Sample records for x3d operational visualization

  1. Rapid fusion of 2D X-ray fluoroscopy with 3D multislice CT for image-guided electrophysiology procedures

    NASA Astrophysics Data System (ADS)

    Zagorchev, Lyubomir; Manzke, Robert; Cury, Ricardo; Reddy, Vivek Y.; Chan, Raymond C.

    2007-03-01

    Interventional cardiac electrophysiology (EP) procedures are typically performed under X-ray fluoroscopy for visualizing catheters and EP devices relative to other highly-attenuating structures such as the thoracic spine and ribs. These projections do not however contain information about soft-tissue anatomy and there is a recognized need for fusion of conventional fluoroscopy with pre-operatively acquired cardiac multislice computed tomography (MSCT) volumes. Rapid 2D-3D integration in this application would allow for real-time visualization of all catheters present within the thorax in relation to the cardiovascular anatomy visible in MSCT. We present a method for rapid fusion of 2D X-ray fluoroscopy with 3DMSCT that can facilitate EP mapping and interventional procedures by reducing the need for intra-operative contrast injections to visualize heart chambers and specialized systems to track catheters within the cardiovascular anatomy. We use hardware-accelerated ray-casting to compute digitally reconstructed radiographs (DRRs) from the MSCT volume and iteratively optimize the rigid-body pose of the volumetric data to maximize the similarity between the MSCT-derived DRR and the intra-operative X-ray projection data.

  2. Towards clinical translation of augmented orthopedic surgery: from pre-op CT to intra-op x-ray via RGBD sensing

    NASA Astrophysics Data System (ADS)

    Tucker, Emerson; Fotouhi, Javad; Unberath, Mathias; Lee, Sing Chun; Fuerst, Bernhard; Johnson, Alex; Armand, Mehran; Osgood, Greg M.; Navab, Nassir

    2018-03-01

    Pre-operative CT data is available for several orthopedic and trauma interventions, and is mainly used to identify injuries and plan the surgical procedure. In this work we propose an intuitive augmented reality environment allowing visualization of pre-operative data during the intervention, with an overlay of the optical information from the surgical site. The pre-operative CT volume is first registered to the patient by acquiring a single C-arm X-ray image and using 3D/2D intensity-based registration. Next, we use an RGBD sensor on the C-arm to fuse the optical information of the surgical site with patient pre-operative medical data and provide an augmented reality environment. The 3D/2D registration of the pre- and intra-operative data allows us to maintain a correct visualization each time the C-arm is repositioned or the patient moves. An overall mean target registration error (mTRE) and standard deviation of 5.24 +/- 3.09 mm was measured averaged over 19 C-arm poses. The proposed solution enables the surgeon to visualize pre-operative data overlaid with information from the surgical site (e.g. surgeon's hands, surgical tools, etc.) for any C-arm pose, and negates issues of line-of-sight and long setup times, which are present in commercially available systems.

  3. NoSQL Based 3D City Model Management System

    NASA Astrophysics Data System (ADS)

    Mao, B.; Harrie, L.; Cao, J.; Wu, Z.; Shen, J.

    2014-04-01

    To manage increasingly complicated 3D city models, a framework based on NoSQL database is proposed in this paper. The framework supports import and export of 3D city model according to international standards such as CityGML, KML/COLLADA and X3D. We also suggest and implement 3D model analysis and visualization in the framework. For city model analysis, 3D geometry data and semantic information (such as name, height, area, price and so on) are stored and processed separately. We use a Map-Reduce method to deal with the 3D geometry data since it is more complex, while the semantic analysis is mainly based on database query operation. For visualization, a multiple 3D city representation structure CityTree is implemented within the framework to support dynamic LODs based on user viewpoint. Also, the proposed framework is easily extensible and supports geoindexes to speed up the querying. Our experimental results show that the proposed 3D city management system can efficiently fulfil the analysis and visualization requirements.

  4. Modeling Airport Ground Operations using Discrete Event Simulation (DES) and X3D Visualization

    DTIC Science & Technology

    2008-03-01

    scenes. It is written in open-source Java and XML using the Netbeans platform, which gave the features of being suitable as standalone applications...and as a plug-in module for the Netbeans integrated development environment (IDE). X3D Graphics is the tool used for the elaboration the creation of...process is shown in Figure 2. To 20 create a new event graph in Viskit, first, Viskit tool must be launched via Netbeans or from the executable

  5. Distributed 3D Information Visualization - Towards Integration of the Dynamic 3D Graphics and Web Services

    NASA Astrophysics Data System (ADS)

    Vucinic, Dean; Deen, Danny; Oanta, Emil; Batarilo, Zvonimir; Lacor, Chris

    This paper focuses on visualization and manipulation of graphical content in distributed network environments. The developed graphical middleware and 3D desktop prototypes were specialized for situational awareness. This research was done in the LArge Scale COllaborative decision support Technology (LASCOT) project, which explored and combined software technologies to support human-centred decision support system for crisis management (earthquake, tsunami, flooding, airplane or oil-tanker incidents, chemical, radio-active or other pollutants spreading, etc.). The performed state-of-the-art review did not identify any publicly available large scale distributed application of this kind. Existing proprietary solutions rely on the conventional technologies and 2D representations. Our challenge was to apply the "latest" available technologies, such Java3D, X3D and SOAP, compatible with average computer graphics hardware. The selected technologies are integrated and we demonstrate: the flow of data, which originates from heterogeneous data sources; interoperability across different operating systems and 3D visual representations to enhance the end-users interactions.

  6. Biomechanical ToolKit: Open-source framework to visualize and process biomechanical data.

    PubMed

    Barre, Arnaud; Armand, Stéphane

    2014-04-01

    C3D file format is widely used in the biomechanical field by companies and laboratories to store motion capture systems data. However, few software packages can visualize and modify the integrality of the data in the C3D file. Our objective was to develop an open-source and multi-platform framework to read, write, modify and visualize data from any motion analysis systems using standard (C3D) and proprietary file formats (used by many companies producing motion capture systems). The Biomechanical ToolKit (BTK) was developed to provide cost-effective and efficient tools for the biomechanical community to easily deal with motion analysis data. A large panel of operations is available to read, modify and process data through C++ API, bindings for high-level languages (Matlab, Octave, and Python), and standalone application (Mokka). All these tools are open-source and cross-platform and run on all major operating systems (Windows, Linux, MacOS X). Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  7. Using XML/HTTP to Store, Serve and Annotate Tactical Scenarios for X3D Operational Visualization and Anti-Terrorist Training

    DTIC Science & Technology

    2003-03-01

    PXSLServlet Paul A. Open Source Relational x X 23 Tchistopolskii sql2dtd David Mertz Public domain Relational x -- sql2xml Scott Hathaway Public...March 2003. [Hunter 2001] Hunter, David ; Cagle, Kurt; Dix, Chris; Kovack, Roger; Pinnock, Jonathan, Rafter, Jeff; Beginning XML (2nd Edition...Postgraduate School Monterey, California 4. Curt Blais Naval Postgraduate School Monterey, California 5 Erik Chaum NAVSEA Undersea

  8. A Hybrid Synthetic Vision System for the Tele-operation of Unmanned Vehicles

    NASA Technical Reports Server (NTRS)

    Delgado, Frank; Abernathy, Mike

    2004-01-01

    A system called SmartCam3D (SC3D) has been developed to provide enhanced situational awareness for operators of a remotely piloted vehicle. SC3D is a Hybrid Synthetic Vision System (HSVS) that combines live sensor data with information from a Synthetic Vision System (SVS). By combining the dual information sources, the operators are afforded the advantages of each approach. The live sensor system provides real-time information for the region of interest. The SVS provides information rich visuals that will function under all weather and visibility conditions. Additionally, the combination of technologies allows the system to circumvent some of the limitations from each approach. Video sensor systems are not very useful when visibility conditions are hampered by rain, snow, sand, fog, and smoke, while a SVS can suffer from data freshness problems. Typically, an aircraft or satellite flying overhead collects the data used to create the SVS visuals. The SVS data could have been collected weeks, months, or even years ago. To that extent, the information from an SVS visual could be outdated and possibly inaccurate. SC3D was used in the remote cockpit during flight tests of the X-38 132 and 131R vehicles at the NASA Dryden Flight Research Center. SC3D was also used during the operation of military Unmanned Aerial Vehicles. This presentation will provide an overview of the system, the evolution of the system, the results of flight tests, and future plans. Furthermore, the safety benefits of the SC3D over traditional and pure synthetic vision systems will be discussed.

  9. Improving the visualization of 3D ultrasound data with 3D filtering

    NASA Astrophysics Data System (ADS)

    Shamdasani, Vijay; Bae, Unmin; Managuli, Ravi; Kim, Yongmin

    2005-04-01

    3D ultrasound imaging is quickly gaining widespread clinical acceptance as a visualization tool that allows clinicians to obtain unique views not available with traditional 2D ultrasound imaging and an accurate understanding of patient anatomy. The ability to acquire, manipulate and interact with the 3D data in real time is an important feature of 3D ultrasound imaging. Volume rendering is often used to transform the 3D volume into 2D images for visualization. Unlike computed tomography (CT) and magnetic resonance imaging (MRI), volume rendering of 3D ultrasound data creates noisy images in which surfaces cannot be readily discerned due to speckles and low signal-to-noise ratio. The degrading effect of speckles is especially severe when gradient shading is performed to add depth cues to the image. Several researchers have reported that smoothing the pre-rendered volume with a 3D convolution kernel, such as 5x5x5, can significantly improve the image quality, but at the cost of decreased resolution. In this paper, we have analyzed the reasons for the improvement in image quality with 3D filtering and determined that the improvement is due to two effects. The filtering reduces speckles in the volume data, which leads to (1) more accurate gradient computation and better shading and (2) decreased noise during compositing. We have found that applying a moderate-size smoothing kernel (e.g., 7x7x7) to the volume data before gradient computation combined with some smoothing of the volume data (e.g., with a 3x3x3 lowpass filter) before compositing yielded images with good depth perception and no appreciable loss in resolution. Providing the clinician with the flexibility to control both of these effects (i.e., shading and compositing) independently could improve the visualization of the 3D ultrasound data. Introducing this flexibility into the ultrasound machine requires 3D filtering to be performed twice on the volume data, once before gradient computation and again before compositing. 3D filtering of an ultrasound volume containing millions of voxels requires a large amount of computation, and doing it twice decreases the number of frames that can be visualized per second. To address this, we have developed several techniques to make computation efficient. For example, we have used the moving average method to filter a 128x128x128 volume with a 3x3x3 boxcar kernel in 17 ms on a single MAP processor running at 400 MHz. The same methods reduced the computing time on a Pentium 4 running at 3 GHz from 110 ms to 62 ms. We believe that our proposed method can improve 3D ultrasound visualization without sacrificing resolution and incurring an excessive computing time.

  10. A framework for breast cancer visualization using augmented reality x-ray vision technique in mobile technology

    NASA Astrophysics Data System (ADS)

    Rahman, Hameedur; Arshad, Haslina; Mahmud, Rozi; Mahayuddin, Zainal Rasyid

    2017-10-01

    Breast Cancer patients who require breast biopsy has increased over the past years. Augmented Reality guided core biopsy of breast has become the method of choice for researchers. However, this cancer visualization has limitations to the extent of superimposing the 3D imaging data only. In this paper, we are introducing an Augmented Reality visualization framework that enables breast cancer biopsy image guidance by using X-Ray vision technique on a mobile display. This framework consists of 4 phases where it initially acquires the image from CT/MRI and process the medical images into 3D slices, secondly it will purify these 3D grayscale slices into 3D breast tumor model using 3D modeling reconstruction technique. Further, in visualization processing this virtual 3D breast tumor model has been enhanced using X-ray vision technique to see through the skin of the phantom and the final composition of it is displayed on handheld device to optimize the accuracy of the visualization in six degree of freedom. The framework is perceived as an improved visualization experience because the Augmented Reality x-ray vision allowed direct understanding of the breast tumor beyond the visible surface and direct guidance towards accurate biopsy targets.

  11. Indoor space 3D visual reconstruction using mobile cart with laser scanner and cameras

    NASA Astrophysics Data System (ADS)

    Gashongore, Prince Dukundane; Kawasue, Kikuhito; Yoshida, Kumiko; Aoki, Ryota

    2017-02-01

    Indoor space 3D visual reconstruction has many applications and, once done accurately, it enables people to conduct different indoor activities in an efficient manner. For example, an effective and efficient emergency rescue response can be accomplished in a fire disaster situation by using 3D visual information of a destroyed building. Therefore, an accurate Indoor Space 3D visual reconstruction system which can be operated in any given environment without GPS has been developed using a Human-Operated mobile cart equipped with a laser scanner, CCD camera, omnidirectional camera and a computer. By using the system, accurate indoor 3D Visual Data is reconstructed automatically. The obtained 3D data can be used for rescue operations, guiding blind or partially sighted persons and so forth.

  12. Advanced Data Visualization in Astrophysics: The X3D Pathway

    NASA Astrophysics Data System (ADS)

    Vogt, Frédéric P. A.; Owen, Chris I.; Verdes-Montenegro, Lourdes; Borthakur, Sanchayeeta

    2016-02-01

    Most modern astrophysical data sets are multi-dimensional; a characteristic that can nowadays generally be conserved and exploited scientifically during the data reduction/simulation and analysis cascades. However, the same multi-dimensional data sets are systematically cropped, sliced, and/or projected to printable two-dimensional diagrams at the publication stage. In this article, we introduce the concept of the “X3D pathway” as a mean of simplifying and easing the access to data visualization and publication via three-dimensional (3D) diagrams. The X3D pathway exploits the facts that (1) the X3D 3D file format lies at the center of a product tree that includes interactive HTML documents, 3D printing, and high-end animations, and (2) all high-impact-factor and peer-reviewed journals in astrophysics are now published (some exclusively) online. We argue that the X3D standard is an ideal vector for sharing multi-dimensional data sets because it provides direct access to a range of different data visualization techniques, is fully open source, and is a well-defined standard from the International Organization for Standardization. Unlike other earlier propositions to publish multi-dimensional data sets via 3D diagrams, the X3D pathway is not tied to specific software (prone to rapid and unexpected evolution), but instead is compatible with a range of open-source software already in use by our community. The interactive HTML branch of the X3D pathway is also actively supported by leading peer-reviewed journals in the field of astrophysics. Finally, this article provides interested readers with a detailed set of practical astrophysical examples designed to act as a stepping stone toward the implementation of the X3D pathway for any other data set.

  13. 3D Exploration of Meteorological Data: Facing the challenges of operational forecasters

    NASA Astrophysics Data System (ADS)

    Koutek, Michal; Debie, Frans; van der Neut, Ian

    2016-04-01

    In the past years the Royal Netherlands Meteorological Institute (KNMI) has been working on innovation in the field of meteorological data visualization. We are dealing with Numerical Weather Prediction (NWP) model data and observational data, i.e. satellite images, precipitation radar, ground and air-borne measurements. These multidimensional multivariate data are geo-referenced and can be combined in 3D space to provide more intuitive views on the atmospheric phenomena. We developed the Weather3DeXplorer (W3DX), a visualization framework for processing and interactive exploration and visualization using Virtual Reality (VR) technology. We managed to have great successes with research studies on extreme weather situations. In this paper we will elaborate what we have learned from application of interactive 3D visualization in the operational weather room. We will explain how important it is to control the degrees-of-freedom during interaction that are given to the users: forecasters/scientists; (3D camera and 3D slicing-plane navigation appear to be rather difficult for the users, when not implemented properly). We will present a novel approach of operational 3D visualization user interfaces (UI) that for a great deal eliminates the obstacle and the time it usually takes to set up the visualization parameters and an appropriate camera view on a certain atmospheric phenomenon. We have found our inspiration in the way our operational forecasters work in the weather room. We decided to form a bridge between 2D visualization images and interactive 3D exploration. Our method combines WEB-based 2D UI's, pre-rendered 3D visualization catalog for the latest NWP model runs, with immediate entry into interactive 3D session for selected visualization setting. Finally, we would like to present the first user experiences with this approach.

  14. The Human Side of Cyber Conflict: Organizing, Training, and Equipping the Air Force Cyber Workforce

    DTIC Science & Technology

    2016-06-01

    Breakdown of the 17D community as of 31 March 2014. (Reproduced from 17D Officer Assignment Team, Cyberspace Operations “Spread the Word” briefing, 9– 11 ...surety 3D0X4 Computer systems programs 3D1X1 Client systems 3D1X2 Cyber transport 3D1X3 Radio frequency transport 3D1X4 Spectrum operations 3D1X5 Radar...Computer systems programs 3D1X1 Client systems 3D1X2 Cyber transport systems 3D1X3 Radio frequency transmissionsystems FORCE DEVELOPMENT │ 123 Table 8

  15. [Design of visualized medical images network and web platform based on MeVisLab].

    PubMed

    Xiang, Jun; Ye, Qing; Yuan, Xun

    2017-04-01

    With the trend of the development of "Internet +", some further requirements for the mobility of medical images have been required in the medical field. In view of this demand, this paper presents a web-based visual medical imaging platform. First, the feasibility of medical imaging is analyzed and technical points. CT (Computed Tomography) or MRI (Magnetic Resonance Imaging) images are reconstructed three-dimensionally by MeVisLab and packaged as X3D (Extensible 3D Graphics) files shown in the present paper. Then, the B/S (Browser/Server) system specially designed for 3D image is designed by using the HTML 5 and WebGL rendering engine library, and the X3D image file is parsed and rendered by the system. The results of this study showed that the platform was suitable for multiple operating systems to realize the platform-crossing and mobilization of medical image data. The development of medical imaging platform is also pointed out in this paper. It notes that web application technology will not only promote the sharing of medical image data, but also facilitate image-based medical remote consultations and distance learning.

  16. Toward the establishment of design guidelines for effective 3D perspective interfaces

    NASA Astrophysics Data System (ADS)

    Fitzhugh, Elisabeth; Dixon, Sharon; Aleva, Denise; Smith, Eric; Ghrayeb, Joseph; Douglas, Lisa

    2009-05-01

    The propagation of information operation technologies, with correspondingly vast amounts of complex network information to be conveyed, significantly impacts operator workload. Information management research is rife with efforts to develop schemes to aid operators to identify, review, organize, and retrieve the wealth of available data. Data may take on such distinct forms as intelligence libraries, logistics databases, operational environment models, or network topologies. Increased use of taxonomies and semantic technologies opens opportunities to employ network visualization as a display mechanism for diverse information aggregations. The broad applicability of network visualizations is still being tested, but in current usage, the complexity of densely populated abstract networks suggests the potential utility of 3D. Employment of 2.5D in network visualization, using classic perceptual cues, creates a 3D experience within a 2D medium. It is anticipated that use of 3D perspective (2.5D) will enhance user ability to visually inspect large, complex, multidimensional networks. Current research for 2.5D visualizations demonstrates that display attributes, including color, shape, size, lighting, atmospheric effects, and shadows, significantly impact operator experience. However, guidelines for utilization of attributes in display design are limited. This paper discusses pilot experimentation intended to identify potential problem areas arising from these cues and determine how best to optimize perceptual cue settings. Development of optimized design guidelines will ensure that future experiments, comparing network displays with other visualizations, are not confounded or impeded by suboptimal attribute characterization. Current experimentation is anticipated to support development of cost-effective, visually effective methods to implement 3D in military applications.

  17. Retrieving spin textures on curved magnetic thin films with full-field soft X-ray microscopies

    DOE PAGES

    Streubel, Robert; Kronast, Florian; Fischer, Peter; ...

    2015-07-03

    X-ray tomography is a well-established technique to characterize 3D structures in material sciences and biology; its magnetic analogue—magnetic X-ray tomography—is yet to be developed. We demonstrate the visualization and reconstruction of magnetic domain structures in a 3D curved magnetic thin films with tubular shape by means of full-field soft X-ray microscopies. In the 3D arrangement of the magnetization is retrieved from a set of 2D projections by analysing the evolution of the magnetic contrast with varying projection angle. By using reconstruction algorithms to analyse the angular evolution of 2D projections provides quantitative information about domain patterns and magnetic coupling phenomenamore » between windings of azimuthally and radially magnetized tubular objects. In conclusion, the present approach represents a first milestone towards visualizing magnetization textures of 3D curved thin films with virtually arbitrary shape.« less

  18. Retrieving spin textures on curved magnetic thin films with full-field soft X-ray microscopies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Streubel, Robert; Kronast, Florian; Fischer, Peter

    X-ray tomography is a well-established technique to characterize 3D structures in material sciences and biology; its magnetic analogue—magnetic X-ray tomography—is yet to be developed. We demonstrate the visualization and reconstruction of magnetic domain structures in a 3D curved magnetic thin films with tubular shape by means of full-field soft X-ray microscopies. In the 3D arrangement of the magnetization is retrieved from a set of 2D projections by analysing the evolution of the magnetic contrast with varying projection angle. By using reconstruction algorithms to analyse the angular evolution of 2D projections provides quantitative information about domain patterns and magnetic coupling phenomenamore » between windings of azimuthally and radially magnetized tubular objects. In conclusion, the present approach represents a first milestone towards visualizing magnetization textures of 3D curved thin films with virtually arbitrary shape.« less

  19. Environmental Assessment for Enhanced Use Lease of U.S. Air Force Lands to the City of North Las Vegas for Construction and Operation of a Water Reclamation Facility, Nellis Air Force Base, Nevada

    DTIC Science & Technology

    2008-01-01

    3.1.14 Soundscape ........................................................................................................ 13 3.1.15 Visual Resources...Health and Safety – X Socioeconomic X – Indian Trust Assets – X Native American Religious Concerns – X Soundscape – X Visual Resources – X Odor – X...3.1.14 Soundscape Detailed consideration of the soundscape was not deemed necessary in this EA. Because the proposed Water Reclamation Facility is

  20. Fusion of CTA and XA data using 3D centerline registration for plaque visualization during coronary intervention

    NASA Astrophysics Data System (ADS)

    Kaila, Gaurav; Kitslaar, Pieter; Tu, Shengxian; Penicka, Martin; Dijkstra, Jouke; Lelieveldt, Boudewijn

    2016-03-01

    Coronary Artery Disease (CAD) results in the buildup of plaque below the intima layer inside the vessel wall of the coronary arteries causing narrowing of the vessel and obstructing blood flow. Percutaneous coronary intervention (PCI) is usually done to enlarge the vessel lumen and regain back normal flow of blood to the heart. During PCI, X-ray imaging is done to assist guide wire movement through the vessels to the area of stenosis. While X-ray imaging allows for good lumen visualization, information on plaque type is unavailable. Also due to the projection nature of the X-ray imaging, additional drawbacks such as foreshortening and overlap of vessels limit the efficacy of the cardiac intervention. Reconstruction of 3D vessel geometry from biplane X-ray acquisitions helps to overcome some of these projection drawbacks. However, the plaque type information remains an issue. In contrast, imaging using computed tomography angiography (CTA) can provide us with information on both lumen and plaque type and allows us to generate a complete 3D coronary vessel tree unaffected by the foreshortening and overlap problems of the X-ray imaging. In this paper, we combine x-ray biplane images with CT angiography to visualize three plaque types (dense calcium, fibrous fatty and necrotic core) on x-ray images. 3D registration using three different registration methods is done between coronary centerlines available from x-ray images and from the CTA volume along with 3D plaque information available from CTA. We compare the different registration methods and evaluate their performance based on 3D root mean squared errors. Two methods are used to project this 3D information onto 2D plane of the x-ray biplane images. Validation of our approach is performed using artificial biplane x-ray datasets.

  1. Unimpeded permeation of water through biocidal graphene oxide sheets anchored on to 3D porous polyolefinic membranes

    NASA Astrophysics Data System (ADS)

    Mural, Prasanna Kumar S.; Jain, Shubham; Kumar, Sachin; Madras, Giridhar; Bose, Suryasarathi

    2016-04-01

    3D porous membranes were developed by etching one of the phases (here PEO, polyethylene oxide) from melt-mixed PE/PEO binary blends. Herein, we have systematically discussed the development of these membranes using X-ray micro-computed tomography. The 3D tomograms of the extruded strands and hot-pressed samples revealed a clear picture as to how the morphology develops and coarsens over a function of time during post-processing operations like compression molding. The coarsening of PE/PEO blends was traced using X-ray micro-computed tomography and scanning electron microscopy (SEM) of annealed blends at different times. It is now understood from X-ray micro-computed tomography that by the addition of a compatibilizer (here lightly maleated PE), a stable morphology can be visualized in 3D. In order to anchor biocidal graphene oxide sheets onto these 3D porous membranes, the PE membranes were chemically modified with acid/ethylene diamine treatment to anchor the GO sheets which were further confirmed by Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and surface Raman mapping. The transport properties through the membrane clearly reveal unimpeded permeation of water which suggests that anchoring GO on to the membranes does not clog the pores. Antibacterial studies through the direct contact of bacteria with GO anchored PE membranes resulted in 99% of bacterial inactivation. The possible bacterial inactivation through physical disruption of the bacterial cell wall and/or reactive oxygen species (ROS) is discussed herein. Thus this study opens new avenues in designing polyolefin based antibacterial 3D porous membranes for water purification.3D porous membranes were developed by etching one of the phases (here PEO, polyethylene oxide) from melt-mixed PE/PEO binary blends. Herein, we have systematically discussed the development of these membranes using X-ray micro-computed tomography. The 3D tomograms of the extruded strands and hot-pressed samples revealed a clear picture as to how the morphology develops and coarsens over a function of time during post-processing operations like compression molding. The coarsening of PE/PEO blends was traced using X-ray micro-computed tomography and scanning electron microscopy (SEM) of annealed blends at different times. It is now understood from X-ray micro-computed tomography that by the addition of a compatibilizer (here lightly maleated PE), a stable morphology can be visualized in 3D. In order to anchor biocidal graphene oxide sheets onto these 3D porous membranes, the PE membranes were chemically modified with acid/ethylene diamine treatment to anchor the GO sheets which were further confirmed by Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and surface Raman mapping. The transport properties through the membrane clearly reveal unimpeded permeation of water which suggests that anchoring GO on to the membranes does not clog the pores. Antibacterial studies through the direct contact of bacteria with GO anchored PE membranes resulted in 99% of bacterial inactivation. The possible bacterial inactivation through physical disruption of the bacterial cell wall and/or reactive oxygen species (ROS) is discussed herein. Thus this study opens new avenues in designing polyolefin based antibacterial 3D porous membranes for water purification. Electronic supplementary information (ESI) available: SEM micrographs of porous PE with and without maleated PE, X-ray micro-computed tomogram of porous extruded PE, FTIR spectra of GO, XPS wide spectra of untreated and GO immobilized PE and Raman spectra of PE and GO. See DOI: 10.1039/c6nr01356b

  2. Techniques for efficient, real-time, 3D visualization of multi-modality cardiac data using consumer graphics hardware.

    PubMed

    Levin, David; Aladl, Usaf; Germano, Guido; Slomka, Piotr

    2005-09-01

    We exploit consumer graphics hardware to perform real-time processing and visualization of high-resolution, 4D cardiac data. We have implemented real-time, realistic volume rendering, interactive 4D motion segmentation of cardiac data, visualization of multi-modality cardiac data and 3D display of multiple series cardiac MRI. We show that an ATI Radeon 9700 Pro can render a 512x512x128 cardiac Computed Tomography (CT) study at 0.9 to 60 frames per second (fps) depending on rendering parameters and that 4D motion based segmentation can be performed in real-time. We conclude that real-time rendering and processing of cardiac data can be implemented on consumer graphics cards.

  3. Differintegration: The One Branch of Calculus

    ERIC Educational Resources Information Center

    Berry, Andrew J.

    2007-01-01

    How might one define a functional operator D[superscript I]f(x), say for f(x) = 1 + x[superscript 2] + sin x, such that D[superscript +1](1 + x[superscript 2] + sin x) = 2x + cos x and D[superscript -1](1 + x[superscript 2] + sin x) = x + x[superscript 3]/3 - cos x? Our task in this article is to describe such an operator using a single formula…

  4. Disentangling the intragroup HI in Compact Groups of galaxies by means of X3D visualization

    NASA Astrophysics Data System (ADS)

    Verdes-Montenegro, Lourdes; Vogt, Frederic; Aubery, Claire; Duret, Laetitie; Garrido, Julián; Sánchez, Susana; Yun, Min S.; Borthakur, Sanchayeeta; Hess, Kelley; Cluver, Michelle; Del Olmo, Ascensión; Perea, Jaime

    2017-03-01

    As an extreme kind of environment, Hickson Compact groups (HCGs) have shown to be very complex systems. HI-VLA observations revealed an intrincated network of HI tails and bridges, tracing pre-processing through extreme tidal interactions. We found HCGs to show a large HI deficiency supporting an evolutionary sequence where gas-rich groups transform via tidal interactions and ISM (interstellar medium) stripping into gas-poor systems. We detected as well a diffuse HI component in the groups, increasing with evolutionary phase, although with uncertain distribution. The complex net of detected HI as observed with the VLA seems hence so puzzling as the missing one. In this talk we revisit the existing VLA information on the HI distribution and kinematics of HCGs by means of X3D visualization. X3D constitutes a powerful tool to extract the most from HI data cubes and a mean of simplifying and easing the access to data visualization and publication via three-dimensional (3-D) diagrams.

  5. Projection-slice theorem based 2D-3D registration

    NASA Astrophysics Data System (ADS)

    van der Bom, M. J.; Pluim, J. P. W.; Homan, R.; Timmer, J.; Bartels, L. W.

    2007-03-01

    In X-ray guided procedures, the surgeon or interventionalist is dependent on his or her knowledge of the patient's specific anatomy and the projection images acquired during the procedure by a rotational X-ray source. Unfortunately, these X-ray projections fail to give information on the patient's anatomy in the dimension along the projection axis. It would be very profitable to provide the surgeon or interventionalist with a 3D insight of the patient's anatomy that is directly linked to the X-ray images acquired during the procedure. In this paper we present a new robust 2D-3D registration method based on the Projection-Slice Theorem. This theorem gives us a relation between the pre-operative 3D data set and the interventional projection images. Registration is performed by minimizing a translation invariant similarity measure that is applied to the Fourier transforms of the images. The method was tested by performing multiple exhaustive searches on phantom data of the Circle of Willis and on a post-mortem human skull. Validation was performed visually by comparing the test projections to the ones that corresponded to the minimal value of the similarity measure. The Projection-Slice Theorem Based method was shown to be very effective and robust, and provides capture ranges up to 62 degrees. Experiments have shown that the method is capable of retrieving similar results when translations are applied to the projection images.

  6. The advantage of CT scans and 3D visualizations in the analysis of three child mummies from the Graeco-Roman Period.

    PubMed

    Villa, Chiara; Davey, Janet; Craig, Pamela J G; Drummer, Olaf H; Lynnerup, Niels

    2015-01-01

    Three child mummies from the Graeco-Roman Period (332 BCE - c. 395 CE) were examined using CT scans and 3D visualizations generated with Vitrea 2 and MIMICS graphic workstations with the aim of comparing the results with previous X-ray examinations performed by Dawson and Gray in 1968. Although the previous analyses reported that the children had been excerebrated and eviscerated, no evidence of incisions or breaches of the cranial cavity were found; 3D visualizations were generated showing the brain and the internal organs to be in situ. A larger number of skeletal post-mortem damages were identified, such as dislocation of mandible, ribs, and vertebrae, probably suffered at the time of embalming procedure. Different radio-opaque granular particles were observed throughout bodies (internally and externally) and could be explained as presence of natron, used as external desiccating agent by the embalmers, or as adipocerous alteration, a natural alteration of body fat. Age-at-death was estimated using the 3D visualization of the teeth, the state of fusion of the vertebrae and the presence of the secondary centers of the long bones: two mummies died at the age of 4 years ± 12 months, the third one at the age of 6 years ± 24 months. Hyperdontia or polydontia, a dental anomaly, could also be identified in one child using 3D visualizations of the teeth: two supernumerary teeth were found behind the maxillary permanent central incisors which had not been noticed in the Dawson and Gray's X-ray analysis. In conclusion, CT-scan investigations and especially 3D visualizations are important tools in the non-invasive analysis of the mummies and, in this case, provided revised and additional information compared to the only X-ray examination.

  7. [Computer-assisted operational planning for pediatric abdominal surgery. 3D-visualized MRI with volume rendering].

    PubMed

    Günther, P; Tröger, J; Holland-Cunz, S; Waag, K L; Schenk, J P

    2006-08-01

    Exact surgical planning is necessary for complex operations of pathological changes in anatomical structures of the pediatric abdomen. 3D visualization and computer-assisted operational planning based on CT data are being increasingly used for difficult operations in adults. To minimize radiation exposure and for better soft tissue contrast, sonography and MRI are the preferred diagnostic methods in pediatric patients. Because of manifold difficulties 3D visualization of these MRI data has not been realized so far, even though the field of embryonal malformations and tumors could benefit from this.A newly developed and modified raycasting-based powerful 3D volume rendering software (VG Studio Max 1.2) for the planning of pediatric abdominal surgery is presented. With the help of specifically developed algorithms, a useful surgical planning system is demonstrated. Thanks to the easy handling and high-quality visualization with enormous gain of information, the presented system is now an established part of routine surgical planning.

  8. Web-based three-dimensional geo-referenced visualization

    NASA Astrophysics Data System (ADS)

    Lin, Hui; Gong, Jianhua; Wang, Freeman

    1999-12-01

    This paper addresses several approaches to implementing web-based, three-dimensional (3-D), geo-referenced visualization. The discussion focuses on the relationship between multi-dimensional data sets and applications, as well as the thick/thin client and heavy/light server structure. Two models of data sets are addressed in this paper. One is the use of traditional 3-D data format such as 3-D Studio Max, Open Inventor 2.0, Vis5D and OBJ. The other is modelled by a web-based language such as VRML. Also, traditional languages such as C and C++, as well as web-based programming tools such as Java, Java3D and ActiveX, can be used for developing applications. The strengths and weaknesses of each approach are elaborated. Four practical solutions for using VRML and Java, Java and Java3D, VRML and ActiveX and Java wrapper classes (Java and C/C++), to develop applications are presented for web-based, real-time interactive and explorative visualization.

  9. Gamma/x-ray linear pushbroom stereo for 3D cargo inspection

    NASA Astrophysics Data System (ADS)

    Zhu, Zhigang; Hu, Yu-Chi

    2006-05-01

    For evaluating the contents of trucks, containers, cargo, and passenger vehicles by a non-intrusive gamma-ray or X-ray imaging system to determine the possible presence of contraband, three-dimensional (3D) measurements could provide more information than 2D measurements. In this paper, a linear pushbroom scanning model is built for such a commonly used gamma-ray or x-ray cargo inspection system. Accurate 3D measurements of the objects inside a cargo can be obtained by using two such scanning systems with different scanning angles to construct a pushbroom stereo system. A simple but robust calibration method is proposed to find the important parameters of the linear pushbroom sensors. Then, a fast and automated stereo matching algorithm based on free-form deformable registration is developed to obtain 3D measurements of the objects under inspection. A user interface is designed for 3D visualization of the objects in interests. Experimental results of sensor calibration, stereo matching, 3D measurements and visualization of a 3D cargo container and the objects inside, are presented.

  10. Planning, Implementation and Optimization of Future space Missions using an Immersive Visualization Environement (IVE) Machine

    NASA Astrophysics Data System (ADS)

    Harris, E.

    Planning, Implementation and Optimization of Future Space Missions using an Immersive Visualization Environment (IVE) Machine E. N. Harris, Lockheed Martin Space Systems, Denver, CO and George.W. Morgenthaler, U. of Colorado at Boulder History: A team of 3-D engineering visualization experts at the Lockheed Martin Space Systems Company have developed innovative virtual prototyping simulation solutions for ground processing and real-time visualization of design and planning of aerospace missions over the past 6 years. At the University of Colorado, a team of 3-D visualization experts are developing the science of 3-D visualization and immersive visualization at the newly founded BP Center for Visualization, which began operations in October, 2001. (See IAF/IAA-01-13.2.09, "The Use of 3-D Immersive Visualization Environments (IVEs) to Plan Space Missions," G. A. Dorn and G. W. Morgenthaler.) Progressing from Today's 3-D Engineering Simulations to Tomorrow's 3-D IVE Mission Planning, Simulation and Optimization Techniques: 3-D (IVEs) and visualization simulation tools can be combined for efficient planning and design engineering of future aerospace exploration and commercial missions. This technology is currently being developed and will be demonstrated by Lockheed Martin in the (IVE) at the BP Center using virtual simulation for clearance checks, collision detection, ergonomics and reach-ability analyses to develop fabrication and processing flows for spacecraft and launch vehicle ground support operations and to optimize mission architecture and vehicle design subject to realistic constraints. Demonstrations: Immediate aerospace applications to be demonstrated include developing streamlined processing flows for Reusable Space Transportation Systems and Atlas Launch Vehicle operations and Mars Polar Lander visual work instructions. Long-range goals include future international human and robotic space exploration missions such as the development of a Mars Reconnaissance Orbiter and Lunar Base construction scenarios. Innovative solutions utilizing Immersive Visualization provide the key to streamlining the mission planning and optimizing engineering design phases of future aerospace missions.

  11. Human factors guidelines for applications of 3D perspectives: a literature review

    NASA Astrophysics Data System (ADS)

    Dixon, Sharon; Fitzhugh, Elisabeth; Aleva, Denise

    2009-05-01

    Once considered too processing-intense for general utility, application of the third dimension to convey complex information is facilitated by the recent proliferation of technological advancements in computer processing, 3D displays, and 3D perspective (2.5D) renderings within a 2D medium. The profusion of complex and rapidly-changing dynamic information being conveyed in operational environments has elevated interest in possible military applications of 3D technologies. 3D can be a powerful mechanism for clearer information portrayal, facilitating rapid and accurate identification of key elements essential to mission performance and operator safety. However, implementation of 3D within legacy systems can be costly, making integration prohibitive. Therefore, identifying which tasks may benefit from 3D or 2.5D versus simple 2D visualizations is critical. Unfortunately, there is no "bible" of human factors guidelines for usability optimization of 2D, 2.5D, or 3D visualizations nor for determining which display best serves a particular application. Establishing such guidelines would provide an invaluable tool for designers and operators. Defining issues common to each will enhance design effectiveness. This paper presents the results of an extensive review of open source literature addressing 3D information displays, with particular emphasis on comparison of true 3D with 2D and 2.5D representations and their utility for military tasks. Seventy-five papers are summarized, highlighting militarily relevant applications of 3D visualizations and 2.5D perspective renderings. Based on these findings, human factors guidelines for when and how to use these visualizations, along with recommendations for further research are discussed.

  12. Rotational X-ray angiography: a method for intra-operative volume imaging of the left-atrium and pulmonary veins for atrial fibrillation ablation guidance

    NASA Astrophysics Data System (ADS)

    Manzke, R.; Zagorchev, L.; d'Avila, A.; Thiagalingam, A.; Reddy, V. Y.; Chan, R. C.

    2007-03-01

    Catheter-based ablation in the left atrium and pulmonary veins (LAPV) for treatment of atrial fibrillation in cardiac electrophysiology (EP) are complex and require knowledge of heart chamber anatomy. Electroanatomical mapping (EAM) is typically used to define cardiac structures by combining electromagnetic spatial catheter localization with surface models which interpolate the anatomy between EAM point locations in 3D. Recently, the incorporation of pre-operative volumetric CT or MR data sets has allowed for more detailed maps of LAPV anatomy to be used intra-operatively. Preoperative data sets are however a rough guide since they can be acquired several days to weeks prior to EP intervention. Due to positional and physiological changes, the intra-operative cardiac anatomy can be different from that depicted in the pre-operative data. We present an application of contrast-enhanced rotational X-ray imaging for CT-like reconstruction of 3D LAPV anatomy during the intervention itself. Depending on the heart size a single or two selective contrastenhanced rotational acquisitions are performed and CT-like volumes are reconstructed with 3D filtered back projection. In case of dual injection, the two volumes depicting the left and right portions of the LAPV are registered and fused. The data sets are visualized and segmented intra-procedurally to provide anatomical data and surface models for intervention guidance. Our results from animal and human experiments indicate that the anatomical information from intra-operative CT-like reconstructions compares favorably with preacquired imaging data and can be of sufficient quality for intra-operative guidance.

  13. 3D Visualization for Phoenix Mars Lander Science Operations

    NASA Technical Reports Server (NTRS)

    Edwards, Laurence; Keely, Leslie; Lees, David; Stoker, Carol

    2012-01-01

    Planetary surface exploration missions present considerable operational challenges in the form of substantial communication delays, limited communication windows, and limited communication bandwidth. A 3D visualization software was developed and delivered to the 2008 Phoenix Mars Lander (PML) mission. The components of the system include an interactive 3D visualization environment called Mercator, terrain reconstruction software called the Ames Stereo Pipeline, and a server providing distributed access to terrain models. The software was successfully utilized during the mission for science analysis, site understanding, and science operations activity planning. A terrain server was implemented that provided distribution of terrain models from a central repository to clients running the Mercator software. The Ames Stereo Pipeline generates accurate, high-resolution, texture-mapped, 3D terrain models from stereo image pairs. These terrain models can then be visualized within the Mercator environment. The central cross-cutting goal for these tools is to provide an easy-to-use, high-quality, full-featured visualization environment that enhances the mission science team s ability to develop low-risk productive science activity plans. In addition, for the Mercator and Viz visualization environments, extensibility and adaptability to different missions and application areas are key design goals.

  14. Managing Construction Operations Visually: 3-D Techniques for Complex Topography and Restricted Visibility

    ERIC Educational Resources Information Center

    Rodriguez, Walter; Opdenbosh, Augusto; Santamaria, Juan Carlos

    2006-01-01

    Visual information is vital in planning and managing construction operations, particularly, where there is complex terrain topography and salvage operations with limited accessibility and visibility. From visually-assessing site operations and preventing equipment collisions to simulating material handling activities to supervising remotes sites…

  15. Development of 3D ultrasound needle guidance for high-dose-rate interstitial brachytherapy of gynaecological cancers

    NASA Astrophysics Data System (ADS)

    Rodgers, J.; Tessier, D.; D'Souza, D.; Leung, E.; Hajdok, G.; Fenster, A.

    2016-04-01

    High-dose-rate (HDR) interstitial brachytherapy is often included in standard-of-care for gynaecological cancers. Needles are currently inserted through a perineal template without any standard real-time imaging modality to assist needle guidance, causing physicians to rely on pre-operative imaging, clinical examination, and experience. While two-dimensional (2D) ultrasound (US) is sometimes used for real-time guidance, visualization of needle placement and depth is difficult and subject to variability and inaccuracy in 2D images. The close proximity to critical organs, in particular the rectum and bladder, can lead to serious complications. We have developed a three-dimensional (3D) transrectal US system and are investigating its use for intra-operative visualization of needle positions used in HDR gynaecological brachytherapy. As a proof-of-concept, four patients were imaged with post-insertion 3D US and x-ray CT. Using software developed in our laboratory, manual rigid registration of the two modalities was performed based on the perineal template's vaginal cylinder. The needle tip and a second point along the needle path were identified for each needle visible in US. The difference between modalities in the needle trajectory and needle tip position was calculated for each identified needle. For the 60 needles placed, the mean trajectory difference was 3.23 +/- 1.65° across the 53 visible needle paths and the mean difference in needle tip position was 3.89 +/- 1.92 mm across the 48 visible needles tips. Based on the preliminary results, 3D transrectal US shows potential for the development of a 3D US-based needle guidance system for interstitial gynaecological brachytherapy.

  16. Applying microCT and 3D visualization to Jurassic silicified conifer seed cones: A virtual advantage over thin-sectioning.

    PubMed

    Gee, Carole T

    2013-11-01

    As an alternative to conventional thin-sectioning, which destroys fossil material, high-resolution X-ray computed tomography (also called microtomography or microCT) integrated with scientific visualization, three-dimensional (3D) image segmentation, size analysis, and computer animation is explored as a nondestructive method of imaging the internal anatomy of 150-million-year-old conifer seed cones from the Late Jurassic Morrison Formation, USA, and of recent and other fossil cones. • MicroCT was carried out on cones using a General Electric phoenix v|tome|x s 240D, and resulting projections were processed with visualization software to produce image stacks of serial single sections for two-dimensional (2D) visualization, 3D segmented reconstructions with targeted structures in color, and computer animations. • If preserved in differing densities, microCT produced images of internal fossil tissues that showed important characters such as seed phyllotaxy or number of seeds per cone scale. Color segmentation of deeply embedded seeds highlighted the arrangement of seeds in spirals. MicroCT of recent cones was even more effective. • This is the first paper on microCT integrated with 3D segmentation and computer animation applied to silicified seed cones, which resulted in excellent 2D serial sections and segmented 3D reconstructions, revealing features requisite to cone identification and understanding of strobilus construction.

  17. Virtual finger boosts three-dimensional imaging and microsurgery as well as terabyte volume image visualization and analysis.

    PubMed

    Peng, Hanchuan; Tang, Jianyong; Xiao, Hang; Bria, Alessandro; Zhou, Jianlong; Butler, Victoria; Zhou, Zhi; Gonzalez-Bellido, Paloma T; Oh, Seung W; Chen, Jichao; Mitra, Ananya; Tsien, Richard W; Zeng, Hongkui; Ascoli, Giorgio A; Iannello, Giulio; Hawrylycz, Michael; Myers, Eugene; Long, Fuhui

    2014-07-11

    Three-dimensional (3D) bioimaging, visualization and data analysis are in strong need of powerful 3D exploration techniques. We develop virtual finger (VF) to generate 3D curves, points and regions-of-interest in the 3D space of a volumetric image with a single finger operation, such as a computer mouse stroke, or click or zoom from the 2D-projection plane of an image as visualized with a computer. VF provides efficient methods for acquisition, visualization and analysis of 3D images for roundworm, fruitfly, dragonfly, mouse, rat and human. Specifically, VF enables instant 3D optical zoom-in imaging, 3D free-form optical microsurgery, and 3D visualization and annotation of terabytes of whole-brain image volumes. VF also leads to orders of magnitude better efficiency of automated 3D reconstruction of neurons and similar biostructures over our previous systems. We use VF to generate from images of 1,107 Drosophila GAL4 lines a projectome of a Drosophila brain.

  18. 1000 X difference between current displays and capability of human visual system: payoff potential for affordable defense systems

    NASA Astrophysics Data System (ADS)

    Hopper, Darrel G.

    2000-08-01

    Displays were invented just in the last century. The human visual system evolved over millions of years. The disparity between the natural world 'display' and that 'sampled' by year 2000 technology is more than a factor of one million. Over 1000X of this disparity between the fidelity of current electronic displays and human visual capacity is in 2D resolution alone. Then there is true 3D, which adds an additional factor of over 1000X. The present paper focuses just on the 2D portion of this grand technology challenge. Should a significant portion of this gap be closed, say just 10X by 2010, display technology can help drive a revolution in military affairs. Warfighter productivity must grow dramatically, and improved display technology systems can create a critical opportunity to increase defense capability while decreasing crew sizes.

  19. Micro-CT images reconstruction and 3D visualization for small animal studying

    NASA Astrophysics Data System (ADS)

    Gong, Hui; Liu, Qian; Zhong, Aijun; Ju, Shan; Fang, Quan; Fang, Zheng

    2005-01-01

    A small-animal x-ray micro computed tomography (micro-CT) system has been constructed to screen laboratory small animals and organs. The micro-CT system consists of dual fiber-optic taper-coupled CCD detectors with a field-of-view of 25x50 mm2, a microfocus x-ray source, a rotational subject holder. For accurate localization of rotation center, coincidence between the axis of rotation and centre of image was studied by calibration with a polymethylmethacrylate cylinder. Feldkamp"s filtered back-projection cone-beam algorithm is adopted for three-dimensional reconstruction on account of the effective corn-beam angle is 5.67° of the micro-CT system. 200x1024x1024 matrix data of micro-CT is obtained with the magnification of 1.77 and pixel size of 31x31μm2. In our reconstruction software, output image size of micro-CT slices data, magnification factor and rotation sample degree can be modified in the condition of different computational efficiency and reconstruction region. The reconstructed image matrix data is processed and visualization by Visualization Toolkit (VTK). Data parallelism of VTK is performed in surface rendering of reconstructed data in order to improve computing speed. Computing time of processing a 512x512x512 matrix datasets is about 1/20 compared with serial program when 30 CPU is used. The voxel size is 54x54x108 μm3. The reconstruction and 3-D visualization images of laboratory rat ear are presented.

  20. Tomo-PIV measurements of the flow field in the wake of a sphere

    NASA Astrophysics Data System (ADS)

    Eshbal, Lior; David, Tom; Rinsky, Vladislav; van Hout, Rene; Greenblatt, David

    2017-11-01

    A sphere can be considered as a prototypical 3D bluff body. In order to improve our understanding of its 3D wake flow, a combination of time-resolved planar particle image velocimetry (PIV) and tomographic PIV (tomo-PIV) was implemented. Experiments were performed in a closed-loop water channel facility and sphere Reynolds numbers ReD = UD/ ν = 400, 800, 1200 and 2000, where U is the free-stream velocity, ν the kinematic viscosity and D the sphere diameter. The measurement volume (Height x Length x Width, 5 x 5 x 1.5 D3) comprised the sphere and the downstream wake. Tomo-PIV snap-shots were correlated with the time-resolved PIV such that the 3D temporal evolution of the shed vortices became clear. At ReD = 400, this procedure revealed shed hairpin vortices having a vertical plane of symmetry in agreement with many dye visualization studies. However, the measurements also revealed weaker induced hairpins resulting from the interaction of the near-wake flow and the surrounding free stream. These induced vortices were not visible in previous dye and smoke visualizations and have only been observed in simulations. Data processing of the data at higher ReD is currently ongoing. Israel Science Foundation Grant No. 1596/14.

  1. Cognitive Aspects of Collaboration in 3d Virtual Environments

    NASA Astrophysics Data System (ADS)

    Juřík, V.; Herman, L.; Kubíček, P.; Stachoň, Z.; Šašinka, Č.

    2016-06-01

    Human-computer interaction has entered the 3D era. The most important models representing spatial information — maps — are transferred into 3D versions regarding the specific content to be displayed. Virtual worlds (VW) become promising area of interest because of possibility to dynamically modify content and multi-user cooperation when solving tasks regardless to physical presence. They can be used for sharing and elaborating information via virtual images or avatars. Attractiveness of VWs is emphasized also by possibility to measure operators' actions and complex strategies. Collaboration in 3D environments is the crucial issue in many areas where the visualizations are important for the group cooperation. Within the specific 3D user interface the operators' ability to manipulate the displayed content is explored regarding such phenomena as situation awareness, cognitive workload and human error. For such purpose, the VWs offer a great number of tools for measuring the operators' responses as recording virtual movement or spots of interest in the visual field. Study focuses on the methodological issues of measuring the usability of 3D VWs and comparing them with the existing principles of 2D maps. We explore operators' strategies to reach and interpret information regarding the specific type of visualization and different level of immersion.

  2. In situ flash x-ray high-speed computed tomography for the quantitative analysis of highly dynamic processes

    NASA Astrophysics Data System (ADS)

    Moser, Stefan; Nau, Siegfried; Salk, Manfred; Thoma, Klaus

    2014-02-01

    The in situ investigation of dynamic events, ranging from car crash to ballistics, often is key to the understanding of dynamic material behavior. In many cases the important processes and interactions happen on the scale of milli- to microseconds at speeds of 1000 m s-1 or more. Often, 3D information is necessary to fully capture and analyze all relevant effects. High-speed 3D-visualization techniques are thus required for the in situ analysis. 3D-capable optical high-speed methods often are impaired by luminous effects and dust, while flash x-ray based methods usually deliver only 2D data. In this paper, a novel 3D-capable flash x-ray based method, in situ flash x-ray high-speed computed tomography is presented. The method is capable of producing 3D reconstructions of high-speed processes based on an undersampled dataset consisting of only a few (typically 3 to 6) x-ray projections. The major challenges are identified, discussed and the chosen solution outlined. The application is illustrated with an exemplary application of a 1000 m s-1 high-speed impact event on the scale of microseconds. A quantitative analysis of the in situ measurement of the material fragments with a 3D reconstruction with 1 mm voxel size is presented and the results are discussed. The results show that the HSCT method allows gaining valuable visual and quantitative mechanical information for the understanding and interpretation of high-speed events.

  3. FoxP2 is a Parvocellular-Specific Transcription Factor in the Visual Thalamus of Monkeys and Ferrets

    PubMed Central

    Iwai, Lena; Ohashi, Yohei; van der List, Deborah; Usrey, William Martin; Miyashita, Yasushi; Kawasaki, Hiroshi

    2013-01-01

    Although the parallel visual pathways are a fundamental basis of visual processing, our knowledge of their molecular properties is still limited. Here, we uncovered a parvocellular-specific molecule in the dorsal lateral geniculate nucleus (dLGN) of higher mammals. We found that FoxP2 transcription factor was specifically expressed in X cells of the adult ferret dLGN. Interestingly, FoxP2 was also specifically expressed in parvocellular layers 3–6 of the dLGN of adult old world monkeys, providing new evidence for a homology between X cells in the ferret dLGN and parvocellular cells in the monkey dLGN. Furthermore, this expression pattern was established as early as gestation day 140 in the embryonic monkey dLGN, suggesting that parvocellular specification has already occurred when the cytoarchitectonic dLGN layers are formed. Our results should help in gaining a fundamental understanding of the development, evolution, and function of the parallel visual pathways, which are especially prominent in higher mammals. PMID:22791804

  4. In vivo three-dimensional confocal laser scanning microscopy of the epithelial nerve structure in the human cornea.

    PubMed

    Stachs, Oliver; Zhivov, Andrey; Kraak, Robert; Stave, Joachim; Guthoff, Rudolf

    2007-04-01

    Evaluation of a new method for in vivo visualization of the distribution and morphology of human anterior corneal nerves. The anterior cornea was examined to a depth of 100 microm in four human volunteers with a confocal laser scanning microscope (CLSM) using a Rostock Cornea Module (developed in house) attached to a Heidelberg Retina Tomograph II (Heidelberg Engineering, Germany). Optical sections were digitally reconstructed in 3D using AMIRA (TGS Inc., USA). The scanned volumes had a greatest size of 300 x 300 x 40 microm and voxel size of 0.78 x 0.78 x 0.95 microm. The spatial arrangement of the epithelium, nerves and keratocytes was visualized by in vivo 3D-CLSM. The 3D-reconstruction of the volunteers' corneas in combination with the oblique sections gave a picture of the nerves in the central human cornea. Thin nerves run in the subepithelial plexus aligned parallel to Bowman's layer and are partially interconnected. The diameter of these fibres varied between 1.0 and 5 microm. Thick fibres rose out of the deeper stroma. The diameter of the main nerve trunks was 12+/-2 microm. Branches penetrating the anterior epithelial cell layer could not be visualized. 3D-CLSM allows analysis of the spatial arrangement of the anterior corneal nerves and visualization of the epithelium and keratocytes in the living human cornea. The developed method provides a basis for further studies of alterations of the cellular arrangement and epithelial innervation in corneal disease. This may help to clarify alterations of nerve fibre patterns under various clinical and experimental conditions.

  5. The viewpoint-specific failure of modern 3D displays in laparoscopic surgery.

    PubMed

    Sakata, Shinichiro; Grove, Philip M; Hill, Andrew; Watson, Marcus O; Stevenson, Andrew R L

    2016-11-01

    Surgeons conventionally assume the optimal viewing position during 3D laparoscopic surgery and may not be aware of the potential hazards to team members positioned across different suboptimal viewing positions. The first aim of this study was to map the viewing positions within a standard operating theatre where individuals may experience visual ghosting (i.e. double vision images) from crosstalk. The second aim was to characterize the standard viewing positions adopted by instrument nurses and surgical assistants during laparoscopic pelvic surgery and report the associated levels of visual ghosting and discomfort. In experiment 1, 15 participants viewed a laparoscopic 3D display from 176 different viewing positions around the screen. In experiment 2, 12 participants (randomly assigned to four clinically relevant viewing positions) viewed laparoscopic suturing in a simulation laboratory. In both experiments, we measured the intensity of visual ghosting. In experiment 2, participants also completed the Simulator Sickness Questionnaire. We mapped locations within the dimensions of a standard operating theatre at which visual ghosting may result during 3D laparoscopy. Head height relative to the bottom of the image and large horizontal eccentricities away from the surface normal were important contributors to high levels of visual ghosting. Conventional viewing positions adopted by instrument nurses yielded high levels of visual ghosting and severe discomfort. The conventional viewing positions adopted by surgical team members during laparoscopic pelvic operations are suboptimal for viewing 3D laparoscopic displays, and even short periods of viewing can yield high levels of discomfort.

  6. Development of a 3-D X-ray system

    NASA Astrophysics Data System (ADS)

    Evans, James Paul Owain

    The interpretation of standard two-dimensional x-ray images by humans is often very difficult. This is due to the lack of visual cues to depth in an image which has been produced by transmitted radiation. The solution put forward in this research is to introduce binocular parallax, a powerful physiological depth cue, into the resultant shadowgraph x-ray image. This has been achieved by developing a binocular stereoscopic x-ray imaging technique, which can be used for both visual inspection by human observers and also for the extraction of three-dimensional co-ordinate information. The technique is implemented in the design and development of two experimental x-ray systems and also the development of measurement algorithms. The first experimental machine is based on standard linear x-ray detector arrays and was designed as an optimum configuration for visual inspection by human observers. However, it was felt that a combination of the 3-D visual inspection capability together with a measurement facility would enhance the usefulness of the technique. Therefore, both a theoretical and an empirical analysis of the co-ordinate measurement capability of the machine has been carried out. The measurement is based on close-range photogrammetric techniques. The accuracy of the measurement has been found to be of the order of 4mm in x, 3mm in y and 6mm in z. A second experimental machine was developed and based on the same technique as that used for the first machine. However, a major departure has been the introduction of a dual energy linear x-ray detector array which will allow, in general, the discrimination between organic and inorganic substances. The second design is a compromise between ease of visual inspection for human observers and optimum three-dimensional co-ordinate measurement capability. The system is part of an on going research programme into the possibility of introducing psychological depth cues into the resultant x-ray images. The research presented in this thesis was initiated to enhance the visual interpretation of complex x-ray images, specifically in response to problems encountered in the routine screening of freight by HM. Customs and Excise. This phase of the work culminated in the development of the first experimental machine. During this work the security industry was starting to adopt a new type of x-ray detector, namely the dual energy x-ray sensor. The Department of Transport made available funding to the Police Scientific Development Branch (P.S.D.B.), part of The Home Office Science and Technology Group, to investigate the possibility of utilising the dual energy sensor in a 3-D x-ray screening system. This phase of the work culminated in the development of the second experimental machine.

  7. Integrated Web-Based Immersive Exploration of the Coordinated Canyon Experiment Data using Open Source STOQS Software

    NASA Astrophysics Data System (ADS)

    McCann, M. P.; Gwiazda, R.; O'Reilly, T. C.; Maier, K. L.; Lundsten, E. M.; Parsons, D. R.; Paull, C. K.

    2017-12-01

    The Coordinated Canyon Experiment (CCE) in Monterey Submarine Canyon has produced a wealth of oceanographic measurements whose analysis will improve understanding of turbidity current processes. Exploration of this data set, consisting of over 60 parameters from 15 platforms, is facilitated by using the open source Spatial Temporal Oceanographic Query System (STOQS) software (https://github.com/stoqs/stoqs). The Monterey Bay Aquarium Research Institute (MBARI) originally developed STOQS to help manage and visualize upper water column oceanographic measurements, but the generality of its data model permits effective use for any kind of spatial/temporal measurement data. STOQS consists of a PostgreSQL database and server-side Python/Django software; the client-side is jQuery JavaScript supporting AJAX requests to update a single page web application. The User Interface (UI) is optimized to provide a quick overview of data in spatial and temporal dimensions, as well as in parameter, platform, and data value space. A user may zoom into any feature of interest and select it, initiating a filter operation that updates the UI with an overview of all the data in the new filtered selection. When details are desired, radio buttons and checkboxes are selected to generate a number of different types of visualizations. These include color-filled temporal section and line plots, parameter-parameter plots, 2D map plots, and interactive 3D spatial visualizations. The Extensible 3D (X3D) standard and X3DOM JavaScript library provide the technology for presenting animated 3D data directly within the web browser. Most of the oceanographic measurements from the CCE (e.g. mooring mounted ADCP and CTD data) are easily visualized using established methods. However, unified integration and multiparameter display of several concurrently deployed sensors across a network of platforms is a challenge we hope to solve. Moreover, STOQS also allows display of data from a new instrument - the Benthic Event Detector (BED). The BED records 50Hz samples of orientation and acceleration when it moves. These data are converted to the CF-NetCDF format and then loaded into a STOQS database. Using the Spatial-3D view a user may interact with a virtual playback of BED motions, giving new insight into submarine canyon sediment density flows.

  8. High-Performance 3D Articulated Robot Display

    NASA Technical Reports Server (NTRS)

    Powell, Mark W.; Torres, Recaredo J.; Mittman, David S.; Kurien, James A.; Abramyan, Lucy

    2011-01-01

    In the domain of telerobotic operations, the primary challenge facing the operator is to understand the state of the robotic platform. One key aspect of understanding the state is to visualize the physical location and configuration of the platform. As there is a wide variety of mobile robots, the requirements for visualizing their configurations vary diversely across different platforms. There can also be diversity in the mechanical mobility, such as wheeled, tracked, or legged mobility over surfaces. Adaptable 3D articulated robot visualization software can accommodate a wide variety of robotic platforms and environments. The visualization has been used for surface, aerial, space, and water robotic vehicle visualization during field testing. It has been used to enable operations of wheeled and legged surface vehicles, and can be readily adapted to facilitate other mechanical mobility solutions. The 3D visualization can render an articulated 3D model of a robotic platform for any environment. Given the model, the software receives real-time telemetry from the avionics system onboard the vehicle and animates the robot visualization to reflect the telemetered physical state. This is used to track the position and attitude in real time to monitor the progress of the vehicle as it traverses its environment. It is also used to monitor the state of any or all articulated elements of the vehicle, such as arms, legs, or control surfaces. The visualization can also render other sorts of telemetered states visually, such as stress or strains that are measured by the avionics. Such data can be used to color or annotate the virtual vehicle to indicate nominal or off-nominal states during operation. The visualization is also able to render the simulated environment where the vehicle is operating. For surface and aerial vehicles, it can render the terrain under the vehicle as the avionics sends it location information (GPS, odometry, or star tracking), and locate the vehicle over or on the terrain correctly. For long traverses over terrain, the visualization can stream in terrain piecewise in order to maintain the current area of interest for the operator without incurring unreasonable resource constraints on the computing platform. The visualization software is designed to run on laptops that can operate in field-testing environments without Internet access, which is a frequently encountered situation when testing in remote locations that simulate planetary environments such as Mars and other planetary bodies.

  9. The effect of mitomycin C trabeculectomy on the progression of visual field defect in normal-tension glaucoma.

    PubMed

    Hagiwara, Y; Yamamoto, T; Kitazawa, Y

    2000-03-01

    We investigated in a prospective fashion the visual prognosis and complications in normal-tension glaucoma following unilateral trabeculectomy with adjunctive mitomycin C. Trabeculectomy with adjunctive mitomycin C was carried out unilaterally in 21 cases of normal-tension glaucoma. Intraocular pressure (IOP), visual prognosis, and complications were compared between the operated eyes and the non-operated fellow eyes. The follow-up period ranged from 2 to 7 years. The IOP dropped significantly from 14.8+/-1.8 mmHg (mean +/- SD) to 9.6+/-3.9 mmHg in the operated eyes (P=0.0002, Wilcoxon signed-rank test), but did not drop in the non-operated eyes. The mean deviation (MD) was -12.69+/-6.41 dB preoperatively and -14.70+/-5.49 dB at the last clinic visit in the operated eyes, whereas in non-operated eyes it was -7.85+/-5.65 dB and -11.15+/-5.62 dB, respectively. The MD deteriorated significantly in both operated and non-operated eyes (operated eyes P=0.0239, non-operated eyes: P=0.0002; Wilcoxon signed-rank test). The MD slope was -0.37+/-0.60 dB/year and -0.71+/-0.89 dB/year for the operated and non-operated eyes, respectively (P=0.5243, Mann-Whitney U-test). Visual field deterioration was more frequently observed in the non-operated eyes by a pointwise definition of the progression (P<0.05, McNemar test). Visual acuity deteriorated in 6 of the operated eyes and in 5 of the non-operated eyes. Cataract developed in 6 (29%) of the 21 operated eyes, while among the non-operated eyes 4 (19%) developed cataract. Mitomycin C trabeculectomy is effective in delaying progression of visual field defect in normal-tension glaucoma, but complications may arise and cause some visual disturbance.

  10. Applying microCT and 3D visualization to Jurassic silicified conifer seed cones: A virtual advantage over thin-sectioning1

    PubMed Central

    Gee, Carole T.

    2013-01-01

    • Premise of the study: As an alternative to conventional thin-sectioning, which destroys fossil material, high-resolution X-ray computed tomography (also called microtomography or microCT) integrated with scientific visualization, three-dimensional (3D) image segmentation, size analysis, and computer animation is explored as a nondestructive method of imaging the internal anatomy of 150-million-year-old conifer seed cones from the Late Jurassic Morrison Formation, USA, and of recent and other fossil cones. • Methods: MicroCT was carried out on cones using a General Electric phoenix v|tome|x s 240D, and resulting projections were processed with visualization software to produce image stacks of serial single sections for two-dimensional (2D) visualization, 3D segmented reconstructions with targeted structures in color, and computer animations. • Results: If preserved in differing densities, microCT produced images of internal fossil tissues that showed important characters such as seed phyllotaxy or number of seeds per cone scale. Color segmentation of deeply embedded seeds highlighted the arrangement of seeds in spirals. MicroCT of recent cones was even more effective. • Conclusions: This is the first paper on microCT integrated with 3D segmentation and computer animation applied to silicified seed cones, which resulted in excellent 2D serial sections and segmented 3D reconstructions, revealing features requisite to cone identification and understanding of strobilus construction. PMID:25202495

  11. Unimpeded permeation of water through biocidal graphene oxide sheets anchored on to 3D porous polyolefinic membranes.

    PubMed

    Mural, Prasanna Kumar S; Jain, Shubham; Kumar, Sachin; Madras, Giridhar; Bose, Suryasarathi

    2016-04-21

    3D porous membranes were developed by etching one of the phases (here PEO, polyethylene oxide) from melt-mixed PE/PEO binary blends. Herein, we have systematically discussed the development of these membranes using X-ray micro-computed tomography. The 3D tomograms of the extruded strands and hot-pressed samples revealed a clear picture as to how the morphology develops and coarsens over a function of time during post-processing operations like compression molding. The coarsening of PE/PEO blends was traced using X-ray micro-computed tomography and scanning electron microscopy (SEM) of annealed blends at different times. It is now understood from X-ray micro-computed tomography that by the addition of a compatibilizer (here lightly maleated PE), a stable morphology can be visualized in 3D. In order to anchor biocidal graphene oxide sheets onto these 3D porous membranes, the PE membranes were chemically modified with acid/ethylene diamine treatment to anchor the GO sheets which were further confirmed by Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and surface Raman mapping. The transport properties through the membrane clearly reveal unimpeded permeation of water which suggests that anchoring GO on to the membranes does not clog the pores. Antibacterial studies through the direct contact of bacteria with GO anchored PE membranes resulted in 99% of bacterial inactivation. The possible bacterial inactivation through physical disruption of the bacterial cell wall and/or reactive oxygen species (ROS) is discussed herein. Thus this study opens new avenues in designing polyolefin based antibacterial 3D porous membranes for water purification.

  12. Reusable science tools for analog exploration missions: xGDS Web Tools, VERVE, and Gigapan Voyage

    NASA Astrophysics Data System (ADS)

    Lee, Susan Y.; Lees, David; Cohen, Tamar; Allan, Mark; Deans, Matthew; Morse, Theodore; Park, Eric; Smith, Trey

    2013-10-01

    The Exploration Ground Data Systems (xGDS) project led by the Intelligent Robotics Group (IRG) at NASA Ames Research Center creates software tools to support multiple NASA-led planetary analog field experiments. The two primary tools that fall under the xGDS umbrella are the xGDS Web Tools (xGDS-WT) and Visual Environment for Remote Virtual Exploration (VERVE). IRG has also developed a hardware and software system that is closely integrated with our xGDS tools and is used in multiple field experiments called Gigapan Voyage. xGDS-WT, VERVE, and Gigapan Voyage are examples of IRG projects that improve the ratio of science return versus development effort by creating generic and reusable tools that leverage existing technologies in both hardware and software. xGDS Web Tools provides software for gathering and organizing mission data for science and engineering operations, including tools for planning traverses, monitoring autonomous or piloted vehicles, visualization, documentation, analysis, and search. VERVE provides high performance three dimensional (3D) user interfaces used by scientists, robot operators, and mission planners to visualize robot data in real time. Gigapan Voyage is a gigapixel image capturing and processing tool that improves situational awareness and scientific exploration in human and robotic analog missions. All of these technologies emphasize software reuse and leverage open source and/or commercial-off-the-shelf tools to greatly improve the utility and reduce the development and operational cost of future similar technologies. Over the past several years these technologies have been used in many NASA-led robotic field campaigns including the Desert Research and Technology Studies (DRATS), the Pavilion Lake Research Project (PLRP), the K10 Robotic Follow-Up tests, and most recently we have become involved in the NASA Extreme Environment Mission Operations (NEEMO) field experiments. A major objective of these joint robot and crew experiments is to improve NASAs understanding of how to most effectively execute and increase science return from exploration missions. This paper focuses on an integrated suite of xGDS software and compatible hardware tools: xGDS Web Tools, VERVE, and Gigapan Voyage, how they are used, and the design decisions that were made to allow them to be easily developed, integrated, tested, and reused by multiple NASA field experiments and robotic platforms.

  13. Planning, implementation and optimization of future space missions using an immersive visualization environment (IVE) machine

    NASA Astrophysics Data System (ADS)

    Nathan Harris, E.; Morgenthaler, George W.

    2004-07-01

    Beginning in 1995, a team of 3-D engineering visualization experts assembled at the Lockheed Martin Space Systems Company and began to develop innovative virtual prototyping simulation tools for performing ground processing and real-time visualization of design and planning of aerospace missions. At the University of Colorado, a team of 3-D visualization experts also began developing the science of 3-D visualization and immersive visualization at the newly founded British Petroleum (BP) Center for visualization, which began operations in October, 2001. BP acquired ARCO in the year 2000 and awarded the 3-D flexible IVE developed by ARCO (beginning in 1990) to the University of Colorado, CU, the winner in a competition among 6 Universities. CU then hired Dr. G. Dorn, the leader of the ARCO team as Center Director, and the other experts to apply 3-D immersive visualization to aerospace and to other University Research fields, while continuing research on surface interpretation of seismic data and 3-D volumes. This paper recounts further progress and outlines plans in Aerospace applications at Lockheed Martin and CU.

  14. Visually impaired researchers get their hands on quantum chemistry: application to a computational study on the isomerization of a sterol.

    PubMed

    Lounnas, Valère; Wedler, Henry B; Newman, Timothy; Schaftenaar, Gijs; Harrison, Jason G; Nepomuceno, Gabriella; Pemberton, Ryan; Tantillo, Dean J; Vriend, Gert

    2014-11-01

    In molecular sciences, articles tend to revolve around 2D representations of 3D molecules, and sighted scientists often resort to 3D virtual reality software to study these molecules in detail. Blind and visually impaired (BVI) molecular scientists have access to a series of audio devices that can help them read the text in articles and work with computers. Reading articles published in this journal, though, is nearly impossible for them because they need to generate mental 3D images of molecules, but the article-reading software cannot do that for them. We have previously designed AsteriX, a web server that fully automatically decomposes articles, detects 2D plots of low molecular weight molecules, removes meta data and annotations from these plots, and converts them into 3D atomic coordinates. AsteriX-BVI goes one step further and converts the 3D representation into a 3D printable, haptic-enhanced format that includes Braille annotations. These Braille-annotated physical 3D models allow BVI scientists to generate a complete mental model of the molecule. AsteriX-BVI uses Molden to convert the meta data of quantum chemistry experiments into BVI friendly formats so that the entire line of scientific information that sighted people take for granted-from published articles, via printed results of computational chemistry experiments, to 3D models-is now available to BVI scientists too. The possibilities offered by AsteriX-BVI are illustrated by a project on the isomerization of a sterol, executed by the blind co-author of this article (HBW).

  15. Visually impaired researchers get their hands on quantum chemistry: application to a computational study on the isomerization of a sterol

    NASA Astrophysics Data System (ADS)

    Lounnas, Valère; Wedler, Henry B.; Newman, Timothy; Schaftenaar, Gijs; Harrison, Jason G.; Nepomuceno, Gabriella; Pemberton, Ryan; Tantillo, Dean J.; Vriend, Gert

    2014-11-01

    In molecular sciences, articles tend to revolve around 2D representations of 3D molecules, and sighted scientists often resort to 3D virtual reality software to study these molecules in detail. Blind and visually impaired (BVI) molecular scientists have access to a series of audio devices that can help them read the text in articles and work with computers. Reading articles published in this journal, though, is nearly impossible for them because they need to generate mental 3D images of molecules, but the article-reading software cannot do that for them. We have previously designed AsteriX, a web server that fully automatically decomposes articles, detects 2D plots of low molecular weight molecules, removes meta data and annotations from these plots, and converts them into 3D atomic coordinates. AsteriX-BVI goes one step further and converts the 3D representation into a 3D printable, haptic-enhanced format that includes Braille annotations. These Braille-annotated physical 3D models allow BVI scientists to generate a complete mental model of the molecule. AsteriX-BVI uses Molden to convert the meta data of quantum chemistry experiments into BVI friendly formats so that the entire line of scientific information that sighted people take for granted—from published articles, via printed results of computational chemistry experiments, to 3D models—is now available to BVI scientists too. The possibilities offered by AsteriX-BVI are illustrated by a project on the isomerization of a sterol, executed by the blind co-author of this article (HBW).

  16. Pre- and postprocessing techniques for determining goodness of computational meshes

    NASA Technical Reports Server (NTRS)

    Oden, J. Tinsley; Westermann, T.; Bass, J. M.

    1993-01-01

    Research in error estimation, mesh conditioning, and solution enhancement for finite element, finite difference, and finite volume methods has been incorporated into AUDITOR, a modern, user-friendly code, which operates on 2D and 3D unstructured neutral files to improve the accuracy and reliability of computational results. Residual error estimation capabilities provide local and global estimates of solution error in the energy norm. Higher order results for derived quantities may be extracted from initial solutions. Within the X-MOTIF graphical user interface, extensive visualization capabilities support critical evaluation of results in linear elasticity, steady state heat transfer, and both compressible and incompressible fluid dynamics.

  17. JWFront: Wavefronts and Light Cones for Kerr Spacetimes

    NASA Astrophysics Data System (ADS)

    Frutos Alfaro, Francisco; Grave, Frank; Müller, Thomas; Adis, Daria

    2015-04-01

    JWFront visualizes wavefronts and light cones in general relativity. The interactive front-end allows users to enter the initial position values and choose the values for mass and angular momentum per unit mass. The wavefront animations are available in 2D and 3D; the light cones are visualized using the coordinate systems (t, x, y) or (t, z, x). JWFront can be easily modified to simulate wavefronts and light cones for other spacetime by providing the Christoffel symbols in the program.

  18. Extremely Low Operating Current Resistive Memory Based on Exfoliated 2D Perovskite Single Crystals for Neuromorphic Computing.

    PubMed

    Tian, He; Zhao, Lianfeng; Wang, Xuefeng; Yeh, Yao-Wen; Yao, Nan; Rand, Barry P; Ren, Tian-Ling

    2017-12-26

    Extremely low energy consumption neuromorphic computing is required to achieve massively parallel information processing on par with the human brain. To achieve this goal, resistive memories based on materials with ionic transport and extremely low operating current are required. Extremely low operating current allows for low power operation by minimizing the program, erase, and read currents. However, materials currently used in resistive memories, such as defective HfO x , AlO x , TaO x , etc., cannot suppress electronic transport (i.e., leakage current) while allowing good ionic transport. Here, we show that 2D Ruddlesden-Popper phase hybrid lead bromide perovskite single crystals are promising materials for low operating current nanodevice applications because of their mixed electronic and ionic transport and ease of fabrication. Ionic transport in the exfoliated 2D perovskite layer is evident via the migration of bromide ions. Filaments with a diameter of approximately 20 nm are visualized, and resistive memories with extremely low program current down to 10 pA are achieved, a value at least 1 order of magnitude lower than conventional materials. The ionic migration and diffusion as an artificial synapse is realized in the 2D layered perovskites at the pA level, which can enable extremely low energy neuromorphic computing.

  19. High-resolution x-ray tomography using laboratory sources

    NASA Astrophysics Data System (ADS)

    Tkachuk, Andrei; Feser, Michael; Cui, Hongtao; Duewer, Fred; Chang, Hauyee; Yun, Wenbing

    2006-08-01

    X-ray computed tomography (XCT) is a powerful nondestructive 3D imaging technique, which enables the visualization of the three dimensional structure of complex, optically opaque samples. High resolution XCT using Fresnel zone plate lenses has been confined in the past to synchrotron radiation centers due to the need for a bright and intense source of x-rays. This confinement severely limits the availability and accessibility of x-ray microscopes and the wide proliferation of this methodology. We are describing a sub-50nm resolution XCT system operating at 8 keV in absorption and Zernike phase contrast mode based on a commercially available laboratory x-ray source. The system utilizes high-efficiency Fresnel zone plates with an outermost zone width of 35 nm and 700 nm structure height resulting in a current spatial resolution better than 50 nm. In addition to the technical description of the system and specifications, we present application examples in the semiconductor field.

  20. View-Based Models of 3D Object Recognition and Class-Specific Invariance

    DTIC Science & Technology

    1994-04-01

    underlie recognition of geon-like com- ponents (see Edelman, 1991 and Biederman , 1987 ). I(X -_ ta)II1y = (X - ta)TWTW(x -_ ta) (3) View-invariant features...Institute of Technology, 1993. neocortex. Biological Cybernetics, 1992. 14] I. Biederman . Recognition by components: a theory [20] B. Olshausen, C...Anderson, and D. Van Essen. A of human image understanding. Psychol. Review, neural model of visual attention and invariant pat- 94:115-147, 1987 . tern

  1. D Web Visualization of Environmental Information - Integration of Heterogeneous Data Sources when Providing Navigation and Interaction

    NASA Astrophysics Data System (ADS)

    Herman, L.; Řezník, T.

    2015-08-01

    3D information is essential for a number of applications used daily in various domains such as crisis management, energy management, urban planning, and cultural heritage, as well as pollution and noise mapping, etc. This paper is devoted to the issue of 3D modelling from the levels of buildings to cities. The theoretical sections comprise an analysis of cartographic principles for the 3D visualization of spatial data as well as a review of technologies and data formats used in the visualization of 3D models. Emphasis was placed on the verification of available web technologies; for example, X3DOM library was chosen for the implementation of a proof-of-concept web application. The created web application displays a 3D model of the city district of Nový Lískovec in Brno, the Czech Republic. The developed 3D visualization shows a terrain model, 3D buildings, noise pollution, and other related information. Attention was paid to the areas important for handling heterogeneous input data, the design of interactive functionality, and navigation assistants. The advantages, limitations, and future development of the proposed concept are discussed in the conclusions.

  2. Verbal Dominant Memory Impairment and Low Risk for Post-operative Memory Worsening in Both Left and Right Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis.

    PubMed

    Khalil, Amr Farid; Iwasaki, Masaki; Nishio, Yoshiyuki; Jin, Kazutaka; Nakasato, Nobukazu; Tominaga, Teiji

    2016-11-15

    Post-operative memory changes after temporal lobe surgery have been established mainly by group analysis of cognitive outcome. This study investigated individual patient-based memory outcome in surgically-treated patients with mesial temporal lobe epilepsy (TLE). This study included 84 consecutive patients with intractable TLE caused by unilateral hippocampal sclerosis (HS) who underwent epilepsy surgery (47 females, 41 left [Lt] TLE). Memory functions were evaluated with the Wechsler Memory Scale-Revised before and at 1 year after surgery. Pre-operative memory function was classified into three patterns: verbal dominant memory impairment (Verb-D), visual dominant impairment (Vis-D), and no material-specific impairment. Post-operative changes in verbal and visual memory indices were classified into meaningful improvement, worsening, or no significant changes. Pre-operative patterns and post-operative changes in verbal and visual memory function were compared between the Lt and right (Rt) TLE groups. Pre-operatively, Verb-D was the most common type of impairment in both the Lt and Rt TLE groups (65.9 and 48.8%), and verbal memory indices were lower than visual memory indices, especially in the Lt compared with Rt TLE group. Vis-D was observed only in 11.6% of Rt and 7.3% of Lt TLE patients. Post-operatively, meaningful improvement of memory indices was observed in 23.3-36.6% of the patients, and the memory improvement was equivalent between Lt and Rt TLE groups and between verbal and visual materials. In conclusion, Verb-D is most commonly observed in patients with both the Lt and Rt TLE associated with HS. Hippocampectomy can improve memory indices in such patients regardless of the side of surgery and the function impaired.

  3. 360-degree 3D transvaginal ultrasound system for high-dose-rate interstitial gynaecological brachytherapy needle guidance

    NASA Astrophysics Data System (ADS)

    Rodgers, Jessica R.; Surry, Kathleen; D'Souza, David; Leung, Eric; Fenster, Aaron

    2017-03-01

    Treatment for gynaecological cancers often includes brachytherapy; in particular, in high-dose-rate (HDR) interstitial brachytherapy, hollow needles are inserted into the tumour and surrounding area through a template in order to deliver the radiation dose. Currently, there is no standard modality for visualizing needles intra-operatively, despite the need for precise needle placement in order to deliver the optimal dose and avoid nearby organs, including the bladder and rectum. While three-dimensional (3D) transrectal ultrasound (TRUS) imaging has been proposed for 3D intra-operative needle guidance, anterior needles tend to be obscured by shadowing created by the template's vaginal cylinder. We have developed a 360-degree 3D transvaginal ultrasound (TVUS) system that uses a conventional two-dimensional side-fire TRUS probe rotated inside a hollow vaginal cylinder made from a sonolucent plastic (TPX). The system was validated using grid and sphere phantoms in order to test the geometric accuracy of the distance and volumetric measurements in the reconstructed image. To test the potential for visualizing needles, an agar phantom mimicking the geometry of the female pelvis was used. Needles were inserted into the phantom and then imaged using the 3D TVUS system. The needle trajectories and tip positions in the 3D TVUS scan were compared to their expected values and the needle tracks visualized in magnetic resonance images. Based on this initial study, 360-degree 3D TVUS imaging through a sonolucent vaginal cylinder is a feasible technique for intra-operatively visualizing needles during HDR interstitial gynaecological brachytherapy.

  4. Twin robotic x-ray system for 2D radiographic and 3D cone-beam CT imaging

    NASA Astrophysics Data System (ADS)

    Fieselmann, Andreas; Steinbrener, Jan; Jerebko, Anna K.; Voigt, Johannes M.; Scholz, Rosemarie; Ritschl, Ludwig; Mertelmeier, Thomas

    2016-03-01

    In this work, we provide an initial characterization of a novel twin robotic X-ray system. This system is equipped with two motor-driven telescopic arms carrying X-ray tube and flat-panel detector, respectively. 2D radiographs and fluoroscopic image sequences can be obtained from different viewing angles. Projection data for 3D cone-beam CT reconstruction can be acquired during simultaneous movement of the arms along dedicated scanning trajectories. We provide an initial evaluation of the 3D image quality based on phantom scans and clinical images. Furthermore, initial evaluation of patient dose is conducted. The results show that the system delivers high image quality for a range of medical applications. In particular, high spatial resolution enables adequate visualization of bone structures. This system allows 3D X-ray scanning of patients in standing and weight-bearing position. It could enable new 2D/3D imaging workflows in musculoskeletal imaging and improve diagnosis of musculoskeletal disorders.

  5. 3D gaze tracking system for NVidia 3D Vision®.

    PubMed

    Wibirama, Sunu; Hamamoto, Kazuhiko

    2013-01-01

    Inappropriate parallax setting in stereoscopic content generally causes visual fatigue and visual discomfort. To optimize three dimensional (3D) effects in stereoscopic content by taking into account health issue, understanding how user gazes at 3D direction in virtual space is currently an important research topic. In this paper, we report the study of developing a novel 3D gaze tracking system for Nvidia 3D Vision(®) to be used in desktop stereoscopic display. We suggest an optimized geometric method to accurately measure the position of virtual 3D object. Our experimental result shows that the proposed system achieved better accuracy compared to conventional geometric method by average errors 0.83 cm, 0.87 cm, and 1.06 cm in X, Y, and Z dimensions, respectively.

