Phylogenetic analysis of Newcastle disease viruses from Bangladesh suggests continuing evolution of genotype XIII.

PubMed

Barman, Lalita Rani; Nooruzzaman, Mohammed; Sarker, Rahul Deb; Rahman, Md Tazinur; Saife, Md Rajib Bin; Giasuddin, Mohammad; Das, Bidhan Chandra; Das, Priya Mohan; Chowdhury, Emdadul Haque; Islam, Mohammad Rafiqul

2017-10-01

A total of 23 Newcastle disease virus (NDV) isolates from Bangladesh taken between 2010 and 2012 were characterized on the basis of partial F gene sequences. All the isolates belonged to genotype XIII of class II NDV but segregated into three sub-clusters. One sub-cluster with 17 isolates aligned with sub-genotype XIIIc. The other two sub-clusters were phylogenetically distinct from the previously described sub-genotypes XIIIa, XIIIb and XIIIc and could be candidates of new sub-genotypes; however, that needs to be validated through full-length F gene sequence data. The results of the present study suggest that genotype XIII NDVs are under continuing evolution in Bangladesh.

Impact of combined C1 esterase inhibitor/coagulation factor XIII or N-acetylcysteine/tirilazad mesylate administration on leucocyte adherence and cytokine release in experimental endotoxaemia.

PubMed

Birnbaum, J; Klotz, E; Spies, C D; Mueller, J; Vargas Hein, O; Feller, J; Lehmann, C

2008-01-01

We determined the effects of combinations of C1 esterase inhibitor (C1-INH) with factor XIII and of N-acetylcysteine (NAC) with tirilazad mesylate (TM) during lipo-polysaccharide (LPS)-induced endotoxaemia in rats. Forty Wistar rats were divided into four groups: the control (CON) group received no LPS; the LPS, C1-INH + factor XIII and NAC + TM groups received endotoxin infusions (5 mg/kg per h). After 30 min of endotoxaemia, 100 U/kg C1-INH + 50 U/kg factor XIII was administered to the C1-INH + factor XIII group, and 150 mg/kg NAC + 10 mg/kg TM was administered in the NAC + TM group. Administration of C1-INH + factor XIII and NAC + TM both resulted in reduced leucocyte adherence and reduced levels of interleukin-1beta (IL-1beta). The LPS-induced increase in IL-6 levels was amplified by both drug combinations. There was no significant effect on mesenteric plasma extravasation. In conclusion, the administration of C1-INH + factor XIII and NAC + TM reduced endothelial leucocyte adherence and IL-1beta plasma levels, but increased IL-6 levels.

Dirac R-matrix calculations of photoionization cross sections of Ni XII and atomic structure data of Ni XIII

NASA Astrophysics Data System (ADS)

Nazir, R. T.; Bari, M. A.; Bilal, M.; Sardar, S.; Nasim, M. H.; Salahuddin, M.

2017-02-01

We performed R-matrix calculations for photoionization cross sections of the two ground state configuration 3s23p5 (^2P^o3/2,1/2) levels and 12 excited states of Ni XII using relativistic Dirac Atomic R-matrix Codes (DARC) across the photon energy range between the ionizations thresholds of the corresponding states and well above the thresholds of the last level of the Ni XIII target ion. Generally, a good agreement is obtained between our results and the earlier theoretical photoionization cross sections. Moreover, we have used two independent fully relativistic GRASP and FAC codes to calculate fine-structure energy levels, wavelengths, oscillator strengths, transitions rates among the lowest 48 levels belonging to the configuration (3s23p4, 3s3p5, 3p6, 3s23p33d) in Ni XIII. Additionally, radiative lifetimes of all the excited states of Ni XIII are presented. Our results of the atomic structure of Ni XIII show good agreement with other theoretical and experimental results available in the literature. A good agreement is found between our calculated lifetimes and the experimental ones. Our present results are useful for plasma diagnostic of fusion and astrophysical plasmas.

Traffic analysis toolbox volume XIII : integrated corridor management analysis, modeling, and simulation guide

DOT National Transportation Integrated Search

2017-02-01

As part of the Federal Highway Administration (FHWA) Traffic Analysis Toolbox (Volume XIII), this guide was designed to help corridor stakeholders implement the Integrated Corridor Management (ICM) Analysis, Modeling, and Simulation (AMS) methodology...

Traffic analysis toolbox volume XIII : integrated corridor management analysis, modeling, and simulation guide.

DOT National Transportation Integrated Search

2017-02-01

As part of the Federal Highway Administration (FHWA) Traffic Analysis Toolbox (Volume XIII), this guide was designed to help corridor stakeholders implement the Integrated Corridor Management (ICM) Analysis, Modeling, and Simulation (AMS) methodology...

40 CFR Appendix Xiii to Part 86 - State Requirements Incorporated by Reference in Part 86 of the Code of Federal Regulations

Code of Federal Regulations, 2012 CFR

2012-07-01

... AND IN-USE HIGHWAY VEHICLES AND ENGINES (CONTINUED) Pt. 86, App. XIII Appendix XIII to Part 86—State...-Line Test Procedures for 1983 Through 1997 Model-Year Passenger Cars, Light-Duty Trucks and Medium-Duty...: California Assembly-Line Test Procedures for 1998 and Subsequent Model-Year Passenger Cars, Light-Duty Trucks...

40 CFR Appendix Xiii to Part 86 - State Requirements Incorporated by Reference in Part 86 of the Code of Federal Regulations

Code of Federal Regulations, 2013 CFR

2013-07-01

... AND IN-USE HIGHWAY VEHICLES AND ENGINES (CONTINUED) Pt. 86, App. XIII Appendix XIII to Part 86—State...-Line Test Procedures for 1983 Through 1997 Model-Year Passenger Cars, Light-Duty Trucks and Medium-Duty...: California Assembly-Line Test Procedures for 1998 and Subsequent Model-Year Passenger Cars, Light-Duty Trucks...

40 CFR Appendix Xiii to Part 86 - State Requirements Incorporated by Reference in Part 86 of the Code of Federal Regulations

Code of Federal Regulations, 2011 CFR

2011-07-01

... AND IN-USE HIGHWAY VEHICLES AND ENGINES (CONTINUED) Pt. 86, App. XIII Appendix XIII to Part 86—State...-Line Test Procedures for 1983 Through 1997 Model-Year Passenger Cars, Light-Duty Trucks and Medium-Duty...: California Assembly-Line Test Procedures for 1998 and Subsequent Model-Year Passenger Cars, Light-Duty Trucks...

[Best time to administer coagulation factor XIII( Fibrogammin P) for postoperative intractable pancreatic fistula following gastrectomy for gastric cancer].

PubMed

Shoda, Katsutoshi; Komatsu, Shuhei; Ichikawa, Daisuke; Kubota, Takeshi; Okamoto, Kazuma; Arita, Tomohiro; Konishi, Hirotaka; Murayama, Yasutoshi; Shiozaki, Atsushi; Kuriu, Yoshiaki; Ikoma, Hisashi; Nakanishi, Masayoshi; Fujiwara, Hitoshi; Otsuji, Eigo

2013-11-01

Coagulation factor XIII( Fibrogammin P, F XIII) has been used to treat postoperative pancreatic fistulas following gastrectomy for gastric cancer in Japan. However, little is known about the best timing to start this treatment for early recovery. This study was designed to examine the appropriate time to start Fibrogammin P treatment for pancreatic fistulas, based on nutritional and inflammatory parameters. We retrospectively examined 27 consecutive patients with Grade B or C pancreatic fistulas as defined by the International Study Group of Pancreatic Fistula( ISGPF) classification who underwent gastrectomy at our institute between 1997 and 2011. We analyzed data on total protein( TP), albumin (Alb), C-reactive protein( CRP), and hemoglobin( Hb) concentrations and white blood cell( WBC) and lymphocyte counts. We used this information to determine laboratory cut-off values that indicate the most advantageous time to start the administration of Fibrogammin P in order to achieve early recovery within 2 weeks. When Fibrogammin P administration was based on more than 2 cut-off values such as Alb>2.6 g/dL and Hb>9.0 g/dL and WBC<9,000/μL (p= 0.1563), early cure of pancreatic fistulas was achieved. The use of nutritional and inflammatory parameter values to determine the best time to administer Fibrogammin P may shorten the treatment period.

FE-XIII Infrared / FE-XIV Green Line Ratio Diagnostics (P55)

NASA Astrophysics Data System (ADS)

Srivastava, A. K.; et al.

2006-11-01

aks.astro.itbhu@gmail.com We consider the first 27-level atomic model of Fe XIII (5.9 < log Te < 6.4 K) to estimate its ground level populations, taking account of electron as well as proton collisional excitations and de-excitations, radiative cascades, radiative excitations and de-excitations. Radiative cascade is important but the effect of dilution factor is negligible at higher electron densities. The 3 P1-3P0 and 3P2-3P1 transitions in the ground configuration 3s2 3p2 of Fe XIII result in two forbidden coronal emission lines in the infrared region, namely 10747 Å and 10798 Å., while the 5303 Å green line is formed in the 3s2 3p 2 2 ground configuration of Fe XIV as a result of P3 / 2 - P1 / 2 magnetic dipole transition. The line-widths of appropriate pair of forbidden coronal emission lines observed simultaneously can be useful diagnostic tool to deduce temperature and non-thermal velocity in the large scale coronal structures using intensity ratios of the lines as the temperature signature, instead of assuming ion temperature to be equal to the electron temperature. Since the line intensity ratios IG5303/IIR10747 and IG5303/IIR10798 have very week density dependence, they are ideal monitors of temperature mapping in the solar corona.

Newly-recognized roles of factor XIII in thrombosis

PubMed Central

Byrnes, James R.; Wolberg, Alisa S.

2017-01-01

Arterial and venous thrombosis are major contributors to coagulation-associated morbidity and mortality. Greater understanding of mechanisms leading to thrombus formation and stability is expected to lead to improved treatment strategies. Factor XIII (FXIII) is a transglutaminase found in plasma and platelets. During thrombosis, activated FXIII crosslinks fibrin and promotes thrombus stability. Recent studies have provided new information about FXIII activity during coagulation and its effects on clot composition and function. These findings reveal newly-recognized roles for FXIII in thrombosis. Herein, we review published literature on FXIII biology and effects on fibrin structure and stability, epidemiologic data associating FXIII with thrombosis, and evidence from animal models indicating FXIII has an essential role in determining thrombus stability, composition, and size. PMID:27056150

Free factor XIII activation peptide (fAP-FXIII) is a regulator of factor XIII activity via factor XIII-B.

PubMed

Dodt, Johannes; Pasternack, Ralf; Seitz, Rainer; Volkers, Peter

2016-02-01

In a factor XIIIa (FXIIIa) generation assay with recombinant FXIII-A2 (rFXIII-A2 ) free FXIII activation peptide (fAP-FXII) prolonged the time to peak (TTP) but did not affect the area under the curve (AUC) or concentration at peak (CP). Addition of recombinant factorXIII-B2 (rFXIII-B2 ) restored the characteristics of the FXIIIa generation parameters (AUC, TTP and CP) to those observed for plasma FXIII (FXIII-A2 B2 ). FXIII-A2 B2 reconstituted from rFXIII-A2 and rFXIII-B2 showed a similar effect on AUC, TTP and CP in the presence of fAP-FXII as observed for plasma FXIII-A2 B2 , indicating a role for FXIII-B in this observation. An effect of fAP-FXIII on thrombin, the proteolytic activator of FXIII, was excluded by thrombin generation assays and clotting experiments. In a purified system, fAP-FXIII did not interfere with the FXIIIa activity development of thrombin-cleaved rFXIII-A2 (rFXIII-A2 ') also excluding direct inhibition of FXIIIa. However, FXIIIa activity development of FXIII-A2 'B2 was inhibited in a concentration-dependent manner by fAP-FXIII, indicating that an interaction between AP-FXIII and FXIII-B2 contributes to the overall stability of FXIII-A2 'B2 . In addition to its well-known role, FXIII-B also contributes to FXIII-A2 B2 stability or dissociation depending on fAP-FXIII and calcium concentrations. © 2015 John Wiley & Sons Ltd.

Raman spectroscopic study of hydrogen ordered ice XIII and of its reversible phase transition to disordered ice V.

PubMed

Salzmann, Christoph G; Hallbrucker, Andreas; Finney, John L; Mayer, Erwin

2006-07-14

Raman spectra of recovered ordered H(2)O (D(2)O) ice XIII doped with 0.01 M HCl (DCl) recorded in vacuo at 80 K are reported in the range 3600-200 cm(-1). The bands are assigned to the various types of modes on the basis of isotope ratios. On thermal cycling between 80 and 120 K, the reversible phase transition to disordered ice V is observed. The remarkable effect of HCl (DCl) on orientational ordering in ice V and its phase transition to ordered ice XIII, first reported in a powder neutron diffraction study of DCl doped D(2)O ice V (C. G. Salzmann, P. G. Radaelli, A. Hallbrucker, E. Mayer, J. L. Finney, Science, 2006, 311, 1758), is demonstrated by Raman spectroscopy and discussed. The dopants KOH and HF have only a minor effect on hydrogen ordering in ice V, as shown by the Raman spectra.

PREFACE: XIII International Conference on Calorimetry in High Energy Physics (CALOR 2008)

NASA Astrophysics Data System (ADS)

Livan, Michele

2009-07-01

The XIII International Conference on Calorimetry in High Energy Physics was held in Pavia, Italy, 26-30 May 2008, picking up the baton from the 2006 Conference in Chicago. The Conference took place in the unique environment of the Theresian Room of the University Library. The attendees were surrounded by over 40 000 books of general interest and culture, and had the opportunity to see precious volumes written by such people as Galileo, Volta and Faraday. The Workshop brought together more than 120 participants, including senior scientists as well as young physicists, confirming the central and ever-growing role of calorimeters in modern particle physics. The development of these detectors, as stressed by Professor Klaus Pretzl in his lectio magistralis, has made it possible to explore new frontiers in physics, and the present scenario is no exception to this rule. With the LHC experiments almost completely installed and ready to take data, the Conference was an ideal chance to review the status of the different projects, whose development has been followed and discussed throughout the entire Calor series, and to show that they are capable of meeting the design specifications. Other highlights were the performance and physics results of calorimeters installed in currently operating experiments. In the session on astrophysics and neutrinos, the contributions confirmed the key role of calorimeters in this sector and demonstrated their growing application even beyond the field of accelerator physics. Considerable time was devoted to the state-of-the-art techniques in the design and operation of the detectors, while the session on simulation addressed the importance of a thorough understanding of the shower development to meet the demanding requirements of present experiments. Finally, on the R&D side, the particle flow and dual read-out concepts confronted the challenges issued by the next generation of experiments. This complex material was reviewed in 83

Agreement between factor XIII activity and antigen assays in measurement of factor XIII: A French multicenter study of 147 human plasma samples.

