands. Linear regression was used to estimate associations of occupational characteristics with telomere lengths after adjustment for age, sex, race, socioeconomic position, and several behavioral risk factors. Results There were no mean differences in telomere lengths across current employment status, occupational category, job strain categories or levels of most O*NET exposure measures. There was also no evidence that being in lower status occupational categories or being exposed to higher levels of adverse physical or psychosocial exposures accelerated the association between age and telomere shortening. Conclusions Cellular aging as reflected by shorter telomeres does not appear to be an important pathway linking occupation to various health outcomes. PMID:23686115

Effect of rehabilitation length of stay on outcomes in individuals with traumatic brain injury or spinal cord injury: a systematic review protocol.

PubMed

Lamontagne, Marie-Eve; Gagnon, Cynthia; Allaire, Anne-Sophie; Noreau, Luc

2013-07-20

Rehabilitation interventions are a key component of the services required by individuals with neurotrauma to recover or compensate for altered abilities and achieve optimal social participation. Primary studies have produced evidence of the effect of rehabilitation length of stay on individuals with neurotrauma. However, to date no systematic review of this evidence has been performed. This makes it difficult for managers and clinicians to base their rehabilitation practices upon evidence. Supported by a committee of stakeholders, we will search electronic databases for research articles examining the association between length of stay or intensity of inpatient rehabilitation services and outcomes or the determinants of inpatient rehabilitation length of stay in adults with neurotrauma published after January 1990. Two researchers will independently screen the article titles and abstracts for inclusion. Two reviewers will independently extract the data. Primary outcomes of interest will be level of function, participation and return to work. If the data allow it, a meta-analysis of the studies will be performed. The results of this systematic review will clarify the factors that influence length of stay and intensity of rehabilitation services for individuals with TBI and SCI. They will give clinicians indications for optimal length of stay in these patient populations, contributing to better quality of care and better functional results. This review protocol has been registered on the PROSPERO database (CRD42012003120) and is available at http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42012003120.

Similarity and Scale Invariance of Velocity and Temperature Structure Functions within and above Dense Canopies

NASA Astrophysics Data System (ADS)

Ghannam, K.; Katul, G. G.; Chamecki, M.

2016-12-01

The scale-wise properties of turbulent flow statistics are conventionally quantified using the structure function D_ss (r)= <〖(Δs)〗^2 > describing velocity (s=u) or scalar (s=c) concentration increments Δs=s(x+r)-s(x) at various scales or separation distances r, where <.> is Reynolds averaging over coordinates of statistical homogeneity. For locally homogeneous and isotropic turbulence, the structure function can unfold statistical invariance of the form D_ss (βr)=β^p D_ss (r) as has been demonstrated by Kolmogorov's theory for the inertial subrange in the absence of intermittency corrections. For scales larger than inertial, scale invariance need not hold though universal scaling properties can still emerge provided an appropriate length and velocity scales are identified. One recent study on the structure function of the streamwise velocity (s=u) in smooth and rough wall-bounded flows argued that a logarithmic scaling of the form D_ss/(u_*^2 )=A+B ln(r/l_ɛ ) exists at any height z above the wall (or roughness elements), with,l_ɛ,〖 u〗_*, A and B being a dissipation length scale, the friction velocity, and two similarity constants to be determined. Whether this scaling is valid across all atmospheric stability regimes in the roughness sublayer (RSL) and the possible co-existence of length scales other than l_ɛ that collapse D_ss (r) for velocity and temperature frames the scope of this work. Using year-round field measurements within and above an Amazonian canopy, the work here explores the aforementioned scaling for the streamwise (s=u) and vertical velocity (s=w) components, along with its extension to active scalars (s=T, the air temperature) inside canopies and in the RSL above canopies. While the premise is that a length scale such as l_ɛ may serve as a master closure length scale for turbulent momentum and heat flux budgets, the role of the vorticity thickness, the Obukhov length, the adjustment length scale, and height z are also explored for various scale (or r) regimes. Because the RSL blends D_ss (r) from its form inside the canopy to its form in the well-studied atmospheric surface layer, the scaling laws derived here offer a new perspective on the thickness of the RSL for momentum and scalars and its variations with atmospheric stability.

28 CFR 551.4 - Hair length.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Hair length. 551.4 Section 551.4 Judicial... Hair length. (a) The Warden may not restrict hair length if the inmate keeps it neat and clean. (b) The Warden shall require an inmate with long hair to wear a cap or hair net when working in food service or...

28 CFR 551.4 - Hair length.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Hair length. 551.4 Section 551.4 Judicial... Hair length. (a) The Warden may not restrict hair length if the inmate keeps it neat and clean. (b) The Warden shall require an inmate with long hair to wear a cap or hair net when working in food service or...

28 CFR 551.4 - Hair length.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Hair length. 551.4 Section 551.4 Judicial... Hair length. (a) The Warden may not restrict hair length if the inmate keeps it neat and clean. (b) The Warden shall require an inmate with long hair to wear a cap or hair net when working in food service or...

Intensity of musculoskeletal pain and (in) ability to work in nursing.

PubMed

Magnago, Tânia Solange Bosi de Souza; de Lima, Ana Cláudia Soares; Prochnow, Andrea; Ceron, Marinez Diniz da Silva; Tavares, Juliana Petri; Urbanetto, Janete de Souza

2012-01-01

the aim was to evaluate the association between the intensity of musculoskeletal pain and reduction in work ability among nursing workers. a cross-sectional study, involving 592 nursing staff in a public university hospital in Rio Grande do Sul, Brazil. The Brazilian version of the Finnish questionnaire for calculating Work Ability Index was used, whose score varies from 7 to 49 points. The score was dichotomized as reduced work ability (7 to 36 points) and good/excellent ability (37 to 49 points). The intensity of musculoskeletal pain over the previous week was evaluated, using a numerical pain scale. 43.3% of the participants had reduced work ability and 48.8% reported strong to unbearable pain. Even after adjusting for potentially confounding factors (function and length of service in the function), the workers who mentioned strong to unbearable pain were four times more likely to be classified in the group with reduced work ability. A positive association was determined between intensity of musculoskeletal pain and reduction in work ability. It is necessary to adopt intervention measures in the organizational structure, so as to promote/restore work ability.

Stipe Length as an Indicator of Reproductive Maturity in the Kelp Ecklonia cava

NASA Astrophysics Data System (ADS)

Kim, Sangil; Youn, Suk Hyun; Oh, Hyun-Ju; Choi, Sun Kyeong; Kang, Yun Hee; Kim, Tae-Hoon; Lee, Hyuk Je; Choi, Kwang-Sik; Park, Sang Rul

2018-05-01

We conducted testing to determine whether stipe length is a useful indicator of reproductive maturity in the kelp Ecklonia cava, a species that plays a pivotal role in ecosystem functioning and services in subtidal areas. Approximately 100 sporophytes with stipes of various lengths were collected during the fertile period (July-November, 2013). We investigated the relationships between stipe length and other morphological characteristics to determine whether stipe length could indicate the age of reproductive maturity. Primary blade length, longest blade length, thallus height, and total length showed significant relationships with stipe length. The length of the primary and longest blades gradually declined as stipe length increased above 125 mm. Zoosporangial sori were found on the blades of more than 70% of individuals with stipes longer than 125 mm, but on only 8% of individuals with stipes less than 125 mm long. Stipe length therefore seems to be an acceptable proxy for reproductive maturity. Another factor to consider, however, is that all specimens with zoosporangial sori, regardless of stipe length, had a dry weight of 80 g or more; thus, individual biomass may also be an important parameter influencing the initiation of reproduction.

The effect of maternity leave length and time of return to work on breastfeeding.

PubMed

Ogbuanu, Chinelo; Glover, Saundra; Probst, Janice; Liu, Jihong; Hussey, James

2011-06-01

We investigated the effect of maternity leave length and time of first return to work on breastfeeding. Data were from the Early Childhood Longitudinal Study-Birth Cohort. Restricting our sample to singletons whose biological mothers were the respondents at the 9-month interview and worked in the 12 months before delivery (N = 6150), we classified the length of total maternity leave (weeks) as 1 to 6, 7 to 12, ≥ 13, and did not take; paid maternity leave (weeks) as 0, 1 to 6, ≥ 7, and did not take; and time of return to work postpartum (weeks) as 1 to 6, 7 to 12, ≥ 13, and not yet returned. Analyses included χ(2) tests and multiple logistic regressions. In our study population, 69.4% initiated breastfeeding with positive variation by both total and paid maternity leave length, and time of return to work. In adjusted analyses, neither total nor paid maternity leave length had any impact on breastfeeding initiation or duration. Compared with those returning to work within 1 to 6 weeks, women who had not yet returned to work had a greater odds of initiating breastfeeding (odds ratio [OR]: 1.46 [1.08-1.97]; risk ratios [RR]: 1.13 [1.03-1.22]), continuing any breastfeeding beyond 6 months (OR: 1.41 [0.87-2.27]; RR: 1.25 [0.91-1.61]), and predominant breastfeeding beyond 3 months (OR: 2.01 [1.06-3.80]; RR: 1.70 [1.05-2.53]). Women who returned to work at or after 13 weeks postpartum had higher odds of predominantly breastfeeding beyond 3 months (OR: 2.54 [1.51-4.27]; RR: 1.99 [1.38-2.69]). If new mothers delay their time of return to work, then duration of breastfeeding among US mothers may lengthen.

The Effect of Maternity Leave Length and Time of Return to Work on Breastfeeding

PubMed Central

Glover, Saundra; Probst, Janice; Liu, Jihong; Hussey, James

2011-01-01

OBJECTIVE: We investigated the effect of maternity leave length and time of first return to work on breastfeeding. METHODS: Data were from the Early Childhood Longitudinal Study–Birth Cohort. Restricting our sample to singletons whose biological mothers were the respondents at the 9-month interview and worked in the 12 months before delivery (N = 6150), we classified the length of total maternity leave (weeks) as 1 to 6, 7 to 12, ≥13, and did not take; paid maternity leave (weeks) as 0, 1 to 6, ≥7, and did not take; and time of return to work postpartum (weeks) as 1 to 6, 7 to 12, ≥13, and not yet returned. Analyses included χ2 tests and multiple logistic regressions. RESULTS: In our study population, 69.4% initiated breastfeeding with positive variation by both total and paid maternity leave length, and time of return to work. In adjusted analyses, neither total nor paid maternity leave length had any impact on breastfeeding initiation or duration. Compared with those returning to work within 1 to 6 weeks, women who had not yet returned to work had a greater odds of initiating breastfeeding (odds ratio [OR]: 1.46 [1.08–1.97]; risk ratios [RR]: 1.13 [1.03–1.22]), continuing any breastfeeding beyond 6 months (OR: 1.41 [0.87–2.27]; RR: 1.25 [0.91–1.61]), and predominant breastfeeding beyond 3 months (OR: 2.01 [1.06–3.80]; RR: 1.70 [1.05–2.53]). Women who returned to work at or after 13 weeks postpartum had higher odds of predominantly breastfeeding beyond 3 months (OR: 2.54 [1.51–4.27]; RR: 1.99 [1.38–2.69]). CONCLUSION: If new mothers delay their time of return to work, then duration of breastfeeding among US mothers may lengthen. PMID:21624878

Environmental determinism, and not interspecific competition, drives morphological variability in Australasian warblers (Acanthizidae).

PubMed

García-Navas, Vicente; Rodríguez-Rey, Marta; Marki, Petter Z; Christidis, Les

2018-04-01

Interspecific competition is thought to play a key role in determining the coexistence of closely related species within adaptive radiations. Competition for ecological resources can lead to different outcomes from character displacement to, ultimately, competitive exclusion. Accordingly, divergent natural selection should disfavor those species that are the most similar to their competitor in resource use, thereby increasing morphological disparity. Here, we examined ecomorphological variability within an Australo-Papuan bird radiation, the Acanthizidae, which include both allopatric and sympatric complexes. In addition, we investigated whether morphological similarities between species are related to environmental factors at fine scale (foraging niche) and/or large scale (climate). Contrary to that predicted by the competition hypothesis, we did not find a significant correlation between the morphological similarities found between species and their degree of range overlap. Comparative modeling based on both a priori and data-driven identification of selective regimes suggested that foraging niche is a poor predictor of morphological variability in acanthizids. By contrast, our results indicate that climatic conditions were an important factor in the formation of morphological variation. We found a significant negative correlation between species scores for PC1 (positively associated to tarsus length and tail length) and both temperature and precipitation, whereas PC2 (positively associated to bill length and wing length) correlated positively with precipitation. In addition, we found that species inhabiting the same region are closer to each other in morphospace than to species outside that region regardless of genus to which they belong or its foraging strategy. Our results indicate that the conservative body form of acanthizids is one that can work under a wide variety of environments (an all-purpose morphology), and the observed interspecific similarity is probably driven by the common response to environment.

Evolutionary potential of the extrinsic incubation period of dengue virus in Aedes aegypti.

PubMed

Ye, Yixin H; Chenoweth, Stephen F; Carrasco, Alison M; Allen, Scott L; Frentiu, Francesca D; van den Hurk, Andrew F; Beebe, Nigel W; McGraw, Elizabeth A

2016-11-01

Dengue fever is the most common arboviral disease worldwide. It is caused by dengue viruses (DENV) and the mosquito Aedes aegypti is its primary vector. One of the most powerful determinants of a mosquito's ability to transmit DENV is the length of the extrinsic incubation period (EIP), the time it takes for a virus to be transmitted by a mosquito after consuming an infected blood meal. Here, we repeatedly measured DENV load in the saliva of individual mosquitoes over their lifetime and used this in combination with a breeding design to determine the extent to which EIP might respond to the evolutionary forces of drift and selection. We demonstrated that genetic variation among mosquitoes contributes significantly to transmission potential and length of EIP. We reveal that shorter EIP is genetically correlated with reduced mosquito lifespan, highlighting negative life-history consequences for virus-infected mosquitoes. This work highlights the capacity for local genetic variation in mosquito populations to evolve and to dramatically affect the nature of human outbreaks. It also provides the impetus for isolating mosquito genes that determine EIP. More broadly, our dual experimental approach offers new opportunities for studying the evolutionary potential of transmission traits in other vector/pathogen systems. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

Derivation and application of a mathematical model for long bone growth.

PubMed

Seetharam, Suneil; Bhatia, Sujata K

2012-01-01

The objective of this work was to develop a mathematical model of long bone growth and to gain insights regarding growth disorders. A cell balance (mass balance of moving cells) assessment was performed on the three regions of the growth plate, to determine the variables (including number of proliferating cells, and division rate of proliferating cells) that influence tibia growth rate. Once this relationship was established, clinical data were used to understand how tibia growth rate and number of proliferating cells change with time. These equations were then inserted into the model to determine how cell division rate changes with time. The model was utilized to determine the influence of growth time, and to measure changes in vitamin C deficiency, Indian hedgehog (IHH) expression, and bone morphogenetic protein-2 (BMP-2) implants on tibia length. According to the model, a 10-month discrepancy in growth time between the two tibias is required to produce clinically significant leg asymmetry. In addition, vitamin C deficiency, IHH overexpression, and BMP-2 implants can all affect tibia length. These bioactive molecules have the greatest effect on tibia growth rate when these perturbations occur early in life for extended periods of time. The results are significant for modeling and predicting the effects of perturbations, including bioactive implants, on long bone growth.

Complex families, the social determinants of health and psychosocial interventions: Deconstruction of a day in the life of hospital social workers.

PubMed

Muskat, Barbara; Craig, Shelley L; Mathai, Biju

2017-09-01

The roles of hospital social workers are delineated in the literature; however, their daily interventions have only been described anecdotally. This study analyzes the daily work of social workers in a pediatric hospital through a survey completed which examined factors related to interventions utilized and time spent per case over a 1-day period. Length and types of interventions were associated with the social determinants of health, time since diagnosis, biopsychosocial issues, and perception of complexity. The study offers a snapshot of the personalized expertise, provided by social workers that addresses complex contextual and biopsychosocial concerns of patient and families.

Design of open rectangular and trapezoidal channels

NASA Astrophysics Data System (ADS)

González, C. P.; Vera, P. E.; Carrillo, G.; García, S.

2018-04-01

In this work, the results of designing open channels in rectangular and trapezoidal form are presented. For the development of the same important aspects were taken as determination of flows by means of formula of the rational method, area of the surface for its implementation, optimal form of the flow to meet the needs of that environment. In the design the parameter of the hydraulic radius expressed in terms of the hydraulic area and wet perimeter was determined, considering that the surface on which the fluid flows is the product of the perimeter of the section and the length of the channel and where shear is generated by the condition of no slippage.

Lifestyle changes of Japanese people on overseas assignment in Michigan, USA.

PubMed

Kitamura, Kazuya; Fetters, Michael D; Sano, Kiyoshi; Sato, Juichi; Ban, Nobutaro

2009-07-16

Temporary work assignments in the United States (US) are widely considered to have negative health outcomes on Asians mostly due to adverse changes in diet and exercise, though there is little research on this phenomenon. This study investigated the impact of lifestyle changes on the biological and psychological health and health behaviours of Japanese people on temporary assignments in the US. In this cross sectional survey, we distributed a 38 item self-administered questionnaire addressing health habits, mental health function, lifestyle changes and dietary habits to adult Japanese patients presenting for general physicals at a family medicine clinic serving Japanese patients. We conducted simple statistics and regression analysis between length of stay and other health outcomes to determine whether length of residence in the US was predictive of negative lifestyle changes. Most participants reported increased caloric intake, weight gain, and less exercise. They also reported increased time with family. More women than men reported physical symptoms and anxiety related to stress. Smoking and alcohol intake were essentially unchanged. No associations were identified between length of residence in the US and health lifestyle habits or other health outcomes. Negative lifestyle changes occur in diet and exercise for overseas Japanese people, but a positive change in increased family time was found. Women appear to be at a greater risk for somatic disorders than men. As duration of stay does not appear predictive of adverse changes, clinicians should advise patients going abroad of these risks regardless of the term of the work assignment.

Diversity in the association between occupation and lung cancer among black and white men.

PubMed

Swanson, G M; Lin, C S; Burns, P B

1993-01-01

A population-based case comparison study of incident lung cancer and occupational risk factors was conducted in the tricounty Detroit metropolitan area. Nearly 6000 lung cancer cases and a comparison group of 3600 colon cancer cases were interviewed. This report includes 3792 white and black male lung cancer cases and 1966 black and white colon cancer referents. Cigarette smoking, age at diagnosis, and lifetime work history were assessed to determine the relationship between length of employment in specific occupations and industries and lung cancer. Diverse patterns of association between work history and lung cancer were observed for black and white men. Significant associations were seen between lung cancer and increasing length of employment in the following occupations: for white men, concrete and terrazzo finishers, grinding machine operators, heat treating machine operators, miscellaneous machine operators, truck drivers, driver sales, and laborers; for black men, farm workers, automobile mechanics, painting machine operators, furnace operators, and garbage collectors; for both black and white men, farmers, slicing and cutting machine operators, and garbage collectors. Distinct patterns for black and white men also were observed for length of employment by industry. This study clearly demonstrates the need to include black men in studies of occupational cancer etiology and to evaluate black and white men separately. It also indicates the necessity for cigarette smoking history to accurately assess workplace cancer risks. We propose guidelines for incorporating the use of biomarkers into further studies of occupational cancer epidemiology.

Hand anthropometry of Indian women.

PubMed

Nag, Anjali; Nag, P K; Desai, Hina

2003-06-01

Data on the physical dimension of the hand of Indian women are scanty. This information is necessary to ascertain human-machine compatibility in the design of manual systems for the bare and gloved hand, such as design and sizing of hand tools, controls, knobs and other applications in different kinds of precision and power grips. The present study was undertaken to generate hand anthropometric data of 95 women, working in informal industries (beedi, agarbatti and garment making). Fifty one hand measurements of the right hand (lengths, breadths, circumferences, depths, spreads and clearances of hand and fingers) were taken, using anthropometric sliding and spreading calipers, measuring tape and handgrip strength dynamometer. The data were statistically analyzed to determine the normality of data and the percentile values of different hand dimensions, and simple and multiple regression analysis were done to determine better predictors of hand length and grip strength. The hand breadths, circumferences and depths were approximately normally distributed, with some deviation in case of the finger lengths. Hand length was significantly correlated with the fist, wrist and finger circumferences. The fist and wrist circumferences, in combination, were better predictors of hand length. The hand lengths, breadths and depths, including finger joints of the Indian women studied were smaller than those of American, British and West Indian women. The hand circumferences of the Indian women were also smaller than the American women. Grip strengths of Indian women (20.36 +/- 3.24 kg) were less than those of American, British and West Indian women. Grip strength was found to be statistically significant with hand dimensions, such as hand height perpendicular to wrist crease (digit 5), proximal interphalangeal joint breadth (digit 3) and hand spread across wedge 1. The women who are forced to frequently use cutters, strippers and other tools, which are not optimally designed to their hand dimensions and strength range, might have higher prevalence of clinical symptoms and disorders of the hand. In view of the human hand-tool interface requirements, the present data on Indian women would be useful for ergo-design applications of hand tools and devices.

Monitoring start of season in Alaska with GLOBE, AVHRR, and MODIS data

NASA Astrophysics Data System (ADS)

Robin, Jessica; Dubayah, Ralph; Sparrow, Elena; Levine, Elissa

2008-03-01

This work evaluates whether continuity between Advanced Very High Resolution Radiometer (AVHRR) and Moderate Resolution Imaging Spectroradiometer (MODIS) normalized difference vegetation index (NDVI) is achievable for monitoring phenological changes in Alaska. This work also evaluates whether NDVI can detect changes in start of the growing season (SOS) in this region. Six quadratic regression models with NDVI as a function of accumulated growing degree days (AGDD) were developed from 2001 through 2004 AVHRR and MODIS NDVI data sets for urban, mixed, and forested land covers. Model parameters determined NDVI values for start of the observational period as well as peak and length of the growing season. NDVI values for start of the growing season were determined from the model equations and field observations of SOS made by GLOBE students and researchers at University of Alaska Fairbanks. AGDD was computed from daily air temperature. AVHRR and MODIS models were significantly different from one another with differences in the start of the observational season as well as start, peak, and length of the growing season. Furthermore, AGDD for SOS was significantly lower during the 1990s than the 1980s. NDVI values at SOS did not detect this change. There are limitations with using NDVI to monitor phenological changes in these regions because of snow, the large extent of conifers, and clouds, which restrict the composite period. In addition, differing processing and spectral characteristics restrict continuity between AVHRR and MODIS NDVI data sets.

Objective assessment based on motion-related metrics and technical performance in laparoscopic suturing.

PubMed

Sánchez-Margallo, Juan A; Sánchez-Margallo, Francisco M; Oropesa, Ignacio; Enciso, Silvia; Gómez, Enrique J

2017-02-01

The aim of this study is to present the construct and concurrent validity of a motion-tracking method of laparoscopic instruments based on an optical pose tracker and determine its feasibility as an objective assessment tool of psychomotor skills during laparoscopic suturing. A group of novice ([Formula: see text] laparoscopic procedures), intermediate (11-100 laparoscopic procedures) and experienced ([Formula: see text] laparoscopic procedures) surgeons performed three intracorporeal sutures on an ex vivo porcine stomach. Motion analysis metrics were recorded using the proposed tracking method, which employs an optical pose tracker to determine the laparoscopic instruments' position. Construct validation was measured for all 10 metrics across the three groups and between pairs of groups. Concurrent validation was measured against a previously validated suturing checklist. Checklists were completed by two independent surgeons over blinded video recordings of the task. Eighteen novices, 15 intermediates and 11 experienced surgeons took part in this study. Execution time and path length travelled by the laparoscopic dissector presented construct validity. Experienced surgeons required significantly less time ([Formula: see text]), travelled less distance using both laparoscopic instruments ([Formula: see text]) and made more efficient use of the work space ([Formula: see text]) compared with novice and intermediate surgeons. Concurrent validation showed strong correlation between both the execution time and path length and the checklist score ([Formula: see text] and [Formula: see text], [Formula: see text]). The suturing performance was successfully assessed by the motion analysis method. Construct and concurrent validity of the motion-based assessment method has been demonstrated for the execution time and path length metrics. This study demonstrates the efficacy of the presented method for objective evaluation of psychomotor skills in laparoscopic suturing. However, this method does not take into account the quality of the suture. Thus, future works will focus on developing new methods combining motion analysis and qualitative outcome evaluation to provide a complete performance assessment to trainees.

Length-dependent structural stability of linear monatomic Cu wires

NASA Astrophysics Data System (ADS)

Singh, Gurvinder; Kumar, Krishan; Singh, Baljinder; Moudgil, R. K.

2018-05-01

We present first-principle calculations based on density functional theory for the finite-length monatomic Cu atom linear wires. The structure and its stability with increasing wire length in terms of number of atoms (N) is determined. Interestingly, the bond length is found to exhibit an oscillatory structure (the so-called magic length phenomenon), with a qualitative change in oscillatory behavior as one moves from even N wire to odd N wire. The even N wires follow simple even-odd oscillations whereas odd N wires show a phase change at the half length of the wires. The stability of the wire structure, determined in terms of the wire formation energy, also contains even-odd oscillation as a function of wire length. However, the oscillations in formation energy reverse its phase after the wire length is increased beyond N=12. Our findings are seen to be qualitatively consistent with recent simulations for a similar class finite-length metal atom wires.

Length-dependent transport in molecular junctions based on SAMs of alkanethiols and alkanedithiols: effect of metal work function and applied bias on tunneling efficiency and contact resistance.

PubMed

Engelkes, Vincent B; Beebe, Jeremy M; Frisbie, C Daniel

2004-11-03

Nanoscopic tunnel junctions were formed by contacting Au-, Pt-, or Ag-coated atomic force microscopy (AFM) tips to self-assembled monolayers (SAMs) of alkanethiol or alkanedithiol molecules on polycrystalline Au, Pt, or Ag substrates. Current-voltage traces exhibited sigmoidal behavior and an exponential attenuation with molecular length, characteristic of nonresonant tunneling. The length-dependent decay parameter, beta, was found to be approximately 1.1 per carbon atom (C(-1)) or 0.88 A(-)(1) and was independent of applied bias (over a voltage range of +/-1.5 V) and electrode work function. In contrast, the contact resistance, R(0), extrapolated from resistance versus molecular length plots showed a notable decrease with both applied bias and increasing electrode work function. The doubly bound alkanedithiol junctions were observed to have a contact resistance approximately 1 to 2 orders of magnitude lower than the singly bound alkanethiol junctions. However, both alkanethiol and dithiol junctions exhibited the same length dependence (beta value). The resistance versus length data were also used to calculate transmission values for each type of contact (e.g., Au-S-C, Au/CH(3), etc.) and the transmission per C-C bond (T(C)(-)()(C)).

Gait as solution, but what is the problem? Exploring cost, economy and compromise in locomotion.

PubMed

Bertram, John E A

2013-12-01

Many studies have examined how legged mammals move, defining 'what' happens in locomotion. However, few ask 'why' those motions occur as they do. The energetic and functional constraints acting on an animal require that locomotion should be metabolically 'cost effective' and this in large part determines the strategies available to accomplish the task. Understanding the gaits utilised, within the spectrum of gaits possible, and determination of the value of specific relationships among speed, stride length, stride frequency and morphology, depends on identifying the fundamental costs involved and the effects of different movement strategies on those costs. It is argued here that a fundamental loss associated with moving on limbs (centre of mass momentum and energy loss) and two costs involved with controlling and replacing that loss (muscular work of the supporting limb during stance and muscular work of repositioning the limbs during swing) interact to determine the cost trade-offs involved and the optimisation strategies available for each species and speed. These optimisation strategies are what has been observed and characterised as gait. Copyright © 2013 Elsevier Ltd. All rights reserved.

30 CFR 1206.111 - How do I determine a transportation allowance if I do not have an arm's-length transportation...

Code of Federal Regulations, 2014 CFR

2014-07-01

... if I do not have an arm's-length transportation contract or arm's-length tariff? 1206.111 Section... I do not have an arm's-length transportation contract or arm's-length tariff? (a) This section applies if you or your affiliate do not have an arm's-length transportation contract, including situations...

30 CFR 1206.111 - How do I determine a transportation allowance if I do not have an arm's-length transportation...

Code of Federal Regulations, 2012 CFR

2012-07-01

... if I do not have an arm's-length transportation contract or arm's-length tariff? 1206.111 Section... I do not have an arm's-length transportation contract or arm's-length tariff? (a) This section applies if you or your affiliate do not have an arm's-length transportation contract, including situations...

30 CFR 1206.111 - How do I determine a transportation allowance if I do not have an arm's-length transportation...

Code of Federal Regulations, 2013 CFR

2013-07-01

... if I do not have an arm's-length transportation contract or arm's-length tariff? 1206.111 Section... I do not have an arm's-length transportation contract or arm's-length tariff? (a) This section applies if you or your affiliate do not have an arm's-length transportation contract, including situations...

30 CFR 1206.111 - How do I determine a transportation allowance if I do not have an arm's-length transportation...

Code of Federal Regulations, 2011 CFR

2011-07-01

... if I do not have an arm's-length transportation contract or arm's-length tariff? 1206.111 Section... transportation allowance if I do not have an arm's-length transportation contract or arm's-length tariff? (a) This section applies if you or your affiliate do not have an arm's-length transportation contract...

Establishment of a Method to Measure Length of the Ulnar Nerve and Standardize F-wave Values in Clinically Normal Beagles

PubMed Central

HIRASAWA, Shun; SHIMIZU, Miki; MARUI, Yuumi; KISHIMOTO, Miori; OKUNO, Seiichi

2014-01-01

We designed a new method of measuring the length of the ulnar nerve and determining standard values for F-wave parameters of the ulnar nerve in clinically normal beagles. Nerve length must be precisely measured to determine F-wave latency and conduction velocity. The length of the forelimb has served as the length of the ulnar nerve for F-wave assessments, but report indicates that F-wave latency is proportional to the length of the pathway traveled by nerve impulses. Therefore, we measured the surface distance from a stimulus point to the spinous process of the first thoracic vertebra (nerve length 1) and the anterior horn of the scapula (nerve length 2) as landmarks through the olecranon and the shoulder blade acromion. The correlation coefficients between the shortest F-wave latency and the length of nerves 1, 2 or the forelimb were 0.61, 0.7 and 0.58. Nerve length 2 generated the highest value. Furthermore, the anterior horn of the scapula was easily palpated in any dog regardless of well-fed body. We concluded that nerve length 2 was optimal for measuring the length of the ulnar nerve. PMID:25649942

Electronegativity effects and single covalent bond lengths of molecules in the gas phase.

PubMed

Lang, Peter F; Smith, Barry C

2014-06-07

This paper discusses in detail the calculation of internuclear distances of heteronuclear single bond covalent molecules in the gaseous state. It reviews briefly the effect of electronegativity in covalent bond length. A set of single bond covalent radii and electronegativity values are proposed. Covalent bond lengths calculated by an adapted form of a simple expression (which calculated internuclear separation of different Group 1 and Group 2 crystalline salts to a remarkable degree of accuracy) show very good agreement with observed values. A small number of bond lengths with double bonds as well as bond lengths in the crystalline state are calculated using the same expression and when compared with observed values also give good agreement. This work shows that covalent radii are not additive and that radii in the crystalline state are different from those in the gaseous state. The results also show that electronegativity is a major influence on covalent bond lengths and the set of electronegativity scale and covalent radii proposed in this work can be used to calculate covalent bond lengths in different environments that have not yet been experimentally measured.

Length distributions of nanowires: Effects of surface diffusion versus nucleation delay

NASA Astrophysics Data System (ADS)

Dubrovskii, Vladimir G.

2017-04-01

It is often thought that the ensembles of semiconductor nanowires are uniform in length due to the initial organization of the growth seeds such as lithographically defined droplets or holes in the substrate. However, several recent works have already demonstrated that most nanowire length distributions are broader than Poissonian. Herein, we consider theoretically the length distributions of non-interacting nanowires that grow by the material collection from the entire length of their sidewalls and with a delay of nucleation of the very first nanowire monolayer. The obtained analytic length distribution is controlled by two parameters that describe the strength of surface diffusion and the nanowire nucleation rate. We show how the distribution changes from the symmetrical Polya shape without the nucleation delay to a much broader and asymmetrical one for longer delays. In the continuum limit (for tall enough nanowires), the length distribution is given by a power law times an incomplete gamma-function. We discuss interesting scaling properties of this solution and give a recipe for analyzing and tailoring the experimental length histograms of nanowires which should work for a wide range of material systems and growth conditions.

Investigation of scale effects in the TRF determined by VLBI

NASA Astrophysics Data System (ADS)

Wahl, Daniel; Heinkelmann, Robert; Schuh, Harald

2017-04-01

The improvement of the International Terrestrial Reference Frame (ITRF) is of great significance for Earth sciences and one of the major tasks in geodesy. The translation, rotation and the scale-factor, as well as their linear rates, are solved in a 14-parameter transformation between individual frames of each space geodetic technique and the combined frame. In ITRF2008, as well as in the current release ITRF2014, the scale-factor is provided by Very Long Baseline Interferometry (VLBI) and Satellite Laser Ranging (SLR) in equal shares. Since VLBI measures extremely precise group delays that are transformed to baseline lengths by the velocity of light, a natural constant, VLBI is the most suitable method for providing the scale. The aim of the current work is to identify possible shortcomings in the VLBI scale contribution to ITRF2008. For developing recommendations for an enhanced estimation, scale effects in the Terrestrial Reference Frame (TRF) determined with VLBI are considered in detail and compared to ITRF2008. In contrast to station coordinates, where the scale is defined by a geocentric position vector, pointing from the origin of the reference frame to the station, baselines are not related to the origin. They are describing the absolute scale independently from the datum. The more accurate a baseline length, and consequently the scale, is estimated by VLBI, the better the scale contribution to the ITRF. Considering time series of baseline length between different stations, a non-linear periodic signal can clearly be recognized, caused by seasonal effects at observation sites. Modeling these seasonal effects and subtracting them from the original data enhances the repeatability of single baselines significantly. Other effects influencing the scale strongly, are jumps in the time series of baseline length, mainly evoked by major earthquakes. Co- and post-seismic effects can be identified in the data, having a non-linear character likewise. Modeling the non-linear motion or completely excluding affected stations is another important step for an improved scale determination. In addition to the investigation of single baseline repeatabilities also the spatial transformation, which is performed for determining parameters of the ITRF2008, are considered. Since the reliability of the resulting transformation parameters is higher the more identical points are used in the transformation, an approach where all possible stations are used as control points is comprehensible. Experiments that examine the scale-factor and its spatial behavior between control points in ITRF2008 and coordinates determined by VLBI only showed that the network geometry has a large influence on the outcome as well. Introducing an unequally distributed network for the datum configuration, the correlations between translation parameters and the scale-factor can become remarkably high. Only a homogeneous spatial distribution of participating stations yields a maximally uncorrelated scale-factor that can be interpreted independent from other parameters. In the current release of the ITRF, the ITRF2014, for the first time, non-linear effects in the time series of station coordinates are taken into account. The present work shows the importance and the right direction of the modification of the ITRF calculation. But also further improvements were found which lead to an enhanced scale determination.

Revisiting the anatomy and biomechanics of the anconeus muscle and its role in elbow stability.

PubMed

Pereira, Barry P

2013-07-01

Recent studies have designated the anconeus muscle as an option for use as a pedicled flap for covering soft tissue defects about the elbow, with reported minimal risk of morbidity. This has raised the question as to the importance of the anconeus muscle and as to whether this is truly an accessory muscle that can be sacrificed, or whether the anconeus muscle significantly contributes to elbow and forearm stability? This study revisits the anatomy and biomechanics of the anconeus muscle and aims to investigate the neuromuscular compartments of the anconeus muscle and to determine the changes in the muscle length, fibre length and moment arm over a range of elbow flexion angles for each compartment. An anatomical study on 8 human cadavers (51-77 years of age) was done and a 2-dimensional kinematic elbow model developed to determine changes in the muscle length and moment arm of the muscle related to changes in elbow flexion angles. The muscle was modelled with two possible lines of action, one along the posterior and another on the anterior edge of the muscle as they had different muscle fibre lengths (posterior: average of 32 mm, anterior: average of 20 mm). The anterior edge also had an aponeurosis which was 70% of its length. From 0 to 120° elbow flexion, the length of the posterior and anterior edges increased with a maximum change recorded at 90° elbow flexion (31.7±1.0 mm and 65.3±1.4 mm, respectively). The moment arm is 14-mm at 0° flexion, but between the posterior and anterior edges it decreases at different rates with increasing elbow flexion angle. Beyond 80°, the anterior edge behaves as an elbow flexor, while the posterior edge remains an elbow extensor. The study demonstrates that the anconeus muscle has two neuromuscular compartments each with distinct intramuscular innervations and muscle fibre lengths. The posterior and deep aspect of the muscle functions as an elbow extensor decreasing in influence with increasing elbow flexion angle. The anterior superficial aspect which is adjacent and parallel to the lateral collateral ligaments, would most likely work in unison to provide constraint to the posterolateral stability of the elbow. Copyright © 2012. Published by Elsevier GmbH.

Population Dynamics of Viral Inactivation

NASA Astrophysics Data System (ADS)

Freeman, Krista; Li, Dong; Behrens, Manja; Streletzky, Kiril; Olsson, Ulf; Evilevitch, Alex

We have investigated the population dynamics of viral inactivation in vitrousing time-resolved cryo electron microscopy combined with light and X-ray scattering techniques. Using bacteriophage λ as a model system for pressurized double-stranded DNA viruses, we found that virions incubated with their cell receptor eject their genome in a stochastic triggering process. The triggering of DNA ejection occurs in a non synchronized manner after the receptor addition, resulting in an exponential decay of the number of genome-filled viruses with time. We have explored the characteristic time constant of this triggering process at different temperatures, salt conditions, and packaged genome lengths. Furthermore, using the temperature dependence we determined an activation energy for DNA ejections. The dependences of the time constant and activation energy on internal DNA pressure, affected by salt conditions and encapsidated genome length, suggest that the triggering process is directly dependent on the conformational state of the encapsidated DNA. The results of this work provide insight into how the in vivo kinetics of the spread of viral infection are influenced by intra- and extra cellular environmental conditions. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE-1252522.

Endodontic Procedural Errors: Frequency, Type of Error, and the Most Frequently Treated Tooth.

PubMed

Yousuf, Waqas; Khan, Moiz; Mehdi, Hasan

2015-01-01

Introduction. The aim of this study is to determine the most common endodontically treated tooth and the most common error produced during treatment and to note the association of particular errors with particular teeth. Material and Methods. Periapical radiographs were taken of all the included teeth and were stored and assessed using DIGORA Optime. Teeth in each group were evaluated for presence or absence of procedural errors (i.e., overfill, underfill, ledge formation, perforations, apical transportation, and/or instrument separation) and the most frequent tooth to undergo endodontic treatment was also noted. Results. A total of 1748 root canal treated teeth were assessed, out of which 574 (32.8%) contained a procedural error. Out of these 397 (22.7%) were overfilled, 155 (8.9%) were underfilled, 16 (0.9%) had instrument separation, and 7 (0.4%) had apical transportation. The most frequently treated tooth was right permanent mandibular first molar (11.3%). The least commonly treated teeth were the permanent mandibular third molars (0.1%). Conclusion. Practitioners should show greater care to maintain accuracy of the working length throughout the procedure, as errors in length accounted for the vast majority of errors and special care should be taken when working on molars.

A new assay based on terminal restriction fragment length polymorphism of homocitrate synthase gene fragments for Candida species identification.

PubMed

Szemiako, Kasjan; Śledzińska, Anna; Krawczyk, Beata

2017-08-01

Candida sp. have been responsible for an increasing number of infections, especially in patients with immunodeficiency. Species-specific differentiation of Candida sp. is difficult in routine diagnosis. This identification can have a highly significant association in therapy and prophylaxis. This work has shown a new application of the terminal restriction fragment length polymorphism (t-RFLP) method in the molecular identification of six species of Candida, which are the most common causes of fungal infections. Specific for fungi homocitrate synthase gene was chosen as a molecular target for amplification. The use of three restriction enzymes, DraI, RsaI, and BglII, for amplicon digestion can generate species-specific fluorescence labeled DNA fragment profiles, which can be used to determine the diagnostic algorithm. The designed method can be a cost-efficient high-throughput molecular technique for the identification of six clinically important Candida species.

A numerical model for charge transport and energy conversion of perovskite solar cells.

PubMed

Zhou, Yecheng; Gray-Weale, Angus

2016-02-14

Based on the continuity equations and Poisson's equation, we developed a numerical model for perovskite solar cells. Due to different working mechanisms, the model for perovskite solar cells differs from that of silicon solar cells and Dye Sensitized Solar Cells. The output voltage and current are calculated differently, and in a manner suited in particular to perovskite organohalides. We report a test of our equations against experiment with good agreement. Using this numerical model, it was found that performances of solar cells increase with charge carrier's lifetimes, mobilities and diffusion lengths. The open circuit voltage (Voc) of a solar cell is dependent on light intensities, and charge carrier lifetimes. Diffusion length and light intensity determine the saturated current (Jsc). Additionally, three possible guidelines for the design and fabrication of perovskite solar cells are suggested by our calculations. Lastly, we argue that concentrator perovskite solar cells are promising.

Length of day-care attendance and attachment behavior in eighteen-month-old infants.

PubMed

Schwartz, P

1983-08-01

Differences in the attachment behavior of 18-month-old full-time, part-time, and non-day-care infants from intact middle-class homes were compared. Mothers of the day-care infants had made arrangements to return to work before their infants' birth, and all the infants had been placed in day-care homes before 9 months of age. The study involved 2 sessions: a home observation and the strange-situation procedure in a laboratory setting. The home-observation and rating scale scores of maternal behaviors directed at the child yielded few group differences. More full-time day-care children (but not part-time children) were found to display avoidance of the mother during the final reunion episode of the strange-situation procedure than did non-day-care children. The length of the daily separation appears to be an important determinant of day-care effects on infant-mother attachment.

Delocalization of Coherent Triplet Excitons in Linear Rigid Rod Conjugated Oligomers.

PubMed

Hintze, Christian; Korf, Patrick; Degen, Frank; Schütze, Friederike; Mecking, Stefan; Steiner, Ulrich E; Drescher, Malte

2017-02-02

In this work, the triplet state delocalization in a series of monodisperse oligo(p-phenyleneethynylene)s (OPEs) is studied by pulsed electron paramagnetic resonance (EPR) and pulsed electron nuclear double resonance (ENDOR) determining zero-field splitting, optical spin polarization, and proton hyperfine couplings. Neither the zero-field splitting parameters nor the optical spin polarization change significantly with OPE chain length, in contrast to the hyperfine coupling constants, which showed a systematic decrease with chain length n according to a 2/(1 + n) decay law. The results provide striking evidence for the Frenkel-type nature of the triplet excitons exhibiting full coherent delocalization in the OPEs under investigation with up to five OPE repeat units and with a spin density distribution described by a nodeless particle in the box wave function. The same model is successfully applied to recently published data on π-conjugated porphyrin oligomers.

Thermodynamic properties of small aggregates of rare-gas atoms

NASA Technical Reports Server (NTRS)

Etters, R. D.; Kaelberer, J.

1975-01-01

The present work reports on the equilibrium thermodynamic properties of small clusters of xenon, krypton, and argon atoms, determined from a biased random-walk Monte Carlo procedure. Cluster sizes ranged from 3 to 13 atoms. Each cluster was found to have an abrupt liquid-gas phase transition at a temperature much less than for the bulk material. An abrupt solid-liquid transition is observed for thirteen- and eleven-particle clusters. For cluster sizes smaller than 11, a gradual transition from solid to liquid occurred over a fairly broad range of temperatures. Distribution of number of bond lengths as a function of bond length was calculated for several systems at various temperatures. The effects of box boundary conditions are discussed. Results show the importance of a correct description of boundary conditions. A surprising result is the slow rate at which system properties approach bulk behavior as cluster size is increased.

Ion acceleration in electrostatic collisionless shock: on the optimal density profile for quasi-monoenergetic beams

NASA Astrophysics Data System (ADS)

Boella, E.; Fiúza, F.; Stockem Novo, A.; Fonseca, R.; Silva, L. O.

2018-03-01

A numerical study on ion acceleration in electrostatic shock waves is presented, with the aim of determining the best plasma configuration to achieve quasi-monoenergetic ion beams in laser-driven systems. It was recently shown that tailored near-critical density plasmas characterized by a long-scale decreasing rear density profile lead to beams with low energy spread (Fiúza et al 2012 Phys. Rev. Lett. 109 215001). In this work, a detailed parameter scan investigating different plasma scale lengths is carried out. As result, the optimal plasma spatial scale length that allows for minimizing the energy spread while ensuring a significant reflection of ions by the shock is identified. Furthermore, a new configuration where the required profile has been obtained by coupling micro layers of different densities is proposed. Results show that this new engineered approach is a valid alternative, guaranteeing a low energy spread with a higher level of controllability.

Cross-sectional examination of the association between shift length and hospital nurses job satisfaction and nurse reported quality measures.

PubMed

Ball, Jane; Day, Tina; Murrells, Trevor; Dall'Ora, Chiara; Rafferty, Anne Marie; Griffiths, Peter; Maben, Jill

2017-01-01

Twenty-four hour nursing care involves shift work including 12-h shifts. England is unusual in deploying a mix of shift patterns. International evidence on the effects of such shifts is growing. A secondary analysis of data collected in England exploring outcomes with 12-h shifts examined the association between shift length, job satisfaction, scheduling flexibility, care quality, patient safety, and care left undone. Data were collected from a questionnaire survey of nurses in a sample of English hospitals, conducted as part of the RN4CAST study, an EU 7 th Framework funded study. The sample comprised 31 NHS acute hospital Trusts from 401 wards, in 46 acute hospital sites. Descriptive analysis included frequencies, percentages and mean scores by shift length, working beyond contracted hours and day or night shift. Multi-level regression models established statistical associations between shift length and nurse self-reported measures. Seventy-four percent (1898) of nurses worked a day shift and 26% (670) a night shift. Most Trusts had a mixture of shifts lengths. Self-reported quality of care was higher amongst nurses working ≤8 h (15.9%) compared to those working longer hours (20.0 to 21.1%). The odds of poor quality care were 1.64 times higher for nurses working ≥12 h (OR = 1.64, 95% CI 1.18-2.28, p  = 0.003). Mean 'care left undone' scores varied by shift length: 3.85 (≤8 h), 3.72 (8.01-10.00 h), 3.80 (10.01-11.99 h) and were highest amongst those working ≥12 h (4.23) ( p  < 0.001). The rate of care left undone was 1.13 times higher for nurses working ≥12 h (RR = 1.13, 95% CI 1.06-1.20, p  < 0.001). Job dissatisfaction was higher the longer the shift length: 42.9% (≥12 h (OR = 1.51, 95% CI 1.17-1.95, p  = .001); 35.1% (≤8 h) 45.0% (8.01-10.00 h), 39.5% (10.01-11.99 h). Our findings add to the growing international body of evidence reporting that ≥12 shifts are associated with poor ratings of quality of care and higher rates of care left undone. Future research should focus on how 12-h shifts can be optimised to minimise potential risks.

In vitro comparison in a manikin model: increasing apical enlargement with K3 and K3XF rotary instruments.

PubMed

Olivieri, Juan Gonzalo; Stöber, Eva; García Font, Marc; González, Jose Antonio; Bragado, Pablo; Roig, Miguel; Duran-Sindreu, Fernando

2014-09-01

The aim of the study was to compare the K3 and K3XF systems (SybronEndo, Glendora, CA) after 1 and 2 uses by evaluating apical transportation, working length loss, and working time in a manikin model. Mesial canals of 40 extracted first mandibular molars were instrumented. Radiographs taken after instrumentation with #25, #30, #35, and #40 files were superimposed on the preoperative image in both mesiodistal and buccolingual angulations. AutoCAD (Autodesk Inc, San Rafael, CA) was used to measure working length loss and apical transportation at 0, 0.5, and 1 mm from the working length (WL). The working time was measured. Group comparison was analyzed using post hoc Tukey honestly significant difference tests (P < .05). No significant differences were found in apical transportation, working length loss between K3 and K3XF systems, or between the number of uses. Significant differences were found when canal enlargement was performed to a #35-40 (P < .05). K3 instrumentation performed significantly faster (29.6 ± 15.4) than with the K3XF system (40.2 ± 17.7) (P < .05). No differences were observed in working time when comparing the number of uses. K3 and R-phase K3XF rotary systems shaped curved root canals safely with minimal apical transportation, even up to a 40/04 file. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Effect of customization of master gutta-percha cone on apical control of root filling using different techniques: an ex vivo study.

PubMed

van Zyl, S P; Gulabivala, K; Ng, Y-L

2005-09-01

(i) To compare the prevalence of extrusion of root filling material when placed using different root filling techniques, with or without customization of the master gutta-percha (GP) cone; and (ii) to investigate the effects of some factors influencing root filling extrusion and presence of voids. A total of 180 roots were selected, prepared and randomly allocated to three groups. Five general dental practitioners performed the root fillings; each filled one group of roots (n = 60) using each of three techniques; 'cold lateral compaction' (n = 20), 'warm vertical compaction' (n = 20) and 'continuous-wave' (n = 20) techniques. For each obturation technique, the master GP cone was customized using chloroform in 10 samples. Two groups of the roots were recycled to allow all five operators to fulfill their remit. Two observers, blind to operator and obturation technique, examined the radiographs (master apical file, post-obturation) to determine the presence of root filling extrusion and voids within the apical 5 mm, independently. Root filling extrusion was also confirmed by direct inspection of the root apex after obturation. The data were analysed using logistic regression models. A total of 300 root fillings were performed; nine were excluded from the analysis. Most of the root fillings (80%, n = 233) were placed within 0.5 mm of the working length; only 20% (n = 58) were placed >0.5 mm beyond the working length. The odds of prevalence of extrusion (>0.5 mm) were significantly reduced by about 50% when cold lateral compaction or customization of GP were used. One operator produced 2.5 times more extruded root fillings than others. Curvature & length of root canal, apical size of prepared canal, as well as operator's preferred obturation technique had no significant influence on the prevalence of extrusion. Customization of GP was the sole factor to significantly reduce the prevalence of voids within the apical 5 mm of working length. Root filling extrusion was significantly influenced by 'operator' and was reduced by cold lateral compaction and customization of the master cone. Customization of master cone was the only factor that reduced voids apically.

Examining the Role of Trip Length in Commuter Decisions to Use Public Transportation

DOT National Transportation Integrated Search

2010-06-01

Traveler trip length has for years been used as a fundamental indicator of the best mix of transit modes and user perceptions of travel cost for transit versus auto. This study examines traveler trip lengths across transit modes, work trip duration f...

Recombination Catalysts for Hypersonic Fuels

NASA Technical Reports Server (NTRS)

Chinitz, W.

1998-01-01

The goal of commercially-viable access to space will require technologies that reduce propulsion system weight and complexity, while extracting maximum energy from the products of combustion. This work is directed toward developing effective nozzle recombination catalysts for the supersonic and hypersonic aeropropulsion engines used to provide such access to space. Effective nozzle recombination will significantly reduce rk=le length (hence, propulsion system weight) and reduce fuel requirements, further decreasing the vehicle's gross lift-off weight. Two such catalysts have been identified in this work, barium and antimony compounds, by developing chemical kinetic reaction mechanisms for these materials and determining the engine performance enhancement for a typical flight trajectory. Significant performance improvements are indicated, using only 2% (mole or mass) of these compounds in the combustor product gas.

Viral genome structures, charge, and sequences are optimal for capsid assembly

NASA Astrophysics Data System (ADS)

Hagan, Michael

2014-03-01

For many viruses, the spontaneous assembly of a capsid shell around the nu-cleic acid (NA) genome is an essential step in the viral life cycle. Capsid formation is a multicomponent, out-of-equilibrium assembly process for which kinetic effects and thermodynamic constraints compete to determine the outcome. Understand-ing how viral components drive highly efficient assembly under these constraints could promote biomedical efforts to block viral propagation, and would elucidate the factors controlling assembly in a wide range of systems containing proteins and polyelectrolytes. This talk will describe coarse-grained models of capsid proteins and NAs with which we investigate the dynamics and thermodynamics of virus assembly. In con-trast to recent theoretical models, we find that capsids spontaneously `overcharge' that is, the NA length which is kinetically and thermodynamically optimal possess-es a negative charge greater than the positive charge of the capsid. When applied to specific virus capsids, the calculated optimal NA lengths closely correspond to the natural viral genome lengths. These results suggest that the features included in this model (i.e. electrostatics, excluded volume, and NA tertiary structure) play key roles in determining assembly thermodynamics and consequently exert selec-tive pressure on viral evolution. I will then discuss mechanisms by which se-quence-specific interactions between NAs and capsid proteins promote selective encapsidation of the viral genome. This work was supported by NIH R01GM108021 and the Brandeis MRSEC NSF-MRSEC-0820492.

Design of a nanopatterned long focal-length planar focusing collector for concentrated solar power

NASA Astrophysics Data System (ADS)

Ding, Qing; Choubal, Aakash; Toussaint, Kimani C.

2017-02-01

Concentrated solar power (CSP) facilities heavily utilize parabolic troughs to collect and concentrate sunlight onto receivers that deliver solar thermal energy to heat engines for generating electricity. However, parabolic troughs are bulky and heavy and result in a large capital investment for CSP plants, thereby making it difficult for CSP technology to be competitive with photovoltaics. We present the design of a planar focusing collector (PFC) with focal length beyond the micron scale. The PFC design is based on the use of a nanostructured silver surface for linearly polarized singlewavelength light. The designed PFC consists of metallic nanogrooves on a dielectric substrate. The geometric properties, namely the width and depth, of a single-unit nanogroove allows for full control of the optical phase at desired spatial coordinates along the nanogroove short-axis for a single wavelength. Moreover, we show numerically that such phase control can be used to construct a phase front that mimics that of a cylindrical lens. In addition, we determine the concentration ratio by comparing the width of our PFC design to the cross-sectional width of its focal spot. We also determine the conversion efficiency at long focal lengths by evaluating the ratio of the collected optical power to the incoming optical power. Finally, we examine the focusing behavior across multiple wavelengths and angles of incidence. Our work shows how nano-optics and plasmonics could contribute to this important area of CSP technology.

Solution to certain problems in the failure of composite structures

NASA Astrophysics Data System (ADS)

Goodsell, Johnathan

The present work contains the solution of two problems in composite structures. In the first, an approximate elasticity solution for prediction of the displacement, stress and strain fields within the m-layer, symmetric and balanced angle-ply composite laminate of finite-width subjected anticlastic bending deformation is developed. The solution is shown to recover classical laminated plate theory predictions at interior regions of the laminate and thereby illustrates the boundary layer character of this interlaminar phenomenon. The results exhibit the anticipated response in congruence with the solutions for uniform axial extension and uniform temperature change, where divergence of the interlaminar shearing stress is seen to occur at the intersection of the free-edge and planes between lamina of +theta and -theta orientation. The analytical results show excellent agreement with the finite-element predictions for the same boundary-value problem and thereby provide an efficient and compact solution available for parametric studies of the influence of geometry and material properties. The solution is combined with previously developed solutions for uniform axial extension and uniform temperature change of the identical laminate and the combined solution is exercised to compare the relative magnitudes of free-edge phenomenon arising from the different loading conditions, to study very thick laminates and laminates where the laminate width is less than the laminate thickness. Significantly, it was demonstrated that the solution is valid for arbitrary stacking sequence and the solution was exercised to examine antisymmetric and non-symmetric laminates. Finally, the solution was exercised to determine the dimensions of the boundary layer for very large numbers of layers. It was found that the dimension of the boundary layer width in bending is approximately twice that in uniform axial extension and uniform temperature change. In the second, the intrinsic flaw concept is extended to the determination of the intrinsic flaw length and the prediction of performance variability in the 10-degree off-axis specimen. The intrinsic flaw is defined as a fracture mechanics-type, through-thickness planar crack extending in the fiber direction from the failure initiation site of length, a. The distribution of intrinsic flaw lengths is postulated from multiple tests of 10-degree off-axis specimens by calculating the length of flaw that would cause fracture at each measured failure site and failure load given the fracture toughness of the material. The intrinsic flaw lengths on the homogeneous and micromechanical scales for unnotched (no hole) and specimens containing a centrally-located, through-thickness circular hole are compared. 8 hole-diameters ranging from 1.00--12.7 mm are considered. On the micromechanical scale, the intrinsic flaw ranges between approximately 10 and 100 microns in length, on the order of the relevant microstructural dimensions. The intrinsic flaw lengths on the homogeneous scale are determined to be an order of magnitude greater than that on the micromechanical scale. The effect of variation in the fiber volume fraction on the intrinsic flaw length is also considered. In the strength predictions for the specimens, the intrinsic flaw crack geometry and probability density function of intrinsic flaw lengths calculated from the unnotched specimens allow fracture mechanics predictions of strength variability. The strength prediction is dependent on the flaw density, the number of flaws per unit length along the free-edge. The flaw density is established by matching the predicted strength with the experimental strength. The distribution of intrinsic flaw lengths is used with the strength variability of the unnotched and of open-hole specimens to determine the flaw density at each hole-size. The flaw density is shown to be related to the fabrication machining speed suggesting machining damage as a mechanism for the hole-size dependence of the flaw density. (Abstract shortened by UMI.)

Absolute-length determination of a long-baseline Fabry-Perot cavity by means of resonating modulation sidebands.

PubMed

Araya, A; Telada, S; Tochikubo, K; Taniguchi, S; Takahashi, R; Kawabe, K; Tatsumi, D; Yamazaki, T; Kawamura, S; Miyoki, S; Moriwaki, S; Musha, M; Nagano, S; Fujimoto, M K; Horikoshi, K; Mio, N; Naito, Y; Takamori, A; Yamamoto, K

1999-05-01

A new method has been demonstrated for absolute-length measurements of a long-baseline Fabry-Perot cavity by use of phase-modulated light. This method is based on determination of a free spectral range (FSR) of the cavity from the frequency difference between a carrier and phase-modulation sidebands, both of which resonate in the cavity. Sensitive response of the Fabry-Perot cavity near resonant frequencies ensures accurate determination of the FSR and thus of the absolute length of the cavity. This method was applied to a 300-m Fabry-Perot cavity of the TAMA gravitational wave detector that is being developed at the National Astronomical Observatory, Tokyo. With a modulation frequency of approximately 12 MHz, we successfully determined the absolute cavity length with resolution of 1 microm (3 x 10(-9) in strain) and observed local ground strain variations of 6 x 10(-8).

Fully transparent thin film transistors based on zinc oxide channel layer and molybdenum doped indium oxide electrodes

NASA Astrophysics Data System (ADS)

MÄ dzik, Mateusz; Elamurugu, Elangovan; Viegas, Jaime

2016-03-01

In this work we report the fabrication of thin film transistors (TFT) with zinc oxide channel and molybdenum doped indium oxide (IMO) electrodes, achieved by room temperature sputtering. A set of devices was fabricated, with varying channel width and length from 5μm to 300μm. Output and transfer characteristics were then extracted to study the performance of thin film transistors, namely threshold voltage and saturation current, enabling to determine optimal fabrication process parameters. Optical transmission in the UV-VIS-IR are also reported.

Proceedings of the Conference on the Design of Experiments in Army Research Development and Testing (39th) Held in Houston, Texas on 20-22 October 1993

DTIC Science & Technology

1994-06-01

determine thresholds for retry interval, window size, message length and arrival rate. Next a pilot test will be executed to screen each of the four...Figure 3. Prepilot Study Factors and Levels FUTURE WORK When software modifications are completed, the pilot test will be conducted to ex. plore the need...EXPERIMENTS IN ARMY RESEARCH DEVELOPMENT AND TESTING DTICS ELECTE JUL 081994 94-20739 G Approved for public rele•s; distribution unlimited. The findings

Targeting Prostate Cancer with Bifunctional Modulators of the Androgen Receptor

DTIC Science & Technology

2013-10-01

linker lengths were prepared and assessed to determine the impact of linker length on the activity of the molecules. HEK293T cells were transfected as...M. Determination of...15 derivatives were determined experimentally by radiolabeled competition binding assays using an extract 16 from Hi5 insect cells expressing an N

[Maternity leave and experience of working mothers in Lebanon].

PubMed

Saadé, N; Barbour, B; Salameh, P

2010-09-01

We conducted a cross-sectional study of 802 Lebanese mothers to evaluate effect of rapid return to work on their health and that of their child. Breastfeeding practices were also assessed. The duration of maternity leave was insufficient for 72.8% of the women. Rapid return to work could cause physical and psychological problems depending on the type of work. The average length of breastfeeding was 4.7 months and while the average desired length was 10.9 months. Breastfeeding depended on the duration of the maternity leave, the possibility of breaks for breastfeeding and the presence of nurseries at work. Urgent interventions are necessary to prolong maternity leave and promote breastfeeding among working women.

A review on setting appropriate reach length for biological assessment of boatable rivers

EPA Science Inventory

Researchers working on boatable rivers are presented with the task of selecting an appropriate stream length, or reach length, from which data will be collected. Ideally, the sampling effort applied is the minimum that will allow stated objectives to be addressed as required by a...

CHRIS: Hazard Assessment Handbook

DTIC Science & Technology

1977-12-12

3.10 Vectorial Addition of Sea and Wind Currents 50 B1 Flame Length for Gases Venting Through Holes 177 B2 Equivalent...determined are: • Flame length (flame height), • Safe distance for people (away from the flame) • Safe distance for people in fire-protective clothing (away...pencil so it can be erased) Determine the flame length from Figure B1, using the venting hole diameter and the curve corresponding to the specific

Analisis parametrico de las variables que influyen en el comportamiento adherente de las armaduras pretesas en el hormigon

NASA Astrophysics Data System (ADS)

Arbelaez Jaramillo, Cesar Augusto

Prestressed concrete technique through the use of prestressed reinforcement is extended in the precast concrete industry. This technique consists on casting a concrete element over a previously prestressed reinforcement, proceeding to release once the concrete has reached a determined strength so the prestressed stress introduced to the reinforcement be transmitted, by bond, to concrete. The bond behaviour of prestressed reinforcement includes two phenomena: prestress transmission from the reinforcement to concrete and anchorage of the reinforcement. This bond behaviour is characterized by mean of two lengths: transmission length and anchorage length. The good design of these lengths is a basic and fundamental aspect in the project of precast prestressed concrete elements to guaranty the appropriate transmission of prestress and to allow the anchorage of the reinforcement along the structural element service life. The influence of the parameters related to the concrete dosage on the transmission and anchorage lengths of prestressing strands have been analyzed. The ECADA test method has been applied. With this method the operations of transmission of prestress and anchorage of the reinforcement are sequentially done. The transmission and anchorage lengths are determined from the force control supported by the reinforcement testing series of specimens with different embedment lengths. The differentiation of the concepts of anchorage length without slips and with slips has been proposed. The relationship of the parameters of dosage with the bond stress and the registered slips during the processes of transmission and anchorage has been studied. Expressions to value the slips distribution of the reinforcement in the transmission zone and in the anchorage zone have been proposed. A study on the determination of the transmission length from the free reinforcement slip end has been done and the viability to experimentally determine the transmission length from the slips sequence in the pull-out end as a function of the embedment length has been verified. The experimental results have been compared with results and predictions from other authors and standards, and an expression to calculate the transmission length have been proposed. Finally, the bond behaviour of self-compacting concretes has been compared with the bond behaviour of traditional concretes.

Determination of axial and lateral exciton diffusion length in GaN by electron energy dependent cathodoluminescence

NASA Astrophysics Data System (ADS)

Hocker, Matthias; Maier, Pascal; Jerg, Lisa; Tischer, Ingo; Neusser, Gregor; Kranz, Christine; Pristovsek, Markus; Humphreys, Colin J.; Leute, Robert A. R.; Heinz, Dominik; Rettig, Oliver; Scholz, Ferdinand; Thonke, Klaus

2016-08-01

We demonstrate the application of low-temperature cathodoluminescence (CL) with high lateral, depth, and spectral resolution to determine both the lateral (i.e., perpendicular to the incident primary electron beam) and axial (i.e., parallel to the electron beam) diffusion length of excitons in semiconductor materials. The lateral diffusion length in GaN is investigated by the decrease of the GaN-related luminescence signal when approaching an interface to Ga(In)N based quantum well stripes. The axial diffusion length in GaN is evaluated from a comparison of the results of depth-resolved CL spectroscopy (DRCLS) measurements with predictions from Monte Carlo simulations on the size and shape of the excitation volume. The lateral diffusion length was found to be (95 ± 40) nm for nominally undoped GaN, and the axial exciton diffusion length was determined to be (150 ± 25) nm. The application of the DRCLS method is also presented on a semipolar (11 2 ¯ 2 ) sample, resulting in a value of (70 ± 10) nm in p-type GaN.

Core verbal working-memory capacity: the limit in words retained without covert articulation.

PubMed

Chen, Zhijian; Cowan, Nelson

2009-07-01

Verbal working memory may combine phonological and conceptual units. We disentangle their contributions by extending a prior procedure (Chen & Cowan, 2005) in which items recalled from lists of previously seen word singletons and of previously learned word pairs depended on the list length in chunks. Here we show that a constant capacity of about 3 chunks holds across list lengths and list types, provided that covert phonological rehearsal is prevented. What remains is a core verbal working-memory capacity.

Heavy Physical Work: Cardiovascular Load in Male Construction Workers

PubMed Central

Lunde, Lars-Kristian; Koch, Markus; Veiersted, Kaj Bo; Moen, Gunn-Helen; Wærsted, Morten; Knardahl, Stein

2016-01-01

This study aimed to elucidate cardiovascular loads (CVL) in construction workers during work and leisure by relative heart rate (RHR) over several days. Furthermore, we sought to evaluate the level of CVL in relation to individual factors, work ability, musculoskeletal pain and subjective general health. From a group of 255 construction workers responding to the baseline questionnaire, the CVL during work and leisure time was determined by recording RHR in 42 workers over 3–4 days. Almost 60% of the workday was spent below 20% RHR. The mean RHR during work for all participants was 16% RHR, with large differences between professions. On average, the 42 workers spent 14% of the workday at a RHR above 33%, and four subjects (10%) had a mean RHR above 33% during work. Eight (19%) of the participants had a mean length of their workday exceeding calculated maximal acceptable work time. Seven persons (17%) experienced on average one or more episode(s) of 5 min or more continuously above 33% RHR. The cardiovascular load at work was significantly associated with age and V˙O2max, but not with work ability, musculoskeletal pain or subjective general health. PMID:27023574

Electronic band gaps of confined linear carbon chains ranging from polyyne to carbyne

NASA Astrophysics Data System (ADS)

Shi, Lei; Rohringer, Philip; Wanko, Marius; Rubio, Angel; Waßerroth, Sören; Reich, Stephanie; Cambré, Sofie; Wenseleers, Wim; Ayala, Paola; Pichler, Thomas

2017-12-01

Ultralong linear carbon chains of more than 6000 carbon atoms have recently been synthesized within double-walled carbon nanotubes (DWCNTs), and they show a promising route to one-atom-wide semiconductors with a direct band gap. Theoretical studies predicted that this band gap can be tuned by the length of the chains, the end groups, and their interactions with the environment. However, different density functionals lead to very different values of the band gap of infinitely long carbyne. In this work, we applied resonant Raman excitation spectroscopy with more than 50 laser wavelengths to determine the band gap of long carbon chains encapsulated inside DWCNTs. The experimentally determined band gaps ranging from 2.253 to 1.848 eV follow a linear relation with Raman frequency. This lower bound is the smallest band gap of linear carbon chains observed so far. The comparison with experimental data obtained for short chains in gas phase or in solution demonstrates the effect of the DWCNT encapsulation, leading to an essential downshift of the band gap. This is explained by the interaction between the carbon chain and the host tube, which greatly modifies the chain's bond-length alternation.

LINDENS: A program for lineament length and density analysis*1

NASA Astrophysics Data System (ADS)

Casas, Antonio M.; Cortés, Angel L.; Maestro, Adolfo; Soriano, M. Asunción; Riaguas, Andres; Bernal, Javier

2000-11-01

Analysis of lineaments from satellite images normally includes the determination of their orientation and density. The spatial variation in the orientation and/or number of lineaments must be obtained by means of a network of cells, the lineaments included in each cell being analysed separately. The program presented in this work, LINDENS, allows the density of lineaments (number of lineaments per km 2 and length of lineaments per km 2) to be estimated. It also provides a tool for classifying the lineaments contained in different cells, so that their orientation can be represented in frequency histograms and/or rose diagrams. The input file must contain the planar coordinates of the beginning and end of each lineament. The density analysis is done by creating a network of square cells, and counting the number of lineaments that are contained within each cell, that have one of their ends within the cell or that cross-cut the cell boundary. The lengths of lineaments are then calculated. To obtain a representative density map the cell size must be fixed according to: (1) the average lineament length; (2) the distance between the lineaments; and (3) the boundaries of zones with low densities due to lithology or outcrop features. An example from the Neogene Duero Basin (Northern Spain) is provided to test the reliability of the density maps obtained with different cell sizes.

A simple model to demonstrate the electronic apex locator.

PubMed

Tinaz, A C; Alaçam, T; Topuz, O

2002-11-01

To describe and evaluate a newly developed model for demonstrating and teaching the use of electronic apex locators. A phantom model, master jaw model and extracted human teeth were used to construct the demonstration model with alginate impression material as the periapical conductive medium. The model was validated in a series of length determinations with apical foramina enlarged to 0.20, 0.30 and 0.45 mm diameter, and the stability of the model was evaluated up to 45 h after construction. All evaluations were conducted with the Root ZX apex locator with 2.65 and 5.25% NaOCl in the canals. Most length measurements were within 1 mm of actual root length (range: -2.2 to +0.21 mm) and did not change significantly over 45 h for teeth with foramina of 0.3 mm or less. Measurements for teeth with wide (0.45 mm) apices were stable up to 28 h. NaOCl concentration did not significantly affect the readings. A simple, inexpensive model can be manufactured from plastic dental jaws, natural teeth and alginate impression material to demonstrate electronic working length measurement. The model is stable for many hours and provides consistent results with different concentrations of NaOCl in the canal and various apical diameters. The model is a useful teaching aid but needs further evaluation and refinement before use in research applications.

Retirement on grounds of ill health: cross sectional survey in six organisations in United Kingdom.

PubMed

Poole, C J

1997-03-29

To assess the process and outcome of retirement due to ill health in six large organisations. Cross sectional study of the rate of retirement due to ill health by age, sex, and length of service. Principal diagnoses by age and length of service were also compared. Four public and two private large employers in the United Kingdom. Rates of retirement on the grounds of ill health by age, sex, and length of service of employees contributing to pension schemes. Rates of ill health retirement varied from 20 to 250 per 10,000 contributing members, and in two organisations the rate varied geographically within the same organisation. In the two organisations that provided data by sex, women retired at a greater rate than men under age 40 and over age 50. In four organisations the modal age or length of service coincided with enhancements in benefits. In the four that provided information on diagnoses, musculoskeletal and minor psychiatric illnesses were the most common reasons for retirement. The granting of ill health retirement benefits may not be determined by illness. There is a need for some employers and pension schemes to improve their processes for granting benefits. Doctors should be wary of conflicts of interest and work to guidelines when they advise pension schemes about the merits of an application for benefits.

Turbulence Generation in Combustion.

DTIC Science & Technology

1987-07-22

flame length . This work is summarized in this section. I1.1 Model for Turbulent Burning Velocity For a range of turbulence conditions including...Variable density effects have been added in an approximation, and an expression for the length of jet flames has been developed. The flame length expression...of jet mixing and jet flame length data using fractals, College of Engineering, Energy Report E-86-02, Comell University, Ithaca, NY, 1986. Results

TU-FG-BRB-02: The Impact of Using Dual-Energy CT for Determining Proton Stopping Powers: Comparison Between Theory and Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baer, E; Jee, K; Zhang, R

Purpose: To evaluate the clinical performance of dual-energy CT (DECT) in determining proton stopping power ratios (SPR) and demonstrate advantages over conventional single-energy CT (SECT). Methods: SECT and DECT scans of tissue-equivalent plastics as well as animal meat samples are performed with a Siemens SOMATOM Definition Flash. The methods of Schneider et al. (1996) and Bourque et al. (2014) are used to determine proton SPR on SECT and DECT images, respectively. Waterequivalent path length (WEPL) measurements of plastics and tissue samples are performed with a 195 MeV proton beam. WEPL values are determined experimentally using the depth-dose shift and dosemore » extinction methods. Results: Comparison between CT-based and experimental WEPL is performed for 12 tissue-equivalent plastic as well as 6 meat boxes containing animal liver, kidney, heart, stomach, muscle and bones. For plastic materials, results show a systematic improvement in determining SPR with DECT, with a mean absolute error of 0.4% compared to 1.7% for SECT. For the meat samples, preliminary results show the ability for DECT to determine WEPL with a mean absolute value of 1.1% over all meat boxes. Conclusion: This work demonstrates the potential in using DECT for determining proton SPR with plastic materials in a clinical context. Further work is required to show the benefits of DECT for tissue samples. While experimental uncertainties could be a limiting factor to show the benefits of DECT over SECT for the meat samples, further work is required to adapt the DECT formalism in the context of clinical use, where noise and artifacts play an important role.« less

Method and System for Determining Relative Displacement and Heading for Navigation

NASA Technical Reports Server (NTRS)

Sheikh, Suneel Ismail (Inventor); Pines, Darryll J. (Inventor); Conroy, Joseph Kim (Inventor); Spiridonov, Timofey N. (Inventor)

2015-01-01

A system and method for determining a location of a mobile object is provided. The system determines the location of the mobile object by determining distances between a plurality of sensors provided on a first and second movable parts of the mobile object. A stride length, heading, and separation distance between the first and second movable parts are computed based on the determined distances and the location of the mobile object is determined based on the computed stride length, heading, and separation distance.

Experimental investigation of the effect of insulator sleeve length on the time to pinch and multipinch formation in the plasma focus facility

NASA Astrophysics Data System (ADS)

Momenei, M.; Khodabakhshei, Z.; Panahi, N.; Mohammadi, M. A.

2017-03-01

The length of insulator sleeve is varied to investigate its effect on the pinch formation in the plasma focus facility. In this paper, the effect of insulator length on the time to pinch at various pressures and working voltages in the 1.15 kJ Mather type plasma focus is investigated. The results show that with 4.5 cm insulator length the time to pinch at all pressures is minimum. Other results also confirm that with increasing of pressure the time to pinch is increased. Moreover, with increasing working voltage the time to pinch is decreased. Pictures, captured using a digital single lens reflex (DSLR) Canon EOS 7D system, show that multipinch phenomenon is formed.

Can basic life support personnel safely determine that advanced life support is not needed?

PubMed

Cone, D C; Wydro, G C

2001-01-01

To determine whether firefighter/emergency medical technicians-basic (FF/EMT-Bs) staffing basic life support (BLS) ambulances in a two-tiered emergency medical services (EMS) system can safely determine when advanced life support (ALS) is not needed. This was a prospective, observational study conducted in two academic emergency departments (EDs) receiving patients from a large urban fire-based EMS system. Runs were studied to which ALS and BLS ambulances were simultaneously dispatched, with the patient transported by the BLS unit. Prospectively established criteria for potential need for ALS were used to determine whether the FF/EMT-B's decision to cancel the ALS unit was safe, and simple outcomes (admission rate, length of stay, mortality) were examined. In the system studied, BLS crews may cancel responding ALS units at their discretion; there are no protocols or medical criteria for cancellation. A convenience sample of 69 cases was collected. In 52 cases (75%), the BLS providers indicated that they cancelled the responding ALS unit because they did not feel ALS was needed. Of these, 40 (77%) met study criteria for ALS: 39 had potentially serious chief complaints, nine had abnormal vital signs, and ten had physical exam findings that warranted ALS. Forty-five (87%) received an intervention immediately upon ED arrival that could have been provided in the field by an ALS unit, and 16 (31%) were admitted, with a median length of stay of 3.3 days (range 1.1-73.4 days). One patient died. Firefighter/EMT-Bs, working without protocols or medical criteria, cannot always safely determine which patients may require ALS intervention.

Multi-window PIV measurements around a breathing manikin

NASA Astrophysics Data System (ADS)

Marr, David

2005-11-01

The presented work includes multi-scale measurements via a stereo article Image Velocimetry (PIV) system to view a pair of two-component windows of dissimilar scale using a varied focal length. These measurements are taken in the breathing zone of an isothermal breathing manikin (from mouth) in an environmental chamber of average office cubicle dimensions without ventilation and are analogous to an oscillatory jet. From these phase-averaged measurements, we can extract information concerning length scales, turbulence quantities and low dimensional information in order to both determine correlation between data at different length scales as well as continuing research in exposure assessment for the indoor environment. In this talk we will present these turbulence quantities and interpret their influence on the breathing zone. While the largest scale is that of the room itself, we find that the relevant spatial scales associated with the breathing zone are much lower in magnitude. In future experiments, we will expand the multi window PIV technique to include PIV window configured to obtain scales of order the cubicle simultaneously with those of the breathing zone. This will aid in our understanding of the combined impact of these multiple scales on occupant exposure in the indoor environment.

The association of occupational metals exposure and oxidative damage, telomere shortening in fitness equipments manufacturing workers

PubMed Central

KO, Jiunn-Liang; CHENG, Yu-Jung; LIU, Guan-Cen; HSIN, I-Lun; CHEN, Hsiu-Ling

2017-01-01

The welding is the major working process in fitness equipment manufacturing industry, and International Agency for Research on Cancer has classified welding fumes as possibly carcinogenic to humans (Group 2B). The present study aimed to evaluate associations between the occupational exposure of metals and oxidative damage and telomere length shortening in workers involved in the manufacture of fitness equipment. The blood metal concentrations were monitored and malondialdehyde (MDA), alkaline Comet assay was determined as oxidative damage in 117 workers from two representative fitness equipment manufacturing plants. MDA levels varied according to workers’ roles at the manufacturing plants, and showed a trend as cutting>painting>welding>administration workers. Welders had marginally shorter average telomere lengths than the administrative workers (p=0.058). Cr and Mn levels were significantly greater in welders than they were in administrative workers. There were significantly positive correlations between MDA and Cr and Mn levels, the major components of welding fume. However, the association would be eliminated if co-metals exposure were considered simultaneously. In future, telomere length and MDA might be potential biomarkers for predicting cardiovascular disease in co-metals exposed workers. PMID:28420806

Magnetical asymmetry effect in capacitively coupled plasmas: effects of the magnetic field gradient, pressure, and gap length

NASA Astrophysics Data System (ADS)

Yang, Shali; Chang, Lijie; Zhang, Ya; Jiang, Wei

2018-03-01

By applying the asymmetric magnetic field to a discharge, the dc self-bias and asymmetric plasma response can be generated even in a geometrically and electrically symmetric system. This is called magnetical asymmetric effect (MAE), which can be a new method to control the ion energy and flux independently (Yang et al 2017 Plasma Process. Polym. 14 1700087). In the present work, the effects of magnetic field gradient, gas pressure and gap length on MAE are investigated by using a one-dimensional implicit particle-in-cell/Monte Carlo collision simulation. It found that by appropriately increasing the magnetic field gradient and the gap length, the range of the self-bias voltage will be enlarged, which can be used as the effective approach to control the ion bombarding energy at the electrodes since the ion energy is determined by the voltage drop across the sheath. It also found that the ion flux asymmetry will disappear at high pressure when the magnetic field gradient is relative low, due to the frequent electron-neutral collisions can disrupt electron gyromotion and thus the MAE is greatly reduced.

28 CFR 811.4 - Determination of the obligation to register and the length of registration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Determination of the obligation to register and the length of registration. 811.4 Section 811.4 Judicial Administration COURT SERVICES AND... of not guilty by reason of insanity) or a determination that the person is a sexual psychopath; (2...

28 CFR 811.4 - Determination of the obligation to register and the length of registration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Determination of the obligation to register and the length of registration. 811.4 Section 811.4 Judicial Administration COURT SERVICES AND... of not guilty by reason of insanity) or a determination that the person is a sexual psychopath; (2...

Walkway Length Determination for Steady State Walking in Young and Older Adults

ERIC Educational Resources Information Center

Macfarlane, Pamela A.; Looney, Marilyn A.

2008-01-01

The primary purpose of this study was to determine acceleration (AC) and deceleration (DC) distances that would accommodate young and older adults walking at their preferred and fast speeds. A secondary purpose was to determine the minimal walkway length needed to record six steady state (SS) steps (three full gait cycles) for younger and older…

Does the Length of Elbow Flexors and Visual Feedback Have Effect on Accuracy of Isometric Muscle Contraction in Men after Stroke?

PubMed Central

Juodzbaliene, Vilma; Darbutas, Tomas; Skurvydas, Albertas

2016-01-01

The aim of the study was to determine the effect of different muscle length and visual feedback information (VFI) on accuracy of isometric contraction of elbow flexors in men after an ischemic stroke (IS). Materials and Methods. Maximum voluntary muscle contraction force (MVMCF) and accurate determinate muscle force (20% of MVMCF) developed during an isometric contraction of elbow flexors in 90° and 60° of elbow flexion were measured by an isokinetic dynamometer in healthy subjects (MH, n = 20) and subjects after an IS during their postrehabilitation period (MS, n = 20). Results. In order to evaluate the accuracy of the isometric contraction of the elbow flexors absolute errors were calculated. The absolute errors provided information about the difference between determinate and achieved muscle force. Conclusions. There is a tendency that greater absolute errors generating determinate force are made by MH and MS subjects in case of a greater elbow flexors length despite presence of VFI. Absolute errors also increase in both groups in case of a greater elbow flexors length without VFI. MS subjects make greater absolute errors generating determinate force without VFI in comparison with MH in shorter elbow flexors length. PMID:27042670

Does Core Length Taken per cc of Prostate Volume in Prostate Biopsy Affect the Diagnosis of Prostate Cancer?

PubMed

Deliktas, Hasan; Sahin, Hayrettin; Cetinkaya, Mehmet; Dere, Yelda; Erdogan, Omer; Baldemir, Ercan

2016-08-01

The aim of this study was to determine the minimal core length to be taken per cc of prostate volume for an effective prostate biopsy. A retrospective analysis was performed on the records of 379 patients who underwent a first prostate biopsy with 12 to 16 cores under transrectal ultrasound guidance between September 2012 and April 2015. For each patient, the core length per cc of the prostate and the percentage of sampled prostate volume were calculated, and these values were compared between the patients with and without prostate cancer. A total of 348 patients were included in the study. Cancer was determined in 26.4% of patients. The mean core length taken per cc of prostate and the percentage of sampled prostate volume were determined to be 3.40 ± 0.15 mm/cc (0.26%; range, 0.08-0.63 cc) in patients with cancer and 2.75 ± 0.08 mm/cc (0.20%; range, 0.04-0.66 cc) in patients without cancer (P = .000 and P = .000), respectively. Core length taken per cc of prostate of > 3.31 mm/cc was found to be related to an increase in the rates of prostate cancer diagnosis (odds ratio, 2.84; 95% confidence interval, 1.68-4.78). The rate of cancer determination for core length taken per cc of prostate of < 3.31 mm/cc was 19.9% and of > 3.31 mm/cc, 41.1%. Core length taken per cc of prostate and the percentage of sampled prostate volume are important morphometric parameters in the determination of prostate cancer. The results of study suggest a core length per cc of the prostate of > 3.31 mm/cc as a cutoff value for quality assurance. Copyright © 2016 Elsevier Inc. All rights reserved.

Does partial titin degradation affect sarcomere length non-uniformities and force in active and passive myofibrils?

PubMed

Joumaa, Venus; Bertrand, Fanny; Liu, Shuyue; Poscente, Sophia; Herzog, Walter

2018-05-16

The aim of this study was to determine the role of titin in preventing the development of sarcomere length non-uniformities following activation and after active and passive stretch, by determining the effect of partial titin degradation on sarcomere length non-uniformities and force in passive and active myofibrils. Selective partial titin degradation was performed using a low dose of trypsin. Myofibrils were set at a sarcomere length of 2.4 µm and then passively stretched to sarcomere lengths of 3.4 µm and 4.4 µm. In the active condition, myofibrils were set at a sarcomere length of 2.8µm, activated and actively stretched by 1 µm/sarcomere. The extent of sarcomere length non-uniformities was calculated for each sarcomere as the absolute difference between sarcomere length and the mean sarcomere length of the myofibril. Our main finding is that partial titin degradation does not increase sarcomere length non-uniformities after passive stretch and activation compared to when titin is intact, but increases the extent of sarcomere length non-uniformities after active stretch. Furthermore, when titin was partially degraded, active and passive stresses were substantially reduced. These results suggest that titin plays a crucial role in actively stretched myofibrils and is likely involved in active and passive force production.

A new model for force generation by skeletal muscle, incorporating work-dependent deactivation

PubMed Central

Williams, Thelma L.

2010-01-01

A model is developed to predict the force generated by active skeletal muscle when subjected to imposed patterns of lengthening and shortening, such as those that occur during normal movements. The model is based on data from isolated lamprey muscle and can predict the forces developed during swimming. The model consists of a set of ordinary differential equations, which are solved numerically. The model's first part is a simplified description of the kinetics of Ca2+ release from sarcoplasmic reticulum and binding to muscle protein filaments, in response to neural activation. The second part is based on A. V. Hill's mechanical model of muscle, consisting of elastic and contractile elements in series, the latter obeying known physiological properties. The parameters of the model are determined by fitting the appropriate mathematical solutions to data recorded from isolated lamprey muscle activated under conditions of constant length or rate of change of length. The model is then used to predict the forces developed under conditions of applied sinusoidal length changes, and the results compared with corresponding data. The most significant advance of this model is the incorporation of work-dependent deactivation, whereby a muscle that has been shortening under load generates less force after the shortening ceases than otherwise expected. In addition, the stiffness in this model is not constant but increases with increasing activation. The model yields a closer prediction to data than has been obtained before, and can thus prove an important component of investigations of the neural—mechanical—environmental interactions that occur during natural movements. PMID:20118315

2D beam hardening correction for micro-CT of immersed hard tissue

NASA Astrophysics Data System (ADS)

Davis, Graham; Mills, David

2016-10-01

Beam hardening artefacts arise in tomography and microtomography with polychromatic sources. Typically, specimens appear to be less dense in the center of reconstructions because as the path length through the specimen increases, so the X-ray spectrum is shifted towards higher energies due to the preferential absorption of low energy photons. Various approaches have been taken to reduce or correct for these artefacts. Pre-filtering the X-ray beam with a thin metal sheet will reduce soft energy X-rays and thus narrow the spectrum. Correction curves can be applied to the projections prior to reconstruction which transform measured attenuation with polychromatic radiation to predicted attenuation with monochromatic radiation. These correction curves can be manually selected, iteratively derived from reconstructions (this generally works where density is assumed to be constant) or derived from a priori information about the X-ray spectrum and specimen composition. For hard tissue specimens, the latter approach works well if the composition is reasonably homogeneous. In the case of an immersed or embedded specimen (e.g., tooth or bone) the relative proportions of mineral and "organic" (including medium and plastic container) species varies considerably for different ray paths and simple beam hardening correction does not give accurate results. By performing an initial reconstruction, the total path length through the container can be determined. By modelling the X-ray properties of the specimen, a 2D correction transform can then be created such that the predicted monochromatic attenuation can be derived as a function of both the measured polychromatic attenuation and the container path length.

Psychosocial work environment and prediction of quality of care indicators in one Canadian health center.

PubMed

Paquet, Maxime; Courcy, François; Lavoie-Tremblay, Mélanie; Gagnon, Serge; Maillet, Stéphanie

2013-05-01

Few studies link organizational variables and outcomes to quality indicators. This approach would expose operant mechanisms by which work environment characteristics and organizational outcomes affect clinical effectiveness, safety, and quality indicators. What are the predominant psychosocial variables in the explanation of organizational outcomes and quality indicators (in this case, medication errors and length of stay)? The primary objective of this study was to link the fields of evidence-based practice to the field of decision making, by providing an effective model of intervention to improve safety and quality. The study involved healthcare workers (n = 243) from 13 different care units of a university affiliated health center in Canada. Data regarding the psychosocial work environment (10 work climate scales, effort/reward imbalance, and social support) was linked to organizational outcomes (absenteeism, turnover, overtime), to the nurse/patient ratio and quality indicators (medication errors and length of stay) using path analyses. The models produced in this study revealed a contribution of some psychosocial factors to quality indicators, through an indirect effect of personnel- or human resources-related variables, more precisely: turnover, absenteeism, overtime, and nurse/patient ratio. Four perceptions of work environment appear to play an important part in the indirect effect on both medication errors and length of stay: apparent social support from supervisors, appreciation of the workload demands, pride in being part of one's work team, and effort/reward balance. This study reveals the importance of employee perceptions of the work environment as an indirect predictor of quality of care. Working to improve these perceptions is a good investment for loyalty and attendance. In general, better personnel conditions lead to fewer medication errors and shorter length of stay. © Sigma Theta Tau International.

30 CFR 1206.57 - Determination of transportation allowances.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Determination of transportation allowances... transportation allowances. (a) Arm's-length transportation contracts. (1)(i) For transportation costs incurred by a lessee under an arm's-length contract, the transportation allowance shall be the reasonable...

The determination of nonylphenol and its precursors in a trickling filter wastewater treatment process.

PubMed

Petrie, Bruce; McAdam, Ewan J; Whelan, Mick J; Lester, John N; Cartmell, Elise

2013-04-01

An ultra performance liquid chromatography method coupled to a triple quadrupole mass spectrometer was developed to determine nonylphenol and 15 of its possible precursors (nonylphenol ethoxylates and nonylphenol carboxylates) in aqueous and particulate wastewater matrices. Final effluent method detection limits for all compounds ranged from 1.4 to 17.4 ng l(-1) in aqueous phases and from 1.4 to 39.4 ng g(-1) in particulate phases of samples. The method was used to measure the performance of a trickling filter wastewater treatment works, which are not routinely monitored despite their extensive usage. Relatively good removals of nonylphenol were observed over the biological secondary treatment process, accounting for a 53 % reduction. However, only an 8 % reduction in total nonylphenolic compound load was observed. This was explained by a shortening in ethoxylate chain length which initiated production of shorter polyethoxylates ranging from 1 to 4 ethoxylate units in length in final effluents. Modelling the possible impact of trickling filter discharge demonstrated that the nonylphenol environmental quality standard may be exceeded in receiving waters with low dilution ratios. In addition, there is a possibility that the EQS can be exceeded several kilometres downstream of the mixing zone due to the biotransformation of readily degradable short-chained precursors. This accentuates the need to monitor 'non-priority' parent compounds in wastewater treatment works since monitoring nonylphenol alone can give a false indication of process performance. It is thus recommended that future process performance monitoring and optimisation is undertaken using the full suite of nonylphenolic moieties which this method can facilitate.

An Imaging System for Automated Characteristic Length Measurement of Debrisat Fragments

NASA Technical Reports Server (NTRS)

Moraguez, Mathew; Patankar, Kunal; Fitz-Coy, Norman; Liou, J.-C.; Sorge, Marlon; Cowardin, Heather; Opiela, John; Krisko, Paula H.

2015-01-01

The debris fragments generated by DebriSat's hypervelocity impact test are currently being processed and characterized through an effort of NASA and USAF. The debris characteristics will be used to update satellite breakup models. In particular, the physical dimensions of the debris fragments must be measured to provide characteristic lengths for use in these models. Calipers and commercial 3D scanners were considered as measurement options, but an automated imaging system was ultimately developed to measure debris fragments. By automating the entire process, the measurement results are made repeatable and the human factor associated with calipers and 3D scanning is eliminated. Unlike using calipers to measure, the imaging system obtains non-contact measurements to avoid damaging delicate fragments. Furthermore, this fully automated measurement system minimizes fragment handling, which reduces the potential for fragment damage during the characterization process. In addition, the imaging system reduces the time required to determine the characteristic length of the debris fragment. In this way, the imaging system can measure the tens of thousands of DebriSat fragments at a rate of about six minutes per fragment, compared to hours per fragment in NASA's current 3D scanning measurement approach. The imaging system utilizes a space carving algorithm to generate a 3D point cloud of the article being measured and a custom developed algorithm then extracts the characteristic length from the point cloud. This paper describes the measurement process, results, challenges, and future work of the imaging system used for automated characteristic length measurement of DebriSat fragments.

Association of Day Length and Weather Conditions with Physical Activity Levels in Older Community Dwelling People

PubMed Central

Witham, Miles D.; Donnan, Peter T.; Vadiveloo, Thenmalar; Sniehotta, Falko F.; Crombie, Iain K.; Feng, Zhiqiang; McMurdo, Marion E. T.

2014-01-01

Background Weather is a potentially important determinant of physical activity. Little work has been done examining the relationship between weather and physical activity, and potential modifiers of any relationship in older people. We therefore examined the relationship between weather and physical activity in a cohort of older community-dwelling people. Methods We analysed prospectively collected cross-sectional activity data from community-dwelling people aged 65 and over in the Physical Activity Cohort Scotland. We correlated seven day triaxial accelerometry data with daily weather data (temperature, day length, sunshine, snow, rain), and a series of potential effect modifiers were tested in mixed models: environmental variables (urban vs rural dwelling, percentage of green space), psychological variables (anxiety, depression, perceived behavioural control), social variables (number of close contacts) and health status measured using the SF-36 questionnaire. Results 547 participants, mean age 78.5 years, were included in this analysis. Higher minimum daily temperature and longer day length were associated with higher activity levels; these associations remained robust to adjustment for other significant associates of activity: age, perceived behavioural control, number of social contacts and physical function. Of the potential effect modifier variables, only urban vs rural dwelling and the SF-36 measure of social functioning enhanced the association between day length and activity; no variable modified the association between minimum temperature and activity. Conclusions In older community dwelling people, minimum temperature and day length were associated with objectively measured activity. There was little evidence for moderation of these associations through potentially modifiable health, environmental, social or psychological variables. PMID:24497925

Association of day length and weather conditions with physical activity levels in older community dwelling people.

PubMed

Witham, Miles D; Donnan, Peter T; Vadiveloo, Thenmalar; Sniehotta, Falko F; Crombie, Iain K; Feng, Zhiqiang; McMurdo, Marion E T

2014-01-01

Weather is a potentially important determinant of physical activity. Little work has been done examining the relationship between weather and physical activity, and potential modifiers of any relationship in older people. We therefore examined the relationship between weather and physical activity in a cohort of older community-dwelling people. We analysed prospectively collected cross-sectional activity data from community-dwelling people aged 65 and over in the Physical Activity Cohort Scotland. We correlated seven day triaxial accelerometry data with daily weather data (temperature, day length, sunshine, snow, rain), and a series of potential effect modifiers were tested in mixed models: environmental variables (urban vs rural dwelling, percentage of green space), psychological variables (anxiety, depression, perceived behavioural control), social variables (number of close contacts) and health status measured using the SF-36 questionnaire. 547 participants, mean age 78.5 years, were included in this analysis. Higher minimum daily temperature and longer day length were associated with higher activity levels; these associations remained robust to adjustment for other significant associates of activity: age, perceived behavioural control, number of social contacts and physical function. Of the potential effect modifier variables, only urban vs rural dwelling and the SF-36 measure of social functioning enhanced the association between day length and activity; no variable modified the association between minimum temperature and activity. In older community dwelling people, minimum temperature and day length were associated with objectively measured activity. There was little evidence for moderation of these associations through potentially modifiable health, environmental, social or psychological variables.

Calcaneotalar ratio: a new concept in the estimation of the length of the calcaneus.

PubMed

David, Vikram; Stephens, Terry J; Kindl, Radek; Ang, Andy; Tay, Wei-Han; Asaid, Rafik; McCullough, Keith

2015-01-01

Maintaining the calcaneal length after calcaneal fractures is vital to restoring the normal biomechanics of the foot, because it acts as an important lever arm to the plantarflexors of the foot. However, estimation of the length of the calcaneus to be reconstructed in comminuted calcaneal fractures can be difficult. We propose a new method to reliably estimate the calcaneal length radiographically by defining the calcaneotalar length ratio. A total of 100 ankle radiographs with no fracture in the calcaneus or talus taken in skeletally mature patients were reviewed by 6 observers. The anteroposterior lengths of the calcaneus and talus were measured, and the calcaneotalar length ratio was determined. The ratio was then used to estimate the length of the calcaneus. Interobserver reliability was determined using Cronbach's α coefficient and Pearson's correlation coefficient. The mean length of the calcaneus was 75 ± 0.6 mm, and the mean length of the talus was 59 ± 0.5 mm. The calcaneotalar ratio was 1.3. Using this ratio and multiplying it by the talar length, the mean average estimated length of the calcaneus was within 0.7 mm of the known calcaneal length. Cronbach's α coefficient and Pearson's correlation coefficient showed excellent interobserver reliability. The proposed calcaneotalar ratio is a new and reliable method to radiographically estimate the normal length of the calcaneus when reconstructing the calcaneus. Copyright © 2015 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Correlations of leaf area with length and width measurements of leaves of black oak, white oak, and sugar maple

Treesearch

Philip M. Wargo

1978-01-01

Correlations of leaf area with length, width, and length times width of leaves of black oak, white oak, and sugar maple were determined to see if length and/or width could be used as accurate estimators of leaf area. The correlation of length times width with leaf area was high (r > + .95) for all three species. The linear equation Y = a + bX, where X = length times...

Is DNA a worm-like chain in Couette flow? In search of persistence length, a critical review.

PubMed

Rittman, Martyn; Gilroy, Emma; Koohya, Hashem; Rodger, Alison; Richards, Adair

2009-01-01

Persistence length is the foremost measure of DNA flexibility. Its origins lie in polymer theory which was adapted for DNA following the determination of BDNA structure in 1953. There is no single definition of persistence length used, and the links between published definitions are based on assumptions which may, or may not be, clearly stated. DNA flexibility is affected by local ionic strength, solvent environment, bound ligands and intrinsic sequence-dependent flexibility. This article is a review of persistence length providing a mathematical treatment of the relationships between four definitions of persistence length, including: correlation, Kuhn length, bending, and curvature. Persistence length has been measured using various microscopy, force extension and solution methods such as linear dichroism and transient electric birefringence. For each experimental method a model of DNA is required to interpret the data. The importance of understanding the underlying models, along with the assumptions required by each definition to determine a value of persistence length, is highlighted for linear dichroism data, where it transpires that no model is currently available for long DNA or medium to high shear rate experiments.

Episiotomy increases perineal laceration length in primiparous women.

PubMed

Nager, C W; Helliwell, J P

2001-08-01

The aim of this study was to determine the clinical factors that contribute to posterior perineal laceration length. A prospective observational study was performed in 80 consenting, mostly primiparous women with term pregnancies. Posterior perineal lacerations were measured immediately after delivery. Numerous maternal, fetal, and operator variables were evaluated against laceration length and degree of tear. Univariate and multivariate regression analyses were performed to evaluate laceration length and parametric clinical variables. Nonparametric clinical variables were evaluated against laceration length by the Mann-Whitney U test. A multivariate stepwise linear regression equation revealed that episiotomy adds nearly 3 cm to perineal lacerations. Tear length was highly associated with the degree of tear (R = 0.86, R(2) = 0.73) and the risk of recognized anal sphincter disruption. None of 35 patients without an episiotomy had a recognized anal sphincter disruption, but 6 of 27 patients with an episiotomy did (P <.001). Body mass index was the only maternal or fetal variable that showed even a slight correlation with laceration length (R = 0.30, P =.04). Episiotomy is the overriding determinant of perineal laceration length and recognized anal sphincter disruption.

Fatigue during maximal sprint cycling: unique role of cumulative contraction cycles.

PubMed

Tomas, Aleksandar; Ross, Emma Z; Martin, James C

2010-07-01

Maximal cycling power has been reported to decrease more rapidly when performed with increased pedaling rates. Increasing pedaling rate imposes two constraints on the neuromuscular system: 1) decreased time for muscle excitation and relaxation and 2) increased muscle shortening velocity. Using two crank lengths allows the effects of time and shortening velocity to be evaluated separately. We conducted this investigation to determine whether the time available for excitation and relaxation or the muscle shortening velocity was mainly responsible for the increased rate of fatigue previously observed with increased pedaling rates and to evaluate the influence of other possible fatiguing constraints. Seven trained cyclists performed 30-s maximal isokinetic cycling trials using two crank lengths: 120 and 220 mm. Pedaling rate was optimized for maximum power for each crank length: 135 rpm for the 120-mm cranks (1.7 m x s(-1) pedal speed) and 109 rpm for the 220-mm cranks (2.5 m x s(-1) pedal speed). Power was recorded with an SRM power meter. Crank length did not affect peak power: 999 +/- 276 W for the 120-mm crank versus 1001 +/- 289 W for the 220-mm crank. Fatigue index was greater (58.6% +/- 3.7% vs 52.4% +/- 4.8%, P < 0.01), and total work was less (20.0 +/- 1.8 vs 21.4 +/- 2.0 kJ, P < 0.01) with the higher pedaling rate-shorter crank condition. Regression analyses indicated that the power for the two conditions was most highly related to cumulative work (r2 = 0.94) and to cumulative cycles (r2 = 0.99). These results support previous findings and confirm that pedaling rate, rather than pedal speed, was the main factor influencing fatigue. Our novel result was that power decreased by a similar increment with each crank revolution for the two conditions, indicating that each maximal muscular contraction induced a similar amount of fatigue.

The engineering of construction specifications for externally bonded FRP composites

NASA Astrophysics Data System (ADS)

Yang, Xinbao

This dissertation, consisting of six technical papers, presents the results of research on the theme of developing engineering and the construction specifications for externally bonded FRP composites. For particular, the work focuses on three critical aspects of the performance of FRP systems: fiber misalignment, corner radius, and lap splice length. Based on both experimental and theoretical investigations, the main contribution of this work is the development of recommendations on fiber misalignment limit, minimum corner radius, lap splice length to be used as guidance in the construction practice of FRP strengthening of concrete structures. The first three papers focus on the strength and stiffness degradation of CFRP laminates from fiber misalignment. It was concluded that misalignment affects strength more than stiffness. In practice, when all fibers in a laminate can be regarded as through fibers, it is recommended to use a reduction factor for strength and no reduction factor for stiffness to account for fiber misalignment. Findings from concrete beams strengthened with misaligned CFRP laminates verified these recommendations. The fourth and fifth papers investigate the effect of corner radius on the mechanical properties of CFRP laminates wrapped around a rectangular cross section. A unique reusable test device was fabricated to determine fiber stress and radial stress of CFRP laminates with different corner radii. Comparison performed with finite element analyses shows that the test method and the reusable device were viable and the stress concentration needs to be considered in FRP laminate wrapped corners. A minimum of 1.0 in. corner radius was recommended for practice. The sixth paper summarizes the research on the lap splice length of FRP laminates under static and repeated loads. Although a lap splice length of 1.5 in. is sufficient for CFRP laminates to develop the ultimate static tensile strength, a minimum of 4.0 in. is recommended in order to account for repeated loads.

Reflection of a TE-polarised Gaussian beam from a layered structure under conditions of resonance excitation of waveguide modes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sokolov, V I; Marusin, N V; Molchanova, S I

2014-11-30

The problem of reflection of a TE-polarised Gaussian light beam from a layered structure under conditions of resonance excitation of waveguide modes using a total internal reflection prism is considered. Using the spectral approach we have derived the analytic expressions for the mode propagation lengths, widths and depths of m-lines (sharp and narrow dips in the angular dependence of the specular reflection coefficient), depending on the structure parameters. It is shown that in the case of weak coupling, when the propagation lengths l{sub m} of the waveguide modes are mainly determined by the extinction coefficient in the film, the depthmore » of m-lines grows with the mode number m. In the case of strong coupling, when l{sub m} is determined mainly by the radiation of modes into the prism, the depth of m-lines decreases with increasing m. The change in the TE-polarised Gaussian beam shape after its reflection from the layered structure is studied, which is determined by the energy transfer from the incident beam into waveguide modes that propagate along the structure by the distance l{sub m}, are radiated in the direction of specular reflection and interfere with a part of the beam reflected from the working face of the prism. It is shown that this interference can lead to the field intensity oscillations near m-lines. The analysis of different methods for determining the parameters of thin-film structures is presented, including the measurement of mode angles θ{sub m} and the reflected beam shape. The methods are based on simultaneous excitation of a few waveguide modes in the film with a strongly focused monochromatic Gaussian beam, the waist width of which is much smaller than the propagation length of the modes. As an example of using these methods, the refractive index and the thickness of silicon monoxide film on silica substrate at the wavelength 633 nm are determined. (fibre and integrated-optical structures)« less

Dual-layer electrode-driven liquid crystal lens with electrically tunable focal length and focal plane

NASA Astrophysics Data System (ADS)

Zhang, Y. A.; Lin, C. F.; Lin, J. P.; Zeng, X. Y.; Yan, Q.; Zhou, X. T.; Guo, T. L.

2018-04-01

Electric-field-driven liquid crystal (ELC) lens with tunable focal length and their depth of field has been extensively applied in 3D display and imaging systems. In this work, a dual-layer electrode-driven liquid crystal (DELC) lens with electrically tunable focal length and controllable focal plane is demonstrated. ITO-SiO2-AZO electrodes with the dual-layer staggered structure on the top substrate are used as driven electrodes within a LC cell, which permits the establishment of an alternative controllability. The focal length of the DELC lens can be adjusted from 1.41 cm to 0.29 cm when the operating voltage changes from 15 V to 40 V. Furthermore, the focal plane of the DELC lens can selectively move by changing the driving method of the applied voltage to the next driven electrodes. This work demonstrates that the DELC lens has potential applications in imaging systems because of electrically tunable focal length and controllable focal plane.

30 CFR 1206.262 - Determination of transportation allowances.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Determination of transportation allowances... transportation allowances. (a) Arm's-length contracts. (1) For transportation costs incurred by a lessee pursuant to an arm's-length contract, the transportation allowance shall be the reasonable, actual costs...

30 CFR 1206.262 - Determination of transportation allowances.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Determination of transportation allowances... of transportation allowances. (a) Arm's-length contracts. (1) For transportation costs incurred by a lessee pursuant to an arm's-length contract, the transportation allowance shall be the reasonable, actual...

30 CFR 1206.262 - Determination of transportation allowances.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Determination of transportation allowances... transportation allowances. (a) Arm's-length contracts. (1) For transportation costs incurred by a lessee pursuant to an arm's-length contract, the transportation allowance shall be the reasonable, actual costs...

30 CFR 1206.461 - Determination of transportation allowances.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Determination of transportation allowances... of transportation allowances. (a) Arm's-length contracts. (1) For transportation costs incurred by a lessee pursuant to an arm's-length contract, the transportation allowance shall be the reasonable, actual...

30 CFR 1206.262 - Determination of transportation allowances.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Determination of transportation allowances... transportation allowances. (a) Arm's-length contracts. (1) For transportation costs incurred by a lessee pursuant to an arm's-length contract, the transportation allowance shall be the reasonable, actual costs...

Analysis of the age of Panax ginseng based on telomere length and telomerase activity.

PubMed

Liang, Jiabei; Jiang, Chao; Peng, Huasheng; Shi, Qinghua; Guo, Xiang; Yuan, Yuan; Huang, Luqi

2015-01-23

Ginseng, which is the root of Panax ginseng (Araliaceae), has been used in Oriental medicine as a stimulant and dietary supplement for more than 7,000 years. Older ginseng plants are substantially more medically potent, but ginseng age can be simulated using unscrupulous cultivation practices. Telomeres progressively shorten with each cell division until they reach a critical length, at which point cells enter replicative senescence. However, in some cells, telomerase maintains telomere length. In this study, to determine whether telomere length reflects ginseng age and which tissue is best for such an analysis, we examined telomerase activity in the main roots, leaves, stems, secondary roots and seeds of ginseng plants of known age. Telomere length in the main root (approximately 1 cm below the rhizome) was found to be the best indicator of age. Telomeric terminal restriction fragment (TRF) lengths, which are indicators of telomere length, were determined for the main roots of plants of different ages through Southern hybridization analysis. Telomere length was shown to be positively correlated with plant age, and a simple mathematical model was formulated to describe the relationship between telomere length and age for P. ginseng.

A Fossilized Energy Distribution of Lightning.

PubMed

Pasek, Matthew A; Hurst, Marc

2016-07-28

When lightning strikes soil, it may generate a cylindrical tube of glass known as a fulgurite. The morphology of a fulgurite is ultimately a consequence of the energy of the lightning strike that formed it, and hence fulgurites may be useful in elucidating the energy distribution frequency of cloud-to-ground lightning. Fulgurites from sand mines in Polk County, Florida, USA were collected and analyzed to determine morphologic properties. Here we show that the energy per unit length of lightning strikes within quartz sand has a geometric mean of ~1.0 MJ/m, and that the distribution is lognormal with respect to energy per length and frequency. Energy per length is determined from fulgurites as a function of diameter, and frequency is determined both by cumulative number and by cumulative length. This distribution parallels those determined for a number of lightning parameters measured in actual atmospheric discharge events, such as charge transferred, voltage, and action integral. This methodology suggests a potential useful pathway for elucidating lightning energy and damage potential of strikes.

A Fossilized Energy Distribution of Lightning

PubMed Central

Pasek, Matthew A.; Hurst, Marc

2016-01-01

When lightning strikes soil, it may generate a cylindrical tube of glass known as a fulgurite. The morphology of a fulgurite is ultimately a consequence of the energy of the lightning strike that formed it, and hence fulgurites may be useful in elucidating the energy distribution frequency of cloud-to-ground lightning. Fulgurites from sand mines in Polk County, Florida, USA were collected and analyzed to determine morphologic properties. Here we show that the energy per unit length of lightning strikes within quartz sand has a geometric mean of ~1.0 MJ/m, and that the distribution is lognormal with respect to energy per length and frequency. Energy per length is determined from fulgurites as a function of diameter, and frequency is determined both by cumulative number and by cumulative length. This distribution parallels those determined for a number of lightning parameters measured in actual atmospheric discharge events, such as charge transferred, voltage, and action integral. This methodology suggests a potential useful pathway for elucidating lightning energy and damage potential of strikes. PMID:27466230

Persistence length measurements from stochastic single-microtubule trajectories.

PubMed

van den Heuvel, M G L; Bolhuis, S; Dekker, C

2007-10-01

We present a simple method to determine the persistence length of short submicrometer microtubule ends from their stochastic trajectories on kinesin-coated surfaces. The tangent angle of a microtubule trajectory is similar to a random walk, which is solely determined by the stiffness of the leading tip and the velocity of the microtubule. We demonstrate that even a single-microtubule trajectory suffices to obtain a reliable value of the persistence length. We do this by calculating the variance in the tangent trajectory angle of an individual microtubule. By averaging over many individual microtubule trajectories, we find that the persistence length of microtubule tips is 0.24 +/- 0.03 mm.

Effects of geometric nonlinearity in an adhered microbeam for measuring the work of adhesion

NASA Astrophysics Data System (ADS)

Fang, Wenqiang; Mok, Joyce; Kesari, Haneesh

2018-03-01

Design against adhesion in microelectromechanical devices is predicated on the ability to quantify this phenomenon in microsystems. Previous research related the work of adhesion for an adhered microbeam to the beam's unadhered length, and as such, interferometric techniques were developed to measure that length. We propose a new vibration-based technique that can be easily implemented with existing atomic force microscopy tools or similar metrology systems. To make such a technique feasible, we analysed a model of the adhered microbeam using the nonlinear beam theory put forth by Woinowsky-Krieger. We found a new relation between the work of adhesion and the unadhered length; this relation is more accurate than the one by Mastrangelo & Hsu (Mastrangelo & Hsu 1993 J. Microelectromech. S., 2, 44-55. (doi:10.1109/84.232594)) which is commonly used. Then, we derived a closed-form approximate relationship between the microbeam's natural frequency and its unadhered length. Results obtained from this analytical formulation are in good agreement with numerical results from three-dimensional nonlinear finite-element analysis.

When Does Length Cause the Word Length Effect?

ERIC Educational Resources Information Center

Jalbert, Annie; Neath, Ian; Bireta, Tamra J.; Surprenant, Aimee M.

2011-01-01

The word length effect, the finding that lists of short words are better recalled than lists of long words, has been termed one of the benchmark findings that any theory of immediate memory must account for. Indeed, the effect led directly to the development of working memory and the phonological loop, and it is viewed as the best remaining…

Mechanical efficiency and force–time curve variation during repetitive jumping in trained and untrained jumpers.

PubMed

McBride, Jeffrey M; Snyder, James G

2012-10-01

Mechanical efficiency (ME), the ratio between work performed and energy expenditure, is a useful criterion in determining the roles of stored elastic energy and chemically deduced energy contributing to concentric performance in stretch-shortening cycle movements. Increased force production during the eccentric phase has been shown to relate to optimal muscle-tendon unit (MTU) length change and thus optimization of usage of stored elastic energy. This phenomenon, as previously reported, is reflected by higher jump heights and ME. The purpose of this investigation was to determine if ME may be different between trained and untrained jumpers and thus be accounted for by variation in force production in the eccentric phase as a reflection of usage of stored elastic energy during various jump types. This investigation involved 9 trained (age 20.7 ± 3.2 years, height 178.6 ± 5.3 cm, body mass 79.0 ± 5.5 kg) and 7 untrained (age 21.43 ± 2.37 years, height 176.17 ± 10.89 cm, body mass 78.8 ± 12.5 kg) male jumpers. Trained subjects were Division I track and field athletes who compete in the horizontal or vertical jumping or running events. Force-time and displacement-time curves were obtained during jumping to determine jump height and to calculate work performed and to observe possible differences in force production in the eccentric phase. Respiratory gases with a metabolic cart were obtained during jumping to calculate energy expenditure. ME was calculated as the ratio between work performed and energy expenditure. The subjects completed four sessions involving 20 repetitions of countermovement jumps (CMJ) and drop jumps from 40 cm (DJ40), 60 cm (DJ60) and 80 cm (DJ80). The trained jumpers jumped significantly higher in the CMJ, DJ40, DJ60 and DJ80 conditions than their untrained counterparts (p ≤ 0.05). ME was significantly higher in the trained in comparison to the untrained jumpers during DJ40. The amount of negative work during all jump types was significantly greater in the trained jumpers. There was a significant correlation between negative work and ME in the trained jumpers (r = 0.82) but not in the untrained jumpers (r = 0.54). The present study indicates that trained jumpers jump higher and have greater ME, possibly as a result of increased for production in the eccentric phase as a reflection of optimal MTU length change and thus increased usage of storage of elastic energy.

On the correlation between bond-length change and vibrational frequency shift in halogen-bonded complexes

NASA Astrophysics Data System (ADS)

Wang, Weizhou; Zhang, Yu; Ji, Baoming; Tian, Anmin

2011-06-01

The C-Hal (Hal = Cl, Br, or I) bond-length change and the corresponding vibrational frequency shift of the C-Hal stretch upon the C-Hal ⋯Y (Y is the electron donor) halogen bond formation have been determined by using density functional theory computations. Plots of the C-Hal bond-length change versus the corresponding vibrational frequency shift of the C-Hal stretch all give straight lines. The coefficients of determination range from 0.94366 to 0.99219, showing that the correlation between the C-Hal bond-length change and the corresponding frequency shift is very good in the halogen-bonded complexes. The possible effects of vibrational coupling, computational method, and anharmonicity on the bond-length change-frequency shift correlation are discussed in detail.

Procedure for Determining Turbulence Length Scales Using Hotwire Anemometry

NASA Technical Reports Server (NTRS)

El-Gabry, Lamyaa A.; Thurman, Douglas R.; Poinsatte, Philip E.

2014-01-01

Hotwire anemometers are used to measure instantaneous velocity from which the mean velocity and the velocity fluctuation can be determined. Using a hotwire system, it is possible to deduce not only the velocity components and their fluctuation but to also analyze the energy spectra and from that the turbulence length scales. In this experiment, hotwire anemometry is used to measure the flow field turbulence for an array of film cooling holes. The objective of this paper is to document the procedure that is used to reduce the instantaneous velocity measurements to determine the turbulence length scales using data from the film-cooling experiments to illustrate the procedure.

Effect of Reciprocating Systems and Working Lengths on Apical Microcrack Development: a micro-CT Study.

PubMed

Oliveira, Bruna Paloma de; Câmara, Andréa Cruz; Duarte, Daniel Amancio; Heck, Richard John; Antonino, Antonio Celso Dantas; Aguiar, Carlos Menezes

2017-01-01

The objective of this study was to evaluate the effect of root canal preparation with single-file reciprocating systems at different working lengths on the development of apical microcracks using micro-computed tomographic (micro-CT) imaging. Forty extracted human mandibular incisors were randomly assigned to 4 groups (n=10) according to the systems and working length used to prepare the root canals: Group A - WaveOne Gold at apical foramen (AF), Group B - WaveOne Gold 1 mm short of the AF (AF-1 mm), Group C - Unicone (AF) and Group D - Unicone (AF-1 mm). Micro-CT scanning was performed before and after root canal preparation at an isotropic resolution of 14 µm. Then, three examiners assessed the cross-sectional images generated to detect microcracks in the apical portion of the roots. Apical microcracks were visualized in 3, 1, 1, and 3 specimens in groups A, B, C, and D, respectively. All these microcracks observed after root canal preparation already existed prior to instrumentation, and no new apical microcrack was detected. For all groups, the number of slices presenting microcracks after root canal preparation was the same as before canal preparation. Root canal preparation with WaveOne Gold and Unicone, regardless of the working length, was not associated with apical microcrack formation.

Experimental investigation of flow and slip transition in nanochannels

NASA Astrophysics Data System (ADS)

Li, Zhigang; Li, Long; Mo, Jingwen

2014-11-01

Flow slip in nanochannels is sought in many applications, such as sea water desalination and molecular separation, because it can enhance fluid transport, which is essential in nanofluidic systems. Previous findings about the slip length for simple fluids at the nanoscale appear to be controversial. Some experiments and simulations showed that the slip length is independent of shear rate, which agrees with the prediction of classic slip theories. However, there is increasing work showing that slip length is shear rate dependent. In this work, we experimentally investigate the Poiseuille flows in nanochannels. It is found that the flow rate undergoes a transition between two linear regimes as the shear rate is varied. The transition indicates that the non-slip boundary condition is valid at low shear rate. When the shear rate is larger than a critical value, slip takes place and the slip length increases linearly with increasing shear rate before approaching a constant value. The results reported in this work can help advance the understanding of flow slip in nanochannels. This work was supported by the Research Grants Council of the Hong Kong Special Administrative Region under Grant Nos. 615710 and 615312. J. Mo was partially supported by the Postgraduate Scholarship through the Energy Program at HKUST.

Improving agreement between static method and dynamic formula for driven cast-in-place piles.

DOT National Transportation Integrated Search

2013-06-01

This study focuses on comparing the capacities and lengths of piling necessary as determined with a static method and with a dynamic formula. Pile capacities and their required lengths are determined two ways: 1) using a design and computed method, s...

Primitive-path statistics of entangled polymers: mapping multi-chain simulations onto single-chain mean-field models

NASA Astrophysics Data System (ADS)

Steenbakkers, Rudi J. A.; Tzoumanekas, Christos; Li, Ying; Liu, Wing Kam; Kröger, Martin; Schieber, Jay D.

2014-01-01

We present a method to map the full equilibrium distribution of the primitive-path (PP) length, obtained from multi-chain simulations of polymer melts, onto a single-chain mean-field ‘target’ model. Most previous works used the Doi-Edwards tube model as a target. However, the average number of monomers per PP segment, obtained from multi-chain PP networks, has consistently shown a discrepancy of a factor of two with respect to tube-model estimates. Part of the problem is that the tube model neglects fluctuations in the lengths of PP segments, the number of entanglements per chain and the distribution of monomers among PP segments, while all these fluctuations are observed in multi-chain simulations. Here we use a recently proposed slip-link model, which includes fluctuations in all these variables as well as in the spatial positions of the entanglements. This turns out to be essential to obtain qualitative and quantitative agreement with the equilibrium PP-length distribution obtained from multi-chain simulations. By fitting this distribution, we are able to determine two of the three parameters of the model, which govern its equilibrium properties. This mapping is executed for four different linear polymers and for different molecular weights. The two parameters are found to depend on chemistry, but not on molecular weight. The model predicts a constant plateau modulus minus a correction inversely proportional to molecular weight. The value for well-entangled chains, with the parameters determined ab initio, lies in the range of experimental data for the materials investigated.

An in vitro evaluation of the influence of neonatal endotracheal tube diameter and length on the work of breathing.

PubMed

Miyake, Fuyu; Suga, Rika; Akiyama, Takahiro; Namba, Fumihiko

2018-04-06

Neonates, particularly premature babies, are often managed with endotracheal intubation and subsequent mechanical ventilation to maintain adequate pulmonary gas exchange. There is no consensus on the standard length of endotracheal tube. Although a short tube reduces resistance and respiratory dead space, it is believed to increase the risk of accidental extubation. There are not entirely coherent data regarding the effect of endotracheal tube length on work of breathing in infants. The aim of this study was to evaluate the impact of neonatal endotracheal tube diameter and length on the work of breathing using an infant in vitro lung model. We assessed the work of breathing index and mechanical ventilation settings with various endotracheal tube diameters and lengths using the JTR100 in vitro infant lung model. The basic parameters of the model were breathing frequency of 20 per minutes, inspiratory-expiratory ratio of 1:3, and positive end-expiratory pressure of 5 cmH 2 O. In addition, the diaphragm driving pressure to maintain the set tidal volume was measured as the work of breathing index. The JTR100 was connected to the Babylog 8000plus through the endotracheal tube. Finally, we monitored the peak inspiratory pressure generated during assist-control volume guarantee mode with a targeted tidal volume of 10-30 mL. The diaphragm driving pressure using a 2.0-mm inner diameter tube was twice as high as that using a 4.0-mm inner diameter tube. To maintain the targeted tidal volume, a shorter tube reduced both the diaphragm driving pressure and ventilator-generated peak inspiratory pressure. The difference in the generated peak inspiratory pressure between the shortest and longest tubes was 5 cmH 2 O. In our infant lung model, a shorter tube resulted in a lower work of breathing and lower ventilator-generated peak inspiratory pressure. © 2018 John Wiley & Sons Ltd.

Determination of molecular configuration by debye length modulation.

PubMed

Vacic, Aleksandar; Criscione, Jason M; Rajan, Nitin K; Stern, Eric; Fahmy, Tarek M; Reed, Mark A

2011-09-07

Silicon nanowire field effect transistors (FETs) have emerged as ultrasensitive, label-free biodetectors that operate by sensing bound surface charge. However, the ionic strength of the environment (i.e., the Debye length of the solution) dictates the effective magnitude of the surface charge. Here, we show that control of the Debye length determines the spatial extent of sensed bound surface charge on the sensor. We apply this technique to different methods of antibody immobilization, demonstrating different effective distances of induced charge from the sensor surface.

Nonlinear effects on the natural modes of oscillation of a finite length inviscid fluid column, supplement 2

NASA Technical Reports Server (NTRS)

Lyell, M. J.; Zhang, L.

1994-01-01

The aspects of nonlinear behavior of a finite length liquid column is investigated with an emphasis on bridge dynamics. The primary objectives are to determine the nonlinear corrections to the interface shape of a naturally oscillating finite length liquid column and to determine the nonlinear corrections to the oscillation frequencies for various modes of oscillation. Application of the Lindstedt-Poincare expansion in conjunction with the domain perturbation techniques results in an hierarchical system of equations.

Estimation of Electron Temperature on Glass Spherical Tokamak (GLAST)

NASA Astrophysics Data System (ADS)

Hussain, S.; Sadiq, M.; Shah, S. I. W.; GLAST Team

2015-03-01

Glass Spherical Tokamak (GLAST) is a small spherical tokamak indigenously developed in Pakistan with an insulating vacuum vessel. A commercially available 2.45 GHz magnetron is used as pre-ionization source for plasma current startup. Different diagnostic systems like Rogowski coils, magnetic probes, flux loops, Langmuir probe, fast imaging and emission spectroscopy are installed on the device. The plasma temperature inside of GLAST, at the time of maxima of plasma current, is estimated by taking into account the Spitzer resistivity calculations with some experimentally determined plasma parameters. The plasma resistance is calculated by using Ohm's law with plasma current and loop voltage as experimentally determined inputs. The plasma resistivity is then determined by using length and area of the plasma column. Finally, the average plasma electron temperature is predicted to be 12.65eV for taking neon (Ne) as a working gas.

Correlation techniques to determine model form in robust nonlinear system realization/identification

NASA Technical Reports Server (NTRS)

Stry, Greselda I.; Mook, D. Joseph

1991-01-01

The fundamental challenge in identification of nonlinear dynamic systems is determining the appropriate form of the model. A robust technique is presented which essentially eliminates this problem for many applications. The technique is based on the Minimum Model Error (MME) optimal estimation approach. A detailed literature review is included in which fundamental differences between the current approach and previous work is described. The most significant feature is the ability to identify nonlinear dynamic systems without prior assumption regarding the form of the nonlinearities, in contrast to existing nonlinear identification approaches which usually require detailed assumptions of the nonlinearities. Model form is determined via statistical correlation of the MME optimal state estimates with the MME optimal model error estimates. The example illustrations indicate that the method is robust with respect to prior ignorance of the model, and with respect to measurement noise, measurement frequency, and measurement record length.

Genetic and transcriptomic dissection of the fiber length trait using a cotton (Gossypium hirsutum L.) MAGIC population.

USDA-ARS?s Scientific Manuscript database

Cotton fiber length is a key determinant of fiber quality for the textile industry. Improving cotton fiber length without reducing yield is one of the major goals for cotton breeding. However, genetic improvement of cotton fiber length by breeding has been a challenge due to narrow genetic diversit...

Can uptake length in strams be determined by nutrient addition experiments? Results from an interbiome comparison study

Treesearch

P. J Mulholland; J. L. Tanks; J. R. Webster; W. B. Bowden; W. K Dodds; S. V. Gregory; N. B Grimm; J. L. Meriam; J. L. Meyer; B. J. Peterson; H. M. Valett; W. M. Wollheim

2002-01-01

Nutrient uptake length is an important parnmeter tor quantifying nutrient cycling in streams. Although nutrient tracer additions are the preierred method for measuring uptake length under ambient nutrient concentrations, short-term nutrient addition experiments have more irequently been used to estimate uptake length in streams. Theoretical analysis of the relationship...

Modeling work zone crash frequency by quantifying measurement errors in work zone length.

PubMed

Yang, Hong; Ozbay, Kaan; Ozturk, Ozgur; Yildirimoglu, Mehmet

2013-06-01

Work zones are temporary traffic control zones that can potentially cause safety problems. Maintaining safety, while implementing necessary changes on roadways, is an important challenge traffic engineers and researchers have to confront. In this study, the risk factors in work zone safety evaluation were identified through the estimation of a crash frequency (CF) model. Measurement errors in explanatory variables of a CF model can lead to unreliable estimates of certain parameters. Among these, work zone length raises a major concern in this analysis because it may change as the construction schedule progresses generally without being properly documented. This paper proposes an improved modeling and estimation approach that involves the use of a measurement error (ME) model integrated with the traditional negative binomial (NB) model. The proposed approach was compared with the traditional NB approach. Both models were estimated using a large dataset that consists of 60 work zones in New Jersey. Results showed that the proposed improved approach outperformed the traditional approach in terms of goodness-of-fit statistics. Moreover it is shown that the use of the traditional NB approach in this context can lead to the overestimation of the effect of work zone length on the crash occurrence. Copyright © 2013 Elsevier Ltd. All rights reserved.

Interactions of genes and environment in myopia.

PubMed

Feldkämper, Marita; Schaeffel, Frank

2003-01-01

Myopia is a condition in which the eye is too long for the focal length of cornea and lens, and the plane of sharp focus ends up in front of the retina. Given that the growth of the length of the eye is normally controlled with extreme precision by an image-processing feedback mechanism in the retina, myopia can either be the result of inappropriate visual stimulation, genetically determined changes in the gain or offset of the feedback loops or of inappropriate responses of the target tissues. There is no doubt that an environmental component is involved and extended near work appears to be the major risk factor. However, there is also no doubt that myopia is inherited since myopic parents are much more likely to have myopic children, and myopia is far more frequent in Asian populations than in the USA or Europe, even if groups are compared that have performed similar amounts of near work. A number of systemic or ophthalmic diseases are associated with myopia, indicating that metabolic conditions may interfere either with the gains of the feedback loops or the responses of the target tissue, the sclera. Since there is still no therapy against myopia development, research is directed toward the identification of genes that control the axial elongation of the eye.

Accounting for care: exploring tensions and contradictions.

PubMed

Choiniere, Jacqueline A

2011-01-01

Within the context of neoliberal restructuring, accountability is primarily linked to efficiency, determined through standardized, numerically based technologies and focused on lengths of stay, utilization indicators, and the like. Disappearing from view in this approach is what is actually happening at the point of care for registered nurses. Grounded in semistructured interviews, this article casts a critical light on the tensions and contradictions experienced by nurses, arguing that instead of a more accountable, effective, or efficient system, this path is jeopardizing nurses' ability to provide needed care within healthy, supportive work environments, setting into motion a fundamental transformation of nursing practice.

Non-Fixed Investment in Voluntary Public Goods Games

NASA Astrophysics Data System (ADS)

Wang, Shuai; Xu, Zhaojin; Zhang, Lianzhong

2018-05-01

In this work, we introduce a non-fixed investment ratio to the public goods games in which players can determine whether or not to participate and how much money to invest into the common pool, and with it a new mechanism has been established. We explicitly demonstrate a different rockscissors- paper dynamics which is a consequence of this model. Meanwhile, it is shown how the mechanism of non-fixed investment ratio influences the players' decision. In addition, we found that the length of memory has an important effect on the average payoff of the population by this introduction.

Robot cable-compliant devices

NASA Technical Reports Server (NTRS)

Kerley, James J., Jr. (Inventor)

1990-01-01

A cable compliant robotic joint includes two U configuration cross section brackets with their U cross sections lying in different planes, one of their brackets being connected to a robot arm and the other to a tool. Additional angle brackets are displaced from the other brackets at corners of the robotic joint. All the brackets are connected by cable segments which lie in one or more planes which are perpendicular to the direction of tool travel as it approaches a work object. The compliance of the joint is determined by the cable segment characteristics, such as their length, material, angle, stranding, pretwisting, and prestressing.

Gas exchange and the coagulation system of the blood during the effect on the body of high concentrations of oxygen and carbon dioxide

NASA Technical Reports Server (NTRS)

Palosh, L.; Agadzhanyan, N. A.; Davydov, G. A.; Rybakov, B. K.; Sergiyenko, A. S.

1974-01-01

Maximum permissible concentrations of oxygen and carbon dioxide in a controlled atmosphere were determined by evaluating their effects on human gas exchange, blood coagulation, and tolerances to acute hypoxia, acceleration, and physical loads. It was found that functional disturbances depend on the concentration of respiratory gases and the length of stay in an altered atmosphere. By changing the atmospheric composition and by bringing the gaseous environment into accordance with the work and rest regimen and energy expenditures, the general reactivity of the body changes favorably.

Calibration of a universal indicated turbulence system

NASA Technical Reports Server (NTRS)

Chapin, W. G.

1977-01-01

Theoretical and experimental work on a Universal Indicated Turbulence Meter is described. A mathematical transfer function from turbulence input to output indication was developed. A random ergodic process and a Gaussian turbulence distribution were assumed. A calibration technique based on this transfer function was developed. The computer contains a variable gain amplifier to make the system output independent of average velocity. The range over which this independence holds was determined. An optimum dynamic response was obtained for the tubulation between the system pitot tube and pressure transducer by making dynamic response measurements for orifices of various lengths and diameters at the source end.

Survey of attitudes, materials and methods employed in endodontic treatment by general dental practitioners in North Jordan.

PubMed

Al-Omari, Wael M

2004-09-10

BACKGROUND: General dental practitioners provide the majority of endodontic treatment in Jordan. The aim of this study was to gather information on the methods, materials and attitudes employed in root canal treatment by dentists in North Jordan, in order to evaluate and improve the quality of current practice. METHODS: A questionnaire was posted to all registered general dental practitioners working in private practice in Irbid Governate in North Jordan (n = 181). The questionnaire included information on methods, materials and techniques used in endodontic treatment. RESULTS: Reply rate was 72% (n = 131). The results demonstrated that only five dentists used rubber dam occasionally and not routinely. The majority used cotton rolls for isolation solely or in combination with a high volume saliva ejector (n = 116). The most widely used irrigants were sodium hypochlorite and hydrogen peroxide, which were used by 32.9% (n = 43) and 33.6% (n = 44) of the respondents, respectively. Forty eight percent of the respondents (n = 61) used the cold lateral condensation technique for canal obturation, 31.3% (n = 41) used single cone, 9.9% (n = 13) used vertical condensation and 12.2% (n = 16) used paste or cement only for the obturation. The majority used zinc oxide eugenol as a sealer (72.5%). All, but one, respondents used hand instruments for canal preparation and the technique of choice was step back (52.7%). More than 50% (n = 70) of the dentists took one radiograph for determining the working length, whilst 22.9% (n = 30) did not take any radiograph at all. Most practitioners performed treatment in three visits for teeth with two or more root canals, and in two visits for teeth with a single root canal. CONCLUSIONS: This study indicates that dentists practicing in North Jordan do not comply with international quality standards and do not use recently introduced techniques. Many clinicians never take a radiograph for determining the working length and never used rubber dam or intra-canal medicaments.

Ballistic heat conduction and mass disorder in one dimension.

PubMed

Ong, Zhun-Yong; Zhang, Gang

2014-08-20

It is well-known that in the disordered harmonic chain, heat conduction is subballistic and the thermal conductivity (κ) scales asymptotically as lim(L--> ∞) κ ∝ L(0.5) where L is the chain length. However, using the nonequilibrium Green's function (NEGF) method and analytical modelling, we show that there exists a critical crossover length scale (LC) below which ballistic heat conduction (κ ∝ L) can coexist with mass disorder. This ballistic-to-subballistic heat conduction crossover is connected to the exponential attenuation of the phonon transmittance function Ξ i.e. Ξ(ω, L) = exp[-L/λ(ω)], where λ is the frequency-dependent attenuation length. The crossover length can be determined from the minimum attenuation length, which depends on the maximum transmitted frequency. We numerically determine the dependence of the transmittance on frequency and mass composition as well as derive a closed form estimate, which agrees closely with the numerical results. For the length-dependent thermal conductance, we also derive a closed form expression which agrees closely with numerical results and reproduces the ballistic to subballistic thermal conduction crossover. This allows us to characterize the crossover in terms of changes in the length, mass composition and temperature dependence, and also to determine the conditions under which heat conduction enters the ballistic regime. We describe how the mass composition can be modified to increase ballistic heat conduction.

Flame thermometry

NASA Astrophysics Data System (ADS)

Strojnik, Marija; Páez, Gonzalo; Granados, Juan C.

2006-08-01

We determine the temperature distribution within the flame as a function of position. We determined temperature distribution and the length of a flame by dual-wavelength thermometry, at 470 nm and 515 nm. The error percentages on the temperature and the flame length measurements are 1.9% as compared with the predicted thermodynamic results.

Lifetime and diffusion length measurements on silicon material and solar cells

NASA Technical Reports Server (NTRS)

Othmer, S.; Chen, S. C.

1978-01-01

Experimental methods were evaluated for the determination of lifetime and diffusion length in silicon intentionally doped with potentially lifetime-degrading impurities found in metallurgical grade silicon, impurities which may be residual in low-cost silicon intended for use in terrestrial flat-plate arrays. Lifetime measurements were made using a steady-state photoconductivity method. Diffusion length determinations were made using short-circuit current measurements under penetrating illumination. Mutual consistency among all experimental methods was verified, but steady-state photoconductivity was found preferable to photoconductivity decay at short lifetimes and in the presence of traps. The effects of a number of impurities on lifetime in bulk material, and on diffusion length in cells fabricated from this material, were determined. Results are compared with those obtained using different techniques. General agreement was found in terms of the hierarchy of impurities which degrade the lifetime.

Relationship between body composition, leg strength, anaerobic power, and on-ice skating performance in division I men's hockey athletes.

PubMed

Potteiger, Jeffrey A; Smith, Dean L; Maier, Mark L; Foster, Timothy S

2010-07-01

The purpose of this study was to examine relationships between laboratory tests and on-ice skating performance in division I men's hockey athletes. Twenty-one men (age 20.7 +/- 1.6 years) were assessed for body composition, isokinetic force production in the quadriceps and hamstring muscles, and anaerobic muscle power via the Wingate 30-second cycle ergometer test. Air displacement plethysmography was used to determine % body fat (%FAT), fat-free mass (FFM), and fat mass. Peak torque and total work during 10 maximal effort repetitions at 120 degrees .s were measured during concentric muscle actions using an isokinetic dynamometer. Muscle power was measured using a Monark cycle ergometer with resistance set at 7.5% of body mass. On-ice skating performance was measured during 6 timed 89-m sprints with subjects wearing full hockey equipment. First length skate (FLS) was 54 m, and total length skate (TLS) was 89 m with fastest and average skating times used in the analysis. Correlation coefficients were used to determine relationships between laboratory testing and on-ice performance. Subjects had a body mass of 88.8 +/- 7.8 kg and %FAT of 11.9 +/- 4.6. First length skate-Average and TLS-Average skating times were moderately correlated to %FAT ([r = 0.53; p = 0.013] and [r = 0.57; p = 0.007]) such that a greater %FAT was related to slower skating speeds. First length skate-Fastest was correlated to Wingate percent fatigue index (r = -0.48; p = 0.027) and FLS-Average was correlated to Wingate peak power per kilogram body mass (r = -0.43; p = 0.05). Laboratory testing of select variables can predict skating performance in ice hockey athletes. This information can be used to develop targeted and effective strength and conditioning programs that will improve on-ice skating speed.

Evaluation of the morphological characteristic and sex differences of sternum by multi-detector computed tomography.

PubMed

Ateşoğlu, Sibel; Deniz, Mustafa; Uslu, Ayşe İmge

2018-01-18

Sternum is one of the skeleton parts which have frequently congenital anomalies and variations are commonly used by researchers in determining sex. We evaluated the morphological characteristics and sex-related changes of the sternum in adult individuals using multidetector CT in our study. 200 adults (103 female and 97 male) aged between 18-87 years were evaluated. Utilizing the morphological characteristics of the sternum based on the multi-slice images; length, width and the thickness of Manubrium, length, width and the thickness of Corpus Sterni, total length of Sternum, Sternal angle, Sternal index, length of the xiphoid process, the thickness of xiphoid process, the number of indents of xiphoid process were measured and a total of 20 parameters were evaluated by adding age, height and weight to these variables. The mean length of the manubrium, the length of corpus sterni, the length of total sternum, sternal index, sternal angle were found in females 46.7±5.1,86.6±9.7, 133.1±1.1, 54.47±10.0 and 163.75±5.79; in males 51.2±6, 102.4±13.3, 154.1±13.1, 50.11±10.02 and 162.21±6.17, respectively. We found that Hyrtl's law and Sternal index did not provide adequate accuracy for sex determination in our patients. It has been detected that the length of the Manubrium alone is not helpful for individual samples. Total length of the sternum was found to be more reliable than the length of the Manubrium and the length of corpus Sterni. We determined Sternal cleft and Sternal foramen as 0.5% and 3.5%, respectively. We suggest that the Morphometric standards cannot be universally applied and can demonstrate individual differences. The standard rules must be implemented for every population.

The Influence of Spring Length on the Physical Parameters of Simple Harmonic Motion

ERIC Educational Resources Information Center

Triana, C. A.; Fajardo, F.

2012-01-01

The aim of this work is to analyse the influence of spring length on the simple harmonic motion of a spring-mass system. In particular, we study the effect of changing the spring length on the elastic constant "[kappa]", the angular frequency "[omega]" and the damping factor "[gamma]" of the oscillations. To characterize the behaviour of these…

Modeling and self-assembly behavior of PEG-PLA-PEG triblock copolymers in aqueous solution

NASA Astrophysics Data System (ADS)

Wu, Xiaohan; Li, Suming; Coumes, Fanny; Darcos, Vincent; Lai Kee Him, Joséphine; Bron, Patrick

2013-09-01

A series of poly(ethylene glycol)-polylactide-poly(ethylene glycol) (PEG-PLA-PEG) triblock copolymers with symmetric or asymmetric chain structures were synthesized by combination of ring-opening polymerization and copper-catalyzed click chemistry. The resulting copolymers were used to prepare self-assembled aggregates by dialysis. Various architectures such as nanotubes, polymersomes and spherical micelles were observed from transmission electron microscopy (TEM), cryo-TEM and atomic force microscopy (AFM) measurements. The formation of diverse aggregates is explained by modeling from the angle of both geometry and thermodynamics. From the angle of geometry, a ``blob'' model based on the Daoud-Cotton model for star polymers is proposed to describe the aggregate structures and structural changes with copolymer composition and molar mass. In fact, the copolymer chains extend in aqueous medium to form single layer polymersomes to minimize the system's free energy if one of the two PEG blocks is short enough. The curvature of polymersomes is dependent on the chain structure of copolymers, especially on the length of PLA blocks. A constant branch number of aggregates (f) is thus required to preserve the morphology of polymersomes. Meanwhile, the aggregation number (Nagg) determined from the thermodynamics of self-assembly is roughly proportional to the total length of polymer chains. Comparing f to Nagg, the aggregates take the form of polymersomes if Nagg ~ f, and change to nanotubes if Nagg > f to conform to the limits from both curvature and aggregation number. The length of nanotubes is mainly determined by the difference between Nagg and f. However, the hollow structure becomes unstable when both PEG segments are too long, and the aggregates eventually collapse to yield spherical micelles. Therefore, this work gives new insights into the self-assembly behavior of PEG-PLA-PEG triblock copolymers in aqueous solution which present great interest for biomedical and pharmaceutical applications.A series of poly(ethylene glycol)-polylactide-poly(ethylene glycol) (PEG-PLA-PEG) triblock copolymers with symmetric or asymmetric chain structures were synthesized by combination of ring-opening polymerization and copper-catalyzed click chemistry. The resulting copolymers were used to prepare self-assembled aggregates by dialysis. Various architectures such as nanotubes, polymersomes and spherical micelles were observed from transmission electron microscopy (TEM), cryo-TEM and atomic force microscopy (AFM) measurements. The formation of diverse aggregates is explained by modeling from the angle of both geometry and thermodynamics. From the angle of geometry, a ``blob'' model based on the Daoud-Cotton model for star polymers is proposed to describe the aggregate structures and structural changes with copolymer composition and molar mass. In fact, the copolymer chains extend in aqueous medium to form single layer polymersomes to minimize the system's free energy if one of the two PEG blocks is short enough. The curvature of polymersomes is dependent on the chain structure of copolymers, especially on the length of PLA blocks. A constant branch number of aggregates (f) is thus required to preserve the morphology of polymersomes. Meanwhile, the aggregation number (Nagg) determined from the thermodynamics of self-assembly is roughly proportional to the total length of polymer chains. Comparing f to Nagg, the aggregates take the form of polymersomes if Nagg ~ f, and change to nanotubes if Nagg > f to conform to the limits from both curvature and aggregation number. The length of nanotubes is mainly determined by the difference between Nagg and f. However, the hollow structure becomes unstable when both PEG segments are too long, and the aggregates eventually collapse to yield spherical micelles. Therefore, this work gives new insights into the self-assembly behavior of PEG-PLA-PEG triblock copolymers in aqueous solution which present great interest for biomedical and pharmaceutical applications. Electronic supplementary information (ESI) available: 1H-NMR, DOSY, FTIR, and GPC measurements, methods and results of the copolymers in PEG-PLA-PEG synthesis. See DOI: 10.1039/c3nr02899b

Surface photovoltage measurements and finite element modeling of SAW devices.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Donnelly, Christine

2012-03-01

Over the course of a Summer 2011 internship with the MEMS department of Sandia National Laboratories, work was completed on two major projects. The first and main project of the summer involved taking surface photovoltage measurements for silicon samples, and using these measurements to determine surface recombination velocities and minority carrier diffusion lengths of the materials. The SPV method was used to fill gaps in the knowledge of material parameters that had not been determined successfully by other characterization methods. The second project involved creating a 2D finite element model of a surface acoustic wave device. A basic form ofmore » the model with the expected impedance response curve was completed, and the model is ready to be further developed for analysis of MEMS photonic resonator devices.« less

Ex vivo accuracy of an apex locator using digital signal processing in primary teeth.

PubMed

Leonardo, Mário Roberto; da Silva, Lea Assed Bezerra; Nelson-Filho, Paulo; da Silva, Raquel Assed Bezerra; Lucisano, Marília Pacífico

2009-01-01

The purpose of this study was to evaluate ex vivo the accuracy an electronic apex locator during root canal length determination in primary molars. One calibrated examiner determined the root canal length in 15 primary molars (total=34 root canals) with different stages of root resorption. Root canal length was measured both visually with the placement of a K-file 1 mm short of the apical foramen or the apical resorption bevel, and electronically using an electronic apex locator (Digital Signal Processing). Data were analyzed statistically using the intraclass correlation (ICC) test. Comparing the actual and electronic root canal length measurements in the primary teeth showed a high correlation (ICC=0.95). The Digital Signal Processing apex locator is useful and accurate for apex foramen location during root canal length measurement in primary molars.

Instant messaging at the hospital: supporting articulation work?

PubMed

Iversen, Tobias Buschmann; Melby, Line; Toussaint, Pieter

2013-09-01

Clinical work is increasingly fragmented and requires extensive articulation and coordination. Computer systems may support such work. In this study, we investigate how instant messaging functions as a tool for supporting articulation work at the hospital. This paper aims to describe the characteristics of instant messaging communication in terms of number and length of messages, distribution over time, and the number of participants included in conversations. We also aim to determine what kind of articulation work is supported by analysing message content. Analysis of one month's worth of instant messages sent through the perioperative coordination and communication system at a Danish hospital. Instant messaging was found to be used extensively for articulation work, mostly through short, simple conversational exchanges. It is used particularly often for communication concerning the patient, specifically, the coordination and logistics of patient care. Instant messaging is used by all actors involved in the perioperative domain. Articulation work and clinical work are hard to separate in a real clinical setting. Predefined messages and strict workflow design do not suffice when supporting communication in the context of collaborative clinical work. Flexibility is of vital importance, and this needs to be reflected in the design of supportive communication systems. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Fetal kidney length as a useful adjunct parameter for better determination of gestational age.

PubMed

Ugur, Mete G; Mustafa, Aynur; Ozcan, Huseyin C; Tepe, Neslihan B; Kurt, Huseyin; Akcil, Emre; Gunduz, Reyhan

2016-05-01

To determine the validity of fetal kidney length and amniotic fluid index (AFI) in labor dating.  This prospective study included 180 pregnant women followed up in the outpatient clinic at the Department of Obstetrics and Gynecology, Gaziantep University, Turkey, between January 2014 and January 2015. The gestational age (GA) was estimated by early fetal ultrasound measures and last menstrual period. Routine fetal biometric parameters, fetal kidney length, and amniotic fluid index were measured. We studied the correlation between fetal kidney length, amniotic fluid index, and gestational age.  The mean gestational age depending on last menstrual period and early ultrasound was 31.98±4.29 (24-39 weeks). The mean kidney length was 35.66±6.61 (19-49 mm). There was a significant correlation between gestational age and fetal kidney length (r=0.947, p=0.001). However, there was a moderate negative correlation between GA and AFI. Adding fetal kidney length to the routine biometrics improved the effectiveness of the model used to estimate GA (R2=0.965 to R2=0.987).  Gestational age can be better predicted by adding fetal kidney length to other routine parameters.

Influence of Age, Maturity, and Body Size on the Spatiotemporal Determinants of Maximal Sprint Speed in Boys.

PubMed

Meyers, Robert W; Oliver, Jon L; Hughes, Michael G; Lloyd, Rhodri S; Cronin, John B

2017-04-01

Meyers, RW, Oliver, JL, Hughes, MG, Lloyd, RS, and Cronin, JB. Influence of age, maturity, and body size on the spatiotemporal determinants of maximal sprint speed in boys. J Strength Cond Res 31(4): 1009-1016, 2017-The aim of this study was to investigate the influence of age, maturity, and body size on the spatiotemporal determinants of maximal sprint speed in boys. Three-hundred and seventy-five boys (age: 13.0 ± 1.3 years) completed a 30-m sprint test, during which maximal speed, step length, step frequency, contact time, and flight time were recorded using an optical measurement system. Body mass, height, leg length, and a maturity offset represented somatic variables. Step frequency accounted for the highest proportion of variance in speed (∼58%) in the pre-peak height velocity (pre-PHV) group, whereas step length explained the majority of the variance in speed (∼54%) in the post-PHV group. In the pre-PHV group, mass was negatively related to speed, step length, step frequency, and contact time; however, measures of stature had a positive influence on speed and step length yet a negative influence on step frequency. Speed and step length were also negatively influence by mass in the post-PHV group, whereas leg length continued to positively influence step length. The results highlighted that pre-PHV boys may be deemed step frequency reliant, whereas those post-PHV boys may be marginally step length reliant. Furthermore, the negative influence of body mass, both pre-PHV and post-PHV, suggests that training to optimize sprint performance in youth should include methods such as plyometric and strength training, where a high neuromuscular focus and the development force production relative to body weight are key foci.

An anthropometric study to evaluate the correlation between the occlusal vertical dimension and length of the thumb.

PubMed

Basnet, Bishal Babu; Parajuli, Prakash Kumar; Singh, Raj Kumar; Suwal, Pramita; Shrestha, Pragya; Baral, Dharanidhar

2015-01-01

Establishment of proper occlusal vertical dimension (OVD) is one of the important tasks for successful prosthodontic therapy. An ideal method for determining OVD in terms of cost, time, and instrument requirements has been sought in prosthodontics by various investigators. However, no such single method has been formulated. In the current anthropometric study, the relationship of the length of the thumb to the OVD was tested in two ethnic groups of Nepal, Aryans, and Mongoloids. The result of this study can be useful in determining proper OVD in edentulous patients. The primary aim of the present study was to evaluate the correlation between the length of the thumb and OVD in Aryan and Mongoloid ethnic groups. The secondary aim was to compare the correlation between OVD and other anatomic measurements (eye-ear distance and pupil-to-rima oris distance) in these ethnicities. The OVD, thumb length, eye-ear distance and distance between pupil of eye and rima oris were measured in a total of 500 adult dentulous volunteers. The correlation between OVD and thumb length as well as other anatomic measurements was checked with Pearson's product moment correlation coefficient. Linear regression analysis was performed to determine the relationship of OVD to the length of the thumb. The thumb length was significantly (P≤0.05) correlated with strong and positive values (Pearson's coefficient =0.874 in the whole population, 0.826 in Aryans, and 0.944 in Mongoloids). Regression analysis showed that thumb length was significantly related to OVD in both ethnic groups. Within the limitations of the present study, the result implies that thumb length can be used as an adjunct for establishing OVD in the edentulous patients.

Crustal dynamics project session 4 validation and intercomparison experiments 1979-1980 report

NASA Technical Reports Server (NTRS)

Liebrecht, P.; Kolenkiewicz, R.; Ryan, J.; Hothem, L.

1983-01-01

As part of the Crustal Dynamics Project, an experiment was performed to verify the ability of Satellite Laser Ranging (SLR), Very Long Baseline interferometry (VLBI) and Doppler Satellite Positioning System (Doppler) techniques to estimate the baseline distances between several locations. The Goddard Space Flight Center (GSFC) lasers were in operation at all five sites available to them. The ten baselines involved were analyzed using monthly orbits and various methods of selecting data. The standard deviation of the monthly SLR baseline lengths was at the 7 cm level. The GSFC VLBI (Mark III) data was obtained during three separate experiments. November 1979 at Haystack and Owens Valley, and April and July 1980 at Haystack, Owens Valley, and Fort Davis. Repeatability of the VLBI in determining baseline lengths was calculated to be at the 2 cm level. Jet Propulsion Laboratory (JPL) VLBI (Mark II) data was acquired on the Owens Valley to Goldstone baseline on ten occasions between August 1979 and November 1980. The repeatability of these baseline length determinations was calculated to be at the 5 cm level. National Geodetic Survey (NGS) Doppler data was acquired at all five sites in January 1980. Repeatability of the Doppler determined baseline lengths results were calculated at approximately 30 cm. An intercomparison between baseline distances and associated parameters was made utilizing SLR, VLBI, and Doppler results on all available baselines. The VLBI and SLR length determinations were compared on four baselines with a resultant mean difference of -1 cm and a maximum difference of 12 cm. The SLR and Doppler length determinations were compared on ten baselines with a resultant mean difference of about 30 cm and a maximum difference of about 60 cm. The VLBI and Doppler lengths from seven baselines showed a resultant mean difference of about 30 cm and maximum difference of about 1 meter. The intercomparison of baseline orientation parameters were consistent with past analysis.

Sulfide bonded atomic radii

NASA Astrophysics Data System (ADS)

Gibbs, G. V.; Ross, N. L.; Cox, D. F.

2017-09-01

The bonded radius, r b(S), of the S atom, calculated for first- and second-row non-transition metal sulfide crystals and third-row transition metal sulfide molecules and crystals indicates that the radius of the sulfur atom is not fixed as traditionally assumed, but that it decreases systematically along the bond paths of the bonded atoms with decreasing bond length as observed in an earlier study of the bonded radius of the oxygen atom. When bonded to non-transition metal atoms, r b(S) decreases systematically with decreasing bond length from 1.68 Å when the S atom is bonded to the electropositive VINa atom to 1.25 Å when bonded to the more electronegative IVP atom. In the case of transition metal atoms, rb(S) likewise decreases with decreasing bond length from 1.82 Å when bonded to Cu and to 1.12 Å when bonded to Fe. As r b(S) is not fixed at a given value but varies substantially depending on the bond length and the field strength of the bonded atoms, it is apparent that sets of crystal and atomic sulfide atomic radii based on an assumed fixed radius for the sulfur atom are satisfactory in that they reproduce bond lengths, on the one hand, whereas on the other, they are unsatisfactory in that they fail to define the actual sizes of the bonded atoms determined in terms of the minima in the electron density between the atoms. As such, we urge that the crystal chemistry and the properties of sulfides be studied in terms of the bond lengths determined by adding the radii of either the atomic and crystal radii of the atoms but not in terms of existing sets of crystal and atomic radii. After all, the bond lengths were used to determine the radii that were experimentally determined, whereas the individual radii were determined on the basis of an assumed radius for the sulfur atom.

Ion acceleration in electrostatic collisionless shock: on the optimal density profile for quasi-monoenergetic beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boella, E.; Fiúza, F.; Novo, A. Stockem

Here, a numerical study on ion acceleration in electrostatic shock waves is presented, with the aim of determining the best plasma configuration to achieve quasi-monoenergetic ion beams in laser-driven systems. It was recently shown that tailored near-critical density plasmas characterized by a long-scale decreasing rear density profile lead to beams with low energy spread (Fiúza et al 2012 Phys. Rev. Lett. 109 215001). In this work, a detailed parameter scan investigating different plasma scale lengths is carried out. As result, the optimal plasma spatial scale length that allows for minimizing the energy spread while ensuring a significant reflection of ionsmore » by the shock is identified. Furthermore, a new configuration where the required profile has been obtained by coupling micro layers of different densities is proposed. Lastly, results show that this new engineered approach is a valid alternative, guaranteeing a low energy spread with a higher level of controllability.« less

Differential Scanning Calorimetric (DSC) Analysis of Rotary Nickel-Titanium (NiTi) Endodontic File (RNEF)

NASA Astrophysics Data System (ADS)

Wu, Ray Chun Tung; Chung, C. Y.

2012-12-01

To determine the variation of A f along the axial length of rotary nickel-titanium endodontic files (RNEF). Three commercial brands of 4% taper RNEF: GTX (#20, 25 mm, Dentsply Tulsa Dental Specialties, Tulsa, OK, USA), K3 (#25, 25 mm) and TF (Twisted File #25, 27 mm) (Sybron Kerr, Orange, CA, USA) were cut into segments at 4 mm increment from the working tip. Regional specimens were measured for differential heat-flow over thermal cycling, generally with continuous heating or cooling (5 °C/min) and 5 min hold at set temperatures (start, finish temperatures): GTX: -55, 90 °C; K3: -55, 45 °C; TF: -55, 60 °C; using differential scanning calorimeter. This experiment demonstrated regional differences in A f along the axial length of GTX and K3 files. Similar variation was not obvious in the TF samples. A contributory effect of regional difference in strain-hardening due to grinding and machining during manufacturing is proposed.

High throughput exploration of process-property linkages in Al-6061 using instrumented spherical microindentation and microstructurally graded samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weaver, Jordan S.; Khosravani, Ali; Castillo, Andrew

Recent spherical nanoindentation protocols have proven robust at capturing the local elastic-plastic response of polycrystalline metal samples at length scales much smaller than the grain size. In this work, we extend these protocols to length scales that include multiple grains to recover microindentation stress-strain curves. These new protocols are first established in this paper and then demonstrated for Al-6061 by comparing the measured indentation stress-strain curves with the corresponding measurements from uniaxial tension tests. More specifically, the scaling factors between the uniaxial yield strength and the indentation yield strength was determined to be about 1.9, which is significantly lower thanmore » the value of 2.8 used commonly in literature. Furthermore, the reasons for this difference are discussed. Second, the benefits of these new protocols in facilitating high throughput exploration of process-property relationships are demonstrated through a simple case study.« less

High throughput exploration of process-property linkages in Al-6061 using instrumented spherical microindentation and microstructurally graded samples

DOE PAGES

Weaver, Jordan S.; Khosravani, Ali; Castillo, Andrew; ...

2016-06-14

Recent spherical nanoindentation protocols have proven robust at capturing the local elastic-plastic response of polycrystalline metal samples at length scales much smaller than the grain size. In this work, we extend these protocols to length scales that include multiple grains to recover microindentation stress-strain curves. These new protocols are first established in this paper and then demonstrated for Al-6061 by comparing the measured indentation stress-strain curves with the corresponding measurements from uniaxial tension tests. More specifically, the scaling factors between the uniaxial yield strength and the indentation yield strength was determined to be about 1.9, which is significantly lower thanmore » the value of 2.8 used commonly in literature. Furthermore, the reasons for this difference are discussed. Second, the benefits of these new protocols in facilitating high throughput exploration of process-property relationships are demonstrated through a simple case study.« less

Eliciting Challenges on Social Connectedness among Filipino Nurse Returnees: A Cross-Sectional Mixed-Method Research.

PubMed

Cortez, Mary Jane L; Del Rosario, Christian V; Diño, Michael Joseph S

2016-01-01

This cross-sectional study utilized a nested concurrent design to determine the association of Filipino nurse returnees' length of stay since they returned and their social connectedness as well as the essence of communication from their perspective. The respondents, who are Filipino nurses (n = 107) who worked abroad and returned to the Philippines for good, were employed from June to July of 2015 via referrals from colleges and institutions in Metro Manila and Bulacan areas in the Philippines. The quantitative results revealed, in one hand, significant but weak correlation between the respondent's length of stay and social connectedness (r = 0.224, p = 0.021, α = 0.05). On the other hand, three themes were generated from the qualitative analysis, namely, (1) Taking-In, (2) Taking-Hold, and (3) Letting-Go. The Social Connection System (SCS) provides a visual depiction of the social connectedness of a person. This research is geared towards the understanding of the interesting phenomenon of migration and social coherence of Filipino professionals.

Speckle size in optical Fourier domain imaging

NASA Astrophysics Data System (ADS)

Lamouche, G.; Vergnole, S.; Bisaillon, C.-E.; Dufour, M.; Maciejko, R.; Monchalin, J.-P.

2007-06-01

As in conventional time-domain optical coherence tomography (OCT), speckle is inherent to any Optical Fourier Domain Imaging (OFDI) of biological tissue. OFDI is also known as swept-source OCT (SS-OCT). The axial speckle size is mainly determined by the OCT resolution length and the transverse speckle size by the focusing optics illuminating the sample. There is also a contribution from the sample related to the number of scatterers contained within the probed volume. In the OFDI data processing, there is some liberty in selecting the range of wavelengths used and this allows variation in the OCT resolution length. Consequently the probed volume can be varied. By performing measurements on an optical phantom with a controlled density of discrete scatterers and by changing the probed volume with different range of wavelengths in the OFDI data processing, there is an obvious change in the axial speckle size, but we show that there is also a less obvious variation in the transverse speckle size. This work contributes to a better understanding of speckle in OCT.

Binding of alkylphenols and alkylated non-phenolics to the rainbow trout (Oncorhynchus mykiss) plasma sex steroid-binding protein.

PubMed

Tollefsen, K-E

2007-09-01

Alkylphenols are well-known endocrine disrupters, mediating effects through the estrogen receptor (ER). Although the estrogenic properties of the alkylphenols are well documented, alternative mechanisms of action are poorly described. In the present work, the interaction of a range of alkyl-substituted phenols and alkyl-substituted non-phenolics with the rainbow trout (Oncorhynchus mykiss) sex steroid-binding protein (rtSBP) were determined by competitive ligand-binding studies. The role of alkyl chain length and branching, substituent position, number of alkylated groups, and the requirement of a phenolic ring structure were assessed. The results showed that the rtSBP binds to most chemical structures tested, although the highest affinity was obtained for mono-substituted alkylphenols with a chain length of four to eight methyl groups. Interestingly, rtSBP binding was also observed for non-phenolic compounds such as 4-t-butylcyclohexanol and 4-t-butylnitrobenzene suggesting that the rtSBP has a broad binding specificity for alkylphenols and alkylated non-phenolics.

Binding of alkylphenols and alkylated non-phenolics to rainbow trout (Oncorhynchus mykiss) hepatic estrogen receptors.

PubMed

Tollefsen, Knut-Erik; Julie Nilsen, Anja

2008-02-01

Alkylphenols are well-known endocrine disrupters, mediating effects through the estrogen receptor (ER). In the present work, the interaction of alkylphenols and alkylated non-phenolics with hepatic rainbow trout (Oncorhynchus mykiss) estrogen receptors (rtERs) was determined. The role of alkyl chain length and branching, substituent position, number of alkylated groups, and the requirement of a phenolic ring structure was assessed. The results showed that the rtERs bound most alkylphenols, although with 20,000 to 2 million times lower affinity than the endogenous estrogen 17beta-estradiol. Mono-substituted alkylphenols with moderate (C4-C6) and long (C8 and C12) alkyl chain length in the para position exhibited the highest affinity for the rtERs. Substitution with multiple alkyl groups, presence of substituents in the ortho- and meta-position, and lack of a hydroxyl group on the benzene ring reduced the binding affinity. The rtERs resembled the reported binding specificity of the human ER for alkylphenols, although some exceptions were identified.

Scaling and modeling of turbulent suspension flows

NASA Technical Reports Server (NTRS)

Chen, C. P.

1989-01-01

Scaling factors determining various aspects of particle-fluid interactions and the development of physical models to predict gas-solid turbulent suspension flow fields are discussed based on two-fluid, continua formulation. The modes of particle-fluid interactions are discussed based on the length and time scale ratio, which depends on the properties of the particles and the characteristics of the flow turbulence. For particle size smaller than or comparable with the Kolmogorov length scale and concentration low enough for neglecting direct particle-particle interaction, scaling rules can be established in various parameter ranges. The various particle-fluid interactions give rise to additional mechanisms which affect the fluid mechanics of the conveying gas phase. These extra mechanisms are incorporated into a turbulence modeling method based on the scaling rules. A multiple-scale two-phase turbulence model is developed, which gives reasonable predictions for dilute suspension flow. Much work still needs to be done to account for the poly-dispersed effects and the extension to dense suspension flows.

Ion acceleration in electrostatic collisionless shock: on the optimal density profile for quasi-monoenergetic beams

DOE PAGES

Boella, E.; Fiúza, F.; Novo, A. Stockem; ...

2018-02-01

Here, a numerical study on ion acceleration in electrostatic shock waves is presented, with the aim of determining the best plasma configuration to achieve quasi-monoenergetic ion beams in laser-driven systems. It was recently shown that tailored near-critical density plasmas characterized by a long-scale decreasing rear density profile lead to beams with low energy spread (Fiúza et al 2012 Phys. Rev. Lett. 109 215001). In this work, a detailed parameter scan investigating different plasma scale lengths is carried out. As result, the optimal plasma spatial scale length that allows for minimizing the energy spread while ensuring a significant reflection of ionsmore » by the shock is identified. Furthermore, a new configuration where the required profile has been obtained by coupling micro layers of different densities is proposed. Lastly, results show that this new engineered approach is a valid alternative, guaranteeing a low energy spread with a higher level of controllability.« less

Suppression of the sonic heat transfer limit in high-temperature heat pipes

NASA Astrophysics Data System (ADS)

Dobran, Flavio

1989-08-01

The design of high-performance heat pipes requires optimization of heat transfer surfaces and liquid and vapor flow channels to suppress the heat transfer operating limits. In the paper an analytical model of the vapor flow in high-temperature heat pipes is presented, showing that the axial heat transport capacity limited by the sonic heat transfer limit depends on the working fluid, vapor flow area, manner of liquid evaporation into the vapor core of the evaporator, and lengths of the evaporator and adiabatic regions. Limited comparisons of the model predictions with data of the sonic heat transfer limits are shown to be very reasonable, giving credibility to the proposed analytical approach to determine the effect of various parameters on the axial heat transport capacity. Large axial heat transfer rates can be achieved with large vapor flow cross-sectional areas, small lengths of evaporator and adiabatic regions or a vapor flow area increase in these regions, and liquid evaporation in the evaporator normal to the main flow.

The effect of stochastic modeling of ionospheric effect on the various lengths of baseline determination

NASA Astrophysics Data System (ADS)

Kwon, J.; Yang, H.

2006-12-01

Although GPS provides continuous and accurate position information, there are still some rooms for improvement of its positional accuracy, especially in the medium and long range baseline determination. In general, in case of more than 50 km baseline length, the effect of ionospheric delay is the one causing the largest degradation in positional accuracy. For example, the ionospheric delay in terms of double differenced mode easily reaches 10 cm with baseline length of 101 km. Therefore, many researchers have been tried to mitigate/reduce the effect using various modeling methods. In this paper, the optimal stochastic modeling of the ionospheric delay in terms of baseline length is presented. The data processing has been performed by constructing a Kalman filter with states of positions, ambiguities, and the ionospheric delays in the double differenced mode. Considering the long baseline length, both double differenced GPS phase and code observations are used as observables and LAMBDA has been applied to fix the ambiguities. Here, the ionospheric delay is stochastically modeled by well-known Gaussian, 1st and 3rd order Gauss-Markov process. The parameters required in those models such as correlation distance and time is determined by the least-square adjustment using ionosphere-only observables. Mainly the results and analysis from this study show the effect of stochastic models of the ionospheric delay in terms of the baseline length, models, and parameters used. In the above example with 101 km baseline length, it was found that the positional accuracy with appropriate ionospheric modeling (Gaussian) was about ±2 cm whereas it reaches about ±15 cm with no stochastic modeling. It is expected that the approach in this study contributes to improve positional accuracy, especially in medium and long range baseline determination.

Does smooth muscle in an intact airway undergo length adaptation during a sustained change in transmural pressure?

PubMed

Ansell, Thomas K; McFawn, Peter K; McLaughlin, Robert A; Sampson, David D; Eastwood, Peter R; Hillman, David R; Mitchell, Howard W; Noble, Peter B

2015-03-01

In isolated airway smooth muscle (ASM) strips, an increase or decrease in ASM length away from its current optimum length causes an immediate reduction in force production followed by a gradual time-dependent recovery in force, a phenomenon termed length adaptation. In situ, length adaptation may be initiated by a change in transmural pressure (Ptm), which is a primary physiological determinant of ASM length. The present study sought to determine the effect of sustained changes in Ptm and therefore, ASM perimeter, on airway function. We measured contractile responses in whole porcine bronchial segments in vitro before and after a sustained inflation from a baseline Ptm of 5 cmH2O to 25 cmH2O, or deflation to -5 cmH2O, for ∼50 min in each case. In one group of airways, lumen narrowing and stiffening in response to electrical field stimulation (EFS) were assessed from volume and pressure signals using a servo-controlled syringe pump with pressure feedback. In a second group of airways, lumen narrowing and the perimeter of the ASM in situ were determined by anatomical optical coherence tomography. In a third group of airways, active tension was determined under isovolumic conditions. Both inflation and deflation reduced the contractile response to EFS. Sustained Ptm change resulted in a further decrease in contractile response, which returned to baseline levels upon return to the baseline Ptm. These findings reaffirm the importance of Ptm in regulating airway narrowing. However, they do not support a role for ASM length adaptation in situ under physiological levels of ASM lengthening and shortening. Copyright © 2015 the American Physiological Society.

The correspondence between proximal phalanx morphology and locomotion: implications for inferring the locomotor behavior of fossil catarrhines.

PubMed

Rein, Thomas R

2011-11-01

Phalanges are considered to be highly informative in the reconstruction of extinct primate locomotor behavior since these skeletal elements directly interact with the substrate during locomotion. Variation in shaft curvature and relative phalangeal length has been linked to differences in the degree of suspension and overall arboreal locomotor activities. Building on previous work, this study investigated these two skeletal characters in a comparative context to analyze function, while taking evolutionary relationships into account. This study examined the correspondence between proportions of suspension and overall substrate usage observed in 17 extant taxa and included angle of curvature and relative phalangeal length. Predictive models based on these traits are reported. Published proportions of different locomotor behaviors were regressed against each phalangeal measurement and a size proxy. The relationship between each behavior and skeletal trait was investigated using ordinary least-squares, phylogenetic generalized least-squares (pGLS), and two pGLS transformation methods to determine the model of best-fit. Phalangeal curvature and relative length had significant positive relationships with both suspension and overall arboreal locomotion. Cross-validation analyses demonstrated that relative length and curvature provide accurate predictions of relative suspensory behavior and substrate usage in a range of extant species when used together in predictive models. These regression equations provide a refined method to assess the amount of suspensory and overall arboreal locomotion characterizing species in the catarrhine fossil record. Copyright © 2011 Wiley-Liss, Inc.

Influence of Turbulence Parameters, Reynolds Number, and Body Shape on Stagnation-Region Heat Transfer

NASA Technical Reports Server (NTRS)

Vanfossen, G. James; Simoneau, Robert J.; Ching, Chan Y.

1994-01-01

The purpose of the present work was threefold: (1) to determine if a free-stream turbulence length scale existed that would cause the greatest augmentation in stagnation-region heat transfer over laminar levels; (2) to investigate the effect of velocity gradient on stagnation-region heat transfer augmentation by free-stream turbulence; and (3) to develop a prediction tool for stagnation heat transfer in the presence of free-stream turbulence. Heat transfer was measured in the stagnation region of four models with elliptical leading edges that had ratios of major to minor axes of 1:1, 1.5:1, 2.25:1, and 3:1. Five turbulence-generating grids were fabricated; four were square mesh, biplane grids made from square bars. The fifth grid was an array of fine parallel wires that were perpendicular to the model spanwise direction. Heat transfer data were taken at Reynolds numbers ranging from 37 000 to 228 000. Turbulence intensities were in the range of 1.1 to 15.9% while the ratio of integral length scale to leading-edge diameter ranged from 0.05 to 0.30. Stagnation-point velocity gradient was varied by nearly 50%. Stagnation-region heat transfer augmentation was found to increase with decreasing length scale but no optimum length scale was found. Heat transfer augmentation due to turbulence was found to be unaffected by the velocity gradient near the leading edge. A correlation was developed that fit heat transfer data for the square-bar grids to within +/- 4%.

Investigating Some Technical Issues on Cohesive Zone Modeling of Fracture

NASA Technical Reports Server (NTRS)

Wang, John T.

2011-01-01

This study investigates some technical issues related to the use of cohesive zone models (CZMs) in modeling fracture processes. These issues include: why cohesive laws of different shapes can produce similar fracture predictions; under what conditions CZM predictions have a high degree of agreement with linear elastic fracture mechanics (LEFM) analysis results; when the shape of cohesive laws becomes important in the fracture predictions; and why the opening profile along the cohesive zone length needs to be accurately predicted. Two cohesive models were used in this study to address these technical issues. They are the linear softening cohesive model and the Dugdale perfectly plastic cohesive model. Each cohesive model constitutes five cohesive laws of different maximum tractions. All cohesive laws have the same cohesive work rate (CWR) which is defined by the area under the traction-separation curve. The effects of the maximum traction on the cohesive zone length and the critical remote applied stress are investigated for both models. For a CZM to predict a fracture load similar to that obtained by an LEFM analysis, the cohesive zone length needs to be much smaller than the crack length, which reflects the small scale yielding condition requirement for LEFM analysis to be valid. For large-scale cohesive zone cases, the predicted critical remote applied stresses depend on the shape of cohesive models used and can significantly deviate from LEFM results. Furthermore, this study also reveals the importance of accurately predicting the cohesive zone profile in determining the critical remote applied load.

An enhanced method to determine the Young’s modulus of technical single fibres by means of high resolution digital image correlation

NASA Astrophysics Data System (ADS)

Huether, Jonas; Rupp, Peter; Kohlschreiber, Ina; André Weidenmann, Kay

2018-04-01

To obtain mechanical tensile properties of materials it is customary to equip the specimen directly with a device to measure strain and Young’s modulus correctly and only within the measuring length defined by the standards. Whereas a variety of tools such as extensometers, strain gauges and optical systems are available for specimens on coupon level, no market-ready tools to measure strains of single fibres during single fibre tensile tests are available. Although there is a standard for single fibre testing, the procedures described there are only capable of measuring strains of the whole testing setup rather than the strain of the fibre. Without a direct strain measurement on the specimen, the compliance of the test rig itself influences the determination of the Young’s modulus. This work aims to fill this gap by establishing an enhanced method to measure strains directly on the tested fibre and thus provide accurate values for Young’s modulus. It is demonstrated that by applying and then optically tracking fluorescing polymeric beads on single glass fibres, Young’s modulus is determined directly and with high repeatability, without a need to measure at different measuring lengths or compensating for the system compliance. Employing this method to glass fibres, a Young’s modulus of approximately 82.5 GPa was determined, which is in the range of values obtained by applying a conventional procedure. This enhanced measuring technology achieves high accuracy and repeatability while reducing scatter of the data. It was demonstrated that the fluorescing beads do not affect the fibre properties.

Biochemical basis for the biological clock

NASA Technical Reports Server (NTRS)

Morre, D. James; Chueh, Pin-Ju; Pletcher, Jake; Tang, Xiaoyu; Wu, Lian-Ying; Morre, Dorothy M.

2002-01-01

NADH oxidases at the external surface of plant and animal cells (ECTO-NOX proteins) exhibit stable and recurring patterns of oscillations with potentially clock-related, entrainable, and temperature-compensated period lengths of 24 min. To determine if ECTO-NOX proteins might represent the ultradian time keepers (pacemakers) of the biological clock, COS cells were transfected with cDNAs encoding tNOX proteins having a period length of 22 min or with C575A or C558A cysteine to alanine replacements having period lengths of 36 or 42 min. Here we demonstrate that such transfectants exhibited 22, 36, or 40 to 42 h circadian patterns in the activity of glyceraldehyde-3-phosphate dehydrogenase, a common clock-regulated protein, in addition to the endogenous 24 h circadian period length. The fact that the expression of a single oscillatory ECTO-NOX protein determines the period length of a circadian biochemical marker (60 X the ECTO-NOX period length) provides compelling evidence that ECTO-NOX proteins are the biochemical ultradian drivers of the cellular biological clock.

Required length of guardrails before hazards.

PubMed

Tomasch, E; Sinz, W; Hoschopf, H; Gobald, M; Steffan, H; Nadler, B; Nadler, F; Strnad, B; Schneider, F

2011-11-01

One way to protect against impacts during run-off-road accidents with infrastructure is the use of guardrails. However, real-world accidents indicate that vehicles can leave the road and end up behind the guardrail. These vehicles have no possibility of returning to the lane. Vehicles often end up behind the guardrail because the length of the guardrails installed before hazards is too short; this can lead to a collision with a shielded hazard. To identify the basic speed for determining the necessary length of guardrails, we analyzed the speed at which vehicles leave the roadway from the ZEDATU (Zentrale Datenbank Tödlicher Unfälle) real-world accidents database. The required length of guardrail was considered the length that reduces vehicle speed at a maximum theoretically possible deceleration of 0.3g behind the barrier based on real-world road departure speed. To determine the desired length of a guardrail ahead of a hazard, we developed a relationship between guardrail length and the speed at which vehicles depart the roadway. If the initial elements are flared away from the carriageway, the required length will be reduced by up to an additional 30% The ZEDATU database analysis showed that extending the current length of guardrails to the evaluated required length would reduce the number of fatalities among occupants of vehicles striking bridge abutments by approximately eight percent. Copyright © 2011 Elsevier Ltd. All rights reserved.

An image-based method to measure all-terrain vehicle dimensions for engineering safety purposes.

PubMed

Jennissen, Charles A; Miller, Nathan S; Tang, Kaiyang; Denning, Gerene M

2014-04-01

All-terrain vehicle (ATV) crashes are a serious public health and safety concern. Engineering approaches that address ATV injury prevention are critically needed. Avenues to pursue include evidence-based seat design that decreases risky behaviours, such as carrying passengers and operation of adult-size vehicles by children. The goal of this study was to create and validate an image-based method to measure ATV seat length and placement. Publicly available ATV images were downloaded. Adobe Photoshop was then used to generate a vertical grid through the centre of the vehicle, to define the grid scale using the manufacturer's reported wheelbase, and to determine seat length and placement relative to the front and rear axles using this scale. Images that yielded a difference greater than 5% between the calculated and the manufacturer's reported ATV lengths were excluded from further analysis. For the 77 images that met inclusion criteria, the mean±SD for the difference in calculated versus reported vehicle length was 1.8%±1.2%. The Pearson correlation coefficient for comparing image-based seat lengths determined by two independent measurers (20 models) and image-based lengths versus lengths measured at dealerships (12 models) were 0.95 and 0.96, respectively. The image-based method provides accurate and reproducible results for determining ATV measurements, including seat length and placement. This method greatly expands the number of ATV models that can be studied, and may be generalisable to other motor vehicle types. These measurements can be used to guide engineering approaches that improve ATV safety design.

New theory of stellar convection without the mixing-length parameter: new stellar atmosphere model

NASA Astrophysics Data System (ADS)

Pasetto, Stefano; Chiosi, Cesare; Cropper, Mark; Grebel, Eva K.

2018-01-01

Stellar convection is usually described by the mixing-length theory, which makes use of the mixing-length scale factor to express the convective flux, velocity, and temperature gradients of the convective elements and stellar medium. The mixing-length scale is proportional to the local pressure scale height of the star, and the proportionality factor (i.e. mixing-length parameter) is determined by comparing the stellar models to some calibrator, i.e. the Sun. No strong arguments exist to suggest that the mixing-length parameter is the same in all stars and all evolutionary phases and because of this, all stellar models in the literature are hampered by this basic uncertainty. In a recent paper [1] we presented a new theory that does not require the mixing length parameter. Our self-consistent analytical formulation of stellar convection determines all the properties of stellar convection as a function of the physical behavior of the convective elements themselves and the surrounding medium. The new theory of stellar convection is formulated starting from a conventional solution of the Navier-Stokes/Euler equations expressed in a non-inertial reference frame co-moving with the convective elements. The motion of stellar convective cells inside convective-unstable layers is fully determined by a new system of equations for convection in a non-local and time-dependent formalism. The predictions of the new theory are compared with those from the standard mixing-length paradigm with positive results for atmosphere models of the Sun and all the stars in the Hertzsprung-Russell diagram.

Type-inversion as a working mechanism of high voltage MAPbBr3(Cl)-based halide perovskite solar cells.

PubMed

Kedem, Nir; Kulbak, Michael; Brenner, Thomas M; Hodes, Gary; Cahen, David

2017-02-22

Using several metals with different work functions as solar cell back contact we identify majority carrier type inversion in methylammonium lead bromide (MAPbBr3, without intentional doping) as the basis for the formation of a p-n junction. MAPbBr 3 films deposited on TiO 2 are slightly n-type, whereas in a full device they are strongly p-type. The charge transfer between the metal electrode and the halide perovskite (HaP) film is shown to determine the dominant charge carrier type of the HaP and, thus, also of the final cells. Usage of Pt, Au and Pb as metal electrodes shows the effects of metal work function on minority carrier diffusion length and majority carrier concentration in the HaP, as well as on built-in voltage, band bending, and open circuit voltage (V OC ) within a solar cell. V OC > 1.5 V is demonstrated. The higher the metal WF, the higher the carrier concentration induced in the HaP, as indicated by a narrower space charge region and a smaller minority carrier diffusion length. From the analysis of bias-dependent electron beam-induced currents, the HaP carrier concentrations are estimated to be ∼ 1 × 10 17 cm -3 with Au and 2-3 × 10 18 cm -3 with Pt. A model in which type-inversion stretches across the entire film width implies formation of the p-n junction away from the interface, near the back-contact metal electrode. This work highlights the importance of the contact metal on device performance in that contact engineering can also serve to control the carrier concentration in HaP.

Shoot Development and Extension of Quercus serrata Saplings in Response to Insect Damage and Nutrient Conditions

PubMed Central

MIZUMACHI, ERI; MORI, AKIRA; OSAWA, NAOYA; AKIYAMA, REIKO; TOKUCHI, NAOKO

2006-01-01

• Background and Aims Plants have the ability to compensate for damage caused by herbivores. This is important to plant growth, because a plant cannot always avoid damage, even if it has developed defence mechanisms against herbivores. In previous work, we elucidated the herbivory-induced compensatory response of Quercus (at both the individual shoot and whole sapling levels) in both low- and high-nutrient conditions throughout one growing season. In this study, we determine how the compensatory growth of Quercus serrata saplings is achieved at different nutrient levels. • Methods Quercus serrata saplings were grown under controlled conditions. Length, number of leaves and percentage of leaf area lost on all extension units (EUs) were measured. • Key Results Both the probability of flushing and the length of subsequent EUs significantly increased with an increase in the length of the parent EU. The probability of flushing increased with an increase in leaf damage of the parent EU, but the length of subsequent EUs decreased. This indicates that EU growth is fundamentally regulated at the individual EU level. The probabilities of a second and third flush were significantly higher in plants in high-nutrient soil than those in low-nutrient soil. The subsequent EUs of damaged saplings were also significantly longer at high-nutrient conditions. • Conclusions An increase in the probability of flushes in response to herbivore damage is important for damaged saplings to produce new EUs; further, shortening the length of EUs helps to effectively reproduce foliage lost by herbivory. The probability of flushing also varied according to soil nutrient levels, suggesting that the compensatory growth of individual EUs in response to local damage levels is affected by the nutrients available to the whole sapling. PMID:16709576

Parameter estimation of extended free-burning electric arc within 1 kA

NASA Astrophysics Data System (ADS)

Sun, Qiuqin; Liu, Hao; Wang, Feng; Chen, She; Zhai, Yujia

2018-05-01

A long electric arc, as a common phenomenon in the power system, not only damages the electrical equipment but also threatens the safety of the system. In this work, a series of tests on a long electric arc in free air have been conducted. The arc voltage and current data were obtained, and the arc trajectories were captured using a high speed camera. The arc images were digitally processed by means of edge detection, and the length is formulated and achieved. Based on the experimental data, the characteristics of the long arc are discussed. It shows that the arc voltage waveform is close to the square wave with high-frequency components, whereas the current is almost sinusoidal. As the arc length elongates, the arc voltage and the resistance increase sharply. The arc takes a spiral shape with the effect of magnetic forces. The arc length will shorten briefly with the occurrence of the short-circuit phenomenon. Based on the classical Mayr model, the parameters of the long electric arc, including voltage gradient and time constant, with different lengths and current amplitudes are estimated using the linear least-square method. To reduce the computational error, segmentation interpolation is also employed. The results show that the voltage gradient of the long arc is mainly determined by the current amplitude but almost independent of the arc length. However, the time constant is jointly governed by these two variables. The voltage gradient of the arc with the current amplitude at 200-800 A is in the range of 3.9 V/cm-20 V/cm, and the voltage gradient decreases with the increase in current.

Impact of polymer film thickness and cavity size on polymer flow during embossing : towards process design rules for nanoimprint lithography.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schunk, Peter Randall; King, William P.; Sun, Amy Cha-Tien

2006-08-01

This paper presents continuum simulations of polymer flow during nanoimprint lithography (NIL). The simulations capture the underlying physics of polymer flow from the nanometer to millimeter length scale and examine geometry and thermophysical process quantities affecting cavity filling. Variations in embossing tool geometry and polymer film thickness during viscous flow distinguish different flow driving mechanisms. Three parameters can predict polymer deformation mode: cavity width to polymer thickness ratio, polymer supply ratio, and Capillary number. The ratio of cavity width to initial polymer film thickness determines vertically or laterally dominant deformation. The ratio of indenter width to residual film thickness measuresmore » polymer supply beneath the indenter which determines Stokes or squeeze flow. The local geometry ratios can predict a fill time based on laminar flow between plates, Stokes flow, or squeeze flow. Characteristic NIL capillary number based on geometry-dependent fill time distinguishes between capillary or viscous driven flows. The three parameters predict filling modes observed in published studies of NIL deformation over nanometer to millimeter length scales. The work seeks to establish process design rules for NIL and to provide tools for the rational design of NIL master templates, resist polymers, and process parameters.« less

AC signal characterization for optimization of a CMOS single-electron pump

NASA Astrophysics Data System (ADS)

Murray, Roy; Perron, Justin K.; Stewart, M. D., Jr.; Zimmerman, Neil M.

2018-02-01

Pumping single electrons at a set rate is being widely pursued as an electrical current standard. Semiconductor charge pumps have been pursued in a variety of modes, including single gate ratchet, a variety of 2-gate ratchet pumps, and 2-gate turnstiles. Whether pumping with one or two AC signals, lower error rates can result from better knowledge of the properties of the AC signal at the device. In this work, we operated a CMOS single-electron pump with a 2-gate ratchet style measurement and used the results to characterize and optimize our two AC signals. Fitting this data at various frequencies revealed both a difference in signal path length and attenuation between our two AC lines. Using this data, we corrected for the difference in signal path length and attenuation by applying an offset in both the phase and the amplitude at the signal generator. Operating the device as a turnstile while using the optimized parameters determined from the 2-gate ratchet measurement led to much flatter, more robust charge pumping plateaus. This method was useful in tuning our device up for optimal charge pumping, and may prove useful to the semiconductor quantum dot community to determine signal attenuation and path differences at the device.

Resonant acoustic measurement of vapor phase transport phenomenon in porous media

NASA Astrophysics Data System (ADS)

Schuhmann, Richard; Garrett, Steven

2002-05-01

Diffusion of gases through porous media is commonly described using Fick's law and is characterized by a gas diffusion coefficient modified by a media-specific tortuosity parameter. A phase-locked-loop resonance frequency tracker [J. Acoust. Soc. Am. 108, 2520 (2000)] has been upgraded with an insulated copper resonator and a bellows-sealed piston instrumented with an accelerometer. Average system stability (temperature divided by frequency squared) is about 180 ppm. Glass-bead-filled cores of different lengths are fitted into an o-ring sealed opening at the top of the resonator. The rate at which the tracer gas is replaced by air within the resonator is controlled by the core's diffusion constant. Mean molecular weight of the gas mixture in the resonator is determined in real time from the ratio of the absolute temperature to the square of the fundamental acoustic resonance frequency. Molecular weight of the gas mixture is determined approximately six times per minute. Changes in the gas mixture concentration are exponential in time (within 0.1%) over nearly two decades in concentration. We will report diffusion constants for two different sizes of glass beads, in samples of five different lengths, using two different tracer gases, to establish the validity of this approach. [Work supported by ONR.

42 CFR 402.208 - Factors considered in determining whether to exclude, and the length of exclusion.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 2 2014-10-01 2014-10-01 false Factors considered in determining whether to exclude, and the length of exclusion. 402.208 Section 402.208 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CIVIL MONEY PENALTIES...

RVUs poorly correlate with measures of surgical effort and complexity

PubMed Central

Shah, Dhruvil R.; Bold, Richard J.; Yang, Anthony D.; Khatri, Vijay P.; Martinez, Steve R.; Canter, Robert J.

2014-01-01

Background The relationship between procedural relative value units (RVUs) for surgical procedures and other measures of surgeon effort are poorly characterized. We hypothesized that RVUs would poorly correlate with quantifiable metrics of surgeon effort. Methods Using the 2010 ACS-NSQIP database, we selected 11 primary CPT codes associated with high volume surgical procedures. We then identified all patients with a single reported procedural RVU who underwent non-emergent, inpatient general surgical operations. We used linear regression to correlate length of stay, operative time, overall morbidity, frequency of serious adverse events (SAEs), and mortality with RVUs. We used multivariable logistic regression using all pre-operative NSQIP variables to determine other significant predictors of our outcome measures. Results Among 14,481 patients, RVUs poorly correlated with individual length of stay (R2=0.05), operative time (R2=0.10), and mortality (R2=0.35). There was a moderate correlation between RVUs and SAEs (R2 =0.79), and RVUs and overall morbidity (R2=0.75). However, among low to mid-level RVU procedures (11 to 35) there was a poor correlation between SAEs (R2=0.15), overall morbidity (R2=0.05), and RVUs. On multivariable analysis, RVUs were significant predictors of operative time, length of stay, and SAEs (OR 1.06, 95%CI: 1.05–1.07), but RVUs were not a significant predictor of mortality (OR 1.02, 95%CI: 0.99–1.05) Conclusion For common, index general surgery procedures, the current RVU assignments poorly correlate with certain metrics of surgeon work, while moderately correlating with others. Given the increasing emphasis on measuring and tracking surgeon productivity, more objective measures of surgeon work and productivity should be developed. PMID:24953983

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work.

PubMed

Liira, Juha; Verbeek, Jos H; Costa, Giovanni; Driscoll, Tim R; Sallinen, Mikael; Isotalo, Leena K; Ruotsalainen, Jani H

2015-02-01

Shift work results in sleep-wake disturbances, which cause sleepiness during night shifts and reduce sleep length and quality in daytime sleep after the night shift. In its serious form it is also called shift work sleep disorder. Various pharmacological products are used to ameliorate symptoms of sleepiness or poor sleep length and quality. To evaluate the effects of pharmacological interventions to reduce sleepiness or to improve alertness at work and decrease sleep disturbances whilst of work, or both, in workers undertaking shift work. We searched CENTRAL, MEDLINE, EMBASE, PubMed and PsycINFO up to 20 September 2013 and ClinicalTrials.gov up to July 2013. We also screened reference lists of included trials and relevant reviews. We included all eligible randomised controlled trials (RCTs), including cross-over RCTs, of pharmacological products among workers who were engaged in shift work (including night shifts) in their present jobs and who may or may not have had sleep problems. Primary outcomes were sleep length and sleep quality while of work, alertness and sleepiness, or fatigue at work. Two authors independently selected studies, extracted data and assessed risk of bias in included trials. We performed meta-analyses where appropriate. We included 15 randomised placebo-controlled trials with 718 participants. Nine trials evaluated the effect of melatonin and two the effect of hypnotics for improving sleep problems. One trial assessed the effect of modafinil, two of armodafinil and one examined caffeine plus naps to decrease sleepiness or to increase alertness.

Maternal telomere length inheritance in the king penguin.

PubMed

Reichert, S; Rojas, E R; Zahn, S; Robin, J-P; Criscuolo, F; Massemin, S

2015-01-01

Telomeres are emerging as a biomarker for ageing and survival, and are likely important in shaping life-history trade-offs. In particular, telomere length with which one starts in life has been linked to lifelong survival, suggesting that early telomere dynamics are somehow related to life-history trajectories. This result highlights the importance of determining the extent to which telomere length is inherited, as a crucial factor determining early life telomere length. Given the scarcity of species for which telomere length inheritance has been studied, it is pressing to assess the generality of telomere length inheritance patterns. Further, information on how this pattern changes over the course of growth in individuals living under natural conditions should provide some insight on the extent to which environmental constraints also shape telomere dynamics. To fill this gap partly, we followed telomere inheritance in a population of king penguins (Aptenodytes patagonicus). We tested for paternal and maternal influence on chick initial telomere length (10 days old after hatching), and how these relationships changed with chick age (at 70, 200 and 300 days old). Based on a correlative approach, offspring telomere length was positively associated with maternal telomere length early in life (at 10 days old). However, this relationship was not significant at older ages. These data suggest that telomere length in birds is maternally inherited. Nonetheless, the influence of environmental conditions during growth remained an important factor shaping telomere length, as the maternal link disappeared with chicks' age.

Tracheid length prediction in Pinus palustris by means of near infrared spectroscopy: the influence of age

Treesearch

Brian K. Via; Todd F. Shupe; Michael Stine; Chi-Leung So; Leslie H. Groom

2005-01-01

The predidion of tracheid Length using near infrared (NIR) wavelengths can provide either useful or misleading calibrations depending on the context. This can happen since tracheid length is not directly related to the absorbance at any wavelength but is instead the result of a seondary correlation with some unknown chemical constituent. In this work, the effect of...

Root Architecture Diversity and Meristem Dynamics in Different Populations of Arabidopsis thaliana

PubMed Central

Aceves-García, Pamela; Álvarez-Buylla, Elena R.; Garay-Arroyo, Adriana; García-Ponce, Berenice; Muñoz, Rodrigo; Sánchez, María de la Paz

2016-01-01

Arabidopsis thaliana has been an excellent model system for molecular genetic approaches to development and physiology. More recently, the potential of studying various accessions collected from diverse habitats has been started to exploit. Col-0 has been the best-studied accession but we now know that several traits show significant divergences among them. In this work, we focused in the root that has become a key system for development. We studied root architecture and growth dynamics of 12 Arabidopsis accessions. Our data reveal a wide variability in root architecture and root length among accessions. We also found variability in the root apical meristem (RAM), explained mainly by cell size at the RAM transition domain and possibly by peculiar forms of organization at the stem cell niche in some accessions. Contrary to Col-0 reports, in some accessions the RAM size not always explains the variations in the root length; indicating that elongated cell size could be more relevant in the determination of root length than the RAM size itself. This study contributes to investigations dealing with understanding the molecular and cellular basis of phenotypic variation, the role of plasticity on adaptation, and the developmental mechanisms that may restrict phenotypic variation in response to contrasting environmental conditions. PMID:27379140

Root Architecture Diversity and Meristem Dynamics in Different Populations of Arabidopsis thaliana.

PubMed

Aceves-García, Pamela; Álvarez-Buylla, Elena R; Garay-Arroyo, Adriana; García-Ponce, Berenice; Muñoz, Rodrigo; Sánchez, María de la Paz

2016-01-01

Arabidopsis thaliana has been an excellent model system for molecular genetic approaches to development and physiology. More recently, the potential of studying various accessions collected from diverse habitats has been started to exploit. Col-0 has been the best-studied accession but we now know that several traits show significant divergences among them. In this work, we focused in the root that has become a key system for development. We studied root architecture and growth dynamics of 12 Arabidopsis accessions. Our data reveal a wide variability in root architecture and root length among accessions. We also found variability in the root apical meristem (RAM), explained mainly by cell size at the RAM transition domain and possibly by peculiar forms of organization at the stem cell niche in some accessions. Contrary to Col-0 reports, in some accessions the RAM size not always explains the variations in the root length; indicating that elongated cell size could be more relevant in the determination of root length than the RAM size itself. This study contributes to investigations dealing with understanding the molecular and cellular basis of phenotypic variation, the role of plasticity on adaptation, and the developmental mechanisms that may restrict phenotypic variation in response to contrasting environmental conditions.

The energetics of tightly bent DNA: a composite elastica model including local melting

NASA Astrophysics Data System (ADS)

Evans, Arthur; Levine, Alex

2012-02-01

Melting transitions are well-known to be affected by the application of mechanical stress. Motivated by the experiments of Zocchi and collaborators (Qu and Zocchi 2011, EPL 94 18003), we explore the effect of the application of mechanical stress on DNA melting in a particular composite of a stiff double stranded piece of DNA (dsDNA), shorter than its own persistence length, whose ends are linked by a flexible single stranded piece of DNA (ssDNA). The flexible ssDNA acts as a Gaussian polymer coil bending the stiff dsDNA through an elastic force that is controllable by the length of the ssDNA chain. In this talk we present theoretical predictions for two experimentally accessible features: the degree of local dsDNA melting and the local elastic energy of the dsDNA/ssDNA construct both as a function of the length of the attached ssDNA. We also address the effect of introducing a nick (broken covalent bond) in the dsDNA backbone on these results and discuss the implications of such data on the relative importance of backbone elasticity versus base stacking and base pairing interactions in determining the elasticity of dsDNA. This work also addresses open questions in the nonlinear elasticity of DNA in tightly bent curves.

Physical soil properties and slope treatments effects on hydraulic excavator productivity for forest road construction.

PubMed

Parsakho, Aidin; Hosseini, Seyed Ataollah; Jalilvand, Hamid; Lotfalian, Majid

2008-06-01

Effects of moisture, porosity and soil bulk density properties, grubbing time and terrain side slopes on pc 220 komatsu hydraulic excavator productivity were investigated in Miana forests road construction project which located in the northern forest of Iran. Soil moisture and porosity determined by samples were taken from undisturbed soil. The elements of daily works were measured with a digital stop watch and video camera in 14 observations (days). The road length and cross section profiles after each 20 m were selected to estimate earthworks volume. Results showed that the mean production rates for the pc 220 komatsu excavators were 60.13 m3 h(-1) and earthwork 14.76 m h(-1) when the mean depth of excavation or cutting was 4.27 m3 m(-1), respectively. There was no significant effects (p = 0.5288) from the slope classes' treatments on productivity, whereas grubbing time, soil moisture, bulk density and porosity had significantly affected on excavator earthworks volume (p < 0.0001). Clear difference was showed between the earthwork length by slope classes (p = 0.0060). Grubbing time (p = 0.2180), soil moisture (p = 0.1622), bulk density (p = 0.2490) and porosity (p = 0.2159) had no significant effect on the excavator earthworks length.

The influence of economic business cycles on United States suicide rates.

PubMed

Wasserman, I M

1984-01-01

A number of social science investigators have shown that a downturn in the economy leads to an increase in the suicide rate. However, the previous works on the subject are flawed by the fact that they employ years as their temporal unit of analysis. This time period is so large that it makes it difficult for investigators to precisely determine the length of the lag effect, while at the same time removing the autocorrelation effects. Also, although most works on suicide and the business cycle employ unemployment as a measure of a downturn in the business cycle, the average duration of unemployment represents a better measure for determining the social impact of an economic downturn. From 1947 to 1977 the average monthly duration of unemployment is statistically related to the suicide rate using multivariate time-series analysis. From 1910 to 1939 the Ayres business index, a surrogate measure for movement in the business cycle, is statistically related to the monthly suicide rate. An examination of the findings confirms that in most cases a downturn in the economy causes an increase in the suicide rate.

Approximate sample sizes required to estimate length distributions

USGS Publications Warehouse

Miranda, L.E.

2007-01-01

The sample sizes required to estimate fish length were determined by bootstrapping from reference length distributions. Depending on population characteristics and species-specific maximum lengths, 1-cm length-frequency histograms required 375-1,200 fish to estimate within 10% with 80% confidence, 2.5-cm histograms required 150-425 fish, proportional stock density required 75-140 fish, and mean length required 75-160 fish. In general, smaller species, smaller populations, populations with higher mortality, and simpler length statistics required fewer samples. Indices that require low sample sizes may be suitable for monitoring population status, and when large changes in length are evident, additional sampling effort may be allocated to more precisely define length status with more informative estimators. ?? Copyright by the American Fisheries Society 2007.

Validity of plant fiber length measurement : a review of fiber length measurement based on kenaf as a model

Treesearch

James S. Han; Theodore Mianowski; Yi-yu Lin

1999-01-01

The efficacy of fiber length measurement techniques such as digitizing, the Kajaani procedure, and NIH Image are compared in order to determine the optimal tool. Kenaf bast fibers, aspen, and red pine fibers were collected from different anatomical parts, and the fiber lengths were compared using various analytical tools. A statistical analysis on the validity of the...

On the number of multiplications necessary to compute a length-2 exp n DFT

NASA Technical Reports Server (NTRS)

Heideman, M. T.; Burrus, C. S.

1986-01-01

The number of multiplications necessary and sufficient to compute a length-2 exp n DFT is determined. The method of derivation is shown to apply to the multiplicative complexity results of Winograd (1980, 1981) for a length-p exp n DFT, for p an odd prime number. The multiplicative complexity of the one-dimensional DFT is summarized for many possible lengths.

30 CFR 1206.102 - How do I calculate royalty value for oil that I or my affiliate sell(s) under an arm's-length...

Code of Federal Regulations, 2012 CFR

2012-07-01

... or my affiliate sell(s) under an arm's-length contract? 1206.102 Section 1206.102 Mineral Resources...) under an arm's-length contract? (a) The value of oil under this section is the gross proceeds accruing to the seller under the arm's-length contract, less applicable allowances determined under § 1206.110...

30 CFR 1206.102 - How do I calculate royalty value for oil that I or my affiliate sell(s) under an arm's-length...

Code of Federal Regulations, 2013 CFR

2013-07-01

... or my affiliate sell(s) under an arm's-length contract? 1206.102 Section 1206.102 Mineral Resources...) under an arm's-length contract? (a) The value of oil under this section is the gross proceeds accruing to the seller under the arm's-length contract, less applicable allowances determined under § 1206.110...

30 CFR 1206.102 - How do I calculate royalty value for oil that I or my affiliate sell(s) under an arm's-length...

Code of Federal Regulations, 2014 CFR

2014-07-01

... or my affiliate sell(s) under an arm's-length contract? 1206.102 Section 1206.102 Mineral Resources...) under an arm's-length contract? (a) The value of oil under this section is the gross proceeds accruing to the seller under the arm's-length contract, less applicable allowances determined under § 1206.110...

30 CFR 1206.102 - How do I calculate royalty value for oil that I or my affiliate sell(s) under an arm's-length...

Code of Federal Regulations, 2011 CFR

2011-07-01

... or my affiliate sell(s) under an arm's-length contract? 1206.102 Section 1206.102 Mineral Resources... affiliate sell(s) under an arm's-length contract? (a) The value of oil under this section is the gross proceeds accruing to the seller under the arm's-length contract, less applicable allowances determined...

Transport Imaging of Multi-Junction and CIGS Solar Cell Materials

DTIC Science & Technology

2011-12-01

solar cells start with the material charge transport parameters, namely the charge mobility, lifetime and diffusion length . It is the goal of...every solar cell manufacturer to maintain high carrier lifetime so as to realize long diffusion lengths . Long diffusion lengths ensure that the charges...Thus, being able to accurately determine the diffusion length of any solar cell material proves advantageous by providing insights

Ultrasound biomicroscopy for determining visian implantable contact lens length in phakic IOL implantation.

PubMed

Choi, Ki Hwan; Chung, Song Ee; Chung, Tae Young; Chung, Eui Sang

2007-04-01

To assess the efficacy of the ultrasound biomicroscopic (UBM) method in estimating the sulcus-to-sulcus horizontal diameter for Visian Implantable Contact Lens (ICL, model V4) length determination to obtain optimal ICL vault. The results of postoperative ICL vaults in 30 eyes of 18 patients were retrospectively analyzed. In 17 eyes, ICL length was determined using the conventional method, and in 13 eyes, ICL length was determined using the UBM method. The UBM method was carried out by measuring the sulcus to limbus distance on each side by 50 MHz UBM and adding the white-to-white diameter by caliper or Orbscan. The ICL vaults were measured using the UBM method at 1 and 6 months postoperatively and the results were compared between the two groups. Ideal ICL vault was defined as vault between 250 and 750 microm. The relation between the ICL vault, footplate location, and ICL power was also investigated. In the UBM method group, ICL vault was within the ideal range in all 13 (100%) eyes at 1 and 6 months postoperatively, whereas in the conventional method group, 10 (58.8%) eyes showed ideal vault at 1 month postoperatively (P = .01) and 9 (52.9%) eyes showed ideal vault at 6 months postoperatively (P < .01). The ideal ICL footplate location was achieved in the ciliary sulcus in 11 (84.6%) eyes of the UBM method group and 10 (64.7%) eyes of the conventional method group. However, the differences between the two groups were not statistically significant. The ICL vault was not significantly affected by the ICL power. Implantable Contact Lens length determined by the UBM method achieved significantly more ideal ICL vault than that of the conventional white-to-white method. The UBM method is superior to the conventional method in terms of predicting the sulcus-to-sulcus horizontal diameter for ICL length determination.

An investigation into preserving spatially-distinct pore systems in multi-component rocks using a fossiliferous limestone example

NASA Astrophysics Data System (ADS)

Jiang, Zeyun; Couples, Gary D.; Lewis, Helen; Mangione, Alessandro

2018-07-01

Limestones containing abundant disc-shaped fossil Nummulites can form significant hydrocarbon reservoirs but they have a distinctly heterogeneous distribution of pore shapes, sizes and connectivities, which make it particularly difficult to calculate petrophysical properties and consequent flow outcomes. The severity of the problem rests on the wide length-scale range from the millimetre scale of the fossil's pore space to the micron scale of rock matrix pores. This work develops a technique to incorporate multi-scale void systems into a pore network, which is used to calculate the petrophysical properties for subsequent flow simulations at different stages in the limestone's petrophysical evolution. While rock pore size, shape and connectivity can be determined, with varying levels of fidelity, using techniques such as X-ray computed tomography (CT) or scanning electron microscopy (SEM), this work represents a more challenging class where the rock of interest is insufficiently sampled or, as here, has been overprinted by extensive chemical diagenesis. The main challenge is integrating multi-scale void structures derived from both SEM and CT images, into a single model or a pore-scale network while still honouring the nature of the connections across these length scales. Pore network flow simulations are used to illustrate the technique but of equal importance, to demonstrate how supportable earlier-stage petrophysical property distributions can be used to assess the viability of several potential geological event sequences. The results of our flow simulations on generated models highlight the requirement for correct determination of the dominant pore scales (one plus of nm, μm, mm, cm), the spatial correlation and the cross-scale connections.

Computation of the effective mechanical response of biological networks accounting for large configuration changes.

PubMed

El Nady, K; Ganghoffer, J F

2016-05-01

The asymptotic homogenization technique is involved to derive the effective elastic response of biological membranes viewed as repetitive beam networks. Thereby, a systematic methodology is established, allowing the prediction of the overall mechanical properties of biological membranes in the nonlinear regime, reflecting the influence of the geometrical and mechanical micro-parameters of the network structure on the overall response of the equivalent continuum. Biomembranes networks are classified based on nodal connectivity, so that we analyze in this work 3, 4 and 6-connectivity networks, which are representative of most biological networks. The individual filaments of the network are described as undulated beams prone to entropic elasticity, with tensile moduli determined from their persistence length. The effective micropolar continuum evaluated as a continuum substitute of the biological network has a kinematics reflecting the discrete network deformation modes, involving a nodal displacement and a microrotation. The statics involves the classical Cauchy stress and internal moments encapsulated into couple stresses, which develop internal work in duality to microcurvatures reflecting local network undulations. The relative ratio of the characteristic bending length of the effective micropolar continuum to the unit cell size determines the relevant choice of the equivalent medium. In most cases, the Cauchy continuum is sufficient to model biomembranes. The peptidoglycan network may exhibit a re-entrant hexagonal configuration due to thermal or pressure fluctuations, for which micropolar effects become important. The homogenized responses are in good agreement with FE simulations performed over the whole network. The predictive nature of the employed homogenization technique allows the identification of a strain energy density of a hyperelastic model, for the purpose of performing structural calculations of the shape evolutions of biomembranes. Copyright © 2015 Elsevier Ltd. All rights reserved.

Effect of Chamber Backpressure on Swirl Injector Fluid Mechanics

NASA Technical Reports Server (NTRS)

Kenny, R. Jeremy; Hulka, James R.; Moser, Marlow D.; Rhys, Noah O.

2008-01-01

A common propellant combination used for high thrust generation is GH2/LOX. Historical GH2/LOX injection elements have been of the shear-coaxial type. Element type has a large heritage of research work to aid in element design. The swirl-coaxial element, despite its many performance benefits, has a relatively small amount of historical, LRE-oriented work to draw from. Design features of interest are grounded in the fluid mechanics of the liquid swirl process itself, are based on data from low-pressure, low mass flow rate experiments. There is a need to investigate how high ambient pressures and mass flow rates influence internal and external swirl features. The objective of this research is to determine influence of varying liquid mass flow rate and ambient chamber pressure on the intact-length fluid mechanics of a liquid swirl element.

Policy Building Blocks: Helping Policymakers Determine Policy Staging for the Development of Distributed PV Markets: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doris, E.

2012-04-01

There is a growing body of qualitative and a limited body of quantitative literature supporting the common assertion that policy drives development of clean energy resources. Recent work in this area indicates that the impact of policy depends on policy type, length of time in place, and economic and social contexts of implementation. This work aims to inform policymakers about the impact of different policy types and to assist in the staging of those policies to maximize individual policy effectiveness and development of the market. To do so, this paper provides a framework for policy development to support the marketmore » for distributed photovoltaic systems. Next steps include mathematical validation of the framework and development of specific policy pathways given state economic and resource contexts.« less

Two-Dimensional Optical CDMA System Parameters Limitations for Wavelength Hopping/Time-Spreading Scheme based on Simulation Experiment

NASA Astrophysics Data System (ADS)

Kandouci, Chahinaz; Djebbari, Ali

2018-04-01

A new family of two-dimensional optical hybrid code which employs zero cross-correlation (ZCC) codes, constructed by the balanced incomplete block design BIBD, as both time-spreading and wavelength hopping patterns are used in this paper. The obtained codes have both off-peak autocorrelation and cross-correlation values respectively equal to zero and unity. The work in this paper is a computer experiment performed using Optisystem 9.0 software program as a simulator to determine the wavelength hopping/time spreading (WH/TS) OCDMA system performances limitations. Five system parameters were considered in this work: the optical fiber length (transmission distance), the bitrate, the chip spacing and the transmitted power. This paper shows for what sufficient system performance parameters (BER≤10-9, Q≥6) the system can stand for.

Creation of a predictive equation to estimate fat-free mass and the ratio of fat-free mass to skeletal size using morphometry in lean working farm dogs.

PubMed

Leung, Y M; Cave, N J; Hodgson, B A S

2018-06-27

To develop an equation that accurately estimates fat-free mass (FFM) and the ratio of FFM to skeletal size or mass, using morphometric measurements in lean working farm dogs, and to examine the association between FFM derived from body condition score (BCS) and FFM measured using isotope dilution. Thirteen Huntaway and seven Heading working dogs from sheep and beef farms in the Waikato region of New Zealand were recruited based on BCS (BCS <3, 3-4, >4) using a nine-point scale. Bodyweight, BCS, and morphometric measurements (head length and circumference, body length, thoracic girth, and fore and hind limb length) were recorded for each dog, and body composition was measured using an isotopic dilution technique. A new variable using morphometric measurements, termed skeletal size, was created using principal component analysis. Models for predicting FFM, leanST (FFM minus skeletal mass) and ratios of FFM and leanST to skeletal size or mass were generated using multiple linear regression analysis. Mean FFM of the 20 dogs, measured by isotope dilution, was 22.1 (SD 4.4) kg and the percentage FFM of bodyweight was 87.0 (SD 5.0)%. Median BCS was 3.0 (min 1, max 6). Bodyweight, breed, age and skeletal size or mass were associated with measured FFM (p<0.001). There was a good correlation between predicted FFM and measured FFM (R 2 =0.96), and for the ratio of predicted FFM to skeletal size and measured values (R 2 =0.99). Correlation coefficients were higher for the ratio FFM and leanST to skeletal size than for ratios using skeletal mass. There was a positive correlation between BCS-derived fat mass as a percentage of bodyweight and fat mass percentage determined using isotope dilution (R 2 =0.65). As expected, the predictive equation was accurate in estimating FFM when tested on the same group of dogs used to develop the equation. The significance of breed, independent of skeletal size, in predicting FFM indicates that individual breed formulae may be required. Future studies that apply these equations on a greater population of working Huntaway and Heading dogs are needed to establish the utility of these equations on a large scale. Such studies could ascertain if there is a ratio for lean mass to skeletal size below which the risk of injury or disease increases. If these equations prove useful they would provide an objective and non-invasive measure to determine when welfare in individual dogs is compromised by underfeeding.

Bacterial Polysaccharide Co-Polymerases Share a Common Framework for Control of Polymer Length

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tocilj,A.; Munger, C.; Proteau, A.

2008-01-01

The chain length distribution of complex polysaccharides present on the bacterial surface is determined by polysaccharide co-polymerases (PCPs) anchored in the inner membrane. We report crystal structures of the periplasmic domains of three PCPs that impart substantially different chain length distributions to surface polysaccharides. Despite very low sequence similarities, they have a common protomer structure with a long central alpha-helix extending 100 Angstroms into the periplasm. The protomers self-assemble into bell-shaped oligomers of variable sizes, with a large internal cavity. Electron microscopy shows that one of the full-length PCPs has a similar organization as that observed in the crystal formore » its periplasmic domain alone. Functional studies suggest that the top of the PCP oligomers is an important region for determining polysaccharide modal length. These structures provide a detailed view of components of the bacterial polysaccharide assembly machinery.« less

Early life determinants of frailty in old age: the Helsinki Birth Cohort Study.

PubMed

Haapanen, M J; Perälä, M M; Salonen, M K; Kajantie, E; Simonen, M; Pohjolainen, P; Eriksson, J G; von Bonsdorff, M B

2018-04-12

there is evidence suggesting that several chronic diseases have their origins in utero and that development taking place during sensitive periods may affect the aging process. We investigated whether early life determinants would be associated with frailty in old age. at a mean age of 71 years, 1,078 participants belonging to the Helsinki Birth Cohort Study were assessed for frailty according to the Fried frailty criteria. Early life measurements (birth weight, length, mother body mass index [BMI] and parity) were obtained from birth, child welfare and school health records. Multinomial regression analysis was used to assess the association between early life determinants and frailty in old age. weight, length and BMI at birth were all inversely associated with frailty in old age. A 1 kg increase in birth weight was associated with a lower relative risk ratio (RRR) of frailty (age and sex-adjusted RRR = 0.40, 95% CI: 0.19, 0.82) compared to non-frailty. Associations persisted after adjusting for several confounding factors. Compared to cohort members in the upper middle class, those who as adults worked as manual workers or belonged to the lower middle class, were at an increased risk of frailty. those who were small at birth were at an increased risk of developing frailty in old age, suggesting that frailty is at least partly programmed in early life. A less privileged socioeconomic status in adulthood was associated with an increased risk of frailty in old age.

Visualizing the global secondary structure of a viral RNA genome with cryo-electron microscopy

PubMed Central

Garmann, Rees F.; Gopal, Ajaykumar; Athavale, Shreyas S.; Knobler, Charles M.; Gelbart, William M.; Harvey, Stephen C.

2015-01-01

The lifecycle, and therefore the virulence, of single-stranded (ss)-RNA viruses is regulated not only by their particular protein gene products, but also by the secondary and tertiary structure of their genomes. The secondary structure of the entire genomic RNA of satellite tobacco mosaic virus (STMV) was recently determined by selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE). The SHAPE analysis suggested a single highly extended secondary structure with much less branching than occurs in the ensemble of structures predicted by purely thermodynamic algorithms. Here we examine the solution-equilibrated STMV genome by direct visualization with cryo-electron microscopy (cryo-EM), using an RNA of similar length transcribed from the yeast genome as a control. The cryo-EM data reveal an ensemble of branching patterns that are collectively consistent with the SHAPE-derived secondary structure model. Thus, our results both elucidate the statistical nature of the secondary structure of large ss-RNAs and give visual support for modern RNA structure determination methods. Additionally, this work introduces cryo-EM as a means to distinguish between competing secondary structure models if the models differ significantly in terms of the number and/or length of branches. Furthermore, with the latest advances in cryo-EM technology, we suggest the possibility of developing methods that incorporate restraints from cryo-EM into the next generation of algorithms for the determination of RNA secondary and tertiary structures. PMID:25752599

Otolith Length-Fish Length Relationships of Eleven US Arctic Fish Species and Their Application to Ice Seal Diet Studies

NASA Astrophysics Data System (ADS)

Walker, K. L.; Norcross, B.

2016-02-01

The Arctic ecosystem has moved into the spotlight of scientific research in recent years due to increased climate change and oil and gas exploration. Arctic fishes and Arctic marine mammals represent key parts of this ecosystem, with fish being a common part of ice seal diets in the Arctic. Determining sizes of fish consumed by ice seals is difficult because otoliths are often the only part left of the fish after digestion. Otolith length is known to be positively related to fish length. By developing species-specific otolith-body morphometric relationships for Arctic marine fishes, fish length can be determined for fish prey found in seal stomachs. Fish were collected during ice free months in the Beaufort and Chukchi seas 2009 - 2014, and the most prevalent species captured were chosen for analysis. Otoliths from eleven fish species from seven families were measured. All species had strong linear relationships between otolith length and fish total length. Nine species had coefficient of determination values over 0.75, indicating that most of the variability in the otolith to fish length relationship was explained by the linear regression. These relationships will be applied to otoliths found in stomachs of three species of ice seals (spotted Phoca largha, ringed Pusa hispida, and bearded Erignathus barbatus) and used to estimate fish total length at time of consumption. Fish lengths can in turn be used to calculate fish weight, enabling further investigation into ice seal energetic demands. This application will aid in understanding how ice seals interact with fish communities in the US Arctic and directly contribute to diet comparisons among and within ice seal species. A better understanding of predator-prey interactions in the US Arctic will aid in predicting how ice seal and fish species will adapt to a changing Arctic.

[Experimental study of restiffening of the rigor mortis].

PubMed

Wang, X; Li, M; Liao, Z G; Yi, X F; Peng, X M

2001-11-01

To observe changes of the length of sarcomere of rat when restiffening. We measured the length of sarcomere of quadriceps in 40 rats in different condition by scanning electron microscope. The length of sarcomere of rigor mortis without destroy is obviously shorter than that of restiffening. The length of sarcomere is negatively correlative to the intensity of rigor mortis. Measuring the length of sarcomere can determine the intensity of rigor mortis and provide evidence for estimation of time since death.

Length changes in white sturgeon larvae preserved in ethanol or formaldehyde

USGS Publications Warehouse

Bayer, J.M.; Counihan, T.D.

2001-01-01

We examined the effects of two preservatives on the notochord and total lengths of white sturgeon (Acipenser transmontanus) larvae. White sturgeon larvae that were one, seven, and 14 days old were measured live and then preserved in 95% ethanol or 10% formaldehyde. Length changes were then determined at 20 and 95 days after preservation. We found mean length changes ranging from 0.4% to 3.4% shrinkage. Length changes varied with preservative, age of larvae, and length of time preserved. Constant length correction factors are provided for 10% formaldehyde or 95% ethanol valid for larvae between 1 and 14 days old preserved for less than 100 days.

Polymer Physics Prize Talk

NASA Astrophysics Data System (ADS)

Olvera de La Cruz, Monica

Polymer electrolytes have been particularly difficult to describe theoretically given the large number of disparate length scales involved in determining their physical properties. The Debye length, the Bjerrum length, the ion size, the chain length, and the distance between the charges along their backbones determine their structure and their response to external fields. We have developed an approach that uses multi-scale calculations with the capability of demonstrating the phase behavior of polymer electrolytes and of providing a conceptual understanding of how charge dictates nano-scale structure formation. Moreover, our molecular dynamics simulations have provided an understanding of the coupling of their conformation to their dynamics, which is crucial to design self-assembling materials, as well as to explore the dynamics of complex electrolytes for energy storage and conversion applications.

S-F graphic representation analysis of photoelectric facula focometer poroo-plate glass

NASA Astrophysics Data System (ADS)

Tong, Yilin; Han, Xuecai

2016-10-01

Optical system focal length is usually based on the magnification method with focal length measurement poroo-plate glass is used as base element measuring focal length of focometer. On the basis of using analysis of magnification method to measure the accuracy of optical lens focal length, an expression between the ruling span of poroo-plate glass and the focal length of measured optical system was deduced, an efficient method to work out S-F graph with AUTOCAD was developed, the selecting principle of focometer parameter was analyzed, and Applied examples for designing poroo-plate glass in S-F figure was obtained.

Longer biopsy cores do not increase prostate cancer detection rate: A large-scale cohort study refuting cut-off values indicated in the literature

PubMed Central

Yılmaz, Hasan; Yavuz, Ufuk; Üstüner, Murat; Çiftçi, Seyfettin; Yaşar, Hikmet; Müezzinoğlu, Bahar; Uslubaş, Ali Kemal; Dillioğlugil, Özdal

2017-01-01

Objective Only a few papers in the literature aimed to evaluate biopsy core lengths. Additionally, studies evaluated the core length with different approaches. We aimed to determine whether prostate cancer (PCa) detection is affected from core lengths according to three different approaches in a large standard cohort and compare our cut-off values with the published cut-offs. Material and methods We retrospectively analyzed 1,523 initial consecutive transrectal ultrasound-guided 12-core prostate biopsies. Biopsies were evaluated with respect to total core length (total length of each patients’ core) average core length (total core length divided by total number of cores in each patient), and mean core length (mean length of all cores pooled), and compared our cut-off values with the published cut-offs. The prostate volumes were categorized into four groups (<30, 30–59.99, 60–119.99, ≥120 cm3) and PCa detection rates in these categories were examined. Results PCa was found in 41.5% patients. There was no difference between benign and malignant mean core lengths of the pooled cores (p>0.05). Total core length and average core length were not significantly associated with PCa in multivariate logistic regression analyses (p>0.05). The core lengths (mean, average and total core lengths) increased (p<0.001) and PCa rates decreased (p<0.001) steadily with increasing prostate volume categories. PCa percentages decreased in all categories above the utilized cut-offs for mean (p>0.05), average (p<0.05), and total core lengths (p>0.05). Conclusion There was no difference between mean core lengths of benign and malignant cores. Total core length and average core length were not significantly associated with PCa. Contrary to the cut-offs used for mean and average core lengths in the published studies, PCa rates decrease as these core lengths increase. Larger studies are necessary for the determination and acceptance of accurate cut-offs. PMID:28861301

Thermal spraying of polyethylene-based polymers: Processing and characterization

NASA Astrophysics Data System (ADS)

Otterson, David Mark

This research explores the development of a flame-spray process map as it relates to polymers. This work provides a more complete understanding of the thermal history of the coating material from injection, to deposition and finally to cooling. This was accomplished through precise control of the processing conditions during deposition. Mass flow meters were used to monitor air and fuel flows as they were systematically changed, while temperatures were simultaneously monitored along the length of the flame. A process model was then implemented that incorporated this information along with measured particle velocities, particle size distribution, the polymer's melting temperature and its enthalpy of melting. This computational model was then used to develop a process map that described particle softening, melting and decomposition phenomena as a function of particle size and standoff distance. It demonstrated that changes in particle size caused significant variations in particle states achieved in-flight. A series of experiments were used to determine the range of spray parameters within which a cohesive coating without visible signs of degradation could be sprayed. These results provided additional information that complimented the computational processing map. The boundaries established by these results were the basis for a Statistical Design of Experiments that tested the effects that subtle processing changes had on coating properties. A series of processing maps were developed that combined the computational and the experimental results to describe the manner in which processing parameters interact to determine the degree of melting, polymer degradation and coating porosity. Strong interactions between standoff distance and traverse rate can cause the polymer to degrade and form pores in the coating. A clear picture of the manner in which particle size and standoff distance interact to determine particle melting was provided by combining the computational processing map with the collected splats and microstructures. Finally, a strong interaction was observed between standoff distance and flame length, which is determined by the air:fuel ratio. When flame length exceeds the standoff distance, polymer degradation results from excessive heating of the substrate. A descriptive model of the process is then provided to highlight the importance of these interactions. (Abstract shortened by UMI.)

Determination of Normal Distribution of Distended Colon Volumes to Guide Performance of Colonic Imaging With Fluid Distention.

PubMed

Zheng, Karen S; Small, William C; Mittal, Pardeep K; Cai, Qingpo; Kang, Jian; Moreno, Courtney C

2016-01-01

The purpose was to determine the normal distribution of distended colon volumes as a guide for rectal contrast material administration protocols. All computed tomography colonography studies performed at Emory University Hospital, Atlanta, Georgia, between January 2009 and January 2015, were reviewed retrospectively. In total, 85 subjects were included in the analysis (64% [54 of 85] female and 36% [31 of 85] male). Mean patient age was 65 years (range: 42-86y). Distended colon volumes were determined from colon length and transaxial diameter measurements made using a 3-dimensional workstation. Age, sex, race, height, weight, and body mass index were recorded. The normal distributions of distended colon volumes and lengths were determined. Correlations between colonic volume and colonic length, and demographic variables were assessed. Mean colon volume was 2.1L (range: 0.7-4.4L). Nearly, 17% of patients had a distended colonic volume of >3L. Mean colon length was 197cm (range: 118-285cm). A weak negative correlation was found between age and colonic volume (r = -0.221; P = 0.04). A weak positive correlation was found between body mass index and colonic length (r = 0.368; P = 0.007). Otherwise, no significant correlations were found for distended colonic volume or length and demographic variables. In conclusion, an average of approximately 2L of contrast material may be necessary to achieve full colonic opacification. This volume is larger than previously reported volumes (0.8-1.5L) for rectal contrast material administration protocols. Copyright © 2015 Mosby, Inc. All rights reserved.

FLP-18 Functions through the G-Protein-Coupled Receptors NPR-1 and NPR-4 to Modulate Reversal Length in Caenorhabditis elegans.

PubMed

Bhardwaj, Ashwani; Thapliyal, Saurabh; Dahiya, Yogesh; Babu, Kavita

2018-05-16

Animal behavior is critically dependent on the activity of neuropeptides. Reversals, one of the most conspicuous behaviors in Caenorhabditis elegans , plays an important role in determining the navigation strategy of the animal. Our experiments on hermaphrodite C. elegans show the involvement of a neuropeptide FLP-18 in modulating reversal length in these hermaphrodites. We show that FLP-18 controls the reversal length by regulating the activity of AVA interneurons through the G-protein-coupled neuropeptide receptors, NPR-4 and NPR-1. We go on to show that the site of action of these receptors is the AVA interneuron for NPR-4 and the ASE sensory neurons for NPR-1. We further show that mutants in the neuropeptide, flp-18 , and its receptors show increased reversal lengths. Consistent with the behavioral data, calcium levels in the AVA neuron of freely reversing C. elegans were significantly higher and persisted for longer durations in flp-18 , npr-1 , npr-4 , and npr-1 npr-4 genetic backgrounds compared with wild-type control animals. Finally, we show that increasing FLP-18 levels through genetic and physiological manipulations causes shorter reversal lengths. Together, our analysis suggests that the FLP-18/NPR-1/NPR-4 signaling is a pivotal point in the regulation of reversal length under varied genetic and environmental conditions. SIGNIFICANCE STATEMENT In this study, we elucidate the circuit and molecular machinery required for normal reversal behavior in hermaphrodite Caenorhabditis elegans We delineate the circuit and the neuropeptide receptors required for maintaining reversal length in C. elegans Our work sheds light on the importance of a single neuropeptide, FLP-18, and how change in levels in this one peptide could allow the animal to change the length of its reversal, thereby modulating how the C. elegans explores its environment. We also go on to show that FLP-18 functions to maintain reversal length through the neuropeptide receptors NPR-4 and NPR-1. Our study will allow for a better understanding of the complete repertoire of behaviors shown by freely moving animals as they explore their environment. Copyright © 2018 the authors 0270-6474/18/384641-14$15.00/0.

[Hemoglobin changes (Hb) in miners exposed to high altitude and associated factors].

PubMed

Mejia, Christian R; Quiñones-Laveriano, Dante M; Gomero, Raúl; Pérez-Pérez, Luis

To determine the variation of hemoglobin (Hb) in two groups of miners working at different altitudes. A longitudinal study conducted in a private company. Hb was obtained from entrance exams and annual checks of workers at two locations: at sea level and at Peruvian highlands (4,100 m), taken by trained staff and equipment calibrated to environmental conditions. We analyzed variations in the course of the years with the PA-GEE statistical test; p values were obtained. Of the 376 workers, 89% (322) were men, the median age was 32 years (range 20-57) and 84% (304) were at high altitude. In multivariate analysis, male sex (p < 0.001), body mass index (BMI; p = 0.021) and working at high altitude (p < 0.001) were associated with the greatest variation of Hb in time, adjusted for age, length, and type of work. These findings should be considered for health surveillance of workers exposed to similar conditions to prevent chronic mountain sickness. The change in Hb of miners was associated with male sex, BMI, and work at high altitude.

[ASSESSMENT OF EXTREME FACTORS OF SHIFT WORK IN ARCTIC CONDITIONS BY WORKERS WITH DIFFERENT REGULATORY PROCESSES].

PubMed

Korneeva, Ya A; Simonova, N N

2016-01-01

A man working on a shift basis in the Arctic, every day is under the influence of various extreme factors which are inevitable for oil and gas indudtry. To adapt to shift work employees use various resources of the individual. The purpose of research is the determination of personal resources of shift workers to overcome the adverse factors of the environment in the Arctic. The study involved 191 builder of main gas pipelines, working in shifts in the Tyumen region (the length of the shift 52 days of arrival) at the age of 23 to 59 (mean age 34.9 ± 8.1) years. Methods: psychological testing, questioning, observation, descriptive statistics, discriminant step by step analysis. There was revealed the correlation between the subjective assessment of the majority of adverse climatic factors in the regulatory process "assessment of results"; production factors--regulatory processes such as flexibility, autonomy, simulation, and the general level of self-regulation; social factors are more associated with the severity of such regulatory processes, flexibility and evaluation of results.

[Length of stay in maternity wards after normal delivery: diverging point of views].

PubMed

Vautrin, E; Fontaine, A; Lanba, P; Guérin, V; Engelmann, P

2000-02-01

To compare maternity ward professionals' and patients' views regarding the length of stay in the maternity after a normal delivery and to explore working relationships with ambulatory health professionals. Three surveys General professional agreement on a minimum of 4 days; few contacts with ambulatory health professionals. One third of the women found their length of stay excessive. Most did not appear to gain new skills after 3 days, nor to encounter major difficulties once they returned to their home. and conclusion. It will be essential to organize effective working relationships between the maternity ward and ambulatory health professionals to ensure appropriate follow-up after an earlier discharge from the hospital, in agreement with the capabilities and expectations of a majority of women.

Alternative Work Patterns as Innovations in the Work Place. Overview: ERIC Fact Sheet No. 19.

ERIC Educational Resources Information Center

Denniston, Denie

Alternative work patterns are work schedules that allow employees to select the hours and length of their workweeks. Reasons for choosing alternative work patterns include transportation considerations, participation in outside activities, ability to work better during certain hours, child care, and household commitments. Examples of alternative…

Determining H2O Vapor Temperature and Concentration in Particle-Free and Particle-Laden Combustion Flows Using Spectral Line Emission Measurements

NASA Astrophysics Data System (ADS)

Tobiasson, John Robert

2017-07-01

There is a growing need for the clean generation of electricity in the world, and increased efficiency is one way to achieve cleaner generation. Increased efficiency may be achieved through an improved understanding of the heat flux of participating media in combustion environments. Real-time in-situ optical measurements of gas temperature and concentrations in combustion environments is needed. Optical methods do not disturb the flow characteristics and are not subject to the temperature limitation of current methods. Simpler, less-costly optical measurements than current methods would increase the ability to apply them in more circumstances. This work explores the ability to simultaneously measure gas temperature and H2O concentration via integrated spectral intensity ratios in regions where H2O is the dominant participating gas. This work considered combustion flows with and without fuel and soot particles, and is an extension of work previously performed by Ellis et al. [1]. Five different combustion regimes were used to investigate the robustness of the infrared intensity integral method first presented by Ellis et al. [1]. These included Post-Flame Natural Gas (PFNG), Post-Flame Medium Wood (PFMW), Post-Flame Fine Wood (PFFW), In-Flame Natural Gas (IFNG), and In-Flame Fine Wood (IFFW). Optical spectra were collected as a function of path length for each regime. Methods for processing the spectra to obtain gas temperature, gas concentration, broadband temperature, and broadband emissivity were developed. A one-dimensional spectral intensity model that allowed for specular reflection, and investigated differences between measured and modeled spectral intensities was created. It was concluded that excellent agreement (within 2.5%) was achieved between optical and suction pyrometer gas temperatures as long as 1) the optical probe and cold target used were well-aligned 2) the path length was greater than 0.3 m and 3) the intensity from broadband emitters within the path was smaller than the gas intensity. Shorter path lengths between 0.15 - 0.3 m produced reasonable temperatures with 7% error while path lengths of 0.05 m or less were as much as 15% in error or the signal would not effectively process. Water vapor concentration was less accurate being at best within 20% (relative) of expected values. The accurate determination of concentration requires first an accurate temperature concentration as well low broadband participation. Some optical concentrations were in error as much as 85%. The 1-D model was compared to the measurement and it was found that the model peaks were sharper and shifted 0.167 cm-1 compared to the measured data. The reason for the shift can be attributed to the uncertainty of the reference laser frequency used in the FTIR. No conclusion was found for the cause of the sharper peaks in the model. The integrated area of bands used to find temperature and concentration matched well between the model and measured spectrum being typically within 3%.

Effect of the specimen length on ultrasonic P-wave velocity in some volcanic rocks and limestones

NASA Astrophysics Data System (ADS)

Karaman, Kadir; Kaya, Ayberk; Kesimal, Ayhan

2015-12-01

Ultrasonic P-wave velocity (UPV) is commonly used in different fields such as civil, mining, geotechnical, and rock engineering. One of the significant parameters which affect the UPV of rock materials is likely to be the length of test cores although it is not mentioned in the literature. In this study, in order to explore the influence of the specimen length on the UPV, rock samples were collected from eight different locations in Turkey. The NX-sized core specimens having different length of 50, 75, 100, 125, and 150 mm were prepared. Before the analyses, rocks were divided into two groups in terms of their geological origins such as volcanic and chemical sedimentary (limestone) rocks. The UPV tests were carried out under dry and saturated conditions for each 200 core specimens. By evaluating the test results, it was shown that the length of the specimens significantly affects the UPV values. Based on the regression analyses, a method was developed to determine the threshold specimen length of studied rocks. Fluctuations in UPVdry and UPVsat values were generally observed for cores smaller than the threshold specimen length. In this study, the threshold specimen length was determined as 79 mm for volcanic rocks and 109 mm for limestones.

Active microrheology of entangled biopolymer composites link polymer flexibility and length to molecular force response

NASA Astrophysics Data System (ADS)

Fitzpatrick, Robert; Hauer, Cole; Kyrillos, Carl; McGorty, Ryan; Robertson-Anderson, Rae

Entangled polymers have complex viscoelastic properties that are tuned by polymer lengths and flexibilities. Entangled composites of distinct polymers offer added versatility and display nonlinear mechanics, serving as a platform for multifunctional materials. To determine the role of flexibility and length in polymer composites we use optical tweezers and confocal microscopy to measure mechanical and structural properties of co-entangled actin and DNA. Actin filaments have lengths of 5-20 μm, comparable to their persistence length, while DNA of similar lengths have hundreds of persistence lengths per chain. To characterize the nonlinear mechanics of actin-DNA composites, we optically drive a microsphere through the composite and measure the induced force during and following strain. We characterize viscoelasticity and relaxation timescales; and determine the dependence of these quantities on the actin:DNA ratio (0:1-1:0) and DNA length (4-100 μm). We use confocal microscopy to image distinctly labeled co-entangled actin and DNA and characterize network homogeneity and fluctuations. Initial results show actin and DNA are well-integrated and form structurally homogenous networks that exhibit stiffness and relaxation times that increase nonlinearly with increased actin. NSF Career Award (DMR-1254340), AFOSR Young Investigator Program Award (FA95550-12-1-0315), Scialog Collaborative Innovation Award funed by Research Corp. for Scientific Advancement (24192).

Dark-field microscopy studies of single metal nanoparticles: understanding the factors that influence the linewidth of the localized surface plasmon resonance

PubMed Central

Hu, Min; Novo, Carolina; Funston, Alison; Wang, Haining; Staleva, Hristina; Zou, Shengli; Mulvaney, Paul; Xia, Younan; Hartland, Gregory V.

2008-01-01

This article provides a review of our recent Rayleigh scattering measurements on single metal nanoparticles. Two different systems will be discussed in detail: gold nanorods with lengths between 30 and 80 nm, and widths between 8 and 30 nm; and hollow gold–silver nanocubes (termed nanoboxes or nanocages depending on their exact morphology) with edge lengths between 100 and 160 nm, and wall thicknesses of the order of 10 nm. The goal of this work is to understand how the linewidth of the localized surface plasmon resonance depends on the size, shape, and environment of the nanoparticles. Specifically, the relative contributions from bulk dephasing, electron–surface scattering, and radiation damping (energy loss via coupling to the radiation field) have been determined by examining particles with different dimensions. This separation is possible because the magnitude of the radiation damping effect is proportional to the particle volume, whereas, the electron–surface scattering contribution is inversely proportional to the dimensions. For the nanorods, radiation damping is the dominant effect for thick rods (widths greater than 20 nm), while electron–surface scattering is dominant for thin rods (widths less than 10 nm). Rods with widths in between these limits have narrow resonances—approaching the value determined by the bulk contribution. For nanoboxes and nanocages, both radiation damping and electron–surface scattering are significant at all sizes. This is because these materials have thin walls, but large edge lengths and, therefore, relatively large volumes. The effect of the environment on the localized surface plasmon resonance has also been studied for nanoboxes. Increasing the dielectric constant of the surroundings causes a red-shift and an increase in the linewidth of the plasmon band. The increase in linewidth is attributed to enhanced radiation damping. PMID:18846243

Dark-field microscopy studies of single metal nanoparticles: understanding the factors that influence the linewidth of the localized surface plasmon resonance.

PubMed

Hu, Min; Novo, Carolina; Funston, Alison; Wang, Haining; Staleva, Hristina; Zou, Shengli; Mulvaney, Paul; Xia, Younan; Hartland, Gregory V

2008-01-01

This article provides a review of our recent Rayleigh scattering measurements on single metal nanoparticles. Two different systems will be discussed in detail: gold nanorods with lengths between 30 and 80 nm, and widths between 8 and 30 nm; and hollow gold-silver nanocubes (termed nanoboxes or nanocages depending on their exact morphology) with edge lengths between 100 and 160 nm, and wall thicknesses of the order of 10 nm. The goal of this work is to understand how the linewidth of the localized surface plasmon resonance depends on the size, shape, and environment of the nanoparticles. Specifically, the relative contributions from bulk dephasing, electron-surface scattering, and radiation damping (energy loss via coupling to the radiation field) have been determined by examining particles with different dimensions. This separation is possible because the magnitude of the radiation damping effect is proportional to the particle volume, whereas, the electron-surface scattering contribution is inversely proportional to the dimensions. For the nanorods, radiation damping is the dominant effect for thick rods (widths greater than 20 nm), while electron-surface scattering is dominant for thin rods (widths less than 10 nm). Rods with widths in between these limits have narrow resonances-approaching the value determined by the bulk contribution. For nanoboxes and nanocages, both radiation damping and electron-surface scattering are significant at all sizes. This is because these materials have thin walls, but large edge lengths and, therefore, relatively large volumes. The effect of the environment on the localized surface plasmon resonance has also been studied for nanoboxes. Increasing the dielectric constant of the surroundings causes a red-shift and an increase in the linewidth of the plasmon band. The increase in linewidth is attributed to enhanced radiation damping.

Sizing Up the Milky Way: A Bayesian Mixture Model Meta-analysis of Photometric Scale Length Measurements

NASA Astrophysics Data System (ADS)

Licquia, Timothy C.; Newman, Jeffrey A.

2016-11-01

The exponential scale length (L d ) of the Milky Way’s (MW’s) disk is a critical parameter for describing the global physical size of our Galaxy, important both for interpreting other Galactic measurements and helping us to understand how our Galaxy fits into extragalactic contexts. Unfortunately, current estimates span a wide range of values and are often statistically incompatible with one another. Here, we perform a Bayesian meta-analysis to determine an improved, aggregate estimate for L d , utilizing a mixture-model approach to account for the possibility that any one measurement has not properly accounted for all statistical or systematic errors. Within this machinery, we explore a variety of ways of modeling the nature of problematic measurements, and then employ a Bayesian model averaging technique to derive net posterior distributions that incorporate any model-selection uncertainty. Our meta-analysis combines 29 different (15 visible and 14 infrared) photometric measurements of L d available in the literature; these involve a broad assortment of observational data sets, MW models and assumptions, and methodologies, all tabulated herein. Analyzing the visible and infrared measurements separately yields estimates for L d of {2.71}-0.20+0.22 kpc and {2.51}-0.13+0.15 kpc, respectively, whereas considering them all combined yields 2.64 ± 0.13 kpc. The ratio between the visible and infrared scale lengths determined here is very similar to that measured in external spiral galaxies. We use these results to update the model of the Galactic disk from our previous work, constraining its stellar mass to be {4.8}-1.1+1.5× {10}10 M ⊙, and the MW’s total stellar mass to be {5.7}-1.1+1.5× {10}10 M ⊙.

Scale Dependence of Statistics of Spatially Averaged Rain Rate Seen in TOGA COARE Comparison with Predictions from a Stochastic Model

NASA Technical Reports Server (NTRS)

Kundu, Prasun K.; Bell, T. L.; Lau, William K. M. (Technical Monitor)

2002-01-01

A characteristic feature of rainfall statistics is that they in general depend on the space and time scales over which rain data are averaged. As a part of an earlier effort to determine the sampling error of satellite rain averages, a space-time model of rainfall statistics was developed to describe the statistics of gridded rain observed in GATE. The model allows one to compute the second moment statistics of space- and time-averaged rain rate which can be fitted to satellite or rain gauge data to determine the four model parameters appearing in the precipitation spectrum - an overall strength parameter, a characteristic length separating the long and short wavelength regimes and a characteristic relaxation time for decay of the autocorrelation of the instantaneous local rain rate and a certain 'fractal' power law exponent. For area-averaged instantaneous rain rate, this exponent governs the power law dependence of these statistics on the averaging length scale $L$ predicted by the model in the limit of small $L$. In particular, the variance of rain rate averaged over an $L \\times L$ area exhibits a power law singularity as $L \\rightarrow 0$. In the present work the model is used to investigate how the statistics of area-averaged rain rate over the tropical Western Pacific measured with ship borne radar during TOGA COARE (Tropical Ocean Global Atmosphere Coupled Ocean Atmospheric Response Experiment) and gridded on a 2 km grid depends on the size of the spatial averaging scale. Good agreement is found between the data and predictions from the model over a wide range of averaging length scales.

Efficacy of irrigation systems on penetration of sodium hypochlorite to working length and to simulated uninstrumented areas in oval shaped root canals.

PubMed

de Gregorio, C; Paranjpe, A; Garcia, A; Navarrete, N; Estevez, R; Esplugues, E O; Cohenca, N

2012-05-01

To assess the ability of sodium hypochlorite (NaOCl) to penetrate simulated lateral canals and to reach working length (WL) when using the self-adjusting file (SAF). Seventy single-rooted teeth with oval-shaped canals were used. Upon access, presence of a single canal was confirmed by direct visualization under a dental-operating microscope. Canal length and patency were obtained using a size 10 K-file and root length standardized to 18 mm. Pre-enlargement was restricted to the coronal one-third. The apical size of each canal was gauged at WL and samples larger than size 30 were excluded. Canals were instrumented for 5 min using the SAF system while delivering a total of 20 mL of 5.25% NaOCl and 5 mL of 17% EDTA. Then, the apical diameters were standardized to size 35 using hand files. Four hundred and twenty simulated lateral canals were then created during the clearing process and roots coated with wax to create a closed system. All samples were then cleared and randomly assigned to four experimental groups: 1 (n = 15) positive pressure; 2 (n = 15) SAF without pecking motion; 3 (n = 15) SAF with pecking motion; 4 (n = 15) apical negative pressure (ANP) irrigation and (n = 10) control groups. Samples were scored on the basis of the ability of the contrast solution to reach WL and permeate into the simulated lateral canals to at least 50% of the total length. The Kruskal-Wallis test was used to analyse irrigant penetration and the Tukey test to determine statistical differences between groups (P < 0.05). All samples irrigated with ANP were associated with irrigant penetration to WL (Table 1). The differences between group 4 (ANP) and all other groups were significant in penetration to WL (P < 0.05). The pecking motion allowed for further penetration of the irrigant when using the SAF system but failed to irrigate at WL. None of the experimental groups demonstrated predictable irrigation of simulated lateral canals. In this laboratory model, ANP was the only delivery system capable of irrigating consistently to full WL. None of the systems tested produced complete irrigation in artificial lateral canals. © 2012 International Endodontic Journal.

Is increased residual shank length a competitive advantage for elite transtibial amputee long jumpers?

PubMed

Nolan, Lee; Patritti, Benjamin L; Stana, Laura; Tweedy, Sean M

2011-07-01

The purpose of this study was to evaluate the extent to which residual shank length affects long jump performance of elite athletes with a unilateral transtibial amputation. Sixteen elite, male, long jumpers with a transtibial amputation were videoed while competing in major championships (World Championships 1998, 2002 and Paralympic Games, 2004). The approach, take-off, and landing of each athlete's best jump was digitized to determine residual and intact shank lengths, jump distance, and horizontal and vertical velocity of center of mass at touchdown. Residual shank length ranged from 15 cm to 38 cm. There were weak, nonsignificant relationships between residual shank length and (a) distance jumped (r = 0.30), (b) horizontal velocity (r = 0.31), and vertical velocity (r = 0.05). Based on these results, residual shank length is not an important determinant of long jump performance, and it is therefore appropriate that all long jumpers with transtibial amputation compete in the same class. The relationship between residual shank length and key performance variables was stronger among athletes that jumped off their prosthetic leg (N = 5), and although this result must be interpreted cautiously, it indicates the need for further research.

Invariance of single-file water mobility in gramicidin-like peptidic pores as function of pore length.

PubMed

Portella, Guillem; Pohl, Peter; de Groot, Bert L

2007-06-01

We investigated the structural and energetic determinants underlying water permeation through peptidic nanopores, motivated by recent experimental findings that indicate that water mobility in single-file water channels displays nonlinear length dependence. To address the molecular mechanism determining the observed length dependence, we studied water permeability in a series of designed gramicidin-like channels of different length using atomistic molecular dynamics simulations. We found that within the studied range of length the osmotic water permeability is independent of pore length. This result is at variance with textbook models, where the relationship is assumed to be linear. Energetic analysis shows that loss of solvation rather than specific water binding sites in the pore form the main energetic barrier for water permeation, consistent with our dynamics results. For this situation, we propose a modified expression for osmotic permeability that fully takes into account water motion collectivity and does not depend on the pore length. Different schematic barrier profiles are discussed that explain both experimental and computational interpretations, and we propose a set of experiments aimed at validation of the presented results. Implications of the results for the design of peptidic channels with desired permeation characteristics are discussed.

Determination of three-dimensional muscle architectures: validation of the DTI-based fiber tractography method by manual digitization

PubMed Central

Schenk, P; Siebert, T; Hiepe, P; Güllmar, D; Reichenbach, J R; Wick, C; Blickhan, R; Böl, M

2013-01-01

In the last decade, diffusion tensor imaging (DTI) has been used increasingly to investigate three-dimensional (3D) muscle architectures. So far there is no study that has proved the validity of this method to determine fascicle lengths and pennation angles within a whole muscle. To verify the DTI method, fascicle lengths of m. soleus as well as their pennation angles have been measured using two different methods. First, the 3D muscle architecture was analyzed in vivo applying the DTI method with subsequent deterministic fiber tractography. In a second step, the muscle architecture of the same muscle was analyzed using a standard manual digitization system (MicroScribe MLX). Comparing both methods, we found differences for the median pennation angles (P < 0.001) but not for the median fascicle lengths (P = 0.216). Despite the statistical results, we conclude that the DTI method is appropriate to determine the global fiber orientation. The difference in median pennation angles determined with both methods is only about 1.2° (median pennation angle of MicroScribe: 9.7°; DTI: 8.5°) and probably has no practical relevance for muscle simulation studies. Determining fascicle lengths requires additional restriction and further development of the DTI method. PMID:23678961

Determination of three-dimensional muscle architectures: validation of the DTI-based fiber tractography method by manual digitization.

PubMed

Schenk, P; Siebert, T; Hiepe, P; Güllmar, D; Reichenbach, J R; Wick, C; Blickhan, R; Böl, M

2013-07-01

In the last decade, diffusion tensor imaging (DTI) has been used increasingly to investigate three-dimensional (3D) muscle architectures. So far there is no study that has proved the validity of this method to determine fascicle lengths and pennation angles within a whole muscle. To verify the DTI method, fascicle lengths of m. soleus as well as their pennation angles have been measured using two different methods. First, the 3D muscle architecture was analyzed in vivo applying the DTI method with subsequent deterministic fiber tractography. In a second step, the muscle architecture of the same muscle was analyzed using a standard manual digitization system (MicroScribe MLX). Comparing both methods, we found differences for the median pennation angles (P < 0.001) but not for the median fascicle lengths (P = 0.216). Despite the statistical results, we conclude that the DTI method is appropriate to determine the global fiber orientation. The difference in median pennation angles determined with both methods is only about 1.2° (median pennation angle of MicroScribe: 9.7°; DTI: 8.5°) and probably has no practical relevance for muscle simulation studies. Determining fascicle lengths requires additional restriction and further development of the DTI method. © 2013 Anatomical Society.

Predictive value of magnetic resonance imaging determined tumor contact length for extracapsular extension of prostate cancer.

PubMed

Baco, Eduard; Rud, Erik; Vlatkovic, Ljiljana; Svindland, Aud; Eggesbø, Heidi B; Hung, Andrew J; Matsugasumi, Toru; Bernhard, Jean-Christophe; Gill, Inderbir S; Ukimura, Osamu

2015-02-01

Tumor contact length is defined as the amount of prostate cancer in contact with the prostatic capsule. We evaluated the ability of magnetic resonance imaging determined tumor contact length to predict microscopic extracapsular extension compared to existing predictors of extracapsular extension. We retrospectively analyzed the records of 111 consecutive patients with magnetic resonance imaging/ultrasound fusion targeted, biopsy proven prostate cancer who underwent radical prostatectomy from January 2010 to July 2013. Median patient age was 64 years and median prostate specific antigen was 8.9 ng/ml. Clinical stage was cT1 in 93 cases (84%) and cT2 in 18 (16%). Postoperative pathological analysis confirmed pT2 in 71 patients (64%) and pT3 in 40 (36%). We evaluated 1) in the radical prostatectomy specimen the correlation of microscopic extracapsular extension with pathological cancer volume, pathological tumor contact length and Gleason score, 2) the correlation between microscopic extracapsular extension and magnetic resonance imaging tumor contact length, and 3) the ability of preoperative variables to predict microscopic extracapsular extension. Logistic regression analysis revealed that pathological tumor contact length correlated better with microscopic extracapsular extension than the predictive power of pathological cancer volume (0.821 vs 0.685). The Spearman correlation between pathological and magnetic resonance imaging tumor contact length was r = 0.839 (p <0.0001). ROC AUC analysis revealed that magnetic resonance imaging tumor contact length outperformed cancer core involvement on targeted biopsy and the Partin tables to predict microscopic extracapsular extension (0.88 vs 0.70 and 0.63, respectively). At a magnetic resonance imaging tumor contact length threshold of 20 mm the accuracy for diagnosing microscopic extracapsular extension was superior to that of conventional magnetic resonance imaging criteria (82% vs 67%, p = 0.015). We developed a predicted probability plot curve of extracapsular extension according to magnetic resonance imaging tumor contact length. Magnetic resonance imaging determined tumor contact length could be a promising quantitative predictor of microscopic extracapsular extension. Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Stretch-induced, steady-state force enhancement in single skeletal muscle fibers exceeds the isometric force at optimum fiber length.

PubMed

Rassier, Dilson E; Herzog, Walter; Wakeling, Jennifer; Syme, Douglas A

2003-09-01

Stretch-induced force enhancement has been observed in a variety of muscle preparations and on structural levels ranging from single fibers to in vivo human muscles. It is a well-accepted property of skeletal muscle. However, the mechanism causing force enhancement has not been elucidated, although the sarcomere-length non-uniformity theory has received wide support. The purpose of this paper was to re-investigate stretch-induced force enhancement in frog single fibers by testing specific hypotheses arising from the sarcomere-length non-uniformity theory. Single fibers dissected from frog tibialis anterior (TA) and lumbricals (n=12 and 22, respectively) were mounted in an experimental chamber with physiological Ringer's solution (pH=7.5) between a force transducer and a servomotor length controller. The tetantic force-length relationship was determined. Isometric reference forces were determined at optimum length (corresponding to the maximal, active, isometric force), and at the initial and final lengths of the stretch experiments. Stretch experiments were performed on the descending limb of the force-length relationship after maximal tetanic force was reached. Stretches of 2.5-10% (TA) and 5-15% lumbricals of fiber length were performed at 0.1-1.5 fiber lengths/s. The stretch-induced, steady-state, active isometric force was always equal or greater than the purely isometric force at the muscle length from which the stretch was initiated. Moreover, for stretches of 5% fiber length or greater, and initiated near the optimum length of the fiber, the stretch-enhanced active force always exceeded the maximal active isometric force at optimum length. Finally, we observed a stretch-induced enhancement of passive force. We conclude from these results that the sarcomere length non-uniformity theory alone cannot explain the observed force enhancement, and that part of the force enhancement is associated with a passive force that is substantially greater after active compared to passive muscle stretch.

Difference of the associations between self-rated health and demographic characteristics, lifestyle, and psychosocial work environment between two types of Chinese worksite.

PubMed

Jia, Yingnan; Gao, Junling; Dai, Junming; Zheng, Pinpin; Wu, Xiaoyu; Li, Guangyao; Fu, Hua

2014-08-15

Although studies of self-rated health (SRH) are conducted widely in developed countries, comprehensive assessments of the determinants of SRH in Chinese are scarce, particularly for working Chinese individuals. Determinants of SRH might differ among worksites based on differences in the nature and stress associated with different jobs, work intensity, and the lifestyles of employees. Two thousand and forty questionnaires that addressed SRH, demographic characteristics, lifestyle, and the psychosocial work environment were administered to employees at two worksites. A total of 1644 subjects provided complete data for analysis (80.6% response rate). Participants from government departments had significantly better SRH than did those from high-tech enterprises (61.1% vs. 67.5%, respectively). Lifestyles were significantly less healthy at government departments compared with high-tech enterprises, whereas the psychosocial work environment was better. The results of unadjusted and adjusted models revealed differences between the potential health-influencing factors of participants based on their type of worksite. In logistic regression models, gender was strongly associated with SRH in all participants, whereas length of service was correlated with SRH only in participants from high-tech enterprises. In high-tech enterprises, good SRH was less common in physically inactive subjects vs. physically active participants (OR = 0.561). In government departments, passive smoking was negatively associated with SRH significantly. Social capital (OR = 1.073) and job control (OR = 1.550) were positively correlated with SRH in high-tech enterprises. Job control was the only psychosocial factor significantly associated with SRH in government departments. Participants from different types of worksite reported different SRH, healthy lifestyles, and psychosocial work environments. Moreover, the association between SRH and demographic characteristics, lifestyle, and the psychosocial work environment significantly differed by type of worksite.

Estimating live fuel status by drought indices: an approach for assessing local impact of climate change on fire danger

NASA Astrophysics Data System (ADS)

Pellizzaro, Grazia; Dubrovsky, Martin; Bortolu, Sara; Ventura, Andrea; Arca, Bachisio; Masia, Pierpaolo; Duce, Pierpaolo

2014-05-01

Mediterranean shrubs are an important component of both Mediterranean vegetation communities and understorey vegetation. They also constitute the surface fuels primarily responsible for the ignition and the spread of wildland fires in Mediterranean forests. Although fire spread and behaviour are dependent on several factors, the water content of live fuel plays an important role in determining fire occurrence and spread, especially in the Mediterranean shrubland, where live fuel is often the main component of the available fuel which catches fire. According to projections on future climate, an increase in risk of summer droughts is likely to take place in Southern Europe. More prolonged drought seasons induced by climatic changes are likely to influence general flammability characteristics of fuel, affecting load distribution in vegetation strata, floristic composition, and live and dead fuel ratio. In addition, variations in precipitation and mean temperature could directly affect fuel water status, and consequently flammability, and length of critical periods of high ignition danger for Mediterranean ecosystems. The main aim of this work was to propose a methodology for evaluating possible impacts of future climate change on moisture dynamic and length of fire danger period at local scale. Specific objectives were: i) evaluating performances of meteorological drought indices in describing seasonal pattern of live fuel moisture content (LFMC), and ii) simulating the potential impacts of future climate changes on the duration of fire danger period. Measurements of LFMC seasonal pattern of three Mediterranean shrub species were performed in North Western Sardinia (Italy) for 8 years. Seasonal patterns of LFMC were compared with the Drought Code of the Canadian Forest Fire Weather Index and the Keetch-Byram Drought Index. Analysis of frequency distribution and cumulative distribution curves were carried out in order to evaluate performance of codes and to identify threshold values of indices useful to determine the end of the potential fire season due to fuel status. A weather generator linked to climate change scenarios derived from 17 available General Circulation Models (GCMs) was used to produce synthetic weather series, representing present and future climates, for four selected sites located in North Sardinia, Italy. Finally, impacts of future climate change on fire season length at local scale were simulated. Results confirmed that the projected climate scenarios over the Mediterranean area will determine an overall increase of the fire season length.

APPLICATION OF RADIOISOTOPES TO THE QUANTITATIVE CHROMATOGRAPHY OF FATTY ACIDS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Budzynski, A.Z.; Zubrzycki, Z.J.; Campbell, I.G.

1959-10-31

The paper reports work done on the use of I/sup 131/, Zn/sup 65/, Sr/sup 90/, Zr/sup 95/, Ce/sup 144/ for the quantitative estimation of fatty acids on paper chromatograms, and for determination of the degree of usaturation of components of resolved fatty acid mixtures. I/sup 131/ is used to iodinate unsaturated fatty acids, and the amount of such acids is determined from the radiochromatogram. The degree of unsaturation of fatty acids is determined by estimation of the specific activiiy of spots. The other isotopes have been examined from the point of view of their suitability for estimation of total amountsmore » of fatty acids by formation of insoluble radioactive soaps held on the chromatogram. In particular, work is reported on the quantitative estimation of saturated fatty acids by measurement of the activity of their insoluble soaps with radioactive metals. Various quantitative relationships are described between amount of fatty acid in spot and such parameters as radiometrically estimated spot length, width, maximum intensity, and integrated spot activity. A convenient detection apparatus for taking radiochromatograms is also described. In conjunction with conventional chromatographic methods for resolving fatty acids the method permits the estimation of composition of fatty acid mixtures obtained from biological material. (auth)« less

Determinants of clergy behaviors promoting safety of battered Korean immigrant women.

PubMed

Choi, Y Joon

2015-03-01

Korean immigrants rely heavily on their respective churches for assistance with domestic violence. Yet, Korean clergy's responses to domestic violence are unknown. The purpose of this study was to examine factors that influence Korean clergy's responses to domestic violence in their congregations. Results showed that clergy's Korean cultural values, age, and length of residence in the United States influence their responses to domestic violence. Developing a collaborative working relationship between Korean clergy and domestic violence advocates, as well as providing training to Korean clergy targeting their knowledge, beliefs/attitudes, and skills is critical for promoting safety of battered Korean immigrant women. © The Author(s) 2015.

LOD First Estimates In 7406 SLR San Juan Argentina Station

NASA Astrophysics Data System (ADS)

Pacheco, A.; Podestá, R.; Yin, Z.; Adarvez, S.; Liu, W.; Zhao, L.; Alvis Rojas, H.; Actis, E.; Quinteros, J.; Alacoria, J.

2015-10-01

In this paper we show results derived from satellite observations at the San Juan SLR station of Felix Aguilar Astronomical Observatory (OAFA). The Satellite Laser Ranging (SLR) telescope was installed in early 2006, in accordance with an international cooperation agreement between the San Juan National University (UNSJ) and the Chinese Academy of Sciences (CAS). The SLR has been in successful operation since 2011 using NAOC SLR software for the data processing. This program was designed to calculate satellite orbits and station coordinates, however it was used in this work for the determination of LOD (Length Of Day) time series and Earth Rotation speed.

A general equilibrium model of guest-worker migration: the source-country perspective.

PubMed

Djajic, S; Milbourne, R

1988-11-01

"This paper examines the problem of guest-worker migration from an economy populated by identical, utility-maximizing individuals with finite working lives. The decision to migrate, the rate of saving while abroad, as well as the length of a migrant's stay in the foreign country, are all viewed as part of a solution to an intertemporal optimization problem. In addition to studying the microeconomic aspects of temporary migration, the paper analyses the determinants of the equilibrium flow of migrants, the corresponding domestic wage, and the level of welfare enjoyed by a typical worker. Effects of an emigration tax are also investigated." excerpt

Multi-Scale Structure of Coacervates formed by Oppositely Charged Polyelectrolytes

NASA Astrophysics Data System (ADS)

Rubinstein, Michael

We develop a scaling model of coacervates formed by oppositely charged polyelectrolytes and demonstrate that they self-organize into multi-scale structures. The intramolecular electrostatic interactions in dilute polyanion or polycation solutions are characterized by the electrostatic blobs with size D- and D+ respectively, that repel neighboring blobs on the same chains with electrostatic energy on the order of thermal energy kT . After mixing, electrostatic intramolecular repulsion of polyelectrolytes with higher charged density, say polyanions, keeps these polyanions in coacervates aligned into stretched arrays of electrostatic blobs of size D-

Chemical Reactions in Turbulent Mixing Flows.

DTIC Science & Technology

1986-04-10

fluctuation of the " flame " length of such reactingjeatreent wer copoit sequencd shout tnhawate facility, documented previously’,’ 1 , using laser jets. A...motion film of such a chemically reacting turbulent jet visualized using this technique, is shown in figure 1. In each I. Flame length fluctuations of...acid-base reaction to determine length and time to allow a simultaneous view of mixing in the two scales for the flame length fluctuations of thin

Measuring short electron bunch lengths using coherent smith-purcell radiation

DOEpatents

Nguyen, Dinh C.

1999-01-01

A method is provided for directly determining the length of sub-picosecond electron bunches. A metallic grating is formed with a groove spacing greater than a length expected for the electron bunches. The electron bunches are passed over the metallic grating to generate coherent and incoherent Smith-Purcell radiation. The angular distribution of the coherent Smith-Purcell radiation is then mapped to directly deduce the length of the electron bunches.

Measuring short electron bunch lengths using coherent Smith-Purcell radiation

DOEpatents

Nguyen, D.C.

1999-03-30

A method is provided for directly determining the length of sub-picosecond electron bunches. A metallic grating is formed with a groove spacing greater than a length expected for the electron bunches. The electron bunches are passed over the metallic grating to generate coherent and incoherent Smith-Purcell radiation. The angular distribution of the coherent Smith-Purcell radiation is then mapped to directly deduce the length of the electron bunches. 8 figs.

76 FR 50996 - Affirmative Final Determination of Circumvention of the Antidumping Duty Order on Certain Cut-to...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... Determination of Circumvention of the Antidumping Duty Order on Certain Cut-to-Length Carbon Steel Plate From... products were circumventing the antidumping duty order on certain cut-to-length carbon steel plate from the... produced by Wuyang Iron and Steel Co., Ltd. (Wuyang), but also noted the Department intended ``to address...

77 FR 64223 - Federal Benefit Payments Under Certain District of Columbia Retirement Plans

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-19

...) The benefit is based on the death of an employee after June 30, 1997 and the survivor benefit is not..., applies to death benefits that are determined by length of service. In these cases, the survivor's Federal... and separated on June 30, 1997, does not apply to death benefits that are not determined by length of...

75 FR 71047 - Federal Benefit Payments Under Certain District of Columbia Retirement Plans

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-22

... Federal Benefit Payment for survivors when death benefits are not determined by the length of service... when death benefits are determined by the length of service. Section 29.344(c) is added to provide the... retirement is based on disability after June 30, 1997 (see 29.343); or (3) The benefit is based on the death...

Calibration of highway safety manual work zone crash modification factors.

DOT National Transportation Integrated Search

2014-06-01

The Highway Safety Manual is the national safety manual that provides quantitative methods for analyzing highway safety. The : HSM presents crash modification factors related to work zone characteristics such as work zone duration and length. These c...

Sex determination from hand and foot dimensions in a North Indian population.

PubMed

Krishan, Kewal; Kanchan, Tanuj; Sharma, Abhilasha

2011-03-01

Hands and feet are often recovered from the site of natural as well as man-made disasters because of bomb blasts, train accidents, plane crashes, or mass homicides. This study is intended to establish standards for determination of sex from the dimensions of hands and feet in a North Indian population. The data for this study comprise 123 men and 123 women aged between 17 and 20 years from the "Rajput" population of Himachal Pradesh in North India. Four anthropometric measurements viz. hand length, hand breadth, foot length, and foot breadth have been taken on both sides of each subject following international anthropometric standards. The hand index (hand breadth/hand length × 100) and the foot index (foot breadth/foot length × 100) were calculated. Sectioning points and regression models are derived for the hand and foot dimensions and the derived indices. The hand and foot dimensions show a higher accuracy in sex determination by sectioning point analysis when compared to hand and foot index. Of the hand and the foot dimensions, hand breadth and foot breadth showed better accuracy in sex determination. Hand index and foot index remain poor sex discriminators in the study. © 2011 American Academy of Forensic Sciences.

Generation of irradiance patterns using a semi-spherical meter of two degrees of freedom

NASA Astrophysics Data System (ADS)

Tecpoyotl-Torres, M.; Vera-Dimas, J. G.; Escobedo-Alatorre, J.; Sánchez-Mondragón, J.; Torres-Cisneros, M.; Cabello-Ruiz, R.; Varona, J.

2011-09-01

The meter device presented in this work consists of a photo-detector mounted on the mechanism of a mobile rectangular arc. One stepper motor located on the lateral axis of the device displaces the sensor along a semi-circular trajectory of 170°, almost half meridians. Another motor located at the base of the device enables 360° rotation of the illumination source under test. This arrangement effectively produces a semi-spherical volume for the sensor to move within. The number of measurement points is determined by programming the two stepper motors. Also, the use of a single photo-sensor ensures uniformity in the measurements. The mechanical structure provides enough rigidity for supporting the accuracy required by the data acquisition circuitry based on a DSPIC. Measurement of illumination sources of different sizes is possible by using adjustable lengths of the mobile base and the ring for a maximum lamp length of 0.16 m. Because this work is partially supported by a private entity interested in the characterization of its products, especial attention has been given to the luminaries based on LED technology with divergent beams. The received power by the detector is useful to obtain the irradiance profile of the lighting source under test. The meter device presented herein is a low-cost prototype designed and fabricated using recyclable materials only such as "electronic waste".

[Effect of the sociodemographic, occupational, organisational and environmental variables on the duration of temporary sick leave in Spain].

PubMed

Villaplana García, María; Sáez Navarro, Concepción; Meseguer de Pedro, Mariano; García-Izquierdo, Mariano

2015-02-01

This study examines the relationship, and relevance of the effect between the duration of the cases of temporary sick leave, as an indicator of absenteeism, and several characteristics (sociodemographic, labor, organizational and the environment) of workers covered by the Social Security System in Spain. A retrospective analysis was conducted on 598,988 processes, between 15 and 365days. The relationships between length of absence, and several characteristics such as demographic, sociodemographic, occupational, organizational and environment characteristics were determined (using P values). The mean duration for each of the features is described, and the size effect is calculated to estimate the importance of the relationships found. There were significant relationships between the duration of temporary sick leave and several demographic characteristics (gender, age, nationality and length of service), occupational (wages, type of contract), organizational (economic sector, activity and size company), the environmental (region, state) characteristics. The age also showed a significant size effect (rxy=.134), especially after age 44. Only age had a significance effect on the duration of work absence, although there was also a relationship with the rest of the demographic, occupational and work environment characteristics. There was also evidence of a cross-effects between the variables, which could cause errors in interpreting the results. Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

Moving contact lines on vibrating surfaces

NASA Astrophysics Data System (ADS)

Solomenko, Zlatko; Spelt, Peter; Scott, Julian

2017-11-01

Large-scale simulations of flows with moving contact lines for realistic conditions generally requires a subgrid scale model (analyses based on matched asymptotics) to account for the unresolved part of the flow, given the large range of length scales involved near contact lines. Existing models for the interface shape in the contact-line region are primarily for steady flows on homogeneous substrates, with encouraging results in 3D simulations. Introduction of complexities would require further investigation of the contact-line region, however. Here we study flows with moving contact lines on planar substrates subject to vibrations, with applications in controlling wetting/dewetting. The challenge here is to determine the change in interface shape near contact lines due to vibrations. To develop further insight, 2D direct numerical simulations (wherein the flow is resolved down to an imposed slip length) have been performed to enable comparison with asymptotic theory, which is also developed further. Perspectives will also be presented on the final objective of the work, which is to develop a subgrid scale model that can be utilized in large-scale simulations. The authors gratefully acknowledge the ANR for financial support (ANR-15-CE08-0031) and the meso-centre FLMSN for use of computational resources. This work was Granted access to the HPC resources of CINES under the allocation A0012B06893 made by GENCI.

The potential of human toe flexor muscles to produce force

PubMed Central

Goldmann, Jan-Peter; Brüggemann, Gert-Peter

2012-01-01

The maximal force a muscle produces depends among others on the length of the muscle and therefore on the positions of the joints the muscle crosses. Long and short toe flexor muscles (TFM) cross the ankle joints and metatarsal phalangeal joints (MPJ) and work against gravity during human locomotion. The purpose of this study was to describe the maximal moments around the MPJ during maximal voluntary isometric contractions (MVIC) of the TFM as a function of ankle joint and MPJ position. Twenty men performed MVIC of the TFM in a custom-made dynamometer. Ankle and MPJ angles were modified after each contraction. External moments of force around the MPJ were determined. Moments ranged between 6.3 ± 2.6 Nm and 14.2 ± 5.8 Nm. Highest moments were produced at 0°–10° ankle joint dorsal flexion and 25°–45° MPJ dorsal flexion. Lowest moments were generated at 35° ankle joint plantar flexion and 0° MPJ dorsal flexion. In conclusion, if the ankle is plantar-flexed, dorsal flexion of the MPJ avoids a disadvantage of the force–length relationship of TFM. Therefore, MPJ dorsal flexion is a necessary function in the push-off phase of human locomotion to work against the loss of the mechanical output at the forefoot caused by plantar flexion of the ankle. PMID:22747582

On the Minimal Length Uncertainty Relation and the Foundations of String Theory

DOE PAGES

Chang, Lay Nam; Lewis, Zachary; Minic, Djordje; ...

2011-01-01

We review our work on the minimal length uncertainty relation as suggested by perturbative string theory. We discuss simple phenomenological implications of the minimal length uncertainty relation and then argue that the combination of the principles of quantum theory and general relativity allow for a dynamical energy-momentum space. We discuss the implication of this for the problem of vacuum energy and the foundations of nonperturbative string theory.

Chemical Reactions in Turbulent Mixing Flows

DTIC Science & Technology

1992-07-01

Chemically-Reacting, Gas-Phase Turbulent Jets (Gilbrech 1991), that explored Reynolds number effects on turbulent flame length and the influence of...and asymptotes to a constant value beyond the flame tip. The main result of the work is that the flame length , as estimated from the temperature...8217. Specifically, the normalized flame length Lf/d* displays a linear dependence on the stoichiometric mixture ratio 0, with a slope that decreases from Re "• 1.0

Association of Bruch's membrane opening and optic disc morphology to axial length and visual field defects in eyes with primary open-angle glaucoma.

PubMed

Nakanishi, Hideo; Suda, Kenji; Yoshikawa, Munemitsu; Akagi, Tadamichi; Kameda, Takanori; Ikeda, Hanako Ohashi; Yokota, Satoshi; Kurimoto, Yasuo; Tsujikawa, Akitaka

2018-03-01

To examine the morphology of Bruch's membrane opening (BMO), optic disc, and peripapillary atrophy (PPA) by scanning laser ophthalmoscopy (SLO) and spectral-domain optical coherence tomography (SD-OCT), and to determine their association with the axial length and visual field defects. This was a cross-sectional study of 94 eyes of 56 subjects; 77 eyes were diagnosed with primary open-angle glaucoma and 17 eyes as normal. The margins of the optic disc were determined in the SLO images, and that of the BMO in the SD-OCT images. The ovality and area of the BMO and the optic disc were measured. The beta and gamma-PPA areas were also measured. The association of each parameter with the axial length and the mean deviation (MD) of the visual field tests was determined by generalized estimating equations (GEEs). The optic disc ovality was associated with the axial length and the MD (β = -0.47, P = 7.6 × 10 -4 and β = 0.12, P = 0.040). The BMO ovality was not significantly associated with the axial length and the MD. The BMO area was associated with the axial length (β = 0.30, P = 0.029). A larger BMO area was associated with a thinner BMO-based neuroretinal rim width (BMO-MRW) after adjustments for the MD (β = -0.30, P = 2.1 × 10 -4 ). The beta- and gamma-PPA areas were associated with the axial length (β = 0.50, P = 7.4 × 10 -5 and β = 0.62, P = 4.2 × 10 -6 ). The optic disc ovality was associated with both the axial length and MD, whereas BMO ovality was not. Attention should be paid to the influence of the axial length-related enlargement of the BMO.

Scattering of electromagnetic wave by the layer with one-dimensional random inhomogeneities

NASA Astrophysics Data System (ADS)

Kogan, Lev; Zaboronkova, Tatiana; Grigoriev, Gennadii., IV.

A great deal of attention has been paid to the study of probability characteristics of electro-magnetic waves scattered by one-dimensional fluctuations of medium dielectric permittivity. However, the problem of a determination of a density of a probability and average intensity of the field inside the stochastically inhomogeneous medium with arbitrary extension of fluc-tuations has not been considered yet. It is the purpose of the present report to find and to analyze the indicated functions for the plane electromagnetic wave scattered by the layer with one-dimensional fluctuations of permittivity. We assumed that the length and the amplitude of individual fluctuations as well the interval between them are random quantities. All of indi-cated fluctuation parameters are supposed as independent random values possessing Gaussian distribution. We considered the stationary time cases both small-scale and large-scale rarefied inhomogeneities. Mathematically such problem can be reduced to the solution of integral Fred-holm equation of second kind for Hertz potential (U). Using the decomposition of the field into the series of multiply scattered waves we obtained the expression for a probability density of the field of the plane wave and determined the moments of the scattered field. We have shown that all odd moments of the centered field (U-¡U¿) are equal to zero and the even moments depend on the intensity. It was obtained that the probability density of the field possesses the Gaussian distribution. The average field is small compared with the standard fluctuation of scattered field for all considered cases of inhomogeneities. The value of average intensity of the field is an order of a standard of fluctuations of field intensity and drops with increases the inhomogeneities length in the case of small-scale inhomogeneities. The behavior of average intensity is more complicated in the case of large-scale medium inhomogeneities. The value of average intensity is the oscillating function versus the average fluctuations length if the standard of fluctuations of inhomogeneities length is greater then the wave length. When the standard of fluctuations of medium inhomogeneities extension is smaller then the wave length, the av-erage intensity value weakly depends from the average fluctuations extension. The obtained results may be used for analysis of the electromagnetic wave propagation into the media with the fluctuating parameters caused by such factors as leafs of trees, cumulus, internal gravity waves with a chaotic phase and etc. Acknowledgment: This work was supported by the Russian Foundation for Basic Research (projects 08-02-97026 and 09-05-00450).

Changes in markers of oxidative stress and DNA damage in human visceral adipose tissue from subjects with obesity and type 2 diabetes.

PubMed

Jones, D A; Prior, S L; Barry, J D; Caplin, S; Baxter, J N; Stephens, J W

2014-12-01

In the past 30 years, prevalence of obesity has almost trebled resulting in an increased incidence of type 2 diabetes mellitus and other co-morbidities. Visceral adipose tissue is believed to play a vital role, but underlying mechanisms remain unclear. Our aim was to investigate changes in markers of oxidative damage in human visceral adipose tissue to determine levels of oxidative burden that may be attributed to obesity and/or diabetes. Visceral adipose tissue samples from 61 subjects undergoing abdominal surgery grouped as lean, obese and obese with type 2 diabetes mellitus, were examined using 3 different markers of oxidative stress. Malondialdehyde (MDA) concentration was measured as a marker of lipid peroxidation, telomere length and Comet assay as markers of oxidative DNA damage. No significant difference in MDA concentration, telomere length and DNA damage was observed between groups, although longer telomere lengths were seen in the obese with diabetes group compared to the obese group (P<0.05). Lower MDA concentration and longer telomere length were seen in subjects with diabetes compared to those without (P<0.05). DNA damage, analysed via Comet assay, was significantly lower in subjects with diabetes compared to those without (P<0.05). A paradoxical decrease in oxidative stress and DNA damage was observed in samples from subjects with type 2 diabetes mellitus. Further work is required to investigate this further, however this phenomenon may be due to an up regulation of antioxidant defences in adipose tissue. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Experimental investigation on the effect of swirling flow on combustion characteristics and performance of solid fuel ramjet

NASA Astrophysics Data System (ADS)

Musa, Omer; Weixuan, Li; Xiong, Chen; Lunkun, Gong; Wenhe, Liao

2018-07-01

Solid-fuel ramjet converts thermal energy of combustion products to a forward thrust without using any moving parts. Normally, it uses air intake system to compress the incoming air without swirler. A new design of swirler has been proposed and used in the current work. In this paper, a series of firing tests have been carried out to investigate the impact of using swirl flow on regression rate, combustion characteristics, and performance of solid-fuel ramjet engines. The influences of swirl intensity, solid fuel port diameter, and combustor length were studied and varied independently. A new technique for determining the time and space averaged regression rate of high-density polyethylene solid fuel surface after experiments has been proposed based on the laser scan technique. A code has been developed to reconstruct the data from the scanner and then used to obtain the three-dimensional distribution of the regression rate. It is shown that increasing swirl number increases regression rate, thrust, and characteristic velocity, and, decreases air-fuel ratio, corner recirculation zone length, and specific impulse. Using swirl flow enhances the flame stability meanwhile negatively affected on ignition process and specific impulse. Although a significant reduction of combustion chamber length can be achieved when swirl flow is used. Power fitting correlation for average regression rate was developed taking into account the influence of swirl number. Furthermore, varying port diameter and combustor length were found to have influences on regression rate, combustion characteristics and performance of solid-fuel ramjet.

Large-scale evidence of dependency length minimization in 37 languages

PubMed Central

Futrell, Richard; Mahowald, Kyle; Gibson, Edward

2015-01-01

Explaining the variation between human languages and the constraints on that variation is a core goal of linguistics. In the last 20 y, it has been claimed that many striking universals of cross-linguistic variation follow from a hypothetical principle that dependency length—the distance between syntactically related words in a sentence—is minimized. Various models of human sentence production and comprehension predict that long dependencies are difficult or inefficient to process; minimizing dependency length thus enables effective communication without incurring processing difficulty. However, despite widespread application of this idea in theoretical, empirical, and practical work, there is not yet large-scale evidence that dependency length is actually minimized in real utterances across many languages; previous work has focused either on a small number of languages or on limited kinds of data about each language. Here, using parsed corpora of 37 diverse languages, we show that overall dependency lengths for all languages are shorter than conservative random baselines. The results strongly suggest that dependency length minimization is a universal quantitative property of human languages and support explanations of linguistic variation in terms of general properties of human information processing. PMID:26240370

The effect of cervical preflaring using different rotary nickel-titanium systems on the accuracy of apical file size determination.

PubMed

Tennert, Christian; Herbert, Josef; Altenburger, Markus Jörg; Wrbas, Karl-Thomas

2010-10-01

An exact determination of the apical root canal diameter is crucial for correct cleaning and shaping of a root canal. The aim of this study was to investigate the discrepancies of the initial apical root canal diameter and the diameter that is measured by the initial apical file (IAF) after cervical flaring using current rotary nickel-titanium systems. Mesiobuccal canals of 40 extracted mandibular molars were randomly assigned to four groups. In the first group, root canals were not flared. Root canals of the other groups were preflared using FlexMaster (VDW, Munich, Germany), ProTaper (Dentsply, Konstanz, Germany), or RaCe (FKG Dentaire, Genf, Switzerland) instruments. The tooth length was determined by inserting an ISO 06 K-file to the apical foramen. The working length (WL) was set 1 mm short of the apical foramen. File sizes were increased after binding sensation was felt at the WL. Transversal sections of the WL regions were examined under stereomicroscope, and the diameter of the root canal and the IAF at WL were assessed. Canals preflared with RaCe instruments had the lowest discrepancy between the apical root canal diameter and the IAF diameter (15.7 ± 9.7 μm) followed by ProTaper (22.2 ± 11.0 μm) and FlexMaster (35.0 ± 17.2 μm). Preflaring of root canals prevents underestimation of the actual apical root canal diameter. The type of instruments used for preflaring show differences on the accuracy of IAF determination. Preflaring with larger tapered instruments leads to a more accurate apical sizing, and this information is crucial concerning the appropriate final diameter for complete apical shaping. Copyright © 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Mixed-mode stress intensity factors for kink cracks with finite kink length loaded in tension and bending: application to dentin and enamel.

PubMed

Bechtle, Sabine; Fett, Theo; Rizzi, Gabriele; Habelitz, Stefan; Schneider, Gerold A

2010-05-01

Fracture toughness resistance curves describe a material's resistance against crack propagation. These curves are often used to characterize biomaterials like bone, nacre or dentin as these materials commonly exhibit a pronounced increase in fracture toughness with crack extension due to co-acting mechanisms such as crack bridging, crack deflection and microcracking. The knowledge of appropriate stress intensity factors which depend on the sample and crack geometry is essential for determining these curves. For the dental biomaterials enamel and dentin it was observed that, under bending and tensile loading, crack propagation occurs under certain constant angles to the initial notch direction during testing procedures used for fracture resistance curve determination. For this special crack geometry (a kink crack of finite length in a finite body) appropriate geometric function solutions are missing. Hence, we present in this study new mixed-mode stress intensity factors for kink cracks with finite kink length within samples of finite dimensions for two loading cases (tension and bending) which were derived from a combination of mixed-mode stress intensity factors of kink cracks with infinitely small kinks and of slant cracks. These results were further applied to determine the fracture resistance curves of enamel and dentin by testing single edge notched bending (SENB) specimens. It was found that kink cracks with finite kink length exhibit identical stress fields to slant cracks as soon as the kink length exceeds 0.15 times the initial straight crack or notch length. The use of stress intensity factor solutions for infinitely small kink cracks for the determination of dentin fracture resistance curves (as was done by other researchers) leads to an overestimation of dentin's fracture resistance of up to 30%. Copyright 2010 Elsevier Ltd. All rights reserved.

Impact of a Safe Resident Handling Program in Nursing Homes on Return-to-Work and Re-injury Outcomes Following Work Injury.

PubMed

Kurowski, Alicia; Pransky, Glenn; Punnett, Laura

2018-05-21

Purpose This study examined the impact of a Safe Resident Handling Program (SRHP) on length of disability and re-injury, following work-related injuries of nursing home workers. Resident handling-related injuries and back injuries were of particular interest. Methods A large national nursing home corporation introduced a SRHP followed by three years of training for 136 centers. Lost-time workers' compensation claims (3 years pre-SRHP and 6 years post-SRHP) were evaluated. For each claim, length of first episode of disability and recurrence of disabling injury were evaluated over time. Differences were assessed using Chi square analyses and a generalized linear model, and "avoided" costs were projected. Results The SRHP had no impact on length of disability, but did appear to significantly reduce the rate of recurrence among resident handling-related injuries. As indemnity and medical costs were three times higher for claimants with recurrent disabling injuries, the SRHP resulted in significant "avoided" costs due to "avoided" recurrence. Conclusions In addition to reducing overall injury rates, SRHPs appear to improve long-term return-to-work success by reducing the rate of recurrent disabling injuries resulting in work disability. In this study, the impact was sustained over years, even after a formal training and implementation program ended. Since back pain is inherently a recurrent condition, results suggest that SRHPs help workers remain at work and return-to-work.

Branch length estimation and divergence dating: estimates of error in Bayesian and maximum likelihood frameworks.

PubMed

Schwartz, Rachel S; Mueller, Rachel L

2010-01-11

Estimates of divergence dates between species improve our understanding of processes ranging from nucleotide substitution to speciation. Such estimates are frequently based on molecular genetic differences between species; therefore, they rely on accurate estimates of the number of such differences (i.e. substitutions per site, measured as branch length on phylogenies). We used simulations to determine the effects of dataset size, branch length heterogeneity, branch depth, and analytical framework on branch length estimation across a range of branch lengths. We then reanalyzed an empirical dataset for plethodontid salamanders to determine how inaccurate branch length estimation can affect estimates of divergence dates. The accuracy of branch length estimation varied with branch length, dataset size (both number of taxa and sites), branch length heterogeneity, branch depth, dataset complexity, and analytical framework. For simple phylogenies analyzed in a Bayesian framework, branches were increasingly underestimated as branch length increased; in a maximum likelihood framework, longer branch lengths were somewhat overestimated. Longer datasets improved estimates in both frameworks; however, when the number of taxa was increased, estimation accuracy for deeper branches was less than for tip branches. Increasing the complexity of the dataset produced more misestimated branches in a Bayesian framework; however, in an ML framework, more branches were estimated more accurately. Using ML branch length estimates to re-estimate plethodontid salamander divergence dates generally resulted in an increase in the estimated age of older nodes and a decrease in the estimated age of younger nodes. Branch lengths are misestimated in both statistical frameworks for simulations of simple datasets. However, for complex datasets, length estimates are quite accurate in ML (even for short datasets), whereas few branches are estimated accurately in a Bayesian framework. Our reanalysis of empirical data demonstrates the magnitude of effects of Bayesian branch length misestimation on divergence date estimates. Because the length of branches for empirical datasets can be estimated most reliably in an ML framework when branches are <1 substitution/site and datasets are > or =1 kb, we suggest that divergence date estimates using datasets, branch lengths, and/or analytical techniques that fall outside of these parameters should be interpreted with caution.

Timing matters: length of leave and working mothers' daily reentry regrets.

PubMed

Wiese, Bettina S; Ritter, Johannes O

2012-11-01

Dealing with developmental tasks in work and family domains is an important challenge for young and middle-aged adults. We investigated a transition that has evolved into a normative task for women, namely, the retransition back to paid work following maternity leave. In a diary study with 149 mothers who had just returned to work, we examined the daily experienced regrets concerning this return. In addition to personal resources (i.e., emotional stability, feeling prepared for the transition) and financial requirements needed to return to work, daily experienced family stress predicted decisional regrets. Moreover, our results suggest that leave length is related to psychological resilience in the face of day-to-day stress experiences: Late returners reported fewer regrets in general and were unaffected by daily family stress. Return-to-work regrets, in turn, were predictive of withdrawal intentions. This underlines the relevancy of the timing of the transition back to work in terms of successful development during this life phase.

Nurses' shift length and overtime working in 12 European countries: the association with perceived quality of care and patient safety.

PubMed

Griffiths, Peter; Dall'Ora, Chiara; Simon, Michael; Ball, Jane; Lindqvist, Rikard; Rafferty, Anne-Marie; Schoonhoven, Lisette; Tishelman, Carol; Aiken, Linda H

2014-11-01

Despite concerns as to whether nurses can perform reliably and effectively when working longer shifts, a pattern of two 12- to 13-hour shifts per day is becoming common in many hospitals to reduce shift to shift handovers, staffing overlap, and hence costs. To describe shift patterns of European nurses and investigate whether shift length and working beyond contracted hours (overtime) is associated with nurse-reported care quality, safety, and care left undone. Cross-sectional survey of 31,627 registered nurses in general medical/surgical units within 488 hospitals across 12 European countries. A total of 50% of nurses worked shifts of ≤ 8 hours, but 15% worked ≥ 12 hours. Typical shift length varied between countries and within some countries. Nurses working for ≥ 12 hours were more likely to report poor or failing patient safety [odds ratio (OR)=1.41; 95% confidence interval (CI), 1.13-1.76], poor/fair quality of care (OR=1.30; 95% CI, 1.10-1.53), and more care activities left undone (RR=1.13; 95% CI, 1.09-1.16). Working overtime was also associated with reports of poor or failing patient safety (OR=1.67; 95% CI, 1.51-1.86), poor/fair quality of care (OR=1.32; 95% CI, 1.23-1.42), and more care left undone (RR=1.29; 95% CI, 1.27-1.31). European registered nurses working shifts of ≥ 12 hours and those working overtime report lower quality and safety and more care left undone. Policies to adopt a 12-hour nursing shift pattern should proceed with caution. Use of overtime working to mitigate staffing shortages or increase flexibility may also incur additional risk to quality.

Nurses’ Shift Length and Overtime Working in 12 European Countries

PubMed Central

Dall’Ora, Chiara; Simon, Michael; Ball, Jane; Lindqvist, Rikard; Rafferty, Anne-Marie; Schoonhoven, Lisette; Tishelman, Carol; Aiken, Linda H.

2014-01-01

Background: Despite concerns as to whether nurses can perform reliably and effectively when working longer shifts, a pattern of two 12- to 13-hour shifts per day is becoming common in many hospitals to reduce shift to shift handovers, staffing overlap, and hence costs. Objectives: To describe shift patterns of European nurses and investigate whether shift length and working beyond contracted hours (overtime) is associated with nurse-reported care quality, safety, and care left undone. Methods: Cross-sectional survey of 31,627 registered nurses in general medical/surgical units within 488 hospitals across 12 European countries. Results: A total of 50% of nurses worked shifts of ≤8 hours, but 15% worked ≥12 hours. Typical shift length varied between countries and within some countries. Nurses working for ≥12 hours were more likely to report poor or failing patient safety [odds ratio (OR)=1.41; 95% confidence interval (CI), 1.13–1.76], poor/fair quality of care (OR=1.30; 95% CI, 1.10–1.53), and more care activities left undone (RR=1.13; 95% CI, 1.09–1.16). Working overtime was also associated with reports of poor or failing patient safety (OR=1.67; 95% CI, 1.51–1.86), poor/fair quality of care (OR=1.32; 95% CI, 1.23–1.42), and more care left undone (RR=1.29; 95% CI, 1.27–1.31). Conclusions: European registered nurses working shifts of ≥12 hours and those working overtime report lower quality and safety and more care left undone. Policies to adopt a 12-hour nursing shift pattern should proceed with caution. Use of overtime working to mitigate staffing shortages or increase flexibility may also incur additional risk to quality. PMID:25226543

Stretching single atom contacts at multiple subatomic step-length.

PubMed

Wei, Yi-Min; Liang, Jing-Hong; Chen, Zhao-Bin; Zhou, Xiao-Shun; Mao, Bing-Wei; Oviedo, Oscar A; Leiva, Ezequiel P M

2013-08-14

This work describes jump-to-contact STM-break junction experiments leading to novel statistical distribution of last-step length associated with conductance of a single atom contact. Last-step length histograms are observed with up to five for Fe and three for Cu peaks at integral multiples close to 0.075 nm, a subatomic distance. A model is proposed in terms of gliding from a fcc hollow-site to a hcp hollow-site of adjacent atomic planes at 1/3 regular layer spacing along with tip stretching to account for the multiple subatomic step-length behavior.

Predictors of Spousal Support for the Work Commitments of Husbands.

ERIC Educational Resources Information Center

Pittman, Joe F.; Orthner, Dennis K.

1988-01-01

Examined antecedents of spousal support of husbands' work commitment from perspective of wives. Found spousal support influenced directly only by satisfaction with quality of life made possible by local work organization and length of involvement with organization. Marital and social adjustment, and perceptions of husband's work environment…

Thick lens chromatic effective focal length variation versus bending

NASA Astrophysics Data System (ADS)

Sparrold, Scott

2017-11-01

Longitudinal chromatic aberration (LCA) can limit the optical performance in refractive optical systems. Understanding a singlet's chromatic change of effective focal leads to insights and methods to control LCA. Long established, first order theory, shows the chromatic change in focal length for a zero thickness lens is proportional to it's focal length divided by the lens V number or inverse dispersion. This work presents the derivation of an equation for a thick singlet's chromatic change in effective focal length as a function of center thickness, t, dispersion, V, index of refraction, n, and the Coddington shape factor, K. A plot of bending versus chromatic focal length variation is presented. Lens thickness does not influence chromatic variation of effective focal length for a convex plano or plano convex lens. A lens's center thickness'influence on chromatic focal length variation is more pronounced for lower indices of refraction.

Multi-scale mechanics of granular solids from grain-resolved X-ray measurements

NASA Astrophysics Data System (ADS)

Hurley, R. C.; Hall, S. A.; Wright, J. P.

2017-11-01

This work discusses an experimental technique for studying the mechanics of three-dimensional (3D) granular solids. The approach combines 3D X-ray diffraction and X-ray computed tomography to measure grain-resolved strains, kinematics and contact fabric in the bulk of a granular solid, from which continuum strains, grain stresses, interparticle forces and coarse-grained elasto-plastic moduli can be determined. We demonstrate the experimental approach and analysis of selected results on a sample of 1099 stiff, frictional grains undergoing multiple uniaxial compression cycles. We investigate the inter-particle force network, elasto-plastic moduli and associated length scales, reversibility of mechanical responses during cyclic loading, the statistics of microscopic responses and microstructure-property relationships. This work serves to highlight both the fundamental insight into granular mechanics that is furnished by combined X-ray measurements and describes future directions in the field of granular materials that can be pursued with such approaches.

Reflections on the Journal of Applied Psychology for 1989 to 1994: Changes in major research themes and practices over 25 years.

PubMed

Schmitt, Neal

2017-03-01

Informal observations concerning journal content indicates that research investigating organizational behavior topics, including work on the structure of groups and determinants and consequences of group process along with the role of leadership in groups, has increased. Some topics have disappeared (e.g., job analysis, human factors, union-related work, consumer behavior) and others are declining (e.g., research methods, psychometrics). Perhaps the biggest change is in the length of articles, which is mostly a function of the inclusion of greater numbers of references and appendix material. Publishing some of this material in supplementary online materials is now current practice in the Journal of Applied Psychology. Concerns about use of journal space may also be entirely moot, if electronic publishing as opposed to print publishing becomes the norm. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Consumer and relationship factors associated with shared decision making in mental health consultations.

PubMed

Matthias, Marianne S; Fukui, Sadaaki; Kukla, Marina; Eliacin, Johanne; Bonfils, Kelsey A; Firmin, Ruth L; Oles, Sylwia K; Adams, Erin L; Collins, Linda A; Salyers, Michelle P

2014-12-01

This study explored the association between shared decision making and consumers' illness management skills and consumer-provider relationships. Medication management appointments for 79 consumers were audio recorded. Independent coders rated overall shared decision making, minimum level of shared decision making, and consumer-provider agreement for 63 clients whose visit included a treatment decision. Mental health diagnoses, medication adherence, patient activation, illness management, working alliance, and length of consumer-provider relationships were also assessed. Correlation analyses were used to determine relationships among measures. Overall shared decision making was not associated with any variables. Minimum levels of shared decision making were associated with higher scores on the bond subscale of the Working Alliance Inventory, indicating a higher degree of liking and trust, and with better medication adherence. Agreement was associated with shorter consumer-provider relationships. Consumer-provider relationships and shared decision making might have a more nuanced association than originally thought.

Sex differences in work-related traumatic brain injury due to assault.

PubMed

Mollayeva, Tatyana; Mollayeva, Shirin; Lewko, John; Colantonio, Angela

2016-06-16

To examine the etiology, prevalence and severity of assault-precipitated work-related traumatic brain injury (wrTBI) in Ontario, Canada through a sex lens. Cross-sectional study using data abstracted from the Ontario Workplace Safety and Insurance Board (WSIB) claims files in 2004. Descriptive analyses were conducted to determine the distribution of worker/employment/incident characteristics. Workplace physical violence that resulted in a TBI accounted for 6.6% percent of all TBI injury claims. Female workers, primarily in the health care/social services sector, accounted for over half of all TBIs. Most workers were assaulted by consumers/clients. Forty five percent of injuries occurred among workers with less than 3 years of employment. This paper identifies profiles of workers and workplaces for targeted preventive efforts. Future studies are needed to further address risk factors by sex and outcomes, such as length of disability and health care cost.

Telomere length in normal and neoplastic canine tissues.

PubMed

Cadile, Casey D; Kitchell, Barbara E; Newman, Rebecca G; Biller, Barbara J; Hetler, Elizabeth R

2007-12-01

To determine the mean telomere restriction fragment (TRF) length in normal and neoplastic canine tissues. 57 solid-tissue tumor specimens collected from client-owned dogs, 40 samples of normal tissue collected from 12 clinically normal dogs, and blood samples collected from 4 healthy blood donor dogs. Tumor specimens were collected from client-owned dogs during diagnostic or therapeutic procedures at the University of Illinois Veterinary Medical Teaching Hospital, whereas 40 normal tissue samples were collected from 12 control dogs. Telomere restriction fragment length was determined by use of an assay kit. A histologic diagnosis was provided for each tumor by personnel at the Veterinary Diagnostic Laboratory at the University of Illinois. Mean of the mean TRF length for 44 normal samples was 19.0 kilobases (kb; range, 15.4 to 21.4 kb), and the mean of the mean TRF length for 57 malignant tumors was 19.0 kb (range, 12.9 to 23.5 kb). Although the mean of the mean TRF length for tumors and normal tissues was identical, tumor samples had more variability in TRF length. Telomerase, which represents the main mechanism by which cancer cells achieve immortality, is an attractive therapeutic target. The ability to measure telomere length is crucial to monitoring the efficacy of telomerase inhibition. In contrast to many other mammalian species, the length of canine telomeres and the rate of telomeric DNA loss are similar to those reported in humans, making dogs a compelling choice for use in the study of human anti-telomerase strategies.

Structure-guided investigation of lipopolysaccharide O-antigen chain length regulators reveals regions critical for modal length control.

PubMed

Kalynych, Sergei; Ruan, Xiang; Valvano, Miguel A; Cygler, Miroslaw

2011-08-01

The O-antigen component of the lipopolysaccharide (LPS) represents a population of polysaccharide molecules with nonrandom (modal) chain length distribution. The number of the repeat O units in each individual O-antigen polymer depends on the Wzz chain length regulator, an inner membrane protein belonging to the polysaccharide copolymerase (PCP) family. Different Wzz proteins confer vastly different ranges of modal lengths (4 to >100 repeat units), despite having remarkably conserved structural folds. The molecular mechanism responsible for the selective preference for a certain number of O units is unknown. Guided by the three-dimensional structures of PCPs, we constructed a panel of chimeric molecules containing parts of two closely related Wzz proteins from Salmonella enterica and Shigella flexneri which confer different O-antigen chain length distributions. Analysis of the O-antigen length distribution imparted by each chimera revealed the region spanning amino acids 67 to 95 (region 67 to 95), region 200 to 255, and region 269 to 274 as primarily affecting the length distribution. We also showed that there is no synergy between these regions. In particular, region 269 to 274 also influenced chain length distribution mediated by two distantly related PCPs, WzzB and FepE. Furthermore, from the 3 regions uncovered in this study, region 269 to 274 appeared to be critical for the stability of the oligomeric form of Wzz, as determined by cross-linking experiments. Together, our data suggest that chain length determination depends on regions that likely contribute to stabilize a supramolecular complex.

Telomere tracking from birth to adulthood and residential traffic exposure.

PubMed

Bijnens, Esmée M; Zeegers, Maurice P; Derom, Catherine; Martens, Dries S; Gielen, Marij; Hageman, Geja J; Plusquin, Michelle; Thiery, Evert; Vlietinck, Robert; Nawrot, Tim S

2017-11-21

Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length. We investigated the importance of the early-life environment on both telomere tracking and adult telomere length. Among 184 twins of the East Flanders Prospective Twin Survey, telomere length in placental tissue and in buccal cells in young adulthood was measured. Residential addresses at birth and in young adulthood were geocoded and residential traffic and greenness exposure was determined. We investigated individual telomere tracking from birth over a 20 year period (mean age (SD), 22.6 (3.1) years) in association with residential exposure to traffic and greenness. Telomere length in placental tissue and in buccal cells in young adulthood correlated positively (r = 0.31, P < 0.0001). Persons with higher placental telomere length at birth were more likely to have a stronger downward shift in telomere ranking over life (P < 0.0001). Maternal residential traffic exposure correlated inversely with telomere length at birth. Independent of birth placental telomere length, telomere ranking between birth and young adulthood was negatively and significantly associated with residential traffic exposure at the birth address, while traffic exposure at the residential address at adult age was not associated with telomere length. Longitudinal evidence of telomere length tracking from birth to adulthood shows inverse associations of residential traffic exposure in association with telomere length at birth as well as accelerated telomere shortening in the first two decades of life.

Assessment of Equipment for the Determination of Nutrients in Marine Waters: A Case Study of the Microplate Technique

NASA Astrophysics Data System (ADS)

Aminot, A.

1996-09-01

An essential prerequisite for quality assurance of the colorimetric determination of nutrients in seawater is the use of suitable photometric equipment. Based on a knowledge of the optical characteristics of a particular system and the absorption coefficient of the analyte, a statistical approach can be used to predict the limit of detection and the limit of quantitation for a given determinand. The microplate technique, widely used for bioassays, is applicable to colorimetric analysis in general, and its use for the determination of nutrients in seawater has been suggested. This paper reports a theoretical assessment of its capabilities in this context and a practical check on its performance, taking the determination of nitrite in seawater as typical. The conclusion is that short optical path length and insufficient repeatability of the absorbance measurement render it unsuitable for the determination of the low concentrations generally encountered in marine work, with the possible exception of nitrate. The perceived advantage of high-speed analysis is a secondary consideration in the overall process of determining nutrients, and the microplate technique's small scale of operation is a definite disadvantage as this increases the risk of exposure to contamination problems, in comparison with conventional techniques.

Fiber length - fiber strength interrelationship for slash pine and its effect on pulp-sheet properties

Treesearch

F.F. Wangaard; George E. Woodson

1972-01-01

Based on a model developed for hardwood fiber strength-pulp property relationships, multiple-regression equations involving fiber strength, fiber length, and sheet density were determined to predict the properties of kraft pulps of slash pine (Pinus elliottii). Regressions for breaking length and burst factor accounted for 88 and 90 percent,...

Fiber length strength interrelationship for slash pine and its effect on pulp-sheet properties

Treesearch

F. G. Wangaard; G. E. Woodson

1973-01-01

Based on a model developed for hardwood fiber strength-pulp property relationships, multiple-regression equations involving fiber strength, fiber length, and sheet density were determined to predict the properties of kraft pulps of slash pine (Pinus elliottii). Regressions for breaking length and burst factor accounted for 88 and 90 percent,...

Statistical characteristics of excess fiber length in loose tubes of optical cable

NASA Astrophysics Data System (ADS)

Andreev, Vladimir A.; Gavryushin, Sergey A.; Popov, Boris V.; Popov, Victor B.; Vazhdaev, Michael A.

2017-04-01

This paper presents an analysis of the data measurements of excess fiber length in the loose tubes of optical cable during the post-process quality control of ready-made products. At determining estimates of numerical characteristics of excess fiber length method of results processing of direct multiple equally accurate measurements has been used. The results of experimental research of the excess length value at the manufacturing technology of loose tube remains constant.

Micro-computed Tomographic Analysis of Apical Microcracks before and after Root Canal Preparation by Hand, Rotary, and Reciprocating Instruments at Different Working Lengths.

PubMed

de Oliveira, Bruna Paloma; Câmara, Andréa Cruz; Duarte, Daniel Amancio; Heck, Richard John; Antonino, Antonio Celso Dantas; Aguiar, Carlos Menezes

2017-07-01

This study aimed to compare apical microcrack formation after root canal shaping by hand, rotary, and reciprocating files at different working lengths using micro-computed tomographic analysis. Sixty mandibular incisors were randomly divided into 6 experimental groups (n = 10) according to the systems and working lengths used for the root canal preparation: ProTaper Universal for Hand Use (Dentsply Maillefer, Ballaigues, Switzerland), HyFlex CM (Coltene-Whaledent, Allstetten, Switzerland), and Reciproc (VDW, Munich, Germany) files working at the apical foramen (AF) and 1 mm short of the AF (AF - 1 mm). The teeth were imaged with micro-computed tomographic scanning at an isotropic resolution of 14 μm before and after root canal preparation, and the cross-sectional images generated were assessed to detect microcracks in the apical portion of the roots. Overall, 17 (28.3%) specimens presented microcracks before instrumentation. Apical microcracks were present in 1 (ProTaper Universal for Hand Use), 3 (Hyflex CM), and 2 (Reciproc) specimens when the instrumentation terminated at the AF. When instrumentation was terminated at AF - 1 mm, apical microcracks were detected in 3 (ProTaper Universal for Hand Use) and 4 (Hyflex CM and Reciproc) specimens. All these microcracks detected after root canal preparation were already present before instrumentation, and no new apical microcrack was visualized. For all groups, the number of slices presenting microcracks after root canal preparation was the same as before canal preparation. Root canal shaping with ProTaper Universal for Hand Use, HyFlex CM, and Reciproc systems, regardless of the working length, did not produce apical microcracks. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Work ability of Chinese migrant workers: the influence of migration characteristics.

PubMed

Han, Lu; Shi, Leiyu; Lu, Liming; Ling, Li

2014-04-13

Migrant workers have become a vital labor supply to China's economy. Their migration process and work conditions may influence their health and work ability. The work ability of migrant workers in China and the influence of the migration process on work ability have not been explored extensively in previous studies. The objective of this study is to evaluate the association of migration characteristics and work-related factors with work ability among migrant workers in the Pearl River Delta. In this cross-sectional survey, the study population consisted of 907 migrant workers from ten factories in the Pearl River Delta who were exposed to organic solvents during work. The primary dependent variable of the study was work ability, measured by the Work Ability Index (WAI). The independent variables were individual characteristics, migration characteristics, and work-related factors. Logistic regression models were used to determine the influence of different factors on work ability and three dimensions of WAI. The result shows that among migration characteristics, social support was significantly associated with all three dimensions of the work ability index. Permanent migration intention and longer length of migration were negatively associated with the mental resource dimension of WAI. WAI was also influenced by individual and work-related factors. The findings of this study suggest that expanding migrants' social networks and social support systems in their work place or living community, (i.e. expanding the functions of labor unions) would be an effective way to improve migrant workers' work ability. Improving of migrant workers' physical and psychosocial related work environments would also increase their work ability.