  6. Virtual taphonomy using synchrotron tomographic microscopy reveals cryptic features and internal structure of modern and fossil plants

    PubMed Central

    Smith, Selena Y.; Collinson, Margaret E.; Rudall, Paula J.; Simpson, David A.; Marone, Federica; Stampanoni, Marco

    2009-01-01

    While more commonly applied in zoology, synchrotron radiation X-ray tomographic microscopy (SRXTM) is well-suited to nondestructive study of the morphology and anatomy of both fossil and modern plants. SRXTM uses hard X-rays and a monochromatic light source to provide high-resolution data with little beam-hardening, resulting in slice data with clear boundaries between materials. Anatomy is readily visualized, including various planes of section from a single specimen, as clear as in traditional histological sectioning at low magnifications. Thus, digital sectioning of rare or difficult material is possible. Differential X-ray attenuation allows visualization of different layers or chemistries to enable virtual 3-dimensional (3D) dissections of material. Virtual potential fossils can be visualized and digital tissue removal reveals cryptic underlying morphology. This is essential for fossil identification and for comparisons between assemblages where fossils are preserved by different means. SRXTM is a powerful approach for botanical studies using morphology and anatomy. The ability to gain search images in both 2D and 3D for potential fossils gives paleobotanists a tool—virtual taphonomy—to improve our understanding of plant evolution and paleobiogeography. PMID:19574457

  7. Java 3D Interactive Visualization for Astrophysics

    NASA Astrophysics Data System (ADS)

    Chae, K.; Edirisinghe, D.; Lingerfelt, E. J.; Guidry, M. W.

    2003-05-01

    We are developing a series of interactive 3D visualization tools that employ the Java 3D API. We have applied this approach initially to a simple 3-dimensional galaxy collision model (restricted 3-body approximation), with quite satisfactory results. Running either as an applet under Web browser control, or as a Java standalone application, this program permits real-time zooming, panning, and 3-dimensional rotation of the galaxy collision simulation under user mouse and keyboard control. We shall also discuss applications of this technology to 3-dimensional visualization for other problems of astrophysical interest such as neutron star mergers and the time evolution of element/energy production networks in X-ray bursts. *Managed by UT-Battelle, LLC, for the U.S. Department of Energy under contract DE-AC05-00OR22725.

  8. Microtomographic images of rat's lumbar vertebra microstructure using 30 keV synchrotron X-rays: an analysis in terms of 3D visualization

    NASA Astrophysics Data System (ADS)

    Rao, D. V.; Takeda, T.; Kawakami, T.; Uesugi, K.; Tsuchiya, Y.; Wu, J.; Lwin, T. T.; Itai, Y.; Zeniya, T.; Yuasa, T.; Akatsuka, T.

    2004-05-01

    Microtomographic images of rat's lumbar vertebra of different age groups varying from 8, 56 and 78 weeks were obtained at 30 keV using synchrotron X-rays with a spatial resolution of 12 μm. The images are analyzed in terms of 3D visualization and micro-architecture. Density histogram of rat's lumbar vertebra is compared with test phantoms. Rat's lumbar volume and phantom volume are studied at different concentrations of hydroxyapatite with slice number. With the use of 2D slices, 3D images are reconstructed, in order to know the evolution and a state of decline of bone microstructure with aging. Cross-sectional μ-CT images shows that the bone of young rat has a fine trabecular microstructure while that of the old rat has large meshed structure.

  9. Non Destructive 3D X-Ray Imaging of Nano Structures & Composites at Sub-30 NM Resolution, With a Novel Lab Based X-Ray Microscope

    DTIC Science & Technology

    2006-11-01

    NON DESTRUCTIVE 3D X-RAY IMAGING OF NANO STRUCTURES & COMPOSITES AT SUB-30 NM RESOLUTION, WITH A NOVEL LAB BASED X- RAY MICROSCOPE S H Lau...article we describe a 3D x-ray microscope based on a laboratory x-ray source operating at 2.7, 5.4 or 8.0 keV hard x-ray energies. X-ray computed...tomography (XCT) is used to obtain detailed 3D structural information inside optically opaque materials with sub-30 nm resolution. Applications include

  10. High End Visualization of Geophysical Datasets Using Immersive Technology: The SIO Visualization Center.

    NASA Astrophysics Data System (ADS)

    Newman, R. L.

    2002-12-01

    How many images can you display at one time with Power Point without getting "postage stamps"? Do you have fantastic datasets that you cannot view because your computer is too slow/small? Do you assume a few 2-D images of a 3-D picture are sufficient? High-end visualization centers can minimize and often eliminate these problems. The new visualization center [http://siovizcenter.ucsd.edu] at Scripps Institution of Oceanography [SIO] immerses users into a virtual world by projecting 3-D images onto a Panoram GVR-120E wall-sized floor-to-ceiling curved screen [7' x 23'] that has 3.2 mega-pixels of resolution. The Infinite Reality graphics subsystem is driven by a single-pipe SGI Onyx 3400 with a system bandwidth of 44 Gbps. The Onyx is powered by 16 MIPS R12K processors and 16 GB of addressable memory. The system is also equipped with transmitters and LCD shutter glasses which permit stereographic 3-D viewing of high-resolution images. This center is ideal for groups of up to 60 people who can simultaneously view these large-format images. A wide range of hardware and software is available, giving the users a totally immersive working environment in which to display, analyze, and discuss large datasets. The system enables simultaneous display of video and audio streams from sources such as SGI megadesktop and stereo megadesktop, S-VHS video, DVD video, and video from a Macintosh or PC. For instance, one-third of the screen might be displaying S-VHS video from a remotely-operated-vehicle [ROV], while the remaining portion of the screen might be used for an interactive 3-D flight over the same parcel of seafloor. The video and audio combinations using this system are numerous, allowing users to combine and explore data and images in innovative ways, greatly enhancing scientists' ability to visualize, understand and collaborate on complex datasets. In the not-distant future, with the rapid growth in networking speeds in the US, it will be possible for Earth Sciences Departments to collaborate effectively while limiting the amount of physical travel required. This includes porting visualization content to the popular, low-cost Geowall visualization systems, and providing web-based access to databanks filled with stock geoscience visualizations.

  11. Evaluation of low-dose limits in 3D-2D rigid registration for surgical guidance

    NASA Astrophysics Data System (ADS)

    Uneri, A.; Wang, A. S.; Otake, Y.; Kleinszig, G.; Vogt, S.; Khanna, A. J.; Gallia, G. L.; Gokaslan, Z. L.; Siewerdsen, J. H.

    2014-09-01

    An algorithm for intensity-based 3D-2D registration of CT and C-arm fluoroscopy is evaluated for use in surgical guidance, specifically considering the low-dose limits of the fluoroscopic x-ray projections. The registration method is based on a framework using the covariance matrix adaptation evolution strategy (CMA-ES) to identify the 3D patient pose that maximizes the gradient information similarity metric. Registration performance was evaluated in an anthropomorphic head phantom emulating intracranial neurosurgery, using target registration error (TRE) to characterize accuracy and robustness in terms of 95% confidence upper bound in comparison to that of an infrared surgical tracking system. Three clinical scenarios were considered: (1) single-view image + guidance, wherein a single x-ray projection is used for visualization and 3D-2D guidance; (2) dual-view image + guidance, wherein one projection is acquired for visualization, combined with a second (lower-dose) projection acquired at a different C-arm angle for 3D-2D guidance; and (3) dual-view guidance, wherein both projections are acquired at low dose for the purpose of 3D-2D guidance alone (not visualization). In each case, registration accuracy was evaluated as a function of the entrance surface dose associated with the projection view(s). Results indicate that images acquired at a dose as low as 4 μGy (approximately one-tenth the dose of a typical fluoroscopic frame) were sufficient to provide TRE comparable or superior to that of conventional surgical tracking, allowing 3D-2D guidance at a level of dose that is at most 10% greater than conventional fluoroscopy (scenario #2) and potentially reducing the dose to approximately 20% of the level in a conventional fluoroscopically guided procedure (scenario #3).

  12. Dual-mode intracranial catheter integrating 3D ultrasound imaging and hyperthermia for neuro-oncology: feasibility study.

    PubMed

    Herickhoff, Carl D; Light, Edward D; Bing, Kristin F; Mukundan, Srinivasan; Grant, Gerald A; Wolf, Patrick D; Smith, Stephen W

    2009-04-01

    In this study, we investigated the feasibility of an intracranial catheter transducer with dual-mode capability of real-time 3D (RT3D) imaging and ultrasound hyperthermia, for application in the visualization and treatment of tumors in the brain. Feasibility is demonstrated in two ways: first by using a 50-element linear array transducer (17 mm x 3.1 mm aperture) operating at 4.4 MHz with our Volumetrics diagnostic scanner and custom, electrical impedance-matching circuits to achieve a temperature rise over 4 degrees C in excised pork muscle, and second, by designing and constructing a 12 Fr, integrated matrix and linear-array catheter transducer prototype for combined RT3D imaging and heating capability. This dual-mode catheter incorporated 153 matrix array elements and 11 linear array elements diced on a 0.2 mm pitch, with a total aperture size of 8.4 mm x 2.3 mm. This 3.64 MHz array achieved a 3.5 degrees C in vitro temperature rise at a 2 cm focal distance in tissue-mimicking material. The dual-mode catheter prototype was compared with a Siemens 10 Fr AcuNav catheter as a gold standard in experiments assessing image quality and therapeutic potential and both probes were used in an in vivo canine brain model to image anatomical structures and color Doppler blood flow and to attempt in vivo heating.

  13. Interrogation of patient data delivered to the operating theatre during hepato-pancreatic surgery using high-performance computing.

    PubMed

    John, Nigel W; McCloy, Rory F; Herrman, Simone

    2004-01-01

    The Op3D visualization system allows, for the first time, a surgeon in the operating theatre to interrogate patient-specific medical data sets rendered in three dimensions using high-performance computing. The hypothesis of this research is that the success rate of hepato-pancreatic surgical resections can be improved by replacing the light box with an interactive 3D representation of the medical data in the operating theatre. A laptop serves as the client computer and an easy-to-use interface has been developed for the surgeon to interact with and interrogate the patient data. To date, 16 patients have had 3D reconstructions of their DICOM data sets, including preoperative interrogation and planning of surgery. Interrogation of the 3D images live in theatre and comparison with the surgeons' operative findings (including intraoperative ultrasound) led to the operation being abandoned in 25% of cases, adoption of an alternative surgical approach in 25% of cases, and helpful image guidance for successful resection in 50% of cases. The clinical value of the latest generation of scanners and digital imaging techniques cannot be realized unless appropriate dissemination of the images takes place. This project has succeeded in translating the image technology into a user-friendly form and delivers 3D reconstructions of patient-specific data to the "sharp end"-the surgeon undertaking the tumor resection in theatre, in a manner that allows interaction and interpretation. More time interrogating the 3D data sets preoperatively would help reduce the incidence of abandoned operations-this is part of the surgeons' learning curve. We have developed one of the first practical applications to benefit from remote visualization, and certainly the first medical visualization application of this kind.

  14. D Modelling and Visualization Based on the Unity Game Engine - Advantages and Challenges

    NASA Astrophysics Data System (ADS)

    Buyuksalih, I.; Bayburt, S.; Buyuksalih, G.; Baskaraca, A. P.; Karim, H.; Rahman, A. A.

    2017-11-01

    3D City modelling is increasingly popular and becoming valuable tools in managing big cities. Urban and energy planning, landscape, noise-sewage modelling, underground mapping and navigation are among the applications/fields which really depend on 3D modelling for their effectiveness operations. Several research areas and implementation projects had been carried out to provide the most reliable 3D data format for sharing and functionalities as well as visualization platform and analysis. For instance, BIMTAS company has recently completed a project to estimate potential solar energy on 3D buildings for the whole Istanbul and now focussing on 3D utility underground mapping for a pilot case study. The research and implementation standard on 3D City Model domain (3D data sharing and visualization schema) is based on CityGML schema version 2.0. However, there are some limitations and issues in implementation phase for large dataset. Most of the limitations were due to the visualization, database integration and analysis platform (Unity3D game engine) as highlighted in this paper.

  15. Automated UAV-based video exploitation using service oriented architecture framework

    NASA Astrophysics Data System (ADS)

    Se, Stephen; Nadeau, Christian; Wood, Scott

    2011-05-01

    Airborne surveillance and reconnaissance are essential for successful military missions. Such capabilities are critical for troop protection, situational awareness, mission planning, damage assessment, and others. Unmanned Aerial Vehicles (UAVs) gather huge amounts of video data but it is extremely labour-intensive for operators to analyze hours and hours of received data. At MDA, we have developed a suite of tools that can process the UAV video data automatically, including mosaicking, change detection and 3D reconstruction, which have been integrated within a standard GIS framework. In addition, the mosaicking and 3D reconstruction tools have also been integrated in a Service Oriented Architecture (SOA) framework. The Visualization and Exploitation Workstation (VIEW) integrates 2D and 3D visualization, processing, and analysis capabilities developed for UAV video exploitation. Visualization capabilities are supported through a thick-client Graphical User Interface (GUI), which allows visualization of 2D imagery, video, and 3D models. The GUI interacts with the VIEW server, which provides video mosaicking and 3D reconstruction exploitation services through the SOA framework. The SOA framework allows multiple users to perform video exploitation by running a GUI client on the operator's computer and invoking the video exploitation functionalities residing on the server. This allows the exploitation services to be upgraded easily and allows the intensive video processing to run on powerful workstations. MDA provides UAV services to the Canadian and Australian forces in Afghanistan with the Heron, a Medium Altitude Long Endurance (MALE) UAV system. On-going flight operations service provides important intelligence, surveillance, and reconnaissance information to commanders and front-line soldiers.

  16. Spatial 3D infrastructure: display-independent software framework, high-speed rendering electronics, and several new displays

    NASA Astrophysics Data System (ADS)

    Chun, Won-Suk; Napoli, Joshua; Cossairt, Oliver S.; Dorval, Rick K.; Hall, Deirdre M.; Purtell, Thomas J., II; Schooler, James F.; Banker, Yigal; Favalora, Gregg E.

    2005-03-01

    We present a software and hardware foundation to enable the rapid adoption of 3-D displays. Different 3-D displays - such as multiplanar, multiview, and electroholographic displays - naturally require different rendering methods. The adoption of these displays in the marketplace will be accelerated by a common software framework. The authors designed the SpatialGL API, a new rendering framework that unifies these display methods under one interface. SpatialGL enables complementary visualization assets to coexist through a uniform infrastructure. Also, SpatialGL supports legacy interfaces such as the OpenGL API. The authors" first implementation of SpatialGL uses multiview and multislice rendering algorithms to exploit the performance of modern graphics processing units (GPUs) to enable real-time visualization of 3-D graphics from medical imaging, oil & gas exploration, and homeland security. At the time of writing, SpatialGL runs on COTS workstations (both Windows and Linux) and on Actuality"s high-performance embedded computational engine that couples an NVIDIA GeForce 6800 Ultra GPU, an AMD Athlon 64 processor, and a proprietary, high-speed, programmable volumetric frame buffer that interfaces to a 1024 x 768 x 3 digital projector. Progress is illustrated using an off-the-shelf multiview display, Actuality"s multiplanar Perspecta Spatial 3D System, and an experimental multiview display. The experimental display is a quasi-holographic view-sequential system that generates aerial imagery measuring 30 mm x 25 mm x 25 mm, providing 198 horizontal views.

  17. Three-dimensional reconstruction of the topographical cerebral surface anatomy for presurgical planning with free OsiriX Software.

    PubMed

    Harput, Mehmet V; Gonzalez-Lopez, Pablo; Türe, Uğur

    2014-09-01

    During surgery for intrinsic brain lesions, it is important to distinguish the pathological gyrus from the surrounding normal sulci and gyri. This task is usually tedious because of the pia-arachnoid membranes with their arterial and venous complexes that obscure the underlying anatomy. Moreover, most tumors grow in the white matter without initially distorting the cortical anatomy, making their direct visualization more difficult. To create and evaluate a simple and free surgical planning tool to simulate the anatomy of the surgical field with and without vessels. We used free computer software (OsiriX Medical Imaging Software) that allowed us to create 3-dimensional reconstructions of the cerebral surface with and without cortical vessels. These reconstructions made use of magnetic resonance images from 51 patients with neocortical supratentorial lesions operated on over a period of 21 months (June 2011 to February 2013). The 3-dimensional (3-D) anatomic images were compared with the true surgical view to evaluate their accuracy. In all patients, the landmarks determined by 3-D reconstruction were cross-checked during surgery with high-resolution ultrasonography; in select cases, they were also checked with indocyanine green videoangiography. The reconstructed neurovascular structures were confirmed intraoperatively in all patients. We found this technique to be extremely useful in achieving pure lesionectomy, as it defines tumor's borders precisely. A 3-D reconstruction of the cortical surface can be easily created with free OsiriX software. This technique helps the surgeon perfect the mentally created 3-D picture of the tumor location to carry out cleaner, safer surgeries.

  18. [An alternative to the usual operating microscope and loupe magnification for free microvascular tissue transfer. Varioscope AF3-A].

    PubMed

    Chiummariello, S; Alfano, C; Fioramonti, P; Scuderi, N

    2005-12-01

    Free microvascular tissue transfers have become today a key instrument for the surgical treatment of wide loss of tissue, but their employment implies mandatory use of the right visual magnification means. Until now these instruments were mainly loupes and operating microscopes. Our study is focusing on the use of a new visual system--Varioscope AF3-A--in the reconstructive microsurgery field. Varioscope AF3-A (Life Optics, Vienna, Austria) has been employed in our Institute in 10 microvascular reconstructions, where different free flaps were used in head and neck reconstruction. All the flaps took and only one developed a partial necrosis. We have also noticed, by using this new instrument, a learning curve with a progressive contraction of the operating time. In all cases we have operated on 2 mm caliber vessels or more and on tissues that didn't previously undergo radiation therapy. The employment of a visual magnification mean, as Varioscope AF3-A, allows autofocus (from 3.6X to 7.2X) and a wide vision. It can be easily used with substantial advantages for the surgeon in performing microvascular anastomosis. Partial drawbacks are the equipment high cost and weight, compared to the loupes and a stronger ocular stress due to the continuous autofocus compared to the static operating microscopes.

  19. High Resolution Visualization Applied to Future Heavy Airlift Concept Development and Evaluation

    NASA Technical Reports Server (NTRS)

    FordCook, A. B.; King, T.

    2012-01-01

    This paper explores the use of high resolution 3D visualization tools for exploring the feasibility and advantages of future military cargo airlift concepts and evaluating compatibility with existing and future payload requirements. Realistic 3D graphic representations of future airlifters are immersed in rich, supporting environments to demonstrate concepts of operations to key personnel for evaluation, feedback, and development of critical joint support. Accurate concept visualizations are reviewed by commanders, platform developers, loadmasters, soldiers, scientists, engineers, and key principal decision makers at various stages of development. The insight gained through the review of these physically and operationally realistic visualizations is essential to refining design concepts to meet competing requirements in a fiscally conservative defense finance environment. In addition, highly accurate 3D geometric models of existing and evolving large military vehicles are loaded into existing and proposed aircraft cargo bays. In this virtual aircraft test-loading environment, materiel developers, engineers, managers, and soldiers can realistically evaluate the compatibility of current and next-generation airlifters with proposed cargo.

  20. Virtual Reality in Neurointervention.

    PubMed

    Ong, Chin Siang; Deib, Gerard; Yesantharao, Pooja; Qiao, Ye; Pakpoor, Jina; Hibino, Narutoshi; Hui, Ferdinand; Garcia, Juan R

    2018-06-01

    Virtual reality (VR) allows users to experience realistic, immersive 3D virtual environments with the depth perception and binocular field of view of real 3D settings. Newer VR technology has now allowed for interaction with 3D objects within these virtual environments through the use of VR controllers. This technical note describes our preliminary experience with VR as an adjunct tool to traditional angiographic imaging in the preprocedural workup of a patient with a complex pseudoaneurysm. Angiographic MRI data was imported and segmented to create 3D meshes of bilateral carotid vasculature. The 3D meshes were then projected into VR space, allowing the operator to inspect the carotid vasculature using a 3D VR headset as well as interact with the pseudoaneurysm (handling, rotation, magnification, and sectioning) using two VR controllers. 3D segmentation of a complex pseudoaneurysm in the distal cervical segment of the right internal carotid artery was successfully performed and projected into VR. Conventional and VR visualization modes were equally effective in identifying and classifying the pathology. VR visualization allowed the operators to manipulate the dataset to achieve a greater understanding of the anatomy of the parent vessel, the angioarchitecture of the pseudoaneurysm, and the surface contours of all visualized structures. This preliminary study demonstrates the feasibility of utilizing VR for preprocedural evaluation in patients with anatomically complex neurovascular disorders. This novel visualization approach may serve as a valuable adjunct tool in deciding patient-specific treatment plans and selection of devices prior to intervention.

  1. Movement-based estimation and visualization of space use in 3D for wildlife ecology and conservation

    USGS Publications Warehouse

    Tracey, Jeff A.; Sheppard, James; Zhu, Jun; Wei, Fu-Wen; Swaisgood, Ronald R.; Fisher, Robert N.

    2014-01-01

    Advances in digital biotelemetry technologies are enabling the collection of bigger and more accurate data on the movements of free-ranging wildlife in space and time. Although many biotelemetry devices record 3D location data with x, y, and z coordinates from tracked animals, the third z coordinate is typically not integrated into studies of animal spatial use. Disregarding the vertical component may seriously limit understanding of animal habitat use and niche separation. We present novel movement-based kernel density estimators and computer visualization tools for generating and exploring 3D home ranges based on location data. We use case studies of three wildlife species – giant panda, dugong, and California condor – to demonstrate the ecological insights and conservation management benefits provided by 3D home range estimation and visualization for terrestrial, aquatic, and avian wildlife research.

  2. Movement-Based Estimation and Visualization of Space Use in 3D for Wildlife Ecology and Conservation

    PubMed Central

    Tracey, Jeff A.; Sheppard, James; Zhu, Jun; Wei, Fuwen; Swaisgood, Ronald R.; Fisher, Robert N.

    2014-01-01

    Advances in digital biotelemetry technologies are enabling the collection of bigger and more accurate data on the movements of free-ranging wildlife in space and time. Although many biotelemetry devices record 3D location data with x, y, and z coordinates from tracked animals, the third z coordinate is typically not integrated into studies of animal spatial use. Disregarding the vertical component may seriously limit understanding of animal habitat use and niche separation. We present novel movement-based kernel density estimators and computer visualization tools for generating and exploring 3D home ranges based on location data. We use case studies of three wildlife species – giant panda, dugong, and California condor – to demonstrate the ecological insights and conservation management benefits provided by 3D home range estimation and visualization for terrestrial, aquatic, and avian wildlife research. PMID:24988114

  3. PACS-based interface for 3D anatomical structure visualization and surgical planning

    NASA Astrophysics Data System (ADS)

    Koehl, Christophe; Soler, Luc; Marescaux, Jacques

    2002-05-01

    The interpretation of radiological image is routine but it remains a rather difficult task for physicians. It requires complex mental processes, that permit translation from 2D slices into 3D localization and volume determination of visible diseases. An easier and more extensive visualization and exploitation of medical images can be reached through the use of computer-based systems that provide real help from patient admission to post-operative followup. In this way, we have developed a 3D visualization interface linked to a PACS database that allows manipulation and interaction on virtual organs delineated from CT-scan or MRI. This software provides the 3D real-time surface rendering of anatomical structures, an accurate evaluation of volumes and distances and the improvement of radiological image analysis and exam annotation through a negatoscope tool. It also provides a tool for surgical planning allowing the positioning of an interactive laparoscopic instrument and the organ resection. The software system could revolutionize the field of computerized imaging technology. Indeed, it provides a handy and portable tool for pre-operative and intra-operative analysis of anatomy and pathology in various medical fields. This constitutes the first step of the future development of augmented reality and surgical simulation systems.

  4. Real-time 3D visualization of volumetric video motion sensor data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carlson, J.; Stansfield, S.; Shawver, D.

    1996-11-01

    This paper addresses the problem of improving detection, assessment, and response capabilities of security systems. Our approach combines two state-of-the-art technologies: volumetric video motion detection (VVMD) and virtual reality (VR). This work capitalizes on the ability of VVMD technology to provide three-dimensional (3D) information about the position, shape, and size of intruders within a protected volume. The 3D information is obtained by fusing motion detection data from multiple video sensors. The second component involves the application of VR technology to display information relating to the sensors and the sensor environment. VR technology enables an operator, or security guard, to bemore » immersed in a 3D graphical representation of the remote site. VVMD data is transmitted from the remote site via ordinary telephone lines. There are several benefits to displaying VVMD information in this way. Because the VVMD system provides 3D information and because the sensor environment is a physical 3D space, it seems natural to display this information in 3D. Also, the 3D graphical representation depicts essential details within and around the protected volume in a natural way for human perception. Sensor information can also be more easily interpreted when the operator can `move` through the virtual environment and explore the relationships between the sensor data, objects and other visual cues present in the virtual environment. By exploiting the powerful ability of humans to understand and interpret 3D information, we expect to improve the means for visualizing and interpreting sensor information, allow a human operator to assess a potential threat more quickly and accurately, and enable a more effective response. This paper will detail both the VVMD and VR technologies and will discuss a prototype system based upon their integration.« less

  5. Navigation-aided visualization of lumbosacral nerves for anterior sacroiliac plate fixation: a case report.

    PubMed

    Takao, Masaki; Nishii, Takashi; Sakai, Takashi; Sugano, Nobuhiko

    2014-06-01

    Anterior sacroiliac joint plate fixation for unstable pelvic ring fractures avoids soft tissue problems in the buttocks; however, the lumbosacral nerves lie in close proximity to the sacroiliac joint and may be injured during the procedure. A 49 year-old woman with a type C pelvic ring fracture was treated with an anterior sacroiliac plate using a computed tomography (CT)-three-dimensional (3D)-fluoroscopy matching navigation system, which visualized the lumbosacral nerves as well as the iliac and sacral bones. We used a flat panel detector 3D C-arm, which made it possible to superimpose our preoperative CT-based plan on the intra-operative 3D-fluoroscopic images. No postoperative complications were noted. Intra-operative lumbosacral nerve visualization using computer navigation was useful to recognize the 'at-risk' area for nerve injury during anterior sacroiliac plate fixation. Copyright © 2013 John Wiley & Sons, Ltd.

  6. Respiratory motion estimation in x-ray angiography for improved guidance during coronary interventions

    NASA Astrophysics Data System (ADS)

    Baka, N.; Lelieveldt, B. P. F.; Schultz, C.; Niessen, W.; van Walsum, T.

    2015-05-01

    During percutaneous coronary interventions (PCI) catheters and arteries are visualized by x-ray angiography (XA) sequences, using brief contrast injections to show the coronary arteries. If we could continue visualizing the coronary arteries after the contrast agent passed (thus in non-contrast XA frames), we could potentially lower contrast use, which is advantageous due to the toxicity of the contrast agent. This paper explores the possibility of such visualization in mono-plane XA acquisitions with a special focus on respiratory based coronary artery motion estimation. We use the patient specific coronary artery centerlines from pre-interventional 3D CTA images to project on the XA sequence for artery visualization. To achieve this, a framework for registering the 3D centerlines with the mono-plane 2D + time XA sequences is presented. During the registration the patient specific cardiac and respiratory motion is learned. We investigate several respiratory motion estimation strategies with respect to accuracy, plausibility and ease of use for motion prediction in XA frames with and without contrast. The investigated strategies include diaphragm motion based prediction, and respiratory motion extraction from the guiding catheter tip motion. We furthermore compare translational and rigid respiratory based heart motion. We validated the accuracy of the 2D/3D registration and the respiratory and cardiac motion estimations on XA sequences of 12 interventions. The diaphragm based motion model and the catheter tip derived motion achieved 1.58 mm and 1.83 mm median 2D accuracy, respectively. On a subset of four interventions we evaluated the artery visualization accuracy for non-contrast cases. Both diaphragm, and catheter tip based prediction performed similarly, with about half of the cases providing satisfactory accuracy (median error < 2 mm).

  7. Hard X-ray submicrometer tomography of human brain tissue at Diamond Light Source

    NASA Astrophysics Data System (ADS)

    Khimchenko, A.; Bikis, C.; Schulz, G.; Zdora, M.-C.; Zanette, I.; Vila-Comamala, J.; Schweighauser, G.; Hench, J.; Hieber, S. E.; Deyhle, H.; Thalmann, P.; Müller, B.

    2017-06-01

    There is a lack of the necessary methodology for three-dimensional (3D) investigation of soft tissues with cellular resolution without staining or tissue transformation. Synchrotron radiation based hard X-ray in-line phase contrast tomography using single-distance phase reconstruction (SDPR) provides high spatial resolution and density contrast for the visualization of individual cells using a standard specimen preparation and data reconstruction. In this study, we demonstrate the 3D characterization of a formalin-fixed paraffin-embedded (FFPE) human cerebellum specimen by SDPR at the Diamond-Manchester Imaging Branchline I13-2 (Diamond Light Source, UK) at pixel sizes down to 0.45 μm. The approach enables visualization of cerebellar layers (Stratum moleculare and Stratum granulosum), the 3D characterization of individual cells (Purkinje, stellate and granule cells) and can even resolve some subcellular structures (nucleus and nucleolus of Purkinje cells). The tomographic results are qualitatively compared to hematoxylin and eosin (H&E) stained histological sections. We demonstrate the potential benefits of hard X-ray microtomography for the investigations of biological tissues in comparison to conventional histology.

  8. A 3D contact analysis approach for the visualization of the electrical contact asperities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roussos, Constantinos C.; Swingler, Jonathan

    The electrical contact is an important phenomenon that should be given into consideration to achieve better performance and long term reliability for the design of devices. Based upon this importance, the electrical contact interface has been visualized as a “3D Contact Map” and used in order to investigate the contact asperities. The contact asperities describe the structures above and below the contact spots (the contact spots define the 3D contact map) to the two conductors which make the contact system. The contact asperities require the discretization of the 3D microstructures of the contact system into voxels. A contact analysis approachmore » has been developed and introduced in this paper which shows the way to the 3D visualization of the contact asperities of a given contact system. For the discretization of 3D microstructure of contact system into voxels, X-ray Computed Tomography (CT) method is used in order to collect the data of a 250 V, 16 A rated AC single pole rocker switch which is used as a contact system for investigation.« less

  9. A 3D contact analysis approach for the visualization of the electrical contact asperities

    PubMed Central

    Swingler, Jonathan

    2017-01-01

    The electrical contact is an important phenomenon that should be given into consideration to achieve better performance and long term reliability for the design of devices. Based upon this importance, the electrical contact interface has been visualized as a ‘‘3D Contact Map’’ and used in order to investigate the contact asperities. The contact asperities describe the structures above and below the contact spots (the contact spots define the 3D contact map) to the two conductors which make the contact system. The contact asperities require the discretization of the 3D microstructures of the contact system into voxels. A contact analysis approach has been developed and introduced in this paper which shows the way to the 3D visualization of the contact asperities of a given contact system. For the discretization of 3D microstructure of contact system into voxels, X-ray Computed Tomography (CT) method is used in order to collect the data of a 250 V, 16 A rated AC single pole rocker switch which is used as a contact system for investigation. PMID:28105383

  10. A 3D contact analysis approach for the visualization of the electrical contact asperities

    DOE PAGES

    Roussos, Constantinos C.; Swingler, Jonathan

    2017-01-11

    The electrical contact is an important phenomenon that should be given into consideration to achieve better performance and long term reliability for the design of devices. Based upon this importance, the electrical contact interface has been visualized as a “3D Contact Map” and used in order to investigate the contact asperities. The contact asperities describe the structures above and below the contact spots (the contact spots define the 3D contact map) to the two conductors which make the contact system. The contact asperities require the discretization of the 3D microstructures of the contact system into voxels. A contact analysis approachmore » has been developed and introduced in this paper which shows the way to the 3D visualization of the contact asperities of a given contact system. For the discretization of 3D microstructure of contact system into voxels, X-ray Computed Tomography (CT) method is used in order to collect the data of a 250 V, 16 A rated AC single pole rocker switch which is used as a contact system for investigation.« less

  11. High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s.

    PubMed

    Wieser, Wolfgang; Draxinger, Wolfgang; Klein, Thomas; Karpf, Sebastian; Pfeiffer, Tom; Huber, Robert

    2014-09-01

    We present a 1300 nm OCT system for volumetric real-time live OCT acquisition and visualization at 1 billion volume elements per second. All technological challenges and problems associated with such high scanning speed are discussed in detail as well as the solutions. In one configuration, the system acquires, processes and visualizes 26 volumes per second where each volume consists of 320 x 320 depth scans and each depth scan has 400 usable pixels. This is the fastest real-time OCT to date in terms of voxel rate. A 51 Hz volume rate is realized with half the frame number. In both configurations the speed can be sustained indefinitely. The OCT system uses a 1310 nm Fourier domain mode locked (FDML) laser operated at 3.2 MHz sweep rate. Data acquisition is performed with two dedicated digitizer cards, each running at 2.5 GS/s, hosted in a single desktop computer. Live real-time data processing and visualization are realized with custom developed software on an NVidia GTX 690 dual graphics processing unit (GPU) card. To evaluate potential future applications of such a system, we present volumetric videos captured at 26 and 51 Hz of planktonic crustaceans and skin.

  12. High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

    PubMed Central

    Wieser, Wolfgang; Draxinger, Wolfgang; Klein, Thomas; Karpf, Sebastian; Pfeiffer, Tom; Huber, Robert

    2014-01-01

    We present a 1300 nm OCT system for volumetric real-time live OCT acquisition and visualization at 1 billion volume elements per second. All technological challenges and problems associated with such high scanning speed are discussed in detail as well as the solutions. In one configuration, the system acquires, processes and visualizes 26 volumes per second where each volume consists of 320 x 320 depth scans and each depth scan has 400 usable pixels. This is the fastest real-time OCT to date in terms of voxel rate. A 51 Hz volume rate is realized with half the frame number. In both configurations the speed can be sustained indefinitely. The OCT system uses a 1310 nm Fourier domain mode locked (FDML) laser operated at 3.2 MHz sweep rate. Data acquisition is performed with two dedicated digitizer cards, each running at 2.5 GS/s, hosted in a single desktop computer. Live real-time data processing and visualization are realized with custom developed software on an NVidia GTX 690 dual graphics processing unit (GPU) card. To evaluate potential future applications of such a system, we present volumetric videos captured at 26 and 51 Hz of planktonic crustaceans and skin. PMID:25401010

  13. Mobile C-arm cone-beam CT for guidance of spine surgery: Image quality, radiation dose, and integration with interventional guidance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schafer, S.; Nithiananthan, S.; Mirota, D. J.

    Purpose: A flat-panel detector based mobile isocentric C-arm for cone-beam CT (CBCT) has been developed to allow intraoperative 3D imaging with sub-millimeter spatial resolution and soft-tissue visibility. Image quality and radiation dose were evaluated in spinal surgery, commonly relying on lower-performance image intensifier based mobile C-arms. Scan protocols were developed for task-specific imaging at minimum dose, in-room exposure was evaluated, and integration of the imaging system with a surgical guidance system was demonstrated in preclinical studies of minimally invasive spine surgery. Methods: Radiation dose was assessed as a function of kilovolt (peak) (80-120 kVp) and milliampere second using thoracic andmore » lumbar spine dosimetry phantoms. In-room radiation exposure was measured throughout the operating room for various CBCT scan protocols. Image quality was assessed using tissue-equivalent inserts in chest and abdomen phantoms to evaluate bone and soft-tissue contrast-to-noise ratio as a function of dose, and task-specific protocols (i.e., visualization of bone or soft-tissues) were defined. Results were applied in preclinical studies using a cadaveric torso simulating minimally invasive, transpedicular surgery. Results: Task-specific CBCT protocols identified include: thoracic bone visualization (100 kVp; 60 mAs; 1.8 mGy); lumbar bone visualization (100 kVp; 130 mAs; 3.2 mGy); thoracic soft-tissue visualization (100 kVp; 230 mAs; 4.3 mGy); and lumbar soft-tissue visualization (120 kVp; 460 mAs; 10.6 mGy) - each at (0.3 x 0.3 x 0.9 mm{sup 3}) voxel size. Alternative lower-dose, lower-resolution soft-tissue visualization protocols were identified (100 kVp; 230 mAs; 5.1 mGy) for the lumbar region at (0.3 x 0.3 x 1.5 mm{sup 3}) voxel size. Half-scan orbit of the C-arm (x-ray tube traversing under the table) was dosimetrically advantageous (prepatient attenuation) with a nonuniform dose distribution ({approx}2 x higher at the entrance side than at isocenter, and {approx}3-4 lower at the exit side). The in-room dose (microsievert) per unit scan dose (milligray) ranged from {approx}21 {mu}Sv/mGy on average at tableside to {approx}0.1 {mu}Sv/mGy at 2.0 m distance to isocenter. All protocols involve surgical staff stepping behind a shield wall for each CBCT scan, therefore imparting {approx}zero dose to staff. Protocol implementation in preclinical cadaveric studies demonstrate integration of the C-arm with a navigation system for spine surgery guidance-specifically, minimally invasive vertebroplasty in which the system provided accurate guidance and visualization of needle placement and bone cement distribution. Cumulative dose including multiple intraoperative scans was {approx}11.5 mGy for CBCT-guided thoracic vertebroplasty and {approx}23.2 mGy for lumbar vertebroplasty, with dose to staff at tableside reduced to {approx}1 min of fluoroscopy time ({approx}40-60 {mu}Sv), compared to 5-11 min for the conventional approach. Conclusions: Intraoperative CBCT using a high-performance mobile C-arm prototype demonstrates image quality suitable to guidance of spine surgery, with task-specific protocols providing an important basis for minimizing radiation dose, while maintaining image quality sufficient for surgical guidance. Images demonstrate a significant advance in spatial resolution and soft-tissue visibility, and CBCT guidance offers the potential to reduce fluoroscopy reliance, reducing cumulative dose to patient and staff. Integration with a surgical guidance system demonstrates precise tracking and visualization in up-to-date images (alleviating reliance on preoperative images only), including detection of errors or suboptimal surgical outcomes in the operating room.« less

  14. SPICE Module for the Satellite Orbit Analysis Program (SOAP)

    NASA Technical Reports Server (NTRS)

    Coggi, John; Carnright, Robert; Hildebrand, Claude

    2008-01-01

    A SPICE module for the Satellite Orbit Analysis Program (SOAP) precisely represents complex motion and maneuvers in an interactive, 3D animated environment with support for user-defined quantitative outputs. (SPICE stands for Spacecraft, Planet, Instrument, Camera-matrix, and Events). This module enables the SOAP software to exploit NASA mission ephemeris represented in the JPL Ancillary Information Facility (NAIF) SPICE formats. Ephemeris types supported include position, velocity, and orientation for spacecraft and planetary bodies including the Sun, planets, natural satellites, comets, and asteroids. Entire missions can now be imported into SOAP for 3D visualization, playback, and analysis. The SOAP analysis and display features can now leverage detailed mission files to offer the analyst both a numerically correct and aesthetically pleasing combination of results that can be varied to study many hypothetical scenarios. The software provides a modeling and simulation environment that can encompass a broad variety of problems using orbital prediction. For example, ground coverage analysis, communications analysis, power and thermal analysis, and 3D visualization that provide the user with insight into complex geometric relations are included. The SOAP SPICE module allows distributed science and engineering teams to share common mission models of known pedigree, which greatly reduces duplication of effort and the potential for error. The use of the software spans all phases of the space system lifecycle, from the study of future concepts to operations and anomaly analysis. It allows SOAP software to correctly position and orient all of the principal bodies of the Solar System within a single simulation session along with multiple spacecraft trajectories and the orientation of mission payloads. In addition to the 3D visualization, the user can define numeric variables and x-y plots to quantitatively assess metrics of interest.

  15. Web-based hybrid-dimensional Visualization and Exploration of Cytological Localization Scenarios.

    PubMed

    Kovanci, Gökhan; Ghaffar, Mehmood; Sommer, Björn

    2016-12-21

    The CELLmicrocosmos 4.2 PathwayIntegration (CmPI) is a tool which provides hybrid-dimensional visualization and analysis of intracellular protein and gene localizations in the context of a virtual 3D environment. This tool is developed based on Java/Java3D/JOGL and provides a standalone application compatible to all relevant operating systems. However, it requires Java and the local installation of the software. Here we present the prototype of an alternative web-based visualization approach, using Three.js and D3.js. In this way it is possible to visualize and explore CmPI-generated localization scenarios including networks mapped to 3D cell components by just providing a URL to a collaboration partner. This publication describes the integration of the different technologies – Three.js, D3.js and PHP – as well as an application case: a localization scenario of the citrate cycle. The CmPI web viewer is available at: http://CmPIweb.CELLmicrocosmos.org.

  16. Web-based hybrid-dimensional Visualization and Exploration of Cytological Localization Scenarios.

    PubMed

    Kovanci, Gökhan; Ghaffar, Mehmood; Sommer, Björn

    2016-10-01

    The CELLmicrocosmos 4.2 PathwayIntegration (CmPI) is a tool which provides hybriddimensional visualization and analysis of intracellular protein and gene localizations in the context of a virtual 3D environment. This tool is developed based on Java/Java3D/JOGL and provides a standalone application compatible to all relevant operating systems. However, it requires Java and the local installation of the software. Here we present the prototype of an alternative web-based visualization approach, using Three.js and D3.js. In this way it is possible to visualize and explore CmPI-generated localization scenarios including networks mapped to 3D cell components by just providing a URL to a collaboration partner. This publication describes the integration of the different technologies - Three.js, D3.js and PHP - as well as an application case: a localization scenario of the citrate cycle. The CmPI web viewer is available at: http://CmPIweb.CELLmicrocosmos.org.

  17. [Basic concept in computer assisted surgery].

    PubMed

    Merloz, Philippe; Wu, Hao

    2006-03-01

    To investigate application of medical digital imaging systems and computer technologies in orthopedics. The main computer-assisted surgery systems comprise the four following subcategories. (1) A collection and recording process for digital data on each patient, including preoperative images (CT scans, MRI, standard X-rays), intraoperative visualization (fluoroscopy, ultrasound), and intraoperative position and orientation of surgical instruments or bone sections (using 3D localises). Data merging based on the matching of preoperative imaging (CT scans, MRI, standard X-rays) and intraoperative visualization (anatomical landmarks, or bone surfaces digitized intraoperatively via 3D localiser; intraoperative ultrasound images processed for delineation of bone contours). (2) In cases where only intraoperative images are used for computer-assisted surgical navigation, the calibration of the intraoperative imaging system replaces the merged data system, which is then no longer necessary. (3) A system that provides aid in decision-making, so that the surgical approach is planned on basis of multimodal information: the interactive positioning of surgical instruments or bone sections transmitted via pre- or intraoperative images, display of elements to guide surgical navigation (direction, axis, orientation, length and diameter of a surgical instrument, impingement, etc. ). And (4) A system that monitors the surgical procedure, thereby ensuring that the optimal strategy defined at the preoperative stage is taken into account. It is possible that computer-assisted orthopedic surgery systems will enable surgeons to better assess the accuracy and reliability of the various operative techniques, an indispensable stage in the optimization of surgery.

  18. Occupational Survey Report AFSC 3E6X1; Operations Management

    DTIC Science & Technology

    2004-02-01

    Lt Bryan Pickett Feb 04 Occupational Survey Report AFSC 3E6X1 Operations Management I n t e g r i t y - S e r v i c e - E x c e l l e n c e...Report AFSC 3E6X1 Operations Management 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK...Nellis AFB NV (5) • Fairchild AFB WA (5) • Hurlburt Field FL (6) • Eglin AFB FL (4) • Ramstein AB (5) Operations Management 3E6X1 February 2004 (Approved

  19. How 3D immersive visualization is changing medical diagnostics

    NASA Astrophysics Data System (ADS)

    Koning, Anton H. J.

    2011-03-01

    Originally the only way to look inside the human body without opening it up was by means of two dimensional (2D) images obtained using X-ray equipment. The fact that human anatomy is inherently three dimensional leads to ambiguities in interpretation and problems of occlusion. Three dimensional (3D) imaging modalities such as CT, MRI and 3D ultrasound remove these drawbacks and are now part of routine medical care. While most hospitals 'have gone digital', meaning that the images are no longer printed on film, they are still being viewed on 2D screens. However, this way valuable depth information is lost, and some interactions become unnecessarily complex or even unfeasible. Using a virtual reality (VR) system to present volumetric data means that depth information is presented to the viewer and 3D interaction is made possible. At the Erasmus MC we have developed V-Scope, an immersive volume visualization system for visualizing a variety of (bio-)medical volumetric datasets, ranging from 3D ultrasound, via CT and MRI, to confocal microscopy, OPT and 3D electron-microscopy data. In this talk we will address the advantages of such a system for both medical diagnostics as well as for (bio)medical research.

  20. New Technologies for Acquisition and 3-D Visualization of Geophysical and Other Data Types Combined for Enhanced Understandings and Efficiencies of Oil and Gas Operations, Deepwater Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Thomson, J. A.; Gee, L. J.; George, T.

    2002-12-01

    This presentation shows results of a visualization method used to display and analyze multiple data types in a geospatially referenced three-dimensional (3-D) space. The integrated data types include sonar and seismic geophysical data, pipeline and geotechnical engineering data, and 3-D facilities models. Visualization of these data collectively in proper 3-D orientation yields insights and synergistic understandings not previously obtainable. Key technological components of the method are: 1) high-resolution geophysical data obtained using a newly developed autonomous underwater vehicle (AUV), 2) 3-D visualization software that delivers correctly positioned display of multiple data types and full 3-D flight navigation within the data space and 3) a highly immersive visualization environment (HIVE) where multidisciplinary teams can work collaboratively to develop enhanced understandings of geospatially complex data relationships. The initial study focused on an active deepwater development area in the Green Canyon protraction area, Gulf of Mexico. Here several planned production facilities required detailed, integrated data analysis for design and installation purposes. To meet the challenges of tight budgets and short timelines, an innovative new method was developed based on the combination of newly developed technologies. Key benefits of the method include enhanced understanding of geologically complex seabed topography and marine soils yielding safer and more efficient pipeline and facilities siting. Environmental benefits include rapid and precise identification of potential locations of protected deepwater biological communities for avoidance and protection during exploration and production operations. In addition, the method allows data presentation and transfer of learnings to an audience outside the scientific and engineering team. This includes regulatory personnel, marine archaeologists, industry partners and others.

  1. 3D localization of electrophysiology catheters from a single x-ray cone-beam projection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robert, Normand, E-mail: normand.robert@sri.utoronto.ca; Polack, George G.; Sethi, Benu

    2015-10-15

    Purpose: X-ray images allow the visualization of percutaneous devices such as catheters in real time but inherently lack depth information. The provision of 3D localization of these devices from cone beam x-ray projections would be advantageous for interventions such as electrophysiology (EP), whereby the operator needs to return a device to the same anatomical locations during the procedure. A method to achieve real-time 3D single view localization (SVL) of an object of known geometry from a single x-ray image is presented. SVL exploits the change in the magnification of an object as its distance from the x-ray source is varied.more » The x-ray projection of an object of interest is compared to a synthetic x-ray projection of a model of said object as its pose is varied. Methods: SVL was tested with a 3 mm spherical marker and an electrophysiology catheter. The effect of x-ray acquisition parameters on SVL was investigated. An independent reference localization method was developed to compare results when imaging a catheter translated via a computer controlled three-axes stage. SVL was also performed on clinical fluoroscopy image sequences. A commercial navigation system was used in some clinical image sequences for comparison. Results: SVL estimates exhibited little change as x-ray acquisition parameters were varied. The reproducibility of catheter position estimates in phantoms denoted by the standard deviations, (σ{sub x}, σ{sub y}, σ{sub z}) = (0.099 mm,  0.093 mm,  2.2 mm), where x and y are parallel to the detector plane and z is the distance from the x-ray source. Position estimates (x, y, z) exhibited a 4% systematic error (underestimation) when compared to the reference method. The authors demonstrated that EP catheters can be tracked in clinical fluoroscopic images. Conclusions: It has been shown that EP catheters can be localized in real time in phantoms and clinical images at fluoroscopic exposure rates. Further work is required to characterize performance in clinical images as well as the sensitivity to clinical image quality.« less

  2. Toward a 3D transrectal ultrasound system for verification of needle placement during high-dose-rate interstitial gynecologic brachytherapy.

    PubMed

    Rodgers, Jessica Robin; Surry, Kathleen; Leung, Eric; D'Souza, David; Fenster, Aaron

    2017-05-01

    Treatment for gynecologic cancers, such as cervical, recurrent endometrial, and vaginal malignancies, commonly includes external-beam radiation and brachytherapy. In high-dose-rate (HDR) interstitial gynecologic brachytherapy, radiation treatment is delivered via hollow needles that are typically inserted through a template on the perineum with a cylinder placed in the vagina for stability. Despite the need for precise needle placement to minimize complications and provide optimal treatment, there is no standard intra-operative image-guidance for this procedure. While some image-guidance techniques have been proposed, including magnetic resonance (MR) imaging, X-ray computed tomography (CT), and two-dimensional (2D) transrectal ultrasound (TRUS), these techniques have not been widely adopted. In order to provide intra-operative needle visualization and localization during interstitial brachytherapy, we have developed a three-dimensional (3D) TRUS system. This study describes the 3D TRUS system and reports on the system validation and results from a proof-of-concept patient study. To obtain a 3D TRUS image, the system rotates a conventional 2D endocavity transducer through 170 degrees in 12 s, reconstructing the 2D frames into a 3D image in real-time. The geometry of the reconstruction was validated using two geometric phantoms to ensure the accuracy of the linear measurements in each of the image coordinate directions and the volumetric accuracy of the system. An agar phantom including vaginal and rectal canals, as well as a model uterus and tumor, was designed and used to test the visualization and localization of the interstitial needles under idealized conditions by comparing the needles' positions between the 3D TRUS scan and a registered MR image. Five patients undergoing HDR interstitial gynecologic brachytherapy were imaged using the 3D TRUS system following the insertion of all needles. This image was manually, rigidly registered to the clinical postinsertion CT scan based on the vaginal cylinder of the needle template. The positions of the tips and the trajectory of the needle paths were compared between the modalities. The observed geometric errors of the system were ≤ 0.3 mm in each of the three coordinate planes of the 3D US image and the mean measured volumetric error was 0.10 cm 3 . In the phantom study, the mean needle tip difference was 1.54 ± 0.71 mm and the mean trajectory difference was 0.94 ± 0.89 degrees (n = 14). In the in vivo study, a total of 73 needles were placed, of which 88% of needles were visible and 79% of tips were identifiable in the 3D TRUS images. Six of the nine needles that were not visible were due to shadowing artifacts created by the presence of the vaginal cylinder of the needle template. The mean distance between corresponding needle tips in the two modalities was 3.82 ± 1.86 mm and the mean trajectory difference was 3.04 ± 1.63 degrees for the five patients. In this proof-of-concept study, the 3D TRUS system allowed for localization of needles not obscured by shadowing artifacts, providing a method for visualizing needles intra-operatively during HDR interstitial brachytherapy of gynecologic cancers and providing the potential for 3D image-guidance. © 2017 American Association of Physicists in Medicine.

  3. Investigating the Importance of Stereo Displays for Helicopter Landing Simulation

    DTIC Science & Technology

    2016-08-11

    visualization. The two instances of X Plane® were implemented using two separate PCs, each incorporating Intel i7 processors and Nvidia Quadro K4200... Nvidia GeForce GTX 680 graphics card was used to administer the stereo acuity and fusion range tests. The tests were displayed on an Asus VG278HE 3D...monitor with 1920x1080 pixels that was compatible with Nvidia 3D Vision2 and that used active shutter glasses. At a 1-m viewing distance, the

  4. Bedside assistance in freehand ultrasonic diagnosis by real-time visual feedback of 3D scatter diagram of pulsatile tissue-motion

    NASA Astrophysics Data System (ADS)

    Fukuzawa, M.; Kawata, K.; Nakamori, N.; Kitsunezuka, Y.

    2011-03-01

    By real-time visual feedback of 3D scatter diagram of pulsatile tissue-motion, freehand ultrasonic diagnosis of neonatal ischemic diseases has been assisted at the bedside. The 2D ultrasonic movie was taken with a conventional ultrasonic apparatus (ATL HDI5000) and ultrasonic probes of 5-7 MHz with the compact tilt-sensor to measure the probe orientation. The real-time 3D visualization was realized by developing an extended version of the PC-based visualization system. The software was originally developed on the DirectX platform and optimized with the streaming SIMD extensions. The 3D scatter diagram of the latest pulsatile tissues has been continuously generated and visualized as projection image with the ultrasonic movie in the current section more than 15 fps. It revealed the 3D structure of pulsatile tissues such as middle and posterior cerebral arteries, Willis ring and cerebellar arteries, in which pediatricians have great interests in the blood flow because asphyxiated and/or low-birth-weight neonates have a high risk of ischemic diseases such as hypoxic-ischemic encephalopathy and periventricular leukomalacia. Since the pulsatile tissue-motion is due to local blood flow, it can be concluded that the system developed in this work is very useful to assist freehand ultrasonic diagnosis of ischemic diseases in the neonatal cranium.

  5. An MR-based Model for Cardio-Respiratory Motion Compensation of Overlays in X-Ray Fluoroscopy

    PubMed Central

    Fischer, Peter; Faranesh, Anthony; Pohl, Thomas; Maier, Andreas; Rogers, Toby; Ratnayaka, Kanishka; Lederman, Robert; Hornegger, Joachim

    2017-01-01

    In X-ray fluoroscopy, static overlays are used to visualize soft tissue. We propose a system for cardiac and respiratory motion compensation of these overlays. It consists of a 3-D motion model created from real-time MR imaging. Multiple sagittal slices are acquired and retrospectively stacked to consistent 3-D volumes. Slice stacking considers cardiac information derived from the ECG and respiratory information extracted from the images. Additionally, temporal smoothness of the stacking is enhanced. Motion is estimated from the MR volumes using deformable 3-D/3-D registration. The motion model itself is a linear direct correspondence model using the same surrogate signals as slice stacking. In X-ray fluoroscopy, only the surrogate signals need to be extracted to apply the motion model and animate the overlay in real time. For evaluation, points are manually annotated in oblique MR slices and in contrast-enhanced X-ray images. The 2-D Euclidean distance of these points is reduced from 3.85 mm to 2.75 mm in MR and from 3.0 mm to 1.8 mm in X-ray compared to the static baseline. Furthermore, the motion-compensated overlays are shown qualitatively as images and videos. PMID:28692969

  6. Pelagic habitat visualization: the need for a third (and fourth) dimension: HabitatSpace

    USGS Publications Warehouse

    Beegle-Krause, C; Vance, Tiffany; Reusser, Debbie; Stuebe, David; Howlett, Eoin

    2009-01-01

    Habitat in open water is not simply a 2-D to 2.5-D surface such as the ocean bottom or the air-water interface. Rather, pelagic habitat is a 3-D volume of water that can change over time, leading us to the term habitat space. Visualization and analysis in 2-D is well supported with GIS tools, but a new tool was needed for visualization and analysis in four dimensions. Observational data (cruise profiles (xo, yo, z, to)), numerical circulation model fields (x,y,z,t), and trajectories (larval fish, 4-D line) need to be merged together in a meaningful way for visualization and analysis. As a first step toward this new framework, UNIDATA’s Integrated Data Viewer (IDV) has been used to create a set of tools for habitat analysis in 4-D. IDV was designed for 3-D+time geospatial data in the meteorological community. NetCDF JavaTM libraries allow the tool to read many file formats including remotely located data (e.g. data available via OPeNDAP ). With this project, IDV has been adapted for use in delineating habitat space for multiple fish species in the ocean. The ability to define and visualize boundaries of a water mass, which meets specific biologically relevant criteria (e.g., volume, connectedness, and inter-annual variability) based on model results and observational data, will allow managers to investigate the survival of individual year classes of commercially important fisheries. Better understanding of the survival of these year classes will lead to improved forecasting of fisheries recruitment.

  7. 3D visualization of the scoliotic spine: longitudinal studies, data acquisition, and radiation dosage constraints

    NASA Astrophysics Data System (ADS)

    Kalvin, Alan D.; Adler, Roy L.; Margulies, Joseph Y.; Tresser, Charles P.; Wu, Chai W.

    1999-05-01

    Decision making in the treatment of scoliosis is typically based on longitudinal studies that involve the imaging and visualization the progressive degeneration of a patient's spine over a period of years. Some patients will need surgery if their spinal deformation exceeds a certain degree of severity. Currently, surgeons rely on 2D measurements, obtained from x-rays, to quantify spinal deformation. Clearly working only with 2D measurements seriously limits the surgeon's ability to infer 3D spinal pathology. Standard CT scanning is not a practical solution for obtaining 3D spinal measurements of scoliotic patients. Because it would expose the patient to a prohibitively high dose of radiation. We have developed 2 new CT-based methods of 3D spinal visualization that produce 3D models of the spine by integrating a very small number of axial CT slices with data obtained from CT scout data. In the first method the scout data are converted to sinogram data, and then processed by a tomographic image reconstruction algorithm. In the second method, the vertebral boundaries are detected in the scout data, and these edges are then used as linear constraints to determine 2D convex hulls of the vertebrae.

  8. [Clinical analysis of real-time iris recognition guided LASIK with femtosecond laser flap creation for myopic astigmatism].

    PubMed

    Jie, Li-ming; Wang, Qian; Zheng, Lin

    2013-08-01

    To assess the safety, efficacy, stability and changes in cylindrical degree and axis after real-time iris recognition guided LASIK with femtosecond laser flap creation for the correction of myopic astigmatism. Retrospective case series. This observational case study comprised 136 patients (249 eyes) with myopic astigmatism in a 6-month trial. Patients were divided into 3 groups according to the pre-operative cylindrical degree: Group 1, -0.75 to -1.25 D, 106 eyes;Group 2, -1.50 to -2.25 D, 89 eyes and Group 3, -2.50 to -5.00 D, 54 eyes. They were also grouped by pre-operative astigmatism axis:Group A, with the rule astigmatism (WTRA), 156 eyes; Group B, against the rule astigmatism (ATRA), 64 eyes;Group C, oblique axis astigmatism, 29 eyes. After femtosecond laser flap created, real-time iris recognized excimer ablation was performed. The naked visual acuity, the best-corrected visual acuity, the degree and axis of astigmatism were analyzed and compared at 1, 3 and 6 months postoperatively. Static iris recognition detected that eye cyclotorsional misalignment was 2.37° ± 2.16°, dynamic iris recognition detected that the intraoperative cyclotorsional misalignment range was 0-4.3°. Six months after operation, the naked visual acuity was 0.5 or better in 100% cases. No eye lost ≥ 1 line of best spectacle-corrected visual acuity (BSCVA). Six months after operation, the naked vision of 227 eyes surpassed the BSCVA, and 87 eyes gained 1 line of BSCVA. The degree of astigmatism decreased from (-1.72 ± 0.77) D (pre-operation) to (-0.29 ± 0.25) D (post-operation). Six months after operation, WTRA from 157 eyes (pre-operation) decreased to 43 eyes (post-operation), ATRA from 63 eyes (pre-operation) decreased to 28 eyes (post-operation), oblique astigmatism increased from 29 eyes to 34 eyes and 144 eyes became non-astigmatism. The real-time iris recognition guided LASIK with femtosecond laser flap creation can compensate deviation from eye cyclotorsion, decrease iatrogenic astigmatism, and provides more precise treatment for the degree and axis of astigmatism .It is an effective and safe procedure for the treatment of myopic astigmatism.

  9. Solid object visualization of 3D ultrasound data

    NASA Astrophysics Data System (ADS)

    Nelson, Thomas R.; Bailey, Michael J.

    2000-04-01

    Visualization of volumetric medical data is challenging. Rapid-prototyping (RP) equipment producing solid object prototype models of computer generated structures is directly applicable to visualization of medical anatomic data. The purpose of this study was to develop methods for transferring 3D Ultrasound (3DUS) data to RP equipment for visualization of patient anatomy. 3DUS data were acquired using research and clinical scanning systems. Scaling information was preserved and the data were segmented using threshold and local operators to extract features of interest, converted from voxel raster coordinate format to a set of polygons representing an iso-surface and transferred to the RP machine to create a solid 3D object. Fabrication required 30 to 60 minutes depending on object size and complexity. After creation the model could be touched and viewed. A '3D visualization hardcopy device' has advantages for conveying spatial relations compared to visualization using computer display systems. The hardcopy model may be used for teaching or therapy planning. Objects may be produced at the exact dimension of the original object or scaled up (or down) to facilitate matching the viewers reference frame more optimally. RP models represent a useful means of communicating important information in a tangible fashion to patients and physicians.

  10. Software components for medical image visualization and surgical planning

    NASA Astrophysics Data System (ADS)

    Starreveld, Yves P.; Gobbi, David G.; Finnis, Kirk; Peters, Terence M.

    2001-05-01

    Purpose: The development of new applications in medical image visualization and surgical planning requires the completion of many common tasks such as image reading and re-sampling, segmentation, volume rendering, and surface display. Intra-operative use requires an interface to a tracking system and image registration, and the application requires basic, easy to understand user interface components. Rapid changes in computer and end-application hardware, as well as in operating systems and network environments make it desirable to have a hardware and operating system as an independent collection of reusable software components that can be assembled rapidly to prototype new applications. Methods: Using the OpenGL based Visualization Toolkit as a base, we have developed a set of components that implement the above mentioned tasks. The components are written in both C++ and Python, but all are accessible from Python, a byte compiled scripting language. The components have been used on the Red Hat Linux, Silicon Graphics Iris, Microsoft Windows, and Apple OS X platforms. Rigorous object-oriented software design methods have been applied to ensure hardware independence and a standard application programming interface (API). There are components to acquire, display, and register images from MRI, MRA, CT, Computed Rotational Angiography (CRA), Digital Subtraction Angiography (DSA), 2D and 3D ultrasound, video and physiological recordings. Interfaces to various tracking systems for intra-operative use have also been implemented. Results: The described components have been implemented and tested. To date they have been used to create image manipulation and viewing tools, a deep brain functional atlas, a 3D ultrasound acquisition and display platform, a prototype minimally invasive robotic coronary artery bypass graft planning system, a tracked neuro-endoscope guidance system and a frame-based stereotaxy neurosurgery planning tool. The frame-based stereotaxy module has been licensed and certified for use in a commercial image guidance system. Conclusions: It is feasible to encapsulate image manipulation and surgical guidance tasks in individual, reusable software modules. These modules allow for faster development of new applications. The strict application of object oriented software design methods allows individual components of such a system to make the transition from the research environment to a commercial one.

  11. Heavy metal staining, a comparative assessment of gadolinium chloride and osmium tetroxide for inner ear labyrinthine contrast enhancement using X-ray microtomography.

    PubMed

    Wong, Christopher C; Curthoys, Ian S; O'Leary, Stephen J; Jones, Allan S

    2013-01-01

    The use of both gadolinium chloride (GdCl(3)) and osmium tetroxide (OsO(4)) allowed for the visualization of the membranous labyrinth and other intralabyrinthine structures, at different intensities, as compared with the control sample. This initial comparison shows the advantages of GdCl(3) in radiological assessments and OsO(4) in more detailed anatomical studies and pathways of labyrinthine pathogenesis using X-ray microtomography (microCT). To assess an improved OsO(4) staining protocol and compare the staining affinities against GdCl(3). Guinea pig temporal bones were stained with either GdCl(3) (2% w/v) for 7 days or OsO(4) (2% w/v) for 3 days, and scanned in a microCT system. The post-scanned datasets were then assessed in a 3D rendering program. The enhanced soft tissue contrast as presented in the temporal bones stained with either GdCl(3) or OsO(4) allowed for the membranous labyrinth to be visualized throughout the whole specimen. GdCl(3)-stained specimens presented more defined contours of the bone profile in the radiographs, while OsO(4)-stained specimens provided more anatomical detail of individual intralabyrinthine structures, hence allowing spatial relationships to be visualized with ease in a 3D rendering context and 2D axial slice images.

  12. User Directed Tools for Exploiting Expert Knowledge in an Immersive Segmentation and Visualization Environment

    NASA Technical Reports Server (NTRS)

    Senger, Steven O.

    1998-01-01

    Volumetric data sets have become common in medicine and many sciences through technologies such as computed x-ray tomography (CT), magnetic resonance (MR), positron emission tomography (PET), confocal microscopy and 3D ultrasound. When presented with 2D images humans immediately and unconsciously begin a visual analysis of the scene. The viewer surveys the scene identifying significant landmarks and building an internal mental model of presented information. The identification of features is strongly influenced by the viewers expectations based upon their expert knowledge of what the image should contain. While not a conscious activity, the viewer makes a series of choices about how to interpret the scene. These choices occur in parallel with viewing the scene and effectively change the way the viewer sees the image. It is this interaction of viewing and choice which is the basis of many familiar visual illusions. This is especially important in the interpretation of medical images where it is the expert knowledge of the radiologist which interprets the image. For 3D data sets this interaction of view and choice is frustrated because choices must precede the visualization of the data set. It is not possible to visualize the data set with out making some initial choices which determine how the volume of data is presented to the eye. These choices include, view point orientation, region identification, color and opacity assignments. Further compounding the problem is the fact that these visualization choices are defined in terms of computer graphics as opposed to language of the experts knowledge. The long term goal of this project is to develop an environment where the user can interact with volumetric data sets using tools which promote the utilization of expert knowledge by incorporating visualization and choice into a tight computational loop. The tools will support activities involving the segmentation of structures, construction of surface meshes and local filtering of the data set. To conform to this environment tools should have several key attributes. First, they should be only rely on computations over a local neighborhood of the probe position. Second, they should operate iteratively over time converging towards a limit behavior. Third, they should adapt to user input modifying they operational parameters with time.

  13. A non-disruptive technology for robust 3D tool tracking for ultrasound-guided interventions.

    PubMed

    Mung, Jay; Vignon, Francois; Jain, Ameet

    2011-01-01

    In the past decade ultrasound (US) has become the preferred modality for a number of interventional procedures, offering excellent soft tissue visualization. The main limitation however is limited visualization of surgical tools. A new method is proposed for robust 3D tracking and US image enhancement of surgical tools under US guidance. Small US sensors are mounted on existing surgical tools. As the imager emits acoustic energy, the electrical signal from the sensor is analyzed to reconstruct its 3D coordinates. These coordinates can then be used for 3D surgical navigation, similar to current day tracking systems. A system with real-time 3D tool tracking and image enhancement was implemented on a commercial ultrasound scanner and 3D probe. Extensive water tank experiments with a tracked 0.2mm sensor show robust performance in a wide range of imaging conditions and tool position/orientations. The 3D tracking accuracy was 0.36 +/- 0.16mm throughout the imaging volume of 55 degrees x 27 degrees x 150mm. Additionally, the tool was successfully tracked inside a beating heart phantom. This paper proposes an image enhancement and tool tracking technology with sub-mm accuracy for US-guided interventions. The technology is non-disruptive, both in terms of existing clinical workflow and commercial considerations, showing promise for large scale clinical impact.

  14. Pollen structure visualization using high-resolution laboratory-based hard X-ray tomography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Qiong; Gluch, Jürgen; Krüger, Peter

    A laboratory-based X-ray microscope is used to investigate the 3D structure of unstained whole pollen grains. For the first time, high-resolution laboratory-based hard X-ray microscopy is applied to study pollen grains. Based on the efficient acquisition of statistically relevant information-rich images using Zernike phase contrast, both surface- and internal structures of pine pollen - including exine, intine and cellular structures - are clearly visualized. The specific volumes of these structures are calculated from the tomographic data. The systematic three-dimensional study of pollen grains provides morphological and structural information about taxonomic characters that are essential in palynology. Such studies have amore » direct impact on disciplines such as forestry, agriculture, horticulture, plant breeding and biodiversity. - Highlights: • The unstained whole pine pollen was visualized by high-resolution laboratory-based HXRM for the first time. • The comparison study of pollen grains by LM, SEM and high-resolution laboratory-based HXRM. • Phase contrast imaging provides significantly higher contrast of the raw images compared to absorption contrast imaging. • Surface and internal structure of the pine pollen including exine, intine and cellular structures are clearly visualized. • 3D volume data of unstained whole pollen grains are acquired and the specific volumes of the different layer are calculated.« less

  15. 3D coherent X-ray diffractive imaging of an Individual colloidal crystal grain

    NASA Astrophysics Data System (ADS)

    Shabalin, A.; Meijer, J.-M.; Sprung, M.; Petukhov, A. V.; Vartanyants, I. A.

    Self-assembled colloidal crystals represent an important model system to study nucleation phenomena and solid-solid phase transitions. They are attractive for applications in photonics and sensorics. We present results of a coherent x-ray diffractive imaging experiment performed on a single colloidal crystal grain. The full three-dimensional (3D) reciprocal space map measured by an azimuthal rotational scan contained several orders of Bragg reflections together with the coherent interference signal between them. Applying the iterative phase retrieval approach, the 3D structure of the crystal grain was reconstructed and positions of individual colloidal particles were resolved. We identified an exact stacking sequence of hexagonal close-packed layers including planar and linear defects. Our results open up a breakthrough in applications of coherent x-ray diffraction for visualization of the inner 3D structure of different mesoscopic materials, such as photonic crystals. Present address: University of California - San Diego, USA.

  16. Visual Sensitivities and Discriminations and Their Role in Aviation

    DTIC Science & Technology

    1987-10-30

    both x and y, Aimn can be found by using one quarter of the plane. Hence 2P0r far.eco(-keosy) Ahm = i coa nv (coa x + kcoa y)cos mx dx dy since f(z,y...198-201. 142. Neima D, LeBlanc R & Regan D (1984) Visual field defects in ocular hypertension and glaucoma . Arch Ophthalmol 102, 1042-5. 143. Regan D...Neima D (1984) Visual fatigue and VEPs in multiple sclerosis, glaucoma , ocular hypertension and Parkinson’s disease. J Neurol Neurosurg Psychiat 47

  17. High-resolution T1-weighted 3D real IR imaging of the temporal bone using triple-dose contrast material.

    PubMed

    Naganawa, Shinji; Koshikawa, Tokiko; Nakamura, Tatsuya; Fukatsu, Hiroshi; Ishigaki, Takeo; Aoki, Ikuo

    2003-12-01

    The small structures in the temporal bone are surrounded by bone and air. The objectives of this study were (a) to compare contrast-enhanced T1-weighted images acquired by fast spin-echo-based three-dimensional real inversion recovery (3D rIR) against those acquired by gradient echo-based 3D SPGR in the visualization of the enhancement of small structures in the temporal bone, and (b) to determine whether either 3D rIR or 3D SPGR is useful for visualizing enhancement of the cochlear lymph fluid. Seven healthy men (age range 27-46 years) volunteered to participate in this study. All MR imaging was performed using a dedicated bilateral quadrature surface phased-array coil for temporal bone imaging at 1.5 T (Visart EX, Toshiba, Tokyo, Japan). The 3D rIR images (TR/TE/TI: 1800 ms/10 ms/500 ms) and flow-compensated 3D SPGR images (TR/TE/FA: 23 ms/10 ms/25 degrees) were obtained with a reconstructed voxel size of 0.6 x 0.7 x 0.8 mm3. Images were acquired before and 1, 90, 180, and 270 min after the administration of triple-dose Gd-DTPA-BMA (0.3 mmol/kg). In post-contrast MR images, the degree of enhancement of the cochlear aqueduct, endolymphatic sac, subarcuate artery, geniculate ganglion of the facial nerve, and cochlear lymph fluid space was assessed by two radiologists. The degree of enhancement was scored as follows: 0 (no enhancement); 1 (slight enhancement); 2 (intermediate between 1 and 3); and 3 (enhancement similar to that of vessels). Enhancement scores for the endolymphatic sac, subarcuate artery, and geniculate ganglion were higher in 3D rIR than in 3D SPGR. Washout of enhancement in the endolymphatic sac appeared to be delayed compared with that in the subarcuate artery, suggesting that the enhancement in the endolymphatic sac may have been due in part to non-vascular tissue enhancement. Enhancement of the cochlear lymph space was not observed in any of the subjects in 3D rIR and 3D SPGR. The 3D rIR sequence may be more sensitive than the 3D SPGR sequence in visualizing the enhancement of small structures in the temporal bone; however, enhancement of the cochlear fluid space could not be visualized even with 3D rIR, triple-dose contrast, and dedicated coils at 1.5 T.

  18. Exploratory Climate Data Visualization and Analysis Using DV3D and UVCDAT

    NASA Technical Reports Server (NTRS)

    Maxwell, Thomas

    2012-01-01

    Earth system scientists are being inundated by an explosion of data generated by ever-increasing resolution in both global models and remote sensors. Advanced tools for accessing, analyzing, and visualizing very large and complex climate data are required to maintain rapid progress in Earth system research. To meet this need, NASA, in collaboration with the Ultra-scale Visualization Climate Data Analysis Tools (UVCOAT) consortium, is developing exploratory climate data analysis and visualization tools which provide data analysis capabilities for the Earth System Grid (ESG). This paper describes DV3D, a UV-COAT package that enables exploratory analysis of climate simulation and observation datasets. OV3D provides user-friendly interfaces for visualization and analysis of climate data at a level appropriate for scientists. It features workflow inte rfaces, interactive 40 data exploration, hyperwall and stereo visualization, automated provenance generation, and parallel task execution. DV30's integration with CDAT's climate data management system (COMS) and other climate data analysis tools provides a wide range of high performance climate data analysis operations. DV3D expands the scientists' toolbox by incorporating a suite of rich new exploratory visualization and analysis methods for addressing the complexity of climate datasets.

  19. First Clinical Applications of a High-Definition Three-Dimensional Exoscope in Pediatric Neurosurgery

    PubMed Central

    Munoz-Bendix, Christopher; Beseoglu, Kerim; Steiger, Hans-Jakob; Ahmadi, Sebastian A

    2018-01-01

    The ideal visualization tools in microneurosurgery should provide magnification, illumination, wide fields of view, ergonomics, and unobstructed access to the surgical field. The operative microscope was the predominant innovation in modern neurosurgery. Recently, a high-definition three-dimensional (3D) exoscope was developed. We describe the first applications in pediatric neurosurgery. The VITOM 3D exoscope (Karl Storz GmbH, Tuttlingen, Germany) was used in pediatric microneurosurgical operations, along with an OPMI PENTERO operative microscope (Carl Zeiss AG, Jena, Germany). Experiences were retrospectively evaluated with five-level Likert items regarding ease of preparation, image definition, magnification, illumination, field of view, ergonomics, accessibility of the surgical field, and general user-friendliness. Three operations were performed: supratentorial open biopsy in the supine position, infratentorial brain tumor resection in the park bench position, and myelomeningocele closure in the prone position. While preparation and image definition were rated equal for microscope and exoscope, the microscope’s field of view, illumination, and user-friendliness were considered superior, while the advantages of the exoscope were seen in ergonomics and the accessibility of the surgical field. No complications attributed to visualization mode occurred. In our experience, the VITOM 3D exoscope is an innovative visualization tool with advantages over the microscope in ergonomics and the accessibility of the surgical field. However, improvements were deemed necessary with regard to field of view, illumination, and user-friendliness. While the debate of a “perfect” visualization modality is influenced by personal preference, this novel visualization device has the potential to become a valuable tool in the neurosurgeon’s armamentarium. PMID:29581920

  20. First Clinical Applications of a High-Definition Three-Dimensional Exoscope in Pediatric Neurosurgery.

    PubMed

    Beez, Thomas; Munoz-Bendix, Christopher; Beseoglu, Kerim; Steiger, Hans-Jakob; Ahmadi, Sebastian A

    2018-01-24

    The ideal visualization tools in microneurosurgery should provide magnification, illumination, wide fields of view, ergonomics, and unobstructed access to the surgical field. The operative microscope was the predominant innovation in modern neurosurgery. Recently, a high-definition three-dimensional (3D) exoscope was developed. We describe the first applications in pediatric neurosurgery. The VITOM 3D exoscope (Karl Storz GmbH, Tuttlingen, Germany) was used in pediatric microneurosurgical operations, along with an OPMI PENTERO operative microscope (Carl Zeiss AG, Jena, Germany). Experiences were retrospectively evaluated with five-level Likert items regarding ease of preparation, image definition, magnification, illumination, field of view, ergonomics, accessibility of the surgical field, and general user-friendliness. Three operations were performed: supratentorial open biopsy in the supine position, infratentorial brain tumor resection in the park bench position, and myelomeningocele closure in the prone position. While preparation and image definition were rated equal for microscope and exoscope, the microscope's field of view, illumination, and user-friendliness were considered superior, while the advantages of the exoscope were seen in ergonomics and the accessibility of the surgical field. No complications attributed to visualization mode occurred. In our experience, the VITOM 3D exoscope is an innovative visualization tool with advantages over the microscope in ergonomics and the accessibility of the surgical field. However, improvements were deemed necessary with regard to field of view, illumination, and user-friendliness. While the debate of a "perfect" visualization modality is influenced by personal preference, this novel visualization device has the potential to become a valuable tool in the neurosurgeon's armamentarium.

  1. EarthServer - 3D Visualization on the Web

    NASA Astrophysics Data System (ADS)

    Wagner, Sebastian; Herzig, Pasquale; Bockholt, Ulrich; Jung, Yvonne; Behr, Johannes

    2013-04-01

    EarthServer (www.earthserver.eu), funded by the European Commission under its Seventh Framework Program, is a project to enable the management, access and exploration of massive, multi-dimensional datasets using Open GeoSpatial Consortium (OGC) query and processing language standards like WCS 2.0 and WCPS. To this end, a server/client architecture designed to handle Petabyte/Exabyte volumes of multi-dimensional data is being developed and deployed. As an important part of the EarthServer project, six Lighthouse Applications, major scientific data exploitation initiatives, are being established to make cross-domain, Earth Sciences related data repositories available in an open and unified manner, as service endpoints based on solutions and infrastructure developed within the project. Clients technology developed and deployed in EarthServer ranges from mobile and web clients to immersive virtual reality systems, all designed to interact with a physically and logically distributed server infrastructure using exclusively OGC standards. In this contribution, we would like to present our work on a web-based 3D visualization and interaction client for Earth Sciences data using only technology found in standard web browsers without requiring the user to install plugins or addons. Additionally, we are able to run the earth data visualization client on a wide range of different platforms with very different soft- and hardware requirements such as smart phones (e.g. iOS, Android), different desktop systems etc. High-quality, hardware-accelerated visualization of 3D and 4D content in standard web browsers can be realized now and we believe it will become more and more common to use this fast, lightweight and ubiquitous platform to provide insights into big datasets without requiring the user to set up a specialized client first. With that in mind, we will also point out some of the limitations we encountered using current web technologies. Underlying the EarthServer web client and on top of HTML5, WebGL and JavaScript we have developed the X3DOM framework (www.x3dom.org), which makes possible to embed declarative X3D scenegraphs, an ISO standard XML-based file format for representing 3D computer graphics, directly within HTML, thus enabling developers to rapidly design 3D content that blends seamlessly into HTML interfaces using Javascript. This approach (commonly referred to as a polyfill layer) is used to mimic native web browser support for declarative 3D content and is an important component in our web client architecture.

  2. [Application of 3D visualization technique in breast cancer surgery with immediate breast reconstruction using laparoscopically harvested pedicled latissimus dorsi muscle flap].

    PubMed

    Zhang, Pu-Sheng; Wang, Li-Kun; Luo, Yun-Feng; Shi, Fu-Jun; He, Lin-Yun; Zeng, Cheng-Bing; Zhang, Yu; Fang, Chi-Hua

    2017-08-20

    To study the value of 3D visualization technique in breast-preserving surgery for breast cancer with immediate breast reconstruction using laparoscopically harvested pedicled latissimus dorsi muscle flap. From January, 2015 to May, 2016, 30 patients with breast cancer underwent breast-preserving surgery with immediate breast reconstruction using pedicled latissimus dorsi muscle flap. The CT data of the arterial phase and venous phase were collected preoperatively and imported into the self-developed medical image 3D visualization system for image segmentation and 3D reconstruction. The 3D models were imported into the simulation surgery platform for virtual surgery to prepare for subsequent surgeries. The cosmetic outcomes of the patients were evaluated 6 months after the surgery. Another 18 patients with breast cancer who underwent laparoscopic latissimus dorsi muscle breast reconstruction without using 3D visualization technique from January to December, 2014 served as the control group. The data of the operative time, intraoperative blood loss and postoperative appearance of the breasts were analyzed. The reconstructed 3D model clearly displayed the anatomical structures of the breast, armpit, latissimus dorsi muscle and vessels and their anatomical relationship in all the 30 cases. Immediate breast reconstruction was performed successfully in all the cases with median operation time of 226 min (range, 210 to 420 min), a median blood loss of 95 mL (range, 73 to 132 mL). Evaluation of the appearance of the breast showed excellent results in 22 cases, good appearance in 6 cases and acceptable appearance in 2 cases. In the control group, the median operation time was 283 min (range, 256 to 313 min) and the median blood loss was 107 mL (range, 79 to 147 mL) with excellent appearance of the breasts in 10 cases, good appearance in 4 cases and acceptable appearance in 4 cases. 3D reconstruction technique can clearly display the morphology of the latissimus dorsi and the thoracic dorsal artery, allows calculation of the volume of the breast and the latissimus dorsi, and helps in defining the scope of resection of the latissimus dorsi to avoid injuries of the pedicled vessels. This technique also helps to shorten the operation time, reduce intraoperative bleeding, and improve the appearance of the reconstructed breast using pedicled latissimus dorsi muscle flap.

  3. A topological framework for interactive queries on 3D models in the Web.

    PubMed

    Figueiredo, Mauro; Rodrigues, José I; Silvestre, Ivo; Veiga-Pires, Cristina

    2014-01-01

    Several technologies exist to create 3D content for the web. With X3D, WebGL, and X3DOM, it is possible to visualize and interact with 3D models in a web browser. Frequently, three-dimensional objects are stored using the X3D file format for the web. However, there is no explicit topological information, which makes it difficult to design fast algorithms for applications that require adjacency and incidence data. This paper presents a new open source toolkit TopTri (Topological model for Triangle meshes) for Web3D servers that builds the topological model for triangular meshes of manifold or nonmanifold models. Web3D client applications using this toolkit make queries to the web server to get adjacent and incidence information of vertices, edges, and faces. This paper shows the application of the topological information to get minimal local points and iso-lines in a 3D mesh in a web browser. As an application, we present also the interactive identification of stalactites in a cave chamber in a 3D web browser. Several tests show that even for large triangular meshes with millions of triangles, the adjacency and incidence information is returned in real time making the presented toolkit appropriate for interactive Web3D applications.

  4. A Topological Framework for Interactive Queries on 3D Models in the Web

    PubMed Central

    Figueiredo, Mauro; Rodrigues, José I.; Silvestre, Ivo; Veiga-Pires, Cristina

    2014-01-01

    Several technologies exist to create 3D content for the web. With X3D, WebGL, and X3DOM, it is possible to visualize and interact with 3D models in a web browser. Frequently, three-dimensional objects are stored using the X3D file format for the web. However, there is no explicit topological information, which makes it difficult to design fast algorithms for applications that require adjacency and incidence data. This paper presents a new open source toolkit TopTri (Topological model for Triangle meshes) for Web3D servers that builds the topological model for triangular meshes of manifold or nonmanifold models. Web3D client applications using this toolkit make queries to the web server to get adjacent and incidence information of vertices, edges, and faces. This paper shows the application of the topological information to get minimal local points and iso-lines in a 3D mesh in a web browser. As an application, we present also the interactive identification of stalactites in a cave chamber in a 3D web browser. Several tests show that even for large triangular meshes with millions of triangles, the adjacency and incidence information is returned in real time making the presented toolkit appropriate for interactive Web3D applications. PMID:24977236

  5. A novel cost-effective computer-assisted imaging technology for accurate placement of thoracic pedicle screws.

    PubMed

    Abe, Yuichiro; Ito, Manabu; Abumi, Kuniyoshi; Kotani, Yoshihisa; Sudo, Hideki; Minami, Akio

    2011-11-01

    Use of computer-assisted spine surgery (CASS) technologies, such as navigation systems, to improve the accuracy of pedicle screw (PS) placement is increasingly popular. Despite of their benefits, previous CASS systems are too expensive to be ubiquitously employed, and more affordable and portable systems are desirable. The aim of this study was to introduce a novel and affordable computer-assisted technique that 3-dimensionally visualizes anatomical features of the pedicles and assists in PS insertion. The authors have termed this the 3D-visual guidance technique for inserting pedicle screws (3D-VG TIPS). The 3D-VG technique for placing PSs requires only a consumer-class computer with an inexpensive 3D DICOM viewer; other special equipment is unnecessary. Preoperative CT data of the spine were collected for each patient using the 3D-VG TIPS. In this technique, the anatomical axis of each pedicle can be analyzed by volume-rendered 3D models, as with existing navigation systems, and both the ideal entry point and the trajectory of each PS can be visualized on the surface of 3D-rendered images. Intraoperative guidance slides are made from these images and displayed on a TV monitor in the operating room. The surgeon can insert PSs according to these guidance slides. The authors enrolled 30 patients with adolescent idiopathic scoliosis (AIS) who underwent posterior fusion with segmental screw fixation for validation of this technique. The novel technique allowed surgeons, from office or home, to evaluate the precise anatomy of each pedicle and the risks of screw misplacement, and to perform 3D preoperative planning for screw placement on their own computer. Looking at both 3D guidance images on a TV monitor and the bony structures of the posterior elements in each patient in the operating theater, surgeons were able to determine the best entry point for each PS with ease and confidence. Using the current technique, the screw malposition rate was 4.5% in the thoracic region in corrective surgery for AIS. The authors found that 3D-VG TIPS worked on a consumer-class computer and easily visualized the ideal entry point and trajectory of PSs in any operating theater without costly special equipment. This new technique is suitable for preoperative planning and intraoperative guidance when performing reconstructive surgery with PSs.

  6. Mapping detailed 3D information onto high resolution SAR signatures

    NASA Astrophysics Data System (ADS)

    Anglberger, H.; Speck, R.

    2017-05-01

    Due to challenges in the visual interpretation of radar signatures or in the subsequent information extraction, a fusion with other data sources can be beneficial. The most accurate basis for a fusion of any kind of remote sensing data is the mapping of the acquired 2D image space onto the true 3D geometry of the scenery. In the case of radar images this is a challenging task because the coordinate system is based on the measured range which causes ambiguous regions due to layover effects. This paper describes a method that accurately maps the detailed 3D information of a scene to the slantrange-based coordinate system of imaging radars. Due to this mapping all the contributing geometrical parts of one resolution cell can be determined in 3D space. The proposed method is highly efficient, because computationally expensive operations can be directly performed on graphics card hardware. The described approach builds a perfect basis for sophisticated methods to extract data from multiple complimentary sensors like from radar and optical images, especially because true 3D information from whole cities will be available in the near future. The performance of the developed methods will be demonstrated with high resolution radar data acquired by the space-borne SAR-sensor TerraSAR-X.

  7. Recent developments in stereoscopic and holographic 3D display technologies

    NASA Astrophysics Data System (ADS)

    Sarma, Kalluri

    2014-06-01

    Currently, there is increasing interest in the development of high performance 3D display technologies to support a variety of applications including medical imaging, scientific visualization, gaming, education, entertainment, air traffic control and remote operations in 3D environments. In this paper we will review the attributes of the various 3D display technologies including stereoscopic and holographic 3D, human factors issues of stereoscopic 3D, the challenges in realizing Holographic 3D displays and the recent progress in these technologies.

  8. Application of advanced virtual reality and 3D computer assisted technologies in tele-3D-computer assisted surgery in rhinology.

    PubMed

    Klapan, Ivica; Vranjes, Zeljko; Prgomet, Drago; Lukinović, Juraj

    2008-03-01

    The real-time requirement means that the simulation should be able to follow the actions of the user that may be moving in the virtual environment. The computer system should also store in its memory a three-dimensional (3D) model of the virtual environment. In that case a real-time virtual reality system will update the 3D graphic visualization as the user moves, so that up-to-date visualization is always shown on the computer screen. Upon completion of the tele-operation, the surgeon compares the preoperative and postoperative images and models of the operative field, and studies video records of the procedure itself Using intraoperative records, animated images of the real tele-procedure performed can be designed. Virtual surgery offers the possibility of preoperative planning in rhinology. The intraoperative use of computer in real time requires development of appropriate hardware and software to connect medical instrumentarium with the computer and to operate the computer by thus connected instrumentarium and sophisticated multimedia interfaces.

  9. Employing Virtual Humans for Education and Training in X3D/VRML Worlds

    ERIC Educational Resources Information Center

    Ieronutti, Lucio; Chittaro, Luca

    2007-01-01

    Web-based education and training provides a new paradigm for imparting knowledge; students can access the learning material anytime by operating remotely from any location. Web3D open standards, such as X3D and VRML, support Web-based delivery of Educational Virtual Environments (EVEs). EVEs have a great potential for learning and training…

  10. Comparison of visual acuity of the patients on the first day after sub-Bowman keratomileusis or laser in situ keratomileusis.

    PubMed

    Zhao, Wei; Wu, Ting; Dong, Ze-Hong; Feng, Jie; Ren, Yu-Feng; Wang, Yu-Sheng

    2016-01-01

    To compare recovery of the visual acuity in patients one day after sub-Bowman keratomileusis (SBK) or laser in situ keratomileusis (LASIK). Data from 5923 eyes in 2968 patients that received LASIK (2755 eyes) or SBK (3168 eyes) were retrospectively analyzed. The eyes were divided into 4 groups according to preoperative spherical equivalent: between -12.00 to -9.00 D, extremely high myopia (n=396, including 192 and 204 in SBK and LASIK groups, respectively); -9.00 to -6.00 D, high myopia (n=1822, including 991 and 831 in SBK and LASIK groups, respectively), -6.00 to -3.00 D, moderate myopia (n=3071, including 1658 and 1413 in SBK and LASIK groups, respectively), and -3.00 to 0.00 D, low myopia (n=634, including 327 and 307 in SBK and LASIK groups, respectively). Uncorrected logMAR visual acuity values of patients were assessed under standard natural light. Analysis of variance was used for comparisons among different groups. Uncorrected visual acuity values were 0.0115±0.1051 and 0.0466±0.1477 at day 1 after operation for patients receiving SBK and LASIK, respectively (P<0.01); visual acuity values of 0.1854±0.1842, 0.0615±0.1326, -0.0033±0.0978, and -0.0164±0.0972 were obtained for patients in the extremely high, high, moderate, and low myopia groups, respectively (P<0.01). In addition, significant differences in visual acuity at day 1 after operation were found between patients receiving SBK and LASIK in each myopia subgroup. Compared with LASIK, SBK is safer and more effective, with faster recovery. Therefore, SBK is more likely to be accepted by patients than LASIK for better uncorrected visual acuity the day following operation.

  11. DataViewer3D: An Open-Source, Cross-Platform Multi-Modal Neuroimaging Data Visualization Tool

    PubMed Central

    Gouws, André; Woods, Will; Millman, Rebecca; Morland, Antony; Green, Gary

    2008-01-01

    Integration and display of results from multiple neuroimaging modalities [e.g. magnetic resonance imaging (MRI), magnetoencephalography, EEG] relies on display of a diverse range of data within a common, defined coordinate frame. DataViewer3D (DV3D) is a multi-modal imaging data visualization tool offering a cross-platform, open-source solution to simultaneous data overlay visualization requirements of imaging studies. While DV3D is primarily a visualization tool, the package allows an analysis approach where results from one imaging modality can guide comparative analysis of another modality in a single coordinate space. DV3D is built on Python, a dynamic object-oriented programming language with support for integration of modular toolkits, and development of cross-platform software for neuroimaging. DV3D harnesses the power of the Visualization Toolkit (VTK) for two-dimensional (2D) and 3D rendering, calling VTK's low level C++ functions from Python. Users interact with data via an intuitive interface that uses Python to bind wxWidgets, which in turn calls the user's operating system dialogs and graphical user interface tools. DV3D currently supports NIfTI-1, ANALYZE™ and DICOM formats for MRI data display (including statistical data overlay). Formats for other data types are supported. The modularity of DV3D and ease of use of Python allows rapid integration of additional format support and user development. DV3D has been tested on Mac OSX, RedHat Linux and Microsoft Windows XP. DV3D is offered for free download with an extensive set of tutorial resources and example data. PMID:19352444

  12. SAVA 3: A testbed for integration and control of visual processes

    NASA Technical Reports Server (NTRS)

    Crowley, James L.; Christensen, Henrik

    1994-01-01

    The development of an experimental test-bed to investigate the integration and control of perception in a continuously operating vision system is described. The test-bed integrates a 12 axis robotic stereo camera head mounted on a mobile robot, dedicated computer boards for real-time image acquisition and processing, and a distributed system for image description. The architecture was designed to: (1) be continuously operating, (2) integrate software contributions from geographically dispersed laboratories, (3) integrate description of the environment with 2D measurements, 3D models, and recognition of objects, (4) capable of supporting diverse experiments in gaze control, visual servoing, navigation, and object surveillance, and (5) dynamically reconfiguarable.

  13. A mapping of an ensemble of mitochondrial sequences for various organisms into 3D space based on the word composition.

    PubMed

    Aita, Takuyo; Nishigaki, Koichi

    2012-11-01

    To visualize a bird's-eye view of an ensemble of mitochondrial genome sequences for various species, we recently developed a novel method of mapping a biological sequence ensemble into Three-Dimensional (3D) vector space. First, we represented a biological sequence of a species s by a word-composition vector x(s), where its length [absolute value]x(s)[absolute value] represents the sequence length, and its unit vector x(s)/[absolute value]x(s)[absolute value] represents the relative composition of the K-tuple words through the sequence and the size of the dimension, N=4(K), is the number of all possible words with the length of K. Second, we mapped the vector x(s) to the 3D position vector y(s), based on the two following simple principles: (1) [absolute value]y(s)[absolute value]=[absolute value]x(s)[absolute value] and (2) the angle between y(s) and y(t) maximally correlates with the angle between x(s) and x(t). The mitochondrial genome sequences for 311 species, including 177 Animalia, 85 Fungi and 49 Green plants, were mapped into 3D space by using K=7. The mapping was successful because the angles between vectors before and after the mapping highly correlated with each other (correlation coefficients were 0.92-0.97). Interestingly, the Animalia kingdom is distributed along a single arc belt (just like the Milky Way on a Celestial Globe), and the Fungi and Green plant kingdoms are distributed in a similar arc belt. These two arc belts intersect at their respective middle regions and form a cross structure just like a jet aircraft fuselage and its wings. This new mapping method will allow researchers to intuitively interpret the visual information presented in the maps in a highly effective manner. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Volumetric 3D Display System with Static Screen

    NASA Technical Reports Server (NTRS)

    Geng, Jason

    2011-01-01

    Current display technology has relied on flat, 2D screens that cannot truly convey the third dimension of visual information: depth. In contrast to conventional visualization that is primarily based on 2D flat screens, the volumetric 3D display possesses a true 3D display volume, and places physically each 3D voxel in displayed 3D images at the true 3D (x,y,z) spatial position. Each voxel, analogous to a pixel in a 2D image, emits light from that position to form a real 3D image in the eyes of the viewers. Such true volumetric 3D display technology provides both physiological (accommodation, convergence, binocular disparity, and motion parallax) and psychological (image size, linear perspective, shading, brightness, etc.) depth cues to human visual systems to help in the perception of 3D objects. In a volumetric 3D display, viewers can watch the displayed 3D images from a completely 360 view without using any special eyewear. The volumetric 3D display techniques may lead to a quantum leap in information display technology and can dramatically change the ways humans interact with computers, which can lead to significant improvements in the efficiency of learning and knowledge management processes. Within a block of glass, a large amount of tiny dots of voxels are created by using a recently available machining technique called laser subsurface engraving (LSE). The LSE is able to produce tiny physical crack points (as small as 0.05 mm in diameter) at any (x,y,z) location within the cube of transparent material. The crack dots, when illuminated by a light source, scatter the light around and form visible voxels within the 3D volume. The locations of these tiny voxels are strategically determined such that each can be illuminated by a light ray from a high-resolution digital mirror device (DMD) light engine. The distribution of these voxels occupies the full display volume within the static 3D glass screen. This design eliminates any moving screen seen in previous approaches, so there is no image jitter, and has an inherent parallel mechanism for 3D voxel addressing. High spatial resolution is possible with a full color display being easy to implement. The system is low-cost and low-maintenance.

  15. The Effect of Break Edge Configuration on the Aerodynamics of Anti-Ice Jet Flow

    NASA Astrophysics Data System (ADS)

    Tatar, V.; Yildizay, H.; Aras, H.

    2015-05-01

    One of the components of a turboprop gas turbine engine is the Front Bearing Structure (FBS) which leads air into the compressor. FBS directly encounters with ambient air, as a consequence ice accretion may occur on its static vanes. There are several aerodynamic parameters which should be considered in the design of anti-icing system of FBS, such as diameter, position, exit angle of discharge holes, etc. This research focuses on the effects of break edge configuration over anti-ice jet flow. Break edge operation is a process which is applied to the hole in order to avoid sharp edges which cause high stress concentration. Numerical analyses and flow visualization test have been conducted. Four different break edge configurations were used for this investigation; without break edge, 0.35xD, 74xD, 0.87xD. Three mainstream flow conditions at the inlet of the channel are defined; 10m/s, 20 m/s and 40 m/s. Shear stresses are extracted from numerical analyses near the trailing edge of pressure surface where ice may occur under icing conditions. A specific flow visualization method was used for the experimental study. Vane surface near the trailing edge was dyed and thinner was injected into anti-ice jet flow in order to remove dye from the vane surface. Hence, film effect on the surface could be computed for each testing condition. Thickness of the dye removal area of each case was examined. The results show noticeable effects of break edge operation on jet flow, and the air film effectiveness decreases when mainstream inlet velocity decreases.

  16. Surgical planning for radical prostatectomies using three-dimensional visualization and a virtual reality display system

    NASA Astrophysics Data System (ADS)

    Kay, Paul A.; Robb, Richard A.; King, Bernard F.; Myers, R. P.; Camp, Jon J.

    1995-04-01

    Thousands of radical prostatectomies for prostate cancer are performed each year. Radical prostatectomy is a challenging procedure due to anatomical variability and the adjacency of critical structures, including the external urinary sphincter and neurovascular bundles that subserve erectile function. Because of this, there are significant risks of urinary incontinence and impotence following this procedure. Preoperative interaction with three-dimensional visualization of the important anatomical structures might allow the surgeon to understand important individual anatomical relationships of patients. Such understanding might decrease the rate of morbidities, especially for surgeons in training. Patient specific anatomic data can be obtained from preoperative 3D MRI diagnostic imaging examinations of the prostate gland utilizing endorectal coils and phased array multicoils. The volumes of the important structures can then be segmented using interactive image editing tools and then displayed using 3-D surface rendering algorithms on standard work stations. Anatomic relationships can be visualized using surface displays and 3-D colorwash and transparency to allow internal visualization of hidden structures. Preoperatively a surgeon and radiologist can interactively manipulate the 3-D visualizations. Important anatomical relationships can better be visualized and used to plan the surgery. Postoperatively the 3-D displays can be compared to actual surgical experience and pathologic data. Patients can then be followed to assess the incidence of morbidities. More advanced approaches to visualize these anatomical structures in support of surgical planning will be implemented on virtual reality (VR) display systems. Such realistic displays are `immersive,' and allow surgeons to simultaneously see and manipulate the anatomy, to plan the procedure and to rehearse it in a realistic way. Ultimately the VR systems will be implemented in the operating room (OR) to assist the surgeon in conducting the surgery. Such an implementation will bring to the OR all of the pre-surgical planning data and rehearsal experience in synchrony with the actual patient and operation to optimize the effectiveness and outcome of the procedure.

  17. New generation of 3D desktop computer interfaces

    NASA Astrophysics Data System (ADS)

    Skerjanc, Robert; Pastoor, Siegmund

    1997-05-01

    Today's computer interfaces use 2-D displays showing windows, icons and menus and support mouse interactions for handling programs and data files. The interface metaphor is that of a writing desk with (partly) overlapping sheets of documents placed on its top. Recent advances in the development of 3-D display technology give the opportunity to take the interface concept a radical stage further by breaking the design limits of the desktop metaphor. The major advantage of the envisioned 'application space' is, that it offers an additional, immediately perceptible dimension to clearly and constantly visualize the structure and current state of interrelations between documents, videos, application programs and networked systems. In this context, we describe the development of a visual operating system (VOS). Under VOS, applications appear as objects in 3-D space. Users can (graphically connect selected objects to enable communication between the respective applications. VOS includes a general concept of visual and object oriented programming for tasks ranging from, e.g., low-level programming up to high-level application configuration. In order to enable practical operation in an office or at home for many hours, the system should be very comfortable to use. Since typical 3-D equipment used, e.g., in virtual-reality applications (head-mounted displays, data gloves) is rather cumbersome and straining, we suggest to use off-head displays and contact-free interaction techniques. In this article, we introduce an autostereoscopic 3-D display and connected video based interaction techniques which allow viewpoint-depending imaging (by head tracking) and visually controlled modification of data objects and links (by gaze tracking, e.g., to pick, 3-D objects just by looking at them).

  18. Estimation and Detection with Chaotic Systems

    DTIC Science & Technology

    1994-02-01

    125 For each nonsingular transformation f: X - X on (X, /3, I), there is a unique operator Pf: Ll(/) Ll(p) known as the Frobenius - Perron operator which...satisfies lB Pf (p(x)) d.(x) = J (B) p(x) dl(x) (6.10) for each B E and p E L(u) [50, 55]. This rather abstract definition of the Frobenius - Perron ... Frobenius - Perron operator for the n-fold composition of the transformation f is the same as the n-fold composition of the Frobenius - Perron operator for f. As

  19. The Flatworld Simulation Control Architecture (FSCA): A Framework for Scalable Immersive Visualization Systems

    DTIC Science & Technology

    2004-12-01

    handling using the X10 home automation protocol. Each 3D graphics client renders its scene according to an assigned virtual camera position. By having...control protocol. DMX is a versatile and robust framework which overcomes limitations of the X10 home automation protocol which we are currently using

  20. Visualization of x-ray computer tomography using computer-generated holography

    NASA Astrophysics Data System (ADS)

    Daibo, Masahiro; Tayama, Norio

    1998-09-01

    The theory converted from x-ray projection data to the hologram directly by combining the computer tomography (CT) with the computer generated hologram (CGH), is proposed. The purpose of this study is to offer the theory for realizing the all- electronic and high-speed seeing through 3D visualization system, which is for the application to medical diagnosis and non- destructive testing. First, the CT is expressed using the pseudo- inverse matrix which is obtained by the singular value decomposition. CGH is expressed in the matrix style. Next, `projection to hologram conversion' (PTHC) matrix is calculated by the multiplication of phase matrix of CGH with pseudo-inverse matrix of the CT. Finally, the projection vector is converted to the hologram vector directly, by multiplication of the PTHC matrix with the projection vector. Incorporating holographic analog computation into CT reconstruction, it becomes possible that the calculation amount is drastically reduced. We demonstrate the CT cross section which is reconstituted by He-Ne laser in the 3D space from the real x-ray projection data acquired by x-ray television equipment, using our direct conversion technique.

  1. Thoracic cavity definition for 3D PET/CT analysis and visualization.

    PubMed

    Cheirsilp, Ronnarit; Bascom, Rebecca; Allen, Thomas W; Higgins, William E

    2015-07-01

    X-ray computed tomography (CT) and positron emission tomography (PET) serve as the standard imaging modalities for lung-cancer management. CT gives anatomical details on diagnostic regions of interest (ROIs), while PET gives highly specific functional information. During the lung-cancer management process, a patient receives a co-registered whole-body PET/CT scan pair and a dedicated high-resolution chest CT scan. With these data, multimodal PET/CT ROI information can be gleaned to facilitate disease management. Effective image segmentation of the thoracic cavity, however, is needed to focus attention on the central chest. We present an automatic method for thoracic cavity segmentation from 3D CT scans. We then demonstrate how the method facilitates 3D ROI localization and visualization in patient multimodal imaging studies. Our segmentation method draws upon digital topological and morphological operations, active-contour analysis, and key organ landmarks. Using a large patient database, the method showed high agreement to ground-truth regions, with a mean coverage=99.2% and leakage=0.52%. Furthermore, it enabled extremely fast computation. For PET/CT lesion analysis, the segmentation method reduced ROI search space by 97.7% for a whole-body scan, or nearly 3 times greater than that achieved by a lung mask. Despite this reduction, we achieved 100% true-positive ROI detection, while also reducing the false-positive (FP) detection rate by >5 times over that achieved with a lung mask. Finally, the method greatly improved PET/CT visualization by eliminating false PET-avid obscurations arising from the heart, bones, and liver. In particular, PET MIP views and fused PET/CT renderings depicted unprecedented clarity of the lesions and neighboring anatomical structures truly relevant to lung-cancer assessment. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Thoracic Cavity Definition for 3D PET/CT Analysis and Visualization

    PubMed Central

    Cheirsilp, Ronnarit; Bascom, Rebecca; Allen, Thomas W.; Higgins, William E.

    2015-01-01

    X-ray computed tomography (CT) and positron emission tomography (PET) serve as the standard imaging modalities for lung-cancer management. CT gives anatomical detail on diagnostic regions of interest (ROIs), while PET gives highly specific functional information. During the lung-cancer management process, a patient receives a co-registered whole-body PET/CT scan pair and a dedicated high-resolution chest CT scan. With these data, multimodal PET/CT ROI information can be gleaned to facilitate disease management. Effective image segmentation of the thoracic cavity, however, is needed to focus attention on the central chest. We present an automatic method for thoracic cavity segmentation from 3D CT scans. We then demonstrate how the method facilitates 3D ROI localization and visualization in patient multimodal imaging studies. Our segmentation method draws upon digital topological and morphological operations, active-contour analysis, and key organ landmarks. Using a large patient database, the method showed high agreement to ground-truth regions, with a mean coverage = 99.2% and leakage = 0.52%. Furthermore, it enabled extremely fast computation. For PET/CT lesion analysis, the segmentation method reduced ROI search space by 97.7% for a whole-body scan, or nearly 3 times greater than that achieved by a lung mask. Despite this reduction, we achieved 100% true-positive ROI detection, while also reducing the false-positive (FP) detection rate by >5 times over that achieved with a lung mask. Finally, the method greatly improved PET/CT visualization by eliminating false PET-avid obscurations arising from the heart, bones, and liver. In particular, PET MIP views and fused PET/CT renderings depicted unprecedented clarity of the lesions and neighboring anatomical structures truly relevant to lung-cancer assessment. PMID:25957746

  3. 3D interactive surgical visualization system using mobile spatial information acquisition and autostereoscopic display.

    PubMed

    Fan, Zhencheng; Weng, Yitong; Chen, Guowen; Liao, Hongen

    2017-07-01

    Three-dimensional (3D) visualization of preoperative and intraoperative medical information becomes more and more important in minimally invasive surgery. We develop a 3D interactive surgical visualization system using mobile spatial information acquisition and autostereoscopic display for surgeons to observe surgical target intuitively. The spatial information of regions of interest (ROIs) is captured by the mobile device and transferred to a server for further image processing. Triangular patches of intraoperative data with texture are calculated with a dimension-reduced triangulation algorithm and a projection-weighted mapping algorithm. A point cloud selection-based warm-start iterative closest point (ICP) algorithm is also developed for fusion of the reconstructed 3D intraoperative image and the preoperative image. The fusion images are rendered for 3D autostereoscopic display using integral videography (IV) technology. Moreover, 3D visualization of medical image corresponding to observer's viewing direction is updated automatically using mutual information registration method. Experimental results show that the spatial position error between the IV-based 3D autostereoscopic fusion image and the actual object was 0.38±0.92mm (n=5). The system can be utilized in telemedicine, operating education, surgical planning, navigation, etc. to acquire spatial information conveniently and display surgical information intuitively. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. 4D microscope-integrated OCT improves accuracy of ophthalmic surgical maneuvers

    NASA Astrophysics Data System (ADS)

    Carrasco-Zevallos, Oscar; Keller, Brenton; Viehland, Christian; Shen, Liangbo; Todorich, Bozho; Shieh, Christine; Kuo, Anthony; Toth, Cynthia; Izatt, Joseph A.

    2016-03-01

    Ophthalmic surgeons manipulate micron-scale tissues using stereopsis through an operating microscope and instrument shadowing for depth perception. While ophthalmic microsurgery has benefitted from rapid advances in instrumentation and techniques, the basic principles of the stereo operating microscope have not changed since the 1930's. Optical Coherence Tomography (OCT) has revolutionized ophthalmic imaging and is now the gold standard for preoperative and postoperative evaluation of most retinal and many corneal procedures. We and others have developed initial microscope-integrated OCT (MIOCT) systems for concurrent OCT and operating microscope imaging, but these are limited to 2D real-time imaging and require offline post-processing for 3D rendering and visualization. Our previously presented 4D MIOCT system can record and display the 3D surgical field stereoscopically through the microscope oculars using a dual-channel heads-up display (HUD) at up to 10 micron-scale volumes per second. In this work, we show that 4D MIOCT guidance improves the accuracy of depth-based microsurgical maneuvers (with statistical significance) in mock surgery trials in a wet lab environment. Additionally, 4D MIOCT was successfully performed in 38/45 (84%) posterior and 14/14 (100%) anterior eye human surgeries, and revealed previously unrecognized lesions that were invisible through the operating microscope. These lesions, such as residual and potentially damaging retinal deformation during pathologic membrane peeling, were visualized in real-time by the surgeon. Our integrated system provides an enhanced 4D surgical visualization platform that can improve current ophthalmic surgical practice and may help develop and refine future microsurgical techniques.

  5. Quantitative 3D imaging of yeast by hard X-ray tomography.

    PubMed

    Zheng, Ting; Li, Wenjie; Guan, Yong; Song, Xiangxia; Xiong, Ying; Liu, Gang; Tian, Yangchao

    2012-05-01

    Full-field hard X-ray tomography could be used to obtain three-dimensional (3D) nanoscale structures of biological samples. The image of the fission yeast, Schizosaccharomyces pombe, was clearly visualized based on Zernike phase contrast imaging technique and heavy metal staining method at a spatial resolution better than 50 nm at the energy of 8 keV. The distributions and shapes of the organelles during the cell cycle were clearly visualized and two types of organelle were distinguished. The results for cells during various phases were compared and the ratios of organelle volume to cell volume can be analyzed quantitatively. It showed that the ratios remained constant between growth and division phase and increased strongly in stationary phase, following the shape and size of two types of organelles changes. Our results demonstrated that hard X-ray microscopy was a complementary method for imaging and revealing structural information for biological samples. Copyright © 2011 Wiley Periodicals, Inc.

  6. OnSight: Multi-platform Visualization of the Surface of Mars

    NASA Astrophysics Data System (ADS)

    Abercrombie, S. P.; Menzies, A.; Winter, A.; Clausen, M.; Duran, B.; Jorritsma, M.; Goddard, C.; Lidawer, A.

    2017-12-01

    A key challenge of planetary geology is to develop an understanding of an environment that humans cannot (yet) visit. Instead, scientists rely on visualizations created from images sent back by robotic explorers, such as the Curiosity Mars rover. OnSight is a multi-platform visualization tool that helps scientists and engineers to visualize the surface of Mars. Terrain visualization allows scientists to understand the scale and geometric relationships of the environment around the Curiosity rover, both for scientific understanding and for tactical consideration in safely operating the rover. OnSight includes a web-based 2D/3D visualization tool, as well as an immersive mixed reality visualization. In addition, OnSight offers a novel feature for communication among the science team. Using the multiuser feature of OnSight, scientists can meet virtually on Mars, to discuss geology in a shared spatial context. Combining web-based visualization with immersive visualization allows OnSight to leverage strengths of both platforms. This project demonstrates how 3D visualization can be adapted to either an immersive environment or a computer screen, and will discuss advantages and disadvantages of both platforms.

  7. Location perception: the X-Files parable.

    PubMed

    Prinzmetal, William

    2005-01-01

    Three aspects of visual object location were investigated: (1) how the visual system integrates information for locating objects, (2) how attention operates to affect location perception, and (3) how the visual system deals with locating an object when multiple objects are present. The theories were described in terms of a parable (the X-Files parable). Then, computer simulations were developed. Finally, predictions derived from the simulations were tested. In the scenario described in the parable, we ask how a system of detectors might locate an alien spaceship, how attention might be implemented in such a spaceship detection system, and how the presence of one spaceship might influence the location perception of another alien spaceship. Experiment 1 demonstrated that location information is integrated with a spatial average rule. In Experiment 2, this rule was applied to a more-samples theory of attention. Experiment 3 demonstrated how the integration rule could account for various visual illusions.

  8. 3D optical coherence tomography image registration for guiding cochlear implant insertion

    NASA Astrophysics Data System (ADS)

    Cheon, Gyeong-Woo; Jeong, Hyun-Woo; Chalasani, Preetham; Chien, Wade W.; Iordachita, Iulian; Taylor, Russell; Niparko, John; Kang, Jin U.

    2014-03-01

    In cochlear implant surgery, an electrode array is inserted into the cochlear canal to restore hearing to a person who is profoundly deaf or significantly hearing impaired. One critical part of the procedure is the insertion of the electrode array, which looks like a thin wire, into the cochlear canal. Although X-ray or computed tomography (CT) could be used as a reference to evaluate the pathway of the whole electrode array, there is no way to depict the intra-cochlear canal and basal turn intra-operatively to help guide insertion of the electrode array. Optical coherent tomography (OCT) is a highly effective way of visualizing internal structures of cochlea. Swept source OCT (SSOCT) having center wavelength of 1.3 micron and 2D Galvonometer mirrors was used to achieve 7-mm depth 3-D imaging. Graphics processing unit (GPU), OpenGL, C++ and C# were integrated for real-time volumetric rendering simultaneously. The 3D volume images taken by the OCT system were assembled and registered which could be used to guide a cochlear implant. We performed a feasibility study using both dry and wet temporal bones and the result is presented.

  9. Study of the structure of 3-D composites based on carbon nanotubes in bovine serum albumin matrix by X-ray microtomography

    NASA Astrophysics Data System (ADS)

    Ignatov, D.; Zhurbina, N.; Gerasimenko, A.

    2017-01-01

    3-D composites are widely used in tissue engineering. A comprehensive analysis by X-ray microtomography was conducted to study the structure of the 3-D composites. Comprehensive analysis of the structure of the 3-D composites consisted of scanning, image reconstruction of shadow projections, two-dimensional and three-dimensional visualization of the reconstructed images and quantitative analysis of the samples. Experimental samples of composites were formed by laser vaporization of the aqueous dispersion BSA and single-walled (SWCNTs) and multi-layer (MWCNTs) carbon nanotubes. The samples have a homogeneous structure over the entire volume, the percentage of porosity of 3-D composites based on SWCNTs and MWCNTs - 16.44%, 28.31%, respectively. An average pore diameter of 3-D composites based on SWCNTs and MWCNTs - 45 μm 93 μm. 3-D composites based on carbon nanotubes in bovine serum albumin matrix can be used in tissue engineering of bone and cartilage, providing cell proliferation and blood vessel sprouting.

  10. The effects of 3D interactive animated graphics on student learning and attitudes in computer-based instruction

    NASA Astrophysics Data System (ADS)

    Moon, Hye Sun

    Visuals are most extensively used as instructional tools in education to present spatially-based information. Recent computer technology allows the generation of 3D animated visuals to extend the presentation in computer-based instruction. Animated visuals in 3D representation not only possess motivational value that promotes positive attitudes toward instruction but also facilitate learning when the subject matter requires dynamic motion and 3D visual cue. In this study, three questions are explored: (1) how 3D graphics affects student learning and attitude, in comparison with 2D graphics; (2) how animated graphics affects student learning and attitude, in comparison with static graphics; and (3) whether the use of 3D graphics, when they are supported by interactive animation, is the most effective visual cues to improve learning and to develop positive attitudes. A total of 145 eighth-grade students participated in a 2 x 2 factorial design study. The subjects were randomly assigned to one of four computer-based instructions: 2D static; 2D animated; 3D static; and 3D animated. The results indicated that: (1) Students in the 3D graphic condition exhibited more positive attitudes toward instruction than those in the 2D graphic condition. No group differences were found between the posttest score of 3D graphic condition and that of 2D graphic condition. However, students in the 3D graphic condition took less time for information retrieval on posttest than those in the 2D graphic condition. (2) Students in the animated graphic condition exhibited slightly more positive attitudes toward instruction than those in the static graphic condition. No group differences were found between the posttest score of animated graphic condition and that of static graphic condition. However, students in the animated graphic condition took less time for information retrieval on posttest than those in the static graphic condition. (3) Students in the 3D animated graphic condition exhibited more positive attitudes toward instruction than those in other treatment conditions (2D static, 2D animated, and 3D static conditions). No group differences were found in the posttest scores among four treatment conditions. However, students in the 3D animated condition took less time for information retrieval on posttest than those in other treatment conditions.

  11. High brightness x ray source for directed energy and holographic imaging applications, phase 2

    NASA Astrophysics Data System (ADS)

    McPherson, Armon; Rhodes, Charles K.

    1992-03-01

    Advances in x-ray imaging technology and x-ray sources are such that a new technology can be brought to commercialization enabling the three-dimensional (3-D) microvisualization of hydrated biological specimens. The Company is engaged in a program whose main goal is the development of a new technology for direct three dimensional (3-D) x-ray holographic imaging. It is believed that this technology will have a wide range of important applications in the defense, medical, and scientific sectors. For example, in the medical area, it is expected that biomedical science will constitute a very active and substantial market, because the application of physical technologies for the direct visualization of biological entities has had a long and extremely fruitful history.

  12. 3D printing meets computational astrophysics: deciphering the structure of η Carinae's inner colliding winds

    NASA Astrophysics Data System (ADS)

    Madura, T. I.; Clementel, N.; Gull, T. R.; Kruip, C. J. H.; Paardekooper, J.-P.

    2015-06-01

    We present the first 3D prints of output from a supercomputer simulation of a complex astrophysical system, the colliding stellar winds in the massive (≳120 M⊙), highly eccentric (e ˜ 0.9) binary star system η Carinae. We demonstrate the methodology used to incorporate 3D interactive figures into a PDF (Portable Document Format) journal publication and the benefits of using 3D visualization and 3D printing as tools to analyse data from multidimensional numerical simulations. Using a consumer-grade 3D printer (MakerBot Replicator 2X), we successfully printed 3D smoothed particle hydrodynamics simulations of η Carinae's inner (r ˜ 110 au) wind-wind collision interface at multiple orbital phases. The 3D prints and visualizations reveal important, previously unknown `finger-like' structures at orbital phases shortly after periastron (φ ˜ 1.045) that protrude radially outwards from the spiral wind-wind collision region. We speculate that these fingers are related to instabilities (e.g. thin-shell, Rayleigh-Taylor) that arise at the interface between the radiatively cooled layer of dense post-shock primary-star wind and the fast (3000 km s-1), adiabatic post-shock companion-star wind. The success of our work and easy identification of previously unrecognized physical features highlight the important role 3D printing and interactive graphics can play in the visualization and understanding of complex 3D time-dependent numerical simulations of astrophysical phenomena.

  13. High-contrast differentiation resolution 3D imaging of rodent brain by X-ray computed microtomography

    NASA Astrophysics Data System (ADS)

    Zikmund, T.; Novotná, M.; Kavková, M.; Tesařová, M.; Kaucká, M.; Szarowská, B.; Adameyko, I.; Hrubá, E.; Buchtová, M.; Dražanová, E.; Starčuk, Z.; Kaiser, J.

    2018-02-01

    The biomedically focused brain research is largely performed on laboratory mice considering a high homology between the human and mouse genomes. A brain has an intricate and highly complex geometrical structure that is hard to display and analyse using only 2D methods. Applying some fast and efficient methods of brain visualization in 3D will be crucial for the neurobiology in the future. A post-mortem analysis of experimental animals' brains usually involves techniques such as magnetic resonance and computed tomography. These techniques are employed to visualize abnormalities in the brains' morphology or reparation processes. The X-ray computed microtomography (micro CT) plays an important role in the 3D imaging of internal structures of a large variety of soft and hard tissues. This non-destructive technique is applied in biological studies because the lab-based CT devices enable to obtain a several-micrometer resolution. However, this technique is always used along with some visualization methods, which are based on the tissue staining and thus differentiate soft tissues in biological samples. Here, a modified chemical contrasting protocol of tissues for a micro CT usage is introduced as the best tool for ex vivo 3D imaging of a post-mortem mouse brain. This way, the micro CT provides a high spatial resolution of the brain microscopic anatomy together with a high tissue differentiation contrast enabling to identify more anatomical details in the brain. As the micro CT allows a consequent reconstruction of the brain structures into a coherent 3D model, some small morphological changes can be given into context of their mutual spatial relationships.

  14. 3D movies for teaching seafloor bathymetry, plate tectonics, and ocean circulation in large undergraduate classes

    NASA Astrophysics Data System (ADS)

    Peterson, C. D.; Lisiecki, L. E.; Gebbie, G.; Hamann, B.; Kellogg, L. H.; Kreylos, O.; Kronenberger, M.; Spero, H. J.; Streletz, G. J.; Weber, C.

    2015-12-01

    Geologic problems and datasets are often 3D or 4D in nature, yet projected onto a 2D surface such as a piece of paper or a projection screen. Reducing the dimensionality of data forces the reader to "fill in" that collapsed dimension in their minds, creating a cognitive challenge for the reader, especially new learners. Scientists and students can visualize and manipulate 3D datasets using the virtual reality software developed for the immersive, real-time interactive 3D environment at the KeckCAVES at UC Davis. The 3DVisualizer software (Billen et al., 2008) can also operate on a desktop machine to produce interactive 3D maps of earthquake epicenter locations and 3D bathymetric maps of the seafloor. With 3D projections of seafloor bathymetry and ocean circulation proxy datasets in a virtual reality environment, we can create visualizations of carbon isotope (δ13C) records for academic research and to aid in demonstrating thermohaline circulation in the classroom. Additionally, 3D visualization of seafloor bathymetry allows students to see features of seafloor most people cannot observe first-hand. To enhance lessons on mid-ocean ridges and ocean basin genesis, we have created movies of seafloor bathymetry for a large-enrollment undergraduate-level class, Introduction to Oceanography. In the past four quarters, students have enjoyed watching 3D movies, and in the fall quarter (2015), we will assess how well 3D movies enhance learning. The class will be split into two groups, one who learns about the Mid-Atlantic Ridge from diagrams and lecture, and the other who learns with a supplemental 3D visualization. Both groups will be asked "what does the seafloor look like?" before and after the Mid-Atlantic Ridge lesson. Then the whole class will watch the 3D movie and respond to an additional question, "did the 3D visualization enhance your understanding of the Mid-Atlantic Ridge?" with the opportunity to further elaborate on the effectiveness of the visualization.

  15. Establishment and Discontinuance Criteria for Runway Visual Range (RVR) at Category I Precision Landing System Runway

    DTIC Science & Technology

    1987-01-01

    ATITN - x.xx 10,000 73,000 General GAAP - x.xx Aviation: 8,900 Military: MILAP - + x.xx 1,900 Subtotal x.xx x RVR System Design Factor x x.xx Subtotal...first three years of operation, ACAP, ATAP, GAAP and MILAP are the numbers of annual instrument approaches by user class, ACITN and ATITN are the...1, falls beneath 0.40. 3. Scope: The above (Phase I) criteria are based primarily on volume of air traffic and frequency and incidence of IFR weather

  16. Animation Strategies for Smooth Transformations Between Discrete Lods of 3d Building Models

    NASA Astrophysics Data System (ADS)

    Kada, Martin; Wichmann, Andreas; Filippovska, Yevgeniya; Hermes, Tobias

    2016-06-01

    The cartographic 3D visualization of urban areas has experienced tremendous progress over the last years. An increasing number of applications operate interactively in real-time and thus require advanced techniques to improve the quality and time response of dynamic scenes. The main focus of this article concentrates on the discussion of strategies for smooth transformation between two discrete levels of detail (LOD) of 3D building models that are represented as restricted triangle meshes. Because the operation order determines the geometrical and topological properties of the transformation process as well as its visual perception by a human viewer, three different strategies are proposed and subsequently analyzed. The simplest one orders transformation operations by the length of the edges to be collapsed, while the other two strategies introduce a general transformation direction in the form of a moving plane. This plane either pushes the nodes that need to be removed, e.g. during the transformation of a detailed LOD model to a coarser one, towards the main building body, or triggers the edge collapse operations used as transformation paths for the cartographic generalization.

  17. Methodological considerations for the 3D measurement of the X-factor and lower trunk movement in golf.

    PubMed

    Joyce, Christopher; Burnett, Angus; Ball, Kevin

    2010-09-01

    It is believed that increasing the X-factor (movement of the shoulders relative to the hips) during the golf swing can increase ball velocity at impact. Increasing the X-factor may also increase the risk of low back pain. The aim of this study was to provide recommendations for the three-dimensional (3D) measurement of the X-factor and lower trunk movement during the golf swing. This three-part validation study involved; (1) developing and validating models and related algorithms (2) comparing 3D data obtained during static positions representative of the golf swing to visual estimates and (3) comparing 3D data obtained during dynamic golf swings to images gained from high-speed video. Of particular interest were issues related to sequence dependency. After models and algorithms were validated, results from parts two and three of the study supported the conclusion that a lateral bending/flexion-extension/axial rotation (ZYX) order of rotation was deemed to be the most suitable Cardanic sequence to use in the assessment of the X-factor and lower trunk movement in the golf swing. The findings of this study have relevance for further research examining the X-factor its relationship to club head speed and lower trunk movement and low back pain in golf.

  18. Technical aspects of virtual liver resection planning.

    PubMed

    Glombitza, G; Lamadé, W; Demiris, A M; Göpfert, M R; Mayer, A; Bahner, M L; Meinzer, H P; Richter, G; Lehnert, T; Herfarth, C

    1998-01-01

    Operability of a liver tumor is depending on its three dimensional relation to the intrahepatic vascular trees which define autonomously functioning liver (sub-)segments. Precise operation planning is complicated by anatomic variability, distortion of the vascular trees by the tumor or preceding liver resections. Because of the missing possibility to track the deformation of the liver during the operation an integration of the resection planning system into an intra-operative navigation system is not feasible. So the main task of an operation planning system in this domain is a quantifiable patient selection by exact prediction of post-operative liver function and a quantifiable resection proposal. The system quantifies the organ structures and resection volumes by means of absolute and relative values. It defines resection planes depending on security margins and the vascular trees and presents the data in visualized form as a 3D movie. The new 3D operation planning system offers quantifiable liver resection proposals based on individualized liver anatomy. The results are visualized in digital movies as well as in quantitative reports.

  19. [Principles of the EOS™ X-ray machine and its use in daily orthopedic practice].

    PubMed

    Illés, Tamás; Somoskeöy, Szabolcs

    2012-02-26

    The EOS™ X-ray machine, based on a Nobel prize-winning invention in Physics in the field of particle detection, is capable of simultaneously capturing biplanar X-ray images by slot scanning of the whole body in an upright, physiological load-bearing position, using ultra low radiation doses. The simultaneous capture of spatially calibrated anterioposterior and lateral images allows the performance of a three-dimensional (3D) surface reconstruction of the skeletal system by a special software. Parts of the skeletal system in X-ray images and 3D-reconstructed models appear in true 1:1 scale for size and volume, thus spinal and vertebral parameters, lower limb axis lengths and angles, as well as any relevant clinical parameters in orthopedic practice could be very precisely measured and calculated. Visualization of 3D reconstructed models in various views by the sterEOS 3D software enables the presentation of top view images, through which one can analyze the rotational conditions of lower limbs, joints and spine deformities in horizontal plane and this provides revolutionary novel possibilities in orthopedic surgery, especially in spine surgery.

  20. Automatic transfer function generation for volume rendering of high-resolution x-ray 3D digital mammography images

    NASA Astrophysics Data System (ADS)

    Alyassin, Abdal M.

    2002-05-01

    3D Digital mammography (3DDM) is a new technology that provides high resolution X-ray breast tomographic data. Like any other tomographic medical imaging modalities, viewing a stack of tomographic images may require time especially if the images are of large matrix size. In addition, it may cause difficulty to conceptually construct 3D breast structures. Therefore, there is a need to readily visualize the data in 3D. However, one of the issues that hinder the usage of volume rendering (VR) is finding an automatic way to generate transfer functions that efficiently map the important diagnostic information in the data. We have developed a method that randomly samples the volume. Based on the mean and the standard deviation of these samples, the technique determines the lower limit and upper limit of a piecewise linear ramp transfer function. We have volume rendered several 3DDM data using this technique and compared visually the outcome with the result from a conventional automatic technique. The transfer function generated through the proposed technique provided superior VR images over the conventional technique. Furthermore, the improvement in the reproducibility of the transfer function correlated with the number of samples taken from the volume at the expense of the processing time.

  1. Visualization of Potential Energy Function Using an Isoenergy Approach and 3D Prototyping

    ERIC Educational Resources Information Center

    Teplukhin, Alexander; Babikov, Dmitri

    2015-01-01

    In our three-dimensional world, one can plot, see, and comprehend a function of two variables at most, V(x,y). One cannot plot a function of three or more variables. For this reason, visualization of the potential energy function in its full dimensionality is impossible even for the smallest polyatomic molecules, such as triatomics. This creates…

  2. Survey of Network Visualization Tools

    DTIC Science & Technology

    2007-12-01

    Dimensionality • 2D Comments: Deployment Type: • Components for tool building • Standalone Tool OS: • Windows Extensibility • ActiveX ...Visual Basic Comments: Interoperability Daisy is fully compliant with Microsoft’s ActiveX , therefore, other Windows based programs can...other functions that improve analytic decision making. Available in ActiveX , C++, Java, and .NET editions. • Tom Sawyer Visualization: Enables you to

  3. ANGIOCARE: an automated system for fast three-dimensional coronary reconstruction by integrating angiographic and intracoronary ultrasound data.

    PubMed

    Bourantas, Christos V; Kalatzis, Fanis G; Papafaklis, Michail I; Fotiadis, Dimitrios I; Tweddel, Ann C; Kourtis, Iraklis C; Katsouras, Christos S; Michalis, Lampros K

    2008-08-01

    The development of an automated, user-friendly system (ANGIOCARE), for rapid three-dimensional (3D) coronary reconstruction, integrating angiographic and, intracoronary ultrasound (ICUS) data. Biplane angiographic and ICUS sequence images are imported into the system where a prevalidated method is used for coronary reconstruction. This incorporates extraction of the catheter path from two end-diastolic X-ray images and detection of regions of interest (lumen, outer vessel wall) in the ICUS sequence by an automated border detection algorithm. The detected borders are placed perpendicular to the catheter path and established algorithms used to estimate their absolute orientation. The resulting 3D object is imported into an advanced visualization module with which the operator can interact, examine plaque distribution (depicted as a color coded map) and assess plaque burden by virtual endoscopy. Data from 19 patients (27 vessels) undergoing biplane angiography and ICUS were examined. The reconstructed vessels were 21.3-80.2 mm long. The mean difference was 0.9 +/- 2.9% between the plaque volumes measured using linear 3D ICUS analysis and the volumes, estimated by taking into account the curvature of the vessel. The time required to reconstruct a luminal narrowing of 25 mm was approximately 10 min. The ANGIOCARE system provides rapid coronary reconstruction allowing the operator accurately to estimate the length of the lesion and determine plaque distribution and volume. (c) 2008 Wiley-Liss, Inc.

  4. 3D display considerations for rugged airborne environments

    NASA Astrophysics Data System (ADS)

    Barnidge, Tracy J.; Tchon, Joseph L.

    2015-05-01

    The KC-46 is the next generation, multi-role, aerial refueling tanker aircraft being developed by Boeing for the United States Air Force. Rockwell Collins has developed the Remote Vision System (RVS) that supports aerial refueling operations under a variety of conditions. The system utilizes large-area, high-resolution 3D displays linked with remote sensors to enhance the operator's visual acuity for precise aerial refueling control. This paper reviews the design considerations, trade-offs, and other factors related to the selection and ruggedization of the 3D display technology for this military application.

  5. National Dam Safety Program. Wappingers Falls Dam (I.D. Number N.Y. 3, D.E.C. 613A), Hudson River Basin, Dutchess County, New York. Phase 1 Inspection Report

    DTIC Science & Technology

    1980-09-30

    Classification 2I e. Ownership 2f. Purpose of Dam 2 g. Design and Construction History 2h. Normal Operating Procedure 2 1.3 PERTINENT DATA 2 a. Drainage...4 2.2 SUBSURFACE INVESTIGATION 4 2.3 DAM AND APPURTENANT STRUCTURES 4 2.4 CONSTRUCTION RECORDS 4 2.5 OPERATION RECORDS 2.6 EVALUATION OF DATA 5 4...12 a. Visual Observations 12 b. Design and Construction Data 12 c. Stability Analysis 12 d. Operating Records 13 e. Post- Construction Changes 13 f

  6. Visualization of Hyperconjugation and Subsequent Structural Distortions through 3D Printing of Crystal Structures.

    PubMed

    Mithila, Farha J; Oyola-Reynoso, Stephanie; Thuo, Martin M; Atkinson, Manza Bj

    2016-01-01

    Structural distortions due to hyperconjugation in organic molecules, like norbornenes, are well captured through X-ray crystallographic data, but are sometimes difficult to visualize especially for those applying chemical knowledge and are not chemists. Crystal structure from the Cambridge database were downloaded and converted to .stl format. The structures were then printed at the desired scale using a 3D printer. Replicas of the crystal structures were accurately reproduced in scale and any resulting distortions were clearly visible from the macroscale models. Through space interactions or effect of through space hyperconjugation was illustrated through loss of symmetry or distortions thereof. The norbornene structures exhibits distortion that cannot be observed through conventional ball and stick modelling kits. We show that 3D printed models derived from crystallographic data capture even subtle distortions in molecules. We translate such crystallographic data into scaled-up models through 3D printing.

  7. Visualization of Buffer Capacity with 3-D "Topo" Surfaces: Buffer Ridges, Equivalence Point Canyons and Dilution Ramps

    ERIC Educational Resources Information Center

    Smith, Garon C.; Hossain, Md Mainul

    2016-01-01

    BufCap TOPOS is free software that generates 3-D topographical surfaces ("topos") for acid-base equilibrium studies. It portrays pH and buffer capacity behavior during titration and dilution procedures. Topo surfaces are created by plotting computed pH and buffer capacity values above a composition grid with volume of NaOH as the x axis…

  8. A 176×144 148dB adaptive tone-mapping imager

    NASA Astrophysics Data System (ADS)

    Vargas-Sierra, S.; Liñán-Cembrano, G.; Rodríguez-Vázquez, A.

    2012-03-01

    This paper presents a 176x144 (QCIF) HDR image sensor where visual information is simultaneously captured and adaptively compressed by means of an in-pixel tone mapping scheme. The tone mapping curve (TMC) is calculated from the histogram of a Time Stamp image captured in the previous frame, which serves as a probability indicator of the distribution of illuminations within the present frame. The chip produces 7-bit/pixel images that can map illuminations from 311μlux to 55.3 klux in a single frame in a way that each pixel decides when to stop observing photocurrent integration -with extreme values captured at 8s and 2.34μs respectively. Pixels size is 33x33μm2, which includes a 3x3μm2 Nwell- Psubstrate photodiode and an autozeroing technique for establishing the reset voltage, which cancels most of the offset contributions created by the analog processing circuitry. Dark signal (10.8 mV/s ) effects in the final image are attenuated by an automatic programming of the DAC top voltage. Measured characteristics are Sensitivity 5.79 V/lux.s , FWC 12.2ke-, Conversion Factor 129(e-/DN), and Read Noise 25e-. The chip has been designed in the 0.35μm OPTO technology from Austriamicrosystems (AMS). Due to the focal plane operation, this architecture is especially well suited to be implemented in a 3D (vertical stacking) technology using per-pixel TSVs.

  9. [Computerized monitoring system in the operating center with UNIX and X-window].

    PubMed

    Tanaka, Y; Hashimoto, S; Chihara, E; Kinoshita, T; Hirose, M; Nakagawa, M; Murakami, T

    1992-01-01

    We previously reported the fully automated data logging system in the operating center. Presently, we revised the system using a highly integrated operating system, UNIX instead of OS/9. With this multi-task and multi-window (X-window) system, we could monitor all 12 rooms in the operating center at a time. The system in the operating center consists of 2 computers, SONY NEWS1450 (UNIX workstation) and Sord M223 (CP/M, data logger). On the bitmapped display of the workstation, using X-window, the data of all the operating rooms can be visualized. Furthermore, 2 other minicomputers (Fujitsu A50 in the conference room, and A60 in the ICU) and a workstation (Sun3-80 in the ICU) were connected with ethernet. With the remote login function (NFS), we could easily obtain the data during the operation from outside the operating center. This system works automatically and needs no routine maintenance.

  10. Preoperative simulation for the planning of microsurgical clipping of intracranial aneurysms.

    PubMed

    Marinho, Paulo; Vermandel, Maximilien; Bourgeois, Philippe; Lejeune, Jean-Paul; Mordon, Serge; Thines, Laurent

    2014-12-01

    The safety and success of intracranial aneurysm (IA) surgery could be improved through the dedicated application of simulation covering the procedure from the 3-dimensional (3D) description of the surgical scene to the visual representation of the clip application. We aimed in this study to validate the technical feasibility and clinical relevance of such a protocol. All patients preoperatively underwent 3D magnetic resonance imaging and 3D computed tomography angiography to build 3D reconstructions of the brain, cerebral arteries, and surrounding cranial bone. These 3D models were segmented and merged using Osirix, a DICOM image processing application. This provided the surgical scene that was subsequently imported into Blender, a modeling platform for 3D animation. Digitized clips and appliers could then be manipulated in the virtual operative environment, allowing the visual simulation of clipping. This simulation protocol was assessed in a series of 10 IAs by 2 neurosurgeons. The protocol was feasible in all patients. The visual similarity between the surgical scene and the operative view was excellent in 100% of the cases, and the identification of the vascular structures was accurate in 90% of the cases. The neurosurgeons found the simulation helpful for planning the surgical approach (ie, the bone flap, cisternal opening, and arterial tree exposure) in 100% of the cases. The correct number of final clip(s) needed was predicted from the simulation in 90% of the cases. The preoperatively expected characteristics of the optimal clip(s) (ie, their number, shape, size, and orientation) were validated during surgery in 80% of the cases. This study confirmed that visual simulation of IA clipping based on the processing of high-resolution 3D imaging can be effective. This is a new and important step toward the development of a more sophisticated integrated simulation platform dedicated to cerebrovascular surgery.

  11. On conditions for invertibility of difference and differential operators in weight spaces

    NASA Astrophysics Data System (ADS)

    Bichegkuev, Mairbek S.

    2011-08-01

    We obtain necessary and sufficient conditions for the invertibility of the difference operator D_E\\colon D(D_E)\\subset l^p_\\alpha \\to l^p_\\alpha, (D_E x)(n)=x(n+1)-Bx(n), n\\in {Z}_+, whose domain D(D_E) is given by the condition x(0)\\in E, where l^p_\\alpha=l^p_\\alpha({Z}_+,X), p\\in \\lbrack 1,\\infty \\rbrack , is the Banach space of sequences (of vectors in a Banach space X) summable with weight \\alpha\\colon{Z}_+\\to (0,\\infty) for p\\in \\lbrack 1,\\infty) and bounded with respect to \\alpha for p=\\infty, B\\colon X\\to X is a bounded linear operator, and E is a closed B-invariant subspace of X. We give applications to the invertibility of differential operators with an unbounded operator coefficient (the generator of a strongly continuous operator semigroup) in weight spaces of functions.

  12. MSX-3D: a tool to validate 3D protein models using mass spectrometry.

    PubMed

    Heymann, Michaël; Paramelle, David; Subra, Gilles; Forest, Eric; Martinez, Jean; Geourjon, Christophe; Deléage, Gilbert

    2008-12-01

    The technique of chemical cross-linking followed by mass spectrometry has proven to bring valuable information about the protein structure and interactions between proteic subunits. It is an effective and efficient way to experimentally investigate some aspects of a protein structure when NMR and X-ray crystallography data are lacking. We introduce MSX-3D, a tool specifically geared to validate protein models using mass spectrometry. In addition to classical peptides identifications, it allows an interactive 3D visualization of the distance constraints derived from a cross-linking experiment. Freely available at http://proteomics-pbil.ibcp.fr

  13. The OpenEarth Framework (OEF) for the 3D Visualization of Integrated Earth Science Data

    NASA Astrophysics Data System (ADS)

    Nadeau, David; Moreland, John; Baru, Chaitan; Crosby, Chris

    2010-05-01

    Data integration is increasingly important as we strive to combine data from disparate sources and assemble better models of the complex processes operating at the Earth's surface and within its interior. These data are often large, multi-dimensional, and subject to differing conventions for data structures, file formats, coordinate spaces, and units of measure. When visualized, these data require differing, and sometimes conflicting, conventions for visual representations, dimensionality, symbology, and interaction. All of this makes the visualization of integrated Earth science data particularly difficult. The OpenEarth Framework (OEF) is an open-source data integration and visualization suite of applications and libraries being developed by the GEON project at the University of California, San Diego, USA. Funded by the NSF, the project is leveraging virtual globe technology from NASA's WorldWind to create interactive 3D visualization tools that combine and layer data from a wide variety of sources to create a holistic view of features at, above, and beneath the Earth's surface. The OEF architecture is open, cross-platform, modular, and based upon Java. The OEF's modular approach to software architecture yields an array of mix-and-match software components for assembling custom applications. Available modules support file format handling, web service communications, data management, user interaction, and 3D visualization. File parsers handle a variety of formal and de facto standard file formats used in the field. Each one imports data into a general-purpose common data model supporting multidimensional regular and irregular grids, topography, feature geometry, and more. Data within these data models may be manipulated, combined, reprojected, and visualized. The OEF's visualization features support a variety of conventional and new visualization techniques for looking at topography, tomography, point clouds, imagery, maps, and feature geometry. 3D data such as seismic tomography may be sliced by multiple oriented cutting planes and isosurfaced to create 3D skins that trace feature boundaries within the data. Topography may be overlaid with satellite imagery, maps, and data such as gravity and magnetics measurements. Multiple data sets may be visualized simultaneously using overlapping layers within a common 3D coordinate space. Data management within the OEF handles and hides the inevitable quirks of differing file formats, web protocols, storage structures, coordinate spaces, and metadata representations. Heuristics are used to extract necessary metadata used to guide data and visual operations. Derived data representations are computed to better support fluid interaction and visualization while the original data is left unchanged in its original form. Data is cached for better memory and network efficiency, and all visualization makes use of 3D graphics hardware support found on today's computers. The OpenEarth Framework project is currently prototyping the software for use in the visualization, and integration of continental scale geophysical data being produced by EarthScope-related research in the Western US. The OEF is providing researchers with new ways to display and interrogate their data and is anticipated to be a valuable tool for future EarthScope-related research.

  14. Multiscale microstructural characterization of Sn-rich alloys by three dimensional (3D) X-ray synchrotron tomography and focused ion beam (FIB) tomography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yazzie, K.E.; Williams, J.J.; Phillips, N.C.

    2012-08-15

    Sn-rich (Pb-free) alloys serve as electrical and mechanical interconnects in electronic packaging. It is critical to quantify the microstructures of Sn-rich alloys to obtain a fundamental understanding of their properties. In this work, the intermetallic precipitates in Sn-3.5Ag and Sn-0.7Cu, and globular lamellae in Sn-37Pb solder joints were visualized and quantified using 3D X-ray synchrotron tomography and focused ion beam (FIB) tomography. 3D reconstructions were analyzed to extract statistics on particle size and spatial distribution. In the Sn-Pb alloy the interconnectivity of Sn-rich and Pb-rich constituents was quantified. It will be shown that multiscale characterization using 3D X-ray and FIBmore » tomography enabled the characterization of the complex morphology, distribution, and statistics of precipitates and contiguous phases over a range of length scales. - Highlights: Black-Right-Pointing-Pointer Multiscale characterization by X-ray synchrotron and focused ion beam tomography. Black-Right-Pointing-Pointer Characterized microstructural features in several Sn-based alloys. Black-Right-Pointing-Pointer Quantified size, fraction, and clustering of microstructural features.« less

  15. Application of 3-Dimensional Printing in a Case of Osteogenesis Imperfecta for Patient Education, Anatomic Understanding, Preoperative Planning, and Intraoperative Evaluation.

    PubMed

    Eisenmenger, Laura B; Wiggins, Richard H; Fults, Daniel W; Huo, Eugene J

    2017-11-01

    The techniques and applications of 3-dimensional (3D) printing have progressed at a fast pace. In the last 10 years, there has been significant progress in applying this technology to medical applications. We present a case of osteogenesis imperfecta in which treatment was aided by prospectively using patient-specific, anatomically accurate 3D prints of the calvaria. The patient-specific, anatomically accurate 3D prints were used in the clinic and in the operating room to augment patient education, improve surgical decision making, and enhance preoperative planning. A 41-year-old woman with osteogenesis imperfecta and an extensive neurosurgical history presented for cranioplasty revision. Computed tomography (CT) data obtained as part of routine preoperative imaging were processed into a 3D model. The 3D patient-specific models were used in the clinic for patient education and in the operating room for preoperative visualization, planning, and intraoperative evaluation of anatomy. The patient reported the 3D models improved her understanding and comfort with the planned surgery when compared with discussing the procedure with the neurosurgeon or viewing the CT images with a neuroradiologist. The neurosurgeon reported an improved understanding of the patient's anatomy and potential cause of patient symptoms as well as improved preoperative planning compared with viewing the CT imaging alone. The neurosurgeon also reported an improvement in the planned surgical approach with a better intraoperative visualization and confirmation of the regions of planned calvarial resection. The use of patient-specific, anatomically accurate 3D prints may improve patient education, surgeon understanding and visualization, preoperative decision making, and intraoperative management. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Operator vision aids for space teleoperation assembly and servicing

    NASA Technical Reports Server (NTRS)

    Brooks, Thurston L.; Ince, Ilhan; Lee, Greg

    1992-01-01

    This paper investigates concepts for visual operator aids required for effective telerobotic control. Operator visual aids, as defined here, mean any operational enhancement that improves man-machine control through the visual system. These concepts were derived as part of a study of vision issues for space teleoperation. Extensive literature on teleoperation, robotics, and human factors was surveyed to definitively specify appropriate requirements. This paper presents these visual aids in three general categories of camera/lighting functions, display enhancements, and operator cues. In the area of camera/lighting functions concepts are discussed for: (1) automatic end effector or task tracking; (2) novel camera designs; (3) computer-generated virtual camera views; (4) computer assisted camera/lighting placement; and (5) voice control. In the technology area of display aids, concepts are presented for: (1) zone displays, such as imminent collision or indexing limits; (2) predictive displays for temporal and spatial location; (3) stimulus-response reconciliation displays; (4) graphical display of depth cues such as 2-D symbolic depth, virtual views, and perspective depth; and (5) view enhancements through image processing and symbolic representations. Finally, operator visual cues (e.g., targets) that help identify size, distance, shape, orientation and location are discussed.

  17. Debris Dispersion Model Using Java 3D

    NASA Technical Reports Server (NTRS)

    Thirumalainambi, Rajkumar; Bardina, Jorge

    2004-01-01

    This paper describes web based simulation of Shuttle launch operations and debris dispersion. Java 3D graphics provides geometric and visual content with suitable mathematical model and behaviors of Shuttle launch. Because the model is so heterogeneous and interrelated with various factors, 3D graphics combined with physical models provides mechanisms to understand the complexity of launch and range operations. The main focus in the modeling and simulation covers orbital dynamics and range safety. Range safety areas include destruct limit lines, telemetry and tracking and population risk near range. If there is an explosion of Shuttle during launch, debris dispersion is explained. The shuttle launch and range operations in this paper are discussed based on the operations from Kennedy Space Center, Florida, USA.

  18. Update on Rover Sequencing and Visualization Program

    NASA Technical Reports Server (NTRS)

    Cooper, Brian; Hartman, Frank; Maxwell, Scott; Yen, Jeng; Wright, John; Balacuit, Carlos

    2005-01-01

    The Rover Sequencing and Visualization Program (RSVP) has been updated. RSVP was reported in Rover Sequencing and Visualization Program (NPO-30845), NASA Tech Briefs, Vol. 29, No. 4 (April 2005), page 38. To recapitulate: The Rover Sequencing and Visualization Program (RSVP) is the software tool to be used in the Mars Exploration Rover (MER) mission for planning rover operations and generating command sequences for accomplishing those operations. RSVP combines three-dimensional (3D) visualization for immersive exploration of the operations area, stereoscopic image display for high-resolution examination of the downlinked imagery, and a sophisticated command-sequence editing tool for analysis and completion of the sequences. RSVP is linked with actual flight code modules for operations rehearsal to provide feedback on the expected behavior of the rover prior to committing to a particular sequence. Playback tools allow for review of both rehearsed rover behavior and downlinked results of actual rover operations. These can be displayed simultaneously for comparison of rehearsed and actual activities for verification. The primary inputs to RSVP are downlink data products from the Operations Storage Server (OSS) and activity plans generated by the science team. The activity plans are high-level goals for the next day s activities. The downlink data products include imagery, terrain models, and telemetered engineering data on rover activities and state. The Rover Sequence Editor (RoSE) component of RSVP performs activity expansion to command sequences, command creation and editing with setting of command parameters, and viewing and management of rover resources. The HyperDrive component of RSVP performs 2D and 3D visualization of the rover s environment, graphical and animated review of rover predicted and telemetered state, and creation and editing of command sequences related to mobility and Instrument Deployment Device (robotic arm) operations. Additionally, RoSE and HyperDrive together evaluate command sequences for potential violations of flight and safety rules. The products of RSVP include command sequences for uplink that are stored in the Distributed Object Manager (DOM) and predicted rover state histories stored in the OSS for comparison and validation of downlinked telemetry. The majority of components comprising RSVP utilize the MER command and activity dictionaries to automatically customize the system for MER activities.

  19. Implantation of a customized toric intraocular lens for correction of post-keratoplasty astigmatism

    PubMed Central

    Srinivasan, S; Ting, D S J; Lyall, D A M

    2013-01-01

    Purpose To report visual and refractive outcomes, and endothelial cell loss following primary and secondary ‘piggyback' toric intraocular lens (IOL) implantation in patients with high post-penetrating keratoplasty (PK) astigmatism. Methods Prospective case series. Nine eyes of nine patients with post-PK astigmatism were consecutively recruited for implantation of a customized toric IOL. Six underwent simultaneous phacoemulsification (PE) and three pseudophakic eyes had a secondary ‘piggyback' toric IOL implanted in the ciliary sulcus. Mean follow-up time was 17.2±7.7 months. Pre- and post-operative uncorrected (UDVA) and best-corrected (BDVA) distance visual acuities and refractive errors were collected for comparison. Cartesian astigmatic vectors were calculated to identify a change in the magnitude of astigmatism pre- compared to postoperatively. Pre- and post-operative endothelial cell counts were also collected for analysis. Results UDVA (logMAR) improved from 1.13±0.51 preoperatively to 0.48±0.24 postoperatively (P-value=0.003). There was no significant change in BDVA (P-value=0.905) from 0.31±0.27 to 0.26±0.19. Corneal astigmatism preoperatively was 6.57±4.40 diopters (D). Post-operative refractive cylinder was 0.83±1.09 D compared to 3.89±4.01 D preoperatively (P=0.039). Analysis of astigmatic Cartesian x and y coordinates found a significant reduction postoperatively compared to preoperatively (P=0.005 and P=0.002), respectively. Mean endothelial cell loss was 9.9%. Conclusion: Implantation of a customized primary or secondary ‘piggyback' toric IOL serves as an effective modality in treating patients with high post-PK astigmatism. PMID:23348728

  20. Comparison of visual acuity of the patients on the first day after sub-Bowman keratomileusis or laser in situ keratomileusis

    PubMed Central

    Zhao, Wei; Wu, Ting; Dong, Ze-Hong; Feng, Jie; Ren, Yu-Feng; Wang, Yu-Sheng

    2016-01-01

    AIM To compare recovery of the visual acuity in patients one day after sub-Bowman keratomileusis (SBK) or laser in situ keratomileusis (LASIK). METHODS Data from 5923 eyes in 2968 patients that received LASIK (2755 eyes) or SBK (3168 eyes) were retrospectively analyzed. The eyes were divided into 4 groups according to preoperative spherical equivalent: between -12.00 to -9.00 D, extremely high myopia (n=396, including 192 and 204 in SBK and LASIK groups, respectively); -9.00 to -6.00 D, high myopia (n=1822, including 991 and 831 in SBK and LASIK groups, respectively), -6.00 to -3.00 D, moderate myopia (n=3071, including 1658 and 1413 in SBK and LASIK groups, respectively), and -3.00 to 0.00 D, low myopia (n=634, including 327 and 307 in SBK and LASIK groups, respectively). Uncorrected logMAR visual acuity values of patients were assessed under standard natural light. Analysis of variance was used for comparisons among different groups. RESULTS Uncorrected visual acuity values were 0.0115±0.1051 and 0.0466±0.1477 at day 1 after operation for patients receiving SBK and LASIK, respectively (P<0.01); visual acuity values of 0.1854±0.1842, 0.0615±0.1326, -0.0033±0.0978, and -0.0164±0.0972 were obtained for patients in the extremely high, high, moderate, and low myopia groups, respectively (P<0.01). In addition, significant differences in visual acuity at day 1 after operation were found between patients receiving SBK and LASIK in each myopia subgroup. CONCLUSION Compared with LASIK, SBK is safer and more effective, with faster recovery. Therefore, SBK is more likely to be accepted by patients than LASIK for better uncorrected visual acuity the day following operation. PMID:27158619

  1. Touch Interaction with 3D Geographical Visualization on Web: Selected Technological and User Issues

    NASA Astrophysics Data System (ADS)

    Herman, L.; Stachoň, Z.; Stuchlík, R.; Hladík, J.; Kubíček, P.

    2016-10-01

    The use of both 3D visualization and devices with touch displays is increasing. In this paper, we focused on the Web technologies for 3D visualization of spatial data and its interaction via touch screen gestures. At the first stage, we compared the support of touch interaction in selected JavaScript libraries on different hardware (desktop PCs with touch screens, tablets, and smartphones) and software platforms. Afterward, we realized simple empiric test (within-subject design, 6 participants, 2 simple tasks, LCD touch monitor Acer and digital terrain models as stimuli) focusing on the ability of users to solve simple spatial tasks via touch screens. An in-house testing web tool was developed and used based on JavaScript, PHP, and X3DOM languages and Hammer.js libraries. The correctness of answers, speed of users' performances, used gestures, and a simple gesture metric was recorded and analysed. Preliminary results revealed that the pan gesture is most frequently used by test participants and it is also supported by the majority of 3D libraries. Possible gesture metrics and future developments including the interpersonal differences are discussed in the conclusion.

  2. 3D investigation of inclusions in diamonds using X-ray micro-tomography

    NASA Astrophysics Data System (ADS)

    Parisatto, M.; Nestola, F.; Artioli, G.; Nimis, P.; Harris, J. W.; Kopylova, M.; Pearson, G. D.

    2012-04-01

    The study of mineral inclusions in diamonds is providing invaluable insights into the geochemistry, geodynamics and geophysics of the Earth's mantle. Over the last two decades, the identification of different inclusion assemblages allowed to recognize diamonds deriving from the deep upper mantle, the transition zone and even the lower mantle. In such research field the in-situ investigation of inclusions using non-destructive techniques is often essential but still remains a challenging task. In particular, conventional 2D imaging techniques (e.g. SEM) are limited to the investigation of surfaces and the lack of access to the third dimension represents a major limitation when trying to extract quantitative information. Another critical aspect is related to sample preparation (cutting, polishing) which is typically very invasive. Nowadays, X-ray computed micro-tomography (X-μCT) allows to overcome such limitations, enabling the internal microstructure of totally undisturbed samples to be visualized in a three-dimensional (3D) manner at the sub-micrometric scale. The final output of a micro-tomography experiment is a greyvalue 3D map of the variations of the X-ray attenuation coefficient (µ) within the studied object. The high X-ray absorption contrast between diamond (almost transparent to X-rays) and the typical inclusion-forming minerals (olivines, garnets, pyroxenes, oxides and sulphides) makes X-μCT a straightforward method for the 3D visualization of inclusions and for the study of their spatial relationships with the diamond host. In this work we applied microfocus X-μCT to investigate silicate inclusions still trapped in diamonds, in order to obtain in-situ information on their exact position, crystal size, shape and X-ray absorption coefficient (which is related to their composition). We selected diamond samples from different deposits containing mainly olivine and garnet inclusions. The investigated samples derived from the Udachnaya pipe (Siberia, Russia), the Jericho Kimberlite (Slave Craton, Canada) and São Luiz-Juina (Brazil). The information obtained by tomographic experiments were combined with X-ray single-crystal diffraction data (see Nestola et al 2011) in order to identify the inclusion parageneses (peridotitic, eclogitic or websteritic) and to finally determine the origin of the studied diamonds. Our results showed that, by combining X-μCT with X-ray diffraction data, it is possible to exactly determine the 3D position of each inclusion together with their crystal size, even though they cannot be detected by using an optical microscope. In addition, such method could have strong crystallographic implications for inclusions still trapped in diamonds as it enables the application of a reliable numerical absorption correction to the 3D intensity data collections. REF. Nestola, F., Nimis, P., Ziberna, L., Longo, M., Marzoli, A., Harris, J.W., Manghnani, M.H., Fedortchouk, Y. (2011): First crystal-structure determination of olivine in diamond: composition and implications for provenance in the Earth's mantle. Earth Planet. Sci. Lett., 305, 249-255.

  3. Dynamic Paper Constructions for Easier Visualization of Molecular Symmetry

    ERIC Educational Resources Information Center

    Sein, Lawrence T., Jr.

    2010-01-01

    A system for construction of simple poster-board models is described. The models dynamically demonstrate the symmetry operations of proper rotation, improper rotation, reflection, and inversion for the chemically important point groups D[subscript 3h], D[subscript 4h], D[subscript 5h], D[subscript 6h], T[subscript d], and O[subscript h]. The…

  4. Non-isothermal two-phase transport in the polymer electrolyte membrane fuel cell microporous layer

    NASA Astrophysics Data System (ADS)

    Ge, Nan

    This thesis investigates the water transport mechanisms in the crack-free microporous layer (MPL) of a polymer electrolyte membrane (PEM) fuel cell. Synchrotron X-ray radiography was used to visualize and quantify the in situ liquid water in the gas diffusion layers (GDLs) of an operating fuel cell. A methodology was developed to correct the artefact of imaging sample movement. Furthermore, to address inaccuracies due to the scattering effect and higher harmonics at the synchrotron beamline, a calibration technique was introduced in order to experimentally determine the liquid water X-ray attenuation coefficient. Through in situ radiography, liquid water breakthrough events were observed in the MPL, and measured water thicknesses were used as inputs into a one-dimensional (1D) heat and mass transport model. The 1D model was used to describe the coupled relationship between liquid and vapour transport through the cathode MPL and the temperature distributions in the operating fuel cell.

  5. [Development of a software for 3D virtual phantom design].

    PubMed

    Zou, Lian; Xie, Zhao; Wu, Qi

    2014-02-01

    In this paper, we present a 3D virtual phantom design software, which was developed based on object-oriented programming methodology and dedicated to medical physics research. This software was named Magical Phan tom (MPhantom), which is composed of 3D visual builder module and virtual CT scanner. The users can conveniently construct any complex 3D phantom, and then export the phantom as DICOM 3.0 CT images. MPhantom is a user-friendly and powerful software for 3D phantom configuration, and has passed the real scene's application test. MPhantom will accelerate the Monte Carlo simulation for dose calculation in radiation therapy and X ray imaging reconstruction algorithm research.

  6. One-Loop One-Point Functions in Gauge-Gravity Dualities with Defects.

    PubMed

    Buhl-Mortensen, Isak; de Leeuw, Marius; Ipsen, Asger C; Kristjansen, Charlotte; Wilhelm, Matthias

    2016-12-02

    We initiate the calculation of loop corrections to correlation functions in 4D defect conformal field theories (dCFTs). More precisely, we consider N=4 SYM theory with a codimension-one defect separating two regions of space, x_{3}>0 and x_{3}<0, where the gauge group is SU(N) and SU(N-k), respectively. This setup is made possible by some of the real scalar fields acquiring a nonvanishing and x_{3}-dependent vacuum expectation value for x_{3}>0. The holographic dual is the D3-D5 probe brane system where the D5-brane geometry is AdS_{4}×S^{2} and a background gauge field has k units of flux through the S^{2}. We diagonalize the mass matrix of the dCFT making use of fuzzy-sphere coordinates and we handle the x_{3} dependence of the mass terms in the 4D Minkowski space propagators by reformulating these as standard massive AdS_{4} propagators. Furthermore, we show that only two Feynman diagrams contribute to the one-loop correction to the one-point function of any single-trace operator and we explicitly calculate this correction in the planar limit for the simplest chiral primary. The result of this calculation is compared to an earlier string-theory computation in a certain double scaling limit and perfect agreement is found. Finally, we discuss how to generalize our calculation to any single-trace operator, to finite N, and to other types of observables such as Wilson loops.

  7. Structured illumination microscopy for dual-modality 3D sub-diffraction resolution fluorescence and refractive-index reconstruction

    PubMed Central

    Chowdhury, Shwetadwip; Eldridge, Will J.; Wax, Adam; Izatt, Joseph A.

    2017-01-01

    Though structured illumination (SI) microscopy is a popular imaging technique conventionally associated with fluorescent super-resolution, recent works have suggested its applicability towards sub-diffraction resolution coherent imaging with quantitative endogenous biological contrast. Here, we demonstrate that SI can efficiently integrate together the principles of fluorescent super-resolution and coherent synthetic aperture to achieve 3D dual-modality sub-diffraction resolution, fluorescence and refractive-index (RI) visualizations of biological samples. We experimentally demonstrate this framework by introducing a SI microscope capable of 3D sub-diffraction resolution fluorescence and RI imaging, and verify its biological visualization capabilities by experimentally reconstructing 3D RI/fluorescence visualizations of fluorescent calibration microspheres as well as alveolar basal epithelial adenocarcinoma (A549) and human colorectal adenocarcinmoa (HT-29) cells, fluorescently stained for F-actin. This demonstration may suggest SI as an especially promising imaging technique to enable future biological studies that explore synergistically operating biophysical/biochemical and molecular mechanisms at sub-diffraction resolutions. PMID:29296504

  8. Characterization of separability and entanglement in (2xD)- and (3xD)-dimensional systems by single-qubit and single-qutrit unitary transformations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Giampaolo, Salvatore M.; CNR-INFM Coherentia, Naples; CNISM Unita di Salerno and INFN Sezione di Napoli, Gruppo collegato di Salerno, Baronissi

    2007-10-15

    We investigate the geometric characterization of pure state bipartite entanglement of (2xD)- and (3xD)-dimensional composite quantum systems. To this aim, we analyze the relationship between states and their images under the action of particular classes of local unitary operations. We find that invariance of states under the action of single-qubit and single-qutrit transformations is a necessary and sufficient condition for separability. We demonstrate that in the (2xD)-dimensional case the von Neumann entropy of entanglement is a monotonic function of the minimum squared Euclidean distance between states and their images over the set of single qubit unitary transformations. Moreover, both inmore » the (2xD)- and in the (3xD)-dimensional cases the minimum squared Euclidean distance exactly coincides with the linear entropy [and thus as well with the tangle measure of entanglement in the (2xD)-dimensional case]. These results provide a geometric characterization of entanglement measures originally established in informational frameworks. Consequences and applications of the formalism to quantum critical phenomena in spin systems are discussed.« less

  9. Visual outcome and rotational stability of open loop toric intraocular lens implantation in Indian eyes.

    PubMed

    Venkataraman, Arvind

    2013-11-01

    To assess the visual outcome and rotational stability of single-piece open loop toric Intra Ocular Lens (IOL) in a clinical setting. In a prospective study, 122 eyes of 77 patients were followed up for a period of 12 months after cataract surgery with toric open loop IOL implantation. The pre-operative markings for the position of incision and IOL placement were done under slit lamp by anterior stromal puncture. The visual acuity, refraction, and IOL position were assessed at day 1, 1 week, 1 month, 3 months, 6 months, and 12 months after surgery. The mean age of the cohort was 56 yrs (S.D. 13.88; range 16 to 87 years). The mean pre-operative cylinder of corneal astigmatism was 1.37 D. (SD 0.79, range 1.0 to 5.87 D). Mean post-operative refractive cylinder was 0.36 D (SD 0.57, range 0 to 1.50 D) at 12 months. Ninety-seven percent of the eyes were within 1 D of residual astigmatism. Ninety-four percent of patients had uncorrected visual acuity of 20/30 or better. Four eyes required IOL repositioning due to rotation. At 12 months, 96.7% of the IOLs were within 10 degrees of the target axis. There was no rotation seen after 6 months. Toric IOLs are very effective and consistent in correcting astigmatism during the cataract surgery. IOL rotation happens mostly within a month of surgery, and if significant, requires early repositioning.

  10. Three-dimensional analysis of scoliosis surgery using stereophotogrammetry

    NASA Astrophysics Data System (ADS)

    Jang, Stanley B.; Booth, Kellogg S.; Reilly, Chris W.; Sawatzky, Bonita J.; Tredwell, Stephen J.

    1994-04-01

    A new stereophotogrammetric analysis and 3D visualization allow accurate assessment of the scoliotic spine during instrumentation. Stereophoto pairs taken at each stage of the operation and robust statistical techniques are used to compute 3D transformations of the vertebrae between stages. These determine rotation, translation, goodness of fit, and overall spinal contour. A polygonal model of the spine using commercial 3D modeling package is used to produce an animation sequence of the transformation. The visualization have provided some important observation. Correction of the scoliosis is achieved largely through vertebral translation and coronal plane rotation, contrary to claims that large axial rotations are required. The animations provide valuable qualitative information for surgeons assessing the results of scoliotic correction.

  11. Virtual reality in the operating room of the future.

    PubMed

    Müller, W; Grosskopf, S; Hildebrand, A; Malkewitz, R; Ziegler, R

    1997-01-01

    In cooperation with the Max-Delbrück-Centrum/Robert-Rössle-Klinik (MDC/RRK) in Berlin, the Fraunhofer Institute for Computer Graphics is currently designing and developing a scenario for the operating room of the future. The goal of this project is to integrate new analysis, visualization and interaction tools in order to optimize and refine tumor diagnostics and therapy in combination with laser technology and remote stereoscopic video transfer. Hence, a human 3-D reference model is reconstructed using CT, MR, and anatomical cryosection images from the National Library of Medicine's Visible Human Project. Applying segmentation algorithms and surface-polygonization methods a 3-D representation is obtained. In addition, a "fly-through" the virtual patient is realized using 3-D input devices (data glove, tracking system, 6-DOF mouse). In this way, the surgeon can experience really new perspectives of the human anatomy. Moreover, using a virtual cutting plane any cut of the CT volume can be interactively placed and visualized in realtime. In conclusion, this project delivers visions for the application of effective visualization and VR systems. Commonly known as Virtual Prototyping and applied by the automotive industry long ago, this project shows, that the use of VR techniques can also prototype an operating room. After evaluating design and functionality of the virtual operating room, MDC plans to build real ORs in the near future. The use of VR techniques provides a more natural interface for the surgeon in the OR (e.g., controlling interactions by voice input). Besides preoperative planning future work will focus on supporting the surgeon in performing surgical interventions. An optimal synthesis of real and synthetic data, and the inclusion of visual, aural, and tactile senses in virtual environments can meet these requirements. This Augmented Reality could represent the environment for the surgeons of tomorrow.

  12. Depicting surgical anatomy of the porta hepatis in living donor liver transplantation.

    PubMed

    Kelly, Paul; Fung, Albert; Qu, Joy; Greig, Paul; Tait, Gordon; Jenkinson, Jodie; McGilvray, Ian; Agur, Anne

    2017-01-01

    Visualizing the complex anatomy of vascular and biliary structures of the liver on a case-by-case basis has been challenging. A living donor liver transplant (LDLT) right hepatectomy case, with focus on the porta hepatis, was used to demonstrate an innovative method to visualize anatomy with the purpose of refining preoperative planning and teaching of complex surgical procedures. The production of an animation-enhanced video consisted of many stages including the integration of pre-surgical planning; case-specific footage and 3D models of the liver and associated vasculature, reconstructed from contrast-enhanced CTs. Reconstructions of the biliary system were modeled from intraoperative cholangiograms. The distribution of the donor portal veins, hepatic arteries and bile ducts was defined from the porta hepatis intrahepatically to the point of surgical division. Each step of the surgery was enhanced with 3D animation to provide sequential and seamless visualization from pre-surgical planning to outcome. Use of visualization techniques such as transparency and overlays allows viewers not only to see the operative field, but also the origin and course of segmental branches and their spatial relationships. This novel educational approach enables integrating case-based operative footage with advanced editing techniques for visualizing not only the surgical procedure, but also complex anatomy such as vascular and biliary structures. The surgical team has found this approach to be beneficial for preoperative planning and clinical teaching, especially for complex cases. Each animation-enhanced video case is posted to the open-access Toronto Video Atlas of Surgery (TVASurg), an education resource with a global clinical and patient user base. The novel educational system described in this paper enables integrating operative footage with 3D animation and cinematic editing techniques for seamless sequential organization from pre-surgical planning to outcome.