PubMed

Caron, C; Meley, R; Le Cam Duchez, V; Aillaud, M F; Lavenu-Bombled, C; Dutrillaux, F; Flaujac, C; Ryman, A; Ternisien, C; Lasne, D; Galinat, H; Pouplard, C

2017-06-01

Factor XIII (FXIII) deficiency is a rare hemorrhagic disorder whose early diagnosis is crucial for appropriate treatment and prophylactic supplementation in cases of severe deficiency. International guidelines recommend a quantitative FXIII activity assay as first-line screening test. FXIII antigen measurement may be performed to establish the subtype of FXIII deficiency (FXIIID) when activity is decreased. The aim of this multicenter study was to evaluate the analytical and diagnostic levels of performance of a new latex immunoassay, K-Assay ® FXIII reagent from Stago, for first-line measurement of FXIII antigen. Results were compared to those obtained with the Berichrom ® FXIII chromogenic assay for measurement of FXIII activity. Of the 147 patient plasma samples, 138 were selected for analysis. The accuracy was very good, with intercenter reproducibility close to 7%. Five groups were defined on FXIII activity level (<5% (n = 5), 5%-30% (n = 23), 30%-60% (n = 17), 60%-120% (n = 69), above 120% (n = 24)), without statistical differences between activity and antigen levels (P value >0.05). Correlation of the K-Assay ® with the Berichrom ® FXIII activity results was excellent (r = 0.919). Good agreement was established by the Bland and Altman method, with a bias of +9.4% on all samples, and of -1.4% for FXIII levels lower than 30%. One patient with afibrinogenemia showed low levels of Berichrom ® FXIII activity but normal antigen level and clot solubility as expected. The measurement of FXIII antigen using the K-Assay ® is a reliable first-line tool for detection of FXIII deficiency when an activity assay is not available. © 2017 John Wiley & Sons Ltd.

Factor XIII stiffens fibrin clots by causing fiber compaction.

PubMed

Kurniawan, N A; Grimbergen, J; Koopman, J; Koenderink, G H

2014-10-01

Factor XIII-induced cross-linking has long been associated with the ability of fibrin blood clots to resist mechanical deformation, but how FXIII can directly modulate clot stiffness is unknown. We hypothesized that FXIII affects the self-assembly of fibrin fibers by altering the lateral association between protofibrils. To test this hypothesis, we studied the cross-linking kinetics and the structural evolution of the fibers and clots during the formation of plasma-derived and recombinant fibrins by using light scattering, and the response of the clots to mechanical stresses by using rheology. We show that the lateral aggregation of fibrin protofibrils initially results in the formation of floppy fibril bundles, which then compact to form tight and more rigid fibers. The first stage is reflected in a fast (10 min) increase in clot stiffness, whereas the compaction phase is characterized by a slow (hours) development of clot stiffness. Inhibition of FXIII completely abrogates the slow compaction. FXIII strongly increases the linear elastic modulus of the clots, but does not affect the non-linear response at large deformations. We propose a multiscale structural model whereby FXIII-mediated cross-linking tightens the coupling between the protofibrils within a fibrin fiber, thus making the fiber stiffer and less porous. At small strains, fiber stiffening enhances clot stiffness, because the clot response is governed by the entropic elasticity of the fibers, but once the clot is sufficiently stressed, the modulus is independent of protofibril coupling, because clot stiffness is governed by individual protofibril stretching. © 2014 International Society on Thrombosis and Haemostasis.

EDITORIAL: XIII Mexican Workshop on Particles and Fields

NASA Astrophysics Data System (ADS)

Barranco, Juan; Contreras, Guillermo; Delepine, David; Napsuciale, Mauro

2012-08-01

Juan Barranco Physics Department, Guanajuato University, Loma del Bosque 103, col. Loma del Campestre, 37150, Leon (Mexico) jbarranc@fisica.ugto.mx Guillermo Contreras Departamento de Fisica Aplicada Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Merida (Mexico) jgcn@mda.cinvestav.mx David Delepine Physics Department, Guanajuato University, Loma del Bosque 103, col. Loma del Campestre, 37150, Leon (Mexico) delepine@fisica.ugto.mx Mauro Napsuciale Physics Department, Guanajuato University, Loma del Bosque 103, col. Loma del Campestre, 37150, Leon (Mexico) mauro@fisica.ugto.mx The XIII Mexican Workshop on Particles and Fields (MWPF) took place from 20-26 October 2011, in the city of León, Guanajuato, México. This is a biennial meeting organized by the Division of Particles and Fields of the Mexican Physical Society designed to gather specialists in different areas of high energy physics to discuss the latest developments in the field. The thirteenth edition of this meeting was hosted by the Department of Cultural Studies of Guanajuato University in a nice environment dedicated to the Arts and Culture. The XIII MWPF was organized by three working groups who organized the corresponding sessions around three topics. The first one was Strings, Cosmology, Astroparticles and Physics Beyond the Standard Model. In this category we included: Cosmic Rays, Gamma Ray Bursts, Physics Beyond the Standard Model (theory and experimental searches), Strings and Cosmology. The working group for this topic was formed by Arnulfo Zepeda, Oscar Loaiza, Axel de la Macorra and Myriam Mondragón. The second topic was Hadronic Matter which included Perturbative QCD, Jets and Diffractive Physics, Hadronic Structure, Soft QCD, Hadron Spectroscopy, Heavy Ion Collisions and Soft Physics at Hadron Colliders, Lattice Results and Instrumentation. The working group for this topic was integrated by Wolfgang Bietenholz and Mariana Kirchbach. The third topic was

Correlation between thyroidal and peripheral blood total T cells, CD8+ T cells, and CD8+ T- regulatory cells and T-cell reactivity to calsequestrin and collagen XIII in patients with Graves' ophthalmopathy.

PubMed

Al-Ansari, Farah; Lahooti, Hooshang; Stokes, Leanne; Edirimanne, Senarath; Wall, Jack

2018-05-22

Purpose/aim of the study: Graves' ophthalmopathy (GO) is closely related to the thyroid autoimmune disorder Graves' disease. Previous studies have suggested roles for thyroidal CD8 +  T cells and autoimmunity against calsequestrin-1 (CASQ)-1 in the link between thyroidal and orbital autoimmune reactions in GO. A role for autoimmunity against CollXIII has also been suggested. In this study, we aimed to investigate correlations between some thyroidal and peripheral blood T-cell subsets and thyroidal T-cell reactivity against CASQ1 and CollXIII in patients with GO. Fresh thyroid tissues were processed by enzyme digestion and density gradient to isolate mononuclear cells (MNCs). Peripheral blood MNCs were also isolated using density gradient. Flow-cytometric analysis was used to identify the various T-cell subsets. T -cell reactivity to CASQ1 and CollXIII was measured by a 5-day culture of the MNCs and BrdU uptake method. We found a positive correlation between thyroidal CD8 +  T cells and CD8 +  T-regulatory (T-reg) cells in patients with GO. Thyroidal T cells from two out of the three patients with GO tested (66.7%) showed a positive response to CASQ1, while thyroidal T cells from none of the six Graves' Disease patients without ophthalmopathy (GD) tested showed a positive response to this antigen. Thyroidal T cells from these patient groups however, showed no significant differences in their response to CollXIII. Our observations provide further evidence for a possible role of thyroidal CD8 +  T cells, CD8 +  T-reg cells and the autoantigen CASQ1 in the link between thyroidal and orbital autoimmune reactions of GO.

Intrinsic thermodynamics of ethoxzolamide inhibitor binding to human carbonic anhydrase XIII

PubMed Central

2012-01-01

Background Human carbonic anhydrases (CAs) play crucial role in various physiological processes including carbon dioxide and hydrocarbon transport, acid homeostasis, biosynthetic reactions, and various pathological processes, especially tumor progression. Therefore, CAs are interesting targets for pharmaceutical research. The structure-activity relationships (SAR) of designed inhibitors require detailed thermodynamic and structural characterization of the binding reaction. Unfortunately, most publications list only the observed thermodynamic parameters that are significantly different from the intrinsic parameters. However, only intrinsic parameters could be used in the rational design and SAR of the novel compounds. Results Intrinsic binding parameters for several inhibitors, including ethoxzolamide, trifluoromethanesulfonamide, and acetazolamide, binding to recombinant human CA XIII isozyme were determined. The parameters were the intrinsic Gibbs free energy, enthalpy, entropy, and the heat capacity. They were determined by titration calorimetry and thermal shift assay in a wide pH and temperature range to dissect all linked protonation reaction contributions. Conclusions Precise determination of the inhibitor binding thermodynamics enabled correct intrinsic affinity and enthalpy ranking of the compounds and provided the means for SAR analysis of other rationally designed CA inhibitors. PMID:22676044

Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII).

PubMed

Bialer, Meir; Johannessen, Svein I; Levy, René H; Perucca, Emilio; Tomson, Torbjörn; White, H Steve

2017-02-01

The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII) took place in Madrid, Spain, on June 26-29, 2016, and was attended by >200 delegates from 31 countries. The present Progress Report provides an update on experimental and clinical results for drugs presented at the Conference. Compounds for which summary data are presented include an AED approved in 2016 (brivaracetam), 12 drugs in phase I-III clinical development (adenosine, allopregnanolone, bumetanide, cannabidiol, cannabidivarin, 2-deoxy-d-glucose, everolimus, fenfluramine, huperzine A, minocycline, SAGE-217, and valnoctamide) and 6 compounds or classes of compounds for which only preclinical data are available (bumetanide derivatives, sec-butylpropylacetamide, FV-082, 1OP-2198, NAX 810-2, and SAGE-689). Overall, the results presented at the Conference show that considerable efforts are ongoing into discovery and development of AEDs with potentially improved therapeutic profiles compared with existing agents. Many of the drugs discussed in this report show innovative mechanisms of action and many have shown promising results in patients with pharmacoresistant epilepsies, including previously neglected rare and severe epilepsy syndromes. Wiley Periodicals, Inc. © 2017 International League Against Epilepsy.

Seven novel mutations in the factor XIII A-subunit gene causing hereditary factor XIII deficiency in 10 unrelated families.

PubMed

Vysokovsky, A; Saxena, R; Landau, M; Zivelin, A; Eskaraev, R; Rosenberg, N; Seligsohn, U; Inbal, A

2004-10-01

Hereditary factor (F)XIII deficiency is a rare bleeding disorder mostly due to mutations in FXIII A subunit. We studied the molecular basis of FXIII deficiency in patients from 10 unrelated families originating from Israel, India and Tunisia. Exons 2-15 of genomic DNA consisting of coding regions and intron/exon boundaries were amplified and sequenced. Structural analysis of the mutations was undertaken by computer modeling. Seven novel mutations were identified in the FXIIIA gene. The propositus from the Ethiopian-Jewish family was found to be a compound heterozygote for two novel mutations: a 10-bp deletion in exon 12 at nucleotides 1652-1661 (followed by 22 altered amino acids and termination codon) and Ala318Val mutation. The propositus of the Tunisian family was homozygous for C insertion after nucleotide 863 within a stretch of six cytosines of exon 7. This insertion results in generation of eight altered amino acids followed by a termination codon downstream. The propositus from Indian-Jewish origin was found to be homozygous for G to T substitution at IVS 11 [+1] resulting in skipping of exons 10 and 11. In addition to the Ala318Val mutation, three of the novel mutations identified are missense mutations: Arg260Leu, Thr398Asn and Gly210Arg each occurring in a homozygous state in an Israeli-Arab and two Indian families, respectively. Structure-function correlation analysis by computer modeling of the new missense mutations predicted that Gly210Arg will cause protein misfolding, Ala318Val and Thr398Asn will interfere with the catalytic process or protein stability, and Arg260Leu will impair dimerization.

Clot retraction is mediated by factor XIII-dependent fibrin-αIIbβ3-myosin axis in platelet sphingomyelin-rich membrane rafts.

PubMed

Kasahara, Kohji; Kaneda, Mizuho; Miki, Toshiaki; Iida, Kazuko; Sekino-Suzuki, Naoko; Kawashima, Ikuo; Suzuki, Hidenori; Shimonaka, Motoyuki; Arai, Morio; Ohno-Iwashita, Yoshiko; Kojima, Soichi; Abe, Mitsuhiro; Kobayashi, Toshihide; Okazaki, Toshiro; Souri, Masayoshi; Ichinose, Akitada; Yamamoto, Naomasa

2013-11-07

Membrane rafts are spatially and functionally heterogenous in the cell membrane. We observed that lysenin-positive sphingomyelin (SM)-rich rafts are identified histochemically in the central region of adhered platelets where fibrin and myosin are colocalized on activation by thrombin. The clot retraction of SM-depleted platelets from SM synthase knockout mouse was delayed significantly, suggesting that platelet SM-rich rafts are involved in clot retraction. We found that fibrin converted by thrombin translocated immediately in platelet detergent-resistant membrane (DRM) rafts but that from Glanzmann's thrombasthenic platelets failed. The fibrinogen γ-chain C-terminal (residues 144-411) fusion protein translocated to platelet DRM rafts on thrombin activation, but its mutant that was replaced by A398A399 at factor XIII crosslinking sites (Q398Q399) was inhibited. Furthermore, fibrin translocation to DRM rafts was impaired in factor XIII A subunit-deficient mouse platelets, which show impaired clot retraction. In the cytoplasm, myosin translocated concomitantly with fibrin translocation into the DRM raft of thrombin-stimulated platelets. Furthermore, the disruption of SM-rich rafts by methyl-β-cyclodextrin impaired myosin activation and clot retraction. Thus, we propose that clot retraction takes place in SM-rich rafts where a fibrin-αIIbβ3-myosin complex is formed as a primary axis to promote platelet contraction.

PST 2009: XIII International Workshop on Polarized Sources Targets and Polarimetry

NASA Astrophysics Data System (ADS)

Lenisa, Paolo

2011-05-01

The workshops on polarized sources, targets, and polarimetry are held every two years. In 2009 the meeting took place in Ferrara, Italy, and was organized by the University of Ferrara and INFN. Sessions on Polarized Proton and Deuterium Sources, Polarized Electron Sources, Polarimetry, Polarized Solid Targets, and Polarized Internal Targets, highlighted topics, recent developments, and progress in the field. A session dedicated to Future Facilities provided an overview of a number of new activities in the spin-physics sector at facilities that are currently in the planning stage. Besides presenting a broad overview of polarized ion sources, electron sources, solid and gaseous targets, and their neighbouring fields, the workshop also addressed the application of polarized atoms in applied sciences and medicine that is becoming increasingly important.

