A Mini-review on the Effect of Mini-implants on Contemporary Orthodontic Science

PubMed Central

Nosouhian, Saeid; Rismanchian, Mansour; Sabzian, Roya; Shadmehr, Elham; Badrian, Hamid; Davoudi, Amin

2015-01-01

The purpose of this literature review was to screen the valuable published articles regarding to the impacts of mini-implants on orthodontic science, briefly. The searching category was performed on the Pubmed using MeSH words such as “dental (mini) implants, orthodontic anchorage procedures, and orthodontic appliances.” After preliminary sketch, they were grouped as follow: Those evaluating (a) common appliances for providing orthodontic anchorage, (b) biomechanical details of mini-implants and their insertion, (c) clinical application of mini-implants for orthognathic treatments, (d) limitations and possible complications. In conclusion, mini-implant evolved the orthodontic treatment plans and compromised the required orthognathic surgery. Malocclusion treatment and pure orthodontic or orthopedic movements in the three-dimensions have become recently possible by using mini-implant to provide skeletal anchorage. PMID:26225113

A DISTANT RADIO MINI-HALO IN THE PHOENIX GALAXY CLUSTER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Weeren, R. J.; Andrade-Santos, F.; Forman, W. R.

We report the discovery of extended radio emission in the Phoenix cluster (SPT-CL J2344-4243, z = 0.596) with the Giant Metrewave Radio Telescope (GMRT) at 610 MHz. The diffuse emission extends over a region of at least 400-500 kpc and surrounds the central radio source of the Brightest Cluster Galaxy, but does not appear to be directly associated with it. We classify the diffuse emission as a radio mini-halo, making it the currently most distant mini-halo known. Radio mini-halos have been explained by synchrotron emitting particles re-accelerated via turbulence, possibly induced by gas sloshing generated from a minor merger event. Chandra observationsmore » show a non-concentric X-ray surface brightness distribution, which is consistent with this sloshing interpretation. The mini-halo has a flux density of 17 ± 5 mJy, resulting in a 1.4 GHz radio power of (10.4 ± 3.5) × 10{sup 24} W Hz{sup –1}. The combined cluster emission, which includes the central compact radio source, is also detected in a shallow GMRT 156 MHz observation and together with the 610 MHz data we compute a spectral index of –0.84 ± 0.12 for the overall cluster radio emission. Given that mini-halos typically have steeper radio spectra than cluster radio galaxies, this spectral index should be taken as an upper limit for the mini-halo.« less

Mini-screws success rates sufficient for orthodontic treatment.

PubMed

Stanford, Nicky

2011-01-01

Medline. Clinical trials of orthodontic mini-screws with a minimum of 30 cases providing data on the patient, mini-screw, surgery and loading available for correlation with the mini-screws' success rates in English or German were included. Data were extracted that correlated with the miniscrews' success rate: patient sex and age, screw length and diameter, method and location of placement, time and amount of loading. The statistical analyses were performed using SPSS software (version 13 for Mac OS X, SPSS, Chicago, Ill). Fourteen clinical trials (452 patients and 1519 screws) were included, with overall success rates ranging from 59.4% to 100%. The mean success rate was 83.6% ± 10.2%. Screw diameters of 1 to 1.1 mm yielded significantly lower success rates than those of 1.5 to 2.3 mm. One study reported significantly lower success rates for 6 mm vs 8 mm long mini-screws (72% vs 90%). Screw placement with or without a surgical flap showed contradictory results between studies. Three studies showed significantly higher success rates for maxillary than for mandibular screws. Loading and healing periods were not significant in the mini-screws' success rates. There was no influence of patient sex and one study found significantly greater success in patients over 30 years of age. All 14 articles described success rates sufficient for orthodontic treatment. Placement protocols varied markedly. Screws under 8 mm in length and 1.2 mm in diameter should be avoided. Immediate or early loading up to 200 cN was adequate and showed no significant influence on screw stability.

Mini-Rocket User Guide

DTIC Science & Technology

2007-08-01

26 8. ISTC Simulation Comparisons...Comparison c. Ground Range Comparison Figure 8. ISTC Simulation Comparisons Mini-Rocket User Guide REAL-WORLD COMPARISON 30 In particular, note...even though Mini-Rocket does not directly model the missile rigid body dynamics. The ISTC subsequently used Mini-Rocket as a driver to stimulate other

Dramatically Variable C IV Mini-Broad Absorption Line System in the Quasar HS 1603+3820

NASA Astrophysics Data System (ADS)

Misawa, T.; Eracleous, M.; Charlton, J. C.; Chartas, G.; Kashikawa, N.

2008-10-01

We observed the quasar HS 1603+3820 (z_{em} = 2.542, first discovered by Dobrzycki et al. 1996) six times over an interval of 4.2 yrs (1.2 yrs in the quasar rest frame) using the High Dispersion Spectrograph on Subaru telescope. The purpose was to study the mini-broad absorption line (mini-BAL; FWHM ˜ 1,000 km s^{-1}) that is blue-shifted from the quasar by ˜ 9,500 km s^{-1}. We found significant time variability, which supported the physical association of the mini-BAL gas with an outflow from the quasar. We have narrowed down the cause of the variability to two possible scenarios. We also used archival Chandra x-ray data to study the x-ray properties of this quasar. The results constrain the location of the absorbing gas relative to the overall outflow.

Psychometric properties of a sign language version of the Mini International Neuropsychiatric Interview (MINI).

PubMed

Øhre, Beate; Saltnes, Hege; von Tetzchner, Stephen; Falkum, Erik

2014-05-22

There is a need for psychiatric assessment instruments that enable reliable diagnoses in persons with hearing loss who have sign language as their primary language. The objective of this study was to assess the validity of the Norwegian Sign Language (NSL) version of the Mini International Neuropsychiatric Interview (MINI). The MINI was translated into NSL. Forty-one signing patients consecutively referred to two specialised psychiatric units were assessed with a diagnostic interview by clinical experts and with the MINI. Inter-rater reliability was assessed with Cohen's kappa and "observed agreement". There was 65% agreement between MINI diagnoses and clinical expert diagnoses. Kappa values indicated fair to moderate agreement, and observed agreement was above 76% for all diagnoses. The MINI diagnosed more co-morbid conditions than did the clinical expert interview (mean diagnoses: 1.9 versus 1.2). Kappa values indicated moderate to substantial agreement, and "observed agreement" was above 88%. The NSL version performs similarly to other MINI versions and demonstrates adequate reliability and validity as a diagnostic instrument for assessing mental disorders in persons who have sign language as their primary and preferred language.

Reliability and validity of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID).

PubMed

Sheehan, David V; Sheehan, Kathy H; Shytle, R Douglas; Janavs, Juris; Bannon, Yvonne; Rogers, Jamison E; Milo, Karen M; Stock, Saundra L; Wilkinson, Berney

2010-03-01

To investigate the concurrent validity and reliability of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID), a short structured diagnostic interview for DSM-IV and ICD-10 psychiatric disorders in children and adolescents. Participants were 226 children and adolescents (190 outpatients and 36 controls) aged 6 to 17 years. To assess the concurrent validity of the MINI-KID, participants were administered the MINI-KID and the Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version (K-SADS-PL) by blinded interviewers in a counterbalanced order on the same day. Participants also completed a self-rated measure of disability. In addition, interrater (n = 57) and test-retest (n = 83) reliability data (retest interval, 1-5 days) were collected, and agreement between the parent version of the MINI-KID and the standard MINI-KID (n = 140) was assessed. Data were collected between March 2004 and January 2008. Substantial to excellent MINI-KID to K-SADS-PL concordance was found for syndromal diagnoses of any mood disorder, any anxiety disorder, any substance use disorder, any ADHD or behavioral disorder, and any eating disorder (area under curve [AUC] = 0.81-0.96, kappa = 0.56-0.87). Results were more variable for psychotic disorder (AUC = 0.94, kappa = 0.41). Sensitivity was substantial (0.61-1.00) for 15/20 individual DSM-IV disorders. Specificity was excellent (0.81-1.00) for 18 disorders and substantial (> 0.73) for the remaining 2. The MINI-KID identified a median of 3 disorders per subject compared to 2 on the K-SADS-PL and took two-thirds less time to administer (34 vs 103 minutes). Interrater and test-retest kappas were substantial to almost perfect (0.64-1.00) for all individual MINI-KID disorders except dysthymia. Concordance of the parent version (MINI-KID-P) with the standard MINI-KID was good. The MINI-KID generates reliable and valid psychiatric diagnoses for children and

[Validation of the portuguese version of the Mini-Social Phobia Inventory (Mini-SPIN)].

PubMed

D'El Rey, Gustavo José Fonseca; Matos, Cláudia Wilmor

2009-01-01

Social phobia (also known as social anxiety disorder) is a severe mental disorder that brings distress and disability. The aim of this study was validate to the Portuguese language the Mini-Social Phobia Inventory (Mini-SPIN) in a populational sample. We performed a discriminative validity study of the Mini-SPIN in a sample of 644 subjects (Mini-SPIN positive group: n = 218 and control/negative group: n = 426) of a study of anxiety disorders' prevalence in the city of Santo André-SP. The Portuguese version of the Mini-SPIN (with score of 6 points, suggested in the original English version) demonstrated a sensitivity of 95.0%, specificity of 80.3%, positive predictive value of 52.8%, negative predictive value of 98.6% and incorrect classification rate of 16.9%. With score of 7 points, was observed an increase in the specificity and positive predictive value (88.6% and 62.7%), while the sensitivity and negative predictive value (84.8% and 96.2%) remained high. The Portuguese version of the Mini-SPIN showed satisfactory psychometric qualities in terms of discriminative validity. In this study, the cut-off of 7, was considered to be the most suitable to screening of the generalized social phobia.

Mini-RF Bistatic Observations of Lunar Crater Ejecta

NASA Astrophysics Data System (ADS)

Stickle, A. M.; Patterson, G. W.; Cahill, J. T.

2017-12-01

The Mini-RF radar onboard the Lunar Reconnaissance Orbiter (LRO) is currently operating in a bistatic configuration using the Goldstone DSS-13 and Arecibo Observatory as transmitters in X-band (4.2-cm) and S-band (12.6 cm), respectively. The Circular Polarization Ratio (CPR) is a typical product derived from backscattered microwave radiation that examines the scattering properties of the lunar surface, particularly the roughness of the surface on the order of the radar wavelength. Throughout the LRO extended mission, Mini-RF has targeted young craters on the lunar surface to examine the scattering properties of their ejecta blankets in both S- and X-band. Several observed craters and their ejecta blankets exhibit a clear coherent backscatter opposition effect at low bistatic (phase) angles. This opposition effect is consistent with optical studies of lunar soils done in the laboratory, but these observations are the first time this effect has been measured on the Moon at radar wavelengths. The style of the observed opposition effect differs between craters, which may indicate differences in ejecta fragment formation or emplacement. Differences in the CPR behavior as a function of bistatic angle may also provide opportunities for relative age dating between Copernican craters. Here, we examine the ejecta of nine Copernican and Eratosthenian aged craters in both S-band and X-band and document CPR characteristics as a function bistatic angle in order to test that hypothesis. The youngest craters observed by Mini-RF (e.g., Byrgius A (48 My), Kepler (635-1250 My)) exhibit a clear opposition effect, while older craters such as Hercules have a fairly flat response in CPR as a function of phase angle. Craters with ages between these two ends, e.g., Aristarchus, exhibit a weaker opposition response. Observing the scattering behavior of continuous ejecta blankets in multiple wavelengths may provide further information about the rate of breakdown of rocks of varying size to

INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF TECHNOLOGIES FOR MEASURING TRACE ELEMENTS IN SOIL AND SEDIMENT RIGAKU ZSX MINI 11 XRF ANALYZER

EPA Science Inventory

The Rigaku ZSX Mini II (ZSX Mini II) XRF Services x-ray fluorescence (XRF) analyzer was demon-strated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2...

Status of the MiniCLEAN dark matter experiment

NASA Astrophysics Data System (ADS)

Rielage, Keith

2009-10-01

MiniCLEAN utilizes over 400 kg of liquid cryogen to detect nuclear recoils from WIMP dark matter with a projected sensitivity of 2x10-45 cm^2 for a mass of 100 GeV. The liquid cryogen is interchangeable between argon and neon to study the A^2 dependence of the potential signal and examine backgrounds. MiniCLEAN utilizes a unique modular design with spherical geometry to maximize the light yield using cold photomultiplier tubes in a single-phase detector. Pulse shape discrimination techniques are used to separate nuclear recoil signals from electron recoil backgrounds. Particular attention is being paid to mitigating the backgrounds from contamination of surfaces by radon daughters during assembly. The design and assembly status of the experiment will be discussed. The projected timeline and future plans for staging the experiment at SNOLAB in Sudbury, Canada will be presented.

Neutrino-nucleus neutral current elastic interactions measurement in MiniBooNE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perevalov, Denis

2009-12-01

The MiniBooNE experiment at the Fermi National Accelerator Laboratory (Fermilab) was designed to search for v μ → v e neutrino oscillations at Δm 2 ~ 1 eV 2 using an intense neutrino flux with an average energy E v ~ 700 MeV. From 2002 to 2009 MiniBooNE has accumulated more than 1.0 x 10 21 protons on target (POT) in both neutrino and antineutrino modes. MiniBooNE provides a perfect platform for detailed measurements of exclusive and semiinclusive neutrino cross-sections, for which MiniBooNE has the largest samples of events up to date, such as neutral current elastic (NCE), neutral currentmore » π 0, charged current quasi-elastic (CCQE), charged current π +, and other channels. These measured cross-sections, in turn, allow to improve the knowledge of nucleon structure. This thesis is devoted to the study of NCE interactions. Neutrino-nucleus neutral current elastic scattering (vN → vN) accounts for about 18% of all neutrino interactions in MiniBooNE. Using a high-statistics, high purity sample of NCE interactions in MiniBooNE, the flux-averaged NCE differential cross-section has been measured and is being reported here. Further study of the NCE cross-section allowed for probing the structure of nuclei. The main interest in the NCE cross-section is that it may be sensitive to the strange quark contribution to the nucleon spin, Δs, this however requires a separation of NCE proton (vp → vp) from NCE neutron (vn → vn) events, which in general is a challenging task. MiniBooNE uses a Cherenkov detector, which imposes restrictions on the measured nucleon kinematic variables, mainly due to the impossibility to reconstruct the nucleon direction below the Cherenkov threshold. However, at kinetic energies above this threshold MiniBooNE is able to identify NCE proton events that do not experience final state interactions (FSI). These events were used for the Δs measurement. In this thesis MiniBooNE reports the NCE (n+p) cross-section, the measurement of the

Neutrino-nucleus neutral current elastic interactions measurement in MiniBooNE

NASA Astrophysics Data System (ADS)

Perevalov, Denis

The MiniBooNE experiment at the Fermi National Accelerator Laboratory (Fermilab) was designed to search for numu → nu e neutrino oscillations at Deltam 2 ˜ 1 eV2 using an intense neutrino flux with an average energy Enu ˜ 700 MeV. From 2002 to 2009 MiniBooNE has accumulated more than 1.0x1021 protons on target (POT) in both neutrino and antineutrino modes. MiniBooNE provides a perfect platform for detailed measurements of exclusive and semi-inclusive neutrino cross-sections, for which MiniBooNE has the largest samples of events up to date, such as neutral current elastic (NCE), neutral current pi 0, charged current quasi-elastic (CCQE), charged current pi +, and other channels. These measured cross-sections, in turn, allow to improve the knowledge of nucleon structure. This thesis is devoted to the study of NCE interactions. Neutrino-nucleus neutral current elastic scattering (nuN → nu N) accounts for about 18% of all neutrino interactions in MiniBooNE. Using a high-statistics, high purity sample of NCE interactions in MiniBooNE, the flux-averaged NCE differential cross-section has been measured and is being reported here. Further study of the NCE cross-section allowed for probing the structure of nuclei. The main interest in the NCE cross-section is that it may be sensitive to the strange quark contribution to the nucleon spin, Deltas, this however requires a separation of NCE proton (nup → nu p) from NCE neutron (nun → nun ) events, which in general is a challenging task. MiniBooNE uses a Cherenkov detector, which imposes restrictions on the measured nucleon kinematic variables, mainly due to the impossibility to reconstruct the nucleon direction below the Cherenkov threshold. However, at kinetic energies above this threshold MiniBooNE is able to identify NCE proton events that do not experience final state interactions (FSI). These events were used for the Deltas measurement. In this thesis MiniBooNE reports the NCE (n+p) cross-section, the measurement

Haze production in the atmospheres of super-Earths and mini-Neptunes: Insight from PHAZER lab

NASA Astrophysics Data System (ADS)

Horst, Sarah; He, Chao; Kempton, Eliza; Moses, Julianne I.; Vuitton, Veronique; Lewis, Nikole

2017-10-01

Super-Earths and mini-Neptunes (~1.2-3 Earth radii) comprise a large fraction of planets in the universe and TESS (Transiting Exoplanet Survey Satellite) will increase the number that are amenable to atmospheric characterization with observatories like JWST (James Webb Space Telescope). These atmospheres should span a large range of temperature and atmospheric composition phase space, with no solar system analogues. Interpretation of current and future atmospheric observations of super-Earths and mini-Neptunes requires additional knowledge about atmospheric chemistry and photochemical haze production. We have experimentally investigated haze formation for H2, H2O, and CO2 dominated atmospheres (100x, 1000x, and 10000x solar metallicity) for a range of temperatures (300 K, 400 K, and 600 K) using the PHAZER (Planetary Haze Research) experiment at Johns Hopkins University. This is a necessary step in understanding which, if any, super-Earths and mini-Neptunes possess the conditions required for efficient production of photochemical haze in their atmospheres. We find that the production rates vary over a few orders of magnitudes with some higher than our nominal Titan experiments. We therefore expect that planets in this temperature and atmospheric composition phase space will exhibit a range of particle concentrations and some may be as hazy as Titan.

MINI PCNL in a Pediatric Population

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wah, Tze M., E-mail: Tze.Wah@leedsth.nhs.uk; Kidger, Lizi; Kennish, Steven

2013-02-15

We report our initial experience of MINI percutaneous nephrolithotomy (PCNL) in a pediatric population using a miniature nephroscope through a 16F metal access sheath. All pediatric patients who underwent PCNL from August 2007 to September 2010 using a 14F miniature nephroscope through a 16F metal access sheath for renal stone extraction were evaluated. Patients' demographic details, procedural information, and posttreatment outcomes were prospectively documented. A total of 23 MINI PCNLs were performed on 23 kidneys of 12 patients whose ages ranged from 1.6 to 14.6 years. The median stone burden was 3.44 cm{sup 2}, and there were 11 'Staghorn' stones.more » The procedure was primary via a single puncture in 19 kidneys and secondary using a preexisting nephrostomy tract in 4 kidneys. Access was successful in all primary and two secondary cases, for a total of success rate of 91.3%. Stones were fragmented using a Holmium laser and/or lithoclast, and fragments were irrigated or sequentially removed by various stone grasping devices. The mean procedural X-ray screening time and total stone extraction period were 4.5 and 109.4 min, respectively. The primary stone free rate was 83.6 %, which increased to 90.5 % after treating the residual fragments. Postoperative hydrothorax developed in one patient, which required a chest drain. Symptoms of chest infection and positive urine culture were detected in one and two patients, respectively. Our initial experience supports previous reports that MINI PCNL is safe and effective for the management of renal stones in children.« less

The Galactic Centre Mini-Spiral in the MM-Regime

NASA Technical Reports Server (NTRS)

Kunneriath, D.; Eckart, A.; Vogel, S. N.; Teuben, P.; Muzic, I.; Schoedel, R.; Garcia-Marin, M.; Moultaka, J.; Staguhn, J.; Straubmeier, C.;

miniTri Mantevo miniapp v. 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berry, Johathan; Stark, Dylan; Wolf, Michael

2016-02-02

miniTri is a miniapplication developed as part of the Mantevo project. Given a graph, miniTri enumerates all triangles in this graph and computes a metric for each triangle based on the triangle edge and vertex degree. The output of miniTri is a summary of this metric. miniTri mimics the computational requirements of an important set of data science applications. Several approaches to this problem are included in the miniTri software.

Effects of MeJA on Arabidopsis metabolome under endogenous JA deficiency

NASA Astrophysics Data System (ADS)

Cao, Jingjing; Li, Mengya; Chen, Jian; Liu, Pei; Li, Zhen

2016-11-01

Jasmonates (JAs) play important roles in plant growth, development and defense. Comprehensive metabolomics profiling of plants under JA treatment provides insights into the interaction and regulation network of plant hormones. Here we applied high resolution mass spectrometry based metabolomics approach on Arabidopsis wild type and JA synthesis deficiency mutant opr3. The effects of exogenous MeJA treatment on the metabolites of opr3 were investigated. More than 10000 ion signals were detected and more than 2000 signals showed significant variation in different genotypes and treatment groups. Multivariate statistic analyses (PCA and PLS-DA) were performed and a differential compound library containing 174 metabolites with high resolution precursor ion-product ions pairs was obtained. Classification and pathway analysis of 109 identified compounds in this library showed that glucosinolates and tryptophan metabolism, amino acids and small peptides metabolism, lipid metabolism, especially fatty acyls metabolism, were impacted by endogenous JA deficiency and exogenous MeJA treatment. These results were further verified by quantitative reverse transcription PCR (RT-qPCR) analysis of 21 related genes involved in the metabolism of glucosinolates, tryptophan and α-linolenic acid pathways. The results would greatly enhance our understanding of the biological functions of JA.

Psychometric Evaluation of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID).

PubMed

Duncan, Laura; Georgiades, Kathy; Wang, Li; Van Lieshout, Ryan J; MacMillan, Harriet L; Ferro, Mark A; Lipman, Ellen L; Szatmari, Peter; Bennett, Kathryn; Kata, Anna; Janus, Magdalena; Boyle, Michael H

2017-12-04

The goals of the study were to examine test-retest reliability, informant agreement and convergent and discriminant validity of nine DSM-IV-TR psychiatric disorders classified by parent and youth versions of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID). Using samples drawn from the general population and child mental health outpatient clinics, 283 youth aged 9 to 18 years and their parents separately completed the MINI-KID with trained lay interviewers on two occasions 7 to 14 days apart. Test-retest reliability estimates based on kappa (κ) went from 0.33 to 0.79 across disorders, samples and informants. Parent-youth agreement on disorders was low (average κ = 0.20). Confirmatory factor analysis provided evidence supporting convergent and discriminant validity. The MINI-KID disorder classifications yielded estimates of test-retest reliability and validity comparable to other standardized diagnostic interviews in both general population and clinic samples. These findings, in addition to the brevity and low administration cost, make the MINI-KID a good candidate for use in epidemiological research and clinical practice. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

The Formation of Mini-Neptunes

NASA Astrophysics Data System (ADS)

Venturini, Julia; Helled, Ravit

2017-10-01

Mini-Neptunes seem to be common planets. In this work we investigate the possible formation histories and predicted occurrence rates of mini-Neptunes, assuming that the planets form beyond the iceline. We consider pebble and planetesimal accretion accounting for envelope enrichment and two different opacity conditions. We find that the formation of mini-Neptunes is a relatively frequent output when envelope enrichment by volatiles is included, and that there is a “sweet spot” for mini-Neptune formation with a relatively low solid accretion rate of ˜10-6 M ⊕ yr-1. This rate is typical for low/intermediate-mass protoplanetary disks and/or disks with low metallicities. With pebble accretion, envelope enrichment and high opacity favor the formation of mini-Neptunes, with more efficient formation at large semimajor axes (˜30 au) and low disk viscosities. For planetesimal accretion, such planets can also form without enrichment, with the opacity being a key aspect in the growth history and favorable formation location. Finally, we show that the formation of Neptune-like planets remains a challenge for planet formation theories.

The mini-CIDEX GC/IMS: Analysis of cometary ice and dust

NASA Technical Reports Server (NTRS)

Kojiro, Daniel R.; Carle, Glenn C.; Humphry, Donald E.; Shao, Maxine; Takeuchi, Nori

1995-01-01

Comets are recognized as among the most scientifically important objects in the solar system. They are presumed relics of the early primitive material in the solar nebula and are believed to have provided a general enrichment of volatiles to the inner solar system. The Cometary Coma Chemical Composition (C4) Mission, a proposed Discovery-Class Mission, will analyze materials released into the coma, providing information leading to the understanding of the chemical composition and make-up of the cometary nucleus. As one of two scientific instruments in the C4 spacecraft, an advanced and streamlined version of the Cometary Ice and Dust Experiment (CIDEX), a mini-CIDEX, will employ an X-Ray Fluorescence (XRF) spectrometer to determine bulk elemental composition of cometary dust grains and a Gas Chromatograph/Ion Mobility Spectrometer (GC/IMS) for determination of the molecular composition of dust and ices following stepwise pyrolysis and combustion. A description of the mini-CIDEX IMS will be provided as well as data from analyses conducted using the mini-CIDEX breadboard instrument.

A Mini-BAL Outflow at 900 pc from the Central Source: VLT/X-shooter Observations

NASA Astrophysics Data System (ADS)

Xu, Xinfeng; Arav, Nahum; Miller, Timothy; Benn, Chris

2018-05-01

We determine the physical conditions and location of the outflow material seen in the mini-BAL quasar SDSS J1111+1437 (z = 2.138). These results are based on the analysis of a high S/N, medium-resolution VLT/X-shooter spectrum. The main outflow component spans the velocity range ‑1500 to ‑3000 km s‑1 and has detected absorption troughs from both high-ionization species: C IV, N V, O VI, Si IV, P V, and S IV; and low-ionization species: H I, C II, Mg II, Al II, Al III, Si II, and Si III. Measurements of these troughs allow us to derive an accurate photoionization solution for this absorption component: a hydrogen column density, {log}({N}{{H}})={21.47}-0.27+0.21 cm‑2 and ionization parameter, {log}({U}{{H}})=-{1.23}-0.25+0.20. Troughs produced from the ground and excited states of S IV combined with the derived {U}{{H}} value allow us to determine an electron number density of {log}({n}{{e}})={3.62}-0.11+0.09 cm‑3 and to obtain the distance of the ionized gas from the central source: R={880}-260+210 pc.

[Bone remodeling and modeling/mini-modeling.

PubMed

Hasegawa, Tomoka; Amizuka, Norio

Modeling, adapting structures to loading by changing bone size and shapes, often takes place in bone of the fetal and developmental stages, while bone remodeling-replacement of old bone into new bone-is predominant in the adult stage. Modeling can be divided into macro-modeling(macroscopic modeling)and mini-modeling(microscopic modeling). In the cellular process of mini-modeling, unlike bone remodeling, bone lining cells, i.e., resting flattened osteoblasts covering bone surfaces will become active form of osteoblasts, and then, deposit new bone onto the old bone without mediating osteoclastic bone resorption. Among the drugs for osteoporotic treatment, eldecalcitol(a vitamin D3 analog)and teriparatide(human PTH[1-34])could show mini-modeling based bone formation. Histologically, mature, active form of osteoblasts are localized on the new bone induced by mini-modeling, however, only a few cell layer of preosteoblasts are formed over the newly-formed bone, and accordingly, few osteoclasts are present in the region of mini-modeling. In this review, histological characteristics of bone remodeling and modeling including mini-modeling will be introduced.

A DNA mini-barcode for land plants.

PubMed

Little, Damon P

2014-05-01

Small portions of the barcode region - mini-barcodes - may be used in place of full-length barcodes to overcome DNA degradation for samples with poor DNA preservation. 591,491,286 rbcL mini-barcode primer combinations were electronically evaluated for PCR universality, and two novel highly universal sets of priming sites were identified. Novel and published rbcL mini-barcode primers were evaluated for PCR amplification [determined with a validated electronic simulation (n = 2765) and empirically (n = 188)], Sanger sequence quality [determined empirically (n = 188)], and taxonomic discrimination [determined empirically (n = 30,472)]. PCR amplification for all mini-barcodes, as estimated by validated electronic simulation, was successful for 90.2-99.8% of species. Overall Sanger sequence quality for mini-barcodes was very low - the best mini-barcode tested produced sequences of adequate quality (B20 ≥ 0.5) for 74.5% of samples. The majority of mini-barcodes provide correct identifications of families in excess of 70.1% of the time. Discriminatory power noticeably decreased at lower taxonomic levels. At the species level, the discriminatory power of the best mini-barcode was less than 38.2%. For samples believed to contain DNA from only one species, an investigator should attempt to sequence, in decreasing order of utility and probability of success, mini-barcodes F (rbcL1/rbcLB), D (F52/R193) and K (F517/R604). For samples believed to contain DNA from more than one species, an investigator should amplify and sequence mini-barcode D (F52/R193). © 2013 John Wiley & Sons Ltd.

Mini-Rocket User Guide

DTIC Science & Technology

2007-08-01

26 ISTC Simulation Comparisons ............................................................................... 29 STARS...Range Comparison Figure 8. ISTC Simulntioiz Comparisons 29 Mini-Rocket User Guide REAL-WORLD COMPARISON In particular, note the very high angle-of...not directly model the missile rigid body dynamics. The ISTC subsequently used Mini-Rocket as a driver to stimulate other models and as a risk

NEW CLASS OF VERY HIGH ENERGY {gamma}-RAY EMITTERS: RADIO-DARK MINI SHELLS SURROUNDING ACTIVE GALACTIC NUCLEUS JETS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kino, Motoki; Ito, Hirotaka; Kawakatu, Nozomu

We explore non-thermal emission from a shocked interstellar medium, which is identified as an expanding shell, driven by a relativistic jet in active galactic nuclei (AGNs). In this work, we particularly focus on parsec-scale size mini shells surrounding mini radio lobes. From the radio to X-ray band, the mini radio lobe emission dominates the faint emission from the mini shell. On the other hand, we find that inverse-Compton (IC) emission from the shell can overwhelm the associated lobe emission at the very high energy (VHE; E > 100 GeV) {gamma}-ray range, because energy densities of synchrotron photons from the lobemore » and/or soft photons from the AGN nucleus are large and IC scattering works effectively. The predicted IC emission from nearby mini shells can be detected with the Cherenkov Telescope Array and they are potentially a new class of VHE {gamma}-ray emitters.« less

Mini-rack testbed evaluation

NASA Technical Reports Server (NTRS)

Gosbee, John; Stegmann, Barbara; Guess, Terrell M.

1991-01-01

The goal was to characterize the Health Maintenance Facility (HMF)-like mini-racks and drawers onboard the KC-135 as a test bed for the Space Station Freedom HMF racks. An additional goal was to evaluate the attachments, mounting points, and inner drawer assemblies of the mini-racks for various medical equipment and supplies. Results and recommendations are given.

The MiniBooNE detector

NASA Astrophysics Data System (ADS)

Aguilar-Arevalo, A. A.; Anderson, C. E.; Bartoszek, L. M.; Bazarko, A. O.; Brice, S. J.; Brown, B. C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J. M.; Cox, D. C.; Curioni, A.; Djurcic, Z.; Finley, D. A.; Fleming, B. T.; Ford, R.; Garcia, F. G.; Garvey, G. T.; Green, C.; Green, J. A.; Hart, T. L.; Hawker, E.; Imlay, R.; Johnson, R. A.; Karagiorgi, G.; Kasper, P.; Katori, T.; Kobilarcik, T.; Kourbanis, I.; Koutsoliotas, S.; Laird, E. M.; Linden, S. K.; Link, J. M.; Liu, Y.; Liu, Y.; Louis, W. C.; Mahn, K. B. M.; Marsh, W.; Martin, P. S.; McGregor, G.; Metcalf, W.; Meyer, H.-O.; Meyers, P. D.; Mills, F.; Mills, G. B.; Monroe, J.; Moore, C. D.; Nelson, R. H.; Nguyen, V. T.; Nienaber, P.; Nowak, J. A.; Ouedraogo, S.; Patterson, R. B.; Perevalov, D.; Polly, C. C.; Prebys, E.; Raaf, J. L.; Ray, H.; Roe, B. P.; Russell, A. D.; Sandberg, V.; Sands, W.; Schirato, R.; Schofield, G.; Schmitz, D.; Shaevitz, M. H.; Shoemaker, F. C.; Smith, D.; Soderberg, M.; Sorel, M.; Spentzouris, P.; Stancu, I.; Stefanski, R. J.; Sung, M.; Tanaka, H. A.; Tayloe, R.; Tzanov, M.; Van de Water, R.; Wascko, M. O.; White, D. H.; Wilking, M. J.; Yang, H. J.; Zeller, G. P.; Zimmerman, E. D.; MiniBooNE Collaboration

2009-02-01

The MiniBooNE neutrino detector was designed and built to look for ν→ν oscillations in the (sin 2θ,Δm) parameter space region where the LSND experiment reported a signal. The MiniBooNE experiment used a beam energy and baseline that were an order of magnitude larger than those of LSND so that the backgrounds and systematic errors would be completely different. This paper provides a detailed description of the design, function, and performance of the MiniBooNE detector.

Introducing a Low-Cost Mini-Uav for - and Multispectral-Imaging

NASA Astrophysics Data System (ADS)

Bendig, J.; Bolten, A.; Bareth, G.

2012-07-01

, and is capturing the temperature range between -20 °C and 100 °C. Flying at a height of 100 m, the camera's image covers an area of approx. 50 by 40 m. The sensor's resolution is 160 x 120 pixel and the field of view is 28° (H) x 21° (V). According to the producer, absolute accuracy for temperature is ±1 °C and the thermal sensitivity is >0.1 K. Additionally, the MK-Okto is equipped with Tetracam's Mini MCA. The Mini MCA in our study is a four band multispectral imaging system. Total weight is 700 g and spectral characteristics can be modified by filters between 400 and 1000 nm. In this study, three bands with a width of 10 nm (green: 550 nm, red: 671 nm, NIR1: 800 nm) and one band of 20 nm width (NIR2: 950 nm) have been used. Even so the MK-Okto is able to carry both sensors at the same time, the imaging systems were used separately for this contribution. First results of a combined thermal- and multispectral MK-Okto campaign in 2011 are presented and evaluated for a sugarbeet field experiment examining pathogens and drought stress.

Fracture strength of orthodontic mini-implants

PubMed Central

Assad-Loss, Tatiana Feres; Kitahara-Céia, Flávia Mitiko Fernandes; Silveira, Giordani Santos; Elias, Carlos Nelson; Mucha, José Nelson

2017-01-01

ABSTRACT Objective: This study aimed at evaluating the design and dimensions of five different brands of orthodontic mini-implants, as well as their influence on torsional fracture strength. Methods: Fifty mini-implants were divided into five groups corresponding to different manufactures (DEN, RMO, CON, NEO, SIN). Twenty-five mini-implants were subjected to fracture test by torsion in the neck and the tip, through arbors attached to a Universal Mechanical Testing Machine. The other 25 mini-implants were subjected to insertion torque test into blocks of pork ribs using a torquimeter and contra-angle handpiece mounted in a surgical motor. The shape of the active tip of the mini-implants was evaluated under microscopy. The non-parametric Friedman test and Snedecor’s F in analysis of variance (ANOVA) were used to evaluate the differences between groups. Results: The fracture torque of the neck ranged from 23.45 N.cm (DEN) to 34.82 N.cm (SIN), and of the tip ranged from 9.35 N.cm (CON) to 24.36 N.cm (NEO). Insertion torque values ranged from 6.6 N.cm (RMO) to 10.2 N.cm (NEO). The characteristics that most influenced the results were outer diameter, inner diameter, the ratio between internal and external diameters, and the existence of milling in the apical region of the mini-implant. Conclusions: The fracture torques were different for both the neck and the tip of the five types evaluated. NEO and SIN mini-implants showed the highest resistance to fracture of the neck and tip. The fracture torques of both tip and neck were higher than the torque required to insert mini-implants. PMID:28746487

Are Ducted Mini-Splits Worth It?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winkler, Jonathan M; Maguire, Jeffrey B; Metzger, Cheryn E.

Ducted mini-split heat pumps are gaining popularity in some regions of the country due to their energy-efficient specifications and their ability to be hidden from sight. Although product and install costs are typically higher than the ductless mini-split heat pumps, this technology is well worth the premium for some homeowners who do not like to see an indoor unit in their living area. Due to the interest in this technology by local utilities and homeowners, the Bonneville Power Administration (BPA) has funded the Pacific Northwest National Laboratory (PNNL) and the National Renewable Energy Laboratory (NREL) to develop capabilities within themore » Building Energy Optimization (BEopt) tool to model ducted mini-split heat pumps. After the fundamental capabilities were added, energy-use results could be compared to other technologies that were already in BEopt, such as zonal electric resistance heat, central air source heat pumps, and ductless mini-split heat pumps. Each of these technologies was then compared using five prototype configurations in three different BPA heating zones to determine how the ducted mini-split technology would perform under different scenarios. The result of this project was a set of EnergyPlus models representing the various prototype configurations in each climate zone. Overall, the ducted mini-split heat pumps saved about 33-60% compared to zonal electric resistance heat (with window AC systems modeled in the summer). The results also showed that the ducted mini-split systems used about 4% more energy than the ductless mini-split systems, which saved about 37-64% compared to electric zonal heat (depending on the prototype and climate).« less

Genetically targeted 3D visualisation of Drosophila neurons under Electron Microscopy and X-Ray Microscopy using miniSOG

PubMed Central

Ng, Julian; Browning, Alyssa; Lechner, Lorenz; Terada, Masako; Howard, Gillian; Jefferis, Gregory S. X. E.

2016-01-01

Large dimension, high-resolution imaging is important for neural circuit visualisation as neurons have both long- and short-range patterns: from axons and dendrites to the numerous synapses at terminal endings. Electron Microscopy (EM) is the favoured approach for synaptic resolution imaging but how such structures can be segmented from high-density images within large volume datasets remains challenging. Fluorescent probes are widely used to localise synapses, identify cell-types and in tracing studies. The equivalent EM approach would benefit visualising such labelled structures from within sub-cellular, cellular, tissue and neuroanatomical contexts. Here we developed genetically-encoded, electron-dense markers using miniSOG. We demonstrate their ability in 1) labelling cellular sub-compartments of genetically-targeted neurons, 2) generating contrast under different EM modalities, and 3) segmenting labelled structures from EM volumes using computer-assisted strategies. We also tested non-destructive X-ray imaging on whole Drosophila brains to evaluate contrast staining. This enabled us to target specific regions for EM volume acquisition. PMID:27958322

Diagnostic validity Polish language version of the questionnaire MINI-KID (Mini International Neuropsychiatry Interview for Children and Adolescent).

PubMed

Adamowska, Sylwia; Sylwia, Adamowska; Adamowski, Tomasz; Tomasz, Adamowski; Frydecka, Dorota; Dorota, Frydecka; Kiejna, Andrzej; Andrzej, Kiejna

2014-10-01

Since over forty years structuralized interviews for clinical and epidemiological research in child and adolescent psychiatry are being developed that should increase validity and reliability of diagnoses according to classification systems (DSM and ICD). The aim of the study is to assess the validity of the Polish version of MINI-KID (Mini International Neuropsychiatric Interview for Children and Adolescents) in comparison to clinical diagnosis made by a specialist in the field of child and adolescent psychiatry. There were 140 patients included in the study (93 boys, 66.4%, mean age 11.8±3.0 and 47 girls 33.5%, mean age 14.0±2.9). All the patients were diagnosed by the specialist in the field of child and adolescent psychiatry according to ICD-10 criteria and by the independent interviewer with the Polish version of MINI-KID (version 2.0, 2001). There was higher agreement between clinical diagnoses and diagnoses based on MINI-KID interview with respect to eating disorders and externalizing disorders (κ 0.43-0.56) and lower in internalizing disorders (κ 0.13-0.45). In the clinical interview, there was smaller number of diagnostic categories (maximum 3 diagnoses per one patient) in comparison to MINI-KID (maximum 10 diagnoses per one patient), and the smaller percentage of patients with one diagnosis (65,7%) in comparison to MINI-KID interview (72%). Our study has shown satisfactory validity parameters of MINI-KID questionnaire, promoting its use for clinical and epidemiological settings. The Mini International Neuropsychiatry Interview for Children and Adolescent (MINI-KID) is the first structuralized diagnostic interview for assessing mental status in children and adolescents, which has been translated into Polish language. Our validation study demonstrated satisfactory psychometric properties of the questionnaire, enabling its use in clinical practice and in research projects. Copyright © 2014 Elsevier Inc. All rights reserved.

Mini-Sniffer on Lakebed

NASA Technical Reports Server (NTRS)

1974-01-01

The original Mini-Sniffer on Rogers Dry Lake, adjacent to NASA's Flight Research Center, Edwards AFB. This version of the remotely-piloted vehicle had swept-back wings, tip rudders, nose canards, and an air breathing engine. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the planet Mars, where the gravity (38 percent of that on Earth) would reduce the horsepower needed for flight.

Comparison Between Transverse Mini-Incision and Longitudinal Mini-Incision for the Resection of Locally Advanced Colonic Cancer

PubMed Central

Ishida, Hideyuki; Sobajima, Jun; Yokoyama, Masaru; Nakada, Hiroshi; Okada, Norimichi; Kumamoto, Kensuke; Ishibashi, Keiichiro

2014-01-01

We performed a retrospective review of non-overweight (body mass index ≤ 25 kg/m2) patients scheduled to undergo a curative resection of locally advanced colon cancer via a transverse mini-incision (n = 62) or a longitudinal mini-incision (skin incision ≤7 cm, n = 62), with the latter group of patients randomly selected as historical controls matched with the former group according to tumor location. Extension of the transverse mini-incision wound was necessary in 3 patients (5%). Both groups were largely equivalent in terms of demographic, clinicopathological, and surgical factors and frequency of postoperative complications. Postoperative analgesic was significantly less (P = 0.04) and postoperative length of the hospital stay was significantly shorter (P < 0.01) in the transverse mini-incision group. Concerning a mini-incision approach for locally advanced colonic cancer, a transverse incision seems to be advantageous with regard to minimal invasiveness and early recovery compared with a longitudinal incision. PMID:24833142

Mini-Sniffer II in Flight

NASA Technical Reports Server (NTRS)

1976-01-01

This photograph shows the second Mini-Sniffer undergoing flight testing over Rogers Dry Lake in Edwards, California. This version of the Mini-Sniffer lacked the canard of the original version and had wing tips and tail booms added. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the planet Mars, where the gravity (38 percent of that on Earth) would reduce the horsepower needed for flight.

A CHANDRA-VLA INVESTIGATION OF THE X-RAY CAVITY SYSTEM AND RADIO MINI-HALO IN THE GALAXY CLUSTER RBS 797

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doria, Alberto; Gitti, Myriam; Brighenti, Fabrizio

2012-07-01

We present a study of the cavity system in the galaxy cluster RBS 797 based on Chandra and Very Large Array (VLA) data. RBS 797 (z = 0.35) is one of the most distant galaxy clusters in which two pronounced X-ray cavities have been discovered. The Chandra data confirm the presence of a cool core and indicate a higher metallicity along the cavity directions. This is likely due to the active galactic nucleus outburst, which lifts cool metal-rich gas from the center along the cavities, as seen in other systems. We find indications that the cavities are hotter than themore » surrounding gas. Moreover, the new Chandra images show bright rims contrasting with the deep, X-ray deficient cavities. The likely cause is that the expanding 1.4 GHz radio lobes have displaced the gas, compressing it into a shell that appears as bright cool arms. Finally, we show that the large-scale radio emission detected with our VLA observations may be classified as a radio mini-halo, powered by the cooling flow, as it nicely follows the trend P{sub radio} versus P{sub CF} predicted by the reacceleration model.« less

MINIS: Multipurpose Interactive NASA Information System

NASA Technical Reports Server (NTRS)

1976-01-01

The Multipurpose Interactive NASA Information Systems (MINIS) was developed in response to the need for a data management system capable of operation on several different minicomputer systems. The desired system had to be capable of performing the functions of a LANDSAT photo descriptive data retrieval system while remaining general in terms of other acceptable user definable data bases. The system also had to be capable of performing data base updates and providing user-formatted output reports. The resultant MINI System provides all of these capabilities and several other features to complement the data management system. The MINI System is currently implemented on two minicomputer systems and is in the process of being installed on another minicomputer system. The MINIS is operational on four different data bases.

Psychometric Properties of the Mini-Social Phobia Inventory

PubMed Central

Seeley-Wait, Elizabeth; Rapee, Ronald M.

2009-01-01

Objective: Although a potentially useful measure, to date, there has been only one published test of the psychometric properties of the Mini-Social Phobia Inventory (Mini-SPIN). Therefore, the psychometric properties of the Mini-SPIN, a brief 3-item screen for social anxiety disorder, were examined. Method: Participants were 186 patients diagnosed with social anxiety disorder (DSM-IV criteria) attending a specialized anxiety disorders clinic for treatment, and 56 nonclinical participants were recruited to serve as comparisons. Participants were diagnosed using the Anxiety Disorders Interview Schedule for DSM-IV, and they also completed the Mini-SPIN, the Social Interaction Anxiety Scale (SIAS), and the Social Phobia Scale (SPS). Construct validity for the Mini-SPIN was assessed by its correlations with the SIAS and the SPS. Reliability, internal consistency, discriminant validity, and sensitivity to change were also examined, and receiver operating characteristic curve analysis was conducted to determine guidelines regarding cutoff scores for the Mini-SPIN. The study was conducted between April 1999 and December 2001. Results: Supporting findings from a previous study, strong support was found for the Mini-SPIN's ability to discriminate individuals with social anxiety disorder from those without the disorder. Receiver operating characteristic analysis revealed that using a cutoff score of 6 or greater (P < .001), the Mini-SPIN demonstrates excellent sensitivity, specificity, and positive and negative predictive values. Conclusions: Findings suggest that the Mini-SPIN is a reliable and valid instrument for screening social anxiety disorder in adults. Importantly, the use of the Mini-SPIN in primary care may be one way to address the underrecognition of social anxiety disorder in such settings. Due to the ease and brevity of the measure, it also shows potential for use in epidemiology. Given that this study has revealed the ability of the Mini-SPIN to reflect

Quality Assurance Framework for Mini-Grids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Esterly, Sean; Baring-Gould, Ian; Booth, Samuel

To address the root challenges of providing quality power to remote consumers through financially viable mini-grids, the Global Lighting and Energy Access Partnership (Global LEAP) initiative of the Clean Energy Ministerial and the U.S. Department of Energy teamed with the National Renewable Energy Laboratory (NREL) and Power Africa to develop a Quality Assurance Framework (QAF) for isolated mini-grids. The framework addresses both alternating current (AC) and direct current (DC) mini-grids, and is applicable to renewable, fossil-fuel, and hybrid systems.

Quality Assurance Framework for Mini-Grids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baring-Gould, Ian; Burman, Kari; Singh, Mohit

Providing clean and affordable energy services to the more than 1 billion people globally who lack access to electricity is a critical driver for poverty reduction, economic development, improved health, and social outcomes. More than 84% of populations without electricity are located in rural areas where traditional grid extension may not be cost-effective; therefore, distributed energy solutions such as mini-grids are critical. To address some of the root challenges of providing safe, quality, and financially viable mini-grid power systems to remote customers, the U.S. Department of Energy (DOE) teamed with the National Renewable Energy Laboratory (NREL) to develop a Qualitymore » Assurance Framework (QAF) for isolated mini-grids. The QAF for mini-grids aims to address some root challenges of providing safe, quality, and affordable power to remote customers via financially viable mini-grids through two key components: (1) Levels of service: Defines a standard set of tiers of end-user service and links them to technical parameters of power quality, power availability, and power reliability. These levels of service span the entire energy ladder, from basic energy service to high-quality, high-reliability, and high-availability service (often considered 'grid parity'); (2) Accountability and performance reporting framework: Provides a clear process of validating power delivery by providing trusted information to customers, funders, and/or regulators. The performance reporting protocol can also serve as a robust monitoring and evaluation tool for mini-grid operators and funding organizations. The QAF will provide a flexible alternative to rigid top-down standards for mini-grids in energy access contexts, outlining tiers of end-user service and linking them to relevant technical parameters. In addition, data generated through implementation of the QAF will provide the foundation for comparisons across projects, assessment of impacts, and greater confidence that will

The Psychometrics of the Mini-K.

PubMed

Richardson, George B; Chen, Ching-Chen; Dai, Chia-Liang; Brubaker, Michael D; Nedelec, Joseph L

2017-01-01

Many published studies have employed the Mini-K to measure a single fast-slow life history dimension. However, the internal structure of the Mini-K has not been determined and it is not clear that a single higher order K-factor fits the data. It is also not clear that the Mini-K is measurement invariant across groups such as the sexes. To establish the construct validity of K as well as the broader usefulness of applying life history theory to humans, it is crucial that these psychometric issues are addressed as a part of measure validation efforts. Here we report on three studies that used latent variable modeling and data drawn from two college student samples ( ns = 361 and 300) to elucidate the psychometrics of the Mini-K. We found that (a) the Mini-K had a six dimensional first-order structure, (b) the K-factor provided a parsimonious explanation of the associations among the lower order factors at no significant cost to fit, (c) the Mini-K measured the same K-factor across the sexes, (d) K-factor means did not have the same meaning across the sexes and thus the first-order factors should be used in studies of mean sex differences, and finally, (e) the K-factor was only associated with environment and aspects of mating competition in females. Implications and future directions for life history research are discussed.

Mini-Membrane Evaporator for Contingency Spacesuit Cooling

NASA Technical Reports Server (NTRS)

Makinen, Janice V.; Bue, Grant C.; Campbell, Colin; Petty, Brian; Craft, Jesse; Lynch, William; Wilkes, Robert; Vogel, Matthew

2015-01-01

The next-generation Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System (PLSS) is integrating a number of new technologies to improve reliability and functionality. One of these improvements is the development of the Auxiliary Cooling Loop (ACL) for contingency crewmember cooling. The ACL is a completely redundant, independent cooling system that consists of a small evaporative cooler--the Mini Membrane Evaporator (Mini-ME), independent pump, independent feedwater assembly and independent Liquid Cooling Garment (LCG). The Mini-ME utilizes the same hollow fiber technology featured in the full-sized AEMU PLSS cooling device, the Spacesuit Water Membrane Evaporator (SWME), but Mini-ME occupies only approximately 25% of the volume of SWME, thereby providing only the necessary crewmember cooling in a contingency situation. The ACL provides a number of benefits when compared with the current EMU PLSS contingency cooling technology, which relies upon a Secondary Oxygen Vessel; contingency crewmember cooling can be provided for a longer period of time, more contingency situations can be accounted for, no reliance on a Secondary Oxygen Vessel (SOV) for contingency cooling--thereby allowing a reduction in SOV size and pressure, and the ACL can be recharged-allowing the AEMU PLSS to be reused, even after a contingency event. The first iteration of Mini-ME was developed and tested in-house. Mini-ME is currently packaged in AEMU PLSS 2.0, where it is being tested in environments and situations that are representative of potential future Extravehicular Activities (EVA's). The second iteration of Mini-ME, known as Mini-ME2, is currently being developed to offer more heat rejection capability. The development of this contingency evaporative cooling system will contribute to a more robust and comprehensive AEMU PLSS.

Mini-Membrane Evaporator for Contingency Spacesuit Cooling

NASA Technical Reports Server (NTRS)

Makinen, Janice V.; Bue, Grant C.; Campbell, Colin; Craft, Jesse; Lynch, William; Wilkes, Robert; Vogel, Matthew

2014-01-01

The next-generation Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System (PLSS) is integrating a number of new technologies to improve reliability and functionality. One of these improvements is the development of the Auxiliary Cooling Loop (ACL) for contingency crewmember cooling. The ACL is a completely redundant, independent cooling system that consists of a small evaporative cooler--the Mini Membrane Evaporator (Mini-ME), independent pump, independent feedwater assembly and independent Liquid Cooling Garment (LCG). The Mini-ME utilizes the same hollow fiber technology featured in the full-sized AEMU PLSS cooling device, the Spacesuit Water Membrane Evaporator (SWME), but Mini-ME occupies only 25% of the volume of SWME, thereby providing only the necessary crewmember cooling in a contingency situation. The ACL provides a number of benefits when compared with the current EMU PLSS contingency cooling technology, which relies upon a Secondary Oxygen Vessel; contingency crewmember cooling can be provided for a longer period of time, more contingency situations can be accounted for, no reliance on a Secondary Oxygen Vessel (SOV) for contingency cooling--thereby allowing a reduction in SOV size and pressure, and the ACL can be recharged-allowing the AEMU PLSS to be reused, even after a contingency event. The first iteration of Mini-ME was developed and tested in-house. Mini-ME is currently packaged in AEMU PLSS 2.0, where it is being tested in environments and situations that are representative of potential future Extravehicular Activities (EVA's). The second iteration of Mini-ME, known as Mini- ME2, is currently being developed to offer more heat rejection capability. The development of this contingency evaporative cooling system will contribute to a more robust and comprehensive AEMU PLSS.

Spurious RF signals emitted by mini-UAVs

NASA Astrophysics Data System (ADS)

Schleijpen, Ric (H. M. A.); Voogt, Vincent; Zwamborn, Peter; van den Oever, Jaap

2016-10-01

This paper presents experimental work on the detection of spurious RF emissions of mini Unmanned Aerial Vehicles (mini-UAV). Many recent events have shown that mini-UAVs can be considered as a potential threat for civil security. For this reason the detection of mini-UAVs has become of interest to the sensor community. The detection, classification and identification chain can take advantage of different sensor technologies. Apart from the signatures used by radar and electro-optical sensor systems, the UAV also emits RF signals. These RF signatures can be split in intentional signals for communication with the operator and un-intentional RF signals emitted by the UAV. These unintentional or spurious RF emissions are very weak but could be used to discriminate potential UAV detections from false alarms. The goal of this research was to assess the potential of exploiting spurious emissions in the classification and identification chain of mini-UAVs. It was already known that spurious signals are very weak, but the focus was on the question whether the emission pattern could be correlated to the behaviour of the UAV. In this paper experimental examples of spurious RF emission for different types of mini-UAVs and their correlation with the electronic circuits in the UAVs will be shown

Nanostructured severe plastic deformation processed titanium for orthodontic mini-implants.

PubMed

Serra, Glaucio; Morais, Liliane; Elias, Carlos Nelson; Semenova, Irina P; Valiev, Ruslan; Salimgareeva, Gulnaz; Pithon, Matheus; Lacerda, Rogério

2013-10-01

Titanium mini-implants have been successfully used as anchorage devices in Orthodontics. Commercially pure titanium (cpTi) was recently replaced by Ti-6Al-4V alloy as the mini-implant material base due to the higher strength properties of the alloy. However, the lower corrosion resistance and the lower biocompatibility have been lowering the success rate of Ti-6Al-4V mini-implants. Nanostructured titanium (nTi) is commercially pure titanium that was nanostructured by a specific technique of severe plastic deformation. It is bioinert, does not contain potentially toxic or allergic additives, and has higher specific strength properties than any other titanium applied in medical implants. The higher strength properties associated to the higher biocompatibility make nTi potentially useful for orthodontic mini-implant applications, theoretically overcoming cpTi and Ti-6Al-4V mini-implants. The purposes of the this work were to process nTi, to mechanically compare cpTi, Ti-6Al-4V, and nTi mini-implants by torque test, and to evaluate both the surface morphology and the fracture surface characteristics of them by SEM. Torque test results showed significant increase in the maximum torque resistance of nTi mini-implants when compared to cpTi mini-implants, and no statistical difference between Ti-6Al-4V and nTi mini-implants. SEM analysis demonstrated smooth surface morphology and transgranular fracture aspect for nTi mini-implants. Since nanostructured titanium mini-implants have mechanical properties comparable to titanium alloy mini-implants, and biocompatibility comparable to commercially pure titanium mini-implants, it is suggestive that nanostructured titanium can replace Ti-6Al-4V alloy as the material base for mini-implants. Copyright © 2013 Elsevier B.V. All rights reserved.

Mini-Sniffer III on Lakebed

NASA Technical Reports Server (NTRS)

1976-01-01

The third remotely-piloted Mini-Sniffer research vehicle rests on the lakebed adjacent to the Dryden Flight Research Center, Edwards, California. This view shows the wing shape, hydrazine engine, and the tail booms. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the planet Mars, where the gravity (38 percent of that on Earth) would reduce the horsepower needed for flight.

[Application of distal palm perforator mini-flap in repair of scar contracture of digital web-spaces].

PubMed

Zhou, Xiao; Xu, Yajun; Rui, Yongjun; Shou, Kuishui; Yao, Qun

2011-02-01

To discuss the effectiveness of distal palm perforator mini-flap in the treatment of scar contracture of digital web-spaces. Between August 2008 and March 2010, 6 cases of scar contracture of digital web-spaces were treated, including 4 males and 2 females and aging 16-68 years (mean, 45 years). The causes were burn injury, twisting injury, and crush injury in 2 cases, respectively. The disease duration was from 3 months to 3 years. The affected digital web-spaces were from index finger to middle finger in 2 cases, from middle finger to ring finger in 3 cases, and from ring finger to small finger in 1 case. The maximum abduction degree of digital web-spaces was 5-10 degrees. The sizes and the depths of reshape of digital web-spaces disappeared. The defect size ranged from 20 mm x 8 mm to 30 mm x 13 mm after opening digital web-spaces. The size of the distal palm perforator mini-flap ranged from 25 mm x 10 mm to 35 mm x 15 mm. The donor sites were sutured directly. All 6 flaps survived and got primary healing. Incisions at donor sites healed by first intention. All patients were followed up 6-12 months. The reconstructed digital web-spaces had good appearance and soft texture. The range of motion of metacarpophalangeal joint was normal. The sizes and the depths of reshape of digital web-spaces were similar to normal ones. The maximum abduction degree of digital web-spaces was 40-60 degrees. There was no scar contracture of incision of palm. The shape of flaps and function of the fingers were satisfactory after 6-12 months of follow-up. It is an ideal method to treat scar contracture of digital web-spaces with distal palm perforator mini-flap.

Mini-marathon groups: psychological "first aid" following disasters.

PubMed

Terr, L C

1992-01-01

Large group counseling sessions for soldiers following battle have been commonly used since World War II. The author conceptualizes and demonstrates how these mini-marathon sessions can be adapted to support all ages and types of civilians involved in disasters. Mini-marathons take about 3 hours and are divided into three sections: story sharing, symptom sharing, and suggestions for self-help, including sharing tales of heroism and survival. After an initial mini-marathon session, a second session may be held emphasizing creativity. The author also describes how mini-marathons can be adapted for therapists who will lead their own sessions.

Teaching Economics in the Mini-Economy.

ERIC Educational Resources Information Center

Indiana State Dept. of Education, Indianapolis.

This booklet produced by the State of Indiana introduces elementary teachers to economic concepts appropriate to the elementary curriculum and explains how to use mini-economy activities to teach these concepts. Chapter 1 describes how the mini-economy works, while chapter 2 introduces basic economic vocabulary and discusses market economy. Ideas…

Evaluation of fracture torque resistance of orthodontic mini-implants.

PubMed

Dalla Rosa, Fernando; Burmann, Paola Fp; Ruschel, Henrique C; Vargas, Ivana A; Kramer, Paulo F

2016-12-01

This study sought to assess the fracture torque resistance of mini-implants used for orthodontic anchorage. Five commercially available brands of mini-implants were used (SIN®, CONEXÃO®, NEODENT®, MORELLI®, andFORESTADENT®). Ten mini-implants of each diameter of each brand were tested, for a total 100 specimens. The mini-implants were subject to a static torsion test as described in ASTMstandard F543. Analysis of variance (ANOVA) with the Tukey multiple comparisons procedure was used to assess results. Overall, mean fracture strength ranged from 15.7 to 70.4 N·cm. Mini-implants with larger diameter exhibited higher peak torque values at fracture and higher yield strength, regardless of brand. In addition, significant differences across brands were observed when implants were stratified by diameter. In conclusion, larger mini-implant diameter is associated with increased fracture torque resistance. Additional information on peak torque values at fracture of different commercial brands of mini-implants may increase the success rate of this orthodontic anchorage modality. Sociedad Argentina de Investigación Odontológica.

The use of mini-samples in palaeomagnetism

NASA Astrophysics Data System (ADS)

Böhnel, Harald; Michalk, Daniel; Nowaczyk, Norbert; Naranjo, Gildardo Gonzalez

2009-10-01

Rock cores of ~25 mm diameter are widely used in palaeomagnetism. Occasionally smaller diameters have been used as well which represents distinct advantages in terms of throughput, weight of equipment and core collections. How their orientation precision compares to 25 mm cores, however, has not been evaluated in detail before. Here we compare the site mean directions and their statistical parameters for 12 lava flows sampled with 25 mm cores (standard samples, typically 8 cores per site) and with 12 mm drill cores (mini-samples, typically 14 cores per site). The site-mean directions for both sample sizes appear to be indistinguishable in most cases. For the mini-samples, site dispersion parameters k on average are slightly lower than for the standard samples reflecting their larger orienting and measurement errors. Applying the Wilcoxon signed-rank test the probability that k or α95 have the same distribution for both sizes is acceptable only at the 17.4 or 66.3 per cent level, respectively. The larger mini-core numbers per site appears to outweigh the lower k values yielding also slightly smaller confidence limits α95. Further, both k and α95 are less variable for mini-samples than for standard size samples. This is interpreted also to result from the larger number of mini-samples per site, which better averages out the detrimental effect of undetected abnormal remanence directions. Sampling of volcanic rocks with mini-samples therefore does not present a disadvantage in terms of the overall obtainable uncertainty of site mean directions. Apart from this, mini-samples do present clear advantages during the field work, as about twice the number of drill cores can be recovered compared to 25 mm cores, and the sampled rock unit is then more widely covered, which reduces the contribution of natural random errors produced, for example, by fractures, cooling joints, and palaeofield inhomogeneities. Mini-samples may be processed faster in the laboratory, which is of

Habitable evaporated cores: transforming mini-Neptunes into super-Earths in the habitable zones of M dwarfs.

PubMed

Luger, R; Barnes, R; Lopez, E; Fortney, J; Jackson, B; Meadows, V

2015-01-01

We show that photoevaporation of small gaseous exoplanets ("mini-Neptunes") in the habitable zones of M dwarfs can remove several Earth masses of hydrogen and helium from these planets and transform them into potentially habitable worlds. We couple X-ray/extreme ultraviolet (XUV)-driven escape, thermal evolution, tidal evolution, and orbital migration to explore the types of systems that may harbor such "habitable evaporated cores" (HECs). We find that HECs are most likely to form from planets with ∼1 M⊕ solid cores with up to about 50% H/He by mass, though whether or not a given mini-Neptune forms a HEC is highly dependent on the early XUV evolution of the host star. As terrestrial planet formation around M dwarfs by accumulation of local material is likely to form planets that are small and dry, evaporation of small migrating mini-Neptunes could be one of the dominant formation mechanisms for volatile-rich Earths around these stars.

Failure rates of mini-implants placed in the infrazygomatic region.

PubMed

Uribe, Flavio; Mehr, Rana; Mathur, Ajay; Janakiraman, Nandakumar; Allareddy, Veerasathpurush

2015-01-01

The purpose of this pilot study was to evaluate the failure rates of mini-implants placed in the infrazygomatic region and to evaluate factors that affect their stability. A retrospective cohort study of 30 consecutive patients (55 mini-implants) who had infrazygomatic mini-implants at a University Clinic were evaluated for failure rates. Patient, mini-implant, orthodontic, surgical, and mini-implant maintenance factors were evaluated by univariate logistic regression models for association to failure rates. A 21.8 % failure rate of mini-implants placed in the infazygomatic region was observed. None of the predictor variables were significantly associated with higher or lower odds for failed implants. Failure rates for infrazygomatic mini-implants were slightly higher than those reported in other maxilla-mandibular osseous locations. No predictor variables were found to be associated to the failure rates.

A Measurement of the muon neutrino charged current quasielastic interaction and a test of Lorentz violation with the MiniBooNE experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Katori, Teppei

2008-12-01

The Mini-Booster neutrino experiment (MiniBooNE) at Fermi National Accelerator Laboratory (Fermilab) is designed to search for v μ → v e appearance neutrino oscillations. Muon neutrino charged-current quasi-elastic (CCQE) interactions (v μ + n → μ + p) make up roughly 40% of our data sample, and it is used to constrain the background and cross sections for the oscillation analysis. Using high-statistics MiniBooNE CCQE data, the muon-neutrino CCQE cross section is measured. The nuclear model is tuned precisely using the MiniBooNE data. The measured total cross section is σ = (1.058 ± 0.003 (stat) ± 0.111 (syst)) x 10more » -38 cm 2 at the MiniBooNE muon neutrino beam energy (700-800 MeV). v e appearance candidate data is also used to search for Lorentz violation. Lorentz symmetry is one of the most fundamental symmetries in modern physics. Neutrino oscillations offer a new method to test it. We found that the MiniBooNE result is not well-described using Lorentz violation, however further investigation is required for a more conclusive result.« less

Conducting Slug Tests in Mini-Piezometers.

PubMed

Fritz, Bradley G; Mackley, Rob D; Arntzen, Evan V

2016-03-01

Slug tests performed using mini-piezometers with internal diameters as small as 0.43 cm can provide a cost effective tool for hydraulic characterization. We evaluated the hydraulic properties of the apparatus in a laboratory environment and compared those results with field tests of mini-piezometers installed into locations with varying hydraulic properties. Based on our evaluation, slug tests conducted in mini-piezometers using the fabrication and installation approach described here are effective within formations where the hydraulic conductivity is less than 1 × 10(-3) cm/s. While these constraints limit the potential application of this method, the benefits to this approach are that the installation, measurement, and analysis is cost effective, and the installation can be completed in areas where other (larger diameter) methods might not be possible. Additionally, this methodology could be applied to existing mini-piezometers previously installed for other purposes. Such analysis of existing installations could be beneficial in interpreting previously collected data (e.g., water-quality data or hydraulic head data). © 2015, National Ground Water Association.

rAAV-compatible MiniPromoters for restricted expression in the brain and eye.

PubMed

de Leeuw, Charles N; Korecki, Andrea J; Berry, Garrett E; Hickmott, Jack W; Lam, Siu Ling; Lengyell, Tess C; Bonaguro, Russell J; Borretta, Lisa J; Chopra, Vikramjit; Chou, Alice Y; D'Souza, Cletus A; Kaspieva, Olga; Laprise, Stéphanie; McInerny, Simone C; Portales-Casamar, Elodie; Swanson-Newman, Magdalena I; Wong, Kaelan; Yang, George S; Zhou, Michelle; Jones, Steven J M; Holt, Robert A; Asokan, Aravind; Goldowitz, Daniel; Wasserman, Wyeth W; Simpson, Elizabeth M

2016-05-10

Small promoters that recapitulate endogenous gene expression patterns are important for basic, preclinical, and now clinical research. Recently, there has been a promising revival of gene therapy for diseases with unmet therapeutic needs. To date, most gene therapies have used viral-based ubiquitous promoters-however, promoters that restrict expression to target cells will minimize off-target side effects, broaden the palette of deliverable therapeutics, and thereby improve safety and efficacy. Here, we take steps towards filling the need for such promoters by developing a high-throughput pipeline that goes from genome-based bioinformatic design to rapid testing in vivo. For much of this work, therapeutically interesting Pleiades MiniPromoters (MiniPs; ~4 kb human DNA regulatory elements), previously tested in knock-in mice, were "cut down" to ~2.5 kb and tested in recombinant adeno-associated virus (rAAV), the virus of choice for gene therapy of the central nervous system. To evaluate our methods, we generated 29 experimental rAAV2/9 viruses carrying 19 different MiniPs, which were injected intravenously into neonatal mice to allow broad unbiased distribution, and characterized in neural tissues by X-gal immunohistochemistry for icre, or immunofluorescent detection of GFP. The data showed that 16 of the 19 (84 %) MiniPs recapitulated the expression pattern of their design source. This included expression of: Ple67 in brain raphe nuclei; Ple155 in Purkinje cells of the cerebellum, and retinal bipolar ON cells; Ple261 in endothelial cells of brain blood vessels; and Ple264 in retinal Müller glia. Overall, the methodology and MiniPs presented here represent important advances for basic and preclinical research, and may enable a paradigm shift in gene therapy.

Accuracy of a cone beam computed tomography-guided surgical stent for orthodontic mini-implant placement.

PubMed

Yu, Jae-Jung; Kim, Gyu-Tae; Choi, Yong-Suk; Hwang, Eui-Hwan; Paek, Janghyun; Kim, Seong-Hun; Huang, John C

2012-03-01

To validate the accuracy of a cone-beam computed tomography (CBCT)-guided surgical stent for orthodontic mini-implant (OMI) placement by quantitatively evaluating the difference between CBCT-prescribed and actual position of mini-implants in preoperative and postoperative CBCT images. A surgical stent was fabricated using Teflon-Perfluoroalkoxy, which has appropriate biological x-ray attenuation properties. Polyvinylsiloxane impression material was used to secure the custom-made surgical stent onto swine mandibles. CBCT scanning was done with the stent in place to virtually plan mini-implants using a three-dimensional (3D) software program. An appropriate insertion point was determined using 3D reconstruction data, and the vertical and horizontal angulations were determined using four prescribed angles. A custom-designed surveyor was used to drill a guide hole within the surgical stent as prescribed on the CBCT images for insertion of 32 OMIs. The mandibles with a surgical stent in place were rescanned with CBCT to measure the deviations between the virtual planning data and surgical results. The difference between the prescribed and actual vertical angle was 1.01 ± 7.25, and the horizontal difference was 1.16 ± 6.08. The correlation coefficient confirms that there was no intrarater variability in either the horizontal (R  =  .97) or vertical (R  =  .74) vectors. The surgical stent in this study guides mini-implants to the prescribed position as planned in CBCT. Since the statistical difference was not significant, the surgical stent can be considered to be an accurate guide tool for mini-implant placement in clinical use.

Revisiting the stability of mini-implants used for orthodontic anchorage.

PubMed

Yao, Chung-Chen Jane; Chang, Hao-Hueng; Chang, Jenny Zwei-Chieng; Lai, Hsiang-Hua; Lu, Shao-Chun; Chen, Yi-Jane

2015-11-01

The aim of this study is to comprehensively analyze the potential factors affecting the failure rates of three types of mini-implants used for orthodontic anchorage. Data were collected on 727 mini-implants (miniplates, predrilled titanium miniscrews, and self-drilling stainless steel miniscrews) in 220 patients. The factors related to mini-implant failure were investigated using a Chi-square test for univariate analysis and a generalized estimating equation model for multivariate analysis. The failure rate for miniplates was significantly lower than for miniscrews. All types of mini-implants, especially the self-drilling stainless steel miniscrews, showed decreased stability if the previous implantation had failed. The stability of predrilled titanium miniscrews and self-drilling stainless steel miniscrews were comparable at the first implantation. However, the failure rate of stainless steel miniscrews increased at the second implantation. The univariate analysis showed that the following variables had a significant influence on the failure rates of mini-implants: age of patient, type of mini-implant, site of implantation, and characteristics of the soft tissue around the mini-implants. The generalized estimating equation analysis revealed that mini-implants with miniscrews used in patients younger than 35 years, subjected to orthodontic loading after 30 days and implanted on the alveolar bone ridge, have a significantly higher risk of failure. This study revealed that once the dental surgeon becomes familiar with the procedure, the stability of orthodontic mini-implants depends on the type of mini-implant, age of the patient, implantation site, and the healing time of the mini-implant. Miniplates are a more feasible anchorage system when miniscrews fail repeatedly. Copyright © 2014. Published by Elsevier B.V.

MINI PILOT PLANT FOR DRINKING WATER RESEARCH

EPA Science Inventory

The Water Supply & Water Resources Division (WSWRD) has constructed 2 mini-pilot plant systems used to conduct drinking water research. These two systems each have 2 parallel trains for comparative research. The mini-pilot plants are small conventional drinking water treatment ...

Mini-invasive aortic surgery: personal experience.

PubMed

Spinelli, Francesco; Stilo, Francesco; La Spada, Michele; Benedetto, Filippo; De Caridi, Giovanni; Barillà, David; Giardina, Massimiliano; David, Antonio

2014-01-01

In this study, we retrospectively evaluated our experience in minilaparotomy (MINI) and compared the results with conventional open repair (OPEN). From January 2005 to December 2012, we surgically treated 234 consecutive patients with elective infrarenal abdominal aortic aneurysms, 195 men and 39 women, with a mean age of 74 years. Inclusion criteria for MINI were not ruptured abdominal aortic aneurysm, increased surgical risk, anatomical limits for endovascular repair, no previous surgical invasion of the abdominal cavity, and no requirement for concomitant abdominal surgical invasion. Surgical treatment was OPEN in 113 patients (48.3%) and MINI through an 8- to 14-cm incision in 121 patients (51.7%). Epidural anesthesia has been added in 26.5% and in 19.3% of the MINI and OPEN patients, respectively. Mortality, complications, aortic clamping time, operative time, need for postoperative morphine therapy, time to solid diet, and length of hospital stay were registered. The MINI has been performed in all patients selected, with 72 aortoaortic grafts and 49 aortobisiliac grafts. Early mortality was 1.6% versus 3.5% (P > 0.5); 1-, 3-, and 5-year mortality were 7% versus 9%, 19% versus 22%, and 29% versus 34% (P > 0.5); complications were 12.2% versus 26.6% (P > 0.05); mean (SD) clamping time was 48 (12) versus 44 (14) minutes (P > 0.5); mean (SD) operative time was 218.72 (41.95) versus 191.44 (21.73) minutes (P > 0.025); mean (SD) estimated intraoperative blood loss was 425.64 (85.95) versus 385.30 (72.41) mL (P > 0.1); mean (SD) morphine consumption in the group given epidural and the group not given epidural was 0 (2) and 2 (2) mg intravenously (IV) versus 2 (4) (P < 0.5) and 4 (3) mg IV (P > 0.1); mean (SD) ambulation was 2.1 (0.6) versus 4.1 (2.7) (P < 0.5); mean (SD) time to solid diet was 2.1 (0.4) versus 3.5 (1.6) (P < 0.5); and mean (SD) length of hospital stay was 4.9 (1.64) versus 7.35 (1.95) days (P > 0.05), in the MINI and OPEN groups, respectively

Development of a mini-mobile digital radiography system by using wireless smart devices.

PubMed

Jeong, Chang-Won; Joo, Su-Chong; Ryu, Jong-Hyun; Lee, Jinseok; Kim, Kyong-Woo; Yoon, Kwon-Ha

2014-08-01

The current technologies that trend in digital radiology (DR) are toward systems using portable smart mobile as patient-centered care. We aimed to develop a mini-mobile DR system by using smart devices for wireless connection into medical information systems. We developed a mini-mobile DR system consisting of an X-ray source and a Complementary Metal-Oxide Semiconductor (CMOS) sensor based on a flat panel detector for small-field diagnostics in patients. It is used instead of the systems that are difficult to perform with a fixed traditional device. We also designed a method for embedded systems in the development of portable DR systems. The external interface used the fast and stable IEEE 802.11n wireless protocol, and we adapted the device for connections with Picture Archiving and Communication System (PACS) and smart devices. The smart device could display images on an external monitor other than the monitor in the DR system. The communication modules, main control board, and external interface supporting smart devices were implemented. Further, a smart viewer based on the external interface was developed to display image files on various smart devices. In addition, the advantage of operators is to reduce radiation dose when using remote smart devices. It is integrated with smart devices that can provide X-ray imaging services anywhere. With this technology, it can permit image observation on a smart device from a remote location by connecting to the external interface. We evaluated the response time of the mini-mobile DR system to compare to mobile PACS. The experimental results show that our system outperforms conventional mobile PACS in this regard.

A measurement of the neutral current neutrino-nucleon elastic cross section at MiniBooNE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cox, David Christopher

2008-02-01

The neutral current neutrino-nucleon elastic interaction v N → v N is a fundamental process of the weak interaction ideally suited for characterizing the structure of the nucleon neutral weak current. This process comprises ~18% of neutrino events in the neutrino oscillation experiment, MiniBooNE, ranking it as the experiment's third largest process. Using ~10% of MiniBooNE's available neutrino data, a sample of these events were identified and analyzed to determine the differential cross section as a function of the momentum transfer of the interaction, Q 2. This is the first measurement of a differential cross section with MiniBooNE data. Frommore » this analysis, a value for the nucleon axial mass M A was extracted to be 1.34 ± 0.25 GeV consistent with previous measurements. The integrated cross section for the Q 2 range 0.189 → 1.13 GeV 2 was calculated to be (8.8 ± 0.6(stat) ± 0.2(syst)) x 10 -40 cm 2.« less

Mini-Split Heat Pumps Multifamily Retrofit Feasibility Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dentz, Jordan; Podorson, David; Varshney, Kapil

Mini-split heat pumps can provide space heating and cooling in many climates and are relatively affordable. These and other features make them potentially suitable for retrofitting into multifamily buildings in cold climates to replace electric resistance heating or other outmoded heating systems. This report investigates the suitability of mini-split heat pumps for multifamily retrofits. Various technical and regulatory barriers are discussed and modeling was performed to compare long-term costs of substituting mini-splits for a variety of other heating and cooling options. A number of utility programs have retrofit mini-splits in both single family and multifamily residences. Two such multifamily programsmore » are discussed in detail.« less

Mini-Split Heat Pumps Multifamily Retrofit Feasibility Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dentz, J.; Podorson, D.; Varshney, K.

2014-05-01

Mini-split heat pumps can provide space heating and cooling in many climates and are relatively affordable. These and other features make them potentially suitable for retrofitting into multifamily buildings in cold climates to replace electric resistance heating or other outmoded heating systems. This report investigates the suitability of mini-split heat pumps for multifamily retrofits. Various technical and regulatory barriers are discussed and modeling was performed to compare long-term costs of substituting mini-splits for a variety of other heating and cooling options. A number of utility programs have retrofit mini-splits in both single family and multifamily residences. Two such multifamily programsmore » are discussed in detail.« less

History and current status of mini-invasive thoracic surgery

PubMed Central

He, Jianxing

2011-01-01

Mini-invasive thoracic technique mainly refers to a technique involving the significant reduction of the chest wall access-related trauma. Notably, thoracoscope is the chief representative. The development of thoracoscope technique is characterized by: developing from direct peep to artificial lighting, then combination with image and video technique in equipments; technically developing from diagnostic to therapeutic approaches; developing from simpleness to complexity in application scope; and usually developing together with other techniques. At present, the widely used mini-invasive thoracic surgery refers to the mini-open thoracic surgery performed mainly by using some instruments to control target tissues and organs based on the vision associated with multi-limb coordination, which may be hand-assisted if necessary. The mini-invasive thoracic surgery consists of three approaches including video-assisted thoracic surgery (VATS), video-assisted Hybrid and hand-assisted VATS. So far the mini-invasive thoracic technique has achieved great advances due to the development in instruments of mini-invasive thoracic surgery which has the following features: instruments of mini-invasive thoracic surgery appear to be safe and practical, and have successive improvement and diversification in function; the specific instruments of open surgeries has been successively developed into dedicated instruments of endoscopic surgery; the application of endoscopic mechanical suture device generates faster fragmentation and reconstruction of organ tissues; the specific delicated instruments of endoscopic surgery have rapid development and application; and the simple instruments structurally similar to the conventional instruments are designed according to the mini-incison. In addition, the mini-invasive thoracic technique is widely used in five aspects including diseases of pleura membrane and chest wall, lung diseases, esophageal diseases, mediastinal diseases and heart diseases

Unveiling the X-ray/UV properties of disk winds in active galactic nuclei using broad and mini-broad absorption line quasars

NASA Astrophysics Data System (ADS)

Giustini, M.

2016-05-01

We present the results of the uniform analysis of 46 XMM-Newton observations of six BAL and seven mini-BAL QSOs belonging to the Palomar-Green Quasar catalogue. Moderate-quality X-ray spectroscopy was performed with the EPIC-pn, and allowed to characterise the general source spectral shape to be complex, significantly deviating from a power law emission. A simple power law analysis in different energy bands strongly suggests absorption to be more significant than reflection in shaping the spectra. If allowing for the absorbing gas to be either partially covering the continuum emission source or to be ionised, large column densities of the order of 1022-1024 cm-2 are inferred. When the statistics was high enough, virtually every source was found to vary in spectral shape on various time scales, from years to hours. All in all these observational results are compatible with radiation driven accretion disk winds shaping the spectra of these intriguing cosmic sources.

Mini-Survey of SDSS OIII AGN with Swift

NASA Technical Reports Server (NTRS)

Angelina, Lorella; George, Ian

2007-01-01

There is a common wisdom that every massive galaxy has a massive block hole. However, most of these objects either are not radiating or until recently have been very difficult to detect. The Sloan Digital Sky Survey (SDSS) data, based on the [OIII] line indicate that perhaps up to 20% of all galaxies may be classified as AGN a surprising result that must be checked with independent data. X-ray surveys have revealed that hard X-ray selected AGN show a strong luminosity dependent evolution and their luminosity function (LF) shows a dramatic break towards low Lx (at all z). This is seen for all types of AGN, but is stronger for the broad-line objects. In sharp contrast, the local LF of (optically-selected samples) shows no such break and no differences between narrow and broad-line objects. Assuming both hard X-ray and [OIII] emission are fair indicators of AGN activity, it is important to understand this discrepancy. We present here the results of a mini-survey done with Swift on a selected sample of SDSS selected AGN. The objects have been sampled at different L([OIII]) to check the relation with the Lx observed with Swift.

Does the design of mini slings anchoring systems really matter? A biomechanical comparison between Mini Arc™ and Ophira™.

PubMed

Santos-Souza, R; Rodrigues-Palma, P C; Goulart-Fernandes-Dias, F; Teixeira-Siniscalchi, R; Zanettini-Riccetto, C L

2016-11-01

Currently, a sling implant is the standard treatment for stress urinary incontinence in women. To be effective, they require an adequate anchoring system. The aim of this study is compare biomechanical features of fixation systems of two mini slings models available on the market (Ophira™ and Mini Arc™) through a tensile test. Anchoring devices of each sling were surgically implanted in abdominal wall of 15 rats divided into three groups of five animals which were arranged according to the date of post implant euthanasia on 7, 14 and 30 days. Abdominal walls of rats were extracted on bloc containing the anchoring system and were submitted to a tensile strength test to measure the maximum load and elongation until device avulsion from the tissue. The results were compared using Student test t and a 5% cut off was considered significant. The Ophira™ mini sling fixation system demanded a greater maximum load and developed a longer stretch for avulsion from the implanted site at all moments evaluated (p value less than 0.05). There were significant differences in fixation patterns of the anchoring systems, which were exclusively related to their designs. The Ophira™ mini sling fixation device provided better fixation to the abdominal wall of rats compared to the Mini Arc™ device, even in the late post implant period. Copyright © 2016 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

Reasons for mini-implants failure: choosing installation site should be valued!

PubMed Central

Consolaro, Alberto; Romano, Fábio Lourenço

2014-01-01

Mini-implant loss is often associated with physical and mechanical aspects that result from choosing an inappropriate placement site. It is worth highlighting that: a) Interdental alveolar bone crests are flexible and deformable. For this reason, they may not offer the ideal absolute anchorage. The more cervical the structures, the more delicate they are, thus offering less physical support for mini-implant placement; b) Alveolar bone crests of triangular shape are more deformable, whereas those of rectangular shape are more flexible; c) The bases of the alveolar processes of the maxilla and the mandible are not flexible, for this reason, they are more likely to receive mini-implants; d) The more cervical a mini-implant is placed, the higher the risk of loss; the more apical a mini-implant is placed, the better its prognosis will be; e) 3D evaluations play a major role in planning the use of mini-implants. Based on the aforementioned considerations, the hypotheses about mini-implant loss are as follows: 1) Deflection of maxillary and mandibular alveolar processes when mini-implants are more cervically placed; 2) Mini-implants placed too near the periodontal ligament, with normal intra-alveolar tooth movement; 3) Low bone density, low thickness and low alveolar bone volume; 4) Low alveolar cortical bone thickness; 5) Excessive pressure inducing trabecular bone microfracture; 6) Sites of higher anatomical weakness in the mandible and the maxilla; 7) Thicker gingival tissue not considered when choosing the mini-implant. PMID:24945511

Mini-conference on helicon plasma sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scime, E. E.; Keesee, A. M.; Boswell, R. W.

2008-05-15

The first two sessions of this mini-conference focused attention on two areas of helicon source research: The conditions for optimal helicon source performance and the origins of energetic electrons and ions in helicon source plasmas. The final mini-conference session reviewed novel applications of helicon sources, such as mixed plasma source systems and toroidal helicon sources. The session format was designed to stimulate debate and discussion, with considerable time available for extended discussion.

Congenital hypogonadotropic hypogonadism: implications of absent mini-puberty.

PubMed

Dwyer, Andrew A; Jayasena, Channa N; Quinton, Richard

2016-06-01

The phenomenon known as "mini-puberty" refers to activation of the neonatal hypothalamo-pituitary axis causing serum concentrations of gonadotrophins and testosterone (T) to approach adult male levels. This early neonatal period is a key proliferative window for testicular germ cells and immature Sertoli cells. Although failure to spontaneously initiate (adolescent) puberty is the most evident consequence of a defective gonadotropin-releasing hormone (GnRH) neurosecretory network, absent mini-puberty is also likely to have a major impact on the reproductive phenotype of men with congenital hypogonadotrophic hypogonadism (CHH). Furthermore, the phase of male mini-puberty represents a key window-of-opportunity to identify congenital GnRH deficiency (either isolated CHH, or as part of combined pituitary hormone deficiency) in childhood. Among male neonates exhibiting "red flag" indicators for CHH (i.e. maldescended testes with or without cryptorchidism) a single serum sample (between 4-8 weeks of life) can pinpoint congenital GnRH deficiency far more rapidly and with much greater accuracy than dynamic tests performed in later childhood or adolescence. Potential consequences for missing absent mini-puberty in a male neonate include the lack of monitoring of pubertal progression/lack of progression, and the missed opportunity for early therapeutic intervention. This article will review our current understanding of the mechanisms and clinical consequences of mini-puberty. Furthermore, evidence for the optimal clinical management of patients with absent mini-puberty will be discussed.

Mini AERCam Inspection Robot for Human Space Missions

NASA Technical Reports Server (NTRS)

Fredrickson, Steven E.; Duran, Steve; Mitchell, Jennifer D.

2004-01-01

The Engineering Directorate of NASA Johnson Space Center has developed a nanosatellite-class free-flyer intended for future external inspection and remote viewing of human spacecraft. The Miniature Autonomous Extravehicular Robotic Camera (Mini AERCam) technology demonstration unit has been integrated into the approximate form and function of a flight system. The spherical Mini AERCam free flyer is 7.5 inches in diameter and weighs approximately 10 pounds, yet it incorporates significant additional capabilities compared to the 35 pound, 14 inch AERCam Sprint that flew as a Shuttle flight experiment in 1997. Mini AERCam hosts a full suite of miniaturized avionics, instrumentation, communications, navigation, imaging, power, and propulsion subsystems, including digital video cameras and a high resolution still image camera. The vehicle is designed for either remotely piloted operations or supervised autonomous operations including automatic stationkeeping and point-to-point maneuvering. Mini AERCam is designed to fulfill the unique requirements and constraints associated with using a free flyer to perform external inspections and remote viewing of human spacecraft operations. This paper describes the application of Mini AERCam for stand-alone spacecraft inspection, as well as for roles on teams of humans and robots conducting future space exploration missions.

Free 'mini' groin flap for digital resurfacing.

PubMed

Tare, M; Ramakrishnan, V

2009-06-01

Ten cases of post-traumatic skin and soft tissue loss over the digits were resurfaced by free 'mini' groin flap. Five patients had defects of the dorsum of the digit, three had proximal palmar defects, one patient had circumferential skin loss and one had multiple digital injuries. The flap was harvested from the contralateral groin using a two-team approach. The average size of the flap was 5.5 x 4.75 cm and the mean operating time was 2.45 hrs. All patients had physiotherapy within 48-72 hrs. There were no flap losses. Six patients were happy with the cosmetic result and did not require any further debulking. We recommend free tissue transfer for digital resurfacing specifically in moderate to large dorsal defects, proximal volar defects, circumferential skin loss and multiple digit injuries.

Mini-beam collimator enables microcrystallography experiments on standard beamlines

PubMed Central

Fischetti, Robert F.; Xu, Shenglan; Yoder, Derek W.; Becker, Michael; Nagarajan, Venugopalan; Sanishvili, Ruslan; Hilgart, Mark C.; Stepanov, Sergey; Makarov, Oleg; Smith, Janet L.

2009-01-01

The high-brilliance X-ray beams from undulator sources at third-generation synchrotron facilities are excellent tools for solving crystal structures of important and challenging biological macromolecules and complexes. However, many of the most important structural targets yield crystals that are too small or too inhomogeneous for a ‘standard’ beam from an undulator source, ∼25–50 µm (FWHM) in the vertical and 50–100 µm in the horizontal direction. Although many synchrotron facilities have microfocus beamlines for other applications, this capability for macromolecular crystallography was pioneered at ID-13 of the ESRF. The National Institute of General Medical Sciences and National Cancer Institute Collaborative Access Team (GM/CA-CAT) dual canted undulator beamlines at the APS deliver high-intensity focused beams with a minimum focal size of 20 µm × 65 µm at the sample position. To meet growing user demand for beams to study samples of 10 µm or less, a ‘mini-beam’ apparatus was developed that conditions the focused beam to either 5 µm or 10 µm (FWHM) diameter with high intensity. The mini-beam has a symmetric Gaussian shape in both the horizontal and vertical directions, and reduces the vertical divergence of the focused beam by 25%. Significant reduction in background was achieved by implementation of both forward- and back-scatter guards. A unique triple-collimator apparatus, which has been in routine use on both undulator beamlines since February 2008, allows users to rapidly interchange the focused beam and conditioned mini-beams of two sizes with a single mouse click. The device and the beam are stable over many hours of routine operation. The rapid-exchange capability has greatly facilitated sample screening and resulted in several structures that could not have been obtained with the larger focused beam. PMID:19240333

Complete overdentures retained by mini implants: A systematic review.

PubMed

Lemos, Cleidiel Aparecido Araujo; Verri, Fellippo Ramos; Batista, Victor Eduardo de Souza; Júnior, Joel Ferreira Santiago; Mello, Caroline Cantieri; Pellizzer, Eduardo Piza

2017-02-01

The purpose of this systematic review was to evaluate the use of mini implants to retain complete overdentures in terms of survival rates of mini implants, marginal bone loss, satisfaction, and quality of life. This report followed the PRISMA Statement and PICO question. This review has been registered at PROSPERO under the number CRD42016036141. Two independent reviewers performed a comprehensive search of studies published until September 2016 and listed in the PubMed/MEDLINE, Embase, and The Cochrane Library databases. The focused question was: is the use of mini implants feasible for prosthodontic rehabilitation with complete overdentures? The 24 studies selected for review evaluated 1273 patients whose mean age was 65.93 years; these patients had received 2494 mini implants and 386 standard implants for retaining overdenture prosthesis. The mean follow-up time was 2.48 years (range: 1-7 years). There was a higher survival rate of mini implants (92.32%). More frequent failures for maxillary (31.71%) compared with mandibular arches (4.89%). The majority of studies revealed marginal bone loss values similar to those of standard implants (<1.5mm). All studies verified an increase in satisfaction and quality of life after rehabilitation treatment with mini dental implants. The present systematic review indicates that the use of mini implants for retaining overdenture prosthesis is considered an alternative treatment when standard treatment is not possible, since it presents high survival rates, acceptable marginal bone loss, and improvements in variables related to satisfaction and quality of life. Based on the results of this study, the use of a minimum 4 and 6 mini implants can be considered a satisfactory treatment option for rehabilitation of the mandibular and maxillary arches respectively with a complete overdenture. Copyright © 2016. Published by Elsevier Ltd.

MiniAERCam Ranging

NASA Technical Reports Server (NTRS)

Talley, Tom

2003-01-01

Johnson Space Center (JSC) is designing a small, remotely controlled vehicle that will carry two color and one black and white video cameras in space. The device will launch and retrieve from the Space Vehicle and be used for remote viewing. Off the shelf cellular technology is being used as the basis for communication system design. Existing plans include using multiple antennas to make simultaneous estimates of the azimuth of the MiniAERCam from several sites on the Space Station and use triangulation to find the location of the device. Adding range detection capability to each of the nodes on the Space Vehicle would allow an estimate of the location of the MiniAERCam to be made at each Communication And Telemetry Box (CATBox) independent of all the other communication nodes. This project will investigate the techniques used by the Global Positioning System (GPS) to achieve accurate positioning information and adapt those strategies that are appropriate to the design of the CATBox range determination system.

Quasi-periodic Behavior of Mini-disks in Binary Black Holes Approaching Merger

NASA Astrophysics Data System (ADS)

Bowen, Dennis B.; Mewes, Vassilios; Campanelli, Manuela; Noble, Scott C.; Krolik, Julian H.; Zilhão, Miguel

2018-01-01

We present the first magnetohydrodynamic simulation in which a circumbinary disk around a relativistic binary black hole feeds mass to individual accretion disks (“mini-disks”) around each black hole. Mass flow through the accretion streams linking the circumbinary disk to the mini-disks is modulated quasi-periodically by the streams’ interaction with a nonlinear m = 1 density feature, or “lump,” at the inner edge of the circumbinary disk: the stream supplying each mini-disk comes into phase with the lump at a frequency 0.74 times the binary orbital frequency. Because the binary is relativistic, the tidal truncation radii of the mini-disks are not much larger than their innermost stable circular orbits; consequently, the mini-disks’ inflow times are shorter than the conventional estimate and are comparable to the stream modulation period. As a result, the mini-disks are always in inflow disequilibrium, with their masses and spiral density wave structures responding to the stream’s quasi-periodic modulation. The fluctuations in each mini-disk’s mass are so large that as much as 75% of the total mini-disk mass can be contained within a single mini-disk. Such quasi-periodic modulation of the mini-disk structure may introduce distinctive time-dependent features in the binary’s electromagnetic emission.

The photocatalytic properties of hollow (GaN)1-x(ZnO)x composite nanofibers synthesized by electrospinning

NASA Astrophysics Data System (ADS)

Wang, Ding; Zhang, Minglu; Zhuang, Huaijuan; Chen, Xu; Wang, Xianying; Zheng, Xuejun; Yang, Junhe

2017-02-01

(GaN)1-x(ZnO)x composite nanofibers with hollow structure were prepared by initial electrospinning, and the subsequent calcination and nitridation. The structure and morphology characteristics of samples were investigated by X-ray diffraction (XRD), field-emission scanning electron microscopy (FE-SEM), energy dispersive X-ray spectroscopy (EDS) and transmission electron microscopy (TEM). The characterization results showed the phase transition from ZnGa2O4 to (GaN)1-x(ZnO)x solid-solution under ammonia atmosphere. The preparation conditions were explored and the optimum nitridation temperature and holding time are 750 °C and 2 h, respectively. The photocatalytic properties of (GaN)1-x(ZnO)x with different Ga:Zn atomic ratios were investigated by degrading Rhodamine B under the visible light irradiation. The photocatalytic activity sequence is (GaN)1-x(ZnO)x (Ga:Zn = 1:2) > (GaN)1-x(ZnO)x (Ga:Zn = 1:3) > ZnO nanofibers > (GaN)1-x(ZnO)x (Ga:Zn = 1:4) > (GaN)1-x(ZnO)x (Ga:Zn = 1:1). The photocatalytic mechanism of the (GaN)1-x(ZnO)x hollow nanofibers was further studied by UV-vis diffuse reflectance spectra. The excellent photocatalytic performance of (GaN)1-x(ZnO)x hollow nanofibers was attributed to the narrow band gap and high surface area of porous nanofibers with hollow structure. ja:tail>:article>

Miniaturized Autonomous Extravehicular Robotic Camera (Mini AERCam)

NASA Technical Reports Server (NTRS)

Fredrickson, Steven E.

2001-01-01

The NASA Johnson Space Center (JSC) Engineering Directorate is developing the Autonomous Extravehicular Robotic Camera (AERCam), a low-volume, low-mass free-flying camera system . AERCam project team personnel recently initiated development of a miniaturized version of AERCam known as Mini AERCam. The Mini AERCam target design is a spherical "nanosatellite" free-flyer 7.5 inches in diameter and weighing 1 0 pounds. Mini AERCam is building on the success of the AERCam Sprint STS-87 flight experiment by adding new on-board sensing and processing capabilities while simultaneously reducing volume by 80%. Achieving enhanced capability in a smaller package depends on applying miniaturization technology across virtually all subsystems. Technology innovations being incorporated include micro electromechanical system (MEMS) gyros, "camera-on-a-chip" CMOS imagers, rechargeable xenon gas propulsion system , rechargeable lithium ion battery, custom avionics based on the PowerPC 740 microprocessor, GPS relative navigation, digital radio frequency communications and tracking, micropatch antennas, digital instrumentation, and dense mechanical packaging. The Mini AERCam free-flyer will initially be integrated into an approximate flight-like configuration for demonstration on an airbearing table. A pilot-in-the-loop and hardware-in-the-loop simulation to simulate on-orbit navigation and dynamics will complement the airbearing table demonstration. The Mini AERCam lab demonstration is intended to form the basis for future development of an AERCam flight system that provides beneficial on-orbit views unobtainable from fixed cameras, cameras on robotic manipulators, or cameras carried by EVA crewmembers.

Production of extended release mini-tablets using directly compressible grades of HPMC.

PubMed

Mohamed, Faiezah A A; Roberts, Matthew; Seton, Linda; Ford, James L; Levina, Marina; Rajabi-Siahboomi, Ali R

2013-11-01

Hypromellose (HPMC) has been previously used to control drug release from mini-tablets. However, owing to poor flow, production of mini-tablets containing high HPMC levels is challenging. Directly compressible (DC) HPMC grades have been developed by Dow Chemical Company. To compare the properties of HPMC DC (METHOCEL™ K4M and K100M) with regular (REG) HPMC grades. Particle size distribution and flowability of HPMC REG and DC were evaluated. 3 mm mini-tablets, containing hydrocortisone or theophylline as model drugs and 40% w/w HPMC DC or REG were produced. Mini-tablets containing HPMC DC grades were manufactured using a rotary press simulator at forces between 2-4 kN and speeds of 5, 10, 15 or 20 rpm. Mini-tablets containing HPMC REG were produced manually. The improved flowability of HPMC DC grades, which have a narrower particle size distribution and larger particle sizes, meant that simulated large scale production of mini-tablets with good weight uniformity (CV 1.79-4.65%) was feasible. It was not possible to automatically manufacture mini-tablets containing HPMC REG due to the poor flowability of the formulations. Drug release from mini-tablets comprising HPMC DC and REG were comparable. Mini-tablets containing HPMC DC illustrated a higher tensile strength compared to mini-tablets made with HPMC REG. Mini-tablets produced with HPMC DC at different compression speeds had similar drug release profiles. Production of extended release mini-tablets was successfully achieved when HPMC DC was used. Drug release rate was not influenced by the different HPMC DC grades (K4M or K100M) or production speed.

Designing a Microhydraulically driven Mini robotic Squid

DTIC Science & Technology

2016-05-20

applications for microrobots include remote monitoring, surveillance, search and rescue, nanoassembly, medicine, and in-vivo surgery . Robotics platforms...Secretary of Defense for Research and Engineering. Designing a Microhydraulically-driven Mini- robotic Squid by Kevin Dehan Meng B.S., U.S. Air...Committee on Graduate Students 2 Designing a Microhydraulically-driven Mini- robotic Squid by Kevin Dehan Meng Submitted to the Department

Cost analysis of a mini-facet heliostat

NASA Astrophysics Data System (ADS)

Hall, Colin; Pratt, Rodney; Farrant, David; Corsi, Clotilde; Pye, John; Coventry, Joe

2017-06-01

A significant problem with conventional heliostats is off-axis astigmatism, which increases the spot size at the central receiver, limiting the temperature and efficiency of solar thermal systems. Inspired by low-cost mini-actuators used for car wing mirrors, we examine the economic feasibility of a heliostat with individually adjustable mini-facets to correct astigmatic effects, and we compare three alternative tracking configurations.

Orthodontic mechanics using mini-implant measured by FBG

NASA Astrophysics Data System (ADS)

Trannin, Pamela G.; Milczewski, Maura S.; de Oliveira, Walmir; Guariza Filho, Odilon; Lopes, Stephani C. P. S.; Kalinowski, Hypolito J.

2015-07-01

The magnitude of the force generated during orthodontic mechanics anchored in mini-implant in a maxilla model was analyzed. Data was collected during the insertion of the mini-implant and at the moment of applying forces to the structure of the maxilla and dentition. To obtain quantitative results, the Fibre Bragg Gratings (FBG) were inserted in an elastomeric material reproducing a maxilla model. It was observed levels of forces of approximately 3,78N next to the root of first premolar by the insertion of the mini-implant and different levels of the force to different orthodontic mechanics applied on the dental system.

Enhancement of the forced convective heat transfer on mini pin fin heat sinks with micro spiral fins

NASA Astrophysics Data System (ADS)

Khonsue, Osot

2018-02-01

This research is an experimental study on the characteristics of heat transfer and pressure drop in mini heat sinks using air as the working fluid. The experiments were performed under a constant heat flux ranging from 9.132-13.698 kW/m2 and the air Reynolds number range 322-1982. Three different types of mini heat sinks were rectangle pin fins, cylindrical pin fins, and spiral pin fins with 36x28x9 mm and 5 mm fins high. There were 63 fins altogether and all were made of aluminum. The results showed that the characteristics of the temperature of heat sink of spiral pin fins was the least. Meanwhile the average heat transfer coefficient and Nusselt number of spiral pin fins were the most . Regarding the pressure drop, the rectangular pin fins was the least. The results of this study can be used to guide the design and development of electronic devices cooling system with forced convective heat transfer for higher performance in the future.

Comparison of success rates of orthodontic mini-screws by the insertion method.

PubMed

Kim, Jung Suk; Choi, Seong Hwan; Cha, Sang Kwon; Kim, Jang Han; Lee, Hwa Jin; Yeom, Sang Seon; Hwang, Chung Ju

2012-10-01

The aim of this study was to compare the success rates of the manual and motor-driven mini-screw insertion methods according to age, gender, length of mini-screws, and insertion sites. We retrospectively reviewed 429 orthodontic mini-screw placements in 286 patients (102 in men and 327 in women) between 2005 and 2010 at private practice. Age, gender, mini-screw length, and insertion site were cross-tabulated against the insertion methods. The Cochran-Mantel-Haenszel test was performed to compare the success rates of the 2 insertion methods. The motor-driven method was used for 228 mini-screws and the manual method for the remaining 201 mini-screws. The success rates were similar in both men and women irrespective of the insertion method used. With respect to mini-screw length, no difference in success rates was found between motor and hand drivers for the 6-mm-long mini-screws (68.1% and 69.5% with the engine driver and hand driver, respectively). However, the 8-mm-long mini-screws exhibited significantly higher success rates (90.4%, p < 0.01) than did the 6-mm-long mini-screws when placed with the engine driver. The overall success rate was also significantly higher in the maxilla (p < 0.05) when the engine driver was used. Success rates were similar among all age groups regardless of the insertion method used. Taken together, the motor-driven insertion method can be helpful to get a higher success rate of orthodontic mini-screw placement.

Impact of implant design on primary stability of orthodontic mini-implants.

PubMed

Wilmes, Benedict; Ottenstreuer, Stephanie; Su, Yu-Yu; Drescher, Dieter

2008-01-01

Skeletal anchorage with mini-implants has greatly broadened the treatment possibilities in orthodontics over the last few years. To reduce implant failure rates, it is advisable to obtain adequate primary stability. The aim of this study was to quantitatively analyze the impact of implant design and dimension on primary stability. Forty-two porcine iliac bone segments were prepared and embedded in resin. To evaluate the primary stability, we documented insertion torques of the following mini-implants: Aarhus Screw, AbsoAnchor, LOMAS, Micro-Anchorage-System, ORLUS and Spider Screw. In each bone, five Dual Top Screws were inserted for reference purposes to achieve comparability among the specimens. We observed wide variation in insertion torques and hence primary stability, depending on mini-implant design and dimension; the great impact that mini-implant diameter has on insertion torques was particularly conspicuous. Conical mini-implants achieved higher primary stabilities than cylindrical designs. The diameter and design of the mini-implant thread have a distinctive impact on primary stability. Depending on the region of insertion and local bone quality, the choice of the mini-implant design and size is crucial to establish sufficient primary stability.

Space X1 First Entry Sample

NASA Technical Reports Server (NTRS)

James, John T.

2012-01-01

One mini-grab sample container (m-GSC) was returned aboard Space X1 because of the importance of quickly knowing first-entry conditions in this new commercial module. This sample was analyzed alongside samples of the portable clean room (PCR) used in the Space X complex at KSC. The recoveries of C-13-acetone, fluorobenzene, and chlorobenzene from the GSCs averaged 130, 129, and 132 %, respectively.

Some Issues in Programming Multi-Mini-Processors

DTIC Science & Technology

1975-01-01

Hardware ^nd software are to be combined optimally to perform that specialized task. This in essence is the stategy followed by the BBN group in...large memory is directly addressable. MIXED SOLUTIONS The most promising approach appears to involve mixing several of the previous solutions...mini- or micro-computers. Possibly the problem will be solved by avoiding it. Some new minis are appearing on the market now with large physical

Mini-Concerts: Creating Space for Student-Initiated Performance

ERIC Educational Resources Information Center

Gifford, Cody; Johnson, Erik

2015-01-01

Mini-concerts are regularly occurring, low-stakes curricular events in the classroom where students perform music of their choice for their peers. An idea generated by music educators in domestic and international K-12 schools who strive to meet the needs of diverse student populations, mini-concerts have helped generate student excitement and…

Use of mini-refuges by female northern pintails wintering in southwestern Louisiana

USGS Publications Warehouse

Cox, Robert R.; Afton, Alan D.

1998-01-01

The Gulf Coast Joint Venture of the North American Waterfowl Management Plan began contracting private agricultural lands (hereafter mini-refuges) in 1988 to expand existing sanctuaries for northern pintails (Anas acuta) in southwestern Louisiana. Previous research suggested that mini-refuges may prove more attractive to pintails than permanent, open-water pools (pools) on refuges because mini-refuges provide sanctuary and food during the day, whereas pools generally provide only sanctuary (Rave and Cordes 1993). We used radiotelemetry to compare diel use of mini-refuges and pools (Lacassine Pool and Amoco Pool) by female pintails in southwestern Louisiana during winters of 1991-1992 and 1992-1993. We examined variation in use of these areas in relation to female age (immature or adult), time period (prehunting season, first hunting season, time between split hunting seasons, second hunting season, and posthunting season), and winter (1991-1992 and 1992-1993). Diurnal use of min-refuges and pools differed among time periods, but differences were not consistent between winters. Mini-refuges accounted for <2% of diurnal use by pintails in 7 of 10 time-period and winter comparisons. Diurnal use of mini-refuges was lower than that of Lacassine Pool in 8 of 10 time-period and winter comparisons. Diurnal use of mini-refuges was lower than tha of Amoco pool during first hunting season in 1992-1993, but use of these areas did not differ within other time periods and winters. Nocturnal use of mini-refuges and pools did not differ in relation to female age, time period, winter, or individual bird. Nocturnal use of mini-refuges did not differ from that of Lacassine Pool. In contrast to predictions and findings by Rave and Cordes (1993), we found that: (1) female pintails did not use mini-refuges more than pools, and (2) female pintails used mini-refuges at night. We believe that use of mini-refuges by pintails could be increased if mini-refuges were (1) located in areas of

Reading Mini-Lessons: An Instructional Practice for Meaning Centered Reading Programs.

ERIC Educational Resources Information Center

Barrentine, Shelby; And Others

1995-01-01

Mini-lessons (brief, informative explanations that demonstrate what readers do) are a key instructional practice in meaning centered reading programs. The content of the mini-lessons is determined by the needs of learners. In procedural mini-lessons, teachers explain the steps for successfully completing a task or performing a reading-related…

Update on the MiniCLEAN dark matter experiment

DOE PAGES

Rielage, K.; Akashi-Ronquest, M.; Bodmer, M.; ...

2015-03-24

The direct search for dark matter is entering a period of increased sensitivity to the hypothetical Weakly Interacting Massive Particle (WIMP). One such technology that is being examined is a scintillation only noble liquid experiment, MiniCLEAN. MiniCLEAN utilizes over 500 kg of liquid cryogen to detect nuclear recoils from WIMP dark matter and serves as a demonstration for a future detector of order 50 to 100 tonnes. The liquid cryogen is interchangeable between argon and neon to study the A² dependence of the potential signal and examine backgrounds. MiniCLEAN utilizes a unique modular design with spherical geometry to maximize themore » light yield using cold photomultiplier tubes in a single-phase detector. Pulse shape discrimination techniques are used to separate nuclear recoil signals from electron recoil backgrounds. MiniCLEAN will be spiked with additional ³⁹Ar to demonstrate the effective reach of the pulse shape discrimination capability. Assembly of the experiment is underway at SNOLAB and an update on the project is given.« less

A simple three-dimensional stent for proper placement of mini-implant

PubMed Central

2013-01-01

Background This paper deals with the fabrication of a three-dimensional stent which is simple in design but provides an accurate placement of a mini-implant in three planes of space, namely, sagittal (root proximity), vertical (attached gingiva/alveolar mucosa) and transverse (angulation). Findings The stent is made of 0.018 × 0.025 in. stainless steel archwire which consists of a ‘u loop’ angulated at 20°, a vertical limb, a horizontal limb and a stop. The angulation of the ‘u’ helps in the placement of the mini-implant at 70° to the long axis of the tooth. The vertical height is determined such that the mini-implant is placed at the mucogingival junction. The mini-implant is placed with the aid of the stent, and its angulation and proximity to the adjacent roots are checked with a cone beam computed tomography image. The cone beam computed tomography image showed the mini-implant at an angle of 70° to the long axis of the tooth. There is no contact between mini-implant and the roots of the adjacent teeth. Conclusion This stent is simple, easy to fabricate, cost-effective, and provides ease of insertion/removal, and three-dimensional orientation of the mini-implant. PMID:24326158

Mini Array for TLE Detection

NASA Astrophysics Data System (ADS)

Fullekrug, M.; Liu, Z.; Koh, K.; Mezentsev, A.; Pedeboy, S.; Soula, S.; Sugier, J.; Enno, S. E.; Rycroft, M. J.

2016-12-01

Transient Luminous Events (TLEs) can generate electromagnetic radiation at frequencies 100 kHz (Qin et al., 2012, Fullekrug et al., 2013) and <1 kHz (Pasko et al., GRL, 1998, Cummer et al., GRL, 1998)as a result of the splitting and exponential growth of streamer discharges (Pasko, JGR, 2010, McHarg, JGR, 2010). The electromagnetic radiation results from the coherent superposition of the very weak signalsfrom thousands of small scale streamer discharges at 40 km height for frequencies 100 kHz and at 80 km height for frequencies <1 kHz. It seems therefore plausible that TLEs can also generate electromagnetic waves at intermediate heights, e.g. 60 km with frequencies between 1-100 kHz, e.g., 10 kHz. However, this frequency range is dominated by the powerful electromagnetic radiation from return strokes and it is hence commonly thought that this radiation can not easily be detectedwith single radio receivers. This study proposes to search for electromagnetic radiation from TLEsabove thunderclouds by use of a mini array that has the ability to determine the elevation angle toward the radiation source. Mini arrays with small apertures are used for infrasonic and seismic studies to determine source mechanisms and properties of the medium through which the waves propagate. For the detection of electromagneticradiation, the array processing is adapted for the fast propagationat the speed of light. Here we report for the first time the detection and mapping of distant lightning strokes in the sky with a mini array located near Bath in the UK. The array has a baseline to wavelength ratio 4.2 10^{-2} to record electromagnetic waves from 2-18 kHz. It is found that the mini array detects 69 lightning strokes per second from cloud-to-ground and in-cloud discharges, even though the parent thunderstorms are 900-1,100 km away and a rigorous selection criterion based on the spatial coherency of the electromagnetic source field across the array is used. About 14% of the lightning

Systemic levels of metallic ions released from orthodontic mini-implants.

PubMed

de Morais, Liliane Siqueira; Serra, Glaucio Guimarães; Albuquerque Palermo, Elisabete Fernandes; Andrade, Leonardo Rodrigues; Müller, Carlos Alberto; Meyers, Marc André; Elias, Carlos Nelson

2009-04-01

Orthodontic mini-implants are a potential source of metallic ions to the human body because of the corrosion of titanium (Ti) alloy in body fluids. The purpose of this study was to gauge the concentration of Ti, aluminum (Al), and vanadium (V), as a function of time, in the kidneys, livers, and lungs of rabbits that had Ti-6Al-4V alloy orthodontic mini-implants placed in their tibia. Twenty-three New Zealand rabbits were randomly divided into 4 groups: control, 1 week, 4 weeks, and 12 weeks. Four orthodontic mini-implants were placed in the left proximal tibia of 18 rabbits. Five control rabbits had no orthodontic mini-implants. After 1, 4, and 12 weeks, the rabbits were killed, and the selected tissues were extracted and prepared for analysis by graphite furnace atomic absorption spectrophotometry. Low amounts of Ti, Al, and V were detectable in the 1-week, 4-weeks, and 12-weeks groups, confirming that release of these metals from the mini-implants occurs, with diffusion and accumulation in remote organs. Despite the tendency of ion release when using the Ti alloy as orthodontic mini-implants, the amounts of metals detected were significantly below the average intake of these elements through food and drink and did not reach toxic concentrations.

Comparison of Clinical and Radiologic Results of Mini-Open Transforaminal Lumbar Interbody Fusion and Extreme Lateral Interbody Fusion Indirect Decompression for Degenerative Lumbar Spondylolisthesis

PubMed Central

Gen, Hogaku; Sakuma, Yoshio; Koshika, Yasuhide

2018-01-01

Study Design Retrospective study. Purpose In this study, we compared the postoperative outcomes of extreme lateral interbody fusion (XLIF) indirect decompression with that of mini-open transforaminal lumbar interbody fusion (TLIF) in patients with lumbar degenerative spondylolisthesis. Overview of Literature There are very few reports examining postoperative results of XLIF and minimally invasive TLIF for degenerative lumbar spondylolisthesis, and no reports comparing XLIF and mini-open TLIF. Methods Forty patients who underwent 1-level spinal fusion, either by XLIF indirect decompression (X group, 20 patients) or by mini-open TLIF (T group, 20 patients), for treatment of lumbar degenerative spondylolisthesis were included in this study. Invasiveness of surgery was evaluated on the basis of surgery time, blood loss, hospitalization period, and perioperative complications. The Japanese Orthopedic Association Back Pain Evaluation Questionnaire (JOABPEQ), disc angle (DA), disc height (DH), and slipping length (SL) were evaluated before surgery, immediately after surgery, and at 12 months after surgery. Cross-sectional spinal canal area (CSA) was also measured before surgery and at 1 month after surgery. Results There was no significant difference between the groups in terms of surgery time or hospitalization period; however, X group showed a significant decrease in blood loss (p<0.001). Serious complications were not observed in either group. In clinical assessment, no significant differences were observed between the groups with regard to the JOABPEQ results. The change in DH at 12 months after surgery increased significantly in the X group (p<0.05), and the changes in DA and SL were not significantly different between the two groups. The change in CSA was significantly greater in the T group (p<0.001). Conclusions Postoperative clinical results were equally favorable for both procedures; however, in comparison with mini-open TLIF, less blood loss and greater

Comparison of Clinical and Radiologic Results of Mini-Open Transforaminal Lumbar Interbody Fusion and Extreme Lateral Interbody Fusion Indirect Decompression for Degenerative Lumbar Spondylolisthesis.

PubMed

Kono, Yutaka; Gen, Hogaku; Sakuma, Yoshio; Koshika, Yasuhide

2018-04-01

Retrospective study. In this study, we compared the postoperative outcomes of extreme lateral interbody fusion (XLIF) indirect decompression with that of mini-open transforaminal lumbar interbody fusion (TLIF) in patients with lumbar degenerative spondylolisthesis. There are very few reports examining postoperative results of XLIF and minimally invasive TLIF for degenerative lumbar spondylolisthesis, and no reports comparing XLIF and mini-open TLIF. Forty patients who underwent 1-level spinal fusion, either by XLIF indirect decompression (X group, 20 patients) or by mini-open TLIF (T group, 20 patients), for treatment of lumbar degenerative spondylolisthesis were included in this study. Invasiveness of surgery was evaluated on the basis of surgery time, blood loss, hospitalization period, and perioperative complications. The Japanese Orthopedic Association Back Pain Evaluation Questionnaire (JOABPEQ), disc angle (DA), disc height (DH), and slipping length (SL) were evaluated before surgery, immediately after surgery, and at 12 months after surgery. Cross-sectional spinal canal area (CSA) was also measured before surgery and at 1 month after surgery. There was no significant difference between the groups in terms of surgery time or hospitalization period; however, X group showed a significant decrease in blood loss ( p <0.001). Serious complications were not observed in either group. In clinical assessment, no significant differences were observed between the groups with regard to the JOABPEQ results. The change in DH at 12 months after surgery increased significantly in the X group ( p <0.05), and the changes in DA and SL were not significantly different between the two groups. The change in CSA was significantly greater in the T group ( p <0.001). Postoperative clinical results were equally favorable for both procedures; however, in comparison with mini-open TLIF, less blood loss and greater correction of DH were observed in XLIF.

Analysis, design, fabrication and testing of the mini-Brayton rotating unit (Mini-BRU). Volume 1: Text and tables

NASA Technical Reports Server (NTRS)

Dobler, F. X.

1978-01-01

A 500 to 2100 watt power output Mini-Brayton Rotating Unit (Mini-BRU)was analyzed, designed, fabricated and tested. Performance and test data for the various components is included. Components tested include the 2.12 in. diameter compressor, the 2.86 in. diameter turbine, the Rice alternator and the cantilevered foil-type journal and thrust bearings. Also included are results on the fabrication of a C-103 turbine plenum/nozzle assembly and on offgassing of the organic materials in the alternator stator.

Refining MARGINS Mini-Lessons Using Classroom Observations

NASA Astrophysics Data System (ADS)

Iverson, E. A.; Manduca, C. A.; McDaris, J. R.; Lee, S.

2009-12-01

One of the challenges that we face in developing teaching materials or activities from research findings is testing the materials to determine that they work as intended. Traditionally faculty develop material for their own class, notice what worked and didn’t, and improve them the next year. However, as we move to a community process of creating and sharing teaching materials, a community-based process for testing materials is appropriate. The MARGINS project has piloted such a process for testing teaching materials and activities developed as part of its mini-lesson project (http://serc.carleton.edu/margins/index.html). Building on prior work developing mechanisms for community review of teaching resources (e.g. Kastens, 2002; Hancock and Manduca, 2005; Mayhew and Hall, 2007), the MARGINS evaluation team developed a structured classroom observation protocol. The goals of field testing are to a) gather structured, consistent feedback for the lesson authors based on classroom use; b) guide reviewers of these lessons to reflect on research-based educational practice as a framework for their comments; c) collect information on the data and observations that the reviewer used to underpin their review; d) determine which mini-lessons are ready to be made widely available on the website. The protocol guides faculty observations on why they used the activity, the effectiveness of the activity in their classroom, the success of the activity in leading to the desired learning, and what other faculty need to successfully use the activity. Available online (http://serc.carleton.edu/margins/protocol.html), the protocol can be downloaded and completed during instruction with the activity. In order to encourage review of mini-lessons using the protocol, a workshop focused on review and revision of activities was held in May 2009. In preparation for the workshop, 13 of the 28 participants chose to field test a mini-lesson prior to the workshop and reported that they found this

Comparative analysis of numerical and experimental data of orthodontic mini-implants.

PubMed

Chatzigianni, Athina; Keilig, Ludger; Duschner, Heinz; Götz, Hermann; Eliades, Theodore; Bourauel, Christoph

2011-10-01

The purpose of this study was to compare numerical simulation data derived from finite element analysis (FEA) to experimental data on mini-implant loading. Nine finite element (FE) models of mini-implants and surrounding bone were derived from corresponding experimental specimens. The animal bone in the experiment consisted of bovine rib. The experimental groups were based on implant type, length, diameter, and angle of insertion. One experimental specimen was randomly selected from each group and was digitized in a microCT scanner. The FE models consisted of bone pieces containing Aarhus mini-implants with dimensions 1.5 × 7 mm and 1.5 × 9 mm or LOMAS mini-implants (dimensions 1.5 × 7 mm, 1.5 × 9 mm, and 2 × 7 mm). Mini-implants were inserted in two different ways, perpendicular to the bone surface or at 45 degrees to the direction of the applied load. Loading and boundary conditions in the FE models were adjusted to match the experimental situation, with the force applied on the neck of the mini-implants, along the mesio-distal direction up to a maximum of 0.5 N. Displacement and rotation of mini-implants after force application calculated by FEA were compared to previously recorded experimental deflections of the same mini-implants. Analysis of data with the Altman-Bland test and the Youden plot demonstrated good agreement between numerical and experimental findings (P = not significant) for the models selected. This study provides further evidence of the appropriateness of the FEA as an investigational tool in relevant research.

A mini-microscope for in situ monitoring of cells.

PubMed

Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R; Hamilton, Geraldine A; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E; Khademhosseini, Ali

2012-10-21

A mini-microscope was developed for in situ monitoring of cells by modifying off-the-shelf components of a commercial webcam. The mini-microscope consists of a CMOS imaging module, a small plastic lens and a white LED illumination source. The CMOS imaging module was connected to a laptop computer through a USB port for image acquisition and analysis. Due to its compact size, 8 × 10 × 9 cm, the present microscope is portable and can easily fit inside a conventional incubator, and enables real-time monitoring of cellular behaviour. Moreover, the mini-microscope can be used for imaging cells in conventional cell culture flasks, such as Petri dishes and multi-well plates. To demonstrate the operation of the mini-microscope, we monitored the cellular migration of mouse 3T3 fibroblasts in a scratch assay in medium containing three different concentrations of fetal bovine serum (5, 10, and 20%) and demonstrated differential responses depending on serum levels. In addition, we seeded embryonic stem cells inside poly(ethylene glycol) microwells and monitored the formation of stem cell aggregates in real time using the mini-microscope. Furthermore, we also combined a lab-on-a-chip microfluidic device for microdroplet generation and analysis with the mini-microscope and observed the formation of droplets under different flow conditions. Given its cost effectiveness, robust imaging and portability, the presented platform may be useful for a range of applications for real-time cellular imaging using lab-on-a-chip devices at low cost.

Rare complication of needleless mini-sling procedure: Case report.

PubMed

Karalar, Mustafa; Keles, Ibrahim; Unlu, Serdar; Sarici, Hasmet; Kose, Mesut; Ay, Cemil

2017-01-01

The mini-sling procedure is a widely used, minimally invasive treatment for stress urinary incontinence. While bladder perforation and stone formation over the mesh is not an expected complication of the mini-sling procedure, in this case, we report on the management of bladder calculi formed over the mesh, which was passed through the bladder while applying the mini-sling procedure, and was eventually removed using holmium laser. Performing cystoscopy in patients with irritative and obstructive symptoms after the sling procedure will help confirm bladder perforation, and an endoscopic approach using holmium laser is an effective treatment.

The Chemistry of a Mini

ERIC Educational Resources Information Center

Jones, C. E.

1972-01-01

Describes various parts of a mini car and their chemical composition. Useful information is included for science teachers to relate basic chemistry concepts and techniques with their application in automobile industry. (PS)

Mapping lightning in the sky with a mini array

NASA Astrophysics Data System (ADS)

Füllekrug, Martin; Liu, Zhongjian; Koh, Kuang; Mezentsev, Andrew; Pedeboy, Stéphane; Soula, Serge; Enno, Sven-Erik; Sugier, Jacqueline; Rycroft, Michael J.

2016-10-01

Mini arrays are commonly used for infrasonic and seismic studies. Here we report for the first time the detection and mapping of distant lightning discharges in the sky with a mini array. The array has a baseline to wavelength ratio ˜4.2·10-2 to record very low frequency electromagnetic waves from 2 to 18 kHz. It is found that the mini array detects ˜69 lightning pulses per second from cloud-to-ground and in-cloud discharges, even though the parent thunderstorms are ˜900-1100 km away and a rigorous selection criterion based on the quality of the wavefront across the array is used. In particular, lightning pulses that exhibit a clockwise phase progression are found at larger elevation angles in the sky as the result of a birefringent subionospheric wave propagation attributed to ordinary and extraordinary waves. These results imply that long range lightning detection networks might benefit from an exploration of the wave propagation conditions with mini arrays.

The mini-calorimeter of the AGILE satellite

NASA Astrophysics Data System (ADS)

Labanti, C.; Marisaldi, M.; Fuschino, F.; Galli, M.; Argan, A.; Bulgarelli, A.; Costa, E.; Di Cocco, G.; Gianotti, F.; Tavani, M.; Trifoglio, M.

2006-06-01

AGILE is a small space mission of the Italian Space Agency (ASI) devoted to astrophysics in the gamma-ray energy range 30 MeV - 50 GeV, and in the X-ray band 15 keV - 45 keV. The AGILE Payload is composed of three instruments: a gamma-ray imager based on a Tungsten-Silicon Tracker (ST), for observations in the gamma ray energy range 30 MeV - 50 GeV, a Silicon based X-ray detector, Super-Agile (SA), for imaging in the range 15 keV - 40 keV and a CsI(Tl) Mini-Calorimeter (MCAL) that detects gamma rays or particle energy deposits between 300 keV and 200 MeV. The payload is currently fully integrated and the satellite is expected to be launched in the second half of 2006. MCAL is composed of 30 CsI(Tl) scintillator detectors with the shape of a bar with photodiode readout at both ends, arranged in two orthogonal layers. MCAL can work both as a slave of the ST and as an independent gamma-ray detector for the detection of transients and Gamma Ray Bursts. In this paper a detailed description of MCAL is presented together with the first on ground calibration results.

Mini-TES Observations of Comanche Carbonate and Its Distribution

NASA Technical Reports Server (NTRS)

Ruff, Steven W.; Morris, Richard V.

2010-01-01

The discovery by the Spirit rover of outcrops rich in Mg-Fe carbonate [Morris et al., 2010] represents another manifestation of a diverse aqueous history in Gusev crater. In 2005, observations by the Moessbauer spectrometer (MB) on outcrops dubbed Comanche provided initial indication of Fe-Mg carbonate that was subsequently supported by analysis of elemental data from the Alpha Particle X-ray Spectrometer (APXS). The recognition of a carbonate component in thermal infrared spectra measured by the Miniature Thermal Emission Spectrometer (Mini-TES) was significantly delayed due to dust contamination of the instrument's optics. With the implementation of a viable dust correction, the Comanche spectra were revisited and presented clear and compelling evidence for a Mg-Fe carbonate component that could be as much as a third of the total mineral abundance. The data from all three instruments in combination are best matched by Mg-Fe carbonate with an abundance of 16-34 wt%. Mini-TES spectra were acquired for 12 targets at various locations on the Comanche (4-5 m long) and Comanche Spur (1-2 m long) outcrops, the latter being the location of the MB and APXS measurements. The two outcrops are spectrally comparable and share similar morphology and texture based on color images from the Panoramic Camera (Pancam). The highest quality Mini-TES spectrum comes from the larger Comanche outcrop on a target named Saupitty. Linear least squares modeling of the Saupitty spectrum employed a library of laboratory spectra tailored for consistency with the APXS and MB data and included spectra representing Martian dust, a slope spectrum to account for any temperature determination errors, and a blackbody spectrum to account for differences in spectral contrast between the laboratory and Mini-TES spectrum. Successful modeling of the Comanche Saupitty spectrum required one or more carbonate phases to obtain a good fit. Excluding all carbonates from the full starting library more than

Why are mini-implants lost: the value of the implantation technique!

PubMed

Romano, Fabio Lourenço; Consolaro, Alberto

2015-01-01

The use of mini-implants have made a major contribution to orthodontic treatment. Demand has aroused scientific curiosity about implant placement procedures and techniques. However, the reasons for instability have not yet been made totally clear. The aim of this article is to establish a relationship between implant placement technique and mini-implant success rates by means of examining the following hypotheses: 1) Sites of poor alveolar bone and little space between roots lead to inadequate implant placement; 2) Different sites require mini-implants of different sizes! Implant size should respect alveolar bone diameter; 3) Properly determining mini-implant placement site provides ease for implant placement and contributes to stability; 4) The more precise the lancing procedures, the better the implant placement technique; 5) Self-drilling does not mean higher pressures; 6) Knowing where implant placement should end decreases the risk of complications and mini-implant loss.

First Atmospheric Science Results from the Mars Exploration Rovers Mini-TES

NASA Technical Reports Server (NTRS)

Smith, Michael D.; Wolff, Michael J.; Lemmon, Mark T.; Spanovich, Nicole; Banfield, Don; Budney, Charles J.; Clancy, R. Todd; Ghosh, Amitabha; Landis, Geoffrey A.; Smith, Peter;

First Atmospheric Science Results from the Mars Exploration Rovers Mini-TES.

PubMed

Smith, Michael D; Wolff, Michael J; Lemmon, Mark T; Spanovich, Nicole; Banfield, Don; Budney, Charles J; Clancy, R Todd; Ghosh, Amitabha; Landis, Geoffrey A; Smith, Peter; Whitney, Barbara; Christensen, Philip R; Squyres, Steven W

2004-12-03

Thermal infrared spectra of the martian atmosphere taken by the Miniature Thermal Emission Spectrometer (Mini-TES) were used to determine the atmospheric temperatures in the planetary boundary layer and the column-integrated optical depth of aerosols. Mini-TES observations show the diurnal variation of the martian boundary layer thermal structure, including a near-surface superadiabatic layer during the afternoon and an inversion layer at night. Upward-looking Mini-TES observations show warm and cool parcels of air moving through the Mini-TES field of view on a time scale of 30 seconds. The retrieved dust optical depth shows a downward trend at both sites.

Residency Mini-fellowships in the PGY-5 Year: Is There Added Value?

PubMed

Shenoy-Bhangle, Anuradha S; Eisenberg, Ronald L; Fineberg, Tabitha; Slanetz, Priscilla J

2018-06-01

With the restructuring of radiology board certification, many residencies created PGY-5 "mini-fellowships," during which residents spend focused time pursuing advanced subspecialty training or developing nonclinical skills in leadership, health policy and health-care economics, education, quality improvement, informatics, research, or global health. We surveyed graduates of an academic diagnostic radiology residency to assess the relative value and impact of PGY-5 mini-fellowships on career satisfaction and success. From 2012 to 2016, 39 radiology residents at our institution were offered the opportunity to pursue a 3- to 6-month mini-fellowship during the PGY-5 year. Thirty of 39 radiology residents (77%) participated, whereas 9 of 39 (23%) opted out. Of 39 residents, 13 completed two clinical mini-fellowships, 3 completed research mini-fellowships only, and 14 completed one nonclinical and one clinical mini-fellowship. Through SurveyMonkey, 23 of 39 residents (59%) responded to a questionnaire that collected basic demographic information and asked respondents about the value of this experience as it relates to fellowship choice and career using a five-point Likert scale. Of 23 respondents (14 male, 8 female,1 not specified), 78.3% practice in an academic university-based setting, with 8.7% in a community-based hospital practice, 4.3% in the veterans system, and 4.3% in a private practice setting. Of 23 respondents, the most popular clinical mini-fellowships were magnetic resonance imaging (31.6%), neuroradiology (21.1%), and interventional radiology (15.8%). For nonclinical mini-fellowships, the most popular were research (10.5%), education (10.5%), global health (5.3%), and healthcare economics (5.3%). Of 23 respondents who did mini-fellowships, 95% felt that the mini-fellowship prepared them well for their career, 85% felt it gave them the necessary skills to succeed, 85% cited that it gave them additional skills beyond their peers, and 40% felt it helped them

Internal Structure of Mini-CEX Scores for Internal Medicine Residents: Factor Analysis and Generalizability

ERIC Educational Resources Information Center

Cook, David A.; Beckman, Thomas J.; Mandrekar, Jayawant N.; Pankratz, V. Shane

2010-01-01

The mini-CEX is widely used to rate directly observed resident-patient encounters. Although several studies have explored the reliability of mini-CEX scores, the dimensionality of mini-CEX scores is incompletely understood. Objective: Explore the dimensionality of mini-CEX scores through factor analysis and generalizability analysis. Design:…

Mini-Digest of Education Statistics, 2008. NCES 2009-021

ERIC Educational Resources Information Center

Snyder, Thomas D.

2009-01-01

This publication is the 14th edition of the "Mini-Digest of Education Statistics," a pocket-sized compilation of statistical information covering the broad field of American education from kindergarten through graduate school. The "Mini-Digest" is designed as an easy reference for materials found in much greater detail in the…

Fibrous mini-collagens in hydra nematocysts.

PubMed

Holstein, T W; Benoit, M; Herder, G V; David, C N; Wanner, G; Gaub, H E

1994-07-15

Nematocysts (cnidocysts) are exocytotic organelles found in all cnidarians. Here, atomic force microscopy and field emission scanning electron microscopy reveal the structure of the nematocyst capsule wall. The outer wall consists of globular proteins of unknown function. The inner wall consists of bundles of collagen-like fibrils having a spacing of 50 to 100 nanometers and cross-striations at intervals of 32 nanometers. The fibrils consist of polymers of "mini-collagens," which are abundant in the nematocysts of Hydra. The distinct pattern of mini-collagen fibers in the inner wall can provide the tensile strength necessary to withstand the high osmotic pressure (15 megapascals) in the capsules.

Replacing a failed mini-implant with a miniplate to prevent interruption during orthodontic treatment.

PubMed

Lee, Jin-Hwa; Choo, Hyeran; Kim, Seong-Hun; Chung, Kyu-Rhim; Giannuzzi, Lucille A; Ngan, Peter

2011-06-01

When mini-implants fail during orthodontic treatment, there is a need to have a backup plan to either replace the failed implant in the adjacent interradicular area or wait for the bone to heal before replacing the mini-implant. We propose a novel way to overcome this problem by replacement with a miniplate so as not to interrupt treatment or prolong treatment time. The indications, advantages, efficacy, and procedures for switching from a mini-implant to a miniplate are discussed. Two patients who required replacement of failed mini-implants are presented. In the first patient, because of the proximity of the buccal vestibule to the mini-implant, it was decided to replace the failed mini-implant by an I-shaped C-tube miniplate. In the second patient, radiolucencies were found around the failed mini-implants, making the adjacent alveolar bone unavailable for immediate placement of another mini-implant. In addition, the maxillary sinus pneumatization was expanded deeply into the interradicular spaces; this further mandated an alternative placement site. One failed mini-implant was examined under a scanning electron microscope for bone attachment. Treatment was completed in both patients after replacement with miniplates without interrupting the treatment mechanics or prolonging the treatments. Examination under the scanning electron microscope showed partial bone growth into the coating pores and titanium substrate interface even after thorough cleaning and sterilization. Replacement with a miniplate is a viable solution for failed mini-implants during orthodontic treatment. The results from microscopic evaluation of the failed mini-implant suggest that stringent guidelines are needed for recycling used mini-implants. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

Photoelectrochemical and theoretical investigations of spinel type ferrites (MxFe3-xO4) for water splitting: a mini-review

NASA Astrophysics Data System (ADS)

Taffa, Dereje H.; Dillert, Ralf; Ulpe, Anna C.; Bauerfeind, Katharina C. L.; Bredow, Thomas; Bahnemann, Detlef W.; Wark, Michael

2017-01-01

Solar-assisted water splitting using photoelectrochemical cells (PECs) is one of the promising pathways for the production of hydrogen for renewable energy storage. The nature of the semiconductor material is the primary factor that controls the overall energy conversion efficiency. Finding semiconductor materials with appropriate semiconducting properties (stability, efficient charge separation and transport, abundant, visible light absorption) is still a challenge for developing materials for solar water splitting. Owing to the suitable bandgap for visible light harvesting and the abundance of iron-based oxide semiconductors, they are promising candidates for PECs and have received much research attention. Spinel ferrites are subclasses of iron oxides derived from the classical magnetite (FeIIFe2IIIO4) in which the FeII is replaced by one (some cases two) additional divalent metals. They are generally denoted as MxFe3-xO4 (M=Ca, Mg, Zn, Co, Ni, Mn, and so on) and mostly crystallize in spinel or inverse spinel structures. In this mini review, we present the current state of research in spinel ferrites as photoelectrode materials for PECs application. Strategies to improve energy conversion efficiency (nanostructuring, surface modification, and heterostructuring) will be presented. Furthermore, theoretical findings related to the electronic structure, bandgap, and magnetic properties will be presented and compared with experimental results.

Fast-Flowering Mini-Maize: Seed to Seed in 60 Days

PubMed Central

McCaw, Morgan E.; Wallace, Jason G.; Albert, Patrice S.; Buckler, Edward S.; Birchler, James A.

2016-01-01

Two lines of Zea mays were developed as a short-generation model for maize. The Fast-Flowering Mini-Maize (FFMM) lines A and B are robust inbred lines with a significantly shorter generation time, much smaller stature, and better greenhouse adaptation than traditional maize varieties. Five generations a year are typical. FFMM is the result of a modified double-cross hybrid between four fast-flowering lines: Neuffer’s Early ACR (full color), Alexander’s Early Early Synthetic, Tom Thumb Popcorn, and Gaspe Flint, followed by selection for early flowering and desirable morphology throughout an 11-generation selfing regime. Lines A and B were derived from different progeny of the initial hybrid, and crosses between Mini-Maize A and B exhibit heterosis. The ancestry of each genomic region of Mini-Maize A and B was inferred from the four founder populations using genotyping by sequencing. Other genetic and genomic tools for these lines include karyotypes for both lines A and B, kernel genetic markers y1 (white endosperm) and R1-scm2 (purple endosperm and embryo) introgressed into Mini-Maize A, and ∼24× whole-genome resequencing data for Mini-Maize A. PMID:27440866

Gender and Self-Employment: The Role of Mini-Companies

ERIC Educational Resources Information Center

Johansen, Vegard

2016-01-01

Purpose: The purpose of this paper is to evaluate to what degree participation in mini-companies impact young women and men with regard to the perceived desirability and perceived feasibility of self-employment. The Company Programme (CP) is the largest mini-company scheme in European secondary school. Design/methodology/approach: The data derived…

From ozone mini-holes and mini-highs towards extreme value theory: New insights from extreme events and non-stationarity

NASA Astrophysics Data System (ADS)

Rieder, H. E.; Staehelin, J.; Maeder, J. A.; Ribatet, M.; Stübi, R.; Weihs, P.; Holawe, F.; Peter, T.; Davison, A. C.

2009-04-01

"extremes concept" provides new information on the data distribution and variability within the Arosa record as well as on the influence of ELOs and EHOs on the long-term trends of the ozone time series. References: Bojkov, R. D., and Balis, D.S.: Characteristics of episodes with extremely low ozone values in the northern middle latitudes 1975-2000, Ann. Geophys., 19, 797-807, 2001. Coles, S.: An Introduction to Statistical Modeling of Extreme Values, Springer Series in Statistics, ISBN:1852334592, Springer, Berlin, 2001. Pickands, J.: Statistical inference using extreme order statistics, Ann. Stat., 3, 1, 119-131, 1975. Ribatet, M.: POT: Modelling peaks over a threshold, R News, 7, 34-36, 2007. Rieder, H.E., Staehelin, J., Maeder, J.A., Stübi, R., Weihs, P., Holawe, F., and M. Ribatet: From ozone mini holes and mini highs towards extreme value theory: New insights from extreme events and non stationarity, submitted to J. Geophys. Res., 2009. Staehelin, J., Kegel, R., and Harris, N. R.: Trend analysis of the homogenized total ozone series of Arosa (Switzerland), 1929-1996, J. Geophys. Res., 103(D7), 8389-8400, doi:10.1029/97JD03650, 1998a. Staehelin, J., Renaud, A., Bader, J., McPeters, R., Viatte, P., Hoegger, B., Bugnion, V., Giroud, M., and Schill, H.: Total ozone series at Arosa (Switzerland): Homogenization and data comparison, J. Geophys. Res., 103(D5), 5827-5842, doi:10.1029/97JD02402, 1998b.

Time domain modal identification/estimation of the mini-mast testbed

NASA Technical Reports Server (NTRS)

Roemer, Michael J.; Mook, D. Joseph

1991-01-01

The Mini-Mast is a 20 meter long 3-dimensional, deployable/retractable truss structure designed to imitate future trusses in space. Presented here are results from a robust (with respect to measurement noise sensitivity), time domain, modal identification technique for identifying the modal properties of the Mini-Mast structure even in the face of noisy environments. Three testing/analysis procedures are considered: sinusoidal excitation near resonant frequencies of the Mini-Mast, frequency response function averaging of several modal tests, and random input excitation with a free response period.

Do dual-thread orthodontic mini-implants improve bone/tissue mechanical retention?

PubMed

Lin, Yang-Sung; Chang, Yau-Zen; Yu, Jian-Hong; Lin, Chun-Li

2014-12-01

The aim of this study was to understand whether the pitch relationship between micro and macro thread designs with a parametrical relationship in a dual-thread mini-implant can improve primary stability. Three types of mini-implants consisting of single-thread (ST) (0.75 mm pitch in whole length), dual-thread A (DTA) with double-start 0.375 mm pitch, and dual-thread B (DTB) with single-start 0.2 mm pitch in upper 2-mm micro thread region for performing insertion and pull-out testing. Histomorphometric analysis was performed in these specimens in evaluating peri-implant bone defects using a non-contact vision measuring system. The maximum inserted torque (Tmax) in type DTA was found to be the smallest significantly, but corresponding values found no significant difference between ST and DTB. The largest pull-out strength (Fmax) in the DTA mini-implant was found significantly greater than that for the ST mini-implant regardless of implant insertion orientation. Mini-implant engaged the cortical bone well as observed in ST and DTA types. Dual-thread mini-implant with correct micro thread pitch (parametrical relationship with macro thread pitch) in the cortical bone region can improve primary stability and enhanced mechanical retention.

Flexible Ureterorenoscopy versus Mini-Percutaneous Nephrolithotomy for the Treatment of Renal Stones.

PubMed

Ergin, Giray; Kirac, Mustafa; Kopru, Burak; Ebiloglu, Turgay; Biri, Hasan

2018-04-22

To compare the pain status and stone free rates of flexible ureterorenoscopy (F-URS) versus mini-percutaneousnephrolithotomy (mini-PNL) for the treatment of 1-to 2-cm renal stones. This study was retrospectively designed with match paired method. Between January 2013 and December 2016, 387 patients underwent stone surgery for renal stones, 45 patients underwent FURS and 45 patients underwent mini-PNL. 90 patients were divided into two groups according to the surgical procedures. Group 1 patients underwent F-URS, and Group 2 patients underwent mini-PNL. During the intraoperative andpostoperative periods, pain management for all patients was standardized. Pain scores were determined using a visual analogue scale (VAS) completed at 2, 6, 12 and 24 hours postoperatively. The stone free status, hemoglobin levels, fluoroscopy time (FT), operation time (OT), hospitalization time (HT), return to work time (RWT), and complications were noted for each patient. Of all patients, the mean age was 41.1 ± 12.1 years and the mean stone size was 13.9 ± 2.9 mm. The VAS scores were significantly higher in the mini-PNL group at 2, 6, 12 and 24 hours (P < .05). The stone-free status and complication rates were similar between the two groups (P > .05); however, the hemoglobin decreases and the fluoroscopy, operation, hospitalization and return to work times were higher in the mini-PNL group than in the F-URS group (P < .05). F-URS is less painful than mini-PNL for the treatment of 1- to 2-cm renal stones. However, the stone free rate is similar between the two procedures while mini-PNL is superior in terms of fluoroscopy, operation, hospitalization and return to work duration. We think that F-URS is more comfortable and less painful than mini-PNL and achieves a similar stone free rate for the treatment of 1- to 2-cm renal stones.

The Galactic Centre Mini-Spiral with CARMA

NASA Technical Reports Server (NTRS)

Kunneriath, D.; Eckart, A.; Vogel, S. N.; Teuben, P.; Muzic, K.; Schodel. R.; Garcia-Marin, M.; Moultaka, J.; Staguhn, J.; Straubmeier, C.;

Macromolecular crystallography beamline X25 at the NSLS

PubMed Central

Héroux, Annie; Allaire, Marc; Buono, Richard; Cowan, Matthew L.; Dvorak, Joseph; Flaks, Leon; LaMarra, Steven; Myers, Stuart F.; Orville, Allen M.; Robinson, Howard H.; Roessler, Christian G.; Schneider, Dieter K.; Shea-McCarthy, Grace; Skinner, John M.; Skinner, Michael; Soares, Alexei S.; Sweet, Robert M.; Berman, Lonny E.

2014-01-01

Beamline X25 at the NSLS is one of the five beamlines dedicated to macromolecular crystallography operated by the Brookhaven National Laboratory Macromolecular Crystallography Research Resource group. This mini-gap insertion-device beamline has seen constant upgrades for the last seven years in order to achieve mini-beam capability down to 20 µm × 20 µm. All major components beginning with the radiation source, and continuing along the beamline and its experimental hutch, have changed to produce a state-of-the-art facility for the scientific community. PMID:24763654

Performance analysis of mini-propellers based on FlightGear

NASA Astrophysics Data System (ADS)

Vogeltanz, Tomáš

2016-06-01

This paper presents a performance analysis of three mini-propellers based on the FlightGear flight simulator. Although a basic propeller analysis has to be performed before the use of FlightGear, for a complex and more practical performance analysis, it is advantageous to use a propeller model in cooperation with a particular aircraft model. This approach may determine whether the propeller has sufficient quality in respect of aircraft requirements. In the first section, the software used for the analysis is illustrated. Then, the parameters of the analyzed mini-propellers and the tested UAV are described. Finally, the main section shows and discusses the results of the performance analysis of the mini-propellers.

Optimal area of lateral mass mini-screws implanted in plated cervical laminoplasty: a radiography anatomy study.

PubMed

Chen, Hua; Li, Huibo; Deng, Yuxiao; Rong, Xin; Gong, Quan; Li, Tao; Song, Yueming; Liu, Hao

2017-04-01

Lateral mass mini-screws used in plated cervical laminoplasty might penetrate into facet joints. The objective is to observe this complication incidence and to identify the optimal areas for 5- and 7-mm-long mini-screws to implant on lateral mass. 47 patients who underwent plated cervical laminoplasty were included. The optimal area for mini-screws implanting was set according to pre-operative 3D CT reconstruction data. Then, each posterior-lateral mass surface was divided into three regions: 7-mm region, 5-mm region, and dangerous area. The mini-screw implanted region was recorded. Post-operative CT images were used to identify whether the mini-screws penetrated into facet joints. 235 mini-plates and 470 lateral mass mini-screws were used in the study. 117 (24.9%) mini-screws penetrated 88 (37.4%) facet joints. The 5-mm-long mini-screw optimal area occupied the upper 72, 65, 65, 64, and 65 % area of the posterior-lateral mass surface for C3-7, while the 7-mm-long mini-screw optimal area encompassed the upper 54, 39, 40, 33, and 32 %. Only 7-mm-long mini-screws were used to fix the plate to the lateral mass. 4 of 240 mini-screws in 7-mm region, 67 of the 179 mini-screws in 5-mm region, and 46 of the 51 mini-screws in dangerous region penetrated into the facet joint. The differences in the rate of facet joint penetration related to region were statistically significant (P < 0.001). The facet joint destruction by mini-screws was not a rare complication in plated cervical laminoplasty. The optimal areas we proposed may help guide the mini-screw implantation positions.

Design and Reproducibility of a Mini-Survey to Evaluate the Quality of Food Intake (Mini-ECCA) in a Mexican Population

PubMed Central

González-Gómez, Montserrat; Orozco-Gutiérrez, Jaime Fernando; Prado-Arriaga, Ruth Jackelyne; Márquez-Sandoval, Fabiola; Altamirano-Martínez, Martha Betzaida

2018-01-01

Evaluating food intake quality may contribute to the development of nutrition programs. In Mexico, there are no screening tools that can be administered quickly for the evaluation of this variable. The aim was to determine the reproducibility of a mini-survey designed to evaluate the quality of food intake (Mini-ECCA) in a Mexican population. Mini-ECCA consists of 12 questions that are based on Mexican and international recommendations for food and non-alcoholic beverage intake, with the support of photographs for food quantity estimation. Each question scores as 0 (unhealthy) or 1 (healthy), and the final score undergoes a classification procedure. Through the framework of a nutritional study, 152 employees of the municipal water company in Guadalajara, Mexico (April–August 2016), were invited to participate. The survey was administered in two rounds (test and retest) with a 15-day interval between them. We calculated the Spearman correlation coefficient, the intra-class correlation coefficient (ICC), and weighted kappa for score classification agreement (SPSS versus 14 p < 0.05 was considered statistically significant). The survey obtained a “good” reproducibility (ρ = 0.713, p < 0.001), and an excellent concordance (ICC = 0.841 Confidence Interval 95% 0.779, 0.885). It can thus be said that the Mini-ECCA displayed acceptable reproducibility and is suitable for the purpose of dietary assessment and guidance. PMID:29690618

Design and Reproducibility of a Mini-Survey to Evaluate the Quality of Food Intake (Mini-ECCA) in a Mexican Population.

PubMed

Bernal-Orozco, María Fernanda; Badillo-Camacho, Nayeli; Macedo-Ojeda, Gabriela; González-Gómez, Montserrat; Orozco-Gutiérrez, Jaime Fernando; Prado-Arriaga, Ruth Jackelyne; Márquez-Sandoval, Fabiola; Altamirano-Martínez, Martha Betzaida; Vizmanos, Barbara

2018-04-23

Evaluating food intake quality may contribute to the development of nutrition programs. In Mexico, there are no screening tools that can be administered quickly for the evaluation of this variable. The aim was to determine the reproducibility of a mini-survey designed to evaluate the quality of food intake (Mini-ECCA) in a Mexican population. Mini-ECCA consists of 12 questions that are based on Mexican and international recommendations for food and non-alcoholic beverage intake, with the support of photographs for food quantity estimation. Each question scores as 0 (unhealthy) or 1 (healthy), and the final score undergoes a classification procedure. Through the framework of a nutritional study, 152 employees of the municipal water company in Guadalajara, Mexico (April⁻August 2016), were invited to participate. The survey was administered in two rounds (test and retest) with a 15-day interval between them. We calculated the Spearman correlation coefficient, the intra-class correlation coefficient (ICC), and weighted kappa for score classification agreement (SPSS versus 14 p < 0.05 was considered statistically significant). The survey obtained a “good” reproducibility (ρ = 0.713, p < 0.001), and an excellent concordance (ICC = 0.841 Confidence Interval 95% 0.779, 0.885). It can thus be said that the Mini-ECCA displayed acceptable reproducibility and is suitable for the purpose of dietary assessment and guidance.

Mini-Sniffer III on Lakebed with Ground Support Crew

NASA Technical Reports Server (NTRS)

1976-01-01

The third version of the Mini-Sniffer remotely-piloted research vehicle on Rogers Dry Lake, adjacent to NASA's Dryden Flight Research Center, Edwards, California. The futuristic-looking ground crew are in white, self-contained suits, because the engine on this third version of the Mini-Sniffer was powered by hydrazine, which is a very hazardous material. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the

Next Generation Fast Neutron Detector for Space Exploration (Mini-FND)

NASA Astrophysics Data System (ADS)

Hassler, D. M.; Ehresmann, B.

2018-02-01

SwRI has developed a miniature Fast Neutron Detector (mini-FND), for use in the Deep Space Gateway, to characterize the neutron albedo radiation. Mini-FND will provide coverage of the biologically relevant neutrons at energies of 500 keV and greater.

Design and construction of the Mini-Calorimeter of the AGILE satellite

NASA Astrophysics Data System (ADS)

Labanti, C.; Marisaldi, M.; Fuschino, F.; Galli, M.; Argan, A.; Bulgarelli, A.; Di Cocco, G.; Gianotti, F.; Tavani, M.; Trifoglio, M.

2009-01-01

AGILE is a small space mission of the Italian Space Agency (ASI) devoted to gamma-ray and hard-X astrophysics, successfully launched on April 23, 2007. The AGILE Payload is composed of three instruments: a gamma-ray imager based on a tungsten-silicon tracker (ST), for observations in the gamma ray energy range 30 MeV-50 GeV, a Silicon based X-ray detector, SuperAGILE (SA), for imaging in the range 18-60 keV and a CsI(Tl) Mini-Calorimeter (MCAL) that detects gamma rays or charged particles energy loss in the range 300 keV-100 MeV. MCAL is composed of 30 CsI(Tl) scintillator bars with photodiode readout at both ends, arranged in two orthogonal layers. MCAL can work both as a slave of the ST and as an independent gamma-ray detector for transients and gamma-ray bursts detection. In this paper a detailed description of MCAL is presented together with its performance.

Cryopreservation of boar semen in mini- and maxi-straws.

PubMed

Bwanga, C O; de Braganca, M M; Einarsson, S; Rodriguez-Martinez, H

1990-10-01

Split ejaculates from four boars were frozen with a programmable freezing machine, in mini- (0.25 ml) and maxi- (5 ml) plastic straws with an extender at either acidic (6.3) or alkaline (7.4) pH. Glycerol (3%) was used as cryoprotectant. The freezing of the semen was monitored by way of thermocouples placed in the straws. Post-thaw motility and acrosome integrity were evaluated; the latter using phase contrast microscopy, eosin-nigrosin stain and electron microscopy. Post-thaw sperm motility was significantly higher when semen was frozen in mini-straws than in maxi-straws. For the mini-straws, the motility was better when semen was exposed to an acidic environment during freezing, but this beneficial effect of the low extracellular pH was not evident when maxi-straws were thawed. The motility of the spermatozoa diminished significantly during the thermoresistance test (0 h and 2 h time) at 37 degrees C in a similar way for both straws and extracellular pH's. The freezing procedure, no matter the extracellular pH, did not cause major acrosomal damages, but significantly more normal apical ridges were present in the mini-straws than in the maxi-straws. This in vitro evaluation indicated that the freezing method employed was better for mini- than for maxi-straws since the freezing of the 5 ml volumes was not homogeneous, due to the large section area between the surface and the core of the straw.

A mini-microscope for in situ monitoring of cells†‡

PubMed Central

Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R.; Hamilton, Geraldine A.; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E.

2013-01-01

A mini-microscope was developed for in situ monitoring of cells by modifying off-the-shelf components of a commercial webcam. The mini-microscope consists of a CMOS imaging module, a small plastic lens and a white LED illumination source. The CMOS imaging module was connected to a laptop computer through a USB port for image acquisition and analysis. Due to its compact size, 8 × 10 × 9 cm, the present microscope is portable and can easily fit inside a conventional incubator, and enables real-time monitoring of cellular behaviour. Moreover, the mini-microscope can be used for imaging cells in conventional cell culture flasks, such as Petri dishes and multi-well plates. To demonstrate the operation of the mini-microscope, we monitored the cellular migration of mouse 3T3 fibroblasts in a scratch assay in medium containing three different concentrations of fetal bovine serum (5, 10, and 20%) and demonstrated differential responses depending on serum levels. In addition, we seeded embryonic stem cells inside poly(ethylene glycol) microwells and monitored the formation of stem cell aggregates in real time using the mini-microscope. Furthermore, we also combined a lab-on-a-chip microfluidic device for microdroplet generation and analysis with the mini-microscope and observed the formation of droplets under different flow conditions. Given its cost effectiveness, robust imaging and portability, the presented platform may be useful for a range of applications for real-time cellular imaging using lab-on-a-chip devices at low cost. PMID:22911426

Contrasting influences of Drosophila white/mini-white on ethanol sensitivity in two different behavioral assays.

PubMed

Chan, Robin F; Lewellyn, Lara; DeLoyht, Jacqueline M; Sennett, Kristyn; Coffman, Scarlett; Hewitt, Matthew; Bettinger, Jill C; Warrick, John M; Grotewiel, Mike

2014-06-01

The fruit fly Drosophila melanogaster has been used extensively to investigate genetic mechanisms of ethanol (EtOH)-related behaviors. Many past studies in flies, including studies from our laboratory, have manipulated gene expression using transposons carrying the genetic-phenotypic marker mini-white(mini-w), a derivative of the endogenous gene white(w). Whether the mini-w transgenic marker or the endogenous w gene influences behavioral responses to acute EtOH exposure in flies has not been systematically investigated. We manipulated mini-w and w expression via (i) transposons marked with mini-w, (ii) RNAi against mini-w and w, and (iii) a null allele of w. We assessed EtOH sensitivity and tolerance using a previously described eRING assay (based on climbing in the presence of EtOH) and an assay based on EtOH-induced sedation. In eRING assays, EtOH-induced impairment of climbing correlated inversely with expression of the mini-w marker from a series of transposon insertions. Additionally, flies harboring a null allele of w or flies with RNAi-mediated knockdown of mini-w were significantly more sensitive to EtOH in eRING assays than controls expressing endogenous w or the mini-w marker. In contrast, EtOH sensitivity and rapid tolerance measured in the EtOH sedation assay were not affected by decreased expression of mini-w or endogenous w in flies. EtOH sensitivity measured in the eRING assay is noticeably influenced by w and mini-w, making eRING problematic for studies on EtOH-related behavior in Drosophila using transgenes marked with mini-w. In contrast, the EtOH sensitivity assay described here is a suitable behavioral paradigm for studies on EtOH sensitivity and rapid tolerance in Drosophila including those that use widely available transgenes marked with mini-w. Copyright © 2014 by the Research Society on Alcoholism.

Pool boiling on surfaces with mini-fins and micro-cavities

NASA Astrophysics Data System (ADS)

Pastuszko, Robert; Piasecka, Magdalena

2012-11-01

The experimental studies presented here focused on pool boiling heat transfer on mini-fin arrays, mini-fins with perforated covering and surfaces with micro-cavities. The experiments were carried out for water and fluorinert FC-72 at atmospheric pressure. Mini-fins of 0.5 and 1 mm in height were uniformly spaced on the base surface. The copper foil with holes of 0.1 mm in diameter (pitch 0.2/0.4 mm), sintered with the fin tips, formed a system of connected perpendicular and horizontal tunnels. The micro-cavities were obtained through spark erosion. The maximal depth of the craters of these cavities was 15 - 30 μm and depended on the parameters of the branding-pen settings. At medium and small heat fluxes, structures with mini-fins showed the best boiling heat transfer performance both for water and FC-72. At medium and high heat fluxes (above 70 kW/m2 for water and 25 kW/m2 for FC-72), surfaces with mini-fins without porous covering and micro-cavities produced the highest heat transfer coefficients. The surfaces obtained with spark erosion require a proper selection of geometrical parameters for particular liquids - smaller diameters of cavities are suitable for liquids with lower surface tension (FC-72).

Mini-TES Observations of Comanche Carbonate and its Distribution

NASA Astrophysics Data System (ADS)

Ruff, S. W.; Morris, R. V.

2010-12-01

The discovery by the Spirit rover of outcrops rich in Mg-Fe carbonate [Morris et al., 2010] represents another manifestation of a diverse aqueous history in Gusev crater. In 2005, observations by the Mössbauer spectrometer (MB) on outcrops dubbed Comanche provided initial indication of Fe-Mg carbonate that was subsequently supported by analysis of elemental data from the Alpha Particle X-ray Spectrometer (APXS). The recognition of a carbonate component in thermal infrared spectra measured by the Miniature Thermal Emission Spectrometer (Mini-TES) was significantly delayed due to dust contamination of the instrument’s optics. With the implementation of a viable dust correction, the Comanche spectra were revisited and presented clear and compelling evidence for a Mg-Fe carbonate component that could be as much as a third of the total mineral abundance. The data from all three instruments in combination are best matched by Mg-Fe carbonate with an abundance of 16-34 wt%. Mini-TES spectra were acquired for 12 targets at various locations on the Comanche (4-5 m long) and Comanche Spur (1-2 m long) outcrops, the latter being the location of the MB and APXS measurements. The two outcrops are spectrally comparable and share similar morphology and texture based on color images from the Panoramic Camera (Pancam). The highest quality Mini-TES spectrum comes from the larger Comanche outcrop on a target named Saupitty. Linear least squares modeling of the Saupitty spectrum employed a library of laboratory spectra tailored for consistency with the APXS and MB data and included spectra representing Martian dust, a “slope” spectrum to account for any temperature determination errors, and a blackbody spectrum to account for differences in spectral contrast between the laboratory and Mini-TES spectra. Successful modeling of the Comanche Saupitty spectrum required one or more carbonate phases to obtain a good fit. Excluding all carbonates from the full starting library more than

A DNA Mini-Barcoding System for Authentication of Processed Fish Products.

PubMed

Shokralla, Shadi; Hellberg, Rosalee S; Handy, Sara M; King, Ian; Hajibabaei, Mehrdad

2015-10-30

Species substitution is a form of seafood fraud for the purpose of economic gain. DNA barcoding utilizes species-specific DNA sequence information for specimen identification. Previous work has established the usability of short DNA sequences-mini-barcodes-for identification of specimens harboring degraded DNA. This study aims at establishing a DNA mini-barcoding system for all fish species commonly used in processed fish products in North America. Six mini-barcode primer pairs targeting short (127-314 bp) fragments of the cytochrome c oxidase I (CO1) DNA barcode region were developed by examining over 8,000 DNA barcodes from species in the U.S. Food and Drug Administration (FDA) Seafood List. The mini-barcode primer pairs were then tested against 44 processed fish products representing a range of species and product types. Of the 44 products, 41 (93.2%) could be identified at the species or genus level. The greatest mini-barcoding success rate found with an individual primer pair was 88.6% compared to 20.5% success rate achieved by the full-length DNA barcode primers. Overall, this study presents a mini-barcoding system that can be used to identify a wide range of fish species in commercial products and may be utilized in high throughput DNA sequencing for authentication of heavily processed fish products.

The Mini-Economy: Integrating Economics into the Elementary Curriculum.

ERIC Educational Resources Information Center

Indiana State Dept. of Education, Indianapolis.

The focus of this guide is to simulate real world economic activity in the classroom by using a form of economics instruction called a " mini-economy." In a mini-economy, students earn play money in a variety of ways and spend it at a class store or class auction. Students apply for classroom jobs, run businesses, pay taxes, buy rental properties,…

Implementing the undergraduate mini-CEX: a tailored approach at Southampton University.

PubMed

Hill, Faith; Kendall, Kathleen; Galbraith, Kevin; Crossley, Jim

2009-04-01

The mini-clinical evaluation exercise (mini-CEX) is widely used in the UK to assess clinical competence, but there is little evidence regarding its implementation in the undergraduate setting. This study aimed to estimate the validity and reliability of the undergraduate mini-CEX and discuss the challenges involved in its implementation. A total of 3499 mini-CEX forms were completed. Validity was assessed by estimating associations between mini-CEX score and a number of external variables, examining the internal structure of the instrument, checking competency domain response rates and profiles against expectations, and by qualitative evaluation of stakeholder interviews. Reliability was evaluated by overall reliability coefficient (R), estimation of the standard error of measurement (SEM), and from stakeholders' perceptions. Variance component analysis examined the contribution of relevant factors to students' scores. Validity was threatened by various confounding variables, including: examiner status; case complexity; attachment specialty; patient gender, and case focus. Factor analysis suggested that competency domains reflect a single latent variable. Maximum reliability can be achieved by aggregating scores over 15 encounters (R = 0.73; 95% confidence interval [CI] +/- 0.28 based on a 6-point assessment scale). Examiner stringency contributed 29% of score variation and student attachment aptitude 13%. Stakeholder interviews revealed staff development needs but the majority perceived the mini-CEX as more reliable and valid than the previous long case. The mini-CEX has good overall utility for assessing aspects of the clinical encounter in an undergraduate setting. Strengths include fidelity, wide sampling, perceived validity, and formative observation and feedback. Reliability is limited by variable examiner stringency, and validity by confounding variables, but these should be viewed within the context of overall assessment strategies.

High-flying Mini-Sniffer RPV - Mars bound

NASA Technical Reports Server (NTRS)

Reed, R. D.

1978-01-01

The Mini-Sniffer is a small unmanned survey aircraft developed by NASA to conduct turbulence and atmospheric pollution measurements from ground level to an altitude of 90,000 ft. Carrying a 25-lb air sampling apparatus, the Mini-Sniffer typically cruises for one hour at 70,000 ft before being remotely piloted back to earth. A hydrazine monopropellant engine powers the craft, while a PCM telemetering system and a radar transponder provide control functions. Development of a high-performance low-Reynolds-number airfoil could make the research craft suitable for a low-altitude terrain-following mission on Mars.

The Mini-Social Phobia Inventory: psychometric properties in an adolescent general population sample.

PubMed

Ranta, Klaus; Kaltiala-Heino, Riittakerttu; Rantanen, Päivi; Marttunen, Mauri

2012-07-01

Onset of social phobia (SP) typically occurs in adolescence. Short screening instruments for its assessment are needed for use in primary health and school settings. The 3-item Mini-Social Phobia Inventory (SPIN) has demonstrated effectiveness in screening for generalized SP (GSP) in adults. This study examined the psychometrics of the Mini-SPIN in an adolescent general population sample. Three hundred fifty adolescents aged 12 to 17 years were clinically interviewed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version for identification of SP and other Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I disorders, blind to their Mini-SPIN status. Associations between SP; subclinical SP; other anxiety, depressive, and disruptive disorders; and Mini-SPIN scores were examined, and diagnostic efficiency statistics were calculated. The association between Mini-SPIN scores and the generalized subtype of SP was also examined. As in adults, the Mini-SPIN items differentiated subjects with SP from those without. A score of 6 points or greater was found optimal in predicting SP with a sensitivity of 86%, specificity of 84%, and positive and negative predictive values of 26% and 99%. The Mini-SPIN also possessed discriminative validity, as scores were higher for adolescents with SP than they were for those with depressive, disruptive, and other anxiety disorders. The Mini-SPIN was also able to differentiate adolescents with GSP from the rest of the sample. The Mini-SPIN has good psychometrics for screening SP in adolescents from general population and may have value in screening for GSP. Copyright © 2012 Elsevier Inc. All rights reserved.

MiniCOR: A miniature coronagraph for an interplanetary CUBESAT

NASA Astrophysics Data System (ADS)

Vourlidas, A.; Korendyke, C.; Liewer, P. C.; Cutler, J.; Howard, R.; Plunkett, S. P.; Thernisien, A. F.

2015-12-01

Coronagraphs occupy a unique place in Heliophysics, critical to both NAA and NOAA programs. They are the primary means for the study of the extended solar coorna and its short/long term activity. In addition coronagraphs are the only instrument that can image coronal mass ejections (CMEs) leaving the Sun and provide ciritical information for space weather forecasting. We descirbe a low cost miniaturzied CubeSat coronagraph, MiniCOR, designed to operate in deep space which will returndata with higher cadence and sensitivity than that from the SOHO/LASCO coronagraphs. MiniCOR is a six unit (6U) science craft with a tightly integrated, single instrument interplanetary flight system optiized for science. MiniCOR fully exploits recent technology advance in CubeSat technology and active pixel sensors. With a factor of 2.9 improvement in light gathering power over SOHO and quasi-continuous data collection, MiniCOR can observe the slow solar wind, CMEs and shocks with sufficient signal-to-noise ratio (SNR) to open new windows on our understanding of the inner Heliosphere. An operating Minic'OR would prvide coornagraphic observations in support of the upcoming Solar Probe Plus (SPP) and Solar Orbiter (SO) missions.

A cost-effective fluorescence mini-microscope for biomedical applications.

PubMed

Zhang, Yu Shrike; Ribas, João; Nadhman, Akhtar; Aleman, Julio; Selimović, Šeila; Lesher-Perez, Sasha Cai; Wang, Ting; Manoharan, Vijayan; Shin, Su-Ryon; Damilano, Alessia; Annabi, Nasim; Dokmeci, Mehmet Remzi; Takayama, Shuichi; Khademhosseini, Ali

2015-01-01

We have designed and fabricated a miniature microscope from off-the-shelf components and a webcam, with built-in fluorescence capability for biomedical applications. The mini-microscope was able to detect both biochemical parameters, such as cell/tissue viability (e.g. live/dead assay), and biophysical properties of the microenvironment such as oxygen levels in microfabricated tissues based on an oxygen-sensitive fluorescent dye. This mini-microscope has adjustable magnifications from 8-60×, achieves a resolution as high as <2 μm, and possesses a long working distance of 4.5 mm (at a magnification of 8×). The mini-microscope was able to chronologically monitor cell migration and analyze beating of microfluidic liver and cardiac bioreactors in real time, respectively. The mini-microscope system is cheap, and its modularity allows convenient integration with a wide variety of pre-existing platforms including, but not limited to, cell culture plates, microfluidic devices, and organs-on-a-chip systems. Therefore, we envision its widespread application in cell biology, tissue engineering, biosensing, microfluidics, and organs-on-chips, which can potentially replace conventional bench-top microscopy where long-term in situ and large-scale imaging/analysis is required.

Recommended placement torque when tightening an orthodontic mini-implant.

PubMed

Motoyoshi, Mitsuru; Hirabayashi, Masayuki; Uemura, Miwa; Shimizu, Noriyoshi

2006-02-01

To determine an adequate placement torque for obtaining a better success rate of mini-implants that are screwed into the buccal alveolar bone of the posterior region as an anchor for orthodontic treatment, implant placement torque (IPT) was measured. The subjects were 41 orthodontic patients (124 implants), with an average age of 24.9 years (SD 6.5 years), who had surgery to place titanium mini-implants. The peak value of IPT was measured using a torque screwdriver. The success rate of the mini-implant anchor for 124 implants was 85.5%. The mean IPT ranged from 7.2 to 13.5 N cm, depending on the location of the implants. There was a significant difference in the IPT between maxilla and mandible. The IPT in the mandible was, unexpectedly, significantly higher in the failure group than in the success group. Therefore, a large IPT should not be used always. According to our calculations of the risk ratio for failure, to raise the success rate of 1.6-mm diameter mini-implants, the recommended IPT is within the range from 5 to 10 N cm.

Injuries in Japanese Mini-Basketball Players During Practices and Games.

PubMed

Kuzuhara, Kenji; Shibata, Masashi; Uchida, Ryo

2016-12-01

Mini-basketball is one of the most popular junior sports in Japan. Mini-basketball-related injuries may increase because of early specialization. However, no reports have been published to date concerning basketball injuries in children younger than 12 years of age. To prospectively study the incidence, sites, types, and mechanisms of injuries in mini-basketball teams. Descriptive epidemiology study. Mini-basketball teams in Kobe, Japan. A total of 95 players in 7 community-based mini-basketball club teams (age range, 9 through 12 years). Data on all practice and game injuries for the 2013-2014 season were collected using an injury report form. Injury rates were calculated according to site, type, and mechanism. The overall injury rate was 3.83 per 1000 athlete-hours (AHs). The game injury rate ( 12.92/1000 AHs) was higher than the practice injury rate (3.13/1000 AHs; P < .05). The most common anatomical areas of injury during games and practices were the head and neck (36.4%, 4.70/1000 AHs) and the upper limbs (47.8%, 1.50/1000 AHs). Sprains (42.9%, n = 39) were the most common type of injuries overall, followed by contusions (29.7%, n = 27). Most game injuries resulted from body contact (45.5%, 5.87/1000 AHs), whereas most practice injuries resulted from other contact (56.5%, 1.77/1000 AHs). Game injury rates were higher than practice injury rates in Japanese mini-basketball players. The high practice injury rate in this study may be due to specific factors related to growth, such as individual differences in height, or to skills, such as inexperience in ball handling.

Rasch analysis of the Mini-Mental Adjustment to Cancer Scale (mini-MAC) among a heterogeneous sample of long-term cancer survivors: A cross-sectional study

PubMed Central

2012-01-01

Background The mini-Mental Adjustment to Cancer Scale (mini-MAC) is a well-recognised, popular measure of coping in psycho-oncology and assesses five cancer-specific coping strategies. It has been suggested that these five subscales could be grouped to form the over-arching adaptive and maladptive coping subscales to facilitate the interpretation and clinical application of the scale. Despite the popularity of the mini-MAC, few studies have examined its psychometric properties among long-term cancer survivors, and further validation of the mini-MAC is needed to substantiate its use with the growing population of survivors. Therefore, this study examined the psychometric properties and dimensionality of the mini-MAC in a sample of long-term cancer survivors using Rasch analysis. Methods RUMM 2030 was used to analyse the mini-MAC data (n=851). Separate Rasch analyses were conducted for each of the original mini-MAC subscales as well as the over-arching adaptive and maladaptive coping subscales to examine summary and individual model fit statistics, person separation index (PSI), response format, local dependency, targeting, item bias (or differential item functioning -DIF), and dimensionality. Results For the fighting spirit, fatalism, and helplessness-hopelessness subscales, a revised three-point response format seemed more optimal than the original four-point response. To achieve model fit, items were deleted from four of the five subscales – Anxious Preoccupation items 7, 25, and 29; Cognitive Avoidance items 11 and 17; Fighting Spirit item 18; and Helplessness-Hopelessness items 16 and 20. For those subscales with sufficient items, analyses supported unidimensionality. Combining items to form the adaptive and maladaptive subscales was partially supported. Conclusions The original five subscales required item deletion and/or rescaling to improve goodness of fit to the Rasch model. While evidence was found for overarching subscales of adaptive and maladaptive

Solar Photovoltaic Array With Mini-Dome Fresnel Lenses

NASA Technical Reports Server (NTRS)

Piszczor, Michael F., Jr.; O'Neill, Mark J.

1994-01-01

Mini-dome Fresnel lenses concentrate sunlight onto individual photovoltaic cells. Facets of Fresnel lens designed to refract incident light at angle of minimum deviation to minimize reflective losses. Prismatic cover on surface of each cell reduces losses by redirecting incident light away from metal contacts toward bulk of semiconductor, where it is usefully absorbed. Simple design of mini-dome concentrator array easily adaptable to automated manufacturing techniques currently used by semiconductor industry. Attractive option for variety of future space missions.

Satisfaction, function and repair integrity after arthroscopic versus mini-open rotator cuff repair.

PubMed

Barnes, L A Fink; Kim, H M; Caldwell, J-M; Buza, J; Ahmad, C S; Bigliani, L U; Levine, W N

2017-02-01

Advances in arthroscopic techniques for rotator cuff repair have made the mini-open approach less popular. However, the mini-open approach remains an important technique for repair for many surgeons. The aims of this study were to compare the integrity of the repair, the function of the shoulder and satisfaction post-operatively using these two techniques in patients aged > 50 years. We identified 22 patients treated with mini-open and 128 patients treated with arthroscopic rotator cuff repair of July 2007 and June 2011. The mean follow-up was two years (1 to 5). Outcome was assessed using the American Shoulder and Elbow Surgeons (ASES) and Simple Shoulder Test (SST) scores, and satisfaction. The integrity of the repair was assessed using ultrasonography. A power analysis ensured sufficient enrolment. There was no statistically significant difference between the age, function, satisfaction, or pain scores (p > 0.05) of the two groups. The integrity of the repair and the mean SST scores were significantly better in the mini-open group (91% of mini-open repairs were intact versus 60% of arthroscopic repairs, p = 0.023; mean SST score 10.9 (standard deviation (sd) 1.3) in the mini-open group; 8.9 (sd 3.5) in arthroscopic group; p = 0.003). The ASES scores were also higher in the mini-open group (mean ASES score 91.0 (sd 10.5) in mini-open group; mean 82.70 (sd 19.8) in the arthroscopic group; p = 0.048). The integrity of the repair and function of the shoulder were better after a mini-open repair than after arthroscopic repair of a rotator cuff tear in these patients. The functional difference did not translate into a difference in satisfaction. Mini-open rotator cuff repair remains a useful technique despite advances in arthroscopy. Cite this article: Bone Joint J 2017;99-B:245-9. ©2017 The British Editorial Society of Bone & Joint Surgery.

Contrasting influences of Drosophila white/mini-white on ethanol sensitivity in two different behavioral assays

PubMed Central

Chan, Robin F.; Lewellyn, Lara; DeLoyht, Jacqueline M.; Sennett, Kristyn; Coffman, Scarlett; Hewitt, Matthew; Bettinger, Jill C.; Warrick, John M.; Grotewiel, Mike

2014-01-01

Background The fruit fly Drosophila melanogaster has been used extensively to investigate genetic mechanisms of ethanol-related behaviors. Many past studies in flies, including studies from our laboratory, have manipulated gene expression using transposons carrying the genetic-phenotypic marker mini-white, a derivative of the endogenous gene white. Whether the mini-white transgenic marker or the endogenous white gene influence behavioral responses to acute ethanol exposure in flies has not been systematically investigated. Methods We manipulated mini-white and white expression via (i) transposons marked with mini-white, (ii) RNAi against mini-white and white and (iii) a null allele of white. We assessed ethanol sensitivity and tolerance using a previously described eRING assay (based on climbing in the presence of ethanol) and an assay based on ethanol-induced sedation. Results In eRING assays, ethanol-induced impairment of climbing correlated inversely with expression of the mini-white marker from a series of transposon insertions. Additionally, flies harboring a null allele of white or flies with RNAi-mediated knockdown of mini-white were significantly more sensitive to ethanol in eRING assays than controls expressing endogenous white or the mini-white marker. In contrast, ethanol sensitivity and rapid tolerance measured in the ethanol sedation assay were not affected by decreased expression of mini-white or endogenous white in flies. Conclusions Ethanol sensitivity measured in the eRING assay is noticeably influenced by white and mini-white, making eRING problematic for studies on ethanol-related behavior in Drosophila using transgenes marked with mini-white. In contrast, the ethanol sedation assay described here is a suitable behavioral paradigm for studies on ethanol sedation and rapid tolerance in Drosophila including those that use widely available transgenes marked with mini-white. PMID:24890118

Integrating Low-Cost Mems Accelerometer Mini-Arrays (mama) in Earthquake Early Warning Systems

NASA Astrophysics Data System (ADS)

Nof, R. N.; Chung, A. I.; Rademacher, H.; Allen, R. M.

2016-12-01

Current operational Earthquake Early Warning Systems (EEWS) acquire data with networks of single seismic stations, and compute source parameters assuming earthquakes to be point sources. For large events, the point-source assumption leads to an underestimation of magnitude, and the use of single stations leads to large uncertainties in the locations of events outside the network. We propose the use of mini-arrays to improve EEWS. Mini-arrays have the potential to: (a) estimate reliable hypocentral locations by beam forming (FK-analysis) techniques; (b) characterize the rupture dimensions and account for finite-source effects, leading to more reliable estimates for large magnitudes. Previously, the high price of multiple seismometers has made creating arrays cost-prohibitive. However, we propose setting up mini-arrays of a new seismometer based on low-cost (<$150), high-performance MEMS accelerometer around conventional seismic stations. The expected benefits of such an approach include decreasing alert-times, improving real-time shaking predictions and mitigating false alarms. We use low-resolution 14-bit Quake Catcher Network (QCN) data collected during Rapid Aftershock Mobilization Program (RAMP) in Christchurch, NZ following the M7.1 Darfield earthquake in September 2010. As the QCN network was so dense, we were able to use small sub-array of up to ten sensors spread along a maximum area of 1.7x2.2 km2 to demonstrate our approach and to solve for the BAZ of two events (Mw4.7 and Mw5.1) with less than ±10° error. We will also present the new 24-bit device details, benchmarks, and real-time measurements.

Replacing Resistance Heating with Mini-Split Heat Pumps, Sharon, Connecticut (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Mini-split heat pumps can provide space heating and cooling in many climates and are relatively affordable. These and other features make them potentially suitable for retrofitting into multifamily buildings in cold climates to replace electric resistance heating or other outmoded heating systems. This report investigates the suitability of mini-split heat pumps for multifamily retrofits. Various technical and regulatory barriers are discussed and modeling was performed to compare long-term costs of substituting mini-splits for a variety of other heating and cooling options. A number of utility programs have retrofit mini-splits in both single family and multifamily residences. Two such multifamily programsmore » are discussed in detail.« less

Arc-to-Arc mini-sling 1999: a critical analysis of concept and technology.

PubMed

Palma, Paulo

2011-01-01

The aim of this study was to critically review the Arc-to-Arc mini-sling (Palma's technique) a less invasive mid-urethral sling using bovine pericardium as the sling material. The Arc-to-Arc mini-sling, using bovine pericardium, was the first published report of a mini-sling, in 1999. The technique was identical to the "tension-free tape" operation, midline incision and dissection of the urethra. The ATFP (white line) was identified by blunt dissection, and the mini-sling was sutured to the tendinous arc on both sides with 2 polypropylene 00 sutures. The initial results were encouraging, with 9/10 patients cured at the 6 weeks post-operative visit. However, infection and extrusion of the mini-sling resulted in sling extrusion and removal, with 5 patients remaining cured at 12 months. The Arc-to-Arc mini-sling was a good concept, but failed because of the poor technology available at that time. Further research using new materials and better technology has led to new and safer alternatives for the management of stress urinary incontinence.

Mini rainfall simulation for assessing soil erodibility

NASA Astrophysics Data System (ADS)

Peters, Piet; Palese, Dina; Baartman, Jantiene

2016-04-01

The mini rainfall simulator is a small portable rainfall simulator to determine erosion and water infiltration characteristics of soils. The advantages of the mini rainfall simulator are that it is suitable for soil conservation surveys and light and easy to handle in the field. Practical experience over the last decade has shown that the used 'standard' shower is a reliable method to assess differences in erodibility due to soil type and/or land use. The mini rainfall simulator was used recently in a study on soil erosion in olive groves (Ferrandina-Italy). The propensity to erosion of a steep rain-fed olive grove (mean slope ~10%) with a sandy loam soil was evaluated by measuring runoff and sediment load under extreme rain events. Two types of soil management were compared: spontaneous grass as a ground cover (GC) and tillage (1 day (T1) and 10 days after tillage (T2)). Results indicate that groundcover reduced surface runoff to approximately one-third and soil-losses to zero compared with T1. The runoff between the two tilled plots was similar, although runoff on T1 plots increased steadily over time whereas runoff on T2 plots remained stable.

Translational mini-screw implant research.

PubMed

Rossouw, Emile

2014-09-01

It is important to thoroughly test new materials as well as techniques when these innovations are to be utilized in the human clinical situation. Translational research fills this important niche. The purpose of translational research is to establish the continuity of evidence from the laboratory to the clinic and in so-doing, provide evidence that the material is functioning appropriately and that the process in the human will be successful. This concept applies to the mini-screw implant; which, has been very successfully introduced into the orthodontic armamentarium over the last decade for application as a temporary anchorage device. The examples of translational research that will be illustrated in this paper have paved the way to ensure that clinicians have evidence to confidently utilize mini-screw implants in orthodontic practice. Needless to say, more studies are needed to ensure a safe, effective and efficient manner to practice orthodontics. © 2014 British Orthodontic Society.

Injuries in Japanese Mini-Basketball Players During Practices and Games

PubMed Central

Kuzuhara, Kenji; Shibata, Masashi; Uchida, Ryo

2016-01-01

Context: Mini-basketball is one of the most popular junior sports in Japan. Mini-basketball–related injuries may increase because of early specialization. However, no reports have been published to date concerning basketball injuries in children younger than 12 years of age. Objective: To prospectively study the incidence, sites, types, and mechanisms of injuries in mini-basketball teams. Design: Descriptive epidemiology study. Setting: Mini-basketball teams in Kobe, Japan. Patients or Other Participants: A total of 95 players in 7 community-based mini-basketball club teams (age range, 9 through 12 years). Main Outcome Measure(s): Data on all practice and game injuries for the 2013–2014 season were collected using an injury report form. Injury rates were calculated according to site, type, and mechanism. Results: The overall injury rate was 3.83 per 1000 athlete-hours (AHs). The game injury rate (12.92/1000 AHs) was higher than the practice injury rate (3.13/1000 AHs; P < .05). The most common anatomical areas of injury during games and practices were the head and neck (36.4%, 4.70/1000 AHs) and the upper limbs (47.8%, 1.50/1000 AHs). Sprains (42.9%, n = 39) were the most common type of injuries overall, followed by contusions (29.7%, n = 27). Most game injuries resulted from body contact (45.5%, 5.87/1000 AHs), whereas most practice injuries resulted from other contact (56.5%, 1.77/1000 AHs). Conclusions: Game injury rates were higher than practice injury rates in Japanese mini-basketball players. The high practice injury rate in this study may be due to specific factors related to growth, such as individual differences in height, or to skills, such as inexperience in ball handling. PMID:27922287

Research for the Classroom: Mini Vocabulary Lessons for Maximum Recall

ERIC Educational Resources Information Center

Sovereen, Deanne

2013-01-01

"Research for the Classroom" publishes mini-studies of ELA classroom practices and suggests ways in which high school and middle school English teachers may study the effectiveness of their pedagogy. The author of this mini-study notes that it takes around six minutes per day of instructional time for students to remember most of the…

Review of Strategies and Technologies for Demand-Side Management on Isolated Mini-Grids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harper, Meg

This review provides an overview of strategies and currently available technologies used for demandside management (DSM) on mini-grids throughout the world. For the purposes of this review, mini-grids are defined as village-scale electricity distribution systems powered by small local generation sources and not connected to a main grid.1 Mini-grids range in size from less than 1 kW to several hundred kW of installed generation capacity and may utilize different generation technologies, such as micro-hydro, biomass gasification, solar, wind, diesel generators, or a hybrid combination of any of these. This review will primarily refer to AC mini-grids, though much of themore » discussion could apply to DC grids as well. Many mini-grids include energy storage, though some rely solely on real-time generation.« less

The Atmospheric Diversity of Mini-Neptunes in Multi-planet Systems

NASA Astrophysics Data System (ADS)

Crossfield, Ian

2017-08-01

Mini-Neptunes, planets 2-4 times the size of the Earth, are anintriguing population. They are an abundant outcome of planetformation and occur around more than a quarter of all stars -- yetthey are absent in the Solar System. Mini-Neptunes bridge the gapbetween terrestrial planets and gas giants, and atmospherecharacterization of these planets has much to reveal about their currentproperties, origins, and evolutionary histories. However, only a handful of mini-Neptunes have been amenable to atmospheric study so far.We propose a survey of four mini-Neptunes recently discovered by ourteam around bright, nearby stars. These observations will nearlydouble the number of planets in this size range with measuredtransmission spectra. Our observations will yield high-precisionconstraints on the planets' atmospheric metallicities, elementalabundances, C/O ratios, and aerosol content. With a greatly expandedmini-Neptune sample, we will identify trends in planet properties as afunction of equilibrium temperature, UV irradiation, planet mass, andstellar spectral type. These trends will also identify specificpromising targets for further study with JWST, and will help usprioritize follow-up and atmospheric characterization of themany small planets expected from the TESS survey.

The Mini-Balance Evaluation Systems Test (Mini-BESTest) Demonstrates Higher Accuracy in Identifying Older Adult Participants With History of Falls Than Do the BESTest, Berg Balance Scale, or Timed Up and Go Test.

PubMed

Yingyongyudha, Anyamanee; Saengsirisuwan, Vitoon; Panichaporn, Wanvisa; Boonsinsukh, Rumpa

2016-01-01

Balance deficits a significant predictor of falls in older adults. The Balance Evaluation Systems Test (BESTest) and the Mini-Balance Evaluation Systems Test (Mini-BESTest) are tools that may predict the likelihood of a fall, but their capabilities and accuracies have not been adequately addressed. Therefore, this study aimed at examining the capabilities of the BESTest and Mini-BESTest for identifying older adult with history of falls and comparing the participants with history of falls identification accuracy of the BESTest, Mini-BESTest, Berg Balance Scale (BBS), and the Timed Up and Go Test (TUG) for identifying participants with a history of falls. Two hundred healthy older adults with a mean age of 70 years were classified into participants with and without history of fall groups on the basis of their 12-month fall history. Their balance abilities were assessed using the BESTest, Mini-BESTest, BBS, and TUG. An analysis of the resulting receiver operating characteristic curves was performed to calculate the area under the curve (AUC), sensitivity, specificity, cutoff score, and posttest accuracy of each. The Mini-BESTest showed the highest AUC (0.84) compared with the BESTest (0.74), BBS (0.69), and TUG (0.35), suggesting that the Mini-BESTest had the highest accuracy in identifying older adult with history of falls. At the cutoff score of 16 (out of 28), the Mini-BESTest demonstrated a posttest accuracy of 85% with a sensitivity of 85% and specificity of 75%. The Mini-BESTest had the highest posttest accuracy, with the others having results of 76% (BESTest), 60% (BBS), and 65% (TUG). The Mini-BESTest is the most accurate tool for identifying older adult with history of falls compared with the BESTest, BBS, and TUG.

Methods for roof-top mini-arrays

NASA Astrophysics Data System (ADS)

Hazen, W. E.; Hazen, E. S.

1985-08-01

To test the idea of the Linsley effect mini array for the study of giant air showers, it is desirable to have a trigger that exploits the effect itself. In addition to the trigger, it is necessary to have a method for measuring the relative arrival times of the particle swarm selected by the trigger. Since the idea of mini arrays is likely to appeal to small research groups, it is desirable to try to design relatively simple and inexpensive methods, and methods that utilize existing detectors. Clusters of small detectors have been designed for operation in the local particle density realm where the probability of or = 2 particles per detector is small. Consequently, this method can discriminate pulses from each detector and thenceforth deal mainly with logic pulses.

Mini vs standard percutaneous nephrolithotomy for renal stones: a comparative study.

PubMed

ElSheemy, Mohammed S; Elmarakbi, Akram A; Hytham, Mohammed; Ibrahim, Hamdy; Khadgi, Sanjay; Al-Kandari, Ahmed M

2018-03-16

To compare the outcome of mini-percutaneous nephrolithotomy (Mini-PNL) versus standard-PNL for renal stones. Retrospective study was performed between March 2010 and May 2013 for patients treated by Mini-PNL or standard-PNL through 18 and 30 Fr tracts, respectively, using pneumatic lithotripsy. Semirigid ureteroscope (8.5/11.5 Fr) was used for Mini-PNL and 24 Fr nephroscope for standard-PNL. Both groups were compared in stone free rate(SFR), complications and operative time using Student-t, Mann-Whitney, Chi square or Fisher's exact tests as appropriate in addition to logistic regression analysis. P < 0.05 was considered statistically significant. Mini-PNL (378) and standard-PNL (151) were nearly comparable in patients and stones criteria including stone burden (3.77 ± 2.21 vs 3.77 ± 2.43 cm 2 ; respectively). There was no significant difference in number of tracts or supracostal puncture. Mini-PNL had longer operative time (68.6 ± 29.09 vs 60.49 ± 11.38 min; p = 0.434), significantly shorter hospital stay (2.43 ± 1.46 vs 4.29 ± 1.28 days) and significantly higher rate of tubeless PNL (75.1 vs 4.6%). Complications were significantly higher in standard-PNL (7.9 vs 20.5%; p < 0.001). SFR was significantly lower in Mini-PNL (89.9 vs 96%; p = 0.022). This significant difference was found with multiple stones and large stone burden (> 2 cm 2 ), but the SFR was comparable between both groups with single stone or stone burden ≤ 2 cm. Logistic regression analysis confirmed significantly higher complications and SFR with standard-PNL but with significantly shorter operative time. Mini-PNL has significantly lower SFR when compared to standard-PNL (but clinically comparable) with markedly reduced complications and hospital stay. Most of cases can be performed tubeless. The significant difference in SFR was found with multiple stones or large stone burden (> 2 cm 2 ), but not with single stones or stone burden�

Coordinate expression of AOS genes and JA accumulation: JA is not required for initiation of closing layer in wound healing tubers

USDA-ARS?s Scientific Manuscript database

Wounding induces a series of coordinated physiological responses essential for protection and healing of the damaged tissue. Wound-induced formation of jasmonic acid (JA) is important in defense responses in leaves, but comparatively little is known about the induction of JA biosynthesis and its ro...

Rational Design of Mini-Cas9 for Transcriptional Activation.

PubMed

Ma, Dacheng; Peng, Shuguang; Huang, Weiren; Cai, Zhiming; Xie, Zhen

2018-04-20

Nuclease dead Cas9 (dCas9) has been widely used for modulating gene expression by fusing with different activation or repression domains. However, delivery of the CRISPR/Cas system fused with various effector domains in a single adeno-associated virus (AAV) remains challenging due to the payload limit. Here, we engineered a set of downsized variants of Cas9 including Staphylococcus aureus Cas9 (SaCas9) that retained DNA binding activity by deleting conserved functional domains. We demonstrated that fusing FokI nuclease domain to the N-terminal of the minimal SaCas9 (mini-SaCas9) or to the middle of the split mini-SaCas9 can trigger efficient DNA cleavage. In addition, we constructed a set of compact transactivation domains based on the tripartite VPR activation domain and self-assembled arrays of split SpyTag:SpyCatch peptides, which are suitable for fusing to the mini-SaCas9. Lastly, we produced a single AAV containing the mini-SaCas9 fused with a downsized transactivation domain along with an optimized gRNA expression cassette, which showed efficient transactivation activity. Our results highlighted a practical approach to generate down-sized CRISPR/Cas9 and gene activation systems for in vivo applications.

Validation and Diagnostic Efficiency of the Mini-SPIN in Spanish-Speaking Adolescents.

PubMed

Garcia-Lopez, LuisJoaquín; Moore, Harry T A

2015-01-01

Social Anxiety Disorder (SAD) is one of the most common mental disorders in adolescence. Many validated psychometric tools are available to diagnose individuals with SAD efficaciously. However, there is a demand for shortened self-report instruments that identify adolescents at risk of developing SAD. We validate the Mini-SPIN and its diagnostic efficiency in overcoming this problem in Spanish-speaking adolescents in Spain. The psychometric properties of the 3-item Mini-SPIN scale for adolescents were assessed in a community (study 1) and clinical sample (study 2). Study 1 consisted of 573 adolescents, and found the Mini-SPIN to have appropriate internal consistency and high construct validity. Study 2 consisted of 354 adolescents (147 participants diagnosed with SAD and 207 healthy controls). Data revealed that the Mini-SPIN has good internal consistency, high construct validity and adequate diagnostic efficiency. Our findings suggest that the Mini-SPIN has good psychometric properties on clinical and healthy control adolescents and general population, which indicates that it can be used as a screening tool in Spanish-speaking adolescents. Cut-off scores are provided.

Effect of recycling protocol on mechanical strength of used mini-implants.

PubMed

Estelita, Sérgio; Janson, Guilherme; Chiqueto, Kelly; Ferreira, Eduardo Silveira

2014-01-01

Purpose. This study evaluated the influence of recycling process on the torsional strength of mini-implants. Materials and Methods. Two hundred mini-implants were divided into 4 groups with 50 screws equally distributed in five diameters (1.3 to 1.7 mm): control group (CG): unused mini-implants, G1: mini-implants inserted in pig iliac bone and removed, G2: same protocol of group 1 followed by sonication for cleaning and autoclave sterilization, and G3: same insertion protocol of group 1 followed by sonication for cleaning before and after sandblasting (Al2O3-90 µ) and autoclave sterilization. G2 and G3 mini-implants were weighed after recycling process to evaluate weight loss (W). All the screws were broken to determine the fracture torque (FT). The influence of recycling process on FT and W was evaluated by ANOVA, Mann-Whitney, and multiple linear regression analysis. Results. FT was not influenced by recycling protocols even when sandblasting was added. Sandblasting caused weight loss due to abrasive mechanical stripping of screw surface. Screw diameter was the only variable that affected FT. Conclusions. Torsional strengths of screws that underwent the recycling protocols were not changed. Thus, screw diameter choice can be a more critical step to avoid screw fracture than recycling decision.

Design and Performance Evaluation of a UWB Communication and Tracking System for Mini-AERCam

NASA Technical Reports Server (NTRS)

Barton, Richard J.

2005-01-01

NASA Johnson Space Center (JSC) is developing a low-volume, low-mass, robotic free-flying camera known as Mini-AERCam (Autonomous Extra-vehicular Robotic Camera) to assist the International Space Station (ISS) operations. Mini-AERCam is designed to provide astronauts and ground control real-time video for camera views of ISS. The system will assist ISS crewmembers and ground personnel to monitor ongoing operations and perform visual inspections of exterior ISS components without requiring extravehicular activity (EAV). Mini-AERCam consists of a great number of subsystems. Many institutions and companies have been involved in the R&D for this project. A Mini-AERCam ground control system has been studied at Texas A&M University [3]. The path planning and control algorithms that direct the motions of Mini-AERCam have been developed through the joint effort of Carnegie Mellon University and the Texas Robotics and Automation Center [5]. NASA JSC has designed a layered control architecture that integrates all functions of Mini-AERCam [8]. The research described in this report is part of a larger effort focused on the communication and tracking subsystem that is designed to perform three major tasks: 1. To transmit commands from ISS to Mini-AERCam for control of robotic camera motions (downlink); 2. To transmit real-time video from Mini-AERCam to ISS for inspections (uplink); 3. To track the position of Mini-AERCam for precise motion control. The ISS propagation environment is unique due to the nature of the ISS structure and multiple RF interference sources [9]. The ISS is composed of various truss segments, solar panels, thermal radiator panels, and modules for laboratories and crew accommodations. A tracking system supplemental to GPS is desirable both to improve accuracy and to eliminate the structural blockage due to the close proximity of the ISS which could at times limit the number of GPS satellites accessible to the Mini-AERCam. Ideally, the tracking system will

LQC control for the Mini-Mast experiment

NASA Technical Reports Server (NTRS)

Montgomery, R. C.; Ghosh, D.

1988-01-01

The Mini-Mast system is briefly reviewed, and results of a simulation study of the LQG control for the Mini-Mast experiment are reported. In particular, attention is given to problems and limitations related to the testing of control laws using reaction mass actuators, such as accounting for force and stroke limits of these devices. The local controller used in the study and the algorithm for converting the force commands of the LQG algorithm to position commands for the reaction mass device are described. It is shown that the LQG generated damping is reduced when a local controller is used and the position command is not saturated; it drops still further when the position command is saturated.

Surgical management of fractured orthodontic mini- implant- a case report.

PubMed

Desai, Manthan; Jain, Anoop; Sumra, Nida

2015-01-01

The idea of absolute anchorage has always been an elusive goal for clinicians. Orthodontic mini-implants or temporary anchorage devices allow tooth movements previously thought to be impossible or difficult. Although extensive literature exists on use of temporary anchorage devices, their failures have been hardly focused upon, especially implant fracture. The following case report describes successful management of fractured orthodontic mini-implant.

NASA Johnson Space Center: Mini AERCam Testing with GSS6560

NASA Technical Reports Server (NTRS)

Cryant, Scott P.

2004-01-01

This slide presentation reviews the testing of the Miniature Autonomous Extravehicular Robotic Camera (Mini AERCam) with the GPS/SBAS simulation system, GSS6560. There is a listing of several GPS based programs at NASA Johnson, including the testing of Shuttle testing of the GPS system. Including information about Space Integrated GPS/INS (SIGI) testing. There is also information about the standalone ISS SIGI test,and testing of the SIGI for the Crew Return Vehicle. The Mini AERCam is a small, free-flying camera for remote inspections of the ISS, it uses precise relative navigation with differential carrier phase GPS to provide situational awareness to operators. The closed loop orbital testing with and without the use of the GSS6550 system of the Mini AERCam system is reviewed.

Sparse reconstruction of liver cirrhosis from monocular mini-laparoscopic sequences

NASA Astrophysics Data System (ADS)

Marcinczak, Jan Marek; Painer, Sven; Grigat, Rolf-Rainer

2015-03-01

Mini-laparoscopy is a technique which is used by clinicians to inspect the liver surface with ultra-thin laparoscopes. However, so far no quantitative measures based on mini-laparoscopic sequences are possible. This paper presents a Structure from Motion (SfM) based methodology to do 3D reconstruction of liver cirrhosis from mini-laparoscopic videos. The approach combines state-of-the-art tracking, pose estimation, outlier rejection and global optimization to obtain a sparse reconstruction of the cirrhotic liver surface. Specular reflection segmentation is included into the reconstruction framework to increase the robustness of the reconstruction. The presented approach is evaluated on 15 endoscopic sequences using three cirrhotic liver phantoms. The median reconstruction accuracy ranges from 0.3 mm to 1 mm.

The MiniCLEAN Dark Matter Experiment

NASA Astrophysics Data System (ADS)

Schnee, Richard; Deap/Clean Collaboration

2011-10-01

The MiniCLEAN dark matter experiment exploits a single-phase liquid argon (LAr) detector, instrumented with photomultiplier tubes submerged in the cryogen with nearly 4 π coverage of a 500 kg target (150 kg fiducial) mass. The high light yield and large difference in singlet/triplet scintillation time-profiles in LAr provide effective defense against radioactive backgrounds through pulse-shape discrimination and event position reconstruction. The detector is also designed for a liquid neon target which, in the event of a positive signal in LAr, will enable an independent verification of backgrounds and provide a unique test of the expected A2 dependence of the WIMP interaction rate. The conceptually simple design can be scaled to target masses in excess of 10 tons in a relatively straightforward and economic manner. The experimental technique and current status of MiniCLEAN will be summarized.

Mini-Term: Exploring Career Choices

ERIC Educational Resources Information Center

Velcich, Joann; Mitchell, Mary Ellen

1976-01-01

Mini-term (an out-of-school, short-term, field experience) was implemented at the University of Knoxville so students could examine the work environment and job responsibilities of a specific career. Increase in student participation and positive student comments have provided the impetus for revising the program to meet future needs. (KRP)

"Mini", "Midi" and the Student.

ERIC Educational Resources Information Center

Edwards, Perry; Broadwell, Bruce

Mini- and midi-computers have been introduced into the computer science program at Sierra College to afford students more direct contact with computers. The college's administration combined with the Science and Business departments to share the expense and utilization of the program. The National Cash Register Century 100 and the Data General…

The ASTRI/CTA mini-array software system

NASA Astrophysics Data System (ADS)

Tosti, Gino; Schwarz, Joseph; Antonelli, Lucio Angelo; Trifoglio, Massimo; Catalano, Osvaldo; Maccarone, Maria Concetta; Leto, Giuseppe; Gianotti, Fulvio; Canestrari, Rodolfo; Giro, Enrico; Fiorini, Mauro; La Palombara, Nicola; Pareschi, Giovanni; Stringhetti, Luca; Vercellone, Stefano; Conforti, Vito; Tanci, Claudio; Bruno, Pietro; Grillo, Alessandro; Testa, Vincenzo; di Paola, Andrea; Gallozzi, Stefano

2014-07-01

ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) is a Flagship Project financed by the Italian Ministry of Education, University and Research, and led by INAF, the Italian National Institute of Astrophysics. The main goals of the ASTRI project are the realization of an end-to-end prototype of a Small Size Telescope (SST) for the Cherenkov Telescope Array (CTA) in a dual- mirror configuration (SST-2M) and, subsequently, of a mini-array comprising seven SST-2M telescopes. The mini-array will be placed at the final CTA Southern Site, which will be part of the CTA seed array, around which the whole CTA observatory will be developed. The Mini-Array Software System (MASS) will provide a comprehensive set of tools to prepare an observing proposal, to perform the observations specified therein (monitoring and controlling all the hardware components of each telescope), to analyze the acquired data online and to store/retrieve all the data products to/from the archive. Here we present the main features of the MASS and its first version, to be tested on the ASTRI SST-2M prototype that will be installed at the INAF observing station located at Serra La Nave on Mount Etna in Sicily.

SenseWearMini and Actigraph GT3X Accelerometer Classification of Observed Sedentary and Light-Intensity Physical Activities in a Laboratory Setting.

PubMed

Feehan, Lynne M; Goldsmith, Charles H; Leung, April Y F; Li, Linda C

Purpose: To compare the ability of SenseWear Mini (SWm) and Actigraph GT3X (AG 3 ) accelerometers to differentiate between healthy adults' observed sedentary and light activities in a laboratory setting. Methods: The 22 participants (15 women, 7 men), ages 19 to 72 years, wore SWm and AG 3 monitors and performed five sedentary and four light activities for 5 minutes each while observed in a laboratory setting. Performance was examined through comparisons of accuracy, sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios. Correct identification of both types of activities was examined using area under the receiver operating characteristic curve (AUC). Results: Both monitors demonstrated excellent ability to identify sedentary activities (sensitivity>0.89). The SWm monitor was better at identifying light activities (specificity 0.61-0.71) than the AG 3 monitor (specificity 0.27-0.47) and thus also showed a greater ability to correctly identify both sedentary and light activities (SWm AUC 0.84; AG 3 AUC 0.62-0.73). Conclusions: SWm may be a more suitable monitor for detecting time spent in sedentary and light-intensity activities. This finding has clinical and research relevance for evaluation of time spent in lower intensity physical activities by sedentary adults.

Environmental Assessment: Proposed Construction of Army and Air Force Exchange Service Mini-Mall

DTIC Science & Technology

2003-10-01

fast food style restaurant would be accommodated in the mini-mall. Data on electrical consumption for the Burger King restaurant at MAFB (Building...MAFB-Gunter Annex. Assuming the new restaurant in the mini-mall consumes approximately the same quantity of electricity annually as the Burger King ...in the mini-mall. Data on natural gas consumption for the Burger King restaurant at MAFB (Building 1087) in FY 2001 reveals that this facility

Mandibular Overdentures Retained by Two Mini-Implants: A Seven-Year Retention and Satisfaction Study.

PubMed

Catalán, Alfonso; Martínez, Alejandra; Marchesani, Francisco; González, Urcesino

2016-07-01

Patients with atrophic edentulous ridges generally have problems with retention, therapeutic satisfaction, and comfort with their complete dentures. An alternative treatment to assist in improving retention and stability involves the use of mini-implants. The aim of this study was to evaluate the retention of mandibular overdentures connected to two mini-implants and overall patient satisfaction with them. Seven patients with atrophic mandibular ridges (Type 4D Misch classification), aged 62 to 74 years old were rehabilitated with complete dentures. In each patient, two mini-implants measuring 15 or 13 mm in length and 1.8 mm in diameter were placed. After 15 days, overdentures were connected to the mini-implants with O-ring attachments. In each patient, retention of the overdentures was measured, and a survey of therapeutic satisfaction before and after connection to the mini-implants was administered. Prosthesis retention was measured with a digital dynamometer at 1 month, 6 months, and 2, 3, 5, and 7 years after mini-implant placement. Patient satisfaction was assessed with a survey. Data were analyzed with Student's t-test (satisfaction survey) and the Friedman test (retention measurements and satisfaction survey). The initial retention values (0.34 to 0.63 N without mini-implants) varied significantly (p ≤ 0.050). These values were less than the subsequent measurements of 3.92 to 9.64 N, taken after placement of the mini-implants and connecting them to the dentures. Satisfaction was good to very good over the 7-year observation period. Mucosa and peri-implant bone showed no pathological changes. In this limited sample size clinical study the results indicated that after connecting mandibular overdentures to two mini-implants, patient satisfaction significantly increased and retention significantly improved during the 7-year observation period. © 2015 by the American College of Prosthodontists.

Beyond standard model searches in the MiniBooNE experiment

DOE PAGES

Katori, Teppei; Conrad, Janet M.

2014-08-05

Tmore » he MiniBooNE experiment has contributed substantially to beyond standard model searches in the neutrino sector. he experiment was originally designed to test the Δ m 2 ~ 1 eV 2 region of the sterile neutrino hypothesis by observing ν e ( ν - e ) charged current quasielastic signals from a ν μ ( ν - μ ) beam. MiniBooNE observed excesses of ν e and ν - e candidate events in neutrino and antineutrino mode, respectively. o date, these excesses have not been explained within the neutrino standard model ( ν SM); the standard model extended for three massive neutrinos. Confirmation is required by future experiments such as MicroBooNE. MiniBooNE also provided an opportunity for precision studies of Lorentz violation. he results set strict limits for the first time on several parameters of the standard-model extension, the generic formalism for considering Lorentz violation. Most recently, an extension to MiniBooNE running, with a beam tuned in beam-dump mode, is being performed to search for dark sector particles. In addition, this review describes these studies, demonstrating that short baseline neutrino experiments are rich environments in new physics searches.« less

How does feedback in mini-CEX affect students' learning response?

PubMed

Sudarso, Sulistiawati; Rahayu, Gandes Retno; Suhoyo, Yoyo

2016-12-19

This study was aimed to explore students' learning response toward feedback during mini-CEX encounter. This study used a phenomenological approach to identify the students' experiences toward feedback during mini-CEX encounter. Data was collected using Focus Group Discussion (FGD) for all students who were in their final week of clerkship in the internal medicine rotation. There were 4 FGD groups (6 students for each group). All FGD were audio-taped and transcribed verbatim. The FGD transcripts were analyzed thematically and managed using Atlas-ti (version 7.0). Feedback content and the way of providing feedback on mini-CEX stimulated students' internal process, including self-reflection, emotional response, and motivation. These internal processes encouraged the students to take action or do a follow-up on the feedback to improve their learning process. In addition, there was also an external factor, namely consequences, which also influenced the students' reaction to the follow-up on feedback. In the end, this action caused several learning effects that resulted in the students' increased self-efficacy, attitude, knowledge and clinical skill. Feedback content and the way of providing feedback on mini-CEX stimulates the students' internal processes to do a follow-up on feedback. However, another external factor also affects the students' decision on the follow-up actions. The follow-ups result in various learning effects on the students. Feedback given along with summative assessment enhances learning effects on students, as well. It is suggested that supervisors of clinical education are prepared to comprehend every factor influencing feedback on mini CEX to improve the students' learning response.

Validation and Diagnostic Efficiency of the Mini-SPIN in Spanish-Speaking Adolescents

PubMed Central

Garcia-Lopez, LuisJoaquín; Moore, Harry T. A.

2015-01-01

Objectives Social Anxiety Disorder (SAD) is one of the most common mental disorders in adolescence. Many validated psychometric tools are available to diagnose individuals with SAD efficaciously. However, there is a demand for shortened self-report instruments that identify adolescents at risk of developing SAD. We validate the Mini-SPIN and its diagnostic efficiency in overcoming this problem in Spanish-speaking adolescents in Spain. Methods The psychometric properties of the 3-item Mini-SPIN scale for adolescents were assessed in a community (study 1) and clinical sample (study 2). Results Study 1 consisted of 573 adolescents, and found the Mini-SPIN to have appropriate internal consistency and high construct validity. Study 2 consisted of 354 adolescents (147 participants diagnosed with SAD and 207 healthy controls). Data revealed that the Mini-SPIN has good internal consistency, high construct validity and adequate diagnostic efficiency. Conclusions Our findings suggest that the Mini-SPIN has good psychometric properties on clinical and healthy control adolescents and general population, which indicates that it can be used as a screening tool in Spanish-speaking adolescents. Cut-off scores are provided. PMID:26317695

Mini-titins in striated and smooth molluscan muscles: structure, location and immunological crossreactivity.

PubMed

Vibert, P; Edelstein, S M; Castellani, L; Elliott, B W

1993-12-01

Invertebrate mini-titins are members of a class of myosin-binding proteins belonging to the immunoglobulin superfamily that may have structural and/or regulatory properties. We have isolated mini-titins from three molluscan sources: the striated and smooth adductor muscles of the scallop, and the smooth catch muscles of the mussel. Electron microscopy reveals flexible rod-like molecules about 0.2 micron long and 30 A wide with a distinctive polarity. Antibodies to scallop mini-titin label the A-band and especially the A/I junction of scallop striated muscle myofibrils by indirect immunofluorescence and immuno-electron microscopy. This antibody crossreacts with mini-titins in scallop smooth and Mytilus catch muscles, as well as with proteins in striated muscles from Limulus, Lethocerus (asynchronous flight muscle), and crayfish. It labels the A/I junction (I-region in Lethocerus) in these striated muscles as well as in chicken skeletal muscle. Antibodies to the repetitive immunoglobulin-like regions and also to the kinase domain of nematode twitchin crossreact with scallop mini-titin and label the A-band of scallop myofibrils. Electron microscopy of single molecules shows that antibodies to twitchin kinase bind to scallop mini-titin near one end of the molecule, suggesting how the scallop structure might be aligned with the sequence of nematode twitchin.

Mini-implants: alternative for oral rehabilitation of a child with ectodermal dysplasia.

PubMed

Mello, Bianca Zeponi Fernandes; Silva, Thiago Cruvinel; Rios, Daniela; Machado, Maria Aparecida Andrade Moreira; Valarelli, Fabrício Pinelli; Oliveira, Thais Marchini

2015-01-01

Ectodermal dysplasia is a rare congenital disease that affects several structures of ectodermal origin. The most commonly related oral characteristics are hypodontia, malformed teeth and underdeveloped alveolar ridges. New alternative treatments are needed due to the failure of the conventional prosthesis retention. This case report outlines the oral rehabilitation treatment of a 9-year-old girl with ectodermal dysplasia. The treatment was performed with conventional prosthesis upon mini-implants. The mini-implants provided prosthetic retention. The patient reported a good adaptation of the dental prosthesis and satisfaction with the treatment. The increased self-esteem improved the socialization skills of the girl. In this case report, use of prosthesis with mini-implants was satisfactory for prosthetic retention. However, clinical studies with long-term follow-up are needed to test the mini-implants as an alternative for oral rehabilitation of children with ectodermal dysplasia.

Automated Mini-Column Solid-Phase Extraction Cleanup for High-Throughput Analysis of Chemical Contaminants in Foods by Low-Pressure Gas Chromatography-Tandem Mass Spectrometry.

PubMed

Lehotay, Steven J; Han, Lijun; Sapozhnikova, Yelena

2016-01-01

This study demonstrated the application of an automated high-throughput mini-cartridge solid-phase extraction (mini-SPE) cleanup for the rapid low-pressure gas chromatography-tandem mass spectrometry (LPGC-MS/MS) analysis of pesticides and environmental contaminants in QuEChERS extracts of foods. Cleanup efficiencies and breakthrough volumes using different mini-SPE sorbents were compared using avocado, salmon, pork loin, and kale as representative matrices. Optimum extract load volume was 300 µL for the 45 mg mini-cartridges containing 20/12/12/1 (w/w/w/w) anh. MgSO 4 /PSA (primary secondary amine)/C 18 /CarbonX sorbents used in the final method. In method validation to demonstrate high-throughput capabilities and performance results, 230 spiked extracts of 10 different foods (apple, kiwi, carrot, kale, orange, black olive, wheat grain, dried basil, pork, and salmon) underwent automated mini-SPE cleanup and analysis over the course of 5 days. In all, 325 analyses for 54 pesticides and 43 environmental contaminants (3 analyzed together) were conducted using the 10 min LPGC-MS/MS method without changing the liner or retuning the instrument. Merely, 1 mg equivalent sample injected achieved <5 ng g -1 limits of quantification. With the use of internal standards, method validation results showed that 91 of the 94 analytes including pairs achieved satisfactory results (70-120 % recovery and RSD ≤ 25 %) in the 10 tested food matrices ( n  = 160). Matrix effects were typically less than ±20 %, mainly due to the use of analyte protectants, and minimal human review of software data processing was needed due to summation function integration of analyte peaks. This study demonstrated that the automated mini-SPE + LPGC-MS/MS method yielded accurate results in rugged, high-throughput operations with minimal labor and data review.

Mini-tablets versus pellets as promising multiparticulate modified release delivery systems for highly soluble drugs.

PubMed

Gaber, Dina M; Nafee, Noha; Abdallah, Osama Y

2015-07-05

Whether mini-tablets (tablets, diameters ≤6mm) belong to single- or multiple-unit dosage forms is still questionable. Accordingly, Pharmacopoeial evaluation procedures for mini-tablets are lacking. In this study, the aforementioned points were discussed. Moreover, their potential for oral controlled delivery was assessed. The antidepressant venlafaxine hydrochloride (Vx), a highly soluble drug undergoing first pass effect, low bioavailability and short half-life was selected as a challenging payload. In an attempt to weigh up mini-tablets versus pellets as multiparticulate carriers, Vx-loaded mini-tablets were compared to formulated pellets of the same composition and the innovator Effexor(®)XR pellets. Formulations were prepared using various polymer hydrogels in the core and ethyl cellulose film coating with increasing thickness. Mini-tablets (diameter 2mm) showed extended Vx release (<60%, 8h). Indeed, release profiles comparable to Effexor(®)XR pellets were obtained. Remarkably higher coating thickness was required for pellets to provide equivalent retardation. Ethyl cellulose in the core ensured faster release due to polymer migration to the surface and pore formation in the coat. mini-tablets showed higher stability to pellets upon storage. Industrially speaking, mini-tablets proved to be superior to pellets in terms of manufacturing, product quality and economical aspects. Results point out the urgent need for standardized evaluation procedures for mini-tablets. Copyright © 2015. Published by Elsevier B.V.

Seed Embryo Development Is Regulated via an AN3-MINI3 Gene Cascade

PubMed Central

Meng, Lai-Sheng; Wang, Yi-Bo; Loake, Gary J.; Jiang, Ji-Hong

2016-01-01

In agriculture, seed mass is one of the most important components related to seed yield. MINISEED3 (MINI3) which encodes the transcriptional activator WRKY10, is thought to be a pivotal regulator of seed mass. In Arabidopsis SHORT HYPOCOTYL UNDER BLUE1 (SHB1) associates with the promoter of MINI3, regulating embryo cell proliferation (both cell division and elongation), which, in turn, modulates seed mass. Furthermore, the recruitment of SHB1 via MINI3 to both its cognate promoter and that of IKU2 implies a two-step amplification for countering the low expression level of IKU2, which is thought to function as a molecular switch for seed cavity enlargement. However, it is largely unknown how embryo cell proliferation, which encompasses both cell division and elongation, is regulated by SHB1 and MINI3 function. Here, we show that a loss of function mutation within the transcriptional coactivator ANGUSTIFOLIA3 (AN3), increases seed mass. Further, AN3 associates with the MINI3 promoter in vivo. Genetic evidence indicates that the absence of MINI3 function suppresses the decrease of cell number observed in an3-4 mutants by regulating cell division and in turn inhibits increased cell size of the an3-4 line by controlling cell elongation. Thus, seed embryo development is modulated via an AN3-MINI3 gene cascade. This regulatory model provides a deeper understanding of seed mass regulation, which may in turn lead to increased crop yields. PMID:27857719

Arabidopsis Chloroplast Mini-Ribonuclease III Participates in rRNA Maturation and Intron Recycling

PubMed Central

Hotto, Amber M.; Castandet, Benoît; Gilet, Laetitia; Higdon, Andrea; Condon, Ciarán; Stern, David B.

2015-01-01

RNase III proteins recognize double-stranded RNA structures and catalyze endoribonucleolytic cleavages that often regulate gene expression. Here, we characterize the functions of RNC3 and RNC4, two Arabidopsis thaliana chloroplast Mini-RNase III-like enzymes sharing 75% amino acid sequence identity. Whereas rnc3 and rnc4 null mutants have no visible phenotype, rnc3/rnc4 (rnc3/4) double mutants are slightly smaller and chlorotic compared with the wild type. In Bacillus subtilis, the RNase Mini-III is integral to 23S rRNA maturation. In Arabidopsis, we observed imprecise maturation of 23S rRNA in the rnc3/4 double mutant, suggesting that exoribonucleases generated staggered ends in the absence of specific Mini-III-catalyzed cleavages. A similar phenotype was found at the 3′ end of the 16S rRNA, and the primary 4.5S rRNA transcript contained 3′ extensions, suggesting that Mini-III catalyzes several processing events of the polycistronic rRNA precursor. The rnc3/4 mutant showed overaccumulation of a noncoding RNA complementary to the 4.5S-5S rRNA intergenic region, and its presence correlated with that of the extended 4.5S rRNA precursor. Finally, we found rnc3/4-specific intron degradation intermediates that are probable substrates for Mini-III and show that B. subtilis Mini-III is also involved in intron regulation. Overall, this study extends our knowledge of the key role of Mini-III in intron and noncoding RNA regulation and provides important insight into plastid rRNA maturation. PMID:25724636

Peak insertion torque values of five mini-implant systems under different insertion loads.

PubMed

Quraishi, Erma; Sherriff, Martyn; Bister, Dirk

2014-06-01

To assess the effect of 1 and 3 kg insertion load on five makes of self-drilling mini-implants on peak insertion torque values to establish risk factors involved in the fracture of mini-implants. Two different loads were applied during insertion of 40 mini-implants from five different manufacturers (Dual Top(™) (1·6×8 mm), Infinitas(™) (1·5×9 mm), Ortho Easy(™) (1·7×8 mm), Spider Screw(™) (1·5×8 mm) and Vector TAS(™) (1·4×8 mm)) into acrylic blocks at 8 rev/min utilizing a Motorized Torque Measurement Stand. Peak insertion torque values for both loads were highest for Vector TAS followed by Ortho Easy and Dual Top and were nearly three times higher than Infinitas (original version) and Spider Screws(TM). The log-rank test showed statistically significant differences for both loads for Vector TAS, Ortho Easy and Spider Screws. Unlike other designs tested, both tapered mini-implant designs (Spider Screw and Infinitas) showed a tendency to buckle in the middle of the body but fractured at the tip. Non-tapered mini-implants fractured at significantly higher torque values compared to tapered designs under both loads. Increased pressure resulted in slightly higher maximum torque values at fracture for some of the mini-implant designs, although this is unlikely to be of clinical relevance. Tripling insertion pressure from 1 to 3 kg increased the risk of bending tapered mini-implants before fracture. © 2014 British Orthodontic Society.

Stacked, filtered multi-channel X-ray diode array

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacNeil, Lawrence; Dutra, Eric; Raphaelian, Mark

2015-08-01

There are many types of X-ray diodes used for X-ray flux or spectroscopic measurements and for estimating the spectral shape of the VUV to soft X-ray spectrum. However, a need exists for a low-cost, robust X-ray diode to use for experiments in hostile environments on multiple platforms, and for experiments that utilize forces that may destroy the diode(s). Since the typical proposed use required a small size with a minimal single line-of-sight, a parallel array could not be used. So, a stacked, filtered multi-channel X-ray diode array was developed, called the MiniXRD. To achieve significant cost savings while maintaining robustnessmore » and ease of field setup, repair, and replacement, we designed the system to be modular. The filters were manufactured in-house and cover the range from 450 eV to 5000 eV. To achieve the line-of-sight accuracy needed, we developed mounts and laser alignment techniques. We modeled and tested elements of the diode design at NSTec Livermore Operations (NSTec / LO) to determine temporal response and dynamic range, leading to diode shape and circuitry changes to optimize impedance and charge storage. The authors fielded individual and stacked systems at several national facilities as ancillary "ride-along" diagnostics to test and improve the design usability. This paper presents the MiniXRD system performance, which supports consideration as a viable low-costalternative for multiple-channel low-energy X-ray measurements. This diode array is currently at Technical Readiness Level (TRL) 6.« less

Eigensystem realization algorithm modal identification experiences with mini-mast

NASA Technical Reports Server (NTRS)

Pappa, Richard S.; Schenk, Axel; Noll, Christopher

1992-01-01

This paper summarizes work performed under a collaborative research effort between the National Aeronautics and Space Administration (NASA) and the German Aerospace Research Establishment (DLR, Deutsche Forschungsanstalt fur Luft- und Raumfahrt). The objective is to develop and demonstrate system identification technology for future large space structures. Recent experiences using the Eigensystem Realization Algorithm (ERA), for modal identification of Mini-Mast, are reported. Mini-Mast is a 20 m long deployable space truss used for structural dynamics and active vibration-control research at the Langley Research Center. A comprehensive analysis of 306 frequency response functions (3 excitation forces and 102 displacement responses) was performed. Emphasis is placed on two topics of current research: (1) gaining an improved understanding of ERA performance characteristics (theory vs. practice); and (2) developing reliable techniques to improve identification results for complex experimental data. Because of nonlinearities and numerous local modes, modal identification of Mini-Mast proved to be surprisingly difficult. Methods were available, ERA, for obtaining detailed, high-confidence results.

[Application of mini-septopal in surgery of the hand].

PubMed

Zimmer, K

1992-01-01

Successful application of the Septopal in treatment of osteomyelitis has created the demand for this form of drug available for implantation into the small operation field, e.c. in the hand. The Chair and Clinic for Traumatology of the Medical Academy in Wrocław has been chosen to cooperate in the clinical trial on application of the Septopal-minichains in surgery of hand. There were 76 patients treated with the Mini-Septopal implantation. In 18 cases the osteomyelitis or active bacterial soft tissue infection gave indications for this type of treatment. In 58 cases Mini-Septopal was implanted because of high risk of infection in contaminated wounds. In both groups bacteriological examinations have been performed and statistical study revealed successful results even in primary resistant for gentamicin bacteries. Very good results of treatment let us estimate very high the usefulness of Mini-Septopal in bone and soft-tissue infections treatment, if the proper surgical procedures are performed to clean the focus of infection.

Synthesis, structural characterization and biological activity of two diastereomeric JA-Ile macrolactones.

PubMed

Jimenez-Aleman, Guillermo H; Machado, Ricardo A R; Görls, Helmar; Baldwin, Ian T; Boland, Wilhelm

2015-06-07

Jasmonates are phytohormones involved in a wide range of plant processes, including growth, development, senescence, and defense. Jasmonoyl-L-isoleucine (JA-Ile, 2), an amino acid conjugate of jasmonic acid (JA, 1), has been identified as a bioactive endogenous jasmonate. However, JA-Ile (2) analogues trigger different responses in the plant. ω-Hydroxylation of the pentenyl side chain leads to the inactive 12-OH-JA-Ile (3) acting as a “stop” signal. On the other hand, a lactone derivative of 12-OH-JA (5) (jasmine ketolactone, JKL) occurs in nature, although with no known biological function. Inspired by the chemical structure of JKL (6) and in order to further explore the potential biological activities of 12-modified JA-Ile derivatives, we synthesized two macrolactones (JA-Ile-lactones (4a) and (4b)) derived from 12-OH-JA-Ile (3). The biological activity of (4a) and (4b) was tested for their ability to elicit nicotine production, a well-known jasmonate dependent secondary metabolite. Both macrolactones showed strong biological activity, inducing nicotine accumulation to a similar extent as methyl jasmonate does in Nicotiana attenuata leaves. Surprisingly, the highest nicotine contents were found in plants treated with the JA-Ile-lactone (4b), which has (3S,7S) configuration at the cyclopentanone not known from natural jasmonates. Macrolactone (4a) is a valuable standard to explore for its occurrence in nature.

Characteristics of Mini-Magnetospheres Formed by Paleo-Magnetic Fields of Mars

NASA Technical Reports Server (NTRS)

Ness, N. F.; Krymskii, A. M.; Crider, D. H.; Breus, T. K.; Acuna, M. H.; Hinson, D.; Barashyan, K. K.

2003-01-01

The intensely and non-uniformly magnetized crustal sources generate an effective large-scale magnetic field. In the Southern hemisphere the strongest crustal fields lead to the formation of large-scale mini-magnetospheres. In the Northern hemisphere, the crustal fields are rather weak and there are only isolated mini-magnetospheres. Re-connection with the interplanetary magnetic field (IMF) occurs in many localized regions. This may occur not only in cusp-like structures above nearly vertical field anomalies but also in halos extending several hundreds of kilometers from these sources. Re-connection will permit solar wind (SW) and more energetic particles to precipitate into and heat the neutral atmosphere. Electron density profiles of the ionosphere of Mars derived from radio occultation data obtained by the Radio Science Mars Global Surveyor (MGS) experiment are concentrated in the near polar regions. The effective scale-height of the neutral atmosphere density in the vicinity of the ionization peak has been derived for each of the profiles studied. The effective scale-heights have been compared with the crustal magnetic fields measured by the MGS Magnetometer/Electron Reflectometer (MAG/ER) experiment. A significant difference between the large-scale mini-magnetospheres and regions outside of them has been found. The neutral atmosphere is cooler inside the large-scale mini-magnetospheres. It appears that outside of the cusps the strong crustal magnetic fields prevent additional heating of the neutral atmosphere by direct interaction of the SW. The scale-height of the neutral atmosphere density derived from the experiment with the MGS Accelerometer has been compared with MAG/ER data. The scale-height was found to be usually larger than mean value near the boundaries of potential mini-magnetospheres and around cusps . It may indicate that the paleo-magnetic/IMF field re-connection is characteristic of the mini-magnetospheres at Mars.

LED mini-lidar as minimum setup

NASA Astrophysics Data System (ADS)

Shiina, Tatsuo

2014-10-01

The LED mini-lidar has been designed and demonstrated as the near range atmosphere monitoring, dust and gas detections. The LED lamp is used as a lidar light source. It is not a special one, and just used as a small status indicator or a spot luminaire. For the atmospheric monitoring in the near range of a few hundreds meters, the energy of 1nJ (=100mW/10ns) is enough for lidar observation in the nighttime. The LED lamp is excited at the high repetition frequency of < 1MHz. The signal-to-noise ratio can be increased by this high frequency even if the receiving photons are a little at each pulse. It is adequate because the spatiotemporal scale of the low-altitude atmosphere is small of a ten seconds and a few tens meters. To pursue such quick motion of the atmosphere and dust, the high-speed photon counter has been developed. It can act with BIN width of 4ns (Spatial resolution 0.6m) at the repetition frequency of <500kHz. The LED mini-lidar has been demonstrated to monitor the actual atmosphere of the observation range of <500m in the nighttime and <100m in the daytime with the receiving lens of 200mmφ. The interest approach is tired to distinguish the dust characteristics by using the counting rate of dust echoes. It is effective in the case that the dust material is given. And for trial, the LED mini-Raman-lidar is developed to monitor certain gas detection in near distance, too.

Mini-Lectures: A Taster to Engage the Audience for the Main Event

ERIC Educational Resources Information Center

Ingram, Matthew J.; Crane, Simeon; Mokree, Alan; Curdy, Marion E.; Patel, Bhavik A.

2017-01-01

This article explores the use of pre-recorded video mini-lectures to support and enhance traditional face-to-face lectures for undergraduate students. Mini-lectures guide students through key concepts so that they can understand and assimilate key content before attending lectures.

Endogenous Bioactive Jasmonate Is Composed of a Set of (+)-7-iso-JA-Amino Acid Conjugates1

PubMed Central

Li, Suhua; Li, Yuwen; Chen, Juan; Yang, Mai; Tong, Jianhua; Xiao, Langtao; Nan, Fajun; Xie, Daoxin

2016-01-01

Jasmonates (JAs) regulate a wide range of plant defense and development processes. The bioactive JA is perceived by its receptor COI1 to trigger the degradation of JASMONATE ZIM-DOMAIN (JAZ) proteins and subsequently derepress the JAZ-repressed transcription factors for activation of expression of JA-responsive genes. So far, (+)-7-iso-JA-l-Ile has been the only identified endogenous bioactive JA molecule. Here, we designed coronafacic acid (CFA) conjugates with all the amino acids (CFA-AA) to mimic the JA amino acid conjugates, and revealed that (+)-7-iso-JA-Leu, (+)-7-iso-JA-Val, (+)-7-iso-JA-Met, and (+)-7-iso-JA-Ala are new endogenous bioactive JA molecules. Furthermore, our studies uncover the general characteristics for all the bioactive JA molecules, and provide a new strategy to synthetically generate novel active JA molecules. PMID:27756820

A regulatory toolbox of MiniPromoters to drive selective expression in the brain

PubMed Central

Portales-Casamar, Elodie; Swanson, Douglas J.; Liu, Li; de Leeuw, Charles N.; Banks, Kathleen G.; Ho Sui, Shannan J.; Fulton, Debra L.; Ali, Johar; Amirabbasi, Mahsa; Arenillas, David J.; Babyak, Nazar; Black, Sonia F.; Bonaguro, Russell J.; Brauer, Erich; Candido, Tara R.; Castellarin, Mauro; Chen, Jing; Chen, Ying; Cheng, Jason C. Y.; Chopra, Vik; Docking, T. Roderick; Dreolini, Lisa; D'Souza, Cletus A.; Flynn, Erin K.; Glenn, Randy; Hatakka, Kristi; Hearty, Taryn G.; Imanian, Behzad; Jiang, Steven; Khorasan-zadeh, Shadi; Komljenovic, Ivana; Laprise, Stéphanie; Liao, Nancy Y.; Lim, Jonathan S.; Lithwick, Stuart; Liu, Flora; Liu, Jun; Lu, Meifen; McConechy, Melissa; McLeod, Andrea J.; Milisavljevic, Marko; Mis, Jacek; O'Connor, Katie; Palma, Betty; Palmquist, Diana L.; Schmouth, Jean-François; Swanson, Magdalena I.; Tam, Bonny; Ticoll, Amy; Turner, Jenna L.; Varhol, Richard; Vermeulen, Jenny; Watkins, Russell F.; Wilson, Gary; Wong, Bibiana K. Y.; Wong, Siaw H.; Wong, Tony Y. T.; Yang, George S.; Ypsilanti, Athena R.; Jones, Steven J. M.; Holt, Robert A.; Goldowitz, Daniel; Wasserman, Wyeth W.; Simpson, Elizabeth M.

2010-01-01

The Pleiades Promoter Project integrates genomewide bioinformatics with large-scale knockin mouse production and histological examination of expression patterns to develop MiniPromoters and related tools designed to study and treat the brain by directed gene expression. Genes with brain expression patterns of interest are subjected to bioinformatic analysis to delineate candidate regulatory regions, which are then incorporated into a panel of compact human MiniPromoters to drive expression to brain regions and cell types of interest. Using single-copy, homologous-recombination “knockins” in embryonic stem cells, each MiniPromoter reporter is integrated immediately 5′ of the Hprt locus in the mouse genome. MiniPromoter expression profiles are characterized in differentiation assays of the transgenic cells or in mouse brains following transgenic mouse production. Histological examination of adult brains, eyes, and spinal cords for reporter gene activity is coupled to costaining with cell-type–specific markers to define expression. The publicly available Pleiades MiniPromoter Project is a key resource to facilitate research on brain development and therapies. PMID:20807748

A regulatory toolbox of MiniPromoters to drive selective expression in the brain.

PubMed

Portales-Casamar, Elodie; Swanson, Douglas J; Liu, Li; de Leeuw, Charles N; Banks, Kathleen G; Ho Sui, Shannan J; Fulton, Debra L; Ali, Johar; Amirabbasi, Mahsa; Arenillas, David J; Babyak, Nazar; Black, Sonia F; Bonaguro, Russell J; Brauer, Erich; Candido, Tara R; Castellarin, Mauro; Chen, Jing; Chen, Ying; Cheng, Jason C Y; Chopra, Vik; Docking, T Roderick; Dreolini, Lisa; D'Souza, Cletus A; Flynn, Erin K; Glenn, Randy; Hatakka, Kristi; Hearty, Taryn G; Imanian, Behzad; Jiang, Steven; Khorasan-zadeh, Shadi; Komljenovic, Ivana; Laprise, Stéphanie; Liao, Nancy Y; Lim, Jonathan S; Lithwick, Stuart; Liu, Flora; Liu, Jun; Lu, Meifen; McConechy, Melissa; McLeod, Andrea J; Milisavljevic, Marko; Mis, Jacek; O'Connor, Katie; Palma, Betty; Palmquist, Diana L; Schmouth, Jean-François; Swanson, Magdalena I; Tam, Bonny; Ticoll, Amy; Turner, Jenna L; Varhol, Richard; Vermeulen, Jenny; Watkins, Russell F; Wilson, Gary; Wong, Bibiana K Y; Wong, Siaw H; Wong, Tony Y T; Yang, George S; Ypsilanti, Athena R; Jones, Steven J M; Holt, Robert A; Goldowitz, Daniel; Wasserman, Wyeth W; Simpson, Elizabeth M

2010-09-21

The Pleiades Promoter Project integrates genomewide bioinformatics with large-scale knockin mouse production and histological examination of expression patterns to develop MiniPromoters and related tools designed to study and treat the brain by directed gene expression. Genes with brain expression patterns of interest are subjected to bioinformatic analysis to delineate candidate regulatory regions, which are then incorporated into a panel of compact human MiniPromoters to drive expression to brain regions and cell types of interest. Using single-copy, homologous-recombination "knockins" in embryonic stem cells, each MiniPromoter reporter is integrated immediately 5' of the Hprt locus in the mouse genome. MiniPromoter expression profiles are characterized in differentiation assays of the transgenic cells or in mouse brains following transgenic mouse production. Histological examination of adult brains, eyes, and spinal cords for reporter gene activity is coupled to costaining with cell-type-specific markers to define expression. The publicly available Pleiades MiniPromoter Project is a key resource to facilitate research on brain development and therapies.

ShellFit: Reconstruction in the MiniCLEAN Detector

NASA Astrophysics Data System (ADS)

Seibert, Stanley

2010-02-01

The MiniCLEAN dark matter experiment is an ultra-low background liquid cryogen detector with a fiducial volume of approximately 150 kg. Dark matter candidate events produce ultraviolet scintillation light in argon at 128 nm and in neon at 80 nm. In order to detect this scintillation light, the target volume is enclosed by acrylic plates forming a spherical shell upon which an organic fluor, tetraphenyl butadiene (TPB), has been applied. TPB absorbs UV light and reemits visible light isotropically which can be detected by photomultiplier tubes. Two significant sources of background events in MiniCLEAN are decays of radon daughters embedded in the acrylic surface and external sources of neutrons, such as the photomultiplier tubes themselves. Both of these backgrounds can be mitigated by reconstructing the origin of the scintillation light and cutting events beyond a particular radius. The scrambling of photon trajectories at the TPB surface makes this task very challenging. The ``ShellFit'' algorithm for reconstructing event position and energy in a detector with a spherical wavelength-shifting shell will be described. The performance of ShellFit will be demonstrated using Monte Carlo simulation of several event types in the MiniCLEAN detector. )

Identification of processed Chinese medicinal materials using DNA mini-barcoding.

PubMed

Song, Ming; Dong, Gang-Qiang; Zhang, Ya-Qin; Liu, Xia; Sun, Wei

2017-07-01

Most of Chinese medicinal herbs are subjected to traditional processing procedures, including stir-frying, charring, steaming, boiling, and calcining before they are released into dispensaries. The marketing and identification of processed medicinal materials is a growing issue in the marketplace. However, conventional methods of identification have limitations, while DNA mini-barcoding, based on the sequencing of a short-standardized region, has received considerable attention as a new potential means to identify processed medicinal materials. In the present study, six DNA barcode loci including ITS2, psbA-trnH, rbcL, matK, trnL (UAA) intron and its P6 loop, were employed for the authentication of 45 processed samples belonging to 15 species. We evaluated the amplification efficiency of each locus. We also examined the identification accuracy of the potential mini-barcode locus, of trnL (UAA) intron P6 loop. Our results showed that the five primary barcode loci were successfully amplified in only 8.89%-20% of the processed samples, while the amplification rates of the trnL (UAA) intron P6 loop were higher, at 75.56% successful amplification. We compared the mini-barcode sequences with Genbank using the Blast program. The analysis showed that 45.23% samples could be identified to genus level, while only one sample could be identified to the species level. We conclude that trnL (UAA) p6 loop is a candidate mini-barcode that has shown its potential and may become a universal mini-barcode as complementary barcode for authenticity testing and will play an important role in medicinal materials control. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

Recycling of rare earth particle by mini-hydrocyclones.

PubMed

Yu, Jian-Feng; Fu, Jian; Cheng, Hao; Cui, Zhengwei

2017-03-01

Mini-hydrocyclones were applied to separate the fine rare earth particles from the suspensions. The effects of the flow rate, split ratio, and feed concentration on the total separation efficiency and grade separation efficiency were studied. The combined effects of the flow rate (1200-1600L/h), split ratio (20-60%) and concentration (0.6-1.0wt%) on the total separation efficiency in mini-hydrocyclones were investigated using a response surface methodology. The optimum operating parameters for a total separation efficiency of 92.5% were: feed flow rate=1406L/h, split ratio=20%, and feed concentration=1wt%. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mini AERCam: A Free-Flying Robot for Space Inspection

NASA Technical Reports Server (NTRS)

Fredrickson, Steven

2001-01-01

The NASA Johnson Space Center Engineering Directorate is developing the Autonomous Extravehicular Robotic Camera (AERCam), a free-flying camera system for remote viewing and inspection of human spacecraft. The AERCam project team is currently developing a miniaturized version of AERCam known as Mini AERCam, a spherical nanosatellite 7.5 inches in diameter. Mini AERCam development builds on the success of AERCam Sprint, a 1997 Space Shuttle flight experiment, by integrating new on-board sensing and processing capabilities while simultaneously reducing volume by 80%. Achieving these productivity-enhancing capabilities in a smaller package depends on aggressive component miniaturization. Technology innovations being incorporated include micro electromechanical system (MEMS) gyros, "camera-on-a-chip" CMOS imagers, rechargeable xenon gas propulsion, rechargeable lithium ion battery, custom avionics based on the PowerPC 740 microprocessor, GPS relative navigation, digital radio frequency communications and tracking, micropatch antennas, digital instrumentation, and dense mechanical packaging. The Mini AERCam free-flyer will initially be integrated into an approximate flight-like configuration for laboratory demonstration on an airbearing table. A pilot-in-the-loop and hardware-in-the-loop simulation to simulate on-orbit navigation and dynamics will complement the airbearing table demonstration. The Mini AERCam lab demonstration is intended to form the basis for future development of an AERCam flight system that provides on-orbit views of the Space Shuttle and International Space Station unobtainable from fixed cameras, cameras on robotic manipulators, or cameras carried by space-walking crewmembers.

PVP VA64 as a novel release-modifier for sustained-release mini-matrices prepared via hot melt extrusion.

PubMed

Li, Yongcheng; Lu, Ming; Wu, Chuanbin

2017-11-10

The purpose of this study was to explore poly(vinylpyrrolidone-co-vinyl acetate) (PVP VA64) as a novel release-modifier to tailor the drug release from ethylcellulose (EC)-based mini-matrices prepared via hot melt extrusion (HME). Quetiapine fumarate (QF) was selected as model drug. QF/EC/PVP VA64 mini-matrices were extruded with 30% drug loading. The physical state of QF in extruded mini-matrices was characterized using differential scanning calorimetry, X-ray powder diffraction, and confocal Raman microscopy. The release-controlled ability of PVP VA64 was investigated and compared with that of xanthan gum, crospovidone, and low-substituted hydroxypropylcellulose. The influences of PVP VA64 content and processing temperature on QF release behavior and mechanism were also studied. The results indicated QF dispersed as the crystalline state in all mini-matrices. The release of QF from EC was very slow as only 4% QF was released in 24 h. PVP VA64 exhibited the best ability to enhance the drug release as compared with other three release-modifiers. The drug release increased to 50-100% in 24 h with the addition of 20-40% PVP VA64. Increasing processing temperature slightly slowed down the drug release by decreasing free volume and pore size. The release kinetics showed good fit with the Ritger-Peppas model. The values of release exponent (n) increased as PVP VA64 is added (0.14 for pure EC, 0.41 for 20% PVP VA64, and 0.61 for 40% PVP VA64), revealing that the addition of PVP VA64 enhanced the erosion mechanism. This work presented a new polymer blend system of EC with PVP VA64 for sustained-release prepared via HME.

Poster - 23: Dosimetric Characterization and Transferability of an Accessory Mounted Mini-Beam Collimator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, William; Crewson, Cody; Alexander, Andrew

Objective: The dosimetric characterization of an accessory-mounted mini-beam collimator across three beam matched linear accelerators. Materials and Methods: Percent depth dose and profiles were measured for the open and mini-beam collimated fields. The average beam quality and peak-to-valley dose ratio (PVDR), the ratio of average peak dose to average valley dose, were obtained from these measurements. The open field relative output and the mini-beam collimator factor, the ratio of the mini-beam dose to open field dose at the beam center, were measured for square fields of side 2, 3, 4, and 5 cm. Mini-beam output as a function of collimatormore » inclination angle relative to the central axis was also investigated. Results and Discussion: Beam quality for both the open and mini-beam collimated fields agreed across all linacs to within ±1.0%. The PVDR was found to vary by up to ±6.6% from the mean. For the 2, 3, and 4 cm fields the average open field relative output with respect to the 5 cm field was 0.874±0.4%, 0.921±0.3%, and 0.962±0.1%. The average collimator factors were 0.450±3.9%, 0.443±3.9%, 0.438±3.9%, and 0.434±3.9%. A decrease in collimator factor greater than 7% was found for an inclination angle change of 0.09°. Conclusion: The mini-beam collimator has revealed a difference between the three linacs not apparent in the open field data, yet transferability can still be attained through thorough dosimetric characterization.« less

Magnet-Retained Two-Mini-Implant Overdenture: Clinical and Mechanical Consideration.

PubMed

Ishida, Yuichi; Kumar, H S Kiran; Goto, Takaharu; Watanabe, Megumi; Wigianto, Rudi; Ichikawa, Tetsuo

2016-10-10

Two-implant overdentures have become the accepted treatment for restoring mandibular edentulism. The dimensions of regular implants sometimes limit their use, such as in the case of narrow ridges. Mini-implants with reduced diameters (less than 3.0 mm) enable insertion into narrow ridges. A magnet-retained two-mini-implant overdenture system was developed and is described in this paper. Additionally, we describe a clinical mandibular procedure using the system and evaluate its biomechanical performance.

Sense of Touch

NASA Technical Reports Server (NTRS)

1998-01-01

Logitech Inc., has advanced a digital game controller originally developed for a NASA space mission. CyberMan 2 offers players the experience of being "inside" the game. The product is commercially available for $99 to anyone with a personal computer.

Molecular dynamics simulation of dioxygen pathways through mini singlet oxygen generator (miniSOG), a genetically encoded marker and killer protein.

PubMed

Pietra, Francesco

2014-12-01

In this work, molecular dynamics (MD) simulations of the permeation of proteins by small gases of biological significance have been extended from gas carrier, sensor, and enzymatic proteins to genetically encoded tags and killer proteins. To this end, miniSOG was taken as an example of current high interest, using a biased form of MD, called random-acceleration MD. Various egress gates and binding pockets for dioxygen, as an indistinguishable mimic of singlet dioxygen, were found on both above and below the isoalloxazine plane of the flavin mononucleotide cofactor in miniSOG. Of such gates and binding pockets, those lying within two opposite cones, coaxial with a line normal to the isoalloxazine plane, and with the vertex at the center of such a plane are those most visited by the escaping gas molecule. Out of residues most capable of quenching (1) O2 , Y30, lying near the base of one such a cone, and H85, near the base of the opposite cone, are held to be most responsible for the reduced quantum yield of (1) O2 with folded miniSOG with respect to free flavin mononucleotide in solution. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

Mini-Brayton heat source assembly development

NASA Technical Reports Server (NTRS)

Wein, D.; Zimmerman, W. F.

1978-01-01

The work accomplished on the Mini-Brayton Heat Source Assembly program is summarized. Required technologies to design, fabricate and assemble components for a high temperature Heat Source Assembly (HSA) which would generate and transfer the thermal energy for a spaceborne Brayton Isotope Power System (BIPS) were developed.

Four-stranded mini microtubules formed by Prosthecobacter BtubAB show dynamic instability.

PubMed

Deng, Xian; Fink, Gero; Bharat, Tanmay A M; He, Shaoda; Kureisaite-Ciziene, Danguole; Löwe, Jan

2017-07-18

Microtubules, the dynamic, yet stiff hollow tubes built from αβ-tubulin protein heterodimers, are thought to be present only in eukaryotic cells. Here, we report a 3.6-Å helical reconstruction electron cryomicroscopy structure of four-stranded mini microtubules formed by bacterial tubulin-like Prosthecobacter dejongeii BtubAB proteins. Despite their much smaller diameter, mini microtubules share many key structural features with eukaryotic microtubules, such as an M-loop, alternating subunits, and a seam that breaks overall helical symmetry. Using in vitro total internal reflection fluorescence microscopy, we show that bacterial mini microtubules treadmill and display dynamic instability, another hallmark of eukaryotic microtubules. The third protein in the btub gene cluster, BtubC, previously known as "bacterial kinesin light chain," binds along protofilaments every 8 nm, inhibits BtubAB mini microtubule catastrophe, and increases rescue. Our work reveals that some bacteria contain regulated and dynamic cytomotive microtubule systems that were once thought to be only useful in much larger and sophisticated eukaryotic cells.

Optimising use of the mini C-arm in foot and ankle surgery.

PubMed

Gangopadhyay, Soham; Scammell, Brigitte E

2009-01-01

The mini C-arm reduces exposure to ionising radiation compared to the conventional C-arm. Optimising radiation exposure is not only desirable, but also a legal requirement and protocols should be in place to achieve this. Since 2004, all elective foot surgery requiring intraoperative imaging was performed using the mini C-arm. Screening times and radiation doses were recorded for each procedure. Following a learning curve, the screening times stabilised around the median value for the individual procedures. For subtalar or triple arthrodesis this was less than 60 s, for ankle arthrodesis, less than 90 s, for hindfoot arthrodesis using a nail, less than 100 s and for joint injections less than 12 s. Screening time can be used as an audit tool to measure optimum use of the mini C-arm. A protocol is presented including an audit form for every operation where the mini C-arm is used. Radiation protection issues are addressed.

Prospects for PWNe and SNRs science with the ASTRI mini-array of pre-production small-sized telescopes of the Cherenkov telescope array

NASA Astrophysics Data System (ADS)

Burtovoi, A.; Zampieri, L.; Giuliani, A.; Bigongiari, C.; Di Pierro, F.; Stamerra, A.

2017-01-01

The development and construction of the Cherenkov Telescope Array (CTA) opens up new opportunities for the study of very high energy (VHE, E > 100 GeV) sources. As a part of CTA, the ASTRI project, led by INAF, has one of the main goals to develop one of the mini-arrays of CTA pre-production telescopes, proposed to be installed at the CTA southern site. Thanks to the innovative dual-mirror optical design of its small-sized telescopes, the ASTRI mini-array will be characterized by a large field of view, an excellent angular resolution and a good sensitivity up to energies of several tens of TeV. Pulsar wind nebulae, along with Supernova Remnants, are among the most abundant sources that will be identified and investigated, with the ultimate goal to move significantly closer to an understanding of the origin of cosmic rays (CR). As part of the ongoing effort to investigate the scientific capabilities for both CTA as a whole and the ASTRI mini-array, we performed simulations of the Vela X region. We simulated its extended VHE γ-ray emission using the results of the detailed H.E.S.S. analysis of this source. We estimated the resolving capabilities of the diffuse emission and the detection significance of the pulsar with both CTA as a whole and the ASTRI mini-array. Moreover with these instruments it will be possible to observe the high-energy end of SNRs spectrum, searching for particles with energies near the cosmic-rays "knee" (E ˜ 1015 eV). We simulated a set of ASTRI mini-array observations for one young and an evolved SNRs in order to test the capabilities of this instrument to discover and study PeVatrons on the Galactic plane.

Identification and Analysis of Partial Shading Breakdown Sites in CuIn xGa (1-x)Se 2 Modules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Palmiotti, Elizabeth; Johnston, Steven; Gerber, Andreas

In this paper, CuIn xGa (1-x) (CIGS) mini-modules are stressed under reverse bias, resembling partial shading conditions, to predict and characterize where failures occur. Partial shading can cause permanent damage in the form of 'wormlike' defects on thin-film modules due to thermal runaway. This results in module-scale power losses. We have used dark lock-in thermography (DLIT) to spatially observe localized heating when reverse-bias breakdown occurs on various CIGS mini-modules. For better understanding of how and where these defects originated and propagated, we have developed techniques where the current is limited during reverse-bias stressing. This allows for DLIT-based detection and detailedmore » studying of the region where breakdown is initiated before thermal runaway leads to permanent damage. Statistics of breakdown sites using current-limited conditions has allowed for reasonable identification of the as-grown defects where permanent breakdown will likely originate. Scanning electron microscope results and wormlike defect analysis show that breakdown originates in defects such as small pits, craters, or cracks in the CIGS layer, and the wormlike defects propagate near the top CIGS interface.« less

Identification and Analysis of Partial Shading Breakdown Sites in CuIn xGa (1-x)Se 2 Modules

DOE PAGES

Palmiotti, Elizabeth; Johnston, Steven; Gerber, Andreas; ...

2017-12-20

In this paper, CuIn xGa (1-x) (CIGS) mini-modules are stressed under reverse bias, resembling partial shading conditions, to predict and characterize where failures occur. Partial shading can cause permanent damage in the form of 'wormlike' defects on thin-film modules due to thermal runaway. This results in module-scale power losses. We have used dark lock-in thermography (DLIT) to spatially observe localized heating when reverse-bias breakdown occurs on various CIGS mini-modules. For better understanding of how and where these defects originated and propagated, we have developed techniques where the current is limited during reverse-bias stressing. This allows for DLIT-based detection and detailedmore » studying of the region where breakdown is initiated before thermal runaway leads to permanent damage. Statistics of breakdown sites using current-limited conditions has allowed for reasonable identification of the as-grown defects where permanent breakdown will likely originate. Scanning electron microscope results and wormlike defect analysis show that breakdown originates in defects such as small pits, craters, or cracks in the CIGS layer, and the wormlike defects propagate near the top CIGS interface.« less

New York State Occupational Education Mini-Grant Program. 1972 Final Report.

ERIC Educational Resources Information Center

Alwell, William

The mini-grant concept has emerged in recent years as a specific catalyst for the promotion of educational change. A mini-grant is a small grant awarded to an individual (usually a teacher or supervisor) in order that he might investigate or further develop an idea within the classroom or school setting. Developed in the State of New York, this…

Development of a human rotavirus induced diarrhea model in Chinese mini-pigs.

PubMed

Li, Jin-Tao; Wei, Jing; Guo, Hong-Xia; Han, Jiang-Bo; Ye, Nan; He, Hai-Yang; Yu, Tian-Tian; Wu, Yu-Zhang

2016-08-21

To establish a new animal model for the research of human rotavirus (HRV) infection, its pathogenesis and immunity and evaluation of potential vaccines. 5-d, 30-d and 60-d-old Chinese mini-pigs, Guizhou and Bamma, were inoculated with a single oral dose of attenuated strain Wa, G1, G3 of HRV, and PBS (control), respectively, and fecal samples of pigs from 0 to 7 d post infection (DPI) were collected individually. Enzyme linked immunosorbent assay was used to detect HRV antigen in feces. The HRV was tested by real-time PCR (RT-PCR). The sections of the intestinal tissue were stained with hematoxylin and eosin to observe the morphologic variation by microscopy. Immunofluorescence was used to determine the HRV in intestinal tissue. HRV particles in cells of the ileum were observed by electron micrography. When inoculated with HRV, mini-pigs younger than 30 d developed diarrhea in an age-dependent manner and shed HRV antigen of the same inoculum, as demonstrated by RT-PCR. Histopathological changes were observed in HRV inoculated mini-pigs including small intestinal cell tumefaction and necrosis. HRV that was distributed in the small intestine was restricted to the top part of the villi on the internal wall of the ileum, which was observed by immunofluorescence and transmission electron microscopy. Virus particles were observed in Golgi like follicles in HRV-infected neonatal mini-pigs. Guizhou mini-pigs were more sensitive to HRV than Bamma with respect to RV antigen shedding and clinical diarrhea. These results indicate that we have established a mini-pig model of HRV induced diarrhea. Our findings are useful for the understanding of the pathogenic mechanisms of HRV infection.

Evaluation of mini-implant sites in the posterior maxilla using traditional radiographs and cone-beam computed tomography

PubMed Central

Abbassy, Mona A.; Sabban, Hanady M.; Hassan, Ali H.; Zawawi, Khalid H.

2015-01-01

Objectives: To evaluate the accuracy of using routine 2-dimensional (2D) radiographs (panoramic and periapical) when evaluating the position of orthodontic temporary anchorage devices (mini-implants) in the maxilla, and to compare the results to 3-dimensional cone-beam computed tomography (CBCT). Methods: This cross-sectional study was conducted at King Abdulaziz University, Faculty of Dentistry, Jeddah, Kingdom of Saudi Arabia from February 2014 to January 2015. Panoramic and periapical radiographs were used to examine the position of mini-implants in relation to the adjacent roots. Rating of mini-implants position was performed by 82 dentists from different specialties, using 2 D images according to the following criteria: 1) away from the root; 2) mini-implant tip appears touching the lamina dura; and 3) mini-implant overlays the lamina dura. The results were compared with CBCT findings. Results: There was no difference between dentists from different specialties when rating the position of the mini-implants (Cronbach’s alpha=0.956). The accuracy of the periapical images was 45.1%, while the panoramic images 33.6%. However, both panoramic and periapical radiographs were significantly inaccurate when assessing the mini-implant position when compared with the CBCT findings (p=0.0001). Conclusion: Three-dimensional CBCT technology allows better visualization of mini-implant placement. The use of CBCT when assessing the position of mini-implants is recommended. PMID:26593168

Magnet-Retained Two-Mini-Implant Overdenture: Clinical and Mechanical Consideration

PubMed Central

Ishida, Yuichi; Kumar, H. S. Kiran; Goto, Takaharu; Watanabe, Megumi; Wigianto, Rudi; Ichikawa, Tetsuo

2016-01-01

Two-implant overdentures have become the accepted treatment for restoring mandibular edentulism. The dimensions of regular implants sometimes limit their use, such as in the case of narrow ridges. Mini-implants with reduced diameters (less than 3.0 mm) enable insertion into narrow ridges. A magnet-retained two-mini-implant overdenture system was developed and is described in this paper. Additionally, we describe a clinical mandibular procedure using the system and evaluate its biomechanical performance. PMID:29563477

Validation of an electronic version of the Mini Asthma Quality of Life Questionnaire.

PubMed

Olajos-Clow, J; Minard, J; Szpiro, K; Juniper, E F; Turcotte, S; Jiang, X; Jenkins, B; Lougheed, M D

2010-05-01

The Mini Asthma Quality of Life Questionnaire (MiniAQLQ) is a validated disease-specific quality of life (QOL) paper (p) questionnaire. Electronic (e) versions enable inclusion of asthma QOL in electronic medical records and research databases. To validate an e-version of the MiniAQLQ, compare time required for completion of e- and p-versions, and determine which version participants prefer. Adults with stable asthma were randomized to complete either the e- or p-MiniAQLQ, followed by a 2-h rest period before completing the other version. Agreement between versions was measured using the intraclass correlation coefficient (ICC) and Bland-Altman analysis. Two participants with incomplete p-MiniAQLQ responses were excluded. Forty participants (85% female; age 47.7 +/- 14.9 years; asthma duration 22.6 +/- 16.1 years; FEV(1) 87.1 +/- 21.6% predicted) with both AQLQ scores <6.0 completed the study. Agreement between e- and p-versions for the overall score was acceptable (ICC=0.95) with no bias (difference (Delta) p-e=0.1; P=0.21). ICCs for the symptom, activity limitation, emotional function and environmental stimuli domains were 0.94, 0.89, 0.90, and 0.91 respectively. A small but significant bias (Delta=0.3; P=0.004) was noted in the activity limitation domain. Completion time was significantly longer for the e-version (3.8 +/- 1.9min versus 2.7 +/- 1.1min; P<0.0001). The majority of patients (57.5%) preferred the e-MiniAQLQ; 35% had no preference. This e-version of the MiniAQLQ is valid and was preferred by most participants despite taking slightly longer to complete. Generalizabilty may be limited in younger (12-17) and older (>65) adults.

Evaluation of the success and complication rates of self-drilling orthodontic mini-implants.

PubMed

Gurdan, Z; Szalma, J

2018-05-01

Orthodontic mini-implants are important devices for successful anchorage management in orthodontics; however, the survival of these devices depends on several clinical factors. The aim of our study was to calculate the success and complication rates of orthodontic mini-implants. In this retrospective study, patients of our orthodontic department were enrolled, getting overall 59 orthodontic mini-implants during their orthodontic treatment in a 2-year period. Every patient had one or more of the 1.6 mm × 8 mm in size self-drilling mini-implants (Jeil Dual Top Anchor System, Jeil Medical Corp., Seoul, Korea). Screw loading was performed immediately after insertions, keeping tension forces under 150 g. Soft tissue and bone infections, implant mobility and screw loss, implant fracture, and neighboring tooth injury were registered. Relationships between variables were tested using the Chi-square test for statistical significance. The success rate of the orthodontic mini-implants was 89.8% in this study while the average loading period was 8.1 months. Soft-tissue infections varied between 6.3% and 33.3% of the cases while screw mobility varied between 3.1% and 20.8% of the cases regarding the anatomic localization. Screw mobility was significantly more frequent in the buccal fold than in the palate (P = 0.034). Screw mobility was significantly more frequent in the buccal fold than in the palate (P = 0.034) and screw mobility was found more frequently in case of intrusions than by extrusions (P = 0.036). The overall success rate of mini-implants was found acceptable in this study, however, screw mobility in the buccal fold showed a high incidence, suggesting the thorough consideration of the immediate loading by buccal mini-implants.

Pitfall Traps and Mini-Winkler Extractor as Complementary Methods to Sample Soil Coleoptera.

PubMed

Carneiro, A C; Batistella, D A; Battirola, L D; Marques, M I

2016-02-01

We compared abundance, species richness, and capture efficiency with pitfall traps and mini-Winkler extractors to examine their use as complementary methods for sampling soil Coleoptera during dry (2010) and high water seasons (2011) in three areas, including inundated and non-inundated regions, in the Pantanal of Poconé, Mato Grosso, Brazil. We paired treatments with two 10 × 10 m plots in inundated and non-inundated locations that were repeated three times in each location for a total of 18 plots. In each plot, we used nine pitfall traps and collected 2 m(2) of leaf litter and surface soil samples with mini-Winkler extractors. We collected a total of 4260 adult beetles comprising 36 families, 113 genera, and 505 species. Most were caught in pitfalls (69%) and the remainder in the mini-Winkler extractors (31%). Each method provided distinct information about the beetle community: 252 species were captured only in pitfall traps, 147 using only the mini-Winkler extractors, and these methods shared another 106 species. Pitfall and mini-Winkler contribute in different ways for the sampling of the soil beetle community, and so they should be considered complementary for a more thorough assessment of community diversity.

Quantitative assessment of orthodontic mini-implant displacement: the effect of initial force application.

PubMed

Holst, Alexandra Ioana; Karl, Matthias; Karolczak, Marek; Goellner, Matthias; Holst, Stefan

2010-01-01

Primary stability and micromovement of orthodontic mini-implants depends on a number of factors and influences clinical success or failure. The purpose of this study was to assess the behavior of orthodontic mini-implants upon initial load application. Orthodontic mini-implants (n = 39) were inserted in the alveolar process of maxillary human cadaver specimens (n = 10). Increasing horizontal forces (up to 2.5 N) were applied, and triggered images were taken in 0.5-N load intervals. Additionally, peri-implant parameters based on micro-CT volume data were recorded. Data were subjected to a two-sided nonparametric Wilcoxon signed rank test, and between-group comparisons were assessed with a Mann-Whitney test (alpha = .05). Initial load application led to displacement beyond elastic recovery of the surrounding bone after force release (P < .001). Cortical thickness and insertion depth, despite numeric differences, did not reveal any statistical differences, while displacement of mini-implants was significantly affected by contact to neighboring teeth (P < .001). Insertion technique and initial load application on orthodontic mini-implants may be regarded as two crucial factors for success, while repeated application of orthodontic force does not seem to increase screw mobility.

The development and evaluation of mini-GEMs - short, focused, online e-learning videos in geriatric medicine.

PubMed

Garside, Mark J; Fisher, James M; Blundell, Adrian G; Gordon, Adam L

2018-01-01

Mini Geriatric E-Learning Modules (Mini-GEMs) are short, focused, e-learning videos on geriatric medicine topics, hosted on YouTube, which are targeted at junior doctors working with older people. This study aimed to explore how these resources are accessed and used. The authors analyzed the viewing data from 22 videos published over the first 18 months of the Mini-GEM project. We conducted a focus group of U.K. junior doctors considering their experiences with Mini-GEMS. The Mini-GEMs were viewed 10,291 times over 18 months, equating to 38,435 minutes of total viewing time. The average viewing time for each video was 3.85 minutes. Learners valued the brevity and focused nature of the Mini-GEMs and reported that they watched them in a variety of settings to supplement clinical experiences and consolidate learning. Watching the videos led to an increase in self-reported confidence in managing older patients. Mini-GEMs can effectively disseminate clinical teaching material to a wide audience. The videos are valued by junior doctors due to their accessibility and ease of use.

The Genesis of Creative Greatness: Mini-C and the Expert Performance Approach

ERIC Educational Resources Information Center

Beghetto, Ronald A.; Kaufman, James C.

2007-01-01

The authors' recent theoretical work has focused on developing the construct of mini-c creativity and illustrating how all levels of creative performance follow a trajectory that starts with novel and personally meaningful interpretations (mini-c), which can then progress to intrapersonally judged novel and meaningful contributions (little-c) and…

Extended range of the Lockheed Martin Mini cryocooler

NASA Astrophysics Data System (ADS)

Frank, D.; Sanders, L.; Nason, I.; Mistry, V.; Guzinski, M.; Roth, E.; Olson, J. R.

2017-12-01

This paper describes the expanded performance range of the Lockheed Martin Mini cryocooler thermal mechanical unit (TMU). The design is based on the standard unit originally developed for NASA and a higher capacity developed for ESA. These higher capacity Mini units are in a split configuration with the cold head separated from the compressor. The TMU provides cooling over a wide range of temperatures with a weight of 1.9 kg including the 1.4 kg compressor and the 0.45 kg cold head. The unit provides for 3.5 W cooling at 105 K and approximately 7 W cooling at 150 K for 293 K reject temperature with 60 W of input power.

Mathematics authentic assessment on statistics learning: the case for student mini projects

NASA Astrophysics Data System (ADS)

Fauziah, D.; Mardiyana; Saputro, D. R. S.

2018-03-01

Mathematics authentic assessment is a form of meaningful measurement of student learning outcomes for the sphere of attitude, skill and knowledge in mathematics. The construction of attitude, skill and knowledge achieved through the fulfilment of tasks which involve active and creative role of the students. One type of authentic assessment is student mini projects, started from planning, data collecting, organizing, processing, analysing and presenting the data. The purpose of this research is to learn the process of using authentic assessments on statistics learning which is conducted by teachers and to discuss specifically the use of mini projects to improving students’ learning in the school of Surakarta. This research is an action research, where the data collected through the results of the assessments rubric of student mini projects. The result of data analysis shows that the average score of rubric of student mini projects result is 82 with 96% classical completeness. This study shows that the application of authentic assessment can improve students’ mathematics learning outcomes. Findings showed that teachers and students participate actively during teaching and learning process, both inside and outside of the school. Student mini projects also provide opportunities to interact with other people in the real context while collecting information and giving presentation to the community. Additionally, students are able to exceed more on the process of statistics learning using authentic assessment.

MARGINS mini-lessons: A tour of the Mariana Subduction System (Invited)

NASA Astrophysics Data System (ADS)

Goodliffe, A. M.; Oakley, A.

2009-12-01

MARGINS mini-lessons provide an efficient way to quickly move cutting edge MARGINS research into the university classroom. Instructors who are not necessarily familiar with the MARGINS program can easily use mini-lessons in a variety of educational settings. The mini-lesson described herein is centered on bathymetric and multi-channel seismic data collected during a 2003 NSF-MARGINS funded marine geophysical survey in the Mariana Basin. Designed as an approximately sixty minute lecture segment, the lesson covers both the techniques used to collect marine geophysical data and a description of the geology of the system. All geological provinces are included, from the subducting Pacific Plate in the east to the remnant arc in the west. Representative seismic lines and bathymetric images are presented for each province, along with a description of key processes including deformation of the subducting plate, serpentinite mud volcanism, forearc faulting, potentially tsunamigenic landslides, arc volcanism, and backarc spreading. The Mariana subduction system mini-lesson requires a computer with an internet connection, powerpoint, Google Earth, and a web-browser. Questions are embedded in the powerpoint presentation that can be adapted to a specific interactive response system as needed. Optimally the lesson should be used in parallel with a GeoWall. A 3-dimensional ArcScene visualization of the Mariana system is available for download through the MARGINS mini-lessons web site. Such visualizations are particularly effective in helping students understand complex three-dimensional systems. If presented in a computer lab students will benefit from being able to explore the Mariana system using tools such as GeoMapApp.

Evaluation of cytotoxicity and corrosion resistance of orthodontic mini-implants.

PubMed

Alves, Celha Borges Costa; Segurado, Márcio Nunes; Dorta, Miriam Cristina Leandro; Dias, Fátima Ribeiro; Lenza, Maurício Guilherme; Lenza, Marcos Augusto

2016-01-01

To evaluate and compare in vitro cytotoxicity and corrosion resistance of mini-implants from three different commercial brands used for orthodontic anchorage. Six mini-implants (Conexão(tm), Neodent(tm) and SIN(tm)) were separately immersed in artificial saliva (pH 6.76) for 30 and 60 days. The cytotoxicity of the corrosion extracts was assessed in L929 cell cultures using the violet crystal and MTT assays, as well as cell morphology under light microscopy. Metal surface characteristics before and after immersion in artificial saliva were assessed by means of scanning electron microscopy (SEM). The samples underwent atomic absorption spectrophotometry to determine the concentrations of aluminum and vanadium ions, constituent elements of the alloy that present potential toxicity. For statistical analysis, one-way ANOVA/Bonferroni tests were used for comparisons among groups with p < 0.05 considered significant. Statistical analysis was carried out with Graph Pad PRISM software Version 4.0. No changes in cell viability or morphology were observed. Mini-implants SEM images revealed smooth surfaces with no obvious traces of corrosion. The extracts assessed by means of atomic absorption spectrophotometry presented concentrations of aluminum and vanadium ions below 1.0 µg/mL and 0.5 µg/mL, respectively. Orthodontic mini-implants manufactured by Conexão(tm), Neodent(tm) and SIN(tm) present high corrosion resistance and are not cytotoxic.

Effects of structured written feedback by cards on medical students' performance at Mini Clinical Evaluation Exercise (Mini-CEX) in an outpatient clinic.

PubMed

Haghani, Fariba; Hatef Khorami, Mohammad; Fakhari, Mohammad

2016-07-01

Feedback cards are recommended as a feasible tool for structured written feedback delivery in clinical education while effectiveness of this tool on the medical students' performance is still questionable.  The purpose of this study was to compare the effects of structured written feedback by cards as well as verbal feedback versus verbal feedback alone on the clinical performance of medical students at the Mini Clinical Evaluation Exercise (Mini-CEX) test in an outpatient clinic. This is a quasi-experimental study with pre- and post-test comprising four groups in two terms of medical students' externship. The students' performance was assessed through the Mini-Clinical Evaluation Exercise (Mini-CEX) as a clinical performance evaluation tool. Structured written feedbacks were given to two experimental groups by designed feedback cards as well as verbal feedback, while in the two control groups feedback was delivered verbally as a routine approach in clinical education. By consecutive sampling method, 62 externship students were enrolled in this study and seven students were excluded from the final analysis due to their absence for three days. According to the ANOVA analysis and Post Hoc Tukey test,  no statistically significant difference was observed among the four groups at the pre-test, whereas a statistically significant difference was observed between the experimental and control groups at the post-test  (F = 4.023, p =0.012). The effect size of the structured written feedbacks on clinical performance was 0.19. Structured written feedback by cards could improve the performance of medical students in a statistical sense. Further studies must be conducted in other clinical courses with longer durations.

Biosynthesis of silver and zinc oxide nanoparticles using Pichia fermentans JA2 and their antimicrobial property

NASA Astrophysics Data System (ADS)

Chauhan, Ritika; Reddy, Arpita; Abraham, Jayanthi

2015-01-01

The development of eco-friendly alternative to chemical synthesis of metal nanoparticles is of great challenge among researchers. The present study aimed to investigate the biological synthesis, characterization, antimicrobial study and synergistic effect of silver and zinc oxide nanoparticles against clinical pathogens using Pichia fermentans JA2. The extracellular biosynthesis of silver and zinc oxide nanoparticles was investigated using Pichia fermentans JA2 isolated from spoiled fruit pulp bought in Vellore local market. The crystalline and stable metallic nanoparticles were characterized evolving several analytical techniques including UV-visible spectrophotometer, X-ray diffraction pattern analysis and FE-scanning electron microscope with EDX-analysis. The biosynthesized metallic nanoparticles were tested for their antimicrobial property against medically important Gram positive, Gram negative and fungal pathogenic microorganisms. Furthermore, the biosynthesized nanoparticles were also evaluated for their increased antimicrobial activities with various commercially available antibiotics against clinical pathogens. The biosynthesized silver nanoparticles inhibited most of the Gram negative clinical pathogens, whereas zinc oxide nanoparticles were able to inhibit only Pseudomonas aeruginosa. The combined effect of standard antibiotic disc and biosynthesized metallic nanoparticles enhanced the inhibitory effect against clinical pathogens. The biological synthesis of silver and zinc oxide nanoparticles is a novel and cost-effective approach over harmful chemical synthesis techniques. The metallic nanoparticles synthesized using Pichia fermentans JA2 possess potent inhibitory effect that offers valuable contribution to pharmaceutical associations.

Search for Sterile Neutrinos Using the MiniBooNE Beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sorel, Michel

2005-01-01

The possible existence of light sterile neutrinos in Nature is motivated, and the prospects to extend sterile neutrino searches beyond current limits is substantiated, using the MiniBooNE neutrino beam and detector at Fermilab. We report on the neutrino flux predictions for the MiniBooNE experiment, on the characterization of the charged-current, quasi-elastic interactions of muon neutrinos ({nu}{sub {mu}}n {yields} {mu}{sup -}p) observed, and on the experiment's sensitivity to sterile neutrinos via muon neutrino disappearance.

Use of Orthodontic Mini-Implants for Maxillomandibular Fixation in Mandibular Fracture

PubMed Central

Pires, Mario Sergio Medeiros; Reinhardt, Leandro Calcagno; Antonello, Guilherme de Marco; Torres do Couto, Ricardo

2011-01-01

Orthodontic appliances for skeletal anchorage are becoming increasingly more common in clinical practice. Similarly, different terms such as mini-implants, microimplants, and miniscrews have been used. There is a wide array of appliances currently on the market, in different designs and sizes, diameters, degree of titanium purity, and surface treatment. These appliances have been used for a variety of indications, including tooth retraction, intrusion, and traction. This study aimed to report the clinical case of a 19-year-old patient with a fractured mandible and to propose a novel use of mini-implants: the perioperative placement of mini-implants as anchors for maxillomandibular fixation steel wire ligatures. We concluded that this appliance provides an effective maxillomandibular fixation in patients with mandibular fracture, with little increase in the cost of surgery. PMID:23205173

[Mini-percutaneous nephrolithotomy in the treatment of un-hydronephrotic cata-staghorn renal calculi].

PubMed

Gao, Ning; Chen, He-Qun; Qi, Lin; Yang, Zhong-Qing; Qi, Fan; Zhang, Xiang-Yang

2007-08-01

To evaluate the surgical techniques and clinical effects of mini-percutaneous nephrolithotomy (mini-PCNL) in the treatment of un-hydronephrotic cata-staghorn renal calculi. The clinical data of 46 cases (31 males and 15 females) treated by mini-PCNL were retrospectively analyzed. There were mono-renal calculi in 38 patients (3 patients were the isolated renal calculi) while the other 8 combined opposite side upper urinary tract calculi. The diameter of calculi ranged from 4.2 to 6.4 (mean=5.2) cm. Puncturation was guided by B-type ultrasound. Lithotripsy by air pressure path lithotripter and/or holmium laser was done when the pervium was established. The pervium in the 46 patients was successfully established by one-session puncturation with B-type ultrasonography guidance. The operative time ranged from 140 to 280 (mean=190) min. The amount of blood ranged from 50 to 200 (mean=100) mL and no one needed blood transfusion. Calculus was completely removed in 18 patients (39.1%). Calculi in 10 patients (21.7%) were completely removed among the 20 patients who underwent second-look mini-PCNL. Calculi in 1 of the 3 cases were completely removed by third-look mini-PCNL. Left-over calculi in 17 patients (8 patients after the first time mini-PCNL, 7 patients after second-look, and 2 patients after third-look) were treated by extracorporeal shock-wave lithotripsy (ESWL) and 8 were removed completely. All the 46 patients were followed up for 4 to 48 months. None of them had nephro-hydrops or stenosis. Renal function re-investigation showed that 8 patients recovered and 2 improved in the 10 patients who had azotemia before. Two (5.4%, 2/37) had calculus recurrence in 37 cases which calculi were completely removed before. The size and amount of left-over calculi in 3 patients (33.3%, 3/9) were increasing. Mini-PCNL is effective and causes less trauma for un-hydronephrotic cata-staghorn renal calculi. Mini-PCNL combined ESWL may substitute the open operation and is the

Aspects of alcohol use disorder affecting social cognition as assessed using the Mini Social and Emotional Assessment (mini-SEA).

PubMed

Cox, Sharon; Bertoux, Maxime; Turner, John J D; Moss, Antony; Locker, Kirsty; Riggs, Kevin

2018-06-01

Alcohol Use Disorder (AUD) is associated with problems with processing complex social scenarios. Little is known about the relationship between distinct AUD-related factors (e.g., years of problematic drinking), aspects of cognitive function and dysfunction in individuals diagnosed with AUD, and the relative impact these may have on social cognition. To explore differences in social cognition between a group of participants diagnosed with AUD and controls, using a clinical measure, the Mini Social and Emotional Assessment (mini-SEA). The mini-SEA was used to evaluate social and emotional understanding through a facial emotional recognition task and by utilising a series of social scenes some of which contain a faux pas (social error). Eighty-five participants (individuals with AUD and controls) completed demographic questions and a general cognitive and social cognitive test battery over three consecutive days. Between group analyses revealed that the participants with AUD performed less well on the faux pas test, and differences were also revealed in the emotional facial recognition task. Years of problematic alcohol consumption was the strongest predictor of poor ToM reasoning. These results suggest a strong link between AUD chronicity and social cognition, though the direction of this relationship needs further elucidation. This may be of clinical relevance to abstinence and relapse management, as basic social cognition skills and ability to maintain interpersonal relationships are likely to be crucial to recovery. Copyright © 2018 Elsevier B.V. All rights reserved.

Mini-interfacial fracture toughness as a new validated enamel-bonding effectiveness test.

PubMed

Pongprueksa, Pong; De Munck, Jan; Barreto, Bruno C; Karunratanakul, Kavin; Van Meerbeek, Bart

2016-09-01

Today׳s most commonly applied bonding effectiveness tests are criticized for their high variability and low reliability, the latter in particular with regard to measuring the actual strength of the adhesive interface. in continuation of previous research conducted at dentin, we hereby aimed to validate the novel mini-interfacial fracture toughness (mini-iFT) test on its applicability to assess bonding effectiveness of contemporary adhesives when bonded to enamel. The 3-step etch&rinse (E&R) adhesive OptiBond FL (Kerr), the 2-step self-etch (SE) adhesive Clearfil SE Bond (Kuraray Noritake) and the two multi-mode adhesives Clearfil S(3) Bond Plus (Kuraray Noritake) and Scotchbond Universal (3M ESPE), both used following a 2-step E&R and 1-step SE mode, were applied to clinically relevant, flattened enamel surfaces. A composite (Filtek Z100; 3M ESPE) build-up was made in layers. After 1-week water storage at 37°C, all specimens were sectioned perpendicular to the interface to obtain rectangular sticks. A mini-iFT notch was prepared at the adhesive-enamel interface using a thin diamond blade under water cooling. Finally, the specimens were loaded in a 4-point bending test until failure. the mini-iFT onto human enamel was significantly higher for the adhesives applied in E&R mode versus those applied in SE mode. The lowest mini-iFT was found for the adhesives applied following a 1-step SE approach. SEM fracture analysis revealed that all fractures originated at the adhesive-enamel interface and that the induced crack propagated preferentially along this interface. mini-iFT appeared a valid alternative method to assess the mechanical properties of adhesive-enamel interfaces. Copyright © 2016 Elsevier Ltd. All rights reserved.

Design considerations, architecture, and use of the Mini-Sentinel distributed data system.

PubMed

Curtis, Lesley H; Weiner, Mark G; Boudreau, Denise M; Cooper, William O; Daniel, Gregory W; Nair, Vinit P; Raebel, Marsha A; Beaulieu, Nicolas U; Rosofsky, Robert; Woodworth, Tiffany S; Brown, Jeffrey S

2012-01-01

We describe the design, implementation, and use of a large, multiorganizational distributed database developed to support the Mini-Sentinel Pilot Program of the US Food and Drug Administration (FDA). As envisioned by the US FDA, this implementation will inform and facilitate the development of an active surveillance system for monitoring the safety of medical products (drugs, biologics, and devices) in the USA. A common data model was designed to address the priorities of the Mini-Sentinel Pilot and to leverage the experience and data of participating organizations and data partners. A review of existing common data models informed the process. Each participating organization designed a process to extract, transform, and load its source data, applying the common data model to create the Mini-Sentinel Distributed Database. Transformed data were characterized and evaluated using a series of programs developed centrally and executed locally by participating organizations. A secure communications portal was designed to facilitate queries of the Mini-Sentinel Distributed Database and transfer of confidential data, analytic tools were developed to facilitate rapid response to common questions, and distributed querying software was implemented to facilitate rapid querying of summary data. As of July 2011, information on 99,260,976 health plan members was included in the Mini-Sentinel Distributed Database. The database includes 316,009,067 person-years of observation time, with members contributing, on average, 27.0 months of observation time. All data partners have successfully executed distributed code and returned findings to the Mini-Sentinel Operations Center. This work demonstrates the feasibility of building a large, multiorganizational distributed data system in which organizations retain possession of their data that are used in an active surveillance system. Copyright © 2012 John Wiley & Sons, Ltd.

Evaluation of X-38 Crew Return Vehicle Input Control Devices in a Microgravity Environment

NASA Technical Reports Server (NTRS)

Welge, Kirsten; Moore, Alicia; Pope, Ruth Ann; Shivers, Suzette; Fox, Jeffrey

2000-01-01

This report was created by students from Longview High School, Longview, Texas. Longview High School was selected from a group of Texas high schools to participate in the 1999 Texas Fly High Program. This program gives Texas high school students a chance to work with NASA engineers to design and fly a real-world experiment aboard the KC-135 during zero-g parabolas. Jeffrey Fox's role was to provide a concept for the experiment and to mentor the students in its design and testing. The students were responsible for executing all phases of the project. The X-38 Project Office at the Lyndon B. Johnson Space Center Johnson Space is designing a crew return vehicle (CRV) to be docked at the International Space Station for crew rescue in an emergency. Vehicle controls will be almost completely automated, but a few functions will be manually controlled. Four crew input control devices were selected for evaluation by Longview High School students as part of the 1999 Texas Fly High program. These were (1) Logitech Trackman Marble (optical trackball), (2) Smart Cat Touchpad. (3) Microsoft SideWinder 3D-Pro Joystick, and (4) Microsoft SideWinder Gamepad. In two flight tests in the KC-135 aircraft and a series of ground tests, the devices were evaluated for ability to maneuver an on-screen cursor, level of accuracy, ease of handling blind operations, and level of user comfort in microgravity. The tests results led to recommendation of further tests with the Joystick and the Trackman by astronauts and actual space station residents.

Mini-Versus Traditional: An Experimental Study of High School Social Studies Curricula.

ERIC Educational Resources Information Center

Roberts, Arthur D.; Gable, Robert K.

This study assessed some of the cognitive and affective elements for both the traditional and mini curricula. The hypothesis, stated in the null form, was there will be no difference between students in the mini-course curriculum and the traditional curriculum on a number of stated cognitive variables (focusing on critical thinking and reading…

Using Junior Achievement as a Vocational Option for Youth with Special Needs.

ERIC Educational Resources Information Center

Schoff, Patty

Junior Achievement (JA) offers high school students its traditional evening program, in which business advisors help students run their own mini-businesses. In 1980, JA offered this program to mentally, emotionally, and physically disabled students aged 16-21. The special needs component operates an in-class program where students run companies…

MiniWall Tool for Analyzing CFD and Wind Tunnel Large Data Sets

NASA Technical Reports Server (NTRS)

Schuh, Michael J.; Melton, John E.; Stremel, Paul M.

2017-01-01

It is challenging to review and assimilate large data sets created by Computational Fluid Dynamics (CFD) simulations and wind tunnel tests. Over the past 10 years, NASA Ames Research Center has developed and refined a software tool dubbed the MiniWall to increase productivity in reviewing and understanding large CFD-generated data sets. Under the recent NASA ERA project, the application of the tool expanded to enable rapid comparison of experimental and computational data. The MiniWall software is browser based so that it runs on any computer or device that can display a web page. It can also be used remotely and securely by using web server software such as the Apache HTTP server. The MiniWall software has recently been rewritten and enhanced to make it even easier for analysts to review large data sets and extract knowledge and understanding from these data sets. This paper describes the MiniWall software and demonstrates how the different features are used to review and assimilate large data sets.

MiniWall Tool for Analyzing CFD and Wind Tunnel Large Data Sets

NASA Technical Reports Server (NTRS)

Schuh, Michael J.; Melton, John E.; Stremel, Paul M.

2017-01-01

It is challenging to review and assimilate large data sets created by Computational Fluid Dynamics (CFD) simulations and wind tunnel tests. Over the past 10 years, NASA Ames Research Center has developed and refined a software tool dubbed the "MiniWall" to increase productivity in reviewing and understanding large CFD-generated data sets. Under the recent NASA ERA project, the application of the tool expanded to enable rapid comparison of experimental and computational data. The MiniWall software is browser based so that it runs on any computer or device that can display a web page. It can also be used remotely and securely by using web server software such as the Apache HTTP Server. The MiniWall software has recently been rewritten and enhanced to make it even easier for analysts to review large data sets and extract knowledge and understanding from these data sets. This paper describes the MiniWall software and demonstrates how the different features are used to review and assimilate large data sets.

Mirror Technology Development for The International X-Ray Observatory Mission

NASA Technical Reports Server (NTRS)

Zhang, Will

2010-01-01

Presentation slides include: International X-ray Observatory (IXO), Lightweight and High Resolution X-ray Optics is Needed; Modular Design of Mirror Assembly, IXO Mirror Technology Development Objectives, Focus of Technology Development, Slumping - Status, Mirror Fabrication Progress, Temporary Bonding - Status, Alignment - Status, Permanent Bonding - Status, Mirror Housing Simulator (MHS) - TRL-4, Mini-Module (TRL-5), Flight-Like Module (TRL-6), Mirror Technology Development Team, Outlook, and Small Technology Firms that Have Made Direct Contributions to IXO Mirror Technology Development.

Lateral forces exerted through ball or bar attachments in relation to the inclination of mini-implant underneath overdentures: in vitro study.

PubMed

Takagaki, Kyozo; Gonda, Tomoya; Maeda, Yoshinobu

2015-09-01

Lateral force to mini-implants should be avoided because mini-implants are weak mechanically because of its small diameter. Overdentures retained by mini-implants are usually formed using ball attachments. However, bar attachments can offer the advantage of splinting the mini-implants. This study examined the effect of attachments in withstanding these lateral forces in tilted mini-implants of overdentures. Strain gauges were attached to the mini-implants (2.5 × 18 mm) embedded in an acrylic resin block. Two mini-implants were inserted vertically (Control) or with one mini-implant inclined at 10° or 20° (10-inclined and 20-inclined, respectively). The female portions of the attachments were secured to the denture base. A prefabricated ball attachment and CAD/CAM-fabricated bar attachment were compared. A vertical load of 49 N was applied to the occlusal surface at a distance 10 mm away from the center of two mini-implants. The lateral force borne by the mini-implants was measured via the attached strain gauge. Mann-Whitney U-test and an analysis of Bonferroni correction were used to compare differences between the two attachments and among the three models (P < 0.05). The lateral force exerted to the inclined mini-implant was significantly greater than that borne by a vertical mini-implant for both attachment types. The lateral force on the 20° inclined mini-implants with bar attachments was smaller than that on mini-implants with ball attachments. Inclined mini-implants are subjected to greater stresses than vertical ones, and a bar attachment can reduce the lateral forces borne by the mini-implant when one mini-implant inclined at 20°. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The mini-cog: a cognitive 'vital signs' measure for dementia screening in multi-lingual elderly.

PubMed

Borson, S; Scanlan, J; Brush, M; Vitaliano, P; Dokmak, A

2000-11-01

The Mini-Cog, a composite of three-item recall and clock drawing, was developed as a brief test for discriminating demented from non-demented persons in a community sample of culturally, linguistically, and educationally heterogeneous older adults. All 129 who met criteria for probable dementia based on informant interviews and 120 with no history of cognitive decline were included; 124 were non-English speakers. Sensitivity, specificity, and diagnostic value of the Mini-Cog were compared with those of the Mini-Mental State Exam (MMSE) and Cognitive Abilities Screening Instrument (CASI). The Mini-Cog had the highest sensitivity (99%) and correctly classified the greatest percentage (96%) of subjects. Moreover, its diagnostic value was not influenced by education or language, while that of the CASI was adversely influenced by low education, and both education and language compromised the diagnostic value of the MMSE. Administration time for the Mini-Cog was 3 minutes vs 7 minutes for the MMSE. The Mini-Cog required minimal language interpretation and training to administer, and no test forms of scoring modifications were needed to compensate for the extensive linguistic and educational heterogeneity of the sample. Validation in clinical and population-based samples is warranted, as its brevity and ease of administration suggest that the Mini-Cog might be readily incorporated into general practice and senior care settings as a routine 'cognitive vital signs' measure. Copyright 2000 John Wiley & Sons, Ltd.

Corneal oedema in a unilateral corneal graft patient induced by high Dk mini-scleral contact lens.

PubMed

Guillon, Natalie C; Godfrey, Andrew; Hammond, David S

2018-05-24

Scleral contact lenses are increasingly becoming accepted as the method of choice for visual correction of the irregular cornea. As such, cases have surfaced which demonstrate complications arising from mini-scleral lenses. Identification of these issues and adjusting fitting techniques accordingly is necessary for reducing the risks associated with mini-scleral lens wear. A 58 year old Caucasian female was referred for rigid gas permeable contact lens fitting for correction of right irregular astigmatism post penetrating keratoplasty. After four months of successful mini-scleral contact lens wear, the patient experienced a graft rejection episode and treated accordingly, then refit with a new mini-scleral lens. Five months after the lens refit, the patient presented with complaints of hazy vision, and a diagnosis of lens-induced corneal oedema made. Increased awareness of the potential complications of mini-scleral lenses is necessary to encourage and enforce mini-scleral lens fitting techniques that meet the requirements of minimum vault but adequate protection of the compromised cornea. Copyright © 2018 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

Roughness and wettability effect on histological and mechanical response of self-drilling orthodontic mini-implants.

PubMed

Espinar-Escalona, Eduardo; Bravo-Gonzalez, Luis-Alberto; Pegueroles, Marta; Gil, Francisco Javier

2016-06-01

Self-drilling orthodontic mini-implants can be used as temporary devices for orthodontic treatments. Our main goal was to evaluate surface characteristics, roughness and wettability, of surface modified mini-implants to increase their stability during orthodontic treatment without inducing bone fracture and tissue destruction during unscrewing. Modified mini-implants by acid etching, grit-blasting and its combination were implanted in 20 New Zealand rabbits during 10 weeks. After that, the bone-to-implant (BIC) parameter was determined and the torque during unscrewing was measured. The surface characteristics, roughness and wettability, were also measured, onto modified Ti c.p. discs. Acid-etched mini-implants (R a ≈ 1.7 μm, contact angle (CA) ≈ 66°) significantly improved the bone-to-implant parameter, 26 %, compared to as-machined mini-implants (R a ≈ 0.3 μm, CA ≈ 68°, BIC = 19 %) due to its roughness. Moreover, this surface treatment did not modify torque during unscrewing due to their statistically similar wettability (p > 0.05). Surface treatments with higher roughness and hydrophobicity (R a ≈ 4.5 μm, CA ≈ 74°) lead to a greater BIC and to a higher removal torque during unscrewing, causing bone fracture, compared to as-machined mini-implants. Based on these in vivo findings, we conclude that acid-etching surface treatment can support temporary anchoring of titanium mini-implants. This treatment represents a step forward in the direction of reducing the time prior to mini-implant loading by increasing their stability during orthodontic treatment, without inducing bone fracture and tissue destruction during unscrewing.

Curiosity Conducting Mini-Drill Test at Mojave

NASA Image and Video Library

2015-01-14

This view NASA Curiosity Mars Rover shows the rover drill in position for a mini-drill test to assess whether a rock target called Mojave is appropriate for full-depth drilling to collect a sample. It was taken on Jan. 13, 2015.

Effects of monocortical and bicortical mini-implant anchorage on bone-borne palatal expansion using finite element analysis.

PubMed

Lee, Robert J; Moon, Won; Hong, Christine

2017-05-01

Bone-borne palatal expansion relies on mini-implant stability for successful orthopedic expansion. The large magnitude of applied force experienced by mini-implants during bone-borne expansion may lead to high failure rates. Use of bicortical mini-implant anchorage rather than monocortical anchorage may improve mini-implant stability. The aims of this study were to analyze and compare the effects of bicortical and monocortical anchorages on stress distribution and displacement during bone-borne palatal expansion using finite element analysis. Two skull models were constructed to represent expansion before and after midpalatal suture opening. Three clinical situations with varying mini-implant insertion depths were studied in each skull model: monocortical, 1-mm bicortical, and 2.5-mm bicortical. Finite element analysis simulations were performed for each clinical situation in both skull models. Von Mises stress distribution and transverse displacement were evaluated for all models. Peri-implant stress was greater in the monocortical anchorage model compared with both bicortical anchorage models. In addition, transverse displacement was greater and more parallel in the coronal plane for both bicortical models compared with the monocortical model. Minimal differences were observed between the 1-mm and the 2.5-mm bicortical models for both peri-implant stress and transverse displacement. Bicortical mini-implant anchorage results in improved mini-implant stability, decreased mini-implant deformation and fracture, more parallel expansion in the coronal plane, and increased expansion during bone-borne palatal expansion. However, the depth of bicortical mini-implant anchorage was not significant. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

Effects of monocortical and bicortical mini-implant anchorage on bone-borne palatal expansion using finite element analysis

PubMed Central

Lee, Robert J.; Moon, Won; Hong, Christine

2017-01-01

Introduction Bone-borne palatal expansion relies on mini-implant stability for successful orthopedic expansion. The large magnitude of applied force experienced by mini-implants during bone-borne expansion may lead to high failure rates. Use of bicortical mini-implant anchorage rather than monocortical anchorage may improve mini-implant stability. The aim of this study was to analyze and compare the effects of bicortical and monocortical anchorage on stress distribution and displacement during bone-borne palatal expansion using finite element analysis (FEA). Methods Two skull models were constructed to represent expansion prior to and after midpalatal suture opening. Three clinical situations with varying mini-implant insertion depths were studied in each skull model: monocortical, 1mm bicortical, and 2.5mm bicortical. FEA simulations were performed for each clinical situation in both skull models. Von Mises stress distribution and transverse displacement was evaluated for all models. Results Peri-implant stress was greater in the monocortical anchorage model compared to both bicortical anchorage models. In addition, transverse displacement was greater and more parallel in the coronal plane for both bicortical models compared to the monocortical model. Minimal differences were observed between the 1mm bicortical and 2.5mm bicortical models for both peri-implant stress and transverse displacement. Conclusions Bicortical mini-implant anchorage results in improved mini-implant stability, decreased mini-implant deformation and fracture, more parallel expansion in the coronal plane, and increased expansion during bone-borne palatal expansion. However, the depth of bicortical mini-implant anchorage was not significant. PMID:28457266

Rapid assessment of tinnitus-related psychological distress using the Mini-TQ.

PubMed

Hiller, Wolfgang; Goebel, Gerhard

2004-01-01

The aim of this study was to develop an abridged version of the Tinnitus Questionnaire (TQ) to be used as a quick tool for the assessment of tinnitus-related psychological distress. Data from 351 inpatients and 122 outpatients with chronic tinnitus were used to analyse item statistics and psychometric properties. Twelve items with an optimal combination of high item-total correlations, reliability and sensitivity in assessing changes were selected for the Mini-TQ. Correlation with the full TQ was >0.90, and test-retest reliability was 0.89. Validity was confirmed by associations with general psychological symptom patterns. Treatment effects indicated by the Mini-TQ were slightly greater than those indicated by the full TQ. The Mini-TQ is recommended as a psychometrically approved and solid tool for rapid and economical assessment of subjective tinnitus distress.

Effect of gamma irradiation on nutrient digestibility in SPF mini-pig

NASA Astrophysics Data System (ADS)

Lee, Jun-Yeob; Cho, Sung-Back; Kim, Yoo-Yong; Ohh, Sang-Jip

2011-01-01

This study was carried out to evaluate the effect of gamma irradiation on nutrient digestibility of either soy-based or milk-based diet for specific pathogen-free (SPF) mini-pigs. Gamma irradiation of the diets was done at dosage of 10 kGy with 60Co whereas autoclaving was executed at 121 °C for 20 min. Apparent crude protein digestibilities of gamma irradiated diets were higher ( p<0.05) than those of autoclaved diets regardless of diet type. Digestibilities of dry matter, gross energy and total carbohydrate in the irradiated diet were higher than those of the autoclaved diet. From the results of nutrient digestibility of mini-pig diets in this study, 10 kGy gamma radiation was suggested as a convenient diet radicidation method that can minimize the decrease in nutrient digestibility on feeding to SPF mini-pigs.

Incorporating Inquiry into Upper-Level Homework Assignments: The Mini-Journal

NASA Astrophysics Data System (ADS)

Whittington, A. G.; Speck, A. K.; Witzig, S. B.; Abell, S. K.

2009-12-01

The U.S. National Science Education Standards provide guidelines for teaching science through inquiry, where students actively develop their understanding of science by combining scientific knowledge with reasoning and thinking skills. Inquiry activities include reading scientific literature, generating hypotheses, designing and carrying out investigations, interpreting data, and formulating conclusions. Inquiry-based instruction emphasizes questions, evidence, and explanation, the essential features of inquiry. As part of an NSF-funded project, “CUES: Connecting Undergraduates to the Enterprise of Science,” new inquiry-based homework materials were developed for two upper-level classes at the University of Missouri: Geochemistry (required for Geology majors), and Solar System Science (open to seniors and graduate students, co-taught and cross-listed between Geology and Physics & Astronomy). We engage students in inquiry-based learning by presenting homework exercises as “mini-journal” articles that follow the format of a scientific journal article, including a title, authors, abstract, introduction, methods, results, discussion and citations to peer-reviewed literature. The mini-journal provides a scaffold and serves as a springboard for students to develop and carry out their own follow-up investigation. They then present their findings in the form of their own mini-journal. Mini-journals replace traditional homework problem sets with a format that more directly reflects and encourages scientific practice. Students are engaged in inquiry-based homework which encompass doing, thinking, and communicating, while the minijournal allows the instructor to contain lines of inquiry within the limits posed by available resources. In the examples we present, research is conducted via spreadsheet modeling, where the students develop their own spreadsheets. The key differences between the old and new formats include (i) the active participation of the students in

Mini-Uav LIDAR for Power Line Inspection

NASA Astrophysics Data System (ADS)

Teng, G. E.; Zhou, M.; Li, C. R.; Wu, H. H.; Li, W.; Meng, F. R.; Zhou, C. C.; Ma, L.

2017-09-01

Light detection and ranging (LIDAR) system based on unmanned aerial vehicles (UAVs) recently are in rapid advancement, meanwhile portable and flexible mini-UAV-borne laser scanners have been a hot research field, especially for the complex terrain survey in the mountains and other areas. This study proposes a power line inspection system solution based on mini-UAV-borne LIDAR system-AOEagle, developed by Academy of Opto-Electronics, Chinese Academy of Sciences, which mounted on a Multi-rotor unmanned aerial vehicle for complex terrain survey according to real test. Furthermore, the point cloud data was explored to validate its applicability for power line inspection, in terms of corridor and line laser point clouds; deformation detection of power towers, etc. The feasibility and advantages of AOEagle have been demonstrated by the promising results based on the real-measured data in the field of power line inspection.

Evaluation of cytotoxicity and corrosion resistance of orthodontic mini-implants

PubMed Central

Alves, Celha Borges Costa; Segurado, Márcio Nunes; Dorta, Miriam Cristina Leandro; Dias, Fátima Ribeiro; Lenza, Maurício Guilherme; Lenza, Marcos Augusto

2016-01-01

ABSTRACT Objective: To evaluate and compare in vitro cytotoxicity and corrosion resistance of mini-implants from three different commercial brands used for orthodontic anchorage. Methods: Six mini-implants (Conexão(tm), Neodent(tm) and SIN(tm)) were separately immersed in artificial saliva (pH 6.76) for 30 and 60 days. The cytotoxicity of the corrosion extracts was assessed in L929 cell cultures using the violet crystal and MTT assays, as well as cell morphology under light microscopy. Metal surface characteristics before and after immersion in artificial saliva were assessed by means of scanning electron microscopy (SEM). The samples underwent atomic absorption spectrophotometry to determine the concentrations of aluminum and vanadium ions, constituent elements of the alloy that present potential toxicity. For statistical analysis, one-way ANOVA/Bonferroni tests were used for comparisons among groups with p < 0.05 considered significant. Statistical analysis was carried out with Graph Pad PRISM software Version 4.0. Results: No changes in cell viability or morphology were observed. Mini-implants SEM images revealed smooth surfaces with no obvious traces of corrosion. The extracts assessed by means of atomic absorption spectrophotometry presented concentrations of aluminum and vanadium ions below 1.0 µg/mL and 0.5 µg/mL, respectively. Conclusion: Orthodontic mini-implants manufactured by Conexão(tm), Neodent(tm) and SIN(tm) present high corrosion resistance and are not cytotoxic. PMID:27901227

αA-Crystallin–Derived Mini-Chaperone Modulates Stability and Function of Cataract Causing αAG98R-Crystallin

PubMed Central

Raju, Murugesan; Santhoshkumar, Puttur; Sharma, K. Krishna

2012-01-01

Background A substitution mutation in human αA-crystallin (αAG98R) is associated with autosomal dominant cataract. The recombinant mutant αAG98R protein exhibits altered structure, substrate-dependent chaperone activity, impaired oligomer stability and aggregation on prolonged incubation at 37°C. Our previous studies have shown that αA-crystallin–derived mini-chaperone (DFVIFLDVKHFSPEDLTVK) functions like a molecular chaperone by suppressing the aggregation of denaturing proteins. The present study was undertaken to determine the effect of αA-crystallin–derived mini-chaperone on the stability and chaperone activity of αAG98R-crystallin. Methodology/Principal Findings Recombinant αAG98R was incubated in presence and absence of mini-chaperone and analyzed by chromatographic and spectrometric methods. Transmission electron microscope was used to examine the effect of mini-chaperone on the aggregation propensity of mutant protein. Mini-chaperone containing photoactive benzoylphenylalanine was used to confirm the interaction of mini-chaperone with αAG98R. The rescuing of chaperone activity in mutantα-crystallin (αAG98R) by mini-chaperone was confirmed by chaperone assays. We found that the addition of the mini-chaperone during incubation of αAG98R protected the mutant crystallin from forming larger aggregates that precipitate with time. The mini-chaperone-stabilized αAG98R displayed chaperone activity comparable to that of wild-type αA-crystallin. The complexes formed between mini-αA–αAG98R complex and ADH were more stable than the complexes formed between αAG98R and ADH. Western-blotting and mass spectrometry confirmed the binding of mini-chaperone to mutant crystallin. Conclusion/Significance These results demonstrate that mini-chaperone stabilizes the mutant αA-crystallin and modulates the chaperone activity of αAG98R. These findings aid in our understanding of how to design peptide chaperones that can be used to stabilize mutant �

Replacing the AMOR with the miniDOAS in the ammonia monitoring network in the Netherlands

NASA Astrophysics Data System (ADS)

Berkhout, Augustinus J. C.; Swart, Daan P. J.; Volten, Hester; Gast, Lou F. L.; Haaima, Marty; Verboom, Hans; Stefess, Guus; Hafkenscheid, Theo; Hoogerbrugge, Ronald

2017-11-01

In this paper we present the continued development of the miniDOAS, an active differential optical absorption spectroscopy (DOAS) instrument used to measure ammonia concentrations in ambient air. The miniDOAS has been adapted for use in the Dutch National Air Quality Monitoring Network. The miniDOAS replaces the life-expired continuous-flow denuder ammonia monitor (AMOR). From September 2014 to December 2015, both instruments measured in parallel before the change from AMOR to miniDOAS was made. The instruments were deployed at six monitoring stations throughout the Netherlands. We report on the results of this intercomparison. Both instruments show a good uptime of ca. 90 %, adequate for an automatic monitoring network. Although both instruments produce 1 min values of ammonia concentrations, a direct comparison on short timescales such as minutes or hours does not give meaningful results because the AMOR response to changing ammonia concentrations is slow. Comparisons between daily and monthly values show good agreement. For monthly averages, we find a small average offset of 0.65 ± 0.28 µg m-3 and a slope of 1.034 ± 0.028, with the miniDOAS measuring slightly higher than the AMOR. The fast time resolution of the miniDOAS makes the instrument suitable not only for monitoring but also for process studies.

Direct typing of Canine parvovirus (CPV) from infected dog faeces by rapid mini sequencing technique.

PubMed

V, Pavana Jyothi; S, Akila; Selvan, Malini K; Naidu, Hariprasad; Raghunathan, Shwethaa; Kota, Sathish; Sundaram, R C Raja; Rana, Samir Kumar; Raj, G Dhinakar; Srinivasan, V A; Mohana Subramanian, B

2016-12-01

Canine parvovirus (CPV) is a non-enveloped single stranded DNA virus with an icosahedral capsid. Mini-sequencing based CPV typing was developed earlier to detect and differentiate all the CPV types and FPV in a single reaction. This technique was further evaluated in the present study by performing the mini-sequencing directly from fecal samples which avoided tedious virus isolation steps by cell culture system. Fecal swab samples were collected from 84 dogs with enteritis symptoms, suggestive of parvoviral infection from different locations across India. Seventy six of these samples were positive by PCR; the subsequent mini-sequencing reaction typed 74 of them as type 2a virus, and 2 samples as type 2b. Additionally, 25 of the positive samples were typed by cycle sequencing of PCR products. Direct CPV typing from fecal samples using mini-sequencing showed 100% correlation with CPV typing by cycle sequencing. Moreover, CPV typing was achieved by mini-sequencing even with faintly positive PCR amplicons which was not possible by cycle sequencing. Therefore, the mini-sequencing technique is recommended for regular epidemiological follow up of CPV types, since the technique is rapid, highly sensitive and high capacity method for CPV typing. Copyright © 2016. Published by Elsevier B.V.

Protective Factor Screening for Prevention Practice: Sensitivity and Specificity of the Dessa-Mini

ERIC Educational Resources Information Center

Shapiro, Valerie B.; Kim, B. K. Elizabeth; Robitaille, Jennifer L.; LeBuffe, Paul A.

2017-01-01

The Devereux Student Strengths Assessment Mini (DESSA-Mini; Naglieri, LeBuffe, & Shapiro, 2011/2014) was designed to overcome practical obstacles to universal prevention screening. This article seeks to determine whether an entirely strength-based, 8-item screening instrument achieves technical accuracy in routine practice. Data come from a…

Agreement between clinical and MINI diagnoses in outpatients with mood and anxiety disorders.

PubMed

Verhoeven, F E A; Swaab, L S M A; Carlier, I V E; van Hemert, A M; Zitman, F G; Ruhé, H G; Schoevers, R A; Giltay, E J

2017-10-15

Standardized Diagnostic Interviews (SDIs) such as the Mini International Neuropsychiatric Interview (MINI) are widely used to systematically screen for psychiatric disorders in research. To support generalizability of results to clinical practice, we assessed agreement between the MINI and clinical diagnoses. Agreement was assessed in a large, real life dataset (n = 7016) using concordance statistics such as sensitivity, specificity, efficiency and area under the curve (AUC). 41.5% of clinical diagnoses were mood disorders, 26.5% were anxiety disorders. Overall, we found moderate agreement between MINI and clinical diagnoses (median efficiency: 0.92, median AUC: 0.79). For mood disorders, the AUC for all participants showed a range between 0.55 and 0.81 (median: 0.73), and for anxiety disorders the AUC ranged from 0.78 to 0.88 (median: 0.83). The AUC showed better agreement for mood disorders in the single diagnosis group than in the total group (median 0.77 vs. 0.71). For anxiety disorders, the AUC for the single diagnosis group was comparable to the AUC of the total group (median: 0.81 vs. 0.83 respectively). Numbers of false positives were high for both mood and anxiety diagnoses, but less so in the single diagnosis group. Time lag between MINI and clinical diagnosis, the availability of only the primary clinical diagnosis, and relatively high severity of the current sample are limitations of the current study. Agreement between MINI and clinical diagnoses was moderate at best, which partly reflects the difference between the different measures used in the current study. Copyright © 2017 Elsevier B.V. All rights reserved.

Mu-driven transposition of recombinant mini-Mu unit DNA in the Corynebacterium glutamicum chromosome.

PubMed

Gorshkova, Natalya V; Lobanova, Juliya S; Tokmakova, Irina L; Smirnov, Sergey V; Akhverdyan, Valerii Z; Krylov, Alexander A; Mashko, Sergey V

2018-03-01

A dual-component Mu-transposition system was modified for the integration/amplification of genes in Corynebacterium. The system consists of two types of plasmids: (i) a non-replicative integrative plasmid that contains the transposing mini-Mu(LR) unit bracketed by the L/R Mu ends or the mini-Mu(LER) unit, which additionally contains the enhancer element, E, and (ii) an integration helper plasmid that expresses the transposition factor genes for MuA and MuB. Efficient transposition in the C. glutamicum chromosome (≈ 2 × 10 -4 per cell) occurred mainly through the replicative pathway via cointegrate formation followed by possible resolution. Optimizing the E location in the mini-Mu unit significantly increased the efficiency of Mu-driven intramolecular transposition-amplification in C. glutamicum as well as in gram-negative bacteria. The new C. glutamicum genome modification strategy that was developed allows the consequent independent integration/amplification/fixation of target genes at high copy numbers. After integration/amplification of the first mini-Mu(LER) unit in the C. glutamicum chromosome, the E-element, which is bracketed by lox-like sites, is excised by Cre-mediated fashion, thereby fixing the truncated mini-Mu(LR) unit in its position for the subsequent integration/amplification of new mini-Mu(LER) units. This strategy was demonstrated using the genes for the citrine and green fluorescent proteins, yECitrine and yEGFP, respectively.

Ductless Mini-Split Heat Pump Comfort Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roth, K.; Sehgal, N.; Akers, C.

2013-03-01

Field tests were conducted in two homes in Austin, TX to evaluate the comfort performance of ductless mini-split heat pumps (DMSHPs), measuring temperature and relative humidity measurements in four rooms in each home before and after retrofitting a central HVAC system with DMSHPs.

Teacher Supervision and Evaluation: A Case Study of Administrators' and Teachers' Perceptions of Mini Observations

ERIC Educational Resources Information Center

Campbell, Thomas F.

2013-01-01

This case study will investigate teachers' and administrators' perceptions of the relationship between mini observations and teacher performance to understand what effect, if any, a system of mini observations has on teacher performance, and if mini observations influences a teacher's pedagogical practice differently than a…

Miniature Optical Wide-Angle-Lens Startracker (Mini-OWLS)

NASA Astrophysics Data System (ADS)

Miller, Rick; Coulter, Joe E.; Levine, Seymour

1993-02-01

This paper provides a brief overview of the design considerations and the current status of the Miniature Optical Wide-Angle Lens Startracker Program. Mini-OWLS offers a revolutionary alternative to the conventional startracker. It is a small, lightweight, low cost, high performance startracker that can be used in a variety of applications including calibration and alignment of Inertial Measurement Units (IMU's) Mini-OWLS makes use of a strap down design incorporating Holographic Optical Elements (HOES) in place of conventional optics. HOES can be multiplexed so that the same aperture can be used for multiple separate optical paths looking in several directions simultaneously without startracker rotation. Additionally, separate Schmidt corrector plates are not required to compensate for spherical aberration. The optical assembly, or what would normally be considered as the telescope, is less than 20 cc in volume, weighs less than 55 grams, and contains the equivalent of three individual telescopes. Each one has a 4 deg Field of View (FOV) with a field of regard of 48 square degrees. Mini-OWLS has a bandwidth of approximately 300 nm in or near the visible wavelength. The projected resolution of the startracker is 5 to 10 arcseconds, depending on the centroiding algorithm used. The Mini-OWLS program was initiated last year and represents a miniaturized version of a similar design for aeronautical applications. The contract is managed by Wright Laboratory, Air Force Systems Command, Wright-Patterson AFB, Ohio, with funding from the Strategic Defense Initiative Organization through Eglin AFB. The initial phase of the program is to build and test a development unit. The second phase is to integrate the startracker with the Charles Stark Draper Laboratory Micromechanical Inertial Guidance System (MIGS) and the Signal Processing Packaging Design (SPPD) being developed by Texas Instruments. The preliminary design review was conducted in November 1991. Three-axes prototype

Miniature Optical Wide-Angle-Lens Startracker (Mini-OWLS)

NASA Technical Reports Server (NTRS)

Miller, Rick; Coulter, Joe E.; Levine, Seymour

1993-01-01

This paper provides a brief overview of the design considerations and the current status of the Miniature Optical Wide-Angle Lens Startracker Program. Mini-OWLS offers a revolutionary alternative to the conventional startracker. It is a small, lightweight, low cost, high performance startracker that can be used in a variety of applications including calibration and alignment of Inertial Measurement Units (IMU's) Mini-OWLS makes use of a strap down design incorporating Holographic Optical Elements (HOES) in place of conventional optics. HOES can be multiplexed so that the same aperture can be used for multiple separate optical paths looking in several directions simultaneously without startracker rotation. Additionally, separate Schmidt corrector plates are not required to compensate for spherical aberration. The optical assembly, or what would normally be considered as the telescope, is less than 20 cc in volume, weighs less than 55 grams, and contains the equivalent of three individual telescopes. Each one has a 4 deg Field of View (FOV) with a field of regard of 48 square degrees. Mini-OWLS has a bandwidth of approximately 300 nm in or near the visible wavelength. The projected resolution of the startracker is 5 to 10 arcseconds, depending on the centroiding algorithm used. The Mini-OWLS program was initiated last year and represents a miniaturized version of a similar design for aeronautical applications. The contract is managed by Wright Laboratory, Air Force Systems Command, Wright-Patterson AFB, Ohio, with funding from the Strategic Defense Initiative Organization through Eglin AFB. The initial phase of the program is to build and test a development unit. The second phase is to integrate the startracker with the Charles Stark Draper Laboratory Micromechanical Inertial Guidance System (MIGS) and the Signal Processing Packaging Design (SPPD) being developed by Texas Instruments. The preliminary design review was conducted in November 1991. Three-axes prototype

Playing Around in the Solar System: Mini-games for Many Missions

NASA Astrophysics Data System (ADS)

Fisher, D. K.; Leon, N.; Fitzpatrick, A. J.; Wessen, A.

2010-12-01

Several NASA solar system missions will have major milestones during 2011, the Year of the Solar System. These events include launches, encounters, and orbit insertions. Other missions will continue the explorations already underway. The “Year of the Solar System Game” on The Space Place website (http://spaceplace.nasa.gov/en/kids/solar-system) brings all these efforts together in the context of the whole solar system. The game helps to build awareness of the characteristics of our solar system and some of the missions that are continuing to advance our knowledge and understanding. It is one of many educational tools being developed and deployed for the Year of the Solar System. The game is a “super-game” that encompasses a number of mission-related “mini-games.” The mini-games can be played individually, and they all contribute toward achievements in the super-game. The enveloping interface for all the games is an animated solar system. The player clicks on a planet or a moon, sees a close-up image, and reads a short paragraph about the object. If the object has been endowed with a mission mini-game, player can click on the tiny spacecraft, read about the mission, then play the game—or, if impatient, just immediately play the game (and read about the mission later, we hope). A score “page” keeps track of the player’s achievements and scores. Players earn achievements by reading about the planets, moons, asteroids, comets, and missions and by playing the mission mini-games. The game targets upper elementary age children, as does the entire Space Place website. Each mini-game, although simple, incorporates elements of the spacecrafts’ missions and their target objects. For example, in Cassini Commander, the player must navigate the Cassini spacecraft through gaps in Saturn’s rings and around Saturn’s moons. The super-game is designed to accommodate any number of mission mini-games, so we are hoping to continue to add missions and increase

Hematite spherules at Meridiani: Results from MI, Mini-TES, and Pancam

NASA Astrophysics Data System (ADS)

Calvin, W. M.; Shoffner, J. D.; Johnson, J. R.; Knoll, A. H.; Pocock, J. M.; Squyres, S. W.; Weitz, C. M.; Arvidson, R. E.; Bell, J. F.; Christensen, P. R.; de Souza, P. A.; Farrand, W. H.; Glotch, T. D.; Herkenhoff, K. E.; Jolliff, B. L.; Knudson, A. T.; McLennan, S. M.; Rogers, A. D.; Thompson, S. D.

2008-12-01

We report on observations of hematite-bearing spherules at Meridiani Planum made using the Microscopic Imager (MI), Mini-Thermal Emission Spectrometer (Mini-TES), and Panoramic Camera (Pancam) instruments on the Mars Exploration Rover Opportunity. Spherules were observed on soil surfaces and in outcrop rocks, both on undisturbed surfaces and in abraded surfaces ground using the Rock Abrasion Tool (RAT). Spherule size and shape change little along the 850 m eastward traverse from Eagle Crater to Endurance Crater, but spherules decrease and then slightly increase in size along the 6 km traverse from Endurance south to Victoria Crater. Local populations range from submillimeters to several millimeters in diameter. An additional small diameter (100 μm) size population is possible. An increase in irregular shapes is found near Victoria Crater. This, combined with the size decrease south of Endurance, suggests either a changing depositional environment, or variation in the duration and timing of diagenetic events. The dominant smaller size population observed early in the mission in aeolian areas and ripple crests is observed as the primary size population in abraded outcrop farther south. This suggests that successively younger beds are exposed at the surface along the southward traverse. Stratigraphically higher units removed by erosion could be recorded by the present surface lag deposit. Coordinated systematic observations are used to determine optical and infrared hematite indices of the surface soils in Pancam and Mini-TES. In spite of the systematic variation seen in MI, both Pancam and Mini-TES indices are highly variable based on the local surface, and neither show systematic trends south of Endurance. The lack of a 390 cm-1 feature in Mini-TES spectra suggests concentric or radial interior structure within the spherules at scales too fine for MI to observe. Mini-TES does not detect any silicate component in the spherules. A bound water component in soils or in

Mini-percutaneous nephrolithotomy for stones in anomalous-kidneys: a prospective study.

PubMed

Khadgi, Sanjay; Shrestha, Babu; Ibrahim, Hamdy; Shrestha, Sunil; ElSheemy, Mohammed S; Al-Kandari, Ahmed M

2017-08-01

To evaluate safety and efficacy of minipercutaneous nephrolithotomy (Mini-PNL) in management of stones in different types of renal anomalies. Patients with stones ≥2 cm or SWL-resistant stones in anomalous-kidneys treated by Mini-PNL between March 2010 and September 2012 were included prospectively. Mini-PNL was done under regional anesthesia in prone position with fluoroscopic guidance through 18 Fr sheath using semirigid ureteroscope (8.5/11.5 Fr) and pneumatic lithotripter. All patients were followed-up for 2-3 years. Stone-free rate was defined as absence of residual fragments ≥2 mm. Student-T, Mann-Whitney, Chi square (χ 2 ), Fisher-exact, one way ANOVA or Kruskal-Wallis test were used for analysis. Mini-PNL was performed for 59 patients (20 horseshoe, 15 malrotated, 7 polycystic, 13 duplex and 4 ectopic pelvic-kidneys). Mean age was 40.18 ± 12.75 (14-78) years. Mean stone burden was 31.72 ± 21.43 (7.85-141.3) mm 2 . Two tracts were required in 7 (11.9 %) patients. Tubeless Mini-PNL with double-J insertion was performed in all patients except two. Operative time was 50.17 ± 18.73 (15-105) min. Hemoglobin loss was 0.44 ± 0.30 (0-1.4) g/dL. Complications were reported in 15 (25.4 %) patients. No pleural injury, sepsis, perinephric-collection or renal-pelvis perforation were reported. Stone-free rate was 89.8 % (converted to open-surgery in one patient, second-look PNL in two patients, auxiliary SWL in three patients). Stone-free rate improved to 98.3 % after retreatment and auxiliary SWL. Site of puncture was mostly upper calyceal in horseshoe-kidney (80 %), mid calyceal in polycystic-kidney (85.7 %) and lower calyceal in duplex-kidney (46.2 %). Punctures were also significantly infracostal in horseshoe-kidney (100 %) and supracostal in both duplex (53.8 %) and malrotated-kidneys (66.7 %). Mini-PNL is safe for management of stones in anomalous-kidney with SFR comparable to standard-PNL but with less complications.

Hematite spherules at Meridiani: results from MI, Mini-TES, and Pancam

USGS Publications Warehouse

Calvin, W.M.; Shoffner, J.D.; Johnson, J. R.; Knoll, A.H.; Pocock, J.M.; Squyres, S. W.; Weitz, C.M.; Arvidson, R. E.; Bell, J.F.; Christensen, P.R.; de Souza, P. A.; Farrand, W. H.; Glotch, T.D.; Herkenhoff, K. E.; Jolliff, B.L.; Knudson, A.T.; McLennan, S.M.; Rogers, A.D.; Thompson, S.D.

2008-01-01

We report on observations of hematite-bearing spherules at Meridiani Planum made using the Microscopic Imager (MI), Mini-Thermal Emission Spectrometer (Mini-TES), and Panoramic Camera (Pancam) instruments on the Mars Exploration Rover Opportunity. Spherules were observed on soil surfaces and in outcrop rocks, both on undisturbed surfaces and in abraded surfaces ground using the Rock Abrasion Tool (RAT). Spherule size and shape change little along the 850 m eastward traverse from Eagle Crater to Endurance Crater, but spherules decrease and then slightly increase in size along the 6 km traverse from Endurance south to Victoria Crater. Local populations range from submillimeters to several millimeters in diameter. An additional small diameter (100 μm) size population is possible. An increase in irregular shapes is found near Victoria Crater. This, combined with the size decrease south of Endurance, suggests either a changing depositional environment, or variation in the duration and timing of diagenetic events. The dominant smaller size population observed early in the mission in aeolian areas and ripple crests is observed as the primary size population in abraded outcrop farther south. This suggests that successively younger beds are exposed at the surface along the southward traverse. Stratigraphically higher units removed by erosion could be recorded by the present surface lag deposit. Coordinated systematic observations are used to determine optical and infrared hematite indices of the surface soils in Pancam and Mini-TES. In spite of the systematic variation seen in MI, both Pancam and Mini-TES indices are highly variable based on the local surface, and neither show systematic trends south of Endurance. The lack of a 390 cm?1 feature in Mini-TES spectra suggests concentric or radial interior structure within the spherules at scales too fine for MI to observe. Mini-TES does not detect any silicate component in the spherules. A bound water component in soils or in

Case studies on local orthodontic traction by minis-implants before implant rehabilitation

PubMed Central

Shen, Pei; Xu, Wei-Feng; Ma, Zhi-Gui; Zhang, Shan-Yong; Zhang, Ying

2015-01-01

Objective: Dentition defect with malocclusion is a common occurrence in the clinical work. To restore proper occlusion, preprosthetic corrections of these malposed teeth are often indispensible. The use of orthodontic mini-implants as temporary anchorage devices provides a plausible treatment for those patients with local problems. The aim of this study was to present two cases using local orthodontic traction in conjunction with mini-implants to provide necessary conditions for implant rehabilitation in three dimensional space. Clinical consideration: Two cases who had dentition defect with malocclusion were included in the present study. As both of them rejected crown reduction or orthodontics treatment, local orthodontic traction by mini-implants was used to restore normal space for implant rehabilitation in three dimensions. Careful mechanics analysis and personalized mechanical device were under consideration. The results showed that the biological responses of the corrected teeth and the surrounding bony structures appeared normal and acceptable. Moreover the patients achieved an ideal local occlusion with a short treatment time. Conclusion: In conclusion local orthodontic traction by mini-implants was a less-invasive and short-term method with favorable effects and less necessary occlusal adjustments. PMID:26221389

Typing of canine parvovirus isolates using mini-sequencing based single nucleotide polymorphism analysis.

PubMed

Naidu, Hariprasad; Subramanian, B Mohana; Chinchkar, Shankar Ramchandra; Sriraman, Rajan; Rana, Samir Kumar; Srinivasan, V A

2012-05-01

The antigenic types of canine parvovirus (CPV) are defined based on differences in the amino acids of the major capsid protein VP2. Type specificity is conferred by a limited number of amino acid changes and in particular by few nucleotide substitutions. PCR based methods are not particularly suitable for typing circulating variants which differ in a few specific nucleotide substitutions. Assays for determining SNPs can detect efficiently nucleotide substitutions and can thus be adapted to identify CPV types. In the present study, CPV typing was performed by single nucleotide extension using the mini-sequencing technique. A mini-sequencing signature was established for all the four CPV types (CPV2, 2a, 2b and 2c) and feline panleukopenia virus. The CPV typing using the mini-sequencing reaction was performed for 13 CPV field isolates and the two vaccine strains available in our repository. All the isolates had been typed earlier by full-length sequencing of the VP2 gene. The typing results obtained from mini-sequencing matched completely with that of sequencing. Typing could be achieved with less than 100 copies of standard plasmid DNA constructs or ≤10¹ FAID₅₀ of virus by mini-sequencing technique. The technique was also efficient for detecting multiple types in mixed infections. Copyright © 2012 Elsevier B.V. All rights reserved.

Development of a Mini-Freeze Dryer for Material-Sparing Laboratory Processing with Representative Product Temperature History.

PubMed

Obeidat, Wasfy M; Sahni, Ekneet; Kessler, William; Pikal, Michael

2018-02-01

The goal of the work described in this publication was to evaluate a new, small, material-sparing freeze dryer, denoted as the "mini-freeze dryer or mini-FD", capable of reproducing the product temperature history of larger freeze dryers, thereby facilitating scale-up. The mini-FD wall temperatures can be controlled to mimic loading procedures and dryer process characteristics of larger dryers. The mini-FD is equipped with a tunable diode laser absorption spectroscopy (TDLAS) water vapor mass flow monitor and with other advanced process analytical technology (PAT) sensors. Drying experiments were performed to demonstrate scalability to larger freeze dryers, including the determination of vial heat transfer coefficients, K v . Product temperature histories during K v runs were evaluated and compared with those obtained with a commercial laboratory-scale freeze dryer (LyoStar II) for sucrose and mannitol product formulations. When the mini-FD wall temperature was set at the LyoStar II band temperature (- 20°C) to mimic lab dryer edge vials, edge vial drying in the mini-FD possessed an average K v within 5% of those obtained during drying in the LyoStar II. When the wall temperature of the mini-FD was set equal to the central vial product temperature, edge vials behaved as center vials, possessing a K v value within 5% of those measured in the LyoStar II. During both K v runs and complete product freeze drying runs, the temperature-time profiles for the average edge vials and central vial in the mini-FD agreed well with the average edge and average central vials of the LyoStar II.

Mini 3D for shallow gas reconnaissance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vallieres, T. des; Enns, D.; Kuehn, H.

1996-12-31

The Mini 3D project was undertaken by TOTAL and ELF with the support of CEPM (Comite d`Etudes Petrolieres et Marines) to define an economical method of obtaining 3D seismic HR data for shallow gas assessment. An experimental 3D survey was carried out with classical site survey techniques in the North Sea. From these data 19 simulations, were produced to compare different acquisition geometries ranging from dual, 600 m long cables to a single receiver. Results show that short offset, low fold and very simple streamer positioning are sufficient to give a reliable 3D image of gas charged bodies. The 3Dmore » data allow a much more accurate risk delineation than 2D HR data. Moreover on financial grounds Mini-3D is comparable in cost to a classical HR 2D survey. In view of these results, such HR 3D should now be the standard for shallow gas surveying.« less

Comparison between McMaster and Mini-FLOTAC methods for the enumeration of Eimeria maxima oocysts in poultry excreta.

PubMed

Bortoluzzi, C; Paras, K L; Applegate, T J; Verocai, G G

2018-04-30

Monitoring Eimeria shedding has become more important due to the recent restrictions to the use of antibiotics within the poultry industry. Therefore, there is a need for the implementation of more precise and accurate quantitative diagnostic techniques. The objective of this study was to compare the precision and accuracy between the Mini-FLOTAC and the McMaster techniques for quantitative diagnosis of Eimeria maxima oocyst in poultry. Twelve pools of excreta samples of broiler chickens experimentally infected with E. maxima were analyzed for the comparison between Mini-FLOTAC and McMaster technique using, the detection limits (dl) of 23 and 25, respectively. Additionally, six excreta samples were used to compare the precision of different dl (5, 10, 23, and 46) using the Mini-FLOTAC technique. For precision comparisons, five technical replicates of each sample (five replicate slides on one excreta slurry) were read for calculating the mean oocyst per gram of excreta (OPG) count, standard deviation (SD), coefficient of variation (CV), and precision of both aforementioned comparisons. To compare accuracy between the methods (McMaster, and Mini-FLOTAC dl 5 and 23), excreta from uninfected chickens was spiked with 100, 500, 1,000, 5,000, or 10,000 OPG; additional samples remained unspiked (negative control). For each spiking level, three samples were read in triplicate, totaling nine reads per spiking level per technique. Data were transformed using log10 to obtain normality and homogeneity of variances. A significant correlation (R = 0.74; p = 0.006) was observed between the mean OPG of the McMaster dl 25 and the Mini-FLOTAC dl 23. Mean OPG, CV, SD, and precision were not statistically different between the McMaster dl 25 and Mini-FLOTAC dl 23. Despite the absence of statistical difference (p > 0.05), Mini-FLOTAC dl 5 showed a numerically lower SD and CV than Mini-FLOTAC dl 23. The Pearson correlation coefficient revealed significant and positive

Mini-implants for Orthodontic Anchorage: Surface Analysis after Redrilling and Sterilization - An in vitro Study.

PubMed

Gross, J M; Nascimento, G G; Araújo, V C; Bönecker, Mjs; Furuse, C

2016-04-01

This study aimed to investigate, in vitro, possible alterations on mini-implants surface after retrieval and if the cleaning process and sterilization can predispose damages. Two commercial mini-implants were tested for deformations after drilling and removing in artificial bone four times. Samples were analyzed by scanning electron microscopy, and surface alterations verified through thread and pitches deformation. To alterations caused by insertion/removal and the cleaning process and sterilization were verified in different procedures: Insertions and sterilization, only insertions, and only sterilization. Photomicrographs were analyzed in order to compare the surface characteristics. Head deformation was verified qualitatively. For a quantitative analysis, distances between threads were measured across the active part of the mini-implants. No deformation was observed in both groups. The cleaning and sterilization processes did not provoke alteration in both groups. Nevertheless, the presence of synthetic bone was noted in some samples. The mean distances between implant threads were similar after all steps in all regions in both groups. The results suggest that the tested mini-implants can be retrieved without damage of its surface after four cycles of insertion, removal, and sterilization. Orthodontic mini-implant, Redrilling, Sterilization. Mini-implants can be retrieved without damage to its surface after four cycles of insertion, removal, and sterilization in the same patient without representing a biological concern.

Evaluating depressive symptoms in hypomanic and manic episodes using a structured diagnostic tool: validation of a new Mini International Neuropsychiatric Interview (M.I.N.I.) module for the DSM-5 'With Mixed Features' specifier.

PubMed

Hergueta, Thierry; Weiller, Emmanuelle

2013-01-01

The Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), includes a new 'With Mixed Features' specifier for mood episodes. In (hypo-)manic episodes, the specifier is given if three or more depressive symptoms are present nearly every day during the episode. A new module of the Mini International Neuropsychiatric Interview (M.I.N.I.) has been developed as a patient-completed questionnaire to evaluate the DSM-5 specifier for (hypo-)manic episodes. The objective of this study was to validate this new module. In Phase I, patients with a manic episode in the past 6 months completed the module and were asked whether the wording was clear, understandable, relevant and specific. Based on their feedback, the module was refined and finalised. In Phase II, psychiatrists each invited five patients to complete the module. The psychiatrists completed record forms for these five patients, which included their diagnoses, made according to DSM-5 criteria during clinical interviewing. The module was validated by comparing depressive symptoms reported by the patients themselves using the M.I.N.I. module with those evaluated by their psychiatrist using DSM-5 criteria during clinical interviewing. In Phase I, a few changes were made to the M.I.N.I. module based on feedback from 20 patients (60% of whom had mixed features). In Phase II, 23 psychiatrists completed record forms for 115 patients, 99 (86.1%) of whom completed the M.I.N.I. module. Agreement between psychiatrists' DSM-5 diagnoses and patients' M.I.N.I. responses was substantial (Cohen's kappa coefficient, 0.60). The overall sensitivity of the M.I.N.I. was 0.91 and its specificity was 0.70. Sensitivity ranged from 0.63 for psychomotor retardation to 0.90 for suicidal thoughts. Specificity ranged from 0.63 for diminished interest/pleasure to 0.90 for suicidal thoughts. The module's positive and negative predictive values were 0.72 and 0.90, respectively. In summary, the M.I.N.I. module demonstrated good

The Rocks of Gusev Crater as Viewed by Mini-TES

NASA Technical Reports Server (NTRS)

Ruff, S. W.; Christensen, P. R.; Blaney, D. L.

2005-01-01

We are developing the means to separate atmospheric spectral features from rock spectra. Measurements made in the late afternoon when the temperature difference between the rocks and sky is the greatest provide spectra that are least impacted by downwelling radiance. Additionally, the long wavelength range of Mini-TES spectra contain spectral features that are least effected by contributions from the atmosphere due to its relative transparency in this range. Mini-TES spectra have thus been used to reveal the geological diversity in Gusev crater and will continue to be a rich source of mineralogical information as Spirit continues its traverse.

A simple eccentric stirred tank mini-bioreactor: mixing characterization and mammalian cell culture experiments.

PubMed

Bulnes-Abundis, David; Carrillo-Cocom, Leydi M; Aráiz-Hernández, Diana; García-Ulloa, Alfonso; Granados-Pastor, Marisa; Sánchez-Arreola, Pamela B; Murugappan, Gayathree; Alvarez, Mario M

2013-04-01

In industrial practice, stirred tank bioreactors are the most common mammalian cell culture platform. However, research and screening protocols at the laboratory scale (i.e., 5-100 mL) rely primarily on Petri dishes, culture bottles, or Erlenmeyer flasks. There is a clear need for simple-easy to assemble, easy to use, easy to clean-cell culture mini-bioreactors for lab-scale and/or screening applications. Here, we study the mixing performance and culture adequacy of a 30 mL eccentric stirred tank mini-bioreactor. A detailed mixing characterization of the proposed bioreactor is presented. Laser induced fluorescence (LIF) experiments and computational fluid dynamics (CFD) computations are used to identify the operational conditions required for adequate mixing. Mammalian cell culture experiments were conducted with two different cell models. The specific growth rate and the maximum cell density of Chinese hamster ovary (CHO) cell cultures grown in the mini-bioreactor were comparable to those observed for 6-well culture plates, Erlenmeyer flasks, and 1 L fully instrumented bioreactors. Human hematopoietic stem cells were successfully expanded tenfold in suspension conditions using the eccentric mini-bioreactor system. Our results demonstrate good mixing performance and suggest the practicality and adequacy of the proposed mini-bioreactor. Copyright © 2012 Wiley Periodicals, Inc.

Use of mini dental implants in ectodermal dysplasia children: follow-up of three cases.

PubMed

Sfeir, E; Nassif, N; Moukarzel, C

2014-07-01

Ectodermal dysplasia is a hereditary genodermatosis characterised by a congenital defect of ectodermal structures, causing tooth malformations and anomalies. Implantology has become accepted in these subjects. However cases are often complicated by a reduction in the size of the alveolar process, making the insertion of conventional implants difficult without bone grafting. The reduced diameter of mini-implants and their ease of insertion provide an interesting solution in supporting removable or fixed prosthesis. The purpose of this paper is to report the follow-up of three cases of children (11-12 year- old) with ectodermal dysplasia in which mini-implants were used to support the prostheses. In the first case, two mini-implants were inserted into the anterior part of the mandible for stabilising a removable denture (2 years follow-up). In the other two cases, mini- implants were inserted in the maxilla and mandible to replace missing front teeth with fixed prostheses. Patients were called for follow- up every 6 months: in the sencod case follow-up lasted 4 years in the mandible and 2 years in the maxilla; in the third case, 2 years in the maxilla and 1 year in the mandible. The use of mini-implants in children with ectodermal dysplasia can enhance aesthetics, and functional and psychosocial development.

Mini-column assay for rapid detection of malachite green in fish.

PubMed

Shalaby, Ali R; Emam, Wafaa H; Anwar, Mervat M

2017-07-01

A simple, rapid and economical mini-column method for detecting malachite green (MG) residue in fish was developed. The method used a column with 2mm ID that was tightly packed with silica gel followed by alumina. Detection of MG was performed by viewing the developed mini-column at visible light by naked eye; where MG was seen as compact green band at the confluence of the silica gel layer with alumina layer. The limit of detection of the assay was 2ng which conform the minimum required performance limit (MRPL). Evaluation utility of the method indicated that all blank and spiked samples at levels below MRPL were assessed as accepted. The intensity of the green band increased whenever MG level in the extract increased; indicated that suggested mini-column technique could be used for semi-quantitative determination of MG in fish samples. The method can be used to select the questionable samples. Copyright © 2017 Elsevier Ltd. All rights reserved.

Mini-batch optimized full waveform inversion with geological constrained gradient filtering

NASA Astrophysics Data System (ADS)

Yang, Hui; Jia, Junxiong; Wu, Bangyu; Gao, Jinghuai

2018-05-01

High computation cost and generating solutions without geological sense have hindered the wide application of Full Waveform Inversion (FWI). Source encoding technique is a way to dramatically reduce the cost of FWI but subject to fix-spread acquisition setup requirement and slow convergence for the suppression of cross-talk. Traditionally, gradient regularization or preconditioning is applied to mitigate the ill-posedness. An isotropic smoothing filter applied on gradients generally gives non-geological inversion results, and could also introduce artifacts. In this work, we propose to address both the efficiency and ill-posedness of FWI by a geological constrained mini-batch gradient optimization method. The mini-batch gradient descent optimization is adopted to reduce the computation time by choosing a subset of entire shots for each iteration. By jointly applying the structure-oriented smoothing to the mini-batch gradient, the inversion converges faster and gives results with more geological meaning. Stylized Marmousi model is used to show the performance of the proposed method on realistic synthetic model.

Zone plate lenses for X-ray microscopy

NASA Astrophysics Data System (ADS)

Vladimirsky, Y.; Kern, D. P.; Chang, T. H. P.; Attwood, D. T.; Iskander, N.; Rothman, S.; McQuaide, K.; Kirz, J.; Ade, H.; McNulty, I.; Rarback, H.; Shu, D.

1988-04-01

Fresnel zone plate lenses with feature sizes as small as 50 nm have been constructed and used in the Stony Brook/NSLS scanning X-ray microscope with 3.1 nm radiation from Brookhaven's X-17 mini-undulator. The zone plates were fabricated at IBM using electron beam writing techniques, moiré pattern techniques to monitor ellipticity, and a double development/double plating technique to provide additional thickness in the central region. A spatial resolution down to 75 nm was measured in the microscope. Using these zone plates, biological images were obtained of unaltered subcellular components. The images highlight protein concentration in unsectioned, unfixed, and unstained enzymatic granules in an aqueous environment.

Effects and Implications of Mini-Lectures on Learning in First-Semester General Chemistry

ERIC Educational Resources Information Center

Toto, Joe; Booth, Kathy

2008-01-01

This study describes the efficacy of a novel tool, mini-lecture movies, in teaching Web based general chemistry. The analysis shows a marked improvement in student learning, as evidenced by a corresponding increase in homework and final exam scores. Students with access to mini-lecture movies scored 11.2% (p = 0.016) higher than students who did…

Analysis of MINIE2013 Explosion Air-Blast Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schnurr, Julie M.; Rodgers, Arthur J.; Kim, Keehoon

We report analysis of air-blast overpressure measurements from the MINIE2013 explosive experiments. The MINIE2013 experiment involved a series of nearly 70 near-surface (height-ofburst, HOB, ranging from -1 to +4 m) low-yield (W=2-20 kg TNT equivalent) chemical highexplosives tests that were recorded at local distances (230 m – 28.5 km). Many of the W and HOB combinations were repeated, allowing for quantification of the variability in air-blast features and corresponding yield estimates. We measured canonical signal features (peak overpressure, impulse per unit area, and positive pulse duration) from the air-blast data and compared these to existing air-blast models. Peak overpressure measurementsmore » showed good agreement with the models at close ranges but tended to attenuate more rapidly at longer range (~ 1 km), which is likely caused by upward refraction of acoustic waves due to a negative vertical gradient of sound speed. We estimated yields of the MINIE2013 explosions using the Integrated Yield Determination Tool (IYDT). Errors of the estimated yields were on average within 30% of the reported yields, and there were no significant differences in the accuracy of the IYDT predictions grouped by yield. IYDT estimates tend to be lower than ground truth yields, possibly because of reduced overpressure amplitudes by upward refraction. Finally, we report preliminary results on a development of a new parameterized air-blast waveform.« less

Lunar Crater Mini-Wakes: Structure, Variability, and Volatiles

NASA Technical Reports Server (NTRS)

Zimmerman, Michael I.; Jackson, T. L.; Farrell, W. M.; Stubbs, T. J.

2012-01-01

Within a permanently shadowed lunar crater the horizontal flow of solar wind is obstructed by upstream topography, forming a regional plasma mini-wake. In the present work kinetic simulations are utilized to investigate how the most prominent structural aspects of a crater mini-wake are modulated during passage of a solar storm. In addition, the simulated particle fluxes are coupled into an equivalent-circuit model of a roving astronaut,. including triboelectric charging due to frictional contact with the lunar regolith, to characterize charging of the astronaut suit during the various stages of the storm. In some cases, triboelectric charging of the astronaut suit becomes effectively perpetual, representing a critical engineering concern for roving within shadowed lunar regions. Finally, the present results suggest that wake structure plays a critical role in modulating the spatial distribution of volatiles at the lunar poles.

Accuracy of mini peak flow meters in indicating changes in lung function in children with asthma.

PubMed Central

Sly, P. D.; Cahill, P.; Willet, K.; Burton, P.

1994-01-01

OBJECTIVE--To assess whether mini flow meters used to measure peak expiratory flow can track changes in lung function and indicate clinically important changes. DESIGN--Comparison of measurements with a spirometer and different brands of mini flow meter; the meters were allocated to subjects haphazardly. SUBJECTS--12 boys with asthma aged 11 to 17 attending boarding school. MAIN OUTCOME MEASURES--Peak expiratory flow measured twice daily for three months with a spirometer and at least one of four brands of mini flow meter. RESULTS--The relation between changes in lung function measured with the spirometer and those measured with the mini flow meters was generally poor. In all, 26 episodes (range 1-3 in an individual child) of clinically important deterioration in lung function were detected from the records obtained with the spirometer. One mini flow meter detected six of 19 episodes, one detected six of 15, one detected six of 18, and one detected three of 21. CONCLUSIONS--Not only are the absolute values of peak expiratory flow obtained with mini flow meters inaccurate but the clinical message may also be incorrect. These findings do not imply that home monitoring of peak expiratory flow has no place in the management of childhood asthma but that the values obtained should be interpreted cautiously. PMID:8148680

Development of mini VSAT system

NASA Astrophysics Data System (ADS)

Lu, Shyue-Ching; Chiu, Wu-Jhy; Lin, Hen-Dao; Shih, Mu-Piao

1992-03-01

This paper presents the mini VSAT (very small aperture terminal) system, which is a low cost networking system providing economical alternatives to the business world's datacom needs. The system is designed to achieve the highest possible performance/price ratio for private VSAT networks that range from a few tens of remote terminals to large networks of several thousands remote terminals. The paper describes the system architecture, major features, hardware and software structure, access protocol and performance of the developed system.

Glaucoma Mini-Shunt Implantation After Keratoplasty.

PubMed

Ledesma-Gil, Jasbeth; García-Rodríguez, María de Los Ángeles; Gurria, Lulu U; Graue-Hernández, Enrique O; Navas, Alejandro

2017-04-01

To report the outcomes of patients who underwent miniature glaucoma shunt implantation after secondary glaucoma due to keratoplasty. Prospective study of consecutive clinical cases who underwent mini-glaucoma shunt implantation following keratoplasty. In brief, a fornix-based conjunctival flap was performed, approximately 50% thickness scleral flap. Mitomycin C 0.025% placed under Tenon's capsule. A 25-G needle created entry for mini-shunt. Ex-PRESS model P-50 was inserted. Scleral flap and conjunctiva were closed with 10-0 Nylon. STATA 8.0 and SPSS software were used for statistical analysis. Seventeen eyes of 17 patients with a mean age of 39.70 years (SD=18.33, range: 18 to 76). A total of 64.70% were male and 35.30% female. Eleven cases after penetrating keratoplasty, 3 cases after triple procedure, 2 after deep anterior lamellar keratoplasty, and 1 following endothelial keratoplasty. Most of the indications for keratoplasty were keratoconus in 9 cases (52.94%), 4 due to endothelial failure (23.52%), 3 cases of herpetic keratitis (17.64%), and 1 case of post-LASIK ectasia (5.88%). Mean preoperative intraocular pressure was 35.94 mm Hg with maximal medical therapy (SD=9.65, range: 18 to 55). Decreasing intraocular pressure to 12.76 mm Hg postoperatively (SD=2.51, range 10 to 18) (P=0.001). Mean follow-up after mini-glaucoma shunt implantation was 23.76 months (SD=8.73, range: 10 to 35 mo). Preoperative mean uncorrected distance visual acuity (UDVA) was 1.31±0.63 (20/408 Snellen) and postoperative mean UDVA was 0.85±0.40 (20/141 Snellen) (P=0.001). Preoperative mean corrected distance visual acuity (CDVA) was 0.83±0.76 (20/135 Snellen) and postoperative mean CDVA was 0.56±0.44 (20/72 Snellen) (P=0.032). Ex-PRESS miniature glaucoma shunt could be an alternative treatment in postkeratoplasty glaucoma resistant to medical treatment. This technique may be helpful, in trying to avoid corneal damage produced by conventional glaucoma procedures.

Mini-FLOTAC, an innovative direct diagnostic technique for intestinal parasitic infections: experience from the field.

PubMed

Barda, Beatrice Divina; Rinaldi, Laura; Ianniello, Davide; Zepherine, Henry; Salvo, Fulvio; Sadutshang, Tsetan; Cringoli, Giuseppe; Clementi, Massimo; Albonico, Marco

2013-01-01

Soil-transmitted helminths and intestinal protozoa infection are widespread in developing countries, yet an accurate diagnosis is rarely performed. The aim of this study was to evaluate the recently developed mini-FLOTAC method and to compare with currently more widely used techniques for the diagnosis of intestinal parasitic infections in different settings. The study was carried out in Dharamsala, Himachal Pradesh, India, and in Bukumbi, Tanzania. A total of 180 pupils from two primary schools had their stool analyzed (n = 80 in Dharamsala and n = 100 in Bukumbi) for intestinal parasitic infections with three diagnostic methods: direct fecal smear, formol-ether concentration method (FECM) and mini-FLOTAC. Overall, 72% of the pupils were positive for any intestinal parasitic infection, 24% carried dual infections and 11% three infections or more. The most frequently encountered intestinal parasites were Entamoeba coli, Entamoeba histolytica/dispar, Giardia intestinalis, hookworm, (and Schistosoma mansoni, in Tanzania). Statistically significant differences were found in the detection of parasitic infections among the three methods: mini-FLOTAC was the most sensitive method for helminth infections (90% mini-FLOTAC, 60% FECM, and 30% direct fecal smear), whereas FECM was most sensitive for intestinal protozoa infections (88% FECM, 70% direct fecal smear, and 68% mini-FLOTAC). We present the first experiences with the mini-FLOTAC for the diagnosis of intestinal helminths and protozoa. Our results suggest that it is a valid, sensitive and potentially low-cost alternative technique that could be used in resource-limited settings--particularly for helminth diagnosis.

Controller Evaluation of Initial Data Link Air Traffic Control Services, Mini Study 1, Volume 2

DOT National Transportation Integrated Search

1988-09-01

This report details the results of Mini Study 1. This mini study was conducted : at the Federal Aviation Administration (FAA) Technical Center utilizing the Data : Link testbed. Initial Data Link air traffic control services were evaluated : under pa...

Preliminary study on weapon grade uranium utilization in molten salt reactor miniFUJI

NASA Astrophysics Data System (ADS)

Aji, Indarta Kuncoro; Waris, A.

2014-09-01

Preliminary study on weapon grade uranium utilization in 25MWth and 50MWth of miniFUJI MSR (molten salt reactor) has been carried out. In this study, a very high enriched uranium that we called weapon grade uranium has been employed in UF4 composition. The 235U enrichment is 90 - 95 %. The results show that the 25MWth miniFUJI MSR can get its criticality condition for 1.56 %, 1.76%, and 1.96% of UF4 with 235U enrichment of at least 93%, 90%, and 90%, respectively. In contrast, the 50 MWth miniFUJI reactor can be critical for 1.96% of UF4 with 235U enrichment of at smallest amount 95%. The neutron spectra are almost similar for each power output.

Controller Evaluation of Initial Data Link Air Traffic Control Services, Mini Study 1, Volume 1

DOT National Transportation Integrated Search

1988-09-01

This report details the results of Mini Study 1. This mini study was conducted : at the Federal Aviation (FAA) Technical Center utilizing the Data Link testbed. : Initial Data Link air traffic control services were under part task simulation : condit...

The Mini-Calorimeter on-board AGILE: The first year in space

NASA Astrophysics Data System (ADS)

Marisaldi, M.; Labanti, C.; Fuschino, F.; Galli, M.; Argan, A.; Bulgarelli, A.; Di Cocco, G.; Gianotti, F.; Tavani, M.; Trifoglio, M.; Trois, A.

2009-04-01

AGILE, the Italian space mission dedicated to gamma-ray and hard-X astrophysics, was successfully launched on 23rd April 2007 and is currently fully operative. The Mini-Calorimeter (MCAL) on-board the AGILE satellite is a scintillation detector made of 20 kg of segmented CsI(Tl) scintillator with photodiode readout with a total geometrical area of 1400 cm2. MCAL can work both as a slave of the AGILE Silicon tracker and as an independent detector for gamma-ray bursts (GRB) detection in the 300 keV - 100 MeV energy range. Despite its limited thickness, due to weight constraints, MCAL has proven to successfully self-trigger GRBs at MeV energies providing photon-by-photon data with less than 2 μs time resolution and almost all-sky detection capabilities. The instrument design and characteristics, as well as the in-flight performance after one year of operation in space and the scientific results obtained so far are reviewed and discussed.

Mini-FLOTAC and Kato-Katz: helminth eggs watching on the shore of Lake Victoria.

PubMed

Barda, Beatrice; Zepherine, Henry; Rinaldi, Laura; Cringoli, Giuseppe; Burioni, Roberto; Clementi, Massimo; Albonico, Marco

2013-07-31

One of the challenges for monitoring helminth control programmes based on preventive chemotherapy is the lack of a copro-parasitological gold-standard method that combines good sensitivity with quantitative performance, low cost, and easy-to-learn technique.The aim of our study was to evaluate and compare, the WHO recommended quantitative diagnostic technique (Kato-Katz) and the Mini-FLOTAC. Mini-FLOTAC is an innovative method based on floatation of helminths eggs with two different solutions (FS2 and FS7) using a close system (Fill-FLOTAC) with 5% fixative. Kato-Katz was performed following WHO recommendation. The study was carried out in a rural part of Tanzania, close to Lake Victoria, where the laboratory facilities are fairly scarce, and the basic technique used in the local laboratory (direct smear) was taken as reference standard. 201 children were screened for intestinal helminths and 91% of them were found to be positive. The agreement among the three techniques was calculated with k Cohen coefficient and was fairly good (k = 0.4), although the Mini-FLOTAC results were more sensitive for hookworm (98%) with FS2, and for S.mansoni (90%) with FS7 followed by Kato-Katz (91% and 60% respectively) and direct smear (30% and 10% respectively). A good agreement was found between Mini-FLOTAC and Kato-Katz (k = 0.81) with FS7 (k = 0.76) for hookworm diagnosis and a fairly good one for S.mansoni diagnosis (k = 0.5). For both infections we had a poor agreement between the two quantitative techniques and the direct smear (k<0.3). Kato-Katz diagnosed a higher number of eggs (calculated by arithmetic mean) both for hookworm (455 vs 424 EPG) and for S.mansoni (71 vs 58 EPG) compared with the Mini-FLOTAC, but the differences were not significant (p = 0.4). Mini-FLOTAC is a promising technique, comparable and as sensitive as the Kato-Katz, which is the recommended method in intestinal helminthology for monitoring helminth control programmes. A comparative

Surgical positioning of orthodontic mini-implants with guides fabricated on models replicated with cone-beam computed tomography.

PubMed

Kim, Seong-Hun; Choi, Yong-Suk; Hwang, Eui-Hwan; Chung, Kyu-Rhim; Kook, Yoon-Ah; Nelson, Gerald

2007-04-01

This article illustrates a new surgical guide system that uses cone-beam computed tomography (CBCT) images to replicate dental models; surgical guides for the proper positioning of orthodontic mini-implants were fabricated on the replicas, and the guides were used for precise placement. The indications, efficacy, and possible complications of this method are discussed. Patients who were planning to have orthodontic mini-implant treatment were recruited for this study. A CBCT system (PSR 9000N, Asahi Roentgen, Kyoto, Japan) was used to acquire virtual slices of the posterior maxilla that were 0.1 to 0.15 mm thick. Color 3-dimensional rapid prototyping was used to differentiate teeth, alveolus, and maxillary sinus wall. A surgical guide for the mini-implant was fabricated on the replica model. Proper positioning for mini-implants on the posterior maxilla was determined by viewing the CBCT images. The surgical guide was placed on the clinical site, and it allowed precise pilot drilling and accurate placement of the mini-implant. CBCT imaging allows remarkably lower radiation doses and thinner acquisition slices compared with medical computed tomography. Virtually reproduced replica models enable precise planning for mini-implant positions in anatomically complex sites.

Controller Evaluation of Initial Data Link Air Traffic Control Services: Mini Study 2 Volume II

DOT National Transportation Integrated Search

1989-03-01

This report details the results of Mini Study 2. This Mini Study was conducted at the Federal Aviation Administration (FAA) Technical Center utilizing the Data Link test bed. Initial Data Link air traffic control services were evaluated under part ta...

Controller Evaluation of Initial Data Link Air Traffic Control Services: Mini Study 2 Volume I

DOT National Transportation Integrated Search

1989-03-01

This report details the results of Mini Study 2. This Mini Study was conducted at the Federal Aviation Administration (FAA) Technical Center utilizing the Data Link test bed. Initial Data Link air traffic control services were evaluated under part ta...

Effect of MeJA treatment on polyamine, energy status and anthracnose rot of loquat fruit.

PubMed

Cao, Shifeng; Cai, Yuting; Yang, Zhenfeng; Joyce, Daryl C; Zheng, Yonghua

2014-02-15

The effect of methyl jasmonate (MeJA) on changes in polyamines content and energy status and their relation to disease resistance was investigated. Freshly harvested loquat fruit were treated with 10 μmol l(-1) MeJA and wound inoculated with Colletotrichum acutatum spore suspension (1.0 × 10(5) spores ml(-1)) after 24h, and then stored at 20 °C for 6 days. MeJA treatment significantly reduced decay incidence. MeJA treated fruit manifested higher contents of polyamines (putrescine, spermidine and spermine) compared with the control fruit, during storage. MeJA treatment also maintained higher levels of adenosine triphosphate, and suppressed an increase in adenosine monophosphate content in loquat fruit. These results suggest that MeJA treatment may inhibit anthracnose rot by increasing polyamine content and maintaining the energy status. Copyright © 2013. Published by Elsevier Ltd.

Comparison of Head Scatter Factor for 6MV and 10MV flattened (FB) and Unflattened (FFF) Photon Beam using indigenously Designed Columnar Mini Phantom.

PubMed

Ashokkumar, Sigamani; Nambi Raj, N Arunai; Sinha, Sujit Nath; Yadav, Girigesh; Thiyagarajan, Rajesh; Raman, Kothanda; Mishra, Manindra Bhushan

2014-07-01

To measure and compare the head scatter factor for flattened (FB) and unflattened (FFF) of 6MV and 10MV photon beam using indigenously designed mini phantom. A columnar mini phantom was designed as recommended by AAPM Task Group 74 with low and high atomic number materials at 10 cm (mini phantom) and at approximately twice the depth of maximum dose water equivalent thickness (brass build-up cap). Scatter in the accelerator (Sc) values of 6MV-FFF photon beams are lesser than that of the 6MV-FB photon beams (0.66-2.8%; Clinac iX, 2300CD) and (0.47-1.74%; True beam) for field sizes ranging from 10 × 10 cm(2) to 40 × 40 cm(2). Sc values of 10MV-FFF photon beams are lesser (0.61-2.19%; True beam) than that of the 10MV-FB photons beams for field sizes ranging from 10 × 10 cm(2) to 40 × 40 cm(2). The SSD had no influence on head scatter for both flattened and unflattened beams and irrespective of head design of the different linear accelerators. The presence of field shaping device influences the Sc values. The collimator exchange effect reveals that the opening of the upper jaw increases Sc irrespective of FB or FFF photon beams and different linear accelerators, and it is less significant in FFF beams. Sc values of 6MV-FB square field were in good agreement with that of AAPM, TG-74 published data for Varian (Clinac iX, 2300CD) accelerator. Our results confirm that the removal of flattening filter decreases in the head scatter factor compared to flattened beam. This could reduce the out-of-field dose in advanced treatment delivery techniques.

Comparison of Head Scatter Factor for 6MV and 10MV flattened (FB) and Unflattened (FFF) Photon Beam using indigenously Designed Columnar Mini Phantom

PubMed Central

Ashokkumar, Sigamani; Nambi Raj, N Arunai; Sinha, Sujit Nath; Yadav, Girigesh; Thiyagarajan, Rajesh; Raman, Kothanda; Mishra, Manindra Bhushan

2014-01-01

To measure and compare the head scatter factor for flattened (FB) and unflattened (FFF) of 6MV and 10MV photon beam using indigenously designed mini phantom. A columnar mini phantom was designed as recommended by AAPM Task Group 74 with low and high atomic number materials at 10 cm (mini phantom) and at approximately twice the depth of maximum dose water equivalent thickness (brass build-up cap). Scatter in the accelerator (Sc) values of 6MV-FFF photon beams are lesser than that of the 6MV-FB photon beams (0.66-2.8%; Clinac iX, 2300CD) and (0.47-1.74%; True beam) for field sizes ranging from 10 × 10 cm2 to 40 × 40 cm2. Sc values of 10MV-FFF photon beams are lesser (0.61-2.19%; True beam) than that of the 10MV-FB photons beams for field sizes ranging from 10 × 10 cm2 to 40 × 40 cm2. The SSD had no influence on head scatter for both flattened and unflattened beams and irrespective of head design of the different linear accelerators. The presence of field shaping device influences the Sc values. The collimator exchange effect reveals that the opening of the upper jaw increases Sc irrespective of FB or FFF photon beams and different linear accelerators, and it is less significant in FFF beams. Sc values of 6MV-FB square field were in good agreement with that of AAPM, TG-74 published data for Varian (Clinac iX, 2300CD) accelerator. Our results confirm that the removal of flattening filter decreases in the head scatter factor compared to flattened beam. This could reduce the out-of-field dose in advanced treatment delivery techniques. PMID:25190997

The Mini-Patt Approach for Individualizing Instruction.

ERIC Educational Resources Information Center

Jenkins, Jimmy R.; Krockover, Gerald H.

A method is proposed which is said to allow elementary and secondary teachers to prepare 30-minute audio-tutorial tapes in one to three hours. A list of materials needed is provided, and the six-step procedure outlined. More than 300 Mini-Patt tapes are said to have been produced for use from elementary

Mini-Enterprise Projects: Friendship, Business and Learning

ERIC Educational Resources Information Center

Riese, Hanne

2013-01-01

This article discusses how the mini-enterprise (ME) approach (Young Enterprise) can be understood as a tool for helping to achieve policy goals set for entrepreneurship. Analysis of 12 semi-structured interviews with 17-year-old students shows how social capital from friendship relations constitutes norms for interaction in MEs. To some extent,…

X-Ray Emission from Ultraviolet Luminous Galaxies and Lyman Break Galaxies

NASA Technical Reports Server (NTRS)

Hornschemeier, Ann; Ptak, A. F.; Salim, S.; Heckman, T. P.; Overzier, R.; Mallery, R.; Rich, M.; Strickland, D.; Grimes, J.

2009-01-01

We present results from an XMM mini-survey of GALEX-selected Ultraviolet-Luminous Galaxies (UVLGs) that appear to include an interesting subset that are analogs to the distant (3X-ray emission of LBGs appear to be broadly similar to that of galaxies in the local Universe, possibly indicating similarity in the production of accreting binaries over large evolutionary timescales in the Universe. We have detected luminous X-ray emission from one UVLG that permits basic X-ray spectroscopic analysis, and have direct X-ray constraints on a total of 6 UVLGs. We find evidence for likely large scatter in the assumed X-ray/star-formation rate relation for LBGs.

Graphing Calculator Mini Course

NASA Technical Reports Server (NTRS)

Karnawat, Sunil R.

1996-01-01

The "Graphing Calculator Mini Course" project provided a mathematically-intensive technologically-based summer enrichment workshop for teachers of American Indian students on the Turtle Mountain Indian Reservation. Eleven such teachers participated in the six-day workshop in summer of 1996 and three Sunday workshops in the academic year. The project aimed to improve science and mathematics education on the reservation by showing teachers effective ways to use high-end graphing calculators as teaching and learning tools in science and mathematics courses at all levels. In particular, the workshop concentrated on applying TI-82's user-friendly features to understand the various mathematical and scientific concepts.

Outcomes of Mini vs Roux-en-Y gastric bypass: A meta-analysis and systematic review.

PubMed

Wang, Fu-Gang; Yan, Wen-Mao; Yan, Ming; Song, Mao-Min

2018-05-10

Mini gastric bypass has been proved to be capable of achieving excellent metabolic results by numerous published studies. Compared to Roux-en-Y gastric bypass, mini gastric bypass is a technically simpler and reversible procedure. However, comparative outcomes of the effectiveness between Mini gastric bypass and Roux-en-Y gastric bypass remain unclear. A systematic literature search was performed in Pubmed, Embase, Cochrane library from inception to February 9, 2018. For assessment of method quality, NOS (Newcastle-Ottawa Scale) and Cochrane Collaboration's tool for assessing risk of bias were used for cohort study and randomized controlled trials, respectively. The meta-analysis was performed by RevMan 5.3 software. 10 cohort studies and 1 randomized controlled trial was included in our meta-analysis. The method quality of the 10 cohort studies was proved as high quality according to the Newcastle-Ottawa Scale. The randomized controlled trial was proved to have a low risk of bias according to Cochrane Collaboration's assessment. Patients receiving mini-gastric bypass had multiple advantageous indexes as compared with patients receiving Roux-en-Y gastric bypass. Examples include: a higher 1-year EWL% (P < 0.05), higher 2-year EWL% (P < 0.05), higher type 2 diabetes mellitus remission rate, as well as a shorter operation time (P < 0.05). No significant statistical difference was observed in hypertension remission rate, mortality, leakage rate, GERD rate, or hospital stay between mini gastric bypass and Roux-en-Y gastric bypass. Mini gastric bypass seems to be a simpler procedure with a better weight reduction effect. This seems to also be the case regarding remission rates of type 2 diabetes mellitus when using Mini gastric bypass in comparison to Roux-en-Y gastric bypass. A small sample size and biased data may have influenced the stability of our results. In light of this, surgeons should treat our results in a conservative way. Larger sample size and

Comparison of flexible ureterorenoscopy and mini-percutaneous nephrolithotomy in treatment of lower calyceal stones smaller than 2 cm.

PubMed

Akbulut, Fatih; Kucuktopcu, Onur; Kandemir, Emre; Sonmezay, Erkan; Simsek, Abdulmuttalip; Ozgor, Faruk; Binbay, Murat; Muslumanoglu, Ahmet Yaser; Gurbuz, Gokhan

2016-01-01

To compare the outcomes of flexible ureterorenoscopy (F-URS) and mini-percutaneous nephrolithotomy (mini-PNL) in the treatment of lower calyceal stones smaller than 2 cm. Patients who underwent F-URS and mini-PNL for the treatment of lower calyceal stones smaller than 2 cm between March 2009 and December 2014 were retrospectively evaluated. Ninety-four patients were divided into two groups by treatment modality: F-URS (Group 1: 63 patients) and mini-PNL (Group 2: 31 patients). All patients were preoperatively diagnosed with intravenous pyelography or computed tomography. Success rates for F-URS and mini-PNL at postoperative first month were 85.7% and 90.3%, respectively. Operation time, fluoroscopy time, and hospitalization time for F-URS and mini-PNL patients were 44.40 min, 2.9 min, 22.4 h, and 91.9 min, 6.4 min, and 63.8 h, respectively. All three parameters were significantly shorter among the F-URS group (p < 0.001). Postoperative hemoglobin drop was significantly lower in F-URS group compared to mini-PNL group (0.39 mg/dL vs. 1.15 mg/dL, p = 0.001). A comparison of complications according to the Clavien classification demonstrated significant differences between the groups (p = 0.001). More patients in the F-URS groups require antibiotics due to urinary tract infection, and more patients in the mini-PNL group required ureteral double J catheter insertion under general anesthesia. Although both F-URS and mini-PNL have similar success rates for the treatment of lower calyceal stones, F-URS appears to be more favorable due to shorter fluoroscopy and hospitalization times; and lower hemoglobin drops. Multicenter and studies using higher patient volumes are needed to confirm these findings.

Support for designing waste sorting systems: A mini review.

PubMed

Rousta, Kamran; Ordoñez, Isabel; Bolton, Kim; Dahlén, Lisa

2017-11-01

This article presents a mini review of research aimed at understanding material recovery from municipal solid waste. It focuses on two areas, waste sorting behaviour and collection systems, so that research on the link between these areas could be identified and evaluated. The main results presented and the methods used in the articles are categorised and appraised. The mini review reveals that most of the work that offered design guidelines for waste management systems was based on optimising technical aspects only. In contrast, most of the work that focused on user involvement did not consider developing the technical aspects of the system, but was limited to studies of user behaviour. The only clear consensus among the articles that link user involvement with the technical system is that convenient waste collection infrastructure is crucial for supporting source separation. This mini review reveals that even though the connection between sorting behaviour and technical infrastructure has been explored and described in some articles, there is still a gap when using this knowledge to design waste sorting systems. Future research in this field would benefit from being multidisciplinary and from using complementary methods, so that holistic solutions for material recirculation can be identified. It would be beneficial to actively involve users when developing sorting infrastructures, to be sure to provide a waste management system that will be properly used by them.

Macro, mini, micro and nano (M(sup 3)N) technologies for the future

NASA Technical Reports Server (NTRS)

Friedrich, Craig R.; Warrington, Robert O.; Gao, Robert X.; Lin, Gang

1993-01-01

Microelectromechanical systems (MEMS), micro systems technologies (MST), and micromanufacturing are relatively recent phrases or acronyms that have become synonymous with the design, development, and manufacture of 'micro' devices and systems. Micromanufacturing encompasses MEMS or MST and, in addition, includes all of the processes involved in the production of micro things. Integration of mechanical and electrical components, including built-in computers, can be formed into systems which must be connected to the macroworld. Macro, mini, micro, and nano technologies are all a part of MEMS or micromanufacturing. At this point in the development of the technology, it is becoming apparent that mini systems, with micro components, could very well be the economic drivers of the technology for the foreseeable future. Initial research in the fabrication of microdevices using IC processing technology took place over thirty years ago. Anisotropic etching of silicon was used to produce piezoresistive diaphragms. Since the early 60's, there has been gradual progress in MEMS until the early 1980's when worldwide interest in the technology really started to develop. During this time high aspect ratio micromachining using x rays was started in Germany. In 1987 the concept of a 'silicon micromechanics foundry' was proposed. Since then the interest in the U.S., Germany, and Japan has increased to the point where hundreds of millions of dollars of research monies are being funneled into the technology (at least in Germany and Japan) and the technology has been classified as critical or as a technology or national importance by the U.S. government.

Toxicological Assessment of ISS Air Quality: SpaceX-2 First Ingress

NASA Technical Reports Server (NTRS)

Meyers, Valerie

2013-01-01

One mini-grab sample container (M-GSC) was collected by crew members onboard ISS during first ingress into SpaceX-2 on March 3, 2013, three days after late cargo loading and a pre-launch clean air purge. Recoveries of the three surrogate standards from the m-GSC were: 13C-acetone, 97%; fluorobenzene, 95%; and chlorobenzene, 68%.

Energy-Water Nexus Relevant to Baseload Electricity Source Including Mini/Micro Hydropower Generation

NASA Astrophysics Data System (ADS)

Fujii, M.; Tanabe, S.; Yamada, M.

2014-12-01

Water, food and energy is three sacred treasures that are necessary for human beings. However, recent factors such as population growth and rapid increase in energy consumption have generated conflicting cases between water and energy. For example, there exist conflicts caused by enhanced energy use, such as between hydropower generation and riverine ecosystems and service water, between shale gas and ground water, between geothermal and hot spring water. This study aims to provide quantitative guidelines necessary for capacity building among various stakeholders to minimize water-energy conflicts in enhancing energy use. Among various kinds of renewable energy sources, we target baseload sources, especially focusing on renewable energy of which installation is required socially not only to reduce CO2 and other greenhouse gas emissions but to stimulate local economy. Such renewable energy sources include micro/mini hydropower and geothermal. Three municipalities in Japan, Beppu City, Obama City and Otsuchi Town are selected as primary sites of this study. Based on the calculated potential supply and demand of micro/mini hydropower generation in Beppu City, for example, we estimate the electricity of tens through hundreds of households is covered by installing new micro/mini hydropower generation plants along each river. However, the result is based on the existing infrastructures such as roads and electric lines. This means that more potentials are expected if the local society chooses options that enhance the infrastructures to increase micro/mini hydropower generation plants. In addition, further capacity building in the local society is necessary. In Japan, for example, regulations by the river law and irrigation right restrict new entry by actors to the river. Possible influences to riverine ecosystems in installing new micro/mini hydropower generation plants should also be well taken into account. Deregulation of the existing laws relevant to rivers and

Impact of a Ground Network of Miniaturized Laser Heterodyne Radiometers (mini-LHRs) on Global Carbon Flux Estimates

NASA Astrophysics Data System (ADS)

DiGregorio, A.; Wilson, E. L.; Palmer, P. I.; Mao, J.; Feng, L.

2017-12-01

We present the simulated impact of a small (50 instrument) ground network of NASA Goddard Space Flight Center's miniaturized laser heterodyne radiometer (mini-LHR), a small, low cost ( 50k), portable, and high precision CH4 and CO2 measuring instrument. Partnered with AERONET as a non-intrusive accessory, the mini-LHR is able to leverage the 500+ instrument AERONET network for rapid network deployment and testing, and simultaneously retrieve co-located aerosol data, an important input for sattelite measurements. This observing systems simulation experiment (OSSE) uses the 3-D GEOS-Chem chemistry transport model and 50 strategically selected sites to model flux estimate uncertainty reduction of both TCCON and mini-LHR instruments. We found that 50 mini-LHR sites are capable of improving global uncertainty by up to 70%, with local improvements in the Southern Hemisphere reaching to 90%. Our studies show that addition of the mini-LHR to current ground networks will play a major role in reduction of global carbon flux uncertainty.

Development of the Mini-Assisting Hand Assessment: evidence for content and internal scale validity.

PubMed

Greaves, Susan; Imms, Christine; Dodd, Karen; Krumlinde-Sundholm, Lena

2013-11-01

To describe the development of the Mini-Assisting Hand Assessment (Mini-AHA) for children with signs of unilateral cerebral palsy (CP) aged 8 to 18 months, and evaluate aspects of content and internal scale validity. The ability of the video-recorded Mini-AHA play session to provoke bimanual performance in children with unilateral CP and typical development was evaluated. Original AHA test items were examined for their suitability for younger children and possible new items were generated. Data from 108 assessments of children with unilateral CP (86 children, 53 males, 33 females; mean age 13 mo, SD 3 mo, range 8-18 mo) were entered into a Rasch measurement model analysis to evaluate internal scale validity. A Spearman's correlation analysis explored the relationship between age and ability measures for children with unilateral CP. The frequency of maximum scores in 40 children with typical development (22 males, 18 females; mean age 12 mo, SD 3 mo) was examined. The Mini-AHA play session provoked bimanual responses in typically developing children 99% of the time. Person and item fit criteria established 20 items for the scale. The resultant unidimensional scale also demonstrated excellent discriminative features through high separation reliability. The item calibration values covered the range of person ability measures well. Age was not related to the ability measures for children with unilateral CP (rs =0.178). All children with typical development achieved maximum scores. Accumulated evidence shows that the Mini-AHA validly measures use of the affected hand during bimanual performance for children with unilateral CP aged 8 to 18 months. The Mini-AHA has the potential to be a useful assessment to evaluate functional hand use and the effects of intervention in an age group when potential for change is high. © 2013 Mac Keith Press.

Mini-Course on Consumer Education Teacher's Guide.

ERIC Educational Resources Information Center

Hawaii State Dept. of Education, Honolulu. Office of Instructional Services.

Consumer Education is a mini-course designed for all seniors in high school. It was developed on the premise that a student needs to evolve his own value system, develop a sound decision-makingprocedure based upon his values, evaluate alternatives in the marketplace and get the best buys for his money, understand his rights and responsibilities as…

Use of Mini-Grant to Disseminate Evidence-Based Interventions for Cancer Prevention and Control.

PubMed

Kegler, Michelle C; Carvalho, Michelle L; Ory, Marcia; Kellstedt, Deb; Friedman, Daniela B; McCracken, James Lyndon; Dawson, Glenna; Fernandez, Maria

2015-01-01

Mini-grants are an increasingly common tool for engaging communities in evidence-based interventions for promoting public health. This article describes efforts by 4 Centers for Disease Control and Prevention/National Cancer Institute-funded Cancer Prevention and Control Research Network centers to design and implement mini-grant programs to disseminate evidence-based interventions for cancer prevention and control. This article also describes source of evidence-based interventions, funding levels, selection criteria, time frame, number and size of grants, types of organizations funded, selected accomplishments, training and technical assistance, and evaluation topics/methods. Grant size ranged from $1000 to $10 000 (median = $6250). This mini-grant opportunity was characterized by its emphasis on training and technical assistance for evidence-based programming and dissemination of interventions from National Cancer Institute's Research-Tested Intervention Programs and Centers for Disease Control and Prevention's Guide to Community Preventive Services. All projects had an evaluation component, although they varied in scope. Mini-grant processes described can serve as a model for organizations such as state health departments working to bridge the gap between research and practice.

Opto-box: Optical modules and mini-crate for ATLAS pixel and IBL detectors

NASA Astrophysics Data System (ADS)

Bertsche, David

2016-11-01

The opto-box is a custom mini-crate for housing optical modules which process and transfer optoelectronic data. Many novel solutions were developed for the custom design and manufacturing. The system tightly integrates electrical, mechanical, and thermal functionality into a small package of size 35×10x8 cm3. Special attention was given to ensure proper shielding, grounding, cooling, high reliability, and environmental tolerance. The custom modules, which incorporate Application Specific Integrated Circuits, were developed through a cycle of rigorous testing and redesign. In total, fourteen opto-boxes have been installed and loaded with modules on the ATLAS detector. They are currently in operation as part of the LHC run 2 data read-out chain. This conference proceeding is in support of the poster presented at the International Conference on New Frontiers in Physics (ICNFP) 2015 [1].

Meeting international standards: a cultural approach in implementing the mini-CEX effectively in Indonesian clerkships.

PubMed

Suhoyo, Yoyo; Schönrock-Adema, Johanna; Rahayu, Gandes Retno; Kuks, Jan B M; Cohen-Schotanus, Janke

2014-10-01

Abstract Background: Medical schools all over the world try to adapt their programs to meet international standards. However, local culture might hamper innovation attempts. To describe challenges in implementing the mini-CEX in Indonesia and investigate its effect on students' clinical competence. The study was conducted in the Internal Medicine and Neurology departments of the Universitas Gadjah Mada, Indonesia. Implementing the mini-CEX into the existing curriculum, while taking the Indonesian culture into account, implied a shift from group to individual feedback. We compared students' final clinical competence before (Internal Medicine n = 122, Neurology n = 183) and after (n = 183 and 186, respectively) the implementation of the mini-CEX, using a modified Objective Structured Long Examination Record (OSLER). The Mann-Whitney test was used to analyze the data. We took power distance and individualism into account to facilitate the implementation process. After implementing the mini-CEX, the OSLER results were significant higher in Internal Medicine (p < 0.05). However, no differences were found in Neurology. By managing the innovation process carefully and taking culture and local context into account, the mini-CEX can be implemented without changing the underlying concept. The shift from group to individual feedback seems to have a positive effect on student learning.

Case Study: Mini-Case Studies: Small Infusions of Active Learning for Large-Lecture Courses

ERIC Educational Resources Information Center

Carloye, Lisa

2017-01-01

In this article, the author introduces the usage of case studies to be an excellent method for engaging students through stories. The author notes she developed a series of mini-case studies that can be implemented, with a little advance preparation, within a 10- to 15-minute window during lecture. What makes them "mini" case studies?…

Maxillary anterior en masse retraction using different antero-posterior position of mini screw: a 3D finite element study.

PubMed

Hedayati, Zohreh; Shomali, Mehrdad

2016-12-01

Nowadays, mini screws are used in orthodontic tooth movement to obtain maximum or absolute anchorage. They have gained popularity among orthodontists for en masse retraction of anterior teeth after first premolar extraction in maximum anchorage cases. The purpose of this study was to determine the type of anterior tooth movement during the time when force was applied from different mini screw placements to the anterior power arm with various heights. A finite element method was used for modeling maxillary teeth and bone structure. Brackets, wire, and hooks were also designed for modeling. Two appropriate positions for mini screw in the mesial and distal of the second premolar were designed as fixed nodes. Forces were applied from the mini screw to four different levels of anterior hook height: 0, 3, 6, and 9 mm. Initial tooth movement in eight different conditions was analyzed and calculated with ANSYS software. Rotation of anterior dentition was decreased with a longer anterior power arm and the mesial placement of the mini screw. Bodily movements occurred with the 9-mm height of the power arm in both mini screw positions. Intrusion or extrusion of the anterior teeth segment depended on the level of the mini screw and the edge of the power arm on the Z axis. According to the findings of this study, the best control in the sagittal plane during anterior en masse retraction was achieved by mesial placement of the mini screw and the 9-mm height of the anterior power arm. Where control in the vertical plane was concerned, distal placement of the mini screw with the 6-mm power arm height had minimum adverse effect on anterior dentition.

The clinical and radiological results of arthroscopic versus arthroscopy assisted mini-open repair of rotator cuff tears

PubMed Central

Özcan, Muhammed Sefa; Sezer, Hasan Basri; Eren, Osman Tuğrul; Armağan, Raffi; Kanar, Muharrem

2017-01-01

In this study we reported retrospectively the comperative clinical and radiological results of the two most common surgical procedures in rotator cuff tear repair of shoulder, the golden standart arthroscopic and alternative arthroscopically assisted mini-open surgery. We included 58 patients who admitted to our clinic for rotator cuff tear and treated surgically between january 2013 and august 2015. The two groups were composed of arthroscopically treated 29 patients and 29 patients who were treated with arthroscopically assisted mini open surgery. The arthroscopy group included 18 females and 11 males, the mini-open group included 10 females and 19 males. The mean age was 56,0 (39,0-73,0) years, in arthroscopic and 55,0 (40,0-70,0) years in mini-open surgery group. 6 patients in the arthroscopy group(20,7%) and 10 patients in the mini-open group(34,5%) were defining trauma before the beginning of their complaints. The postoperative follow up was 28,9 months in arthroscopy group and 22,6 months in the mini-open surgery group. Preoperative physical or medical treatments were documented. Any additional surgical procedures like biceps long head tenotomy, subacromial decompression and bursectomy were also noted. Patients were evaluated with ASES and Constant shoulder scales before and after the surgery. Patients were evaluated radiologically with MRI at the last follow up for healing and tendon quality. The type 2 acromion was the dominant in both groups constituting the 44,8% of the total number of patients. 24 (82,8%)patients in the arthroscopically treated patients and 18(62,1%) patients in the mini-open group were undergone at least one of the additional surgical treatments. The mean length of the surgical scar was 3,4(3-5) cm in mini open group. None of the patients complained of the surgical scar. 16 patients in the arthroscopy group and 17 patients in the mini-open group had supraspinatus tendon pathology(either tear or degeneration) in the MRI control at the

Trapped magnetic field of a mini-bulk magnet using YBaCuO at 77 K

NASA Astrophysics Data System (ADS)

Fujimoto, Hiroyuki; Kamijo, Hiroki

2001-09-01

Melt-processed rare earth (RE)123 superconductors have a high Jc at 77 K and high magnetic field. Solidification processes for producing (L)RE123 superconductors and pinning centers in the (L)RE123 matrix are effective for obtaining high Jc, leading to high-field application as a superconducting quasi-permanent bulk magnet with the liquid nitrogen refrigeration. One of the promising applications is a superconducting magnet for the magnetically levitated train. We fabricated a mini-superconducting bulk magnet of 200×100 mm2, consisting of 18 bulks, which are a square 33 mm on a side and 10 mm in thickness, and magnetized the mini-magnet by field cooling. The mini-magnet showed the trapped magnetic field of larger than 0.1 T on the surface of the outer vessel of the magnet. The present preliminary study discusses trapped magnetic field properties of the mini-bulk magnet using YBaCuO superconductors at 77 K.

Observation of rat's colon polyps in real time by mini-endoscopy and raman spectroscopy

NASA Astrophysics Data System (ADS)

Andriana, Bibin Bintang; Mahardika, Anggara; Taketani, Akihiro; Sato, Hidetoshi

2018-02-01

Colorectal adenoma (CA) is a disease caused by various factors (such as genetic factors or environmental exposures). The appearance of colon polyp (CP) within colorectal might indicate the hint of CA development. Ball-lens hollow fiber Raman probe (BHRP) may has a high capability for detection of CA in living experimental animal and have already tested to rat's CP in this study, which was designed to collaborate between BHRP with mini-endoscopy to observe the biochemical alteration within normal colon tissue and rat's colon polyps in real time. BHRP and mini-endoscopy can distinguish the differences in their finger print spectra and make pictures the control and CP in the real time. At the first step, the real situation of normal colon and Rat's CP were washed by saline and observed with mini-endoscopy. BHRP was introduced to Dextran sodium sulphate (DSS)-induced Rat's CP to detect some of biochemical alteration. The main purpose of this study was to introduce mini-endoscopy to guide the BHRP for diagnosing of CP in real time and to compare it with spectra of normal colon (control group) in living rat. As the result, BHRP can provide the differences in band of control and CP group, which can inform that the biochemical of normal and CP has changed. As a major parameter to distinct normal and CP tissue were phosphatidylinositol, phosphodiester group, lipid, and collagen. Mini endoscopy and BHRP is very sensitive devices for diagnosing of CP in real time.

Vaporization inside a mini microfin tube: experimental results and modeling

NASA Astrophysics Data System (ADS)

Diani, A.; Rossetto, L.

2015-11-01

This paper proposes a comparison among the common R134a and the extremely low GWP refrigerant R1234yf during vaporization inside a mini microfin tube. This microfin tube has an internal diameter of 2.4 mm, it has 40 fins, with a fin height of 0.12 mm. Due to the high heat transfer coefficients shown by this tube, this technology can lead to a refrigerant charge reduction. Tests were run in the Heat Transfer in Micro Geometries Lab of the Dipartimento di Ingegneria Industriale of the Università di Padova. Mass velocities range between 375 and 940 kg m-2 s-1, heat fluxes from 10 to 50 kW m-2, vapour qualities from 0.10 to 0.99, at a saturation temperature of 30°C. The comparison among the two fluids is proposed at the same operating conditions, in order to highlight the heat transfer and pressure drop differences among the two refrigerants. In addition, two correlations are proposed to estimate the heat transfer coefficient and frictional pressure drop during refrigerant flow boiling inside mini microfin tubes. These correlations well predict the experimental values, and thus they can be used as a useful tool to design evaporators based on these mini microfin tubes.

The Mini Dark Room from Holywell High

ERIC Educational Resources Information Center

Lane, Frank

2011-01-01

The mini dark room from Holywell High School costs nothing to make and has a construction time of 10 min. In spite of progress, or perhaps because of it, light experiments often have to be performed without blackout. Put this idea into practice and each pupil can have a dark room--and best of all, it's free. In this article, the author describes…

Preliminary study on weapon grade uranium utilization in molten salt reactor miniFUJI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aji, Indarta Kuncoro; Waris, A., E-mail: awaris@fi.itb.ac.id

Preliminary study on weapon grade uranium utilization in 25MWth and 50MWth of miniFUJI MSR (molten salt reactor) has been carried out. In this study, a very high enriched uranium that we called weapon grade uranium has been employed in UF{sub 4} composition. The {sup 235}U enrichment is 90 - 95 %. The results show that the 25MWth miniFUJI MSR can get its criticality condition for 1.56 %, 1.76%, and 1.96% of UF{sub 4} with {sup 235}U enrichment of at least 93%, 90%, and 90%, respectively. In contrast, the 50 MWth miniFUJI reactor can be critical for 1.96% of UF{sub 4}more » with {sup 235}U enrichment of at smallest amount 95%. The neutron spectra are almost similar for each power output.« less

Mini-intervention for subacute low back pain: two-year follow-up and modifiers of effectiveness.

PubMed

Karjalainen, Kaija; Malmivaara, Antti; Mutanen, Pertti; Roine, Risto; Hurri, Heikki; Pohjolainen, Timo

2004-05-15

Randomized controlled trial. To Investigate the long-term effectiveness, costs, and effect modifiers of a mini-intervention, provided in addition to the usual care, and the incremental effect of a worksite visit for patients with subacute disabling low back pain (LBP). A mini-intervention was earlier proved to be an effective treatment for subacute LBP. Whether the beneficial effect is sustained is not known. Furthermore, modifiers of a treatment effect are largely unknown. A total of 164 patients with subacute LBP randomized into a mini-intervention (A, n = 56), a mini-intervention plus a worksite visit (B, n = 51), or the usual care (C, n = 57). Mini-intervention consisted of a detailed assessment of the patients' history, beliefs, and physical findings by a physician and a physiotherapist, followed by recommendations and advice. The usual care patients received the conventional care. Pain, disability, health-related quality of life, satisfaction with care, days on sick leave, and health care consumption and costs were measured during a 24-month follow-up. Thirteen candidate modifiers were tested for each outcome. There were no differences between the three treatment arms regarding the intensity of pain, the perceived disability, or the health-related quality of life. However, mini-intervention decreased occurrence of daily (A vs., C, P = 0.01) and bothersome (A vs. C, P < 0.05) pain and increased treatment satisfaction. Costs resulting from LBP were lower in the intervention groups (A 4670 Euros, B 5990 Euros) than in C (C 9510 Euros) (A vs. C, P = 0.04; and B vs. C, not significant). The average number of days on sick leave was 30 in A, 45 in B, and 62 in C (A vs. C, P = 0.03; B vs. C, not significant). The perceived risk for not recovering was the strongest modifier of treatment effect. Mental and mental-physical workers in A and B were less often on sick leave than those in C. Mini-intervention is an effective treatment for subacute LBP. Despite lack of a

A comparison of lead lengths for mini-fyke nets to sample age-0 gar species

USGS Publications Warehouse

Long, James M.; Snow, Richard A.; Patterson, Chas P.

2016-01-01

Mini-fyke nets are often used to sample small-bodied fishes in shallow (<1 m depth) water, especially in vegetated shoreline habitats where seines are ineffective. Recent interest in gar (Lepisosteidae) ecology and conservation led us to explore the use of mini-fyke nets to capture age-0 gar and specifically how capture is affected by lead length of the fyke net. In the summers of 2012, 2013, and 2015, mini-fyke nets with two different lead lengths (4.57 m and 9.14 m) were set at random sites in backwaters and coves of the Red River arm of Lake Texoma, Oklahoma. Mean CPUE (catch-per-unit-effort; number per net night) was significantly lower for mini-fyke nets with short leads (0.52) compared to those with long leads (1.51). Additionally, Spotted Gar (Lepisosteus oculatus) were captured at a higher rate than the other three gar species present in Lake Texoma, although this could have been an artifact of sampling location. We found that differences in length-frequency of captured gar between gear types were nearly significant, with total length ranging from 47mm to 590mm. Mini-fyke nets with longer leads increased the efficiency of sampling for age-0 gar by increasing catch rate without affecting estimates of other population parameters and appear to be useful for this purpose. 

Neutrino flux prediction at MiniBooNE

NASA Astrophysics Data System (ADS)

Aguilar-Arevalo, A. A.; Anderson, C. E.; Bazarko, A. O.; Brice, S. J.; Brown, B. C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J. M.; Cox, D. C.; Curioni, A.; Djurcic, Z.; Finley, D. A.; Fleming, B. T.; Ford, R.; Garcia, F. G.; Garvey, G. T.; Green, C.; Green, J. A.; Hart, T. L.; Hawker, E.; Imlay, R.; Johnson, R. A.; Karagiorgi, G.; Kasper, P.; Katori, T.; Kobilarcik, T.; Kourbanis, I.; Koutsoliotas, S.; Laird, E. M.; Linden, S. K.; Link, J. M.; Liu, Y.; Liu, Y.; Louis, W. C.; Mahn, K. B. M.; Marsh, W.; Martin, P. S.; McGregor, G.; Metcalf, W.; Meyers, P. D.; Mills, F.; Mills, G. B.; Monroe, J.; Moore, C. D.; Nelson, R. H.; Nguyen, V. T.; Nienaber, P.; Nowak, J. A.; Ouedraogo, S.; Patterson, R. B.; Perevalov, D.; Polly, C. C.; Prebys, E.; Raaf, J. L.; Ray, H.; Roe, B. P.; Russell, A. D.; Sandberg, V.; Schirato, R.; Schmitz, D.; Shaevitz, M. H.; Shoemaker, F. C.; Smith, D.; Soderberg, M.; Sorel, M.; Spentzouris, P.; Stancu, I.; Stefanski, R. J.; Sung, M.; Tanaka, H. A.; Tayloe, R.; Tzanov, M.; van de Water, R.; Wascko, M. O.; White, D. H.; Wilking, M. J.; Yang, H. J.; Zeller, G. P.; Zimmerman, E. D.

2009-04-01

The booster neutrino experiment (MiniBooNE) searches for νμ→νe oscillations using the O(1GeV) neutrino beam produced by the booster synchrotron at the Fermi National Accelerator Laboratory). The booster delivers protons with 8 GeV kinetic energy (8.89GeV/c momentum) to a beryllium target, producing neutrinos from the decay of secondary particles in the beam line. We describe the Monte Carlo simulation methods used to estimate the flux of neutrinos from the beam line incident on the MiniBooNE detector for both polarities of the focusing horn. The simulation uses the Geant4 framework for propagating particles, accounting for electromagnetic processes and hadronic interactions in the beam line materials, as well as the decay of particles. The absolute double differential cross sections of pion and kaon production in the simulation have been tuned to match external measurements, as have the hadronic cross sections for nucleons and pions. The statistical precision of the flux predictions is enhanced through reweighting and resampling techniques. Systematic errors in the flux estimation have been determined by varying parameters within their uncertainties, accounting for correlations where appropriate.

Hidden Item Variance in Multiple Mini-Interview Scores

ERIC Educational Resources Information Center

Zaidi, Nikki L.; Swoboda, Christopher M.; Kelcey, Benjamin M.; Manuel, R. Stephen

2017-01-01

The extant literature has largely ignored a potentially significant source of variance in multiple mini-interview (MMI) scores by "hiding" the variance attributable to the sample of attributes used on an evaluation form. This potential source of hidden variance can be defined as rating items, which typically comprise an MMI evaluation…

Bunko: Private Mini-Libraries for Children in Japan.

ERIC Educational Resources Information Center

Takeuchi, Satoru

"Bunko" are local mini-libraries for children in Japan, operated voluntarily by individuals or groups of parents, intended to nurture children's reading interest by offering them an inviting reading environment. In 1993, there were an estimated 4,000 bunko in Japan, with approximately 32,000 adult bunko members (90% female). Bunko…

[Our experience with mini tapes (TVT Secur and MiniArc) in the surgery for stress urinary incontinence].

PubMed

Jiménez Calvo, J; Hualde Alfaro, A; Raigoso Ortega, O; Cebrian Lostal, J L; Alvarez Bandres, S; Jiménez Parra, J; Montesino Semper, M; Santiago Gonzalez de Garibay, A

2008-01-01

The purpose of this publication is to describe the surgical technique, assess complications and short-term results of TVT secur and MiniArc tapes. From October 2006 to August 2007 it was carried out the surgical correction with TVT Secur,Women's Health & Urology, Ethicon, Johnson & Johnson, placing the tape as a hammock, to 51 patients, 38 of them with pure stress incontinence and 13 with mixed incontinence and with an average age of 57 years. From September 2007 to February 2008 41 patients, 33 of them with pure stress incontinence and 8 with mixed incontinence, with an average of age of 58 years were operated with AMS Miniarc swing system tape, posted on hammock. All procedures were performed with sedoanalgesia and Ambulatory Surgery regime. Patients were monitored in outpatient visits one month, 3 months and one year after surgical procedure. Medical history and questionnaire and ICIQ-SF, to which we added a question to quantify the degree of satisfaction, as well as physical examination, were done. We compared the results of both technical procedures and statistical survey was conducted by Student test. [Analysis with SPSS software (V14.0)]. The median follow-up in TVT secur group was 328 days (range 163-522 days) and 101 days (range 41-209 days) inthe MiniArc group. We only had one (TVT secur group) surgical complication in all the series (92 patients) being a bladder perforation. Taking into account that we read a negative test effort as an objective cure in the TVT secur group, 80.4% patients are cured and 90.2% inthe MiniArc group without significant difference between both groups (p 0095). To assess the subjective healing we utilized the ICIQ-SF test and the satisfaction extra-question and we noted that there is no significant difference between the first and third month controls. (90% of patients satisfied). 80% of patients were completely satisfied in the first year control that was only performed to TVT secur group. These new tapes show fewer

Real-time 3-D X-ray and gamma-ray viewer

NASA Technical Reports Server (NTRS)

Yin, L. I. (Inventor)

1983-01-01

A multi-pinhole aperture lead screen forms an equal plurality of invisible mini-images having dissimilar perspectives of an X-ray and gamma-ray emitting object (ABC) onto a near-earth phosphor layer. This layer provides visible light mini-images directly into a visible light image intensifier. A viewing screen having an equal number of dissimilar perspective apertures distributed across its face in a geometric pattern identical to the lead screen, provides a viewer with a real, pseudoscopic image (A'B'C') of the object with full horizontal and vertical parallax. Alternatively, a third screen identical to viewing screen and spaced apart from a second visible light image intensifier, may be positioned between the first image intensifier and the viewing screen, thereby providing the viewer with a virtual, orthoscopic image (A"B"C") of the object (ABC) with full horizontal and vertical parallax.

Gas Sensors Based on Tin Oxide Nanoparticles Synthesized from a Mini-Arc Plasma Source

DOE PAGES

Lu, Ganhua; Huebner, Kyle L.; Ocola, Leonidas E.; ...

2006-01-01

Minimore » aturized gas sensors or electronic noses to rapidly detect and differentiate trace amount of chemical agents are extremely attractive. In this paper, we report on the fabrication and characterization of a functional tin oxide nanoparticle gas sensor. Tin oxide nanoparticles are first synthesized using a convenient and low-cost mini-arc plasma source. The nanoparticle size distribution is measured online using a scanning electrical mobility spectrometer (SEMS). The product nanoparticles are analyzed ex-situ by high resolution transmission electron microscopy (HRTEM) for morphology and defects, energy dispersive X-ray (EDX) spectroscopy for elemental composition, electron diffraction for crystal structure, and X-ray photoelectron spectroscopy (XPS) for surface composition. Nonagglomerated rutile tin oxide ( SnO 2 ) nanoparticles as small as a few nm have been produced. Larger particles bear a core-shell structure with a metallic core and an oxide shell. The nanoparticles are then assembled onto an e-beam lithographically patterned interdigitated electrode using electrostatic force to fabricate the gas sensor. The nanoparticle sensor exhibits a fast response and a good sensitivity when exposed to 100 ppm ethanol vapor in air.« less

Relativistic Dynamics and Mass Exchange in Binary Black Hole Mini-disks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bowen, Dennis B.; Campanelli, Manuela; Mewes, Vassilios

We present the first exploration of gas dynamics in a relativistic binary black hole (BH) system in which an accretion disk (a “mini-disk”) orbits each BH. We focus on 2D hydrodynamical studies of comparable-mass, non-spinning systems. Relativistic effects alter the dynamics of gas in this environment in several ways. Because the gravitational potential between the two BHs becomes shallower than in the Newtonian regime, the mini-disks stretch toward the L1 point and the amount of gas passing back and forth between the mini disks increases sharply with decreasing binary separation. This “sloshing” is quasi-periodically modulated at 2 and 2.75 timesmore » the binary orbital frequency, corresponding to timescales of hours to days for supermassive binary black holes (SMBBHs). In addition, relativistic effects add an m = 1 component to the tidally driven spiral waves in the disks that are purely m = 2 in Newtonian gravity; this component becomes dominant when the separation is ≲100 gravitational radii. Both the sloshing and the spiral waves have the potential to create distinctive radiation features that may uniquely mark SMBBHs in the relativistic regime.« less

Relativistic Dynamics and Mass Exchange in Binary Black Hole Mini-disks

NASA Astrophysics Data System (ADS)

Bowen, Dennis B.; Campanelli, Manuela; Krolik, Julian H.; Mewes, Vassilios; Noble, Scott C.

2017-03-01

We present the first exploration of gas dynamics in a relativistic binary black hole (BH) system in which an accretion disk (a “mini-disk”) orbits each BH. We focus on 2D hydrodynamical studies of comparable-mass, non-spinning systems. Relativistic effects alter the dynamics of gas in this environment in several ways. Because the gravitational potential between the two BHs becomes shallower than in the Newtonian regime, the mini-disks stretch toward the L1 point and the amount of gas passing back and forth between the mini disks increases sharply with decreasing binary separation. This “sloshing” is quasi-periodically modulated at 2 and 2.75 times the binary orbital frequency, corresponding to timescales of hours to days for supermassive binary black holes (SMBBHs). In addition, relativistic effects add an m = 1 component to the tidally driven spiral waves in the disks that are purely m = 2 in Newtonian gravity; this component becomes dominant when the separation is ≲100 gravitational radii. Both the sloshing and the spiral waves have the potential to create distinctive radiation features that may uniquely mark SMBBHs in the relativistic regime.

Altered fibre types in gastrocnemius muscle of high wheel-running selected mice with mini-muscle phenotypes.

PubMed

Guderley, Helga; Joanisse, Denis R; Mokas, Sophie; Bilodeau, Geneviève M; Garland, Theodore

2008-03-01

Selective breeding of mice for high voluntary wheel running has favoured characteristics that facilitate sustained, aerobically supported activity, including a "mini-muscle" phenotype with markedly reduced hind limb muscle mass, increased mass-specific activities of oxidative enzymes, decreased % myosin heavy chain IIb, and, in the medial gastrocnemius, reduced twitch speed, reduced mass-specific isotonic power, and increased fatigue resistance. To evaluate whether selection has altered fibre type expression in mice with either "mini" or normal muscle phenotypes, we examined fibre types of red and white gastrocnemius. In both the medial and lateral gastrocnemius, the mini-phenotype increased activities of oxidative enzymes and decreased activities of glycolytic enzymes. In red muscle samples, the mini-phenotype markedly changed fibre types, with the % type I and type IIA fibres and the surface area of type IIA fibres increasing; in addition, mice from selected lines in general had an increased % type IIA fibres and larger type I fibres as compared with mice from control lines. White muscle samples from mini-mice showed dramatic structural alterations, with an atypical distribution of extremely small, unidentifiable fibres surrounded by larger, more oxidative fibres than normally present in white muscle. The increased proportion of oxidative fibres and these atypical small fibres together may explain the reduced mass and increased mitochondrial enzyme activities in mini-muscles. These and previous results demonstrate that extension of selective breeding beyond the time when the response of the selected trait (i.e. distance run) has levelled off can still modify the mechanistic underpinnings of this behaviour.

Factors Influencing Mini-CEX Rater Judgments and Their Practical Implications: A Systematic Literature Review.

PubMed

Lee, Victor; Brain, Keira; Martin, Jenepher

2017-06-01

At present, little is known about how mini-clinical evaluation exercise (mini-CEX) raters translate their observations into judgments and ratings. The authors of this systematic literature review aim both to identify the factors influencing mini-CEX rater judgments in the medical education setting and to translate these findings into practical implications for clinician assessors. The authors searched for internal and external factors influencing mini-CEX rater judgments in the medical education setting from 1980 to 2015 using the Ovid MEDLINE, PsycINFO, ERIC, PubMed, and Scopus databases. They extracted the following information from each study: country of origin, educational level, study design and setting, type of observation, occurrence of rater training, provision of feedback to the trainee, research question, and identified factors influencing rater judgments. The authors also conducted a quality assessment for each study. Seventeen articles met the inclusion criteria. The authors identified both internal and external factors that influence mini-CEX rater judgments. They subcategorized the internal factors into intrinsic rater factors, judgment-making factors (conceptualization, interpretation, attention, and impressions), and scoring factors (scoring integration and domain differentiation). The current theories of rater-based judgment have not helped clinicians resolve the issues of rater idiosyncrasy, bias, gestalt, and conflicting contextual factors; therefore, the authors believe the most important solution is to increase the justification of rater judgments through the use of specific narrative and contextual comments, which are more informative for trainees. Finally, more real-world research is required to bridge the gap between the theory and practice of rater cognition.

Assessment of postgraduate dental students using mini-clinical examination tool in periodontology and implantology

PubMed Central

Rathod, Surekha Ramrao; Kolte, Abhay; Shori, Tony; Kher, Vishal

2017-01-01

Introduction: Mini-clinical examination (mini-CEX) is a new assessment tool that observes the student using a standard rating form. The aim of this study was to evaluate the feasibility and usefulness of the mini-CEX as an assessment and feedback tool in the postgraduate setting in periodontology. Materials and Methods: Eight postgraduate students and two evaluators were included in this study carried out for 4 months during which the students were made to appear for four encounters evaluated on a standardized nine-point Likert scale. Feedback was obtained from the students about this assessment after the fourth encounter. Results: Sixty-three percent of the students felt that mini-CEX is better than the conventional assessment tools. Seventy-five percent of the students felt that this type of mini-CEX assessment helped improve the student–teacher relationship and student–patient relationship. Sixty-three percent of the students were satisfied with this assessment pattern and were willing to face more encounters as it helped them improve their competencies. Seventy-five percent of the students agreed that they felt anxious on being observed while taking cases. Conclusion: The training and assessment of a wide range of procedures make dentistry unique. Good communication skills and counseling can allay patient's fear and anxiety. This structured way of assessment of clinical skills and feedback provides good clinical care and helps improve the quality of the resulting information which would induce confidence, improve clinical competencies, and alleviate the fear of examination among the students. PMID:29491581

Matrix-mini-tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis

PubMed Central

Mohd, Abdul Hadi; Raghavendra Rao, Nidagurthi Guggilla; Avanapu, Srinivasa Rao

2014-01-01

Objective(s): The aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. Materials and Methods: Matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and pH-sensitive polymers which were further filled into an empty HPMC capsule. To assess the compatibility, FT-IR and DSC studies for pure drug, polymers and their physical mixture were performed. The formulated batches were subjected to physicochemical studies, estimation of drug content, in vitro drug release, drug release kinetics, and stability studies. Results: When FTIR and DSC studies were performed it was found that there was no interaction between lornoxicam and polymers which used. All the physicochemical properties of prepared matrix-mini-tablets were found to be in normal limits. The percentage of drug content was found to be 99.60±0.07%. Our optimized matrix mini-tablets-filled-capsule formulation F30 released lornoxicam after a lag time of 5.02±0.92 hr, 95.48±0.65 % at the end of 8 hr and 99.90±0.83 % at the end of 12 hr. Stability was also found for this formulation as per the guidelines of International Conference on Harmonisation of Technical Requirements of Pharmaceuticals for Human Use. Conclusion: A novel colon targeted delivery system of lornoxicam was successfully developed by filling matrix-mini-tablets into an empty HPMC capsule shell for targeting early morning peak symptoms of rheumatoid arthritis. PMID:24967065

Immediate costs of mini-open versus arthroscopic rotator cuff repair in an Asian population.

PubMed

Hui, Yik Jing; Teo, Alex Quok An; Sharma, Siddharth; Tan, Bryan Hsi Ming; Kumar, V Prem

2017-01-01

While there has been increasing interest in minimally invasive surgery, the expenses incurred by patients undergoing this form of surgery have not been comprehensively studied. The authors compared the costs borne by patients undergoing arthroscopic rotator cuff repair with the standard mini-open repair at a tertiary hospital in an Asian population. This was a retrospective cohort study. The authors studied the inpatient hospital bills of patients following rotator cuff tear repair between January 2010 and October 2014 via the hospital electronic medical records system. 148 patients had arthroscopic repair and 78 had mini-open repair. The cost of implants, consumables, and the total cost of hospitalization were analyzed. Operative times and length of stay for both procedures were also studied. Constant scores and American Shoulder Elbow Scores (ASES) were recorded preoperatively and at 1 year postoperatively. Three fellowship-trained surgeons performed arthroscopic repairs and one performed the mini-open repair. The cost of implants and consumables was significantly higher with arthroscopic repair. The duration of surgery was also significantly longer with that technique. There was no difference in length of stay between the two techniques. There was also no difference in Constant scores or ASES scores, both preoperatively and at 1 year postoperatively. The immediate costs of mini-open repair of rotator cuff tears are significantly less than that of arthroscopic repair. Most of the difference arises from the cost of implants and consumables. Equivalent functional outcomes from both techniques suggest that mini-open repair may be more cost-effective.

The Mini-Company, A New Approach to Office Education

ERIC Educational Resources Information Center

Smith, Genevieve

1973-01-01

A mini-company formed by the students and teachers of a three hour block of office education provides on the job experience as a method of improving office skills for twelfth graders at Fulton High School in Knoxville, Tennessee. (AG)

Civil mini-RPA's for the 1980's: Avionics design considerations. [remotely piloted vehicles

NASA Technical Reports Server (NTRS)

Karmarkar, J. S.

1975-01-01

A number of remote sensing or surveillance tasks (e.g., fire fighting, crop monitoring) in the civilian sector of our society may be performed in a cost effective manner by use of small remotely piloted aircraft (RPA). This study was conducted to determine equipment (and the associated technology) that is available, and that could be applied to the mini-RPA and to examine the potential applications of the mini-RPA with special emphasis on the wild fire surveillance mission. The operational considerations of using the mini-RPA as affected by government regulatory agencies were investigated. These led to equipment requirements (e.g., infra-red sensors) over and above those for the performance of the mission. A computer technology survey and forecast was performed. Key subsystems were identified, and a distributed microcomputer configuration, that was functionally modular, was recommended. Areas for further NASA research and development activity were also identified.

Mini-dome Fresnel lens photovoltaic concentrator development

NASA Technical Reports Server (NTRS)

Oneill, Mark J.; Piszczor, Michael F., Jr.

1991-01-01

Since 1986 work on a new high-performance, light-weight space photovoltaic concentration array has been conducted. An update on the mini-dome lens concentrator array development program is provided. Recent prototype cell and lens test results indicate that near-term array performance goals of 300 w/sq m and 100 w/kg are feasible, and that a longer-term goal of 200 w/kg is reasonable.

In silico and in vitro methods to optimize the performance of experimental gastroretentive floating mini-tablets.

PubMed

Eberle, Veronika A; Häring, Armella; Schoelkopf, Joachim; Gane, Patrick A C; Huwyler, Jörg; Puchkov, Maxim

2016-01-01

Development of floating drug delivery systems (FDDS) is challenging. To facilitate this task, an evaluation method was proposed, which allows for a combined investigation of drug release and flotation. It was the aim of the study to use functionalized calcium carbonate (FCC)-based lipophilic mini-tablet formulations as a model system to design FDDS with a floating behavior characterized by no floating lag time, prolonged flotation and loss of floating capability after complete drug release. Release of the model drug caffeine from the mini-tablets was assessed in vitro by a custom-built stomach model. A cellular automata-based model was used to simulate tablet dissolution. Based on the in silico data, floating forces were calculated and analyzed as a function of caffeine release. Two floating behaviors were identified for mini-tablets: linear decrease of the floating force and maintaining of the floating capability until complete caffeine release. An optimal mini-tablet formulation with desired drug release time and floating behavior was developed and tested. A classification system for a range of varied floating behavior of FDDS was proposed. The FCC-based mini-tablets had an ideal floating behavior: duration of flotation is defined and floating capability decreases after completion of drug release.

Critical factors for the success of orthodontic mini-implants: a systematic review.

PubMed

Chen, Yan; Kyung, Hee Moon; Zhao, Wen Ting; Yu, Won Jae

2009-03-01

This systematic review was undertaken to discuss factors that affect mini-implants as direct and indirect orthodontic anchorage. The data were collected from electronic databases (Medline [Entrez PubMed], Embase, Web of Science, Cochrane Library, and All Evidence Based Medicine Reviews). Randomized clinical trials, prospective and retrospective clinical studies, and clinical trials concerning the properties, affective factors, and requirements of mini-implants were considered. The titles and abstracts that appeared to fulfill the initial selection criteria were collected by consensus, and the original articles were retrieved and evaluated with a methodologic checklist. A hand search of key orthodontic journals was performed to identify recent unindexed literature. The search strategy resulted in 596 articles. By screening titles and abstracts, 126 articles were identified. After the exclusion criteria were applied, 16 articles remained. The analyzed results of the literature were divided into 2 topics: placement-related and loading-related factors. Mini-implants are effective as anchorage, and their success depends on proper initial mechanical stability and loading quality and quantity.

Enhancing Application Performance Using Mini-Apps: Comparison of Hybrid Parallel Programming Paradigms

NASA Technical Reports Server (NTRS)

Lawson, Gary; Sosonkina, Masha; Baurle, Robert; Hammond, Dana

2017-01-01

In many fields, real-world applications for High Performance Computing have already been developed. For these applications to stay up-to-date, new parallel strategies must be explored to yield the best performance; however, restructuring or modifying a real-world application may be daunting depending on the size of the code. In this case, a mini-app may be employed to quickly explore such options without modifying the entire code. In this work, several mini-apps have been created to enhance a real-world application performance, namely the VULCAN code for complex flow analysis developed at the NASA Langley Research Center. These mini-apps explore hybrid parallel programming paradigms with Message Passing Interface (MPI) for distributed memory access and either Shared MPI (SMPI) or OpenMP for shared memory accesses. Performance testing shows that MPI+SMPI yields the best execution performance, while requiring the largest number of code changes. A maximum speedup of 23 was measured for MPI+SMPI, but only 11 was measured for MPI+OpenMP.

Laser-Driven Mini-Thrusters

NASA Astrophysics Data System (ADS)

Sterling, Enrique; Lin, Jun; Sinko, John; Kodgis, Lisa; Porter, Simon; Pakhomov, Andrew V.; Larson, C. William; Mead, Franklin B.

2006-05-01

Laser-driven mini-thrusters were studied using Delrin® and PVC (Delrin® is a registered trademark of DuPont) as propellants. TEA CO2 laser (λ = 10.6 μm) was used as a driving laser. Coupling coefficients were deduced from two independent techniques: force-time curves measured with a piezoelectric sensor and ballistic pendulum. Time-resolved ICCD images of the expanding plasma and combustion products were analyzed in order to determine the main process that generates the thrust. The measurements were also performed in a nitrogen atmosphere in order to test the combustion effects on thrust. A pinhole transmission experiment was performed for the study of the cut-off time when the ablation/air breakdown plasma becomes opaque to the incoming laser pulse.

Mini-excimer laser corneal reshaping using a scanning device

NASA Astrophysics Data System (ADS)

Lin, Jui T.

1994-07-01

In this paper we present an update on the Mini-Excimer photorefractive keratectomy (PRK) laser system with an emphasis on the scanning device. We also compare the systems of various manufacturers. This paper also presents PMMA ablation profiles and clinical results from China with over 100 cases of myopic corrections ranging from -2.5 D to -12 D. In contrast to the old technology which uses industrial-type high-power excimer lasers, the advanced Mini-Excimer system uses the most recent technology involving a compact, high repetition-rate excimer laser operated at a much smaller beam spot size of (0.8 - 1.2) mm in a scanning mode which requires a beam energy per pulse of only (0.9 - 1.2) mJ on the corneal surface to achieve the same range of fluence (or energy density) (160 - 200) mJ/cm2 as that of the high-power excimer lasers.

MiniSipper: a new in situ water sampler for high-resolution, long-duration acid mine drainage monitoring.

PubMed

Chapin, Thomas P; Todd, Andrew S

2012-11-15

Abandoned hard-rock mines can be a significant source of acid mine drainage (AMD) and toxic metal pollution to watersheds. In Colorado, USA, abandoned mines are often located in remote, high elevation areas that are snowbound for 7-8 months of the year. The difficulty in accessing these remote sites, especially during winter, creates challenging water sampling problems and major hydrologic and toxic metal loading events are often under sampled. Currently available automated water samplers are not well suited for sampling remote snowbound areas so the U.S. Geological Survey (USGS) has developed a new water sampler, the MiniSipper, to provide long-duration, high-resolution water sampling in remote areas. The MiniSipper is a small, portable sampler that uses gas bubbles to separate up to 250 five milliliter acidified samples in a long tubing coil. The MiniSipper operates for over 8 months unattended in water under snow/ice, reduces field work costs, and greatly increases sampling resolution, especially during inaccessible times. MiniSippers were deployed in support of an U.S. Environmental Protection Agency (EPA) project evaluating acid mine drainage inputs from the Pennsylvania Mine to the Snake River watershed in Summit County, CO, USA. MiniSipper metal results agree within 10% of EPA-USGS hand collected grab sample results. Our high-resolution results reveal very strong correlations (R(2)>0.9) between potentially toxic metals (Cd, Cu, and Zn) and specific conductivity at the Pennsylvania Mine site. The large number of samples collected by the MiniSipper over the entire water year provides a detailed look at the effects of major hydrologic events such as snowmelt runoff and rainstorms on metal loading from the Pennsylvania Mine. MiniSipper results will help guide EPA sampling strategy and remediation efforts in the Snake River watershed. Published by Elsevier B.V.

MiniSipper: A new in situ water sampler for high-resolution, long-duration acid mine drainage monitoring

USGS Publications Warehouse

Chapin, Thomas P.; Todd, Andrew S.

2012-01-01

Abandoned hard-rock mines can be a significant source of acid mine drainage (AMD) and toxic metal pollution to watersheds. In Colorado, USA, abandoned mines are often located in remote, high elevation areas that are snowbound for 7–8 months of the year. The difficulty in accessing these remote sites, especially during winter, creates challenging water sampling problems and major hydrologic and toxic metal loading events are often under sampled. Currently available automated water samplers are not well suited for sampling remote snowbound areas so the U.S. Geological Survey (USGS) has developed a new water sampler, the MiniSipper, to provide long-duration, high-resolution water sampling in remote areas. The MiniSipper is a small, portable sampler that uses gas bubbles to separate up to 250 five milliliter acidified samples in a long tubing coil. The MiniSipper operates for over 8 months unattended in water under snow/ice, reduces field work costs, and greatly increases sampling resolution, especially during inaccessible times. MiniSippers were deployed in support of an U.S. Environmental Protection Agency (EPA) project evaluating acid mine drainage inputs from the Pennsylvania Mine to the Snake River watershed in Summit County, CO, USA. MiniSipper metal results agree within 10% of EPA-USGS hand collected grab sample results. Our high-resolution results reveal very strong correlations (R2 > 0.9) between potentially toxic metals (Cd, Cu, and Zn) and specific conductivity at the Pennsylvania Mine site. The large number of samples collected by the MiniSipper over the entire water year provides a detailed look at the effects of major hydrologic events such as snowmelt runoff and rainstorms on metal loading from the Pennsylvania Mine. MiniSipper results will help guide EPA sampling strategy and remediation efforts in the Snake River watershed.

Mini-Ckpts: Surviving OS Failures in Persistent Memory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fiala, David; Mueller, Frank; Ferreira, Kurt Brian

Concern is growing in the high-performance computing (HPC) community on the reliability of future extreme-scale systems. Current efforts have focused on application fault-tolerance rather than the operating system (OS), despite the fact that recent studies have suggested that failures in OS memory are more likely. The OS is critical to a system's correct and efficient operation of the node and processes it governs -- and in HPC also for any other nodes a parallelized application runs on and communicates with: Any single node failure generally forces all processes of this application to terminate due to tight communication in HPC. Therefore,more » the OS itself must be capable of tolerating failures. In this work, we introduce mini-ckpts, a framework which enables application survival despite the occurrence of a fatal OS failure or crash. Mini-ckpts achieves this tolerance by ensuring that the critical data describing a process is preserved in persistent memory prior to the failure. Following the failure, the OS is rejuvenated via a warm reboot and the application continues execution effectively making the failure and restart transparent. The mini-ckpts rejuvenation and recovery process is measured to take between three to six seconds and has a failure-free overhead of between 3-5% for a number of key HPC workloads. In contrast to current fault-tolerance methods, this work ensures that the operating and runtime system can continue in the presence of faults. This is a much finer-grained and dynamic method of fault-tolerance than the current, coarse-grained, application-centric methods. Handling faults at this level has the potential to greatly reduce overheads and enables mitigation of additional fault scenarios.« less

Expected rates with mini-arrays for air showers

NASA Technical Reports Server (NTRS)

Hazen, W. E.

1985-01-01

As a guide in the design of mini-arrays used to exploit the Linsley effect in the study of air showers, it is useful to calculate the expected rates. The results can aid in the choice of detectors and their placement or in predicting the utility of existing detector systems. Furthermore, the potential of the method can be appraised for the study of large showers. Specifically, we treat the case of a mini-array of dimensions small enough compared to the distance of axes of showers of interest so that it can be considered a point detector. The input information is taken from the many previous studies of air showers by other groups. The calculations will give: (1) the expected integral rate, F(sigma, rho), for disk thickness, sigma, or rise time, t sub 1/2, with local particle density, rho, as a parameter; (2) the effective detection area A(N) with sigma (min) and rho (min) and rho (min) as parameters; (3) the expected rate of collection of data F sub L (N) versus shower size, N.

Mineralogy at Meridiani Planum from the Mini-TES experiment on the opportunity rover

USGS Publications Warehouse

Christensen, P.R.; Wyatt, M.B.; Glotch, T.D.; Rogers, A.D.; Anwar, S.; Arvidson, R. E.; Bandfield, J.L.; Blaney, D.L.; Budney, C.; Calvin, W.M.; Fallacaro, A.; Fergason, R.L.; Gorelick, N.; Graff, T.G.; Hamilton, V.E.; Hayes, A.G.; Johnson, J. R.; Knudson, A.T.; McSween, H.Y.; Mehall, G.L.; Mehall, L.K.; Moersch, J.E.; Morris, R.V.; Smith, M.D.; Squyres, S. W.; Ruff, S.W.; Wolff, M.J.

2004-01-01

The Miniature Thermal Emission Spectrometer (Mini-TES) on Opportunity investigated the mineral abundances and compositions of outcrops, rocks, and soils at Meridiani Planum. Coarse crystalline hematite and olivine-rich basaltic sands were observed as predicted from orbital TES spectroscopy. Outcrops of aqueous origin are composed of 15 to 35% by volume magnesium and calcium sulfates [a high-silica component modeled as a combination of glass, feldspar, and sheet silicates (???20 to 30%)], and hematite; only minor jarosite is identified in Mini-TES spectra. Mini-TES spectra show only a hematite signature in the millimeter-sized spherules. Basaltic materials have more plagioclase than pyroxene, contain olivine, and are similar in inferred mineral composition to basalt mapped from orbit. Bounce rock is dominated by clinopyroxene and is close in inferred mineral composition to the basaltic martian meteorites. Bright wind streak material matches global dust. Waterlain rocks covered by unaltered basaltic sands suggest a change from an aqueous environment to one dominated by physical weathering.

Mapping of radiation anomalies using UAV mini-airborne gamma-ray spectrometry.

PubMed

Šálek, Ondřej; Matolín, Milan; Gryc, Lubomír

2018-02-01

Localization of size-limited gamma-ray anomalies plays a fundamental role in uranium prospecting and environmental studies. Possibilities of a newly developed mini-airborne gamma-ray spectrometric equipment were tested on a uranium anomaly near the village of Třebsko, Czech Republic. The measurement equipment was based on a scintillation gamma-ray spectrometer specially developed for unmanned aerial vehicles (UAV) mounted on powerful hexacopter. The gamma-ray spectrometer has two 103 cm 3 BGO scintillation detectors of relatively high sensitivity. The tested anomaly, which is 80 m by 40 m in size, was investigated by ground gamma-ray spectrometric measurement in a detail rectangular measurement grid. Average uranium concentration is 25 mg/kg eU attaining 700 mg/kg eU locally. The mini-airborne measurement across the anomaly was carried out on three 100 m long parallel profiles at eight flight altitudes from 5 to 40 m above the ground. The resulting 1 s 1024 channel gamma-ray spectra, recorded in counts per second (cps), were processed to concentration units of K, U and Th, while total count (TC) was reported in cps. Increased gamma ray intensity of the anomaly was indicated by mini-airborne measurement at all profiles and altitudes, including the highest altitude of 40 m, at which the recorded intensity is close to the natural radiation background. The reported instrument is able to record data with comparable quality as standard airborne survey, due to relative sensitive detector, lower flight altitude and relatively low flight speed of 1 m/s. The presented experiment brings new experience with using unmanned semi-autonomous aerial vehicles and the latest mini-airborne radiometric instrument. The experiment has demonstrated the instrument's ability to localize size-limited uranium anomalies. Copyright © 2017 Elsevier Ltd. All rights reserved.

Mini-intervention for subacute low back pain: a randomized controlled trial.

PubMed

Karjalainen, Kaija; Malmivaara, Antti; Pohjolainen, Timo; Hurri, Heikki; Mutanen, Pertti; Rissanen, Pekka; Pahkajärvi, Helena; Levon, Heikki; Karpoff, Hanna; Roine, Risto

2003-03-15

Randomized controlled trial. To investigate the effectiveness and costs of a mini-intervention, provided in addition to the usual care, and the incremental effect of a work site visit for patients with subacute disabling low back pain. There is lack of data on cost-effectiveness of brief interventions for patients with prolonged low back pain. A total of 164 patients with subacute low back pain were randomized to a mini-intervention group (A), a work site visit group (B), or a usual care group (C). Groups A (n = 56) and B (n = 51) underwent one assessment by a physician plus a physiotherapist. Group B received a work site visit in addition. Group C served as controls (n = 57) and was treated in municipal primary health care. All patients received a leaflet on back pain. Pain, disability, specific and generic health-related quality of life, satisfaction with care, days on sick leave, and use and costs of health care consumption were measured at 3-, 6-, and 12-month follow-ups. During follow-up, fewer subjects had daily pain in Groups A and B than in Group C (Group A Group C, = 0.002; Group B Group C, = 0.030). In Group A, pain was less bothersome (Group A Group C, = 0.032) and interfered less with daily life (Group A Group C, = 0.040) than among controls. Average days on sick leave were 19 in Group A, 28 in Group B, and 41 in Group C (Group A Group C, = 0.019). Treatment satisfaction was better in the intervention groups than among the controls, and costs were lowest in the mini-intervention group. Mini-intervention reduced daily back pain symptoms and sickness absence, improved adaptation to pain and patient satisfaction among patients with subacute low back pain, without increasing health care costs. A work site visit did not increase effectiveness.

Computational Toxicology - A State of the Science Mini Review

EPA Science Inventory

This mini-review is based on presentations and discussions at the International Science Forum on Computational Toxicology that was sponsored by the Office of Research and Development of the US Environmental Protection Agency and held in Research Triangle Park, NC on May 21-23, 20...

Imaging technique for the complete edentulous patient treated conventionally or with mini implant overdenture

PubMed Central

Meleşcanu Imre, M; Preoteasa, E; Țâncu, AM; Preoteasa, CT

2013-01-01

Rationale. The imaging methods are more and more used in the clinical process of modern dentistry. Once the implant based treatment alternatives are nowadays seen as being the standard of care in edentulous patients, these techniques must be integrated in the complete denture treatment. Aim. The study presents some evaluation techniques for the edentulous patient treated by conventional dentures or mini dental implants (mini SKY Bredent) overdentures, using the profile teleradiography. These offer data useful for an optimal positioning of the artificial teeth and the mini dental implants, favoring to obtain an esthetic and functional treatment outcome. We proposed also a method to conceive a simple surgical guide that allows the prosthetically driven implants placement. Material and method. Clinical case reports were made, highlighting the importance of cephalometric evaluation on lateral teleradiographs in complete edentulous patients. A clinical case that gradually reports the surgical guide preparation (Bredent silicon radio opaque), in order to place the mini dental implants in the best prosthetic and anatomic conditions, was presented. Conclusions. The profile teleradiograph is a useful tool for the practitioner. It allows establishing the optimal site for implant placement, in a good relation with the overdenture. The conventional denture can be easily and relatively costless transformed in a surgical guide used during implant placement. PMID:23599828

A Modular and Configurable Instrument Electronics Architecture for "MiniSAR"- An Advanced Smallsat SAR Instrument

NASA Astrophysics Data System (ADS)

Gomez, Jaime; Pastena, Max; Bierens, Laurens

2013-08-01

MiniSAR is a Dutch program focused on the development of a commercial smallsat featuring a SAR instrument, led by SSBV as prime contractor. In this paper an Instrument Electronics (IEL) system concept to meet the MiniSAR demands is presented. This system has several specificities wrt similar initiatives in the European space industry, driven by our main requirement: keep it small.

Comparative Clinical Study of Conventional Dental Implants and Mini Dental Implants for Mandibular Overdentures: A Randomized Clinical Trial.

PubMed

Aunmeungtong, Weerapan; Kumchai, Thongnard; Strietzel, Frank P; Reichart, Peter A; Khongkhunthian, Pathawee

2017-04-01

Dental implant-retained overdentures have been chosen as the treatment of choice for complete mandibular removable dentures. Dental implants, such as mini dental implants, and components for retaining overdentures, are commercially available. However, comparative clinical studies comparing mini dental implants and conventional dental implants using different attachment for implant-retained overdentures have not been well documented. To compare the clinical outcomes of using two mini dental implants with Equator ® attachments, four mini dental implants with Equator attachments, or two conventional dental implants with ball attachments, by means of a randomized clinical trial. Sixty patients received implant-retained mandibular overdentures in the interforaminal region. The patients were divided into three groups. In Groups 1 and 2, two and four mini dental implants, respectively, were placed and immediately loaded by overdentures, using Equator ® attachments. In Group 3, conventional implants were placed. After osseointegration, the implants were loaded by overdentures, using ball attachments. The study distribution was randomized and double-blinded. Outcome measures included changes in radiological peri-implant bone level from surgery to 12 months postinsertion, prosthodontic complications and patient satisfaction. The cumulative survival rate in the three clinical groups after one year was 100%. There was no significant difference (p < 0.05) in clinical results regarding the number (two or four) of mini dental implants with Equator attachments. However, there was a significant difference in marginal bone loss and patient satisfaction between those receiving mini dental implants with Equator attachments and conventional dental implants with ball attachments. The marginal bone resorption in Group 3 was significantly higher than in Groups 1 and 2 (p < 0.05); there were no significant differences between Groups 1 and 2. There was no significant difference in

A Mini-Course for Social Studies. Subject: History of Flight

ERIC Educational Resources Information Center

Knight, Luise M.

1977-01-01

Lists seven objectives and supplies a course outline and sample pretest for a mini-course in the History of Aviation (Social Studies) for high school students. Supplemental books and audiovisual materials are listed. Bibliography included. (CS)

Functional Movements in Japanese Mini-Basketball Players

PubMed Central

Kuzuhara, Kenji; Shibata, Masashi; Iguchi, Junta; Uchida, Ryo

2018-01-01

Abstract Functional movement screen (FMS) has been used to establish normative data and determine potential injury risk for young adults and athletes, but there are few data in elementary school-age children. The purpose of this study was to establish fundamental values for the FMS in elementary school-age mini-basketball players. Secondary purposes were to examine relationships between functional movement patterns and age, peak height velocity (PHV), and body mass index (BMI), and to compare functional movement patterns between boys and girls and between individuals with and without a history of injury. The mean composite FMS score was 16.5 ± 2.2 (16.5 ± 2.4 for boys, 16.5 ± 1.7 for girls). The composite FMS score was positively correlated with age (r = .312) and negatively correlated with the BMI (r = − .371). However, the FMS score was not correlated with PHV or with PHV age. The FMS score was not different between boys and girls or between individuals who reported a previous injury and those who did not. However, boys in the mini-basketball teams performed better than girls on the trunk stability push-up and rotary stability tests. Age and the body mass index were significantly associated with better and poorer functional movement, respectively. PMID:29599859

Functional Movements in Japanese Mini-Basketball Players.

PubMed

Kuzuhara, Kenji; Shibata, Masashi; Iguchi, Junta; Uchida, Ryo

2018-03-01

Functional movement screen (FMS) has been used to establish normative data and determine potential injury risk for young adults and athletes, but there are few data in elementary school-age children. The purpose of this study was to establish fundamental values for the FMS in elementary school-age mini-basketball players. Secondary purposes were to examine relationships between functional movement patterns and age, peak height velocity (PHV), and body mass index (BMI), and to compare functional movement patterns between boys and girls and between individuals with and without a history of injury. The mean composite FMS score was 16.5 ± 2.2 (16.5 ± 2.4 for boys, 16.5 ± 1.7 for girls). The composite FMS score was positively correlated with age (r = .312) and negatively correlated with the BMI (r = - .371). However, the FMS score was not correlated with PHV or with PHV age. The FMS score was not different between boys and girls or between individuals who reported a previous injury and those who did not. However, boys in the mini-basketball teams performed better than girls on the trunk stability push-up and rotary stability tests. Age and the body mass index were significantly associated with better and poorer functional movement, respectively.

Embedding Hands-On Mini Laboratory Experiences in a Core Undergraduate Fluid Mechanics Course: A Pilot Study

ERIC Educational Resources Information Center

Han, Duanduan; Ugaz, Victor

2017-01-01

Three self-contained mini-labs were integrated into a core undergraduate fluid mechanics course, with the goal of delivering hands-on content in a manner scalable to large class sizes. These mini-labs supported learning objectives involving friction loss in pipes, flow measurement, and centrifugal pump analysis. The hands-on experiments were…

Comparison of intrusion effects on maxillary incisors among mini implant anchorage, j-hook headgear and utility arch.

PubMed

Jain, Ravindra Kumar; Kumar, Sridhar Prem; Manjula, W S

2014-07-01

Intrusion of maxillary incisors is one of the most important and difficult tooth movements to achieve as a part of orthodontic therapy. A variety of techniques were used in the past to intrude the maxillary incisors before the emergence of mini implants in Orthodontics. Mini implants are temporary anchorage devices used to produce various tooth movements. The research was carried out to evaluate and compare the efficiency of producing intrusion of maxillary incisors using mini implants, utility arch and j- hook headgear. The study was conducted on 30 subjects divided into 3 Groups equally. Group 1- mini implant anchorage, Group 2 - j- hooks headgear and Group 3- utility arch were used for intrusion of the maxillary incisors. Conventional lateral cephalograms were taken before treatment and at the end of intrusion. Five cephalometric parameters were used to measure the amount of intrusion attained in each Group. Intra Group comparisons were done using student t-test and inter Group comparisons were done using ANOVA The duration of intrusion was four months in all the three Groups. In Group 1 the mean average intrusion attained was 2.1 mm, the mean average intrusion attained in Group 2 was 0.7 mm, and the mean average intrusion achieved in Group 3 was 1.4 mm with a side effect of 0.75 mm of molar extrusion. Although, both mini implants and utility arch can be used to attain significant amounts of incisor intrusion but using mini implants will produce true intrusion without any other side effects.

Er:YAG laser, piezosurgery, and surgical drill for bone decortication during orthodontic mini-implant insertion: primary stability analysis-an animal study.

PubMed

Matys, Jacek; Flieger, Rafał; Tenore, Gianluca; Grzech-Leśniak, Kinga; Romeo, Umberto; Dominiak, Marzena

2018-04-01

It is important to identify factors that affect primary stability of orthodontic mini-implants because it determines the success of treatment. We assessed mini-implant primary stability (initial mechanical engagement with the bone) placed in pig jaws. We also assessed mini-implant insertion failure rate (mini-implant fracture, mini-implants to root contact). A total of 80 taper-shaped mini-implants (Absoanchor® Model SH1312-6; Dentos Inc., Daegu, Korea) 6 mm long with a diameter of 1.1 mm were used. Bone decortication was made before mini-implant insertion by means of three different methods: Group G1: Er:YAG laser (LiteTouch®, Light Instruments, Yokneam, Israel) at energy of 300 mJ, frequency 25 Hz, fluence 38.2 J/cm2, cooling 14 ml/min, tip 1.0 × 17 mm, distance 1 mm, time of irradiation 6 s; Group G2: drill (Hager & Meisinger GmbH, Hansemannstr, Germany); Group G3: piezosurgery (Piezotom Solo, Acteon, NJ, USA). In G4 group (control), mini-implants were driven by a self-drilling method. The primary stability of mini-implants was assessed by measuring damping characteristics between the implant and the tapping head of Periotest device (Gulden-Medizinteknik, Eschenweg, Modautal, Germany). The results in range between - 8 to + 9 allowed immediate loading. Significantly lower Periotest value was found in the control group (mean 0.59 ± 1.57, 95% CI 0.7, 2.4) as compared with Er:YAG laser (mean 4.44 ± 1.64, 95% CI 3.6, 5.3), piezosurgery (mean 17.92 ± 2.73, 95% CI 16.5, 19.3), and a drill (mean 5.91 ± 1.52, 95% CI 5.2, 6.6) (p < 0.05). The highest failure rate (33.3%) during mini-implant insertion was noted for self-drilling method (G4) as compared with G1, G2, and G3 groups (p < 0.05). The small diameter decortication by Er:YAG laser appeared to provide better primary stability as compared to drill and piezosurgery. Decortication of the cortical bone before mini-implant insertion resulted in reduced risk of implant fracture

Ability of mini-implant-facilitated micro-osteoperforations to accelerate tooth movement in rats.

PubMed

Cheung, Tracy; Park, Juyoung; Lee, Deborah; Kim, Catherine; Olson, Jeffrey; Javadi, Shadi; Lawson, Gregory; McCabe, James; Moon, Won; Ting, Kang; Hong, Christine

2016-12-01

Although current techniques for accelerated tooth movement often involve invasive surgical procedures, micro-osteoperforations (MOPs) using mini-implants may facilitate orthodontic tooth movement without raising flaps, reduce surgical risks, and increase patient acceptance. In this study, we evaluated the effectiveness of mini-implant-facilitated MOPs in inducing accelerated tooth movement and investigated the potential risks for root resorption. Five MOPs were placed on the left side around the maxillary first molars in 6 rats using an automated mini-implant driver, whereas the right side received no MOPs as the control. Closed-coiled springs were secured from incisors to first molars for orthodontic tooth movement. Tooth movement was measured, and samples underwent radiologic and histologic analyses. The MOP side exhibited a 1.86-fold increase in the rate of tooth movement with decreased bone density and bone volume around the first molars compared with the control side. Hematoxylin and eosin and tartrate-resistant acid phosphatase analyses showed increased numbers of osteoclasts as well as new bone formation. Three-dimensional volumetric analysis of all 5 roots of the maxillary first molars demonstrated no statistically significant difference in root volumes. Mini-implant-facilitated MOPs accelerated tooth movement without increased risk for root resorption and therefore may become a readily available and efficient treatment option to shorten orthodontic treatment time with improved patient acceptance. Copyright © 2016 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

Operative techniques of percutaneous endoscopic mini-hemilaminectomy using a uniportal approach in dogs

PubMed Central

MOON, Hee-Sup; HWANG, Yong-Hyun; LEE, Hee-Chun; LEE, Jae-Hoon

2017-01-01

The present study aimed to investigate the technical feasibility of percutaneous endoscopic mini-hemilaminectomy via a uniportal approach, and to evaluate the possibility of decompression and endoscopic examination of the thoracic and lumbar spinal canals in small dogs during such procedures. Fresh canine cadavers of mixed-breed dogs (n=7) were used in this study. Following injection of a barium and agarose mixture (BA-gel) to stimulate intervertebral disc herniation, percutaneous endoscopic mini-hemilaminectomy was performed using a lateral approach to the thoracic and lumbar vertebrae. BA-gel was removed to decompress the spinal cord using an elevator and rongeurs after mini-hemilaminectomy. Pre and post-operative computed tomography (CT) scans were obtained to evaluate surgical outcomes. Intra-operative complications, incision length, and procedure time were recorded. All procedures were completed with clear visualization of the spinal cord and floor of the spinal canal. The mean total operating time was 58.00 ± 18.06 min. Lengths of incision were under 1 cm in all dogs. Intra-operative complications included iatrogenic nerve root injuries caused by the micro-rongeur in two dogs. CT imaging revealed that removal of BA-gel resulted in sufficient spinal cord decompression. Our findings indicated that percutaneous endoscopic thoracolumbar mini-hemilaminectomy is feasible for spinal cord decompression and allows for adequate observation of the spinal canal. Thus, this technique may be an alternative surgical option for treatment of thoracolumbar disk disease in dogs. PMID:28757523

[Comparison of endotracheal aspiration and mini-BAL culture results in the diagnosis of ventilator-associated pneumonia].

PubMed

Artuk, Cumhur; Gül, Hanefi Cem; Mert, Gürkan; Karakaş, Ahmet; Bedir, Orhan; Eyigün, Can Polat

2012-07-01

The objective of this study was to compare the results of cultures obtained by mini-bronchoalveolar lavage (BAL) and endotracheal aspiration (ETA) techniques, used for rapid and accurate determination of pathogens causing ventilator-associated pneumonia (VAP) in intensive care units. Of the 92 patients on mechanical ventilation followed at the emergency intensive care unit of our hospital between June 2010 and June 2011, 30 (32.2%) patients were diagnosed as VAP and they were included in this study. VAP diagnosis were based on the clinical and radiological findings. Clinical pulmonary infection score (CPIS) of > 6 was accepted as the clinical criteria of VAP. Initially ETA samples were collected from the patients followed by mini-BAL sampling 15 minutes later, together with urine and two blood cultures. Microbiological evaluation and identification were performed by conventional methods and Phoenix 100 (BD Diagnostic Systems, ABD) automated system. In quantitative culture analysis, > 10.000 cfu/ml for BAL and > 100.000 cfu/ml for ETA were accepted as the positive result. The mean ages of VAP-developed (n= 30; 18 were male) and nondeveloped (n= 62; 39 were male) patients were 68.23 ± 16.19 and 52.16 ± 10.41 years, respectively, and the mean durations of mechanical ventilation were 29.57 ± 15.78 and 12.11 ± 6.01 days, respectively. Multivariate logistic regression analysis showed that older age (p< 0.001) and duration of mechanical ventilation (p< 0.001) were independent risk factors for VAP development. There was also a statistically significant difference in CPIS values between patients who developed VAP and not (6.8 ± 1.15 and 2.71 ± 1.06, respectively; p< 0.001). The use of CPIS for VAP diagnosis was found to be useful in patients on mechanical ventilation. In our study, a total of 16 strains (six A.baumannii, three P.aeruginosa, one K.pneumoniae, six S.aureus) were isolated from ETA cultures, while 34 strains (16 A.baumannii, six P.aeruginosa, four K

Mini-FLOTAC, an Innovative Direct Diagnostic Technique for Intestinal Parasitic Infections: Experience from the Field

PubMed Central

Barda, Beatrice Divina; Rinaldi, Laura; Ianniello, Davide; Zepherine, Henry; Salvo, Fulvio; Sadutshang, Tsetan; Cringoli, Giuseppe; Clementi, Massimo; Albonico, Marco

2013-01-01

Background Soil-transmitted helminths and intestinal protozoa infection are widespread in developing countries, yet an accurate diagnosis is rarely performed. The aim of this study was to evaluate the recently developed mini–FLOTAC method and to compare with currently more widely used techniques for the diagnosis of intestinal parasitic infections in different settings. Methodology/Principal Findings The study was carried out in Dharamsala, Himachal Pradesh, India, and in Bukumbi, Tanzania. A total of 180 pupils from two primary schools had their stool analyzed (n = 80 in Dharamsala and n = 100 in Bukumbi) for intestinal parasitic infections with three diagnostic methods: direct fecal smear, formol-ether concentration method (FECM) and mini-FLOTAC. Overall, 72% of the pupils were positive for any intestinal parasitic infection, 24% carried dual infections and 11% three infections or more. The most frequently encountered intestinal parasites were Entamoeba coli, Entamoeba histolytica/dispar, Giardia intestinalis, hookworm, (and Schistosoma mansoni, in Tanzania). Statistically significant differences were found in the detection of parasitic infections among the three methods: mini-FLOTAC was the most sensitive method for helminth infections (90% mini-FLOTAC, 60% FECM, and 30% direct fecal smear), whereas FECM was most sensitive for intestinal protozoa infections (88% FECM, 70% direct fecal smear, and 68% mini-FLOTAC). Conclusion/Significance We present the first experiences with the mini-FLOTAC for the diagnosis of intestinal helminths and protozoa. Our results suggest that it is a valid, sensitive and potentially low-cost alternative technique that could be used in resource-limited settings — particularly for helminth diagnosis. PMID:23936577

Microalgae-microbial fuel cell: A mini review.

PubMed

Lee, Duu-Jong; Chang, Jo-Shu; Lai, Juin-Yih

2015-12-01

Microalgae-microbial fuel cells (mMFCs) are a device that can convert solar energy to electrical energy via biological pathways. This mini-review lists new research and development works on microalgae processes, microbial fuel cell (MFC) processes, and their combined version, mMFC. The substantial improvement and technological advancement are highlighted, with a discussion on the challenges and prospects for possible commercialization of mMFC technologies. Copyright © 2015 Elsevier Ltd. All rights reserved.

Effect of rater training on reliability and accuracy of mini-CEX scores: a randomized, controlled trial.

PubMed

Cook, David A; Dupras, Denise M; Beckman, Thomas J; Thomas, Kris G; Pankratz, V Shane

2009-01-01

Mini-CEX scores assess resident competence. Rater training might improve mini-CEX score interrater reliability, but evidence is lacking. Evaluate a rater training workshop using interrater reliability and accuracy. Randomized trial (immediate versus delayed workshop) and single-group pre/post study (randomized groups combined). Academic medical center. Fifty-two internal medicine clinic preceptors (31 randomized and 21 additional workshop attendees). The workshop included rater error training, performance dimension training, behavioral observation training, and frame of reference training using lecture, video, and facilitated discussion. Delayed group received no intervention until after posttest. Mini-CEX ratings at baseline (just before workshop for workshop group), and four weeks later using videotaped resident-patient encounters; mini-CEX ratings of live resident-patient encounters one year preceding and one year following the workshop; rater confidence using mini-CEX. Among 31 randomized participants, interrater reliabilities in the delayed group (baseline intraclass correlation coefficient [ICC] 0.43, follow-up 0.53) and workshop group (baseline 0.40, follow-up 0.43) were not significantly different (p = 0.19). Mean ratings were similar at baseline (delayed 4.9 [95% confidence interval 4.6-5.2], workshop 4.8 [4.5-5.1]) and follow-up (delayed 5.4 [5.0-5.7], workshop 5.3 [5.0-5.6]; p = 0.88 for interaction). For the entire cohort, rater confidence (1 = not confident, 6 = very confident) improved from mean (SD) 3.8 (1.4) to 4.4 (1.0), p = 0.018. Interrater reliability for ratings of live encounters (entire cohort) was higher after the workshop (ICC 0.34) than before (ICC 0.18) but the standard error of measurement was similar for both periods. Rater training did not improve interrater reliability or accuracy of mini-CEX scores. clinicaltrials.gov identifier NCT00667940

How useful are the "other" semipermeable membrane devices (SPMDs); the mini-unit (15.2 cm long)?

USGS Publications Warehouse

Goodbred, Steven L.; Bryant, Wade L.; Rosen, Michael R.; Alvarez, David; Spencer, Terri

2009-01-01

Mini (15.2 cm) semipermeable membrane devices (SPMDs) were used successfully in 169 streams from six metropolitan areas of the US to sequester hydrophobic organic compounds (HOCs) that are indicative of urbanization. A microscale assay the P450RGS, which responds to compounds that bind to the aryl hydrocarbon receptor (AhR), and the Fluoroscan, a chemical screen for polycyclic aromatic hydrocarbons (PAHs), were performed on each mini SPMD extract. Results show both tests were sensitive enough to respond in streams with low urbanization and responded exponentially in a predictable way to a gradient of urbanization. Mini SPMDs had sufficient sampling rates to detect HOCs using gas chromatography with mass spectrometric detection (GC/MS) in streams with low levels of urbanization. The total number of HOCs in streams had a linear response to a gradient of urbanization, where 73 of 140 targeted compounds were detected. A diverse group of compounds was found in urban streams including, PAHs, insecticides, herbicides, musk fragrances, waste water treatment compounds and flame retardants. Pentachloroanisole (PCA), a breakdown product of pentachlorophenol (wood preservative), was the most ubiquitous HOC, and was detected in 71% of streams. An evaluation of mini SPMD performance showed they can detect concentrations in water below toxicity benchmarks for many HOCs with the exception of 2,3,7,8 tetrachlorodibenzo-p-dioxin. A comparison of mini SPMDs with full sized (91.4 cm) SPMDs showed they have several distinct advantages. The most notable advantages are their low cost, small size, and reduced chance of vandalism. The greatest limitation is the inability to detect compounds at low concentrations (pg/L). Mini SPMDs perform quite well in a wide array of environmental settings and applications and should be considered as an option in environmental studies.

A mini axial and a permanent maglev radial heart pump.

PubMed

Qian, Kun-Xi; Ru, Wei-Min; Wang, Hao; Jing, Teng

2007-05-31

The implantability and durability have been for decades the focus of artificial heart R&D. A mini axial and a maglev radial pump have been developed to meet with such requirements.The mini axial pump weighing 27g (incl.5g rotor) has an outer diameter of 21mm and a length of 10mm in its largest point, but can produce a maximal blood flow of 6l/min with 50mmHg pressure increase. Therefore, it is suitable for the patients of 40-60kg body weight. For other patients of 60-80kg or 80-100kg body weight, the mini axial pumps of 23mm and 25mm outer diameter had been developed before, these devices were acknowledged to be the world smallest LVADs by Guinness World Record Center in 2004.The permanent maglev radial pump weighing 150g is a shaft-less centrifugal pump with permanent magnetic bearings developed by the author. It needs no second coil for suspension of the rotor except the motor coil, different from all other maglev pumps developed in USA, Japan, European, etc. Thus no detecting and controlling systems as well as no additional power supply for maglev are necessary. The pump can produce a blood flow up to as large as 10l/min against 100mmHg pressure.An implantable and durable blood pump will be a viable alternative to natural donor heart for transplantation.

Achievable Inquiry in the College Laboratory: The Mini-Journal

ERIC Educational Resources Information Center

Witzig, Stephen B.; Zhao, Ningfeng; Abell, Sandra K.; Weaver, Jan C.; Adams, John E.; Schmidt, Frank J.

2010-01-01

The authors engage students in inquiry-based learning by presenting laboratory exercises as mini-journal articles that mirror the format of a scientific journal article, including a title, authors, abstract, introduction, materials and methods, results, discussion, and citations. Students develop and carry out their follow-up investigation, then…

Actividades al Aire Libre (Outdoor Activities). OBIS/Mini-Corps.

ERIC Educational Resources Information Center

California Univ., Berkeley. Lawrence Hall of Science.

The all-Spanish version of the Outdoor Biology Instructional Strategies (OBIS)/Mini-Corps Outdoor Activities set contains twenty education and recreational activities which provide a variety of outdoor biological experiences and incorporate language skills into outdoor education. Prepared especially for use by migrant children aged 10-15 in a…

Luminescence properties after X-ray irradiation for dosimetry

NASA Astrophysics Data System (ADS)

Hong, Duk-Geun; Kim, Myung-Jin

2016-05-01

To investigate the luminescence characteristics after exposure to X-ray radiation, we developed an independent, small X-ray irradiation system comprising a Varian VF-50J mini X-ray generator, a Pb collimator, a delay shutter, and an Al absorber. With this system, the apparent dose rate increased linearly to 0.8 Gy/s against the emission current for a 50 kV anode potential when the shutter was delayed for an initial 4 s and the Al absorber was 300 µm thick. In addition, an approximately 20 mm diameter sample area was irradiated homogeneously with X rays. Based on three-dimensional (3D) thermoluminescence (TL) spectra, the small X-ray irradiator was considered comparable to the conventional 90Sr/90Y beta source even though the TL intensity from beta irradiation was higher than that from X-ray irradiation. The single aliquot regenerative (SAR) growth curve for the small X-ray irradiator was identical to that for the beta source. Therefore, we concluded that the characteristics of the small X-ray irradiator and the conventional 90Sr/90Y beta source were similar and that X ray irradiation had the potential for being suitable for use in luminescence dosimetry.

Limited efficiency of universal mini-barcode primers for DNA amplification from desert reptiles, birds and mammals.

PubMed

Arif, I A; Khan, H A; Al Sadoon, M; Shobrak, M

2011-10-31

In recent years, DNA barcoding has emerged as a powerful tool for species identification. We report an extended validation of a universal DNA mini-barcode for amplification of 130-bp COI segments from 23 specimens collected from a desert environment, including 11 reptiles, five mammals and seven birds. Besides the standard double-annealing protocol, we also tested a more stringent single-annealing protocol. The PCR success rate for the amplification of the mini-barcode region was: mammals (4/5), reptiles (5/11) and birds (4/7). These findings demonstrate the limited utility of universal primers for mini-barcoding, at least for these vertebrate taxa that we collected from the Saudi Arabian desert.

Mini-Fragment Fixation Is Equivalent to Bicortical Screw Fixation for Horizontal Medial Malleolus Fractures.

PubMed

Wegner, Adam M; Wolinsky, Philip R; Robbins, Michael A; Garcia, Tanya C; Amanatullah, Derek F

2018-05-01

Horizontal fractures of the medial malleolus occur through application of valgus or abduction force through the ankle that creates a tension failure of the medial malleolus. The authors hypothesize that mini-fragment T-plates may offer improved fixation, but the optimal fixation construct for these fractures remains unclear. Forty synthetic distal tibiae with identical osteotomies were randomized into 4 fixation constructs: (1) two parallel unicortical cancellous screws; (2) two parallel bicortical cortical screws; (3) a contoured mini-fragment T-plate with 2 unicortical screws in the fragment and 2 bicortical screws in the shaft; and (4) a contoured mini-fragment T-plate with 2 bicortical screws in the fragment and 2 unicortical screws in the shaft. Specimens were subjected to offset axial tension loading on a servohydraulic testing system and tracked using high-resolution video. Failure was defined as 2 mm of articular displacement. Analysis of variance followed by a Tukey-Kramer post hoc test was used to assess for differences between groups, with significance defined as P<.05. The mean stiffness (±SD) values of both mini-fragment T-plate constructs (239±83 N/mm and 190±37 N/mm) and the bicortical screw construct (240±17 N/mm) were not statistically different. The mean stiffness values of both mini-fragment T-plate constructs and the bicortical screw construct were higher than that of a parallel unicortical screw construct (102±20 N/mm). Contoured T-plate constructs provide stiffer initial fixation than a unicortical cancellous screw construct. The T-plate is biomechanically equivalent to a bicortical screw construct, but may be superior in capturing small fragments of bone. [Orthopedics. 2018; 41(3):e395-e399.]. Copyright 2018, SLACK Incorporated.

JaSTA-2: Second version of the Java Superposition T-matrix Application

NASA Astrophysics Data System (ADS)

Halder, Prithish; Das, Himadri Sekhar

2017-12-01

In this article, we announce the development of a new version of the Java Superposition T-matrix App (JaSTA-2), to study the light scattering properties of porous aggregate particles. It has been developed using Netbeans 7.1.2, which is a java integrated development environment (IDE). The JaSTA uses double precision superposition T-matrix codes for multi-sphere clusters in random orientation, developed by Mackowski and Mischenko (1996). The new version consists of two options as part of the input parameters: (i) single wavelength and (ii) multiple wavelengths. The first option (which retains the applicability of older version of JaSTA) calculates the light scattering properties of aggregates of spheres for a single wavelength at a given instant of time whereas the second option can execute the code for a multiple numbers of wavelengths in a single run. JaSTA-2 provides convenient and quicker data analysis which can be used in diverse fields like Planetary Science, Atmospheric Physics, Nanoscience, etc. This version of the software is developed for Linux platform only, and it can be operated over all the cores of a processor using the multi-threading option.

In vitro comparison of endplate preparation between four mini-open interbody fusion approaches.

PubMed

Tatsumi, Robert; Lee, Yu-Po; Khajavi, Kaveh; Taylor, William; Chen, Foster; Bae, Hyun

2015-04-01

Discectomy and endplate preparation are important steps in interbody fusion for ensuring sufficient arthrodesis. While modern less-invasive approaches for lumbar interbody fusion have gained in popularity, concerns exist regarding their ability to allow for adequate disc space and endplate preparation. Thus, the purpose of this study was to quantitatively and qualitatively evaluate and compare disc space and endplate preparation achieved with four less-invasive approaches for lumbar interbody fusion in cadaveric spines. A total of 24 disc spaces (48 endplates) from L2 to L5 were prepared in eight cadaveric torsos using mini-open anterior lumbar interbody fusion (mini-ALIF), minimally invasive posterior lumbar interbody fusion (MAS PLIF), minimally invasive transforaminal lumbar interbody fusion (MAS TLIF) or minimally invasive lateral, transpsoas interbody fusion (XLIF) on two specimens each, for a total of six levels and 12 endplates prepared per procedure type. Following complete discectomy and endplate preparation, spines were excised and split axially at the interbody disc spaces. Endplates were digitally photographed and evaluated using image analysis software. Area of endplate preparation was measured and qualitative evaluation was also performed to grade the quality of preparation. The XLIF approach resulted in the greatest relative area of endplate preparation (58.3 %) while mini-ALIF resulted in the lowest at 35.0 %. Overall, there were no differences in percentage of preparation between cranial and caudal endplates, though this was significantly different in the XLIF group (65 vs 52 %, respectively). ALL damage was observed in 3 MAS TLIF levels. Percentage of endplate that was deemed to have complete disc removal was highest in XLIF group with 90 % compared to 65 % in MAS TLIF group, 43 % in MAS PLIF, and 40 % in mini-ALIF group. Endplate damage area was highest in the MAS TLIF group at 48 % and lowest in XLIF group at 4 %. These results demonstrate that

Biomechanics and load resistance of small-diameter and mini dental implants: a review of literature.

PubMed

Hasan, Istabrak; Bourauel, Christoph; Mundt, Torsten; Stark, Helmut; Heinemann, Friedhelm

2014-02-01

In recent years, the application of small-diameter and mini dental implants to support removable and fixed prosthesis has dramatically increased. However, the success of these implants under functional biting forces and the reaction of the bone around them need to be analyzed. This review was aimed to present studies that deal with the fatigue life of small-diameter and mini dental implants under normal biting force, and their survival rate. The numerical and experimental studies concluded that an increase in the risk of bone damage or implant failure may be assumed in critical clinical situations and implants with <3 mm diameter have a risk of fracture in clinical practice. The survival rate of the small-diameter and mini dental implants over 5 years was 98.3-99.4%.

High-Rate Mechanical Properties of JA2 Propellant at Temperatures from -50 to 80 deg C

DTIC Science & Technology

2015-07-01

panorama of postcompression JA2 grain sample (uniaxially compressed at a rate of ~100 s–1, 80 °C, and strain greater than 40%), 50× magnification...19 Fig. 36 SEM panorama of postcompression JA2 grain sample...19 Fig. 37 SEM panorama of postcompression JA2 grain sample (uniaxially compressed at a rate of ~100 s–1, 60 °C, and strain

A population-specific Mini-Nutritional Assessment can effectively grade the nutritional status of stroke rehabilitation patients in Taiwan.

PubMed

Tsai, Alan C; Shih, Chi-Ling

2009-01-01

To determine whether a modified version of the Mini-Nutritional Assessment without body mass index could effectively assess the nutritional risk status of stroke rehabilitation patients in Taiwan. The Mini-Nutritional Assessment was developed on the basis of clinical data of Western populations. Although widely used, its application to assess stroke rehabilitation patients has been limited. Further, to get best results, population-specific modifications to address anthropometric and lifestyle differences have been suggested, especially for non-Caucasian populations. The study assessed the nutritional status of stroke rehabilitation patients who enrolled in the Long-Term Care Service of Taipei. Strokes who were >40 years old, in the program for >1 month and cognitively able to answer the questions were recruited to participate in the study. An on-site in-person interview with structured questionnaire elicited information on personal data, disease history and healthcare use and answers to the Mini-Mental State Examination, the Activities of Daily Living and the Mini-Nutritional Assessment. Patient's nutritional status was assessed with the Mini-Nutritional Assessment in three versions: the original, population-specific (MNA-TI) and population-specific, without body mass index (MNA-TII). The original Mini-Nutritional Assessment rated 24% of patients malnourished and 57% at risk of malnutrition. Similar results, 14 and 64%, respectively, for MNA-TI; and 19 and 57%, respectively, for MNA-TII were observed. Both the original and the modified versions of the Mini-Nutritional Assessment can effectively rate the nutritional risk status of stroke rehabilitation patients in Taiwan. Version MNA-TII that adopted population-specific anthropometric cut-values but without body mass index can effectively predict the nutritional status of stroke patients. The modified scale (MNA-TII) can enhance the application of the tool and timely detection and intervention of undernutrition

The October 2014 United States Treasury bond flash crash and the contributory effect of mini flash crashes

PubMed Central

Levine, Zachary S.; Floridi, Luciano

2017-01-01

We investigate the causal uncertainty surrounding the flash crash in the U.S. Treasury bond market on October 15, 2014, and the unresolved concern that no clear link has been identified between the start of the flash crash at 9:33 and the opening of the U.S. equity market at 9:30. We consider the contributory effect of mini flash crashes in equity markets, and find that the number of equity mini flash crashes in the three-minute window between market open and the Treasury Flash Crash was 2.6 times larger than the number experienced in any other three-minute window in the prior ten weekdays. We argue that (a) this statistically significant finding suggests that mini flash crashes in equity markets both predicted and contributed to the October 2014 U.S. Treasury Bond Flash Crash, and (b) mini-flash crashes are important phenomena with negative externalities that deserve much greater scholarly attention. PMID:29091931

Deployable Mini-Payload Missions Enabled by Small Radioisotope Power Systems (RPSs)

NASA Technical Reports Server (NTRS)

Abelson, Robert D.; Satter, Celeste M.

2005-01-01

Deployable mini-payloads are envisioned as small, simple, standalone instruments that could be deployed from a mother vehicle such as a rover or the proposed Jupiter Icy Moons Orbiter to key points of interest within the solar system. Used in conjunction with a small radioisotope power system (RPS), these payloads could potentially be used for long-duration science missions or as positional beacons for rovers or other spacecraft. The RPS power source would be suitable for deployable mini-payload missions that would take place anywhere there is limited, intermittent, or no solar insolation. This paper introduces two such concepts: (1) a seismic monitoring station deployed by a rover or aerobot, and (2) a passive fields and particles station delivered by a mother spacecraft to Jupiter.

The High-Level Interface Definitions in the ASTRI/CTA Mini Array Software System (MASS)

NASA Astrophysics Data System (ADS)

Conforti, V.; Tosti, G.; Schwarz, J.; Bruno, P.; Cefal‘A, M.; Paola, A. D.; Gianotti, F.; Grillo, A.; Russo, F.; Tanci, C.; Testa, V.; Antonelli, L. A.; Canestrari, R.; Catalano, O.; Fiorini, M.; Gallozzi, S.; Giro, E.; Palombara, N. L.; Leto, G.; Maccarone, M. C.; Pareschi, G.; Stringhetti, L.; Trifoglio, M.; Vercellone, S.; Astri Collaboration; Cta Consortium

2015-09-01

ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) is a Flagship Project funded by the Italian Ministry of Education, University and Research, and led by INAF, the Italian National Institute of Astrophysics. Within this framework, INAF is currently developing an end-to-end prototype, named ASTRI SST-2M, of a Small Size Dual-Mirror Telescope for the Cherenkov Telescope Array, CTA. A second goal of the project is the realization of the ASTRI/CTA mini-array, which will be composed of seven SST-2M telescopes placed at the CTA Southern Site. The ASTRI Mini Array Software System (MASS) is designed to support the ASTRI/CTA mini-array operations. MASS is being built on top of the ALMA Common Software (ACS) framework, which provides support for the implementation of distributed data acquisition and control systems, and functionality for log and alarm management, message driven communication and hardware devices management. The first version of the MASS system, which will comply with the CTA requirements and guidelines, will be tested on the ASTRI SST-2M prototype. In this contribution we present the interface definitions of the MASS high level components in charge of the ASTRI SST-2M observation scheduling, telescope control and monitoring, and data taking. Particular emphasis is given to their potential reuse for the ASTRI/CTA mini-array.

Generation of sequence signatures from DNA amplification fingerprints with mini-hairpin and microsatellite primers.

PubMed

Caetano-Anollés, G; Gresshoff, P M

1996-06-01

DNA amplification fingerprinting (DAF) with mini-hairpins harboring arbitrary "core" sequences at their 3' termini were used to fingerprint a variety of templates, including PCR products and whole genomes, to establish genetic relationships between plant tax at the interspecific and intraspecific level, and to identify closely related fungal isolates and plant accessions. No correlation was observed between the sequence of the arbitrary core, the stability of the mini-hairpin structure and DAF efficiency. Mini-hairpin primers with short arbitrary cores and primers complementary to simple sequence repeats present in microsatellites were also used to generate arbitrary signatures from amplification profiles (ASAP). The ASAP strategy is a dual-step amplification procedure that uses at least one primer in each fingerprinting stage. ASAP was able to reproducibly amplify DAF products (representing about 10-15 kb of sequence) following careful optimization of amplification parameters such as primer and template concentration. Avoidance of primer sequences partially complementary to DAF product termini was necessary in order to produce distinct fingerprints. This allowed the combinatorial use of oligomers in nucleic acid screening, with numerous ASAP fingerprinting reactions based on a limited number of primer sequences. Mini-hairpin primers and ASAP analysis significantly increased detection of polymorphic DNA, separating closely related bermudagrass (Cynodon) cultivars and detecting putatively linked markers in bulked segregant analysis of the soybean (Glycine max) supernodulation (nitrate-tolerant symbiosis) locus.

Psychometric Properties of the Folstein Mini-Mental State Examination

ERIC Educational Resources Information Center

Lopez, Michael N.; Charter, Richard A.; Mostafavi, Beeta; Nibut, Lorraine P.; Smith, Whitney E.

2005-01-01

Criterion-referenced (Livingston) and norm-referenced (Gilmer-Feldt) techniques were used to measure the internal consistency reliability of Folsteins Mini-Mental State Examination (MMSE) on a large sample (N = 418) of elderly medical patients. Two administration and scoring variants of the MMSE Attention and Calculation section (Serial 7s only…

Comparison of the effects of mini-implant and traditional anchorage on patients with maxillary dentoalveolar protrusion.

PubMed

Xu, Yanhua; Xie, Jiye

2017-03-01

To compare the treatment effects of mini-implants as anchor units with conventional methods of anchorage reinforcement in maxillary dentoalveolar protrusion patients in terms of skeletal, dental, and soft tissue changes. We searched the databases of the Cochrane Library, PubMed, OVIDSP, CBM, VIP, WanFang Data, and CNKI covering December 1966 to March 2016 for randomized controlled trials (RCTs) and clinical controlled trials that compared the treatment effects of mini-implants with conventional anchorage reinforcement in maxillary dentoalveolar protrusion patients. Literature filtering, data extraction, and methodological quality evaluation were finished independently by two researchers and disagreements were solved by discussion. Meta-analysis was performed when possible; otherwise descriptive assessment was done. Through a predefined search strategy, we finally included 14 eligible studies. Eight outcomes were evaluated in this study: maxillary incisor retraction, maxillary molar movement, U1-SN, SNA, SN-MP, UL-E Plane, NLA and G-Sn-Pg. Mini-implant anchorage was more effective in retracting the anterior teeth, produced less anchorage loss, and had a greater effect on SN-MP for the high-angle patients than did traditional anchorage. Both mini-implants and traditional anchorage underwent decreases in on U1-SN and SNA. More qualified RCTs are required to make reliable recommendations about the anchorage capacity of mini-implant and traditional anchorage in patients with maxillary dentoalveolar protrusion, especially on the UL-E plane, NLA, and G-Sn-Pg.

Mini-Union Catalogs: Sharing Titles in Indexes to Anthologies and Collections.

ERIC Educational Resources Information Center

Parker, J. Carlyle

1980-01-01

Recommends that librarians locally develop mini-union catalogs to provide for increased access to library materials and to facilitate interlibrary loan. Practical instruction is provided for the preparation of such catalogs. (RAA)

Temporary anchorage devices (TADs) in orthodontics: review of the factors that influence the clinical success rate of the mini-implants.

PubMed

Leo, M; Cerroni, L; Pasquantonio, G; Condò, S G; Condò, R

2016-01-01

The mini-implant, temporary anchorage devices (TADS), are now a common method of treatment in Orthodontics with versatility, minimal invasiveness and the relationship between costs and benefits that they offer even today. Skeletal anchorage has, to a large degree, replaced conventional anchorage in situations where anchorage is considered either critical, insufficient, or likely to result in undesirable side effects such as vertical displacements generated by inter-maxillary force systems. The objective of this study is to carry out a review about the factors that seem affect the success or failure rate of orthodontic mini-implants. A computerized literature review was performed by searching the MEDLINE database (Entrez PubMed, www.ncbi.nlm.nih.gov), Google Scholar, Scopus, Cochrane Central Register of Controlled Trials, Isi Web of Knowledge until March 2016 . The main subject heading "orthodontics" was combined with these keywords mini-implant, mini-screw, micro-implants, mini-implant success rate, mini-implant failure rate, skeletal anchorage, temporary anchorage device (TADS). In the selection process, abstracts were initially read independently by two researchers to identify potentially eligible full text papers which were then retrieved and assessed in order to decide on the final inclusion. The clinical success of orthodontic anchorage by mini-implants depends on the stability of the miniscrews used for fixation. For good stability, the application site must provide bone of good quantity and quality. We can reasonably assume that the stability of the anchorage of the mini-implants could be optimized by selecting a position with particular characteristics of quality and quantity of bone, in relation to cortical and total mandibular and jaw bone thickness. These expected informations are important because they indicates that the bone quality and quantity are significant when considering an implant placement site, but also that there are other confounding

Status of the core and the mini core collections for the U.S. gemrplasm collection of peanut

USDA-ARS?s Scientific Manuscript database

To maximize their usefulness, core and mini core collections should be dynamic. The peanut core collection was developed in the early 1990's, and the mini core was developed in the late 1990's. Research has shown that these collections can be used to improve the efficiency and effectiveness of ide...

Developments in Miniaturized Laser Heterodyne Radiometer (mini-LHR) construction for groundtruth measurements of CH4 and CO2 in harsh terrain

NASA Astrophysics Data System (ADS)

DiGregorio, A.; Wilson, E. L.; Hoffman, C.; Grunberg, C.; Mao, J.; Ramanathan, A. K.

2016-12-01

We present an updated, ruggedized design of NASA Goddard Space Flight Center's Miniaturized Laser Heterodyne Radiometer (mini-LHR), and the results of testing in the Bonanza Creek Research Forest. The mini-LHR is a passive variation of typical heterodyne radiometry instruments, designed to work in tandem with the AERONET sun photometer for collection of column methane (CH4) and carbon dioxide (CO2) in harsh environments. Advancements in the development of the Cube-Sat version of the mini-LHR have allowed a more than 50% reduction in size, weight, and power usage of the mini-LHR. Now small enough to fit in a medium handbag, the mini-LHR can be run off of a small 35 Watt solar panel and backup battery for continuous measurement. Using a touch-screen control interface built off of a Raspberry Pi, the updated mini-LHR is capable of data collection and preliminary data processing, even without internet, cellular, or satellite connectivity. The improvements made to the mini-LHR were tested in a field campaign in May 2016 funded under NASA's IDS program to track CH4 and CO2 emissions above thawing permafrost. In addition to being a comprehensive study of methane release from thawing permafrost, this pilot study tested the ruggedization and functionality of the instrument in three different environments- a black spruce forest, collapsed scar bog, and fen.

Materials identification using a small-scale pixellated x-ray diffraction system

NASA Astrophysics Data System (ADS)

O'Flynn, D.; Crews, C.; Drakos, I.; Christodoulou, C.; Wilson, M. D.; Veale, M. C.; Seller, P.; Speller, R. D.

2016-05-01

A transmission x-ray diffraction system has been developed using a pixellated, energy-resolving detector (HEXITEC) and a small-scale, mains operated x-ray source (Amptek Mini-X). HEXITEC enables diffraction to be measured without the requirement of incident spectrum filtration, or collimation of the scatter from the sample, preserving a large proportion of the useful signal compared with other diffraction techniques. Due to this efficiency, sufficient molecular information for material identification can be obtained within 5 s despite the relatively low x-ray source power. Diffraction data are presented from caffeine, hexamine, paracetamol, plastic explosives and narcotics. The capability to determine molecular information from aspirin tablets inside their packaging is demonstrated. Material selectivity and the potential for a sample classification model is shown with principal component analysis, through which each different material can be clearly resolved.

Validation of the Mini-OAKHQOL for use in patients with osteoarthritis in Spain.

PubMed

Gonzalez Sáenz de Tejada, Marta; Bilbao, Amaia; Herrera, Carmen; García, Lidia; Sarasqueta, Cristina; Escobar, Antonio

2017-08-01

The Mini-Osteoarthritis Knee and Hip Quality of Life (Mini-OAKHQOL) questionnaire osteoarthritis is specific to individuals with knee or hip osteoarthritis. The objective of this study was to perform a validation of the Mini-OAKHQOL for use in Spain in terms of its psychometric properties of reliability, validity and responsiveness. Patients with osteoarthritis from the waiting list for a joint replacement completed the OAKHQOL, Short Form 36 Health Survey and Western Ontario and McMaster Universities Osteoarthritis Index. Reliability was assessed in terms of internal consistency and test-retest data, and convergent validity using Spearman's correlation coefficient. Structural validity was investigated by confirmatory factor analysis, and Rasch analysis was used to examine the unidimensionality of the scales. Responsiveness was assessed by calculating effect sizes. Confirmatory factor analysis confirmed the five-factor model, and the results of the Rasch analyses supported the unidimensionality assumption, with infit and outfit statistics. Cronbach's alpha ranged from 0.76 to 0.89 for all except the social dimensions. Statistically significant differences were observed between patients with different degrees of disease severity on all dimensions. There was convergent validity among dimensions expected to be correlated. The OAKHQOL questionnaire showed good responsiveness, with large changes for all dimensions apart from the two social dimensions, which had small effect sizes. Results of the study support the view that the Spanish version of the Mini-OAKHQOL questionnaire is a valid instrument to measure health-related quality of life in patients with osteoarthritis of the lower limb.

Mandibular molar uprighting using mini-implants: different approaches for different clinical cases--two case reports.

PubMed

Derton, Nicola; Perini, Alessandro; Mutinelli, Sabrina; Gracco, Antonio

2012-01-01

To detail two different clinical protocols and case studies using mini-implant anchorage developed to respond to certain clinical conditions. Two clinical protocols are described to upright mesially tilted mandibular molars. In the first protocol, a single mini-implant is inserted distally to the molar to be uprighted, and an elastic traction chain is applied to the tooth. In the second clinical approach, two mini-implants are inserted mesially. A screw-suspended TMA sectional archwire is applied (Derton-Perini technique). Two cases, descriptive of the two different treatment protocols, are described. In the first case, the mandibular right second premolar was missing and the adjacent first molar needed to be uprighted. A single screw was inserted distally to the first molar, and an elastic chain was applied. In the second case, the mandibular left second molar was missing and the third molar needed to be uprighted. Two mini-implants were inserted mesially and a fully screw-supported sectional archwire was used to upright and bodily mesialize the third molar. Both uprighting approaches uprighted the molar axis without loss of anchorage. The two approaches to mandibular molar uprighting, developed as rational responses to different clinical cases, were both found to be effective.

Actividades al Aire Libre (Outdoor Activities). OBIS/Mini-Corps.

ERIC Educational Resources Information Center

California Univ., Berkeley. Lawrence Hall of Science.

Prepared specifically for use in one-week outdoor summer camp programs for migrant children aged 10-15, the twenty bilingual (Spanish and English) educational and recreational activities in the Outdoor Biology Instructional Strategies (OBIS)/Mini-Corps package have been revised to develop language skills as well as an awareness of the outdoor…

Environmental Education [30 Instructional Mini-units for K-6].

ERIC Educational Resources Information Center

Minnesota State Dept. of Education, St. Paul.

These 30 self-contained instructional units, for K-6, are structured to promote learning exercises outside the classroom; from the playground, local factory, or city hall to pond, farm, or woodland, places where students may touch the pulse of community life. Attractively packaged in plastic folders, each "mini-unit" provides a teacher's guide…

Design of a nuclear isotope heat source assembly for a spaceborne mini-Brayton power module.

NASA Technical Reports Server (NTRS)

Wein, D.; Gorland, S. H.

1973-01-01

Results of a study to develop a feasible design definition of a heat source assembly (HSA) for use in nominal 500-, 1200-, or 2000-W(e) mini-Brayton spacecraft power systems. The HSA is a modular design which is used either as a single unit to provide thermal energy to the 500-W(e) mini-Brayton power module or in parallel with one or two additional HSAs for the 1200- or 2000-W(e) power module systems. Principal components consist of a multihundred watt RTG isotope heat source, a heat source heat exchanger which transfers the thermal energy from the heat source to the mini-Brayton power conversion system, an auxiliary cooling system which provides requisite cooling during nonoperation of the power conversion module and an emergency cooling system which precludes accidental release of isotope fuel in the event of system failure.

Construction of trypanosome artificial mini-chromosomes.

PubMed Central

Lee, M G; E, Y; Axelrod, N

1995-01-01

We report the preparation of two linear constructs which, when transformed into the procyclic form of Trypanosoma brucei, become stably inherited artificial mini-chromosomes. Both of the two constructs, one of 10 kb and the other of 13 kb, contain a T.brucei PARP promoter driving a chloramphenicol acetyltransferase (CAT) gene. In the 10 kb construct the CAT gene is followed by one hygromycin phosphotransferase (Hph) gene, and in the 13 kb construct the CAT gene is followed by three tandemly linked Hph genes. At each end of these linear molecules are telomere repeats and subtelomeric sequences. Electroporation of these linear DNA constructs into the procyclic form of T.brucei generated hygromycin-B resistant cell lines. In these cell lines, the input DNA remained linear and bounded by the telomere ends, but it increased in size. In the cell lines generated by the 10 kb construct, the input DNA increased in size to 20-50 kb. In the cell lines generated by the 13 kb constructs, two sizes of linear DNAs containing the input plasmid were detected: one of 40-50 kb and the other of 150 kb. The increase in size was not the result of in vivo tandem repetitions of the input plasmid, but represented the addition of new sequences. These Hph containing linear DNA molecules were maintained stably in cell lines for at least 20 generations in the absence of drug selection and were subsequently referred to as trypanosome artificial mini-chromosomes, or TACs. Images PMID:8532534

Transplant Image Processing Technology under Windows into the Platform Based on MiniGUI

NASA Astrophysics Data System (ADS)

Gan, Lan; Zhang, Xu; Lv, Wenya; Yu, Jia

MFC has a large number of digital image processing-related API functions, object-oriented and class mechanisms which provides image processing technology strong support in Windows. But in embedded systems, image processing technology dues to the restrictions of hardware and software do not have the environment of MFC in Windows. Therefore, this paper draws on the experience of image processing technology of Windows and transplants it into MiniGUI embedded systems. The results show that MiniGUI/Embedded graphical user interface applications about image processing which used in embedded image processing system can be good results.

Resolution of puzzles from the LSND, KARMEN, and MiniBooNE experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gninenko, S. N.

2011-01-01

This work has attempted to reconcile puzzling neutrino oscillation results from the LSND, KARMEN, and MiniBooNE experiments. We show that the LSND evidence for {nu}{sub {mu}}{yields}{nu}e oscillations, its long-standing disagreement with the results from KARMEN, and the anomalous event excess observed by MiniBooNE in {nu}{sub {mu}} and {nu}{sub {mu}} data could all be explained by the existence of a heavy sterile neutrino ({nu}{sub h}). All these results are found to be consistent with each other, assuming that the {nu}{sub h} is created in {nu}{sub {mu}} neutral-current interactions and decays radiatively into a photon and a light neutrino. Assuming the {nu}{submore » h} is produced through mixing with {nu}{sub {mu}}, the combined analysis of the LSND and MiniBooNe excess events suggests that the {nu}{sub h} mass is in the range from 40 to 80 MeV, the mixing strength is |U{sub {mu}h}|{sup 2{approx_equal}}10{sup -3}-10{sup -2}, and the lifetime is {tau}{sub {nu}{sub h}} < or approx. 10{sup -9} s. Surprisingly, this LSND-MiniBooNE parameter window is found to be unconstrained by the results from the most sensitive experiments. We set new limits on |U{sub {mu}h}|{sup 2} for the favorable mass region from the precision measurements of the Michel spectrum by the TWIST experiment. The results obtained provide a strong motivation for a sensitive search for the {nu}{sub h} in a near future K decay or neutrino experiments, which fit well in the existing and planned experimental programs at CERN or FNAL. The question of whether the heavy neutrino is a Dirac or Majorana particle is briefly discussed.« less

A Comparison of Image Quality and Radiation Exposure Between the Mini C-Arm and the Standard C-Arm.

PubMed

van Rappard, Juliaan R M; Hummel, Willy A; de Jong, Tijmen; Mouës, Chantal M

2018-04-01

The use of intraoperative fluoroscopy has become mandatory in osseous hand surgery. Due to its overall practicality, the mini C-arm has gained popularity among hand surgeons over the standard C-arm. This study compares image quality and radiation exposure for patient and staff between the mini C-arm and the standard C-arm, both with flat panel technology. An observer-based subjective image quality study was performed using a contrast detail (CD) phantom. Five independent observers were asked to determine the smallest circles discernable to them. The results were plotted in a graph, forming a CD curve. From each curve, an image quality figure (IQF) was derived. A lower IQF equates to a better image quality. The patients' entrance skin dose was measured, and to obtain more information about the staff exposure dose, a perspex hand phantom was used. The scatter radiation was measured at various distances and angles relative to a central point on the detector. The IQF was significantly lower for the mini C-arm resulting in a better image quality. The patients' entrance dose was 10 times higher for the mini C-arm as compared with the standard C-arm, and the scatter radiation threefold. Due to its improved image quality and overall practicality, the mini C-arm is recommended for hand surgical procedures. To ensure that the surgeons' radiation exposure is not exceeding the safety limits, monitoring radiation exposure using mini C-arms with flat panel technology during surgery should be done in a future clinical study.

Long-term changes in ozone mini-hole event frequency over the Northern Hemisphere derived from ground-based measurements

NASA Astrophysics Data System (ADS)

Krzycin, Janusz W.

2002-10-01

Decadal changes of ozone mini-hole event appearance over the Northern Hemisphere midlatitudes are examined based on daily total ozone data from seven stations having long records (four decades or more) of ozone observations. The various threshold methods for accepting and rejecting the ozone minima as mini-holes are examined. Mini-hole event activity is seen to be rather stable when averaged over a decadal time scale if the mini-holes are selected as large negative departures (exceeding 20%) relative to the moving long-term total ozone reference. The results are compared with a previous ozone mini-hole climatology derived from satellite data (TOMS measurements on board the Nimbus-7 satellite for the period 1978-93). A nonlinear statistical model (MARS), which takes into account various total ozone dynamical proxies (from NCEP-NCAR reanalysis), is used to study dynamical factors responsible for the ozone extremes over Arosa in the period 1950-99. The model explains as much as 95% of the total variance of the ozone extremes. The model-observation differences averaged over the decadal intervals are rather smooth throughout the whole period analysed. It is suggested that the short-term dynamical processes controlling the appearance of ozone extremes influenced the ozone field in a similar way before and after the onset of abrupt ozone depletion in the early 1980s. The analysis of the ozone profile and the tropopause pressure (from the ozonesondings over Hohenpeissenberg, 1966-99) during mini-hole events shows 60% ozone reduction in the lower stratosphere and an approximately 50 hPa upward shift of the thermal tropopause there.

Comparison of the Mini-Balance Evaluations Systems Test with the Berg Balance Scale in relationship to walking speed and motor recovery post stroke.

PubMed

Madhavan, Sangeetha; Bishnoi, Alka

2017-12-01

The Mini-BESTest is a recently developed balance assessment tool that incorporates challenging dynamic balance tasks. Few studies have compared the psychometric properties of the Mini-BESTest to the commonly used Berg Balance Scale (BBS). However, the utility of these scales in relationship to post stroke walking speeds has not been explored. The purpose of this study was to compare the sensitivity and specificity of the Mini-BESTest and BBS to evaluate walking speeds in individuals with stroke. A retrospective exploratory design. Forty-one individuals with chronic stroke were evaluated with the Mini-BESTest, BBS, and 10-meter self-selected walk test (10MWT). Based on their self-selected gait speeds (below or above 0.8 m/s), participants were classified as slow and fast walkers. Significant linear correlations were observed between the Mini-BESTest vs. BBS (r = 0.72, p ≤ 0.001), Mini-BESTest vs. 10MWT (r = 0.58, p ≤ 0.001), and BBS vs. 10MWT (r = 0.30, p = 0.05). Independent t-tests comparing the balance scores for the slow and fast walkers revealed significant group differences for the Mini-BESTest (p = 0.003), but not for the BBS (p = 0.09). The Mini-BESTest demonstrated higher sensitivity (93%) and specificity (64%) compared to the BBS (sensitivity 81%, specificity 56%) for discriminating participants into slow and fast walkers. The Mini-BESTest has a greater discriminative ability than the BBS to categorize individuals with stroke into slow and fast walkers.

Clinical Performance of a New Bitangential Mini-scleral Lens.

PubMed

Otten, Henny M; van der Linden, Bart J J J; Visser, Esther-Simone

2018-06-01

New bitangential mini-scleral lens designs provide a highly precise fit, follow the scleral shape, are comfortable to wear, and can correct residual astigmatism. This new scleral lens design complements the arsenal of medical contact lenses available to eye care practitioners. The aim of this study was to evaluate the subjective and objective performance of a new mini-scleral lens design with a bitangential periphery. In this observational study, data were collected for up to 15 months (median, 84 days; interquartile range, 76 days) from the left eyes of 133 patients fitted with this newly designed lens. Data were recorded during regular visits at Visser Contact Lens Practice's scleral lens clinics: diagnosis, clinical indication for scleral lenses, previous contact lens type, subjective performance, horizontal visible iris diameter, corrected distance visual acuity, and scleral lens fitting characteristics. The most common indication was keratoconus (45%), followed by irregular astigmatism (22%), keratoplasty (16.5%), ocular surface disease (13.5%), and other forms of irregular astigmatism (3%). The majority of patients (79%) scored comfort as either a 4 or 5 (out of 5), and 82% wore their lenses 12 hours or longer a day. Most lenses (81%) had a diameter of 16 mm (median, 16 mm; range, 15.5 to 17 mm) and were composed of Boston XO2 (46%), Menicon Z (44%), Boston XO (9%), or Boston Equalens II (1%). The median corrected distance visual acuity was 0.022 logarithm of the minimal angle of resolution (interquartile range, 0.155). The fitting characteristics revealed optimal values for centration and movement in 91% and 83%, respectively. Finally, the median stabilization axis was 50 degrees. New mini-scleral lenses with bitangential peripheral geometry yield satisfactory clinical results and good subjective performance and are therefore an effective option for managing patients who have irregular astigmatism or other corneal pathology.

Evaluation of Progress, Bilingual Mini-Head Start, November 1973.

ERIC Educational Resources Information Center

McConnell, Beverly

A 5-year experimental project, the Bilingual Mini Head Start program is an early education program for children of migrant farm workers. The program has 2 components: the mobile and the stationary components. In the stationary program, 2 year-round centers are operated in Connell and Moses Lake (Washington). These centers' purpose is to…

Mini-beam collimator applications at the Advanced Photon Source

NASA Astrophysics Data System (ADS)

Xu, Shenglan; Keefe, Lisa J.; Mulichak, Anne; Yan, Lifen; Alp, Ercan E.; Zhao, Jiyong; Fischetti, Robert F.

2011-09-01

In 2007, the General Medicine and Cancer Institutes Collaborative Access Team (GM/CA CAT, Sector 23, Advanced Photon Source) began providing mini-beam collimators to its users. These collimators contained individual, 5- or 10-μm pinholes and were rapidly exchangeable, thereby allowing users to tailor the beam size to their experimental needs. The use of these collimators provided a reduction in background noise, and thus improved the signal-to-noise ratio [1,2]. Recent improvements in the collimator design include construction of the device from a monolithic piece of molybdenum with multiple pinholes mounted inside [3]. This allows users to select from various size options from within the beamline control software without the realignment that was previously necessary. In addition, a new, 20-μm pinhole has been added to create a "quad-collimator", resulting in greater flexibility for the users. The mini-beam collimator is now available at multiple crystallographic beamlines and also is a part of the first Mössbauer Microscopic system at sector 3-ID.

Histomorphometric Evaluation of the Effects of Various Diode Lasers and Force Levels on Orthodontic Mini Screw Stability

PubMed Central

Isman, Eren; Taner, Lale; Kurkcu, Mehmet

2015-01-01

Abstract Objective The purpose of this study was to evaluate the effects of different laser dose and force levels on the stability of orthodontic mini screws used for anchorage, by histomorphometric analyses. Background data Low-level laser therapy speeds up blood flow, improves the mechanism of the revitalization processes, reduces the risk of infection, boosts metabolic activities, and accelerates the healing of the damaged tissue. Although there are many research studies about low-level laser therapy applications in a variety of areas, no investigations were found concerning mini screw stability using various laser dose levels with different force level applications. Methods Seventeen New Zealand white rabbits were used. A total of 68 cylindrical, self-drilling orthodontic mini screws were threaded at the fibula. Experimental subjects were divided into six groups; force application was not performed in the first three groups, whereas 150g of force was applied via nickel-titanium closed-coil springs placed between two mini screws in the other three groups. Measurements of the initial torque values (10 Ncm) were manipulated by a digital portable torque gauge. Various low-level laser doses were applied to the groups during the postoperative 10 days. After 4 weeks, bone-to-implant contact and cortical bone thickness were histomorphometrically analyzed. Results In the 150g force plus 20 J/cm2 dosage group, the highest bone-to-implant contact values were observed. (p<0.05) There were no statistically significant correlations between cortical bone thickness and bone-to-implant contact values; on the other hand, no significant difference was found among the same groups in terms of cortical bone thickness values (p>0.05). Conclusions Low-level laser therapy was noticed to induce the mini screw–bone contact area. Low-level laser therapy may be a supplementary treatment method to increase the stability of the orthodontic mini screw. PMID:25594769

Dark Matter Search in a Proton Beam Dump with MiniBooNE

NASA Astrophysics Data System (ADS)

Aguilar-Arevalo, A. A.; Backfish, M.; Bashyal, A.; Batell, B.; Brown, B. C.; Carr, R.; Chatterjee, A.; Cooper, R. L.; deNiverville, P.; Dharmapalan, R.; Djurcic, Z.; Ford, R.; Garcia, F. G.; Garvey, G. T.; Grange, J.; Green, J. A.; Huelsnitz, W.; de Icaza Astiz, I. L.; Karagiorgi, G.; Katori, T.; Ketchum, W.; Kobilarcik, T.; Liu, Q.; Louis, W. C.; Marsh, W.; Moore, C. D.; Mills, G. B.; Mirabal, J.; Nienaber, P.; Pavlovic, Z.; Perevalov, D.; Ray, H.; Roe, B. P.; Shaevitz, M. H.; Shahsavarani, S.; Stancu, I.; Tayloe, R.; Taylor, C.; Thornton, R. T.; Van de Water, R.; Wester, W.; White, D. H.; Yu, J.; MiniBooNE-DM Collaboration

2017-06-01

The MiniBooNE-DM Collaboration searched for vector-boson mediated production of dark matter using the Fermilab 8-GeV Booster proton beam in a dedicated run with 1.86 ×1 020 protons delivered to a steel beam dump. The MiniBooNE detector, 490 m downstream, is sensitive to dark matter via elastic scattering with nucleons in the detector mineral oil. Analysis methods developed for previous MiniBooNE scattering results were employed, and several constraining data sets were simultaneously analyzed to minimize systematic errors from neutrino flux and interaction rates. No excess of events over background was observed, leading to a 90% confidence limit on the dark matter cross section parameter, Y =ɛ2αD(mχ/mV)4≲10-8 , for αD=0.5 and for dark matter masses of 0.01

Dark Matter Search in a Proton Beam Dump with MiniBooNE

DOE PAGES

Aguilar-Arevalo, A. A.; Backfish, M.; Bashyal, A.; ...

2017-05-31

The MiniBooNE-DM Collaboration searched for vector-boson mediated production of dark matter using the Fermilab 8-GeV Booster proton beam in a dedicated run with 1.86 × 10 20 protons delivered to a steel beam dump. The MiniBooNE detector, 490 m downstream, is sensitive to dark matter via elastic scattering with nucleons in the detector mineral oil. Analysis methods developed for previous MiniBooNE scattering results were employed, and several constraining data sets were simultaneously analyzed to minimize systematic errors from neutrino flux and interaction rates. No excess of events over background was observed, leading to a 90% confidence limit on the darkmore » matter cross section parameter, Y = ε 2α D(m χ/m V) 4≲10 –8, for α D = 0.5 and for dark matter masses of 0.01 < m χ < 0.3 GeV in a vector portal model of dark matter. This is the best limit from a dedicated proton beam dump search in this mass and coupling range and extends below the mass range of direct dark matter searches. Here, these results demonstrate a novel and powerful approach to dark matter searches with beam dump experiments.« less

Dark Matter Search in a Proton Beam Dump with MiniBooNE.

PubMed

Aguilar-Arevalo, A A; Backfish, M; Bashyal, A; Batell, B; Brown, B C; Carr, R; Chatterjee, A; Cooper, R L; deNiverville, P; Dharmapalan, R; Djurcic, Z; Ford, R; Garcia, F G; Garvey, G T; Grange, J; Green, J A; Huelsnitz, W; de Icaza Astiz, I L; Karagiorgi, G; Katori, T; Ketchum, W; Kobilarcik, T; Liu, Q; Louis, W C; Marsh, W; Moore, C D; Mills, G B; Mirabal, J; Nienaber, P; Pavlovic, Z; Perevalov, D; Ray, H; Roe, B P; Shaevitz, M H; Shahsavarani, S; Stancu, I; Tayloe, R; Taylor, C; Thornton, R T; Van de Water, R; Wester, W; White, D H; Yu, J

2017-06-02

The MiniBooNE-DM Collaboration searched for vector-boson mediated production of dark matter using the Fermilab 8-GeV Booster proton beam in a dedicated run with 1.86×10^{20} protons delivered to a steel beam dump. The MiniBooNE detector, 490 m downstream, is sensitive to dark matter via elastic scattering with nucleons in the detector mineral oil. Analysis methods developed for previous MiniBooNE scattering results were employed, and several constraining data sets were simultaneously analyzed to minimize systematic errors from neutrino flux and interaction rates. No excess of events over background was observed, leading to a 90% confidence limit on the dark matter cross section parameter, Y=ε^{2}α_{D}(m_{χ}/m_{V})^{4}≲10^{-8}, for α_{D}=0.5 and for dark matter masses of 0.01

Dark Matter Search in a Proton Beam Dump with MiniBooNE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aguilar-Arevalo, A. A.; Backfish, M.; Bashyal, A.

The MiniBooNE-DM Collaboration searched for vector-boson mediated production of dark matter using the Fermilab 8-GeV Booster proton beam in a dedicated run with 1.86 × 10 20 protons delivered to a steel beam dump. The MiniBooNE detector, 490 m downstream, is sensitive to dark matter via elastic scattering with nucleons in the detector mineral oil. Analysis methods developed for previous MiniBooNE scattering results were employed, and several constraining data sets were simultaneously analyzed to minimize systematic errors from neutrino flux and interaction rates. No excess of events over background was observed, leading to a 90% confidence limit on the darkmore » matter cross section parameter, Y = ε 2α D(m χ/m V) 4≲10 –8, for α D = 0.5 and for dark matter masses of 0.01 < m χ < 0.3 GeV in a vector portal model of dark matter. This is the best limit from a dedicated proton beam dump search in this mass and coupling range and extends below the mass range of direct dark matter searches. Here, these results demonstrate a novel and powerful approach to dark matter searches with beam dump experiments.« less

Reliable and accurate CD4+ T cell count and percent by the portable flow cytometer CyFlow MiniPOC and "CD4 Easy Count Kit-Dry", as revealed by the comparison with the gold standard dual platform technology.

PubMed

Nasi, Milena; De Biasi, Sara; Bianchini, Elena; Gibellini, Lara; Pinti, Marcello; Scacchetti, Tiziana; Trenti, Tommaso; Borghi, Vanni; Mussini, Cristina; Cossarizza, Andrea

2015-01-01

An accurate and affordable CD4+ T cells count is an essential tool in the fight against HIV/AIDS. Flow cytometry (FCM) is the "gold standard" for counting such cells, but this technique is expensive and requires sophisticated equipment, temperature-sensitive monoclonal antibodies (mAbs) and trained personnel. The lack of access to technical support and quality assurance programs thus limits the use of FCM in resource-constrained countries. We have tested the accuracy, the precision and the carry-over contamination of Partec CyFlow MiniPOC, a portable and economically affordable flow cytometer designed for CD4+ count and percentage, used along with the "CD4% Count Kit-Dry". Venous blood from 59 adult HIV+ patients (age: 25-58 years; 43 males and 16 females) was collected and stained with the "MiniPOC CD4% Count Kit-Dry". CD4+ count and percentage were then determined in triplicate by the CyFlow MiniPOC. In parallel, CD4 count was performed using mAbs and a CyFlow Counter, or by a dual platform system (from Beckman Coulter) based upon Cytomic FC500 ("Cytostat tetrachrome kit" for mAbs) and Coulter HmX Hematology Analyzer (for absolute cell count). The accuracy of CyFlow MiniPOC against Cytomic FC500 showed a correlation coefficient (CC) of 0.98 and 0.97 for CD4+ count and percentage, respectively. The accuracy of CyFlow MiniPOC against CyFlow Counter showed a CC of 0.99 and 0.99 for CD4 T cell count and percentage, respectively. CyFlow MiniPOC showed an excellent repeatability: CD4+ cell count and percentage were analyzed on two instruments, with an intra-assay precision below ± 5% deviation. Finally, there was no carry-over contamination for samples at all CD4 values, regardless of their position in the sequence of analysis. The cost-effective CyFlow MiniPOC produces rapid, reliable and accurate results that are fully comparable with those from highly expensive dual platform systems.

Comparison between three mini-sling surgical procedures and the traditional transobturator vaginal tape technique for female stress urinary incontinence

PubMed Central

LEANZA, V.; INTAGLIATA, E.; LEANZA, A.; FERLA, F.; LEANZA, G.; VECCHIO, R.

2014-01-01

Objectives To compare mini-sling and traditional tension-free operations for female stress urinary incontinence. Study design A systematic review of articles in the Literature published between 2002 and 2012, was conducted. A Pubmed search was performed. Primary outcomes were subjective and objective cure rates at 12 months comparing the three single-incision mini-slings techniques (TVT-Secur, MiniArc and Monarc systems) with the standard mid-urethral sling procedure TOT (Transobturator Vaginal Tape). Secondary outcomes included peri-operative (vaginal and/or bladder perforation, urine retention, urinary tract infection, bleeding, pain) and post-operative (mesh exposure, de novo urgency, and dyspareunia) complications. Results In term of objective cure rate at 12 month after surgery, it is evident that TOT at first, and MiniArc are the most effective procedures. The incidence of post-operative urgency and UTI was lower in TOT technique, while vaginal perforation was described in equal frequency both in TOT and in MiniArc procedures. The advantages of the three above described mini-invasive techniques seem to consist into lower cases of urinary retention, pain and bleeding. Furthermore, bladder perforation and bleeding are not described in the Literature for TVT-Secur and Monarc systems. Conclusions Some single-incision slings look promising and as effective as conventional sub-urethral slings at short term evaluation. However, at this moment a clear statement in favor of the widespread use of single-incision slings cannot be made. More studies must define the efficacy of these techniques. PMID:24841685

Reliability, validity and minimal detectable change of the Mini-BESTest in Greek participants with chronic stroke.

PubMed

Lampropoulou, Sofia I; Billis, Evdokia; Gedikoglou, Ingrid A; Michailidou, Christina; Nowicky, Alexander V; Skrinou, Dimitra; Michailidi, Fotini; Chandrinou, Danae; Meligkoni, Margarita

2018-02-23

This study aimed to investigate the psychometric characteristics of reliability, validity and ability to detect change of a newly developed balance assessment tool, the Mini-BESTest, in Greek patients with stroke. A prospective, observational design study with test-retest measures was conducted. A convenience sample of 21 Greek patients with chronic stroke (14 male, 7 female; age of 63 ± 16 years) was recruited. Two independent examiners administered the scale, for the inter-rater reliability, twice within 10 days for the test-retest reliability. Bland Altman Analysis for repeated measures assessed the absolute reliability and the Standard Error of Measurement (SEM) and the Minimum Detectable Change at 95% confidence interval (MDC 95% ) were established. The Greek Mini-BESTest (Mini-BESTest GR ) was correlated with the Greek Berg Balance Scale (BBS GR ) for assessing the concurrent validity and with the Timed Up and Go (TUG), the Functional Reach Test (FRT) and the Greek Falls Efficacy Scale-International (FES-I GR ) for the convergent validity. The Mini-BESTestGR demonstrated excellent inter-rater reliability (ICC (95%CI) = 0.997 (0.995-0.999, SEM = 0.46) with the scores of two raters within the limits of agreement (mean dif  = -0.143 ± 0.727, p > 0.05) and test-retest reliability (ICC (95%CI) = 0.966 (0.926-0.988), SEM = 1.53). Additionally, the Mini-BESTest GR yielded very strong to moderate correlations with BBS GR (r = 0.924, p < 0.001), TUG (r = -0.823, p < 0.001), FES-I GR (r = -0.734, p < 0.001) and FRT (r = 0.689, p < 0.001). MDC 95 was 4.25 points. The exceptionally high reliability and the equally good validity of the Mini-BESTest GR , strongly support its utility in Greek people with chronic stroke. Its ability to identify clinically meaningful changes and falls risk need further investigation.

Mini Review: Mode of Action of Mosquito Repellents

DTIC Science & Technology

2013-01-01

Mini review: Mode of action of mosquito repellents Joseph C. Dickens ⇑, Jonathan D. Bohbot United States Department of Agriculture, Agricultural...Modulation a b s t r a c t The mode of action of mosquito repellents remains a controversial topic. However, electrophysiological studies and molecular...annoyance that can disrupt outdoor activities. The use of repellents decreases contacts between mosquitoes and their hosts, and may even lower the rate of

Neutrino Nucleon Elastic Scattering in MiniBooNE

NASA Astrophysics Data System (ADS)

Cox, D. Christopher

2007-12-01

Neutrino nucleon elastic scattering νN→νN is a fundamental process of the weak interaction, and can be used to study the structure of the nucleon. This is the third largest scattering process in MiniBooNE comprising ˜15% of all neutrino interactions. Analysis of this sample has yielded a neutral current elastic differential cross section as a function of Q2 that agrees within errors to model predictions.

An in vitro investigation of peak insertion torque values of six commercially available mini-implants.

PubMed

Whang, C Z Y; Bister, D; Sherriff, M

2011-12-01

This study compared peak insertion torque values of six commercially available self-drilling mini-implants [Mini Spider® screw (1.5 × 8 mm), Infinitas® (1.5 × 9 mm), Vector TAS® (1.4 × 8 mm), Dual Top® (1.6 × 8 mm), Tomas Pin® (1.6 × 8 mm), and Ortho-Easy® (1.7 × 6, 8, and 10 mm)]. Twenty implants each were drilled into acrylic rods at a speed of 8 rpm using a motorized torque measurement stand, and the values were recorded in Newton centimetres (Ncm). A further 20 Ortho-Easy® implants with a length of 6 and 10 mm were tested at 8 rpm; 20 implants of 6 mm length were also tested at 4 rpm. Kaplan-Meier estimates of the peak torque values were compared using the log-rank test with multiple comparisons evaluated by Sidak's test. There were significant differences in the maximum torque values for different mini-implants with the same length. The Mini Spider® screw and Infinitas® showed the lowest average torque values (6.5 and 12.4 Ncm) compared with Vector TAS®, Dual ToP®, Tomas Pin®, and Ortho-Easy® (30.9, 29.4, 25.4, and 24.8 Ncm, respectively). There was no correlation between the diameter of the implants and torque values. The Tomas Pin® showed the largest standard deviation (7.7 Ncm) and the Dual Top® implant the smallest (0.6 Ncm). Different insertion speeds did not result in significant differences in peak torque values but the 6 mm mini-implants showed significantly higher torque values than the 8 and 10 mm implants. Using a 'torque limiting' screwdriver or pre-drilling cortical bone to reduce insertion, torque appears justified for some of the tested implants.

Comparison of the Mini-Balance Evaluations Systems Test with the Berg Balance Scale in relationship to walking speed and motor recovery post stroke

PubMed Central

Madhavan, Sangeetha; Bishnoi, Alka

2017-01-01

Background The Mini-BESTest is a recently developed balance assessment tool that incorporates challenging dynamic balance tasks. Few studies have compared the psychometric properties of the Mini-BESTest to the commonly used Berg Balance Scale (BBS). However, the utility of these scales in relationship to post stroke walking speeds has not been explored. Objectives The purpose of this study was to compare the sensitivity and specificity of the Mini-BESTest and BBS to evaluate walking speeds in individuals with stroke. Design A retrospective exploratory design. Methods Forty-one individuals with chronic stroke were evaluated with the Mini-BESTest, BBS, and 10-meter self-selected walk test (10MWT). Based on their self-selected gait speeds (below or above 0.8 m/s), participants were classified as slow and fast walkers. Results Significant linear correlations were observed between the Mini-BESTest vs. BBS (r = 0.72, p ≤ 0.001), Mini-BESTest vs. 10MWT (r = 0.58, p ≤ 0.001), and BBS vs. 10MWT (r = 0.30, p = 0.05). Independent t-tests comparing the balance scores for the slow and fast walkers revealed significant group differences for the Mini-BESTest (p =0.003), but not for the BBS (p = 0.09). The Mini-BESTest demonstrated higher sensitivity (93%) and specificity (64%) compared to the BBS (sensitivity 81%, specificity 56%) for discriminating participants into slow and fast walkers. No significant results were observed with the FMLE-M scores. Conclusions The Mini-BESTest has a greater discriminative ability than the BBS to categorize individuals with stroke into slow and fast walkers. PMID:28826325

Fast-flowering mini-maize: seed to seed in 60 days

USDA-ARS?s Scientific Manuscript database

Two lines of Zea mays were developed as a short-generation model for maize. The Fast-Flowering Mini-Maize (FFMM) lines A and B are robust inbred lines with a significantly shorter generation time, much smaller stature, and better greenhouse adaptation than traditional maize varieties. Five generatio...

Aptamers and apple pies: a mini-review of PSMA aptamers and lessons from Donald S. Coffey

PubMed Central

Lupold, Shawn E

2018-01-01

This mini-review article is part of a special issue dedicated to Donald S. Coffey, a pioneer translational research scientist, exemplary mentor, and leader in urologic and urologic oncology research. This article first briefly reflects on life and scientific lessons from Don Coffey. It then reviews the development of two prostate cancer targeting RNA aptamers, xPSM-A9 and xPSM-A10, through in vitro selection for aptamers that bind to the extracellular domain of the Prostate Specific Membrane Antigen (PSMA). These 2’-fluorpyrimidine RNA aptamers selectively bind PSMA on the surface of prostate cancer cells, inhibit PSMA glutamate carboxypeptidase activity, and internalize into PSMA-expressing cancer cells. The truncation of both aptamers, through experimentation as well as logical design, has produced smaller isoforms including A10-3, A10-3.2, A9g and A9L. The larger aptamer isoforms xPSM-A9 and xPSM-A10 are limited to production by in vitro transcription and polyacrylamide gel purification, while smaller isoforms can be generated by chemically synthesis. A series of aptamer conjugates have been developed through chemical crosslinking, complementary annealing strategies, or a combination of both, for the targeting of experimental therapeutics to and into prostate cancer cells. The resulting aptamer conjugates, including nanoparticles and siRNA conjugates, selectively target PSMA-positive prostate cancer cells and xenograft tumors, and demonstrate potent cytotoxic and tumoricidal activity. These experimental therapeutic agents provide a platform for realizing and optimizing the potential of tumor-selective targeting and drug delivery. PMID:29666835

Immediately loaded mini dental implants as overdenture retainers: 1-Year cohort study of implant stability and peri-implant marginal bone level.

PubMed

Šćepanović, Miodrag; Todorović, Aleksandar; Marković, Aleksa; Patrnogić, Vesna; Miličić, Biljana; Moufti, Adel M; Mišić, Tijana

2015-05-01

This 1-year cohort study investigated stability and peri-implant marginal bone level of immediately loaded mini dental implants used to retain overdentures. Each of 30 edentulous patients received 4 mini dental implants (1.8 mm × 13 mm) in the interforaminal mandibular region. The implants were immediately loaded with pre-made overdentures. Outcome measures included implant stability and bone resorption. Implant stability was measured using the Periotest Classic(®) device immediately after placement and on the 3rd and 6th weeks and the 4th, 6th and 12th months postoperatively. The peri-implant marginal bone level (PIBL) was evaluated at the implant's mesial and distal sides from the polished platform to the marginal crest. Radiographs were taken using a tailored film holder to reproducibly position the X-ray tube at the 6th week, 4th and 12th months postoperatively. The primary stability (Periotest value, PTV) measured -0.27 ± 3.41 on a scale of -8 to + 50 (lower PTV reflects higher stability). The secondary stability decreased significantly until week 6 (mean PTV = 7.61 ± 7.05) then increased significantly reaching (PTV = 6.17 ± 6.15) at 12 months. The mean PIBL measured -0.40 mm after 1 year of functional loading, with no statistically significant differences at the various follow-ups (p = 0.218). Mini dental implants placed into the interforaminal region could achieve a favorable primary stability for immediate loading. The follow-up Periotest values fluctuated, apparently reflecting the dynamics of bone remodeling, with the implants remaining clinically stable (98.3%) after 1 year of function. The 1-year bone resorption around immediately loaded MDIs is within the clinically acceptable range for standard implants. Copyright © 2014 Elsevier GmbH. All rights reserved.

Mini Versus Standard Percutaneous Nephrolithotomy: The Impact of Sheath Size on Intrarenal Pelvic Pressure and Infectious Complications in a Porcine Model.

PubMed

Loftus, Christopher J; Hinck, Bryan; Makovey, Iryna; Sivalingam, Sri; Monga, Manoj

2018-04-01

To determine how sheath and endoscope size affect intrarenal pelvic pressures and risk of postoperative infectious complications comparing "Mini" vs "Standard" percutaneous nephrolithotomy (PCNL). Uropathogenic Escherichia coli were grown and 10 9 of them were instilled into the porcine renal pelvis through retrograde access for 1 hour. Percutaneous access utilized a 14/16F 20 cm ureteral access sheath for the Mini arm and a 30F sheath for the Standard arm. Nephroscopy was simulated utilizing either an 8/9.8F semirigid ureteroscope or 26F nephroscope for 1 hour while intrarenal pelvic pressure was continuously monitored. Blood and tissue cultures of kidney, liver, and spleen biopsies were plated and incubated and positive cultures were confirmed with polymerase chain reaction. Intrapelvic pressures were higher in the Mini group, 18.76 ± 5.82 mm Hg vs 13.56 ± 5.82 mm Hg (p < 0.0001). Time spent above 30 mm Hg was greater in the Mini arm, 117.0 seconds vs 66.1 seconds (p = 0.0452). All pigs had positive kidney tissue cultures whereas spleen cultures were positive in 100% and 60% of pigs in the Mini and Standard arms, respectively (p = 0.0253); 90% and 30% had positive liver tissue culture in the Mini and Standard arms, respectively (p = 0.0062). Blood cultures were positive in 30% of pigs in the Mini arm compared with none in the Standard arm (p = 0.0603). Mini-PCNL was associated with higher intrarenal pressures and higher risk of end organ bacterial seeding in the setting of an infected collecting system. This suggests a higher potential for infectious complications in a clinical setting.

The Crystal Structure of a Maxi/Mini-Ferritin Chimera Reveals Guiding Principles for the Assembly of Protein Cages

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cornell, Thomas A.; Srivastava, Yogesh; Jauch, Ralf

Cage proteins assemble into nanoscale structures with large central cavities. They play roles, including those as virus capsids and chaperones, and have been applied to drug delivery and nanomaterials. Furthermore, protein cages have been used as model systems to understand and design protein quaternary structure. Ferritins are ubiquitous protein cages that manage iron homeostasis and oxidative damage. Two ferritin subfamilies have strongly similar tertiary structure yet distinct quaternary structure: maxi-ferritins normally assemble into 24-meric, octahedral cages with C-terminal E-helices centered around 4-fold symmetry axes, and mini-ferritins are 12-meric, tetrahedral cages with 3-fold axes defined by C-termini lacking E-domains. To understandmore » the role E-domains play in ferritin quaternary structure, we previously designed a chimera of a maxi-ferritin E-domain fused to the C-terminus of a mini-ferritin. The chimera is a 12-mer cage midway in size between those of the maxi- and mini-ferritin. The research described herein sets out to understand (a) whether the increase in size over a typical mini-ferritin is due to a frozen state where the E-domain is flipped out of the cage and (b) whether the symmetrical preference of the E-domain in the maxi-ferritin (4-fold axis) overrules the C-terminal preference in the mini-ferritin (3-fold axis). With a 1.99 Å resolution crystal structure, we determined that the chimera assembles into a tetrahedral cage that can be nearly superimposed with the parent mini-ferritin, and that the E-domains are flipped external to the cage at the 3-fold symmetry axes.« less

A Mini-Electrochemical System with Integrated Micropipet Tip and Pencil Graphite Electrode for Measuring Cytotoxicity.

PubMed

Wu, Dong-Mei; Guo, Xiao-Ling; Wang, Qian; Li, Jin-Lian; Cui, Ji-Wen; Zhou, Shi; Hao, Su-E

2017-01-01

A novel mini-electrochemical system has been developed for evaluating cytotoxicity of anticancer drugs based on trace cell samples. The mini-electrochemical system was integrated by using pencil graphite modified with threonine as working electrode, an Ag/AgCl reference electrode and a micropipet tip as electrochemical cell. The mini-electrochemical system dramatically reduces sample volumes from 500 μL in a traditional electrochemical system to 10 μL, and exhibits excellent electrocatalytic activity toward oxidation of purine from MCF-7 cells due to increased sensitivity provided by threonine. Moreover, the relationship between peak current and the cell concentration in the range from 3.0 × l0 3 to 7.0 × l0 6 cells/mL was studied, and a nonlinear exponential relationship between them was established over a wide concentration range. In evaluating the effect of anticancer drugs on cell viability, the results of drug cytotoxicity test based on cyclophosphamide were in close agreement with classical 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assays. The proposed device is so simple, cheap, and easy to operate that it could be applied to single-use applications. The mini-electrochemical system proved to be a useful tool and can be applied to electrochemical studies of cancer cells as well as other biological samples such as proteins and DNA.

Percutaneous carpal tunnel release compared with mini-open release using ultrasonographic guidance for both techniques.

PubMed

Nakamichi, Ken-ichi; Tachibana, Shintaro; Yamamoto, Seizo; Ida, Masayoshi

2010-03-01

To compare the outcomes of percutaneous carpal tunnel release (PCTR) and mini-open carpal tunnel release (mini-OCTR) using ultrasonographic guidance for both techniques. We included 74 hands of 65 women with idiopathic carpal tunnel syndrome (age, 52-71 y; mean, 58 y). Thirty-five hands of 29 women had the PCTR (release with a device consisting of an angled blade, guide, and holder, along a line midway between the median nerve and ulnar artery (safe line) under ultrasonography (incision, 4 mm), and 39 hands of 36 women had the mini-OCTR (release along the safe line, distally under direct vision (incision, 1-1.5 cm) and proximally under ultrasonography, using a device consisting of a basket punch and outer tube. Assessments at 3, 6, 13, 26, 52, and 104 weeks showed no significant differences in neurologic recovery between the groups (p > .05). The PCTR group had significantly less pain, greater grip and key-pinch strengths, and better satisfaction scores at 3 and 6 weeks (p < .05), and less scar sensitivity at 3, 6, and 13 weeks (p < .05). There were no complications. The PCTR provides the same neurologic recovery as does the mini-OCTR. The former leads to less postoperative morbidity and earlier functional return and achievement of satisfaction. Therapeutic III. Copyright 2010. Published by Elsevier Inc.

PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina

PubMed Central

Hickmott, Jack W; Chen, Chih-yu; Arenillas, David J; Korecki, Andrea J; Lam, Siu Ling; Molday, Laurie L; Bonaguro, Russell J; Zhou, Michelle; Chou, Alice Y; Mathelier, Anthony; Boye, Sanford L; Hauswirth, William W; Molday, Robert S; Wasserman, Wyeth W; Simpson, Elizabeth M

2016-01-01

Current gene therapies predominantly use small, strong, and readily available ubiquitous promoters. However, as the field matures, the availability of small, cell-specific promoters would be greatly beneficial. Here we design seven small promoters from the human paired box 6 (PAX6) gene and test them in the adult mouse retina using recombinant adeno-associated virus. We chose the retina due to previous successes in gene therapy for blindness, and the PAX6 gene since it is: well studied; known to be driven by discrete regulatory regions; expressed in therapeutically interesting retinal cell types; and mutated in the vision-loss disorder aniridia, which is in need of improved therapy. At the PAX6 locus, 31 regulatory regions were bioinformatically predicted, and nine regulatory regions were constructed into seven MiniPromoters. Driving Emerald GFP, these MiniPromoters were packaged into recombinant adeno-associated virus, and injected intravitreally into postnatal day 14 mice. Four MiniPromoters drove consistent retinal expression in the adult mouse, driving expression in combinations of cell-types that endogenously express Pax6: ganglion, amacrine, horizontal, and Müller glia. Two PAX6-MiniPromoters drive expression in three of the four cell types that express PAX6 in the adult mouse retina. Combined, they capture all four cell types, making them potential tools for research, and PAX6-gene therapy for aniridia. PMID:27556059

PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina.

PubMed

Hickmott, Jack W; Chen, Chih-Yu; Arenillas, David J; Korecki, Andrea J; Lam, Siu Ling; Molday, Laurie L; Bonaguro, Russell J; Zhou, Michelle; Chou, Alice Y; Mathelier, Anthony; Boye, Sanford L; Hauswirth, William W; Molday, Robert S; Wasserman, Wyeth W; Simpson, Elizabeth M

2016-01-01

Current gene therapies predominantly use small, strong, and readily available ubiquitous promoters. However, as the field matures, the availability of small, cell-specific promoters would be greatly beneficial. Here we design seven small promoters from the human paired box 6 (PAX6) gene and test them in the adult mouse retina using recombinant adeno-associated virus. We chose the retina due to previous successes in gene therapy for blindness, and the PAX6 gene since it is: well studied; known to be driven by discrete regulatory regions; expressed in therapeutically interesting retinal cell types; and mutated in the vision-loss disorder aniridia, which is in need of improved therapy. At the PAX6 locus, 31 regulatory regions were bioinformatically predicted, and nine regulatory regions were constructed into seven MiniPromoters. Driving Emerald GFP, these MiniPromoters were packaged into recombinant adeno-associated virus, and injected intravitreally into postnatal day 14 mice. Four MiniPromoters drove consistent retinal expression in the adult mouse, driving expression in combinations of cell-types that endogenously express Pax6: ganglion, amacrine, horizontal, and Müller glia. Two PAX6-MiniPromoters drive expression in three of the four cell types that express PAX6 in the adult mouse retina. Combined, they capture all four cell types, making them potential tools for research, and PAX6-gene therapy for aniridia.

The ASTRI mini-array software system (MASS) implementation: a proposal for the Cherenkov Telescope Array

NASA Astrophysics Data System (ADS)

Tanci, Claudio; Tosti, Gino; Conforti, Vito; Schwarz, Joseph; Antolini, Elisa; Antonelli, L. A.; Bulgarelli, Andrea; Bigongiari, Ciro; Bruno, Pietro; Canestrari, Rodolfo; Capalbi, Milvia; Cascone, Enrico; Catalano, Osvaldo; Di Paola, Andrea; Di Pierro, Federico; Fioretti, Valentina; Gallozzi, Stefano; Gardiol, Daniele; Gianotti, Fulvio; Giro, Enrico; Grillo, Alessandro; La Palombara, Nicola; Leto, Giuseppe; Lombardi, Saverio; Maccarone, Maria C.; Pareschi, Giovanni; Russo, Federico; Sangiorgi, Pierluca; Scuderi, Salvo; Stringhetti, Luca; Testa, Vincenzo; Trifoglio, Massimo; Vercellone, Stefano; Zoli, Andrea

2016-08-01

The ASTRI mini-array, composed of nine small-size dual mirror (SST-2M) telescopes, has been proposed to be installed at the southern site of the Cherenkov Telescope Array (CTA), as a set of preproduction units of the CTA observatory. The ASTRI mini-array is a collaborative and international effort carried out by Italy, Brazil and South Africa and led by the Italian National Institute of Astrophysics, INAF. We present the main features of the current implementation of the Mini-Array Software System (MASS) now in use for the activities of the ASTRI SST-2M telescope prototype located at the INAF observing station on Mt. Etna, Italy and the characteristics that make it a prototype for the CTA control software system. CTA Data Management (CTADATA) and CTA Array Control and Data Acquisition (CTA-ACTL) requirements and guidelines as well as the ASTRI use cases were considered in the MASS design, most of its features are derived from the Atacama Large Millimeter/sub-millimeter Array Control software. The MASS will provide a set of tools to manage all onsite operations of the ASTRI mini-array in order to perform the observations specified in the short term schedule (including monitoring and controlling all the hardware components of each telescope and calibration device), to analyze the acquired data online and to store/retrieve all the data products to/from the onsite repository.

Design of mini-multi-gas monitoring system based on IR absorption

NASA Astrophysics Data System (ADS)

Tan, Qiu-lin; Zhang, Wen-dong; Xue, Chen-yang; Xiong, Ji-jun; Ma, You-chun; Wen, Fen

2008-07-01

In this paper, a novel non-dispersive infrared ray (IR) gas detection system is described. Conventional devices typically include several primary components: a broadband source (usually an incandescent filament), a rotating chopper shutter, a narrow-band filter, a sample tube and a detector. But we mainly use the mini-multi-channel detector, electrical modulation means and mini-gas-cell structure. To solve the problems of gas accidents in coal mines, and for family safety that results from using gas, this new IR detection system with integration, miniaturization and non-moving parts has been developed. It is based on the principle that certain gases absorb infrared radiation at specific (and often unique) wavelengths. The infrared detection optics principle used in developing this system is mainly analyzed. The idea of multi-gas detection is introduced and guided through the analysis of the single-gas detection. Through researching the design of cell structure, a cell with integration and miniaturization has been devised. By taking a single-chip microcomputer (SCM) as intelligence handling, the functional block diagram of a gas detection system is designed with the analyzing and devising of its hardware and software system. The way of data transmission on a controller area network (CAN) bus and wireless data transmission mode is explained. This system has reached the technology requirement of lower power consumption, mini-volume, wide measure range, and is able to realize multi-gas detection.

A Mini Axial and a Permanent Maglev Radial Heart Pump§

PubMed Central

Qian, Kun-Xi; Ru, Wei-Min; Wang, Hao; Jing, Teng

2007-01-01

The implantability and durability have been for decades the focus of artificial heart R&D. A mini axial and a maglev radial pump have been developed to meet with such requirements. The mini axial pump weighing 27g (incl.5g rotor) has an outer diameter of 21mm and a length of 10mm in its largest point, but can produce a maximal blood flow of 6l/min with 50mmHg pressure increase. Therefore, it is suitable for the patients of 40-60kg body weight. For other patients of 60-80kg or 80-100kg body weight, the mini axial pumps of 23mm and 25mm outer diameter had been developed before, these devices were acknowledged to be the world smallest LVADs by Guinness World Record Center in 2004. The permanent maglev radial pump weighing 150g is a shaft-less centrifugal pump with permanent magnetic bearings developed by the author. It needs no second coil for suspension of the rotor except the motor coil, different from all other maglev pumps developed in USA, Japan, European, etc. Thus no detecting and controlling systems as well as no additional power supply for maglev are necessary. The pump can produce a blood flow up to as large as 10l/min against 100mmHg pressure. An implantable and durable blood pump will be a viable alternative to natural donor heart for transplantation. PMID:19662120

Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review.

PubMed

Tomas, Cara; Newton, Julia

2018-04-17

Chronic fatigue syndrome (CFS), commonly known as myalgic encephalomyelitis (ME), is a debilitating disease of unknown etiology. CFS/ME is a heterogeneous disease associated with a myriad of symptoms but with severe, prolonged fatigue as the core symptom associated with the disease. There are currently no known biomarkers for the disease, largely due to the lack of knowledge surrounding the eitopathogenesis of CFS/ME. Numerous studies have been conducted in an attempt to identify potential biomarkers for the disease. This mini-review offers a brief summary of current research into the identification of metabolic abnormalities in CFS/ME which may represent potential biomarkers for the disease. The progress of research into key areas including immune dysregulation, mitochondrial dysfunction, 5'-adenosine monophosphate-activated protein kinase activation, skeletal muscle cell acidosis, and metabolomics are presented here. Studies outlined in this mini-review show many potential causes for the pathogenesis of CFS/ME and identify many potential metabolic biomarkers for the disease from the aforementioned research areas. The future of CFS/ME research should focus on building on the potential biomarkers for the disease using multi-disciplinary techniques at multiple research sites in order to produce robust data sets. Whether the metabolic changes identified in this mini-review occur as a cause or a consequence of the disease must also be established. © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

Mini-Laparotomy for Superior Mesenteric Artery Aneurysm Due to Takayasu's Arteritis.

PubMed

Matsumoto, Takatsugu; Ishizuka, Mitsuru; Iso, Yukihiro; Kita, Junji; Kubota, Keiichi

2015-04-01

Superior mesenteric artery aneurysm (SMAA) is reported to be the third-most common type of visceral aneurysm (VA), accounting for 5% of all VAs. The etiology of SMAA is commonly thought to be infection, and it usually exists in the proximal part of the superior mesenteric artery, which is suitable for endovascular treatment. We herein report an extremely rare case of the distal part of SMAA caused by Takayasu's arteritis (TA), which was successfully resected using a mini-laparotomy method without impairing the intestinal blood supply. A 51-year-old woman was admitted to our hospital with sustained fever and lower back pain. Physical examination showed that she had a discrepancies in blood pressure between both arms. Contrast-enhanced whole-body computed tomography showed stenosis of the thoracic aorta and an aneurysm located in the distal part of the superior mesenteric artery. The diameter of the aneurysm was 4.5 cm. The aneurysm was resected via 4-cm mini-laparotomy, and the vascularity of the intestine was successfully preserved. The postoperative course was uneventful, and the patient was diagnosed as having TA based on both clinical and pathologic findings. Additional corticosteroid therapy was started to treat the arteritis, and at 3-month follow-up she was without critical incidents. Mini-laparotomy is a safe and less-invasive approach to treat SMAA, especially when the lesion is located in the distal part of the artery.

No WIMP mini-spikes in dwarf spheroidal galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wanders, Mark; Bertone, Gianfranco; Weniger, Christoph

The formation of black holes inevitably affects the distribution of dark and baryonic matter in their vicinity, leading to an enhancement of the dark matter density, called spike, and if dark matter is made of WIMPs, to a strong enhancement of the dark matter annihilation rate. Spikes at the center of galaxies like the Milky Way are efficiently disrupted by baryonic processes, but mini-spikes can form and survive undisturbed at the center of dwarf spheroidal galaxies. We show that Fermi LAT satellite data allow to set very stringent limits on the existence of mini-spikes in dwarf galaxies: for thermal WIMPsmore » with mass between 100 GeV and 1 TeV, we obtain a maximum black hole mass between 100 and 1000 M{sub ⊙}, ruling out black holes masses extrapolated from the M-σ relationship in a large region of the parameter space. We also performed Monte Carlo simulations of merger histories of black holes in dwarf spheroidals in a scenario where black holes form from the direct collapse of primordial gas in early halos, and found that this specific formation scenario is incompatible at the 84% CL with dark matter being in the form of thermal WIMPs.« less

An anthropological approach to teach and evaluate cultural competence in medical students - the application of mini-ethnography in medical history taking.

PubMed

Hsieh, Jyh-Gang; Hsu, Mutsu; Wang, Ying-Wei

2016-01-01

Purpose To use mini-ethnographies narrating patient illness to improve the cultural competence of the medical students. Methods Between September 2013 and June 2015, all sixth-year medical students doing their internship at a medical center in eastern Taiwan were trained to write mini-ethnographies for one of the patients in their care. The mini-ethnographies were analyzed by authors with focus on the various aspects of cultural sensitivity and a holistic care approach. Results Ninety-one students handed in mini-ethnographies, of whom 56 were male (61.5%) and 35 were female (38.5%). From the mini-ethnographies, three core aspects were derived: 1) the explanatory models and perceptions of illness, 2) culture and health care, and 3) society, resources, and health care. Based on the qualities of each aspect, nine secondary nodes were classified: expectations and attitude about illness/treatment, perceptions about their own prognosis in particular, knowledge and feelings regarding illness, cause of illness, choice of treatment method (including traditional medical treatments), prejudice and discrimination, influences of traditional culture and language, social support and resources, and inequality in health care. Conclusions Mini-ethnography is an effective teaching method that can help students to develop cultural competence. It also serves as an effective instrument to assess the cultural competence of medical students.

Transportation Consumer Education for Adults: Mini-Units and Learning Activities.

ERIC Educational Resources Information Center

Finn, Peter; And Others

One of a series of eleven curriculum manuals which cover the four transportation topics of public transportation, transportation and the environment, transportation safety, and bicycles for elementary, secondary, and adult levels, this manual covers all four topics at the adult level. Materials in four chapters comprising seventeen mini-units…

Articular Exposure with the Swashbuckler versus a Mini-Swashbuckler Approach

DTIC Science & Technology

2012-01-01

autogenous bone grafting.1–4,15–16 Modern minimally invasive plating techniques which utilise indirect reduction of the metadiaphysis, even in the presence of...room conditions. All approaches were then performed by the senior author (J.R.H.), a fellowship- trained orthopaedic traumatologist. A Mini-swashbuckler

Tools for the IDL widget set within the X-windows environment

NASA Technical Reports Server (NTRS)

Turgeon, B.; Aston, A.

1992-01-01

New tools using the IDL widget set are presented. In particular, a utility allowing the easy creation and update of slide presentations, XSlideManager, is explained in detail and examples of its application are shown. In addition to XSlideManager, other mini-utilities are discussed. These various pieces of software follow the philosophy of the X-Windows distribution system and are made available to anyone within the Internet network. Acquisition procedures through anonymous ftp are clearly explained.

Selective Photocatalytic Disinfection by Coupling StrepMiniSog to the Antibody Catalyzed Water Oxidation Pathway

PubMed Central

2016-01-01

For several decades reactive oxygen species have been applied to water quality engineering and efficient disinfection strategies; however, these methods are limited by disinfection byproduct and catalyst-derived toxicity concerns which could be improved by selectively targeting contaminants of interest. Here we present a targeted photocatalytic system based on the fusion protein StrepMiniSOG that uses light within the visible spectrum to produce reactive oxygen species at a greater efficiency than current photosensitizers, allowing for shorter irradiation times from a fully biodegradable photocatalyst. The StrepMiniSOG photodisinfection system is unable to cross cell membranes and like other consumed proteins, can be degraded by endogenous digestive enzymes in the human gut, thereby reducing the consumption risks typically associated with other disinfection agents. We demonstrate specific, multi-log removal of Listeria monocytogenes from a mixed population of bacteria, establishing the StrepMiniSOG disinfection system as a valuable tool for targeted pathogen removal, while maintaining existing microbial biodiversity. PMID:27617441

Selective Photocatalytic Disinfection by Coupling StrepMiniSog to the Antibody Catalyzed Water Oxidation Pathway.

PubMed

Wurtzler, Elizabeth M; Wendell, David

2016-01-01

For several decades reactive oxygen species have been applied to water quality engineering and efficient disinfection strategies; however, these methods are limited by disinfection byproduct and catalyst-derived toxicity concerns which could be improved by selectively targeting contaminants of interest. Here we present a targeted photocatalytic system based on the fusion protein StrepMiniSOG that uses light within the visible spectrum to produce reactive oxygen species at a greater efficiency than current photosensitizers, allowing for shorter irradiation times from a fully biodegradable photocatalyst. The StrepMiniSOG photodisinfection system is unable to cross cell membranes and like other consumed proteins, can be degraded by endogenous digestive enzymes in the human gut, thereby reducing the consumption risks typically associated with other disinfection agents. We demonstrate specific, multi-log removal of Listeria monocytogenes from a mixed population of bacteria, establishing the StrepMiniSOG disinfection system as a valuable tool for targeted pathogen removal, while maintaining existing microbial biodiversity.

The Interdisciplinary Mini-Course: Instructional Development for Language Classes.

ERIC Educational Resources Information Center

Wilkins, Wynona H.; Boswau, Herbert H.

Curricula for interdisciplinary courses that enable second language classes to employ the arts are proposed. At the University of North Dakota, mini-courses provide one-semester credit and are given for 2 hours 1 day a week over a period of 8 weeks. Some of the courses are cross-listed with other departments. Two of these courses, Joan of Arc and…

Introduction of vincristine mini-bags and an assessment of the subsequent risk of extravasation.

PubMed

Nurgat, Z A; Smythe, M; Al-Jedai, A; Ewing, S; Rasheed, W; Belgaumi, A; Ahmed, S O; Ashour, M; Al Agil, A; Siddiqui, K; Aljurf, M

2015-10-01

Numerous international organisations have advocated the preparation of vincristine in small volume intravenous bags in order to eliminate inadvertent intrathecal administration. However, the risk of extravasation is a significant deterrent, and adoption of this practice has been variable and only hesitantly accepted in the clinical setting. We carried out a study with the aims of establishing the incidence of reported extravasation of vincristine administration to paediatric and adult patients in mini-bags; here we describe motivating factors and barriers faced by clinical staff. The secondary aim was to support the need for change and implementation of the international recommendations. Chemotherapy-certified nurses completed a survey spanning August 2009 to August 2011, to ascertain the incidence of extravasation associated with the administration of vincristine in mini-bags. This period captured 421 occasions of vincristine administration in 25-ml or 50-ml mini-bags (in 0.9% sodium chloride). The median age of patients was 13 years (range 2.5 months to 99 years). Vincristine was administered through peripheral lines (26.4%), portacath (52.0%), PICC line (15.9%) and Hickman line (5.7%). The majority of infusions were over at least 10 minutes (50.1%). There were no cases of extravasation reported. The administration of vincristine in small volume intravenous bags was safe, practical, and feasible in all patient groups. The successful implementation of the international recommendations for vincristine administration in mini-bags to eliminate potential inadvertent intrathecal administration was dependent on stakeholder buy-in. © The Author(s) 2014.

Experimental investigation on the miniature mixed refrigerant cooler driven by a mini-compressor

NASA Astrophysics Data System (ADS)

Chen, Gaofei; Gong, Maoqiong; Wu, Yinong

2018-05-01

Three miniature Joule-Thomson cryogenic coolers and a testing set up were built to investigate the cooling performance in this work. Shell-and-tube heat exchanger and plate fin heat exchangers with rectangular micro channels were designed to achieve high specific surface area. The main processing technology of micro mixed refrigerant cooler (MMRC) was described. The design and fabrication processing of the plate fin heat exchangers were also described. The new developed micro plate-fin type heat exchanger shows high compactness with the specific heat surface larger than 1.0x104 m2/m3. The results of experimental investigations on miniature mixed refrigerant J-T cryogenic coolers driven by a Mini-Compressor were discussed. The performance evaluation and comparison of the three coolers was made to find out the features for each type of cooler. Expressions of refrigeration coefficient and exergy efficiency were pointed out. No-load temperature of about 112 K, and the cooling power of 4.0W at 118K with the input power of 120W is achieved. The exergy efficiency of the SJTC is 5.14%.

Battery-Powered Field Filtration Assembly Using an Inexpensive Mini-Compressor.

ERIC Educational Resources Information Center

Corbett, Robert G.; Quick, Thomas J.

1986-01-01

Suggests how modifications on a mini-compressor can result in a low-cost vacuum filtration system for use with suspended sediments in the field or laboratory. Explains and illustrates the changes needed to make the apparatus efficient and servicable for providing data for mass balance, geochemical exploration, and environmental studies. (ML)

Lunar metallic particle ("mini-moon"): An interpretation

USGS Publications Warehouse

McKay, D.S.; Carter, J.L.; Greenwood, W.R.

1971-01-01

A troilite-rich nickel-iron particle ("mini-moon") recovered from the moon may be a mound detached from a sphere of silicate glass. Erosion and pitting of the particle may have been caused by passage through a cloud of hot gas and particulate matter formed by meteorite impact on the lunar surface. This explanation is in contrast to the theory that the particle was meteoritically derived molten material that was furrowed during solidification after lunar impact, subsequently pitted by high-velocity particles, and then abraded and polished by drifting dust while on the lunar surface.

MD-miniRNA could be a more accurate biomarker for prostate cancer screening compared with serum prostate-specific antigen level.

PubMed

Xue, Dong; Zhou, Cui-Xing; Shi, Yun-Bo; Lu, Hao; He, Xiao-Zhou

2015-05-01

Prostate cancer and prostatic hyperplasia detection remains a great challenge, lacking of effective non-invasive and specific diagnostic biomarkers. In the current study, we aimed to identify the relative expression of plasma MD-miniRNA and its diagnostic performance in differentiating prostate cancer and prostatic hyperplasia patients from healthy controls, compared with serum prostate-specific antigen (PSA) level. All of the clinical participants (63 prostate cancer patients, 32 prostatic hyperplasia patients, and 50 healthy controls) were obtained from the Third Affiliated Hospital of Suzhou University in China between January 2013 and April 2014. Clinical characteristics were well matched. Plasma samples were extracted to test the relative expression of MD-miniRNA using the method of qRT-PCR. SPSS 22.0 statistical software package was used to analyze the data and GraphPad Prism 6.0 was used to generate the graphs. Relativity expression of plasma MD-miniRNA was significantly upregulated in prostate cancer, compared with prostatic hyperplasia patients and healthy controls. Serum PSA level revealed similar differences among these groups. MD-miniRNA presented a relatively high diagnostic accuracy with AUC of 0.86 (95 % CI 0.80-0.93) in differentiating prostate cancer patients from healthy controls. Simultaneously, MD-miniRNA was able to discriminate prostate cancer patients from prostatic hyperplasia controls with AUC of 0.79 (95 % CI 0.70-0.88). In addition, MD-miniRNA displayed a better diagnostic performance than PSA level. However, the panel of these two biomarkers revealed the best diagnostic performance, compared with either single biomarker. Results of this study showed that plasma MD-miniRNA could serve as a promising and noninvasive biomarker for diagnosing prostate cancer. Further large-scale studies are needed to confirm its clinical diagnosis accuracy.

The mini-exon genes of three Phytomonas isolates that differ in plant tissue tropism.

PubMed

Sturm, N R; Fernandes, O; Campbell, D A

1995-08-01

The tandem mini-exon gene repeat is an ideal diagnostic target for trypanosomatids because it includes sequences that are conserved absolutely coupled with regions of extreme variability. We have exploited these features and the polymerase chain reaction to differentiate Phytomonas strains isolated from phloem, fruit or latex of various host plants. While the transcribed regions are nearly identical, the intergenic sequences are variable in size and content (130-332 base pairs). The mini-exon genes of these phytomonads can therefore be distinguished from each other and from the corresponding genes in insect trypanosomes, with which they are oft confused.

GA3 and other signal regulators (MeJA and IAA) improve xanthumin biosynthesis in different manners in Xanthium strumarium L.

PubMed

Li, Changfu; Chen, Fangfang; Zhang, Yansheng

2014-08-25

Xanthanolides from Xanthium strumarium L. exhibit various pharmacological activities and these compounds are mainly produced in the glandular trichomes of aerial plant parts. The regulation of xanthanolide biosynthesis has never been reported in the literature. In this study, the effects of phytohormonal stimulation on xanthumin (a xanthanolide compound) biosynthesis, glandular trichomes and germacrene A synthase (GAS) gene expression in X. strumarium L. young leaves were investigated. The exogenous applications of methyl jasmonate (MeJA), indole-3-acetic acid (IAA), and gibberrellin A3 (GA3) at appropriate concentrations were all found to improve xanthumin biosynthesis, but in different ways. It was suggested that a higher gland density stimulated by MeJA (400 µM) or IAA (200 µM) treatment caused at least in part an improvement in xanthumin production, whereas GA3 (10 µM) led to an improvement by up-regulating xanthumin biosynthetic genes within gland cells, not by forming more glandular trichomes. Compared to the plants before the flowering stage, plants that had initiated flowering showed enhanced xanthumin biosynthesis, but no higher gland density, an effect was similar to that caused by exogenous GA3 treatment.

Humanities mini-course curricula for midcareer health professionals at the Penn State Milton S. Hershey Medical Center.

PubMed

Myers, Kimberly R; George, Daniel R

2012-08-01

The field of medical humanities has traditionally focused on medical students and, more recently, on premedical undergraduates. Comparatively little formal humanities pedagogy has been dedicated to midcareer health professionals. To address this lack, the Department of Humanities at the Pennsylvania State University College of Medicine and the Milton S. Hershey Medical Center designed eight annual humanities mini-courses for faculty and staff throughout the college and medical center.These mini-courses fell into four categories: reading, reflection, and discussion; creative expression; technology; and ethics. They were geared toward midcareer health professionals who were seeking new intellectual and creative stimulation and variety in daily routine. They also provided humanities faculty the opportunity to devote attention to topics that capitalize on their professional training and that interest them personally.Participants indicated a high degree of satisfaction with the mini-courses for four principal reasons: (1) learning the tools and methodologies of a new discipline or domain other than biomedicine, (2) using their minds and training in uncustomary ways, (3) forming new alliances with colleagues (which served to lessen the sense of professional isolation), and (4) enjoying a respite from the stressful flow of the workday. Humanities faculty facilitators provided more mixed responses but agreed that conducting the mini-courses had been a positive overall experience.Although this article provides a foundational framework for the development of a humanities mini-course series, the authors encourage others to replicate these curricula in other medical settings as an important step toward a robust pedagogy designed for midcareer health care professionals.

Finite element analysis of different loading conditions for implant-supported overdentures supported by conventional or mini implants.

PubMed

Solberg, K; Heinemann, F; Pellikaan, P; Keilig, L; Stark, H; Bourauel, C; Hasan, I

2017-05-01

The effect of implants' number on overdenture stability and stress distribution in edentulous mandible, implants and overdenture was numerically investigated for implant-supported overdentures. Three models were constructed. Overdentures were connected to implants by means of ball head abutments and rubber ring. In model 1, the overdenture was retained by two conventional implants; in model 2, by four conventional implants; and in model 3, by five mini implants. The overdenture was subjected to a symmetrical load at an angle of 20 degrees to the overdenture at the canine regions and vertically at the first molars. Four different loading conditions with two total forces (120, 300 N) were considered for the numerical analysis. The overdenture displacement was about 2.2 times higher when five mini implants were used rather than four conventional implants. The lowest stress in bone bed was observed with four conventional implants. Stresses in bone were reduced by 61% in model 2 and by 6% in model 3 in comparison to model 1. The highest stress was observed with five mini implants. Stresses in implants were reduced by 76% in model 2 and 89% increased in model 3 compared to model 1. The highest implant displacement was observed with five mini implants. Implant displacements were reduced by 29% in model 2, and increased by 273% in model 3 compared to model 1. Conventional implants proved better stability for overdenture than mini implants. Regardless the type and number of implants, the stress within the bone and implants are below the critical limits.

How Long Can Stool Samples Be Fixed for an Accurate Diagnosis of Soil-Transmitted Helminth Infection Using Mini-FLOTAC?

PubMed Central

Barda, Beatrice; Albonico, Marco; Ianniello, Davide; Ame, Shaali M.; Keiser, Jennifer; Speich, Benjamin; Rinaldi, Laura; Cringoli, Giuseppe; Burioni, Roberto; Montresor, Antonio; Utzinger, Jürg

2015-01-01

Background Kato-Katz is a widely used method for the diagnosis of soil-transmitted helminth infection. Fecal samples cannot be preserved, and hence, should be processed on the day of collection and examined under a microscope within 60 min of slide preparation. Mini-FLOTAC is a technique that allows examining fixed fecal samples. We assessed the performance of Mini-FLOTAC using formalin-fixed stool samples compared to Kato-Katz and determined the dynamics of prevalence and intensity estimates of soil-transmitted helminth infection over a 31-day time period. Methodology The study was carried out in late 2013 on Pemba Island, Tanzania. Forty-one children were enrolled and stool samples were subjected on the day of collection to a single Kato-Katz thick smear and Mini-FLOTAC examination; 12 aliquots of stool were fixed in 5% formalin and subsequently examined by Mini-FLOTAC up to 31 days after collection. Principal Findings The combined results from Kato-Katz and Mini-FLOTAC revealed that 100% of children were positive for Trichuris trichiura, 85% for Ascaris lumbricoides, and 54% for hookworm. Kato-Katz and Mini-FLOTAC techniques found similar prevalence estimates for A. lumbricoides (85% versus 76%), T. trichiura (98% versus 100%), and hookworm (42% versus 51%). The mean eggs per gram of stool (EPG) according to Kato-Katz and Mini-FLOTAC was 12,075 and 11,679 for A. lumbricoides, 1,074 and 1,592 for T. trichiura, and 255 and 220 for hookworm, respectively. The mean EPG from day 1 to 31 of fixation was stable for A. lumbricoides and T. trichiura, but gradually declined for hookworm, starting at day 15. Conclusions/Significance The findings of our study suggest that for a qualitative diagnosis of soil-transmitted helminth infection, stool samples can be fixed in 5% formalin for at least 30 days. However, for an accurate quantitative diagnosis of hookworm, we suggest a limit of 15 days of preservation. Our results have direct implication for integrating soil

The rocks of Gusev Crater as viewed by the Mini-TES instrument

USGS Publications Warehouse

Ruff, S.W.; Christensen, P.R.; Blaney, D.L.; Farrand, W. H.; Johnson, J. R.; Michalski, J.R.; Moersch, J.E.; Wright, S.P.; Squyres, S. W.

2006-01-01

The Miniature Thermal Emission Spectrometer (Mini-TES) on board the Mars Exploration Rover Spirit is part of a payload designed to investigate whether a lake once existed in Gusev Crater. Mini-TES has observed hundreds of rocks along the rover's traverse into the Columbia Hills, yielding information on their distribution, bulk mineralogy, and the potential role of water at the site. Although dust in various forms produces contributions to the spectra, we have established techniques for dealing with it. All of the rocks encountered on the plains traverse from the lander to the base of the Columbia Hills share common spectral features consistent with an olivine-rich basaltic rock known as Adirondack Class. Beginning at the base of the West Spur of the Columbia Hills and across its length, the rocks are spectrally distinct from the plains but can be grouped into a common type called Clovis Class. These rocks, some of which appear as in-place outcrop, are dominated by a component whose spectral character is consistent with unaltered basaltic glass despite evidence from other rover instruments for significant alteration. The northwest flank of Husband Hill is covered in float rocks known as Wishstone Class with spectral features that can be attributed uniquely to plagioclase feldspar, a phase that represents more than half of the bulk mineralogy. Rare exceptions are three classes of basaltic "exotics" found scattered across Husband Hill that may represent impact ejecta and/or float derived from local intrusions within the hills. The rare outcrops observed on Husband Hill display distinctive spectral characteristics. The outcrop called Peace shows a feature attributable to molecular bound water, and the outcrop that hosts the rock called Watchtower displays a dominant basaltic glass component. Despite evidence from the rover's payload for significant alteration of some of the rocks, no unambiguous detection of crystalline phyllosilicates or other secondary silicates has

Appropriate NH4+: NO3- ratio improves low light tolerance of mini Chinese cabbage seedlings.

PubMed

Hu, Linli; Liao, Weibiao; Dawuda, Mohammed Mujitaba; Yu, Jihua; Lv, Jian

2017-01-23

In northwest of China, mini Chinese cabbage (Brassica pekinensis) is highly valued by consumers, and is widely cultivated during winter in solar-greenhouses where low light (LL) fluence (between 85 and 150 μmol m -2 s -1 in day) is a major abiotic stress factor limiting plant growth and crop productivity. The mechanisms with which various NH 4 + : NO 3 - ratios affected growth and photosynthesis of mini Chinese cabbage under normal (200 μmol m -2 s -1 ) and low (100 μmol m -2 s -1 ) light conditions was investigated. The four solutions with different ratios of NH 4 + : NO 3 - applied were 0:100, 10:90, 15:85 and 25:75 with the set up in a glasshouse in hydroponic culture. The most appropriate NH 4 + : NO 3 - ratio that improved the tolerance of mini Chinese cabbage seedlings to LL was found in our current study. Under low light, the application of NH 4 + : NO 3 - (10:90) significantly stimulated growth compared to only NO 3 - by increasing leaf area, canopy spread, biomass accumulation, and net photosynthetic rate. The increase in net photosynthetic rate was associated with an increase in: 1) maximum and effective quantum yield of PSII; 2) activities of Calvin cycle enzymes; and 3) levels of mRNA relative expression of several genes involved in Calvin cycle. In addition, glucose, fructose, sucrose, starch and total carbohydrate, which are the products of CO 2 assimilation, accumulated most in the cabbage leaves that were supplied with NH 4 + : NO 3 - (10:90) under LL condition. Low light reduced the carbohydrate: nitrogen (C: N) ratio while the application of NH 4 + : NO 3 - (10:90) alleviated the negative effect of LL on C: N ratio mainly by increasing total carbohydrate contents. The application of NH 4 + :NO 3 - (10:90) increased rbcL, rbcS, FBA, FBPase and TK expression and/or activities, enhanced photosynthesis, carbohydrate accumulation and improved the tolerance of mini Chinese cabbage seedlings to LL. The results of this study would provide

Political Terrorism: A Mini-Course for High School Social Studies.

ERIC Educational Resources Information Center

Ellington, Lucien

By participating in the 2-week mini-course, high school students will learn that (1) there is a difference between political terror and other criminal activity; (2) governments as well as nongovernmental groups engage in political terrorism; (3) political terrorism has been present throughout history; (4) political terrorism is a world wide…

Lineal energy calibration of mini tissue-equivalent gas-proportional counters (TEPC)

NASA Astrophysics Data System (ADS)

Conte, V.; Moro, D.; Grosswendt, B.; Colautti, P.

2013-07-01

Mini TEPCs are cylindrical gas proportional counters of 1 mm or less of sensitive volume diameter. The lineal energy calibration of these tiny counters can be performed with an external gamma-ray source. However, to do that, first a method to get a simple and precise spectral mark has to be found and then the keV/μm value of this mark. A precise method (less than 1% of uncertainty) to identify this markis described here, and the lineal energy value of this mark has been measured for different simulated site sizes by using a 137Cs gamma source and a cylindrical TEPC equipped with a precision internal 244Cm alpha-particle source, and filled with propane-based tissue-equivalent gas mixture. Mini TEPCs can be calibrated in terms of lineal energy, by exposing them to 137Cesium sources, with an overall uncertainty of about 5%.

Bringing mini-chalk talks to the bedside to enhance clinical teaching.

PubMed

Pitt, Michael B; Orlander, Jay D

2017-01-01

Chalk talks - where the teacher is equipped solely with a writing utensil and a writing surface - have been used for centuries, yet little has been written about strategies for their use in medical education. Structured education proximal to patient encounters (during rounds, at the bedside, or in between patients in clinic) maximizes the opportunities for clinical learning. This paper presents a strategy to bring mini-chalk talks (MCTs) to the bedside as a practical way to provide relevant clinical teaching by visually framing teachable moments. Grounded in adult learning theory, MCTs leverage teaching scripts to facilitate discussion, involve learners at multiple levels, and embrace the increased retention associated with visual aids. These authors provide specific recommendations for the design and implementation of MCT sessions including what topics work well, how to prepare, and how to involve and engage the learners. ADHD: Attention Deficit Hyperactivity Disorder; MCT: Mini-chalk talks.

UAS Integration in the NAS Project: DAA-TCAS Interoperability "mini" HITL Primary Results

NASA Technical Reports Server (NTRS)

Rorie, Conrad; Fern, Lisa; Shively, Jay; Santiago, Confesor

2016-01-01

At the May 2015 SC-228 meeting, requirements for TCAS II interoperability became elevated in priority. A TCAS interoperability workgroup was formed to identify and address key issues/questions. The TCAS workgroup came up with an initial list of questions and a plan to address those questions. As part of that plan, NASA proposed to run a mini HITL to address display, alerting and guidance issues. A TCAS Interoperability Workshop was held to determine potential display/alerting/guidance issues that could be explored in future NASA mini HITLS. Consensus on main functionality of DAA guidance when TCAS II RA occurs. Prioritized list of independent variables for experimental design. Set of use cases to stress TCAS Interoperability.

Stress and strain distribution in three different mini dental implant designs using in implant retained overdenture: a finite element analysis study

PubMed Central

AUNMEUNGTONG, W.; KHONGKHUNTHIAN, P.; RUNGSIYAKULL, P.

2016-01-01

SUMMARY Finite Element Analysis (FEA) has been used for prediction of stress and strain between dental implant components and bone in the implant design process. Purpose Purpose of this study was to characterize and analyze stress and strain distribution occurring in bone and implants and to compare stress and strain of three different implant designs. Materials and methods Three different mini dental implant designs were included in this study: 1. a mini dental implant with an internal implant-abutment connection (MDIi); 2. a mini dental implant with an external implant-abutment connection (MDIe); 3. a single piece mini dental implant (MDIs). All implant designs were scanned using micro-CT scans. The imaging details of the implants were used to simulate models for FEA. An artificial bone volume of 9×9 mm in size was constructed and each implant was placed separately at the center of each bone model. All bone-implant models were simulatively loaded under an axial compressive force of 100 N and a 45-degree force of 100 N loading at the top of the implants using computer software to evaluate stress and strain distribution. Results There was no difference in stress or strain between the three implant designs. The stress and strain occurring in all three mini dental implant designs were mainly localized at the cortical bone around the bone-implant interface. Oblique 45° loading caused increased deformation, magnitude and distribution of stress and strain in all implant models. Conclusions Within the limits of this study, the average stress and strain in bone and implant models with MDIi were similar to those with MDIe and MDIs. The oblique 45° load played an important role in dramatically increased average stress and strain in all bone-implant models. Clinical implications Mini dental implants with external or internal connections have similar stress distribution to single piece mini dental implants. In clinical situations, the three types of mini dental implant

Stress and strain distribution in three different mini dental implant designs using in implant retained overdenture: a finite element analysis study.

PubMed

Aunmeungtong, W; Khongkhunthian, P; Rungsiyakull, P

2016-01-01

Finite Element Analysis (FEA) has been used for prediction of stress and strain between dental implant components and bone in the implant design process. Purpose of this study was to characterize and analyze stress and strain distribution occurring in bone and implants and to compare stress and strain of three different implant designs. Three different mini dental implant designs were included in this study: 1. a mini dental implant with an internal implant-abutment connection (MDIi); 2. a mini dental implant with an external implant-abutment connection (MDIe); 3. a single piece mini dental implant (MDIs). All implant designs were scanned using micro-CT scans. The imaging details of the implants were used to simulate models for FEA. An artificial bone volume of 9×9 mm in size was constructed and each implant was placed separately at the center of each bone model. All bone-implant models were simulatively loaded under an axial compressive force of 100 N and a 45-degree force of 100 N loading at the top of the implants using computer software to evaluate stress and strain distribution. There was no difference in stress or strain between the three implant designs. The stress and strain occurring in all three mini dental implant designs were mainly localized at the cortical bone around the bone-implant interface. Oblique 45° loading caused increased deformation, magnitude and distribution of stress and strain in all implant models. Within the limits of this study, the average stress and strain in bone and implant models with MDIi were similar to those with MDIe and MDIs. The oblique 45° load played an important role in dramatically increased average stress and strain in all bone-implant models. Mini dental implants with external or internal connections have similar stress distribution to single piece mini dental implants. In clinical situations, the three types of mini dental implant should exhibit the same behavior to chewing force.

Spirit Mini-TES Observations: From Bonneville Crater to the Columbia Hills.

NASA Astrophysics Data System (ADS)

Blaney, D. L.; Athena Science

2004-11-01

During the Mars Exploration Rover Extended Mission the Spirit rover traveled from the rim of the crater informally known as "Bonneville, Crater" into the hills informally known as the "Columbia Hills" in Gusev Crater. During this >3 km drive Mini-TES (Miniature Thermal Emission Spectrometer) collected systematic observations to characterize spectral diversity and targeted observations of rocks, soils, rover tracks, and trenches. Surface temperatures have steadily decreased during the drive and arrival into the Columbia hills with the approach of winter. Mini-TES covers the 5-29 micron spectral region with a 20 mrad aperture that is co-registered with panoramic and navigation cameras. As at the landing site (Christensen et al., Science, 2004), many dark rocks in the plains between "Bonneville Crater" show long wavelength (15-25 μm) absorptions due to olivine consistent with the detection of olivine-bearing basalt at this site from orbital TES infrared spectroscopy. Rocks with the spectral signature of olivine are rarer in the Columbia Hills. Measurements of outcrops of presumably intact bedrock lack any olivine signature and are consistent with other results indicating that these rocks are highly altered. Rock coatings and fine dust on rocks are common. Soils have thin dust coatings and disturbed soil (e.g rover tracks and trenches) are consistent with basalt. Mini-TES observations were coordinated with Panoramic Camera (Pancam) observations to allow us to search for correlations of visible spectra properties with infrared. This work was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract to NASA.

Morphometry, ultrastructure, myosin isoforms, and metabolic capacities of the "mini muscles" favoured by selection for high activity in house mice.

PubMed

Guderley, Helga; Houle-Leroy, Philippe; Diffee, Gary M; Camp, Dana M; Garland, Theodore

2006-07-01

Prolonged selective breeding of mice (Mus musculus) for high levels of voluntary wheel running has favoured an unusual phenotype ("mini muscles"), apparently caused by a single Mendelian recessive allele, in which most hind-limb muscles are markedly reduced in mass, but have increased mass-specific activities of mitochondrial enzymes. We examined whether these changes reflect changes in fibre size, number or ultrastructure in normal and "mini-muscle" mice within the two (of four) selectively bred lines (lab designations L3 and L6) that exhibit the phenotype at generations 26 and 27. In both lines, the gastrocnemius and plantaris muscles are smaller in mass (by >50% and 20%, respectively) in affected individuals. The mass-specific activities of mitochondrial enzymes in the gastrocnemius and plantaris muscles were increased in the mini phenotype in both lines, with stronger effects in the gastrocnemius muscle. In the gastrocnemius, the % myosin heavy chain (MHC) IIb was reduced by 50% in L3 and by 30% in L6, whereas the % MHC IIa and I were higher, particularly in L3. Fibre number in the plantaris muscle did not significantly differ between mini and normal muscles, although muscle mass was a significant positive correlate of fibre number. Small fibres were more abundant in mini than normal muscles in L3. Mitochondrial volume density was significantly higher in mini than normal muscle fibres in L3, but not in L6. Microscopy revealed a surprising attribute of the mini muscles: an abundance of small, minimally differentiated, myofibril-containing cells positioned in a disorderly fashion, particularly in the surface layer. We hypothesise that these unusual cells may be satellite cells or type IIb fibres that did not complete their differentiation. Together, these observations suggest that mice with the mini phenotype have reduced numbers of type IIb fibres in many of their hind-limb muscles, leading to a decrease in mass and an increase in mass-specific aerobic capacity

Mini-CME eruptions in a flux emergence event in a coronal hole environment

NASA Astrophysics Data System (ADS)

Galsgaard, K.; Moreno-Insertis, F.

2016-10-01

Small scale jets are observed to take place at the interface between the open magnetic field in coronal holes and bipolar magnetic field concentrations. A fraction of these shows an eruptive behavior, where a combination of cold dense and hot light plasma has been observed to propagate out along the jet region, combining traditional jets with what looks like the eruption of mini-CMEs. Here we discuss a simple model scenario for the explosive energy release process that leads to a mixture of hot and cold plasma being accelerated upwards simultaneously. The model explains both the typical steady state inverted-Y jet and the subsequent mini-CME eruptions found in blowout jets. The numerical experiment consists of a buoyant unstable flux rope that emerges into an overlying slanted coronal field, thereby creating a bipolar magnetic field distribution in the photosphere with coronal loops linking the polarities. Reconnection between the emerged and preexisting magnetic systems including the launching of a classical inverted-Y jet. The experiment shows that this simple model provides for a very complicated dynamical behavior in its late phases. Five independent mini-CME eruptions follow the initial near steady-state jet phase. The first one is a direct consequence of the reconnection of the emerged magnetic flux, is mediated by the formation of a strongly sheared arcade followed by a tether-cutting reconnection process, and leads to the eruption of a twisted flux rope. The final four explosive eruptions, instead, are preceded by the formation of a twisted torus-like flux rope near the strong magnetic concentrations at the photosphere. As the tube center starts emerging an internal current sheet is formed below it. This sheet experiences a tether cutting process that provides the important upwards kick of the newly formed mini-CME structure. As the fast rising cold and dense tube interacts with the overlying magnetic field, it reconnects at different spatial locations