  13. Depicting surgical anatomy of the porta hepatis in living donor liver transplantation

    PubMed Central

    Fung, Albert; Qu, Joy; Greig, Paul; Tait, Gordon; Jenkinson, Jodie; McGilvray, Ian; Agur, Anne

    2017-01-01

    Visualizing the complex anatomy of vascular and biliary structures of the liver on a case-by-case basis has been challenging. A living donor liver transplant (LDLT) right hepatectomy case, with focus on the porta hepatis, was used to demonstrate an innovative method to visualize anatomy with the purpose of refining preoperative planning and teaching of complex surgical procedures. The production of an animation-enhanced video consisted of many stages including the integration of pre-surgical planning; case-specific footage and 3D models of the liver and associated vasculature, reconstructed from contrast-enhanced CTs. Reconstructions of the biliary system were modeled from intraoperative cholangiograms. The distribution of the donor portal veins, hepatic arteries and bile ducts was defined from the porta hepatis intrahepatically to the point of surgical division. Each step of the surgery was enhanced with 3D animation to provide sequential and seamless visualization from pre-surgical planning to outcome. Use of visualization techniques such as transparency and overlays allows viewers not only to see the operative field, but also the origin and course of segmental branches and their spatial relationships. This novel educational approach enables integrating case-based operative footage with advanced editing techniques for visualizing not only the surgical procedure, but also complex anatomy such as vascular and biliary structures. The surgical team has found this approach to be beneficial for preoperative planning and clinical teaching, especially for complex cases. Each animation-enhanced video case is posted to the open-access Toronto Video Atlas of Surgery (TVASurg), an education resource with a global clinical and patient user base. The novel educational system described in this paper enables integrating operative footage with 3D animation and cinematic editing techniques for seamless sequential organization from pre-surgical planning to outcome. PMID:29078606

  14. Field evaluation of a prototype paper-based point-of-care fingerstick transaminase test.

    PubMed

    Pollock, Nira R; McGray, Sarah; Colby, Donn J; Noubary, Farzad; Nguyen, Huyen; Nguyen, The Anh; Khormaee, Sariah; Jain, Sidhartha; Hawkins, Kenneth; Kumar, Shailendra; Rolland, Jason P; Beattie, Patrick D; Chau, Nguyen V; Quang, Vo M; Barfield, Cori; Tietje, Kathy; Steele, Matt; Weigl, Bernhard H

    2013-01-01

    Monitoring for drug-induced liver injury (DILI) via serial transaminase measurements in patients on potentially hepatotoxic medications (e.g., for HIV and tuberculosis) is routine in resource-rich nations, but often unavailable in resource-limited settings. Towards enabling universal access to affordable point-of-care (POC) screening for DILI, we have performed the first field evaluation of a paper-based, microfluidic fingerstick test for rapid, semi-quantitative, visual measurement of blood alanine aminotransferase (ALT). Our objectives were to assess operational feasibility, inter-operator variability, lot variability, device failure rate, and accuracy, to inform device modification for further field testing. The paper-based ALT test was performed at POC on fingerstick samples from 600 outpatients receiving HIV treatment in Vietnam. Results, read independently by two clinic nurses, were compared with gold-standard automated (Roche Cobas) results from venipuncture samples obtained in parallel. Two device lots were used sequentially. We demonstrated high inter-operator agreement, with 96.3% (95% C.I., 94.3-97.7%) agreement in placing visual results into clinically-defined "bins" (<3x, 3-5x, and >5x upper limit of normal), >90% agreement in validity determination, and intraclass correlation coefficient of 0.89 (95% C.I., 0.87-0.91). Lot variability was observed in % invalids due to hemolysis (21.1% for Lot 1, 1.6% for Lot 2) and correlated with lots of incorporated plasma separation membranes. Invalid rates <1% were observed for all other device controls. Overall bin placement accuracy for the two readers was 84% (84.3%/83.6%). Our findings of extremely high inter-operator agreement for visual reading-obtained in a target clinical environment, as performed by local practitioners-indicate that the device operation and reading process is feasible and reproducible. Bin placement accuracy and lot-to-lot variability data identified specific targets for device optimization and material quality control. This is the first field study performed with a patterned paper-based microfluidic device and opens the door to development of similar assays for other important analytes.

  15. Global SO(3) x SO(3) x U(1) symmetry of the Hubbard model on bipartite lattices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carmelo, J.M.P., E-mail: carmelo@fisica.uminho.p; Ostlund, Stellan; Sampaio, M.J.

    2010-08-15

    In this paper the global symmetry of the Hubbard model on a bipartite lattice is found to be larger than SO(4). The model is one of the most studied many-particle quantum problems, yet except in one dimension it has no exact solution, so that there remain many open questions about its properties. Symmetry plays an important role in physics and often can be used to extract useful information on unsolved non-perturbative quantum problems. Specifically, here it is found that for on-site interaction U {ne} 0 the local SU(2) x SU(2) x U(1) gauge symmetry of the Hubbard model on amore » bipartite lattice with N{sub a}{sup D} sites and vanishing transfer integral t = 0 can be lifted to a global [SU(2) x SU(2) x U(1)]/Z{sub 2}{sup 2} = SO(3) x SO(3) x U(1) symmetry in the presence of the kinetic-energy hopping term of the Hamiltonian with t > 0. (Examples of a bipartite lattice are the D-dimensional cubic lattices of lattice constant a and edge length L = N{sub a}a for which D = 1, 2, 3,... in the number N{sub a}{sup D} of sites.) The generator of the new found hidden independent charge global U(1) symmetry, which is not related to the ordinary U(1) gauge subgroup of electromagnetism, is one half the rotated-electron number of singly occupied sites operator. Although addition of chemical-potential and magnetic-field operator terms to the model Hamiltonian lowers its symmetry, such terms commute with it. Therefore, its 4{sup N}{sub a}{sup D} energy eigenstates refer to representations of the new found global [SU(2) x SU(2) x U(1)]/Z{sub 2}{sup 2} = SO(3) x SO(3) x U(1) symmetry. Consistently, we find that for the Hubbard model on a bipartite lattice the number of independent representations of the group SO(3) x SO(3) x U(1) equals the Hilbert-space dimension 4{sup N}{sub a}{sup D}. It is confirmed elsewhere that the new found symmetry has important physical consequences.« less

  16. Design Visualization Internship Overview

    NASA Technical Reports Server (NTRS)

    Roberts, Trevor D.

    2014-01-01

    This is a report documenting the details of my work as a NASA KSC intern for the Summer Session from June 2nd to August 8th, 2014. This work was conducted within the Design Visualization Group, a Contractor staffed organization within the C1 division of the IT Directorate. The principle responsibilities of the KSC Design Visualization Group are the production of 3D simulations of NASA equipment and facilities for the purpose of planning complex operations such as hardware transportation and vehicle assembly. My role as an intern focused on aiding engineers in using 3D scanning equipment to obtain as-built measurements of NASA facilities, as well as using CATIA and DELMIA to process this data. My primary goals for this internship focused on expanding my CAD knowledge and capabilities, while also learning more about technologies I was previously unfamiliar with, such as 3D scanning. An additional goal of mine was to learn more about how NASA operates, and how the U.S. Space Program operates on a day-to-day basis. This opportunity provided me with a front-row seat to the daily maneuvers and operations of KSC and NASA as a whole. Each work day, I was able to witness, and even take part of, a small building block of the future systems that will take astronauts to other worlds. After my experiences this summer, not only can I say that my goals have been met, but also that this experience has been the highlight of my experience in higher education.

  17. Influence of Gsd for 3d City Modeling and Visualization from Aerial Imagery

    NASA Astrophysics Data System (ADS)

    Alrajhi, Muhamad; Alam, Zafare; Afroz Khan, Mohammad; Alobeid, Abdalla

    2016-06-01

    Ministry of Municipal and Rural Affairs (MOMRA), aims to establish solid infrastructure required for 3D city modelling, for decision making to set a mark in urban development. MOMRA is responsible for the large scale mapping 1:1,000; 1:2,500; 1:10,000 and 1:20,000 scales for 10cm, 20cm and 40 GSD with Aerial Triangulation data. As 3D city models are increasingly used for the presentation exploration, and evaluation of urban and architectural designs. Visualization capabilities and animations support of upcoming 3D geo-information technologies empower architects, urban planners, and authorities to visualize and analyze urban and architectural designs in the context of the existing situation. To make use of this possibility, first of all 3D city model has to be created for which MOMRA uses the Aerial Triangulation data and aerial imagery. The main concise for 3D city modelling in the Kingdom of Saudi Arabia exists due to uneven surface and undulations. Thus real time 3D visualization and interactive exploration support planning processes by providing multiple stakeholders such as decision maker, architects, urban planners, authorities, citizens or investors with a three - dimensional model. Apart from advanced visualization, these 3D city models can be helpful for dealing with natural hazards and provide various possibilities to deal with exotic conditions by better and advanced viewing technological infrastructure. Riyadh on one side is 5700m above sea level and on the other hand Abha city is 2300m, this uneven terrain represents a drastic change of surface in the Kingdom, for which 3D city models provide valuable solutions with all possible opportunities. In this research paper: influence of different GSD (Ground Sample Distance) aerial imagery with Aerial Triangulation is used for 3D visualization in different region of the Kingdom, to check which scale is more sophisticated for obtaining better results and is cost manageable, with GSD (7.5cm, 10cm, 20cm and 40cm). The comparison test is carried out in Bentley environment to check the best possible results obtained through operating different batch processes.

  18. Software Aids In Graphical Depiction Of Flow Data

    NASA Technical Reports Server (NTRS)

    Stegeman, J. D.

    1995-01-01

    Interactive Data Display System (IDDS) computer program is graphical-display program designed to assist in visualization of three-dimensional flow in turbomachinery. Grid and simulation data files in PLOT3D format required for input. Able to unwrap volumetric data cone associated with centrifugal compressor and display results in easy-to-understand two- or three-dimensional plots. IDDS provides majority of visualization and analysis capability for Integrated Computational Fluid Dynamics and Experiment (ICE) system. IDDS invoked from any subsystem, or used as stand-alone package of display software. Generates contour, vector, shaded, x-y, and carpet plots. Written in C language. Input file format used by IDDS is that of PLOT3D (COSMIC item ARC-12782).

  19. Use of micro computed-tomography and 3D printing for reverse engineering of mouse embryo nasal capsule

    NASA Astrophysics Data System (ADS)

    Tesařová, M.; Zikmund, T.; Kaucká, M.; Adameyko, I.; Jaroš, J.; Paloušek, D.; Škaroupka, D.; Kaiser, J.

    2016-03-01

    Imaging of increasingly complex cartilage in vertebrate embryos is one of the key tasks of developmental biology. This is especially important to study shape-organizing processes during initial skeletal formation and growth. Advanced imaging techniques that are reflecting biological needs give a powerful impulse to push the boundaries of biological visualization. Recently, techniques for contrasting tissues and organs have improved considerably, extending traditional 2D imaging approaches to 3D . X-ray micro computed tomography (μCT), which allows 3D imaging of biological objects including their internal structures with a resolution in the micrometer range, in combination with contrasting techniques seems to be the most suitable approach for non-destructive imaging of embryonic developing cartilage. Despite there are many software-based ways for visualization of 3D data sets, having a real solid model of the studied object might give novel opportunities to fully understand the shape-organizing processes in the developing body. In this feasibility study we demonstrated the full procedure of creating a real 3D object of mouse embryo nasal capsule, i.e. the staining, the μCT scanning combined by the advanced data processing and the 3D printing.

  20. Photogrammetric point cloud compression for tactical networks

    NASA Astrophysics Data System (ADS)

    Madison, Andrew C.; Massaro, Richard D.; Wayant, Clayton D.; Anderson, John E.; Smith, Clint B.

    2017-05-01

    We report progress toward the development of a compression schema suitable for use in the Army's Common Operating Environment (COE) tactical network. The COE facilitates the dissemination of information across all Warfighter echelons through the establishment of data standards and networking methods that coordinate the readout and control of a multitude of sensors in a common operating environment. When integrated with a robust geospatial mapping functionality, the COE enables force tracking, remote surveillance, and heightened situational awareness to Soldiers at the tactical level. Our work establishes a point cloud compression algorithm through image-based deconstruction and photogrammetric reconstruction of three-dimensional (3D) data that is suitable for dissimination within the COE. An open source visualization toolkit was used to deconstruct 3D point cloud models based on ground mobile light detection and ranging (LiDAR) into a series of images and associated metadata that can be easily transmitted on a tactical network. Stereo photogrammetric reconstruction is then conducted on the received image stream to reveal the transmitted 3D model. The reported method boasts nominal compression ratios typically on the order of 250 while retaining tactical information and accurate georegistration. Our work advances the scope of persistent intelligence, surveillance, and reconnaissance through the development of 3D visualization and data compression techniques relevant to the tactical operations environment.

  1. SCEC-VDO: A New 3-Dimensional Visualization and Movie Making Software for Earth Science Data

    NASA Astrophysics Data System (ADS)

    Milner, K. R.; Sanskriti, F.; Yu, J.; Callaghan, S.; Maechling, P. J.; Jordan, T. H.

    2016-12-01

    Researchers and undergraduate interns at the Southern California Earthquake Center (SCEC) have created a new 3-dimensional (3D) visualization software tool called SCEC Virtual Display of Objects (SCEC-VDO). SCEC-VDO is written in Java and uses the Visualization Toolkit (VTK) backend to render 3D content. SCEC-VDO offers advantages over existing 3D visualization software for viewing georeferenced data beneath the Earth's surface. Many popular visualization packages, such as Google Earth, restrict the user to views of the Earth from above, obstructing views of geological features such as faults and earthquake hypocenters at depth. SCEC-VDO allows the user to view data both above and below the Earth's surface at any angle. It includes tools for viewing global earthquakes from the U.S. Geological Survey, faults from the SCEC Community Fault Model, and results from the latest SCEC models of earthquake hazards in California including UCERF3 and RSQSim. Its object-oriented plugin architecture allows for the easy integration of new regional and global datasets, regardless of the science domain. SCEC-VDO also features rich animation capabilities, allowing users to build a timeline with keyframes of camera position and displayed data. The software is built with the concept of statefulness, allowing for reproducibility and collaboration using an xml file. A prior version of SCEC-VDO, which began development in 2005 under the SCEC Undergraduate Studies in Earthquake Information Technology internship, used the now unsupported Java3D library. Replacing Java3D with the widely supported and actively developed VTK libraries not only ensures that SCEC-VDO can continue to function for years to come, but allows for the export of 3D scenes to web viewers and popular software such as Paraview. SCEC-VDO runs on all recent 64-bit Windows, Mac OS X, and Linux systems with Java 8 or later. More information, including downloads, tutorials, and example movies created fully within SCEC-VDO is available here: http://scecvdo.usc.edu

  2. 2011 NASA Lunabotics Mining Competition for Universities: Results and Lessons Learned

    NASA Technical Reports Server (NTRS)

    Mueller, Robert P.; Murphy, Gloria A.

    2011-01-01

    Overview: Design, build & compete remote controlled robot (Lunabot). Excavate Black Point 1 (BP-1) Lunar Simulant. Deposit minimum of 10 kg of BP-1 within 15 minutes $5000, $2500, $1000 Scholarships for most BP-1 excavated. May 23-28, 2011. Kennedy Space Center, FL. International Teams Allowed for the First Time. What is a Lunabot? a) Robot Controlled Remotely or Autonomously. b) Visual and Auditory Isolation from Operator. c) Excavates Black Point 1 (BP-l) Simulant. d) Weight Limit - 80 kg. e)Dimension Limits -1.5m width x .75m length x 2m height. f) Designed, Built and Tested by University Student Teams.

  3. Atlas and feature based 3D pathway visualization enhancement for skull base pre-operative fast planning from head CT

    NASA Astrophysics Data System (ADS)

    Aghdasi, Nava; Li, Yangming; Berens, Angelique; Moe, Kris S.; Bly, Randall A.; Hannaford, Blake

    2015-03-01

    Minimally invasive neuroendoscopic surgery provides an alternative to open craniotomy for many skull base lesions. These techniques provides a great benefit to the patient through shorter ICU stays, decreased post-operative pain and quicker return to baseline function. However, density of critical neurovascular structures at the skull base makes planning for these procedures highly complex. Furthermore, additional surgical portals are often used to improve visualization and instrument access, which adds to the complexity of pre-operative planning. Surgical approach planning is currently limited and typically involves review of 2D axial, coronal, and sagittal CT and MRI images. In addition, skull base surgeons manually change the visualization effect to review all possible approaches to the target lesion and achieve an optimal surgical plan. This cumbersome process relies heavily on surgeon experience and it does not allow for 3D visualization. In this paper, we describe a rapid pre-operative planning system for skull base surgery using the following two novel concepts: importance-based highlight and mobile portal. With this innovation, critical areas in the 3D CT model are highlighted based on segmentation results. Mobile portals allow surgeons to review multiple potential entry portals in real-time with improved visualization of critical structures located inside the pathway. To achieve this we used the following methods: (1) novel bone-only atlases were manually generated, (2) orbits and the center of the skull serve as features to quickly pre-align the patient's scan with the atlas, (3) deformable registration technique was used for fine alignment, (4) surgical importance was assigned to each voxel according to a surgical dictionary, and (5) pre-defined transfer function was applied to the processed data to highlight important structures. The proposed idea was fully implemented as independent planning software and additional data are used for verification and validation. The experimental results show: (1) the proposed methods provided greatly improved planning efficiency while optimal surgical plans were successfully achieved, (2) the proposed methods successfully highlighted important structures and facilitated planning, (3) the proposed methods require shorter processing time than classical segmentation algorithms, and (4) these methods can be used to improve surgical safety for surgical robots.

  4. An improved three-dimension reconstruction method based on guided filter and Delaunay

    NASA Astrophysics Data System (ADS)

    Liu, Yilin; Su, Xiu; Liang, Haitao; Xu, Huaiyuan; Wang, Yi; Chen, Xiaodong

    2018-01-01

    Binocular stereo vision is becoming a research hotspot in the area of image processing. Based on traditional adaptive-weight stereo matching algorithm, we improve the cost volume by averaging the AD (Absolute Difference) of RGB color channels and adding x-derivative of the grayscale image to get the cost volume. Then we use guided filter in the cost aggregation step and weighted median filter for post-processing to address the edge problem. In order to get the location in real space, we combine the deep information with the camera calibration to project each pixel in 2D image to 3D coordinate matrix. We add the concept of projection to region-growing algorithm for surface reconstruction, its specific operation is to project all the points to a 2D plane through the normals of clouds and return the results back to 3D space according to these connection relationship among the points in 2D plane. During the triangulation in 2D plane, we use Delaunay algorithm because it has optimal quality of mesh. We configure OpenCV and pcl on Visual Studio for testing, and the experimental results show that the proposed algorithm have higher computational accuracy of disparity and can realize the details of the real mesh model.

  5. NanoXCT: a novel technique to probe the internal architecture of pharmaceutical particles.

    PubMed

    Wong, Jennifer; D'Sa, Dexter; Foley, Matthew; Chan, John Gar Yan; Chan, Hak-Kim

    2014-11-01

    To demonstrate the novel application of nano X-ray computed tomography (NanoXCT) for visualizing and quantifying the internal structures of pharmaceutical particles. An Xradia NanoXCT-100, which produces ultra high-resolution and non-destructive imaging that can be reconstructed in three-dimensions (3D), was used to characterize several pharmaceutical particles. Depending on the particle size of the sample, NanoXCT was operated in Zernike Phase Contrast (ZPC) mode using either: 1) large field of view (LFOV), which has a two-dimensional (2D) spatial resolution of 172 nm; or 2) high resolution (HRES) that has a resolution of 43.7 nm. Various pharmaceutical particles with different physicochemical properties were investigated, including raw (2-hydroxypropyl)-beta-cyclodextrin (HβCD), poly (lactic-co-glycolic) acid (PLGA) microparticles, and spray-dried particles that included smooth and nanomatrix bovine serum albumin (BSA), lipid-based carriers, and mannitol. Both raw HβCD and PLGA microparticles had a network of voids, whereas spray-dried smooth BSA and mannitol generally had a single void. Lipid-based carriers and nanomatrix BSA particles resulted in low quality images due to high noise-to-signal ratio. The quantitative capabilities of NanoXCT were also demonstrated where spray-dried mannitol was found to have an average void volume of 0.117 ± 0.247 μm(3) and average void-to-material percentage of 3.5%. The single PLGA particle had values of 1993 μm(3) and 59.3%, respectively. This study reports the first series of non-destructive 3D visualizations of inhalable pharmaceutical particles. Overall, NanoXCT presents a powerful tool to dissect and observe the interior of pharmaceutical particles, including those of a respirable size.

  6. Comparison of two methods of visual magnification for removal of adhesive flash during bracket placement using two types of orthodontic bonding agents

    PubMed Central

    Alencar, Estefania Queiroga de Santana e; Nobrega, Maria de Lourdes Martins; Dametto, Fabio Roberto; dos Santos, Patrícia Bittencourt Dutra; Pinheiro, Fabio Henrique de Sá Leitão

    2016-01-01

    ABSTRACT Objective: This study aimed to evaluate the effectiveness of two methods of visual magnification (operating microscope and light head magnifying glass) for removal of composite flash around orthodontic metal brackets. Material and Methods: Brackets were bonded in the center of the clinical crown of sixty well-preserved human premolars. Half of the sample was bonded with conventional Transbond XT (3M Unitek TM, USA), whereas the other half was bonded with Transbond TM Plus Color Change (3M Unitek TM, USA). For each type of composite, the choice of method to remove the flash was determined by randomly distributing the teeth into the following subgroups: A (removal by naked eye, n = 10), B (removal with the aid of light head magnifying glass, under 4x magnification, n = 10), and C (removal with the aid of an operating microscope, under 40x magnification, n = 10). Brackets were debonded and teeth taken to a scanning electron microscope (SS-x-550, Shimadzu, Japan) for visualization of their buccal surface. Quantification of composite flash was performed with Image Pro Plus software, and values were compared by Kruskal-Wallis test and Dunn’s post-hoc test at 5% significance level. Results: Removal of pigmented orthodontic adhesive with the aid of light head magnifying glass proved, in general, to be advantageous in comparison to all other methods. Conclusion: There was no advantage in using Transbond TM Plus Color Change alone. Further studies are necessary to draw a more definitive conclusion in regards to the benefits of using an operating microscope. PMID:28125139

  7. [Application of 3D printing and computer-assisted surgical simulation in preoperative planning for acetabular fracture].

    PubMed

    Liu, Xin; Zeng, Can-Jun; Lu, Jian-Sen; Lin, Xu-Chen; Huang, Hua-Jun; Tan, Xin-Yu; Cai, Dao-Zhang

    2017-03-20

    To evaluate the feasibility and effectiveness of using 3D printing and computer-assisted surgical simulation in preoperative planning for acetabular fractures. A retrospective analysis was performed in 53 patients with pelvic fracture, who underwent surgical treatment between September, 2013 and December, 2015 with complete follow-up data. Among them, 19 patients were treated with CT three-dimensional reconstruction, computer-assisted virtual reset internal fixation, 3D model printing, and personalized surgery simulation before surgery (3D group), and 34 patients underwent routine preoperative examination (conventional group). The intraoperative blood loss, transfusion volume, times of intraoperative X-ray, operation time, Matta score and Merle D' Aubigne & Postel score were recorded in the 2 groups. Preoperative planning and postoperative outcomes in the two groups were compared. All the operations were completed successfully. In 3D group, significantly less intraoperative blood loss, transfusion volume, fewer times of X-ray, and shortened operation time were recorded compared with those in the conventional group (P<0.05). According to the Matta scores, excellent or good fracture reduction was achieved in 94.7% (18/19) of the patients in 3D group and in 82.4% (28/34) of the patients in conventional group; the rates of excellent and good hip function at the final follow-up were 89.5% (17/19) in the 3D group and 85.3% (29/34) in the conventional group (P>0.05). In the 3D group, the actual internal fixation well matched the preoperative design. 3D printing and computer-assisted surgical simulation for preoperative planning is feasible and accurate for management of acetabular fracture and can effectively improve the operation efficiency.

  8. Three-Dimensional Visualization with Large Data Sets: A Simulation of Spreading Cortical Depression in Human Brain

    PubMed Central

    Ertürk, Korhan Levent; Şengül, Gökhan

    2012-01-01

    We developed 3D simulation software of human organs/tissues; we developed a database to store the related data, a data management system to manage the created data, and a metadata system for the management of data. This approach provides two benefits: first of all the developed system does not require to keep the patient's/subject's medical images on the system, providing less memory usage. Besides the system also provides 3D simulation and modification options, which will help clinicians to use necessary tools for visualization and modification operations. The developed system is tested in a case study, in which a 3D human brain model is created and simulated from 2D MRI images of a human brain, and we extended the 3D model to include the spreading cortical depression (SCD) wave front, which is an electrical phoneme that is believed to cause the migraine. PMID:23258956

  9. A Web-based Visualization System for Three Dimensional Geological Model using Open GIS

    NASA Astrophysics Data System (ADS)

    Nemoto, T.; Masumoto, S.; Nonogaki, S.

    2017-12-01

    A three dimensional geological model is an important information in various fields such as environmental assessment, urban planning, resource development, waste management and disaster mitigation. In this study, we have developed a web-based visualization system for 3D geological model using free and open source software. The system has been successfully implemented by integrating web mapping engine MapServer and geographic information system GRASS. MapServer plays a role of mapping horizontal cross sections of 3D geological model and a topographic map. GRASS provides the core components for management, analysis and image processing of the geological model. Online access to GRASS functions has been enabled using PyWPS that is an implementation of WPS (Web Processing Service) Open Geospatial Consortium (OGC) standard. The system has two main functions. Two dimensional visualization function allows users to generate horizontal and vertical cross sections of 3D geological model. These images are delivered via WMS (Web Map Service) and WPS OGC standards. Horizontal cross sections are overlaid on the topographic map. A vertical cross section is generated by clicking a start point and an end point on the map. Three dimensional visualization function allows users to visualize geological boundary surfaces and a panel diagram. The user can visualize them from various angles by mouse operation. WebGL is utilized for 3D visualization. WebGL is a web technology that brings hardware-accelerated 3D graphics to the browser without installing additional software. The geological boundary surfaces can be downloaded to incorporate the geologic structure in a design on CAD and model for various simulations. This study was supported by JSPS KAKENHI Grant Number JP16K00158.

  10. Evaluation of TanDEM-X DEMs on selected Brazilian sites: Comparison with SRTM, ASTER GDEM and ALOS AW3D30

    NASA Astrophysics Data System (ADS)

    Grohmann, Carlos H.

    2018-06-01

    A first assessment of the TanDEM-X DEMs over Brazilian territory is presented through a comparison with SRTM, ASTER GDEM and ALOS AW3D30 DEMs in seven study areas with distinct geomorphological contexts, vegetation coverage and land use. Visual analysis and elevation histograms point to a finer effective spatial resolution of TanDEM-X compared to SRTM and ASTER GDEM. In areas of open vegetation, TanDEM-X lower elevations indicate a better penetration of the radar signal. DEMs of differences (DoDs) allowed the identification of issues inherent to the production methods of the analyzed DEMs, such as mast oscillations in SRTM data and mismatch between adjacent scenes in ASTER GDEM and ALOS AW3D30. A systematic difference in elevations between TanDEM-X 12m, TanDEM-X 30m and SRTM was observed in the steep slopes of the coastal ranges, related to the moving-window process used to resample the 12m data to a 30m pixel size. Due its simplicity, it is strongly recommended to produce a DoD with SRTM before using ASTER GDEM or ALOS AW3D30 in any analysis, to evaluate if the area of interest is affected by these problems. The DoDs also highlighted changes in land use in the time span between the acquisition of SRTM (2000) and TanDEM-X (2013) data, whether by natural causes or by human interference in the environment.

  11. 3D Imaging of Microbial Biofilms: Integration of Synchrotron Imaging and an Interactive Visualization Interface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas, Mathew; Marshall, Matthew J.; Miller, Erin A.

    2014-08-26

    Understanding the interactions of structured communities known as “biofilms” and other complex matrixes is possible through the X-ray micro tomography imaging of the biofilms. Feature detection and image processing for this type of data focuses on efficiently identifying and segmenting biofilms and bacteria in the datasets. The datasets are very large and often require manual interventions due to low contrast between objects and high noise levels. Thus new software is required for the effectual interpretation and analysis of the data. This work specifies the evolution and application of the ability to analyze and visualize high resolution X-ray micro tomography datasets.

  12. Distributed Observer Network

    NASA Technical Reports Server (NTRS)

    2008-01-01

    NASA s advanced visual simulations are essential for analyses associated with life cycle planning, design, training, testing, operations, and evaluation. Kennedy Space Center, in particular, uses simulations for ground services and space exploration planning in an effort to reduce risk and costs while improving safety and performance. However, it has been difficult to circulate and share the results of simulation tools among the field centers, and distance and travel expenses have made timely collaboration even harder. In response, NASA joined with Valador Inc. to develop the Distributed Observer Network (DON), a collaborative environment that leverages game technology to bring 3-D simulations to conventional desktop and laptop computers. DON enables teams of engineers working on design and operations to view and collaborate on 3-D representations of data generated by authoritative tools. DON takes models and telemetry from these sources and, using commercial game engine technology, displays the simulation results in a 3-D visual environment. Multiple widely dispersed users, working individually or in groups, can view and analyze simulation results on desktop and laptop computers in real time.

  13. Rover Sequencing and Visualization Program

    NASA Technical Reports Server (NTRS)

    Cooper, Brian; Hartman, Frank; Maxwell, Scott; Yen, Jeng; Wright, John; Balacuit, Carlos

    2005-01-01

    The Rover Sequencing and Visualization Program (RSVP) is the software tool for use in the Mars Exploration Rover (MER) mission for planning rover operations and generating command sequences for accomplishing those operations. RSVP combines three-dimensional (3D) visualization for immersive exploration of the operations area, stereoscopic image display for high-resolution examination of the downlinked imagery, and a sophisticated command-sequence editing tool for analysis and completion of the sequences. RSVP is linked with actual flight-code modules for operations rehearsal to provide feedback on the expected behavior of the rover prior to committing to a particular sequence. Playback tools allow for review of both rehearsed rover behavior and downlinked results of actual rover operations. These can be displayed simultaneously for comparison of rehearsed and actual activities for verification. The primary inputs to RSVP are downlink data products from the Operations Storage Server (OSS) and activity plans generated by the science team. The activity plans are high-level goals for the next day s activities. The downlink data products include imagery, terrain models, and telemetered engineering data on rover activities and state. The Rover Sequence Editor (RoSE) component of RSVP performs activity expansion to command sequences, command creation and editing with setting of command parameters, and viewing and management of rover resources. The HyperDrive component of RSVP performs 2D and 3D visualization of the rover s environment, graphical and animated review of rover-predicted and telemetered state, and creation and editing of command sequences related to mobility and Instrument Deployment Device (IDD) operations. Additionally, RoSE and HyperDrive together evaluate command sequences for potential violations of flight and safety rules. The products of RSVP include command sequences for uplink that are stored in the Distributed Object Manager (DOM) and predicted rover state histories stored in the OSS for comparison and validation of downlinked telemetry. The majority of components comprising RSVP utilize the MER command and activity dictionaries to automatically customize the system for MER activities. Thus, RSVP, being highly data driven, may be tailored to other missions with minimal effort. In addition, RSVP uses a distributed, message-passing architecture to allow multitasking, and collaborative visualization and sequence development by scattered team members.

  14. Direct Visualization of Orbital Flipping in Volborthite by Charge Density Analysis Using Detwinned Data

    NASA Astrophysics Data System (ADS)

    Sugawara, Kento; Sugimoto, Kunihisa; Fujii, Tatsuya; Higuchi, Takafumi; Katayama, Naoyuki; Okamoto, Yoshihiko; Sawa, Hiroshi

    2018-02-01

    The distribution of d-orbital valence electrons in volborthite [Cu3V2O7(OH)2 • 2H2O] was investigated by charge density analysis of the multipole model refinement. Diffraction data were obtained by synchrotron radiation single-crystal X-ray diffraction experiments. Data reduction by detwinning of the multiple structural domains was performed using our developed software. In this study, using high-quality data, we demonstrated that the water molecules in volborthite can be located by the hydrogen bonding in cavities that consist of Kagome lattice layers of CuO4(OH)2 and pillars of V2O7. Final multipole refinements before and after the structural phase transition directly visualized the deformation electron density of the valence electrons. We successfully directly visualized the orbital flipping of the d-orbital dx2-y2, which is the highest level of 3d orbitals occupied by d9 electrons in volborthite. The developed techniques and software can be employed for investigations of structural properties of systems with multiple structural domains.

  15. [Analysis of the Effect of Non-phacoemulsification Cataract Operation on Corneal Endothelial Cell Nucleus Division].

    PubMed

    Huang, Zufeng; Miao, Xiaoqing

    2015-09-01

    To investigate the effect of non-phacoemulsification cataract operation in two different patterns of nucleus delivery on the quantity and morphology of corneal endothelial cells and postoperative visual acuity. Forty patients diagnosed with cataract underwent cataract surgery and were assigned into the direct nuclear delivery and semi-nuclear delivery groups. Lens density was measured and divided into the hard and soft lenses according to Emery-little lens nucleus grading system. Non-phacoemulsification cataract operation was performed. At 3 d after surgery, the quantity and morphology of corneal endothelium were counted and observed under corneal endothelial microscope. During 3-month postoperative follow-up, the endothelial cell loss rate, morphological changes and visual acuity were compared among four groups. Corneal endothelial cell loss rate in the direct delivery of hard nucleus group significantly differed from those in the other three groups before and 3 months after operation (P < 0.01), whereas no statistical significance was found among the direct delivery of soft nucleus, semi-delivery of hard nucleus and semi-delivery soft nucleus groups (all P > 0.05). Preoperative and postoperative 2-d visual acuity did not differ between the semi-delivery of hard nucleus and direct delivery of soft nucleus groups (P = 0.49), significantly differed from those in the semi-delivery of soft nucleus (P = 0.03) and direct delivery of hard nucleus groups (P = 0.14). Visual acuity at postoperative four months did not differ among four groups (P = 0.067). During non-phacoemulsification cataract surgery, direct delivery of hard nucleus caused severe injury to corneal endothelium and semi-delivery of soft nucleus yielded mild corneal endothelial injury. Slight corneal endothelial injury exerted no apparent effect upon visual acuity and corneal endothelial morphology at three months after surgery.

  16. Effectiveness of the 3D Monitor System for Medical Education During Neurosurgical Operation.

    PubMed

    Wanibuchi, Masahiko; Komatsu, Katsuya; Akiyama, Yukinori; Mikami, Takeshi; Mikuni, Nobuhiro

    2018-01-01

    Three-dimensional (3D) graphics are used in the medical field, especially during surgery. Although 3D monitoring is useful for medical education, its effectiveness needs to be objectively evaluated. The aim of this study was to investigate the efficacy of 3D monitoring in the surgical education of medical students. A questionnaire on high-definition 3D monitoring was given to fifth-year medical students in a 6-year program. Sixty-four students wore polarized glasses and observed a microsurgical operation through a 3D monitor. The questionnaire contained questions on stereopsis, neurosurgical interest, visual impact, comprehension of surgical anatomy and procedures, optical sharpness, active learning enhancement, and eye exhaustion. These parameters were evaluated on a 5-point scale that spanned negative and positive scores. The average score of each parameter ranged from 3.13 to 3.78, except for eye exhaustion, which was 0.88. The items for which the students reported positive perceptions (scores of 4 or 5) were stereopsis (67.2% of students), neurosurgical interest (62.5%), visual impact and optical sharpness (60.9% for both), active learning enhancement (57.8%), and comprehension of surgical anatomy (50.0%) and procedures (42.2%). By contrast, only eye exhaustion was evaluated negatively (26.6%). The use of 3D monitoring systems in medical education offers the advantage of stereopsis and contributes to surgical training. However, improvements are required to decrease eye exhaustion. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Quantitative Visualization of Salt Concentration Distributions in Lithium-Ion Battery Electrolytes during Battery Operation Using X-ray Phase Imaging.

    PubMed

    Takamatsu, Daiko; Yoneyama, Akio; Asari, Yusuke; Hirano, Tatsumi

    2018-02-07

    A fundamental understanding of concentrations of salts in lithium-ion battery electrolytes during battery operation is important for optimal operation and design of lithium-ion batteries. However, there are few techniques that can be used to quantitatively characterize salt concentration distributions in the electrolytes during battery operation. In this paper, we demonstrate that in operando X-ray phase imaging can quantitatively visualize the salt concentration distributions that arise in electrolytes during battery operation. From quantitative evaluation of the concentration distributions at steady states, we obtained the salt diffusivities in electrolytes with different initial salt concentrations. Because of no restriction on samples and high temporal and spatial resolutions, X-ray phase imaging will be a versatile technique for evaluating electrolytes, both aqueous and nonaqueous, of many electrochemical systems.

  18. 3D MRI Modeling of Thin and Spatially Complex Soft Tissue Structures without Shrinkage: Lamprey Myosepta as an Example.

    PubMed

    Wood, Bradley M; Jia, Guang; Carmichael, Owen; McKlveen, Kevin; Homberger, Dominique G

    2018-05-12

    3D imaging techniques enable the non-destructive analysis and modeling of complex structures. Among these, MRI exhibits good soft tissue contrast, but is currently less commonly used for non-clinical research than x-ray CT, even though the latter requires contrast-staining that shrinks and distorts soft tissues. When the objective is the creation of a realistic and complete 3D model of soft tissue structures, MRI data are more demanding to acquire and visualize and require extensive post-processing because they comprise non-cubic voxels with dimensions that represent a trade-off between tissue contrast and image resolution. Therefore, thin soft tissue structures with complex spatial configurations are not always visible in a single MRI dataset, so that standard segmentation techniques are not sufficient for their complete visualization. By using the example of the thin and spatially complex connective tissue myosepta in lampreys, we developed a workflow protocol for the selection of the appropriate parameters for the acquisition of MRI data and for the visualization and 3D modeling of soft tissue structures. This protocol includes a novel recursive segmentation technique for supplementing missing data in one dataset with data from another dataset to produce realistic and complete 3D models. Such 3D models are needed for the modeling of dynamic processes, such as the biomechanics of fish locomotion. However, our methodology is applicable to the visualization of any thin soft tissue structures with complex spatial configurations, such as fasciae, aponeuroses, and small blood vessels and nerves, for clinical research and the further exploration of tensegrity. This article is protected by copyright. All rights reserved. © 2018 Wiley Periodicals, Inc.

  19. Visual outcome and rotational stability of open loop toric intraocular lens implantation in Indian eyes

    PubMed Central

    Venkataraman, Arvind; Kalpana

    2013-01-01

    Purpose: To assess the visual outcome and rotational stability of single-piece open loop toric Intra Ocular Lens (IOL) in a clinical setting. Materials and Methods: In a prospective study, 122 eyes of 77 patients were followed up for a period of 12 months after cataract surgery with toric open loop IOL implantation. The pre-operative markings for the position of incision and IOL placement were done under slit lamp by anterior stromal puncture. The visual acuity, refraction, and IOL position were assessed at day 1, 1 week, 1 month, 3 months, 6 months, and 12 months after surgery. Results: The mean age of the cohort was 56 yrs (S.D. 13.88; range 16 to 87 years). The mean pre-operative cylinder of corneal astigmatism was 1.37 D. (SD 0.79, range 1.0 to 5.87 D). Mean post-operative refractive cylinder was 0.36 D (SD 0.57, range 0 to 1.50 D) at 12 months. Ninety-seven percent of the eyes were within 1 D of residual astigmatism. Ninety-four percent of patients had uncorrected visual acuity of 20/30 or better. Four eyes required IOL repositioning due to rotation. At 12 months, 96.7% of the IOLs were within 10 degrees of the target axis. There was no rotation seen after 6 months. Conclusion: Toric IOLs are very effective and consistent in correcting astigmatism during the cataract surgery. IOL rotation happens mostly within a month of surgery, and if significant, requires early repositioning. PMID:24343593

  20. 3D nanoscale imaging of the yeast, Schizosaccharomyces pombe, by full-field transmission X-ray microscopy at 5.4 keV.

    PubMed

    Chen, Jie; Yang, Yunhao; Zhang, Xiaobo; Andrews, Joy C; Pianetta, Piero; Guan, Yong; Liu, Gang; Xiong, Ying; Wu, Ziyu; Tian, Yangchao

    2010-07-01

    Three-dimensional (3D) nanoscale structures of the fission yeast, Schizosaccharomyces pombe, can be obtained by full-field transmission hard X-ray microscopy with 30 nm resolution using synchrotron radiation sources. Sample preparation is relatively simple and the samples are portable across various imaging environments, allowing for high-throughput sample screening. The yeast cells were fixed and double-stained with Reynold's lead citrate and uranyl acetate. We performed both absorption contrast and Zernike phase contrast imaging on these cells in order to test this method. The membranes, nucleus, and subcellular organelles of the cells were clearly visualized using absorption contrast mode. The X-ray images of the cells could be used to study the spatial distributions of the organelles in the cells. These results show unique structural information, demonstrating that hard X-ray microscopy is a complementary method for imaging and analyzing biological samples.

  1. HipMatch: an object-oriented cross-platform program for accurate determination of cup orientation using 2D-3D registration of single standard X-ray radiograph and a CT volume.

    PubMed

    Zheng, Guoyan; Zhang, Xuan; Steppacher, Simon D; Murphy, Stephen B; Siebenrock, Klaus A; Tannast, Moritz

    2009-09-01

    The widely used procedure of evaluation of cup orientation following total hip arthroplasty using single standard anteroposterior (AP) radiograph is known inaccurate, largely due to the wide variability in individual pelvic orientation relative to X-ray plate. 2D-3D image registration methods have been introduced for an accurate determination of the post-operative cup alignment with respect to an anatomical reference extracted from the CT data. Although encouraging results have been reported, their extensive usage in clinical routine is still limited. This may be explained by their requirement of a CAD model of the prosthesis, which is often difficult to be organized from the manufacturer due to the proprietary issue, and by their requirement of either multiple radiographs or a radiograph-specific calibration, both of which are not available for most retrospective studies. To address these issues, we developed and validated an object-oriented cross-platform program called "HipMatch" where a hybrid 2D-3D registration scheme combining an iterative landmark-to-ray registration with a 2D-3D intensity-based registration was implemented to estimate a rigid transformation between a pre-operative CT volume and the post-operative X-ray radiograph for a precise estimation of cup alignment. No CAD model of the prosthesis is required. Quantitative and qualitative results evaluated on cadaveric and clinical datasets are given, which indicate the robustness and the accuracy of the program. HipMatch is written in object-oriented programming language C++ using cross-platform software Qt (TrollTech, Oslo, Norway), VTK, and Coin3D and is transportable to any platform.

  2. 3D reconstruction and spatial auralization of the "Painted Dolmen" of Antelas

    NASA Astrophysics Data System (ADS)

    Dias, Paulo; Campos, Guilherme; Santos, Vítor; Casaleiro, Ricardo; Seco, Ricardo; Sousa Santos, Beatriz

    2008-02-01

    This paper presents preliminary results on the development of a 3D audiovisual model of the Anta Pintada (painted dolmen) of Antelas, a Neolithic chamber tomb located in Oliveira de Frades and listed as Portuguese national monument. The final aim of the project is to create a highly accurate Virtual Reality (VR) model of this unique archaeological site, capable of providing not only visual but also acoustic immersion based on its actual geometry and physical properties. The project started in May 2006 with in situ data acquisition. The 3D geometry of the chamber was captured using a Laser Range Finder. In order to combine the different scans into a complete 3D visual model, reconstruction software based on the Iterative Closest Point (ICP) algorithm was developed using the Visualization Toolkit (VTK). This software computes the boundaries of the room on a 3D uniform grid and populates its interior with "free-space nodes", through an iterative algorithm operating like a torchlight illuminating a dark room. The envelope of the resulting set of "free-space nodes" is used to generate a 3D iso-surface approximating the interior shape of the chamber. Each polygon of this surface is then assigned the acoustic absorption coefficient of the corresponding boundary material. A 3D audiovisual model operating in real-time was developed for a VR Environment comprising head-mounted display (HMD) I-glasses SVGAPro, an orientation sensor (tracker) InterTrax 2 with 3 Degrees Of Freedom (3DOF) and stereo headphones. The auralisation software is based on a geometric model. This constitutes a first approach, since geometric acoustics have well-known limitations in rooms with irregular surfaces. The immediate advantage lies in their inherent computational efficiency, which allows real-time operation. The program computes the early reflections forming the initial part of the chamber's impulse response (IR), which carry the most significant cues for source localisation. These early reflections are processed through Head Related Transfer Functions (HRTF) updated in real-time according to the orientation of the user's head, so that sound waves appear to come from the correct location in space, in agreement with the visual scene. The late-reverberation tail of the IR is generated by an algorithm designed to match the reverberation time of the chamber, calculated from the actual acoustic absorption coefficients of its surfaces. The sound output to the headphones is obtained by convolving the IR with anechoic recordings of the virtual audio source.

  3. 3D PATTERN OF BRAIN ABNORMALITIES IN FRAGILE X SYNDROME VISUALIZED USING TENSOR-BASED MORPHOMETRY

    PubMed Central

    Lee, Agatha D.; Leow, Alex D.; Lu, Allen; Reiss, Allan L.; Hall, Scott; Chiang, Ming-Chang; Toga, Arthur W.; Thompson, Paul M.

    2007-01-01

    Fragile X syndrome (FraX), a genetic neurodevelopmental disorder, results in impaired cognition with particular deficits in executive function and visuo-spatial skills. Here we report the first detailed 3D maps of the effects of the Fragile X mutation on brain structure, using tensor-based morphometry. TBM visualizes structural brain deficits automatically, without time-consuming specification of regions-of-interest. We compared 36 subjects with FraX (age: 14.66+/−1.58SD, 18 females/18 males), and 33 age-matched healthy controls (age: 14.67+/−2.2SD, 17 females/16 males), using high-dimensional elastic image registration. All 69 subjects' 3D T1-weighted brain MRIs were spatially deformed to match a high-resolution single-subject average MRI scan in ICBM space, whose geometry was optimized to produce a minimal deformation target. Maps of the local Jacobian determinant (expansion factor) were computed from the deformation fields. Statistical maps showed increased caudate (10% higher; p=0.001) and lateral ventricle volumes (19% higher; p=0.003), and trend-level parietal and temporal white matter excesses (10% higher locally; p=0.04). In affected females, volume abnormalities correlated with reduction in systemically measured levels of the fragile X mental retardation protein (FMRP; Spearman's r<−0.5 locally). Decreased FMRP correlated with ventricular expansion (p=0.042; permutation test), and anterior cingulate tissue reductions (p=0.0026; permutation test) supporting theories that FMRP is required for normal dendritic pruning in fronto-striatal-limbic pathways. No sex differences were found; findings were confirmed using traditional volumetric measures in regions of interest. Deficit patterns were replicated using Lie group statistics optimized for tensor-valued data. Investigation of how these anomalies emerge over time will accelerate our understanding of FraX and its treatment. PMID:17161622

  4. Shrinkage of X cells in the lateral geniculate nucleus after monocular deprivation revealed by FoxP2 labeling.

    PubMed

    Duffy, Kevin R; Holman, Kaitlyn D; Mitchell, Donald E

    2014-05-01

    The parallel processing of visual features by distinct neuron populations is a central characteristic of the mammalian visual system. In the A laminae of the cat dorsal lateral geniculate nucleus (dLGN), parallel processing streams originate from two principal neuron types, called X and Y cells. Disruption of visual experience early in life by monocular deprivation has been shown to alter the structure and function of Y cells, but the extent to which deprivation influences X cells remains less clear. A transcription factor, FoxP2, has recently been shown to selectively label X cells in the ferret dLGN and thus provides an opportunity to examine whether monocular deprivation alters the soma size of X cells. In this study, FoxP2 labeling was examined in the dLGN of normal and monocularly deprived cats. The characteristics of neurons labeled for FoxP2 were consistent with FoxP2 being a marker for X cells in the cat dLGN. Monocular deprivation for either a short (7 days) or long (7 weeks) duration did not alter the density of FoxP2-positive neurons between nondeprived and deprived dLGN layers. However, for each deprived animal examined, measurement of the cross-sectional area of FoxP2-positive neurons (X cells) revealed that within deprived layers, X cells were smaller by approximately 20% after 7 days of deprivation, and by approximately 28% after 7 weeks of deprivation. The observed alteration to the cross-sectional area of X cells indicates that perturbation of this major pathway contributes to the functional impairments that develop from monocular deprivation.

  5. OPERATION DOMINIC. FISH BOWL SERIES. Project Officer’s Report. Project 8A.3. Close-In Thermal and X-Ray Vulnerability Measurements--Shots Blue Gill and King Fish

    DTIC Science & Technology

    1985-09-01

    QDC hLt umi ^ POR.2037 (WT-2037)(EX) VOLUME 1 EXTRACTED VERSION OPERATION DOMINIC, FISH BOWL SERIES Project Officer’s Report—Project 8A.3...Close-In Thermal and X-ray Vulnerability Measurements—Shots Blue Gill and King Fish F. D. Adams, Project Officer Flight Dynamics Laboratory Wright...version of POR-2037 (WT-2037), Volume 1, OPERATION DOMINIC; Fish Bowl Series, Project 8A. 3. Approved for public release; distribution is unlimited

  6. 3D-PTV around Operational Wind Turbines

    NASA Astrophysics Data System (ADS)

    Brownstein, Ian; Dabiri, John

    2016-11-01

    Laboratory studies and numerical simulations of wind turbines are typically constrained in how they can inform operational turbine behavior. Laboratory experiments are usually unable to match both pertinent parameters of full-scale wind turbines, the Reynolds number (Re) and tip speed ratio, using scaled-down models. Additionally, numerical simulations of the flow around wind turbines are constrained by the large domain size and high Re that need to be simulated. When these simulations are preformed, turbine geometry is typically simplified resulting in flow structures near the rotor not being well resolved. In order to bypass these limitations, a quantitative flow visualization method was developed to take in situ measurements of the flow around wind turbines at the Field Laboratory for Optimized Wind Energy (FLOWE) in Lancaster, CA. The apparatus constructed was able to seed an approximately 9m x 9m x 5m volume in the wake of the turbine using artificial snow. Quantitative measurements were obtained by tracking the evolution of the artificial snow using a four camera setup. The methodology for calibrating and collecting data, as well as preliminary results detailing the flow around a 2kW vertical-axis wind turbine (VAWT), will be presented.

  7. Systems and Methods for Data Visualization Using Three-Dimensional Displays

    NASA Technical Reports Server (NTRS)

    Davidoff, Scott (Inventor); Djorgovski, Stanislav G. (Inventor); Estrada, Vicente (Inventor); Donalek, Ciro (Inventor)

    2017-01-01

    Data visualization systems and methods for generating 3D visualizations of a multidimensional data space are described. In one embodiment a 3D data visualization application directs a processing system to: load a set of multidimensional data points into a visualization table; create representations of a set of 3D objects corresponding to the set of data points; receive mappings of data dimensions to visualization attributes; determine the visualization attributes of the set of 3D objects based upon the selected mappings of data dimensions to 3D object attributes; update a visibility dimension in the visualization table for each of the plurality of 3D object to reflect the visibility of each 3D object based upon the selected mappings of data dimensions to visualization attributes; and interactively render 3D data visualizations of the 3D objects within the virtual space from viewpoints determined based upon received user input.

  8. Research on Visualization of Ground Laser Radar Data Based on Osg

    NASA Astrophysics Data System (ADS)

    Huang, H.; Hu, C.; Zhang, F.; Xue, H.

    2018-04-01

    Three-dimensional (3D) laser scanning is a new advanced technology integrating light, machine, electricity, and computer technologies. It can conduct 3D scanning to the whole shape and form of space objects with high precision. With this technology, you can directly collect the point cloud data of a ground object and create the structure of it for rendering. People use excellent 3D rendering engine to optimize and display the 3D model in order to meet the higher requirements of real time realism rendering and the complexity of the scene. OpenSceneGraph (OSG) is an open source 3D graphics engine. Compared with the current mainstream 3D rendering engine, OSG is practical, economical, and easy to expand. Therefore, OSG is widely used in the fields of virtual simulation, virtual reality, science and engineering visualization. In this paper, a dynamic and interactive ground LiDAR data visualization platform is constructed based on the OSG and the cross-platform C++ application development framework Qt. In view of the point cloud data of .txt format and the triangulation network data file of .obj format, the functions of 3D laser point cloud and triangulation network data display are realized. It is proved by experiments that the platform is of strong practical value as it is easy to operate and provides good interaction.

  9. Pollen structure visualization using high-resolution laboratory-based hard X-ray tomography.

    PubMed

    Li, Qiong; Gluch, Jürgen; Krüger, Peter; Gall, Martin; Neinhuis, Christoph; Zschech, Ehrenfried

    2016-10-14

    A laboratory-based X-ray microscope is used to investigate the 3D structure of unstained whole pollen grains. For the first time, high-resolution laboratory-based hard X-ray microscopy is applied to study pollen grains. Based on the efficient acquisition of statistically relevant information-rich images using Zernike phase contrast, both surface- and internal structures of pine pollen - including exine, intine and cellular structures - are clearly visualized. The specific volumes of these structures are calculated from the tomographic data. The systematic three-dimensional study of pollen grains provides morphological and structural information about taxonomic characters that are essential in palynology. Such studies have a direct impact on disciplines such as forestry, agriculture, horticulture, plant breeding and biodiversity. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Gravity influences top-down signals in visual processing.

    PubMed

    Cheron, Guy; Leroy, Axelle; Palmero-Soler, Ernesto; De Saedeleer, Caty; Bengoetxea, Ana; Cebolla, Ana-Maria; Vidal, Manuel; Dan, Bernard; Berthoz, Alain; McIntyre, Joseph

    2014-01-01

    Visual perception is not only based on incoming visual signals but also on information about a multimodal reference frame that incorporates vestibulo-proprioceptive input and motor signals. In addition, top-down modulation of visual processing has previously been demonstrated during cognitive operations including selective attention and working memory tasks. In the absence of a stable gravitational reference, the updating of salient stimuli becomes crucial for successful visuo-spatial behavior by humans in weightlessness. Here we found that visually-evoked potentials triggered by the image of a tunnel just prior to an impending 3D movement in a virtual navigation task were altered in weightlessness aboard the International Space Station, while those evoked by a classical 2D-checkerboard were not. Specifically, the analysis of event-related spectral perturbations and inter-trial phase coherency of these EEG signals recorded in the frontal and occipital areas showed that phase-locking of theta-alpha oscillations was suppressed in weightlessness, but only for the 3D tunnel image. Moreover, analysis of the phase of the coherency demonstrated the existence on Earth of a directional flux in the EEG signals from the frontal to the occipital areas mediating a top-down modulation during the presentation of the image of the 3D tunnel. In weightlessness, this fronto-occipital, top-down control was transformed into a diverging flux from the central areas toward the frontal and occipital areas. These results demonstrate that gravity-related sensory inputs modulate primary visual areas depending on the affordances of the visual scene.

  11. Application of Digital Diagnosis and Treatment Technique in Benign Mandibular Diseases.

    PubMed

    Ju, Rui; Zeng, Wei; Lian, Xiaotian; Chen, Gang; Yin, Huaqiang; Tang, Wei

    2018-05-01

    To explore the feasibility of preoperative planning for treatment of benign mandibular lesions (BML) using digital technologies such as three-dimensional (3D) reconstruction, measurement, visualization as well as image contrast and design of neural positioning protection template (NPPT) in combination with 3D printing technology in the BML diagnosis and treatment. The 3D models of BML and inferior alveolar nerves (IAN) of 10 BML patients were reconstructed based on their digital imaging and communications in medicine (DICOM) data using MIMICS16.0 software. The models were used to visualize lesions and nerve contrast measurement and guide design of personalized NPPT and osteotomy after operation modality was determined in order to achieve accurate, minimally invasive operation with shortened intraoperative time. Intraoperative NPPT application could accurately locate lesions and their scope and assist osteotomy. The measurement results were consistent with those of preoperative reconstruction and measurement. The BML were curetted completely without damage IAN. The 10 BML patients had no numbness and other discomforts in the lower lip and mandibular teeth after operation. The digital diagnosis and treatment technology is an effective method for functional treatment of BML patients and its application could achieve personalized, minimally invasive and precise treatment and save intraoperation time.

  12. Multi-energy method of digital radiography for imaging of biological objects

    NASA Astrophysics Data System (ADS)

    Ryzhikov, V. D.; Naydenov, S. V.; Opolonin, O. D.; Volkov, V. G.; Smith, C. F.

    2016-03-01

    This work has been dedicated to the search for a new possibility to use multi-energy digital radiography (MER) for medical applications. Our work has included both theoretical and experimental investigations of 2-energy (2E) and 3- energy (3D) radiography for imaging the structure of biological objects. Using special simulation methods and digital analysis based on the X-ray interaction energy dependence for each element of importance to medical applications in the X-ray range of energy up to 150 keV, we have implemented a quasi-linear approximation for the energy dependence of the X-ray linear mass absorption coefficient μm (E) that permits us to determine the intrinsic structure of the biological objects. Our measurements utilize multiple X-ray tube voltages (50, 100, and 150 kV) with Al and Cu filters of different thicknesses to achieve 3-energy X-ray examination of objects. By doing so, we are able to achieve significantly improved imaging quality of the structure of the subject biological objects. To reconstruct and visualize the final images, we use both two-dimensional (2D) and three-dimensional (3D) palettes of identification. The result is a 2E and/or 3E representation of the object with color coding of each pixel according to the data outputs. Following the experimental measurements and post-processing, we produce a 3D image of the biological object - in the case of our trials, fragments or parts of chicken and turkey.

  13. 3D T2-weighted and Gd-EOB-DTPA-enhanced 3D T1-weighted MR cholangiography for evaluation of biliary anatomy in living liver donors.

    PubMed

    Cai, Larry; Yeh, Benjamin M; Westphalen, Antonio C; Roberts, John; Wang, Zhen J

    2017-03-01

    To investigate whether the addition of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced 3D T1-weighted MR cholangiography (T1w-MRC) to 3D T2-weighted MRC (T2w-MRC) improves the confidence and diagnostic accuracy of biliary anatomy in living liver donors. Two abdominal radiologists retrospectively and independently reviewed pre-operative MR studies in 58 consecutive living liver donors. The second-order bile duct visualization on T1w- and T2w-MRC images was rated on a 4-point scale. The readers also independently recorded the biliary anatomy and their diagnostic confidence using (1) combined T1w- and T2w-MRC, and (2) T2w-MRC. In the 23 right lobe donors, the biliary anatomy at imaging and the imaging-predicted number of duct orifices at surgery were compared to intra-operative findings. T1w-MRC had a higher proportion of excellent visualization than T2w-MRC, 66% vs. 45% for reader 1 and 60% vs. 31% for reader 2. The median confidence score for biliary anatomy diagnosis was significantly higher with combined T1w- and T2w-MRC than T2w-MRC alone for both readers (Reader 1: 3 vs. 2, p < 0.001; Reader 2: 3 vs. 1, p < 0.001). Compared to intra-operative findings, the accuracy of imaging-predicted number of duct orifices using combined T1w-and T2w-MRC was significantly higher than that using T2w-MRC alone (p = 0.034 for reader 1, p = 0.0082 for reader 2). The addition of Gd-EOB-DTPA-enhanced 3D T1w-MRC to 3D T2w-MRC improves second-order bile duct visualization and increases the confidence in biliary anatomy diagnosis and the accuracy in the imaging-predicted number of duct orifices acquired during right lobe harvesting.

  14. Visualization of Documents and Concepts in Neuroinformatics with the 3D-SE Viewer

    PubMed Central

    Naud, Antoine; Usui, Shiro; Ueda, Naonori; Taniguchi, Tatsuki

    2007-01-01

    A new interactive visualization tool is proposed for mining text data from various fields of neuroscience. Applications to several text datasets are presented to demonstrate the capability of the proposed interactive tool to visualize complex relationships between pairs of lexical entities (with some semantic contents) such as terms, keywords, posters, or papers' abstracts. Implemented as a Java applet, this tool is based on the spherical embedding (SE) algorithm, which was designed for the visualization of bipartite graphs. Items such as words and documents are linked on the basis of occurrence relationships, which can be represented in a bipartite graph. These items are visualized by embedding the vertices of the bipartite graph on spheres in a three-dimensional (3-D) space. The main advantage of the proposed visualization tool is that 3-D layouts can convey more information than planar or linear displays of items or graphs. Different kinds of information extracted from texts, such as keywords, indexing terms, or topics are visualized, allowing interactive browsing of various fields of research featured by keywords, topics, or research teams. A typical use of the 3D-SE viewer is quick browsing of topics displayed on a sphere, then selecting one or several item(s) displays links to related terms on another sphere representing, e.g., documents or abstracts, and provides direct online access to the document source in a database, such as the Visiome Platform or the SfN Annual Meeting. Developed as a Java applet, it operates as a tool on top of existing resources. PMID:18974802

  15. Visualization of Documents and Concepts in Neuroinformatics with the 3D-SE Viewer.

    PubMed

    Naud, Antoine; Usui, Shiro; Ueda, Naonori; Taniguchi, Tatsuki

    2007-01-01

    A new interactive visualization tool is proposed for mining text data from various fields of neuroscience. Applications to several text datasets are presented to demonstrate the capability of the proposed interactive tool to visualize complex relationships between pairs of lexical entities (with some semantic contents) such as terms, keywords, posters, or papers' abstracts. Implemented as a Java applet, this tool is based on the spherical embedding (SE) algorithm, which was designed for the visualization of bipartite graphs. Items such as words and documents are linked on the basis of occurrence relationships, which can be represented in a bipartite graph. These items are visualized by embedding the vertices of the bipartite graph on spheres in a three-dimensional (3-D) space. The main advantage of the proposed visualization tool is that 3-D layouts can convey more information than planar or linear displays of items or graphs. Different kinds of information extracted from texts, such as keywords, indexing terms, or topics are visualized, allowing interactive browsing of various fields of research featured by keywords, topics, or research teams. A typical use of the 3D-SE viewer is quick browsing of topics displayed on a sphere, then selecting one or several item(s) displays links to related terms on another sphere representing, e.g., documents or abstracts, and provides direct online access to the document source in a database, such as the Visiome Platform or the SfN Annual Meeting. Developed as a Java applet, it operates as a tool on top of existing resources.

  16. Immersive Visual Data Analysis For Geoscience Using Commodity VR Hardware

    NASA Astrophysics Data System (ADS)

    Kreylos, O.; Kellogg, L. H.

    2017-12-01

    Immersive visualization using virtual reality (VR) display technology offers tremendous benefits for the visual analysis of complex three-dimensional data like those commonly obtained from geophysical and geological observations and models. Unlike "traditional" visualization, which has to project 3D data onto a 2D screen for display, VR can side-step this projection and display 3D data directly, in a pseudo-holographic (head-tracked stereoscopic) form, and does therefore not suffer the distortions of relative positions, sizes, distances, and angles that are inherent in 2D projection. As a result, researchers can apply their spatial reasoning skills to virtual data in the same way they can to real objects or environments. The UC Davis W.M. Keck Center for Active Visualization in the Earth Sciences (KeckCAVES, http://keckcaves.org) has been developing VR methods for data analysis since 2005, but the high cost of VR displays has been preventing large-scale deployment and adoption of KeckCAVES technology. The recent emergence of high-quality commodity VR, spearheaded by the Oculus Rift and HTC Vive, has fundamentally changed the field. With KeckCAVES' foundational VR operating system, Vrui, now running natively on the HTC Vive, all KeckCAVES visualization software, including 3D Visualizer, LiDAR Viewer, Crusta, Nanotech Construction Kit, and ProtoShop, are now available to small labs, single researchers, and even home users. LiDAR Viewer and Crusta have been used for rapid response to geologic events including earthquakes and landslides, to visualize the impacts of sealevel rise, to investigate reconstructed paleooceanographic masses, and for exploration of the surface of Mars. The Nanotech Construction Kit is being used to explore the phases of carbon in Earth's deep interior, while ProtoShop can be used to construct and investigate protein structures.

  17. Extensible 3D (X3D) Graphics for Visualizing Marine Mammal Reaction to Underwater Sound on the Southern California ASW Range (SOAR)

    DTIC Science & Technology

    2007-06-01

    file ARC- 20060811T130816.txt, where color is used to represent points in time (red being the earliest, transitioning to orange, yellow , then white...Administration (NOAA), using passive hydrophone arrays along the mid-Atlantic ridge to listen for underwater earthquakes and volcanoes , have found that a...appeared. The earliest data points were designated red, and later points were shades of orange and yellow , until the last points (relative to the

  18. Visualization in aerospace research with a large wall display system

    NASA Astrophysics Data System (ADS)

    Matsuo, Yuichi

    2002-05-01

    National Aerospace Laboratory of Japan has built a large- scale visualization system with a large wall-type display. The system has been operational since April 2001 and comprises a 4.6x1.5-meter (15x5-foot) rear projection screen with 3 BARCO 812 high-resolution CRT projectors. The reason we adopted the 3-gun CRT projectors is support for stereoscopic viewing, ease with color/luminosity matching and accuracy of edge-blending. The system is driven by a new SGI Onyx 3400 server of distributed shared-memory architecture with 32 CPUs, 64Gbytes memory, 1.5TBytes FC RAID disk and 6 IR3 graphics pipelines. Software is another important issue for us to make full use of the system. We have introduced some applications available in a multi- projector environment such as AVS/MPE, EnSight Gold and COVISE, and been developing some software tools that create volumetric images with using SGI graphics libraries. The system is mainly used for visualization fo computational fluid dynamics (CFD) simulation sin aerospace research. Visualized CFD results are of our help for designing an improved configuration of aerospace vehicles and analyzing their aerodynamic performances. These days we also use it for various collaborations among researchers.

  19. Ethene removal from a synthetic waste gas using a dry biobed.

    PubMed

    De Heyder, B; Overmeire, A; Van Langenhove, H; Verstraete, W

    1994-08-20

    A packed granular activated carbon (GAC) biobed, inoculated with the ethane-degrading strain Mycobacterium E3, was used to study ethene removal from a synthetic waste gas. Ethene, for which the dimensionless partition coefficient for an air-water system at 20 degrees C is about 7.6, was used as a model compound for poorly water soluble gaseous pollutants. In a first mode or operation, the GAC biobed was sprinkled intermittently and the waste gas influent was continuously pre-humidified, establishing relatively moist conditions (water content >40% to 45%). A volumetric ethene removal rate of 0.382 kg COD x m(-3) x d(-1) (0.112 kg ethene x m(-3) x d(-1)) was obtained for an influent concentration of 125 ppm, a superficial waste gas velocity of 3.6E-3 m x s(-1) and a pseudo residence time of 45 s. However, in the second mode of operation, omitting the pre-humidification of the waste gas influent and establishing a "dry" biobed (water content <40% to 45%), and thus obtaining better mass transfer to the biofilm, the ethene removal could be doubled for otherwise comparable operating parameters. Furthermore, under decreased wetting and for the given experimental conditions (influent concentration 125 to 816 ppm, waste gas superficial velocity 3.0E-3 m x s(-1), pseudo waste gas residence time 43 s), the ethene removal was not limited by mass transfer of ethene through the water layer covering the biofilm.

  20. A visual LISP program for voxelizing AutoCAD solid models

    NASA Astrophysics Data System (ADS)

    Marschallinger, Robert; Jandrisevits, Carmen; Zobl, Fritz

    2015-01-01

    AutoCAD solid models are increasingly recognized in geological and geotechnical 3D modeling. In order to bridge the currently existing gap between AutoCAD solid models and the grid modeling realm, a Visual LISP program is presented that converts AutoCAD solid models into voxel arrays. Acad2Vox voxelizer works on a 3D-model that is made up of arbitrary non-overlapping 3D-solids. After definition of the target voxel array geometry, 3D-solids are scanned at grid positions and properties are streamed to an ASCII output file. Acad2Vox has a novel voxelization strategy that combines a hierarchical reduction of sampling dimensionality with an innovative use of AutoCAD-specific methods for a fast and memory-saving operation. Acad2Vox provides georeferenced, voxelized analogs of 3D design data that can act as regions-of-interest in later geostatistical modeling and simulation. The Supplement includes sample geological solid models with instructions for practical work with Acad2Vox.

  1. J-2X, The Engine of the Future

    NASA Technical Reports Server (NTRS)

    Smith, Gail

    2009-01-01

    My project was two-fold, with both parts involving the J-2X Upper Stage engine (which will be used on both the Ares I and V). Mainly, I am responsible for using a program called Iris to create visual represen tations of the rocket engine's telemetry data. Also, my project includes the application of my newly acquired Pro Engineer skills in develo ping a 3D model of the engine's nozzle.

  2. The Virtual Insect Brain protocol: creating and comparing standardized neuroanatomy

    PubMed Central

    Jenett, Arnim; Schindelin, Johannes E; Heisenberg, Martin

    2006-01-01

    Background In the fly Drosophila melanogaster, new genetic, physiological, molecular and behavioral techniques for the functional analysis of the brain are rapidly accumulating. These diverse investigations on the function of the insect brain use gene expression patterns that can be visualized and provide the means for manipulating groups of neurons as a common ground. To take advantage of these patterns one needs to know their typical anatomy. Results This paper describes the Virtual Insect Brain (VIB) protocol, a script suite for the quantitative assessment, comparison, and presentation of neuroanatomical data. It is based on the 3D-reconstruction and visualization software Amira, version 3.x (Mercury Inc.) [1]. Besides its backbone, a standardization procedure which aligns individual 3D images (series of virtual sections obtained by confocal microscopy) to a common coordinate system and computes average intensities for each voxel (volume pixel) the VIB protocol provides an elaborate data management system for data administration. The VIB protocol facilitates direct comparison of gene expression patterns and describes their interindividual variability. It provides volumetry of brain regions and helps to characterize the phenotypes of brain structure mutants. Using the VIB protocol does not require any programming skills since all operations are carried out at an intuitively usable graphical user interface. Although the VIB protocol has been developed for the standardization of Drosophila neuroanatomy, the program structure can be used for the standardization of other 3D structures as well. Conclusion Standardizing brains and gene expression patterns is a new approach to biological shape and its variability. The VIB protocol provides a first set of tools supporting this endeavor in Drosophila. The script suite is freely available at [2] PMID:17196102

  3. 3D multimodal cardiac data reconstruction using angiography and computerized tomographic angiography registration.

    PubMed

    Moosavi Tayebi, Rohollah; Wirza, Rahmita; Sulaiman, Puteri S B; Dimon, Mohd Zamrin; Khalid, Fatimah; Al-Surmi, Aqeel; Mazaheri, Samaneh

    2015-04-22

    Computerized tomographic angiography (3D data representing the coronary arteries) and X-ray angiography (2D X-ray image sequences providing information about coronary arteries and their stenosis) are standard and popular assessment tools utilized for medical diagnosis of coronary artery diseases. At present, the results of both modalities are individually analyzed by specialists and it is difficult for them to mentally connect the details of these two techniques. The aim of this work is to assist medical diagnosis by providing specialists with the relationship between computerized tomographic angiography and X-ray angiography. In this study, coronary arteries from two modalities are registered in order to create a 3D reconstruction of the stenosis position. The proposed method starts with coronary artery segmentation and labeling for both modalities. Then, stenosis and relevant labeled artery in X-ray angiography image are marked by a specialist. Proper control points for the marked artery in both modalities are automatically detected and normalized. Then, a geometrical transformation function is computed using these control points. Finally, this function is utilized to register the marked artery from the X-ray angiography image on the computerized tomographic angiography and get the 3D position of the stenosis lesion. The result is a 3D informative model consisting of stenosis and coronary arteries' information from the X-ray angiography and computerized tomographic angiography modalities. The results of the proposed method for coronary artery segmentation, labeling and 3D reconstruction are evaluated and validated on the dataset containing both modalities. The advantage of this method is to aid specialists to determine a visual relationship between the correspondent coronary arteries from two modalities and also set up a connection between stenosis points from an X-ray angiography along with their 3D positions on the coronary arteries from computerized tomographic angiography. Moreover, another benefit of this work is that the medical acquisition standards remain unchanged, which means that no calibration in the acquisition devices is required. It can be applied on most computerized tomographic angiography and angiography devices.

  4. Visualization of oxygen transfer across the air-water interface using a fluorescence oxygen visualization method.

    PubMed

    Lee, Minhee

    2002-04-01

    Oxygen concentration fields in a water body were visualized by the fluorescence oxygen visualization (FOV) method. Pyrenebutyric acid (PBA) was used as a fluorescent indicator of oxygen, and an intensive charge coupled-device (ICCD) camera as an image detector. Sequential images (over 2000 images) of the oxygen concentration field around the surface water of the tank (1 x 1 x 0.75 m3) were produced during the 3 h experiment. From image processing, the accurate pathway of oxygen-rich, cold water at the water surface was also visualized. The amount of oxygen transferred through the air-water interface during the experiment was measured and the oxygen transfer coefficient (K(L)) was determined as 0.22 m/d, which was much higher than that is expected in molecular diffusion. Results suggest that vertical penetration of cold water was the main pathway of oxygen in the water body in the tank. The average velocity of cold water penetrating downward in water body was also measured from consecutive images and the value was 0.3-0.6 mm/s. The FOV method used in this research should have wide application in experimental fluid mechanics and can also provide a phenomenological description of oxygen transfer under physically realizable natural conditions in lakes and reservoirs.

  5. Interactive X-ray and proton therapy training and simulation.

    PubMed

    Hamza-Lup, Felix G; Farrar, Shane; Leon, Erik

    2015-10-01

    External beam X-ray therapy (XRT) and proton therapy (PT) are effective and widely accepted forms of treatment for many types of cancer. However, the procedures require extensive computerized planning. Current planning systems for both XRT and PT have insufficient visual aid to combine real patient data with the treatment device geometry to account for unforeseen collisions among system components and the patient. The 3D surface representation (S-rep) is a widely used scheme to create 3D models of physical objects. 3D S-reps have been successfully used in CAD/CAM and, in conjunction with texture mapping, in the modern gaming industry to customize avatars and improve the gaming realism and sense of presence. We are proposing a cost-effective method to extract patient-specific S-reps in real time and combine them with the treatment system geometry to provide a comprehensive simulation of the XRT/PT treatment room. The X3D standard is used to implement and deploy the simulator on the web, enabling its use not only for remote specialists' collaboration, simulation, and training, but also for patient education. An objective assessment of the accuracy of the S-reps obtained proves the potential of the simulator for clinical use.

  6. Automatic Localization of Vertebral Levels in X-Ray Fluoroscopy Using 3D-2D Registration: A Tool to Reduce Wrong-Site Surgery

    PubMed Central

    Otake, Y.; Schafer, S.; Stayman, J. W.; Zbijewski, W.; Kleinszig, G.; Graumann, R.; Khanna, A. J.; Siewerdsen, J. H.

    2012-01-01

    Surgical targeting of the incorrect vertebral level (“wrong-level” surgery) is among the more common wrong-site surgical errors, attributed primarily to a lack of uniquely identifiable radiographic landmarks in the mid-thoracic spine. Conventional localization method involves manual counting of vertebral bodies under fluoroscopy, is prone to human error, and carries additional time and dose. We propose an image registration and visualization system (referred to as LevelCheck), for decision support in spine surgery by automatically labeling vertebral levels in fluoroscopy using a GPU-accelerated, intensity-based 3D-2D (viz., CT-to-fluoroscopy) registration. A gradient information (GI) similarity metric and CMA-ES optimizer were chosen due to their robustness and inherent suitability for parallelization. Simulation studies involved 10 patient CT datasets from which 50,000 simulated fluoroscopic images were generated from C-arm poses selected to approximate C-arm operator and positioning variability. Physical experiments used an anthropomorphic chest phantom imaged under real fluoroscopy. The registration accuracy was evaluated as the mean projection distance (mPD) between the estimated and true center of vertebral levels. Trials were defined as successful if the estimated position was within the projection of the vertebral body (viz., mPD < 5mm). Simulation studies showed a success rate of 99.998% (1 failure in 50,000 trials) and computation time of 4.7 sec on a midrange GPU. Analysis of failure modes identified cases of false local optima in the search space arising from longitudinal periodicity in vertebral structures. Physical experiments demonstrated robustness of the algorithm against quantum noise and x-ray scatter. The ability to automatically localize target anatomy in fluoroscopy in near-real-time could be valuable in reducing the occurrence of wrong-site surgery while helping to reduce radiation exposure. The method is applicable beyond the specific case of vertebral labeling, since any structure defined in pre-operative (or intra-operative) CT or cone-beam CT can be automatically registered to the fluoroscopic scene. PMID:22864366

  7. Synchrotron x-ray imaging of pulmonary alveoli in respiration in live intact mice

    NASA Astrophysics Data System (ADS)

    Chang, Soeun; Kwon, Namseop; Kim, Jinkyung; Kohmura, Yoshiki; Ishikawa, Tetsuya; Rhee, Chin Kook; Je, Jung Ho; Tsuda, Akira

    2015-03-01

    Despite nearly a half century of studies, it has not been fully understood how pulmonary alveoli, the elementary gas exchange units in mammalian lungs, inflate and deflate during respiration. Understanding alveolar dynamics is crucial for treating patients with pulmonary diseases. In-vivo, real-time visualization of the alveoli during respiration has been hampered by active lung movement. Previous studies have been therefore limited to alveoli at lung apices or subpleural alveoli under open thorax conditions. Here we report direct and real-time visualization of alveoli of live intact mice during respiration using tracking X-ray microscopy. Our studies, for the first time, determine the alveolar size of normal mice in respiration without positive end expiratory pressure as 58 +/- 14 (mean +/- s.d.) μm on average, accurately measured in the lung bases as well as the apices. Individual alveoli of normal lungs clearly show heterogeneous inflation from zero to ~25% (6.7 +/- 4.7% (mean +/- s.d.)) in size. The degree of inflation is higher in the lung bases (8.7 +/- 4.3% (mean +/- s.d.)) than in the apices (5.7 +/- 3.2% (mean +/- s.d.)). The fraction of the total tidal volume allocated for alveolar inflation is 34 +/- 3.8% (mean +/- s.e.m). This study contributes to the better understanding of alveolar dynamics and helps to develop potential treatment options for pulmonary diseases.

  8. Visual disability, visual function, and myopia among rural chinese secondary school children: the Xichang Pediatric Refractive Error Study (X-PRES)--report 1.

    PubMed

    Congdon, Nathan; Wang, Yunfei; Song, Yue; Choi, Kai; Zhang, Mingzhi; Zhou, Zhongxia; Xie, Zhenling; Li, Liping; Liu, Xueyu; Sharma, Abhishek; Wu, Bin; Lam, Dennis S C

    2008-07-01

    To evaluate visual acuity, visual function, and prevalence of refractive error among Chinese secondary-school children in a cross-sectional school-based study. Uncorrected, presenting, and best corrected visual acuity, cycloplegic autorefraction with refinement, and self-reported visual function were assessed in a random, cluster sample of rural secondary school students in Xichang, China. Among the 1892 subjects (97.3% of the consenting children, 84.7% of the total sample), mean age was 14.7 +/- 0.8 years, 51.2% were female, and 26.4% were wearing glasses. The proportion of children with uncorrected, presenting, and corrected visual disability (< or = 6/12 in the better eye) was 41.2%, 19.3%, and 0.5%, respectively. Myopia < -0.5, < -2.0, and < -6.0 D in both eyes was present in 62.3%, 31.1%, and 1.9% of the subjects, respectively. Among the children with visual disability when tested without correction, 98.7% was due to refractive error, while only 53.8% (414/770) of these children had appropriate correction. The girls had significantly (P < 0.001) more presenting visual disability and myopia < -2.0 D than did the boys. More myopic refractive error was associated with worse self-reported visual function (ANOVA trend test, P < 0.001). Visual disability in this population was common, highly correctable, and frequently uncorrected. The impact of refractive error on self-reported visual function was significant. Strategies and studies to understand and remove barriers to spectacle wear are needed.

  9. Shutdown Dose Rate Analysis for the long-pulse D-D Operation Phase in KSTAR

    NASA Astrophysics Data System (ADS)

    Park, Jin Hun; Han, Jung-Hoon; Kim, D. H.; Joo, K. S.; Hwang, Y. S.

    2017-09-01

    KSTAR is a medium size fully superconducting tokamak. The deuterium-deuterium (D-D) reaction in the KSTAR tokamak generates neutrons with a peak yield of 3.5x1016 per second through a pulse operation of 100 seconds. The effect of neutron generation from full D-D high power KSTAR operation mode to the machine, such as activation, shutdown dose rate, and nuclear heating, are estimated for an assurance of safety during operation, maintenance, and machine upgrade. The nuclear heating of the in-vessel components, and neutron activation of the surrounding materials have been investigated. The dose rates during operation and after shutdown of KSTAR have been calculated by a 3D CAD model of KSTAR with the Monte Carlo code MCNP5 (neutron flux and decay photon), the inventory code FISPACT (activation and decay photon) and the FENDL 2.1 nuclear data library.

  10. Stereoscopic augmented reality for laparoscopic surgery.

    PubMed

    Kang, Xin; Azizian, Mahdi; Wilson, Emmanuel; Wu, Kyle; Martin, Aaron D; Kane, Timothy D; Peters, Craig A; Cleary, Kevin; Shekhar, Raj

    2014-07-01

    Conventional laparoscopes provide a flat representation of the three-dimensional (3D) operating field and are incapable of visualizing internal structures located beneath visible organ surfaces. Computed tomography (CT) and magnetic resonance (MR) images are difficult to fuse in real time with laparoscopic views due to the deformable nature of soft-tissue organs. Utilizing emerging camera technology, we have developed a real-time stereoscopic augmented-reality (AR) system for laparoscopic surgery by merging live laparoscopic ultrasound (LUS) with stereoscopic video. The system creates two new visual cues: (1) perception of true depth with improved understanding of 3D spatial relationships among anatomical structures, and (2) visualization of critical internal structures along with a more comprehensive visualization of the operating field. The stereoscopic AR system has been designed for near-term clinical translation with seamless integration into the existing surgical workflow. It is composed of a stereoscopic vision system, a LUS system, and an optical tracker. Specialized software processes streams of imaging data from the tracked devices and registers those in real time. The resulting two ultrasound-augmented video streams (one for the left and one for the right eye) give a live stereoscopic AR view of the operating field. The team conducted a series of stereoscopic AR interrogations of the liver, gallbladder, biliary tree, and kidneys in two swine. The preclinical studies demonstrated the feasibility of the stereoscopic AR system during in vivo procedures. Major internal structures could be easily identified. The system exhibited unobservable latency with acceptable image-to-video registration accuracy. We presented the first in vivo use of a complete system with stereoscopic AR visualization capability. This new capability introduces new visual cues and enhances visualization of the surgical anatomy. The system shows promise to improve the precision and expand the capacity of minimally invasive laparoscopic surgeries.

  11. High-resolution Episcopic Microscopy (HREM) - Simple and Robust Protocols for Processing and Visualizing Organic Materials

    PubMed Central

    Geyer, Stefan H.; Maurer-Gesek, Barbara; Reissig, Lukas F.; Weninger, Wolfgang J.

    2017-01-01

    We provide simple protocols for generating digital volume data with the high-resolution episcopic microscopy (HREM) method. HREM is capable of imaging organic materials with volumes up to 5 x 5 x 7 mm3 in typical numeric resolutions between 1 x 1 x 1 and 5 x 5 x 5 µm3. Specimens are embedded in methacrylate resin and sectioned on a microtome. After each section an image of the block surface is captured with a digital video camera that sits on the phototube connected to the compound microscope head. The optical axis passes through a green fluorescent protein (GFP) filter cube and is aligned with a position, at which the bock holder arm comes to rest after each section. In this way, a series of inherently aligned digital images, displaying subsequent block surfaces are produced. Loading such an image series in three-dimensional (3D) visualization software facilitates the immediate conversion to digital volume data, which permit virtual sectioning in various orthogonal and oblique planes and the creation of volume and surface rendered computer models. We present three simple, tissue specific protocols for processing various groups of organic specimens, including mouse, chick, quail, frog and zebra fish embryos, human biopsy material, uncoated paper and skin replacement material. PMID:28715372

  12. High-resolution Episcopic Microscopy (HREM) - Simple and Robust Protocols for Processing and Visualizing Organic Materials.

    PubMed

    Geyer, Stefan H; Maurer-Gesek, Barbara; Reissig, Lukas F; Weninger, Wolfgang J

    2017-07-07

    We provide simple protocols for generating digital volume data with the high-resolution episcopic microscopy (HREM) method. HREM is capable of imaging organic materials with volumes up to 5 x 5 x 7 mm 3 in typical numeric resolutions between 1 x 1 x 1 and 5 x 5 x 5 µm 3 . Specimens are embedded in methacrylate resin and sectioned on a microtome. After each section an image of the block surface is captured with a digital video camera that sits on the phototube connected to the compound microscope head. The optical axis passes through a green fluorescent protein (GFP) filter cube and is aligned with a position, at which the bock holder arm comes to rest after each section. In this way, a series of inherently aligned digital images, displaying subsequent block surfaces are produced. Loading such an image series in three-dimensional (3D) visualization software facilitates the immediate conversion to digital volume data, which permit virtual sectioning in various orthogonal and oblique planes and the creation of volume and surface rendered computer models. We present three simple, tissue specific protocols for processing various groups of organic specimens, including mouse, chick, quail, frog and zebra fish embryos, human biopsy material, uncoated paper and skin replacement material.

  13. Nerves of Steel: a Low-Cost Method for 3D Printing the Cranial Nerves.

    PubMed

    Javan, Ramin; Davidson, Duncan; Javan, Afshin

    2017-10-01

    Steady-state free precession (SSFP) magnetic resonance imaging (MRI) can demonstrate details down to the cranial nerve (CN) level. High-resolution three-dimensional (3D) visualization can now quickly be performed at the workstation. However, we are still limited by visualization on flat screens. The emerging technologies in rapid prototyping or 3D printing overcome this limitation. It comprises a variety of automated manufacturing techniques, which use virtual 3D data sets to fabricate solid forms in a layer-by-layer technique. The complex neuroanatomy of the CNs may be better understood and depicted by the use of highly customizable advanced 3D printed models. In this technical note, after manually perfecting the segmentation of each CN and brain stem on each SSFP-MRI image, initial 3D reconstruction was performed. The bony skull base was also reconstructed from computed tomography (CT) data. Autodesk 3D Studio Max, available through freeware student/educator license, was used to three-dimensionally trace the 3D reconstructed CNs in order to create smooth graphically designed CNs and to assure proper fitting of the CNs into their respective neural foramina and fissures. This model was then 3D printed with polyamide through a commercial online service. Two different methods are discussed for the key segmentation and 3D reconstruction steps, by either using professional commercial software, i.e., Materialise Mimics, or utilizing a combination of the widely available software Adobe Photoshop, as well as a freeware software, OsiriX Lite.

  14. Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography

    PubMed Central

    Carrasco-Zevallos, O. M.; Keller, B.; Viehland, C.; Shen, L.; Waterman, G.; Todorich, B.; Shieh, C.; Hahn, P.; Farsiu, S.; Kuo, A. N.; Toth, C. A.; Izatt, J. A.

    2016-01-01

    Minimally-invasive microsurgery has resulted in improved outcomes for patients. However, operating through a microscope limits depth perception and fixes the visual perspective, which result in a steep learning curve to achieve microsurgical proficiency. We introduce a surgical imaging system employing four-dimensional (live volumetric imaging through time) microscope-integrated optical coherence tomography (4D MIOCT) capable of imaging at up to 10 volumes per second to visualize human microsurgery. A custom stereoscopic heads-up display provides real-time interactive volumetric feedback to the surgeon. We report that 4D MIOCT enhanced suturing accuracy and control of instrument positioning in mock surgical trials involving 17 ophthalmic surgeons. Additionally, 4D MIOCT imaging was performed in 48 human eye surgeries and was demonstrated to successfully visualize the pathology of interest in concordance with preoperative diagnosis in 93% of retinal surgeries and the surgical site of interest in 100% of anterior segment surgeries. In vivo 4D MIOCT imaging revealed sub-surface pathologic structures and instrument-induced lesions that were invisible through the operating microscope during standard surgical maneuvers. In select cases, 4D MIOCT guidance was necessary to resolve such lesions and prevent post-operative complications. Our novel surgical visualization platform achieves surgeon-interactive 4D visualization of live surgery which could expand the surgeon’s capabilities. PMID:27538478

  15. Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Carrasco-Zevallos, O. M.; Keller, B.; Viehland, C.; Shen, L.; Waterman, G.; Todorich, B.; Shieh, C.; Hahn, P.; Farsiu, S.; Kuo, A. N.; Toth, C. A.; Izatt, J. A.

    2016-08-01

    Minimally-invasive microsurgery has resulted in improved outcomes for patients. However, operating through a microscope limits depth perception and fixes the visual perspective, which result in a steep learning curve to achieve microsurgical proficiency. We introduce a surgical imaging system employing four-dimensional (live volumetric imaging through time) microscope-integrated optical coherence tomography (4D MIOCT) capable of imaging at up to 10 volumes per second to visualize human microsurgery. A custom stereoscopic heads-up display provides real-time interactive volumetric feedback to the surgeon. We report that 4D MIOCT enhanced suturing accuracy and control of instrument positioning in mock surgical trials involving 17 ophthalmic surgeons. Additionally, 4D MIOCT imaging was performed in 48 human eye surgeries and was demonstrated to successfully visualize the pathology of interest in concordance with preoperative diagnosis in 93% of retinal surgeries and the surgical site of interest in 100% of anterior segment surgeries. In vivo 4D MIOCT imaging revealed sub-surface pathologic structures and instrument-induced lesions that were invisible through the operating microscope during standard surgical maneuvers. In select cases, 4D MIOCT guidance was necessary to resolve such lesions and prevent post-operative complications. Our novel surgical visualization platform achieves surgeon-interactive 4D visualization of live surgery which could expand the surgeon’s capabilities.

  16. Intraoperative visualization and assessment of electromagnetic tracking error

    NASA Astrophysics Data System (ADS)

    Harish, Vinyas; Ungi, Tamas; Lasso, Andras; MacDonald, Andrew; Nanji, Sulaiman; Fichtinger, Gabor

    2015-03-01

    Electromagnetic tracking allows for increased flexibility in designing image-guided interventions, however it is well understood that electromagnetic tracking is prone to error. Visualization and assessment of the tracking error should take place in the operating room with minimal interference with the clinical procedure. The goal was to achieve this ideal in an open-source software implementation in a plug and play manner, without requiring programming from the user. We use optical tracking as a ground truth. An electromagnetic sensor and optical markers are mounted onto a stylus device, pivot calibrated for both trackers. Electromagnetic tracking error is defined as difference of tool tip position between electromagnetic and optical readings. Multiple measurements are interpolated into the thin-plate B-spline transform visualized in real time using 3D Slicer. All tracked devices are used in a plug and play manner through the open-source SlicerIGT and PLUS extensions of the 3D Slicer platform. Tracking error was measured multiple times to assess reproducibility of the method, both with and without placing ferromagnetic objects in the workspace. Results from exhaustive grid sampling and freehand sampling were similar, indicating that a quick freehand sampling is sufficient to detect unexpected or excessive field distortion in the operating room. The software is available as a plug-in for the 3D Slicer platforms. Results demonstrate potential for visualizing electromagnetic tracking error in real time for intraoperative environments in feasibility clinical trials in image-guided interventions.

  17. Evaluation of an Innovative Digital Assessment Tool in Dental Anatomy.

    PubMed

    Lam, Matt T; Kwon, So Ran; Qian, Fang; Denehy, Gerald E

    2015-05-01

    The E4D Compare software is an innovative tool that provides immediate feedback to students' projects and competencies. It should provide consistent scores even when different scanners are used which may have inherent subtle differences in calibration. This study aimed to evaluate potential discrepancies in evaluation using the E4D Compare software based on four different NEVO scanners in dental anatomy projects. Additionally, correlation between digital and visual scores was evaluated. Thirty-five projects of maxillary left central incisors were evaluated. Among these, thirty wax-ups were performed by four operators and five consisted of standard dentoform teeth. Five scores were obtained for each project: one from an instructor that visually graded the project and from four different NEVO scanners. A faculty involved in teaching the dental anatomy course blindly scored the 35 projects. One operator scanned all projects to four NEVO scanners (D4D Technologies, Richardson, TX, USA). The images were aligned to the gold standard, and tolerance set at 0.3 mm to generate a score. The score reflected percentage match between the project and the gold standard. One-way ANOVA with repeated measures was used to determine whether there was a significant difference in scores among the four NEVO scanners. Paired-sample t-test was used to detect any difference between visual scores and the average scores of the four NEVO scanners. Pearson's correlation test was used to assess the relationship between visual and average scores of NEVO scanners. There was no significant difference in mean scores among four different NEVO scanners [F(3, 102) = 2.27, p = 0.0852 one-way ANOVA with repeated measures]. Moreover, the data provided strong evidence that a significant difference existed between visual and digital scores (p = 0.0217; a paired - sample t-test). Mean visual scores were significantly lower than digital scores (72.4 vs 75.1). Pearson's correlation coefficient of 0.85 indicated a strong correlation between visual and digital scores (p < 0.0001). The E4D Compare software provides consistent scores even when different scanners are used and correlates well with visual scores. The use of innovative digital assessment tools in dental education is promising with the E4D Compare software correlating well with visual scores and providing consistent scores even when different scanners are used.

  18. 3D imaging of a rice pollen grain using transmission X-ray microscopy.

    PubMed

    Wang, Shengxiang; Wang, Dajiang; Wu, Qiao; Gao, Kun; Wang, Zhili; Wu, Ziyu

    2015-07-01

    For the first time, the three-dimensional (3D) ultrastructure of an intact rice pollen cell has been obtained using a full-field transmission hard X-ray microscope operated in Zernike phase contrast mode. After reconstruction and segmentation from a series of projection images, complete 3D structural information of a 35 µm rice pollen grain is presented at a resolution of ∼100 nm. The reconstruction allows a clear differentiation of various subcellular structures within the rice pollen grain, including aperture, lipid body, mitochondrion, nucleus and vacuole. Furthermore, quantitative information was obtained about the distribution of cytoplasmic organelles and the volume percentage of each kind of organelle. These results demonstrate that transmission X-ray microscopy can be quite powerful for non-destructive investigation of 3D structures of whole eukaryotic cells.

  19. Accuracy and efficiency of computer-aided anatomical analysis using 3D visualization software based on semi-automated and automated segmentations.

    PubMed

    An, Gao; Hong, Li; Zhou, Xiao-Bing; Yang, Qiong; Li, Mei-Qing; Tang, Xiang-Yang

    2017-03-01

    We investigated and compared the functionality of two 3D visualization software provided by a CT vendor and a third-party vendor, respectively. Using surgical anatomical measurement as baseline, we evaluated the accuracy of 3D visualization and verified their utility in computer-aided anatomical analysis. The study cohort consisted of 50 adult cadavers fixed with the classical formaldehyde method. The computer-aided anatomical analysis was based on CT images (in DICOM format) acquired by helical scan with contrast enhancement, using a CT vendor provided 3D visualization workstation (Syngo) and a third-party 3D visualization software (Mimics) that was installed on a PC. Automated and semi-automated segmentations were utilized in the 3D visualization workstation and software, respectively. The functionality and efficiency of automated and semi-automated segmentation methods were compared. Using surgical anatomical measurement as a baseline, the accuracy of 3D visualization based on automated and semi-automated segmentations was quantitatively compared. In semi-automated segmentation, the Mimics 3D visualization software outperformed the Syngo 3D visualization workstation. No significant difference was observed in anatomical data measurement by the Syngo 3D visualization workstation and the Mimics 3D visualization software (P>0.05). Both the Syngo 3D visualization workstation provided by a CT vendor and the Mimics 3D visualization software by a third-party vendor possessed the needed functionality, efficiency and accuracy for computer-aided anatomical analysis. Copyright © 2016 Elsevier GmbH. All rights reserved.

  20. Stereotaxic Irradiation-Procedure of Brain Tumors and Pituitary Adenomas by Means of Radio-Isotopes and its Results

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mundinger, F.; Riechert, T.

    1962-01-01

    The techniques, results, and complications of stereotactic implantation of P/sup 32/, Co/sup 60/, Ta/sup 182/, Ir/sup 192/, and Au/sup 198/ in the brain of 196 patients for radiotherapy of intracranial tumors are described. A stereotactic instrument is described and illustrated which permits implantation of the radioisotopes to within 0.5 mm of the desired site. There was a clear relation between the length of survival and the kind of radioisotope applied, localization of the tumor, and amount of the tumor dosage. With glioblastomas, for instance, longest survival was noted in those with frontal localization, following Co/sup 60/ irradiation, and an averagemore » tumor dosage of 10000 to 13000 r showed best results. Similar results, with even longer survival periods, were achieved in other dedifferentiated gliomas, in which the combination of intraoperative Ta/sup 182/ or Ir/sup 192/ implantation with a postoperative interstitial Co/sup 60/ irradiation achieved the best results, in comparison with a combination of operation and x-ray therapy. The survival rate, which is nearly twice as high as in x-ray treatment, shows a significant relation to the average tumor dosage and tumor localization. The period of treatment was also shortened by 65-75% compared to the time required for fractionated x-ray therapy. In 68% of the stereotaxic hypophysis operations, according to the size of the tumor, a total activity of 25 to 55 mc of a macromolecular suspension of Au/sup 198/ was implanted which was adsorbed on small graphite particles (50 to 60 mu ). In the other cases small seeds of P/sup 32/ were placed in the tumor. The long-term results show that visual acuity had improved significantly following secondary stereotaxic irradiation, or remained unaltered without change, in comparison to those patients that had been treated by operation only. On the other hand, the percentage of unimproved and deteriorated cases is much higher in the operated group. The operative mortality with primary stereotaxic punctures was nil, whereas surgical operative mortality totaled 19%. The survival rates of 90.4% of the patients with secondary stereotaxic irradiation and 76.1% with primary stereotaxic irradiation, in compari-son with only 62% of patients with operation only, prove significantly that effectively implanted interstitial irradiation can prolong life. Among operative complications, damage to the neighboring structures was not caused by stereotaxic puncture, but was caused secondarily by radiation, above all by gamma radiation. In six of the patients, therefore, an open decompression operation was necessary. There were some general transitory reactions in the first days, especially headache and cerebrospinal fluid pressure increase among recurrent and long-term complications, in 11.5%, visual acuity grew worse and the visual field was narrowed after 0.3 to 3 yr. It was concluded that primary, and especially secondary stereotaxic irradiation of hypophysis adenomas is clearly superior to surgical operation as concerns operative mortality as well as survival rate and rate of recurrence. The rate of improvement of visual acuity was 26 to 44% higher and that of the visual field 17 to 29% higher than following surgical operation only. However, one problem not yet solved satisfactorily is the long-term radiation damage of the chiasma and optic nerve. Perhaps filling the basal cisterns with x-ray contrast medium by means of the target needle, before the placing of the isotopes, may be of help in preventing this. (BBB)« less

  1. Targeted endomyocardial injections of therapeutic cells using x-ray fused with MRI guidance

    NASA Astrophysics Data System (ADS)

    Gutiérrez, Luis F.; de Silva, Ranil; McVeigh, Elliot R.; Ozturk, Cengizhan; Lederman, Robert J.

    2006-03-01

    The utility of X-ray fused with MRI (XFM) using external fiducial markers to perform targeted endomyocardial injections in infarcted hearts of swine was tested. Endomyocardial injections of feridex-labeled mesenchymal stromal cells (Fe-MSC) were performed in the previously infarcted hearts of 12 Yucatan miniswine (33-67 kg). Animals had pre-injection cardiac MRI, XFM-guided endomyocardial injection of Fe-MSC suspension spiked with tissue dye, and post-injection MRI. 24 hours later, after euthanasia, the hearts were excised, sliced and stained with TTC. During the injection procedure, operators were provided with 3D surfaces of endocardium, epicardium, myocardial wall thickness and infarct registered with live XF images to facilitate device navigation and choice of injection location. 130 injections were performed in hearts where diastolic wall thickness ranged from 2.6 to 17.7 mm. Visual inspection of the pattern of dye staining on TTC stained heart slices correlated (r=0.98) with XFM-derived injection locations mapped onto delayed hyperenhancement MRI and the susceptibility artifacts seen on the post-injection T2*-weighted gradient echo MRI. The in vivo target registration error was 3.17+/-2.61 mm (n=64) and 75% of injections were within 4 mm of the predicted location. 3D to 2D registration of XF and MR images using external fiducial markers enables accurate targeted endomyocardial injection in a swine model of myocardial infarction. The present data suggest that the safety and efficacy of this approach for performing targeted endomyocardial delivery should be evaluated further clinically.

  2. Image segmentation and 3D visualization for MRI mammography

    NASA Astrophysics Data System (ADS)

    Li, Lihua; Chu, Yong; Salem, Angela F.; Clark, Robert A.

    2002-05-01

    MRI mammography has a number of advantages, including the tomographic, and therefore three-dimensional (3-D) nature, of the images. It allows the application of MRI mammography to breasts with dense tissue, post operative scarring, and silicon implants. However, due to the vast quantity of images and subtlety of difference in MR sequence, there is a need for reliable computer diagnosis to reduce the radiologist's workload. The purpose of this work was to develop automatic breast/tissue segmentation and visualization algorithms to aid physicians in detecting and observing abnormalities in breast. Two segmentation algorithms were developed: one for breast segmentation, the other for glandular tissue segmentation. In breast segmentation, the MRI image is first segmented using an adaptive growing clustering method. Two tracing algorithms were then developed to refine the breast air and chest wall boundaries of breast. The glandular tissue segmentation was performed using an adaptive thresholding method, in which the threshold value was spatially adaptive using a sliding window. The 3D visualization of the segmented 2D slices of MRI mammography was implemented under IDL environment. The breast and glandular tissue rendering, slicing and animation were displayed.

  3. Intensity-based 2D 3D registration for lead localization in robot guided deep brain stimulation

    NASA Astrophysics Data System (ADS)

    Hunsche, Stefan; Sauner, Dieter; El Majdoub, Faycal; Neudorfer, Clemens; Poggenborg, Jörg; Goßmann, Axel; Maarouf, Mohammad

    2017-03-01

    Intraoperative assessment of lead localization has become a standard procedure during deep brain stimulation surgery in many centers, allowing immediate verification of targeting accuracy and, if necessary, adjustment of the trajectory. The most suitable imaging modality to determine lead positioning, however, remains controversially discussed. Current approaches entail the implementation of computed tomography and magnetic resonance imaging. In the present study, we adopted the technique of intensity-based 2D 3D registration that is commonly employed in stereotactic radiotherapy and spinal surgery. For this purpose, intraoperatively acquired 2D x-ray images were fused with preoperative 3D computed tomography (CT) data to verify lead placement during stereotactic robot assisted surgery. Accuracy of lead localization determined from 2D 3D registration was compared to conventional 3D 3D registration in a subsequent patient study. The mean Euclidian distance of lead coordinates estimated from intensity-based 2D 3D registration versus flat-panel detector CT 3D 3D registration was 0.7 mm  ±  0.2 mm. Maximum values of these distances amounted to 1.2 mm. To further investigate 2D 3D registration a simulation study was conducted, challenging two observers to visually assess artificially generated 2D 3D registration errors. 95% of deviation simulations, which were visually assessed as sufficient, had a registration error below 0.7 mm. In conclusion, 2D 3D intensity-based registration revealed high accuracy and reliability during robot guided stereotactic neurosurgery and holds great potential as a low dose, cost effective means for intraoperative lead localization.

  4. [Visual outcomes 5 years after small incision lenticule extraction (SMILE), surgery on spherocylindrical myopia eyes, from 616 eyes].

    PubMed

    Burazovitch, J; Ferguene, H; Naguszewski, D

    2018-05-15

    Determine if the visual criteria of the technique of surgery refractive by Femtosecond Laser-assisted duckweed Extraction - Small Lenticule Extraction (FLEx-Smile ® ), realized in the laser femtosecond VisuMax ® (Carl Zeiss Meditec, Jena, Germany), are stable, secure, effective and predictable in the long term, to the nearsighted and astigmatic. Retrospective study, monocentric with data collected between March 2012 and March 2017. The study included 616 eyes of 309 nearsighted and astigmatic patients (spherical equivalent from 1 to 11 D). They were followed in postoperative immediate (D+1), in 3 months, in 1 year and in 5 years. The taken measures include the refraction, the uncorrected visual acuteness (UVAC) and the best visual corrected acuteness (BVAC). The criteria of evaluation were based on the BVAC, the refractive stability, the index of security (IS: MAVC to preoperative D+1/BVAC before operation) and the predictability (percentage of eyes in±1 D of SE target). UVAC was better 5th year than after the intervention (P=0.001) and 88% of the operated eyes had an UVAC in 8/10 (logMAR=0.1). For the stability refractive, the patients became nearsighted between the intervention and 5th year (P=0.001), with a regression of 0.240 D. The indication of safety was better 5th year than the day after the intervention (P=0.001), 92% of eyes operated in 5 years were 0.5 D of SE target and 77% of eyes had lost no line. SMILE is a good technique of surgery refractive stable, secure, effective and predictable on the long term. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  5. X-ray Fluorescence Core Scanning of Oman Drilling Project Holes BT1B and GT3A Cores on D/V CHIKYU

    NASA Astrophysics Data System (ADS)

    Johnson, K. T. M.; Kelemen, P. B.; Michibayashi, K.; Greenberger, R. N.; Koepke, J.; Beinlich, A.; Morishita, T.; Jesus, A. P. M.; Lefay, R.

    2017-12-01

    The JEOL JSX-3600CA1 energy dispersive X-ray fluorescence core logger (XRF-CL) on the D/V Chikyu provides quantitative element concentrations of scanned cores. Scans of selected intervals are made on an x-y grid with point spacing of 5 mm. Element concentrations for Si, Al, Ti, Ca, Mg, Mn, Fe, Na, K, Cr, Ni, S and Zn are collected for each point on the grid. Accuracy of element concentrations provided by the instrument software is improved by applying empirical correction algorithms. Element concentrations were collected for 9,289 points from twenty-seven core intervals in Hole BT1B (basal thrust) and for 6,389 points from forty core intervals in Hole GT3A (sheeted dike-gabbro transition) of the Oman Drilling Project on the D/V Chikyu XRF-CL during Leg 2 of the Oman Drilling Project in August-September, 2017. The geochemical data are used for evaluating downhole compositional details associated with lithological changes, unit contacts and mineralogical variations and are particularly informative when plotted as concentration contour maps or downhole concentration diagrams. On Leg 2 additional core scans were made with X-ray Computed Tomography (X-ray CT) and infrared images from the visible-shortwave infrared imaging spectroscopy (IR) systems on board. XRF-CL, X-ray CT and IR imaging plots used together provide detailed information on rock compositions, textures and mineralogy that assist naked eye visual observations. Examples of some uses of XRF-CL geochemical maps and downhole data are shown. XRF-CL and IR scans of listvenite clearly show zones of magnesite, dolomite and the Cr-rich mica, fuchsite that are subdued in visual observation, and these scans can be used to calculate variations in proportions of these minerals in Hole BT1B cores. In Hole GT3A XRF-CL data can be used to distinguish compositional changes in different generations of sheeted dikes and gabbros and when combined with visual observations of intrusive relationships the detailed geochemical information can be used to infer temporal changes in parental magma compositions. Secondary sulfide mineralization and epidote-rich hydrothermal alteration zones in sheeted dikes and gabbros are clearly highlighted on element maps of S, Fe, Ca, Al, and Zn.

  6. Comparative Evaluation of Flow Quantification across the Atrioventricular Valve in Patients with Functional Univentricular Heart after Fontan's Surgery and Healthy Controls: Measurement by 4D Flow Magnetic Resonance Imaging and Streamline Visualization.

    PubMed

    She, Hoi Lam; Roest, Arno A W; Calkoen, Emmeline E; van den Boogaard, Pieter J; van der Geest, Rob J; Hazekamp, Mark G; de Roos, Albert; Westenberg, Jos J M

    2017-01-01

    To evaluate the inflow pattern and flow quantification in patients with functional univentricular heart after Fontan's operation using 4D flow magnetic resonance imaging (MRI) with streamline visualization when compared with the conventional 2D flow approach. Seven patients with functional univentricular heart after Fontan's operation and twenty-three healthy controls underwent 4D flow MRI. In two orthogonal two-chamber planes, streamline visualization was applied, and inflow angles with peak inflow velocity (PIV) were measured. Transatrioventricular flow quantification was assessed using conventional 2D multiplanar reformation (MPR) and 4D MPR tracking the annulus and perpendicular to the streamline inflow at PIV, and they were validated with net forward aortic flow. Inflow angles at PIV in the patient group demonstrated wide variation of angles and directions when compared with the control group (P < .01). The use of 4D flow MRI with streamlines visualization in quantification of the transatrioventricular flow had smaller limits of agreement (2.2 ± 4.1 mL; 95% limit of agreement -5.9-10.3 mL) when compared with the static plane assessment from 2DFlow MRI (-2.2 ± 18.5 mL; 95% limit of agreement agreement -38.5-34.1 mL). Stronger correlation was present in the 4D flow between the aortic and trans-atrioventricular flow (R 2 correlation in 4D flow: 0.893; in 2D flow: 0.786). Streamline visualization in 4D flow MRI confirmed variable atrioventricular inflow directions in patients with functional univentricular heart with previous Fontan's procedure. 4D flow aided generation of measurement planes according to the blood flood dynamics and has proven to be more accurate than the fixed plane 2D flow measurements when calculating flow quantifications. © 2016 Wiley Periodicals, Inc.

  7. Nucleon Spin Structure and Constituent Quark Model

    NASA Astrophysics Data System (ADS)

    Wang, Fan; Qing, Di; Chen, Xiang-Song; Goldman, T.

    1998-10-01

    The success of the constituent quark model has been challenged by the nucleon spin structure discovered in polarized deep inelastic scattering (DIS). We find that this puzzle is due to misidentifying the axial charge Δ q and the nonrelativistic quark spin. The space component of the quark axial vector current operator, int d^3x\\overlineψ γγ_5ψ =2s_q, defines the quark spin operator s_q, including not only the Pauli spin operator, which corresponds to the nonrelativistic quark spin s_q^NR, but also relativistic and quark-antiquark pair creation (annihilation) correction terms. Both of these suppress the quark spin contribution for a nucleon at rest due to transverse motion of the quark. The relativistic quark orbital angular momentum operator L_q=int d^3x\\overlineψ x× fracpartial iψ includes L^NRq and two correction terms which are exactly the same as those of sq but of opposite sign. They provide compensation which keeps the total nucleon spin frac 12 untouched no matter what kind of quark model is used. Nucleon spin can be decomposed either as s_q+Lq or as s_q^NR+L_q^NR. (The gluon degree of freedom is assumed to be frozen in the nucleon ground state at low energy scales.) The tensor charge δ q=int d^3x\\overlineψ Σ ψ of the nucleon is predicted to have similar but smaller corrections.

  8. Clinical validation of coronal and sagittal spinal curve measurements based on three-dimensional vertebra vector parameters.

    PubMed

    Somoskeöy, Szabolcs; Tunyogi-Csapó, Miklós; Bogyó, Csaba; Illés, Tamás

    2012-10-01

    For many decades, visualization and evaluation of three-dimensional (3D) spinal deformities have only been possible by two-dimensional (2D) radiodiagnostic methods, and as a result, characterization and classification were based on 2D terminologies. Recent developments in medical digital imaging and 3D visualization techniques including surface 3D reconstructions opened a chance for a long-sought change in this field. Supported by a 3D Terminology on Spinal Deformities of the Scoliosis Research Society, an approach for 3D measurements and a new 3D classification of scoliosis yielded several compelling concepts on 3D visualization and new proposals for 3D classification in recent years. More recently, a new proposal for visualization and complete 3D evaluation of the spine by 3D vertebra vectors has been introduced by our workgroup, a concept, based on EOS 2D/3D, a groundbreaking new ultralow radiation dose integrated orthopedic imaging device with sterEOS 3D spine reconstruction software. Comparison of accuracy, correlation of measurement values, intraobserver and interrater reliability of methods by conventional manual 2D and vertebra vector-based 3D measurements in a routine clinical setting. Retrospective, nonrandomized study of diagnostic X-ray images created as part of a routine clinical protocol of eligible patients examined at our clinic during a 30-month period between July 2007 and December 2009. In total, 201 individuals (170 females, 31 males; mean age, 19.88 years) including 10 healthy athletes with normal spine and patients with adolescent idiopathic scoliosis (175 cases), adult degenerative scoliosis (11 cases), and Scheuermann hyperkyphosis (5 cases). Overall range of coronal curves was between 2.4 and 117.5°. Analysis of accuracy and reliability of measurements was carried out on a group of all patients and in subgroups based on coronal plane deviation: 0 to 10° (Group 1; n=36), 10 to 25° (Group 2; n=25), 25 to 50° (Group 3; n=69), 50 to 75° (Group 4; n=49), and above 75° (Group 5; n=22). All study subjects were examined by EOS 2D imaging, resulting in anteroposterior (AP) and lateral (LAT) full spine, orthogonal digital X-ray images, in standing position. Conventional coronal and sagittal curvature measurements including sagittal L5 vertebra wedges were determined by 3 experienced examiners, using traditional Cobb methods on EOS 2D AP and LAT images. Vertebra vector-based measurements were performed as published earlier, based on computer-assisted calculations of corresponding spinal curvature. Vertebra vectors were generated by dedicated software from sterEOS 3D spine models reconstructed from EOS 2D images by the same three examiners. Manual measurements were performed by each examiner, thrice for sterEOS 3D reconstructions and twice for vertebra vector-based measurements. Means comparison t test, Pearson bivariate correlation analysis, reliability analysis by intraclass correlation coefficients for intraobserver reproducibility and interrater reliability were performed using SPSS v16.0 software. In comparison with manual 2D methods, only small and nonsignificant differences were detectable in vertebra vector-based curvature data for coronal curves and thoracic kyphosis, whereas the found difference in L1-L5 lordosis values was shown to be strongly related to the magnitude of corresponding L5 wedge. Intraobserver reliability was excellent for both methods, and interrater reproducibility was consistently higher for vertebra vector-based methods that was also found to be unaffected by the magnitude of coronal curves or sagittal plane deviations. Vertebra vector-based angulation measurements could fully substitute conventional manual 2D measurements, with similar accuracy and higher intraobserver reliability and interrater reproducibility. Vertebra vectors represent a truly 3D solution for clear and comprehensible 3D visualization of spinal deformities while preserving crucial parametric information for vertebral size, 3D position, orientation, and rotation. The concept of vertebra vectors may serve as a starting point to a valid and clinically useful alternative for a new 3D classification of scoliosis. Copyright © 2012 Elsevier Inc. All rights reserved.

  9. An object oriented fully 3D tomography visual toolkit.

    PubMed

    Agostinelli, S; Paoli, G

    2001-04-01

    In this paper we present a modern object oriented component object model (COMM) C + + toolkit dedicated to fully 3D cone-beam tomography. The toolkit allows the display and visual manipulation of analytical phantoms, projection sets and volumetric data through a standard Windows graphical user interface. Data input/output is performed using proprietary file formats but import/export of industry standard file formats, including raw binary, Windows bitmap and AVI, ACR/NEMA DICOMM 3 and NCSA HDF is available. At the time of writing built-in implemented data manipulators include a basic phantom ray-tracer and a Matrox Genesis frame grabbing facility. A COMM plug-in interface is provided for user-defined custom backprojector algorithms: a simple Feldkamp ActiveX control, including source code, is provided as an example; our fast Feldkamp plug-in is also available.

  10. Three-dimensional visualization of the microvasculature of bile duct ligation-induced liver fibrosis in rats by x-ray phase-contrast imaging computed tomography

    NASA Astrophysics Data System (ADS)

    Xuan, Ruijiao; Zhao, Xinyan; Hu, Doudou; Jian, Jianbo; Wang, Tailing; Hu, Chunhong

    2015-07-01

    X-ray phase-contrast imaging (PCI) can substantially enhance contrast, and is particularly useful in differentiating biological soft tissues with small density differences. Combined with computed tomography (CT), PCI-CT enables the acquisition of accurate microstructures inside biological samples. In this study, liver microvasculature was visualized without contrast agents in vitro with PCI-CT using liver fibrosis samples induced by bile duct ligation (BDL) in rats. The histological section examination confirmed the correspondence of CT images with the microvascular morphology of the samples. By means of the PCI-CT and three-dimensional (3D) visualization technique, 3D microvascular structures in samples from different stages of liver fibrosis were clearly revealed. Different types of blood vessels, including portal veins and hepatic veins, in addition to ductular proliferation and bile ducts, could be distinguished with good sensitivity, excellent specificity and excellent accuracy. The study showed that PCI-CT could assess the morphological changes in liver microvasculature that result from fibrosis and allow characterization of the anatomical and pathological features of the microvasculature. With further development of PCI-CT technique, it may become a novel noninvasive imaging technique for the auxiliary analysis of liver fibrosis.

  11. Using a 3D CAD plant model to simplify process hazard reviews

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tolpa, G.

    A Hazard and Operability (HAZOP) review is a formal predictive procedure used to identify potential hazard and operability problems associated with certain processes and facilities. The HAZOP procedure takes place several times during the life cycle of the facility. Replacing plastic models, layout and detail drawings with a 3D CAD electronic model, provides access to process safety information and a detailed level of plant topology that approaches the visualization capability of the imagination. This paper describes the process that is used for adding the use of a 3D CAD model to flowsheets and proven computer programs for the conduct ofmore » hazard and operability reviews. Using flowsheets and study nodes as a road map for the review the need for layout and other detail drawings is all but eliminated. Using the 3D CAD model again for a post-P and ID HAZOP supports conformance to layout and safety requirements, provides superior visualization of the plant configuration and preserves the owners equity in the design. The response from the review teams are overwhelmingly in favor of this type of review over a review that uses only drawings. Over the long term the plant model serves more than just process hazards analysis. Ongoing use of the model can satisfy the required access to process safety information, OHSA documentation and other legal requirements. In this paper extensive instructions address the logic for the process hazards analysis and the preparation required to assist anyone who wishes to add the use of a 3D model to their review.« less

  12. Using component technologies for web based wavelet enhanced mammographic image visualization.

    PubMed

    Sakellaropoulos, P; Costaridou, L; Panayiotakis, G

    2000-01-01

    The poor contrast detectability of mammography can be dealt with by domain specific software visualization tools. Remote desktop client access and time performance limitations of a previously reported visualization tool are addressed, aiming at more efficient visualization of mammographic image resources existing in web or PACS image servers. This effort is also motivated by the fact that at present, web browsers do not support domain-specific medical image visualization. To deal with desktop client access the tool was redesigned by exploring component technologies, enabling the integration of stand alone domain specific mammographic image functionality in a web browsing environment (web adaptation). The integration method is based on ActiveX Document Server technology. ActiveX Document is a part of Object Linking and Embedding (OLE) extensible systems object technology, offering new services in existing applications. The standard DICOM 3.0 part 10 compatible image-format specification Papyrus 3.0 is supported, in addition to standard digitization formats such as TIFF. The visualization functionality of the tool has been enhanced by including a fast wavelet transform implementation, which allows for real time wavelet based contrast enhancement and denoising operations. Initial use of the tool with mammograms of various breast structures demonstrated its potential in improving visualization of diagnostic mammographic features. Web adaptation and real time wavelet processing enhance the potential of the previously reported tool in remote diagnosis and education in mammography.

  13. MorphoGraphX: A platform for quantifying morphogenesis in 4D.

    PubMed

    Barbier de Reuille, Pierre; Routier-Kierzkowska, Anne-Lise; Kierzkowski, Daniel; Bassel, George W; Schüpbach, Thierry; Tauriello, Gerardo; Bajpai, Namrata; Strauss, Sören; Weber, Alain; Kiss, Annamaria; Burian, Agata; Hofhuis, Hugo; Sapala, Aleksandra; Lipowczan, Marcin; Heimlicher, Maria B; Robinson, Sarah; Bayer, Emmanuelle M; Basler, Konrad; Koumoutsakos, Petros; Roeder, Adrienne H K; Aegerter-Wilmsen, Tinri; Nakayama, Naomi; Tsiantis, Miltos; Hay, Angela; Kwiatkowska, Dorota; Xenarios, Ioannis; Kuhlemeier, Cris; Smith, Richard S

    2015-05-06

    Morphogenesis emerges from complex multiscale interactions between genetic and mechanical processes. To understand these processes, the evolution of cell shape, proliferation and gene expression must be quantified. This quantification is usually performed either in full 3D, which is computationally expensive and technically challenging, or on 2D planar projections, which introduces geometrical artifacts on highly curved organs. Here we present MorphoGraphX ( www.MorphoGraphX.org), a software that bridges this gap by working directly with curved surface images extracted from 3D data. In addition to traditional 3D image analysis, we have developed algorithms to operate on curved surfaces, such as cell segmentation, lineage tracking and fluorescence signal quantification. The software's modular design makes it easy to include existing libraries, or to implement new algorithms. Cell geometries extracted with MorphoGraphX can be exported and used as templates for simulation models, providing a powerful platform to investigate the interactions between shape, genes and growth.

  14. OsiriX software as a preoperative planning tool in cranial neurosurgery: A step-by-step guide for neurosurgical residents

    PubMed Central

    Spiriev, Toma; Nakov, Vladimir; Laleva, Lili; Tzekov, Christo

    2017-01-01

    Background: OsiriX (Pixmeo, Switzerland) is an open-source Digital Imaging and Communications in Medicine (DICOM) viewer that is gaining more and more attention in the neurosurgical community because of its user-friendly interface, powerful three-dimensional (3D) volumetric rendering capabilities, and various options for data integration. This paper presents in detail the use of OsiriX software as a preoperative planning tool in cranial neurosurgery. Methods: In January 2013, OsiriX software was introduced into our clinical practice as a preoperative planning tool. Its capabilities are being evaluated on an ongoing basis in routine elective cranial cases. Results: The program has proven to be highly effective at volumetrically representing data from radiological examinations in 3D. Among its benefits in preoperative planning are simulating the position and exact location of the lesion in 3D, tailoring the skin incision and craniotomy bone flap, enhancing the representation of normal and pathological anatomy, and aiding in planning the reconstruction of the affected area. Conclusion: OsiriX is a useful tool for preoperative planning and visualization in neurosurgery. The software greatly facilitates the surgeon's understanding of the relationship between normal and pathological anatomy and can be used as a teaching tool. PMID:29119039

  15. Simulation on an optimal combustion control strategy for 3-D temperature distributions in tangentially pc-fired utility boiler furnaces.

    PubMed

    Wang, Xi-fen; Zhou, Huai-chun

    2005-01-01

    The control of 3-D temperature distribution in a utility boiler furnace is essential for the safe, economic and clean operation of pc-fired furnace with multi-burner system. The development of the visualization of 3-D temperature distributions in pc-fired furnaces makes it possible for a new combustion control strategy directly with the furnace temperature as its goal to improve the control quality for the combustion processes. Studied in this paper is such a new strategy that the whole furnace is divided into several parts in the vertical direction, and the average temperature and its bias from the center in every cross section can be extracted from the visualization results of the 3-D temperature distributions. In the simulation stage, a computational fluid dynamics (CFD) code served to calculate the 3-D temperature distributions in a furnace, then a linear model was set up to relate the features of the temperature distributions with the input of the combustion processes, such as the flow rates of fuel and air fed into the furnaces through all the burners. The adaptive genetic algorithm was adopted to find the optimal combination of the whole input parameters which ensure to form an optimal 3-D temperature field in the furnace desired for the operation of boiler. Simulation results showed that the strategy could soon find the factors making the temperature distribution apart from the optimal state and give correct adjusting suggestions.

  16. DSSR-enhanced visualization of nucleic acid structures in Jmol

    PubMed Central

    Hanson, Robert M.

    2017-01-01

    Abstract Sophisticated and interactive visualizations are essential for making sense of the intricate 3D structures of macromolecules. For proteins, secondary structural components are routinely featured in molecular graphics visualizations. However, the field of RNA structural bioinformatics is still lagging behind; for example, current molecular graphics tools lack built-in support even for base pairs, double helices, or hairpin loops. DSSR (Dissecting the Spatial Structure of RNA) is an integrated and automated command-line tool for the analysis and annotation of RNA tertiary structures. It calculates a comprehensive and unique set of features for characterizing RNA, as well as DNA structures. Jmol is a widely used, open-source Java viewer for 3D structures, with a powerful scripting language. JSmol, its reincarnation based on native JavaScript, has a predominant position in the post Java-applet era for web-based visualization of molecular structures. The DSSR-Jmol integration presented here makes salient features of DSSR readily accessible, either via the Java-based Jmol application itself, or its HTML5-based equivalent, JSmol. The DSSR web service accepts 3D coordinate files (in mmCIF or PDB format) initiated from a Jmol or JSmol session and returns DSSR-derived structural features in JSON format. This seamless combination of DSSR and Jmol/JSmol brings the molecular graphics of 3D RNA structures to a similar level as that for proteins, and enables a much deeper analysis of structural characteristics. It fills a gap in RNA structural bioinformatics, and is freely accessible (via the Jmol application or the JSmol-based website http://jmol.x3dna.org). PMID:28472503

  17. Split-Ring Resonator Loaded Miniaturised Slot for the Slotted Waveguide Antenna Stiffened Structure

    DTIC Science & Technology

    2011-03-01

    explains the material analysis of BST varactors using the new sputterer so the varactors can be fabricated at RMIT university and utilised for the SRR...44-0093 (*) - Barium Strontium Titanium Oxide - Ba0.77Sr0.23TiO3 - Y: 0.10 % - d x by: 1. - WL: 1.5406 - Tetragonal - Operations: Import D:\\Sensors...unknown unknown BST on sapphire - 2 44-0093 (*) - Barium Strontium Titanium Oxide - Ba0.77Sr0.23TiO3 - Y: 0.10 % - d x by: 1. - WL: 1.5406 - 0

  18. Presurgical visualization of the neurovascular relationship in trigeminal neuralgia with 3D modeling using free Slicer software.

    PubMed

    Han, Kai-Wei; Zhang, Dan-Feng; Chen, Ji-Gang; Hou, Li-Jun

    2016-11-01

    To explore whether segmentation and 3D modeling are more accurate in the preoperative detection of the neurovascular relationship (NVR) in patients with trigeminal neuralgia (TN) compared to MRI fast imaging employing steady-state acquisition (FIESTA). Segmentation and 3D modeling using 3D Slicer were conducted for 40 patients undergoing MRI FIESTA and microsurgical vascular decompression (MVD). The NVR, as well as the offending vessel determined by MRI FIESTA and 3D Slicer, was reviewed and compared with intraoperative manifestations using SPSS. The k agreement between the MRI FIESTA and operation in determining the NVR was 0.232 and that between the 3D modeling and operation was 0.6333. There was no significant difference between these two procedures (χ 2  = 8.09, P = 0.088). The k agreement between the MRI FIESTA and operation in determining the offending vessel was 0.373, and that between the 3D modeling and operation was 0.922. There were significant differences between two of them (χ 2  = 82.01, P = 0.000). The sensitivity and specificity for MRI FIESTA in determining the NVR were 87.2 % and 100 %, respectively, and for 3D modeling were both 100 %. The segmentation and 3D modeling were more accurate than MRI FIESTA in preoperative verification of the NVR and offending vessel. This was consistent with surgical manifestations and was more helpful for the preoperative decision and surgical plan.

  19. Visual search behaviour during laparoscopic cadaveric procedures

    NASA Astrophysics Data System (ADS)

    Dong, Leng; Chen, Yan; Gale, Alastair G.; Rees, Benjamin; Maxwell-Armstrong, Charles

    2014-03-01

    Laparoscopic surgery provides a very complex example of medical image interpretation. The task entails: visually examining a display that portrays the laparoscopic procedure from a varying viewpoint; eye-hand coordination; complex 3D interpretation of the 2D display imagery; efficient and safe usage of appropriate surgical tools, as well as other factors. Training in laparoscopic surgery typically entails practice using surgical simulators. Another approach is to use cadavers. Viewing previously recorded laparoscopic operations is also a viable additional approach and to examine this a study was undertaken to determine what differences exist between where surgeons look during actual operations and where they look when simply viewing the same pre-recorded operations. It was hypothesised that there would be differences related to the different experimental conditions; however the relative nature of such differences was unknown. The visual search behaviour of two experienced surgeons was recorded as they performed three types of laparoscopic operations on a cadaver. The operations were also digitally recorded. Subsequently they viewed the recording of their operations, again whilst their eye movements were monitored. Differences were found in various eye movement parameters when the two surgeons performed the operations and where they looked when they simply watched the recordings of the operations. It is argued that this reflects the different perceptual motor skills pertinent to the different situations. The relevance of this for surgical training is explored.

  20. Parametric study of the 5d3, 5d2 6 s and 5d2 6 p configurations in the Lu I isoelectronic sequence (Ta III-Hg X) using orthogonal operators

    NASA Astrophysics Data System (ADS)

    Azarov, Vladimir I.

    2018-01-01

    Data available on the 5d3, 5d26s and 5d26p configurations in the Lu I isoelectronic sequence have been critically reviewed by means of calculations with the orthogonal operators. The study included spectra from Ta III through Hg X. The calculations agree very well with the experimental data. The isoelectronic behavior of parameters and deviations of the experimental levels from the calculated positions, ΔE = (Eexp -Ecalc), show regular trends. Three missing 5d26s levels have been accurately predicted theoretically and confirmed experimentally: the level (3P)2P3/2 in Pt VIII and the levels (3P)4P5/2 and (3P)2P1/2 in Os VI have been determined in the study. The research suggested revision of the published initial analyses of the Re V and Hg X spectra. The recently completed revised analysis of Re V has confirmed the issues noticed in the initial analysis and has resulted in the data that fit very well in the current parametric study. The isoelectronic evolution of the higher order interactions was studied for the first time in the Lu I sequence. The study included the parameters Ac, A3-A6 describing two-particle magnetic interaction of the dd-type, the parameter Amso describing two-particle magnetic ds-type effect, the parameter Tdds describing 3-particle electrostatic ds-type interaction, and the effective parameters S1 and S2 of the dp-type.

  1. Visualization of Metal Ion Buffering via Three-Dimensional Topographic Surfaces (Topos) of Complexometric Titrations

    ERIC Educational Resources Information Center

    Smith, Garon C.; Hossain, Md Mainul

    2017-01-01

    "Complexation TOPOS" is a free software package to generate 3-D topographic surfaces ("topos") for metal-ligand complexometric titrations in aqueous media. It constructs surfaces by plotting computed equilibrium parameters above a composition grid with "volume of ligand added" as the x-axis and overall system dilution…

  2. Multi-modality 3D breast imaging with X-Ray tomosynthesis and automated ultrasound.

    PubMed

    Sinha, Sumedha P; Roubidoux, Marilyn A; Helvie, Mark A; Nees, Alexis V; Goodsitt, Mitchell M; LeCarpentier, Gerald L; Fowlkes, J Brian; Chalek, Carl L; Carson, Paul L

    2007-01-01

    This study evaluated the utility of 3D automated ultrasound in conjunction with 3D digital X-Ray tomosynthesis for breast cancer detection and assessment, to better localize and characterize lesions in the breast. Tomosynthesis image volumes and automated ultrasound image volumes were acquired in the same geometry and in the same view for 27 patients. 3 MQSA certified radiologists independently reviewed the image volumes, visually correlating the images from the two modalities with in-house software. More sophisticated software was used on a smaller set of 10 cases, which enabled the radiologist to draw a 3D box around the suspicious lesion in one image set and isolate an anatomically correlated, similarly boxed region in the other modality image set. In the primary study, correlation was found to be moderately useful to the readers. In the additional study, using improved software, the median usefulness rating increased and confidence in localizing and identifying the suspicious mass increased in more than half the cases. As automated scanning and reading software techniques advance, superior results are expected.

  3. Stereoscopy and the Human Visual System

    PubMed Central

    Banks, Martin S.; Read, Jenny C. A.; Allison, Robert S.; Watt, Simon J.

    2012-01-01

    Stereoscopic displays have become important for many applications, including operation of remote devices, medical imaging, surgery, scientific visualization, and computer-assisted design. But the most significant and exciting development is the incorporation of stereo technology into entertainment: specifically, cinema, television, and video games. In these applications for stereo, three-dimensional (3D) imagery should create a faithful impression of the 3D structure of the scene being portrayed. In addition, the viewer should be comfortable and not leave the experience with eye fatigue or a headache. Finally, the presentation of the stereo images should not create temporal artifacts like flicker or motion judder. This paper reviews current research on stereo human vision and how it informs us about how best to create and present stereo 3D imagery. The paper is divided into four parts: (1) getting the geometry right, (2) depth cue interactions in stereo 3D media, (3) focusing and fixating on stereo images, and (4) how temporal presentation protocols affect flicker, motion artifacts, and depth distortion. PMID:23144596

  4. Air and Space Operations Center (AOC) Facility Design Guidelines: A Human Factors Engineering Perspective

    DTIC Science & Technology

    2006-07-01

    31 July 1995 3. Human Engineering Guide to Equipment Design, Department of Defense, Washington D.C., 1972 4. American National Standard for Human Factors Engineering of Visual Display Terminal Workstations , ANSI

  5. Effect of supplemental vitamin D3 concentration on concentrations of calcium, phosphorus, and magnesium relative to protein in subcellular components of the longissimus and the distribution of calcium within longissimus muscle of beef steers.

    PubMed

    Montgomery, J L; Blanton, J R; Horst, R L; Galyean, M L; Morrow, K J; Allen, V G; Wester, D B; Miller, M F

    2004-09-01

    The effect of supplementing diets with various levels of vitamin D3 to provide 0, 0.5, 1, and 5 million IU/(steer x d) for 8 d before slaughter on the mineral content and localization of Ca in LM and muscle fragments was studied during the postmortem aging process. Twelve feedlot steers of three biological types were given access to the four levels of vitamin D for 8 d before slaughter. Differential centrifugation techniques were used to determine the concentrations of minerals relative to protein in different muscle fragments on d 3 and 21 postmortem. Electron microscopy visualization of bound Ca indicated that vitamin D3 mobilized Ca from the sarcoplasmic reticulum and transverse tubule system into the myofibrils. Bound Ca was concentrated near the Z-line at the A-band/I-band juncture within the sarcomere. Supplementing steers with 1 and 5 million IU/(steer x d) of vitamin D3 increased (P < 0.05) Ca, P, and Mg concentrations per unit of protein in the cytosol. Soluble cytosolic Ca concentrations were greater (P < 0.05) on d 21 than on d 3 postmortem only when steers were supplemented with 5 million IU/d. Concentrations of Ca, P, and Mg in isolated tissues were increased (P < 0.05) in nuclei and myofibrilar proteins by supplementing steers with 1 and 5 million IU/ (steer x d) of vitamin D3. All supplemental vitamin D3 treatments also increased (P < 0.001) Mg concentrations in the cytosol, regardless of aging treatment, and increased Mg concentrations (P < 0.04) within the mitochondria at d 3 postmortem. Thus, supplementation of feedlot steers with vitamin D3 at levels of 0.5 to 5 million IU/(steer x d) increased Ca concentrations within respiring muscle, resulting in increased bound tissue Ca concentrations. When the respiring muscle was converted to meat, the increased bound tissue Ca resulting from vitamin D3 treatment released Ca concentrations into the cytosol during aging (P < 0.05). Results of this study indicate that vitamin D3 supplementation increased total cytosolic Ca, P, and Mg concentrations in meat.

  6. Outcomes of LASIK for Myopia or Myopic Astigmatism Correction with the FS200 Femtosecond Laser and EX500 Excimer Laser Platform

    PubMed Central

    Niparugs, Muanploy; Tananuvat, Napaporn; Chaidaroon, Winai; Tangmonkongvoragul, Chulaluck; Ausayakhun, Somsanguan

    2018-01-01

    Purpose: To evaluate the efficacy, predictability, stability and safety of laser in situ keratomileusis (LASIK) using the FS200 femtosecond laser and EX500 excimer laser platform. Methods: The outcomes of 254 eyes of 129 consecutive patients with myopia or myopic astigmatism who underwent full correction femtosecond laser-assisted LASIK at CMU LASIK Center were assessed. Pre-operative and post-operative parameters including manifest refraction, Uncorrected Distance Visual Acuity (UDVA), Best Corrected Distance Visual Acuity (BDVA), corneal topography and tomography were analyzed. The results between low to moderate myopia and high myopia were compared up to 12 months. Results: Mean pre-operative Spherical Equivalent (SE) was -5.15±2.41 Diopters (D) (range -0.50 to -11.50 D) and -0.13±0.28 D, -0.13±0.27 D, -0.13±0.28 D and -0.14±0.30 D at 1, 3, 6, and 12 months, post-operatively. At 12 months, the propor¬tion of eyes achieving UDVA ≥ 20/20 was 90.0% and ≥20/40 was 98.8%. The proportion of eyes achieving post-operative mean SE ±0.5 D, and ±1 D was 91.3%, and 98.5%. No eyes lost more than two lines of BDVA. The low to moderate myopic group had a statistically significant better UDVA at one (p=0.017) and three months (p=0.014) but no difference at six (p=0.061) and 12 months (p=0.091). The mean post-operative SE was better in low to moderate myopic group at every follow-up visit (p=0.001, 0.007, <0.001 and <0.001). Conclusion: One-year clinical results of LASIK with the FS200 femtosecond laser and EX500 excimer laser showed high efficacy, predictability, stability and safety. PMID:29872485

  7. Analysis of Visual Illusions Using Multiresolution Wavelet Decomposition Based Models

    DTIC Science & Technology

    1991-12-01

    1962). 22. Hubel , David H. "The Visual Cortex of The Brain," Scientific American, 209(5):54-62 (November 1963). 23. Hubel , David H. and Torsten N...model the visual system. In 1990, Oberndorf, a masters student at the Air Force Institrt, of Technology, tested the Gabor theo y on visual illusion...represento d by x2 + y2 = r 2 in Cartesian space is now more easily expressed by p = r in polar space. The coordinates x and y or p and 0 provide alternate

  8. Approximation of a foreign object using x-rays, reference photographs and 3D reconstruction techniques.

    PubMed

    Briggs, Matt; Shanmugam, Mohan

    2013-12-01

    This case study describes how a 3D animation was created to approximate the depth and angle of a foreign object (metal bar) that had become embedded into a patient's head. A pre-operative CT scan was not available as the patient could not fit though the CT scanner, therefore a post surgical CT scan, x-ray and photographic images were used. A surface render was made of the skull and imported into Blender (a 3D animation application). The metal bar was not available, however images of a similar object that was retrieved from the scene by the ambulance crew were used to recreate a 3D model. The x-ray images were then imported into Blender and used as background images in order to align the skull reconstruction and metal bar at the correct depth/angle. A 3D animation was then created to fully illustrate the angle and depth of the iron bar in the skull.

  9. Scalable large format 3D displays

    NASA Astrophysics Data System (ADS)

    Chang, Nelson L.; Damera-Venkata, Niranjan

    2010-02-01

    We present a general framework for the modeling and optimization of scalable large format 3-D displays using multiple projectors. Based on this framework, we derive algorithms that can robustly optimize the visual quality of an arbitrary combination of projectors (e.g. tiled, superimposed, combinations of the two) without manual adjustment. The framework creates for the first time a new unified paradigm that is agnostic to a particular configuration of projectors yet robustly optimizes for the brightness, contrast, and resolution of that configuration. In addition, we demonstrate that our algorithms support high resolution stereoscopic video at real-time interactive frame rates achieved on commodity graphics hardware. Through complementary polarization, the framework creates high quality multi-projector 3-D displays at low hardware and operational cost for a variety of applications including digital cinema, visualization, and command-and-control walls.

  10. Navigation for fluoroscopy-guided cryo-balloon ablation procedures of atrial fibrillation

    NASA Astrophysics Data System (ADS)

    Bourier, Felix; Brost, Alexander; Kleinoeder, Andreas; Kurzendorfer, Tanja; Koch, Martin; Kiraly, Attila; Schneider, Hans-Juergen; Hornegger, Joachim; Strobel, Norbert; Kurzidim, Klaus

    2012-02-01

    Atrial fibrillation (AFib), the most common arrhythmia, has been identified as a major cause of stroke. The current standard in interventional treatment of AFib is the pulmonary vein isolation (PVI). PVI is guided by fluoroscopy or non-fluoroscopic electro-anatomic mapping systems (EAMS). Either classic point-to-point radio-frequency (RF)- catheter ablation or so-called single-shot-devices like cryo-balloons are used to achieve electrically isolation of the pulmonary veins and the left atrium (LA). Fluoroscopy-based systems render overlay images from pre-operative 3-D data sets which are then merged with fluoroscopic imaging, thereby adding detailed 3-D information to conventional fluoroscopy. EAMS provide tracking and visualization of RF catheters by means of electro-magnetic tracking. Unfortunately, current navigation systems, fluoroscopy-based or EAMS, do not provide tools to localize and visualize single shot devices like cryo-balloon catheters in 3-D. We present a prototype software for fluoroscopy-guided ablation procedures that is capable of superimposing 3-D datasets as well as reconstructing cyro-balloon catheters in 3-D. The 3-D cyro-balloon reconstruction was evaluated on 9 clinical data sets, yielded a reprojected 2-D error of 1.72 mm +/- 1.02 mm.

  11. Control and Guidance of Low-Cost Robots via Gesture Perception for Monitoring Activities in the Home

    PubMed Central

    Sempere, Angel D.; Serna-Leon, Arturo; Gil, Pablo; Puente, Santiago; Torres, Fernando

    2015-01-01

    This paper describes the development of a low-cost mini-robot that is controlled by visual gestures. The prototype allows a person with disabilities to perform visual inspections indoors and in domestic spaces. Such a device could be used as the operator's eyes obviating the need for him to move about. The robot is equipped with a motorised webcam that is also controlled by visual gestures. This camera is used to monitor tasks in the home using the mini-robot while the operator remains quiet and motionless. The prototype was evaluated through several experiments testing the ability to use the mini-robot’s kinematics and communication systems to make it follow certain paths. The mini-robot can be programmed with specific orders and can be tele-operated by means of 3D hand gestures to enable the operator to perform movements and monitor tasks from a distance. PMID:26690448

  12. Accurate micro-computed tomography imaging of pore spaces in collagen-based scaffold.

    PubMed

    Zidek, Jan; Vojtova, Lucy; Abdel-Mohsen, A M; Chmelik, Jiri; Zikmund, Tomas; Brtnikova, Jana; Jakubicek, Roman; Zubal, Lukas; Jan, Jiri; Kaiser, Jozef

    2016-06-01

    In this work we have used X-ray micro-computed tomography (μCT) as a method to observe the morphology of 3D porous pure collagen and collagen-composite scaffolds useful in tissue engineering. Two aspects of visualizations were taken into consideration: improvement of the scan and investigation of its sensitivity to the scan parameters. Due to the low material density some parts of collagen scaffolds are invisible in a μCT scan. Therefore, here we present different contrast agents, which increase the contrast of the scanned biopolymeric sample for μCT visualization. The increase of contrast of collagenous scaffolds was performed with ceramic hydroxyapatite microparticles (HAp), silver ions (Ag(+)) and silver nanoparticles (Ag-NPs). Since a relatively small change in imaging parameters (e.g. in 3D volume rendering, threshold value and μCT acquisition conditions) leads to a completely different visualized pattern, we have optimized these parameters to obtain the most realistic picture for visual and qualitative evaluation of the biopolymeric scaffold. Moreover, scaffold images were stereoscopically visualized in order to better see the 3D biopolymer composite scaffold morphology. However, the optimized visualization has some discontinuities in zoomed view, which can be problematic for further analysis of interconnected pores by commonly used numerical methods. Therefore, we applied the locally adaptive method to solve discontinuities issue. The combination of contrast agent and imaging techniques presented in this paper help us to better understand the structure and morphology of the biopolymeric scaffold that is crucial in the design of new biomaterials useful in tissue engineering.

  13. Visualization of scoliotic spine using ultrasound-accessible skeletal landmarks

    NASA Astrophysics Data System (ADS)

    Church, Ben; Lasso, Andras; Schlenger, Christopher; Borschneck, Daniel P.; Mousavi, Parvin; Fichtinger, Gabor; Ungi, Tamas

    2017-03-01

    PURPOSE: Ultrasound imaging is an attractive alternative to X-ray for scoliosis diagnosis and monitoring due to its safety and inexpensiveness. The transverse processes as skeletal landmarks are accessible by means of ultrasound and are sufficient for quantifying scoliosis, but do not provide an informative visualization of the spine. METHODS: We created a method for visualization of the scoliotic spine using a 3D transform field, resulting from thin-spline interpolation of a landmark-based registration between the transverse processes that we localized in both the patient's ultrasound and an average healthy spine model. Additional anchor points were computationally generated to control the thin-spline interpolation, in order to gain a transform field that accurately represents the deformation of the patient's spine. The transform field is applied to the average spine model, resulting in a 3D surface model depicting the patient's spine. We applied ground truth CT from pediatric scoliosis patients in which we reconstructed the bone surface and localized the transverse processes. We warped the average spine model and analyzed the match between the patient's bone surface and the warped spine. RESULTS: Visual inspection revealed accurate rendering of the scoliotic spine. Notable misalignments occurred mainly in the anterior-posterior direction, and at the first and last vertebrae, which is immaterial for scoliosis quantification. The average Hausdorff distance computed for 4 patients was 2.6 mm. CONCLUSIONS: We achieved qualitatively accurate and intuitive visualization to depict the 3D deformation of the patient's spine when compared to ground truth CT.

  14. 3D nanoscale imaging of the yeast, Schizosaccharomyces pombe, by full-field transmission x-ray microscopy at 5.4 keV

    PubMed Central

    Chen, Jie; Yang, Yunhao; Zhang, Xiaobo; Andrews, Joy C.; Pianetta, Piero; Guan, Yong; Liu, Gang; Xiong, Ying; Wu, Ziyu; Tian, Yangchao

    2010-01-01

    Three-dimensional (3D) nanoscale structures of the fission yeast, Schizosaccharomyces pombe, can be obtained by full-field transmission hard x-ray microscopy with 30 nm resolution using synchrotron radiation sources. Sample preparation is relatively simple and the samples are portable across various imaging environments, allowing for high throughput sample screening. The yeast cells were fixed and double stained with Reynold’s lead citrate and uranyl acetate. We performed both absorption contrast and Zernike phase contrast imaging on these cells in order to test this method. The membranes, nucleus and subcellular organelles of the cells were clearly visualized using absorption contrast mode. The x-ray images of the cells could be used to study the spatial distributions of the organelles in the cells. These results show unique structural information, demonstrating that hard x-ray microscopy is a complementary method for imaging and analyzing biological samples. PMID:20349228

  15. Video-Game-Like Engine for Depicting Spacecraft Trajectories

    NASA Technical Reports Server (NTRS)

    Upchurch, Paul R.

    2009-01-01

    GoView is a video-game-like software engine, written in the C and C++ computing languages, that enables real-time, three-dimensional (3D)-appearing visual representation of spacecraft and trajectories (1) from any perspective; (2) at any spatial scale from spacecraft to Solar-system dimensions; (3) in user-selectable time scales; (4) in the past, present, and/or future; (5) with varying speeds; and (6) forward or backward in time. GoView constructs an interactive 3D world by use of spacecraft-mission data from pre-existing engineering software tools. GoView can also be used to produce distributable application programs for depicting NASA orbital missions on personal computers running the Windows XP, Mac OsX, and Linux operating systems. GoView enables seamless rendering of Cartesian coordinate spaces with programmable graphics hardware, whereas prior programs for depicting spacecraft trajectories variously require non-Cartesian coordinates and/or are not compatible with programmable hardware. GoView incorporates an algorithm for nonlinear interpolation between arbitrary reference frames, whereas the prior programs are restricted to special classes of inertial and non-inertial reference frames. Finally, whereas the prior programs present complex user interfaces requiring hours of training, the GoView interface provides guidance, enabling use without any training.

  16. Raised Relief Mars Globe Brings the Red Planet Closer

    NASA Technical Reports Server (NTRS)

    2006-01-01

    The Mars Globe 20x is the first digitally produced raised relief globe to be sold at retail establishments. The rises and dips of the Martian landscape have been multiplied by 20 to make the shapes more noticeable to human touch and sight. They make this globe, with its over 1 million elevation points, a visually stunning introduction to the planet. Spectrum 3D used the NASA digital land elevation data to aim lasers that then shaped and defined the master globe s surface. Subsequent copies were then made by creating a master globe mold. The molded copies are hand finished by workers who remove errant edges or lines that may appear on the raw globes and then paint the surfaces. The result is a globe that measures in at 18 inches in diameter, roughly 1:15,729,473 scale of the actual planet. The exaggerated raised relief is like having a 3-D digital microscope for planetary shapes. This makes the landmarks easier to learn and understand, as it provides easy visuals for orientation. People have a natural propensity for understanding 3-D shapes more easily than numbers or words. The 3-D globes appeal to both the kinetic and visual learning aspects of the brain, making it easy for people to readily memorize the landmarks and to make a mental model that they will remember for a long time.

  17. Generalized centripetal force law and quantization of motion constrained on 2D surfaces

    NASA Astrophysics Data System (ADS)

    Liu, Q. H.; Zhang, J.; Lian, D. K.; Hu, L. D.; Li, Z.

    2017-03-01

    For a particle of mass μ moves on a 2D surface f(x) = 0 embedded in 3D Euclidean space of coordinates x, there is an open and controversial problem whether the Dirac's canonical quantization scheme for the constrained motion allows for the geometric potential that has been experimentally confirmed. We note that the Dirac's scheme hypothesizes that the symmetries indicated by classical brackets among positions x and momenta p and Hamiltonian Hc remain in quantum mechanics, i.e., the following Dirac brackets [ x ,Hc ] D and [ p ,Hc ] D holds true after quantization, in addition to the fundamental ones [ x , x ] D, [ x , p ] D and [ p , p ] D. This set of hypotheses implies that the Hamiltonian operator is simultaneously determined during the quantization. The quantum mechanical relations corresponding to the classical mechanical ones p / μ =[ x ,Hc ] D directly give the geometric momenta. The time t derivative of the momenta p ˙ =[ p ,Hc ] D in classical mechanics is in fact the generalized centripetal force law for particle on the 2D surface, which in quantum mechanics permits both the geometric momenta and the geometric potential.

  18. Proceedings of the DoD Workload Assessment Workshop on Workload Assessment Techniques and Tools Held in Dayton Ohio on 27-28 September 1986.

    DTIC Science & Technology

    1987-09-15

    memory task. Subjects in the experiment were required to monitor a visual display and update the status of four categories of information that changed ...Kahneman, D., 1966, Pupillary changes in two memory tasks, Psychonomic Science, 55:371-372. Casali, J. G. and Wierwille, W. W., 1982, A sensitivity...operator to deal with the demands. 3. The level of operator performance that results from the inter - action of task demands and capacity/effort

  19. 3D visualization software to analyze topological outcomes of topoisomerase reactions

    PubMed Central

    Darcy, I. K.; Scharein, R. G.; Stasiak, A.

    2008-01-01

    The action of various DNA topoisomerases frequently results in characteristic changes in DNA topology. Important information for understanding mechanistic details of action of these topoisomerases can be provided by investigating the knot types resulting from topoisomerase action on circular DNA forming a particular knot type. Depending on the topological bias of a given topoisomerase reaction, one observes different subsets of knotted products. To establish the character of topological bias, one needs to be aware of all possible topological outcomes of intersegmental passages occurring within a given knot type. However, it is not trivial to systematically enumerate topological outcomes of strand passage from a given knot type. We present here a 3D visualization software (TopoICE-X in KnotPlot) that incorporates topological analysis methods in order to visualize, for example, knots that can be obtained from a given knot by one intersegmental passage. The software has several other options for the topological analysis of mechanisms of action of various topoisomerases. PMID:18440983

  20. Visualizing and enhancing a deep learning framework using patients age and gender for chest x-ray image retrieval

    NASA Astrophysics Data System (ADS)

    Anavi, Yaron; Kogan, Ilya; Gelbart, Elad; Geva, Ofer; Greenspan, Hayit

    2016-03-01

    We explore the combination of text metadata, such as patients' age and gender, with image-based features, for X-ray chest pathology image retrieval. We focus on a feature set extracted from a pre-trained deep convolutional network shown in earlier work to achieve state-of-the-art results. Two distance measures are explored: a descriptor-based measure, which computes the distance between image descriptors, and a classification-based measure, which performed by a comparison of the corresponding SVM classification probabilities. We show that retrieval results increase once the age and gender information combined with the features extracted from the last layers of the network, with best results using the classification-based scheme. Visualization of the X-ray data is presented by embedding the high dimensional deep learning features in a 2-D dimensional space while preserving the pairwise distances using the t-SNE algorithm. The 2-D visualization gives the unique ability to find groups of X-ray images that are similar to the query image and among themselves, which is a characteristic we do not see in a 1-D traditional ranking.

  1. Vergence-accommodation conflicts hinder visual performance and cause visual fatigue.

    PubMed

    Hoffman, David M; Girshick, Ahna R; Akeley, Kurt; Banks, Martin S

    2008-03-28

    Three-dimensional (3D) displays have become important for many applications including vision research, operation of remote devices, medical imaging, surgical training, scientific visualization, virtual prototyping, and more. In many of these applications, it is important for the graphic image to create a faithful impression of the 3D structure of the portrayed object or scene. Unfortunately, 3D displays often yield distortions in perceived 3D structure compared with the percepts of the real scenes the displays depict. A likely cause of such distortions is the fact that computer displays present images on one surface. Thus, focus cues-accommodation and blur in the retinal image-specify the depth of the display rather than the depths in the depicted scene. Additionally, the uncoupling of vergence and accommodation required by 3D displays frequently reduces one's ability to fuse the binocular stimulus and causes discomfort and fatigue for the viewer. We have developed a novel 3D display that presents focus cues that are correct or nearly correct for the depicted scene. We used this display to evaluate the influence of focus cues on perceptual distortions, fusion failures, and fatigue. We show that when focus cues are correct or nearly correct, (1) the time required to identify a stereoscopic stimulus is reduced, (2) stereoacuity in a time-limited task is increased, (3) distortions in perceived depth are reduced, and (4) viewer fatigue and discomfort are reduced. We discuss the implications of this work for vision research and the design and use of displays.

  2. High-contrast X-ray micro-radiography and micro-CT of ex-vivo soft tissue murine organs utilizing ethanol fixation and large area photon-counting detector

    PubMed Central

    Dudak, Jan; Zemlicka, Jan; Karch, Jakub; Patzelt, Matej; Mrzilkova, Jana; Zach, Petr; Hermanova, Zuzana; Kvacek, Jiri; Krejci, Frantisek

    2016-01-01

    Using dedicated contrast agents high-quality X-ray imaging of soft tissue structures with isotropic micrometre resolution has become feasible. This technique is frequently titled as virtual histology as it allows production of slices of tissue without destroying the sample. The use of contrast agents is, however, often an irreversible time-consuming procedure and despite the non-destructive principle of X-ray imaging, the sample is usually no longer usable for other research methods. In this work we present the application of recently developed large-area photon counting detector for high resolution X-ray micro-radiography and micro-tomography of whole ex-vivo ethanol-preserved mouse organs. The photon counting detectors provide dark-current-free quantum-counting operation enabling acquisition of data with virtually unlimited contrast-to-noise ratio (CNR). Thanks to the very high CNR even ethanol-only preserved soft-tissue samples without addition of any contrast agent can be visualized in great detail. As ethanol preservation is one of the standard steps of tissue fixation for histology, the presented method can open a way for widespread use of micro-CT with all its advantages for routine 3D non-destructive soft-tissue visualisation. PMID:27461900

  3. A 3-D terrain visualization database for highway information management

    DOT National Transportation Integrated Search

    1999-07-26

    A Multimedia based Highway Information System (MMHIS) is described in the paper to improve the existing photologging system for various operation and management needs. The full digital, computer based MMHIS uses technologies of video, multimedia data...

  4. Spatial variability of litter gaseous flux within a commercial broiler house: ammonia, nitrous oxide, carbon dioxide, and methane.

    PubMed

    Miles, D M; Owens, P R; Rowe, D E

    2006-02-01

    Twenty-eight flocks were grown on litter in a tunnel-ventilated, curtain-sided commercial broiler house prior to this summer flock. Grid measurements were made using a photo-acoustic multigas analyzer to assess the spatial variability of litter gases (NH3, N2O, CO2, and CH4) on d 1 and 21. The pooled results for the brood and non-brood areas of the house were 1) NH3 flux was greatest in the brood area at d 1, averaging 497 mg/(m2 x h), and had a mean of 370 mg/(m2 x h) in the vacant end of the house; 2) at d 21, the non-brood area had the greater average NH3 flux, 310 mg/(m2 x h), and flux in the brood area was 136 mg/(m2 x h); 3) N2O and CH4 fluxes were <60 mg/(m2 x h); and 4) on d 1, brood CO2 flux was 6,190 mg/(m2 x h) compared with 5,490 mg/ (m2 x h) at the opposite end of the house. On d 21, these values increased to 6,540 and 9,684 mg/(m2 x h) for the brood and non-brood areas. Ammonia flux seemed most affected by litter temperature. Carbon dioxide and CH4 increased from placement to mid growout, corresponding to increased moisture, especially near the fans. Contour plots were developed using geostatistical software to visually assess the spatial disparity among the measurements. This research provides a unique view of gas flux variation within the house. Collinear factors such as house management, bird size and age, and amount of deposition are significant factors for litter gas flux and should be considered in comprehensive models for emission estimates.

  5. Label-free and highly sensitive optical imaging of detailed microcirculation within meninges and cortex in mice with the cranium left intact.

    PubMed

    Jia, Yali; An, Lin; Wang, Ruikang K

    2010-01-01

    We demonstrate for the first time that the detailed blood flow distribution within intracranial dura mater and cortex can be visualized by an ultrahigh sensitive optical microangiography (UHS-OMAG). The study uses an UHS-OMAG system operating at 1310 nm with an imaging speed at 150 frames per second that requires approximately 10 s to complete one 3-D scan of approximately 2.5 x 2.5 mm(2). The system is sensitive to blood flow with a velocity ranging from approximately 4 microms to approximately 23 mms. We show superior performance of UHS-OMAG in providing functional images of capillary level microcirculation within meninges in mice with the cranium left intact, the results of which correlate well with the standard dural histopathology.

  6. Using synchrotron X-ray phase-contrast micro-computed tomography to study tissue damage by laser irradiation.

    PubMed

    Robinson, Alan M; Stock, Stuart R; Soriano, Carmen; Xiao, Xianghui; Richter, Claus-Peter

    2016-11-01

    The aim of this study was to determine if X-ray micro-computed tomography could be used to locate and characterize tissue damage caused by laser irradiation and to describe its advantages over classical histology for this application. A surgical CO 2 laser, operated in single pulse mode (100 milliseconds) at different power settings, was used to ablate different types of cadaveric animal tissues. Tissue samples were then harvested and imaged with synchrotron X-ray phase-contrast and micro-computed tomography to generate stacks of virtual sections of the tissues. Subsequently, Fiji (ImageJ) software was used to locate tissue damage, then to quantify volumes of laser ablation cones and thermal coagulation damage from 3D renderings of tissue image stacks. Visual comparisons of tissue structures in X-ray images with those visible by classic light microscopy histology were made. We demonstrated that micro-computed tomography could be used to rapidly identify areas of surgical laser ablation, vacuolization, carbonization, and thermally coagulated tissue. Quantification and comparison of the ablation crater, which represents the volume of ablated tissue, and the thermal coagulation zone volumes were performed faster than we could by classical histology. We demonstrated that these procedures can be performed on fresh hydrated and non-sectioned plastic embedded tissue. We demonstrated that the application of non-destructive micro-computed tomography to the visualization and analysis of laser induced tissue damage without tissue sectioning is possible. This will improve evaluation of new surgical lasers and their corresponding effect on tissues. Lasers Surg. Med. 48:866-877, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  7. Visual detection of particulates in x-ray images of processed meat products

    NASA Astrophysics Data System (ADS)

    Schatzki, Thomas F.; Young, Richard; Haff, Ron P.; Eye, J.; Wright, G.

    1996-08-01

    A study was conducted to test the efficacy of detecting particulate contaminants in processed meat samples by visual observation of line-scanned x-ray images. Six hundred field- collected processed-product samples were scanned at 230 cm2/s using 0.5 X 0.5-mm resolution and 50 kV, 13 mA excitation. The x-ray images were image corrected, digitally stored, and inspected off-line, using interactive image enhancement. Forty percent of the samples were spiked with added contaminants to establish the visual recognition of contaminants as a function of sample thickness (1 to 10 cm), texture of the x-ray image (smooth/textured), spike composition (wood/bone/glass), size (0.1 to 0.4 cm), and shape (splinter/round). The results were analyzed using a maximum likelihood logistic regression method. In packages less than 6 cm thick, 0.2-cm-thick bone chips were easily recognized, 0.1-cm glass splinters were recognized with some difficulty, while 0.4-cm-thick wood was generally missed. Operational feasibility in a time-constrained setting was confirmed. One half percent of the samples arriving from the field contained bone slivers > 1 cm long, 1/2% contained metallic material, while 4% contained particulates exceeding 0.3 cm in size. All of the latter appeared to be bone fragments.

  8. Synchrotron X-ray imaging of pulmonary alveoli in respiration in live intact mice.

    PubMed

    Chang, Soeun; Kwon, Namseop; Kim, Jinkyung; Kohmura, Yoshiki; Ishikawa, Tetsuya; Rhee, Chin Kook; Je, Jung Ho; Tsuda, Akira

    2015-03-04

    Despite nearly a half century of studies, it has not been fully understood how pulmonary alveoli, the elementary gas exchange units in mammalian lungs, inflate and deflate during respiration. Understanding alveolar dynamics is crucial for treating patients with pulmonary diseases. In-vivo, real-time visualization of the alveoli during respiration has been hampered by active lung movement. Previous studies have been therefore limited to alveoli at lung apices or subpleural alveoli under open thorax conditions. Here we report direct and real-time visualization of alveoli of live intact mice during respiration using tracking X-ray microscopy. Our studies, for the first time, determine the alveolar size of normal mice in respiration without positive end expiratory pressure as 58 ± 14 (mean ± s.d.) μm on average, accurately measured in the lung bases as well as the apices. Individual alveoli of normal lungs clearly show heterogeneous inflation from zero to ~25% (6.7 ± 4.7% (mean ± s.d.)) in size. The degree of inflation is higher in the lung bases (8.7 ± 4.3% (mean ± s.d.)) than in the apices (5.7 ± 3.2% (mean ± s.d.)). The fraction of the total tidal volume allocated for alveolar inflation is 34 ± 3.8% (mean ± s.e.m). This study contributes to the better understanding of alveolar dynamics and helps to develop potential treatment options for pulmonary diseases.

  9. Experimental evidence for improved neuroimaging interpretation using three-dimensional graphic models.

    PubMed

    Ruisoto, Pablo; Juanes, Juan Antonio; Contador, Israel; Mayoral, Paula; Prats-Galino, Alberto

    2012-01-01

    Three-dimensional (3D) or volumetric visualization is a useful resource for learning about the anatomy of the human brain. However, the effectiveness of 3D spatial visualization has not yet been assessed systematically. This report analyzes whether 3D volumetric visualization helps learners to identify and locate subcortical structures more precisely than classical cross-sectional images based on a two dimensional (2D) approach. Eighty participants were assigned to each experimental condition: 2D cross-sectional visualization vs. 3D volumetric visualization. Both groups were matched for age, gender, visual-spatial ability, and previous knowledge of neuroanatomy. Accuracy in identifying brain structures, execution time, and level of confidence in the response were taken as outcome measures. Moreover, interactive effects between the experimental conditions (2D vs. 3D) and factors such as level of competence (novice vs. expert), image modality (morphological and functional), and difficulty of the structures were analyzed. The percentage of correct answers (hit rate) and level of confidence in responses were significantly higher in the 3D visualization condition than in the 2D. In addition, the response time was significantly lower for the 3D visualization condition in comparison with the 2D. The interaction between the experimental condition (2D vs. 3D) and difficulty was significant, and the 3D condition facilitated the location of difficult images more than the 2D condition. 3D volumetric visualization helps to identify brain structures such as the hippocampus and amygdala, more accurately and rapidly than conventional 2D visualization. This paper discusses the implications of these results with regards to the learning process involved in neuroimaging interpretation. Copyright © 2012 American Association of Anatomists.

  10. Sensor supported pilot assistance for helicopter flight in DVE

    NASA Astrophysics Data System (ADS)

    Waanders, Tim; Münsterer, T.; Kress, M.

    2013-05-01

    Helicopter operations at low altitude are to this day only performed under VFR conditions in which safe piloting of the aircraft relies on the pilot's visual perception of the outside environment. However, there are situations in which a deterioration of visibility conditions may cause the pilot to lose important visual cues thereby increasing workload and compromising flight safety and mission effectiveness. This paper reports on a pilot assistance system for all phases of flight which is intended to: • Provide navigational support and mission management • Support landings/take-offs in unknown environment and in DVE • Enhance situational awareness in DVE • Provide obstacle and terrain surface detection and warning • Provide upload, sensor based update and download of database information for debriefing and later missions. The system comprises a digital terrain and obstacle database, tactical information, flight plan management combined with an active 3D sensor enabling the above mentioned functionalities. To support pilots during operations in DVE, an intuitive 3D/2D cueing through both head-up and head-down means is proposed to retain situational awareness. This paper further describes the system concept and will elaborate on results of simulator trials in which the functionality was evaluated by operational pilots in realistic and demanding scenarios such as a SAR mission to be performed in mountainous area under different visual conditions. The objective of the simulator trials was to evaluate the functional integration and HMI definition for the NH90 Tactical Transport Helicopter.

  11. In vivo evaluation of inter-operator reproducibility of digital dental and conventional impression techniques.

    PubMed

    Kamimura, Emi; Tanaka, Shinpei; Takaba, Masayuki; Tachi, Keita; Baba, Kazuyoshi

    2017-01-01

    The aim of this study was to evaluate and compare the inter-operator reproducibility of three-dimensional (3D) images of teeth captured by a digital impression technique to a conventional impression technique in vivo. Twelve participants with complete natural dentition were included in this study. A digital impression of the mandibular molars of these participants was made by two operators with different levels of clinical experience, 3 or 16 years, using an intra-oral scanner (Lava COS, 3M ESPE). A silicone impression also was made by the same operators using the double mix impression technique (Imprint3, 3M ESPE). Stereolithography (STL) data were directly exported from the Lava COS system, while STL data of a plaster model made from silicone impression were captured by a three-dimensional (3D) laboratory scanner (D810, 3shape). The STL datasets recorded by two different operators were compared using 3D evaluation software and superimposed using the best-fit-algorithm method (least-squares method, PolyWorks, InnovMetric Software) for each impression technique. Inter-operator reproducibility as evaluated by average discrepancies of corresponding 3D data was compared between the two techniques (Wilcoxon signed-rank test). The visual inspection of superimposed datasets revealed that discrepancies between repeated digital impression were smaller than observed with silicone impression. Confirmation was forthcoming from statistical analysis revealing significantly smaller average inter-operator reproducibility using a digital impression technique (0.014± 0.02 mm) than when using a conventional impression technique (0.023 ± 0.01 mm). The results of this in vivo study suggest that inter-operator reproducibility with a digital impression technique may be better than that of a conventional impression technique and is independent of the clinical experience of the operator.

  12. Measurement of the branching fractions for B0 -->D*-pi+ and B0 -->D*rho+

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barrera, Barbara

    Using 5.2 fb{sup -1} annihilation data recorded with the BABAR detector at the PEP-II storage ring while operating on the {Upsilon}(4S) resonance, a sample of fully reconstructed B{sup 0} decays in the hadronic modes B{sup 0} {yields} D*{sup -} {pi}{sup +} and B{sup 0} {yields} D*{sup -} {rho}{sup +} have been reconstructed. In this paper, a study of these events is reported, including preliminary measurements of the absolute branching fractions for these modes, which are found to be B(B{sup 0} {yields} D*{sup -} {pi}{sup +} = 2.9 {+-} 0.3 {+-} 0.3) x 10{sup -3} and B(B{sup 0} {yields} D*{sup -}more » {rho}{sup +}) = (11.2 {+-} 1.1 {+-} 2.5) x 10{sup -3}.« less

  13. Scalable Adaptive Graphics Environment (SAGE) Software for the Visualization of Large Data Sets on a Video Wall

    NASA Technical Reports Server (NTRS)

    Jedlovec, Gary; Srikishen, Jayanthi; Edwards, Rita; Cross, David; Welch, Jon; Smith, Matt

    2013-01-01

    The use of collaborative scientific visualization systems for the analysis, visualization, and sharing of "big data" available from new high resolution remote sensing satellite sensors or four-dimensional numerical model simulations is propelling the wider adoption of ultra-resolution tiled display walls interconnected by high speed networks. These systems require a globally connected and well-integrated operating environment that provides persistent visualization and collaboration services. This abstract and subsequent presentation describes a new collaborative visualization system installed for NASA's Shortterm Prediction Research and Transition (SPoRT) program at Marshall Space Flight Center and its use for Earth science applications. The system consists of a 3 x 4 array of 1920 x 1080 pixel thin bezel video monitors mounted on a wall in a scientific collaboration lab. The monitors are physically and virtually integrated into a 14' x 7' for video display. The display of scientific data on the video wall is controlled by a single Alienware Aurora PC with a 2nd Generation Intel Core 4.1 GHz processor, 32 GB memory, and an AMD Fire Pro W600 video card with 6 mini display port connections. Six mini display-to-dual DVI cables are used to connect the 12 individual video monitors. The open source Scalable Adaptive Graphics Environment (SAGE) windowing and media control framework, running on top of the Ubuntu 12 Linux operating system, allows several users to simultaneously control the display and storage of high resolution still and moving graphics in a variety of formats, on tiled display walls of any size. The Ubuntu operating system supports the open source Scalable Adaptive Graphics Environment (SAGE) software which provides a common environment, or framework, enabling its users to access, display and share a variety of data-intensive information. This information can be digital-cinema animations, high-resolution images, high-definition video-teleconferences, presentation slides, documents, spreadsheets or laptop screens. SAGE is cross-platform, community-driven, open-source visualization and collaboration middleware that utilizes shared national and international cyberinfrastructure for the advancement of scientific research and education.

  14. Scalable Adaptive Graphics Environment (SAGE) Software for the Visualization of Large Data Sets on a Video Wall

    NASA Astrophysics Data System (ADS)

    Jedlovec, G.; Srikishen, J.; Edwards, R.; Cross, D.; Welch, J. D.; Smith, M. R.

    2013-12-01

    The use of collaborative scientific visualization systems for the analysis, visualization, and sharing of 'big data' available from new high resolution remote sensing satellite sensors or four-dimensional numerical model simulations is propelling the wider adoption of ultra-resolution tiled display walls interconnected by high speed networks. These systems require a globally connected and well-integrated operating environment that provides persistent visualization and collaboration services. This abstract and subsequent presentation describes a new collaborative visualization system installed for NASA's Short-term Prediction Research and Transition (SPoRT) program at Marshall Space Flight Center and its use for Earth science applications. The system consists of a 3 x 4 array of 1920 x 1080 pixel thin bezel video monitors mounted on a wall in a scientific collaboration lab. The monitors are physically and virtually integrated into a 14' x 7' for video display. The display of scientific data on the video wall is controlled by a single Alienware Aurora PC with a 2nd Generation Intel Core 4.1 GHz processor, 32 GB memory, and an AMD Fire Pro W600 video card with 6 mini display port connections. Six mini display-to-dual DVI cables are used to connect the 12 individual video monitors. The open source Scalable Adaptive Graphics Environment (SAGE) windowing and media control framework, running on top of the Ubuntu 12 Linux operating system, allows several users to simultaneously control the display and storage of high resolution still and moving graphics in a variety of formats, on tiled display walls of any size. The Ubuntu operating system supports the open source Scalable Adaptive Graphics Environment (SAGE) software which provides a common environment, or framework, enabling its users to access, display and share a variety of data-intensive information. This information can be digital-cinema animations, high-resolution images, high-definition video-teleconferences, presentation slides, documents, spreadsheets or laptop screens. SAGE is cross-platform, community-driven, open-source visualization and collaboration middleware that utilizes shared national and international cyberinfrastructure for the advancement of scientific research and education.

  15. PRK vs LASEK vs Epi-LASIK: a comparison of corneal haze, postoperative pain and visual recovery in moderate to high myopia.

    PubMed

    Reilly, C D; Panday, V; Lazos, V; Mittelstaedt, B R

    2010-01-01

    The field of refractive surgery continues to evolve amid continued concerns as to which surgical technique minimizes the risk of inducing ectasia. To compare clinical outcomes between PRK, LASEK and Epi-LASIK in moderately to highly myopic eyes (-4.00 D to -8.00 D). A retrospective chart review of 100 PRK eyes, 100 LASEK eyes (with alcohol) and 97 Epi-LASIK eyes was performed. Post-operative pain, uncorrected visual acuity, and corneal haze data was recorded and analyzed at post-op days 1, 4 and 7 and at post-op months 1, 3, 6 and 12. In all groups surgical corrections ranged from -4.00 D to -8.00 D. There was less pain associated with the epi-LASIK procedure especially early (post-op days 1 and 4). Visual recovery was superior within the PRK group during the first post-operative week but by post-op week 4 all three were equal. Haze scores were similar but a trend for less haze was demonstrated with epi-LASIK at 6 and 12 months. Epi-LASIK has a slight advantage over PRK and LASEK early on in the post-op course with regards to pain. Visual recovery is similar by 4 weeks and is better with PRK early. In addition, epi-LASIK trends toward less significant haze. © Nepal Ophthalmic Society.

  16. Experimental and Theoretical Study on Cavitation Inception and Bubbly Flow Dynamics. Part 1. Design, Development and Operation of a Cavitation Susceptibility Meter. Part 2. Linearized Dynamics of Bubbly and Cavitating Flows with Bubble Dynamics Effects.

    DTIC Science & Technology

    1987-05-01

    condition at the wall: v( x , y,.)/Uo = dri/dx results in the following bound- ary condition for R( x , y): 3 (OR) 2 1 [2S _ q] d2r (1 0) y X2 ; -PGo __ 2P d...i - X - 30 bar (downward triangles) for T = 20 *C (water temperature) and Dt = 1 mm (throat diameter). Figure 2.9. Bubble detection length L! necessary...diffuser of the venturi of Fig. 2.14 without incurring in laminar separation as a function of the distance x from the diffuser inlet. Figure 3.1. Schematic

  17. Distributed augmented reality with 3-D lung dynamics--a planning tool concept.

    PubMed

    Hamza-Lup, Felix G; Santhanam, Anand P; Imielińska, Celina; Meeks, Sanford L; Rolland, Jannick P

    2007-01-01

    Augmented reality (AR) systems add visual information to the world by using advanced display techniques. The advances in miniaturization and reduced hardware costs make some of these systems feasible for applications in a wide set of fields. We present a potential component of the cyber infrastructure for the operating room of the future: a distributed AR-based software-hardware system that allows real-time visualization of three-dimensional (3-D) lung dynamics superimposed directly on the patient's body. Several emergency events (e.g., closed and tension pneumothorax) and surgical procedures related to lung (e.g., lung transplantation, lung volume reduction surgery, surgical treatment of lung infections, lung cancer surgery) could benefit from the proposed prototype.

  18. High Performance GPU-Based Fourier Volume Rendering.

    PubMed

    Abdellah, Marwan; Eldeib, Ayman; Sharawi, Amr

    2015-01-01

    Fourier volume rendering (FVR) is a significant visualization technique that has been used widely in digital radiography. As a result of its (N (2)log⁡N) time complexity, it provides a faster alternative to spatial domain volume rendering algorithms that are (N (3)) computationally complex. Relying on the Fourier projection-slice theorem, this technique operates on the spectral representation of a 3D volume instead of processing its spatial representation to generate attenuation-only projections that look like X-ray radiographs. Due to the rapid evolution of its underlying architecture, the graphics processing unit (GPU) became an attractive competent platform that can deliver giant computational raw power compared to the central processing unit (CPU) on a per-dollar-basis. The introduction of the compute unified device architecture (CUDA) technology enables embarrassingly-parallel algorithms to run efficiently on CUDA-capable GPU architectures. In this work, a high performance GPU-accelerated implementation of the FVR pipeline on CUDA-enabled GPUs is presented. This proposed implementation can achieve a speed-up of 117x compared to a single-threaded hybrid implementation that uses the CPU and GPU together by taking advantage of executing the rendering pipeline entirely on recent GPU architectures.

  19. 2D/3D Visual Tracker for Rover Mast

    NASA Technical Reports Server (NTRS)

    Bajracharya, Max; Madison, Richard W.; Nesnas, Issa A.; Bandari, Esfandiar; Kunz, Clayton; Deans, Matt; Bualat, Maria

    2006-01-01

    A visual-tracker computer program controls an articulated mast on a Mars rover to keep a designated feature (a target) in view while the rover drives toward the target, avoiding obstacles. Several prior visual-tracker programs have been tested on rover platforms; most require very small and well-estimated motion between consecutive image frames a requirement that is not realistic for a rover on rough terrain. The present visual-tracker program is designed to handle large image motions that lead to significant changes in feature geometry and photometry between frames. When a point is selected in one of the images acquired from stereoscopic cameras on the mast, a stereo triangulation algorithm computes a three-dimensional (3D) location for the target. As the rover moves, its body-mounted cameras feed images to a visual-odometry algorithm, which tracks two-dimensional (2D) corner features and computes their old and new 3D locations. The algorithm rejects points, the 3D motions of which are inconsistent with a rigid-world constraint, and then computes the apparent change in the rover pose (i.e., translation and rotation). The mast pan and tilt angles needed to keep the target centered in the field-of-view of the cameras (thereby minimizing the area over which the 2D-tracking algorithm must operate) are computed from the estimated change in the rover pose, the 3D position of the target feature, and a model of kinematics of the mast. If the motion between the consecutive frames is still large (i.e., 3D tracking was unsuccessful), an adaptive view-based matching technique is applied to the new image. This technique uses correlation-based template matching, in which a feature template is scaled by the ratio between the depth in the original template and the depth of pixels in the new image. This is repeated over the entire search window and the best correlation results indicate the appropriate match. The program could be a core for building application programs for systems that require coordination of vision and robotic motion.

  20. N=2 Minimal Conformal Field Theories and Matrix Bifactorisations of x d

    NASA Astrophysics Data System (ADS)

    Davydov, Alexei; Camacho, Ana Ros; Runkel, Ingo

    2018-01-01

    We establish an action of the representations of N = 2-superconformal symmetry on the category of matrix factorisations of the potentials x d and x d - y d , for d odd. More precisely we prove a tensor equivalence between (a) the category of Neveu-Schwarz-type representations of the N = 2 minimal super vertex operator algebra at central charge 3-6/d, and (b) a full subcategory of graded matrix factorisations of the potential x d - y d . The subcategory in (b) is given by permutation-type matrix factorisations with consecutive index sets. The physical motivation for this result is the Landau-Ginzburg/conformal field theory correspondence, where it amounts to the equivalence of a subset of defects on both sides of the correspondence. Our work builds on results by Brunner and Roggenkamp [BR], where an isomorphism of fusion rules was established.

  1. [Therapy relevant imaging in modern surgical treatment of arthrosis of the shoulder: interesting facts for orthopedic surgeons].

    PubMed

    Krifter, R M; Zweiger, C; Lick-Schiffer, W; Mattiassich, G; Schüller-Weidekamm, C; Radl, R

    2013-03-01

    Imaging for shoulder surgery varies a lot nowadays. Advantages and disadvantages of possible imaging methods according to the pathology and treatment options are described. Digital projection radiography in 3 planes, ultrasonography, MRI, CT scanning and scintigrams. Special axial view to visualize the glenoid situation, as well as 3-D CT scanning for larger defects and classification. Imaging of the glenoid situation, the version and erosion in axial view x-ray is mandatory to plan and control glenoid replacement. Useful application of imaging methods for the daily routine of orthopedic surgeons. Digital 3 plane x-ray imaging in arthroplasty surgery is the minimum requirement. For rotator cuff lesions ultrasonography is good. In order to gain information on fatty infiltration of rotator muscles MRI is needed as well as for intra-articular lesions. For bony defects CT and reconstruction 3-D are recommended.

  2. Virtual reality in rhinology-a new dimension of clinical experience.

    PubMed

    Klapan, Ivica; Raos, Pero; Galeta, Tomislav; Kubat, Goranka

    2016-07-01

    There is often a need to more precisely identify the extent of pathology and the fine elements of intracranial anatomic features during the diagnostic process and during many operations in the nose, sinus, orbit, and skull base region. In two case reports, we describe the methods used in the diagnostic workup and surgical therapy in the nose and paranasal sinus region. Besides baseline x-ray, multislice computed tomography, and magnetic resonance imaging, operative field imaging was performed via a rapid prototyping model, virtual endoscopy, and 3-D imaging. Different head tissues were visualized in different colors, showing their anatomic interrelations and the extent of pathologic tissue within the operative field. This approach has not yet been used as a standard preoperative or intraoperative procedure in otorhinolaryngology. In this way, we tried to understand the new, visualized "world of anatomic relations within the patient's head" by creating an impression of perception (virtual perception) of the given position of all elements in a particular anatomic region of the head, which does not exist in the real world (virtual world). This approach was aimed at upgrading the diagnostic workup and surgical therapy by ensuring a faster, safer and, above all, simpler operative procedure. In conclusion, any ENT specialist can provide virtual reality support in implementing surgical procedures, with additional control of risks and within the limits of normal tissue, without additional trauma to the surrounding tissue in the anatomic region. At the same time, the virtual reality support provides an impression of the virtual world as the specialist navigates through it and manipulates virtual objects.

  3. Utilization of high resolution computed tomography to visualize the three dimensional structure and function of plant vasculature

    USDA-ARS?s Scientific Manuscript database

    High resolution x-ray computed tomography (HRCT) is a non-destructive diagnostic imaging technique with sub-micron resolution capability that is now being used to evaluate the structure and function of plant xylem network in three dimensions (3D). HRCT imaging is based on the same principles as medi...

  4. In Situ Three-Dimensional Reciprocal-Space Mapping of Diffuse Scattering Intensity Distribution and Data Analysis for Precursor Phenomenon in Shape-Memory Alloy

    NASA Astrophysics Data System (ADS)

    Cheng, Tian-Le; Ma, Fengde D.; Zhou, Jie E.; Jennings, Guy; Ren, Yang; Jin, Yongmei M.; Wang, Yu U.

    2012-01-01

    Diffuse scattering contains rich information on various structural disorders, thus providing a useful means to study the nanoscale structural deviations from the average crystal structures determined by Bragg peak analysis. Extraction of maximal information from diffuse scattering requires concerted efforts in high-quality three-dimensional (3D) data measurement, quantitative data analysis and visualization, theoretical interpretation, and computer simulations. Such an endeavor is undertaken to study the correlated dynamic atomic position fluctuations caused by thermal vibrations (phonons) in precursor state of shape-memory alloys. High-quality 3D diffuse scattering intensity data around representative Bragg peaks are collected by using in situ high-energy synchrotron x-ray diffraction and two-dimensional digital x-ray detector (image plate). Computational algorithms and codes are developed to construct the 3D reciprocal-space map of diffuse scattering intensity distribution from the measured data, which are further visualized and quantitatively analyzed to reveal in situ physical behaviors. Diffuse scattering intensity distribution is explicitly formulated in terms of atomic position fluctuations to interpret the experimental observations and identify the most relevant physical mechanisms, which help set up reduced structural models with minimal parameters to be efficiently determined by computer simulations. Such combined procedures are demonstrated by a study of phonon softening phenomenon in precursor state and premartensitic transformation of Ni-Mn-Ga shape-memory alloy.

  5. 3D printing of preclinical X-ray computed tomographic data sets.

    PubMed

    Doney, Evan; Krumdick, Lauren A; Diener, Justin M; Wathen, Connor A; Chapman, Sarah E; Stamile, Brian; Scott, Jeremiah E; Ravosa, Matthew J; Van Avermaete, Tony; Leevy, W Matthew

    2013-03-22

    Three-dimensional printing allows for the production of highly detailed objects through a process known as additive manufacturing. Traditional, mold-injection methods to create models or parts have several limitations, the most important of which is a difficulty in making highly complex products in a timely, cost-effective manner.(1) However, gradual improvements in three-dimensional printing technology have resulted in both high-end and economy instruments that are now available for the facile production of customized models.(2) These printers have the ability to extrude high-resolution objects with enough detail to accurately represent in vivo images generated from a preclinical X-ray CT scanner. With proper data collection, surface rendering, and stereolithographic editing, it is now possible and inexpensive to rapidly produce detailed skeletal and soft tissue structures from X-ray CT data. Even in the early stages of development, the anatomical models produced by three-dimensional printing appeal to both educators and researchers who can utilize the technology to improve visualization proficiency. (3, 4) The real benefits of this method result from the tangible experience a researcher can have with data that cannot be adequately conveyed through a computer screen. The translation of pre-clinical 3D data to a physical object that is an exact copy of the test subject is a powerful tool for visualization and communication, especially for relating imaging research to students, or those in other fields. Here, we provide a detailed method for printing plastic models of bone and organ structures derived from X-ray CT scans utilizing an Albira X-ray CT system in conjunction with PMOD, ImageJ, Meshlab, Netfabb, and ReplicatorG software packages.

  6. 3D visualization of subcellular structures of Schizosaccharomyces pombe by hard X-ray tomography.

    PubMed

    Yang, Y; Li, W; Liu, G; Zhang, X; Chen, J; Wu, W; Guan, Y; Xiong, Y; Tian, Y; Wu, Z

    2010-10-01

    Cellular structures of the fission yeast, Schizosaccharomyces pombe, were examined by using hard X-ray tomography. Since cells are nearly transparent to hard X-rays, Zernike phase contrast and heavy metal staining were introduced to improve image contrast. Through using such methods, images taken at 8 keV displayed sufficient contrast for observing cellular structures. The cell wall, the intracellular organelles and the entire structural organization of the whole cells were visualized in three-dimensional at a resolution better than 100 nm. Comparison between phase contrast and absorption contrast was also made, indicating the obvious advantage of phase contrast for cellular imaging at this energy. Our results demonstrate that hard X-ray tomography with Zernike phase contrast is suitable for cellular imaging. Its unique abilities make it have potential to become a useful tool for revealing structural information from cells, especially thick eukaryotic cells. © 2010 The Authors Journal compilation © 2010 The Royal Microscopical Society.

  7. PyEPL: a cross-platform experiment-programming library.

    PubMed

    Geller, Aaron S; Schlefer, Ian K; Sederberg, Per B; Jacobs, Joshua; Kahana, Michael J

    2007-11-01

    PyEPL (the Python Experiment-Programming Library) is a Python library which allows cross-platform and object-oriented coding of behavioral experiments. It provides functions for displaying text and images onscreen, as well as playing and recording sound, and is capable of rendering 3-D virtual environments forspatial-navigation tasks. It is currently tested for Mac OS X and Linux. It interfaces with Activewire USB cards (on Mac OS X) and the parallel port (on Linux) for synchronization of experimental events with physiological recordings. In this article, we first present two sample programs which illustrate core PyEPL features. The examples demonstrate visual stimulus presentation, keyboard input, and simulation and exploration of a simple 3-D environment. We then describe the components and strategies used in implementing PyEPL.

  8. PyEPL: A cross-platform experiment-programming library

    PubMed Central

    Geller, Aaron S.; Schleifer, Ian K.; Sederberg, Per B.; Jacobs, Joshua; Kahana, Michael J.

    2009-01-01

    PyEPL (the Python Experiment-Programming Library) is a Python library which allows cross-platform and object-oriented coding of behavioral experiments. It provides functions for displaying text and images onscreen, as well as playing and recording sound, and is capable of rendering 3-D virtual environments for spatial-navigation tasks. It is currently tested for Mac OS X and Linux. It interfaces with Activewire USB cards (on Mac OS X) and the parallel port (on Linux) for synchronization of experimental events with physiological recordings. In this article, we first present two sample programs which illustrate core PyEPL features. The examples demonstrate visual stimulus presentation, keyboard input, and simulation and exploration of a simple 3-D environment. We then describe the components and strategies used in implementing PyEPL. PMID:18183912

  9. Virtual reality and 3D visualizations in heart surgery education.

    PubMed

    Friedl, Reinhard; Preisack, Melitta B; Klas, Wolfgang; Rose, Thomas; Stracke, Sylvia; Quast, Klaus J; Hannekum, Andreas; Gödje, Oliver

    2002-01-01

    Computer assisted teaching plays an increasing role in surgical education. The presented paper describes the development of virtual reality (VR) and 3D visualizations for educational purposes concerning aortocoronary bypass grafting and their prototypical implementation into a database-driven and internet-based educational system in heart surgery. A multimedia storyboard has been written and digital video has been encoded. Understanding of these videos was not always satisfying; therefore, additional 3D and VR visualizations have been modelled as VRML, QuickTime, QuickTime Virtual Reality and MPEG-1 applications. An authoring process in terms of integration and orchestration of different multimedia components to educational units has been started. A virtual model of the heart has been designed. It is highly interactive and the user is able to rotate it, move it, zoom in for details or even fly through. It can be explored during the cardiac cycle and a transparency mode demonstrates coronary arteries, movement of the heart valves, and simultaneous blood-flow. Myocardial ischemia and the effect of an IMA-Graft on myocardial perfusion is simulated. Coronary artery stenoses and bypass-grafts can be interactively added. 3D models of anastomotique techniques and closed thrombendarterectomy have been developed. Different visualizations have been prototypically implemented into a teaching application about operative techniques. Interactive virtual reality and 3D teaching applications can be used and distributed via the World Wide Web and have the power to describe surgical anatomy and principles of surgical techniques, where temporal and spatial events play an important role, in a way superior to traditional teaching methods.

  10. Tetrahedral Hohlraum Visualization and Pointings

    NASA Astrophysics Data System (ADS)

    Klare, K. A.; Wallace, J. M.; Drake, D.

    1997-11-01

    In designing experiments for Omega, the tetrahedral hohlraum (a sphere with four holes) can make full use of all 60 beams. There are some complications: the beams must clear the laser entrance hole (LEH), must miss a central capsule, absolutely must not go out the other LEHs, and should distribute in the interior of the hohlraum to maximize the uniformity of irradiation on the capsule while keeping reasonable laser spot sizes. We created a 15-offset coordinate system with which an IDL program computes clearances, writes a file for QuickDraw 3D (QD3D) visualization, and writes input for the viewfactor code RAYNA IV. Visualizing and adjusting the parameters by eye gave more reliable results than computer optimization. QD3D images permitted quick live rotations to determine offsets. The clearances obtained insured safe operation and good physics. The viewfactor code computes the initial irradiation of the hohlraum and capsule or of a uniform hohlraum source with the loss through the four LEHs and shows a high degree of uniformity with both, better for lasers because this deposits more energy near the LEHs to compensate for the holes.

  11. Recent improvements in SPE3D: a VR-based surgery planning environment

    NASA Astrophysics Data System (ADS)

    Witkowski, Marcin; Sitnik, Robert; Verdonschot, Nico

    2014-02-01

    SPE3D is a surgery planning environment developed within TLEMsafe project [1] (funded by the European Commission FP7). It enables the operator to plan a surgical procedure on the customized musculoskeletal (MS) model of the patient's lower limbs, send the modified model to the biomechanical analysis module, and export the scenario's parameters to the surgical navigation system. The personalized patient-specific three-dimensional (3-D) MS model is registered with 3-D MRI dataset of lower limbs and the two modalities may be visualized simultaneously. Apart from main planes, any arbitrary MRI cross-section can be rendered on the 3-D MS model in real time. The interface provides tools for: bone cutting, manipulating and removal, repositioning muscle insertion points, modifying muscle force, removing muscles and placing implants stored in the implant library. SPE3D supports stereoscopic viewing as well as natural inspection/manipulation with use of haptic devices. Alternatively, it may be controlled with use of a standard computer keyboard, mouse and 2D display or a touch screen (e.g. in an operating room). The interface may be utilized in two main fields. Experienced surgeons may use it to simulate their operative plans and prepare input data for a surgical navigation system while student or novice surgeons can use it for training.

  12. DSSR-enhanced visualization of nucleic acid structures in Jmol.

    PubMed

    Hanson, Robert M; Lu, Xiang-Jun

    2017-07-03

    Sophisticated and interactive visualizations are essential for making sense of the intricate 3D structures of macromolecules. For proteins, secondary structural components are routinely featured in molecular graphics visualizations. However, the field of RNA structural bioinformatics is still lagging behind; for example, current molecular graphics tools lack built-in support even for base pairs, double helices, or hairpin loops. DSSR (Dissecting the Spatial Structure of RNA) is an integrated and automated command-line tool for the analysis and annotation of RNA tertiary structures. It calculates a comprehensive and unique set of features for characterizing RNA, as well as DNA structures. Jmol is a widely used, open-source Java viewer for 3D structures, with a powerful scripting language. JSmol, its reincarnation based on native JavaScript, has a predominant position in the post Java-applet era for web-based visualization of molecular structures. The DSSR-Jmol integration presented here makes salient features of DSSR readily accessible, either via the Java-based Jmol application itself, or its HTML5-based equivalent, JSmol. The DSSR web service accepts 3D coordinate files (in mmCIF or PDB format) initiated from a Jmol or JSmol session and returns DSSR-derived structural features in JSON format. This seamless combination of DSSR and Jmol/JSmol brings the molecular graphics of 3D RNA structures to a similar level as that for proteins, and enables a much deeper analysis of structural characteristics. It fills a gap in RNA structural bioinformatics, and is freely accessible (via the Jmol application or the JSmol-based website http://jmol.x3dna.org). © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  13. Comparative case study between D3 and highcharts on lustre data visualization

    NASA Astrophysics Data System (ADS)

    ElTayeby, Omar; John, Dwayne; Patel, Pragnesh; Simmerman, Scott

    2013-12-01

    One of the challenging tasks in visual analytics is to target clustered time-series data sets, since it is important for data analysts to discover patterns changing over time while keeping their focus on particular subsets. In order to leverage the humans ability to quickly visually perceive these patterns, multivariate features should be implemented according to the attributes available. However, a comparative case study has been done using JavaScript libraries to demonstrate the differences in capabilities of using them. A web-based application to monitor the Lustre file system for the systems administrators and the operation teams has been developed using D3 and Highcharts. Lustre file systems are responsible of managing Remote Procedure Calls (RPCs) which include input output (I/O) requests between clients and Object Storage Targets (OSTs). The objective of this application is to provide time-series visuals of these calls and storage patterns of users on Kraken, a University of Tennessee High Performance Computing (HPC) resource in Oak Ridge National Laboratory (ORNL).

  14. Validation of digital elevation models (DEMs) and comparison of geomorphic metrics on the southern Central Andean Plateau

    NASA Astrophysics Data System (ADS)

    Purinton, Benjamin; Bookhagen, Bodo

    2017-04-01

    In this study, we validate and compare elevation accuracy and geomorphic metrics of satellite-derived digital elevation models (DEMs) on the southern Central Andean Plateau. The plateau has an average elevation of 3.7 km and is characterized by diverse topography and relief, lack of vegetation, and clear skies that create ideal conditions for remote sensing. At 30 m resolution, SRTM-C, ASTER GDEM2, stacked ASTER L1A stereopair DEM, ALOS World 3D, and TanDEM-X have been analyzed. The higher-resolution datasets include 12 m TanDEM-X, 10 m single-CoSSC TerraSAR-X/TanDEM-X DEMs, and 5 m ALOS World 3D. These DEMs are state of the art for optical (ASTER and ALOS) and radar (SRTM-C and TanDEM-X) spaceborne sensors. We assessed vertical accuracy by comparing standard deviations of the DEM elevation versus 307 509 differential GPS measurements across 4000 m of elevation. For the 30 m DEMs, the ASTER datasets had the highest vertical standard deviation at > 6.5 m, whereas the SRTM-C, ALOS World 3D, and TanDEM-X were all < 3.5 m. Higher-resolution DEMs generally had lower uncertainty, with both the 12 m TanDEM-X and 5 m ALOS World 3D having < 2 m vertical standard deviation. Analysis of vertical uncertainty with respect to terrain elevation, slope, and aspect revealed the low uncertainty across these attributes for SRTM-C (30 m), TanDEM-X (12-30 m), and ALOS World 3D (5-30 m). Single-CoSSC TerraSAR-X/TanDEM-X 10 m DEMs and the 30 m ASTER GDEM2 displayed slight aspect biases, which were removed in their stacked counterparts (TanDEM-X and ASTER Stack). Based on low vertical standard deviations and visual inspection alongside optical satellite data, we selected the 30 m SRTM-C, 12-30 m TanDEM-X, 10 m single-CoSSC TerraSAR-X/TanDEM-X, and 5 m ALOS World 3D for geomorphic metric comparison in a 66 km2 catchment with a distinct river knickpoint. Consistent m/n values were found using chi plot channel profile analysis, regardless of DEM type and spatial resolution. Slope, curvature, and drainage area were calculated and plotting schemes were used to assess basin-wide differences in the hillslope-to-valley transition related to the knickpoint. While slope and hillslope length measurements vary little between datasets, curvature displays higher magnitude measurements with fining resolution. This is especially true for the optical 5 m ALOS World 3D DEM, which demonstrated high-frequency noise in 2-8 pixel steps through a Fourier frequency analysis. The improvements in accurate space-radar DEMs (e.g., TanDEM-X) for geomorphometry are promising, but airborne or terrestrial data are still necessary for meter-scale analysis.

  15. Lifting q-difference operators for Askey-Wilson polynomials and their weight function

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Atakishiyeva, M. K.; Atakishiyev, N. M., E-mail: natig_atakishiyev@hotmail.com

    2011-06-15

    We determine an explicit form of a q-difference operator that transforms the continuous q-Hermite polynomials H{sub n}(x | q) of Rogers into the Askey-Wilson polynomials p{sub n}(x; a, b, c, d | q) on the top level in the Askey q-scheme. This operator represents a special convolution-type product of four one-parameter q-difference operators of the form {epsilon}{sub q}(c{sub q}D{sub q}) (where c{sub q} are some constants), defined as Exton's q-exponential function {epsilon}{sub q}(z) in terms of the Askey-Wilson divided q-difference operator D{sub q}. We also determine another q-difference operator that lifts the orthogonality weight function for the continuous q-Hermite polynomialsH{submore » n}(x | q) up to the weight function, associated with the Askey-Wilson polynomials p{sub n}(x; a, b, c, d | q).« less

  16. MorphoGraphX: A platform for quantifying morphogenesis in 4D

    PubMed Central

    Barbier de Reuille, Pierre; Routier-Kierzkowska, Anne-Lise; Kierzkowski, Daniel; Bassel, George W; Schüpbach, Thierry; Tauriello, Gerardo; Bajpai, Namrata; Strauss, Sören; Weber, Alain; Kiss, Annamaria; Burian, Agata; Hofhuis, Hugo; Sapala, Aleksandra; Lipowczan, Marcin; Heimlicher, Maria B; Robinson, Sarah; Bayer, Emmanuelle M; Basler, Konrad; Koumoutsakos, Petros; Roeder, Adrienne HK; Aegerter-Wilmsen, Tinri; Nakayama, Naomi; Tsiantis, Miltos; Hay, Angela; Kwiatkowska, Dorota; Xenarios, Ioannis; Kuhlemeier, Cris; Smith, Richard S

    2015-01-01

    Morphogenesis emerges from complex multiscale interactions between genetic and mechanical processes. To understand these processes, the evolution of cell shape, proliferation and gene expression must be quantified. This quantification is usually performed either in full 3D, which is computationally expensive and technically challenging, or on 2D planar projections, which introduces geometrical artifacts on highly curved organs. Here we present MorphoGraphX (www.MorphoGraphX.org), a software that bridges this gap by working directly with curved surface images extracted from 3D data. In addition to traditional 3D image analysis, we have developed algorithms to operate on curved surfaces, such as cell segmentation, lineage tracking and fluorescence signal quantification. The software's modular design makes it easy to include existing libraries, or to implement new algorithms. Cell geometries extracted with MorphoGraphX can be exported and used as templates for simulation models, providing a powerful platform to investigate the interactions between shape, genes and growth. DOI: http://dx.doi.org/10.7554/eLife.05864.001 PMID:25946108

  17. Event Display for the Visualization of CMS Events

    NASA Astrophysics Data System (ADS)

    Bauerdick, L. A. T.; Eulisse, G.; Jones, C. D.; Kovalskyi, D.; McCauley, T.; Mrak Tadel, A.; Muelmenstaedt, J.; Osborne, I.; Tadel, M.; Tu, Y.; Yagil, A.

    2011-12-01

    During the last year the CMS experiment engaged in consolidation of its existing event display programs. The core of the new system is based on the Fireworks event display program which was by-design directly integrated with the CMS Event Data Model (EDM) and the light version of the software framework (FWLite). The Event Visualization Environment (EVE) of the ROOT framework is used to manage a consistent set of 3D and 2D views, selection, user-feedback and user-interaction with the graphics windows; several EVE components were developed by CMS in collaboration with the ROOT project. In event display operation simple plugins are registered into the system to perform conversion from EDM collections into their visual representations which are then managed by the application. Full event navigation and filtering as well as collection-level filtering is supported. The same data-extraction principle can also be applied when Fireworks will eventually operate as a service within the full software framework.

  18. The role of 3-D interactive visualization in blind surveys of H I in galaxies

    NASA Astrophysics Data System (ADS)

    Punzo, D.; van der Hulst, J. M.; Roerdink, J. B. T. M.; Oosterloo, T. A.; Ramatsoku, M.; Verheijen, M. A. W.

    2015-09-01

    Upcoming H I surveys will deliver large datasets, and automated processing using the full 3-D information (two positional dimensions and one spectral dimension) to find and characterize H I objects is imperative. In this context, visualization is an essential tool for enabling qualitative and quantitative human control on an automated source finding and analysis pipeline. We discuss how Visual Analytics, the combination of automated data processing and human reasoning, creativity and intuition, supported by interactive visualization, enables flexible and fast interaction with the 3-D data, helping the astronomer to deal with the analysis of complex sources. 3-D visualization, coupled to modeling, provides additional capabilities helping the discovery and analysis of subtle structures in the 3-D domain. The requirements for a fully interactive visualization tool are: coupled 1-D/2-D/3-D visualization, quantitative and comparative capabilities, combined with supervised semi-automated analysis. Moreover, the source code must have the following characteristics for enabling collaborative work: open, modular, well documented, and well maintained. We review four state of-the-art, 3-D visualization packages assessing their capabilities and feasibility for use in the case of 3-D astronomical data.

  19. Developing mobile- and BIM-based integrated visual facility maintenance management system.

    PubMed

    Lin, Yu-Cheng; Su, Yu-Chih

    2013-01-01

    Facility maintenance management (FMM) has become an important topic for research on the operation phase of the construction life cycle. Managing FMM effectively is extremely difficult owing to various factors and environments. One of the difficulties is the performance of 2D graphics when depicting maintenance service. Building information modeling (BIM) uses precise geometry and relevant data to support the maintenance service of facilities depicted in 3D object-oriented CAD. This paper proposes a new and practical methodology with application to FMM using BIM technology. Using BIM technology, this study proposes a BIM-based facility maintenance management (BIMFMM) system for maintenance staff in the operation and maintenance phase. The BIMFMM system is then applied in selected case study of a commercial building project in Taiwan to verify the proposed methodology and demonstrate its effectiveness in FMM practice. Using the BIMFMM system, maintenance staff can access and review 3D BIM models for updating related maintenance records in a digital format. Moreover, this study presents a generic system architecture and its implementation. The combined results demonstrate that a BIMFMM-like system can be an effective visual FMM tool.

  20. NASA's Hubble Universe in 3-D

    NASA Image and Video Library

    2017-12-08

    This image depicts a vast canyon of dust and gas in the Orion Nebula from a 3-D computer model based on observations by NASA's Hubble Space Telescope and created by science visualization specialists at the Space Telescope Science Institute (STScI) in Baltimore, Md. A 3-D visualization of this model takes viewers on an amazing four-minute voyage through the 15-light-year-wide canyon. Credit: NASA, G. Bacon, L. Frattare, Z. Levay, and F. Summers (STScI/AURA) Go here to learn more about Hubble 3D: www.nasa.gov/topics/universe/features/hubble_imax_premier... or www.imax.com/hubble/ Take an exhilarating ride through the Orion Nebula, a vast star-making factory 1,500 light-years away. Swoop through Orion's giant canyon of gas and dust. Fly past behemoth stars whose brilliant light illuminates and energizes the entire cloudy region. Zoom by dusty tadpole-shaped objects that are fledgling solar systems. This virtual space journey isn't the latest video game but one of several groundbreaking astronomy visualizations created by specialists at the Space Telescope Science Institute (STScI) in Baltimore, the science operations center for NASA's Hubble Space Telescope. The cinematic space odysseys are part of the new Imax film "Hubble 3D," which opens today at select Imax theaters worldwide. The 43-minute movie chronicles the 20-year life of Hubble and includes highlights from the May 2009 servicing mission to the Earth-orbiting observatory, with footage taken by the astronauts. The giant-screen film showcases some of Hubble's breathtaking iconic pictures, such as the Eagle Nebula's "Pillars of Creation," as well as stunning views taken by the newly installed Wide Field Camera 3. While Hubble pictures of celestial objects are awe-inspiring, they are flat 2-D photographs. For this film, those 2-D images have been converted into 3-D environments, giving the audience the impression they are space travelers taking a tour of Hubble's most popular targets. "A large-format movie is a truly immersive experience," says Frank Summers, an STScI astronomer and science visualization specialist who led the team that developed the movie visualizations. The team labored for nine months, working on four visualization sequences that comprise about 12 minutes of the movie. "Seeing these Hubble images in 3-D, you feel like you are flying through space and not just looking at picture postcards," Summers continued. "The spacescapes are all based on Hubble images and data, though some artistic license is necessary to produce the full depth of field needed for 3-D." The most ambitious sequence is a four-minute voyage through the Orion Nebula's gas-and-dust canyon, about 15 light-years across. During the ride, viewers will see bright and dark, gaseous clouds; thousands of stars, including a grouping of bright, hefty stars called the Trapezium; and embryonic planetary systems. The tour ends with a detailed look at a young circumstellar disk, which is much like the structure from which our solar system formed 4.5 billion years ago. Based on a Hubble image of Orion released in 2006, the visualization was a collaborative effort between science visualization specialists at STScI, including Greg Bacon, who sculpted the Orion Nebula digital model, with input from STScI astronomer Massimo Roberto; the National Center for Supercomputing Applications at the University of Illinois at Urbana-Champaign; and the Spitzer Science Center at the California Institute of Technology in Pasadena. For some of the sequences, STScI imaging specialists developed new techniques for transforming the 2-D Hubble images into 3-D. STScI image processing specialists Lisa Frattare and Zolt Levay, for example, created methods of splitting a giant gaseous pillar in the Carina Nebula into multiple layers to produce a 3-D effect, giving the structure depth. The Carina Nebula is a nursery for baby stars. Frattare painstakingly removed the thousands of stars in the image so that Levay could separate the gaseous layers on the isolated Carina pillar. Frattare then replaced the stars into both foreground and background layers to complete the 3-D model. For added effect, the same separation was done for both visible and infrared Hubble images, allowing the film to cross-fade between wavelength views in 3-D. In another sequence viewers fly into a field of 170,000 stars in the giant star cluster Omega Centauri. STScI astronomer Jay Anderson used his stellar database to create a synthetic star field in 3-D that matches recent razor-sharp Hubble photos. The film's final four-minute sequence takes viewers on a voyage from our Milky Way Galaxy past many of Hubble's best galaxy shots and deep into space. Some 15,000 galaxies from Hubble's deepest surveys stretch billions of light-years across the universe in a 3-D sequence created by STScI astronomers and visualizers. The view dissolves into a cobweb that traces the universe's large-scale structure, the backbone from which galaxies were born. In addition to creating visualizations, STScI's education group also provided guidance on the "Hubble 3D" Educator Guide, which includes standards-based lesson plans and activities about Hubble and its mission. Students will use the guide before or after seeing the movie. "The guide will enhance the movie experience for students and extend the movie into classrooms," says Bonnie Eisenhamer, STScI's Hubble Formal Education manager. The Hubble Space Telescope is a project of international cooperation between NASA and the European Space Agency (ESA) and is managed by NASA’s Goddard Space Flight Center (GSFC) in Greenbelt, Md. The Space Telescope Science Institute (STScI) conducts Hubble science operations. The institute is operated for NASA by the Association of Universities for Research in Astronomy, Inc., Washington, D.C.

  1. Non-contrast enhanced MR venography using 3D fresh blood imaging (FBI): initial experience.

    PubMed

    Yokoyama, K; Nitatori, T; Inaoka, S; Takahara, T; Hachiya, J

    2001-01-01

    This study examined the efficacy of 3D-fresh blood imaging (FBI) in patients with venous disease in the iliac region to lower extremity. Fourteen patients with venous disease were examined [8 deep venous thrombosis (DVT) and 6 varix] by 3D-FBI and 2D-TOF MRA. All FBI images and 2D-TOF images were evaluated in terms of visualization of the disease and compared with conventional X-ray venography (CV). The total scan time of 3D-FBI ranged from 3 min 24 sec to 4 min 52 sec. 3D-FBI was positive in all 23 anatomical levels in which DVT was diagnosed by CV (100% sensitivity) as well as 2D-TOF. The delineation of collateral veins was superior or equal to that of 2D-TOF. 3D-FBI allowed depiction of varices in five of six cases; however, in one case, the evaluation was limited because the separation of arteries from veins was difficult. The 3D-FBI technique, which allows iliac to peripheral MR venography without contrast medium within a short acquisition time, is considered clinically useful.

  2. SpectraPLOT, Visualization Package with a User-Friendly Graphical Interface

    NASA Astrophysics Data System (ADS)

    Sebald, James; Macfarlane, Joseph; Golovkin, Igor

    2017-10-01

    SPECT3D is a collisional-radiative spectral analysis package designed to compute detailed emission, absorption, or x-ray scattering spectra, filtered images, XRD signals, and other synthetic diagnostics. The spectra and images are computed for virtual detectors by post-processing the results of hydrodynamics simulations in 1D, 2D, and 3D geometries. SPECT3D can account for a variety of instrumental response effects so that direct comparisons between simulations and experimental measurements can be made. SpectraPLOT is a user-friendly graphical interface for viewing a wide variety of results from SPECT3D simulations, and applying various instrumental effects to the simulated images and spectra. We will present SpectraPLOT's ability to display a variety of data, including spectra, images, light curves, streaked spectra, space-resolved spectra, and drilldown plasma property plots, for an argon-doped capsule implosion experiment example. Future SpectraPLOT features and enhancements will also be discussed.

  3. New software for 3D fracture network analysis and visualization

    NASA Astrophysics Data System (ADS)

    Song, J.; Noh, Y.; Choi, Y.; Um, J.; Hwang, S.

    2013-12-01

    This study presents new software to perform analysis and visualization of the fracture network system in 3D. The developed software modules for the analysis and visualization, such as BOUNDARY, DISK3D, FNTWK3D, CSECT and BDM, have been developed using Microsoft Visual Basic.NET and Visualization TookKit (VTK) open-source library. Two case studies revealed that each module plays a role in construction of analysis domain, visualization of fracture geometry in 3D, calculation of equivalent pipes, production of cross-section map and management of borehole data, respectively. The developed software for analysis and visualization of the 3D fractured rock mass can be used to tackle the geomechanical problems related to strength, deformability and hydraulic behaviors of the fractured rock masses.

  4. Vision System Measures Motions of Robot and External Objects

    NASA Technical Reports Server (NTRS)

    Talukder, Ashit; Matthies, Larry

    2008-01-01

    A prototype of an advanced robotic vision system both (1) measures its own motion with respect to a stationary background and (2) detects other moving objects and estimates their motions, all by use of visual cues. Like some prior robotic and other optoelectronic vision systems, this system is based partly on concepts of optical flow and visual odometry. Whereas prior optoelectronic visual-odometry systems have been limited to frame rates of no more than 1 Hz, a visual-odometry subsystem that is part of this system operates at a frame rate of 60 to 200 Hz, given optical-flow estimates. The overall system operates at an effective frame rate of 12 Hz. Moreover, unlike prior machine-vision systems for detecting motions of external objects, this system need not remain stationary: it can detect such motions while it is moving (even vibrating). The system includes a stereoscopic pair of cameras mounted on a moving robot. The outputs of the cameras are digitized, then processed to extract positions and velocities. The initial image-data-processing functions of this system are the same as those of some prior systems: Stereoscopy is used to compute three-dimensional (3D) positions for all pixels in the camera images. For each pixel of each image, optical flow between successive image frames is used to compute the two-dimensional (2D) apparent relative translational motion of the point transverse to the line of sight of the camera. The challenge in designing this system was to provide for utilization of the 3D information from stereoscopy in conjunction with the 2D information from optical flow to distinguish between motion of the camera pair and motions of external objects, compute the motion of the camera pair in all six degrees of translational and rotational freedom, and robustly estimate the motions of external objects, all in real time. To meet this challenge, the system is designed to perform the following image-data-processing functions: The visual-odometry subsystem (the subsystem that estimates the motion of the camera pair relative to the stationary background) utilizes the 3D information from stereoscopy and the 2D information from optical flow. It computes the relationship between the 3D and 2D motions and uses a least-mean-squares technique to estimate motion parameters. The least-mean-squares technique is suitable for real-time implementation when the number of external-moving-object pixels is smaller than the number of stationary-background pixels.

  5. Target surface finding using 3D SAR data

    NASA Astrophysics Data System (ADS)

    Ruiter, Jason R.; Burns, Joseph W.; Subotic, Nikola S.

    2005-05-01

    Methods of generating more literal, easily interpretable imagery from 3-D SAR data are being studied to provide all weather, near-visual target identification and/or scene interpretation. One method of approaching this problem is to automatically generate shape-based geometric renderings from the SAR data. In this paper we describe the application of the Marching Tetrahedrons surface finding algorithm to 3-D SAR data. The Marching Tetrahedrons algorithm finds a surface through the 3-D data cube, which provides a recognizable representation of the target surface. This algorithm was applied to the public-release X-patch simulations of a backhoe, which provided densely sampled 3-D SAR data sets. The performance of the algorithm to noise and spatial resolution were explored. Surface renderings were readily recognizable over a range of spatial resolution, and maintained their fidelity even under relatively low Signal-to-Noise Ratio (SNR) conditions.

  6. Synthesizing 3D Surfaces from Parameterized Strip Charts

    NASA Technical Reports Server (NTRS)

    Robinson, Peter I.; Gomez, Julian; Morehouse, Michael; Gawdiak, Yuri

    2004-01-01

    We believe 3D information visualization has the power to unlock new levels of productivity in the monitoring and control of complex processes. Our goal is to provide visual methods to allow for rapid human insight into systems consisting of thousands to millions of parameters. We explore this hypothesis in two complex domains: NASA program management and NASA International Space Station (ISS) spacecraft computer operations. We seek to extend a common form of visualization called the strip chart from 2D to 3D. A strip chart can display the time series progression of a parameter and allows for trends and events to be identified. Strip charts can be overlayed when multiple parameters need to visualized in order to correlate their events. When many parameters are involved, the direct overlaying of strip charts can become confusing and may not fully utilize the graphing area to convey the relationships between the parameters. We provide a solution to this problem by generating 3D surfaces from parameterized strip charts. The 3D surface utilizes significantly more screen area to illustrate the differences in the parameters and the overlayed strip charts, and it can rapidly be scanned by humans to gain insight. The selection of the third dimension must be a parallel or parameterized homogenous resource in the target domain, defined using a finite, ordered, enumerated type, and not a heterogeneous type. We demonstrate our concepts with examples from the NASA program management domain (assessing the state of many plans) and the computers of the ISS (assessing the state of many computers). We identify 2D strip charts in each domain and show how to construct the corresponding 3D surfaces. The user can navigate the surface, zooming in on regions of interest, setting a mark and drilling down to source documents from which the data points have been derived. We close by discussing design issues, related work, and implementation challenges.

  7. Training Performance of Laparoscopic Surgery in Two- and Three-Dimensional Displays.

    PubMed

    Lin, Chiuhsiang Joe; Cheng, Chih-Feng; Chen, Hung-Jen; Wu, Kuan-Ying

    2017-04-01

    This research investigated differences in the effects of a state-of-art stereoscopic 3-dimensional (3D) display and a traditional 2-dimensional (2D) display in simulated laparoscopic surgery over a longer duration than in previous publications and studied the learning effects of the 2 display systems on novices. A randomized experiment with 2 factors, image dimensions and image sequence, was conducted to investigate differences in the mean movement time, the mean error frequency, NASA-TLX cognitive workload, and visual fatigue in pegboard and circle-tracing tasks. The stereoscopic 3D display had advantages in mean movement time ( P < .001 and P = .002) and mean error frequency ( P = .010 and P = .008) in both the tasks. There were no significant differences in the objective visual fatigue ( P = .729 and P = .422) and in the NASA-TLX ( P = .605 and P = .937) cognitive workload between the 3D and the 2D displays on both the tasks. For the learning effect, participants who used the stereoscopic 3D display first had shorter mean movement time in the 2D display environment on both the pegboard ( P = .011) and the circle-tracing ( P = .017) tasks. The results of this research suggest that a stereoscopic system would not result in higher objective visual fatigue and cognitive workload than a 2D system, and it might reduce the performance time and increase the precision of surgical operations. In addition, learning efficiency of the stereoscopic system on the novices in this study demonstrated its value for training and education in laparoscopic surgery.

  8. Evaluating a Novel 3D Stereoscopic Visual Display for Transanal Endoscopic Surgery: A Randomized Controlled Crossover Study.

    PubMed

    Di Marco, Aimee N; Jeyakumar, Jenifa; Pratt, Philip J; Yang, Guang-Zhong; Darzi, Ara W

    2016-01-01

    To compare surgical performance with transanal endoscopic surgery (TES) using a novel 3-dimensional (3D) stereoscopic viewer against the current modalities of a 3D stereoendoscope, 3D, and 2-dimensional (2D) high-definition monitors. TES is accepted as the primary treatment for selected rectal tumors. Current TES systems offer a 2D monitor, or 3D image, viewed directly via a stereoendoscope, necessitating an uncomfortable operating position. To address this and provide a platform for future image augmentation, a 3D stereoscopic display was created. Forty participants, of mixed experience level, completed a simulated TES task using 4 visual displays (novel stereoscopic viewer and currently utilized stereoendoscope, 3D, and 2D high-definition monitors) in a randomly allocated order. Primary outcome measures were: time taken, path length, and accuracy. Secondary outcomes were: task workload and participant questionnaire results. Median time taken and path length were significantly shorter for the novel viewer versus 2D and 3D, and not significantly different to the traditional stereoendoscope. Significant differences were found in accuracy, task workload, and questionnaire assessment in favor of the novel viewer, as compared to all 3 modalities. This novel 3D stereoscopic viewer allows surgical performance in TES equivalent to that achieved using the current stereoendoscope and superior to standard 2D and 3D displays, but with lower physical and mental demands for the surgeon. Participants expressed a preference for this system, ranking it more highly on a questionnaire. Clinical translation of this work has begun with the novel viewer being used in 5 TES patients.

  9. A Real-time 3D Visualization of Global MHD Simulation for Space Weather Forecasting

    NASA Astrophysics Data System (ADS)

    Murata, K.; Matsuoka, D.; Kubo, T.; Shimazu, H.; Tanaka, T.; Fujita, S.; Watari, S.; Miyachi, H.; Yamamoto, K.; Kimura, E.; Ishikura, S.

    2006-12-01

    Recently, many satellites for communication networks and scientific observation are launched in the vicinity of the Earth (geo-space). The electromagnetic (EM) environments around the spacecraft are always influenced by the solar wind blowing from the Sun and induced electromagnetic fields. They occasionally cause various troubles or damages, such as electrification and interference, to the spacecraft. It is important to forecast the geo-space EM environment as well as the ground weather forecasting. Owing to the recent remarkable progresses of super-computer technologies, numerical simulations have become powerful research methods in the solar-terrestrial physics. For the necessity of space weather forecasting, NICT (National Institute of Information and Communications Technology) has developed a real-time global MHD simulation system of solar wind-magnetosphere-ionosphere couplings, which has been performed on a super-computer SX-6. The real-time solar wind parameters from the ACE spacecraft at every one minute are adopted as boundary conditions for the simulation. Simulation results (2-D plots) are updated every 1 minute on a NICT website. However, 3D visualization of simulation results is indispensable to forecast space weather more accurately. In the present study, we develop a real-time 3D webcite for the global MHD simulations. The 3-D visualization results of simulation results are updated every 20 minutes in the following three formats: (1)Streamlines of magnetic field lines, (2)Isosurface of temperature in the magnetosphere and (3)Isoline of conductivity and orthogonal plane of potential in the ionosphere. For the present study, we developed a 3-D viewer application working on Internet Explorer browser (ActiveX) is implemented, which was developed on the AVS/Express. Numerical data are saved in the HDF5 format data files every 1 minute. Users can easily search, retrieve and plot past simulation results (3D visualization data and numerical data) by using the STARS (Solar-terrestrial data Analysis and Reference System). The STARS is a data analysis system for satellite and ground-based observation data for solar-terrestrial physics.

  10. [Clinical application of accurate placement of lumbar pedicle screws using three-dimensional printing navigational templates under Quadrant system].

    PubMed

    Chen, Xuanhuang; Yu, Zhengxi; Wu, Changfu; Li, Xing; Chen, Xu; Zhang, Guodong; Zheng, Zugao; Lin, Haibin

    2017-02-01

    To explore the feasibility and the effectiveness of the accurate placement of lumbar pedicle screws using three-dimensional (3D) printing navigational templates in Quadrant minimally invasive system. The L 1-5 spines of 12 adult cadavers were scanned using CT. The 3D models of the lumbar spines were established. The screw trajectory was designed to pass through the central axis of the pedicle by using Mimics software. The navigational template was designed and 3D-printed according to the bony surface where the soft tissues could be removed. The placed screws were scanned using CT to create the 3D model again after operation. The 3D models of the designed trajectory and the placed screws were registered to evaluate the placed screws coincidence rate. Between November 2014 and November 2015, 31 patients with lumbar instability accepted surgery assisted with 3D-printing navigation module under Quadrant minimally invasive system. There were 14 males and 17 females, aged from 42 to 60 years, with an average of 45.2 years. The disease duration was 6-13 months (mean, 8.8 months). Single segment was involved in 15 cases, two segments in 13 cases, and three segments in 3 cases. Preoperative visual analogue scale (VAS) was 7.59±1.04; Oswestry disability index (ODI) was 76.21±5.82; and the Japanese Orthopaedic Association (JOA) score was 9.21±1.64. A total of 120 screws were placed in 12 cadavers specimens. The coincidence rate of placed screw was 100%. A total of 162 screws were implanted in 31 patients. The operation time was 65-147 minutes (mean, 102.23 minutes); the intraoperative blood loss was 50-116 mL (mean, 78.20 mL); and the intraoperative radiation exposure time was 8-54 seconds (mean, 42 seconds). At 3-7 days after operation, CT showed that the coincidence rate of the placed screws was 98.15% (159/162). At 4 weeks after operation, VAS, ODI, and JOA score were 2.24±0.80, 29.17±2.50, and 23.43±1.14 respectively, showing significant differences when compared with preoperative ones ( t =14.842, P =0.006; t =36.927, P =0.002; t =-36.031, P =0.001). Thirty-one patients were followed up 8-24 months (mean, 18.7 months). All incision healed by first intention, and no complication occurred. During the follow-up, X-ray film and CT showed that pedicle screw was accurately placed without loosening or breakage, and with good fusion of intervertebral bone graft. 3D-printing navigational templates in Quadrant minimally invasive system can help lumbar surgery gain minimal invasion, less radiation, and accurate placement.

  11. Plan to procedure: combining 3D templating with rapid prototyping to enhance pedicle screw placement

    NASA Astrophysics Data System (ADS)

    Augustine, Kurt E.; Stans, Anthony A.; Morris, Jonathan M.; Huddleston, Paul M.; Matsumoto, Jane M.; Holmes, David R., III; Robb, Richard A.

    2010-02-01

    Spinal fusion procedures involving the implantation of pedicle screws have steadily increased over the past decade because of demonstrated improvement in biomechanical stability of the spine. However, current methods of spinal fusion carries a risk of serious vascular, visceral, and neurological injury caused by inaccurate placement or inappropriately sized instrumentation, which may lead to patient paralysis or even fatality. 3D spine templating software developed by the Biomedical Imaging Resource (BIR) at Mayo Clinic allows the surgeon to virtually place pedicle screws using pre-operative 3D CT image data. With the template plan incorporated, a patient-specific 3D anatomic model is produced using a commercial rapid prototyping system. The pre-surgical plan and the patient-specific model then are used in the procedure room to provide real-time visualization and quantitative guidance for accurate placement of each pedicle screw, significantly reducing risk of injury. A pilot study was conducted at Mayo Clinic by the Department of Radiology, the Department of Orthopedics, and the BIR, involving seven complicated pediatric spine cases. In each case, pre-operative 3D templating was carried out and patient specific models were generated. The plans and the models were used intra-operatively, providing precise pedicle screw starting points and trajectories. Postoperative assessment by the surgeon confirmed all seven operations were successful. Results from the study suggest that patient-specific, 3D anatomic models successfully acquired from 3D templating tools are valuable for planning and conducting pedicle screw insertion procedures.

  12. Quantifying fracture geometry with X-ray tomography: Technique of Iterative Local Thresholding (TILT) for 3D image segmentation

    DOE PAGES

    Deng, Hang; Fitts, Jeffrey P.; Peters, Catherine A.

    2016-02-01

    This paper presents a new method—the Technique of Iterative Local Thresholding (TILT)—for processing 3D X-ray computed tomography (xCT) images for visualization and quantification of rock fractures. The TILT method includes the following advancements. First, custom masks are generated by a fracture-dilation procedure, which significantly amplifies the fracture signal on the intensity histogram used for local thresholding. Second, TILT is particularly well suited for fracture characterization in granular rocks because the multi-scale Hessian fracture (MHF) filter has been incorporated to distinguish fractures from pores in the rock matrix. Third, TILT wraps the thresholding and fracture isolation steps in an optimized iterativemore » routine for binary segmentation, minimizing human intervention and enabling automated processing of large 3D datasets. As an illustrative example, we applied TILT to 3D xCT images of reacted and unreacted fractured limestone cores. Other segmentation methods were also applied to provide insights regarding variability in image processing. The results show that TILT significantly enhanced separability of grayscale intensities, outperformed the other methods in automation, and was successful in isolating fractures from the porous rock matrix. Because the other methods are more likely to misclassify fracture edges as void and/or have limited capacity in distinguishing fractures from pores, those methods estimated larger fracture volumes (up to 80 %), surface areas (up to 60 %), and roughness (up to a factor of 2). In conclusion, these differences in fracture geometry would lead to significant disparities in hydraulic permeability predictions, as determined by 2D flow simulations.« less

  13. Short-term EEG dynamics and neural generators evoked by navigational images

    PubMed Central

    Leroy, Axelle; Cevallos, Carlos; Cebolla, Ana-Maria; Caharel, Stéphanie; Dan, Bernard

    2017-01-01

    The ecological environment offered by virtual reality is primarily supported by visual information. The different image contents and their rhythmic presentation imply specific bottom-up and top-down processing. Because these processes already occur during passive observation we studied the brain responses evoked by the presentation of specific 3D virtual tunnels with respect to 2D checkerboard. For this, we characterized electroencephalograhy dynamics (EEG), the evoked potentials and related neural generators involved in various visual paradigms. Time-frequency analysis showed modulation of alpha-beta oscillations indicating the presence of stronger prediction and after-effects of the 3D-tunnel with respect to the checkerboard. Whatever the presented image, the generators of the P100 were situated bilaterally in the occipital cortex (BA18, BA19) and in the right inferior temporal cortex (BA20). In checkerboard but not 3D-tunnel presentation, the left fusiform gyrus (BA37) was additionally recruited. P200 generators were situated in the temporal cortex (BA21) and the cerebellum (lobule VI/Crus I) specifically for the checkerboard while the right parahippocampal gyrus (BA36) and the cerebellum (lobule IV/V and IX/X) were involved only during the 3D-tunnel presentation. For both type of image, P300 generators were localized in BA37 but also in BA19, the right BA21 and the cerebellar lobule VI for only the checkerboard and the left BA20-BA21 for only the 3D-tunnel. Stronger P300 delta-theta oscillations recorded in this later situation point to a prevalence of the effect of changing direction over the proper visual content of the 3D-tunnel. The parahippocampal gyrus (BA36) implicated in navigation was also identified when the 3D-tunnel was compared to their scrambled versions, highlighting an action-oriented effect linked to navigational content. PMID:28632774

  14. Complex scenes and situations visualization in hierarchical learning algorithm with dynamic 3D NeoAxis engine

    NASA Astrophysics Data System (ADS)

    Graham, James; Ternovskiy, Igor V.

    2013-06-01

    We applied a two stage unsupervised hierarchical learning system to model complex dynamic surveillance and cyber space monitoring systems using a non-commercial version of the NeoAxis visualization software. The hierarchical scene learning and recognition approach is based on hierarchical expectation maximization, and was linked to a 3D graphics engine for validation of learning and classification results and understanding the human - autonomous system relationship. Scene recognition is performed by taking synthetically generated data and feeding it to a dynamic logic algorithm. The algorithm performs hierarchical recognition of the scene by first examining the features of the objects to determine which objects are present, and then determines the scene based on the objects present. This paper presents a framework within which low level data linked to higher-level visualization can provide support to a human operator and be evaluated in a detailed and systematic way.

  15. Figure-ground organization and the emergence of proto-objects in the visual cortex.

    PubMed

    von der Heydt, Rüdiger

    2015-01-01

    A long history of studies of perception has shown that the visual system organizes the incoming information early on, interpreting the 2D image in terms of a 3D world and producing a structure that provides perceptual continuity and enables object-based attention. Recordings from monkey visual cortex show that many neurons, especially in area V2, are selective for border ownership. These neurons are edge selective and have ordinary classical receptive fields (CRF), but in addition their responses are modulated (enhanced or suppressed) depending on the location of a 'figure' relative to the edge in their receptive field. Each neuron has a fixed preference for location on one side or the other. This selectivity is derived from the image context far beyond the CRF. This paper reviews evidence indicating that border ownership selectivity reflects the formation of early object representations ('proto-objects'). The evidence includes experiments showing (1) reversal of border ownership signals with change of perceived object structure, (2) border ownership specific enhancement of responses in object-based selective attention, (3) persistence of border ownership signals in accordance with continuity of object perception, and (4) remapping of border ownership signals across saccades and object movements. Findings 1 and 2 can be explained by hypothetical grouping circuits that sum contour feature signals in search of objectness, and, via recurrent projections, enhance the corresponding low-level feature signals. Findings 3 and 4 might be explained by assuming that the activity of grouping circuits persists and can be remapped. Grouping, persistence, and remapping are fundamental operations of vision. Finding these operations manifest in low-level visual areas challenges traditional views of visual processing. New computational models need to be developed for a comprehensive understanding of the function of the visual cortex.

  16. Figure–ground organization and the emergence of proto-objects in the visual cortex

    PubMed Central

    von der Heydt, Rüdiger

    2015-01-01

    A long history of studies of perception has shown that the visual system organizes the incoming information early on, interpreting the 2D image in terms of a 3D world and producing a structure that provides perceptual continuity and enables object-based attention. Recordings from monkey visual cortex show that many neurons, especially in area V2, are selective for border ownership. These neurons are edge selective and have ordinary classical receptive fields (CRF), but in addition their responses are modulated (enhanced or suppressed) depending on the location of a ‘figure’ relative to the edge in their receptive field. Each neuron has a fixed preference for location on one side or the other. This selectivity is derived from the image context far beyond the CRF. This paper reviews evidence indicating that border ownership selectivity reflects the formation of early object representations (‘proto-objects’). The evidence includes experiments showing (1) reversal of border ownership signals with change of perceived object structure, (2) border ownership specific enhancement of responses in object-based selective attention, (3) persistence of border ownership signals in accordance with continuity of object perception, and (4) remapping of border ownership signals across saccades and object movements. Findings 1 and 2 can be explained by hypothetical grouping circuits that sum contour feature signals in search of objectness, and, via recurrent projections, enhance the corresponding low-level feature signals. Findings 3 and 4 might be explained by assuming that the activity of grouping circuits persists and can be remapped. Grouping, persistence, and remapping are fundamental operations of vision. Finding these operations manifest in low-level visual areas challenges traditional views of visual processing. New computational models need to be developed for a comprehensive understanding of the function of the visual cortex. PMID:26579062

  17. Grazing-incidence coherent x-ray imaging in true reflection geometry

    NASA Astrophysics Data System (ADS)

    Sun, Tao; Jiang, Zhang; Strzalka, Joseph; Wang, Jin

    2012-02-01

    The development of the 3^rd and 4^th generation synchrotrons has stimulated extensive research activities in x-ray imaging techniques. Among all, coherent diffractive imaging (CDI) shows great promise, as its resolution is only limited by the wavelength of the source. Most of the CDI work reported thus far used transmission geometry, which however is not suitable for samples on opaque substrates or in which only the surfaces are the regions of interest. Even though two groups have performed CDI experiments (using laser or x-ray) in reflection geometry and succeeded in reconstructing the planar image of the surface, the theoretical underpinnings and analysis approaches of their techniques are essentially identical to transmission CDI. Most importantly, they couldn't obtain the structural information along sample thickness direction. Here, we introduce a reflection CDI technique that works at grazing-incidence geometry. By visualizing Au nanostructures fabricated on Si substrate, we demonstrate that this innovative imaging technique is capable of obtaining both 2D and 3D information of surfaces or buried structures in the samples. In the meanwhile, we will also explain the grazing-incidence-scattering based-algorithm developed for 3D phase retrieval.

  18. Pole Figure Explorer v. 1.8

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Van Benthem, Mark H.

    2016-05-04

    This software is employed for 3D visualization of X-ray diffraction (XRD) data with functionality for slicing, reorienting, isolating and plotting of 2D color contour maps and 3D renderings of large datasets. The program makes use of the multidimensionality of textured XRD data where diffracted intensity is not constant over a given set of angular positions (as dictated by the three defined dimensional angles of phi, chi, and two-theta). Datasets are rendered in 3D with intensity as a scaler which is represented as a rainbow color scale. A GUI interface and scrolling tools along with interactive function via the mouse allowmore » for fast manipulation of these large datasets so as to perform detailed analysis of diffraction results with full dimensionality of the diffraction space.« less

  19. Data Fusion and Visualization with the OpenEarth Framework (OEF)

    NASA Astrophysics Data System (ADS)

    Nadeau, D. R.; Baru, C.; Fouch, M. J.; Crosby, C. J.

    2010-12-01

    Data fusion is an increasingly important problem to solve as we strive to integrate data from multiple sources and build better models of the complex processes operating at the Earth’s surface and its interior. These data are often large, multi-dimensional, and subject to differing conventions for file formats, data structures, coordinate spaces, units of measure, and metadata organization. When visualized, these data require differing, and often conflicting, conventions for visual representations, dimensionality, icons, color schemes, labeling, and interaction. These issues make the visualization of fused Earth science data particularly difficult. The OpenEarth Framework (OEF) is an open-source data fusion and visualization suite of software being developed at the Supercomputer Center at the University of California, San Diego. Funded by the NSF, the project is leveraging virtual globe technology from NASA’s WorldWind to create interactive 3D visualization tools that combine layered data from a variety of sources to create a holistic view of features at, above, and beneath the Earth’s surface. The OEF architecture is cross-platform, multi-threaded, modular, and based upon Java. The OEF’s modular approach yields a collection of compatible mix-and-match components for assembling custom applications. Available modules support file format handling, web service communications, data management, data filtering, user interaction, and 3D visualization. File parsers handle a variety of formal and de facto standard file formats. Each one imports data into a general-purpose data representation that supports multidimensional grids, topography, points, lines, polygons, images, and more. From there these data then may be manipulated, merged, filtered, reprojected, and visualized. Visualization features support conventional and new visualization techniques for looking at topography, tomography, maps, and feature geometry. 3D grid data such as seismic tomography may be sliced by multiple oriented cutting planes and isosurfaced to create 3D skins that trace feature boundaries within the data. Topography may be overlaid with satellite imagery along with data such as gravity and magnetics measurements. Multiple data sets may be visualized simultaneously using overlapping layers and a common 3D+time coordinate space. Data management within the OEF handles and hides the quirks of differing file formats, web protocols, storage structures, coordinate spaces, and metadata representations. Derived data are computed automatically to support interaction and visualization while the original data is left unchanged in its original form. Data is cached for better memory and network efficiency, and all visualization is accelerated by 3D graphics hardware found on today’s computers. The OpenEarth Framework project is currently prototyping the software for use in the visualization, and integration of continental scale geophysical data being produced by EarthScope-related research in the Western US. The OEF is providing researchers with new ways to display and interrogate their data and is anticipated to be a valuable tool for future EarthScope-related research.

  20. Vergence–accommodation conflicts hinder visual performance and cause visual fatigue

    PubMed Central

    Hoffman, David M.; Girshick, Ahna R.; Akeley, Kurt; Banks, Martin S.

    2010-01-01

    Three-dimensional (3D) displays have become important for many applications including vision research, operation of remote devices, medical imaging, surgical training, scientific visualization, virtual prototyping, and more. In many of these applications, it is important for the graphic image to create a faithful impression of the 3D structure of the portrayed object or scene. Unfortunately, 3D displays often yield distortions in perceived 3D structure compared with the percepts of the real scenes the displays depict. A likely cause of such distortions is the fact that computer displays present images on one surface. Thus, focus cues—accommodation and blur in the retinal image—specify the depth of the display rather than the depths in the depicted scene. Additionally, the uncoupling of vergence and accommodation required by 3D displays frequently reduces one’s ability to fuse the binocular stimulus and causes discomfort and fatigue for the viewer. We have developed a novel 3D display that presents focus cues that are correct or nearly correct for the depicted scene. We used this display to evaluate the influence of focus cues on perceptual distortions, fusion failures, and fatigue. We show that when focus cues are correct or nearly correct, (1) the time required to identify a stereoscopic stimulus is reduced, (2) stereoacuity in a time-limited task is increased, (3) distortions in perceived depth are reduced, and (4) viewer fatigue and discomfort are reduced. We discuss the implications of this work for vision research and the design and use of displays. PMID:18484839

  1. Vibrational and rotational excitation effects of the N(2D) + D2(X1Σg +) → ND(X3Σ+) + D(2S) reaction

    NASA Astrophysics Data System (ADS)

    Zhu, Ziliang; Wang, Haijie; Wang, Xiquan; Shi, Yanying

    2018-05-01

    The effects of the rovibrational excitation of reactants in the N(2D) + D2(X1Σg+) → ND(X3Σ+) + D(2S) reaction are calculated in a collision energy range from the threshold to 1.0 eV using the time-dependent wave packet approach and a second-order split operator. The reaction probability, integral cross-section, differential cross-section and rate constant of the title reaction are calculated. The integral cross-section and rate constant of the initial states v = 0, j = 0, 1, are in good agreement with experimental data available in the literature. The rotational excitation of the D2 molecule has little effect on reaction probability, integral cross-section and the rate constant, but it increased the sideways and forward scattering signals. The vibrational excitation of the D2 molecule reduced the threshold and broke up the forward-backward symmetry of the differential cross-section; it also increased the forward scattering signals. This may be because the vibrational excitation of the D2 molecule reduced the lifetime of the intermediate complex.

  2. Interoperability, Data Control and Battlespace Visualization using XML, XSLT and X3D

    DTIC Science & Technology

    2003-09-01

    26 Rosenthal, Arnon, Seligman , Len and Costello, Roger, XML, Databases, and Interoperability, Federal Database Colloquium, AFCEA, San Diego...79 Rosenthal, Arnon, Seligman , Len and Costello, Roger, “XML, Databases, and Interoperability”, Federal Database Colloquium, AFCEA, San Diego, 1999... Linda , Mastering XML, Premium Edition, SYBEX, 2001 Wooldridge, Michael , An Introduction to MultiAgent Systems, Wiley, 2002 PAPERS Abernathy, M

  3. A three-dimensional bucking system for optimal bucking of Central Appalachian hardwoods

    Treesearch

    Jingxin Wang; Jingang Liu; Chris B. LeDoux

    2009-01-01

    An optimal tree stembucking systemwas developed for central Appalachian hardwood species using three-dimensional (3D) modeling techniques. ActiveX Data Objects were implemented via MS Visual C++/OpenGL to manipulate tree data which were supported by a backend relational data model with five data entity types for stems, grades and prices, logs, defects, and stem shapes...

  4. The Impact of Interactivity on Comprehending 2D and 3D Visualizations of Movement Data.

    PubMed

    Amini, Fereshteh; Rufiange, Sebastien; Hossain, Zahid; Ventura, Quentin; Irani, Pourang; McGuffin, Michael J

    2015-01-01

    GPS, RFID, and other technologies have made it increasingly common to track the positions of people and objects over time as they move through two-dimensional spaces. Visualizing such spatio-temporal movement data is challenging because each person or object involves three variables (two spatial variables as a function of the time variable), and simply plotting the data on a 2D geographic map can result in overplotting and occlusion that hides details. This also makes it difficult to understand correlations between space and time. Software such as GeoTime can display such data with a three-dimensional visualization, where the 3rd dimension is used for time. This allows for the disambiguation of spatially overlapping trajectories, and in theory, should make the data clearer. However, previous experimental comparisons of 2D and 3D visualizations have so far found little advantage in 3D visualizations, possibly due to the increased complexity of navigating and understanding a 3D view. We present a new controlled experimental comparison of 2D and 3D visualizations, involving commonly performed tasks that have not been tested before, and find advantages in 3D visualizations for more complex tasks. In particular, we tease out the effects of various basic interactions and find that the 2D view relies significantly on "scrubbing" the timeline, whereas the 3D view relies mainly on 3D camera navigation. Our work helps to improve understanding of 2D and 3D visualizations of spatio-temporal data, particularly with respect to interactivity.

  5. A virtual laboratory for neutron and synchrotron strain scanning

    NASA Astrophysics Data System (ADS)

    James, J. A.; Santisteban, J. R.; Edwards, L.; Daymond, M. R.

    2004-07-01

    The new generation of dedicated Engineering Strain Scanners at neutron and synchrotron facilities offer considerable improvements in both counting time and spatial resolution. In order to make full use of these advances in instrumentation, the routine tasks associated with setting up measurement runs and analysing the data need to be made as efficient as possible. Such tasks include the planning of the experiment, the alignment and positioning of the specimen, the least-squares refinement of diffraction spectra, the definition of strain in the sample coordinate system, and its visualization within a 3D model of the specimen. With this aim in mind, we have written a software providing support for most of these operations. The approach is based on a virtual lab consisting of 3D models of the sample and laboratory equipment. The system has been developed for ENGIN-X, the new engineering strain scanner recently commissioned at ISIS, but it is flexible enough to be ported to other neutron or synchrotron strain scanners. The software has been designed with visiting industrial and academic researchers in mind, users who need to be able to control the instrument after only a short period of training.

  6. Open source 3D visualization and interaction dedicated to hydrological models

    NASA Astrophysics Data System (ADS)

    Richard, Julien; Giangola-Murzyn, Agathe; Gires, Auguste; Tchiguirinskaia, Ioulia; Schertzer, Daniel

    2014-05-01

    Climate change and surface urbanization strongly modify the hydrological cycle in urban areas, increasing the consequences of extreme events such as floods or draughts. These issues lead to the development of the Multi-Hydro model at the Ecole des Ponts ParisTech (A. Giangola-Murzyn et al., 2012). This fully distributed model allows to compute the hydrological response of urban and peri-urban areas. Unfortunately such models are seldom user friendly. Indeed generating the inputs before launching a new simulation is usually a tricky tasks, and understanding and interpreting the outputs remains specialist tasks not accessible to the wider public. The MH-AssimTool was developed to overcome these issues. To enable an easier and improved understanding of the model outputs, we decided to convert the raw output data (grids file in ascii format) to a 3D display. Some commercial paying models provide a 3D visualization. Because of the cost of their licenses, this kind of tools may not be accessible to the most concerned stakeholders. So, we are developing a new tool based on C++ for the computation, Qt for the graphic user interface, QGIS for the geographical side and OpenGL for the 3D display. All these languages and libraries are open source and multi-platform. We will discuss some preprocessing issues for the data conversion from 2.5D to 3D. Indeed, the GIS data, is considered as a 2.5D (e.i. 2D polygon + one height) and the its transform to 3D display implies a lot of algorithms. For example,to visualize in 3D one building, it is needed to have for each point the coordinates and the elevation according to the topography. Furthermore one have to create new points to represent the walls. Finally the interactions between the model and stakeholders through this new interface and how this helps converting a research tool into a an efficient operational decision tool will be discussed. This ongoing research on the improvement of the visualization methods is supported by the KIC-Climate Blue Green Dream project.

  7. Impact of 3D vision on mental workload and laparoscopic performance in inexperienced subjects.

    PubMed

    Gómez-Gómez, E; Carrasco-Valiente, J; Valero-Rosa, J; Campos-Hernández, J P; Anglada-Curado, F J; Carazo-Carazo, J L; Font-Ugalde, P; Requena-Tapia, M J

    2015-05-01

    To assess the effect of vision in three dimensions (3D) versus two dimensions (2D) on mental workload and laparoscopic performance during simulation-based training. A prospective, randomized crossover study on inexperienced students in operative laparoscopy was conducted. Forty-six candidates executed five standardized exercises on a pelvitrainer with both vision systems (3D and 2D). Laparoscopy performance was assessed using the total time (in seconds) and the number of failed attempts. For workload assessment, the validated NASA-TLX questionnaire was administered. 3D vision improves the performance reducing the time (3D = 1006.08 ± 315.94 vs. 2D = 1309.17 ± 300.28; P < .001) and the total number of failed attempts (3D = .84 ± 1.26 vs. 2D = 1.86 ± 1.60; P < .001). For each exercise, 3D vision also shows better performance times: "transfer objects" (P = .001), "single knot" (P < .001), "clip and cut" (P < .05), and "needle guidance" (P < .001). Besides, according to the NASA-TLX results, less mental workload is experienced with the use of 3D (P < .001). However, 3D vision was associated with greater visual impairment (P < .01) and headaches (P < .05). The incorporation of 3D systems in laparoscopic training programs would facilitate the acquisition of laparoscopic skills, because they reduce mental workload and improve the performance on inexperienced surgeons. However, some undesirable effects such as visual discomfort or headache are identified initially. Copyright © 2014 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. Integrated remote sensing and visualization (IRSV) system for transportation infrastructure operations and management, phase two, volume 2 : applications of LiDAR technology in structural evaluation under normal traffic operation and post blast loading.

    DOT National Transportation Integrated Search

    2012-03-01

    This report focused on two potential applications of terrestrial LiDAR scans on highway : bridges: 1) vehicle crossing effects measured by3-D, terrestrial LiDAR scans of highway bridges : measuring clearance distance; and 2) bridge post-blast geometr...

  9. Pose estimation of industrial objects towards robot operation

    NASA Astrophysics Data System (ADS)

    Niu, Jie; Zhou, Fuqiang; Tan, Haishu; Cao, Yu

    2017-10-01

    With the advantages of wide range, non-contact and high flexibility, the visual estimation technology of target pose has been widely applied in modern industry, robot guidance and other engineering practices. However, due to the influence of complicated industrial environment, outside interference factors, lack of object characteristics, restrictions of camera and other limitations, the visual estimation technology of target pose is still faced with many challenges. Focusing on the above problems, a pose estimation method of the industrial objects is developed based on 3D models of targets. By matching the extracted shape characteristics of objects with the priori 3D model database of targets, the method realizes the recognition of target. Thus a pose estimation of objects can be determined based on the monocular vision measuring model. The experimental results show that this method can be implemented to estimate the position of rigid objects based on poor images information, and provides guiding basis for the operation of the industrial robot.

  10. F/FB-111 Avionic Systems Career Ladder, AFSC 452X3

    DTIC Science & Technology

    1990-07-01

    Computer products upon which this report is based are available for use by operations and training officials. The survey instrument was developed by Chief...AND BLOWER 60 64 51 GAS TURBINE GENERATOR/COMPRESSOR 57 64 60 AIRCRAFT RADIO 56 59 62 NITROGEN SERVICING EQUIPMENT 30 34 25 TABLE 13B EQUIPMENT USED OR...F-nf W< < W O / O CD S-c Cr ZC F ODf -C CD ;Z D r- =D CO M1 wD >) C U CCD4F ~-jF-ca- Cr. F- C).FW C) - En z_; > X F-F - : > - < xJC<C -)I-CrF- W.JDLU

  11. Comparison of scoliosis measurements based on three-dimensional vertebra vectors and conventional two-dimensional measurements: advantages in evaluation of prognosis and surgical results.

    PubMed

    Illés, Tamás; Somoskeöy, Szabolcs

    2013-06-01

    A new concept of vertebra vectors based on spinal three-dimensional (3D) reconstructions of images from the EOS system, a new low-dose X-ray imaging device, was recently proposed to facilitate interpretation of EOS 3D data, especially with regard to horizontal plane images. This retrospective study was aimed at the evaluation of the spinal layout visualized by EOS 3D and vertebra vectors before and after surgical correction, the comparison of scoliotic spine measurement values based on 3D vertebra vectors with measurements using conventional two-dimensional (2D) methods, and an evaluation of horizontal plane vector parameters for their relationship with the magnitude of scoliotic deformity. 95 patients with adolescent idiopathic scoliosis operated according to the Cotrel-Dubousset principle were subjected to EOS X-ray examinations pre- and postoperatively, followed by 3D reconstructions and generation of vertebra vectors in a calibrated coordinate system to calculate vector coordinates and parameters, as published earlier. Differences in values of conventional 2D Cobb methods and methods based on vertebra vectors were evaluated by means comparison T test and relationship of corresponding parameters was analysed by bivariate correlation. Relationship of horizontal plane vector parameters with the magnitude of scoliotic deformities and results of surgical correction were analysed by Pearson correlation and linear regression. In comparison to manual 2D methods, a very close relationship was detectable in vertebra vector-based curvature data for coronal curves (preop r 0.950, postop r 0.935) and thoracic kyphosis (preop r 0.893, postop r 0.896), while the found small difference in L1-L5 lordosis values (preop r 0.763, postop r 0.809) was shown to be strongly related to the magnitude of corresponding L5 wedge. The correlation analysis results revealed strong correlation between the magnitude of scoliosis and the lateral translation of apical vertebra in horizontal plane. The horizontal plane coordinates of the terminal and initial points of apical vertebra vectors represent this (r 0.701; r 0.667). Less strong correlation was detected in the axial rotation of apical vertebras and the magnitudes of the frontal curves (r 0.459). Vertebra vectors provide a key opportunity to visualize spinal deformities in all three planes simultaneously. Measurement methods based on vertebral vectors proved to be just as accurate and reliable as conventional measurement methods for coronal and sagittal plane parameters. In addition, the horizontal plane display of the curves can be studied using the same vertebra vectors. Based on the vertebra vectors data, during the surgical treatment of spinal deformities, the diminution of the lateral translation of the vertebras seems to be more important in the results of the surgical correction than the correction of the axial rotation.

  12. 3D Scientific Visualization with Blender

    NASA Astrophysics Data System (ADS)

    Kent, Brian R.

    2015-03-01

    This is the first book written on using Blender (an open source visualization suite widely used in the entertainment and gaming industries) for scientific visualization. It is a practical and interesting introduction to Blender for understanding key parts of 3D rendering and animation that pertain to the sciences via step-by-step guided tutorials. 3D Scientific Visualization with Blender takes you through an understanding of 3D graphics and modelling for different visualization scenarios in the physical sciences.

  13. Three dimensional fabric evolution of sheared sand

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hasan, Alsidqi; Alshibli, Khalid

    2012-10-24

    Granular particles undergo translation and rolling when they are sheared. This paper presents a three-dimensional (3D) experimental assessment of fabric evolution of sheared sand at the particle level. F-75 Ottawa sand specimen was tested under an axisymmetric triaxial loading condition. It measured 9.5 mm in diameter and 20 mm in height. The quantitative evaluation was conducted by analyzing 3D high-resolution x-ray synchrotron micro-tomography images of the specimen at eight axial strain levels. The analyses included visualization of particle translation and rotation, and quantification of fabric orientation as shearing continued. Representative individual particles were successfully tracked and visualized to assess themore » mode of interaction between them. This paper discusses fabric evolution and compares the evolution of particles within and outside the shear band as shearing continues. Changes in particle orientation distributions are presented using fabric histograms and fabric tensor.« less

  14. Calcification detection of abdominal aorta in CT images and 3D visualization in VR devices.

    PubMed

    Garcia-Berna, Jose A; Sanchez-Gomez, Juan M; Hermanns, Judith; Garcia-Mateos, Gines; Fernandez-Aleman, Jose L

    2016-08-01

    Automatic calcification detection in abdominal aorta consists of a set of computer vision techniques to quantify the amount of calcium that is found around this artery. Knowing that information, it is possible to perform statistical studies that relate vascular diseases with the presence of calcium in these structures. To facilitate the detection in CT images, a contrast is usually injected into the circulatory system of the patients to distinguish the aorta from other body tissues and organs. This contrast increases the absorption of X-rays by human blood, making it easier the measurement of calcifications. Based on this idea, a new system capable of detecting and tracking the aorta artery has been developed with an estimation of the calcium found surrounding the aorta. Besides, the system is complemented with a 3D visualization mode of the image set which is designed for the new generation of immersive VR devices.

  15. Evaluation of stereoscopic display with visual function and interview

    NASA Astrophysics Data System (ADS)

    Okuyama, Fumio

    1999-05-01

    The influence of binocular stereoscopic (3D) television display on the human eye were compared with one of a 2D display, using human visual function testing and interviews. A 40- inch double lenticular display was used for 2D/3D comparison experiments. Subjects observed the display for 30 minutes at a distance 1.0 m, with a combination of 2D material and one of 3D material. The participants were twelve young adults. Main optometric test with visual function measured were visual acuity, refraction, phoria, near vision point, accommodation etc. The interview consisted of 17 questions. Testing procedures were performed just before watching, just after watching, and forty-five minutes after watching. Changes in visual function are characterized as prolongation of near vision point, decrease of accommodation and increase in phoria. 3D viewing interview results show much more visual fatigue in comparison with 2D results. The conclusions are: 1) change in visual function is larger and visual fatigue is more intense when viewing 3D images. 2) The evaluation method with visual function and interview proved to be very satisfactory for analyzing the influence of stereoscopic display on human eye.

  16. Image analysis for dental bone quality assessment using CBCT imaging

    NASA Astrophysics Data System (ADS)

    Suprijanto; Epsilawati, L.; Hajarini, M. S.; Juliastuti, E.; Susanti, H.

    2016-03-01

    Cone beam computerized tomography (CBCT) is one of X-ray imaging modalities that are applied in dentistry. Its modality can visualize the oral region in 3D and in a high resolution. CBCT jaw image has potential information for the assessment of bone quality that often used for pre-operative implant planning. We propose comparison method based on normalized histogram (NH) on the region of inter-dental septum and premolar teeth. Furthermore, the NH characteristic from normal and abnormal bone condition are compared and analyzed. Four test parameters are proposed, i.e. the difference between teeth and bone average intensity (s), the ratio between bone and teeth average intensity (n) of NH, the difference between teeth and bone peak value (Δp) of NH, and the ratio between teeth and bone of NH range (r). The results showed that n, s, and Δp have potential to be the classification parameters of dental calcium density.

  17. PuMA: the Porous Microstructure Analysis software

    NASA Astrophysics Data System (ADS)

    Ferguson, Joseph C.; Panerai, Francesco; Borner, Arnaud; Mansour, Nagi N.

    2018-01-01

    The Porous Microstructure Analysis (PuMA) software has been developed in order to compute effective material properties and perform material response simulations on digitized microstructures of porous media. PuMA is able to import digital three-dimensional images obtained from X-ray microtomography or to generate artificial microstructures. PuMA also provides a module for interactive 3D visualizations. Version 2.1 includes modules to compute porosity, volume fractions, and surface area. Two finite difference Laplace solvers have been implemented to compute the continuum tortuosity factor, effective thermal conductivity, and effective electrical conductivity. A random method has been developed to compute tortuosity factors from the continuum to rarefied regimes. Representative elementary volume analysis can be performed on each property. The software also includes a time-dependent, particle-based model for the oxidation of fibrous materials. PuMA was developed for Linux operating systems and is available as a NASA software under a US & Foreign release.

  18. Registration of multiple video images to preoperative CT for image-guided surgery

    NASA Astrophysics Data System (ADS)

    Clarkson, Matthew J.; Rueckert, Daniel; Hill, Derek L.; Hawkes, David J.

    1999-05-01

    In this paper we propose a method which uses multiple video images to establish the pose of a CT volume with respect to video camera coordinates for use in image guided surgery. The majority of neurosurgical procedures require the neurosurgeon to relate the pre-operative MR/CT data to the intra-operative scene. Registration of 2D video images to the pre-operative 3D image enables a perspective projection of the pre-operative data to be overlaid onto the video image. Our registration method is based on image intensity and uses a simple iterative optimization scheme to maximize the mutual information between a video image and a rendering from the pre-operative data. Video images are obtained from a stereo operating microscope, with a field of view of approximately 110 X 80 mm. We have extended an existing information theoretical framework for 2D-3D registration, so that multiple video images can be registered simultaneously to the pre-operative data. Experiments were performed on video and CT images of a skull phantom. We took three video images, and our algorithm registered these individually to the 3D image. The mean projection error varied between 4.33 and 9.81 millimeters (mm), and the mean 3D error varied between 4.47 and 11.92 mm. Using our novel techniques we then registered five video views simultaneously to the 3D model. This produced an accurate and robust registration with a mean projection error of 0.68 mm and a mean 3D error of 1.05 mm.

  19. Integrating Time-Synchronized Video with Other Geospatial and Temporal Data for Remote Science Operations

    NASA Technical Reports Server (NTRS)

    Cohen, Tamar E.; Lees, David S.; Deans, Matthew C.; Lim, Darlene S. S.; Lee, Yeon Jin Grace

    2018-01-01

    Exploration Ground Data Systems (xGDS) supports rapid scientific decision making by synchronizing video in context with map, instrument data visualization, geo-located notes and any other collected data. xGDS is an open source web-based software suite developed at NASA Ames Research Center to support remote science operations in analog missions and prototype solutions for remote planetary exploration. (See Appendix B) Typical video systems are designed to play or stream video only, independent of other data collected in the context of the video. Providing customizable displays for monitoring live video and data as well as replaying recorded video and data helps end users build up a rich situational awareness. xGDS was designed to support remote field exploration with unreliable networks. Commercial digital recording systems operate under the assumption that there is a stable and reliable network between the source of the video and the recording system. In many field deployments and space exploration scenarios, this is not the case - there are both anticipated and unexpected network losses. xGDS' Video Module handles these interruptions, storing the available video, organizing and characterizing the dropouts, and presenting the video for streaming or replay to the end user including visualization of the dropouts. Scientific instruments often require custom or expensive software to analyze and visualize collected data. This limits the speed at which the data can be visualized and limits access to the data to those users with the software. xGDS' Instrument Module integrates with instruments that collect and broadcast data in a single snapshot or that continually collect and broadcast a stream of data. While seeing a visualization of collected instrument data is informative, showing the context for the collected data, other data collected nearby along with events indicating current status helps remote science teams build a better understanding of the environment. Further, sharing geo-located, tagged notes recorded by the scientists and others on the team spurs deeper analysis of the data.

  20. Automated UAV-based mapping for airborne reconnaissance and video exploitation

    NASA Astrophysics Data System (ADS)

    Se, Stephen; Firoozfam, Pezhman; Goldstein, Norman; Wu, Linda; Dutkiewicz, Melanie; Pace, Paul; Naud, J. L. Pierre

    2009-05-01

    Airborne surveillance and reconnaissance are essential for successful military missions. Such capabilities are critical for force protection, situational awareness, mission planning, damage assessment and others. UAVs gather huge amount of video data but it is extremely labour-intensive for operators to analyse hours and hours of received data. At MDA, we have developed a suite of tools towards automated video exploitation including calibration, visualization, change detection and 3D reconstruction. The on-going work is to improve the robustness of these tools and automate the process as much as possible. Our calibration tool extracts and matches tie-points in the video frames incrementally to recover the camera calibration and poses, which are then refined by bundle adjustment. Our visualization tool stabilizes the video, expands its field-of-view and creates a geo-referenced mosaic from the video frames. It is important to identify anomalies in a scene, which may include detecting any improvised explosive devices (IED). However, it is tedious and difficult to compare video clips to look for differences manually. Our change detection tool allows the user to load two video clips taken from two passes at different times and flags any changes between them. 3D models are useful for situational awareness, as it is easier to understand the scene by visualizing it in 3D. Our 3D reconstruction tool creates calibrated photo-realistic 3D models from video clips taken from different viewpoints, using both semi-automated and automated approaches. The resulting 3D models also allow distance measurements and line-of- sight analysis.

  1. Dynamical Segmentation of the Left Ventricle in Echocardiographic Image Sequences

    DTIC Science & Technology

    2001-10-25

    LV in echocardiographic images using 3D deformable models and superquadrics” EMBS-2000. Vol. 3, 2000, pp. 1724 -1727 [7] Malladi R , Sethian J, Vemuri...very noisy images. An original external energy P is determined automatically and stabilizes the snake on the boundary: ( ) . , ,P r k x y z...1) where r is a constant fixed by the operator and ( ), ,k x y z depends on the image gradient : ( ) 1, , 1 _ k x y z Grad Mod

  2. Technical Note: A 3-D rendering algorithm for electromechanical wave imaging of a beating heart.

    PubMed

    Nauleau, Pierre; Melki, Lea; Wan, Elaine; Konofagou, Elisa

    2017-09-01

    Arrhythmias can be treated by ablating the heart tissue in the regions of abnormal contraction. The current clinical standard provides electroanatomic 3-D maps to visualize the electrical activation and locate the arrhythmogenic sources. However, the procedure is time-consuming and invasive. Electromechanical wave imaging is an ultrasound-based noninvasive technique that can provide 2-D maps of the electromechanical activation of the heart. In order to fully visualize the complex 3-D pattern of activation, several 2-D views are acquired and processed separately. They are then manually registered with a 3-D rendering software to generate a pseudo-3-D map. However, this last step is operator-dependent and time-consuming. This paper presents a method to generate a full 3-D map of the electromechanical activation using multiple 2-D images. Two canine models were considered to illustrate the method: one in normal sinus rhythm and one paced from the lateral region of the heart. Four standard echographic views of each canine heart were acquired. Electromechanical wave imaging was applied to generate four 2-D activation maps of the left ventricle. The radial positions and activation timings of the walls were automatically extracted from those maps. In each slice, from apex to base, these values were interpolated around the circumference to generate a full 3-D map. In both cases, a 3-D activation map and a cine-loop of the propagation of the electromechanical wave were automatically generated. The 3-D map showing the electromechanical activation timings overlaid on realistic anatomy assists with the visualization of the sources of earlier activation (which are potential arrhythmogenic sources). The earliest sources of activation corresponded to the expected ones: septum for the normal rhythm and lateral for the pacing case. The proposed technique provides, automatically, a 3-D electromechanical activation map with a realistic anatomy. This represents a step towards a noninvasive tool to efficiently localize arrhythmias in 3-D. © 2017 American Association of Physicists in Medicine.

  3. Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation.

    PubMed

    Arujuna, Aruna V; Housden, R James; Ma, Yingliang; Rajani, Ronak; Gao, Gang; Nijhof, Niels; Cathier, Pascal; Bullens, Roland; Gijsbers, Geert; Parish, Victoria; Kapetanakis, Stamatis; Hancock, Jane; Rinaldi, C Aldo; Cooklin, Michael; Gill, Jaswinder; Thomas, Martyn; O'neill, Mark D; Razavi, Reza; Rhode, Kawal S

    2014-01-01

    Real-time imaging is required to guide minimally invasive catheter-based cardiac interventions. While transesophageal echocardiography allows for high-quality visualization of cardiac anatomy, X-ray fluoroscopy provides excellent visualization of devices. We have developed a novel image fusion system that allows real-time integration of 3-D echocardiography and the X-ray fluoroscopy. The system was validated in the following two stages: 1) preclinical to determine function and validate accuracy; and 2) in the clinical setting to assess clinical workflow feasibility and determine overall system accuracy. In the preclinical phase, the system was assessed using both phantom and porcine experimental studies. Median 2-D projection errors of 4.5 and 3.3 mm were found for the phantom and porcine studies, respectively. The clinical phase focused on extending the use of the system to interventions in patients undergoing either atrial fibrillation catheter ablation (CA) or transcatheter aortic valve implantation (TAVI). Eleven patients were studied with nine in the CA group and two in the TAVI group. Successful real-time view synchronization was achieved in all cases with a calculated median distance error of 2.2 mm in the CA group and 3.4 mm in the TAVI group. A standard clinical workflow was established using the image fusion system. These pilot data confirm the technical feasibility of accurate real-time echo-fluoroscopic image overlay in clinical practice, which may be a useful adjunct for real-time guidance during interventional cardiac procedures.

  4. On Volterra quadratic stochastic operators with continual state space

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ganikhodjaev, Nasir; Hamzah, Nur Zatul Akmar

    2015-05-15

    Let (X,F) be a measurable space, and S(X,F) be the set of all probability measures on (X,F) where X is a state space and F is σ - algebraon X. We consider a nonlinear transformation (quadratic stochastic operator) defined by (Vλ)(A) = ∫{sub X}∫{sub X}P(x,y,A)dλ(x)dλ(y), where P(x, y, A) is regarded as a function of two variables x and y with fixed A ∈ F . A quadratic stochastic operator V is called a regular, if for any initial measure the strong limit lim{sub n→∞} V{sup n }(λ) is exists. In this paper, we construct a family of quadratic stochastic operators defined on themore » segment X = [0,1] with Borel σ - algebra F on X , prove their regularity and show that the limit measure is a Dirac measure.« less

  5. Evaluation of microvascular anastomosis using real-time ultrahigh resolution Fourier domain Doppler optical coherence tomography

    PubMed Central

    Huang, Yong; Tong, Dedi; Zhu, Shan; Wu, Lehao; Mao, Qi; Ibrahim, Zuhaib; Lee, WP Andrew; Brandacher, Gerald; Kang, Jin U.

    2014-01-01

    Background Evolution and improvements in microsurgical techniques and tools have paved the way for super-microsurgical anastomoses with vessel diameters often approaching below 0.8 mm in the clinical realm and even smaller (0.2–0.3 mm) in murine models. Several imaging and monitoring devices have been introduced for post-operative monitoring but intra-operative guidance, assessment and predictability have remained limited to binocular optical microscope and surgeon’s experience. We present a high-resolution real time 3D imaging modality for intra-operative evaluation of luminal narrowing, thrombus formation and flow alterations. Methods An imaging modality that provides immediate, in-depth high resolution 3D structure view and flow information of the anastomosed site called phase resolved Doppler optical coherence tomography (PRDOCT) was developed. 22 mouse femoral artery anastomoses and 17 mouse venous anastomoses were performed and evaluated with PRDOCT. Flow status, vessel inner lumen 3D structure, and early thrombus detection were analyzed based on PRDOCT imaging results. Initial PRDOCT based predictions were correlated with actual long term surgical outcomes. Eventually four cases of mouse orthotopic limb transplantation were carried out and PRDOCT predicted long term patency were confirmed by actual results. Results PRDOCT was able to provide high-resolution 3D visualization of the vessel flow status and vessel inner lumen. The assessments based on PRDOCT visualization shows a 92% sensitivity and 90% specificity for arterial anastomoses and 90% sensitivity and 86% specificity for venous anastomoses. Conclusions PRDOCT is an effective evaluation tool for microvascular anastomosis. It can predict the long term vessel patency with high sensitivity and specificity. PMID:25811583

  6. 3D Scientific Visualization with Blender

    NASA Astrophysics Data System (ADS)

    Kent, Brian R.

    2015-03-01

    This is the first book written on using Blender for scientific visualization. It is a practical and interesting introduction to Blender for understanding key parts of 3D rendering and animation that pertain to the sciences via step-by-step guided tutorials. 3D Scientific Visualization with Blender takes you through an understanding of 3D graphics and modelling for different visualization scenarios in the physical sciences.

  7. HiCTMap: Detection and analysis of chromosome territory structure and position by high-throughput imaging.

    PubMed

    Jowhar, Ziad; Gudla, Prabhakar R; Shachar, Sigal; Wangsa, Darawalee; Russ, Jill L; Pegoraro, Gianluca; Ried, Thomas; Raznahan, Armin; Misteli, Tom

    2018-06-01

    The spatial organization of chromosomes in the nuclear space is an extensively studied field that relies on measurements of structural features and 3D positions of chromosomes with high precision and robustness. However, no tools are currently available to image and analyze chromosome territories in a high-throughput format. Here, we have developed High-throughput Chromosome Territory Mapping (HiCTMap), a method for the robust and rapid analysis of 2D and 3D chromosome territory positioning in mammalian cells. HiCTMap is a high-throughput imaging-based chromosome detection method which enables routine analysis of chromosome structure and nuclear position. Using an optimized FISH staining protocol in a 384-well plate format in conjunction with a bespoke automated image analysis workflow, HiCTMap faithfully detects chromosome territories and their position in 2D and 3D in a large population of cells per experimental condition. We apply this novel technique to visualize chromosomes 18, X, and Y in male and female primary human skin fibroblasts, and show accurate detection of the correct number of chromosomes in the respective genotypes. Given the ability to visualize and quantitatively analyze large numbers of nuclei, we use HiCTMap to measure chromosome territory area and volume with high precision and determine the radial position of chromosome territories using either centroid or equidistant-shell analysis. The HiCTMap protocol is also compatible with RNA FISH as demonstrated by simultaneous labeling of X chromosomes and Xist RNA in female cells. We suggest HiCTMap will be a useful tool for routine precision mapping of chromosome territories in a wide range of cell types and tissues. Published by Elsevier Inc.

  8. GenomeD3Plot: a library for rich, interactive visualizations of genomic data in web applications.

    PubMed

    Laird, Matthew R; Langille, Morgan G I; Brinkman, Fiona S L

    2015-10-15

    A simple static image of genomes and associated metadata is very limiting, as researchers expect rich, interactive tools similar to the web applications found in the post-Web 2.0 world. GenomeD3Plot is a light weight visualization library written in javascript using the D3 library. GenomeD3Plot provides a rich API to allow the rapid visualization of complex genomic data using a convenient standards based JSON configuration file. When integrated into existing web services GenomeD3Plot allows researchers to interact with data, dynamically alter the view, or even resize or reposition the visualization in their browser window. In addition GenomeD3Plot has built in functionality to export any resulting genome visualization in PNG or SVG format for easy inclusion in manuscripts or presentations. GenomeD3Plot is being utilized in the recently released Islandviewer 3 (www.pathogenomics.sfu.ca/islandviewer/) to visualize predicted genomic islands with other genome annotation data. However, its features enable it to be more widely applicable for dynamic visualization of genomic data in general. GenomeD3Plot is licensed under the GNU-GPL v3 at https://github.com/brinkmanlab/GenomeD3Plot/. brinkman@sfu.ca. © The Author 2015. Published by Oxford University Press.

  9. An Interdisciplinary Method for the Visualization of Novel High-Resolution Precision Photography and Micro-XCT Data Sets of NASA's Apollo Lunar Samples and Antarctic Meteorite Samples to Create Combined Research-Grade 3D Virtual Samples for the Benefit of Astromaterials Collections Conservation, Curation, Scientific Research and Education

    NASA Technical Reports Server (NTRS)

    Blumenfeld, E. H.; Evans, C. A.; Oshel, E. R.; Liddle, D. A.; Beaulieu, K.; Zeigler, R. A.; Hanna, R. D.; Ketcham, R. A.

    2016-01-01

    New technologies make possible the advancement of documentation and visualization practices that can enhance conservation and curation protocols for NASA's Astromaterials Collections. With increasing demands for accessibility to updated comprehensive data, and with new sample return missions on the horizon, it is of primary importance to develop new standards for contemporary documentation and visualization methodologies. Our interdisciplinary team has expertise in the fields of heritage conservation practices, professional photography, photogrammetry, imaging science, application engineering, data curation, geoscience, and astromaterials curation. Our objective is to create virtual 3D reconstructions of Apollo Lunar and Antarctic Meteorite samples that are a fusion of two state-of-the-art data sets: the interior view of the sample by collecting Micro-XCT data and the exterior view of the sample by collecting high-resolution precision photography data. These new data provide researchers an information-rich visualization of both compositional and textural information prior to any physical sub-sampling. Since January 2013 we have developed a process that resulted in the successful creation of the first image-based 3D reconstruction of an Apollo Lunar Sample correlated to a 3D reconstruction of the same sample's Micro- XCT data, illustrating that this technique is both operationally possible and functionally beneficial. In May of 2016 we began a 3-year research period during which we aim to produce Virtual Astromaterials Samples for 60 high-priority Apollo Lunar and Antarctic Meteorite samples and serve them on NASA's Astromaterials Acquisition and Curation website. Our research demonstrates that research-grade Virtual Astromaterials Samples are beneficial in preserving for posterity a precise 3D reconstruction of the sample prior to sub-sampling, which greatly improves documentation practices, provides unique and novel visualization of the sample's interior and exterior features, offers scientists a preliminary research tool for targeted sub-sample requests, and additionally is a visually engaging interactive tool for bringing astromaterials science to the public.

  10. An Interdisciplinary Method for the Visualization of Novel High-Resolution Precision Photography and Micro-XCT Data Sets of NASA's Apollo Lunar Samples and Antarctic Meteorite Samples to Create Combined Research-Grade 3D Virtual Samples for the Benefit of Astromaterials Collections Conservation, Curation, Scientific Research and Education

    NASA Astrophysics Data System (ADS)

    Blumenfeld, E. H.; Evans, C. A.; Zeigler, R. A.; Righter, K.; Beaulieu, K. R.; Oshel, E. R.; Liddle, D. A.; Hanna, R.; Ketcham, R. A.; Todd, N. S.

    2016-12-01

    New technologies make possible the advancement of documentation and visualization practices that can enhance conservation and curation protocols for NASA's Astromaterials Collections. With increasing demands for accessibility to updated comprehensive data, and with new sample return missions on the horizon, it is of primary importance to develop new standards for contemporary documentation and visualization methodologies. Our interdisciplinary team has expertise in the fields of heritage conservation practices, professional photography, photogrammetry, imaging science, application engineering, data curation, geoscience, and astromaterials curation. Our objective is to create virtual 3D reconstructions of Apollo Lunar and Antarctic Meteorite samples that are a fusion of two state-of-the-art data sets: the interior view of the sample by collecting Micro-XCT data and the exterior view of the sample by collecting high-resolution precision photography data. These new data provide researchers an information-rich visualization of both compositional and textural information prior to any physical sub-sampling. Since January 2013 we have developed a process that resulted in the successful creation of the first image-based 3D reconstruction of an Apollo Lunar Sample correlated to a 3D reconstruction of the same sample's Micro-XCT data, illustrating that this technique is both operationally possible and functionally beneficial. In May of 2016 we began a 3-year research period during which we aim to produce Virtual Astromaterials Samples for 60 high-priority Apollo Lunar and Antarctic Meteorite samples and serve them on NASA's Astromaterials Acquisition and Curation website. Our research demonstrates that research-grade Virtual Astromaterials Samples are beneficial in preserving for posterity a precise 3D reconstruction of the sample prior to sub-sampling, which greatly improves documentation practices, provides unique and novel visualization of the sample's interior and exterior features, offers scientists a preliminary research tool for targeted sub-sample requests, and additionally is a visually engaging interactive tool for bringing astromaterials science to the public.

  11. On the Usability and Usefulness of 3d (geo)visualizations - a Focus on Virtual Reality Environments

    NASA Astrophysics Data System (ADS)

    Çöltekin, A.; Lokka, I.; Zahner, M.

    2016-06-01

    Whether and when should we show data in 3D is an on-going debate in communities conducting visualization research. A strong opposition exists in the information visualization (Infovis) community, and seemingly unnecessary/unwarranted use of 3D, e.g., in plots, bar or pie charts, is heavily criticized. The scientific visualization (Scivis) community, on the other hand, is more supportive of the use of 3D as it allows `seeing' invisible phenomena, or designing and printing things that are used in e.g., surgeries, educational settings etc. Geographic visualization (Geovis) stands between the Infovis and Scivis communities. In geographic information science, most visuo-spatial analyses have been sufficiently conducted in 2D or 2.5D, including analyses related to terrain and much of the urban phenomena. On the other hand, there has always been a strong interest in 3D, with similar motivations as in Scivis community. Among many types of 3D visualizations, a popular one that is exploited both for visual analysis and visualization is the highly realistic (geo)virtual environments. Such environments may be engaging and memorable for the viewers because they offer highly immersive experiences. However, it is not yet well-established if we should opt to show the data in 3D; and if yes, a) what type of 3D we should use, b) for what task types, and c) for whom. In this paper, we identify some of the central arguments for and against the use of 3D visualizations around these three considerations in a concise interdisciplinary literature review.

  12. SU-D-12A-02: DeTECT, a Method to Enhance Soft Tissue Contrast From Mega Voltage CT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sheng, K; Gou, S; Qi, S

    Purpose: MVCT images have been used on TomoTherapy system to align patients based on bony anatomies but its usefulness for soft tissue registration, delineation and adaptive radiation therapy is severely limited due to minimal photoelectric interaction and prominent presence of noise resulting from low detector quantum efficiency of megavoltage x-rays. We aim to utilize a non-local means denoising method and texture analysis to recover the soft tissue information for MVCT. Methods: A block matching 3D (BM3D) algorithm was adapted to reduce the noise while keeping the texture information of the MVCT images. BM3D is an imaging denoising algorithm developed frommore » non-local means methods. BM3D additionally creates 3D groups by stacking 2D patches by the order of similarity. 3D denoising operation is then performed. The resultant 3D group is inversely transformed back to 2D images. In this study, BM3D was applied to MVCT images of a CT quality phantom, a head and neck and a prostate patient. Following denoising, imaging texture was enhanced to create the denoised and texture enhanced CT (DeTECT). Results: The original MVCT images show prevalent noise and poor soft tissue contrast. By applying BM3D denoising and texture enhancement, all MVCT images show remarkable improvements. For the phantom, the contrast to noise ratio for the low contrast plug was improved from 2.2 to 13.1 without compromising line pair conspicuity. For the head and neck patient, the lymph nodes and vein in the carotid space inconspicuous in the original MVCT image becomes highly visible in DeTECT. For the prostate patient, the boundary between the bladder and the prostate in the original MVCT is successfully recovered. Both results are visually validated by kVCT images of the corresponding patients. Conclusion: DeTECT showed the promise to drastically improve the soft tissue contrast of MVCT for image guided radiotherapy and adaptive radiotherapy.« less

  13. H-Ransac a Hybrid Point Cloud Segmentation Combining 2d and 3d Data

    NASA Astrophysics Data System (ADS)

    Adam, A.; Chatzilari, E.; Nikolopoulos, S.; Kompatsiaris, I.

    2018-05-01

    In this paper, we present a novel 3D segmentation approach operating on point clouds generated from overlapping images. The aim of the proposed hybrid approach is to effectively segment co-planar objects, by leveraging the structural information originating from the 3D point cloud and the visual information from the 2D images, without resorting to learning based procedures. More specifically, the proposed hybrid approach, H-RANSAC, is an extension of the well-known RANSAC plane-fitting algorithm, incorporating an additional consistency criterion based on the results of 2D segmentation. Our expectation that the integration of 2D data into 3D segmentation will achieve more accurate results, is validated experimentally in the domain of 3D city models. Results show that HRANSAC can successfully delineate building components like main facades and windows, and provide more accurate segmentation results compared to the typical RANSAC plane-fitting algorithm.

  14. Low agreement of visual rating for detailed quantification of pulmonary emphysema in whole-lung CT.

    PubMed

    Mascalchi, Mario; Diciotti, Stefano; Sverzellati, Nicola; Camiciottoli, Gianna; Ciccotosto, Cesareo; Falaschi, Fabio; Zompatori, Maurizio

    2012-02-01

    Multidetector spiral computed tomography (CT) has opened the possibility of quantitative evaluation of emphysema extent in the whole lung. Visual assessment can be used for such a purpose, but its reproducibility has not been established. To assess agreement of detailed assessment of pulmonary emphysema on whole-lung CT using a visual scale. Thirty patients with chronic obstructive pulmonary disease underwent whole-lung inspiratory CT. Four chest radiologists rated the same 22 ± 2 thin sections using a visual scale which defines a range of emphysema extent between 0 and 100. Two of them repeated the rating two months later. Inter- and intra-operator agreement was evaluated with the Bland and Altman method. In addition, the percentage of emphysema at -950 Hounsfield units in the whole lung was determined using fully automated commercially available software for 3D densitometry. In three of six operator pairs and in one of two intra-operator pairs the Kendall τ test showed a significant correlation between the difference and the average magnitude of visual scores. Among different operators the half-width of 95% limits of agreement (95% LoA) was wide ranging between a score of 14.2-27.7 for an average visual score of 20 and between 18.5-36.8 for an average visual score of 80. Within the same operator the half-width of 95% LoA ranged between a score of 10.9-21.0 for an average visual score of 20 and between 25.1-30.1 for an average visual score of 80. The visual scores of the four radiologists were correlated with the results of densitometry (P < 0.001; r = 0.65-0.81). The inter- and intra-operator agreement of detailed assessment of emphysema in the whole lung using a visual scale is low and decreases with increasing emphysema extent.

  15. FROMS3D: New Software for 3-D Visualization of Fracture Network System in Fractured Rock Masses

    NASA Astrophysics Data System (ADS)

    Noh, Y. H.; Um, J. G.; Choi, Y.

    2014-12-01

    A new software (FROMS3D) is presented to visualize fracture network system in 3-D. The software consists of several modules that play roles in management of borehole and field fracture data, fracture network modelling, visualization of fracture geometry in 3-D and calculation and visualization of intersections and equivalent pipes between fractures. Intel Parallel Studio XE 2013, Visual Studio.NET 2010 and the open source VTK library were utilized as development tools to efficiently implement the modules and the graphical user interface of the software. The results have suggested that the developed software is effective in visualizing 3-D fracture network system, and can provide useful information to tackle the engineering geological problems related to strength, deformability and hydraulic behaviors of the fractured rock masses.

  16. On the comparison of visual discomfort generated by S3D and 2D content based on eye-tracking features

    NASA Astrophysics Data System (ADS)

    Iatsun, Iana; Larabi, Mohamed-Chaker; Fernandez-Maloigne, Christine

    2014-03-01

    The changing of TV systems from 2D to 3D mode is the next expected step in the telecommunication world. Some works have already been done to perform this progress technically, but interaction of the third dimension with humans is not yet clear. Previously, it was found that any increased load of visual system can create visual fatigue, like prolonged TV watching, computer work or video gaming. But watching S3D can cause another nature of visual fatigue, since all S3D technologies creates illusion of the third dimension based on characteristics of binocular vision. In this work we propose to evaluate and compare the visual fatigue from watching 2D and S3D content. This work shows the difference in accumulation of visual fatigue and its assessment for two types of content. In order to perform this comparison eye-tracking experiments using six commercially available movies were conducted. Healthy naive participants took part into the test and gave their answers feeling the subjective evaluation. It was found that watching stereo 3D content induce stronger feeling of visual fatigue than conventional 2D, and the nature of video has an important effect on its increase. Visual characteristics obtained by using eye-tracking were investigated regarding their relation with visual fatigue.

  17. Finite field equation of Yang--Mills theory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brandt, R.A.; Wing-Chiu, N.; Yeung, W.

    1980-03-01

    We consider the finite local field equation -)(1+1/..cap alpha.. (1+f/sub 4/))g/sup munu/D'Alembertian-partial/sup ..mu../partial/sup ..nu../)A/sup nua/ =-(1+f/sub 3/) g/sup 2/N(A/sup c/..nu..A/sup a/..mu..A/sub ..nu..//sup c/) +xxx+(1-s)/sup 2/M/sup 2/A/sup a/..mu.., introduced by Lowenstein to rigorously describe SU(2) Yang--Mills theory, which is written in terms of normal products. We also consider the operator product expansion A/sup c/..nu..(x+xi) A/sup a/..mu..(x) A/sup b/lambda(x-xi) approx...sigma..M/sup c/ab..nu mu..lambda/sub c/'a'b'..nu..'..mu..'lambda' (xi) N(A/sup nuprimec/'A/sup muprimea/'A/sup lambdaprimeb/')(x), and using asymptotic freedom, we compute the leading behavior of the Wilson coefficients M/sup ...//sub .../(xi) with the help of a computer, and express the normal products in the field equation in terms ofmore » products of the c-number Wilson coefficients and of operator products like A/sup c/..nu..(x+xi) A/sup a/..mu..(x) A/sup b/lambda(x-xi) at separated points. Our result is -)(1+(1/..cap alpha..)(1+f/sub 4/))g/sup munu/D'Alembertian-partial/sup ..mu../partial/sup ..nu../)A/sup nua/ =-(1+f/sub 3/) g/sup 2/lim/sub xiarrow-right0/) (lnxi)/sup -0.28/2b/(A/sup c/..nu.. (x+xi) A/sup a/..mu..(x) A/sub ..nu..//sup c/(x-xi) +epsilon/sup a/bcA/sup muc/(x+xi) partial/sup ..nu../A/sup b//sub ..nu../(x)+xxx) +xxx)+(1-s)/sup 2/M/sup 2/A/sup a/..mu.., where ..beta.. (g) =-bg/sup 3/, and so (lnxi)/sup -0.28/2b/ is the leading behavior of the c-number coefficient multiplying the operator products in the field equation.« less

  18. Real-time image-guided nasogastric feeding tube placement: A case series using Kangaroo with IRIS Technology in an ICU.

    PubMed

    Mizzi, Anna; Cozzi, Silvano; Beretta, Luigi; Greco, Massimiliano; Braga, Marco

    2017-05-01

    Pulmonary misplacement during the blind insertion of enteral feeding tubes is frequent, particularly in ventilated and neurologically impaired patients. This is probably the first clinical study using the Kangaroo Feeding Tube with IRIS technology (IRIS) which incorporates a camera designed to provide anatomic landmark visualization during insertion. The study aim was to evaluate IRIS performance during bedside gastric placement. This is the first prospective study to collect data on the use of IRIS. Twenty consecutive unconscious patients requiring enteral nutrition were recruited at a single center. IRIS placement was considered complete when a clear image of the gastric mucosa appeared. Correct placement was confirmed using a contrast-enhanced abdominal X-ray. To evaluate the device performance over time, the camera was activated every other day up to 17 d postplacement. In 7 (35%) patients, the trachea was initially visualized, requiring a second placement attempt with the same tube. The IRIS camera allowed recognition of the gastric mucosa in 18 (90%) patients. The esophagogastric junction was identified in one patient, while in a second patient the quality of visualization was poor. Contrast-enhanced X-ray confirmed the gastric placement of IRIS in all patients. IRIS allowed identification of gastric mucosa in 14 (70%) patients 3 d after placement. Performance progressively declined with time (P = 0.006, chi-square for trend). IRIS placement could have spared X-ray confirmation in almost all patients and prevented misplacement into the airway in about one third. Visualization quality needs to be improved, particularly after the first week. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. High-resolution three-dimensional visualization of the rat spinal cord microvasculature by synchrotron radiation micro-CT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hu, Jianzhong; Cao, Yong; Wu, Tianding

    2014-10-15

    Purpose: Understanding the three-dimensional (3D) morphology of the spinal cord microvasculature has been limited by the lack of an effective high-resolution imaging technique. In this study, synchrotron radiation microcomputed tomography (SRµCT), a novel imaging technique based on absorption imaging, was evaluated with regard to the detection of the 3D morphology of the rat spinal cord microvasculature. Methods: Ten Sprague-Dawley rats were used in this ex vivo study. After contrast agent perfusion, their spinal cords were isolated and scanned using conventional x-rays, conventional micro-CT (CµCT), and SRµCT. Results: Based on contrast agent perfusion, the microvasculature of the rat spinal cord wasmore » clearly visualized for the first time ex vivo in 3D by means of SRµCT scanning. Compared to conventional imaging techniques, SRµCT achieved higher resolution 3D vascular imaging, with the smallest vessel that could be distinguished approximately 7.4 μm in diameter. Additionally, a 3D pseudocolored image of the spinal cord microvasculature was generated in a single session of SRµCT imaging, which was conducive to detailed observation of the vessel morphology. Conclusions: The results of this study indicated that SRµCT scanning could provide higher resolution images of the vascular network of the spinal cord. This modality also has the potential to serve as a powerful imaging tool for the investigation of morphology changes in the 3D angioarchitecture of the neurovasculature in preclinical research.« less

  20. Optical Enhancement of Degraded Fingerprints.

    DTIC Science & Technology

    1986-05-01

    system. The integral 00 g(x,y) = ff f ( Cn)h(x-C,y-n)d dn -00 is the convolution operation g(x,y)=f(x,y)*h(x,y) where h(x,y) is the impulse response...periodic ridges on the left (1-) and right (2--) sides of the fingerprint in Figure 3-1 as periodic impulse -sheets (an impulse -sheet is a one...transformation of uniformly spaced, parallel impulse -sheets is a string of impulses (an impulse is a two-dimensional Dirac delta function, i.e. f(x,y) = 6(x,y

  1. Fundamentals and recent advances in X-ray micro computed tomography (microCT) applied on thermal-fluid dynamics and multiphase flows

    NASA Astrophysics Data System (ADS)

    Santini, Maurizio

    2015-11-01

    X-ray computed tomography (CT) is a well-known technique nowadays, since its first practical application by Sir. G. Hounsfield (Nobel price for medicine 1979) has continually benefited from optimising improvements, especially in medical applications. Indeed, also application of CT in various engineering research fields provides fundamental informations on a wide range of applications, considering that the technique is not destructive, allowing 3D visualization without perturbation of the analysed material. Nowadays, it is technologically possible to design and realize an equipment that achieve a micrometric resolution and even improve the sensibility in revealing differences in materials having very radiotransparency, allowing i.e. to distinguish between different fluids (with different density) or states of matter (like with two-phase flows). At the University of Bergamo, a prototype of an X-ray microCT system was developed since 2008, so being fully operative from 2012, with specific customizations for investigations in thermal-fluid dynamics and multiphase flow researches. A technical session held at the UIT International Conference in L'Aquila (Italy), at which this paper is referring, has presented some microCT fundamentals, to allow the audience to gain basics to follow the “fil-rouge” that links all the instrumentation developments, till the recent applications. Hereinafter are reported some applications currently developed at Bergamo University at the X-ray computed micro-tomography laboratory.

  2. Flicker-defined form perimetry in glaucoma patients.

    PubMed

    Horn, Folkert K; Kremers, Jan; Mardin, Christian Y; Jünemann, Anselm G; Adler, Werner; Tornow, Ralf P

    2015-03-01

    To assess the potential of flicker-defined form (FDF) perimetry to detect functional loss in patient groups with beginning glaucoma, and to evaluate the dynamic range of the FDF stimulus in individual patients and at individual test positions. FDF perimetry and standard automated perimetry (SAP) were performed at identical test locations (adapted G1 protocol) in 60 healthy subjects and 111 glaucoma patients. All patients showed glaucomatous optic disc appearance. Grouping within the glaucoma cohort was based on SAP-performance: 33 "preperimetric" open-angle glaucoma (OAG) patients, 28 "borderline" OAG (focal defects and SAP-mean defect (MD) <2 dB), 33 "early" OAG (SAP-MD < 5 dB), 17 "advanced" OAG. All participants were experienced in psychophysical and perimetric tests. Defect values and the areas under receiver operating characteristic curves (ROC) in patient groups were statistically compared. The values of FDF-MD in the preperimetric, borderline, and early OAG group were 2.7 ± 3.4 dB, 5.5 ± 2.6 dB, and 8.5 ± 3.4 dB respectively (all significantly above normal). The percentage of patients exceeding normal FDF-MD was 27.3 %, 60.7 %, and 87.9 % respectively. The age-adjusted FDF-mean defect (MD) of the G1X-protocol was not significantly correlated with refractive error, lens opacity, pupil size, or gender. Occurrence of ceiling effects (inability to detect targets at highest contrast) showed a high correlation with visual field losses (R = 0.72, p < 0.001). Local analysis indicates that SAP losses exceeding 5 dB could not be distinguished with the FDF technique. The FDF stimulus was able to detect beginning glaucoma damage. Patients with SAP-MD values exceeding 5 dB should be monitored with conventional perimetry because of its larger dynamic range.

  3. X-ray mosaic nanotomography of large microorganisms.

    PubMed

    Mokso, R; Quaroni, L; Marone, F; Irvine, S; Vila-Comamala, J; Blanke, A; Stampanoni, M

    2012-02-01

    Full-field X-ray microscopy is a valuable tool for 3D observation of biological systems. In the soft X-ray domain organelles can be visualized in individual cells while hard X-ray microscopes excel in imaging of larger complex biological tissue. The field of view of these instruments is typically 10(3) times the spatial resolution. We exploit the assets of the hard X-ray sub-micrometer imaging and extend the standard approach by widening the effective field of view to match the size of the sample. We show that global tomography of biological systems exceeding several times the field of view is feasible also at the nanoscale with moderate radiation dose. We address the performance issues and limitations of the TOMCAT full-field microscope and more generally for Zernike phase contrast imaging. Two biologically relevant systems were investigated. The first being the largest known bacteria (Thiomargarita namibiensis), the second is a small myriapod species (Pauropoda sp.). Both examples illustrate the capacity of the unique, structured condenser based broad-band full-field microscope to access the 3D structural details of biological systems at the nanoscale while avoiding complicated sample preparation, or even keeping the sample environment close to the natural state. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. The Limits of Shape Recognition following Late Emergence from Blindness.

    PubMed

    McKyton, Ayelet; Ben-Zion, Itay; Doron, Ravid; Zohary, Ehud

    2015-09-21

    Visual object recognition develops during the first years of life. But what if one is deprived of vision during early post-natal development? Shape information is extracted using both low-level cues (e.g., intensity- or color-based contours) and more complex algorithms that are largely based on inference assumptions (e.g., illumination is from above, objects are often partially occluded). Previous studies, testing visual acuity using a 2D shape-identification task (Lea symbols), indicate that contour-based shape recognition can improve with visual experience, even after years of visual deprivation from birth. We hypothesized that this may generalize to other low-level cues (shape, size, and color), but not to mid-level functions (e.g., 3D shape from shading) that might require prior visual knowledge. To that end, we studied a unique group of subjects in Ethiopia that suffered from an early manifestation of dense bilateral cataracts and were surgically treated only years later. Our results suggest that the newly sighted rapidly acquire the ability to recognize an odd element within an array, on the basis of color, size, or shape differences. However, they are generally unable to find the odd shape on the basis of illusory contours, shading, or occlusion relationships. Little recovery of these mid-level functions is seen within 1 year post-operation. We find that visual performance using low-level cues is relatively robust to prolonged deprivation from birth. However, the use of pictorial depth cues to infer 3D structure from the 2D retinal image is highly susceptible to early and prolonged visual deprivation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. X-ray and optical stereo-based 3D sensor fusion system for image-guided neurosurgery.

    PubMed

    Kim, Duk Nyeon; Chae, You Seong; Kim, Min Young

    2016-04-01

    In neurosurgery, an image-guided operation is performed to confirm that the surgical instruments reach the exact lesion position. Among the multiple imaging modalities, an X-ray fluoroscope mounted on C- or O-arm is widely used for monitoring the position of surgical instruments and the target position of the patient. However, frequently used fluoroscopy can result in relatively high radiation doses, particularly for complex interventional procedures. The proposed system can reduce radiation exposure and provide the accurate three-dimensional (3D) position information of surgical instruments and the target position. X-ray and optical stereo vision systems have been proposed for the C- or O-arm. Two subsystems have same optical axis and are calibrated simultaneously. This provides easy augmentation of the camera image and the X-ray image. Further, the 3D measurement of both systems can be defined in a common coordinate space. The proposed dual stereoscopic imaging system is designed and implemented for mounting on an O-arm. The calibration error of the 3D coordinates of the optical stereo and X-ray stereo is within 0.1 mm in terms of the mean and the standard deviation. Further, image augmentation with the camera image and the X-ray image using an artificial skull phantom is achieved. As the developed dual stereoscopic imaging system provides 3D coordinates of the point of interest in both optical images and fluoroscopic images, it can be used by surgeons to confirm the position of surgical instruments in a 3D space with minimum radiation exposure and to verify whether the instruments reach the surgical target observed in fluoroscopic images.

  6. In vivo evaluation of inter-operator reproducibility of digital dental and conventional impression techniques

    PubMed Central

    Kamimura, Emi; Tanaka, Shinpei; Takaba, Masayuki; Tachi, Keita; Baba, Kazuyoshi

    2017-01-01

    Purpose The aim of this study was to evaluate and compare the inter-operator reproducibility of three-dimensional (3D) images of teeth captured by a digital impression technique to a conventional impression technique in vivo. Materials and methods Twelve participants with complete natural dentition were included in this study. A digital impression of the mandibular molars of these participants was made by two operators with different levels of clinical experience, 3 or 16 years, using an intra-oral scanner (Lava COS, 3M ESPE). A silicone impression also was made by the same operators using the double mix impression technique (Imprint3, 3M ESPE). Stereolithography (STL) data were directly exported from the Lava COS system, while STL data of a plaster model made from silicone impression were captured by a three-dimensional (3D) laboratory scanner (D810, 3shape). The STL datasets recorded by two different operators were compared using 3D evaluation software and superimposed using the best-fit-algorithm method (least-squares method, PolyWorks, InnovMetric Software) for each impression technique. Inter-operator reproducibility as evaluated by average discrepancies of corresponding 3D data was compared between the two techniques (Wilcoxon signed-rank test). Results The visual inspection of superimposed datasets revealed that discrepancies between repeated digital impression were smaller than observed with silicone impression. Confirmation was forthcoming from statistical analysis revealing significantly smaller average inter-operator reproducibility using a digital impression technique (0.014± 0.02 mm) than when using a conventional impression technique (0.023 ± 0.01 mm). Conclusion The results of this in vivo study suggest that inter-operator reproducibility with a digital impression technique may be better than that of a conventional impression technique and is independent of the clinical experience of the operator. PMID:28636642

  7. Convergence Acceleration for Multistage Time-Stepping Schemes

    NASA Technical Reports Server (NTRS)

    Swanson, R. C.; Turkel, Eli L.; Rossow, C-C; Vasta, V. N.

    2006-01-01

    The convergence of a Runge-Kutta (RK) scheme with multigrid is accelerated by preconditioning with a fully implicit operator. With the extended stability of the Runge-Kutta scheme, CFL numbers as high as 1000 could be used. The implicit preconditioner addresses the stiffness in the discrete equations associated with stretched meshes. Numerical dissipation operators (based on the Roe scheme, a matrix formulation, and the CUSP scheme) as well as the number of RK stages are considered in evaluating the RK/implicit scheme. Both the numerical and computational efficiency of the scheme with the different dissipation operators are discussed. The RK/implicit scheme is used to solve the two-dimensional (2-D) and three-dimensional (3-D) compressible, Reynolds-averaged Navier-Stokes equations. In two dimensions, turbulent flows over an airfoil at subsonic and transonic conditions are computed. The effects of mesh cell aspect ratio on convergence are investigated for Reynolds numbers between 5.7 x 10(exp 6) and 100.0 x 10(exp 6). Results are also obtained for a transonic wing flow. For both 2-D and 3-D problems, the computational time of a well-tuned standard RK scheme is reduced at least a factor of four.

  8. Femtosecond visualization of lattice dynamics in shock-compressed matter.

    PubMed

    Milathianaki, D; Boutet, S; Williams, G J; Higginbotham, A; Ratner, D; Gleason, A E; Messerschmidt, M; Seibert, M M; Swift, D C; Hering, P; Robinson, J; White, W E; Wark, J S

    2013-10-11

    The ultrafast evolution of microstructure is key to understanding high-pressure and strain-rate phenomena. However, the visualization of lattice dynamics at scales commensurate with those of atomistic simulations has been challenging. Here, we report femtosecond x-ray diffraction measurements unveiling the response of copper to laser shock-compression at peak normal elastic stresses of ~73 gigapascals (GPa) and strain rates of 10(9) per second. We capture the evolution of the lattice from a one-dimensional (1D) elastic to a 3D plastically relaxed state within a few tens of picoseconds, after reaching shear stresses of 18 GPa. Our in situ high-precision measurement of material strength at spatial (<1 micrometer) and temporal (<50 picoseconds) scales provides a direct comparison with multimillion-atom molecular dynamics simulations.

  9. Geometric modeling of hepatic arteries in 3D ultrasound with unsupervised MRA fusion during liver interventions.

    PubMed

    Gérard, Maxime; Michaud, François; Bigot, Alexandre; Tang, An; Soulez, Gilles; Kadoury, Samuel

    2017-06-01

    Modulating the chemotherapy injection rate with regard to blood flow velocities in the tumor-feeding arteries during intra-arterial therapies may help improve liver tumor targeting while decreasing systemic exposure. These velocities can be obtained noninvasively using Doppler ultrasound (US). However, small vessels situated in the liver are difficult to identify and follow in US. We propose a multimodal fusion approach that non-rigidly registers a 3D geometric mesh model of the hepatic arteries obtained from preoperative MR angiography (MRA) acquisitions with intra-operative 3D US imaging. The proposed fusion tool integrates 3 imaging modalities: an arterial MRA, a portal phase MRA and an intra-operative 3D US. Preoperatively, the arterial phase MRA is used to generate a 3D model of the hepatic arteries, which is then non-rigidly co-registered with the portal phase MRA. Once the intra-operative 3D US is acquired, we register it with the portal MRA using a vessel-based rigid initialization followed by a non-rigid registration using an image-based metric based on linear correlation of linear combination. Using the combined non-rigid transformation matrices, the 3D mesh model is fused with the 3D US. 3D US and multi-phase MRA images acquired from 10 porcine models were used to test the performance of the proposed fusion tool. Unimodal registration of the MRA phases yielded a target registration error (TRE) of [Formula: see text] mm. Initial rigid alignment of the portal MRA and 3D US yielded a mean TRE of [Formula: see text] mm, which was significantly reduced to [Formula: see text] mm ([Formula: see text]) after affine image-based registration. The following deformable registration step allowed for further decrease of the mean TRE to [Formula: see text] mm. The proposed tool could facilitate visualization and localization of these vessels when using 3D US intra-operatively for either intravascular or percutaneous interventions to avoid vessel perforation.

  10. Integration by parts and Pohozaev identities for space-dependent fractional-order operators

    NASA Astrophysics Data System (ADS)

    Grubb, Gerd

    2016-08-01

    Consider a classical elliptic pseudodifferential operator P on Rn of order 2a (0 < a < 1) with even symbol. For example, P = A(x , D) a where A (x , D) is a second-order strongly elliptic differential operator; the fractional Laplacian (- Δ) a is a particular case. For solutions u of the Dirichlet problem on a bounded smooth subset Ω ⊂Rn, we show an integration-by-parts formula with a boundary integral involving (d-a u)|∂Ω, where d (x) = dist (x , ∂ Ω). This extends recent results of Ros-Oton, Serra and Valdinoci, to operators that are x-dependent, nonsymmetric, and have lower-order parts. We also generalize their formula of Pohozaev-type, that can be used to prove unique continuation properties, and nonexistence of nontrivial solutions of semilinear problems. An illustration is given with P =(- Δ +m2) a. The basic step in our analysis is a factorization of P, P ∼P-P+, where we set up a calculus for the generalized pseudodifferential operators P± that come out of the construction.

  11. STARE CubeSat Communications Testing, Simulation and Analysis

    DTIC Science & Technology

    2012-09-01

    26  Figure 24.  STK MC3 Ground Station Locations ................................................... 31  x THIS PAGE INTENTIONALLY LEFT BLANK xi...Refinement of Ephemeris STK Satellite Tool Kit VPN Virtual Private Network xiv THIS PAGE INTENTIONALLY LEFT BLANK xv ACKNOWLEDGMENTS This...the radio itself. Using a signal attenuator to decrease signal strength by 10 dB increments, and a spectrum analyzer to see a visual representation

  12. Noninvasive 3D Visualization of Defects and Crack Propagation in Layered Foam Structures by Phase Contrast Microimaging

    NASA Technical Reports Server (NTRS)

    Hu, Z. W.; DeCarlo, F.

    2006-01-01

    Applications of polymeric foams in our modern society continue to grow because of their light weight, high strength, excellent thermal and mechanical insulation, and the ease of engineering. Among others, closed-cell foam has been structurally used for thermally insulating the shuttle external tank. However, internal defects of the foams were difficult to observe non-invasively due to limited sensitivity to the low-density structures possessed by traditional imaging tools such as computed X-ray tomography By combining phase contrast X-ray imaging with pressure loading, we succeeded in precisely mapping intact cellular structure and defects inside the bulk of layered foam and visualizing its subsequent response to the pressure in three-dimensional space. The work demonstrated a powerfir1 approach for yielding insight into underlying problems in lightweight cellular materials otherwise unobtainable.

  13. Forecasting the ocean optical environment in support of Navy mine warfare operations

    NASA Astrophysics Data System (ADS)

    Ladner, S. D.; Arnone, R.; Jolliff, J.; Casey, B.; Matulewski, K.

    2012-06-01

    A 3D ocean optical forecast system called TODS (Tactical Ocean Data System) has been developed to determine the performance of underwater LIDAR detection/identification systems. TODS fuses optical measurements from gliders, surface satellite optical properties, and 3D ocean forecast circulation models to extend the 2-dimensional surface satellite optics into a 3-dimensional optical volume including subsurface optical layers of beam attenuation coefficient (c) and diver visibility. Optical 3D nowcast and forecasts are combined with electro-optical identification (EOID) models to determine the underwater LIDAR imaging performance field used to identify subsurface mine threats in rapidly changing coastal regions. TODS was validated during a recent mine warfare exercise with Helicopter Mine Countermeasures Squadron (HM-14). Results include the uncertainties in the optical forecast and lidar performance and sensor tow height predictions that are based on visual detection and identification metrics using actual mine target images from the EOID system. TODS is a new capability of coupling the 3D optical environment and EOID system performance and is proving important for the MIW community as both a tactical decision aid and for use in operational planning, improving timeliness and efficiency in clearance operations.

  14. Value of 3D printing for the comprehension of surgical anatomy.

    PubMed

    Marconi, Stefania; Pugliese, Luigi; Botti, Marta; Peri, Andrea; Cavazzi, Emma; Latteri, Saverio; Auricchio, Ferdinando; Pietrabissa, Andrea

    2017-10-01

    In a preliminary experience, we claimed the potential value of 3D printing technology for pre-operative counseling and surgical planning. However, no objective analysis has ever assessed its additional benefit in transferring anatomical information from radiology to final users. We decided to validate the pre-operative use of 3D-printed anatomical models in patients with solid organs' diseases as a new tool to deliver morphological information. Fifteen patients scheduled for laparoscopic splenectomy, nephrectomy, or pancreatectomy were selected and, for each, a full-size 3D virtual anatomical object was reconstructed from a contrast-enhanced MDCT (Multiple Detector Computed Tomography) and then prototyped using a 3D printer. After having carefully evaluated-in a random sequence-conventional contrast MDCT scans, virtual 3D reconstructions on a flat monitor, and 3D-printed models of the same anatomy for each selected case, thirty subjects with different expertise in radiological imaging (10 medical students, 10 surgeons and 10 radiologists) were administered a multiple-item questionnaire. Crucial issues for the anatomical understanding and the pre-operative planning of the scheduled procedure were addressed. The visual and tactile inspection of 3D models allowed the best anatomical understanding, with faster and clearer comprehension of the surgical anatomy. As expected, less experienced medical students perceived the highest benefit (53.9% ± 4.14 of correct answers with 3D-printed models, compared to 53.4 % ± 4.6 with virtual models and 45.5% ± 4.6 with MDCT), followed by surgeons and radiologists. The average time spent by participants in 3D model assessing was shorter (60.67 ± 25.5 s) than the one of the corresponding virtual 3D reconstruction (70.8 ± 28.18 s) or conventional MDCT scan (127.04 ± 35.91 s). 3D-printed models help to transfer complex anatomical information to clinicians, resulting useful in the pre-operative planning, for intra-operative navigation and for surgical training purposes.

  15. Nebula: reconstruction and visualization of scattering data in reciprocal space.

    PubMed

    Reiten, Andreas; Chernyshov, Dmitry; Mathiesen, Ragnvald H

    2015-04-01

    Two-dimensional solid-state X-ray detectors can now operate at considerable data throughput rates that allow full three-dimensional sampling of scattering data from extended volumes of reciprocal space within second to minute time-scales. For such experiments, simultaneous analysis and visualization allows for remeasurements and a more dynamic measurement strategy. A new software, Nebula , is presented. It efficiently reconstructs X-ray scattering data, generates three-dimensional reciprocal space data sets that can be visualized interactively, and aims to enable real-time processing in high-throughput measurements by employing parallel computing on commodity hardware.

  16. Nebula: reconstruction and visualization of scattering data in reciprocal space

    PubMed Central

    Reiten, Andreas; Chernyshov, Dmitry; Mathiesen, Ragnvald H.

    2015-01-01

    Two-dimensional solid-state X-ray detectors can now operate at considerable data throughput rates that allow full three-dimensional sampling of scattering data from extended volumes of reciprocal space within second to minute time­scales. For such experiments, simultaneous analysis and visualization allows for remeasurements and a more dynamic measurement strategy. A new software, Nebula, is presented. It efficiently reconstructs X-ray scattering data, generates three-dimensional reciprocal space data sets that can be visualized interactively, and aims to enable real-time processing in high-throughput measurements by employing parallel computing on commodity hardware. PMID:25844083

  17. Comparison of 3D reconstruction of mandible for pre-operative planning using commercial and open-source software

    NASA Astrophysics Data System (ADS)

    Abdullah, Johari Yap; Omar, Marzuki; Pritam, Helmi Mohd Hadi; Husein, Adam; Rajion, Zainul Ahmad

    2016-12-01

    3D printing of mandible is important for pre-operative planning, diagnostic purposes, as well as for education and training. Currently, the processing of CT data is routinely performed with commercial software which increases the cost of operation and patient management for a small clinical setting. Usage of open-source software as an alternative to commercial software for 3D reconstruction of the mandible from CT data is scarce. The aim of this study is to compare two methods of 3D reconstruction of the mandible using commercial Materialise Mimics software and open-source Medical Imaging Interaction Toolkit (MITK) software. Head CT images with a slice thickness of 1 mm and a matrix of 512x512 pixels each were retrieved from the server located at the Radiology Department of Hospital Universiti Sains Malaysia. The CT data were analysed and the 3D models of mandible were reconstructed using both commercial Materialise Mimics and open-source MITK software. Both virtual 3D models were saved in STL format and exported to 3matic and MeshLab software for morphometric and image analyses. Both models were compared using Wilcoxon Signed Rank Test and Hausdorff Distance. No significant differences were obtained between the 3D models of the mandible produced using Mimics and MITK software. The 3D model of the mandible produced using MITK open-source software is comparable to the commercial MIMICS software. Therefore, open-source software could be used in clinical setting for pre-operative planning to minimise the operational cost.

  18. HECTOR: A 240kV micro-CT setup optimized for research

    NASA Astrophysics Data System (ADS)

    Masschaele, Bert; Dierick, Manuel; Van Loo, Denis; Boone, Matthieu N.; Brabant, Loes; Pauwels, Elin; Cnudde, Veerle; Van Hoorebeke, Luc

    2013-10-01

    X-ray micro-CT has become a very powerful and common tool for non-destructive three-dimensional (3D) visualization and analysis of objects. Many systems are commercially available, but they are typically limited in terms of operational freedom both from a mechanical point of view as well as for acquisition routines. HECTOR is the latest system developed by the Ghent University Centre for X-ray Tomography (http://www.ugct.ugent.be) in collaboration with X-Ray Engineering (XRE bvba, Ghent, Belgium). It consists of a mechanical setup with nine motorized axes and a modular acquisition software package and combines a microfocus directional target X-ray source up to 240 kV with a large flat-panel detector. Provisions are made to install a line-detector for a maximal operational range. The system can accommodate samples up to 80 kg, 1 m long and 80 cm in diameter while it is also suited for high resolution (down to 4 μm) tomography. The bi-directional detector tiling is suited for large samples while the variable source-detector distance optimizes the signal to noise ratio (SNR) for every type of sample, even with peripheral equipment such as compression stages or climate chambers. The large vertical travel of 1 m can be used for helical scanning and a vertical detector rotation axis allows laminography experiments. The setup is installed in a large concrete bunker to allow accommodation of peripheral equipment such as pumps, chillers, etc., which can be integrated in the modular acquisition software to obtain a maximal correlation between the environmental control and the CT data taken. The acquisition software does not only allow good coupling with the peripheral equipment but its scripting feature is also particularly interesting for testing new and exotic acquisition routines.

  19. 3D visualization of membrane failures in fuel cells

    NASA Astrophysics Data System (ADS)

    Singh, Yadvinder; Orfino, Francesco P.; Dutta, Monica; Kjeang, Erik

    2017-03-01

    Durability issues in fuel cells, due to chemical and mechanical degradation, are potential impediments in their commercialization. Hydrogen leak development across degraded fuel cell membranes is deemed a lifetime-limiting failure mode and potential safety issue that requires thorough characterization for devising effective mitigation strategies. The scope and depth of failure analysis has, however, been limited by the 2D nature of conventional imaging. In the present work, X-ray computed tomography is introduced as a novel, non-destructive technique for 3D failure analysis. Its capability to acquire true 3D images of membrane damage is demonstrated for the very first time. This approach has enabled unique and in-depth analysis resulting in novel findings regarding the membrane degradation mechanism; these are: significant, exclusive membrane fracture development independent of catalyst layers, localized thinning at crack sites, and demonstration of the critical impact of cracks on fuel cell durability. Evidence of crack initiation within the membrane is demonstrated, and a possible new failure mode different from typical mechanical crack development is identified. X-ray computed tomography is hereby established as a breakthrough approach for comprehensive 3D characterization and reliable failure analysis of fuel cell membranes, and could readily be extended to electrolyzers and flow batteries having similar structure.

  20. 3D Pathology Volumetric Technique: A Method for Calculating Breast Tumour Volume from Whole-Mount Serial Section Images

    PubMed Central

    Clarke, G. M.; Murray, M.; Holloway, C. M. B.; Liu, K.; Zubovits, J. T.; Yaffe, M. J.

    2012-01-01

    Tumour size, most commonly measured by maximum linear extent, remains a strong predictor of survival in breast cancer. Tumour volume, proportional to the number of tumour cells, may be a more accurate surrogate for size. We describe a novel “3D pathology volumetric technique” for lumpectomies and compare it with 2D measurements. Volume renderings and total tumour volume are computed from digitized whole-mount serial sections using custom software tools. Results are presented for two lumpectomy specimens selected for tumour features which may challenge accurate measurement of tumour burden with conventional, sampling-based pathology: (1) an infiltrative pattern admixed with normal breast elements; (2) a localized invasive mass separated from the in situ component by benign tissue. Spatial relationships between key features (tumour foci, close or involved margins) are clearly visualized in volume renderings. Invasive tumour burden can be underestimated using conventional pathology, compared to the volumetric technique (infiltrative pattern: 30% underestimation; localized mass: 3% underestimation for invasive tumour, 44% for in situ component). Tumour volume approximated from 2D measurements (i.e., maximum linear extent), assuming elliptical geometry, was seen to overestimate volume compared to the 3D volumetric calculation (by a factor of 7x for the infiltrative pattern; 1.5x for the localized invasive mass). PMID:23320179

  1. 3D Plenoptic PIV Measurements of a Shock Wave Boundary Layer Interaction

    NASA Astrophysics Data System (ADS)

    Thurow, Brian; Bolton, Johnathan; Arora, Nishul; Alvi, Farrukh

    2016-11-01

    Plenoptic particle image velocimetry (PIV) is a relatively new technique that uses the computational refocusing capability of a single plenoptic camera and volume illumination with a double-pulsed light source to measure the instantaneous 3D/3C velocity field of a flow field seeded with particles. In this work, plenoptic PIV is used to perform volumetric velocity field measurements of a shock-wave turbulent boundary layer interaction (SBLI). Experiments were performed in a Mach 2.0 flow with the SBLI produced by an unswept fin at 15°angle of attack. The measurement volume was 38 x 25 x 32 mm3 and illuminated with a 400 mJ/pulse Nd:YAG laser with 1.7 microsecond inter-pulse time. Conventional planar PIV measurements along two planes within the volume are used for comparison. 3D visualizations of the fin generated shock and subsequent SBLI are presented. The growth of the shock foot and separation region with increasing distance from the fin tip is observed and agrees with observations made using planar PIV. Instantaneous images depict 3D fluctuations in the position of the shock foot from one image to the next. The authors acknowledge the support of the Air Force Office of Scientific Research.

  2. Characteristic of x-ray tomography performance using CdTe timepix detector

    NASA Astrophysics Data System (ADS)

    Zain, R. M.; O'Shea, V.; Maneuski, D.

    2017-01-01

    X-ray Computed Tomography (CT) is a non-destructive technique for visualizing interior features within solid objects, and for obtaining digital information on their 3-D geometries and properties. The selection of CdTe Timepix detector has a sufficient performance of imaging detector is based on quality of detector performance and energy resolution. The study of Modulation Transfer Function (MTF) shows a 70% contrast at 4 lp/mm was achieved for the 55 µm pixel pitch detector with the 60 kVp X-ray tube and 5 keV noise level. No significant degradation in performance was observed for X-ray tube energies of 20 - 60 keV. The paper discusses the application of the CdTe Timepix detector to produce a good quality image of X-ray tomography imaging.

  3. Design, Implementation and Applications of 3d Web-Services in DB4GEO

    NASA Astrophysics Data System (ADS)

    Breunig, M.; Kuper, P. V.; Dittrich, A.; Wild, P.; Butwilowski, E.; Al-Doori, M.

    2013-09-01

    The object-oriented database architecture DB4GeO was originally designed to support sub-surface applications in the geo-sciences. This is reflected in DB4GeO's geometric data model as well as in its import and export functions. Initially, these functions were designed for communication with 3D geological modeling and visualization tools such as GOCAD or MeshLab. However, it soon became clear that DB4GeO was suitable for a much wider range of applications. Therefore it is natural to move away from a standalone solution and to open the access to DB4GeO data by standardized OGC web-services. Though REST and OGC services seem incompatible at first sight, the implementation in DB4GeO shows that OGC-based implementation of web-services may use parts of the DB4GeO-REST implementation. Starting with initial solutions in the history of DB4GeO, this paper will introduce the design, adaptation (i.e. model transformation), and first steps in the implementation of OGC Web Feature (WFS) and Web Processing Services (WPS), as new interfaces to DB4GeO data and operations. Among its capabilities, DB4GeO can provide data in different data formats like GML, GOCAD, or DB3D XML through a WFS, as well as its ability to run operations like a 3D-to-2D service, or mesh-simplification (Progressive Meshes) through a WPS. We then demonstrate, an Android-based mobile 3D augmented reality viewer for DB4GeO that uses the Web Feature Service to visualize 3D geo-database query results. Finally, we explore future research work considering DB4GeO in the framework of the research group "Computer-Aided Collaborative Subway Track Planning in Multi-Scale 3D City and Building Models".

  4. GPU color space conversion

    NASA Astrophysics Data System (ADS)

    Chase, Patrick; Vondran, Gary

    2011-01-01

    Tetrahedral interpolation is commonly used to implement continuous color space conversions from sparse 3D and 4D lookup tables. We investigate the implementation and optimization of tetrahedral interpolation algorithms for GPUs, and compare to the best known CPU implementations as well as to a well known GPU-based trilinear implementation. We show that a 500 NVIDIA GTX-580 GPU is 3x faster than a 1000 Intel Core i7 980X CPU for 3D interpolation, and 9x faster for 4D interpolation. Performance-relevant GPU attributes are explored including thread scheduling, local memory characteristics, global memory hierarchy, and cache behaviors. We consider existing tetrahedral interpolation algorithms and tune based on the structure and branching capabilities of current GPUs. Global memory performance is improved by reordering and expanding the lookup table to ensure optimal access behaviors. Per multiprocessor local memory is exploited to implement optimally coalesced global memory accesses, and local memory addressing is optimized to minimize bank conflicts. We explore the impacts of lookup table density upon computation and memory access costs. Also presented are CPU-based 3D and 4D interpolators, using SSE vector operations that are faster than any previously published solution.

  5. Web-based interactive 3D visualization as a tool for improved anatomy learning.

    PubMed

    Petersson, Helge; Sinkvist, David; Wang, Chunliang; Smedby, Orjan

    2009-01-01

    Despite a long tradition, conventional anatomy education based on dissection is declining. This study tested a new virtual reality (VR) technique for anatomy learning based on virtual contrast injection. The aim was to assess whether students value this new three-dimensional (3D) visualization method as a learning tool and what value they gain from its use in reaching their anatomical learning objectives. Several 3D vascular VR models were created using an interactive segmentation tool based on the "virtual contrast injection" method. This method allows users, with relative ease, to convert computer tomography or magnetic resonance images into vivid 3D VR movies using the OsiriX software equipped with the CMIV CTA plug-in. Once created using the segmentation tool, the image series were exported in Quick Time Virtual Reality (QTVR) format and integrated within a web framework of the Educational Virtual Anatomy (EVA) program. A total of nine QTVR movies were produced encompassing most of the major arteries of the body. These movies were supplemented with associated information, color keys, and notes. The results indicate that, in general, students' attitudes towards the EVA-program were positive when compared with anatomy textbooks, but results were not the same with dissections. Additionally, knowledge tests suggest a potentially beneficial effect on learning.

  6. Human Visual Performance and Flat Panel Display Image Quality

    DTIC Science & Technology

    1980-07-01

    the research required to relate human operator performance to the geome- tric properties of these designs has characteristically lag- - 68 - tte ...see: A summary of basic principles. In Committee on Undersea Warfare, National Research Council, A Summary Report on Human Factors in Undersea ...Office of the Deputy Under Secretary of Defense OUSDRE (E&LS) The Pentagon, Room 3D129 Washington, D. C. 20301 Director, Undersea Technology Code 220

  7. Real-time classification of vehicles by type within infrared imagery

    NASA Astrophysics Data System (ADS)

    Kundegorski, Mikolaj E.; Akçay, Samet; Payen de La Garanderie, Grégoire; Breckon, Toby P.

    2016-10-01

    Real-time classification of vehicles into sub-category types poses a significant challenge within infra-red imagery due to the high levels of intra-class variation in thermal vehicle signatures caused by aspects of design, current operating duration and ambient thermal conditions. Despite these challenges, infra-red sensing offers significant generalized target object detection advantages in terms of all-weather operation and invariance to visual camouflage techniques. This work investigates the accuracy of a number of real-time object classification approaches for this task within the wider context of an existing initial object detection and tracking framework. Specifically we evaluate the use of traditional feature-driven bag of visual words and histogram of oriented gradient classification approaches against modern convolutional neural network architectures. Furthermore, we use classical photogrammetry, within the context of current target detection and classification techniques, as a means of approximating 3D target position within the scene based on this vehicle type classification. Based on photogrammetric estimation of target position, we then illustrate the use of regular Kalman filter based tracking operating on actual 3D vehicle trajectories. Results are presented using a conventional thermal-band infra-red (IR) sensor arrangement where targets are tracked over a range of evaluation scenarios.

  8. Study of the X-Ray Diagnosis of Unstable Pelvic Fracture Displacements in Three-Dimensional Space and its Application in Closed Reduction.

    PubMed

    Shi, Chengdi; Cai, Leyi; Hu, Wei; Sun, Junying

    2017-09-19

    ABSTRACTS Objective: To study the method of X-ray diagnosis of unstable pelvic fractures displaced in three-dimensional (3D) space and its clinical application in closed reduction. Five models of hemipelvic displacement were made in an adult pelvic specimen. Anteroposterior radiographs of the pelvis were analyzed in PACS. The method of X-ray diagnosis was applied in closed reductions. From February 2012 to June 2016, 23 patients (15 men, 8 women; mean age, 43.4 years) with unstable pelvic fractures were included. All patients were treated by closed reduction and percutaneous cannulate screw fixation of the pelvic ring. According to Tile's classification, the patients were classified into type B1 in 7 cases, B2 in 3, B3 in 3, C1 in 5, C2 in 3, and C3 in 2. The operation time and intraoperative blood loss were recorded. Postoperative images were evaluated by Matta radiographic standards. Five models of displacement were made successfully. The X-ray features of the models were analyzed. For clinical patients, the average operation time was 44.8 min (range, 20-90 min) and the average intraoperative blood loss was 35.7 (range, 20-100) mL. According to the Matta standards, 7 cases were excellent, 12 cases were good, and 4 were fair. The displacements in 3D space of unstable pelvic fractures can be diagnosed rapidly by X-ray analysis to guide closed reduction, with a satisfactory clinical outcome.

  9. A three-dimensional radiation image display on a real space image created via photogrammetry

    NASA Astrophysics Data System (ADS)

    Sato, Y.; Ozawa, S.; Tanifuji, Y.; Torii, T.

    2018-03-01

    The Fukushima Daiichi Nuclear Power Station (FDNPS), operated by Tokyo Electric Power Company Holdings, Inc., went into meltdown after the occurrence of a large tsunami caused by the Great East Japan Earthquake of March 11, 2011. The radiation distribution measurements inside the FDNPS buildings are indispensable to execute decommissioning tasks in the reactor buildings. We have developed a three-dimensional (3D) image reconstruction method for radioactive substances using a compact Compton camera. Moreover, we succeeded in visually recognizing the position of radioactive substances in real space by the integration of 3D radiation images and the 3D photo-model created using photogrammetry.

  10. High Power SiGe X-Band (8-10 GHz) Heterojunction Bipolar Transistors and Amplifiers

    NASA Technical Reports Server (NTRS)

    Ma, Zhenqiang; Jiang, Ningyue; Ponchak, George E.; Alterovitz, Samuel A.

    2005-01-01

    Limited by increased parasitics and thermal effects as the device size becomes large, current commercial SiGe power HBTs are difficult to operate at X-band (8-12 GHz) with adequate power added efficiencies at high power levels. We found that, by changing the heterostructure and doping profile of SiGe HBTs, their power gain can be significantly improved without resorting to substantial lateral scaling. Furthermore, employing a common-base configuration with proper doping profile instead of a common-emitter configuration improves the power gain characteristics of SiGe HBTs, which thus permits these devices to be efficiently operated at X-band. In this paper, we report the results of SiGe power HBTs and MMIC power amplifiers operating at 8-10 GHz. At 10 GHz, 22.5 dBm (178 mW) RF output power with concurrent gain of 7.32 dB is measured at the peak power-added efficiency of 20.0% and the maximum RF output power of 24.0 dBm (250 mW) is achieved from a 20 emitter finger SiGe power HBT. Demonstration of single-stage X-band medium-power linear MMIC power amplifier is also realized at 8 GHz. Employing a 10-emitter finger SiGe HBT and on-chip input and output matching passive components, a linear gain of 9.7 dB, a maximum output power of 23.4 dBm and peak power added efficiency of 16% is achieved from the power amplifier. The MMIC exhibits very low distortion with third order intermodulation (IM) suppression C/I of -13 dBc at output power of 21.2 dBm and over 20dBm third order output intercept point (OIP3).

  11. Real-time three-dimensional imaging of epidermal splitting and removal by high-definition optical coherence tomography.

    PubMed

    Boone, Marc; Draye, Jean Pierre; Verween, Gunther; Pirnay, Jean-Paul; Verbeken, Gilbert; De Vos, Daniel; Rose, Thomas; Jennes, Serge; Jemec, Gregor B E; Del Marmol, Véronique

    2014-10-01

    While real-time 3-D evaluation of human skin constructs is needed, only 2-D non-invasive imaging techniques are available. The aim of this paper is to evaluate the potential of high-definition optical coherence tomography (HD-OCT) for real-time 3-D assessment of the epidermal splitting and decellularization. Human skin samples were incubated with four different agents: Dispase II, NaCl 1 M, sodium dodecyl sulphate (SDS) and Triton X-100. Epidermal splitting, dermo-epidermal junction, acellularity and 3-D architecture of dermal matrices were evaluated by High-definition optical coherence tomography before and after incubation. Real-time 3-D HD-OCT assessment was compared with 2-D en face assessment by reflectance confocal microscopy (RCM). (Immuno) histopathology was used as control. HD-OCT imaging allowed real-time 3-D visualization of the impact of selected agents on epidermal splitting, dermo-epidermal junction, dermal architecture, vascular spaces and cellularity. RCM has a better resolution (1 μm) than HD-OCT (3 μm), permitting differentiation of different collagen fibres, but HD-OCT imaging has deeper penetration (570 μm) than RCM imaging (200 μm). Dispase II and NaCl treatments were found to be equally efficient in the removal of the epidermis from human split-thickness skin allografts. However, a different epidermal splitting level at the dermo-epidermal junction could be observed and confirmed by immunolabelling of collagen type IV and type VII. Epidermal splitting occurred at the level of the lamina densa with dispase II and above the lamina densa (in the lamina lucida) with NaCl. The 3-D architecture of dermal papillae and dermis was more affected by Dispase II on HD-OCT which corresponded with histopathologic (orcein staining) fragmentation of elastic fibres. With SDS treatment, the epidermal removal was incomplete as remnants of the epidermal basal cell layer remained attached to the basement membrane on the dermis. With Triton X-100 treatment, the epidermis was not removed. In conclusion, HD-OCT imaging permits real-time 3-D visualization of the impact of selected agents on human skin allografts. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. Visual perceptual load reduces auditory detection in typically developing individuals but not in individuals with autism spectrum disorders.

    PubMed

    Tillmann, Julian; Swettenham, John

    2017-02-01

    Previous studies examining selective attention in individuals with autism spectrum disorder (ASD) have yielded conflicting results, some suggesting superior focused attention (e.g., on visual search tasks), others demonstrating greater distractibility. This pattern could be accounted for by the proposal (derived by applying the Load theory of attention, e.g., Lavie, 2005) that ASD is characterized by an increased perceptual capacity (Remington, Swettenham, Campbell, & Coleman, 2009). Recent studies in the visual domain support this proposal. Here we hypothesize that ASD involves an enhanced perceptual capacity that also operates across sensory modalities, and test this prediction, for the first time using a signal detection paradigm. Seventeen neurotypical (NT) and 15 ASD adolescents performed a visual search task under varying levels of visual perceptual load while simultaneously detecting presence/absence of an auditory tone embedded in noise. Detection sensitivity (d') for the auditory stimulus was similarly high for both groups in the low visual perceptual load condition (e.g., 2 items: p = .391, d = 0.31, 95% confidence interval [CI] [-0.39, 1.00]). However, at a higher level of visual load, auditory d' reduced for the NT group but not the ASD group, leading to a group difference (p = .002, d = 1.2, 95% CI [0.44, 1.96]). As predicted, when visual perceptual load was highest, both groups then showed a similarly low auditory d' (p = .9, d = 0.05, 95% CI [-0.65, 0.74]). These findings demonstrate that increased perceptual capacity in ASD operates across modalities. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Developing Mobile- and BIM-Based Integrated Visual Facility Maintenance Management System

    PubMed Central

    Su, Yu-Chih

    2013-01-01

    Facility maintenance management (FMM) has become an important topic for research on the operation phase of the construction life cycle. Managing FMM effectively is extremely difficult owing to various factors and environments. One of the difficulties is the performance of 2D graphics when depicting maintenance service. Building information modeling (BIM) uses precise geometry and relevant data to support the maintenance service of facilities depicted in 3D object-oriented CAD. This paper proposes a new and practical methodology with application to FMM using BIM technology. Using BIM technology, this study proposes a BIM-based facility maintenance management (BIMFMM) system for maintenance staff in the operation and maintenance phase. The BIMFMM system is then applied in selected case study of a commercial building project in Taiwan to verify the proposed methodology and demonstrate its effectiveness in FMM practice. Using the BIMFMM system, maintenance staff can access and review 3D BIM models for updating related maintenance records in a digital format. Moreover, this study presents a generic system architecture and its implementation. The combined results demonstrate that a BIMFMM-like system can be an effective visual FMM tool. PMID:24227995

  14. An Instructional Method for the AutoCAD Modeling Environment.

    ERIC Educational Resources Information Center

    Mohler, James L.

    1997-01-01

    Presents a command organizer for AutoCAD to aid new uses in operating within the 3-D modeling environment. Addresses analyzing the problem, visualization skills, nonlinear tools, a static view of a dynamic model, the AutoCAD organizer, environment attributes, and control of the environment. Contains 11 references. (JRH)

  15. Multimodal-3D imaging based on μMRI and μCT techniques bridges the gap with histology in visualization of the bone regeneration process.

    PubMed

    Sinibaldi, R; Conti, A; Sinjari, B; Spadone, S; Pecci, R; Palombo, M; Komlev, V S; Ortore, M G; Tromba, G; Capuani, S; Guidotti, R; De Luca, F; Caputi, S; Traini, T; Della Penna, S

    2018-03-01

    Bone repair/regeneration is usually investigated through X-ray computed microtomography (μCT) supported by histology of extracted samples, to analyse biomaterial structure and new bone formation processes. Magnetic resonance imaging (μMRI) shows a richer tissue contrast than μCT, despite at lower resolution, and could be combined with μCT in the perspective of conducting non-destructive 3D investigations of bone. A pipeline designed to combine μMRI and μCT images of bone samples is here described and applied on samples of extracted human jawbone core following bone graft. We optimized the coregistration procedure between μCT and μMRI images to avoid bias due to the different resolutions and contrasts. Furthermore, we used an Adaptive Multivariate Clustering, grouping homologous voxels in the coregistered images, to visualize different tissue types within a fused 3D metastructure. The tissue grouping matched the 2D histology applied only on 1 slice, thus extending the histology labelling in 3D. Specifically, in all samples, we could separate and map 2 types of regenerated bone, calcified tissue, soft tissues, and/or fat and marrow space. Remarkably, μMRI and μCT alone were not able to separate the 2 types of regenerated bone. Finally, we computed volumes of each tissue in the 3D metastructures, which might be exploited by quantitative simulation. The 3D metastructure obtained through our pipeline represents a first step to bridge the gap between the quality of information obtained from 2D optical microscopy and the 3D mapping of the bone tissue heterogeneity and could allow researchers and clinicians to non-destructively characterize and follow-up bone regeneration. Copyright © 2017 John Wiley & Sons, Ltd.

  16. Visualization of anthropometric measures of workers in computer 3D modeling of work place.

    PubMed

    Mijović, B; Ujević, D; Baksa, S

    2001-12-01

    In this work, 3D visualization of a work place by means of a computer-made 3D-machine model and computer animation of a worker have been performed. By visualization of 3D characters in inverse kinematic and dynamic relation with the operating part of a machine, the biomechanic characteristics of worker's body have been determined. The dimensions of a machine have been determined by an inspection of technical documentation as well as by direct measurements and recordings of the machine by camera. On the basis of measured body height of workers all relevant anthropometric measures have been determined by a computer program developed by the authors. By knowing the anthropometric measures, the vision fields and the scope zones while forming work places, exact postures of workers while performing technological procedures were determined. The minimal and maximal rotation angles and the translation of upper and lower arm which are basis for the analysis of worker burdening were analyzed. The dimensions of the seized space of a body are obtained by computer anthropometric analysis of movement, e.g. range of arms, position of legs, head, back. The influence of forming of a work place on correct postures of workers during work has been reconsidered and thus the consumption of energy and fatigue can be reduced to a minimum.

  17. Volumetric characterization of human patellar cartilage matrix on phase contrast x-ray computed tomography

    NASA Astrophysics Data System (ADS)

    Abidin, Anas Z.; Nagarajan, Mahesh B.; Checefsky, Walter A.; Coan, Paola; Diemoz, Paul C.; Hobbs, Susan K.; Huber, Markus B.; Wismüller, Axel

    2015-03-01

    Phase contrast X-ray computed tomography (PCI-CT) has recently emerged as a novel imaging technique that allows visualization of cartilage soft tissue, subsequent examination of chondrocyte patterns, and their correlation to osteoarthritis. Previous studies have shown that 2D texture features are effective at distinguishing between healthy and osteoarthritic regions of interest annotated in the radial zone of cartilage matrix on PCI-CT images. In this study, we further extend the texture analysis to 3D and investigate the ability of volumetric texture features at characterizing chondrocyte patterns in the cartilage matrix for purposes of classification. Here, we extracted volumetric texture features derived from Minkowski Functionals and gray-level co-occurrence matrices (GLCM) from 496 volumes of interest (VOI) annotated on PCI-CT images of human patellar cartilage specimens. The extracted features were then used in a machine-learning task involving support vector regression to classify ROIs as healthy or osteoarthritic. Classification performance was evaluated using the area under the receiver operating characteristic (ROC) curve (AUC). The best classification performance was observed with GLCM features correlation (AUC = 0.83 +/- 0.06) and homogeneity (AUC = 0.82 +/- 0.07), which significantly outperformed all Minkowski Functionals (p < 0.05). These results suggest that such quantitative analysis of chondrocyte patterns in human patellar cartilage matrix involving GLCM-derived statistical features can distinguish between healthy and osteoarthritic tissue with high accuracy.

  18. Influence of gas conditions on electron temperature inside a pinch column of plasma-focus discharge

    NASA Astrophysics Data System (ADS)

    Zaloga, D. R.; Sadowski, M. J.; Skladnik-Sadowska, E.; Paduch, M.; Zielinska, E.; Tomaszewski, K.

    2018-01-01

    The paper reports on soft x-ray emission from high-current discharges in PF-1000U facility operated at 170 kJ. The discharges at static conditions were performed with pure deuterium (D2) and a mixture of D2 and neon (Ne). In shots with the gas-puffing 1 cm3 of D2 or a (D2+Ne) mixture was injected 2 ms before the discharge initiation. Time-integrated x-ray images from a Be-filtered pinhole camera showed that the pinch microstructure depends strongly on gas conditions. In shots with the D2-, (D2+Ne)- or He-puffing distinct “filaments” and “hot-spots” were observed. Time-resolved x-ray pulses were recorded with 4 filtered PIN-diodes which recorded signals from 2 regions of 3 cm in diameter (at z = 3 cm and 6 cm from the anode). From a ratio of x-ray pulses, measured behind different filters, it was estimated that at the static D2-filling electron temperatures (Te ) were from 90 eV to 200 eV. At the D2-filling and -puffing additional x-ray spikes were emitted from “hot-spots” with Te twice higher. In shots at the (D2+10%Ne)-filling Te was 4 keV. In shots with the (D2+Ne)-mixture puffing intense “hot-spots” were formed, and Te reached 2.2-7.5 keV. At the same conditions “filaments” were reproducible macroscopically, but “hot-spots” were irreproducible.

  19. Immersive Visualization of the Solid Earth

    NASA Astrophysics Data System (ADS)

    Kreylos, O.; Kellogg, L. H.

    2017-12-01

    Immersive visualization using virtual reality (VR) display technology offers unique benefits for the visual analysis of complex three-dimensional data such as tomographic images of the mantle and higher-dimensional data such as computational geodynamics models of mantle convection or even planetary dynamos. Unlike "traditional" visualization, which has to project 3D scalar data or vectors onto a 2D screen for display, VR can display 3D data in a pseudo-holographic (head-tracked stereoscopic) form, and does therefore not suffer the distortions of relative positions, sizes, distances, and angles that are inherent in 2D projection and interfere with interpretation. As a result, researchers can apply their spatial reasoning skills to 3D data in the same way they can to real objects or environments, as well as to complex objects like vector fields. 3D Visualizer is an application to visualize 3D volumetric data, such as results from mantle convection simulations or seismic tomography reconstructions, using VR display technology and a strong focus on interactive exploration. Unlike other visualization software, 3D Visualizer does not present static visualizations, such as a set of cross-sections at pre-selected positions and orientations, but instead lets users ask questions of their data, for example by dragging a cross-section through the data's domain with their hands and seeing data mapped onto that cross-section in real time, or by touching a point inside the data domain, and immediately seeing an isosurface connecting all points having the same data value as the touched point. Combined with tools allowing 3D measurements of positions, distances, and angles, and with annotation tools that allow free-hand sketching directly in 3D data space, the outcome of using 3D Visualizer is not primarily a set of pictures, but derived data to be used for subsequent analysis. 3D Visualizer works best in virtual reality, either in high-end facility-scale environments such as CAVEs, or using commodity low-cost virtual reality headsets such as HTC's Vive. The recent emergence of high-quality commodity VR means that researchers can buy a complete VR system off the shelf, install it and the 3D Visualizer software themselves, and start using it for data analysis immediately.

  20. a New Idea of Bim System for Visualization, Web Sharing and Using Huge Complex 3d Models for Facility Management.

    NASA Astrophysics Data System (ADS)

    Fassi, F.; Achille, C.; Mandelli, A.; Rechichi, F.; Parri, S.

    2015-02-01

    The work is the final part of a multi-year research project on the Milan Cathedral, which focused on the complete survey and threedimensional modeling of the Great Spire (Fassi et al., 2011) and the two altars in the transept. The main purpose of the job was to prepare support data for the maintenance operations involving the cathedral since 2009 and still in progress. The research job had begun addressing our efforts to identify which methods would allow an expeditious but comprehensive measure of complex architectural structure as a whole. (Achille et al., 2012) The following research works were focused mainly to find an efficient method to visualize, use and share the realized 3D model.

  1. Five-dimensional ultrasound system for soft tissue visualization.

    PubMed

    Deshmukh, Nishikant P; Caban, Jesus J; Taylor, Russell H; Hager, Gregory D; Boctor, Emad M

    2015-12-01

    A five-dimensional ultrasound (US) system is proposed as a real-time pipeline involving fusion of 3D B-mode data with the 3D ultrasound elastography (USE) data as well as visualization of these fused data and a real-time update capability over time for each consecutive scan. 3D B-mode data assist in visualizing the anatomy of the target organ, and 3D elastography data adds strain information. We investigate the feasibility of such a system and show that an end-to-end real-time system, from acquisition to visualization, can be developed. We present a system that consists of (a) a real-time 3D elastography algorithm based on a normalized cross-correlation (NCC) computation on a GPU; (b) real-time 3D B-mode acquisition and network transfer; (c) scan conversion of 3D elastography and B-mode volumes (if acquired by 4D wobbler probe); and (d) visualization software that fuses, visualizes, and updates 3D B-mode and 3D elastography data in real time. We achieved a speed improvement of 4.45-fold for the threaded version of the NCC-based 3D USE versus the non-threaded version. The maximum speed was 79 volumes/s for 3D scan conversion. In a phantom, we validated the dimensions of a 2.2-cm-diameter sphere scan-converted to B-mode volume. Also, we validated the 5D US system visualization transfer function and detected 1- and 2-cm spherical objects (phantom lesion). Finally, we applied the system to a phantom consisting of three lesions to delineate the lesions from the surrounding background regions of the phantom. A 5D US system is achievable with real-time performance. We can distinguish between hard and soft areas in a phantom using the transfer functions.

  2. [Effect of different sludge retention time (SRT) on municipal sewage sludge bioleaching continuous plug flow reaction system].

    PubMed

    Liu, Fen-Wu; Zhou, Li-Xiang; Zhou, Jun; Jiang, Feng; Wang, Dian-Zhan

    2012-01-01

    A plug-flow bio-reactor of 700 L working volume for sludge bioleaching was used in this study. The reactor was divided into six sections along the direction of the sludge movement. Fourteen days of continuous operation of sludge bioleaching with different sludge retention time (SRT) under the condition of 1.2 m3 x h(-1) aeration amount and 4 g x L(-1) of microbial nutritional substance was conducted. During sludge bioleaching, the dynamic changes of pH, DO, dewaterability (specific resistance to filtration, SRF) of sewage sludge in different sections were investigated in the present study. The results showed that sludge pH were maintained at 5.00, 3.00, 2.90, 2.70, 2.60 and 2.40 from section 1 to section 6 and the SRF of sludge was drastically decreased from initial 0.64 x 10(13) m x kg(-1) to the final 0.33 x 10(13) m x kg(-1) when bioleaching system reached stable at hour 72 with SRT 2.5d. In addition, the sludge pH were maintained at 5.10, 4.10, 3.20, 2.90, 2.70 and 2.60, the DO value were 0.43, 1.47, 3.29, 4.76, 5.75 and 5.88 mg x L(-1) from section 1 to section 6, and the SRF of sludge was drastically decreased from initial 0.56 x 10(13) to the final 0.20 x 10(13) m x kg(-1) when bioleaching system reached stable at hour 120 with SRT 2 d. The pH value was increased to 3.00 at section 6 at hour 48 h with SRT 1.25 d. The bioleaching system imbalanced in this operation conditions because of the utilization efficiency of microbial nutritional substance by Acidibacillus spp. was decreased. The longer sludge retention time, the easier bioleaching system reached stable. 2 d could be used as the optimum sludge retention time in engineering application. The bioleached sludge was collected and dewatered by plate-and-frame filter press to the moisture content of dewatered sludge cake under 60%. This study would provide the necessary data to the engineering application on municipal sewage sludge bioleaching.

  3. A study of the effects of degraded imagery on tactical 3D model generation using structure-from-motion

    NASA Astrophysics Data System (ADS)

    Bolick, Leslie; Harguess, Josh

    2016-05-01

    An emerging technology in the realm of airborne intelligence, surveillance, and reconnaissance (ISR) systems is structure-from-motion (SfM), which enables the creation of three-dimensional (3D) point clouds and 3D models from two-dimensional (2D) imagery. There are several existing tools, such as VisualSFM and open source project OpenSfM, to assist in this process, however, it is well-known that pristine imagery is usually required to create meaningful 3D data from the imagery. In military applications, such as the use of unmanned aerial vehicles (UAV) for surveillance operations, imagery is rarely pristine. Therefore, we present an analysis of structure-from-motion packages on imagery that has been degraded in a controlled manner.

  4. Human visual performance model for crewstation design

    NASA Technical Reports Server (NTRS)

    Larimer, James; Prevost, Michael; Arditi, Aries; Azueta, Steven; Bergen, James; Lubin, Jeffrey

    1991-01-01

    An account is given of a Visibility Modeling Tool (VMT) which furnishes a crew-station designer with the means to assess configurational tradeoffs, with a view to the impact of various options on the unambiguous access of information to the pilot. The interactive interface of the VMT allows the manipulation of cockpit geometry, ambient lighting, pilot ergonomics, and the displayed symbology. Performance data can be displayed in the form of 3D contours into the crewstation graphic model, thereby yielding an indication of the operator's visual capabilities.

  5. Noninvasive CT to Iso-C3D registration for improved intraoperative visualization in computer assisted orthopedic surgery

    NASA Astrophysics Data System (ADS)

    Rudolph, Tobias; Ebert, Lars; Kowal, Jens

    2006-03-01

    Supporting surgeons in performing minimally invasive surgeries can be considered as one of the major goals of computer assisted surgery. Excellent intraoperative visualization is a prerequisite to achieve this aim. The Siremobil Iso-C 3D has become a widely used imaging device, which, in combination with a navigation system, enables the surgeon to directly navigate within the acquired 3D image volume without any extra registration steps. However, the image quality is rather low compared to a CT scan and the volume size (approx. 12 cm 3) limits its application. A regularly used alternative in computer assisted orthopedic surgery is to use of a preoperatively acquired CT scan to visualize the operating field. But, the additional registration step, necessary in order to use CT stacks for navigation is quite invasive. Therefore the objective of this work is to develop a noninvasive registration technique. In this article a solution is being proposed that registers a preoperatively acquired CT scan to the intraoperatively acquired Iso-C 3D image volume, thereby registering the CT to the tracked anatomy. The procedure aligns both image volumes by maximizing the mutual information, an algorithm that has already been applied to similar registration problems and demonstrated good results. Furthermore the accuracy of such a registration method was investigated in a clinical setup, integrating a navigated Iso-C 3D in combination with an tracking system. Initial tests based on cadaveric animal bone resulted in an accuracy ranging from 0.63mm to 1.55mm mean error.

  6. Orthogonal Rings, Fiducial Markers, and Overlay Accuracy When Image Fusion is Used for EVAR Guidance.

    PubMed

    Koutouzi, G; Sandström, C; Roos, H; Henrikson, O; Leonhardt, H; Falkenberg, M

    2016-11-01

    Evaluation of orthogonal rings, fiducial markers, and overlay accuracy when image fusion is used for endovascular aortic repair (EVAR). This was a prospective single centre study. In 19 patients undergoing standard EVAR, 3D image fusion was used for intra-operative guidance. Renal arteries and targeted stent graft positions were marked with rings orthogonal to the respective centre lines from pre-operative computed tomography (CT). Radiopaque reference objects attached to the back of the patient were used as fiducial markers to detect patient movement intra-operatively. Automatic 3D-3D registration of the pre-operative CT with an intra-operative cone beam computed tomography (CBCT) as well as 3D-3D registration after manual alignment of nearby vertebrae were evaluated. Registration was defined as being sufficient for EVAR guidance if the deviation of the origin of the lower renal artery was less than 3 mm. For final overlay registration, the renal arteries were manually aligned using aortic calcification and vessel outlines. The accuracy of the overlay before stent graft deployment was evaluated using digital subtraction angiography (DSA) as direct comparison. Fiducial markers helped in detecting misalignment caused by patient movement during the procedure. Use of automatic intensity based registration alone was insufficient for EVAR guidance. Manual registration based on vertebrae L1-L2 was sufficient in 7/19 patients (37%). Using the final adjusted registration as overlay, the median alignment error of the lower renal artery marking at pre-deployment DSA was 2 mm (0-5) sideways and 2 mm (0-9) longitudinally, mostly in a caudal direction. 3D image fusion can facilitate intra-operative guidance during EVAR. Orthogonal rings and fiducial markers are useful for visualization and overlay correction. However, the accuracy of the overlaid 3D image is not always ideal and further technical development is needed. Copyright © 2016 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

  7. X-ray micro-CT and neutron CT as complementary imaging tools for non-destructive 3D imaging of rare silicified fossil plants

    NASA Astrophysics Data System (ADS)

    Karch, J.; Dudák, J.; Žemlička, J.; Vavřík, D.; Kumpová, I.; Kvaček, J.; Heřmanová, Z.; Šoltés, J.; Viererbl, L.; Morgano, M.; Kaestner, A.; Trtík, P.

    2017-12-01

    Computed tomography provides 3D information of inner structures of investigated objects. The obtained information is, however, strongly dependent on the used radiation type. It is known that as X-rays interact with electron cloud and neutrons with atomic nucleus, the obtained data often provide different contrast of sample structures. In this work we present a set of comparative radiographic and CT measurements of rare fossil plant samples using X-rays and thermal neutrons. The X-ray measurements were performed using large area photon counting detectors Timepix at IEAP CTU in Prague and Perkin Elmer flat-panel detector at Center of Excellence Telč. The neutron CT measurement was carried out at Paul Scherrer Institute using BOA beam-line. Furthermore, neutron radiography of fossil samples, provided by National Museum, were performed using a large-area Timepix detector with a neutron-sensitive converting 6LiF layer at Research Centre Rez, Czech Republic. The obtained results show different capabilities of both imaging approaches. While X-ray micro-CT provides very high resolution and enables visualization of fine cracks or small cavities in the samples neutron imaging provides high contrast of morphological structures of fossil plant samples, where X-ray imaging provides insufficient contrast.

  8. Web-based hydrodynamics computing

    NASA Astrophysics Data System (ADS)

    Shimoide, Alan; Lin, Luping; Hong, Tracie-Lynne; Yoon, Ilmi; Aragon, Sergio R.

    2005-01-01

    Proteins are long chains of amino acids that have a definite 3-d conformation and the shape of each protein is vital to its function. Since proteins are normally in solution, hydrodynamics (describes the movement of solvent around a protein as a function of shape and size of the molecule) can be used to probe the size and shape of proteins compared to those derived from X-ray crystallography. The computation chain needed for these hydrodynamics calculations consists of several separate programs by different authors on various platforms and often requires 3D visualizations of intermediate results. Due to the complexity, tools developed by a particular research group are not readily available for use by other groups, nor even by the non-experts within the same research group. To alleviate this situation, and to foment the easy and wide distribution of computational tools worldwide, we developed a web based interactive computational environment (WICE) including interactive 3D visualization that can be used with any web browser. Java based technologies were used to provide a platform neutral, user-friendly solution. Java Server Pages (JSP), Java Servlets, Java Beans, JOGL (Java bindings for OpenGL), and Java Web Start were used to create a solution that simplifies the computing chain for the user allowing the user to focus on their scientific research. WICE hides complexity from the user and provides robust and sophisticated visualization through a web browser.

  9. Web-based hydrodynamics computing

    NASA Astrophysics Data System (ADS)

    Shimoide, Alan; Lin, Luping; Hong, Tracie-Lynne; Yoon, Ilmi; Aragon, Sergio R.

    2004-12-01

    Proteins are long chains of amino acids that have a definite 3-d conformation and the shape of each protein is vital to its function. Since proteins are normally in solution, hydrodynamics (describes the movement of solvent around a protein as a function of shape and size of the molecule) can be used to probe the size and shape of proteins compared to those derived from X-ray crystallography. The computation chain needed for these hydrodynamics calculations consists of several separate programs by different authors on various platforms and often requires 3D visualizations of intermediate results. Due to the complexity, tools developed by a particular research group are not readily available for use by other groups, nor even by the non-experts within the same research group. To alleviate this situation, and to foment the easy and wide distribution of computational tools worldwide, we developed a web based interactive computational environment (WICE) including interactive 3D visualization that can be used with any web browser. Java based technologies were used to provide a platform neutral, user-friendly solution. Java Server Pages (JSP), Java Servlets, Java Beans, JOGL (Java bindings for OpenGL), and Java Web Start were used to create a solution that simplifies the computing chain for the user allowing the user to focus on their scientific research. WICE hides complexity from the user and provides robust and sophisticated visualization through a web browser.

  10. Visual and refractive outcomes of LASIK with the SCHWIND ESIRIS and WaveLight ALLEGRETTO WAVE Eye-q excimer lasers: a prospective, contralateral study.

    PubMed

    Mearza, Ali A; Muhtaseb, Mohammed; Aslanides, Ioannis M

    2008-11-01

    To compare the safety, efficacy, and predictability of LASIK with the SCHWIND ESIRIS and WaveLight ALLEGRETTO WAVE Eye-Q excimer laser platforms. This prospective study comprised 44 eyes of 22 consecutive patients who were treated with LASIK using the Moria M2 microkeratome. One eye was treated with the SCHWIND ESIRIS laser and the fellow eye treated with the WaveLight ALLEGRETTO WAVE Eye-Q laser. All eyes operated with the SCHWIND ESIRIS were treated with standard aspheric ablation, whereas the eyes operated with the WaveLight ALLEGRETTO WAVE Eye-Q received treatment with three different ablation types according to the common practice at our clinic. Outcome measures were uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, and proximity to target refraction at 6-month follow-up. At 6 months postoperative, mean decimal UCVA was 0.96+/-0.22 (range: 0.3 to 1.2) for ESIRIS eyes and 0.98+/-0.17 (range: 0.6 to 1.2) for ALLEGRETTO eyes (P=.57). Mean postoperative spherical equivalent refraction was -0.02+/-0.28 diopters (D) (range: -0.75 to +0.75 D) for ESIRIS eyes and 0.11+/-0.91 D (range: -1.00 to +3.88 D) for ALLEGRETTO eyes (P=.49). Of the ESIRIS eyes, 20/22 (91%) were within +/-1.00 D of target refraction and 20/22 (91%) were within +/-0.50 D of target refraction. Of the ALLEGRETTO eyes, 20/22 (91%) and 19/22 (86%) were within +/-1.00 D and +/-0.50 D, respectively, of target refraction. No patient lost > or =2 lines of BSCVA in either group. No differences were seen in safety and efficacy outcome parameters between the SCHWIND ESIRIS and WaveLight ALLEGRETTO WAVE Eye-Q excimer lasers when used according to a previously established treatment algorithm at our clinic in the treatment of refractive error.

  11. Three-dimensional high-speed optical coherence tomography imaging of lamina cribrosa in glaucoma.

    PubMed

    Inoue, Ryo; Hangai, Masanori; Kotera, Yuriko; Nakanishi, Hideo; Mori, Satoshi; Morishita, Shiho; Yoshimura, Nagahisa

    2009-02-01

    To evaluate the appearance of the optic nerve head and lamina cribrosa in patients with glaucoma using spectral/Fourier-domain optical coherence tomography (SD-OCT) and to test for a correlation between lamina cribrosa thickness measured on SD-OCT images and visual field loss. Observational case series. We evaluated 52 eyes of 30 patients with glaucoma or ocular hypertension. The high-speed SD-OCT equipment used was a prototype system developed for 3-dimensional (3D) imaging. It had a sensitivity of 98 decibels (dB), a tissue axial resolution of 4.3 mum, and an acquisition rate of approximately 18,700 axial scans per second. For 3D analyses, a raster scan protocol of 256 x 256 axial scans covering a 2.8 x 2.8 mm disc area was used. Lamina cribrosa thickness was measured on 3D images using 3D image processing software. Correlation between lamina cribrosa thickness and mean deviation (MD) values obtained using static automatic perimetry were tested for statistical significance. Clarity of lamina cribrosa features, lamina cribrosa thickness, and MD values on static automatic perimetry. On 3D images, the lamina cribrosa appeared clearly as a highly reflective plate that was bowed posteriorly and contained many circular areas of low reflectivity. The dots of low reflectivity visible just beneath the anterior surface of the lamina cribrosa in en face cross-sections corresponded with dots representing lamina pores in color fundus photographs. The mean (+/-1 standard deviation) thickness of the lamina cribrosa was 190.5+/-52.7 mum (range, 80.5-329.0). Spearman rank testing and linear regression analysis showed that lamina cribrosa thickness correlated significantly with MD (Spearman sigma = 0.744; P<0.001; r(2) = 0.493; P<0.001). Different observers performed measurements of the lamina cribrosa thickness in SD-OCT cross-sectional images with high reproducibility (intraclass correlation coefficient = 0.784). These 3D SD-OCT imaging clearly demonstrated the 3D structure of the lamina cribrosa and allowed measurement of its thickness, which correlated significantly with visual field loss, in living patients with glaucoma. This noninvasive imaging technique should facilitate investigations of structural changes in the optic nerve head lamina cribrosa in eyes with optic nerve damage due to glaucoma. The authors have no proprietary or commercial interest in any materials discussed in this article.

  12. Structure from Motion Photogrammetry and Micro X-Ray Computed Tomography 3-D Reconstruction Data Fusion for Non-Destructive Conservation Documentation of Lunar Samples

    NASA Technical Reports Server (NTRS)

    Beaulieu, K. R.; Blumenfeld, E. H.; Liddle, D. A.; Oshel, E. R.; Evans, C. A.; Zeigler, R. A.; Righter, K.; Hanna, R. D.; Ketcham, R. A.

    2017-01-01

    Our team is developing a modern, cross-disciplinary approach to documentation and preservation of astromaterials, specifically lunar and meteorite samples stored at the Johnson Space Center (JSC) Lunar Sample Laboratory Facility. Apollo Lunar Sample 60639, collected as part of rake sample 60610 during the 3rd Extra-Vehicular Activity of the Apollo 16 mission in 1972, served as the first NASA-preserved lunar sample to be examined by our team in the development of a novel approach to internal and external sample visualization. Apollo Sample 60639 is classified as a breccia with a glass-coated side and pristine mare basalt and anorthosite clasts. The aim was to accurately register a 3-dimensional Micro X-Ray Computed Tomography (XCT)-derived internal composition data set and a Structure-From-Motion (SFM) Photogrammetry-derived high-fidelity, textured external polygonal model of Apollo Sample 60639. The developed process provided the means for accurate, comprehensive, non-destructive visualization of NASA's heritage lunar samples. The data products, to be ultimately served via an end-user web interface, will allow researchers and the public to interact with the unique heritage samples, providing a platform to "slice through" a photo-realistic rendering of a sample to analyze both its external visual and internal composition simultaneously.

  13. Three dimensional characterization of laser ablation craters using high resolution X-ray computed tomography

    NASA Astrophysics Data System (ADS)

    Galmed, A. H.; du Plessis, A.; le Roux, S. G.; Hartnick, E.; Von Bergmann, H.; Maaza, M.

    2018-01-01

    Laboratory X-ray computed tomography is an emerging technology for the 3D characterization and dimensional analysis of many types of materials. In this work we demonstrate the usefulness of this characterization method for the full three dimensional analysis of laser ablation craters, in the context of a laser induced breakdown spectroscopy setup. Laser induced breakdown spectroscopy relies on laser ablation for sampling the material of interest. We demonstrate here qualitatively (in images) and quantitatively (in terms of crater cone angles, depths, diameters and volume) laser ablation crater analysis in 3D for metal (aluminum) and rock (false gold ore). We show the effect of a Gaussian beam profile on the resulting crater geometry, as well as the first visual evidence of undercutting in the rock sample, most likely due to ejection of relatively large grains. The method holds promise for optimization of laser ablation setups especially for laser induced breakdown spectroscopy.

  14. Fresnel-propagated imaging for the study of human tooth dentin by partially coherent x-ray tomography

    NASA Astrophysics Data System (ADS)

    Zabler, S.; Riesemeier, H.; Fratzl, P.; Zaslansky, P.

    2006-09-01

    Recent methods of phase imaging in x-ray tomography allow the visualization of features that are not resolved in conventional absorption microtomography. Of these, the relatively simple setup needed to produce Fresnel-propagated tomograms appears to be well suited to probe tooth-dentin where composition as well as microstructure vary in a graded manner. By adapting analytical propagation approximations we provide predictions of the form of the interference patterns in the 3D images, which we compare to numerical simulations as well as data obtained from measurements of water immersed samples. Our observations reveal details of the tubular structure of dentin, and may be evaluated similarly to conventional absorption tomograms. We believe this exemplifies the power of Fresnel-propagated imaging as a form of 3D microscopy, well suited to quantify gradual microstructural-variations in teeth and similar tissues.

  15. Person and gesture tracking with smart stereo cameras

    NASA Astrophysics Data System (ADS)

    Gordon, Gaile; Chen, Xiangrong; Buck, Ron

    2008-02-01

    Physical security increasingly involves sophisticated, real-time visual tracking of a person's location inside a given environment, often in conjunction with biometrics and other security-related technologies. However, demanding real-world conditions like crowded rooms, changes in lighting and physical obstructions have proved incredibly challenging for 2D computer vision technology. In contrast, 3D imaging technology is not affected by constant changes in lighting and apparent color, and thus allows tracking accuracy to be maintained in dynamically lit environments. In addition, person tracking with a 3D stereo camera can provide the location and movement of each individual very precisely, even in a very crowded environment. 3D vision only requires that the subject be partially visible to a single stereo camera to be correctly tracked; multiple cameras are used to extend the system's operational footprint, and to contend with heavy occlusion. A successful person tracking system, must not only perform visual analysis robustly, but also be small, cheap and consume relatively little power. The TYZX Embedded 3D Vision systems are perfectly suited to provide the low power, small footprint, and low cost points required by these types of volume applications. Several security-focused organizations, including the U.S Government, have deployed TYZX 3D stereo vision systems in security applications. 3D image data is also advantageous in the related application area of gesture tracking. Visual (uninstrumented) tracking of natural hand gestures and movement provides new opportunities for interactive control including: video gaming, location based entertainment, and interactive displays. 2D images have been used to extract the location of hands within a plane, but 3D hand location enables a much broader range of interactive applications. In this paper, we provide some background on the TYZX smart stereo cameras platform, describe the person tracking and gesture tracking systems implemented on this platform, and discuss some deployed applications.

  16. Improving Low-dose Cardiac CT Images based on 3D Sparse Representation

    NASA Astrophysics Data System (ADS)

    Shi, Luyao; Hu, Yining; Chen, Yang; Yin, Xindao; Shu, Huazhong; Luo, Limin; Coatrieux, Jean-Louis

    2016-03-01

    Cardiac computed tomography (CCT) is a reliable and accurate tool for diagnosis of coronary artery diseases and is also frequently used in surgery guidance. Low-dose scans should be considered in order to alleviate the harm to patients caused by X-ray radiation. However, low dose CT (LDCT) images tend to be degraded by quantum noise and streak artifacts. In order to improve the cardiac LDCT image quality, a 3D sparse representation-based processing (3D SR) is proposed by exploiting the sparsity and regularity of 3D anatomical features in CCT. The proposed method was evaluated by a clinical study of 14 patients. The performance of the proposed method was compared to the 2D spares representation-based processing (2D SR) and the state-of-the-art noise reduction algorithm BM4D. The visual assessment, quantitative assessment and qualitative assessment results show that the proposed approach can lead to effective noise/artifact suppression and detail preservation. Compared to the other two tested methods, 3D SR method can obtain results with image quality most close to the reference standard dose CT (SDCT) images.

  17. An Assessment of Gigabit Ethernet Technology and Its Applications at the NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Bakes, Catherine Murphy; Kim, Chan M.; Ramos, Calvin T.

    2000-01-01

    This paper describes Gigabit Ethernet and its role in supporting R&D programs at NASA Glenn. These programs require an advanced high-speed network capable of transporting multimedia traffic, including real-time visualization, high- resolution graphics, and scientific data. GigE is a 1 Gbps extension to 10 and 100 Mbps Ethernet. The IEEE 802.3z and 802.3ab standards define the MAC layer and 1000BASE-X and 1000BASE-T physical layer specifications for GigE. GigE switches and buffered distributors support IEEE 802.3x flow control. The paper also compares GigE with ATM in terms of quality of service, data rate, throughput, scalability, interoperability, network management, and cost of ownership.

  18. Visualization and correction of automated segmentation, tracking and lineaging from 5-D stem cell image sequences.

    PubMed

    Wait, Eric; Winter, Mark; Bjornsson, Chris; Kokovay, Erzsebet; Wang, Yue; Goderie, Susan; Temple, Sally; Cohen, Andrew R

    2014-10-03

    Neural stem cells are motile and proliferative cells that undergo mitosis, dividing to produce daughter cells and ultimately generating differentiated neurons and glia. Understanding the mechanisms controlling neural stem cell proliferation and differentiation will play a key role in the emerging fields of regenerative medicine and cancer therapeutics. Stem cell studies in vitro from 2-D image data are well established. Visualizing and analyzing large three dimensional images of intact tissue is a challenging task. It becomes more difficult as the dimensionality of the image data increases to include time and additional fluorescence channels. There is a pressing need for 5-D image analysis and visualization tools to study cellular dynamics in the intact niche and to quantify the role that environmental factors play in determining cell fate. We present an application that integrates visualization and quantitative analysis of 5-D (x,y,z,t,channel) and large montage confocal fluorescence microscopy images. The image sequences show stem cells together with blood vessels, enabling quantification of the dynamic behaviors of stem cells in relation to their vascular niche, with applications in developmental and cancer biology. Our application automatically segments, tracks, and lineages the image sequence data and then allows the user to view and edit the results of automated algorithms in a stereoscopic 3-D window while simultaneously viewing the stem cell lineage tree in a 2-D window. Using the GPU to store and render the image sequence data enables a hybrid computational approach. An inference-based approach utilizing user-provided edits to automatically correct related mistakes executes interactively on the system CPU while the GPU handles 3-D visualization tasks. By exploiting commodity computer gaming hardware, we have developed an application that can be run in the laboratory to facilitate rapid iteration through biological experiments. We combine unsupervised image analysis algorithms with an interactive visualization of the results. Our validation interface allows for each data set to be corrected to 100% accuracy, ensuring that downstream data analysis is accurate and verifiable. Our tool is the first to combine all of these aspects, leveraging the synergies obtained by utilizing validation information from stereo visualization to improve the low level image processing tasks.

  19. How much camera separation should be used for the capture and presentation of 3D stereoscopic imagery on binocular HMDs?

    NASA Astrophysics Data System (ADS)

    McIntire, John; Geiselman, Eric; Heft, Eric; Havig, Paul

    2011-06-01

    Designers, researchers, and users of binocular stereoscopic head- or helmet-mounted displays (HMDs) face the tricky issue of what imagery to present in their particular displays, and how to do so effectively. Stereoscopic imagery must often be created in-house with a 3D graphics program or from within a 3D virtual environment, or stereoscopic photos/videos must be carefully captured, perhaps for relaying to an operator in a teleoperative system. In such situations, the question arises as to what camera separation (real or virtual) is appropriate or desirable for end-users and operators. We review some of the relevant literature regarding the question of stereo pair camera separation using deskmounted or larger scale stereoscopic displays, and employ our findings to potential HMD applications, including command & control, teleoperation, information and scientific visualization, and entertainment.

  20. Conditions that influence the accuracy of anthropometric parameter estimation for human body segments using shape-from-silhouette

    NASA Astrophysics Data System (ADS)

    Mundermann, Lars; Mundermann, Annegret; Chaudhari, Ajit M.; Andriacchi, Thomas P.

    2005-01-01

    Anthropometric parameters are fundamental for a wide variety of applications in biomechanics, anthropology, medicine and sports. Recent technological advancements provide methods for constructing 3D surfaces directly. Of these new technologies, visual hull construction may be the most cost-effective yet sufficiently accurate method. However, the conditions influencing the accuracy of anthropometric measurements based on visual hull reconstruction are unknown. The purpose of this study was to evaluate the conditions that influence the accuracy of 3D shape-from-silhouette reconstruction of body segments dependent on number of cameras, camera resolution and object contours. The results demonstrate that the visual hulls lacked accuracy in concave regions and narrow spaces, but setups with a high number of cameras reconstructed a human form with an average accuracy of 1.0 mm. In general, setups with less than 8 cameras yielded largely inaccurate visual hull constructions, while setups with 16 and more cameras provided good volume estimations. Body segment volumes were obtained with an average error of 10% at a 640x480 resolution using 8 cameras. Changes in resolution did not significantly affect the average error. However, substantial decreases in error were observed with increasing number of cameras (33.3% using 4 cameras; 10.5% using 8 cameras; 4.1% using 16 cameras; 1.2% using 64 cameras).

  1. Investigation of visual fatigue/discomfort generated by S3D video using eye-tracking data

    NASA Astrophysics Data System (ADS)

    Iatsun, Iana; Larabi, Mohamed-Chaker; Fernandez-Maloigne, Christine

    2013-03-01

    Stereoscopic 3D is undoubtedly one of the most attractive content. It has been deployed intensively during the last decade through movies and games. Among the advantages of 3D are the strong involvement of viewers and the increased feeling of presence. However, the sanitary e ects that can be generated by 3D are still not precisely known. For example, visual fatigue and visual discomfort are among symptoms that an observer may feel. In this paper, we propose an investigation of visual fatigue generated by 3D video watching, with the help of eye-tracking. From one side, a questionnaire, with the most frequent symptoms linked with 3D, is used in order to measure their variation over time. From the other side, visual characteristics such as pupil diameter, eye movements ( xations and saccades) and eye blinking have been explored thanks to data provided by the eye-tracker. The statistical analysis showed an important link between blinking duration and number of saccades with visual fatigue while pupil diameter and xations are not precise enough and are highly dependent on content. Finally, time and content play an important role in the growth of visual fatigue due to 3D watching.

  2. Networking for large-scale science: infrastructure, provisioning, transport and application mapping

    NASA Astrophysics Data System (ADS)

    Rao, Nageswara S.; Carter, Steven M.; Wu, Qishi; Wing, William R.; Zhu, Mengxia; Mezzacappa, Anthony; Veeraraghavan, Malathi; Blondin, John M.

    2005-01-01

    Large-scale science computations and experiments require unprecedented network capabilities in the form of large bandwidth and dynamically stable connections to support data transfers, interactive visualizations, and monitoring and steering operations. A number of component technologies dealing with the infrastructure, provisioning, transport and application mappings must be developed and/or optimized to achieve these capabilities. We present a brief account of the following technologies that contribute toward achieving these network capabilities: (a) DOE UltraScienceNet and NSF CHEETAH network testbeds that provide on-demand and scheduled dedicated network connections; (b) experimental results on transport protocols that achieve close to 100% utilization on dedicated 1Gbps wide-area channels; (c) a scheme for optimally mapping a visualization pipeline onto a network to minimize the end-to-end delays; and (d) interconnect configuration and protocols that provides multiple Gbps flows from Cray X1 to external hosts.

  3. The effects of stereo disparity on the behavioural and electrophysiological correlates of perception of audio-visual motion in depth.

    PubMed

    Harrison, Neil R; Witheridge, Sian; Makin, Alexis; Wuerger, Sophie M; Pegna, Alan J; Meyer, Georg F

    2015-11-01

    Motion is represented by low-level signals, such as size-expansion in vision or loudness changes in the auditory modality. The visual and auditory signals from the same object or event may be integrated and facilitate detection. We explored behavioural and electrophysiological correlates of congruent and incongruent audio-visual depth motion in conditions where auditory level changes, visual expansion, and visual disparity cues were manipulated. In Experiment 1 participants discriminated auditory motion direction whilst viewing looming or receding, 2D or 3D, visual stimuli. Responses were faster and more accurate for congruent than for incongruent audio-visual cues, and the congruency effect (i.e., difference between incongruent and congruent conditions) was larger for visual 3D cues compared to 2D cues. In Experiment 2, event-related potentials (ERPs) were collected during presentation of the 2D and 3D, looming and receding, audio-visual stimuli, while participants detected an infrequent deviant sound. Our main finding was that audio-visual congruity was affected by retinal disparity at an early processing stage (135-160ms) over occipito-parietal scalp. Topographic analyses suggested that similar brain networks were activated for the 2D and 3D congruity effects, but that cortical responses were stronger in the 3D condition. Differences between congruent and incongruent conditions were observed between 140-200ms, 220-280ms, and 350-500ms after stimulus onset. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Virtual reality on the web: the potentials of different methodologies and visualization techniques for scientific research and medical education.

    PubMed

    Kling-Petersen, T; Pascher, R; Rydmark, M

    1999-01-01

    Academic and medical imaging are increasingly using computer based 3D reconstruction and/or visualization. Three-dimensional interactive models play a major role in areas such as preclinical medical education, clinical visualization and medical research. While 3D is comparably easy to do on a high end workstations, distribution and use of interactive 3D graphics necessitate the use of personal computers and the web. Several new techniques have been demonstrated providing interactive 3D via a web browser thereby allowing a limited version of VR to be experienced by a larger majority of students, medical practitioners and researchers. These techniques include QuickTimeVR2 (QTVR), VRML2, QuickDraw3D, OpenGL and Java3D. In order to test the usability of the different techniques, Mednet have initiated a number of projects designed to evaluate the potentials of 3D techniques for scientific reporting, clinical visualization and medical education. These include datasets created by manual tracing followed by triangulation, smoothing and 3D visualization, MRI or high-resolution laserscanning. Preliminary results indicate that both VRML and QTVR fulfills most of the requirements of web based, interactive 3D visualization, whereas QuickDraw3D is too limited. Presently, the JAVA 3D has not yet reached a level where in depth testing is possible. The use of high-resolution laserscanning is an important addition to 3D digitization.

  5. Multi-wavelength transceiver integration on SOI for high-performance computing system applications

    NASA Astrophysics Data System (ADS)

    Aalto, Timo; Harjanne, Mikko; Ylinen, Sami; Kapulainen, Markku; Vehmas, Tapani; Cherchi, Matteo; Neumeyr, Christian; Ortsiefer, Markus; Malacarne, Antonio

    2015-03-01

    We present a vision for transceiver integration on a 3 μm SOI waveguide platform for systems scalable to Pb/s. We also present experimental results from the first building blocks developed in the EU-funded RAPIDO project. At 1.3 μm wavelength 80 Gb/s per wavelength is to be achieved using hybrid integration of III-V optoelectronics on SOI. Goals include athermal operation, low-loss I/O coupling, advanced modulation formats and packet switching. An example of the design results is an interposer chip that consists of 12 μm thick SOI waveguides locally tapered down to 3 μm to provide low-loss coupling between an optical single-mode fiber array and the 3 μm SOI chip. First example of experimental results is a 4x4 cyclic AWGs with 5 nm channel spacing, 0.4 dB/facet fiber coupling loss, 3.5 dB center-tocenter loss, and -23 dB adjacent channel crosstalk in 3.5x1.5 mm2 footprint. The second example result is a new VCSEL design that was demonstrated to have up to 40 Gb/s operation at 1.55 μm.

  6. Improved Surgery Planning Using 3-D Printing: a Case Study.

    PubMed

    Singhal, A J; Shetty, V; Bhagavan, K R; Ragothaman, Ananthan; Shetty, V; Koneru, Ganesh; Agarwala, M

    2016-04-01

    The role of 3-D printing is presented for improved patient-specific surgery planning. Key benefits are time saved and surgery outcome. Two hard-tissue surgery models were 3-D printed, for orthopedic, pelvic surgery, and craniofacial surgery. We discuss software data conversion in computed tomography (CT)/magnetic resonance (MR) medical image for 3-D printing. 3-D printed models save time in surgery planning and help visualize complex pre-operative anatomy. Time saved in surgery planning can be as much as two thirds. In addition to improved surgery accuracy, 3-D printing presents opportunity in materials research. Other hard-tissue and soft-tissue cases in maxillofacial, abdominal, thoracic, cardiac, orthodontics, and neurosurgery are considered. We recommend using 3-D printing as standard protocol for surgery planning and for teaching surgery practices. A quick turnaround time of a 3-D printed surgery model, in improved accuracy in surgery planning, is helpful for the surgery team. It is recommended that these costs be within 20 % of the total surgery budget.

  7. Ultrahigh-definition dynamic 3D holographic display by active control of volume speckle fields

    NASA Astrophysics Data System (ADS)

    Yu, Hyeonseung; Lee, Kyeoreh; Park, Jongchan; Park, Yongkeun

    2017-01-01

    Holographic displays generate realistic 3D images that can be viewed without the need for any visual aids. They operate by generating carefully tailored light fields that replicate how humans see an actual environment. However, the realization of high-performance, dynamic 3D holographic displays has been hindered by the capabilities of present wavefront modulator technology. In particular, spatial light modulators have a small diffraction angle range and limited pixel number limiting the viewing angle and image size of a holographic 3D display. Here, we present an alternative method to generate dynamic 3D images by controlling volume speckle fields significantly enhancing image definition. We use this approach to demonstrate a dynamic display of micrometre-sized optical foci in a volume of 8 mm × 8 mm × 20 mm.

  8. Registering 2D and 3D imaging data of bone during healing.

    PubMed

    Hoerth, Rebecca M; Baum, Daniel; Knötel, David; Prohaska, Steffen; Willie, Bettina M; Duda, Georg N; Hege, Hans-Christian; Fratzl, Peter; Wagermaier, Wolfgang

    2015-04-01

    PURPOSE/AIMS OF THE STUDY: Bone's hierarchical structure can be visualized using a variety of methods. Many techniques, such as light and electron microscopy generate two-dimensional (2D) images, while micro-computed tomography (µCT) allows a direct representation of the three-dimensional (3D) structure. In addition, different methods provide complementary structural information, such as the arrangement of organic or inorganic compounds. The overall aim of the present study is to answer bone research questions by linking information of different 2D and 3D imaging techniques. A great challenge in combining different methods arises from the fact that they usually reflect different characteristics of the real structure. We investigated bone during healing by means of µCT and a couple of 2D methods. Backscattered electron images were used to qualitatively evaluate the tissue's calcium content and served as a position map for other experimental data. Nanoindentation and X-ray scattering experiments were performed to visualize mechanical and structural properties. We present an approach for the registration of 2D data in a 3D µCT reference frame, where scanning electron microscopies serve as a methodic link. Backscattered electron images are perfectly suited for registration into µCT reference frames, since both show structures based on the same physical principles. We introduce specific registration tools that have been developed to perform the registration process in a semi-automatic way. By applying this routine, we were able to exactly locate structural information (e.g. mineral particle properties) in the 3D bone volume. In bone healing studies this will help to better understand basic formation, remodeling and mineralization processes.

  9. Imaging and characterizing cells using tomography

    PubMed Central

    Do, Myan; Isaacson, Samuel A.; McDermott, Gerry; Le Gros, Mark A.; Larabell, Carolyn A.

    2015-01-01

    We can learn much about cell function by imaging and quantifying sub-cellular structures, especially if this is done non-destructively without altering said structures. Soft x-ray tomography (SXT) is a high-resolution imaging technique for visualizing cells and their interior structure in 3D. A tomogram of the cell, reconstructed from a series of 2D projection images, can be easily segmented and analyzed. SXT has a very high specimen throughput compared to other high-resolution structure imaging modalities; for example, tomographic data for reconstructing an entire eukaryotic cell is acquired in a matter of minutes. SXT visualizes cells without the need for chemical fixation, dehydration, or staining of the specimen. As a result, the SXT reconstructions are close representations of cells in their native state. SXT is applicable to most cell types. The deep penetration of soft x-rays allows cells, even mammalian cells, to be imaged without being sectioned. Image contrast in SXT is generated by the differential attenuation soft x-ray illumination as it passes through the specimen. Accordingly, each voxel in the tomographic reconstruction has a measured linear absorption coefficient (LAC) value. LAC values are quantitative and give rise to each sub-cellular component having a characteristic LAC profile, allowing organelles to be identified and segmented from the milieu of other cell contents. In this chapter, we describe the fundamentals of SXT imaging and how this technique can answer real world questions in the study of the nucleus. We also describe the development of correlative methods for the localization of specific molecules in a SXT reconstruction. The combination of fluorescence and SXT data acquired from the same specimen produces composite 3D images, rich with detailed information on the inner workings of cells. PMID:25602704

  10. Low-dose intrathecal fluorescein for diagnosis of cerebrospinal fluid rhinorrhea using the scanning fiber endoscope in the human nasal cavities

    NASA Astrophysics Data System (ADS)

    Hou, Vivian W.; Davis, Calvin G.; Davis, Greg E.; Seibel, Eric J.

    2016-03-01

    Intrathecal fluorescein (ITF) enhances detection of cerebrospinal fluid rhinorrhea (CSFR). Clinically administered doses fall in the range of 0.1ml to 0.5ml of 5% to 10% fluorescein (1.3×10-3M to 1.3×10-2M). Though uncommon, significant morbidities associated with high doses of fluorescein have been reported. High concentrations are necessary for white light visual assessment; in contrast, fluorescent imaging enhances signal contrast and requires lower ITF concentrations for visualization. The ultrathin and flexible, multimodal scanning fiber endoscope (SFE) can visualize nanomolar concentrations of fluorescein as pseudocolor over reflectance, video-rate imaging. The application of the SFE for CSFR detection was assessed in a cadaver study. Briefly, 10μM (1×10-5M) fluorescein, 100X-1000X less than the standard clinical dose, was injected intra-cranially into the epidural space through an orbital roof puncture. The resulting rhinorrhea was assessed with a conventional, rigid ENT scope and second with the SFE in both video reflectance and multimodal fluorescent imaging modes. Neither system could visualize the 10μM ITF during white light imaging however the nanomolar sensitive SFE visualized the rhinorrhea during fluorescent imaging. Despite the low concentration used, a target-to-background ratio of 5.6 +/- 2.7 was achieved. To demonstrate SFE guidance of CSFR detection and repair, de-identified patient computed tomography (CT) scans were used to generate 3D printed phantoms. Cases were selected for unique anatomical features and overall clinical difficulty as determined by an experienced ENT clinician (GED). The sensitivity and minimally invasive nature of the SFE provide a unique platform for enhancing diagnosis and monitoring interventions in surgical endoscopic approaches into the sinuses.

  11. Managing multiple image stacks from confocal laser scanning microscopy

    NASA Astrophysics Data System (ADS)

    Zerbe, Joerg; Goetze, Christian H.; Zuschratter, Werner

    1999-05-01

    A major goal in neuroanatomy is to obtain precise information about the functional organization of neuronal assemblies and their interconnections. Therefore, the analysis of histological sections frequently requires high resolution images in combination with an overview about the structure. To overcome this conflict we have previously introduced a software for the automatic acquisition of multiple image stacks (3D-MISA) in confocal laser scanning microscopy. Here, we describe a Windows NT based software for fast and easy navigation through the multiple images stacks (MIS-browser), the visualization of individual channels and layers and the selection of user defined subregions. In addition, the MIS browser provides useful tools for the visualization and evaluation of the datavolume, as for instance brightness and contrast corrections of individual layers and channels. Moreover, it includes a maximum intensity projection, panning and zoom in/out functions within selected channels or focal planes (x/y) and tracking along the z-axis. The import module accepts any tiff-format and reconstructs the original image arrangement after the user has defined the sequence of images in x/y and z and the number of channels. The implemented export module allows storage of user defined subregions (new single image stacks) for further 3D-reconstruction and evaluation.

  12. Application of x-ray nano-particulate markers for the visualization of intermediate layers and interfaces using scanning electron microscopy

    NASA Astrophysics Data System (ADS)

    Bessudnova, Nadezda O.; Bilenko, David I.; Zakharevich, Andrey M.

    2012-03-01

    In this study the methodology of biological sample preparation for dental research using SEM/EDX has been elaborated. (1)The original cutting equipment supplied with 3D user-controlled sample fixation and an adjustable cooling system has been designed and evaluated. (2) A new approach to the root dentine drying procedure has been developed to preserve structure peculiarities of root dentine. (3) A novel adhesive system with embedded X-Ray nanoparticulate markers has been designed. (4)The technique allowing for visualization of bonding resins, interfaces and intermediate layers between tooth hard tissues and restorative materials of endodontically treated teeth using the X-ray nano-particulate markers has been developed and approved. These methods and approaches were used to compare the objective depth of penetration of adhesive systems of different generations in root dentine. It has been shown that the depth of penetration in dentine is less for adhesive systems of generation VI in comparison with bonding resins of generation V, which is in agreement with theoretical evidence. The depth of penetration depends on the correlation between the direction of dentinal tubules, bonding resin delivery and gravity.

  13. Advances in LADAR Components and Subsystems at Raytheon

    NASA Technical Reports Server (NTRS)

    Jack, Michael; Chapman, George; Edwards, John; McKeag, William; Veeder, Tricia; Wehner, Justin; Roberts, Tom; Robinson, Tom; Neisz, James; Andressen, Cliff; hide

    2012-01-01

    Raytheon is developing NIR sensor chip assemblies (SCAs) for scanning and staring 3D LADAR systems. High sensitivity is obtained by integrating high performance detectors with gain, i.e., APDs with very low noise Readout Integrated Circuits (ROICs). Unique aspects of these designs include: independent acquisition (non-gated) of pulse returns, multiple pulse returns with both time and intensity reported to enable full 3D reconstruction of the image. Recent breakthrough in device design has resulted in HgCdTe APDs operating at 300K with essentially no excess noise to gains in excess of 100, low NEP <1nW and GHz bandwidths and have demonstrated linear mode photon counting. SCAs utilizing these high performance APDs have been integrated and demonstrated excellent spatial and range resolution enabling detailed 3D imagery both at short range and long ranges. In the following we will review progress in real-time 3D LADAR imaging receiver products in three areas: (1) scanning 256 x 4 configuration for the Multi-Mode Sensor Seeker (MMSS) program and (2) staring 256 x 256 configuration for the Autonomous Landing and Hazard Avoidance Technology (ALHAT) lunar landing mission and (3) Photon-Counting SCAs which have demonstrated a dramatic reduction in dark count rate due to improved design, operation and processing.

  14. [Three-dimensional morphological modeling and visualization of wheat root system].

    PubMed

    Tan, Feng; Tang, Liang; Hu, Jun-Cheng; Jiang, Hai-Yan; Cao, Wei-Xing; Zhu, Yan

    2011-01-01

    Crop three-dimensional (3D) morphological modeling and visualization is an important part of digital plant study. This paper aimed to develop a 3D morphological model of wheat root system based on the parameters of wheat root morphological features, and to realize the visualization of wheat root growth. According to the framework of visualization technology for wheat root growth, a 3D visualization model of wheat root axis, including root axis growth model, branch geometric model, and root axis curve model, was developed firstly. Then, by integrating root topology, the corresponding pixel was determined, and the whole wheat root system was three-dimensionally re-constructed by using the morphological feature parameters in the root morphological model. Finally, based on the platform of OpenGL, and by integrating the technologies of texture mapping, lighting rendering, and collision detection, the 3D visualization of wheat root growth was realized. The 3D output of wheat root system from the model was vivid, which could realize the 3D root system visualization of different wheat cultivars under different water regimes and nitrogen application rates. This study could lay a technical foundation for further development of an integral visualization system of wheat plant.

  15. Soft X-ray Foucault test: A path to diffraction-limited imaging

    NASA Astrophysics Data System (ADS)

    Ray-Chaudhuri, A. K.; Ng, W.; Liang, S.; Cerrina, F.

    1994-08-01

    We present the development of a soft X-ray Foucault test capable of characterizing the imaging properties of a soft X-ray optical system at its operational wavelength and its operational configuration. This optical test enables direct visual inspection of imaging aberrations and provides real-time feedback for the alignment of high resolution soft X-ray optical systems. A first application of this optical test was carried out on a Mo-Si multilayer-coated Schwarzschild objective as part of the MAXIMUM project. Results from the alignment procedure are presented as well as the possibility for testing in the hard X-ray regime.

  16. $X(3873$ and $Y(4140)$ using diquark-antidiquark operators with lattice QCD

    DOE PAGES

    Padmanath, M.; Lang, C.  B.; Prelovsek Komelj, Sasa

    2015-08-01

    We perform a lattice study of charmonium-like mesons withmore » $$J^{PC}=1^{++}$$ and three quark contents $$\\bar cc \\bar du$$, $$\\bar cc(\\bar uu+\\bar dd)$$ and $$\\bar cc \\bar ss$$, where the later two can mix with $$\\bar cc$$. This simulation with $$N_f=2$$ and $$m_\\pi=266$$ MeV aims at the possible signatures of four-quark exotic states. We utilize a large basis of $$\\bar cc$$, two-meson and diquark-antidiquark interpolating fields, with diquarks in both anti-triplet and sextet color representations. A lattice candidate for X(3872) with I=0 is observed very close to the experimental state only if both $$\\bar cc$$ and $$D\\bar D^*$$ interpolators are included; the candidate is not found if diquark-antidiquark and $$D\\bar D^*$$ are used in the absence of $$\\bar cc$$. No candidate for neutral or charged X(3872), or any other exotic candidates are found in the I=1 channel. We also do not find signatures of exotic $$\\bar cc\\bar ss$$ candidates below 4.3 GeV, such as Y(4140). Possible physics and methodology related reasons for that are discussed. Along the way, we present the diquark-antidiquark operators as linear combinations of the two-meson operators via the Fierz transformations.« less

  17. CAVE2: a hybrid reality environment for immersive simulation and information analysis

    NASA Astrophysics Data System (ADS)

    Febretti, Alessandro; Nishimoto, Arthur; Thigpen, Terrance; Talandis, Jonas; Long, Lance; Pirtle, J. D.; Peterka, Tom; Verlo, Alan; Brown, Maxine; Plepys, Dana; Sandin, Dan; Renambot, Luc; Johnson, Andrew; Leigh, Jason

    2013-03-01

    Hybrid Reality Environments represent a new kind of visualization spaces that blur the line between virtual environments and high resolution tiled display walls. This paper outlines the design and implementation of the CAVE2TM Hybrid Reality Environment. CAVE2 is the world's first near-seamless flat-panel-based, surround-screen immersive system. Unique to CAVE2 is that it will enable users to simultaneously view both 2D and 3D information, providing more flexibility for mixed media applications. CAVE2 is a cylindrical system of 24 feet in diameter and 8 feet tall, and consists of 72 near-seamless, off-axisoptimized passive stereo LCD panels, creating an approximately 320 degree panoramic environment for displaying information at 37 Megapixels (in stereoscopic 3D) or 74 Megapixels in 2D and at a horizontal visual acuity of 20/20. Custom LCD panels with shifted polarizers were built so the images in the top and bottom rows of LCDs are optimized for vertical off-center viewing- allowing viewers to come closer to the displays while minimizing ghosting. CAVE2 is designed to support multiple operating modes. In the Fully Immersive mode, the entire room can be dedicated to one virtual simulation. In 2D model, the room can operate like a traditional tiled display wall enabling users to work with large numbers of documents at the same time. In the Hybrid mode, a mixture of both 2D and 3D applications can be simultaneously supported. The ability to treat immersive work spaces in this Hybrid way has never been achieved before, and leverages the special abilities of CAVE2 to enable researchers to seamlessly interact with large collections of 2D and 3D data. To realize this hybrid ability, we merged the Scalable Adaptive Graphics Environment (SAGE) - a system for supporting 2D tiled displays, with Omegalib - a virtual reality middleware supporting OpenGL, OpenSceneGraph and Vtk applications.

  18. Study on choroidal neovascularization with anti-VEGF treatment in the mouse retina using optical coherence tomography angiography (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Park, Jang Ryul; Choi, WooJhon; Kim, Jaeryung; Hong, Hye Kyong; Kim, Yongjoo; Hwang, Yoonha; Park, Sang Jun; Woo, Se Joon; Kim, Pilhan; Park, Kyu Hyung; Koh, Gou Young; Oh, Wang-Yuhl

    2017-02-01

    To understand the pathogenesis of ophthalmic disease, utilizing small animal models such as mouse is necessary because of their ease of maintenance and availability. For identifying pathophysiology and drug development of retinal diseases in mouse model, optical coherence tomography angiography (OCTA) is promising imaging modality visualizing not only microstructure but also microvasculature. In this study, we serially imaged 3D structure and angiography of laser-induced choroidal neovascularization (CNV) in the mouse retina with/without anti-VEGF treatment. Also, the volume changes of CNV and avascular region in choroid layer are measured for identifying effects of anti-VEGF. A lab-built high-speed OCTA prototype using the wavelength-swept laser centered at 1040 nm with 230 kHz A-scan rate acquired 3-D volumetric data consisted of 1024 x 1024 x 3 A-scans. The OCTA scanned 1.7 mm x 1.7 mm area around ONH. For obtaining angiography, amplitude decorrelation from 3 consecutive B-scans at each position was generated. Seven days after the laser photocoagulation at mouse retina for generation of the laser-induced CNV, intravitreal administration of Fc and VEGF-Trap was given in the therapeutic arm. The OCTA were performed at 6, 14, 21 and 35 days after laser photocoagulation. Vasculatures of inner retina, outer retina and choroid layers were separately visualized after RPE flattening and layer segmentation. To investigate therapeutic effects of anti-VEGF treatment, the relative area and volume of CNV in outer retina layer is measured. Also, total volume of avascular zone surrounding the laser injury site in choroid layer is also analyzed.

  19. Effect of non-feeding period length on the intermittent operation of UASB reactors treating dairy effluents.

    PubMed

    Coelho, N M; Rodrigues, A A; Arroja, L M; Capela, I F

    2007-02-01

    Recent environmental concerns have prompted a re-evaluation of conventional management strategies and refueled the search of innovative waste management practices. In this sense, the anaerobic digestion of both fat and the remaining complex organic matter present in dairy wastewaters is attractive, although the continuous operation of high rate anaerobic processes treating this type of wastewaters causes the failure of the process. This work accesses the influence of non-feeding period length on the intermittent operation of mesophilic UASB reactors treating dairy wastewater, in order to allow the biological degradation to catch up with adsorption phenomenon. During the experiments, two UASB reactors were subject to three organic loading rates, ranging from 6 to 12 g(COD) x L(-1) x d(-1), with the same daily load applied to both reactors, each one with a different non-feeding period. Both reactors showed good COD removal efficiencies (87-92%). A material balance for COD in the reactors during the feeding and non-feeding periods showed the importance of the feedless period, which allowed the biomass to degrade substrate that was accumulated during the feeding period. The reactor with the longest non-feeding period had a better performance, which resulted in a higher methane production and adsorption capacity for the same organic load applied with a consequent less accumulation of substrate into the biomass. In addition, both reactors had a stable operation for the organic load of 12 g(COD) x L(-1) x d(-1), which is higher than the maximum applicable load reported in literature for continuous systems (3-6 g(COD) x L(-1) x d(-1)). (c) 2006 Wiley Periodicals, Inc.

  20. Oxidation/reduction reactions at the metal contact-TlBr interface: an x-ray photoelectron spectroscopy study

    NASA Astrophysics Data System (ADS)

    Nelson, A. J.; Swanberg, E. L.; Voss, L. F.; Graff, R. T.; Conway, A. M.; Nikolic, R. J.; Payne, S. A.; Kim, H.; Cirignano, L.; Shah, K.

    2014-09-01

    TlBr radiation detector operation degrades with time at room temperature and is thought to be due to electromigration of Tl and Br vacancies within the crystal as well as the metal contacts migrating into the TlBr crystal itself due to electrochemical reactions at the metal/TlBr interface. X-ray photoemission spectroscopy (XPS) was used to investigate the metal contact surface/interfacial structure on TlBr devices. Device-grade TlBr was polished and subjected to a 32% HCl etch to remove surface damage prior to Mo or Pt contact deposition. High-resolution photoemission measurements on the Tl 4f, Br 3d, Cl 2p, Mo 3d and Pt 4f core lines were used to evaluate surface chemistry and non-equilibrium interfacial diffusion. Results indicate that anion substitution at the TlBr surface due to the HCl etch forms TlBr1-xClx with consequent formation of a shallow heterojunction. In addition, a reduction of Tl1+ to Tl0 is observed at the metal contacts after device operation in both air and N2 at ambient temperature. Understanding contact/device degradation versus operating environment is useful for improving radiation detector performance.

  1. Analyzing microtomography data with Python and the scikit-image library.

    PubMed

    Gouillart, Emmanuelle; Nunez-Iglesias, Juan; van der Walt, Stéfan

    2017-01-01

    The exploration and processing of images is a vital aspect of the scientific workflows of many X-ray imaging modalities. Users require tools that combine interactivity, versatility, and performance. scikit-image is an open-source image processing toolkit for the Python language that supports a large variety of file formats and is compatible with 2D and 3D images. The toolkit exposes a simple programming interface, with thematic modules grouping functions according to their purpose, such as image restoration, segmentation, and measurements. scikit-image users benefit from a rich scientific Python ecosystem that contains many powerful libraries for tasks such as visualization or machine learning. scikit-image combines a gentle learning curve, versatile image processing capabilities, and the scalable performance required for the high-throughput analysis of X-ray imaging data.

  2. Thoracoscopic anatomical lung segmentectomy using 3D computed tomography simulation without tumour markings for non-palpable and non-visualized small lung nodules.

    PubMed

    Kato, Hirohisa; Oizumi, Hiroyuki; Suzuki, Jun; Hamada, Akira; Watarai, Hikaru; Sadahiro, Mitsuaki

    2017-09-01

    Although wedge resection can be curative for small lung tumours, tumour marking is sometimes required for resection of non-palpable or visually undetectable lung nodules as a method for identification of tumours. Tumour marking sometimes fails and occasionally causes serious complications. We have performed many thoracoscopic segmentectomies using 3D computed tomography simulation for undetectable small lung tumours without any tumour markings. The aim of this study was to investigate whether thoracoscopic segmentectomy planned with 3D computed tomography simulation could precisely remove non-palpable and visually undetectable tumours. Between January 2012 and March 2016, 58 patients underwent thoracoscopic segmentectomy using 3D computed tomography simulation for non-palpable, visually undetectable tumours. Surgical outcomes were evaluated. A total of 35, 14 and 9 patients underwent segmentectomy, subsegmentectomy and segmentectomy combined with adjacent subsegmentectomy, respectively. All tumours were correctly resected without tumour marking. The median tumour size and distance from the visceral pleura was 14 ± 5.2 mm (range 5-27 mm) and 11.6 mm (range 1-38.8 mm), respectively. Median values related to the procedures were operative time, 176 min (range 83-370 min); blood loss, 43 ml (range 0-419 ml); duration of chest tube placement, 1 day (range 1-8 days); and postoperative hospital stay, 5 days (range 3-12 days). Two cases were converted to open thoracotomy due to bleeding. Three cases required pleurodesis for pleural fistula. No recurrences occurred during the mean follow-up period of 44.4 months (range 5-53 months). Thoracoscopic segmentectomy using 3D computed tomography simulation was feasible and could be performed to resect undetectable tumours with no tumour markings. © The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  3. Steam tables for pure water as an ActiveX component in Visual Basic 6.0

    NASA Astrophysics Data System (ADS)

    Verma, Mahendra P.

    2003-11-01

    The IAPWS-95 formulation for the thermodynamic properties of pure water was implemented as an ActiveX component ( SteamTables) in Visual Basic 6.0. For input parameters as temperature ( T=190-2000 K) and pressure ( P=3.23×10 -8-10,000 MPa) the program SteamTables calculates the following properties: volume ( V), density ( D), compressibility factor ( Z0), internal energy ( U), enthalpy ( H), Gibbs free energy ( G), Helmholtz free energy ( A), entropy ( S), heat capacity at constant pressure ( Cp), heat capacity at constant volume ( Cv), coefficient of thermal expansion ( CTE), isothermal compressibility ( Ziso), velocity of sound ( VelS), partial derivative of P with T at constant V (d Pd T), partial derivative of T with V at constant P (d Td V), partial derivative of V with P at constant T (d Vd P), Joule-Thomson coefficient ( JTC), isothermal throttling coefficient ( IJTC), viscosity ( Vis), thermal conductivity ( ThrmCond), surface tension ( SurfTen), Prandtl number ( PrdNum) and dielectric constant ( DielCons) for the liquid and vapor phases of pure water. It also calculates T as a function of P (or P as a function of T) along the sublimation, saturation and critical isochor curves, depending on the values of P (or T). The SteamTables can be incorporated in a program in any computer language, which supports object link embedding (OLE) in the Windows environment. An application of SteamTables is illustrated in a program in Visual Basic 6.0 to tabulate the values of the thermodynamic properties of water and vapor. Similarly, four functions, Temperature(Press), Pressure(Temp), State(Temp, Press) and WtrStmTbls(Temp, Press, Nphs, Nprop), where Temp, Press, Nphs and Nprop are temperature, pressure, phase number and property number, respectively, are written in Visual Basic for Applications (VBA) to use the SteamTables in a workbook in MS-Excel.

  4. Toward a Scalable Visualization System for Network Traffic Monitoring

    NASA Astrophysics Data System (ADS)

    Malécot, Erwan Le; Kohara, Masayoshi; Hori, Yoshiaki; Sakurai, Kouichi

    With the multiplication of attacks against computer networks, system administrators are required to monitor carefully the traffic exchanged by the networks they manage. However, that monitoring task is increasingly laborious because of the augmentation of the amount of data to analyze. And that trend is going to intensify with the explosion of the number of devices connected to computer networks along with the global rise of the available network bandwidth. So system administrators now heavily rely on automated tools to assist them and simplify the analysis of the data. Yet, these tools provide limited support and, most of the time, require highly skilled operators. Recently, some research teams have started to study the application of visualization techniques to the analysis of network traffic data. We believe that this original approach can also allow system administrators to deal with the large amount of data they have to process. In this paper, we introduce a tool for network traffic monitoring using visualization techniques that we developed in order to assist the system administrators of our corporate network. We explain how we designed the tool and some of the choices we made regarding the visualization techniques to use. The resulting tool proposes two linked representations of the network traffic and activity, one in 2D and the other in 3D. As 2D and 3D visualization techniques have different assets, we resulted in combining them in our tool to take advantage of their complementarity. We finally tested our tool in order to evaluate the accuracy of our approach.

  5. Spatial issues in user interface design from a graphic design perspective

    NASA Technical Reports Server (NTRS)

    Marcus, Aaron

    1989-01-01

    The user interface of a computer system is a visual display that provides information about the status of operations on data within the computer and control options to the user that enable adjustments to these operations. From the very beginning of computer technology the user interface was a spatial display, although its spatial features were not necessarily complex or explicitly recognized by the users. All text and nonverbal signs appeared in a virtual space generally thought of as a single flat plane of symbols. Current technology of high performance workstations permits any element of the display to appear as dynamic, multicolor, 3-D signs in a virtual 3-D space. The complexity of appearance and the user's interaction with the display provide significant challenges to the graphic designer of current and future user interfaces. In particular, spatial depiction provides many opportunities for effective communication of objects, structures, processes, navigation, selection, and manipulation. Issues are presented that are relevant to the graphic designer seeking to optimize the user interface's spatial attributes for effective visual communication.

  6. Risk maps for navigation in liver surgery

    NASA Astrophysics Data System (ADS)

    Hansen, C.; Zidowitz, S.; Schenk, A.; Oldhafer, K.-J.; Lang, H.; Peitgen, H.-O.

    2010-02-01

    The optimal transfer of preoperative planning data and risk evaluations to the operative site is challenging. A common practice is to use preoperative 3D planning models as a printout or as a presentation on a display. One important aspect is that these models were not developed to provide information in complex workspaces like the operating room. Our aim is to reduce the visual complexity of 3D planning models by mapping surgically relevant information onto a risk map. Therefore, we present methods for the identification and classification of critical anatomical structures in the proximity of a preoperatively planned resection surface. Shadow-like distance indicators are introduced to encode the distance from the resection surface to these critical structures on the risk map. In addition, contour lines are used to accentuate shape and spatial depth. The resulting visualization is clear and intuitive, allowing for a fast mental mapping of the current resection surface to the risk map. Preliminary evaluations by liver surgeons indicate that damage to risk structures may be prevented and patient safety may be enhanced using the proposed methods.

  7. Integration of real-time 3D capture, reconstruction, and light-field display

    NASA Astrophysics Data System (ADS)

    Zhang, Zhaoxing; Geng, Zheng; Li, Tuotuo; Pei, Renjing; Liu, Yongchun; Zhang, Xiao

    2015-03-01

    Effective integration of 3D acquisition, reconstruction (modeling) and display technologies into a seamless systems provides augmented experience of visualizing and analyzing real objects and scenes with realistic 3D sensation. Applications can be found in medical imaging, gaming, virtual or augmented reality and hybrid simulations. Although 3D acquisition, reconstruction, and display technologies have gained significant momentum in recent years, there seems a lack of attention on synergistically combining these components into a "end-to-end" 3D visualization system. We designed, built and tested an integrated 3D visualization system that is able to capture in real-time 3D light-field images, perform 3D reconstruction to build 3D model of the objects, and display the 3D model on a large autostereoscopic screen. In this article, we will present our system architecture and component designs, hardware/software implementations, and experimental results. We will elaborate on our recent progress on sparse camera array light-field 3D acquisition, real-time dense 3D reconstruction, and autostereoscopic multi-view 3D display. A prototype is finally presented with test results to illustrate the effectiveness of our proposed integrated 3D visualization system.

  8. ONRASIA Scientific Information Bulletin, Volume 18 Number 1, January - March 1993,

    DTIC Science & Technology

    1993-03-01

    synthesized with half- mirrors to achieve this 3-D ers hope to be able to reflect time relationships in realization. This permits a 3-D visualization...field because the wires that stretch in all directions will of vision, so a mirror is placed in front of the become tangled. operator’s face at an...angle of 450 and the computer screen is prtjccted there. Thus the mirror hides the c. Joy Stick hands from view. "If we can recreate the trial-and-error

  9. In situ 3-D mapping of pore structures and hollow grains of interplanetary dust particles with phase contrast X-ray nanotomography

    NASA Astrophysics Data System (ADS)

    Hu, Z. W.; Winarski, R. P.

    2016-09-01

    Unlocking the 3-D structure and properties of intact chondritic porous interplanetary dust particles (IDPs) in nanoscale detail is challenging, which is also complicated by atmospheric entry heating, but is important for advancing our understanding of the formation and origins of IDPs and planetary bodies as well as dust and ice agglomeration in the outer protoplanetary disk. Here, we show that indigenous pores, pristine grains, and thermal alteration products throughout intact particles can be noninvasively visualized and distinguished morphologically and microstructurally in 3-D detail down to ~10 nm by exploiting phase contrast X-ray nanotomography. We have uncovered the surprisingly intricate, submicron, and nanoscale pore structures of a ~10-μm-long porous IDP, consisting of two types of voids that are interconnected in 3-D space. One is morphologically primitive and mostly submicron-sized intergranular voids that are ubiquitous; the other is morphologically advanced and well-defined intragranular nanoholes that run through the approximate centers of ~0.3 μm or lower submicron hollow grains. The distinct hollow grains exhibit complex 3-D morphologies but in 2-D projections resemble typical organic hollow globules observed by transmission electron microscopy. The particle, with its outer region characterized by rough vesicular structures due to thermal alteration, has turned out to be an inherently fragile and intricately submicron- and nanoporous aggregate of the sub-μm grains or grain clumps that are delicately bound together frequently with little grain-to-grain contact in 3-D space.

  10. Evaluation of a breast software model for 2D and 3D X-ray imaging studies of the breast.

    PubMed

    Baneva, Yanka; Bliznakova, Kristina; Cockmartin, Lesley; Marinov, Stoyko; Buliev, Ivan; Mettivier, Giovanni; Bosmans, Hilde; Russo, Paolo; Marshall, Nicholas; Bliznakov, Zhivko

    2017-09-01

    In X-ray imaging, test objects reproducing breast anatomy characteristics are realized to optimize issues such as image processing or reconstruction, lesion detection performance, image quality and radiation induced detriment. Recently, a physical phantom with a structured background has been introduced for both 2D mammography and breast tomosynthesis. A software version of this phantom and a few related versions are now available and a comparison between these 3D software phantoms and the physical phantom will be presented. The software breast phantom simulates a semi-cylindrical container filled with spherical beads of different diameters. Four computational breast phantoms were generated with a dedicated software application and for two of these, physical phantoms are also available and they are used for the side by side comparison. Planar projections in mammography and tomosynthesis were simulated under identical incident air kerma conditions. Tomosynthesis slices were reconstructed with an in-house developed reconstruction software. In addition to a visual comparison, parameters like fractal dimension, power law exponent β and second order statistics (skewness, kurtosis) of planar projections and tomosynthesis reconstructed images were compared. Visually, an excellent agreement between simulated and real planar and tomosynthesis images is observed. The comparison shows also an overall very good agreement between parameters evaluated from simulated and experimental images. The computational breast phantoms showed a close match with their physical versions. The detailed mathematical analysis of the images confirms the agreement between real and simulated 2D mammography and tomosynthesis images. The software phantom is ready for optimization purpose and extrapolation of the phantom to other breast imaging techniques. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  11. Synchrotron x-ray imaging of acoustic cavitation bubbles induced by acoustic excitation

    NASA Astrophysics Data System (ADS)

    Jung, Sung Yong; Park, Han Wook; Park, Sung Ho; Lee, Sang Joon

    2017-04-01

    The cavitation induced by acoustic excitation has been widely applied in various biomedical applications because cavitation bubbles can enhance the exchanges of mass and energy. In order to minimize the hazardous effects of the induced cavitation, it is essential to understand the spatial distribution of cavitation bubbles. The spatial distribution of cavitation bubbles visualized by the synchrotron x-ray imaging technique is compared to that obtained with a conventional x-ray tube. Cavitation bubbles with high density in the region close to the tip of the probe are visualized using the synchrotron x-ray imaging technique, however, the spatial distribution of cavitation bubbles in the whole ultrasound field is not detected. In this study, the effects of the ultrasound power of acoustic excitation and working medium on the shape and density of the induced cavitation bubbles are examined. As a result, the synchrotron x-ray imaging technique is useful for visualizing spatial distributions of cavitation bubbles, and it could be used for optimizing the operation conditions of acoustic cavitation.

  12. Three-dimensional gas exchange pathways in pome fruit characterized by synchrotron x-ray computed tomography.

    PubMed

    Verboven, Pieter; Kerckhofs, Greet; Mebatsion, Hibru Kelemu; Ho, Quang Tri; Temst, Kristiaan; Wevers, Martine; Cloetens, Peter; Nicolaï, Bart M

    2008-06-01

    Our understanding of the gas exchange mechanisms in plant organs critically depends on insights in the three-dimensional (3-D) structural arrangement of cells and voids. Using synchrotron radiation x-ray tomography, we obtained for the first time high-contrast 3-D absorption images of in vivo fruit tissues of high moisture content at 1.4-microm resolution and 3-D phase contrast images of cell assemblies at a resolution as low as 0.7 microm, enabling visualization of individual cell morphology, cell walls, and entire void networks that were previously unknown. Intercellular spaces were always clear of water. The apple (Malus domestica) cortex contains considerably larger parenchyma cells and voids than pear (Pyrus communis) parenchyma. Voids in apple often are larger than the surrounding cells and some cells are not connected to void spaces. The main voids in apple stretch hundreds of micrometers but are disconnected. Voids in pear cortex tissue are always smaller than parenchyma cells, but each cell is surrounded by a tight and continuous network of voids, except near brachyssclereid groups. Vascular and dermal tissues were also measured. The visualized network architecture was consistent over different picking dates and shelf life. The differences in void fraction (5.1% for pear cortex and 23.0% for apple cortex) and in gas network architecture helps explain the ability of tissues to facilitate or impede gas exchange. Structural changes and anisotropy of tissues may eventually lead to physiological disorders. A combined tomography and internal gas analysis during growth are needed to make progress on the understanding of void formation in fruit.

  13. Conventional plate fixation method versus pre-operative virtual simulation and three-dimensional printing-assisted contoured plate fixation method in the treatment of anterior pelvic ring fracture.

    PubMed

    Hung, Chun-Chi; Li, Yuan-Ta; Chou, Yu-Ching; Chen, Jia-En; Wu, Chia-Chun; Shen, Hsain-Chung; Yeh, Tsu-Te

    2018-05-03

    Treating pelvic fractures remains a challenging task for orthopaedic surgeons. We aimed to evaluate the feasibility, accuracy, and effectiveness of three-dimensional (3D) printing technology and computer-assisted virtual surgery for pre-operative planning in anterior ring fractures of the pelvis. We hypothesized that using 3D printing models would reduce operation time and significantly improve the surgical outcomes of pelvic fracture repair. We retrospectively reviewed the records of 30 patients with pelvic fractures treated by anterior pelvic fixation with locking plates (14 patients, conventional locking plate fixation; 16 patients, pre-operative virtual simulation with 3D, printing-assisted, pre-contoured, locking plate fixation). We compared operative time, instrumentation time, blood loss, and post-surgical residual displacements, as evaluated on X-ray films, among groups. Statistical analyses evaluated significant differences between the groups for each of these variables. The patients treated with the virtual simulation and 3D printing-assisted technique had significantly shorter internal fixation times, shorter surgery duration, and less blood loss (- 57 minutes, - 70 minutes, and - 274 ml, respectively; P < 0.05) than patients in the conventional surgery group. However, the post-operative radiological result was similar between groups (P > 0.05). The complication rate was less in the 3D printing group (1/16 patients) than in the conventional surgery group (3/14 patients). The 3D simulation and printing technique is an effective and reliable method for treating anterior pelvic ring fractures. With precise pre-operative planning and accurate execution of the procedures, this time-saving approach can provide a more personalized treatment plan, allowing for a safer orthopaedic surgery.

  14. Space Radiation Monitoring Center at SINP MSU

    NASA Astrophysics Data System (ADS)

    Kalegaev, Vladimir; Barinova, Wera; Barinov, Oleg; Bobrovnikov, Sergey; Dolenko, Sergey; Mukhametdinova, Ludmila; Myagkova, Irina; Nguen, Minh; Panasyuk, Mikhail; Shiroky, Vladimir; Shugay, Julia

    2015-04-01

    Data on energetic particle fluxes from Russian satellites have been collected in Space monitoring data center at Moscow State University in the near real-time mode. Web-portal http://smdc.sinp.msu.ru/ provides operational information on radiation state of the near-Earth space. Operational data are coming from space missions ELECTRO-L1, Meteor-M2. High-resolution data on energetic electron fluxes from MSU's satellite VERNOV with RELEC instrumentation on board are also available. Specific tools allow the visual representation of the satellite orbit in 3D space simultaneously with particle fluxes variations. Concurrent operational data coming from other spacecraft (ACE, GOES, SDO) and from the Earth's surface (geomagnetic indices) are used to represent geomagnetic and radiation state of near-Earth environment. Internet portal http://swx.sinp.msu.ru provides access to the actual data characterizing the level of solar activity, geomagnetic and radiation conditions in heliosphere and the Earth's magnetosphere in the real-time mode. Operational forecasting services automatically generate alerts on particle fluxes enhancements above the threshold values, both for SEP and relativistic electrons, using data from LEO and GEO orbits. The models of space environment working in autonomous mode are used to generalize the information obtained from different missions for the whole magnetosphere. On-line applications created on the base of these models provide short-term forecasting for SEP particles and relativistic electron fluxes at GEO and LEO, Dst and Kp indices online forecasting up to 1.5 hours ahead. Velocities of high-speed streams in solar wind on the Earth orbit are estimated with advance time of 3-4 days. Visualization system provides representation of experimental and modeling data in 2D and 3D.

  15. EXACT DOSE X-IRRADIATION OF VARIOUS REGIONS OF THE HEAD AND VISUAL SENSATIONS--X-RAY LOCATION METHOD OF STUDY OF THE REACTIVITY OF THE CENTRAL NERVOUS SYSTEM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gurtovoi, G.K.; Burdianskaya, E.O.

    1960-01-01

    The primary substrate excited by threshold doses of x radiation of the normal human eye causes perception of a light flash in the retinal region. The threshold dose for the retina is about 1 mr; the threshold absorbed dose is about 1 mrad. Persons with a removed eyeball, on irradiation of the operated region with a frontal x-ray beam, perceive a flash of light at definite doses of radiation. Six persons taking part in an experiment saw a flash at doses of 17 to 150 mr (different observers saw flash at different doses) and did not see flash at dosesmore » of 5 to 90 mr. The cause of x-ray phosphene on frontal irradiation of the region of the removed eye with threshold doses is neither the reactivity of the optic nerve stump, the reactivity of the parts of the brain irradiated, nor the sensitivity of the skin receptors. In the cases considered, the cause of x-ray phosphene was irradiation of the retina of the nomnal eye by scattered x rays. The averaged coefficient of scatter was about 2%. On irradiation of the occiptal regions of the brain in subjects with normal eyes at a dose of about 150 mr, one subject perceived a flash of light. In this case, the absorbed dose for the occipital regions of the brain was about 40 mrad. The reason for this phenomenon must be explored. Stimulation of the cerebral formations (after atrophic changes in the visual tract and cortex) by x radia tion with a dose of up to 3 r, did not cause visual sensations. With the disposition of the beam, the absorbed dose for the chiasma was about 1 rad and for the occipital regions about 0.2 rad. In the study of threshold visual sensation and their causes on x irradiation of various regions of the head, it is important to apply defined doses of radiation. Scatter of the x rays in the head must be taken into consideration. (auth)« less

  16. Visual completion from 2D cross-sections: Implications for visual theory and STEM education and practice.

    PubMed

    Gagnier, Kristin Michod; Shipley, Thomas F

    2016-01-01

    Accurately inferring three-dimensional (3D) structure from only a cross-section through that structure is not possible. However, many observers seem to be unaware of this fact. We present evidence for a 3D amodal completion process that may explain this phenomenon and provide new insights into how the perceptual system processes 3D structures. Across four experiments, observers viewed cross-sections of common objects and reported whether regions visible on the surface extended into the object. If they reported that the region extended, they were asked to indicate the orientation of extension or that the 3D shape was unknowable from the cross-section. Across Experiments 1, 2, and 3, participants frequently inferred 3D forms from surface views, showing a specific prior to report that regions in the cross-section extend straight back into the object, with little variance in orientation. In Experiment 3, we examined whether 3D visual inferences made from cross-sections are similar to other cases of amodal completion by examining how the inferences were influenced by observers' knowledge of the objects. Finally, in Experiment 4, we demonstrate that these systematic visual inferences are unlikely to result from demand characteristics or response biases. We argue that these 3D visual inferences have been largely unrecognized by the perception community, and have implications for models of 3D visual completion and science education.

  17. Towards a gestural 3D interaction for tangible and three-dimensional GIS visualizations

    NASA Astrophysics Data System (ADS)

    Partsinevelos, Panagiotis; Agadakos, Ioannis; Pattakos, Nikolas; Maragakis, Michail

    2014-05-01

    The last decade has been characterized by a significant increase of spatially dependent applications that require storage, visualization, analysis and exploration of geographic information. GIS analysis of spatiotemporal geographic data is operated by highly trained personnel under an abundance of software and tools, lacking interoperability and friendly user interaction. Towards this end, new forms of querying and interaction are emerging, including gestural interfaces. Three-dimensional GIS representations refer to either tangible surfaces or projected representations. Making a 3D tangible geographic representation touch-sensitive may be a convenient solution, but such an approach raises the cost significantly and complicates the hardware and processing required to combine touch-sensitive material (for pinpointing points) with deformable material (for displaying elevations). In this study, a novel interaction scheme upon a three dimensional visualization of GIS data is proposed. While gesture user interfaces are not yet fully acceptable due to inconsistencies and complexity, a non-tangible GIS system where 3D visualizations are projected, calls for interactions that are based on three-dimensional, non-contact and gestural procedures. Towards these objectives, we use the Microsoft Kinect II system which includes a time of flight camera, allowing for a robust and real time depth map generation, along with the capturing and translation of a variety of predefined gestures from different simultaneous users. By incorporating these features into our system architecture, we attempt to create a natural way for users to operate on GIS data. Apart from the conventional pan and zoom features, the key functions addressed for the 3-D user interface is the ability to pinpoint particular points, lines and areas of interest, such as destinations, waypoints, landmarks, closed areas, etc. The first results shown, concern a projected GIS representation where the user selects points and regions of interest while the GIS component responds accordingly by changing the scenario in a natural disaster application. Creating a 3D model representation of geospatial data provides a natural way for users to perceive and interact with space. To the best of our knowledge it is the first attempt to use Kinect II for GIS applications and generally virtual environments using novel Human Computer Interaction methods. Under a robust decision support system, the users are able to interact, combine and computationally analyze information in three dimensions using gestures. This study promotes geographic awareness and education and will prove beneficial for a wide range of geoscience applications including natural disaster and emergency management. Acknowledgements: This work is partially supported under the framework of the "Cooperation 2011" project ATLANTAS (11_SYN_6_1937) funded from the Operational Program "Competitiveness and Entrepreneurship" (co-funded by the European Regional Development Fund (ERDF)) and managed by the Greek General Secretariat for Research and Technology.

  18. Integrated Tsunami Database: simulation and identification of seismic tsunami sources, 3D visualization and post-disaster assessment on the shore

    NASA Astrophysics Data System (ADS)

    Krivorot'ko, Olga; Kabanikhin, Sergey; Marinin, Igor; Karas, Adel; Khidasheli, David

    2013-04-01

    One of the most important problems of tsunami investigation is the problem of seismic tsunami source reconstruction. Non-profit organization WAPMERR (http://wapmerr.org) has provided a historical database of alleged tsunami sources around the world that obtained with the help of information about seaquakes. WAPMERR also has a database of observations of the tsunami waves in coastal areas. The main idea of presentation consists of determining of the tsunami source parameters using seismic data and observations of the tsunami waves on the shore, and the expansion and refinement of the database of presupposed tsunami sources for operative and accurate prediction of hazards and assessment of risks and consequences. Also we present 3D visualization of real-time tsunami wave propagation and loss assessment, characterizing the nature of the building stock in cities at risk, and monitoring by satellite images using modern GIS technology ITRIS (Integrated Tsunami Research and Information System) developed by WAPMERR and Informap Ltd. The special scientific plug-in components are embedded in a specially developed GIS-type graphic shell for easy data retrieval, visualization and processing. The most suitable physical models related to simulation of tsunamis are based on shallow water equations. We consider the initial-boundary value problem in Ω := {(x,y) ?R2 : x ?(0,Lx ), y ?(0,Ly ), Lx,Ly > 0} for the well-known linear shallow water equations in the Cartesian coordinate system in terms of the liquid flow components in dimensional form Here ?(x,y,t) defines the free water surface vertical displacement, i.e. amplitude of a tsunami wave, q(x,y) is the initial amplitude of a tsunami wave. The lateral boundary is assumed to be a non-reflecting boundary of the domain, that is, it allows the free passage of the propagating waves. Assume that the free surface oscillation data at points (xm, ym) are given as a measured output data from tsunami records: fm(t) := ? (xm, ym,t), (xm,ym ) ?Ω, t ?(Tm1, Tm2), m = 1,2,...,M, M ?N (2) The problem of tsunami source reconstruction (inverse tsunami problem) consists of determining the unknown initial perturbation q(x,y) of the free surface defied in (1) from knowledge of the free surface oscillation data fm(t) given by (2). We present a numerical method to determine the tsunami source using measurements of the height of a passing tsunami wave. Proposed approach based on the weak solution theory for hyperbolic PDEs and adjoint problem method for minimization of the corresponding cost functional 2 J(q) = ?Aq - F? , F = (f1,...,fM ). (3) The adjoint problem is defined to obtain an explicit gradient formula for the cost functional (3). Different numerical algorithms (finite-difference approach and finite volume method) are proposed for the direct as well as adjoint problem. Conjugate gradient algorithm based on explicit gradient formula is used for numerical solution of the inverse problem (1)-(2). This work was partially supported by the Russian Foundation for Basic Research (project No. 12-01-00773) and by SB RAS interdisciplinary project 14 "Inverse Problems and Applications: Theory, Algorithms, Software".

  19. FPV: fast protein visualization using Java 3D.

    PubMed

    Can, Tolga; Wang, Yujun; Wang, Yuan-Fang; Su, Jianwen

    2003-05-22

    Many tools have been developed to visualize protein structures. Tools that have been based on Java 3D((TM)) are compatible among different systems and they can be run remotely through web browsers. However, using Java 3D for visualization has some performance issues with it. The primary concerns about molecular visualization tools based on Java 3D are in their being slow in terms of interaction speed and in their inability to load large molecules. This behavior is especially apparent when the number of atoms to be displayed is huge, or when several proteins are to be displayed simultaneously for comparison. In this paper we present techniques for organizing a Java 3D scene graph to tackle these problems. We have developed a protein visualization system based on Java 3D and these techniques. We demonstrate the effectiveness of the proposed method by comparing the visualization component of our system with two other Java 3D based molecular visualization tools. In particular, for van der Waals display mode, with the efficient organization of the scene graph, we could achieve up to eight times improvement in rendering speed and could load molecules three times as large as the previous systems could. EPV is freely available with source code at the following URL: http://www.cs.ucsb.edu/~tcan/fpv/

  20. A membrane assisted hybrid bioreactor for the post treatment of an anaerobic effluent from a fish canning factory.

    PubMed

    Oyanedel, V; Garrido, J M; Lema, J M; Méndez, R

    2003-01-01

    An innovative membrane assisted hybrid bioreactor was used to treat a mixture of two streams produced in a fish canning factory: a highly loaded stream that had previously been treated in an anaerobic contact reactor, and a second stream with a relatively low COD and N concentration. Experiments were carried out during two experimental stages: an aerobic stage, which is focused in the study on the aerobic oxidation of ammonia and COD and a nitrification-denitrification stage in which the study was mainly focused on the removal of nitrogen. Results of the aerobic period pointed out that it was feasible to achieve ammonia and COD removals of around 99% at OLR of 6.5 kg COD/m3 x d and NLR of 1.8 kg N-NH4+/m3 x d. Specific nitrifying activities of up to 0.78 g N-NH4+/g protein x d and 0.25 g N-NH4+/g VSS x d, were recorded for the attached and suspended biomass, respectively. Around 50-60% of the nitrifying capacity of the reactor was a result of the nitrifying capacity of the biofilm. During the nitrification-denitrification stage 76% of nitrogen removal was attained at an NLR of 0.8 kg N-NH4+/m3 x d. The biofilm nitrifying activity was not affected by the operating conditions of the system, as a result of the preferential consumption of COD by suspended biomass in the reactor. Thus, the combination of a hybrid system, with both suspended and attached biomass, and an ultrafiltration membrane module might be an alternative for treating wastewaters in compact biological systems. The intrinsic characteristics of the system made it feasible to operate at high OLR without problems related with the settling properties of the sludge or the drop in the nitrogen conversion. There were no solids in the effluent as a result of the use of the membrane filtration module.

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