Coated platelets function in platelet-dependent fibrin formation via integrin αIIbβ3 and transglutaminase factor XIII

PubMed Central

Mattheij, Nadine J.A.; Swieringa, Frauke; Mastenbroek, Tom G.; Berny-Lang, Michelle A.; May, Frauke; Baaten, Constance C.F.M.J.; van der Meijden, Paola E.J.; Henskens, Yvonne M.C.; Beckers, Erik A.M.; Suylen, Dennis P.L.; Nolte, Marc W.; Hackeng, Tilman M.; McCarty, Owen J.T.; Heemskerk, Johan W.M.; Cosemans, Judith M.E.M.

2016-01-01

Coated platelets, formed by collagen and thrombin activation, have been characterized in different ways: i) by the formation of a protein coat of α-granular proteins; ii) by exposure of procoagulant phosphatidylserine; or iii) by high fibrinogen binding. Yet, their functional role has remained unclear. Here we used a novel transglutaminase probe, Rhod-A14, to identify a subpopulation of platelets with a cross-linked protein coat, and compared this with other platelet subpopulations using a panel of functional assays. Platelet stimulation with convulxin/thrombin resulted in initial integrin αIIbβ3 activation, the appearance of a platelet population with high fibrinogen binding, (independently of active integrins, but dependent on the presence of thrombin) followed by phosphatidylserine exposure and binding of coagulation factors Va and Xa. A subpopulation of phosphatidylserine-exposing platelets bound Rhod-A14 both in suspension and in thrombi generated on a collagen surface. In suspension, high fibrinogen and Rhod-A14 binding were antagonized by combined inhibition of transglutaminase activity and integrin αIIbβ3. Markedly, in thrombi from mice deficient in transglutaminase factor XIII, platelet-driven fibrin formation and Rhod-A14 binding were abolished by blockage of integrin αIIbβ3. Vice versa, star-like fibrin formation from platelets of a patient with deficiency in αIIbβ3 (Glanzmann thrombasthenia) was abolished upon blockage of transglutaminase activity. We conclude that coated platelets, with initial αIIbβ3 activation and high fibrinogen binding, form a subpopulation of phosphatidylserine-exposing platelets, and function in platelet-dependent star-like fibrin fiber formation via transglutaminase factor XIII and integrin αIIbβ3. PMID:26721892

Compaction of fibrin clots reveals the antifibrinolytic effect of factor XIII.

PubMed

Rijken, D C; Abdul, S; Malfliet, J J M C; Leebeek, F W G; Uitte de Willige, S

2016-07-01

Essentials Factor XIIIa inhibits fibrinolysis by forming fibrin-fibrin and fibrin-inhibitor cross-links. Conflicting studies about magnitude and mechanisms of inhibition have been reported. Factor XIIIa most strongly inhibits lysis of mechanically compacted or retracted plasma clots. Cross-links of α2-antiplasmin to fibrin prevent the inhibitor from being expelled from the clot. Background Although insights into the underlying mechanisms of the effect of factor XIII on fibrinolysis have improved considerably in the last few decades, in particular with the discovery that activated FXIII (FXIIIa) cross-links α2 -antiplasmin to fibrin, the topic remains a matter of debate. Objective To elucidate the mechanisms of the antifibrinolytic effect of FXIII. Methods and Results Platelet-poor plasma clot lysis, induced by the addition of tissue-type plasminogen activator, was measured in the presence or absence of a specific FXIIIa inhibitor. Both in a turbidity assay and in a fluorescence assay, the FXIIIa inhibitor had only a small inhibitory effect: 1.6-fold less tissue-type plasminogen activator was required for 50% clot lysis in the presence of the FXIIIa inhibitor. However, when the plasma clot was compacted by centrifugation, the FXIIIa inhibitor had a strong inhibitory effect, with 7.7-fold less tissue-type plasminogen activator being required for 50% clot lysis in the presence of the FXIIIa inhibitor. In both experiments, the effects of the FXIIIa inhibitor were entirely dependent on the cross-linking of α2 -antiplasmin to fibrin. The FXIIIa inhibitor reduced the amount of α2 -antiplasmin present in the compacted clots from approximately 30% to < 4%. The results were confirmed with experiments in which compaction was achieved by platelet-mediated clot retraction. Conclusions Compaction or retraction of fibrin clots reveals the strong antifibrinolytic effect of FXIII. This is explained by the cross-linking of α2 -antiplasmin to fibrin by FXIIIa, which prevents the

Energy Levels and Radiative Rates for Transitions in F-like Sc XIII and Ne-like Sc XII and Y XXX

NASA Astrophysics Data System (ADS)

Aggarwal, Kanti

2018-05-01

Energy levels, radiative rates and lifetimes are reported for F-like Sc~XIII and Ne-like Sc~XII and Y~XXX for which the general-purpose relativistic atomic structure package ({\\sc grasp}) has been adopted. For all three ions limited data exist in the literature but comparisons have been made wherever possible to assess the accuracy of the calculations. In the present work the lowest 102, 125 and 139 levels have been considered for the respective ions. Additionally, calculations have also been performed with the flexible atomic code ({\\sc fac}) to (particularly) confirm the accuracy of energy levels.

Summary of the XIII International Workshop on Polarized Sources, Targets and Polarimetry

NASA Astrophysics Data System (ADS)

Rathmann, F.

2011-01-01

The workshops on polarized sources, targets, and polarimetry are held every two years. The present meeting took place in Ferrara, Italy, and was organized by the University of Ferrara. Sessions on Polarized Proton and Deuterium Sources, Polarized Electron Sources, Polarimetry, Polarized Solid Targets, and Polarized Internal Targets, highlighted topics, recent developments, and progress in the field. A session decicated to Future Facilities provided an overview of a number of new activities in the spin-physics sector at facilities that are currently in the planning stage. Besides presenting a broad overview of polarized ion sources, electron sources, solid and gaseous targets, and their neighboring fields, the workshop also addressed the application of polarized atoms in applied sciences and medicine that is becoming increasingly important.

Extreme Ultraviolet Emission Lines of Iron Fe XI-XIII

NASA Astrophysics Data System (ADS)

Lepson, Jaan; Beiersdorfer, P.; Brown, G. V.; Liedahl, D. A.; Brickhouse, N. S.; Dupree, A. K.

2013-04-01

The extreme ultraviolet (EUV) spectral region (ca. 20--300 Å) is rich in emission lines from low- to mid-Z ions, particularly from the middle charge states of iron. Many of these emission lines are important diagnostics for astrophysical plasmas, providing information on properties such as elemental abundance, temperature, density, and even magnetic field strength. In recent years, strides have been made to understand the complexity of the atomic levels of the ions that emit the lines that contribute to the richness of the EUV region. Laboratory measurements have been made to verify and benchmark the lines. Here, we present laboratory measurements of Fe XI, Fe XII, and Fe XIII between 40-140 Å. The measurements were made at the Lawrence Livermore electron beam ion trap (EBIT) facility, which has been optimized for laboratory astrophysics, and which allows us to select specific charge states of iron to help line identification. We also present new calculations by the Hebrew University - Lawrence Livermore Atomic Code (HULLAC), which we also utilized for line identification. We found that HULLAC does a creditable job of reproducing the forest of lines we observed in the EBIT spectra, although line positions are in need of adjustment, and line intensities often differed from those observed. We identify or confirm a number of new lines for these charge states. This work was supported by the NASA Solar and Heliospheric Program under Contract NNH10AN31I and the DOE General Plasma Science program. Work was performed in part under the auspices of the Department of Energy by Lawrence Livermore National Laboratory under Contract DEAC52-07NA27344.

Recombinant Factor XIII Mitigates Hemorrhagic Shock-Induced Organ Dysfunction

PubMed Central

Zaets, Sergey B.; Xu, Da-Zhong; Lu, Qi; Feketova, Eleonora; Berezina, Tamara L.; Malinina, Inga V.; Deitch, Edwin A.; Olsen, Eva H.

2012-01-01

Background Plasma factor XIII (FXIII) is responsible for stabilization of fibrin clot at the final stage of blood coagulation. Since FXIII has also been shown to modulate inflammation, endothelial permeability, as well as diminish multiple organ dysfunction (MOD) after gut ischemia-reperfusion injury, we hypothesized that FXIII would reduce MOD caused by trauma-hemorrhagic shock (THS). Materials and methods Rats were subjected to a 90 min THS or trauma sham shock (TSS) and treated with either recombinant human FXIII A2 subunit (rFXIII) or placebo immediately after resuscitation with shed blood or at the end of the TSS period. Lung permeability, lung and gut myeloperoxidase (MPO) activity, gut histology, neutrophil respiratory burst, microvascular blood flow in the liver and muscles, and cytokine levels were measured 3 h after the THS or TSS. FXIII levels were measured before THS or TSS and after the 3-h post-shock period. Results THS-induced lung permeability as well as lung and gut MPO activity was significantly lower in rFXIII-treated than in placebo-treated animals. Similarly, rFXIII-treated rats had lower neutrophil respiratory burst activity and less ileal mucosal injury. rFXIII-treated rats also had a higher liver microvascular blood flow compared with the placebo group. Cytokine response was more favorable in rFXIII-treated animals. Trauma-hemorrhagic shock did not cause a drop in FXIII activity during the study period. Conclusions Administration of rFXIII diminishes THS-induced MOD in rats, presumably by preservation of the gut barrier function, limitation of polymorphonuclear leukocyte (PMN) activation, and modulation of the cytokine response. PMID:21276979

Functional factor XIII-A is exposed on the stimulated platelet surface

PubMed Central

Mitchell, Joanne L.; Lionikiene, Ausra S.; Fraser, Steven R.; Whyte, Claire S.; Booth, Nuala A.

2014-01-01

Factor XIII (FXIII) stabilizes thrombi against fibrinolysis by cross-linking α2-antiplasmin (α2AP) to fibrin. Cellular FXIII (FXIII-A) is abundant in platelets, but the extracellular functions of this pool are unclear because it is not released by classical secretion mechanisms. We examined the function of platelet FXIII-A using Chandler model thrombi formed from FXIII-depleted plasma. Platelets stabilized FXIII-depleted thrombi in a transglutaminase-dependent manner. FXIII-A activity on activated platelets was unstable and was rapidly lost over 1 hour. Inhibiting platelet activation abrogated the ability of platelets to stabilize thrombi. Incorporating a neutralizing antibody to α2AP into FXIII-depleted thrombi revealed that the stabilizing effect of platelet FXIII-A on lysis was α2AP dependent. Platelet FXIII-A activity and antigen were associated with the cytoplasm and membrane fraction of unstimulated platelets, and these fractions were functional in stabilizing FXIII-depleted thrombi against lysis. Fluorescence confocal microscopy and flow cytometry revealed exposure of FXIII-A on activated membranes, with maximal signal detected with thrombin and collagen stimulation. FXIII-A was evident in protruding caps on the surface of phosphatidylserine-positive platelets. Our data show a functional role for platelet FXIII-A through exposure on the activated platelet membrane where it exerts antifibrinolytic function by cross-linking α2AP to fibrin. PMID:25331118

[A case of pancreatic and duodenal fistula after total gastrectomy successfully treated with coagulation factor XIII].

PubMed

Nishino, Hitoe; Kojima, Kazuhiro; Oshima, Hirokazu; Nakagawa, Koji; Fumura, Masao; Kikuchi, Norio

2013-11-01

Pancreatic fistula( PF) is a challenging postoperative complication. We report a case of PF following gastrectomy successfully treated using intravenous coagulation factor XIII( FXIII).A 78-year-old man with early gastric cancer underwent total gastrectomy with Roux-en-Y reconstruction. PF developed postoperatively, following which, leakage from the duodenal stump was observed. Percutaneous drainage and re-operative surgery were performed. A somatostatin analogue, antibiotic drugs, and gabexate mesilate were administrated along with nutritional support. The pancreatic and duodenal fistula had been producing duodenal juice for over 30 days since the re-operative surgery. As suspected, reduced FXIII activity was confirmed in the patient. After administering FXIII for 5 days, the amount of duodenal juice from the fistula markedly reduced, and the fistula closed immediately afterwards. The results of our study suggest that administration of FXIII could be a reasonable and effective treatment for patients with pancreatic or/and enterocutaneous fistula who are resistant to standard treatments.

Factor XIII deficiency in Iran: a comprehensive review of the literature.

PubMed

Dorgalaleh, Akbar; Naderi, Majid; Hosseini, Maryam Sadat; Alizadeh, Shaban; Hosseini, Soudabeh; Tabibian, Shadi; Eshghi, Peyman

2015-04-01

Factor XIII deficiency (FXIIID) is a rare bleeding disorder with an estimated prevalence of 1 in 2-million population worldwide. In Iran, a Middle Eastern country with a high rate of consanguineous marriages, there are approximately 473 patients afflicted with FXIIID. An approximately 12-fold higher prevalence of FXIIID is estimated in Iran in comparison with overall worldwide frequency. In this study, we have undertaken a comprehensive review on different aspects of FXIIID in the Iranian population. The distribution of this disease in different regions of Iran reveals that Sistan and Baluchestan Province has not only the highest number of patients with FXIIID in Iran but the highest global incidence of this condition. Among Iranian patients, umbilical cord bleeding, hematoma, and prolonged wound bleeding are the most frequent clinical manifestations. There are several disease causing mutations in Iranian patients with FXIIID, with Trp187Arg being the most common mutation in FXIIID in Iran. Traditionally, the management of FXIIID in Iran was only based on administration of fresh frozen plasma or cryoprecipitate, until 2009 when FXIII concentrate became available for patient management. Various studies have evaluated the efficacy and safety of prophylactic regimens in different situations with valuable findings. Although the focus of this study is on Iran, it offers considerable insight into FXIIID, which can be applied more extensively to improve the management and quality of life in all affected patients. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

In-situ AFM measurement of single fibrin fiber stiffness before and after addition of Factor XIII

NASA Astrophysics Data System (ADS)

Houser, John; O'Brien, E. Timothy; Lord, Susan T.; Superfine, Richard; Falvo, Michael R.

2008-10-01

Fibrin fibers are the main structural component of blood clots. Ligation of fibrin by native Factor XIII (FXIII) serves to fine tune the mechanical properties of the clot. Mechanical alteration is important because a clot must be stiff enough to resist forces from blood flow but compliant enough to prevent embolism (fracture). Cone and Plate measurements of fibrin gels, which represent the vast majority of mechanical measurements on fibrin, show that FXIII increases clot stiffness. More recently, measurements on individual fibrin fibers show that they exhibit remarkable extensibility, breaking at strains up to 300%. As of yet, the origin of this extensibility is not fully understood. The different responses of ligated and unligated fibrin fibers can give us clues as to it's mechanism of extension. We use a combined fluorescence/atomic force microscope to stretch individual, isolated, fibrin fibers and then compare force extension curves of the same fiber before and after addition of FXIII. We found up to a 3.5-fold increase in fiber stiffness after addition of FXIII. We also show stiffening of individual fibrin fibers after crosslinking by gluteraldehyde.

The Non-catalytic B Subunit of Coagulation Factor XIII Accelerates Fibrin Cross-linking*

PubMed Central

Souri, Masayoshi; Osaki, Tsukasa; Ichinose, Akitada

2015-01-01

Covalent cross-linking of fibrin chains is required for stable blood clot formation, which is catalyzed by coagulation factor XIII (FXIII), a proenzyme of plasma transglutaminase consisting of catalytic A (FXIII-A) and non-catalytic B subunits (FXIII-B). Herein, we demonstrate that FXIII-B accelerates fibrin cross-linking. Depletion of FXIII-B from normal plasma supplemented with a physiological level of recombinant FXIII-A resulted in delayed fibrin cross-linking, reduced incorporation of FXIII-A into fibrin clots, and impaired activation peptide cleavage by thrombin; the addition of recombinant FXIII-B restored normal fibrin cross-linking, FXIII-A incorporation into fibrin clots, and activation peptide cleavage by thrombin. Immunoprecipitation with an anti-fibrinogen antibody revealed an interaction between the FXIII heterotetramer and fibrinogen mediated by FXIII-B and not FXIII-A. FXIII-B probably binds the γ-chain of fibrinogen with its D-domain, which is near the fibrin polymerization pockets, and dissociates from fibrin during or after cross-linking between γ-chains. Thus, FXIII-B plays important roles in the formation of a ternary complex between proenzyme FXIII, prosubstrate fibrinogen, and activator thrombin. Accordingly, congenital or acquired FXIII-B deficiency may result in increased bleeding tendency through impaired fibrin stabilization due to decreased FXIII-A activation by thrombin and secondary FXIII-A deficiency arising from enhanced circulatory clearance. PMID:25809477

The Archive of the Amateur Observation Network of the International Halley Watch. Volume 2; Comet Halley

NASA Technical Reports Server (NTRS)

Edberg, Stephen J. (Editor)

1996-01-01

The International Halley Watch (IHW) was organized for the purpose of gathering and archiving the most complete record of the apparition of a comet, Halley's Comet (1982i = 1986 III = 1P/Halley), ever compiled. The redirection of the International Sun-Earth Explorer 3 (ISEE-3) spacecraft, subsequently renamed the International Cometary Explorer (ICE), toward Comet Giacobini- Zinner (1984e = 1985 XIII = 21P/Giacobini-Zinner) prompted the initiation of a formal watch on that comet. All the data collected on P/Giacobini-Zinner and P/Halley have been published on CD-ROM in the Comet Halley Archive. This document contains a printed version of the archive data, collected by amateur astronomers, on these two comets. Volume 1 contains the Comet Giacobini-Zinner data archive and Volume 2 contains the Comet Halley archive. Both volumes include information on how to read the data in both archives, as well as a history of both comet watches (including the organizing of the network of astronomers and lessons learned from that experience).

Revisiting the mechanism of coagulation factor XIII activation and regulation from a structure/functional perspective

PubMed Central

Gupta, Sneha; Biswas, Arijit; Akhter, Mohammad Suhail; Krettler, Christoph; Reinhart, Christoph; Dodt, Johannes; Reuter, Andreas; Philippou, Helen; Ivaskevicius, Vytautas; Oldenburg, Johannes

2016-01-01

The activation and regulation of coagulation Factor XIII (FXIII) protein has been the subject of active research for the past three decades. Although discrete evidence exists on various aspects of FXIII activation and regulation a combinatorial structure/functional view in this regard is lacking. In this study, we present results of a structure/function study of the functional chain of events for FXIII. Our study shows how subtle chronological submolecular changes within calcium binding sites can bring about the detailed transformation of the zymogenic FXIII to its activated form especially in the context of FXIIIA and FXIIIB subunit interactions. We demonstrate what aspects of FXIII are important for the stabilization (first calcium binding site) of its zymogenic form and the possible modes of deactivation (thrombin mediated secondary cleavage) of the activated form. Our study for the first time provides a structural outlook of the FXIIIA2B2 heterotetramer assembly, its association and dissociation. The FXIIIB subunits regulatory role in the overall process has also been elaborated upon. In summary, this study provides detailed structural insight into the mechanisms of FXIII activation and regulation that can be used as a template for the development of future highly specific therapeutic inhibitors targeting FXIII in pathological conditions like thrombosis. PMID:27453290

The Archive of the Amateur Observation Network of the International Halley Watch. Volume 1; Comet Giacobini-Zinner

NASA Technical Reports Server (NTRS)

Edberg, Stephen J. (Editor)

1966-01-01

The International Halley Watch (IHW) was organized for the purpose of gathering and archiving the most complete record of the apparition of a comet, Halley's Comet (1982i = 1986 III = 1P/Halley), ever compiled. The redirection of the International Sun-Earth Explorer 3 (ISEE-3) spacecraft, subsequently renamed the International Cometary Explorer (ICE), toward Comet Giacobini-Zinner (1984e = 1985 XIII = 21P/Giacobini-Zinner) prompted the initiation of a formal watch on that comet. All the data collected on P/Giacobini-Zinner and P/Halley have been published on CD-ROM in the Comet Halley Archive. This document contains a printed version of the archive data, collected by amateur astronomers, on these two comets. Volume 1 contains the Comet Giacobini-Zinner data archive and Volume 2 contains the Comet Halley archive. Both volumes include information on how to read the data in both archives, as well as a history of both comet watches (including the organizing of the network of astronomers and lessons learned from that experience).

The Archive of the Amateur Observation Network of the International Halley Watch. Volume 1; Comet Giacobini-Zinner

NASA Technical Reports Server (NTRS)

Edberg, Stephen J. (Editor)

1996-01-01

The International Halley Watch (IHW) was organized for the purpose of gathering and archiving the most complete record of the apparition of a comet, Comet Halley (1982i = 1986 III = 1P/Halley), ever compiled. The redirection of the International Cometary Explorer (ICE), toward Comet Giacobini-Zinner (1984e = 1985 XIII = 21P/Giacobini-Zinner) prompted the initiation of a formal watch on that comet. All the data collected on P/Giacobini-Zinner and P/Halley have been published on CD-ROM in the Comet Halley Archive. This document contains a printed version of the archive data, collected by amateur astronomers, on these two comets. Volume 1 contains the Comet Giacobini-Zinner data archive and Volume 2 contains the Comet Halley archive. Both volumes include information on how to read the data in both archives, as well as a history of both comet watches (including the organizing of the network of astronomers and lessons learned from that experience).

Evaluating Factor XIII Specificity for Glutamine-Containing Substrates Using a MALDI-TOF Mass Spectrometry Assay

PubMed Central

Doiphode, Prakash G.; Malovichko, Marina V.; Mouapi, Kelly Njine; Maurer, Muriel C.

2014-01-01

Activated Factor XIII (FXIIIa) catalyzes the formation of γ-glutamyl-ε-lysyl cross-links within the fibrin blood clot network. Although several cross-linking targets have been identified, the characteristic features that define FXIIIa substrate specificity are not well understood. To learn more about how FXIIIa selects its targets, a matrix-assisted laser desorption ionization – time of flight mass spectrometry (MALDI-TOF MS) based assay was developed that could directly follow the consumption of a glutamine-containing substrate and the formation of a cross-linked product with glycine ethylester. This FXIIIa kinetics assay is no longer reliant on a secondary coupled reaction, on substrate labeling, or on detecting the final deacylation portion of the transglutaminase reaction. With the MALDI-TOF MS assay, glutamine-containing peptides derived from α2-antiplasmin, S. Aureus fibronectin binding protein A, and thrombin activatable fibrinolysis inhibitor were examined directly. Results suggest that the FXIIIa active site surface responds to changes in substrate residues following the reactive glutamine. The P-1 substrate position is sensitive to charge character and the P-2 and P-3 to the broad FXIIIa substrate specificity pockets. The more distant P-8 to P-11 region serves as a secondary substrate anchoring point. New knowledge on FXIIIa specificity may be used to design better substrates or inhibitors of this transglutaminase. PMID:24751466

PREFACE: XIII International Workshop on Neutrino Factories, Super beams and Beta beams (NUFACT11)

NASA Astrophysics Data System (ADS)

Blondel, Alain; Efthymiopoulos, Ilias; Prior, Gersende

2013-02-01

These proceedings present the written contributions from participants of the International Workshop on Neutrino Factories, Superbeams and Betabeams (NuFact11), which was held in Geneva, Switzerland, on 1-6 August 2011. This was the 13th of the series of NuFact annual meetings, which started in 1999. The six-day scientific programme of NuFact11 consisted of 42 plenary and 111 parallel talks and various poster sessions, with the participation of 191 researchers from 19 countries. In addition the International Neutrino Summer School 2011 was held in the two weeks preceding the workshop. It was intended for young scientists starting their research in neutrino physics in such a way that they would be able to participate and contribute to the workshop. The objective of the NuFact workshops is to build up, time after time, the scientific knowledge on accelerator facilities aimed at the study of neutrino oscillation. The organization of the workshop is tailored to ensure continuity and growth of knowledge: working group conveners have a mandate of three consecutive meetings and maintain an updated list of questions. In order to emphasize further the 'work' (by opposition to 'shop') part of the meeting, we organized a 'round table discussion' at the beginning of the workshop, in which the invitees were asked not only to provide their answers to a preset list of questions, but to propose their own questions to the participants. This was quite successful and we have compiled the answers in this book. Topics addressed at NuFact included neutrino oscillation physics, neutrino cross-sections and detectors, accelerator physics, muon physics and high-intensity applications of muons beams. This variety of subjects is reflected in these proceedings. The editors hope to provide more than enjoyable and fruitful reading for those interested in neutrino physics, a stepping stone along the path to always more insightful research on these mysterious neutrinos, which certainly contain the

Bridging Cultures and Traditions for Educational and International Development: Comparative Research, Dialogue and Difference

NASA Astrophysics Data System (ADS)

Crossley, Michael

2008-07-01

Addressing the central theme of the XIII World Congress, the paper explores a number of contemporary theoretical, methodological and organisational developments in the field of comparative education. In doing so it draws upon the author's recent work and a selection of studies carried out in the South Pacific, the Caribbean and Africa. It is argued that disciplined comparative and international research can contribute much to the development of theory and methodology - as well as to the improvement of policy and practice in education world-wide. For this to be realised it is maintained that ongoing efforts to challenge and `reconceptualise' the field deserve sustained support - and increased attention to a more effective `bridging of cultures and traditions'. This `bridging' thesis is examined in greater depth, pointing to possible ways forward for those engaged in advancing the future of comparative research in education and in the social sciences more generally.

Energy levels, lifetimes, and transition rates for the selenium isoelectronic sequence Pd XIII-Te XIX, Xe XXI-Nd XXVII, W XLI

NASA Astrophysics Data System (ADS)

Wang, K.; Yang, X.; Chen, Z. B.; Si, R.; Chen, C. Y.; Yan, J.; Zhao, X. H.; Dang, W.

2017-09-01

Energy levels, wavelengths, lifetimes, oscillator strengths, and electric dipole (E1), magnetic dipole (M1), electric quadrupole (E2), magnetic quadrupole (M2) transition rates among the 46 fine structure levels belonging to the ([ Ar ] 3d10) 4s2 4p4, ([ Ar ] 3d10) 4s2 4p3 4 d, and ([ Ar ] 3d10) 4 s 4p5 configurations for the selenium isoelectronic sequence Pd XIII-Te XIX, Xe XXI-Nd XXVII, W XLI are reported. These data are determined in the multi-configuration Dirac-Fock (MCDF) approach, in which relativistic effects, main electron correlations within the n = 7 complex, Breit interaction (BI), and quantum electrodynamic (QED) corrections are included. The many-body perturbation theory (MBPT) method is also employed as an independent calculation to confirm the present accuracy, taking W XLI as an example. Comparisons and analysis are made between the present results and available experimental and theoretical ones, and good agreements are obtained. These accurate data are expected to be useful in nuclear fusion research and astrophysical applications.

Safety of recombinant human factor XIII in a cynomolgus monkey model of extracorporeal blood circulation.

PubMed

Ponce, R; Armstrong, K; Andrews, K; Hensler, J; Waggie, K; Heffernan, J; Reynolds, T; Rogge, M

2005-01-01

Factor XIII (FXIII) is a thrombin-activated plasma coagulation factor critical for blood clot stabilization and longevity. Administration of exogenous FXIII to replenish depleted stores after major surgery, including cardiopulmonary bypass, may reduce bleeding complications and transfusion requirements. Thus, a model of extracorporeal circulation (ECC) was developed in adult male cynomolgus monkeys (Macaca fascicularis) to evaluate the nonclinical safety of recombinant human FXIII (rFXIII). The hematological and coagulation profile in study animals during and after 2 h of ECC was similar to that reported for humans during and after cardiopulmonary bypass, including observations of anemia, thrombocytopenia, and activation of coagulation and platelets. Intravenous slow bolus injection of 300 U/kg (2.1 mg/kg) or 1000 U/kg (7 mg/kg) rFXIII after 2 h of ECC was well tolerated in study animals, and was associated with a dose-dependent increase in FXIII activity. No clinically significant effects in respiration, ECG, heart rate, blood pressure, body temperature, clinical chemistry, hematology (including platelet counts), or indicators of thrombosis (thrombin:anti-thrombin complex and D-Dimer) or platelet activation (platelet factor 4 and beta-thromboglobulin) were related to rFXIII administration. Specific examination of brain, heart, lung, liver, and kidney from rFXIII-treated animals provided no evidence of histopathological alterations suggestive of subclinical hemorrhage or thrombosis. Taken as a whole, the results demonstrate the ECC model suitably replicated the clinical presentation reported for humans during and after cardiopulmonary bypass surgery, and do not suggest significant concerns regarding use of rFXIII in replacement therapy after extracorporeal circulation.

RECOMBINANT FACTOR XIII DIMINISHES MULTIPLE ORGAN DYSFUNCTION IN RATS CAUSED BY GUT ISCHEMIA-REPERFUSION INJURY

PubMed Central

Zaets, Sergey B.; Xu, Da-Zhong; Lu, Qi; Feketova, Eleonora; Berezina, Tamara L.; Gruda, Maryann; Malinina, Inga V.; Deitch, Edwin A.; Olsen, Eva H. N.

2010-01-01

Plasma factor XIII (FXIII) is responsible for stabilization of fibrin clot at the final stage of blood coagulation. Because FXIII has also been shown to modulate inflammation and endothelial permeability, we hypothesized that FXIII diminishes multiple organ dysfunction caused by gut I/R injury. A model of superior mesenteric artery occlusion (SMAO) was used to induce gut I/R injury. Rats were subjected to 45-min SMAO or sham SMAO and treated with recombinant human FXIII A2 subunit (rFXIII) or placebo at the beginning of the reperfusion period. Lung permeability, lung and gut myeloperoxidase activity, gut histology, neutrophil respiratory burst, and microvascular blood flow in the liver and muscles were measured after a 3-h reperfusion period. The effect of activated rFXIII on transendothelial resistance of human umbilical vein endothelial cells was tested in vitro. Superior mesenteric artery occlusion–induced lung permeability as well as lung and gut myeloperoxidase activity was significantly lower in rFXIII-treated versus untreated animals. Similarly, rFXIII-treated rats had lower neutrophil respiratory burst activity and ileal mucosal injury. Rats treated with rFXIII also had higher liver microvascular blood flow compared with the placebo group. Superior mesenteric artery occlusion did not cause FXIII consumption during the study period. In vitro, activated rFXIII caused a dose-dependent increase in human umbilical vein endothelial cell monolayer resistance to thrombin-induced injury. Thus, administration of rFXIII diminishes SMAO-induced multiple organ dysfunction in rats, presumably by preservation of endothelial barrier function and the limitation of polymorphonuclear leukocyte activation. PMID:18948851

38 CFR 17.81 - Contracts for residential treatment services for veterans with alcohol or drug dependence or...

Code of Federal Regulations, 2014 CFR

2014-07-01

... contract. (6) Demonstrate an existing capability to furnish the following: (i) A supervised alcohol and... social service. (x) Individual counseling as appropriate. (xi) Opportunities for learning/development of...-free life style). (xiii) Opportunities for learning, testing, and internalizing knowledge of illness...

38 CFR 17.81 - Contracts for residential treatment services for veterans with alcohol or drug dependence or...

Code of Federal Regulations, 2013 CFR

2013-07-01

... contract. (6) Demonstrate an existing capability to furnish the following: (i) A supervised alcohol and... social service. (x) Individual counseling as appropriate. (xi) Opportunities for learning/development of...-free life style). (xiii) Opportunities for learning, testing, and internalizing knowledge of illness...

Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke.

PubMed

Hanscombe, Ken B; Traylor, Matthew; Hysi, Pirro G; Bevan, Stephen; Dichgans, Martin; Rothwell, Peter M; Worrall, Bradford B; Seshadri, Sudha; Sudlow, Cathie; Williams, Frances M K; Markus, Hugh S; Lewis, Cathryn M

2015-08-01

Abnormal coagulation has been implicated in the pathogenesis of ischemic stroke, but how this association is mediated and whether it differs between ischemic stroke subtypes is unknown. We determined the shared genetic risk between 14 coagulation factors and ischemic stroke and its subtypes. Using genome-wide association study results for 14 coagulation factors from the population-based TwinsUK sample (N≈2000 for each factor), meta-analysis results from the METASTROKE consortium ischemic stroke genome-wide association study (12 389 cases, 62 004 controls), and genotype data for 9520 individuals from the WTCCC2 ischemic stroke study (3548 cases, 5972 controls-the largest METASTROKE subsample), we explored shared genetic risk for coagulation and stroke. We performed three analyses: (1) a test for excess concordance (or discordance) in single nucleotide polymorphism effect direction across coagulation and stroke, (2) an estimation of the joint effect of multiple coagulation-associated single nucleotide polymorphisms in stroke, and (3) an evaluation of common genetic risk between coagulation and stroke. One coagulation factor, factor XIII subunit B (FXIIIB), showed consistent effects in the concordance analysis, the estimation of polygenic risk, and the validation with genotype data, with associations specific to the cardioembolic stroke subtype. Effect directions for FXIIIB-associated single nucleotide polymorphisms were significantly discordant with cardioembolic disease (smallest P=5.7×10(-04)); the joint effect of FXIIIB-associated single nucleotide polymorphisms was significantly predictive of ischemic stroke (smallest P=1.8×10(-04)) and the cardioembolic subtype (smallest P=1.7×10(-04)). We found substantial negative genetic covariation between FXIIIB and ischemic stroke (rG=-0.71, P=0.01) and the cardioembolic subtype (rG=-0.80, P=0.03). Genetic markers associated with low FXIIIB levels increase risk of ischemic stroke cardioembolic subtype. © 2015 The

Bridging Cultures and Traditions for Educational and International Development: Comparative Research, Dialogue and Difference

ERIC Educational Resources Information Center

Crossley, Michael

2008-01-01

Addressing the central theme of the XIII World Congress, the paper explores a number of contemporary theoretical, methodological and organisational developments in the field of comparative education. In doing so it draws upon the author's recent work and a selection of studies carried out in the South Pacific, the Caribbean and Africa. It is…

78 FR 70352 - Notice of Government in the Sunshine Regular Board of Directors Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-25

... NEIGHBORHOOD REINVESTMENT CORPORATION Notice of Government in the Sunshine Regular Board of.... Approval of Minutes III. Management Internal Operations Review IV. Non-Network Grant Policy V. MHA... Board XIII. Adjournment Jeffrey T. Bryson, General Counsel/Secretary. [FR Doc. 2013-28325 Filed 11-21-13...

Understanding the Dynamic System of Terrorist-Government Interaction

DTIC Science & Technology

2003-03-01

organizations out of support or for services rendered (Department of State, 2002:65; Wallace, 2003:2). However, financial support does not have to be in...America’s critical infrastructure encompasses a large number of sectors[:]” agriculture, food, water, public health, emergency services , government...military, international law enforcement community, or the U.S. or international intelligence services (Department of State, 2002:vii-xiii). In fact

Bangladesh v. India: A Positive Step Forward in Public Order of the Seas

DTIC Science & Technology

2017-09-05

between India and Bangladesh, “regarding the delimitation of the maritime boundary between them in the territorial sea, the exclusive economic zone...Diplomatic Relations ................................................................................................... 31 Political and Economic ...xiii Glossary CLCS Commission on the Limits of the Continental Shelf EEZ Exclusive Economic Zone ICJ International Court of

Beyond Consolidation: U.S. Government International Broadcasting in the Post-Cold War Era

DTIC Science & Technology

1994-01-01

vii A c kowledgments .......................................... xiii 1. INTRODUCTION ....................................... 1 2. THE UNITED STATES IN...military power more generally, is diminishing in relevance, paced by the decline of U.S. economic preponderance. The difference between military and...economic power on the one hand, and political and moral authority on the other hand, has been made starkly clear at the beginning of the post-Cold War era

A novel Sarcocystis neurona genotype XIII is associated with severe encephalitis in an unexpectedly broad range of marine mammals from the northeastern Pacific Ocean.

PubMed

Barbosa, Lorraine; Johnson, Christine K; Lambourn, Dyanna M; Gibson, Amanda K; Haman, Katherine H; Huggins, Jessica L; Sweeny, Amy R; Sundar, Natarajan; Raverty, Stephen A; Grigg, Michael E

2015-08-01

Sarcocystis neurona is an important cause of protozoal encephalitis among marine mammals in the northeastern Pacific Ocean. To characterise the genetic type of S. neurona in this region, samples from 227 stranded marine mammals, most with clinical or pathological evidence of protozoal disease, were tested for the presence of coccidian parasites using a nested PCR assay. The frequency of S. neurona infection was 60% (136/227) among pinnipeds and cetaceans, including seven marine mammal species not previously known to be susceptible to infection by this parasite. Eight S. neurona fetal infections identified this coccidian parasite as capable of being transmitted transplacentally. Thirty-seven S. neurona-positive samples were multilocus sequence genotyped using three genetic markers: SnSAG1-5-6, SnSAG3 and SnSAG4. A novel genotype, referred to as Type XIII within the S. neurona population genetic structure, has emerged recently in the northeastern Pacific Ocean and is significantly associated with an increased severity of protozoal encephalitis and mortality among multiple stranded marine mammal species. Published by Elsevier Ltd.

A novel Sarcocystis neurona genotype XIII is associated with severe encephalitis in an unexpectedly broad range of marine mammals from the northeastern Pacific Ocean

PubMed Central

Barbosa, Lorraine; Johnson, Christine K.; Lambourn, Dyanna M.; Gibson, Amanda K.; Haman, Katherine H.; Huggins, Jessica L.; Sweeny, Amy R.; Sundar, Natarajan; Raverty, Stephen A.; Grigg, Michael E.

2015-01-01

Sarcocystis neurona is an important cause of protozoal encephalitis among marine mammals in the northeastern Pacific Ocean. To characterize the genetic type of S. neurona in this region, samples from 227 stranded marine mammals, most with clinical or pathological evidence of protozoal disease, were tested for the presence of coccidian parasites using a nested PCR assay. The frequency of S. neurona infection was 60% (136/227) among pinnipeds and cetaceans, including seven marine mammal species not previously known to be susceptible to infection by this parasite. Eight S. neurona fetal infections identified this coccidian parasite as capable of being transmitted transplacentally. Thirty-seven S. neurona-positive samples were multilocus sequence genotyped using three genetic markers: SnSAG1-5-6, SnSAG3 and SnSAG4. A novel genotype, referred to as Type XIII within the S. neurona population genetic structure, has emerged recently in the northeastern Pacific Ocean and is significantly associated with an increased severity of protozoal encephalitis and mortality among multiple stranded marine mammal species. PMID:25997588

Special Operations Liaison Officer: Looking Back to See the Future

DTIC Science & Technology

2014-06-01

Officer GSN global SOF network HQ Headquarters HRC Human Resources Command HRM human resource management xiii IEP International...life away from a U.S. base in a foreign country In May 2013, the USSOCOM International Engagement Program ( IEP ) provided funding to the Naval...manages the USSOCOM IEP . The intent of this study was to produce a formal career path for SOLOs that would eliminate most, if not all, the current

Factor XIII Val34Leu polymorphism and the risk of myocardial infarction under the age of 36 years.

PubMed

Rallidis, Loukianos S; Politou, Marianna; Komporozos, Christoforos; Panagiotakos, Demosthenes B; Belessi, Chrisoula I; Travlou, Anthi; Lekakis, John; Kremastinos, Dimitrios T

2008-06-01

There are limited and controversial data regarding the impact of factor XIII (FXIII) Val34Leu polymorphism in the pathogenesis of premature myocardial infarction (MI). We examined whether FXIII Val34Leu polymorphism is associated with the development of early MI. We recruited 159 consecutive patients who had survived their first acute MI under the age of 36 years (mean age = 32.1 +/- 3.6 years, 138 were men). The control group consisted of 121 healthy individuals matched with cases for age and sex, without a family history of premature coronary heart disease (CHD). FXIII Val34Leu polymorphism was tested with polymerase chain reaction and reverse hybridization. There was a lower prevalence of carriers of the Leu34 allele in patients than in controls (30.2 vs. 47.1%, p = 0.006). FXIII Val34Leu polymorphism was associated with lower risk for acute MI after adjusting for major cardiovascular risk factors (odds ratio [OR] = 0.51, 95% confidence interval [CI] 0.27-0.95, p = 0.03). Subgroup analysis according to angiographic findings ("normal" coronary arteries [n = 29] or significant CHD [n = 130]) showed that only patients with MI and significant CHD had lower prevalence of carriers of the Leu34 allele compared to controls after adjusting for major cardiovascular risk factors (OR = 0.42, 95% CI 0.22-0.83, p = 0.01). Our data indicate that FXIII Val34Leu polymorphism has a protective effect against the development of MI under the age of 36 years, particularly in the setting of significant CHD.

Photogrammetric camera calibration

USGS Publications Warehouse

Tayman, W.P.; Ziemann, H.

1984-01-01

Section 2 (Calibration) of the document "Recommended Procedures for Calibrating Photogrammetric Cameras and Related Optical Tests" from the International Archives of Photogrammetry, Vol. XIII, Part 4, is reviewed in the light of recent practical work, and suggestions for changes are made. These suggestions are intended as a basis for a further discussion. ?? 1984.

Chemical and Photographic Evaluation of Rigid Explosive Transfer Lines.

DTIC Science & Technology

1984-05-01

and Kaplan , L. A., J. Org. Chem., Vol. 31, 1966, p. 857. 4. Dacons, J. C., Adolph, H. G., and Kpmlet, M. J., Heat Resistant Explosives, XIII...Sand Canyon Road % Saugus, CA 91351 Jet Propulsion Laboratory Attn: W. Gin 125-124 1 Rockwell International 4800 Oak Grove Drive Attn: L. Corvin ( MA2

Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: hemostatic abnormalities in mutant mice and characterization of the coagulation deficit.

PubMed

Lauer, Peter; Metzner, Hubert J; Zettlmeissl, Gerd; Li, Meng; Smith, Austin G; Lathe, Richard; Dickneite, Gerhard

2002-12-01

Blood coagulation factor XIII (FXIII) promotes cross-linking of fibrin during blood coagulation; impaired clot stabilization in human genetic deficiency is associated with marked pathologies of major clinical impact, including bleeding symptoms and deficient wound healing. To investigate the role of FXIII we employed homologous recombination to generate a targeted deletion of the inferred exon 7 of the FXIII-A gene. FXIII transglutaminase activity in plasma was reduced to about 50% in mice heterozygous for the mutant allele, and was abolished in homozygous null mice. Plasma fibrin gamma-dimerization was also indetectable in the homozygous deficient animals, confirming the absence of activatable FXIII. Homozygous mutant mice were fertile, although reproduction was impaired. Bleeding episodes, hematothorax, hematoperitoneum and subcutaneous hemorrhage in mutant mice were associated with reduced survival. Arrest of tail-tip bleeding in FXIII-A deficient mice was markedly and significantly delayed; replacement of mutant mice with human plasma FXIII (Fibrogammin P) restored bleeding time to within the normal range. Thrombelastography (TEG) experiments demonstrated impaired clot stabilization in FXIII-A mutant mice, replacement with human FXIII led to dose-dependent TEG normalization. The mutant mice thus reiterate some key features of the human genetic disorder: they will be valuable in assessing the role of FXIII in other associated pathologies and the development of new therapies.

Local activation of coagulation factor XIII reduces systemic complications and improves the survival of mice after Streptococcus pyogenes M1 skin infection.

PubMed

Deicke, Christin; Chakrakodi, Bhavya; Pils, Marina C; Dickneite, Gerhard; Johansson, Linda; Medina, Eva; Loof, Torsten G

2016-11-01

Coagulation is a mechanism for wound healing after injury. Several recent studies delineate an additional role of the intrinsic pathway of coagulation, also known as the contact system, in the early innate immune response against bacterial infections. In this study, we investigated the role of factor XIII (FXIII), which is activated upon coagulation induction, during Streptococcus pyogenes-mediated skin and soft tissue infections. FXIII has previously been shown to be responsible for the immobilization of bacteria within a fibrin network which may prevent systemic bacterial dissemination. In order to investigate if the FXIII-mediated entrapment of S. pyogenes also influences the disease outcome we used a murine S. pyogenes M1 skin and soft tissue infection model. Here, we demonstrate that a lack of FXIII leads to prolonged clotting times, increased signs of inflammation, and elevated bacterial dissemination. Moreover, FXIII-deficient mice show an impaired survival when compared with wildtype animals. Additionally, local reconstitution of FXIII-deficient mice with a human FXIII-concentrate (Fibrogammin ® P) could reduce the systemic complications, suggesting a protective role for FXIII during early S. pyogenes skin infection. FXIII therefore might be a possible therapeutically application to support the early innate immune response during skin infections caused by S. pyogenes. Copyright © 2016 Elsevier GmbH. All rights reserved.

FOREWORD: The 12th International Workshop on Desorption Induced by Electronic Transitions (DIET XII) (Pine Mountain, Georgia, USA, 19-23 April 2009) The 12th International Workshop on Desorption Induced by Electronic Transitions (DIET XII) (Pine Mountain, Georgia, USA, 19-23 April 2009)

NASA Astrophysics Data System (ADS)

Orlando, Thomas M.; Diebold, Ulrike

2010-03-01

The 12th International Workshop on Desorption Induced by Electronic Transitions (DIET XII) took place from 19-23 April 2009 in Pine Mountain, Georgia, USA. This was the 12th conference in a strong and vibrant series, which dates back to the early 1980s. DIET XII continued the tradition of exceptional interdisciplinary science and focused on the study of desorption and dynamics induced by electronic excitations of surfaces and interfaces. The format involved invited lectures, contributed talks and a poster session on the most recent developments and advances in this area of surface physics. The Workshop International Steering Committee and attendees wish to dedicate DIET XII to the memory of the late Professor Theodore (Ted) Madey. Ted was one of the main pioneers of this field and was one of the primary individuals working to keep this area of science exciting and adventurous. His overall contributions to surface science were countless and his contributions to the DIET field and community were enormous. He is missed and remembered by many friends and colleagues throughout the world. The papers collected in this issue cover many of the highlights of DIET XII. Topics include ultrafast electron transfer at surfaces and interfaces, quantum and spatially resolved mapping of surface dynamics and desorption, photon-, electron- and ion-beam induced processes at complex interfaces, the role of non-thermal desorption in astrochemistry and astrophysics and laser-/ion-based methods of examining soft matter and biological media. Although the workshop attracted many scientists active in the general area of non-thermal surface processes, DIET XII also attracted many younger scientists (i.e., postdoctoral fellows, advanced graduate students, and a select number of advanced undergraduate students). This field has had an impact in a number of areas including nanoscience, device physics, astrophysics, and now biophysics. We believe that this special issue of Journal of Physics

Proceedings of the XIII International School and Symposium on Synchrotron Radiation in Natural Science 2016, Ustroń-Jaszowiec, Poland

NASA Astrophysics Data System (ADS)

Kozak, Maciej; Kwiatek, Wojciech M.; Piszora, Paweł

2017-11-01

This special issue of Nuclear Instruments and Methods in Physics Research Section B of Nuclear Instruments and Methods in Physics Research was prepared to present recent achievements in synchrotron radiation science and mark the 25th anniversary of the Polish Synchrotron Radiation Society (PSRS) which fell in 2016. It presents selected papers submitted after the 13th International School and Symposium on Synchrotron Radiation in Natural Science (ISSRNS 2016) which was organized by PSRS in cooperation with the Adam Mickiewicz University. It is worth noting that PSRS is probably one of the earliest founded scientific societies focused on promoting the use of synchrotron radiation research (for details visit the PSRS home page: http://www.synchrotron.org.pl.

Double-stabilized neurotensin analogues as potential radiopharmaceuticals for NTR-positive tumors.

PubMed

García-Garayoa, Elisa; Maes, Veronique; Bläuenstein, Peter; Blanc, Alain; Hohn, Alexander; Tourwé, Dirk; Schubiger, P August

2006-05-01

Overexpression of neurotensin (NT) receptors in exocrine pancreatic cancer and other neuroendocrine cancers make them interesting targets for tumor imaging and therapy. Modifications at the cleavage bonds 8-9 and 11-12 led to the synthesis of NT-XII, NT-XIII and NT-XVIII, three new stabilized analogues. (NalphaHis)Ac was coupled to the N-terminus for labeling with [(99m)Tc]-tricarbonyl. Stability was tested in vitro in human plasma and HT-29 cells. Binding to NT1 receptors and internalization/efflux were analyzed in intact HT-29 cells. Biodistribution studies were performed in nude mice bearing HT-29 xenografts. All analogues were very stable in human plasma, with half-lives of 20-21 days. Degradation in HT-29 cells was more rapid (t(1/2) of 6.5, 5 and 2.5 h for NT-XII, NT-XIII and NT-XVIII, respectively). They also showed high affinity and specificity for NT1 receptors. Bound activity was rapidly internalized at 37 degrees C. The pattern of externalization was different. NT-XII was released more slowly than NT-XIII and NT-XVIII (half of the activity still inside the cells after 24 h). Bigger differences were found in the biodistribution studies. NT-XII showed the highest tumor uptake as well as the best tumor to nontumor ratios. The modifications introduced in NT(8-13) increased plasma stability, maintaining unaffected the in vitro binding properties. The best biodistribution corresponded to NT-XII, which shows to be a good candidate for NT1 receptors overexpressing tumors. First clinical trials are ongoing.

A randomised study of perioperative esmolol infusion for haemodynamic stability during major vascular surgery; rationale and design of DECREASE-XIII.

PubMed

Bakker, E J; Ravensbergen, N J; Voute, M T; Hoeks, S E; Chonchol, M; Klimek, M; Poldermans, D

2011-09-01

This article describes the rationale and design of the DECREASE-XIII trial, which aims to evaluate the potential of esmolol infusion, an ultra-short-acting beta-blocker, during surgery as an add-on to chronic low-dose beta-blocker therapy to maintain perioperative haemodynamic stability during major vascular surgery. A double-blind, placebo-controlled, randomised trial. A total of 260 vascular surgery patients will be randomised to esmolol or placebo as an add-on to standard medical care, including chronic low-dose beta-blockers. Esmolol is titrated to maintain a heart rate within a target window of 60-80 beats per minute for 24 h from the induction of anaesthesia. Heart rate and ischaemia are assessed by continuous 12-lead electrocardiographic monitoring for 72 h, starting 1 day prior to surgery. The primary outcome measure is duration of heart rate outside the target window during infusion of the study drug. Secondary outcome measures will be the efficacy parameters of occurrence of cardiac ischaemia, troponin T release, myocardial infarction and cardiac death within 30 days after surgery and safety parameters such as the occurrence of stroke and hypotension. This study will provide data on the efficacy of esmolol titration in chronic beta-blocker users for tight heart-rate control and reduction of ischaemia in patients undergoing vascular surgery as well as data on safety parameters. Copyright © 2011 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

The in vivo effect of fibrinogen and factor XIII on clot formation and fibrinolysis in Glanzmann's thrombasthenia.

PubMed

Shenkman, Boris; Livnat, Tami; Misgav, Mudi; Budnik, Ivan; Einav, Yulia; Martinowitz, Uriel

2012-01-01

Glanzmann's thrombasthenia (GT) is characterized by increased bleeding risk. The treatment options in GT are limited. The aim of this study was to test the effect of GT blood supplementation with fibrinogen and factor XIII on thrombin generation, blood clotting, and fibrinolysis. Whole blood samples of GT patients and normal donors treated with eptifibatide (GT model) were subjected to clotting by CaCl(2) and tissue factor. Thrombin generation was measured in platelet-rich plasma. Clot formation and tPA-induced fibrinolysis were evaluated in whole blood by rotation thromboelastometry (ROTEM). Blood was supplemented with fibrinogen (3 g/L) and/or FXIII (2 IU/mL). Thrombin generation analysis of blood derived from GT model and GT patients revealed decreased endogenous thrombin potential and peak height and extended lag time compared to control. However, this method was not sensitive to blood spiking with fibrinogen and FXIII. ROTEM revealed lower maximum clot firmness (MCF) and area under curve (AUC) in the blood of GT model and GT patients. In the absence of exogenous tPA, blood spiking with fibrinogen markedly enhanced clot quality while FXIII had no effect. Combination of fibrinogen and FXIII did not add to the effect of fibrinogen. In contrast, by the addition of tPA, both fibrinogen and FXIII separately and, to more extent, in combination enhanced clot quality as well as resistance against tPA-induced fibrinolysis (increasing MCF, AUC, and lysis onset time). In conclusion, fibrinogen and FXIII exerted stimulation of blood clotting and inhibition of fibrinolysis. Treating normal blood with eptifibatide mimics the changes of coagulopathy in GT blood.

Public health. Gates Foundation on big funding spree.

PubMed

Hagmann, M

2000-08-11

The Bill and Melinda Gates Foundation dished up $200 million in grants for scientists in various fields late last month, including research into malaria and tuberculosis. The foundation kicked off its spending spree in mid-July at the XIII International AIDS Conference in Durban, South Africa, by announcing several AIDS/HIV-related grants totaling $90 million.

Full-Authority Fault-Tolerant Electronic Engine Control System for Variable Cycle Engines.

DTIC Science & Technology

1982-04-01

single internally self-checked VLSI micro - processor . The selected configuration is an externally checked pair of com- mercially available...Electronic Engine Control FPMH Failures per Million Hours FTMP Fault Tolerant Multi- Processor FTSC Fault Tolerant Spaceborn Computer GRAMP Generalized...Removal * MTBR Mean Time Between Repair MTTF Mean Time to Failure xiii List of Abbreviations (continued) - NH High Pressure Rotor Speed O&S Operating

Employing Replay Connectors for SIEM Operator Education

DTIC Science & Technology

2013-09-01

BLANK xiii LIST OF ACRONYMS AND ABBREVIATIONS CORR Correlation Optimized Retention and Retrieval CII Critical Information Infrastructure GLBA...vast distances is now quicker and easier with the advancement in mobile computing devices and more ubiquitous connectivity and bandwidth. As a result...breakdown of the Critical Information Infrastructure (CII) is one of the core risks facing the international economy. The World Economic Forum

Factor XIII in plasma, but not in platelets, mediates red blood cell retention in clots and venous thrombus size in mice

PubMed Central

Martin, Sara M.; Holle, Lori A.; Cooley, Brian C.; Flick, Matthew J.

2018-01-01

The transglutaminase factor XIII (FXIII) stabilizes clots against mechanical and biochemical disruption and is essential for hemostasis. In vitro and in vivo models of venous thrombosis demonstrate that FXIII mediates clot size by promoting red blood cell (RBC) retention. However, the key source of FXIII and whether FXIII activity can be reduced to suppress thrombosis without imposing deleterious hemostatic consequences are 2 critical unresolved questions. FXIII is present in multiple compartments, including plasma (FXIIIplasma) as a heterotetramer of A2 and B2 subunits and platelets (FXIIIplt) as an A2 homodimer. We determined the role of the FXIII compartment and level in clot contraction, composition, and size in vitro and using in vivo models of hemostasis and venous thrombosis. Reducing overall FXIII levels decreased whole blood clot weight but did not alter thrombin generation or contraction of platelet-rich plasma clots. In reconstituted platelet-rich plasma and whole blood clot contraction assays, FXIIIplasma, but not FXIIIplt, produced high-molecular-weight fibrin crosslinks, promoted RBC retention, and increased clot weights. Genetically imposed reduction of FXIII delayed FXIII activation and fibrin crosslinking, suggesting FXIII levels mediate the kinetics of FXIII activation and activity and that the timing of these processes is a critical determinant of RBC retention during clot formation and contraction. A 50% reduction in FXIIIplasma produced significantly smaller venous thrombi but did not increase bleeding in tail transection or saphenous vein puncture models in vivo. Collectively, these findings suggest that partial FXIII reduction may be a therapeutic strategy for reducing venous thrombosis. PMID:29344582

Factor XIII in plasma, but not in platelets, mediates red blood cell retention in clots and venous thrombus size in mice.

PubMed

Kattula, Sravya; Byrnes, James R; Martin, Sara M; Holle, Lori A; Cooley, Brian C; Flick, Matthew J; Wolberg, Alisa S

2018-01-09

The transglutaminase factor XIII (FXIII) stabilizes clots against mechanical and biochemical disruption and is essential for hemostasis. In vitro and in vivo models of venous thrombosis demonstrate that FXIII mediates clot size by promoting red blood cell (RBC) retention. However, the key source of FXIII and whether FXIII activity can be reduced to suppress thrombosis without imposing deleterious hemostatic consequences are 2 critical unresolved questions. FXIII is present in multiple compartments, including plasma (FXIII plasma ) as a heterotetramer of A 2 and B 2 subunits and platelets (FXIII plt ) as an A 2 homodimer. We determined the role of the FXIII compartment and level in clot contraction, composition, and size in vitro and using in vivo models of hemostasis and venous thrombosis. Reducing overall FXIII levels decreased whole blood clot weight but did not alter thrombin generation or contraction of platelet-rich plasma clots. In reconstituted platelet-rich plasma and whole blood clot contraction assays, FXIII plasma , but not FXIII plt , produced high-molecular-weight fibrin crosslinks, promoted RBC retention, and increased clot weights. Genetically imposed reduction of FXIII delayed FXIII activation and fibrin crosslinking, suggesting FXIII levels mediate the kinetics of FXIII activation and activity and that the timing of these processes is a critical determinant of RBC retention during clot formation and contraction. A 50% reduction in FXIII plasma produced significantly smaller venous thrombi but did not increase bleeding in tail transection or saphenous vein puncture models in vivo. Collectively, these findings suggest that partial FXIII reduction may be a therapeutic strategy for reducing venous thrombosis.

Integrated Fusion, Performance Prediction, and Sensor Management for Automatic Target Exploitation

DTIC Science & Technology

2007-05-30

with large region of attraction about the true minimum. The physical optics models provide features for high confidence identification of stationary...the detection test are used to estimate 3D object scattering; multiple images can be noncoherently combined to reconstruct a more complete object...Proc. SPIE Algorithms for Synthetic Aper- ture Radar Imagery XIII, The International Society for Optical Engineering, April 2006. [40] K. Varshney, M. C

Screening cleavage of Factor XIII V34X Activation Peptides by thrombin mutants: A strategy for controlling fibrin architecture.

PubMed

Jadhav, Madhavi A; Goldsberry, Whitney N; Zink, Sara E; Lamb, Kelsey N; Simmons, Katelyn E; Riposo, Carmela M; Anokhin, Boris A; Maurer, Muriel C

2017-10-01

In blood coagulation, thrombin converts fibrinogen into fibrin monomers that polymerize into a clot network. Thrombin also activates Factor XIII by cleaving the R37-G38 peptide bond of the Activation Peptide (AP) segment. The resultant transglutaminase introduces covalent crosslinks into the fibrin clot. A strategy to modify clot architecture would be to design FXIII AP sequences that are easier or more difficult to be thrombin-cleaved thus controlling initiation of crosslinking. To aid in this design process, FXIII V34X (28-41) Activation Peptides were kinetically ranked for cleavage by wild-type thrombin and several anticoagulant mutants. Thrombin-catalyzed hydrolysis of aromatic FXIII F34, W34, and Y34 APs was compared with V34 and L34. Cardioprotective FXIII L34 remained the variant most readily cleaved by wild-type thrombin. The potent anticoagulant thrombins W215A and W215A/E217A (missing a key substrate platform for binding fibrinogen) were best able to hydrolyze FXIII F34 and W34 APs. Thrombin I174A and L99A could effectively accommodate FXIII W34 and Y34 APs yielding kinetic parameters comparable to FXIII AP L34 with wild-type thrombin. None of the aromatic FXIII V34X APs could be hydrolyzed by thrombin Y60aA. FXIII F34 and W34 are promising candidates for FXIII - anticoagulant thrombin systems that could permit FXIII-catalyzed crosslinking in the presence of reduced fibrin formation. By contrast, FXIII Y34 with thrombin (Y60aA or W215A/E217A) could help assure that both fibrin clot formation and protein crosslinking are hindered. Regulating the activation of FXIII is predicted to be a strategy for helping to control fibrin clot architecture and its neighboring environments. Copyright © 2017 Elsevier B.V. All rights reserved.

Relative effects of plasma, fibrinogen concentrate, and factor XIII on ROTEM coagulation profiles in an in vitro model of massive transfusion in trauma.

PubMed

Schmidt, David E; Halmin, Märit; Wikman, Agneta; Östlund, Anders; Ågren, Anna

2017-10-01

Massive traumatic haemorrhage is aggravated through the development of trauma-induced coagulopathy, which is managed by plasma transfusion and/or fibrinogen concentrate administration. It is yet unclear whether these treatments are equally potent in ensuring adequate haemostasis, and whether additional factor XIII (FXIII) administration provides further benefits. In this study, we compared ROTEM whole blood coagulation profiles after experimental massive transfusion with different transfusion regimens in an in vitro model of dilution- and transfusion-related coagulopathy. Healthy donor blood was mixed 1 + 1 with six different transfusion regimens. Each regimen contained RBC, platelet concentrate, and either fresh frozen plasma (FFP) or Ringer's acetate (RA). The regimens were further augmented through addition of a low- or medium-dose fibrinogen concentrate and FXIII. Transfusion with FFP alone was insufficient to maintain tissue-factor activated clot strength, coincidental with a deficiency in fibrin-based clot strength. Fibrinogen concentrate conserved, but did not improve coagulation kinetics and overall clot strength. Only combination therapy with FFP and low-dose fibrinogen concentrate improved both coagulation kinetics and fibrin-based clot strength. Administration of FXIII did not result in an improvement of clot strength. In conclusion, combination therapy with both FFP and low-dose fibrinogen concentrate improved clotting time and produced firm clots, representing a possible preferred first-line regimen to manage trauma-induced coagulopathy when RBC and platelets are also transfused. Further research is required to identify optimal first-line transfusion fluids for massive traumatic haemorrhage.

76 FR 48563 - Medicare and Medicaid Programs; Quarterly Listing of Program Issuances-January Through March 2011...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-08

...-7205 Ventricular Assist Device (Destination Therapy) Facilities. XIII Medicare-Approved Lung JoAnna...-Approved Ventricular Assist Device (Destination Therapy) Facilities, Addendum XIII: Lung Volume Reduction...-Approved Ventricular Assist Device (Destination Therapy) Facilities (January Through March 2011) Addendum...

Air Quality Side Event Proposal November 2016 GEO XIII ...

EPA Pesticide Factsheets

The Group on Earth Observations (GEO), which EPA has participated in since 2003, has put out a call for Side Events for its thirteenth annual international Plenary Meeting which is in St. Petersburg, Russia this year during November, 2016. EPA has put on Side Events on Air Quality and Health observational systems at eight of the previous Plenaries. This document is a Side Event proposal regarding air quality, health and next generation monitoring and observations techniques. It is submitted to the GEO Secretariat for consideration. If accepted, there will likely be presentations by EPA and NASA, other GEO Member Countries and UNEP and other GEO Participating Organizations at the Side Event. It is an opportunity to share scientific and technological advances in this area and build partnerships and collaboration. The Group on Earth Observations (GEO), which EPA has participated in since 2003, has put out a call for Side Events for its thirteenth annual international Plenary Meeting which is in St. Petersburg, Russia this year during November, 2016. EPA has put on Side Events on Air Quality and Health observational systems at eight of the previous Plenaries. This document is a Side Event proposal regarding air quality, health and next generation monitoring and observations techniques.  It is submitted to the GEO Secretariat for consideration. If accepted, there will likely be presentations by EPA and NASA, other GEO Member Countries and UNEP and other GEO P

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow

PubMed Central

Mousa, Aisha; Cui, Cui; Song, Aimei; Myneni, Vamsee D; Sun, Huifang; Li, Jin Jin; Murshed, Monzur; Melino, Gerry; Kaartinen, Mari T

2017-01-01

Appropriate bone mass is maintained by bone-forming osteoblast and bone-resorbing osteoclasts. Mesenchymal stem cell (MSC) lineage cells control osteoclastogenesis via expression of RANKL and OPG (receptor activator of nuclear factor κB ligand and osteoprotegerin), which promote and inhibit bone resorption, respectively. Protein crosslinking enzymes transglutaminase 2 (TG2) and Factor XIII-A (FXIII-A) have been linked to activity of myeloid and MSC lineage cells; however, in vivo evidence has been lacking to support their function. In this study, we show in mice that TG2 and FXIII-A control monocyte-macrophage cell differentiation into osteoclasts as well as RANKL production in MSCs and in adipocytes. Long bones of mice lacking TG2 and FXIII-A transglutaminases, show compromised biomechanical properties and trabecular bone loss in axial and appendicular skeleton. This was caused by increased osteoclastogenesis, a cellular phenotype that persists in vitro. The increased potential of TG2 and FXIII-A deficient monocytes to form osteoclasts was reversed by chemical inhibition of TG activity, which revealed the presence of TG1 in osteoclasts and assigned different roles for the TGs as regulators of osteoclastogenesis. TG2- and FXIII-A-deficient mice had normal osteoblast activity, but increased bone marrow adipogenesis, MSCs lacking TG2 and FXIII-A showed high adipogenic potential and significantly increased RANKL expression as well as upregulated TG1 expression. Chemical inhibition of TG activity in the null cells further increased adipogenic potential and RANKL production. Altered differentiation of TG2 and FXIII-A null MSCs was associated with plasma fibronectin (FN) assembly defect in cultures and FN retention in serum and marrow in vivo instead of assembly into bone. Our findings provide new functions for TG2, FXIII-A and TG1 in bone cells and identify them as novel regulators of bone mass, plasma FN homeostasis, RANKL production and myeloid and MSC cell

Establishment of a prenatal diagnosis schedule as part of a prophylaxis program of factor XIII deficiency in the southeast of Iran.

PubMed

Naderi, Majid; Reykande, Samira Esmaeili; Dorgalaleh, Akbar; Alizadeh, Shaban; Tabibian, Shadi; Einollahi, Nahid; Moghaddam, Ebrahim Miri

2016-01-01

Factor XIII deficiency (FXIIID) is an extremely rare bleeding disorder with a prevalence of 1 in 3 million in the general population. Compared to its global incidence, it has the greatest prevalence in Sistan and Baluchistan Province in the southeast of Iran. The high incidence of FXIIID in this region causes a high rate of morbidity and mortality among the affected individuals because of life-threatening episodes such as central nervous system (CNS) bleeding, umbilical cord bleeding, as well as miscarriage. CNS bleeding leads to a considerable number of neurological and behavioral complications. Therefore, we have designed an established prenatal diagnosis (PND) program to prevent the increasing incidence of life-threatening bleeding episodes and related complications among neonates with congenital FXIIID. This study was conducted from September 2013 to August 2014. A consent form was signed by the parents. Fetal sampling was done via abdominal chorionic villus sampling passage under local anesthesia and ultrasonic guidance within the first trimester of pregnancy. Fetal DNA was extracted, and PCR-restriction fragment length polymorphism was performed for the only reported mutation of FXIII (Trp187Arg) in the southeast of Iran. During the period of study, PND was performed on eight fetuses. Six fetuses were offspring of parental consanguineous marriages, and all of them had a positive family history of FXIIID. Seven out of the eight fetuses had a family member with CNS bleeding due to FXIIID. Four fetuses had a FXIIID-related death. One of the fetuses bore homozygous Trp187Arg mutation, whereas six were heterozygous, and one of the mothers gave birth to an unaffected fetus. To the best of our knowledge, PND is a possible solution to control high incidence of life-threatening episodes of FXIIID in southeast Iran.

Implementation of Leak Test Methods for the International Space Station (ISS) Elements, Systems and Components

NASA Technical Reports Server (NTRS)

Underwood, Steve; Lvovsky, Oleg

2007-01-01

The International Space Station (ISS has Qualification and Acceptance Environmental Test Requirements document, SSP 41172 that includes many environmental tests such as Thermal vacuum & Cycling, Depress/Repress, Sinusoidal, Random, and Acoustic Vibration, Pyro Shock, Acceleration, Humidity, Pressure, Electromatic Interference (EMI)/Electromagnetic Compatibility (EMCO), etc. This document also includes (13) leak test methods for Pressure Integrity Verification of the ISS Elements, Systems, and Components. These leak test methods are well known, however, the test procedure for specific leak test method shall be written and implemented paying attention to the important procedural steps/details that, if omitted or deviated, could impact the quality of the final product and affect the crew safety. Such procedural steps/details for different methods include, but not limited to: - Sequence of testing, f or example, pressurization and submersion steps for Method I (Immersion); - Stabilization of the mass spectrometer leak detector outputs fo r Method II (vacuum Chamber or Bell jar); - Proper data processing an d taking a conservative approach while making predictions for on-orbit leakage rate for Method III(Pressure Change); - Proper Calibration o f the mass spectrometer leak detector for all the tracer gas (mostly Helium) Methods such as Method V (Detector Probe), Method VI (Hood), Method VII (Tracer Probe), Method VIII(Accumulation); - Usage of visibl ility aides for Method I (Immersion), Method IV (Chemical Indicator), Method XII (Foam/Liquid Application), and Method XIII (Hydrostatic/Visual Inspection); While some methods could be used for the total leaka ge (either internal-to-external or external-to-internal) rate requirement verification (Vacuum Chamber, Pressure Decay, Hood, Accumulation), other methods shall be used only as a pass/fail test for individual joints (e.g., welds, fittings, and plugs) or for troubleshooting purposes (Chemical Indicator, Detector Probe

Congenital Myasthenic Syndrome Type 19 Is Caused by Mutations in COL13A1, Encoding the Atypical Non-fibrillar Collagen Type XIII α1 Chain.

PubMed

Logan, Clare V; Cossins, Judith; Rodríguez Cruz, Pedro M; Parry, David A; Maxwell, Susan; Martínez-Martínez, Pilar; Riepsaame, Joey; Abdelhamed, Zakia A; Lake, Alice V R; Moran, Maria; Robb, Stephanie; Chow, Gabriel; Sewry, Caroline; Hopkins, Philip M; Sheridan, Eamonn; Jayawant, Sandeep; Palace, Jacqueline; Johnson, Colin A; Beeson, David

2015-12-03

The neuromuscular junction (NMJ) consists of a tripartite synapse with a presynaptic nerve terminal, Schwann cells that ensheathe the terminal bouton, and a highly specialized postsynaptic membrane. Synaptic structural integrity is crucial for efficient signal transmission. Congenital myasthenic syndromes (CMSs) are a heterogeneous group of inherited disorders that result from impaired neuromuscular transmission, caused by mutations in genes encoding proteins that are involved in synaptic transmission and in forming and maintaining the structural integrity of NMJs. To identify further causes of CMSs, we performed whole-exome sequencing (WES) in families without an identified mutation in known CMS-associated genes. In two families affected by a previously undefined CMS, we identified homozygous loss-of-function mutations in COL13A1, which encodes the alpha chain of an atypical non-fibrillar collagen with a single transmembrane domain. COL13A1 localized to the human muscle motor endplate. Using CRISPR-Cas9 genome editing, modeling of the COL13A1 c.1171delG (p.Leu392Sfs(∗)71) frameshift mutation in the C2C12 cell line reduced acetylcholine receptor (AChR) clustering during myotube differentiation. This highlights the crucial role of collagen XIII in the formation and maintenance of the NMJ. Our results therefore delineate a myasthenic disorder that is caused by loss-of-function mutations in COL13A1, encoding a protein involved in organization of the NMJ, and emphasize the importance of appropriate symptomatic treatment for these individuals. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

Regulation of plasma factor XIII levels in healthy individuals; a major impact by subunit B intron K c.1952+144 C>G polymorphism.

PubMed

Mezei, Zoltán A; Katona, Éva; Kállai, Judit; Bereczky, Zsuzsanna; Molnár, Éva; Kovács, Bettina; Ajzner, Éva; Bagoly, Zsuzsa; Miklós, Tünde; Muszbek, László

2016-12-01

The regulation of plasma factor XIII (FXIII) levels in healthy individuals has been only partially explored. The identification of major non-genetic and genetic regulatory factors might provide important information on the contribution of FXIII to the risk of cardio/cerebrovascular diseases. To determine the effect of age, smoking, BMI, fibrinogen concentration on plasma FXIII activity, complex FXIII antigen (FXIII-A 2 B 2 ) and total FXIII-B subunit (tFXIII-B) level, to correlate FXIII-B level with the other two FXIII parameters and to assess the variation of FXIII levels in carriers of major FXIII subunit polymorphisms. 268 healthy individuals were enrolled in the study. FXIII activity was measured by the ammonia release assay; FXIII-A 2 B 2 and tFXIII-B were determined by ELISAs. FXIII-A p.Val34Leu, FXIII-B p.His95Arg and FXIII-B intron K c.1952+144 C>G polymorphisms were identified by RT-PCR using melting point analysis with fluorescence resonance energy transfer detection. All investigated FXIII parameters showed significant positive correlation with age and fibrinogen level; gender and BMI influenced only tFXIII-B. A highly significant positive correlation was demonstrated between tFXIII-B and the other FXIII parameters. FXIII-A p.Val34Leu polymorphism had only slight, if any effect on FXIII levels. The FXIII-B Arg95 allele moderately increased all three FXIII parameters, but the effect became statistically significant only after adjustment. The FXIII-B intron K G allele drastically decreased FXIII levels, and it seemed to be in synergism with the FXIII-A Leu34 allele. Plasma FXIII levels are subjected to multifactorial regulation, in which age, fibrinogen level and FXIII-B intron K polymorphism are major determinants. Copyright © 2016 Elsevier Ltd. All rights reserved.

Activation of tissue kallikrein-kininogen-kinin system in rabbit skin by a fraction isolated from Phoneutria nigriventer (armed spider) venom.

PubMed

Antunes, E; Marangoni, R A; Giglio, J R; Brain, S D; de Nucci, G

1993-11-01

Phoneutria nigriventer venom was fractionated by gel filtration followed by ion-exchange chromatography from which 16 fractions (I-XVI) were obtained and assayed in rabbit skin in order to identify those responsible for the increased vascular permeability observed with the whole venom. The fractions, and control mediators (tissue kallikrein, bradykinin and histamine) were intradermally injected in male New Zealand white rabbits. Local oedema formation was measured as the local accumulation of i.v. injected 125I-human serum albumin into skin sites. Fraction XIII was the only fraction assayed which significantly induced oedema formation. Fraction XIII-induced oedema was greatly reduced by either the protease inhibitor aprotinin or the bradykinin B2 receptor antagonist D-Arg,[Hyp3,Thi5,8D-Phe7]-Bk, whereas the plasma kallikrein inhibitor soybean trypsin inhibitor failed to significantly affect this oedematogenic response. The kininase II inhibitor captopril markedly potentiated fraction XIII-induced oedema. Our results indicate that the increased vascular permeability induced by fraction XIII is due to local generation of kinins in response to tissue (but not plasma) kallikrein-kinin system activation.

An experimental approach to manufacturing technology of historical glass (XIII-XV centuries). Comparison with current glassmaking technology.

NASA Astrophysics Data System (ADS)

Tarrago, Mariona; Gimeno, Domingo; Bazzocchi, Flavia; Garcia-Valles, Maite; Martinez, Salvador

2015-04-01

One of the major and less explored issues in the characterization of historical glasses is the determination of their viscosity as a function of temperature in order to constrain technological aspects of glass production. Until now, assumptions on temperatures have been based on mathematical models based on chemical compositions. Hence, the topic of this work is to explore the technology of stained glass production related to the workability and melting process of the glass by experimental laboratory measurements. This work presents the analysis of viscosity of glasses from different historical sites and chemical compositions: four from Santes Creus (Tarragona, XIII century), two of classical medieval stained glass window from Santa Maria de Pedralbes (Barcelona, mid XIV century), and three of evolved late-medieval type from Santa Maria del Mar (Barcelona first half of XV century), and one sample of soda-lime industrial glass by means of Hot-Stage Microscopy and glass transformation temperature Tg by dilatometry. These data are then compared to the predictions on theoretical viscosity obtained from mathematical models based on chemical composition. These samples are classified according to their major modifier in: Na-rich (12-17% of Na2O, between 65-77% of SiO2 and less than 3 % of K2O); Ca-rich (29% of CaO, 54% of SiO2, 4% of K2O, and 4% of Na2O); K-Ca-rich (17 to 21% of K2O, more than 14% of CaO, 49-55% of SiO2and less than 2% of Na2O); Na-Ca-rich (12-14% of Na2O, 9-15% of CaO, 57-71% of SiO2 and < 6% of K2O). Glass transition temperature (Tg) is correlated to chemical composition: 464-492 °C for Na-rich, 645 °C for Ca-rich, 582-586 °C for K-Ca-rich and 497-542 °C for Na-Ca-rich glasses. Experimental viscosity-temperature curves are traced using Tg and fixed viscosity points measured by Hot-Stage microscopy (according to German standard 51730) in order to provide more accurate insight into the phases of glass production process (melting, working, conditioning

Central nervous system bleeding in pediatric patients with factor XIII deficiency: a study on 23 new cases.

PubMed

Naderi, Majid; Alizadeh, Shaban; Kazemi, Ahmad; Tabibian, Shadi; Zaker, Farhad; Bamedi, Taregh; Kashani Khatib, Zahra; Dorgalaleh, Akbar

2015-03-01

Factor XIII (FXIII) deficiency is an extremely rare bleeding disorder, which has the highest incidence in Sistan and Baluchistan Province in Iran, compared to its overall incidence around the world. This disorder has different clinical manifestations ranging from mild bleeding tendency to lethal bleeding episodes including central nervous system (CNS) hemorrhage. The aim of this study was to evaluate the demographic data, pattern of CNS bleeding, and the role of plasminogen activator inhibitor-1 (PAI-1) (PAI-1) 4G/5G and thrombin activatable fibrinolysis inhibitor (TAFI) Thr325Ile polymorphisms in intracranial and extracranial hemorrhages in 23 new cases of FXIII-deficient subjects. This case-control study was conducted on 23 FXIII-deficient patients with CNS bleeding episodes and 23 patients as the control group with FXIII deficiency but without any history of CNS bleeding. Initially, to confirm the molecular defect, both groups were evaluated for the most frequently reported mutation of FXIII (Trp187Arg mutation) in a previous study in Sistan and Baluchistan Province. Then, demographic data, clinical manifestations, and pattern of CNS bleeding were determined. Eventually, the patients were assessed for PAI-14G/5G and TAFI Thr325Ile polymorphisms. The results of this study revealed that all the subjects (including the case and control groups) were homozygous for Trp187Arg mutation. Nineteen patients (82.6%) had intracranial hemorrhage (ICH) and four patients (17.4%) had extracranial hemorrhage (ECH). Intraparenchymal hemorrhage was the most common form of ICH (89.5%), and epidural hemorrhage was observed in two patients (10.5%). Anatomic regions in patients with intraparenchymal hemorrhage were temporal in six (35.3%), occipital in four (23.5%), diffused intraparenchymal in four (23.5%), temporal-occipital in two (11.8%), and subdural with temporal in one (5.9%) patient. We found that in the case group, 14 patients (60.8%) were homozygous for TAFI Thr325Ile

Intracranial Hemorrhage: A Devastating Outcome of Congenital Bleeding Disorders-Prevalence, Diagnosis, and Management, with a Special Focus on Congenital Factor XIII Deficiency.

PubMed

Alavi, Seyed Ezatolla Rafiee; Jalalvand, Masumeh; Assadollahi, Vahideh; Tabibian, Shadi; Dorgalaleh, Akbar

2018-04-01

Intracranial hemorrhage (ICH) is a medical emergency. In congenital bleeding disorders, ICH is a devastating presentation accompanied with a high rate of morbidity and mortality. The prevalence of ICH is highly variable among congenital bleeding disorders, with the highest incidence observed in factor (F) XIII deficiency (FXIIID) (∼30%). This life-threatening presentation is less common in afibrinogenemia, FVIII, FIX, FVII, and FX deficiencies, and is rare in severe FV and FII deficiencies, type 3 von Willebrand disease and inherited platelet function disorders (IPFDs). In FXIIID, this diathesis most often occurs after trauma in children, whereas spontaneous ICH is more frequent in adults. About 15% of patients with FXIIID and ICH die; the bleeding causes 80% of deaths in this coagulopathy. Although in FXIIID, the bleed most commonly is intraparenchymal (> 90%), epidural, subdural, and subarachnoid hemorrhages also have been reported, albeit rarely. As this life-threatening bleeding causes neurological complications, early diagnosis can prevent further expansion of the hematoma and secondary damage. Neuroimaging plays a crucial role in the diagnosis of ICH, but signs and symptoms in patients with severe FXIIID should trigger replacement therapy even before establishment of the diagnosis. Although a high dose of FXIII concentrate can reduce the rate of morbidity and mortality of ICH in FXIIID, it may occasionally trigger inhibitor development, thus complicating ICH management and future prophylaxis. Nevertheless, replacement therapy is the mainstay of treatment for ICH in FXIIID. Neurosurgery is performed in patients with FXIIID and epidural hematoma and a hemorrhage diameter exceeding 2 cm or a volume of ICH is more than 30 cm 3 . Contact sports are not recommended in people with FXIIID as they can elicit ICH. However, a considerable number of safe sports and activities have been suggested to have more benefits than dangers for patients with congenital bleeding

Identification of a 'Candidatus Phytoplasma hispanicum'-related strain, associated with yellows-type diseases, in smoke-tree sharpshooter (Homalodisca liturata Ball).

PubMed

Servín-Villegas, Rosalía; Caamal-Chan, Maria Goretty; Chavez-Medina, Alicia; Loera-Muro, Abraham; Barraza, Aarón; Medina-Hernández, Diana; Holguín-Peña, Ramón Jaime

2018-04-11

The 16SrXIII group from phytoplasma bacteria were identified in salivary glands from Homalodisca liturata, which were collected in El Comitán on the Baja California peninsula in Mexico. We were able to positively identify 15 16S rRNA gene sequences with the corresponding signature sequence of 'CandidatusPhytoplasma' (CAAGAYBATKATGTKTAGCYGGDCT) and in silico restriction fragment length polymorphism (RFLP) profiles (F value estimations) coupled with a phylogenetic analysis to confirm their relatedness to 'CandidatusPhytoplasma hispanicum', which in turn belongs to the 16SrXIII group. A restriction analysis was carried out with AluI and EcoRI to confirm that the five sequences belongs to subgroup D. The rest of the sequences did not exhibit any known RFLP profile related to a subgroup reported in the 16SrXIII group.

PREFACE: Recent Developments in Gravity (NEB XIII)

NASA Astrophysics Data System (ADS)

Stergioulas, N.; Tsagas, C.

2009-09-01

Gravitational physics has been at the forefront of research in both Astrophysics and Cosmology. Since 1984, relativists in Greece have organized (every two years) a conference that follows progress in this field. The 13th Conference on Recent Developments in Gravity was organized by the relativity group at the Department of Physics of the University of Thessaloniki, in June 2008. This volume contains the written versions as well as extensions of most of the talks delivered at that meeting. The conference was attended by more than a hundred participants, half of which came from outside Greece, while it brought together nearly all Greek researchers in the areas of relativity, gravity and cosmology. The large number of participants from abroad underlines the increasingly international character of these meetings. In Thessaloniki, the plenary talks and parallel sessions covered topics on gravitational waves, relativistic astrophysics, alternative theories of gravity, mathematical relativity, cosmology and quantum gravity. The plenary speakers were A Ashtekar (Penn-State), G Ellis (Cape Town), V Frolov (Alberta), J Hough (Glasgow), P Laguna (Penn-State), R Loll (Utrecht) and D Psaltis (Arizona). In addition, invited keynote talks were presented by N Batakis (Ioannina), T Christodoulakis (Athens), S Cotsakis (Aegean), P Kanti (Ioannina), L Perivolaropoulos (Ioannina), M Plionis (NOA-Athens), J Pullin (Louisiana), G Siopsis (Tennesee) and M Tsamparlis (Athens). The Organizing Committee of the conference comprised N Stergioulas (chair), K D Kokkotas, D Papadopoulos, C Tsagas, H Dimmelmeier, K Kleidis, K Zagouris and K Dionysopoulou while the Scientific Committee included N Spyrou (chair - Thessaloniki), P Florides (Dublin) and G Schaefer (Jena). The conference was sponsored by the Aristotle University of Thessaloniki (AUTh), the Department of Physics, the Section of Astrophysics, Astronomy and Mechanics, the Research Committee of AUTh, the Ministry of Macedonia and Thrace

Constraining Line-of-sight Confusion in the Corona Using Linearly Polarized Observations of the Infrared FeXIII 1075nm and SiX 1430nm Emission Lines

NASA Astrophysics Data System (ADS)

Dima, G. I.; Kuhn, J. R.; Berdyugina, S.

2017-12-01

Measurements of the coronal magnetic field are difficult because of the intrinsically faint emission of coronal plasma and the large spurious background due to the bright solar disk. This work addresses the problem of resolving the confusion of the line-of-sight (LOS) integration through the optically-thin corona being observed. Work on developing new measuring techniques based on single-point inversions using the Hanle effect has already been described (Dima et al. 2016). It is important to develop a technique to assess when the LOS confusion makes comparing models and observations problematic. Using forward integration of synthetic emission through magnetohydrodynamic (MHD) models together with simultaneous linearly polarized observations of the FeXIII 1075nm and SiX 1430nm emission lines allows us to assess LOS confusion. Since the lines are both in the Hanle saturated regime their polarization angles are expected to be aligned as long as the gas is sampling the same magnetic field. If significant contributions to the emission is taking place from different regions along the LOS due to the additive nature of the polarized brightness the measured linear polarization between the two lines will be offset. The size of the resolution element is important for this determination since observing larger coronal regions will confuse the variation along the LOS with that in the plane-of-sky. We also present comparisons between synthetic linearly polarized emission through a global MHD model and observations of the same regions obtained using the 0.5m Scatter-free Observatory for Limb Active Regions and Coronae (SOLARC) telescope located on Haleakala, Maui. This work is being done in preparation for the type of observations that will become possible when the next generation 4m DKIST telescope comes online in 2020.

Evaluation of a Salmonella Strain Lacking the Secondary Messenger C-di-GMP and RpoS as a Live Oral Vaccine

PubMed Central

García, Begoña; