Sample records for xc-224fe

  1. Status of ART-XC/SRG instrument

    NASA Astrophysics Data System (ADS)

    Pavlinsky, M.; Akimov, V.; Levin, V.; Krivchenko, A.; Rotin, A.; Kuznetsova, M.; Lapshov, I.; Tkachenko, A.; Semena, N.; Buntov, M.; Glushenko, A.; Arefiev, V.; Yaskovich, A.; Grebenev, S.; Sazonov, S.; Revnivtsev, M.; Lutovinov, A.; Molkov, S.; Krivonos, R.; Serbinov, D.; Kudelin, M.; Drozdova, T.; Voronkov, S.; Sunyaev, R.; Churazov, E.; Gilfanov, M.; Babyshkin, V.; Lomakin, I.; Menderov, A.; Gubarev, M.; Ramsey, B.; Kilaru, K.; O'Dell, S. L.; Kolodziejczak, J.; Elsner, R.; Zavlin, V.; Swartz, D.

    2016-07-01

    Spectrum Roentgen Gamma (SRG) is an X-ray astrophysical observatory, developed by Russia in collaboration with Germany. The mission will be launched in 2017 from Baikonur and placed in a 6-month-period halo orbit around L2. The scientific payload consists of two independent telescope arrays - a soft-x-ray survey instrument, eROSITA, being provided by Germany and a medium-x-ray-energy survey instrument ART-XC being developed by Russia. ART-XC will consist of seven independent, but co-aligned, telescope modules. The ART-XC flight mirror modules have been developed and fabricated at the NASA Marshall Space Flight Center (MSFC). Each mirror module will be aligned with a focal plane CdTe double-sided strip detector which will operate over the energy range of 6-30 keV, with an angular resolution of <1', a field of view of 34' and an expected energy resolution of about 12% at 14 keV. The current status of the ART-XC/SRG instrument is presented here.

  2. Status of ART-XC/SRG Instrument

    NASA Technical Reports Server (NTRS)

    Pavlinsky, M.; Akimov, V.; Levin, V.; Lapshov, I.; Tkachenko, A.; Semena, N.; Buntov, M.; Glushenko, A.; Arefiev, V.; Yaskovich, A.; hide

    2014-01-01

    Spectrum Roentgen Gamma (SRG) is an X-ray astrophysical observatory, developed by Russia in collaboration with Germany. The mission will be launched in March 2016 from Baikonur, by a Zenit rocket with a Fregat booster and placed in a 6-month-period halo orbit around L2. The scientific payload consists of two independent telescopes - a soft-x-ray survey instrument, eROSITA, being provided by Germany and a medium-x-ray-energy survey instrument ART-XC being developed by Russia. ART-XC will consist of seven independent, but co-aligned, telescope modules. The NASA Marshall Space Flight Center (MSFC) is fabricating the flight mirror modules for the ART-XC/SRG. Each mirror module will be aligned with a focal plane CdTe double-sided strip detectors which will operate over the energy range of 6-30 keV, with an angular resolution of less than 1', a field of view of approximately 34' and an expected energy resolution of about 10 percent at 14 keV.

  3. Calibration of the ART-XC mirror modules at MSFC

    NASA Astrophysics Data System (ADS)

    Krivonos, R.; Tkachenko, A.; Burenin, R.; Filippova, E.; Lapshov, I.; Mereminskiy, I.; Molkov, S.; Pavlinsky, M.; Sazonov, S.; Gubarev, M.; Kolodziejczak, J.; O'Dell, S. L.; Swartz, D.; Zavlin, Vyacheslav E.; Ramsey, B. D.

    2017-10-01

    The Astronomical Röntgen Telescope X-ray Concentrator (ART-XC) is a hard X-ray telescope with energy response up to 30 keV, to be launched on board the Spectrum Röntgen Gamma (SRG) spacecraft in 2018. ART-XC consists of seven identical co-aligned mirror modules. Each mirror assembly is coupled with a CdTe double-sided strip (DSS) focal-plane detector. Eight X-ray mirror modules (seven flight and one spare units) for ART-XC were developed and fabricated at the Marshall Space Flight Center (MSFC), NASA, USA. We present results of testing procedures performed with an X-ray beam facility at MSFC to calibrate the point spread function (PSF) of the mirror modules. The shape of the PSF was measured with a high-resolution CCD camera installed in the focal plane with defocusing of 7 mm, as required by the ART-XC design. For each module, we performed a parametrization of the PSF at various angular distances Θ. We used a King function to approximate the radial profile of the near on-axis PSF (Θ < 9 arcmin) and an ellipse fitting procedure to describe the morphology of the far off-axis angular response (9 < Θ < 24 arcmin). We found a good agreement between the seven ART-XC flight mirror modules at the level of 10%. The on-axis angular resolution of the ART-XC optics varies between 27 and 33 arcsec (half-power diameter), except for the spare module.

  4. On-ground calibration of the ART-XC/SRG mirror system and detector unit at IKI. Part I

    NASA Astrophysics Data System (ADS)

    Pavlinsky, M.; Tkachenko, A.; Levin, V.; Krivchenko, A.; Rotin, A.; Kuznetsova, M.; Lapshov, I.; Krivonos, R.; Semena, A.; Semena, N.; Serbinov, D.; Shtykovsky, A.; Yaskovich, A.; Oleinikov, V.; Glushenko, A.; Mereminskiy, I.; Molkov, S.; Sazonov, S.; Arefiev, V.

    2018-05-01

    From October 2016 to September 2017, we performed tests of the ART-XC /SRG spare mirror system and detector unit at the 60-m-long IKI X-ray test facility. We describe some technical features of this test facility. We also present a brief description of the ART-XC mirror system and focal detectors. The nominal focal length of the ART-XC optics is 2700 mm. The field of view is determined by the combination of the mirror system and the detector unit and is equal to ˜0.31 square degrees. The declared operating energy range is 5-30 keV. During the tests, we illuminated the detector with a 55Fe+241 Am calibration source and also with a quasi-parallel X-ray beam. The calibration source is integrated into the detector's collimator. The X-ray beam was generated by a set of Oxford Instruments X-ray tubes with Cr, Cu and Mo targets and an Amptek miniature X-ray tube (Mini-X) with Ag transmission target. The detector was exposed to the X-ray beam either directly or through the mirror system. We present the obtained results on the detector's energy resolution, the muon on-ground background level and the energy dependence of the W90 value. The accuracy of a mathematical model of the ART-XC mirror system, based on ray-tracing simulations, proves to be within 3.5% in the main energy range of 4-20 keV and 5.4% in the "hard" energy range of 20-40 keV.

  5. Infection of XC Cells by MLVs and Ebola Virus Is Endosome-Dependent but Acidification-Independent

    PubMed Central

    Kamiyama, Haruka; Kakoki, Katsura; Yoshii, Hiroaki; Iwao, Masatomo; Igawa, Tsukasa; Sakai, Hideki; Hayashi, Hideki; Matsuyama, Toshifumi; Yamamoto, Naoki; Kubo, Yoshinao

    2011-01-01

    Inhibitors of endosome acidification or cathepsin proteases attenuated infections mediated by envelope proteins of xenotropic murine leukemia virus-related virus (XMRV) and Ebola virus, as well as ecotropic, amphotropic, polytropic, and xenotropic murine leukemia viruses (MLVs), indicating that infections by these viruses occur through acidic endosomes and require cathepsin proteases in the susceptible cells such as TE671 cells. However, as previously shown, the endosome acidification inhibitors did not inhibit these viral infections in XC cells. It is generally accepted that the ecotropic MLV infection in XC cells occurs at the plasma membrane. Because cathepsin proteases are activated by low pH in acidic endosomes, the acidification inhibitors may inhibit the viral infections by suppressing cathepsin protease activation. The acidification inhibitors attenuated the activities of cathepsin proteases B and L in TE671 cells, but not in XC cells. Processing of cathepsin protease L was suppressed by the acidification inhibitor in NIH3T3 cells, but again not in XC cells. These results indicate that cathepsin proteases are activated without endosome acidification in XC cells. Treatment with an endocytosis inhibitor or knockdown of dynamin 2 expression by siRNAs suppressed MLV infections in all examined cells including XC cells. Furthermore, endosomal cathepsin proteases were required for these viral infections in XC cells as other susceptible cells. These results suggest that infections of XC cells by the MLVs and Ebola virus occur through endosomes and pH-independent cathepsin activation induces pH-independent infection in XC cells. PMID:22022555

  6. Deploying Darter A Cray XC30 System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fahey, Mark R; Budiardja, Reuben D; Crosby, Lonnie D

    TheUniversityofTennessee,KnoxvilleacquiredaCrayXC30 supercomputer, called Darter, with a peak performance of 248.9 Ter- aflops. Darter was deployed in late March of 2013 with a very aggressive production timeline - the system was deployed, accepted, and placed into production in only 2 weeks. The Spring Experiment for the Center for Analysis and Prediction of Storms (CAPS) largely drove the accelerated timeline, as the experiment was scheduled to start in mid-April. The Consortium for Advanced Simulation of Light Water Reactors (CASL) project also needed access and was able to meet their tight deadlines on the newly acquired XC30. Darter s accelerated deployment and op-more » erations schedule resulted in substantial scientific impacts within the re- search community as well as immediate real-world impacts such as early severe tornado warnings« less

  7. Development of Mirror Modules for the ART-XC Instrument

    NASA Technical Reports Server (NTRS)

    Gubarev, M.; Ramsey, B.; O'Dell, S. L.; Elsner, R.; Kilaru, K.; McCracken, J.; Pavlinsky, M.; Lapshov, I.

    2012-01-01

    The Marshall Space Flight Center (MSFC) is developing x-ray mirror modules for the ART -XC instrument on board the Spectrum-Roentgen-Gamma Mission under a Reimbursable Agreement between NASA and the Russian Space Research Institute (IKI.) ART-XC will consist of seven co-aligned x-ray mirror modules with seven corresponding CdTe focal plane detectors. Currently, four of the modules are being fabricated by the Marshall Space Flight Center (MSFC.) Each MSFC module provides an effective area of 65 cm2 at 8 keV, response out to 30 keV, and an angular resolution of 45 arcsec or better HPD. We will present a status of the ART x-ray module development at MSFC.

  8. Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision.

    PubMed

    Bentea, Eduard; Demuyser, Thomas; Van Liefferinge, Joeri; Albertini, Giulia; Deneyer, Lauren; Nys, Julie; Merckx, Ellen; Michotte, Yvette; Sato, Hideyo; Arckens, Lutgarde; Massie, Ann; Smolders, Ilse

    2015-06-03

    There is considerable preclinical and clinical evidence indicating that abnormal changes in glutamatergic signaling underlie the development of mood disorders. Astrocytic glutamate dysfunction, in particular, has been recently linked with the pathogenesis and treatment of mood disorders, including anxiety and depression. System xc- is a glial cystine/glutamate antiporter that is responsible for nonvesicular glutamate release in various regions of the brain. Although system xc- is involved in glutamate signal transduction, its possible role in mediating anxiety or depressive-like behaviors is currently unknown. In the present study, we phenotyped adult and aged system xc- deficient mice in a battery of tests for anxiety and depressive-like behavior (open field, light/dark test, elevated plus maze, novelty suppressed feeding, forced swim test, tail suspension test). Concomitantly, we evaluated the sensorimotor function of system xc- deficient mice, using motor and sensorimotor based tests (rotarod, adhesive removal test, nest building test). Finally, due to the presence and potential functional relevance of system xc- in the eye, we investigated the visual acuity of system xc- deficient mice (optomotor test). Our results indicate that loss of system xc- does not affect motor or sensorimotor function, in either adult or aged mice, in any of the paradigms investigated. Similarly, loss of system xc- does not affect basic visual acuity, in either adult or aged mice. On the other hand, in the open field and light/dark tests, and forced swim and tail suspension tests respectively, we could observe significant anxiolytic and antidepressive-like effects in system xc- deficient mice that in certain cases (light/dark, forced swim) were age-dependent. These findings indicate that, under physiological conditions, nonvesicular glutamate release via system xc- mediates aspects of higher brain function related to anxiety and depression, but does not influence sensorimotor function

  9. ART-XC: A Medium-energy X-ray Telescope System for the Spectrum-R-Gamma Mission

    NASA Technical Reports Server (NTRS)

    Arefiev, V.; Pavlinsky, M.; Lapshov, I.; Thachenko, A.; Sazonov, S.; Revnivtsev, M.; Semena, N.; Buntov,M.; Vikhlinin, A.; Gubarev, M.; hide

    2008-01-01

    The ART-XC instrument is an X-ray grazing-incidence telescope system in an ABRIXAS-type optical configuration optimized for the survey observational mode of the Spectrum-RG astrophysical mission which is scheduled to be launched in 2011. ART-XC has two units, each equipped with four identical X-ray multi-shell mirror modules. The optical axes of the individual mirror modules are not parallel but are separated by several degrees to permit the four modules to share a single CCD focal plane detector, 1/4 of the area each. The 450-micron-thick pnCCD (similar to the adjacent eROSITA telescope detector) will allow detection of X-ray photons up to 15 keV. The field of view of the individual mirror module is about 18 x 18 arcminutes(exp 2) and the sensitivity of the ART-XC system for 4 years of survey will be better than 10(exp -12) erg s(exp -1) cm(exp -2) over the 4-12 keV energy band. This will allow the ART-XC instrument to discover several thousand new AGNs.

  10. XMOS XC-2 Development Board for Mechanical Control and Data Collection

    NASA Technical Reports Server (NTRS)

    Jarnot, Robert F.; Bowden, William J.

    2011-01-01

    The scanning microwave limb sounder (SMLS) will use technological improvements in low-noise mixers to provide precise data on the Earth s atmospheric composition with high spatial resolution. This project focuses on the design and implementation of a realtime control system needed for airborne engineering tests of the SMLS. The system must coordinate the actuation of optical components using four motors with encoder readback, while collecting synchronized telemetric data from a GPS receiver and 3-axis gyrometric system. A graphical user interface for testing the control system was also designed using Python. Although the system could have been implemented with an FPGA(fieldprogrammable gate array)-based setup, a processor development kit manufactured by XMOS was chosen. The XMOS architecture allows parallel execution of multiple tasks on separate threads, making it ideal for this application. It is easily programmed using XC (a subset of C). The necessary communication interfaces were implemented in software, including Ethernet, with significant cost and time reduction compared to an FPGA-based approach. A simple approach to control the chopper, calibration mirror, and gimbal for the airborne SMLS was needed. The XMOS board allows for multiple threads and real-time data acquisition. The XC-2 development kit is an attractive choice for synchronized, real-time, event-driven applications. The XMOS is based on the transputer microprocessor architecture developed for parallel computing, which is being revamped in this new platform. The XMOS device has multiple cores capable of running parallel applications on separate threads. The threads communicate with each other via user-defined channels capable of transmitting data within the device. XMOS provides a C-based development environment using XC, which eliminates the need for custom tool kits associated with FPGA programming. The XC-2 has four cores and necessary hardware for Ethernet I/O.

  11. The ART-XC Instrument on Board the SRG Mission

    NASA Technical Reports Server (NTRS)

    Pavlinksy, M.; Akimov, V.; Levin, V.; Lapshov, I.; Tkachenko, A.; Semena, N.; Buntov, M.; Glushenko, A.; Arefiev, V.; Yaskovish, A.; hide

    2012-01-01

    Spectrum Roentgen Gamma (SRG) is an X-ray astrophysical observatory, developed by Russia in collaboration with Germany. The mission will be launched in 2014 from Baikonur, by a Zenit rocket with a Fregat booster and placed in a 6-month-period halo orbit around L2. The scientific payload consists of two independent telescopes . a soft-x-ray survey instrument, eROSITA, being provided by Germany and a medium-x-ray-energy survey instrument ART-XC being developed by Russia. ART-XC will consist of seven independent, but co-aligned, telescope modules with seven corresponding cadmium-telluride focal plane detectors. Each will operate over the approximate energy range of 6- 30 keV, with an angular resolution of <1 ', a field of view of 30 ' and an energy resolution about 10% at 14 keV. The NASA Marshall Space Flight Center (MSFC) will fabricate some of the mirror modules, to complement others fabricated by VNIIEF in Russia.

  12. XC-cell fusion induced by murine plasmocytoma cells. II. Cytological and ultrastructural study.

    PubMed

    Lemay, P; Torpier, G; Lefebvre, J C; Samaille, J

    1975-06-10

    The MF2 strain, a mouse myeloma derived cell line, was found to induce the mixed culture cytopathogenicity test when cocultured with XC cells. Only one MF2 cell was present per syncytium, as shown by autoradiography. Pretreatment of cells with inhibitors of DNA, RNA or protein synthesis suggested that a normal RNA synthesis was required to obtain optimal polykaryon growth. Immunoelectron microscopy using a syngenic mouse MF2 cell antiserum and peroxydase labeling revealed a complete mixing and redistribution of the respective plasma membrane sites of MF2 and XC cells on polykaryon surface.

  13. 49 CFR 571.224 - Standard No. 224; Rear impact protection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.224 Standard No. 224; Rear impact protection. S1. Scope. This... motor vehicle, as defined in 49 CFR 171.8, is certified to carry hazardous materials and has a rear...

  14. 49 CFR 571.224 - Standard No. 224; Rear impact protection.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.224 Standard No. 224; Rear impact protection. S1. Scope. This... motor vehicle, as defined in 49 CFR 171.8, is certified to carry hazardous materials and has a rear...

  15. 49 CFR 571.224 - Standard No. 224; Rear impact protection.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.224 Standard No. 224; Rear impact protection. S1. Scope. This... motor vehicle, as defined in 49 CFR 171.8, is certified to carry hazardous materials and has a rear...

  16. Preparation of the vulcan XC-72R-supported Pt nanoparticles for the hydrogen evolution reaction in PEM water electrolysers

    NASA Astrophysics Data System (ADS)

    Du Nguyen, Huy; Thuy Luyen Nguyen, T.; Nguyen, Khac Manh; Ha, Thuc Huy; Hien Nguyen, Quoc

    2015-01-01

    Pt nanoparticles on vulcan XC-72R support (Pt/vulcan XC-72R) were prepared by the impregnation-reduction method. The Pt content, the morphological properties and the electrochemical catalysis of the Pt/vulcan XC 72R materials have been investigated by ICP-OES analysis, FESEM, TEM, and cyclic voltammetry. These materials were then used as catalyst for hydrogen evolution reaction at the cathode of proton exchange membrane (PEM) water electrolysers. The best catalyst was Pt/vulcan XC-72R prepared by the impregnation-reduction method which is conducted in two reducing steps with the reductants of sodium borohydride and ethylene glycol, respectively. The current density of PEM water electrolysers reached 1.0 A cm-2 when applying a voltage of 2.0 V at 25 °C.

  17. ART-XC/SRG: joint calibration of mirror modules and x-ray detectors

    NASA Astrophysics Data System (ADS)

    Tkachenko, A.; Pavlinsky, M.; Levin, V.; Akimov, V.; Krivchenko, A.; Rotin, A.; Kuznetsova, M.; Lapshov, I.; Yaskovich, A.; Oleinikov, V.; Gubarev, M.; Ramsey, B.

    2017-08-01

    The Astronomical Roentgen Telescope - X-ray Concentrator (ART-XC) is a hard x-ray instrument with energy response 6-30 keV that will to be launched on board of the Spectrum Roentgen Gamma (SRG) Mission. ART-XC consists of seven co-aligned mirror modules coupled with seven focal plane CdTe double-sided strip detectors. The mirror modules had been fabricated and calibrated at the NASA Marshall Space Flight Center (MSFC). The Russian Space Research Institute (IKI) has developed and tested the X-ray detectors. The joint x-ray calibration of the mirror modules and focal plane detectors was carried out at the IKI test facility. Details of the calibration procedure and an overview of the results are presented here.

  18. 40 CFR 415.224 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 30 2012-07-01 2012-07-01 false [Reserved] 415.224 Section 415.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE CATEGORY Titanium Dioxide Production Subcategory § 415.224...

  19. 40 CFR 415.224 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 30 2013-07-01 2012-07-01 true [Reserved] 415.224 Section 415.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE CATEGORY Titanium Dioxide Production Subcategory § 415.224...

  20. 40 CFR 415.224 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 29 2011-07-01 2009-07-01 true [Reserved] 415.224 Section 415.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE CATEGORY Titanium Dioxide Production Subcategory § 415.224...

  1. 40 CFR 415.224 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 415.224 Section 415.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE CATEGORY Titanium Dioxide Production Subcategory § 415.224...

  2. 40 CFR 415.224 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 29 2014-07-01 2012-07-01 true [Reserved] 415.224 Section 415.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE CATEGORY Titanium Dioxide Production Subcategory § 415.224...

  3. 49 CFR 224.7 - Waivers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Waivers. 224.7 Section 224.7 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.7 Waivers. (a) Any person subject to...

  4. 49 CFR 224.3 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Applicability. 224.3 Section 224.3 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.3 Applicability. This part applies to...

  5. High magnetization Fe-Co and Fe-Ni submicron and nanosize particles by thermal decomposition and hydrogen reduction

    NASA Astrophysics Data System (ADS)

    Cui, B. Z.; Marinescu, M.; Liu, J. F.

    2014-05-01

    This paper reports morphology, structure, and magnetic properties of air-stable soft magnetic FexCo100-x (x = 65, 50, and 34) and Fe50Ni50 (at. %) submicron and nanosize particles fabricated by template-free thermal decomposition of nitrates of Fe, Co, and Ni and subsequent hydrogen reduction. The particle compositions were tuned by modification of the precursor solution concentrations. The as-synthesized Fe-Co and Fe50Ni50 particles have body centered cubic and face centered cubic poly-nanocrystalline structures, respectively. The Fe-Co and Fe50Ni50 particles have particle sizes in the range of 28-200 nm and 70-480 nm, and average grain sizes of 16-29 nm and 20-24 nm, respectively. The particle and grain sizes were controlled by tuning particle composition, and the temperature and time of hydrogen reduction. Saturation magnetization Ms as high as 207-224 emu/g and intrinsic coercivity Hci of 59-228 Oe were obtained in the Fe-Co particles reduced at 550 °C for 90 min. Of special note, the Ms of 224 emu/g (˜2.3 T) obtained in the Fe65Co35 particles is among the highest values for Fe-Co particles reported so far. Ms of 135-137 emu/g and Hci of 59-111 Oe were obtained in the Fe50Ni50 particles reduced at 500 or 550 °C for 20 min.

  6. 40 CFR 224.2 - Reports.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Reports. 224.2 Section 224.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING RECORDS AND REPORTS REQUIRED OF OCEAN DUMPING PERMITTEES UNDER SECTION 102 OF THE ACT § 224.2 Reports. (a) Periodic reports...

  7. 40 CFR 224.2 - Reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Reports. 224.2 Section 224.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING RECORDS AND REPORTS REQUIRED OF OCEAN DUMPING PERMITTEES UNDER SECTION 102 OF THE ACT § 224.2 Reports. (a) Periodic reports...

  8. Synthetic, Infrared, 1H and 13C NMR Spectral Studies on N-(2-/3-Substituted Phenyl)-4-Substituted Benzenesulphonamides, 4-X'C6H4SO2NH(2-/3-XC6H4), where X' = H, CH3, C2H5, F, Cl or Br, and X = CH3 or Cl

    NASA Astrophysics Data System (ADS)

    Gowda, B. Thimme; Shetty, Mahesha; Jayalakshmi, K. L.

    2005-02-01

    Twenty three N-(2-/3-substituted phenyl)-4-substituted benzenesulphonamides of the general formula, 4-X'C6H4SO2NH(2-/3-XC6H4), where X' = H, CH3, C2H5, F, Cl or Br and X = CH3 or Cl have been prepared and characterized, and their infrared spectra in the solid state, 1H and 13C NMR spectra in solution were studied. The N-H stretching vibrations, νN-H, absorb in the range 3285 - 3199 cm-1, while the asymmetric and symmetric SO2 vibrations vary in the ranges 1376 - 1309 cm-1 and 1177 - 1148 cm-1, respectively. The S-N and C-N stretching vibrations absorb in the ranges 945 - 893 cm-1 and 1304 - 1168 cm-1, respectively. The compounds do not exhibit particular trends in the variation of these frequencies on substitution either at ortho or meta positions with either a methyl group or Cl. The observed 1H and 13C chemical shifts of are assigned to protons and carbons of the two benzene rings. Incremental shifts of the ring protons and carbons due to -SO2NH(2-/3-XC6H4) groups in C6H5SO2NH(2-/3-XC6H4), and 4- X'C6H4SO2- and 4-X'C6H4SO2NH- groups in 4-X'C6H4SO2NH(C6H5) are computed and employed to calculate the chemical shifts of the ring protons and carbons in the substituted compounds, 4-X'C6H4SO2NH(2-/3-XC6H4). The computed values agree well with the observed chemical shifts.

  9. 49 CFR 224.11 - Penalties.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Penalties. 224.11 Section 224.11 Transportation... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.11 Penalties. (a) Any person... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

  10. 49 CFR 224.11 - Penalties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Penalties. 224.11 Section 224.11 Transportation... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.11 Penalties. (a) Any person... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

  11. 49 CFR 224.11 - Penalties.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Penalties. 224.11 Section 224.11 Transportation... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.11 Penalties. (a) Any person... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

  12. 49 CFR 224.11 - Penalties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Penalties. 224.11 Section 224.11 Transportation... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.11 Penalties. (a) Any person... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

  13. 49 CFR 224.11 - Penalties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Penalties. 224.11 Section 224.11 Transportation... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.11 Penalties. (a) Any person... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

  14. Development of Mirror Modules for the ART-XC Instrument aboard the Spectrum-Roentgen-Gamma Mission

    NASA Technical Reports Server (NTRS)

    Gubarev, Mikhail V.; Ramsey, Brian; O'Dell, Stephen L.; Elsner, Ronald F.; Kilaru, Kiranmayee; Atkins, Carolyn; Pavlinskiy, Mikhail N.; Tkachenko, Alexey V.; Lapshov, Igor Y.

    2013-01-01

    The Marshall Space Flight Center (MSFC) is developing x-ray mirror modules for the Astronomical Roengen Telescope- X-ray Concentrator (ART-XC) instrument on board the Spectrum-Roentgen-Gamma Mission. ART-XC will consist of seven co-aligned x-ray mirror modules with seven corresponding CdTe focal plane detectors. Each module provides an effective area of 65 sq cm at 8 keV, response out to 30 keV, and an angular resolution of 45 arcsec or better HPD. We will present a status of the ART x-ray module development at MSFC.

  15. A leap forward with UTK s Cray XC30

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fahey, Mark R

    2014-01-01

    This paper shows a significant productivity leap for several science groups and the accomplishments they have made to date on Darter - a Cray XC30 at the University of Tennessee Knoxville. The increased productivity is due to faster processors and interconnect combined in a new generation from Cray, and yet it still has a very similar programming environment as compared to previous generations of Cray machines that makes porting easy.

  16. Uric acid-derived Fe3C-containing mesoporous Fe/N/C composite with high activity for oxygen reduction reaction in alkaline medium

    NASA Astrophysics Data System (ADS)

    Ma, Jun; Xiao, Dejian; Chen, Chang Li; Luo, Qiaomei; Yu, Yue; Zhou, Junhao; Guo, Changding; Li, Kai; Ma, Jie; Zheng, Lirong; Zuo, Xia

    2018-02-01

    In this work, a category of Fe3C-containing Fe/N/C mesoporous material has been fabricated by carbonizing the mixture of uric acid, Iron (Ⅲ) chloride anhydrous and carbon support (XC-72) under different pyrolysis temperature. Of all these samples, pyrolysis temperature (800 °C) becomes the most crucial factor in forming Fe3C active sites which synergizes with high content of graphitic N to catalyze oxygen reduction reaction (ORR). X-ray absorption fine structure spectroscopy (XAFS) is used to exhibit that the space structure around Fe atoms in the catalyst. This kind of catalyst possesses comparable ORR properties with commercial 20% Pt/C (onset potential is 0 V vs. Ag/AgCl in 0.1 M KOH), the average transfer electron number is 3.84 reflecting the 4-electron process. Moreover, superior stability and methanol tolerance deserve to be mentioned.

  17. Xc- inhibitor sulfasalazine sensitizes colorectal cancer to cisplatin by a GSH-dependent mechanism.

    PubMed

    Ma, Ming-zhe; Chen, Gang; Wang, Peng; Lu, Wen-hua; Zhu, Chao-feng; Song, Ming; Yang, Jing; Wen, Shijun; Xu, Rui-hua; Hu, Yumin; Huang, Peng

    2015-11-01

    Sulfasalazine (SSZ) is an anti-inflammatory drug that has been demonstrated to induce apoptosis and tumor regression through inhibition of plasma membrane cystine transporter xc(-). Cysteine is a rate-limiting precursor for intracellular glutathione (GSH) synthesis, which is vital for compound detoxification and maintaining redox balance. Platinum-based chemotherapy is an important regimen used in clinics for various cancers including colorectal cancer (CRC). We hypothesized that targeting xc(-) transporter by SSZ may annihilate cellular detoxification through interruption of GSH synthesis and may enhance the anti-cancer activity of cisplatin (CDDP) by increasing drug transport. In the present study, we revealed that xCT, the active subunit of xc(-), is highly expressed in CRC cell lines and human colorectal carcinoma tissues compared with their normal counterparts. SSZ effectively depleted cellular GSH, leading to significant accumulation of reactive oxygen species and growth inhibition in CRC cells. In contrast, the normal epithelial cells of colon origin were less sensitive to SSZ, showing a moderate ROS elevation. Importantly, SSZ effectively enhanced the intracellular platinum level and cytotoxicity of CDDP in CRC cells. The synergistic effect of SSZ and CDDP was reversed by antioxidant N-acetyl-L-cysteine (NAC). Together, these results suggest that SSZ, a relatively non-toxic drug that targets cystine transporter, may, in combination with CDDP, have effective therapy for colorectal cancer. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  18. Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum.

    PubMed

    Burdo, Joseph; Dargusch, Richard; Schubert, David

    2006-05-01

    System x(c)(-), one of the main transporters responsible for central nervous system cystine transport, is comprised of two subunits, xCT and 4F2hc. The transport of cystine into cells is rate limiting for glutathione synthesis, the major antioxidant and redox cofactor in the brain. Alterations in glutathione status are prevalent in numerous neurodegenerative diseases, emphasizing the importance of proper cystine homeostasis. However, the distribution of xCT and 4F2hc within the brain and other areas has not been described. Using specific antibodies, both xCT and 4F2hc were localized predominantly to neurons in the mouse and human brain, but some glial cells were labeled as well. Border areas between the brain proper and periphery including the vascular endothelial cells, ependymal cells, choroid plexus, and leptomeninges were also highly positive for the system x(c)(-) components. xCT and 4F2hc are also present at the brush border membranes in the kidney and duodenum. These results indicate that system x(c)(-) is likely to play a role in cellular health throughout many areas of the brain as well as other organs by maintaining intracellular cystine levels, thereby resulting in low levels of oxidative stress.

  19. Prospective and Retrospective Evaluation of the Performance of the FDA-Approved Cepheid Xpert Flu/RSV XC Assay.

    PubMed

    Arbefeville, Sophie; Thonen-Kerr, Elizabeth; Ferrieri, Patricia

    2017-11-08

    Rapid and accurate detection of respiratory viruses is important in patient care and in guiding therapy and infection prevention policy. Rapid viral antigen assays are simple to perform and provide results within 15 to 30 minutes but are limited by their modest-to-moderate sensitivity. Molecular assays are more sensitive and specific but require more technical time and expertise and are more expensive. We verified the performance of the Xpert Flu/RSV XC assay prospectively, using patient respiratory samples from the 2014-2015 respiratory season, and, retrospectively, with frozen patient samples from the previous respiratory season. A total of 60 specimens were assayed on the Xpert Flu/RSV XC assay and by the GenMark Diagnostics eSensor Respiratory Viral Panel. The sensitivity of the Xpert Flu/RSV XC for Flu A was 100% (23/23), for Flu B, 80% (8/10), and for respiratory syncytial virus (RSV), 94.1% (16/17), compared to the reference assay (GenMark). The specificity was 100%. Eight specimens were positive for viruses other than Flu A/B or RSV, and this did not interfere with detection of targets in the Xpert assay. We demonstrated that the performance of the Xpert Flu/RSV XC was comparable to the more comprehensive molecular respiratory assay. © American Society for Clinical Pathology, 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. 49 CFR 195.224 - Welding: Weather.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Welding: Weather. 195.224 Section 195.224 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.224 Welding: Weather. Welding must be protected from weather conditions that...

  1. 49 CFR 195.224 - Welding: Weather.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Welding: Weather. 195.224 Section 195.224 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.224 Welding: Weather. Welding must be protected from weather conditions that...

  2. 49 CFR 195.224 - Welding: Weather.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Welding: Weather. 195.224 Section 195.224 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.224 Welding: Weather. Welding must be protected from weather conditions that...

  3. 49 CFR 195.224 - Welding: Weather.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Welding: Weather. 195.224 Section 195.224 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.224 Welding: Weather. Welding must be protected from weather conditions that...

  4. 49 CFR 195.224 - Welding: Weather.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Welding: Weather. 195.224 Section 195.224 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.224 Welding: Weather. Welding must be protected from weather conditions that...

  5. 42 CFR 93.224 - Research record.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Research record. 93.224 Section 93.224 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.224 Research record. Research record means the record of data or results that...

  6. 42 CFR 93.224 - Research record.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Research record. 93.224 Section 93.224 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.224 Research record. Research record means the record of data or results that...

  7. 42 CFR 93.224 - Research record.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Research record. 93.224 Section 93.224 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.224 Research record. Research record means the record of data or results that...

  8. 42 CFR 93.224 - Research record.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Research record. 93.224 Section 93.224 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.224 Research record. Research record means the record of data or results that...

  9. 42 CFR 93.224 - Research record.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Research record. 93.224 Section 93.224 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.224 Research record. Research record means the record of data or results that...

  10. Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model.

    PubMed

    Demuyser, Thomas; Deneyer, Lauren; Bentea, Eduard; Albertini, Giulia; Femenia, Teresa; Walrave, Laura; Sato, Hideyo; Danbolt, Niels C; De Bundel, Dimitri; Michotte, Alex; Lindskog, Maria; Massie, Ann; Smolders, Ilse

    2017-09-27

    The cystine/glutamate antiporter (system xc-) is believed to contribute to nonvesicular glutamate release from glial cells in various brain areas. Although recent investigations implicate system xc- in mood disorders, unambiguous evidence has not yet been established. Therefore, we evaluated the possible role of system xc- in the depressive state. We conducted a protein expression analysis of the specific subunit of system xc- (xCT) in brain regions of the corticosterone mouse model, Flinders Sensitive Line rat model and post-mortem tissue of depressed patients. We next subjected system xc- deficient mice to the corticosterone model and analysed their behaviour in several tests. Lastly, we subjected additional cohorts of xCT-deficient and wild-type mice to N-acetylcysteine treatment to unveil whether the previously reported antidepressant-like effects are dependent upon system xc-. We did not detect any changes in xCT expression levels in the animal models or patients compared to proper controls. Furthermore, loss of system xc- had no effect on depression- and anxiety-like behaviour. Finally, the antidepressant-like effects of N-acetylcysteine are not mediated via system xc-. xCT protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model.

  11. 9 CFR 354.224 - Water supply.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Water supply. 354.224 Section 354.224....224 Water supply. The water supply shall be ample, clean, and potable with adequate facilities for its distribution in the plant and its protection against contamination and pollution. (a) Hot water at a...

  12. 40 CFR 52.224 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false General requirements. 52.224 Section 52.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.224 General requirements. (a) The requirements of § 51.116(c) of this chapter are...

  13. 40 CFR 52.224 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false General requirements. 52.224 Section 52.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.224 General requirements. (a) The requirements of § 51.116(c) of this chapter are...

  14. 40 CFR 52.224 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false General requirements. 52.224 Section 52.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.224 General requirements. (a) The requirements of § 51.116(c) of this chapter are...

  15. 40 CFR 52.224 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false General requirements. 52.224 Section 52.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.224 General requirements. (a) The requirements of § 51.116(c) of this chapter are...

  16. 40 CFR 52.224 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false General requirements. 52.224 Section 52.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.224 General requirements. (a) The requirements of § 51.116(c) of this chapter are...

  17. 9 CFR 354.224 - Water supply.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Water supply. 354.224 Section 354.224....224 Water supply. The water supply shall be ample, clean, and potable with adequate facilities for its distribution in the plant and its protection against contamination and pollution. (a) Hot water at a...

  18. 9 CFR 354.224 - Water supply.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Water supply. 354.224 Section 354.224....224 Water supply. The water supply shall be ample, clean, and potable with adequate facilities for its distribution in the plant and its protection against contamination and pollution. (a) Hot water at a...

  19. 9 CFR 354.224 - Water supply.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Water supply. 354.224 Section 354.224....224 Water supply. The water supply shall be ample, clean, and potable with adequate facilities for its distribution in the plant and its protection against contamination and pollution. (a) Hot water at a...

  20. 9 CFR 354.224 - Water supply.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Water supply. 354.224 Section 354.224....224 Water supply. The water supply shall be ample, clean, and potable with adequate facilities for its distribution in the plant and its protection against contamination and pollution. (a) Hot water at a...

  1. 42 CFR 438.224 - Confidentiality.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Confidentiality. 438.224 Section 438.224 Public...) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE Quality Assessment and Performance Improvement Structure and... enrollment information that identifies a particular enrollee, each MCO, PIHP, and PAHP uses and discloses...

  2. 42 CFR 438.224 - Confidentiality.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Confidentiality. 438.224 Section 438.224 Public...) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE Quality Assessment and Performance Improvement Structure and... enrollment information that identifies a particular enrollee, each MCO, PIHP, and PAHP uses and discloses...

  3. 42 CFR 438.224 - Confidentiality.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Confidentiality. 438.224 Section 438.224 Public...) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE Quality Assessment and Performance Improvement Structure and... enrollment information that identifies a particular enrollee, each MCO, PIHP, and PAHP uses and discloses...

  4. 50 CFR 217.224 - Mitigation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 10 2014-10-01 2014-10-01 false Mitigation. 217.224 Section 217.224 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKE OF MARINE MAMMALS INCIDENTAL TO...

  5. 49 CFR 224.15 - Special approval procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Special approval procedures. 224.15 Section 224.15 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.15 Special approval...

  6. 22 CFR 224.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... limited to any advantage, preference, privilege, license, permit, favorable decision, ruling, status, or... United States Government. Individual means a natural person. Initial decision means the written decision of the ALJ required by § 224.10 or § 224.37, and includes a revised initial decision issued following...

  7. 22 CFR 224.14 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Separation of functions. 224.14 Section 224.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.14 Separation of functions. (a) The investigating official, the reviewing official, and any...

  8. 22 CFR 224.21 - Discovery.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Discovery. 224.21 Section 224.21 Foreign....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... parties, discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery...

  9. 22 CFR 224.21 - Discovery.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Discovery. 224.21 Section 224.21 Foreign....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... parties, discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery...

  10. 22 CFR 224.21 - Discovery.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Discovery. 224.21 Section 224.21 Foreign....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... parties, discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery...

  11. 22 CFR 224.21 - Discovery.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Discovery. 224.21 Section 224.21 Foreign....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... parties, discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery...

  12. 22 CFR 224.21 - Discovery.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discovery. 224.21 Section 224.21 Foreign....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... parties, discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery...

  13. 37 CFR 42.224 - Discovery.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Discovery. 42.224 Section 42... Post-Grant Review § 42.224 Discovery. Notwithstanding the discovery provisions of subpart A: (a) Requests for additional discovery may be granted upon a showing of good cause as to why the discovery is...

  14. 37 CFR 42.224 - Discovery.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Discovery. 42.224 Section 42... Post-Grant Review § 42.224 Discovery. Notwithstanding the discovery provisions of subpart A: (a) Requests for additional discovery may be granted upon a showing of good cause as to why the discovery is...

  15. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Post-hearing briefs. 224.36 Section 224.36...

  16. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Post-hearing briefs. 224.36 Section 224.36...

  17. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Post-hearing briefs. 224.36 Section 224.36...

  18. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Post-hearing briefs. 224.36 Section 224.36...

  19. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Post-hearing briefs. 224.36 Section 224.36...

  20. 49 CFR 224.103 - Characteristics of retroreflective sheeting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Characteristics of retroreflective sheeting. 224.103 Section 224.103 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL... Application, Inspection, and Maintenance of Retroreflective Material § 224.103 Characteristics of...

  1. 49 CFR 224.103 - Characteristics of retroreflective sheeting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Characteristics of retroreflective sheeting. 224.103 Section 224.103 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL... Application, Inspection, and Maintenance of Retroreflective Material § 224.103 Characteristics of...

  2. 40 CFR 61.224 - Recordkeeping requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Recordkeeping requirements. 61.224 Section 61.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  3. 40 CFR 61.224 - Recordkeeping requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Recordkeeping requirements. 61.224 Section 61.224 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  4. Exploiting Thread Parallelism for Ocean Modeling on Cray XC Supercomputers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarje, Abhinav; Jacobsen, Douglas W.; Williams, Samuel W.

    The incorporation of increasing core counts in modern processors used to build state-of-the-art supercomputers is driving application development towards exploitation of thread parallelism, in addition to distributed memory parallelism, with the goal of delivering efficient high-performance codes. In this work we describe the exploitation of threading and our experiences with it with respect to a real-world ocean modeling application code, MPAS-Ocean. We present detailed performance analysis and comparisons of various approaches and configurations for threading on the Cray XC series supercomputers.

  5. 49 CFR 224.105 - Sheeting dimensions and quantity.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Sheeting dimensions and quantity. 224.105 Section 224.105 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD..., Inspection, and Maintenance of Retroreflective Material § 224.105 Sheeting dimensions and quantity...

  6. 49 CFR 224.105 - Sheeting dimensions and quantity.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Sheeting dimensions and quantity. 224.105 Section 224.105 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD..., Inspection, and Maintenance of Retroreflective Material § 224.105 Sheeting dimensions and quantity...

  7. 49 CFR 224.105 - Sheeting dimensions and quantity.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Sheeting dimensions and quantity. 224.105 Section 224.105 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD..., Inspection, and Maintenance of Retroreflective Material § 224.105 Sheeting dimensions and quantity...

  8. 49 CFR 224.105 - Sheeting dimensions and quantity.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Sheeting dimensions and quantity. 224.105 Section 224.105 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD..., Inspection, and Maintenance of Retroreflective Material § 224.105 Sheeting dimensions and quantity...

  9. 49 CFR 224.105 - Sheeting dimensions and quantity.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Sheeting dimensions and quantity. 224.105 Section 224.105 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD..., Inspection, and Maintenance of Retroreflective Material § 224.105 Sheeting dimensions and quantity...

  10. 49 CFR 224.106 - Location of retroreflective sheeting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Location of retroreflective sheeting. 224.106 Section 224.106 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD..., Inspection, and Maintenance of Retroreflective Material § 224.106 Location of retroreflective sheeting. (a...

  11. The energy gap in a-Si 1 - xC g: H alloys

    NASA Astrophysics Data System (ADS)

    Valladares, Ariel A.; Valladares, Alexander; Enrique Sansores, L.; Nelis, Mary Ann Me

    1997-02-01

    The electronic structure of amorphous tetrahedral clusters of the type a-Si 1 - xC g: H are studied using the pseudopotential SCF Hartree-Fock approximation. The reduced energy gap isgiven by Egr( x) - 1 + 0.84 x for x ⩽ 0.5, whereas experimentally Egr( x) = 1 + 0.96 x. For x ⩾ 0.5 the dip in the gap value reported experimentally is verified.

  12. 49 CFR 384.224 - Noncommercial motor vehicle violations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Noncommercial motor vehicle violations. 384.224 Section 384.224 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... § 384.224 Noncommercial motor vehicle violations. The State must have and enforce laws and/or...

  13. 49 CFR 384.224 - Noncommercial motor vehicle violations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Noncommercial motor vehicle violations. 384.224 Section 384.224 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... § 384.224 Noncommercial motor vehicle violations. The State must have and enforce laws and/or...

  14. Number of Blades-up Runs Using JetStream XC Atherectomy for Optimal Tissue Debulking in Patients with Femoropopliteal Artery In-Stent Restenosis.

    PubMed

    Shammas, Nicolas W; Shammas, Gail A; Aasen, Nicole; Jarvis, Gary

    2015-12-01

    Rotational atherectomy with the use of the JetStream XC device is indicated for treatment of infrainguinal arterial obstructive disease. The number of blades-up (BU) runs needed for optimal tissue debulking in femoropopliteal in-stent restenosis (ISR) is unknown. In the present series, 6 patients (15 lesions) were treated for femoropopliteal ISR with the JetStream XC device. Minimal luminal diameter or percent stenosis improved significantly from baseline after 2 BU runs, but no further gain was seen between 2 and 4 BU runs (P > .05). However, adjunctive balloon angioplasty reduced percent stenosis significantly following BU runs. In conclusion, the JetStream XC device achieved optimal acute angiographic results in treating femoropopliteal ISR following 2 BU runs and adjunctive balloon angioplasty. Copyright © 2015 SIR. Published by Elsevier Inc. All rights reserved.

  15. Development of Mirror Modules for the ART-XC Instrument aboard the Spectrum-Roentgen-Gamma Mission

    NASA Technical Reports Server (NTRS)

    Gubarev, M.; Ramsey, B.; O'Dell, S. L.; Elsner, R.; Kilaru, K.; McCracken, J.; Atkins, C.; Pavlinsky, M.; Tkachenko, A.; Lapshov, I.

    2013-01-01

    MSFC is developing eight x-ray mirror modules for the ART-XC instrument on board the SRG Mission. The Engineering Unit tests are successful. MSFC is on schedule to deliver flight units in the November of 2013 and January 2014.

  16. 49 CFR 224.13 - Preemptive effect.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Preemptive effect. 224.13 Section 224.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... effect. Under 49 U.S.C. 20106, issuance of this part preempts any State law, rule, regulation, or order...

  17. 29 CFR 553.224 - “Work period” defined.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false âWork periodâ defined. 553.224 Section 553.224 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS APPLICATION... Enforcement Employees of Public Agencies Tour of Duty and Compensable Hours of Work Rules § 553.224 “Work...

  18. Structural and magnetic properties of FeCoC system obtained by mechanical alloying

    NASA Astrophysics Data System (ADS)

    Rincón Soler, A. I.; Rodríguez Jacobo, R. R.; Medina Barreto, M. H.; Cruz-Muñoz, B.

    2017-11-01

    Fe96-XCoXC4 (x = 0, 10, 20, 30, 40 at. %) alloys were obtained by mechanical alloying of Fe, C and Co powders using high-energy milling. The structural and magnetic properties of the alloy system were analyzed by X-ray diffraction, Scanning Electron Microscopy (SEM), Vibrating Sample Magnetometer (VSM) and Mössbauer Spectrometry at room temperature. The X-ray diffraction patterns showed a BCC-FeCoC structure phase for all samples, as well as a lattice parameter that slightly decreases with Co content. The saturation magnetization and coercive field were analyzed as a function of Co content. The Mössbauer spectra were fitted with a hyperfine magnetic field distribution showing the ferromagnetic behavior and the disordered character of the samples. The mean hyperfine magnetic field remained nearly constant (358 T) with Co content.

  19. 29 CFR 553.224 - “Work period” defined.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false âWork periodâ defined. 553.224 Section 553.224 Labor... Enforcement Employees of Public Agencies Tour of Duty and Compensable Hours of Work Rules § 553.224 “Work period” defined. (a) As used in section 7(k), the term “work period” refers to any established and...

  20. Development of Mirror Modules for the ART-XC Instrument aboard the Spectrum-Roentgen-Gamma Mission

    NASA Technical Reports Server (NTRS)

    Gubarev, M; Ramsey, B.; O'Dell, S. L.; Elsner, R.; Kilaru, K.; McCracken, J.; Pavlinsky, M.; Tkachenko, A.; Lapshov, I.; Atkins, C.; hide

    2013-01-01

    The Marshall Space Flight Center (MSFC) is developing x-ray mirror modules for the ART-XC instrument on board the Spectrum-Roentgen Gamma Mission. Four of those modules are being fabricated under a Reimbursable Agreement between NASA and the Russian Space Research Institute (IKI.) An additional three flight modules and one spare for the ART-XC Instrument are produced under a Cooperative Agreement between NASA and IKI. The instrument will consist of seven co-aligned x-ray mirror modules with seven corresponding CdTe focal plane detectors. Each module consists of 28 nested thin Ni/Co shells giving an effective area of 65 cm2 at 8 keV, response out to 30 keV, and an angular resolution of 45 arcsec or better HPD. Delivery of the first four modules is scheduled for November 2013, while the remaining three modules will be delivered to IKI in January 2014. We present a status of the ART x-ray module development at MSFC.

  1. Development of mirror modules for the ART-XC instrument aboard the Spectrum-Roentgen-Gamma mission

    NASA Astrophysics Data System (ADS)

    Gubarev, M.; Ramsey, B.; O'Dell, S. L.; Elsner, R.; Kilaru, K.; McCracken, J.; Pavlinsky, M.; Tkachenko, A.; Lapshov, I.; Atkins, C.; Zavlin, V.

    2013-09-01

    The Marshall Space Flight Center (MSFC) is developing x-ray mirror modules for the ART-XC instrument on board the Spectrum-Roentgen Gamma Mission. Four of those modules are being fabricated under a Reimbursable Agreement between NASA and the Russian Space Research Institute (IKI.) An additional three flight modules and one spare for the ART-XC Instrument are produced under a Cooperative Agreement between NASA and IKI. The instrument will consist of seven co-aligned x-ray mirror modules with seven corresponding CdTe focal plane detectors. Each module consists of 28 nested thin Ni/Co shells giving an effective area of 65 cm2 at 8 keV, response out to 30 keV, and an angular resolution of 45 arcsec or better HPD. Delivery of the first four modules is scheduled for November 2013, while the remaining three modules will be delivered to IKI in January 2014. We present a status of the ART x-ray module development at MSFC.

  2. MiR-224 expression increases radiation sensitivity of glioblastoma cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Upraity, Shailendra; Kazi, Sadaf; Padul, Vijay

    Highlights: • MiR-224 expression in established glioblastoma cell lines and sporadic tumor tissues is low. • Exogenous miR-224 expression was found to increase radiation sensitivity of glioblastoma cells. • MiR-224 expression brought about 55–60% reduction in API5 expression levels. • Transfection with API5 siRNA increased radiation sensitivity of glioblastoma cells. • Low miR-224 and high API5 expression correlated with worse survival of GBM patients. - Abstract: Glioblastoma (GBM) is the most common and highly aggressive primary malignant brain tumor. The intrinsic resistance of this brain tumor limits the efficacy of administered treatment like radiation therapy. In the present study, effectmore » of miR-224 expression on growth characteristics of established GBM cell lines was analyzed. MiR-224 expression in the cell lines as well as in primary GBM tumor tissues was found to be low. Exogenous transient expression of miR-224 using either synthetic mimics or stable inducible expression using doxycycline inducible lentiviral vector carrying miR-224 gene, was found to bring about 30–55% reduction in clonogenic potential of U87 MG cells. MiR-224 expression reduced clonogenic potential of U87 MG cells by 85–90% on irradiation at a dose of 6 Gy, a dose that brought about 50% reduction in clonogenic potential in the absence of miR-224 expression. MiR-224 expression in glioblastoma cells resulted in 55–65% reduction in the expression levels of API5 gene, a known target of miR-224. Further, siRNA mediated down-regulation of API5 was also found to have radiation sensitizing effect on glioblastoma cell lines. Analysis of the Cancer Genome Atlas data showed lower miR-224 expression levels in male GBM patients to correlate with poorer survival. Higher expression levels of miR-224 target API5 also showed significant correlation with poorer survival of GBM patients. Up-regulation of miR-224 or down-regulation of its target API5 in combination with radiation

  3. 40 CFR 86.224-94 - Carbon dioxide analyzer calibration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Carbon dioxide analyzer calibration. 86.224-94 Section 86.224-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.224-94 Carbon dioxide...

  4. 23 CFR 450.224 - Phase-in of new requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Phase-in of new requirements. 450.224 Section 450.224 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.224 Phase-in of new...

  5. 23 CFR 450.224 - Phase-in of new requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Phase-in of new requirements. 450.224 Section 450.224 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.224 Phase-in of new...

  6. 23 CFR 450.224 - Phase-in of new requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Phase-in of new requirements. 450.224 Section 450.224 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.224 Phase-in of new...

  7. 23 CFR 450.224 - Phase-in of new requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Phase-in of new requirements. 450.224 Section 450.224 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.224 Phase-in of new...

  8. 40 CFR 264.224-264.225 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false [Reserved] 264.224-264.225 Section 264.224-264.225 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES...

  9. 37 CFR 1.122-1.224 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false [Reserved] 1.122-1.224 Section 1.122-1.224 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Amendments...

  10. 25 CFR 224.171 - Who may rescind a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Who may rescind a TERA? 224.171 Section 224.171 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Rescission § 224.171 Who may...

  11. 25 CFR 224.171 - Who may rescind a TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Who may rescind a TERA? 224.171 Section 224.171 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Rescission § 224.171 Who may...

  12. 22 CFR 22.4 - Requests for services, Foreign Service.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Requests for services, Foreign Service. 22.4 Section 22.4 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS SCHEDULE OF FEES FOR CONSULAR SERVICES-DEPARTMENT OF STATE AND FOREIGN SERVICE § 22.4 Requests for services, Foreign Service. Officers of the...

  13. 22 CFR 22.4 - Requests for services, Foreign Service.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Requests for services, Foreign Service. 22.4 Section 22.4 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS SCHEDULE OF FEES FOR CONSULAR SERVICES-DEPARTMENT OF STATE AND FOREIGN SERVICE § 22.4 Requests for services, Foreign Service. Officers of the...

  14. 22 CFR 22.4 - Requests for services, Foreign Service.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Requests for services, Foreign Service. 22.4 Section 22.4 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS SCHEDULE OF FEES FOR CONSULAR SERVICES-DEPARTMENT OF STATE AND FOREIGN SERVICE § 22.4 Requests for services, Foreign Service. Officers of the...

  15. 22 CFR 22.4 - Requests for services, Foreign Service.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Requests for services, Foreign Service. 22.4 Section 22.4 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS SCHEDULE OF FEES FOR CONSULAR SERVICES-DEPARTMENT OF STATE AND FOREIGN SERVICE § 22.4 Requests for services, Foreign Service. Officers of the...

  16. 22 CFR 22.4 - Requests for services, Foreign Service.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Requests for services, Foreign Service. 22.4 Section 22.4 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS SCHEDULE OF FEES FOR CONSULAR SERVICES-DEPARTMENT OF STATE AND FOREIGN SERVICE § 22.4 Requests for services, Foreign Service. Officers of the...

  17. 27 CFR 41.224 - Transfer of ownership.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Transfer of ownership. 41.224 Section 41.224 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO IMPORTATION OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES...

  18. 27 CFR 41.224 - Transfer of ownership.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Transfer of ownership. 41.224 Section 41.224 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO IMPORTATION OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES...

  19. 48 CFR 52.224-2 - Privacy Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Privacy Act. 52.224-2... AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.224-2 Privacy... agency function: Privacy Act (APR 1984) (a) The Contractor agrees to— (1) Comply with the Privacy Act of...

  20. 12 CFR 303.224-303.239 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false [Reserved] 303.224-303.239 Section 303.224-303.239 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE FILING PROCEDURES Section 19 of the FDI Act (Consent to Service of Persons Convicted of Certain Criminal Offenses...

  1. 50 CFR 224.103 - Special prohibitions for endangered marine mammals.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... marine mammals. 224.103 Section 224.103 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS ENDANGERED MARINE AND ANADROMOUS SPECIES § 224.103 Special prohibitions for endangered marine mammals. (a) Approaching...

  2. Anomalous atomic displacement parameters and local dynamics in the Curie range of a Pb-free relaxor ferroelectric system (Bi1-xBax)(Fe1-xTix)O3(0.36 ≤ x ≤ 0.50)

    NASA Astrophysics Data System (ADS)

    Singh, Anar; Moriyoshi, Chikako; Kuroiwa, Yoshihiro; Pandey, Dhananjai

    2018-04-01

    We report here the relaxor ferroelectric (RFE) behaviour in a multiferroic solid solution system, (Bi1-xBax)(Fe1-xTix)O3, at a critical disorder level of xC ˜ 0.35 in BiFeO3 and 0.65 (i.e., 1-xC = 0.35) in BaTiO3 similar to the 1:2 ratio of Mg2+ and Nb5+ in the canonical RFE Pb(Mg1/3Nb2/3)O3. This Pb-free system, like canonical Pb-based RFEs, does not exhibit macroscopic symmetry breaking and shows only the signatures of ergodicity breaking at Vogel-Fulcher freezing temperature (TVF). The atomic displacement parameters (ADPs) of Fe3+/Ti4+ and O2-, obtained using high wave vector (Q) and high-resolution synchrotron x-ray diffraction data as a function of temperature, show anomalous diffuse peaks in the Curie range. It is shown that the diffuse peak in ADPs is due to softening of the vibrational frequencies of the B-O chain (B = Fe3+/Ti4+ and O = O2-) below the Burns temperature (TB) followed by hardening below the characteristic temperature (T'm), which corresponds to a peak in the dielectric permittivity (ɛ').

  3. Alloying effects on structural and thermal behavior of Ti{sub 1-x}Zr{sub x}C: A first principles study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chauhan, Mamta, E-mail: mamta-physics@yahoo.co.in; Gupta, Dinesh C., E-mail: sosfizix@gmail.com

    2016-05-06

    The formation energy, equilibrium lattice parameter, bulk modulus, Debye temperature and heat capacity at constant volume have been calculated for TiC, ZrC, and their intermediate alloys (Ti{sub 1-x}Zr{sub x}C, x = 0,0.25.0.5,0.75,1) using first principles approach. The calculated values of lattice parameter and bulk modulus agree well with the available experimental and earlier theoretical reports. The variation of lattice parameter and bulk modulus with the change in concentration of Zr atom in Ti{sub 1-x}Zr{sub x}C has also been reported. The heat capacities of TiC, ZrC, and their intermediate alloys have been calculated by considering both vibrational and electronic contributions.

  4. 49 CFR 384.224 - Noncommercial motor vehicle violations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Noncommercial motor vehicle violations. 384.224 Section 384.224 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS STATE...

  5. 49 CFR 384.224 - Noncommercial motor vehicle violations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Noncommercial motor vehicle violations. 384.224 Section 384.224 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS STATE...

  6. 48 CFR 3452.224-72 - Research activities involving human subjects.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... involving human subjects. 3452.224-72 Section 3452.224-72 Federal Acquisition Regulations System DEPARTMENT... Text of Provisions and Clauses 3452.224-72 Research activities involving human subjects. As prescribed... human subjects covered under 34 CFR part 97: Research Activities Involving Human Subjects (MAR 2011) (a...

  7. 48 CFR 3452.224-72 - Research activities involving human subjects.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... involving human subjects. 3452.224-72 Section 3452.224-72 Federal Acquisition Regulations System DEPARTMENT... Text of Provisions and Clauses 3452.224-72 Research activities involving human subjects. As prescribed... human subjects covered under 34 CFR part 97: Research Activities Involving Human Subjects (MAR 2011) (a...

  8. 48 CFR 3452.224-72 - Research activities involving human subjects.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... involving human subjects. 3452.224-72 Section 3452.224-72 Federal Acquisition Regulations System DEPARTMENT... Text of Provisions and Clauses 3452.224-72 Research activities involving human subjects. As prescribed... human subjects covered under 34 CFR part 97: Research Activities Involving Human Subjects (MAR 2011) (a...

  9. 48 CFR 3452.224-72 - Research activities involving human subjects.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... involving human subjects. 3452.224-72 Section 3452.224-72 Federal Acquisition Regulations System DEPARTMENT... Text of Provisions and Clauses 3452.224-72 Research activities involving human subjects. As prescribed... human subjects covered under 34 CFR part 97: Research Activities Involving Human Subjects (MAR 2011) (a...

  10. Prospective and retrospective evaluation of the Cepheid Xpert® Flu/RSV XC assay for rapid detection of influenza A, influenza B, and respiratory syncytial virus.

    PubMed

    Salez, Nicolas; Nougairede, Antoine; Ninove, Laetitia; Zandotti, Christine; de Lamballerie, Xavier; Charrel, Remi N

    2015-04-01

    A total of 281 clinical specimens (nasal swabs and nasopharyngeal aspirates) were tested with the Xpert® Flu/RSV XC. The results were compared to those obtained with the real-time retro transcriptase-polymerase chain reaction assays routinely used in our laboratory. The Xpert® Flu/RSV XC showed sensitivity/specificity of 97.8%/100% and 97.9%/100% for flu and respiratory syncytial virus, respectively. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. 48 CFR 1652.224-70 - Confidentiality of records.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Confidentiality of records. 1652.224-70 Section 1652.224-70 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CLAUSES AND FORMS CONTRACT CLAUSES Texts of FEHBP...

  12. 36 CFR 223.224 - Performance bonds and security.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Performance bonds and security. 223.224 Section 223.224 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST BOTANICAL...

  13. 18 CFR 2.24 - Project decommissioning at relicensing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Project decommissioning at relicensing. 2.24 Section 2.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General...

  14. 18 CFR 2.24 - Project decommissioning at relicensing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Project decommissioning at relicensing. 2.24 Section 2.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General...

  15. 18 CFR 2.24 - Project decommissioning at relicensing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Project decommissioning at relicensing. 2.24 Section 2.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General...

  16. 18 CFR 2.24 - Project decommissioning at relicensing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Project decommissioning at relicensing. 2.24 Section 2.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General...

  17. 14 CFR 417.224 - Probability of failure analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Probability of failure analysis. 417.224 Section 417.224 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... phase of normal flight or when any anomalous condition exhibits the potential for a stage or its debris...

  18. 14 CFR 417.224 - Probability of failure analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Probability of failure analysis. 417.224 Section 417.224 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... phase of normal flight or when any anomalous condition exhibits the potential for a stage or its debris...

  19. 14 CFR 417.224 - Probability of failure analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Probability of failure analysis. 417.224 Section 417.224 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... phase of normal flight or when any anomalous condition exhibits the potential for a stage or its debris...

  20. 14 CFR 417.224 - Probability of failure analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Probability of failure analysis. 417.224 Section 417.224 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... phase of normal flight or when any anomalous condition exhibits the potential for a stage or its debris...

  1. 14 CFR 417.224 - Probability of failure analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Probability of failure analysis. 417.224 Section 417.224 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... phase of normal flight or when any anomalous condition exhibits the potential for a stage or its debris...

  2. Magnetic studies of melt spun NdFeAl-C alloys

    NASA Astrophysics Data System (ADS)

    Rodríguez Torres, C. E.; Cabrera, A. F.; Sánchez, F. H.; Billoni, O. V.; Urreta, S. E.; Fabietti, L. M.

    2004-12-01

    Alloys with compositions Nd 60-xC xFe 30Al 10 ( x=0, 1, 5 and 10) were processed by melt spinning at a tangential speed of 5 m/s. The as-cast ribbons were characterized by X-ray diffraction, Mössbauer Effect spectroscopy and their room temperature hysteresis loops. The substitution of Nd by C is found to affect the phase selection, from mainly DHCP-Nd for x=0 to DHCP-Nd /FCC-Nd for the other ones. Mössbauer spectra of all the as-cast samples indicate that Fe is present in crystalline magnetic phases as well as in a paramagnetic one. The major crystalline phase was identified as a μ-type (or A1) metastable phase, which is reported to have a large anisotropy field and a relatively high saturation polarization. Interstitial C stabilizes the μ-type phase and improves its average hyperfine field. The magnetic measurements display an increase of coercivity and remanence with the C concentration.

  3. 22 CFR 224.44 - Right to administrative offset.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Right to administrative offset. 224.44 Section 224.44 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD... against a refund of an overpayment of Federal taxes, then or later owning by the United States to the...

  4. 2,2,4-Trimethylpentane

    Integrated Risk Information System (IRIS)

    2,2,4 - Trimethylpentane ; CASRN 540 - 84 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarci

  5. Singlet-triplet energy differences in divalent five membered cyclic conjugated Arduengo-type carbenes XC2HN2M (M = C, Si, Ge, Sn, and Pb; X = F, Cl, Br, and I)

    NASA Astrophysics Data System (ADS)

    Vessally, Esmail; Dehbandi, Behnam; Ahmadi, Elaheh

    2016-09-01

    Singlet-triplet energy differences in Arduengo-type carbenes XC2HN2C compared and contrasted with their sila, germa, stana and plumba analogues; at B3LYP/6-311++G** level of theory. Free Gibbs energy differences between triplet (t) and singlet (s) states (Δ G(t-s)) change in the following order: plumbylenes > stannylenes > germylenes > silylenes > carbenes. The singlet states in XC2HN2C are generally more stable when the electron withdrawing groups such as-F was used at β-position. However, the singlet states in XC2N2HM (M = Si, Ge, Sn, and Pb) are generally more stable when the withdrawing groups such as-F was placed. The puckering energy is investigated for each the singlet and triplet states. The DFT calculations found the linear correlation to size of the group 14 divalent element (M), the ∠N-M-N angle, and the Δ(LUMO-HOMO) of XC2HN2M.

  6. 4 CFR 22.4 - Appeal File [Rule 4].

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... contracting officer relied in making the decision, and any correspondence relating thereto; (v) Transcripts of... 4 Accounts 1 2010-01-01 2010-01-01 false Appeal File [Rule 4]. 22.4 Section 22.4 Accounts... consisting of all documents pertinent to the appeal, including: (i) The decision from which the appeal is...

  7. Flyover noise characteristics of a tilt-wing V/STOL aircraft (XC-142A)

    NASA Technical Reports Server (NTRS)

    Pegg, R. J.; Henderson, H. R.; Hilton, D. A.

    1974-01-01

    A field noise measurement investigation was conducted during the flight testing of an XC-142A tilt-wing V/STOL aircraft to define its external noise characteristics. Measured time histories of overall sound pressure level show that noise levels are higher at lower airspeeds and decrease with increased speed up to approximately 160 knots. The primary noise sources were the four high-speed, main propellers. Flyover-noise time histories calculated by existing techniques for propeller noise prediction are in reasonable agreement with the experimental data.

  8. 22 CFR 224.31 - Determining the amount of penalties and assessments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... assessments. 224.31 Section 224.31 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.31 Determining the amount of penalties and assessments. (a) In determining an appropriate amount of civil penalties and assessments, the ALJ and the A.I.D...

  9. 22 CFR 224.31 - Determining the amount of penalties and assessments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... assessments. 224.31 Section 224.31 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.31 Determining the amount of penalties and assessments. (a) In determining an appropriate amount of civil penalties and assessments, the ALJ and the A.I.D...

  10. 22 CFR 224.31 - Determining the amount of penalties and assessments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... assessments. 224.31 Section 224.31 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.31 Determining the amount of penalties and assessments. (a) In determining an appropriate amount of civil penalties and assessments, the ALJ and the A.I.D...

  11. 22 CFR 224.31 - Determining the amount of penalties and assessments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... assessments. 224.31 Section 224.31 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.31 Determining the amount of penalties and assessments. (a) In determining an appropriate amount of civil penalties and assessments, the ALJ and the A.I.D...

  12. 22 CFR 224.31 - Determining the amount of penalties and assessments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... assessments. 224.31 Section 224.31 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.31 Determining the amount of penalties and assessments. (a) In determining an appropriate amount of civil penalties and assessments, the ALJ and the A.I.D...

  13. 22 CFR 224.22 - Exchange of witness lists, statements, and exhibits.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Exchange of witness lists, statements, and exhibits. 224.22 Section 224.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.22 Exchange of witness lists, statements, and exhibits. (a...

  14. 22 CFR 224.22 - Exchange of witness lists, statements, and exhibits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Exchange of witness lists, statements, and exhibits. 224.22 Section 224.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.22 Exchange of witness lists, statements, and exhibits. (a...

  15. 22 CFR 224.22 - Exchange of witness lists, statements, and exhibits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Exchange of witness lists, statements, and exhibits. 224.22 Section 224.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.22 Exchange of witness lists, statements, and exhibits. (a...

  16. 22 CFR 224.22 - Exchange of witness lists, statements, and exhibits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Exchange of witness lists, statements, and exhibits. 224.22 Section 224.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.22 Exchange of witness lists, statements, and exhibits. (a...

  17. 22 CFR 224.22 - Exchange of witness lists, statements, and exhibits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Exchange of witness lists, statements, and exhibits. 224.22 Section 224.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.22 Exchange of witness lists, statements, and exhibits. (a...

  18. 49 CFR Appendix B to Part 224 - Reflectorization Implementation Compliance Report

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Reflectorization Implementation Compliance Report B Appendix B to Part 224 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK Pt. 224, App. B Appendix B to Part 224...

  19. 31 CFR 224.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.2... surety bond. (b) Process agent means a resident agent for service of process. (c) State means a State...

  20. 31 CFR 224.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.2... surety bond. (b) Process agent means a resident agent for service of process. (c) State means a State...

  1. 31 CFR 224.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.2... surety bond. (b) Process agent means a resident agent for service of process. (c) State means a State...

  2. 31 CFR 224.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.2 Definitions. For purposes of this regulation: (a) Principal means the person or entity required to provide a...

  3. 25 CFR 224.170 - What is the purpose of this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What is the purpose of this subpart? 224.170 Section 224.170 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Rescission § 224...

  4. 25 CFR 224.170 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the purpose of this subpart? 224.170 Section 224.170 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Rescission § 224...

  5. 25 CFR 224.173 - How does a tribe rescind a TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How does a tribe rescind a TERA? 224.173 Section 224.173 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Rescission § 224.173 How...

  6. MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Maomao; Deng, Xiaodong; Ying, Qi

    2015-05-01

    MicroRNA-224 is overexpressed in various malignant tumors with poor prognosis, which plays a critical role in biological processes including cell proliferation, apoptosis and several developmental and physiological progressions. However, the potential association between miR-224 and clinical outcome in patients with meningiomas remains unknown. Here, we investigate miR-224 expression and biological functions in meningiomas. MiR-224 expression was measured by Northern blot analysis and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) in meningioma and normal brain tissues. Kaplan–Meier analysis and Cox regression analysis were used to exam its correlation with clinicopathological features and prognostic value. The biological effects of miR-224 on the cellmore » proliferation and apoptosis in meningioma cells were examined by MTT assay and apoptosis assay. We found the expression levels of miR-224 were significantly higher in meningioma tissues than that in normal brain, positively correlated with advanced pathological grade. Kaplan–Meier analysis indicated that meningioma patients with low miR-224 expression exhibited significantly prolonged overall and recurrence-free survival. Furthermore, we demonstrated that ERG2 was an identical candidate target gene of MiR-224 in vitro. Our results indicated that downregulation of miR-224 suppressed cell growth and resulted in the enhancement of cell apoptosis through activation of the ERG2-BAK-induced apoptosis pathway. Our findings imply the miR-224 expression could predict the overall survival and recurrence-free survival of patients with meningioma and it might be a promising therapeutic target for treating malignant meningiomas. - Highlights: • MiR-224 expression is correlates with prognosis in meningioma patients. • ERG2 is a novel downstream target of miR-224. • MiR-224 suppressed cell growth and enhanced apoptosis in IOMM-Lee and CH157 cells. • MiR-224 is an upstream regulator of

  7. 25 CFR 224.54 - How must a tribe submit an application?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true How must a tribe submit an application? 224.54 Section 224... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

  8. The Marshall Space Flight Center Development of Mirror Modules for the ART-XC Instrument aboard the Spectrum-Roentgen-Gamma Mission

    NASA Technical Reports Server (NTRS)

    Gubarev, Mikhail V.; Ramsey, B.; ODell, S. L.; Elsner, R.; Kilaru, K.; McCracken, J.; Pavlinsky, M.; Tkachenko, A.; Lapshov, I.

    2012-01-01

    The Marshall Space Flight Center (MSFC) is developing x-ray mirror modules for the ART-XC instrument on board the Spectrum-Roentgen Gamma Mission under a Reimbursable Agreement between NASA and the Russian Space Research Institute (IKI.) ART-XC will consist of seven co-aligned x-ray mirror modules with seven corresponding CdTe focal plane detectors. Currently, four of the modules are being fabricated by the Marshall Space Flight Center (MSFC.) Each MSFC module consist of 28 nested Ni/Co thin shells giving an effective area of 65 sq cm at 8 keV, response out to 30 keV, and an angular resolution of 45 arcsec or better HPD. Delivery of these modules to the IKI is scheduled for summer 2013. We present a status of the ART x-ray modules development at the MSFC.

  9. The Marshall Space Flight Center development of mirror modules for the ART-XC instrument aboard the Spectrum-Roentgen-Gamma mission

    NASA Astrophysics Data System (ADS)

    Gubarev, M.; Ramsey, B.; O'Dell, S. L.; Elsner, R.; Kilaru, K.; McCracken, J.; Pavlinsky, M.; Tkachenko, A.; Lapshov, I.

    2012-09-01

    The Marshall Space Flight Center (MSFC) is developing x-ray mirror modules for the ART-XC instrument on board the Spectrum-Roentgen-Gamma Mission under a Reimbursable Agreement between NASA and the Russian Space Research Institute (IKI.) ART-XC will consist of seven co-aligned x-ray mirror modules with seven corresponding CdTe focal plane detectors. Currently, four of the modules are being fabricated by the Marshall Space Flight Center (MSFC.) Each MSFC module consist of 28 nested Ni/Co thin shells giving an effective area of 65 cm2 at 8 keV, response out to 30 keV, and an angular resolution of 45 arcsec or better HPD. Delivery of these modules to the IKI is scheduled for summer 2013. We present a status of the ART x-ray modules development at the MSFC.

  10. The biological effects of radium-224 injected into dogs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Muggenburg, B.A.; Hahn, F.F.; Boecker, B.B.

    1996-08-01

    A life-span study was conducted in 128 beagle dogs to determine the biological effects of intravenously injected {sup 224}Ra chloride. The {sup 224}Ra chloride was prepared by the same method used for intravenous injections in humans who were treated for ankylosing spondylitis and tuberculosis. Thus the results obtained from dogs can be compared directly to the population of treated humans, both for the elucidation of the effect of exposure rate and for comparison with other radionuclides for which data for humans are unavailable. Using equal numbers of males and females, the dogs were injected with one of four levels ofmore » {sup 224}Ra resulting in initial body burdens of approximately 13, 40, 120 or 350 kBq of {sup 224}Ra kg{sup -1} body mass. A control group of dogs was injected with diluent only. All dogs were divided further into three groups for which the amount of injected {sup 224}Ra (half-life of 3.62 days) or diluent was given in a single injection or divided equally into 10 or 50 weekly injections. As a result of these three injection schedules, the accumulation of dose from the injected {sup 224}Ra was distributed over approximately 1, 3 or 12 months. Each injection schedule included four different injection levels resulting in average absorbed {alpha}-particle doses to bone of 0.1, 0.3, 1 and 3 Gy, respectively. The primary early effect observed was a hematological dyscrasia in the dogs receiving either of the two highest injection levels. The effect was most severe in the dogs receiving a single injection of {sup 224}Ra and resulted in the death of three dogs injected at the highest level. The late-occurring biological effects were tumors. Bone tumors were the most common followed by tumors in the nasal mucosa. 52 refs., 8 figs., 8 tabs.« less

  11. Detailed investigation of Na2.24FePO4CO3 as a cathode material for Na-ion batteries

    PubMed Central

    Huang, Weifeng; Zhou, Jing; Li, Biao; Ma, Jin; Tao, Shi; Xia, Dingguo; Chu, Wangsheng; Wu, Ziyu

    2014-01-01

    Na-ion batteries are gaining an increased recognition as the next generation low cost energy storage devices. Here, we present a characterization of Na3FePO4CO3 nanoplates as a novel cathode material for sodium ion batteries. First-principles calculations reveal that there are two paths for Na ion migration along b and c axis. In-situ and ex-situ Fe K-edge X-ray absorption near edge structure (XANES) point out that in Na3FePO4CO3 both Fe2+/Fe3+ and Fe3+/Fe4+ redox couples are electrochemically active, suggesting also the existence of a two-electron intercalation reaction. Ex-situ X-ray powder diffraction data demonstrates that the crystalline structure of Na3FePO4CO3 remains stable during the charging/discharging process within the range 2.0–4.55 V. PMID:24595232

  12. Corrosion behavior of pre-oxidized HR-224 superalloy in supercritical water environment at 700 °C

    NASA Astrophysics Data System (ADS)

    Liu, Yu-Chen; Chen, Shih-Ming; Ouyang, Fan-Yi; Kai, Ji-Jung

    2018-07-01

    Corrosion of cladding materials in supercritical water (SCW) environment is a key reliability issue for the safety of nuclear power plant. In this study, we propose to use the pre-oxidized treatment to provide better corrosion resistance of cladding materials in the SCW environment. The nickel-based superalloy HR-224 was first pre-oxidized in flowing air at 982 °C for 100 h to establish a continuous and dense scales and then exposed in the SCW environment with high oxygen content (8.3 ppm) at 700 °C and 24.8 MPa for cyclic oxidation testing up to 1300 h. The pre-oxidized samples exhibit better corrosion resistance than as-received samples in the SCW environment. After pre-oxidizing process, triple scales, Ni(Cr, Fe)2O4 spinel/Cr2O3/α-Al2O3 were observed, and the growth of inner α-Al2O3 layer is predominant in the SCW environment. The α-Al2O3 layer in pre-oxidized samples was found to effectively decrease outward migration of metal ions in Alloy HR-224 and thus provides better corrosion resistance than as-received samples in SCW environment.

  13. 25 CFR 224.101 - Who is an interested party?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Who is an interested party? 224.101 Section 224.101 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Interested Party Petitions...

  14. 25 CFR 224.101 - Who is an interested party?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Who is an interested party? 224.101 Section 224.101 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Interested Party Petitions...

  15. 49 CFR 224.5 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.5 Definitions. Administrator means the Administrator of the Federal Railroad Administration or the Administrator's delegate. Associate Administrator means the Associate Administrator for Safety, Federal Railroad Administration, or the Associate...

  16. 49 CFR 224.5 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.5 Definitions. Administrator means the Administrator of the Federal Railroad Administration or the Administrator's delegate. Associate Administrator means the Associate Administrator for Safety, Federal Railroad Administration, or the Associate...

  17. 49 CFR 224.5 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.5 Definitions. Administrator means the Administrator of the Federal Railroad Administration or the Administrator's delegate. Associate Administrator means the Associate Administrator for Safety, Federal Railroad Administration, or the Associate...

  18. 12 CFR 224.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SECURITIES CREDIT (REGULATION X) § 224.2 Definitions. The terms used in this part have the meanings given to... total value of shares of all classes of stock. [Reg. X, 48 FR 56572, Dec. 22, 1983, as amended by Reg. X...

  19. 12 CFR 224.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SECURITIES CREDIT (REGULATION X) § 224.2 Definitions. The terms used in this part have the meanings given to... total value of shares of all classes of stock. [Reg. X, 48 FR 56572, Dec. 22, 1983, as amended by Reg. X...

  20. 7 CFR 1280.224 - Periodic evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE LAMB PROMOTION, RESEARCH, AND INFORMATION ORDER Lamb Promotion, Research, and Information Order Reports, Books, and Records § 1280.224...

  1. 40 CFR 86.224-94 - Carbon dioxide analyzer calibration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Carbon dioxide analyzer calibration. 86.224-94 Section 86.224-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission Regulations for 1994 and Later Model Year...

  2. Magnetization reversal and coercivity of Fe3Se4 nanowire arrays

    NASA Astrophysics Data System (ADS)

    Li, D.; Li, S. J.; Zhou, Y. T.; Bai, Y.; Zhu, Y. L.; Ren, W. J.; Long, G.; Zeng, H.; Zhang, Z. D.

    2015-05-01

    The microstructure and magnetic properties of Fe3Se4 nanowire (NW) arrays in anodic aluminum oxide (AAO) porous membrane are studied. Cross-sectional SEM and plane-view TEM images show that the mean wire diameter (dw) and the center-to-center spacing (D) of Fe3Se4 nanowires are about 220 nm and 330 nm, respectively. The field-cooled magnetization dependent on the temperature indicates a Curie temperature around 334 K for the Fe3Se4 nanowires. The coercivities of Fe3Se4 nanowires at 10 K, obtained from the in-plane and out-of-plane hysteresis loops, are as high as 22.4 kOe and 23.3 kOe, which can be understood from the magnetocrystalline anisotropy and the magnetization reversal process.

  3. 25 CFR 224.81 - What laws are applicable to activities?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 224.81 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Implementation of Tribal Energy Resource Agreements Applicable Authorities and Responsibilities § 224.81 What laws are...

  4. 29 CFR 2.24 - Procedure in the event of an adverse ruling.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Procedure in the event of an adverse ruling. 2.24 Section 2.24 Labor Office of the Secretary of Labor GENERAL REGULATIONS Employees Served With Subpoenas § 2.24 Procedure in the event of an adverse ruling. If the court or other authority declines to stay the effect of...

  5. 25 CFR 224.151 - When may the Secretary reassume activities?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false When may the Secretary reassume activities? 224.151 Section 224.151 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  6. 25 CFR 224.58 - What is an application consultation meeting?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is an application consultation meeting? 224.58 Section 224.58 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  7. 50 CFR 224.103 - Special prohibitions for endangered marine mammals.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... marine mammals. 224.103 Section 224.103 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... approach is authorized by the National Marine Fisheries Service through a permit issued under part 222... section do not apply if a right whale approach is authorized by the National Marine Fisheries Service...

  8. 25 CFR 224.182 - What is the Initial Appeal Process?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What is the Initial Appeal Process? 224.182 Section 224.182 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Appeal...

  9. 25 CFR 224.182 - What is the Initial Appeal Process?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the Initial Appeal Process? 224.182 Section 224.182 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Appeal...

  10. 25 CFR 224.160 - How will reassumption affect a TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How will reassumption affect a TERA? 224.160 Section 224.160 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Reassumption...

  11. 25 CFR 224.160 - How will reassumption affect a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How will reassumption affect a TERA? 224.160 Section 224.160 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Reassumption...

  12. 25 CFR 224.81 - What laws are applicable to activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What laws are applicable to activities? 224.81 Section 224.81 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Implementation of...

  13. 31 CFR 224.4 - When must a surety corporation appoint a process agent?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... a process agent? 224.4 Section 224.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.4 When must a surety corporation appoint a process agent? A...

  14. 31 CFR 224.4 - When must a surety corporation appoint a process agent?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... a process agent? 224.4 Section 224.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.4 When must a surety corporation appoint a process agent? A...

  15. 31 CFR 224.4 - When must a surety corporation appoint a process agent?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... a process agent? 224.4 Section 224.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.4 When must a surety corporation appoint a process agent? A...

  16. Comparative study of different carbon-supported Fe2O3-Pt catalysts for oxygen reduction reaction.

    PubMed

    Tellez-Cruz, M M; Padilla-Islas, M A; Pérez-González, M; Solorza-Feria, O

    2017-11-01

    One of the challenges in electrocatalysis is the adequate dispersion of the catalyst on an appropriate porous support matrix, being up to now the most commonly used the carbon-based supports. To overcome this challenge, carbon supports must first be functionalized to guide the catalyst's nucleation, thereby, improving the dispersion and allowing the use of smaller amount of the catalyst material to achieve a higher electrochemically active surface area. This study present the effect of functionalized Vulcan carbon XC72 (FVC) and functionalized Black Pearl carbon (FBPC) as supports on the catalytic activity of decorated Fe 2 O 3 with Pt. Both carbons were functionalized with HNO 3 and subsequently treated with ethanolamine. Fe 2 O 3 nanoparticles were synthesized by chemical reduction and decorated with platinum by epitaxial growth. Pt and Fe 2 O 3 structural phases were identified by XRD and XPS; the Pt content was measured by XPS, and results showed to a high Pt content in Fe 2 O 3 -Pt/FBPC. TEM micrographs reveal nanoparticles with an average size of 2 nm in both supported catalysts. The Fe 2 O 3 -Pt/FVC catalyst presents the highest specific activity and mass activity, 0.21 mA cm -2 Pt and 140 mA mg Pt -1 , respectively, associated to the appropriate distribution of platinum on the Fe 2 O 3 nanoparticles.

  17. 31 CFR 224.4 - When must a surety corporation appoint a process agent?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... appoint a process agent? 224.4 Section 224.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.4 When must a surety corporation appoint a process agent? A...

  18. 76 FR 67019 - Tenth Meeting: RTCA Special Committee 224, Airport Security Access Control

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... 224, Airport Security Access Control AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Notice of RTCA Special Committee 224, Airport Security Access Control. SUMMARY: The... (Pub. L. 92-463, 5 U.S.C., App.), notice is hereby given for a Special Committee 224, Airport Security...

  19. XC-142 Tilt Wing; 0.6 Scale Model in the 40x80 Foot Wind Tunnel at NASA Ames Research Center.

    NASA Image and Video Library

    1964-01-22

    3/4 front right side only with Tim Wills on right and Charles Greco, mechanic. Large flaps on Variable height struts. XC-142 was a tri-service tiltwing experimental aircraft designed to investigate the operational suitability of vertical/short takeoff and landing (V/STOL) transports.

  20. 25 CFR 224.151 - When may the Secretary reassume activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Reassumption § 224.151 When may the Secretary reassume activities? Upon issuing a written finding of imminent jeopardy to a physical trust asset, the Secretary may reassume activities under a TERA in accordance with... 25 Indians 1 2010-04-01 2010-04-01 false When may the Secretary reassume activities? 224.151...

  1. 77 FR 37732 - Fourteenth Meeting: RTCA Special Committee 224, Audio Systems and Equipment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... Committee 224, Audio Systems and Equipment AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Audio Systems and Equipment. SUMMARY... Committee 224, Audio Systems and Equipment. DATES: The meeting will be held July 11, 2012, from 10 a.m.-4 p...

  2. Development and Calibration of the ART-XC Mirror Modules for the Spectrum Rontgen Gamma Mission

    NASA Technical Reports Server (NTRS)

    Ramsey, B.; Gubarev, M.; Elsner, R.; Kolodziejczak, J.; Odell, S.; Swartz, D.; Pavlinsky, M.; Tkachenko, A.; Lapshov, I.

    2013-01-01

    The Spectrum-Röntgen-Gamma (SRG) mission is a Russian-lead X-ray astrophysical observatory that carries two co-aligned X-ray telescope systems. The primary instrument is the German-led extended ROentgen Survey with an Imaging Telescope Array (eROSITA), a 7-module X-ray telescope system that covers the energy range from 0.2-12 keV. The complementary instrument is the Astronomical Roentgen Telescope -- X-ray Concentrator (ART-XC or ART), a 7-module Xray telescope system that provides higher energy coverage, up to 30 keV.

  3. 22 CFR 224.26 - Form, filing and service of papers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Form, filing and service of papers. 224.26... CIVIL REMEDIES ACT § 224.26 Form, filing and service of papers. (a) Form. (1) Documents filed with the ALJ shall include an original and two copies. (2) Every pleading and paper filed in the proceeding...

  4. 22 CFR 224.26 - Form, filing and service of papers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Form, filing and service of papers. 224.26... CIVIL REMEDIES ACT § 224.26 Form, filing and service of papers. (a) Form. (1) Documents filed with the ALJ shall include an original and two copies. (2) Every pleading and paper filed in the proceeding...

  5. 50 CFR 224.102 - Permits for endangered marine and anadromous species.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Permits for endangered marine and anadromous species. 224.102 Section 224.102 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS ENDANGERED MARINE...

  6. 50 CFR 224.102 - Permits for endangered marine and anadromous species.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Permits for endangered marine and anadromous species. 224.102 Section 224.102 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS ENDANGERED MARINE...

  7. 75 FR 80886 - Third Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held January 13, 2011...

  8. 78 FR 16757 - Twentieth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  9. 77 FR 64838 - Sixteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  10. 75 FR 61819 - First Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held November 2, 2010...

  11. 25 CFR 224.68 - How will the Secretary use public comments?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 224.68 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for Obtaining Tribal Energy Resource Agreements Public Notification and Comment § 224.68 How will...

  12. 30 CFR 285.224 - What happens if MMS accepts my bid?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 285.224 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 285.224 What...

  13. Genotype X/C recombinant (putative genotype I) of hepatitis B virus is rare in Hanoi, Vietnam--genotypes B4 and C1 predominate.

    PubMed

    Phung, Thi Bich Thuy; Alestig, Erik; Nguyen, Thanh Liem; Hannoun, Charles; Lindh, Magnus

    2010-08-01

    There are eight known genotypes of hepatitis B virus, A-H, and several subgenotypes, with rather well-defined geographic distributions. HBV genotypes were evaluated in 153 serum samples from Hanoi, Vietnam. Of the 87 samples that could be genotyped, genotype B was found in 67 (77%) and genotype C in 19 (22%). All genotype C strains were of subgenotype C1, and the majority of genotype B strains were B4, while a few were B2. The genotype X/C recombinant strain, identified previously in Swedish patients of indigenous Vietnamese origin, was found in one sample. This variant, proposed to be classified as genotype I, has been found recently also by others in Vietnam and Laos. The current study indicates that the genotype X/C recombinant may represent approximately 1% of the HBV strains circulating in Vietnam. (c) 2010 Wiley-Liss, Inc.

  14. 75 FR 71790 - Second Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held December 9, 2010...

  15. 76 FR 9632 - Fifth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held March 10, 2011, from...

  16. 76 FR 3931 - Fourth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 Meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held February 8, 2011...

  17. 77 FR 55894 - Fifteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems DATES: The meeting will...

  18. 76 FR 16470 - Sixth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems DATES: The meeting will be held April 13, 2011, from...

  19. Spin and orbital disordering by hole doping in P r1 -xC axV O3

    NASA Astrophysics Data System (ADS)

    Reehuis, M.; Ulrich, C.; Abdala, P. M.; Pattison, P.; Khaliullin, G.; Fujioka, J.; Miyasaka, S.; Tokura, Y.; Keimer, B.

    2016-09-01

    High-resolution powder x-ray diffraction and single-crystal neutron diffraction were used to investigate the crystal structure and magnetic ordering of the compound P r1 -xC axV O3 (0 ≤x ≤0.3 ), which undergoes an insulator-to-metal transition for x ˜0.23 . Since the ionic radii of P r3 + and C a2 + are almost identical and structural disorder is minimal, P r1 -xC axV O3 is a good model system for the influence of hole doping on the spin and orbital correlations in transition metal oxides. The end member PrV O3 is a Mott-Hubbard insulator, which exhibits a structural phase transition at TS=180 K from an orthorhombic to a monoclinic structure with space groups Pbnm and P 21/b , respectively. This transition is associated with the onset of orbital ordering and strong Jahn-Teller distortions of the V O6 octahedra. Antiferromagnetic C -type order with vanadium moments oriented in the a b plane is observed below TN=140 K . Upon cooling, the vanadium moments induce a progressive magnetic polarization of the praseodymium sublattice, resulting in a ferrimagnetic structure with coexisting modes (Cx, Fy) and (Fx, Cy). In the insulating range of the P r1 -xC axV O3 phase diagram, Ca doping reduces both the orbital and magnetic transition temperatures so that TS=108 K and TN=95 K for x =0.20 . The Jahn-Teller distortions and ordered vanadium moments also decrease upon doping. In a metallic sample with x =0.30 , Jahn-Teller distortions and long-range orbital ordering are no longer observable, and the average crystal structure remains orthorhombic down to low temperature. However, broadening of some lattice Bragg reflections indicate a significant increase in lattice strain. Antiferromagnetic short-range order with a weak ordered moment of 0.14(3) μB per vanadium atom could still be observed on the vanadium site below T ˜60 K . We discuss these observations in terms of doping-induced spin-orbital polaron formation.

  20. 25 CFR 224.183 - What other administrative appeals processes also apply?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What other administrative appeals processes also apply? 224.183 Section 224.183 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  1. 25 CFR 224.183 - What other administrative appeals processes also apply?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What other administrative appeals processes also apply? 224.183 Section 224.183 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  2. 25 CFR 224.57 - What must the Director do upon receipt of an application?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...? 224.57 Section 224.57 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for Obtaining Tribal Energy Resource Agreements Processing Applications § 224.57 What must the...

  3. 31 CFR 224.8 - When must a surety corporation appoint a new process agent?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... a new process agent? 224.8 Section 224.8 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.8 When must a surety corporation appoint a new process...

  4. 31 CFR 224.8 - When must a surety corporation appoint a new process agent?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... a new process agent? 224.8 Section 224.8 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.8 When must a surety corporation appoint a new process...

  5. 31 CFR 224.8 - When must a surety corporation appoint a new process agent?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... a new process agent? 224.8 Section 224.8 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.8 When must a surety corporation appoint a new process...

  6. 25 CFR 224.185 - When are decisions under this part effective?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When are decisions under this part effective? 224.185 Section 224.185 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General...

  7. 25 CFR 224.184 - How do other administrative appeals processes apply?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How do other administrative appeals processes apply? 224.184 Section 224.184 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  8. 25 CFR 224.150 - What is the purpose of this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What is the purpose of this subpart? 224.150 Section 224.150 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Reassumption...

  9. 25 CFR 224.184 - How do other administrative appeals processes apply?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How do other administrative appeals processes apply? 224.184 Section 224.184 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  10. 25 CFR 224.185 - When are decisions under this part effective?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false When are decisions under this part effective? 224.185 Section 224.185 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General...

  11. 25 CFR 224.174 - When does a voluntary rescission become effective?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false When does a voluntary rescission become effective? 224.174 Section 224.174 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  12. 25 CFR 224.150 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the purpose of this subpart? 224.150 Section 224.150 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Reassumption...

  13. 25 CFR 224.68 - How will the Secretary use public comments?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How will the Secretary use public comments? 224.68 Section 224.68 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  14. 25 CFR 224.174 - When does a voluntary rescission become effective?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When does a voluntary rescission become effective? 224.174 Section 224.174 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  15. Exploratory clinical trial of (4S)-4-(3-[18F]fluoropropyl)-L-glutamate for imaging xC- transporter using positron emission tomography in patients with non-small cell lung or breast cancer.

    PubMed

    Baek, Sora; Choi, Chang-Min; Ahn, Sei Hyun; Lee, Jong Won; Gong, Gyungyub; Ryu, Jin-Sook; Oh, Seung Jun; Bacher-Stier, Claudia; Fels, Lüder; Koglin, Norman; Hultsch, Christina; Schatz, Christoph A; Dinkelborg, Ludger M; Mittra, Erik S; Gambhir, Sanjiv S; Moon, Dae Hyuk

    2012-10-01

    (4S)-4-(3-[(18)F]fluoropropyl)-l-glutamate (BAY 94-9392, alias [(18)F]FSPG) is a new tracer to image x(C)(-) transporter activity with positron emission tomography (PET). We aimed to explore the tumor detection rate of [(18)F]FSPG in patients relative to 2-[(18)F]fluoro-2-deoxyglucose ([(18)F]FDG). The correlation of [(18)F]FSPG uptake with immunohistochemical expression of x(C)(-) transporter and CD44, which stabilizes the xCT subunit of system x(C)(-), was also analyzed. Patients with non-small cell lung cancer (NSCLC, n = 10) or breast cancer (n = 5) who had a positive [(18)F]FDG uptake were included in this exploratory study. PET images were acquired following injection of approximately 300 MBq [(18)F]FSPG. Immunohistochemistry was done using xCT- and CD44-specific antibody. [(18)F]FSPG PET showed high uptake in the kidney and pancreas with rapid blood clearance. [(18)F]FSPG identified all 10 NSCLC and three of the five breast cancer lesions that were confirmed by pathology. [(18)F]FSPG detected 59 of 67 (88%) [(18)F]FDG lesions in NSCLC, and 30 of 73 (41%) in breast cancer. Seven lesions were additionally detected only on [(18)F]FSPG in NSCLC. The tumor-to-blood pool standardized uptake value (SUV) ratio was not significantly different from that of [(18)F]FDG in NSCLC; however, in breast cancer, it was significantly lower (P < 0.05). The maximum SUV of [(18)F]FSPG correlated significantly with the intensity of immunohistochemical staining of x(C)(-) transporter and CD44 (P < 0.01). [(18)F]FSPG seems to be a promising tracer with a relatively high cancer detection rate in patients with NSCLC. [(18)F]FSPG PET may assess x(C)(-) transporter activity in patients with cancer.

  16. 25 CFR 224.65 - How may a tribe assume additional activities under a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...? 224.65 Section 224.65 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for Obtaining Tribal Energy Resource Agreements Tera Requirements § 224.65 How may a tribe assume...

  17. 31 CFR 224.8 - When must a surety corporation appoint a new process agent?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... appoint a new process agent? 224.8 Section 224.8 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.8 When must a surety corporation appoint a new process...

  18. 44 CFR 206.224 - Debris removal.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Debris removal. 206.224... Debris removal. (a) Public interest. Upon determination that debris removal is in the public interest, the Regional Administrator may provide assistance for the removal of debris and wreckage from publicly...

  19. 44 CFR 206.224 - Debris removal.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Debris removal. 206.224... Debris removal. (a) Public interest. Upon determination that debris removal is in the public interest, the Regional Administrator may provide assistance for the removal of debris and wreckage from publicly...

  20. 44 CFR 206.224 - Debris removal.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Debris removal. 206.224... Debris removal. (a) Public interest. Upon determination that debris removal is in the public interest, the Regional Administrator may provide assistance for the removal of debris and wreckage from publicly...

  1. 44 CFR 206.224 - Debris removal.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Debris removal. 206.224... Debris removal. (a) Public interest. Upon determination that debris removal is in the public interest, the Regional Administrator may provide assistance for the removal of debris and wreckage from publicly...

  2. 44 CFR 206.224 - Debris removal.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Debris removal. 206.224... Debris removal. (a) Public interest. Upon determination that debris removal is in the public interest, the Regional Administrator may provide assistance for the removal of debris and wreckage from publicly...

  3. 25 CFR 224.180 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the purpose of this subpart? 224.180 Section 224.180 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Appeal...

  4. 25 CFR 224.130 - What is the purpose of this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What is the purpose of this subpart? 224.130 Section 224.130 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews...

  5. 25 CFR 224.180 - What is the purpose of this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What is the purpose of this subpart? 224.180 Section 224.180 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Appeal...

  6. 25 CFR 224.130 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the purpose of this subpart? 224.130 Section 224.130 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews...

  7. 30 CFR 585.224 - What happens if BOEM accepts my bid?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 585.224 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 585.224 What happens if BOEM accepts my bid? If we...

  8. 30 CFR 585.224 - What happens if BOEM accepts my bid?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 585.224 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 585.224 What happens if BOEM accepts my bid? If we...

  9. 30 CFR 585.224 - What happens if BOEM accepts my bid?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 585.224 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 585.224 What happens if BOEM accepts my bid? If we...

  10. 25 CFR 224.50 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the purpose of this subpart? 224.50 Section 224.50 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for...

  11. 25 CFR 224.54 - How must a tribe submit an application?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How must a tribe submit an application? 224.54 Section 224.54 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for...

  12. 25 CFR 224.59 - How will the Director use the results of the application consultation meeting?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... consultation meeting? 224.59 Section 224.59 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF... information provided through §§ 224.53 and 224.63 to determine the energy resource development capacity of the...

  13. 25 CFR 224.54 - How must a tribe submit an application?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How must a tribe submit an application? 224.54 Section... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

  14. 25 CFR 224.54 - How must a tribe submit an application?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How must a tribe submit an application? 224.54 Section... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

  15. 25 CFR 224.54 - How must a tribe submit an application?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How must a tribe submit an application? 224.54 Section... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

  16. First-order transition from a Kondo insulator to a ferromagnetic metal in single crystalline FeSi(1-x)Ge(x).

    PubMed

    Yeo, S; Nakatsuji, S; Bianchi, A D; Schlottmann, P; Fisk, Z; Balicas, L; Stampe, P A; Kennedy, R J

    2003-07-25

    The phase diagram of FeSi(1-x)Ge(x), obtained from magnetic, thermal, and transport measurements on single crystals, shows a discontinuous transition from Kondo insulator to ferromagnetic metal with x at a critical concentration, x(c) approximately 0.25. The gap of the insulating phase strongly decreases with x. The specific heat gamma coefficient appears to track the density of states of a Kondo insulator. The phase diagram is consistent with an insulator-metal transition induced by a reduction of the hybridization with x in conjunction with disorder on the Si/Ge ligand site.

  17. 22 CFR 224.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224... protective order with respect to discovery sought by an opposing party or, with respect to the hearing..., oppression, or undue burden or expense, including one or more of the following: (1) That the discovery not be...

  18. 78 FR 43963 - Twenty-Third Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  19. 25 CFR 224.173 - How does a tribe rescind a TERA?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true How does a tribe rescind a TERA? 224.173 Section 224.173... does a tribe rescind a TERA? To rescind a TERA, a tribe must submit to the Secretary a written tribal resolution or other official action of the tribe's governing body approving the voluntary rescission of the...

  20. 25 CFR 224.173 - How does a tribe rescind a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How does a tribe rescind a TERA? 224.173 Section 224.173... does a tribe rescind a TERA? To rescind a TERA, a tribe must submit to the Secretary a written tribal resolution or other official action of the tribe's governing body approving the voluntary rescission of the...

  1. 25 CFR 224.173 - How does a tribe rescind a TERA?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How does a tribe rescind a TERA? 224.173 Section 224.173... does a tribe rescind a TERA? To rescind a TERA, a tribe must submit to the Secretary a written tribal resolution or other official action of the tribe's governing body approving the voluntary rescission of the...

  2. 25 CFR 224.173 - How does a tribe rescind a TERA?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How does a tribe rescind a TERA? 224.173 Section 224.173... does a tribe rescind a TERA? To rescind a TERA, a tribe must submit to the Secretary a written tribal resolution or other official action of the tribe's governing body approving the voluntary rescission of the...

  3. 14 CFR 13.224 - Burden of proof.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Rules of Practice in FAA Civil Penalty Actions § 13.224 Burden of proof... otherwise provided by statute or rule, the proponent of a motion, request, or order has the burden of proof...

  4. Magnetic phase diagrams of amorphous (Ni100-xFex)-metalloid alloys: The key role of the electronic density of states at the Fermi level for the onset of magnetic order

    NASA Astrophysics Data System (ADS)

    Kiss, L. F.; Bakonyi, I.

    2017-11-01

    There have been extended studies on the appearance of ferromagnetism in transition-metal-metalloid (MD) glasses. In particular, the paramagnetic (PM) to ferromagnetic (FM) transition has been investigated on numerous (Ni100-xFex)-MD alloys upon the introduction of Fe where MD can represent a combination of various metalloid elements, while keeping the metal/metalloid ratio constant. It has been reported that adding a sufficient amount of Fe to a Pauli PM Ni-MD alloy matrix first induces a spin-glass (SG) state at low temperatures which goes over to a PM state at higher temperatures. Beyond a certain Fe content, xc, the SG state transforms to a FM state upon increasing the temperature. By plotting the characteristic transition temperatures as a function of the Fe content, a magnetic phase diagram can be constructed for each Ni-Fe-MD system which has a multicritical point (MCP) at xc. By using the reported magnetic phase diagrams of various Ni-Fe-MD alloy systems, it is shown that the critical Fe content, xc scales inversely with the density of states at the Fermi level, N(EF), of the parent Ni-MD matrix. This means that the higher the N(EF), the lower the critical Fe content to induce ferromagnetism in the Ni-MD matrix. This is then discussed in terms of the Stoner enhancement factor, S, which characterizes the tendency of the matrix to become ferromagnetic.

  5. 28 CFR 2.24 - Review of panel recommendation by the Regional Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Review of panel recommendation by the Regional Commissioner. 2.24 Section 2.24 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code...

  6. 28 CFR 2.24 - Review of panel recommendation by the Regional Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Review of panel recommendation by the Regional Commissioner. 2.24 Section 2.24 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code...

  7. Evolution of critical pressure with increasing Fe substitution in the heavy-fermion system URu 2 - x Fe x Si 2

    DOE PAGES

    Wolowiec, C. T.; Kanchanavatee, N.; Huang, K.; ...

    2016-08-29

    Measurements of electrical resistivity, ρ(T ), were performed under quasihydrostatic pressure up to P ~ 2.2 GPa to determine the pressure dependence of the so-called hidden order (HO) and large-moment antiferromagnetic (LMAFM) phases for the URu 2-xFexSi2 system with x = 0.025, 0.05, 0.10, 0.15, and 0.20. As the Fe concentration (x) is increased, we observed that a smaller amount of external pressure, P c, is required to induce the HO → LMAFM phase transition. A critical pressure of P c ~ 1.2 GPa at x = 0.025 reduces to P c ~ 0 at x = 0.15, suggesting themore » URu 2-xFe xSi 2 system is fully expressed in the LMAFM phase for x ≥ x* c = 0.15, where x * c denotes the ambient pressure critical concentration of Fe. Furthermore, when using a bulk modulus calculation to convert x to chemical pressure, P ch(x), we consistently found that the induced HO → LMAFM phase transition occurred at various combinations of x c and P c such that P ch(x c) + P c ≈ 1.5 GPa, where xc denotes those critical concentrations of Fe that induce the HO→LMAFM phase transition for the URu 2-xFe xSi 2 compounds under pressure. We performed exponential fits of ρ(T ) in the HO and LMAFM phases in order to determine the pressure dependence of the energy gap, , that opens over part of the Fermi surface in the transition from the paramagnetic (PM) phase to the HO/LMAFM phase at the transition temperature, T 0. Finally, this change in the pressure variation of Δ(P) at the HO→LMAFM phase transition is consistent with the values of P c determined from the T 0(P) phase lines at the PM→HO/LMAFM transition.« less

  8. 25 CFR 224.103 - Must a tribe establish other public participation processes?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Must a tribe establish other public participation processes? 224.103 Section 224.103 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  9. 25 CFR 224.103 - Must a tribe establish other public participation processes?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Must a tribe establish other public participation processes? 224.103 Section 224.103 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  10. 18 CFR 284.224 - Certain transportation and sales by local distribution companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Certain transportation and sales by local distribution companies. 284.224 Section 284.224 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY OTHER REGULATIONS UNDER THE NATURAL GAS...

  11. 25 CFR 224.74 - When must the Secretary approve or disapprove a final proposed TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... proposed TERA? 224.74 Section 224.74 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Approval of Tribal Energy Resource Agreements § 224.74 When must the Secretary approve or...

  12. 31 CFR 224.5 - Who may a surety corporation appoint to be a process agent?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... to be a process agent? 224.5 Section 224.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.5 Who may a surety corporation appoint to be a process...

  13. 25 CFR 224.135 - Under what circumstances may the Director conduct additional reviews and evaluations?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... harm to a physical trust asset, previously identified in a periodic review and evaluation, exists; or... additional reviews and evaluations? 224.135 Section 224.135 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews § 224.135 Under what circumstances may the Director...

  14. 31 CFR 224.5 - Who may a surety corporation appoint to be a process agent?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... to be a process agent? 224.5 Section 224.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.5 Who may a surety corporation appoint to be a process...

  15. 31 CFR 224.5 - Who may a surety corporation appoint to be a process agent?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... to be a process agent? 224.5 Section 224.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.5 Who may a surety corporation appoint to be a process...

  16. 27 CFR 9.224 - Wisconsin Ledge.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Wisconsin Ledge. 9.224... Wisconsin Ledge. (a) Name. The name of the viticultural area described in this section is “Wisconsin Ledge”. For purposes of part 4 of this chapter, “Wisconsin Ledge” is a term of viticultural significance. (b...

  17. 27 CFR 9.224 - Wisconsin Ledge.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Wisconsin Ledge. 9.224... Wisconsin Ledge. (a) Name. The name of the viticultural area described in this section is “Wisconsin Ledge”. For purposes of part 4 of this chapter, “Wisconsin Ledge” is a term of viticultural significance. (b...

  18. 27 CFR 9.224 - Wisconsin Ledge.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Wisconsin Ledge. 9.224... Wisconsin Ledge. (a) Name. The name of the viticultural area described in this section is “Wisconsin Ledge”. For purposes of part 4 of this chapter, “Wisconsin Ledge” is a term of viticultural significance. (b...

  19. Prognostic Value of microRNA-224 in Various Cancers: A Meta-analysis.

    PubMed

    Zhang, Yue; Guo, Cong-Cong; Guan, Dong-Hui; Yang, Chuan-Hua; Jiang, Yue-Hua

    2017-07-01

    During previous studies, microRNA-224 (miR-224) was frequently investigated and discovered to be of vital significance to prognosis of patients with various cancers. However, its accurate prognostic value has not been estimated worldwide. Herein, we performed meta-analysis to assess its potential predictive value in a variety of human tumors. Qualified researches were identified up to March 1, 2017 through performing online searches in PubMed, EMBASE, Web of Science and Cochrane Database of Systematic Reviews. Overall survival (OS), disease-free survival (DFS) or progression-free survival (PFS) as a prognosis for various cancers were extracted and calculated, if available. Pooled hazard ratios (HR) and 95% confidence intervals (CI) were calculated using Stata version 13.0 (StataCorp, College Station, Texas, USA). 22 eligible studies with 3000 patients were ultimately brought into the current meta-analysis. It suggested that high miR-224 expression was significantly associated with poor OS in tissue (HR = 1.43, 95% CI = 1.00-2.03). During multivariate analysis, high miR-224 expression was more significantly associated with OS in tissue (HR = 2.81, 95% CI = 1.91-4.13). Likewise, there were significant associations between tissue miR-224 expression and colorectal cancer (CRC), diffuse large B-cell lymphoma (DLBCL) and gastric cancer (GC) patients (p <0.05). Nevertheless, there were not significant associations between high tissue miR-224 expression and DFS (HR = 2.15, 95% CI = 0.97-4.79) or PFS (HR = 0.92, 95% CI = 0.53-1.59). As far as the present researches are concerned, tissue miR-224 has a significantly prognostic value in various cancers, especially in CRC, DLBCL and GC. Due to the complicated pathogenesis of cancers, more large-scale and standard researches are requisite. Copyright © 2017 IMSS. Published by Elsevier Inc. All rights reserved.

  20. Influence of xc functional on thermal-elastic properties of Ceria: A DFT-based Debye-Grüneisen model approach

    NASA Astrophysics Data System (ADS)

    Lee, Ji-Hwan; Tak, Youngjoo; Lee, Taehun; Soon, Aloysius

    Ceria (CeO2-x) is widely studied as a choice electrolyte material for intermediate-temperature (~ 800 K) solid oxide fuel cells. At this temperature, maintaining its chemical stability and thermal-mechanical integrity of this oxide are of utmost importance. To understand their thermal-elastic properties, we firstly test the influence of various approximations to the density-functional theory (DFT) xc functionals on specific thermal-elastic properties of both CeO2 and Ce2O3. Namely, we consider the local-density approximation (LDA), the generalized gradient approximation (GGA-PBE) with and without additional Hubbard U as applied to the 4 f electron of Ce, as well as the recently popularized hybrid functional due to Heyd-Scuseria-Ernzehof (HSE06). Next, we then couple this to a volume-dependent Debye-Grüneisen model to determine the thermodynamic quantities of ceria at arbitrary temperatures. We find an explicit description of the strong correlation (e.g. via the DFT + U and hybrid functional approach) is necessary to have a good agreement with experimental values, in contrast to the mean-field treatment in standard xc approximations (such as LDA or GGA-PBE). We acknowledge support from Samsung Research Funding Center of Samsung Electronics (SRFC-MA1501-03).

  1. 25 CFR 224.110 - What must a petition to the Secretary contain?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must a petition to the Secretary contain? 224.110 Section 224.110 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  2. 25 CFR 224.110 - What must a petition to the Secretary contain?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What must a petition to the Secretary contain? 224.110 Section 224.110 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  3. 49 CFR Appendix A to Part 224 - Schedule of Civil Penalties1

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Schedule of Civil Penalties1 A Appendix A to Part 224 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Appendix A to Part 224—Schedule of Civil Penalties1 Subpart B—Application, Inspection, and Maintenance of...

  4. Tachykinin antagonist FK224 inhibits neurokinin A-, substance P- and capsaicin-induced human bronchial contraction.

    PubMed

    Honda, I; Kohrogi, H; Yamaguchi, T; Hamamoto, J; Hirata, N; Iwagoe, H; Fujii, K; Goto, E; Ando, M

    1997-01-01

    To determine the roles of endogenously released tachykinins (substance P [SP] and neurokinin A [NKA]) in the human bronchial tissues, we studied the effects of tachykinin antagonist FK224 on bronchial smooth muscle contraction induced by SP, NKA and capsaicin in an organ bath. FK224 (10(-6) M and 10(-5) M, respectively) significantly inhibited NKA-induced contraction and 10(-5) M FK224 shifted the dose-response curve to more than one log unit higher concentration. Because SP- and capsaicin-induced contractions were small, we pretreated the tissues with the neutral endopeptidase inhibitor phosphoramidon (10(-5) M), which inhibits degradation of exogenous tachykinins in order to potentiate the contractions. FK224 (10(-5) M) significantly inhibited SP-induced contraction and it shifted the dose-response curves to about one log unit higher concentration. FK224 (10(-5) M) also significantly inhibited capsaicin-induced contraction and it shifted the dose-response curves to more than one log unit higher concentration. In contrast, FK224 (10(-5) M) did not affect on acetylcholine-, histamine-, and leukotriene D4-induced contraction. These results suggest that FK224 is a tachykinin receptor antagonist in the human bronchial smooth muscle, and that capsaicin-induced contraction is due to endogenously released tachykinin-like substances in the human bronchus.

  5. 30 CFR 22.4 - Application procedures and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS PORTABLE METHANE DETECTORS § 22.4 Application procedures and requirements. (a) Before MSHA will undertake an active investigation leading to approval of any methane...

  6. 25 CFR 900.224 - What happens if the decision does not come within that time?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What happens if the decision does not come within that time? 900.224 Section 900.224 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN... EDUCATION ASSISTANCE ACT Post-Award Contract Disputes § 900.224 What happens if the decision does not come...

  7. 25 CFR 900.224 - What happens if the decision does not come within that time?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What happens if the decision does not come within that time? 900.224 Section 900.224 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN... EDUCATION ASSISTANCE ACT Post-Award Contract Disputes § 900.224 What happens if the decision does not come...

  8. 25 CFR 900.224 - What happens if the decision does not come within that time?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What happens if the decision does not come within that time? 900.224 Section 900.224 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN... EDUCATION ASSISTANCE ACT Post-Award Contract Disputes § 900.224 What happens if the decision does not come...

  9. 25 CFR 900.224 - What happens if the decision does not come within that time?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What happens if the decision does not come within that time? 900.224 Section 900.224 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN... EDUCATION ASSISTANCE ACT Post-Award Contract Disputes § 900.224 What happens if the decision does not come...

  10. 25 CFR 900.224 - What happens if the decision does not come within that time?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What happens if the decision does not come within that time? 900.224 Section 900.224 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN... EDUCATION ASSISTANCE ACT Post-Award Contract Disputes § 900.224 What happens if the decision does not come...

  11. 31 CFR 224.5 - Who may a surety corporation appoint to be a process agent?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to be a process agent? 224.5 Section 224.5 Money and Finance: Treasury Regulations Relating to Money... FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.5 Who may a surety corporation appoint to be a process agent? A surety corporation may appoint either of the following as process agent—(a) An official of the...

  12. Ra-224 labeling of calcium carbonate microparticles for internal α-therapy: Preparation, stability, and biodistribution in mice.

    PubMed

    Westrøm, Sara; Malenge, Marion; Jorstad, Ida Sofie; Napoli, Elisa; Bruland, Øyvind S; Bønsdorff, Tina B; Larsen, Roy H

    2018-05-30

    Internal therapy with α-emitters should be well suited for micrometastatic disease. Radium-224 emits multiple α-particles through its decay and has a convenient 3.6 days of half-life. Despite its attractive properties, the use of 224 Ra has been limited to bone-seeking applications because it cannot be stably bound to a targeting molecule. Alternative delivery systems for 224 Ra are therefore of considerable interest. In this study, calcium carbonate microparticles are proposed as carriers for 224 Ra, designed for local therapy of disseminated cancers in cavitary regions, such as peritoneal carcinomatosis. Calcium carbonate microparticles were radiolabeled by precipitation of 224 Ra on the particle surface, resulting in high labeling efficiencies for both 224 Ra and daughter 212 Pb and retention of more than 95% of these nuclides for up to 1 week in vitro. The biodistribution after intraperitoneal administration of the 224 Ra-labeled CaCO 3 microparticles in immunodeficient mice revealed that the radioactivity mainly remained in the peritoneal cavity. In addition, the systemic distribution of 224 Ra was found to be strongly dependent on the amount of administered microparticles, with a reduced skeletal uptake of 224 Ra with increasing dose. The results altogether suggest that the 224 Ra-labeled CaCO 3 microparticles have promising properties for use as a localized internal α-therapy of cavitary cancers. © 2018 Oncoinvent AS. Journal of Labelled Compounds and Radiopharmaceuticals Published by John Wiley & Sons, Ltd.

  13. A role for gamma-glutamyl transpeptidase and the amino acid transport system xc- in cystine transport by a human pancreatic duct cell line.

    PubMed Central

    Sweiry, J H; Sastre, J; Viña, J; Elsässer, H P; Mann, G E

    1995-01-01

    1. The roles of the gamma-glutamyl cycle and the anionic amino acid transport system xc- in mediating L-cystine uptake were investigated in cultured human pancreatic duct PaTu 8902 cells. This cell line exhibits morphological features of normal pancreatic duct cells and expresses gamma-glutamyl transpeptidase (gamma-GT, EC 2.3.2.2), an enzyme involved in the metabolism and regulation of intracellular glutathione (GSH). 2. Uptake of L-cystine (10 microM) was linear for up to 10 min, temperature dependent, Na+ independent, saturable (Michaelis-Menten constant (Km), 86 +/- 25 microM; maximal velocity (Vmax), 109 +/- 33 nmol (mg protein)-1 h-1) and reduced by 80-90% by a 50-fold excess concentration of L-glutamate and L-homocysteic acid, but not L-aspartate. These transport properties resemble those described for system xc-, which exchanges cystine for intracellular glutamate. 3. Acivicin, a known inhibitor of gamma-GT, decreased gamma-GT activity from 2.58 +/- 0.96 to 0.97 +/- 0.11 mU (mg protein)-1 and decreased the initial rates of L-cystine and L-glutamine uptake by 41-55%. Anthglutin (1-gamma-L-glutamyl-2-(2-carboxyphenylhyl)hydrazine), a structurally different inhibitor of gamma-GT, also caused a concentration-dependent (0.01-1 mM) decrease in gamma-GT activity and L-cystine uptake. 4. Neither acivicin nor anthglutin inhibited the uptake of L-glutamate, a poor substrate for gamma-GT. 5. In the presence of a 500-fold excess concentration of glutamate, which should abolish entry of cystine via system xc-, the remaining fraction of cystine transport was inhibited by 50% by acivicin, suggesting that transport is, in part, dependent on the activity of gamma-GT. 6. Cystine transport was also 60-80% inhibited by a series of gamma-glutamyl amino acids (5 mM) including gamma-glutamyl-glutamate, gamma-glutamyl-glutamine and gamma-glutamyl-glycine. alpha-Dipeptides inhibited cystine transport by only 6-22%. 7. These findings demonstrate that in human pancreatic duct Pa

  14. Quorum sensing inhibitors from marine bacteria Oceanobacillus sp. XC22919.

    PubMed

    Chen, Xiaochun; Chen, Jianwei; Yan, Yinchun; Chen, Su; Xu, Xuewei; Zhang, Huawei; Wang, Hong

    2018-02-12

    In this study, three active compounds isolated from Oceanobacillus sp. XC22919 were identified as 2-methyl-N-(2'-phenylethyl) butyramide (1), 3-methyl-N-(2'-phenylethyl)-butyramide (2) and benzyl benzoate (3), and were first reported to exhibit the apparent quorum sensing inhibitory activities against C. violaceum 026 and P. aeruginosa. Compounds 1-3 inhibited violacein production of C. violaceum 026 by 10.5-55.7, 11.2-55.7, and 27.2%-95.7%, respectively, and inhibited pyocyanin production of P. aeruginosa by 1.7-50.8, 39.1-90.7, and 57.2%-98.7%, respectively. The azocasein-degrading proteolytic rates of P. aeruginosa were observed by 13.4-31.5, 13.4-28.8, and 11.3%-21.1%, respectively. With respect to elastase, the range of inhibition of activity of compounds 1-3 was 2.1-30.3, 4.2-18.2, and 8.9%-15.7%, respectively. Compounds 1 and 3 also showed a concentration-dependent attenuation in biofilm formation, with the maximum of 50.6% inhibition, and 37.7% inhibition at 100 μg/mL, respectively.

  15. Study of the Thermodynamics of Chromium(III) and Chromium(VI) Binding to Fe3O4 and MnFe2O4 nanoparticles

    PubMed Central

    Luther, Steven; Brogfeld, Nathan; Kim, Jisoo; Parsons, J.G.

    2013-01-01

    Removal of chromium(III) or (VI) from aqueous solution was achieved using Fe3O4, and MnFe2O4 nanomaterials. The nanomaterials were synthesized using a precipitation method and characterized using XRD. The size of the nanomaterials was determined to be 22.4 ± 0.9 nm (Fe3O4) and 15.5 ± 0.5 nm (MnFe2O4). The optimal binding pH for chromium(III) and chromium(VI) were pH 6 and pH 3. Isotherm studies were performed, under light and dark conditions, to determine the capacity of the nanomaterials. The capacities for the light studies with MnFe2O4 and Fe3O4 were determined to be 7.189 and 10.63 mg/g, respectively, for chromium(III). The capacities for the light studies with MnFe2O4 and Fe3O4 were 3.21 and 3.46 mg/g, respectively, for chromium(VI). Under dark reaction conditions the binding of chromium(III) to the MnFe2O4 and Fe3O4 nanomaterials were 5.74 and 15.9 mg/g, respectively. The binding capacity for the binding of chromium(VI) to MnFe2O4 and Fe3O4 under dark reaction conditions were 3.87 and 8.54 mg/g, respectively. The thermodynamics for the reactions showed negative ΔG values, and positive ΔH values. The ΔS values were positive for the binding of chromium(III) and for chromium(VI) binding under dark reaction conditions. The ΔS values for chromium(VI) binding under the light reaction conditions were determined to be negative. PMID:23558081

  16. 49 CFR Appendix C to Part 224 - Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports C Appendix C to Part 224 Transportation Other Regulations... REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK Pt. 224, App. C Appendix C to Part 224—Guidelines for Electronic...

  17. 49 CFR Appendix C to Part 224 - Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports C Appendix C to Part 224 Transportation Other Regulations... REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK Pt. 224, App. C Appendix C to Part 224—Guidelines for Electronic...

  18. 49 CFR Appendix C to Part 224 - Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports C Appendix C to Part 224 Transportation Other Regulations... REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK Pt. 224, App. C Appendix C to Part 224—Guidelines for Electronic...

  19. 49 CFR Appendix C to Part 224 - Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Guidelines for Electronic Submission of Reflectorization Implementation Compliance Reports C Appendix C to Part 224 Transportation Other Regulations... REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK Pt. 224, App. C Appendix C to Part 224—Guidelines for Electronic...

  20. MicroRNA-224 inhibits proliferation and migration of breast cancer cells by down-regulating Fizzled 5 expression.

    PubMed

    Liu, Feng; Liu, Yang; Shen, Jingling; Zhang, Guoqiang; Han, Jiguang

    2016-08-02

    The Wnt/β-catenin signaling is crucial for the proliferation and migration of breast cancer cells. However, the expression of microRNA-224 (miR-224) in the different types of breast cancers and its role in the Wnt/β-catenin signaling and the proliferation and migration of breast cancer cells are poorly understood. In this study, the levels of miR-224 in different types of breast cancer tissues and cell lines were examined by quantitative RT-PCR and the potential targets of miR-224 in the Wnt/β-catenin signaling were investigated. The effects of altered miR-224 expression on the frequency of CD44+CD24- cancer stem-like cells (CSC), proliferation and migration of MCF-7 and MDA-MB-231 cells were examined by flow cytometry, MTT and transwell migration. We found that the levels of miR-224 expression in different types of breast cancer tissues and cell lines were associated inversely with aggressiveness of breast cancers. Enhanced miR-224 expression significantly reduced the fizzled 5-regulated luciferase activity in 293T cells, fizzled 5 expression in MCF-7 and MDA-MB-231 cells, the β-dependent luciferase activity in MCF-7 cells, and the nuclear translocation of β-catenin in MDA-MB-231 cells. miR-224 inhibition significantly increased the percentages of CSC in MCF-7 cells and enhanced proliferation and migration of MCF-7 cells. Enhanced miR-224 expression inhibited proliferation and migration of MDA-MB-231 cells, and the growth of implanted breast cancers in vivo. Induction of Frizzled 5 over-expression mitigated the miR-224-mediated inhibition of breast cancer cell proliferation. Collectively, these data indicated that miR-224 down-regulated the Wnt/β-catenin signaling possibly by binding to Frizzled 5 and inhibited proliferation and migration of breast cancer cells.

  1. Ra‐224 labeling of calcium carbonate microparticles for internal α‐therapy: Preparation, stability, and biodistribution in mice

    PubMed Central

    Westrøm, Sara; Malenge, Marion; Jorstad, Ida Sofie; Napoli, Elisa; Bruland, Øyvind S.; Bønsdorff, Tina B.

    2018-01-01

    Internal therapy with α‐emitters should be well suited for micrometastatic disease. Radium‐224 emits multiple α‐particles through its decay and has a convenient 3.6 days of half‐life. Despite its attractive properties, the use of 224Ra has been limited to bone‐seeking applications because it cannot be stably bound to a targeting molecule. Alternative delivery systems for 224Ra are therefore of considerable interest. In this study, calcium carbonate microparticles are proposed as carriers for 224Ra, designed for local therapy of disseminated cancers in cavitary regions, such as peritoneal carcinomatosis. Calcium carbonate microparticles were radiolabeled by precipitation of 224Ra on the particle surface, resulting in high labeling efficiencies for both 224Ra and daughter 212Pb and retention of more than 95% of these nuclides for up to 1 week in vitro. The biodistribution after intraperitoneal administration of the 224Ra‐labeled CaCO3 microparticles in immunodeficient mice revealed that the radioactivity mainly remained in the peritoneal cavity. In addition, the systemic distribution of 224Ra was found to be strongly dependent on the amount of administered microparticles, with a reduced skeletal uptake of 224Ra with increasing dose. The results altogether suggest that the 224Ra‐labeled CaCO3 microparticles have promising properties for use as a localized internal α‐therapy of cavitary cancers. PMID:29380410

  2. 49 CFR 224.1 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK General § 224.1 Purpose and scope... rolling stock so as to increase its detectability by motor vehicle operators at night and under conditions of poor visibility. (b) In order to achieve cost-effective mitigation of collision risk at highway...

  3. A Deep Extragalactic Survey with the ART-XC Telescope of the Spectrum-RG Observatory: Simulations and Expected Results

    NASA Astrophysics Data System (ADS)

    Mereminskiy, I. A.; Filippova, E. V.; Burenin, R. A.; Sazonov, S. Yu.; Pavlinsky, M. N.; Tkachenko, A. Yu.; Lapshov, I. Yu.; Shtykovskiy, A. E.; Krivonos, R. A.

    2018-02-01

    To choose the best strategy for conducting a deep extragalactic survey with the ART-XC X-ray telescope onboard the Spectrum-Röntgen-Gamma (SRG) observatory and to estimate the expected results, we have simulated the observations of a 1.1° × 1.1° field in the 5-11 and 8-24 keV energy bands. For this purpose, we have constructed a model of the active galactic nuclei (AGN) population that reflects the properties of the X-ray emission from such objects. The photons that "arrived" from these sources were passed through a numerical model of the telescope, while the resulting data were processed with the standard ART-XC data processing pipeline. We show that several hundred AGNs at redshifts up to z ≈ 3 will be detected in such a survey over 1.2 Ms of observations with the expected charged particle background levels. Among them there will be heavily obscured AGNs, which will allow a more accurate estimate of the fraction of such objects in the total population to be made. Source confusion is expected at fluxes below 2 × 10-14 erg s-1 cm-2 (5-11 keV). Since this value can exceed the source detection threshold in a deep survey at low particle background levels, it may turn out to be more interesting to conduct a survey of larger area (several square degrees) but smaller depth, obtaining a sample of approximately four hundred bright AGNs as a result.

  4. 25 CFR 224.42 - How does the Paperwork Reduction Act affect these regulations?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How does the Paperwork Reduction Act affect these regulations? 224.42 Section 224.42 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  5. 25 CFR 224.108 - May tribes offer a resolution of a petitioner's claim?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false May tribes offer a resolution of a petitioner's claim? 224.108 Section 224.108 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  6. 25 CFR 224.42 - How does the Paperwork Reduction Act affect these regulations?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How does the Paperwork Reduction Act affect these regulations? 224.42 Section 224.42 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  7. 25 CFR 224.108 - May tribes offer a resolution of a petitioner's claim?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false May tribes offer a resolution of a petitioner's claim? 224.108 Section 224.108 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  8. Discriminative stimulus effects of the imidazoline I2 receptor ligands BU224 and phenyzoline in rats.

    PubMed

    Qiu, Yanyan; Zhang, Yanan; Li, Jun-Xu

    2015-02-15

    Although imidazoline I2 receptor ligands have been used as discriminative stimuli, the role of efficacy of I2 receptor ligands as a critical determinant in drug discrimination has not been explored. This study characterized the discriminative stimulus effects of selective imidazoline I2 receptor ligands BU224 (a low-efficacy I2 receptor ligand) and phenyzoline (a higher efficacy I2 receptor ligand) in rats. Two groups of male Sprague-Dawley rats were trained to discriminate 5.6mg/kg BU224 or 32mg/kg phenyzoline (i.p.) from their vehicle in a two-lever food-reinforced drug discrimination procedure, respectively. All rats acquired the discriminations after an average of 18 (BU224) and 56 (phenyzoline) training sessions, respectively. BU224 and phenyzoline completely substituted for one another symmetrically. Several I2 receptor ligands (tracizoline, CR4056, RS45041, and idazoxan) all occasioned>80% drug-associated lever responding in both discriminations. The I2 receptor ligand 2-BFI and a monoamine oxidase inhibitor harmane occasioned>80% drug-associated lever responding in rats discriminating BU224. Other drugs that occasioned partial or less substitution to BU224 cue included clonidine, methamphetamine, ketamine, morphine, methadone and agmatine. Clonidine, methamphetamine and morphine also only produced partial substitution to phenyzoline cue. Naltrexone, dopamine D2 receptor antagonist haloperidol and serotonin (5-HT)2A receptor antagonist MDL100907 failed to alter the discriminative stimulus effects of BU224 or phenyzoline. Combined, these results are the first to demonstrate that BU224 and phenyzoline can serve as discriminative stimuli and that the low-efficacy I2 receptor ligand BU224 shares similar discriminative stimulus effects with higher-efficacy I2 receptor ligands such as phenyzoline and 2-BFI. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Thomas-Reiche-Khun populations in X-CH 3 and X-C 2H 5 series of molecules

    NASA Astrophysics Data System (ADS)

    Zitto, M. E.; Caputo, M. C.; Ferraro, M. B.; Lazzeretti, P.

    2000-09-01

    Calculations of nuclear electric shieldings, equivalent to dipole moment geometric derivatives, and related to atomic polar tensors, are presented for X-CH 3 and X-C 2H 5 molecules with X=NH 2, OH and F. The electric shielding tensors satisfy a constraint for the electrostatic equilibrium, i.e., the mixed length-acceleration Thomas-Reiche-Khun sum rule, which gives important indications on the reliability of theoretical predictions of IR intensities and leads to the definition of atomic populations. Numerical evidence was found for the additivity and transferability of atomic populations, within the X-substituted alkane series.

  10. 25 CFR 224.154 - What must a notice of intent to reassume include?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must a notice of intent to reassume include? 224.154 Section 224.154 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  11. 25 CFR 224.154 - What must a notice of intent to reassume include?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What must a notice of intent to reassume include? 224.154 Section 224.154 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  12. 25 CFR 224.40 - How does the Act or a TERA affect the Secretary's trust responsibility?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How does the Act or a TERA affect the Secretary's trust responsibility? 224.40 Section 224.40 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.40...

  13. Synergistic increase of oxygen reduction favourable Fe-N coordination structures in a ternary hybrid of carbon nanospheres/carbon nanotubes/graphene sheets.

    PubMed

    Zhang, Shiming; Liu, Bin; Chen, Shengli

    2013-11-14

    A Fe/N co-doped ternary nanocarbon hybrid, with uniform bamboo-like carbon nanotubes (CNTs) in situ grown on/between the single/few-layer graphene sheets interspaced by carbon nanosphere aggregates, was prepared through a one-pot heat treatment of a precursor mixture containing graphene oxide, Vulcan XC-72 carbon nanospheres, nitrogen rich melamine and small amounts of Fe ions. Physical characterization including electron microscopic images, N2 adsorption-desorption isotherms, pore size distribution, XPS, XRD, Mössbauer spectra, and EDX revealed that the 0-D/1-D/2-D ternary hybrid architecture not only offered an optimized morphology for high dispersion of each nanocarbon moiety, while the carbon nanosphere interspaced graphene sheets have provided a platform for efficient reaction between Fe ions and melamine molecules, resulting in uniform nucleation and growth of CNTs and formation of high density Fe-N coordination assemblies that have been believed to be the active centers for the oxygen reduction reaction (ORR) in carbon-based nonprecious metal electrocatalysts. In the absence of graphene oxides or carbon nanospheres, a similar heat treatment was found to result in large amounts of elemental Fe and Fe carbides and entangled CNTs with wide diameter distributions. As a result, the ternary Fe/N-doped nanocarbon hybrid exhibits ORR activity much higher than the Fe-N doped single or binary nanocarbon materials prepared under similar heat treatment conditions, and approaching that of the state-of-the-art carbon-supported platinum catalyst (Pt/C) in acidic media, as well as superior stability and methanol tolerance to Pt/C.

  14. 29 CFR 1952.224 - Final approval determination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Federal program; to submit plan supplements in accordance with 29 CFR part 1953; to allocate sufficient..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Tennessee § 1952.224... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall (CA 74-406), and was...

  15. 29 CFR 1952.224 - Final approval determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Federal program; to submit plan supplements in accordance with 29 CFR part 1953; to allocate sufficient..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Tennessee § 1952.224... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall (CA 74-406), and was...

  16. 76 FR 59481 - Ninth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... Control Systems (Update to DO-230B): Agenda October 20, 2011 Welcome/Introductions/Administrative Remarks... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems. SUMMARY...

  17. 76 FR 50811 - Eighth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... Control Systems (Update to DO-230B): Agenda September 15, 2011 Welcome/Introductions/Administrative... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems. SUMMARY...

  18. 25 CFR 1000.224 - How can a Tribe/Consortium expedite the review of a regulation waiver request?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... regulation waiver request? 1000.224 Section 1000.224 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.224 How can a...

  19. 31 CFR 224.3 - When may a surety corporation provide a bond without appointing a process agent?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... a bond without appointing a process agent? 224.3 Section 224.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.3 When may a surety corporation...

  20. 31 CFR 224.3 - When may a surety corporation provide a bond without appointing a process agent?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... a bond without appointing a process agent? 224.3 Section 224.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.3 When may a surety corporation...

  1. 76 FR 38742 - Seventh Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... Control Systems (Update to DO-230B): Agenda July 15, 2011 Welcome/Introductions/Administrative Remarks... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to...

  2. 31 CFR 224.3 - When may a surety corporation provide a bond without appointing a process agent?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.3 When may a surety corporation provide a bond without appointing a process agent? A surety corporation may provide a bond without... a bond without appointing a process agent? 224.3 Section 224.3 Money and Finance: Treasury...

  3. Antipneumococcal activity of DW-224a, a new quinolone, compared to those of eight other agents.

    PubMed

    Kosowska-Shick, Klaudia; Credito, Kim; Pankuch, Glenn A; Lin, Gengrong; Bozdogan, Bülent; McGhee, Pamela; Dewasse, Bonifacio; Choi, Dong-Rack; Ryu, Jei Man; Appelbaum, Peter C

    2006-06-01

    DW-224a is a new broad-spectrum quinolone with excellent antipneumococcal activity. Agar dilution MIC was used to test the activity of DW-224a compared to those of penicillin, ciprofloxacin, levofloxacin, gatifloxacin, moxifloxacin, gemifloxacin, amoxicillin-clavulanate, cefuroxime, and azithromycin against 353 quinolone-susceptible pneumococci. The MICs of 29 quinolone-resistant pneumococci with defined quinolone resistance mechanisms against seven quinolones and an efflux mechanism were also tested. DW-224a was the most potent quinolone against quinolone-susceptible pneumococci (MIC(50), 0.016 microg/ml; MIC(90), 0.03 microg/ml), followed by gemifloxacin, moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin. beta-Lactam MICs rose with those of penicillin G, and azithromycin resistance was seen mainly in strains with raised penicillin G MICs. Against the 29 quinolone-resistant strains, DW-224a had the lowest MICs (0.06 to 1 microg/ml) compared to those of gemifloxacin, clinafloxacin, moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin. DW-224a at 2x MIC was bactericidal after 24 h against eight of nine strains tested. Other quinolones gave similar kill kinetics relative to higher MICs. Serial passages of nine strains in the presence of sub-MIC concentrations of DW-224a, moxifloxacin, levofloxacin, ciprofloxacin, gatifloxacin, gemifloxacin, amoxicillin-clavulanate, cefuroxime, and azithromycin were performed. DW-224a yielded resistant clones similar to moxifloxacin and gemifloxacin but also yielded lower MICs. Azithromycin selected resistant clones in three of the five parents tested. Amoxicillin-clavulanate and cefuroxime did not yield resistant clones after 50 days.

  4. 34 CFR 300.224 - Requirements for establishing eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... must provide for the education of children with disabilities in the least restrictive environment, as... EDUCATION OF CHILDREN WITH DISABILITIES Local Educational Agency Eligibility § 300.224 Requirements for... this section must— (1) Adopt policies and procedures that are consistent with the State's policies and...

  5. Transient electronic anisotropy in overdoped NaF e1 -xC oxAs superconductors

    NASA Astrophysics Data System (ADS)

    Liu, Shenghua; Zhang, Chunfeng; Deng, Qiang; Wen, Hai-hu; Li, Jian-xin; Chia, Elbert E. M.; Wang, Xiaoyong; Xiao, Min

    2018-01-01

    By combining polarized pump-probe spectroscopic and Laue x-ray diffraction measurements, we have observed nonequivalent transient optical responses with the probe beam polarized along the x and y axes in overdoped NaF e1 -xC oxAs superconductors. Such transient anisotropic behavior has been uncovered in the tetragonal phase with the doping level and temperature range far from the borders of static nematic phases. The measured transient anisotropy can be well explained as a result of nematic fluctuation driven by an orbital order with energy splitting of the dx z- and dy z-dominant bands. In addition, the doping level dependence and the pressure effect of the crossover temperature show significant differences between the transient nematic fluctuation and static nematic phase, implying spin and orbital orders may play different roles in static and transient nematic behaviors.

  6. 25 CFR 224.66 - How may a tribe reduce the scope of the TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 224.66 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for Obtaining Tribal Energy Resource Agreements Tera Requirements § 224.66 How may a tribe reduce...

  7. 77 FR 71474 - Seventeenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the seventeenth meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  8. 78 FR 7850 - Nineteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the nineteenth meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  9. 77 FR 2343 - Eleventh Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the eleventh meeting of RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held...

  10. 77 FR 25525 - Thirteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... Committee 224, Airport Security Access Control Systems. AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the thirteenth meeting of RTCA Special Committee 224, Airport Security Access Control Systems DATES: The meeting will be...

  11. 77 FR 15448 - Twelfth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the twelfth meeting of RTCA Special Committee 224, Airport Security Access Control Systems DATES: The meeting will be...

  12. 36 CFR 223.224 - Performance bonds and security.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Performance bonds and... AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST BOTANICAL PRODUCTS Special Forest Products Contract and Permit Conditions and Provisions § 223.224 Performance bonds...

  13. 48 CFR 52.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Privacy Act Notification....224-1 Privacy Act Notification. As prescribed in 24.104, insert the following clause in solicitations... required to accomplish an agency function: Privacy Act Notification (APR 1984) The Contractor will be...

  14. 48 CFR 52.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Privacy Act Notification....224-1 Privacy Act Notification. As prescribed in 24.104, insert the following clause in solicitations... required to accomplish an agency function: Privacy Act Notification (APR 1984) The Contractor will be...

  15. 48 CFR 52.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Privacy Act Notification....224-1 Privacy Act Notification. As prescribed in 24.104, insert the following clause in solicitations... required to accomplish an agency function: Privacy Act Notification (APR 1984) The Contractor will be...

  16. 48 CFR 52.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Privacy Act Notification....224-1 Privacy Act Notification. As prescribed in 24.104, insert the following clause in solicitations... required to accomplish an agency function: Privacy Act Notification (APR 1984) The Contractor will be...

  17. 48 CFR 52.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Privacy Act Notification....224-1 Privacy Act Notification. As prescribed in 24.104, insert the following clause in solicitations... required to accomplish an agency function: Privacy Act Notification (APR 1984) The Contractor will be...

  18. 25 CFR 224.111 - When may a petitioner file a petition with the Secretary?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false When may a petitioner file a petition with the Secretary? 224.111 Section 224.111 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  19. 25 CFR 224.157 - How must the Secretary proceed after receiving the tribe's response?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How must the Secretary proceed after receiving the tribe's response? 224.157 Section 224.157 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  20. 25 CFR 224.181 - Who may appeal Departmental decisions or inaction under this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Who may appeal Departmental decisions or inaction under this part? 224.181 Section 224.181 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  1. 25 CFR 224.181 - Who may appeal Departmental decisions or inaction under this part?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Who may appeal Departmental decisions or inaction under this part? 224.181 Section 224.181 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  2. 25 CFR 224.157 - How must the Secretary proceed after receiving the tribe's response?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How must the Secretary proceed after receiving the tribe's response? 224.157 Section 224.157 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  3. 25 CFR 224.132 - How does the Director conduct a periodic review and evaluation?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How does the Director conduct a periodic review and evaluation? 224.132 Section 224.132 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  4. 25 CFR 224.111 - When may a petitioner file a petition with the Secretary?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When may a petitioner file a petition with the Secretary? 224.111 Section 224.111 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  5. 25 CFR 224.112 - What must the Director do upon receipt of a petition?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must the Director do upon receipt of a petition? 224.112 Section 224.112 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  6. 25 CFR 224.57 - What must the Director do upon receipt of an application?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What must the Director do upon receipt of an application? 224.57 Section 224.57 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  7. 25 CFR 224.112 - What must the Director do upon receipt of a petition?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What must the Director do upon receipt of a petition? 224.112 Section 224.112 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT...

  8. Antipneumococcal Activity of DW-224a, a New Quinolone, Compared to Those of Eight Other Agents

    PubMed Central

    Kosowska-Shick, Klaudia; Credito, Kim; Pankuch, Glenn A.; Lin, Gengrong; Bozdogan, Bülent; McGhee, Pamela; Dewasse, Bonifacio; Choi, Dong-Rack; Ryu, Jei Man; Appelbaum, Peter C.

    2006-01-01

    DW-224a is a new broad-spectrum quinolone with excellent antipneumococcal activity. Agar dilution MIC was used to test the activity of DW-224a compared to those of penicillin, ciprofloxacin, levofloxacin, gatifloxacin, moxifloxacin, gemifloxacin, amoxicillin-clavulanate, cefuroxime, and azithromycin against 353 quinolone-susceptible pneumococci. The MICs of 29 quinolone-resistant pneumococci with defined quinolone resistance mechanisms against seven quinolones and an efflux mechanism were also tested. DW-224a was the most potent quinolone against quinolone-susceptible pneumococci (MIC50, 0.016 μg/ml; MIC90, 0.03 μg/ml), followed by gemifloxacin, moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin. β-Lactam MICs rose with those of penicillin G, and azithromycin resistance was seen mainly in strains with raised penicillin G MICs. Against the 29 quinolone-resistant strains, DW-224a had the lowest MICs (0.06 to 1 μg/ml) compared to those of gemifloxacin, clinafloxacin, moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin. DW-224a at 2× MIC was bactericidal after 24 h against eight of nine strains tested. Other quinolones gave similar kill kinetics relative to higher MICs. Serial passages of nine strains in the presence of sub-MIC concentrations of DW-224a, moxifloxacin, levofloxacin, ciprofloxacin, gatifloxacin, gemifloxacin, amoxicillin-clavulanate, cefuroxime, and azithromycin were performed. DW-224a yielded resistant clones similar to moxifloxacin and gemifloxacin but also yielded lower MICs. Azithromycin selected resistant clones in three of the five parents tested. Amoxicillin-clavulanate and cefuroxime did not yield resistant clones after 50 days. PMID:16723567

  9. The study of structure in 224-234 thorium nuclei within the framework IBM

    NASA Astrophysics Data System (ADS)

    Lee, Su Youn; Lee, Young Jun; Lee, J. H.

    2017-09-01

    An investigation has been made of the behaviour of nuclear structure as a function of an increase in neutron number from 224Th to 234Th. Thorium of mass number 234 is a typical rotor nucleus that can be explained by the SU(3) limit of the interacting boson model(IBM) in the algebraic nuclear model. Furthermore, 224-232Th lie on the path of the symmetry-breaking phase transition. Moreover, the nuclear structure of 224Th can be explained using X(5) symmetry. However, as 226-230Th nuclei are not fully symmetrical nuclei, they can be represented by adding a perturbed term to express symmetry breaking. Through the following three calculation steps, we identified the tendency of change in nuclear structure. Firstly, the structure of 232Th is described using the matrix elements of the Hamiltonian and the electric quadrupole operator between basis states of the SU(3) limit in IBM. Secondly, the low-lying energy levels and E2 transition ratios corresponding to the observable physical values are calculated by adding a perturbed term with the first-order Casimir operator of the U(5) limit to the SU(3) Hamiltonian in IBM. We compared the results with experimental data of 224-234Th. Lastly, the potential of the Bohr Hamiltonian is represented by a harmonic oscillator, as a result of which the structure of 224-234Th could be expressed in closed form by an approximate separation of variables. The results of these theoretical predictions clarify nuclear structure changes in Thorium nuclei over mass numbers of practical significance.

  10. 50 CFR 224.104 - Special requirements for fishing activities to protect endangered sea turtles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... activities to protect endangered sea turtles. 224.104 Section 224.104 Wildlife and Fisheries NATIONAL MARINE... endangered sea turtles. (a) Shrimp fishermen in the southeastern United States and the Gulf of Mexico who comply with rules for threatened sea turtles specified in § 223.206 of this chapter will not be subject...

  11. 50 CFR 224.104 - Special requirements for fishing activities to protect endangered sea turtles.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... activities to protect endangered sea turtles. 224.104 Section 224.104 Wildlife and Fisheries NATIONAL MARINE... endangered sea turtles. (a) Shrimp fishermen in the southeastern United States and the Gulf of Mexico who comply with rules for threatened sea turtles specified in § 223.206 of this chapter will not be subject...

  12. 31 CFR 224.6 - Where can I find a sample power of attorney form?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Where can I find a sample power of attorney form? 224.6 Section 224.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF...

  13. 31 CFR 224.6 - Where can I find a sample power of attorney form?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false Where can I find a sample power of attorney form? 224.6 Section 224.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF...

  14. 31 CFR 224.6 - Where can I find a sample power of attorney form?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false Where can I find a sample power of attorney form? 224.6 Section 224.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF...

  15. Polarization effects in the elastic scattering of low-energy electrons by XH{sub 4} (X=C, Si, Ge, Sn, Pb)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bettega, M.H.F.; Varella, M.T.N. do; Lima, M.A.P.

    2003-07-01

    We report integral and differential cross sections for elastic scattering of electrons by XH{sub 4} (X=C, Si, Ge, Sn, Pb) molecules for energies between 3 and 10 eV. We use the Schwinger multichannel method with pseudopotentials [Bettega et al., Phys. Rev. A 47, 1111 (1993)] at the static-exchange and static-exchange plus polarization approximations. We compare our results with available theoretical and experimental results and find very good agreement. In particular, our results show Ramsauer-Towsend minima for all XH{sub 4} molecules.

  16. 48 CFR 1452.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Privacy Act Notification... Privacy Act Notification. (a) As prescribed in 1424.104, the clause at FAR 52.224-1, Privacy Act... the clause to read “Privacy Act Notification (JUL 1996) (Deviation)”; and (2) Adding the following...

  17. 48 CFR 1452.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Privacy Act Notification... Privacy Act Notification. (a) As prescribed in 1424.104, the clause at FAR 52.224-1, Privacy Act... the clause to read “Privacy Act Notification (JUL 1996) (Deviation)”; and (2) Adding the following...

  18. 48 CFR 1452.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Privacy Act Notification... Privacy Act Notification. (a) As prescribed in 1424.104, the clause at FAR 52.224-1, Privacy Act... the clause to read “Privacy Act Notification (JUL 1996) (Deviation)”; and (2) Adding the following...

  19. 48 CFR 1452.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Privacy Act Notification... Privacy Act Notification. (a) As prescribed in 1424.104, the clause at FAR 52.224-1, Privacy Act... the clause to read “Privacy Act Notification (JUL 1996) (Deviation)”; and (2) Adding the following...

  20. 48 CFR 1452.224-1 - Privacy Act Notification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Privacy Act Notification... Privacy Act Notification. (a) As prescribed in 1424.104, the clause at FAR 52.224-1, Privacy Act... the clause to read “Privacy Act Notification (JUL 1996) (Deviation)”; and (2) Adding the following...

  1. 25 CFR 224.62 - May a final proposed TERA differ from the original proposed TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... proposed TERA? 224.62 Section 224.62 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for Obtaining Tribal Energy Resource Agreements Application Consultation Meeting...

  2. MiR224-3p inhibits hypoxia-induced autophagy by targeting autophagy-related genes in human glioblastoma cells.

    PubMed

    Guo, Xing; Xue, Hao; Guo, Xiaofan; Gao, Xiao; Xu, Shugang; Yan, Shaofeng; Han, Xiao; Li, Tong; Shen, Jie; Li, Gang

    2015-12-08

    Human glioblastoma multiforme (GBM) is a malignant solid tumor characterized by severe hypoxia. Autophagy plays a protective role in cancer cells under hypoxia. However, the microRNA (miRNA)-related molecular mechanisms underlying hypoxia-reduced autophagy remain poorly understood in GBM. In this study, we performed a miRNA microarray analysis on GBM cells and found that numerous miRNAs were differentially expressed under hypoxic conditions. Further research showed that miR224-3p, one of the significantly down-regulated miRNAs, was involved in regulating hypoxia-induced autophagy in GBM cells. Overexpression of miR224-3p abolished hypoxia-induced autophagy, whereas knocking down endogenous miR224-3p increased autophagic activity under normoxia. In addition, we demonstrated that miR224-3p inhibited autophagy by directly suppressing the expression of two autophagy-related genes (ATGs), ATG5 and FAK family-interacting protein of 200 kDa (FIP200). Furthermore, in vitro, miR224-3p attenuated cell proliferation and promoted hypoxia-induced apoptosis, and in vivo, overexpression of miR224-3p inhibited tumorigenesis of GBM cells. Collectively, our study identified a novel hypoxia-down-regulated miRNA, miR224-3p, as a key modulator of autophagy by inhibiting ATGs in GBM cells.

  3. 25 CFR 224.59 - How will the Director use the results of the application consultation meeting?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF... information provided through §§ 224.53 and 224.63 to determine the energy resource development capacity of the...

  4. Measurements of the absolute branching fractions of B+→Xc c ¯K+ and B+→D¯(*)0π+ at Belle

    NASA Astrophysics Data System (ADS)

    Kato, Y.; Iijima, T.; Adachi, I.; Aihara, H.; Al Said, S.; Asner, D. M.; Aulchenko, V.; Aushev, T.; Ayad, R.; Babu, V.; Badhrees, I.; Bakich, A. M.; Bansal, V.; Barberio, E.; Behera, P.; Bhardwaj, V.; Bhuyan, B.; Biswal, J.; Bozek, A.; Bračko, M.; Browder, T. E.; Červenkov, D.; Chang, P.; Cheaib, R.; Chekelian, V.; Chen, A.; Cheon, B. G.; Chilikin, K.; Cho, K.; Choi, S.-K.; Choi, Y.; Cinabro, D.; Czank, T.; Dash, N.; Di Carlo, S.; Doležal, Z.; Drásal, Z.; Dutta, D.; Eidelman, S.; Epifanov, D.; Fast, J. E.; Ferber, T.; Fulsom, B. G.; Gaur, V.; Gabyshev, N.; Garmash, A.; Gelb, M.; Goldenzweig, P.; Greenwald, D.; Guido, E.; Haba, J.; Hayasaka, K.; Hayashii, H.; Hedges, M. T.; Hirose, S.; Hou, W.-S.; Inami, K.; Inguglia, G.; Ishikawa, A.; Itoh, R.; Iwasaki, M.; Iwasaki, Y.; Jacobs, W. W.; Jaegle, I.; Jeon, H. B.; Jin, Y.; Joo, K. K.; Julius, T.; Kaliyar, A. B.; Kang, K. H.; Karyan, G.; Kawasaki, T.; Kichimi, H.; Kiesling, C.; Kim, D. Y.; Kim, J. B.; Kim, S. H.; Kim, Y. J.; Kinoshita, K.; Kodyš, P.; Korpar, S.; Kotchetkov, D.; Križan, P.; Kroeger, R.; Krokovny, P.; Kuhr, T.; Kulasiri, R.; Kuzmin, A.; Kwon, Y.-J.; Lange, J. S.; Lee, I. S.; Li, C. H.; Li, L.; Li Gioi, L.; Libby, J.; Liventsev, D.; Lubej, M.; Luo, T.; Masuda, M.; Matsuda, T.; Merola, M.; Miyabayashi, K.; Miyata, H.; Mizuk, R.; Mohanty, G. B.; Moon, H. K.; Mori, T.; Mussa, R.; Nakano, E.; Nakao, M.; Nanut, T.; Nath, K. J.; Natkaniec, Z.; Nayak, M.; Niiyama, M.; Nisar, N. K.; Nishida, S.; Ogawa, S.; Okuno, S.; Ono, H.; Pakhlov, P.; Pakhlova, G.; Pal, B.; Park, C.-S.; Park, C. W.; Park, H.; Paul, S.; Pedlar, T. K.; Pestotnik, R.; Piilonen, L. E.; Ritter, M.; Rostomyan, A.; Sakai, Y.; Salehi, M.; Sandilya, S.; Sato, Y.; Savinov, V.; Schneider, O.; Schnell, G.; Schwanda, C.; Schwartz, A. J.; Seino, Y.; Senyo, K.; Sevior, M. E.; Shebalin, V.; Shen, C. P.; Shibata, T.-A.; Shiu, J.-G.; Simon, F.; Sokolov, A.; Solovieva, E.; Starič, M.; Strube, J. F.; Sumihama, M.; Sumisawa, K.; Sumiyoshi, T.; Takizawa, M.; Tamponi, U.; Tanida, K.; Tenchini, F.; Trabelsi, K.; Uchida, M.; Uehara, S.; Uglov, T.; Unno, Y.; Uno, S.; Urquijo, P.; Usov, Y.; Van Hulse, C.; Varner, G.; Varvell, K. E.; Vorobyev, V.; Wang, C. H.; Wang, M.-Z.; Wang, P.; Watanabe, M.; Watanuki, S.; Widmann, E.; Won, E.; Yamashita, Y.; Ye, H.; Yelton, J.; Yuan, C. Z.; Yusa, Y.; Zhang, Z. P.; Zhilich, V.; Zhukova, V.; Zhulanov, V.; Zupanc, A.; Belle Collaboration

    2018-01-01

    We present the measurement of the absolute branching fractions of B+→Xc c ¯K+ and B+→D¯ (*)0π+ decays, using a data sample of 772 ×106 B B ¯ pairs collected at the ϒ (4 S ) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. Here, Xc c ¯ denotes ηc, J /ψ , χc 0, χc 1, ηc(2 S ), ψ (2 S ), ψ (3770 ), X (3872 ), and X (3915 ). We do not observe significant signals for X (3872 ) or X (3915 ) and set the 90% confidence level upper limits at B (B+→X (3872 )K+)<2.6 ×10-4 and B (B+→X (3915 )K+)<2.8 ×10-4 . These represent the most stringent upper limit for B (B+→X (3872 )K+) to date and the first limit for B (B+→X (3915 )K+). The measured branching fractions for ηc and ηc(2 S ) are the most precise to date, B (B+→ηcK+)=(12.0 ±0.8 ±0.7 )×10-4 and B (B+→ηc(2 S )K+)=(4.8 ±1.1 ±0.3 )×10-4 , where the first and second uncertainties are statistical and systematic, respectively.

  5. Tuning the Magnetic Properties and Structural Stabilities of the 2-17-3 Magnets Sm 2Fe 17X 3 (X=C, N) by Substituting La or Ce for Sm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pandey, Tribhuwan; Du, Mao-Hua; Parker, David S.

    Designing a permanent magnet with reduced critical rare-earth content is of paramount importance in the development of cost-effective modern technologies. By performing comprehensive first-principles calculations, we investigate the potential avenues for reducing the critical rare-earth content in Sm 2Fe 17N 3 and Sm 2Fe 17C 3 by making a La or Ce substitution for Sm. The calculated magnetic properties of base compounds are in good agreement with the previous low-temperature (4.2-K) experimental measurements, and they show a large axial anisotropy. Although La or Ce substitution results in a slight reduction of magnetic anisotropy, the magnetic moments of Fe atoms mostlymore » remain unchanged. Specifically, large axial anisotropies of 7.2 and 4.1 MJ/m 3 are obtained for SmCeFe 17N 3 and SmLaFe 17N 3, respectively. These values of anisotropies are comparable to the state-of-the-art permanent magnet Nd 2Fe 14B. The foremost limitation of Sm 2Fe 17X 3 magnets for practical application is the formation nitrogen or carbon vacancies at high temperatures. By calculating the N- (C)- vacancy formation energy, we show that La or Ce substitution enhances the vacancy formation energy. Here, this enhanced vacancy formation energy will likely improve the thermodynamic stability of these alloys at high temperatures. Therefore, La- or Ce-substituted Sm 2Fe 17C 3 and Sm 2Fe 17N 3 compounds are promising candidates for high-performance permanent magnets with substantially reduced rare-earth content.« less

  6. Tuning the Magnetic Properties and Structural Stabilities of the 2-17-3 Magnets Sm 2Fe 17X 3 (X=C, N) by Substituting La or Ce for Sm

    DOE PAGES

    Pandey, Tribhuwan; Du, Mao-Hua; Parker, David S.

    2018-03-05

    Designing a permanent magnet with reduced critical rare-earth content is of paramount importance in the development of cost-effective modern technologies. By performing comprehensive first-principles calculations, we investigate the potential avenues for reducing the critical rare-earth content in Sm 2Fe 17N 3 and Sm 2Fe 17C 3 by making a La or Ce substitution for Sm. The calculated magnetic properties of base compounds are in good agreement with the previous low-temperature (4.2-K) experimental measurements, and they show a large axial anisotropy. Although La or Ce substitution results in a slight reduction of magnetic anisotropy, the magnetic moments of Fe atoms mostlymore » remain unchanged. Specifically, large axial anisotropies of 7.2 and 4.1 MJ/m 3 are obtained for SmCeFe 17N 3 and SmLaFe 17N 3, respectively. These values of anisotropies are comparable to the state-of-the-art permanent magnet Nd 2Fe 14B. The foremost limitation of Sm 2Fe 17X 3 magnets for practical application is the formation nitrogen or carbon vacancies at high temperatures. By calculating the N- (C)- vacancy formation energy, we show that La or Ce substitution enhances the vacancy formation energy. Here, this enhanced vacancy formation energy will likely improve the thermodynamic stability of these alloys at high temperatures. Therefore, La- or Ce-substituted Sm 2Fe 17C 3 and Sm 2Fe 17N 3 compounds are promising candidates for high-performance permanent magnets with substantially reduced rare-earth content.« less

  7. 78 FR 31627 - Twenty-Second Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the twenty-second meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  8. 78 FR 22025 - Twenty First Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the twenty first meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  9. 22 CFR 224.38 - Reconsideration of initial decision.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CIVIL REMEDIES ACT § 224.38 Reconsideration of initial decision. (a) Except as provided in paragraph (d... days of receipt of the initial decision. If service was made by mail, receipt will be presumed to be five days from the date of mailing in the absence of contrary proof. (b) Every such motion must set...

  10. 12 CFR 224.1 - Authority, purpose, and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SYSTEM BORROWERS OF SECURITIES CREDIT (REGULATION X) § 224.1 Authority, purpose, and scope. (a) Authority and purpose. Regulation X (this part) is issued by the Board of Governors of the Federal Reserve... who is exempt by Order upon terms and conditions set by the Board. [Reg. X, 48 FR 56572, Dec. 22, 1983...

  11. 12 CFR 224.1 - Authority, purpose, and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SYSTEM BORROWERS OF SECURITIES CREDIT (REGULATION X) § 224.1 Authority, purpose, and scope. (a) Authority and purpose. Regulation X (this part) is issued by the Board of Governors of the Federal Reserve... who is exempt by Order upon terms and conditions set by the Board. [Reg. X, 48 FR 56572, Dec. 22, 1983...

  12. 25 CFR 224.133 - What must the Director do after a periodic review and evaluation?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must the Director do after a periodic review and evaluation? 224.133 Section 224.133 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  13. 25 CFR 224.134 - How often must the Director conduct a periodic review and evaluation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How often must the Director conduct a periodic review and evaluation? 224.134 Section 224.134 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  14. 25 CFR 224.134 - How often must the Director conduct a periodic review and evaluation?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How often must the Director conduct a periodic review and evaluation? 224.134 Section 224.134 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  15. 25 CFR 224.114 - How may the tribe address a petition in its written response?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How may the tribe address a petition in its written response? 224.114 Section 224.114 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  16. 25 CFR 224.133 - What must the Director do after a periodic review and evaluation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What must the Director do after a periodic review and evaluation? 224.133 Section 224.133 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  17. 25 CFR 224.158 - What must the Secretary include in a written notice of reassumption?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What must the Secretary include in a written notice of reassumption? 224.158 Section 224.158 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  18. 25 CFR 224.158 - What must the Secretary include in a written notice of reassumption?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must the Secretary include in a written notice of reassumption? 224.158 Section 224.158 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  19. 25 CFR 224.114 - How may the tribe address a petition in its written response?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How may the tribe address a petition in its written response? 224.114 Section 224.114 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  20. 25 CFR 224.74 - When must the Secretary approve or disapprove a final proposed TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When must the Secretary approve or disapprove a final proposed TERA? 224.74 Section 224.74 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  1. 25 CFR 224.62 - May a final proposed TERA differ from the original proposed TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false May a final proposed TERA differ from the original proposed TERA? 224.62 Section 224.62 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  2. Identification of biomarkers for the antiangiogenic and antitumour activity of the superoxide dismutase 1 (SOD1) inhibitor tetrathiomolybdate (ATN-224)

    PubMed Central

    Doñate, F; Juarez, J C; Burnett, M E; Manuia, M M; Guan, X; Shaw, D E; Smith, E L P; Timucin, C; Braunstein, M J; Batuman, O A; Mazar, A P

    2008-01-01

    Tetrathiomolybdate (choline salt; ATN-224), a specific, high-affinity copper binder, is currently being evaluated in several phase II cancer trials. ATN-224 inhibits CuZn superoxide dismutase 1 (SOD1) leading to antiangiogenic and antitumour effects. The pharmacodynamics of tetrathiomolybdate has been followed by tracking ceruloplasmin (Cp), a biomarker for systemic copper. However, at least in mice, the inhibition of angiogenesis occurs before a measurable decrease in systemic copper is observed. Thus, the identification and characterisation of other biomarkers to follow the activity of ATN-224 in the clinic is of great interest. Here, we present the preclinical evaluation of two potential biomarkers for the activity of ATN-224: (i) SOD activity measurements in blood cells in mice and (ii) levels of endothelial progenitor cells (EPCs) in bonnet macaques treated with ATN-224. The superoxide dismutase activity in blood cells in mice is rapidly inhibited by ATN-224 treatment at doses at which angiogenesis is maximally inhibited. Furthermore, ATN-224 dosing in bonnet macaques causes a profound and reversible decrease in EPCs without significant toxicity. Thus, both SOD activity measurements and levels of EPCs may be useful biomarkers of the antiangiogenic activity of ATN-224 to be used in its clinical development. PMID:18253124

  3. In-plane anisotropy of the electric field gradient in Ba(Fe 1 -xCox)2As2 observed by 75As NMR

    NASA Astrophysics Data System (ADS)

    Toyoda, Masayuki; Ichikawa, Akihiro; Kobayashi, Yoshiaki; Sato, Masatoshi; Itoh, Masayuki

    2018-05-01

    We have performed 75As NMR measurements on single crystals to investigate the nematic behavior via the in-plane anisotropy of the electronic state at the As site far from Co impurities in the representative iron arsenides Ba (Fe1-xCox) 2As2 . From the analysis of the angular dependence of the NMR satellites in the c plane using the binominal distribution, we find that there is the in-plane fourfold symmetry breaking, namely, the orthorhombic-type anisotropy in the electric field gradient (EFG) at the As site with no Co atom at the nearest neighboring Fe sites even in the tetragonal phase of both BaFe2As2 and Ba (Fe1-xCox) 2As2(x ≠0 ) . The NMR spectrum in the antiferromagnetically ordered state of BaFe2As2 is shown not to support a nanotwin model on the basis of the nematic order proposed from the pair-distribution analysis of neutron scattering data. Based on results of the x and temperature T dependences of the in-plane anisotropy in the wide x and T ranges, the symmetry breaking is concluded to come from the local orthorhombic domains induced by disorder such as Co impurities or lattice imperfections. Furthermore, we find that the asymmetry parameter of EFG η obeys the Curie-Weiss law which may be governed by nematic susceptibility, and the Weiss temperature becomes zero at xc˜0.05 in Ba (Fe1-xCox) 2As2 .

  4. Functionalized NaA nanozeolites labeled with 224,225Ra for targeted alpha therapy.

    PubMed

    Piotrowska, Agata; Leszczuk, Edyta; Bruchertseifer, Frank; Morgenstern, Alfred; Bilewicz, Aleksander

    2013-01-01

    The 223 Ra, 224 Ra, and 225 Ra radioisotopes exhibit very attractive nuclear properties for application in radionuclide therapy. Unfortunately the lack of appropriate bifunctional ligand for radium is the reason why these radionuclides have not found application in receptor-targeted therapy. In the present work, the potential usefulness of the NaA nanozeolite as a carrier for radium radionuclides has been studied. 224 Ra and 225 Ra, α-particle emitting radionuclides, have been absorbed in the nanometer-sized NaA zeolite (30-70 nm) through simple ion exchange. 224,225 Ra-nanozeolites exhibited very high stability in solutions containing physiological salt, EDTA, amino acids, and human serum. To make NaA nanozeolite particles dispersed in water their surface was modified with a silane coupling agent containing poly(ethylene glycol) molecules. This functionalization approach let us covalently attach a biomolecule to the NaA nanozeolite surface.

  5. The performance of Luminex ARIES® Flu A/B & RSV and Cepheid Xpert® Flu/RSV XC for the detection of influenza A, influenza B, and respiratory syncytial virus in prospective patient samples.

    PubMed

    McMullen, Phillip; Boonlayangoor, Sue; Charnot-Katsikas, Angella; Beavis, Kathleen G; Tesic, Vera

    2017-10-01

    The demand for rapid, accurate viral testing has increased the number of assays available for the detection of viral pathogens. One of the newest FDA cleared platforms is the Luminex ARIES ® Flu A/B & RSV, which is a fully automated, real-time PCR-based assay used for detection of influenza A, influenza B, and respiratory syncytial virus (RSV). We sought to compare the performance of Luminex ARIES ® Flu A/B & RSV assay to the Cepheid Xpert ® Flu/RSV XC assay for rapid Flu and RSV testing. A series of consecutive nasopharyngeal specimens received in the clinical microbiology laboratory during peak influenza season at a major academic center in Chicago, IL, were prospectively tested, using both the ARIES ® Flu A/B & RSV and Xpert ® Flu/RSV XC assays, side by side. Discrepant results were tested on the BioFire FilmArray ® Respiratory Panel for resolution. A total of 143 consecutive nasopharyngeal specimens, obtained from patients ranging from six months to ninety-three years in age were received between January 1st, 2017 and March 21st, 2017. There was 96.6% agreement between the two assays for detection influenza A, 100% agreement for detection influenza B and RSV, and 98.9% agreement for negative results. The Xpert ® Flu/RSV XC performed with an average turn-around time of approximately 60min, compared to the ARIES ® Flu A/B & RSV of approximately 120min. Both assays were equally easy to perform, with a similar amount of hands-on technologist time for each platform. Overall, these results indicate that both tests are comparable in terms of result agreement and technical ease-of-use. The Xpert ® Flu/RSV XC assay did produce results with less turn-around-time, approximately 60min quicker than the ARIES ® Flu A/B & RSV. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. 25 CFR 224.80 - Under what authority will a tribe perform activities for energy resource development?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... energy resource development? 224.80 Section 224.80 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Implementation of Tribal Energy Resource Agreements Applicable Authorities...

  7. 40 CFR 86.224-94 - Carbon dioxide analyzer calibration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Carbon dioxide analyzer calibration... PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.224-94 Carbon dioxide...

  8. 25 CFR 224.80 - Under what authority will a tribe perform activities for energy resource development?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... energy resource development? 224.80 Section 224.80 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT... development? A tribe will perform activities for energy resource development activities undertaken under a...

  9. 40 CFR 86.224-94 - Carbon dioxide analyzer calibration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission Regulations for 1994 and Later Model Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.224-94 Carbon dioxide...

  10. Exchange stiffness of Ca-doped YIG

    NASA Astrophysics Data System (ADS)

    Avgin, I.; Huber, D. L.

    1994-05-01

    An effective medium theory for the zero-temperature exchange stiffness of uncompensated Ca-doped YIG is presented. The theory is based on the assumption that the effect of the Ca impurities is to produce strong, random ferromagnetic interactions between spins on the a and d sublattices. In the simplest version of the theory, a fraction, x, of the ad exchange integrals are large and positive, x being related to the Ca concentration. The stiffness is calculated as function of x for arbitrary perturbed ad exchange integral, Jxad. For Jxad≳(1/5)‖8Jaa+3Jdd‖, with Jaa and Jdd denoting the aa and dd exchange integrals, respectively, there is a critical concentration, Xc, such that when x≳Xc, the stiffness is complex. It is suggested that Xc delineates the region where there are significant departures from colinearity in the ground state of the Fe spins. Extension of the theory to a model where the Ca doping is assumed to generate Fe4+ ions on the tetrahedral sites is discussed. Possible experimental tests of the theory are mentioned.

  11. 25 CFR 224.138 - What must the Director do if a tribe's noncompliance has caused imminent jeopardy to a physical...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... caused imminent jeopardy to a physical trust asset? 224.138 Section 224.138 Indians BUREAU OF INDIAN... TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews Noncompliance § 224.138 What must the Director do if a tribe's noncompliance has caused imminent jeopardy to a physical trust asset? If...

  12. Opposite in vivo effects of agents that stimulate or inhibit the glutamate/cysteine exchanger system xc- on the inhibition of hippocampal LTP by Aß.

    PubMed

    Zhang, Dainan; Jin, Baozhe; Ondrejcak, Tomas; Rowan, Michael J

    2016-12-01

    Aggregated amyloid ß-protein (Aß) is pathognomonic of Alzheimer's disease and certain assemblies of Aß are synaptotoxic. Excess glutamate or diminished glutathione reserve are both implicated in mediating or modulating Aß-induced disruption of synaptic plasticity. The system xc- antiporter promotes Na + -independent exchange of cystine with glutamate thereby providing a major source of extracellular glutamate and intracellular glutathione concentrations. Here we probed the ability of two drugs with opposite effects on system xc-, the inhibitor sulfasalazine and facilitator N-acetylcysteine, to modulate the ability of Aß1-42 to inhibit long-term potentiation (LTP) in the CA1 area of the anaesthetized rat. Whereas acute systemic treatment with sulfasalazine lowered the threshold for Aß to interfere with synaptic plasticity, N-acetylcysteine prevented the inhibition of LTP by Aß alone or in combination with sulfasalazine. Moreover acute N-acetylcysteine also prevented the inhibition of LTP by TNFα, a putative mediator of Aß actions, and repeated systemic N-acetylcysteine treatment for 7 days reversed the delayed deleterious effect of Aß on LTP. Since both of these drugs are widely used clinically, further evaluation of their potential beneficial and deleterious actions in early Alzheimer's disease seems warranted. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  13. 25 CFR 224.10 - What is the purpose of this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.10... resource development on tribal land; and (b) Describes the process for obtaining, implementing, and...

  14. 25 CFR 224.107 - What must a petitioner do before filing a petition with the Secretary?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must a petitioner do before filing a petition with the Secretary? 224.107 Section 224.107 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  15. 25 CFR 224.120 - What action may the Director take to ensure compliance with a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What action may the Director take to ensure compliance with a TERA? 224.120 Section 224.120 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  16. 25 CFR 224.119 - What must the Director do when making a decision on a petition?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must the Director do when making a decision on a petition? 224.119 Section 224.119 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  17. 25 CFR 224.155 - When must a tribe respond to a notice of intent to reassume?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false When must a tribe respond to a notice of intent to reassume? 224.155 Section 224.155 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  18. 25 CFR 224.155 - When must a tribe respond to a notice of intent to reassume?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When must a tribe respond to a notice of intent to reassume? 224.155 Section 224.155 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  19. 25 CFR 224.40 - How does the Act or a TERA affect the Secretary's trust responsibility?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How does the Act or a TERA affect the Secretary's trust responsibility? 224.40 Section 224.40 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  20. 25 CFR 224.107 - What must a petitioner do before filing a petition with the Secretary?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What must a petitioner do before filing a petition with the Secretary? 224.107 Section 224.107 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  1. 25 CFR 224.120 - What action may the Director take to ensure compliance with a TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What action may the Director take to ensure compliance with a TERA? 224.120 Section 224.120 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  2. Comparison of Cepheid Xpert Flu/RSV XC and BioFire FilmArray for Detection of Influenza A, Influenza B, and Respiratory Syncytial Virus.

    PubMed

    Wahrenbrock, Mark G; Matushek, Scott; Boonlayangoor, Sue; Tesic, Vera; Beavis, Kathleen G; Charnot-Katsikas, Angella

    2016-07-01

    The Xpert Flu/RSV XC was compared to the FilmArray respiratory panel for detection of influenza (Flu) A, Flu B, and respiratory syncytial virus (RSV), using 128 nasopharyngeal swabs. Positive agreements were 100% for Flu A and RSV and 92.3% for Flu B. The Xpert may be useful in clinical situations when extensive testing is not required and may serve an important role in laboratories already performing broader respiratory panel testing. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  3. A novel binary Pt 3Te x/C nanocatalyst for ethanol electro-oxidation

    NASA Astrophysics Data System (ADS)

    Huang, Meihua; Wang, Fei; Li, Lirong; Guo, Yonglang

    The Pt 3Te x/C nanocatalyst was prepared and its catalytic performance for ethanol oxidation was investigated for the first time. The Pt 3Te/C nanoparticles were characterized by an X-ray diffractometer (XRD), transmission electron microscope (TEM) and energy dispersive X-ray spectroscopy equipped with TEM (TEM-EDX). The Pt 3Te/C catalyst has a typical fcc structure of platinum alloys with the presence of Te. Its particle size is about 2.8 nm. Among the synthesized catalysts with different atomic ratios, the Pt 3Te/C catalyst has the highest anodic peak current density. The cyclic voltammograms (CV) show that the anodic peak current density for the Pt 3Te/C, commercial PtRu/C and Pt/C catalysts reaches 1002, 832 and 533 A g -1, respectively. On the current-time curve, the anodic current on the Pt 3Te/C catalyst was higher than those for the catalysts reported. So, these findings show that the Pt 3Te/C catalyst has uniform nanoparticles and the best activity among the synthesized catalysts, and it is better than commercial PtRu/C and Pt/C catalysts for ethanol oxidation at room temperature.

  4. 30 CFR 285.224 - What happens if MMS accepts my bid?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 285.224 What happens if MMS accepts my bid? If we...

  5. Rotating Disk Slurry Au Electrodeposition at Unsupported Carbon Vulcan XC-72 and Ce 3+ Impregnation for Ethanol Oxidation in Alkaline Media

    DOE PAGES

    Betancourt, Luis E.; Guzman-Blas, Rolando; Luo, Si; ...

    2016-11-19

    A robust electrodeposition method consisting of the rotating disk slurry electrode (RoDSE) technique to obtain Au nanoparticles highly dispersed on a conductive carbonaceous support, i.e., Vulcan XC-72R, for ethanol electrooxidation reaction in alkaline media was developed. Ceria was used as a cocatalyst using a Ce(III)-EDTA impregnation method in order to enhance the catalytic activity and improve the catalyst’s overall stability. Furthermore, the RoDSE method used to obtain highly dispersed Au nanoparticles does not require the use of a reducing agent or stabilizing agent, and the noble-metal loading was controlled by the addition and tuning of the metal precursor concentration. Inductivelymore » coupled plasma and thermogravimetric analysis indicated that the Au loading in the catalyst was 9 %. We determined the particle size and characteristic Au fcc crystal facets by X-ray diffraction. The morphology of the catalyst was also investigated using electron microscopy techniques. In addition, X-ray absorption spectroscopy was used to corroborate the presence and identify the oxidation state of Ce in the system and to observe if there are any electronic interactions within the 8 % Au/CeO x/C system. Cyclic voltammetry of electrodeposited 9 % Au/C and Ce-promoted 8 % Au/C showed a higher catalytic current density for ethanol oxidation when compared with commercially available catalysts (20 % Au/C) of a higher precious metal loading. Additionally, we report a higher stability toward the ethanol electrooxidation process, which was corroborated by 1 mV/s linear sweep voltammetry and chronoamperometric studies.« less

  6. 25 CFR 224.137 - What must the Director do if a tribe's noncompliance has resulted in harm or the potential for...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... resulted in harm or the potential for harm to a physical trust asset? 224.137 Section 224.137 Indians... AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews Noncompliance § 224.137 What must the Director do if a tribe's noncompliance has resulted in harm or the...

  7. 25 CFR 224.137 - What must the Director do if a tribe's noncompliance has resulted in harm or the potential for...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... resulted in harm or the potential for harm to a physical trust asset? 224.137 Section 224.137 Indians... AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews Noncompliance § 224.137 What must the Director do if a tribe's noncompliance has resulted in harm or the...

  8. 25 CFR 224.137 - What must the Director do if a tribe's noncompliance has resulted in harm or the potential for...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... resulted in harm or the potential for harm to a physical trust asset? 224.137 Section 224.137 Indians... AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews Noncompliance § 224.137 What must the Director do if a tribe's noncompliance has resulted in harm or the...

  9. 25 CFR 224.137 - What must the Director do if a tribe's noncompliance has resulted in harm or the potential for...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... resulted in harm or the potential for harm to a physical trust asset? 224.137 Section 224.137 Indians... AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews Noncompliance § 224.137 What must the Director do if a tribe's noncompliance has resulted in harm or the...

  10. 25 CFR 224.30 - What definitions apply to this part?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.30 What definitions apply to this part? Act means the Indian Tribal Energy Development and...

  11. 25 CFR 224.30 - What definitions apply to this part?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.30 What definitions apply to this part? Act means the Indian Tribal Energy Development and...

  12. 25 CFR 224.30 - What definitions apply to this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.30 What definitions apply to this part? Act means the Indian Tribal Energy Development and...

  13. 25 CFR 224.30 - What definitions apply to this part?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.30 What definitions apply to this part? Act means the Indian Tribal Energy Development and...

  14. 76 FR 40817 - Implementation of Section 224 of the Act; A National Broadband Plan for Our Future

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ...-50] Implementation of Section 224 of the Act; A National Broadband Plan for Our Future AGENCY... information collection requirements. The Office of Management and Budget (OMB) gave approval for these..., Implementation of Section 224 of the Act; A National Broadband Plan for Our Future. DATES: The final rules...

  15. Penta-P2X (X=C, Si) monolayers as wide-bandgap semiconductors: A first principles prediction

    NASA Astrophysics Data System (ADS)

    Naseri, Mosayeb; Lin, Shiru; Jalilian, Jaafar; Gu, Jinxing; Chen, Zhongfang

    2018-06-01

    By means of density functional theory computations, we predicted two novel two-dimensional (2D) nanomaterials, namely P2X (X=C, Si) monolayers with pentagonal configurations. Their structures, stabilities, intrinsic electronic, and optical properties as well as the effect of external strain to the electronic properties have been systematically examined. Our computations showed that these P2C and P2Si monolayers have rather high thermodynamic, kinetic, and thermal stabilities, and are indirect semiconductors with wide bandgaps (2.76 eV and 2.69 eV, respectively) which can be tuned by an external strain. These monolayers exhibit high absorptions in the UV region, but behave as almost transparent layers for visible light in the electromagnetic spectrum. Their high stabilities and exceptional electronic and optical properties suggest them as promising candidates for future applications in UV-light shielding and antireflection layers in solar cells.

  16. 25 CFR 224.113 - What must the tribe do after it completes petition consultation with the Director?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must the tribe do after it completes petition consultation with the Director? 224.113 Section 224.113 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT...

  17. 25 CFR 224.139 - What must a tribe do after receiving a notice of imminent jeopardy to a physical trust asset?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... jeopardy to a physical trust asset? 224.139 Section 224.139 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews Noncompliance § 224.139 What must a tribe do after receiving a notice of imminent jeopardy to a physical trust asset? (a) Upon receipt of a notice of imminent...

  18. Measurement of 224Ra and 226Ra activities in natural waters using a radon-in-air monitor

    USGS Publications Warehouse

    Kim, G.; Burnett, W.C.; Dulaiova, H.; Swarzenski, P.W.; Moore, W.S.

    2001-01-01

    We report a simple new technique for measuring low-level radium isotopes (224Ra and 226Ra) in natural waters. The radium present in natural waters is first preconcentrated onto MnO2-coated acrylic fiber (Mn fiber) in a column mode. The radon produced from the adsorbed radium is then circulated through a closed air-loop connected to a commercial radon-in-air monitor. The monitor counts alpha decays of radon daughters (polonium isotopes) which are electrostatically collected onto a silicon semiconductor detector. Count data are collected in energy-specific windows, which eliminate interference and maintain very low backgrounds. Radium-224 is measured immediately after sampling via 220Rn (216Po), and 226Ra is measured via 222Rn (218Po) after a few days of ingrowth of 222Rn. This technique is rapid, simple, and accurate for measurements of low-level 224Ra and 226Ra activities without requiring any wet chemistry. Rapid measurements of short-lived 222Rn and 224Ra, along with long-lived 226Ra, may thus be made in natural waters using a single portable system for environmental monitoring of radioactivity as well as tracing of various geochemical and geophysical processes. The technique could be especially useful for the on-site rapid determination of 224Ra which has recently been found to occur at elevated activities in some groundwater wells.

  19. 25 CFR 224.141 - What must the Secretary do if the tribe responds to the Director's order?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must the Secretary do if the tribe responds to the Director's order? 224.141 Section 224.141 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  20. 25 CFR 224.117 - Must the Director make a determination of the tribe's compliance with a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Must the Director make a determination of the tribe's compliance with a TERA? 224.117 Section 224.117 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  1. 25 CFR 224.117 - Must the Director make a determination of the tribe's compliance with a TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Must the Director make a determination of the tribe's compliance with a TERA? 224.117 Section 224.117 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  2. 25 CFR 224.56 - What is the effect of the Director's receipt of a tribe's complete application?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the effect of the Director's receipt of a tribe's complete application? 224.56 Section 224.56 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  3. 18 CFR 367.2240 - Account 224, Other long-term debt.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 224, Other long-term debt. 367.2240 Section 367.2240 Conservation of Power and Water Resources FEDERAL ENERGY..., FEDERAL POWER ACT AND NATURAL GAS ACT UNIFORM SYSTEM OF ACCOUNTS FOR CENTRALIZED SERVICE COMPANIES SUBJECT...

  4. 224. Photocopy of drawing (1963 structural drawing by General Dynamics/Astronautics) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    224. Photocopy of drawing (1963 structural drawing by General Dynamics/Astronautics) UMBILICAL MAST WIND DEFLECTOR REQUIRED FOR 206 PROGRAM, PAD, SHEET S-101 - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  5. The Marshall Space Flight Center Development of Mirror Modules for the ART-XC Ins1rument Aboard the Spectrum-Roentgen-Gamma Mission

    NASA Technical Reports Server (NTRS)

    Gubarev, M.; Ramsey, B.; ODell, S. L.; Elsner, R.; Kilaru, K.; McCracken, J.; Pavlinsky, M.; Tkachenko, A.; Lapshov, I.

    2012-01-01

    The Spectrum-Rontgen-Gamma (SRG) mission is a Russian-German X-ray astrophysical observatory that carries two co-aligned and complementary X-ray telescope systems. The primary instrument is the German-led extended ROentgen Survey with an Imaging Telescope Array (eROSITA), a 7-module X-ray telescope system that covers the energy range from 0.2-12 keV. The complementary instrument is the Russian-led Astronomical Roentgen Telescope -- X-ray Concentrator (ART-XC or ART), a 7-module X-ray telescope system that provides higher energy coverage, up to 30 keV (with limited sensitivity above 12 keV).

  6. 49 CFR Appendix A to Part 224 - Schedule of Civil Penalties1

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... § 224.105Sheeting dimensions and quantity: Failure to apply minimum amount of retroreflective sheeting in accordance with Table 2 2,500 5,000 Applying retroreflective sheeting of wrong dimensions 2,500 5...

  7. 30 CFR 250.224 - What information on support vessels, offshore vehicles, and aircraft you will use must accompany...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What information on support vessels, offshore vehicles, and aircraft you will use must accompany the EP? 250.224 Section 250.224 Mineral Resources BUREAU... GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Contents of...

  8. 10 CFR 431.224 - Uniform test method for the measurement of energy consumption for traffic signal modules and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Uniform test method for the measurement of energy consumption for traffic signal modules and pedestrian modules. 431.224 Section 431.224 Energy DEPARTMENT OF... measurement of energy consumption for traffic signal modules and pedestrian modules. (a) Scope. This section...

  9. 25 CFR 224.131 - What is a periodic review and evaluation?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 224.131 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews... the Director performs to monitor a tribe's performance of activities associated with the development...

  10. 25 CFR 224.131 - What is a periodic review and evaluation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 224.131 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews... the Director performs to monitor a tribe's performance of activities associated with the development...

  11. 25 CFR 224.153 - Must the Secretary notify the tribe of an intent to reassume the authority granted?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Must the Secretary notify the tribe of an intent to reassume the authority granted? 224.153 Section 224.153 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT...

  12. 25 CFR 224.109 - What must a petitioner claim or request in a petition filed with the Secretary?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What must a petitioner claim or request in a petition filed with the Secretary? 224.109 Section 224.109 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT...

  13. 25 CFR 224.153 - Must the Secretary notify the tribe of an intent to reassume the authority granted?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Must the Secretary notify the tribe of an intent to reassume the authority granted? 224.153 Section 224.153 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT...

  14. MiR-224 targets the 3'UTR of type 1 5'-iodothyronine deiodinase possibly contributing to tissue hypothyroidism in renal cancer.

    PubMed

    Boguslawska, Joanna; Wojcicka, Anna; Piekielko-Witkowska, Agnieszka; Master, Adam; Nauman, Alicja

    2011-01-01

    Type 1 iodothyronine deiodinase (DIO1) catalyses the conversion of prohormone thyroxine to the active thyroid hormone 3,3',5-triiodothyronine (T3), important regulator of cell proliferation and differentiation. DIO1 expression is reduced in the most common type of kidney neoplasia, clear cell Renal Cell Carcinoma (ccRCC). MicroRNAs are small, non-coding RNAs that regulate gene expression at posttranscriptional levels. The aim of this study was to analyze the potential regulation of DIO1 expression by microRNAs in ccRCC. Bioinformatic analysis revealed that 3'UTR of the human DIO1 gene transcript contains miR-224 and miR-383 target sites, which are conserved across mammalian species. Semi-quantitative real-time PCR was used to analyze the expression of miR-224 and miR-383 in 32 samples of ccRCC tumors (T) and in 32 matched control (C) samples. We observed statistically significant (p = 0.0002) more than four fold increase in miR-224 expression and nearly two fold increase in miR-383 expression in samples T compared to samples C. Tumor specific changes in expression of miR-224 negatively correlated with changes in DIO1 expression and intracellular T3 concentration. Transfection of HeLa cell line with miR-224 and miR-383 suppressed the activity of a luciferase reporter containing the 3'UTR of DIO1. This was abolished when constructs mutated at the miR-224 and miR-383 target sites were used instead, indicating that miR-224 and miR-383 directly bind to DIO1 3'UTR. Finally, induced expression of miR-224 in Caki-2 cells resulted in significant (p<0.01) reduction of DIO1 mRNA. This study provides a novel miRNA-mediated regulatory mechanism of DIO1 expression in ccRCC.

  15. 27 CFR 44.224 - Inspection by an appropriate TTB officer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... CIGARETTE PAPERS AND TUBES, WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK OF TAX Drawback of Tax § 44.224... tobacco products, and cigarette papers and tubes listed on TTB Form 5620.7. Such officer will verify the... and send a copy to the TTB office listed on the form. (e) Release. After executing the report of...

  16. 27 CFR 44.224 - Inspection by an appropriate TTB officer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... CIGARETTE PAPERS AND TUBES, WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK OF TAX Drawback of Tax § 44.224... tobacco products, and cigarette papers and tubes listed on TTB Form 5620.7. Such officer will verify the... and send a copy to the TTB office listed on the form. (e) Release. After executing the report of...

  17. 27 CFR 44.224 - Inspection by an appropriate TTB officer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... CIGARETTE PAPERS AND TUBES, WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK OF TAX Drawback of Tax § 44.224... tobacco products, and cigarette papers and tubes listed on TTB Form 5620.7. Such officer will verify the... and send a copy to the TTB office listed on the form. (e) Release. After executing the report of...

  18. 27 CFR 44.224 - Inspection by an appropriate TTB officer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... CIGARETTE PAPERS AND TUBES, WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK OF TAX Drawback of Tax § 44.224... tobacco products, and cigarette papers and tubes listed on TTB Form 5620.7. Such officer will verify the... and send a copy to the TTB office listed on the form. (e) Release. After executing the report of...

  19. 27 CFR 44.224 - Inspection by an appropriate TTB officer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CIGARETTE PAPERS AND TUBES, WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK OF TAX Drawback of Tax § 44.224... tobacco products, and cigarette papers and tubes listed on TTB Form 5620.7. Such officer will verify the... and send a copy to the TTB office listed on the form. (e) Release. After executing the report of...

  20. Green synthesis of Fe3O4 nanoparticles loaded sawdust carbon for cadmium (II) removal from water: Regeneration and mechanism.

    PubMed

    Kataria, Navish; Garg, V K

    2018-06-04

    This study focused on the synthesis and characterization of novel magnetic iron oxide nanoparticles loaded sawdust carbon (Fe 3 O 4 /SC) and EDTA modified Fe 3 O 4 /SC (EDTA@Fe 3 O 4 /SC) nanocomposites (ncs) by low cost biogenic green synthesis approach and their application for Cd (II) removal from aqueous medium in batch mode. In isotherm studies, Langmuir and Freundlich models are best fitted to Cd (II) removal data. Langmuir maximum adsorption capacity of EDTA@Fe 3 O 4 /SC ncs was found to be 63.3, 22.4 and 25 mg/g that is greater than maximum adsorption capacity of Fe 3 O 4 /SC ncs that is 51, 18.9 and 15 mg/g at the adsorbent doses of 0.4, 1.2 and 2.0 g/L, respectively. Cd (II) adsorption rate is well explained by Pseudo-second order model. Cd (II) adsorption process is spontaneous and endothermic in nature expressed by Enthalpy, Entropy and Free Energy change. The results of regeneration studies showed that EDTA modified Fe 3 O 4 /SC ncs is promising, low cost and eco-friendly for heavy metal adsorption. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. 25 CFR 224.87 - What are the obligations of a tribe if it discovers a violation or breach?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What are the obligations of a tribe if it discovers a violation or breach? 224.87 Section 224.87 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF...

  2. 25 CFR 224.50 - What is the purpose of this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....50 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Procedures for Obtaining Tribal Energy Resource Agreements § 224.50 What is the purpose of this subpart? This subpart...

  3. 20 CFR 10.224 - What happens if OWCP finds that the employee is not entitled to COP after it has been paid?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... is not entitled to COP after it has been paid? 10.224 Section 10.224 Employees' Benefits OFFICE OF... Termination of Cop § 10.224 What happens if OWCP finds that the employee is not entitled to COP after it has been paid? Where OWCP finds that the employee is not entitled to COP after it has been paid, the...

  4. 20 CFR 10.224 - What happens if OWCP finds that the employee is not entitled to COP after it has been paid?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... is not entitled to COP after it has been paid? 10.224 Section 10.224 Employees' Benefits OFFICE OF... Termination of Cop § 10.224 What happens if OWCP finds that the employee is not entitled to COP after it has been paid? Where OWCP finds that the employee is not entitled to COP after it has been paid, the...

  5. 20 CFR 10.224 - What happens if OWCP finds that the employee is not entitled to COP after it has been paid?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... is not entitled to COP after it has been paid? 10.224 Section 10.224 Employees' Benefits OFFICE OF... Termination of Cop § 10.224 What happens if OWCP finds that the employee is not entitled to COP after it has been paid? Where OWCP finds that the employee is not entitled to COP after it has been paid, the...

  6. 20 CFR 10.224 - What happens if OWCP finds that the employee is not entitled to COP after it has been paid?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... is not entitled to COP after it has been paid? 10.224 Section 10.224 Employees' Benefits OFFICE OF... Termination of Cop § 10.224 What happens if OWCP finds that the employee is not entitled to COP after it has been paid? Where OWCP finds that the employee is not entitled to COP after it has been paid, the...

  7. 20 CFR 10.224 - What happens if OWCP finds that the employee is not entitled to COP after it has been paid?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... is not entitled to COP after it has been paid? 10.224 Section 10.224 Employees' Benefits OFFICE OF... Termination of Cop § 10.224 What happens if OWCP finds that the employee is not entitled to COP after it has been paid? Where OWCP finds that the employee is not entitled to COP after it has been paid, the...

  8. Multiple magnetization steps and plateaus across the antiferromagnetic to ferromagnetic transition in L a1 -xC exF e12B6 : Time delay of the metamagnetic transitions

    NASA Astrophysics Data System (ADS)

    Diop, L. V. B.; Isnard, O.

    2018-01-01

    The effects of cerium substitution on the structural and magnetic properties of the L a1 -xC exF e12B6 (0 ≤x ≤0.175 ) series of compounds have been studied. All of the compounds exhibit an antiferromagnetic ground state below the Néel temperature TN≈36 K . Both antiferromagnetic and paramagnetic states can be transformed into the ferromagnetic state irreversibly and reversibly depending on the magnitude of the applied magnetic field, the temperature, and the direction of their changes. Of particular interest is the low-temperature magnetization process. This process is discontinuous and evolves unexpected huge metamagnetic transitions consisting of a succession of sharp magnetization steps separated by plateaus, giving rise to an unusual avalanchelike behavior. At constant temperature and magnetic field, the evolution with time of the magnetization displays a spectacular spontaneous jump after a long incubation time. L a1 -xC exF e12B6 compounds exhibit a unique combination of exceptional features like large thermal hysteresis, giant magnetization jumps, and remarkably huge magnetic hysteresis for the field-induced first-order metamagnetic transition.

  9. 25 CFR 224.10 - What is the purpose of this part?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.10... discretion, may enter into and manage leases, business agreements, and rights-of-way for purposes of energy...

  10. The role of system Xc- in methamphetamine-induced dopaminergic neurotoxicity in mice.

    PubMed

    Dang, Duy-Khanh; Shin, Eun-Joo; Tran, Hai-Quyen; Kim, Dae-Joong; Jeong, Ji Hoon; Jang, Choon-Gon; Nah, Seung-Yeol; Sato, Hideyo; Nabeshima, Toshitaka; Yoneda, Yukio; Kim, Hyoung-Chun

    2017-09-01

    The cystine/glutamate antiporter (system Xc - , Sxc) transports cystine into cell in exchange for glutamate. Since xCT is a specific subunit of Sxc, we employed xCT knockout mice and investigated whether this antiporter affected methamphetamine (MA)-induced dopaminergic neurotoxicity. MA treatment significantly increased striatal oxidative burdens in wild type mice. xCT inhibitor [i.e., S-4-carboxy-phenylglycine (CPG), sulfasalazine] or an xCT knockout significantly protected against these oxidative burdens. MA-induced increases in Iba-1 expression and Iba-1-labeled microglial immunoreactivity (Iba-1-IR) were significantly attenuated by CPG or sulfasalazine administration or xCT knockout. CPG or sulfasalazine significantly attenuated MA-induced TUNEL-positive cell populations in the striatum of Taconic ICR mice. The decrease in excitatory amino acid transporter-2 (or glutamate transporter-1) expression and increase in glutamate release were attenuated by CPG, sulfasalazine or xCT knockout. In addition, CPG, sulfasalazine or xCT knockout significantly protected against dopaminergic loss (i.e., decreases in tyrosine hydroxylase expression and immunoreactivity, and an increase in dopamine turnover rate) induced by MA. However, CPG, sulfasalazine or xCT knockout did not significantly affect the impaired glutathione system [i.e., decrease in reduced glutathione (GSH) and increase in oxidized glutathione (GSSG)] induced by MA. Our results suggest that Sxc mediates MA-induced neurotoxicity via facilitating oxidative stress, microgliosis, proapoptosis, and glutamate-related toxicity. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. The Gibbs free energy of nukundamite (Cu3.38Fe0.62S4): A correction and implications for phase equilibria

    USGS Publications Warehouse

    Seal, R.R.; Inan, E.E.; Hemingway, B.S.

    2001-01-01

    The Gibbs free energy of formation of nukundamite (Cu3.38Fe0.62S4) was calculated from published experimental studies of the reaction 3.25 Cu3.38Fe0.62S4 + S2 = 11 CuS + 2 FeS2 in order to correct an erroneous expression in the published record. The correct expression describing the Gibbs free energy of formation (kJ???mol-1) of nukundamite relative to the elements and ideal S2 gas is ??fG?? nukundamite T(K) = -549.75 + 0.23242 T + 3.1284 T0.5, with an uncertainty of 0.6%. An evaluation of the phase equilibria of nukundamite with associated phases in the system Cu-Fe-S as a function of temperature and sulfur fugacity indicates that nukundamite is stable from 224 to 501??C at high sulfidation states. At its greatest extent, at 434??C, the stability field of nukundamite is only 0.4 log f(S2) units wide, which explains its rarity. Equilibria between nukundamite and bornite, which limit the stability of both phases, involve bornite compositions that deviate significantly from stoichiometric Cu5FeS4. Under equilibrium conditions in the system Cu-Fe-S, nukundamite + chalcopyrite is not a stable assemblage at any temperature.

  12. Occurrence of radium-224, radium-226, and radium-228 in water of the unconfined Kirkwood-Cohansey aquifer system, southern New Jersey

    USGS Publications Warehouse

    Szabo, Zoltan; dePaul, Vincent T.; Kraemer, Thomas F.; Parsa, Bahman

    2005-01-01

    Water in the unconfined Kirkwood-Cohansey aquifer system in the New Jersey Coastal Plain contains elevated concentrations (above 3 pCi/L (picocuries per liter)) of the alpha-particle-emitting radionuclide radium-224. Previously, water from the aquifer system had been found to contain radium-226 and radium-228. This observation is of concern because the previously undetected presence of radium-224 may pose an additional, quantifiable health risk that currently is not accounted for by the Maximum Contaminant Level (MCL) of 5 pCi/L for combined radium (the sum of radium-226 plus radium-228 is termed 'combined radium') in drinking water. Water samples were collected from a regional network of 88 wells for determination of concentrations of radium-224, radium-226, and radium-228; gross alpha-particle activity; and concentrations of major ions and selected trace elements. Both gamma and alpha spectroscopic techniques were used to determine concentrations of radium-224, which ranged from <0.5 to 16.8 pCi/L (median 2.1 pCi/L, interquartile range 1.2-3.7 pCi/L). Concentrations of radium-226 and radium-228 in the same samples ranged from <0.5 to 17.4 pCi/L (median 1.7 pCi/L, interquartile range 0.9-2.9 pCi/L) and <0.5 to 12.8 pCi/L (median 1.6 pCi/L, interquartile range, 0.9-2.6 pCi/L), respectively. Concentrations of radium-224 typically were greater than those of the other two radium radionuclides, as evidenced by the highest median, third quartile, and maximum concentrations, as well as the highest concentration among the three radium radioisotopes in 52 (59 percent) of the 88 samples. Concentrations of 5.0 to 5.5 pCi/L of radium-224 result in a gross alpha-particle activity of about 15 pCi/L (the MCL) 36 to 48 hours, respectively, after sample collection when ingrowth of radium-224 progeny radionuclides is considered, even with the unlikely assumption that no other alpha-particle-emitting radionuclide is present in the water. Concentrations of 3.4 to 3.7 pCi/L radium-224

  13. A scanning electron microscopy study of the macro-crystalline structure of 2-(2,4-dinitrobenzyl) pyridine

    NASA Technical Reports Server (NTRS)

    Ware, Jacqueline; Hammond, Ernest C., Jr.

    1989-01-01

    The compound, 2-(2,4-dinitrobenzyl) pyridine, was synthesized in the laboratory; an introductory level electron microscopy study of the macro-crystalline structure was conducted using the scanning electron microscope (SEM). The structure of these crystals was compared with the macrostructure of the crystal of 2-(2,4-dinitrobenzyl) pyridinium bromide, the hydrobromic salt of the compound which was also synthesized in the laboratory. A scanning electron microscopy crystal study was combined with a study of the principle of the electron microscope.

  14. Capacity fade in high energy silicon-graphite electrodes for lithium-ion batteries

    DOE PAGES

    Dose, W. M.; Piernas-Munoz, M. J.; Maroni, V. A.; ...

    2018-02-09

    A silicon-graphite blended anode is paired with a high capacity LiFePO 4 reference/counter electrode to track irreversibility and lithium inventory. The LiFePO 4 electrode provides a reliable, flat potential for dQ dV -1 analysis of Li xSi and Li xC electrochemical reactions. We can relate this electrochemistry to the morphological and physical changes taking place.

  15. Capacity fade in high energy silicon-graphite electrodes for lithium-ion batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dose, W. M.; Piernas-Munoz, M. J.; Maroni, V. A.

    A silicon-graphite blended anode is paired with a high capacity LiFePO 4 reference/counter electrode to track irreversibility and lithium inventory. The LiFePO 4 electrode provides a reliable, flat potential for dQ dV -1 analysis of Li xSi and Li xC electrochemical reactions. We can relate this electrochemistry to the morphological and physical changes taking place.

  16. 20 CFR 725.224 - Determination of relationship; parent, brother, or sister.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Determination of relationship; parent... Benefits) § 725.224 Determination of relationship; parent, brother, or sister. (a) An individual will be considered to be the parent, brother, or sister of a miner if the courts of the State in which the miner was...

  17. 24 CFR 200.224 - Multifamily Participation Review Committee and Participation Control Officer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Multifamily Participation Review... § 200.224 Multifamily Participation Review Committee and Participation Control Officer. The membership and authority of the Multifamily Participation Review Committee (hereinafter referred to as the Review...

  18. 24 CFR 200.224 - Multifamily Participation Review Committee and Participation Control Officer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Multifamily Participation Review... § 200.224 Multifamily Participation Review Committee and Participation Control Officer. The membership and authority of the Multifamily Participation Review Committee (hereinafter referred to as the Review...

  19. 24 CFR 200.224 - Multifamily Participation Review Committee and Participation Control Officer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Multifamily Participation Review... § 200.224 Multifamily Participation Review Committee and Participation Control Officer. The membership and authority of the Multifamily Participation Review Committee (hereinafter referred to as the Review...

  20. 24 CFR 200.224 - Multifamily Participation Review Committee and Participation Control Officer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Multifamily Participation Review... § 200.224 Multifamily Participation Review Committee and Participation Control Officer. The membership and authority of the Multifamily Participation Review Committee (hereinafter referred to as the Review...

  1. 25 CFR 224.41 - When does the Secretary require agreement of more than one tribe to approve a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false When does the Secretary require agreement of more than one tribe to approve a TERA? 224.41 Section 224.41 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT...

  2. 25 CFR 224.152 - Must the Secretary always reassume the activities upon a finding of imminent jeopardy to a...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... reassume the activities upon a finding of imminent jeopardy to a physical trust asset? (a) The Secretary... 25 Indians 1 2011-04-01 2011-04-01 false Must the Secretary always reassume the activities upon a finding of imminent jeopardy to a physical trust asset? 224.152 Section 224.152 Indians BUREAU OF INDIAN...

  3. 25 CFR 224.152 - Must the Secretary always reassume the activities upon a finding of imminent jeopardy to a...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... reassume the activities upon a finding of imminent jeopardy to a physical trust asset? (a) The Secretary... 25 Indians 1 2010-04-01 2010-04-01 false Must the Secretary always reassume the activities upon a finding of imminent jeopardy to a physical trust asset? 224.152 Section 224.152 Indians BUREAU OF INDIAN...

  4. Fe Isotope Fractionation During Fe(III) Reduction to Fe(II)

    NASA Astrophysics Data System (ADS)

    Baker, E. A.; Greene, S.; Hardin, E. E.; Hodierne, C. E.; Rosenberg, A.; John, S.

    2014-12-01

    The redox chemistry of Fe(III) and Fe(II) is tied to a variety of earth processes, including biological, chemical, or photochemical reduction of Fe(III) to Fe(II). Each process may fractionate Fe isotopes, but the magnitudes of the kinetic isotope effects have not been greatly explored in laboratory conditions. Here, we present the isotopic fractionation of Fe during reduction experiments under a variety of experimental conditions including photochemical reduction of Fe(III) bound to EDTA or glucaric acid, and chemical reduction of Fe-EDTA by sodium dithionite, hydroxylamine hydrochloride, Mn(II), and ascorbic acid. A variety of temperatures and pHs were tested. In all experiments, Fe(III) bound to an organic ligand was reduced in the presence of ferrozine. Ferrozine binds with Fe(II), forming a purple complex which allows us to measure the extent of reaction. The absorbance of the experimental solutions was measured over time to determine the Fe(II)-ferrozine concentration and thus the reduction rate. After about 5% of the Fe(III) was reduced, Fe(III)-EDTA and Fe(II)-ferrozine were separated using a C-18 column to which Fe(II)-ferrozine binds. The Fe(II) was eluted and purified through anion exchange chromatography for analysis of δ56Fe by MC-ICPMS. Preliminary results show that temperature and pH both affect reduction rate. All chemical reductants tested reduce Fe(III) at a greater rate as temperature increases. The photochemical reductant EDTA reduces Fe(III) at a greater rate under more acidic conditions. Comparison of the two photochemical reductants shows that glucaric acid reduces Fe(III) significantly faster than EDTA. For chemical reduction, the magnitude of isotopic fractionation depends on the reductant used. Temperature and pH also affect the isotopic fractionation of Fe. Experiments using chemical reductants show that an increase in temperature at low temperatures produces lighter 56Fe ratios, while at high temperatures some reductants produce heavier

  5. MicroRNA-224 is Readily Detectable in Urine of Individuals with Diabetes Mellitus and is a Potential Indicator of Beta-Cell Demise

    PubMed Central

    Bacon, Siobhán; Engelbrecht, Britta; Schmid, Jasmin; Pfeiffer, Shona; Gallagher, Ross; McCarthy, Ailbhe; Burke, Marie; Concannon, Caoimhín; Prehn, Jochen H. M.; Byrne, Maria M.

    2015-01-01

    MicroRNA (miRNA) are a class of non-coding, 19–25 nucleotide RNA critical for network-level regulation of gene expression. miRNA serve as paracrine signaling molecules. Using an unbiased array approach, we previously identified elevated levels of miR-224 and miR-103 to be associated with a monogenic form of diabetes; HNF1A-MODY. miR-224 is a novel miRNA in the field of diabetes. We sought to explore the role of miR-224 as a potential biomarker in diabetes, and whether such diabetes-associated-miRNA can also be detected in the urine of patients. Absolute levels of miR-224 and miR-103 were determined in the urine of n = 144 individuals including carriers of a HNF1A mutation, participants with type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM) and normal controls. Expression levels were correlated with clinical and biochemical parameters. miR-224 was significantly elevated in the urine of carriers of a HNF1A mutation and participants with T1DM. miR-103 was highly expressed in urine across all diabetes cohorts when compared to controls. For both miR-224 and-103, we found a significant correlation between serum and urine levels (p < 0.01). We demonstrate that miRNA can be readily detected in the urine independent of clinical indices of renal dysfunction. We surmise that the differential expression levels of miR-224 in both HNF1A-MODY mutation carriers and T1DM may be an attempt to compensate for beta-cell demise. PMID:26110317

  6. A quantitative relationship for the shock sensitivities of energetic compounds based on X-NO(2) (X=C, N, O) bond dissociation energy.

    PubMed

    Li, Jinshan

    2010-08-15

    The ZPE-corrected X-NO(2) (X=C, N, O) bond dissociation energies (BDEs(ZPE)) of 11 energetic nitrocompounds of different types have been calculated employing density functional theory methods. Computed results show that using the 6-31G** basis set the UB3LYP calculated BDE(ZPE) is less than the UB3P86. For these typical energetic nitrocompounds the shock-initiated pressure (P(98)) is strongly related to the BDE(ZPE) indeed, and a polynomial correlation of ln(P(98)) with the BDE(ZPE) has been established successfully at different density functional theory levels, which provides a method to address the shock sensitivity problem. Copyright 2010 Elsevier B.V. All rights reserved.

  7. Structural, elastic and electronic properties of transition metal carbides ZnC, NbC and their ternary alloys ZnxNb1-xC

    NASA Astrophysics Data System (ADS)

    Zidi, Y.; Méçabih, S.; Abbar, B.; Amari, S.

    2018-02-01

    We have investigated the structural, electronic and elastic properties of transition-metal carbides ZnxNb1-xC alloys in the range of 0 ≤ x ≤ 1 using the density functional theory (DFT). The full potential linearized augmented plane wave (FP-LAPW) method within a framework of the generalized gradient approximation (GGA) and GGA + U (where U is the Hubbard correlation terms) approach is used to perform the calculations presented here. The lattice parameters, the bulk modulus, its pressure derivative and the elastic constants were determined. We have obtained Young's modulus, shear modulus, Poisson's ratio, anisotropy factor by the aid of the calculated elastic constants. We discuss the total and partial densities of states and charge densities.

  8. Measuring the radium quartet (228Ra, 226Ra, 224Ra, 223Ra) in seawater samples using gamma spectrometry.

    PubMed

    van Beek, P; Souhaut, M; Reyss, J-L

    2010-07-01

    Radium isotopes are widely used in marine studies (eg. to trace water masses, to quantify mixing processes or to study submarine groundwater discharge). While 228Ra and 226Ra are usually measured using gamma spectrometry, short-lived Ra isotopes (224Ra and 223Ra) are usually measured using a Radium Delayed Coincidence Counter (RaDeCC). Here we show that the four radium isotopes can be analyzed using gamma spectrometry. We report 226Ra, 228Ra, 224Ra, 223Ra activities measured using low-background gamma spectrometry in standard samples, in water samples collected in the vicinity of our laboratory (La Palme and Vaccarès lagoons, France) but also in seawater samples collected in the plume of the Amazon river, off French Guyana (AMANDES project). The 223Ra and 224Ra activities determined in these samples using gamma spectrometry were compared to the activities determined using RaDeCC. Activities determined using the two techniques are in good agreement. Uncertainties associated with the 224Ra activities are similar for the two techniques. RaDeCC is more sensitive for the detection of low 223Ra activities. Gamma spectrometry thus constitutes an alternate method for the determination of short-lived Ra isotopes. 2009 Elsevier Ltd. All rights reserved.

  9. Closure Report for Corrective Action Unit 224: Decon Pad and Septic Systems, Nevada Test Site, Nevada

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NSTec Environmental Restoration

    Corrective Action Unit (CAU) 224 is located in Areas 02, 03, 05, 06, 11, and 23 of the Nevada Test Site, which is situated approximately 65 miles northwest of Las Vegas, Nevada. CAU 224 is listed in the Federal Facility Agreement and Consent Order (FFACO) of 1996 as Decon Pad and Septic Systems and is comprised of the following nine Corrective Action Sites (CASs): CAS 02-04-01, Septic Tank (Buried); CAS 03-05-01, Leachfield; CAS 05-04-01, Septic Tanks (4)/Discharge Area; CAS 06-03-01, Sewage Lagoons (3); CAS 06-05-01, Leachfield; CAS 06-17-04, Decon Pad and Wastewater Catch; CAS 06-23-01, Decon Pad Discharge Piping; CASmore » 11-04-01, Sewage Lagoon; and CAS 23-05-02, Leachfield. The Nevada Division of Environmental Protection (NDEP)-approved corrective action alternative for CASs 02-04-01, 03-05-01, 06-03-01, 11-04-01, and 23-05-02 is no further action. As a best management practice, the septic tanks and distribution box were removed from CASs 02-04-01 and 11-04-01 and disposed of as hydrocarbon waste. The NDEP-approved correction action alternative for CASs 05-04-01, 06-05-01, 06-17-04, and 06-23-01 is clean closure. Closure activities for these CASs included removing and disposing of radiologically and pesticide-impacted soil and debris. CAU 224 was closed in accordance with the NDEP-approved CAU 224 Corrective Action Plan (CAP). The closure activities specified in the CAP were based on the recommendations presented in the CAU 224 Corrective Action Decision Document (U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office, 2005). This Closure Report documents CAU 224 closure activities. During closure activities, approximately 60 cubic yards (yd3) of mixed waste in the form of soil and debris; approximately 70 yd{sup 3} of sanitary waste in the form of soil, liquid from septic tanks, and concrete debris; approximately 10 yd{sup 3} of hazardous waste in the form of pesticide-impacted soil; approximately 0.5 yd{sup 3} of universal

  10. A facile route to the synthesis of magnetically separable BiOBr/NiFe2O4 composites with enhanced photocatalytic performance

    NASA Astrophysics Data System (ADS)

    Li, Xiaowei; Wang, Li; Zhang, Lei; Zhuo, Shuping

    2017-10-01

    Novel magnetically separable BiOBr/NiFe2O4 composite photocatalysts with different mass ratios were fabricated through a facile hydrothermal treatment. The phases, morphologies and photophysical properties of the as-obtained samples were characterized by X-ray diffraction (XRD), energy dispersive spectrometry (EDS), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), transmission electron microcopy (TEM) and diffuse reflection spectroscopy (DRS). Their visible light photocatalytic performances were examined by degradation of methylene blue (MB) and phenol. Compared with bare BiOBr and NiFe2O4, all heterostructured BiOBr/NiFe2O4 nanocomposites exhibited significantly enhanced photocatalytic efficiency. The BiOBr/NiFe2O4-20% composite showed the highest photodegradation capacity, which was about 3.2 and 22.4 times greater than that of individual BiOBr and NiFe2O4, respectively. The degradation efficiency of BiOBr/NiFe2O4-20% in the degradation of MB dye hardly changed after five cycles, signifying that the BiOBr/NiFe2O4-20% photocatalyst had excellent recyclability. In addition, BiOBr/NiFe2O4 composite photocatalysts could be easily separated from contaminant solution by using a magnet and recycled, exhibiting great potential for application in the fields of environmental purification of organic pollutants and wastewater treatment. In the light of experimental results, we proposed a photocatalytic mechanism which confirmed that the enhancement of photocatalytic performance for BiOBr/NiFe2O4 composites was mainly ascribed to the efficient separation of photo-induced charges resulting from the well-known "heterostructure effect" between NiFe2O4 nanorods and BiOBr nanosheets.

  11. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.

    PubMed

    Miller, Clint L; Haas, Ulrike; Diaz, Roxanne; Leeper, Nicholas J; Kundu, Ramendra K; Patlolla, Bhagat; Assimes, Themistocles L; Kaiser, Frank J; Perisic, Ljubica; Hedin, Ulf; Maegdefessel, Lars; Schunkert, Heribert; Erdmann, Jeanette; Quertermous, Thomas; Sczakiel, Georg

    2014-03-01

    Genome-wide association studies (GWAS) have identified chromosomal loci that affect risk of coronary heart disease (CHD) independent of classical risk factors. One such association signal has been identified at 6q23.2 in both Caucasians and East Asians. The lead CHD-associated polymorphism in this region, rs12190287, resides in the 3' untranslated region (3'-UTR) of TCF21, a basic-helix-loop-helix transcription factor, and is predicted to alter the seed binding sequence for miR-224. Allelic imbalance studies in circulating leukocytes and human coronary artery smooth muscle cells (HCASMC) showed significant imbalance of the TCF21 transcript that correlated with genotype at rs12190287, consistent with this variant contributing to allele-specific expression differences. 3' UTR reporter gene transfection studies in HCASMC showed that the disease-associated C allele has reduced expression compared to the protective G allele. Kinetic analyses in vitro revealed faster RNA-RNA complex formation and greater binding of miR-224 with the TCF21 C allelic transcript. In addition, in vitro probing with Pb2+ and RNase T1 revealed structural differences between the TCF21 variants in proximity of the rs12190287 variant, which are predicted to provide greater access to the C allele for miR-224 binding. miR-224 and TCF21 expression levels were anti-correlated in HCASMC, and miR-224 modulates the transcriptional response of TCF21 to transforming growth factor-β (TGF-β) and platelet derived growth factor (PDGF) signaling in an allele-specific manner. Lastly, miR-224 and TCF21 were localized in human coronary artery lesions and anti-correlated during atherosclerosis. Together, these data suggest that miR-224 interaction with the TCF21 transcript contributes to allelic imbalance of this gene, thus partly explaining the genetic risk for coronary heart disease associated at 6q23.2. These studies implicating rs12190287 in the miRNA-dependent regulation of TCF21, in conjunction with

  12. Electrical and Magnetic Properties of Binary Amorphous Transition Metal Alloys.

    NASA Astrophysics Data System (ADS)

    Liou, Sy-Hwang

    The electrical, superconductive and magnetic properties of several binary transition metal amorphous and metastable crystalline alloys, Fe(,x)Ti(,100-x) (30 (LESSTHEQ) x (LESSTHEQ) 100), Fe(,x)Zr(,100-x) (20 (LESSTHEQ) x (LESSTHEQ) 93), Fe(,x)Hf(,100-x) (20 (LESSTHEQ) x (LESSTHEQ) 100), Fe(,x)Nb(,100 -x) (22 (LESSTHEQ) x (LESSTHEQ) 85), Ni(,x)Nb(,100-x) (20 (LESSTHEQ) x (LESSTHEQ) 80), Cu(,x)Nb(,100-x) (10 (LESSTHEQ) x (LESSTHEQ) 90) were studied over a wide composition range. Films were made using a magnetron sputtering system, and the structure of the films was investigated by energy dispersive x-ray diffraction. The composition region of each amorphous alloys system was determined and found in good agreement with a model proposed by Egami and Waseda. The magnetic properties and hyperfine interactions in the films were investigated using a conventional Mossbauer spectrometer and a ('57)Co in Rh matrix source. In all Fe-early transition metal binary alloys systems, Fe does not retain its moment in the low iron concentration region and the result is that the critical concentration for magnetic order (x(,c)) is much larger than anticipated from percolation considerations. A direct comparison between crystalline alloys and their amorphous counterparts of the same composition illustrate no clear correlation between crystalline and amorphous states. Pronounced discontinuities in the magnetic properties with variation in Fe content of all Fe-early transition metal alloys at phase boundaries separating amorphous and crystalline states have been observed. This is caused by the differences in the atomic arrangement and the electronic structure between crystalline and amorphous solids. The temperature dependence of resistivity, (rho)(T), of several binary amorphous alloys of Fe-TM (where TM = Ti, Zr, Hf, Nb etc.) has been studied from 2K to 300K. The Fe-poor (x < x(,c)) samples and the Fe-rich (x > x(,c)) samples have distinctive differences in (rho)(T) at low temperature

  13. 50 CFR 224.105 - Speed restrictions to protect North Atlantic Right Whales.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Speed restrictions to protect North... AND ANADROMOUS SPECIES § 224.105 Speed restrictions to protect North Atlantic Right Whales. (a) The..., GA): Vessels shall travel at a speed of 10 knots or less over ground during the period of November 15...

  14. 50 CFR 224.105 - Speed restrictions to protect North Atlantic Right Whales.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Speed restrictions to protect North... AND ANADROMOUS SPECIES § 224.105 Speed restrictions to protect North Atlantic Right Whales. (a) The..., GA): Vessels shall travel at a speed of 10 knots or less over ground during the period of November 15...

  15. 41 CFR 302-3.224 - If I violate my new service agreement, will the Government reimburse me for return travel and...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false If I violate my new... place of residence? 302-3.224 Section 302-3.224 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Types...

  16. 41 CFR 302-3.224 - If I violate my new service agreement, will the Government reimburse me for return travel and...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false If I violate my new... place of residence? 302-3.224 Section 302-3.224 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Types...

  17. 41 CFR 302-3.224 - If I violate my new service agreement, will the Government reimburse me for return travel and...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false If I violate my new... place of residence? 302-3.224 Section 302-3.224 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Types...

  18. 41 CFR 302-3.224 - If I violate my new service agreement, will the Government reimburse me for return travel and...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false If I violate my new... place of residence? 302-3.224 Section 302-3.224 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Types...

  19. 41 CFR 302-3.224 - If I violate my new service agreement, will the Government reimburse me for return travel and...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true If I violate my new... place of residence? 302-3.224 Section 302-3.224 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Types...

  20. MiR-224 Targets the 3′UTR of Type 1 5′-Iodothyronine Deiodinase Possibly Contributing to Tissue Hypothyroidism in Renal Cancer

    PubMed Central

    Boguslawska, Joanna; Wojcicka, Anna; Piekielko-Witkowska, Agnieszka; Master, Adam; Nauman, Alicja

    2011-01-01

    Type 1 iodothyronine deiodinase (DIO1) catalyses the conversion of prohormone thyroxine to the active thyroid hormone 3,3′,5-triiodothyronine (T3), important regulator of cell proliferation and differentiation. DIO1 expression is reduced in the most common type of kidney neoplasia, clear cell Renal Cell Carcinoma (ccRCC). MicroRNAs are small, non-coding RNAs that regulate gene expression at posttranscriptional levels. The aim of this study was to analyze the potential regulation of DIO1 expression by microRNAs in ccRCC. Bioinformatic analysis revealed that 3′UTR of the human DIO1 gene transcript contains miR-224 and miR-383 target sites, which are conserved across mammalian species. Semi-quantitative real-time PCR was used to analyze the expression of miR-224 and miR-383 in 32 samples of ccRCC tumors (T) and in 32 matched control (C) samples. We observed statistically significant (p = 0.0002) more than four fold increase in miR-224 expression and nearly two fold increase in miR-383 expression in samples T compared to samples C. Tumor specific changes in expression of miR-224 negatively correlated with changes in DIO1 expression and intracellular T3 concentration. Transfection of HeLa cell line with miR-224 and miR-383 suppressed the activity of a luciferase reporter containing the 3′UTR of DIO1. This was abolished when constructs mutated at the miR-224 and miR-383 target sites were used instead, indicating that miR-224 and miR-383 directly bind to DIO1 3′UTR. Finally, induced expression of miR-224 in Caki-2 cells resulted in significant (p<0.01) reduction of DIO1 mRNA. This study provides a novel miRNA-mediated regulatory mechanism of DIO1 expression in ccRCC. PMID:21912701

  1. Thermal affected zone obtained in machining steel XC42 by high-power continuous CO 2 laser

    NASA Astrophysics Data System (ADS)

    Jebbari, Neila; Jebari, Mohamed Mondher; Saadallah, Faycal; Tarrats-Saugnac, Annie; Bennaceur, Raouf; Longuemard, Jean Paul

    2008-09-01

    A high-power continuous CO 2 laser (4 kW) can provide energy capable of causing melting or even, with a special treatment of the surface, vaporization of an XC42-steel sample. The laser-metal interaction causes an energetic machining mechanism, which takes place according to the assumption that the melting front precedes the laser beam, such that the laser beam interacts with a preheated surface whose temperature is near the melting point. The proposed model, obtained from the energy balance during the interaction time, concerns the case of machining with an inert gas jet and permits the calculation of the characteristic parameters of the groove according to the characteristic laser parameters (absorbed laser energy and impact diameter of the laser beam) and allows the estimation of the quantity of the energy causing the thermal affected zone (TAZ). This energy is equivalent to the heat quantity that must be injected in the heat propagation equation. In the case of a semi-infinite medium with fusion temperature at the surface, the resolution of the heat propagation equation gives access to the width of the TAZ.

  2. 25 CFR 224.137 - What must the Director do if a tribe's noncompliance has resulted in harm or the potential for...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... resulted in harm or the potential for harm to a physical trust asset? 224.137 Section 224.137 Indians... AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Periodic Reviews... potential for harm to a physical trust asset? If, because of the tribe's noncompliance with Federal law or...

  3. Ferromagnetic resonance investigation in as-prepared NiFe/FeMn/NiFe trilayer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yuan, S. J.; Xu, K.; Yu, L. M.

    2007-06-01

    NiFe/FeMn/NiFe trilayer prepared by dc magnetron sputtering was systematically investigated by ferromagnetic resonance technique (FMR) at room temperature. For NiFe/FeMn/NiFe trilayer, there are two distinct resonance peaks both in in-plane and out-of-plane FMR spectra, which are attributed to the two NiFe layers, respectively. The isotropic in-plane resonance field shift is negative for the bottom NiFe layer, while positive for the top NiFe layer. And, such phenomena result from the negative interfacial perpendicular anisotropy at the bottom NiFe/FeMn interface and positive interfacial perpendicular anisotropy at the top FeMn/NiFe interface. The linewidth of the bottom NiFe layer is larger than that ofmore » the top NiFe layer, which might be related to the greater exchange coupling at the bottom NiFe/FeMn interface.« less

  4. 25 CFR 224.84 - When may a tribe grant a right-of-way?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....84 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Implementation of Tribal Energy Resource Agreements Leases, Business Agreements, and Rights-Of-Way Under A Tera § 224.84...

  5. 25 CFR 224.84 - When may a tribe grant a right-of-way?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....84 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Implementation of Tribal Energy Resource Agreements Leases, Business Agreements, and Rights-Of-Way Under A Tera § 224.84...

  6. Corrective Action Decision Document for Corrective Action Unit 224: Decon Pad and Septic Systems Nevada Test Site, Nevada, Rev. No.: 0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David A. Strand

    2005-05-01

    This Corrective Action Decision Document has been prepared for Corrective Action Unit (CAU) 224, Decon Pad and Septic Systems, in Areas 2, 3, 5, 6, 11, and 23 of the Nevada Test Site, Nevada, in accordance with the ''Federal Facility Agreement and Consent Order'' (1996). Corrective Action Unit 224 is comprised of the following corrective action sites (CASs): (1) 02-04-01, Septic Tank (Buried); (2) 03-05-01, Leachfield; (3) 05-04-01, Septic Tanks (4)/Discharge Area; (4) 06-03-01, Sewage Lagoons (3); (5) 06-05-01, Leachfield; (6) 06-17-04, Decon Pad and Wastewater Catch; (7) 06-23-01, Decon Pad Discharge Piping; (8) 11-04-01, Sewage Lagoon; and (9) 23-05-02,more » Leachfield. The purpose of this Corrective Action Decision Document is to identify and provide the rationale for the recommendation of a corrective action alternative for the nine CASs within CAU 224. Corrective action investigation activities were performed from August 10, 2004, through January 18, 2005, as set forth in the CAU 224 Corrective Action Investigation Plan.« less

  7. Synthetic, Infrared, 1Hand 13CNMR Spectral Studies on N-(p-Substituted Phenyl)-p-Substituted Benzenesulphonamides, p-X'C6H4SO2NH- (p-XC6H4), where X' or X = H, CH3, C2H5, F, Cl or Br

    NASA Astrophysics Data System (ADS)

    Gowda, B. Thimme; Jayalakshmi, K. L.; Shetty, Mahesha

    2004-05-01

    Thirty N-(p-substituted phenyl)-p-substituted benzenesulphonamides of the general formula, p-X'C6H4SO2NH(p-XC6H4), where X' or X = H, CH3, C2H5, F, Cl or Br, are synthesised and their infrared spectra in the solid state and 1H and 13C NMR spectra in solution are measured. The N-H stretching vibrational frequencies, νN-H vary in the range 3334 - 3219 cm-1, while the asymmetric and symmetric SO2 vibrations appear in the ranges 1377 - 1311 cm-1 and 1182 - 1151 cm-1, respectively. The compounds exhibit S-N and C-N stretching vibrational absorptions in the ranges 937 - 898 cm-1 and 1310 - 1180 cm-1, respectively. There are no particular trends in the variation of these frequencies on substitution with either electron withdrawing or electron donating groups. The 1H and 13C chemical shifts of N-(p-substituted phenyl)-p-substituted benzenesulphonamides, are assigned to various protons and carbons of the two benzene rings. Further, incremental shifts of the ring protons and carbons due to -SO2NH(p-XC6H4) groups in the compounds of the formula, C6H5SO2NH(p-XC6H4), and p-X'C6H4SO2- and p-X'C6H4SO2NH- groups in the compounds of the formula, p-X'C6H4SO2NH(C6H5) are computed and used to calculate the 1H and 13C chemical shifts of the parallely substituted compounds of the general formula p-X'C6H4SO2NH(p-XC6H4). The computed values agree well with the observed chemical shifts. The above incremental shifts are found to correlate with the Hammett substituent parameters.

  8. [FeFe]- and [NiFe]-hydrogenase diversity, mechanism, and maturation.

    PubMed

    Peters, John W; Schut, Gerrit J; Boyd, Eric S; Mulder, David W; Shepard, Eric M; Broderick, Joan B; King, Paul W; Adams, Michael W W

    2015-06-01

    The [FeFe]- and [NiFe]-hydrogenases catalyze the formal interconversion between hydrogen and protons and electrons, possess characteristic non-protein ligands at their catalytic sites and thus share common mechanistic features. Despite the similarities between these two types of hydrogenases, they clearly have distinct evolutionary origins and likely emerged from different selective pressures. [FeFe]-hydrogenases are widely distributed in fermentative anaerobic microorganisms and likely evolved under selective pressure to couple hydrogen production to the recycling of electron carriers that accumulate during anaerobic metabolism. In contrast, many [NiFe]-hydrogenases catalyze hydrogen oxidation as part of energy metabolism and were likely key enzymes in early life and arguably represent the predecessors of modern respiratory metabolism. Although the reversible combination of protons and electrons to generate hydrogen gas is the simplest of chemical reactions, the [FeFe]- and [NiFe]-hydrogenases have distinct mechanisms and differ in the fundamental chemistry associated with proton transfer and control of electron flow that also help to define catalytic bias. A unifying feature of these enzymes is that hydrogen activation itself has been restricted to one solution involving diatomic ligands (carbon monoxide and cyanide) bound to an Fe ion. On the other hand, and quite remarkably, the biosynthetic mechanisms to produce these ligands are exclusive to each type of enzyme. Furthermore, these mechanisms represent two independent solutions to the formation of complex bioinorganic active sites for catalyzing the simplest of chemical reactions, reversible hydrogen oxidation. As such, the [FeFe]- and [NiFe]-hydrogenases are arguably the most profound case of convergent evolution. This article is part of a Special Issue entitled: Fe/S proteins: Analysis, structure, function, biogenesis and diseases. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Products and mechanism of the reaction of OH radicals with 2,2,4-trimethylpentane in the presence of NO.

    PubMed

    Aschmann, Sara M; Arey, Janet; Atkinson, Roger

    2002-02-15

    Alkanes are important constituents of gasoline fuel and vehicle exhaust, with branched alkanes comprising a significant fraction of the total alkanes observed in urban areas. Products of the gas-phase reactions of OH radicals with 2,2,4-trimethylpentane and 2,2,4-trimethylpentane-d18 in the presence of NO at 298+/-2 K and atmospheric pressure of air have been investigated using gas chromatography with flame ionization detection (GC-FID), combined gas chromatography-mass spectrometry (GC-MS), and in situ atmospheric pressure ionization tandem mass spectrometry (API-MS). Acetone, 2-methylpropanal, and 4-hydroxy-4-methyl-2-pentanone were identified and quantified by GC-FID from 2,2,4-trimethylpentane with molar formation yields of 54+/-7%, 26+/-3%, and 5.1+/-0.6%, respectively; upper limits to the formation yields of acetaldehyde, 2,2-dimethylpropanal, and 4,4-dimethyl-2-pentanone were obtained. Additional products observed from 2,2,4-trimethylpentane by API-MS and API-MS/MS analyses using positive and negative ion modes were hydroxy products of molecular weight 130 and 144, a product of molecular weight 128 (attributed to a C8-carbonyl), and hydroxynitrates of molecular weight 135, 177, and 191 (attributed to HOC4H8ONO2, HOC7H14ONO2, and HOC8H16-ONO2, respectively). Formation of HOC8H16ONO2 and HOC7H14-ONO2 is consistent with the observation of products of molecular weight 207 (HOC8D16ONO2) and 191 (HOC7D14-ONO2), respectively, in the API-MS analyses of the 2,2,4-trimethylpentane-d18 reaction (-OD groups rapidly exchange to -OH groups under our experimental conditions). These product data allow the reaction pathways to be delineated to a reasonable extent, and the reaction mechanism is discussed.

  10. Effect of dopants on the soft magnetic properties and high frequency characteristics of FeCoBM (M = Ti, Nb, Hf, and Ta) thin films.

    PubMed

    Hsieh, C C; Lin, T H; Chang, H W; Chang, C W; Chang, W C; Yang, C C

    2011-03-01

    Effect of dopants on the soft magnetic properties and high frequency characteristics of FeCoBM thin films (M = Ti, Nb, Hf, and Ta) have been studied. For (Fe0.55Co0.45)(100-x)B(x) (x = 5-15) thin films, with the increase of B content, the resistivity was increased because B could decrease the crystallinity of the films. The (Fe0.55Co0.45)90B10 thin film showed the optimum properties, where 4piM(s) = 16.1 kG, H(ce) = 64.2 Oe, H(ch) = 13.5 Oe, H(k) = 310 Oe and p = 338 microomega-cm. To reduce the coercivity of the film, the elements M, including Ti, Nb, Hf, and Ta, were selected to substitute for B in the FeCoB films. It was found that (Fe0.55Co0.45)90B6Ti2Nb2 thin film after annealing at a temperature of 200 degrees C for 30 min showed the optimal properties, where 4piM(s) = 15.8 kG, H(ce) = 4.8 Oe, H(ch) = 3.6 Oe, H(k) = 224 Oe and p = 290 microomega-cm. The theoretically calculated ferromagnetic resonance frequency of the developed films can be higher than 5 GHz.

  11. 25 CFR 224.136 - How will the Director's report address a tribe's noncompliance?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DETERMINATION ACT Periodic Reviews Noncompliance § 224.136 How will the Director's report address a tribe's noncompliance? This section applies if the Director conducts a review and evaluation or investigation of a... determination of whether the tribe's noncompliance has resulted in harm or the potential for harm to a physical...

  12. MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms

    PubMed Central

    Amankwatia, E B; Chakravarty, P; Carey, F A; Weidlich, S; Steele, R J C; Munro, A J; Wolf, C R; Smith, G

    2015-01-01

    Background: Colorectal cancers arise from benign adenomas, although not all adenomas progress to cancer and there are marked interpatient differences in disease progression. We have previously associated KRAS mutations with disease progression and reduced survival in colorectal cancer patients. Methods: We used TaqMan low-density array (TLDA) qRT–PCR analysis to identify miRNAs differentially expressed in normal colorectal mucosa, adenomas and cancers and in isogeneic KRAS WT and mutant HCT116 cells, and used a variety of phenotypic assays to assess the influence of miRNA expression on KRAS activity, chemosensitivity, proliferation and invasion. Results: MicroRNA-224 was differentially expressed in dysplastic colorectal disease and in isogeneic KRAS WT and mutant HCT116 cells. Antagomir-mediated miR-224 silencing in HCT116 KRAS WT cells phenocopied KRAS mutation, increased KRAS activity and ERK and AKT phosphorylation. 5-FU chemosensitivity was significantly increased in miR-224 knockdown cells, and in NIH3T3 cells expressing KRAS and BRAF mutant proteins. Bioinformatics analysis of predicted miR-224 target genes predicted altered cell proliferation, invasion and epithelial–mesenchymal transition (EMT) phenotypes that were experimentally confirmed in miR-224 knockdown cells. Conclusions: We describe a novel mechanism of KRAS regulation, and highlight the clinical utility of colorectal cancer-specific miRNAs as disease progression or clinical response biomarkers. PMID:25919696

  13. High performance binder-free SiO x/C composite LIB electrode made of SiO x and lignin

    DOE PAGES

    Chen, Tao; Hu, Jiazhi; Zhang, Long; ...

    2017-07-19

    A high performance binder-free SiO x/C composite electrode was synthesized by mixing SiO x particles and Kraft lignin in a cryo-mill followed by heat treatment at 600 °C. After the heat treatment, lignin formed a conductive matrix hosting SiO x particles, ensuring electronic conductivity, connectivity, and accommodation of volume changes during lithiation/delithiation. As the result, no conventional binder or conductive agent was necessary. When electrochemically cycled, the composite electrode delivered excellent performance, maintaining ~900 mAh g -1 after 250 cycles at a rate of 200 mA g -1, and good rate capability. The robustness of the electrode was also examinedmore » by post-cycling SEM images, where few cracks were observed. The excellent electrochemical performance can be attributed to the comparatively small volume change of SiO x-based electrodes (160%) and the flexibility of the lignin derived carbon matrix to accommodate the volume change. In conclusion, this work should stimulate further interests in using bio-renewable resources in making advanced electrochemical energy storage systems.« less

  14. High performance binder-free SiO x/C composite LIB electrode made of SiO x and lignin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Tao; Hu, Jiazhi; Zhang, Long

    A high performance binder-free SiO x/C composite electrode was synthesized by mixing SiO x particles and Kraft lignin in a cryo-mill followed by heat treatment at 600 °C. After the heat treatment, lignin formed a conductive matrix hosting SiO x particles, ensuring electronic conductivity, connectivity, and accommodation of volume changes during lithiation/delithiation. As the result, no conventional binder or conductive agent was necessary. When electrochemically cycled, the composite electrode delivered excellent performance, maintaining ~900 mAh g -1 after 250 cycles at a rate of 200 mA g -1, and good rate capability. The robustness of the electrode was also examinedmore » by post-cycling SEM images, where few cracks were observed. The excellent electrochemical performance can be attributed to the comparatively small volume change of SiO x-based electrodes (160%) and the flexibility of the lignin derived carbon matrix to accommodate the volume change. In conclusion, this work should stimulate further interests in using bio-renewable resources in making advanced electrochemical energy storage systems.« less

  15. Mercury flux from salt marsh sediments: Insights from a comparison between 224Ra/228Th disequilibrium and core incubation methods

    NASA Astrophysics Data System (ADS)

    Shi, Xiangming; Mason, Robert P.; Charette, Matthew A.; Mazrui, Nashaat M.; Cai, Pinghe

    2018-02-01

    In aquatic environments, sediments are the main location of mercury methylation. Thus, accurate quantification of methylmercury (MeHg) fluxes at the sediment-water interface is vital to understanding the biogeochemical cycling of mercury, especially the toxic MeHg species, and their bioaccumulation. Traditional approaches, such as core incubations, are difficult to maintain at in-situ conditions during assays, leading to over/underestimation of benthic fluxes. Alternatively, the 224Ra/228Th disequilibrium method for tracing the transfer of dissolved substances across the sediment-water interface, has proven to be a reliable approach for quantifying benthic fluxes. In this study, the 224Ra/228Th disequilibrium and core incubation methods were compared to examine the benthic fluxes of both 224Ra and MeHg in salt marsh sediments of Barn Island, Connecticut, USA from May to August, 2016. The two methods were comparable for 224Ra but contradictory for MeHg. The radiotracer approach indicated that sediments were always the dominant source of both total mercury (THg) and MeHg. The core incubation method for MeHg produced similar results in May and August, but an opposite pattern in June and July, which suggested sediments were a sink of MeHg, contrary to the evidence of significant MeHg gradients between overlying water and porewater at the sediment-water interface. The potential reasons for such differences are discussed. Overall, we conclude that the 224Ra/228Th disequilibrium approach is preferred for estimating the benthic flux of MeHg and that sediment is indeed an important MeHg source in this marshland, and likely in other shallow coastal waters.

  16. Comparison of Ab initio Low-Energy Models for LaFePO, LaFeAsO, BaFe2As2, LiFeAs, FeSe, and FeTe

    NASA Astrophysics Data System (ADS)

    Nakamura, Kazuma; Miyake, Takashi; Arita, Ryotaro; Imada, Masatoshi

    2010-03-01

    We present effective low-energy models for LaFePO and LaFeAsO (1111 family), BaFe2As2 (122), LiFeAs (111), and FeSe and FeTe (11) [1], based on ab initio downfolding scheme, a constrained random-phase-approximation method combined with maximally localized Wannier functions. Comparison among the effective models, derived for 5 Fe-3d bands, provides a basis for interpreting physics/chemistry; material dependences of electron correlations, a multiband character entangled by the 3d orbitals, and the geometrical frustration depending on hybridizations between iron and pnictogen/chalcogen orbitals. We found that LaFePO in the 1111 family resides in the weak correlation regime, while LaFeAsO and 111/122 compounds are the intermediate region and FeSe and FeTe in the 11 family are located in the strong correlation regime. A principal parameter relevant to the physics is clarified to be the pnictogen/chalcogen height from the iron layer. Implications in low-energy properties including magnetism and superconductivity are discussed. [1] T. Miyake, K. Nakamura, R. Arita, and M. Imada, arXiv:0911.3705.

  17. IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR 2,2,4-TRIMETHYLPENTANE (EXTERNAL REVIEW DRAFT)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 2,2,4-trimethylpentane, also called TMP, that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that scie...

  18. 31 CFR 224.7 - Where can I find a list of United States district court offices?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.7 Where can I find a list of United States district...

  19. 31 CFR 224.7 - Where can I find a list of United States district court offices?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.7 Where can I find a list of United States district...

  20. 31 CFR 224.7 - Where can I find a list of United States district court offices?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.7 Where can I find a list of United States district...

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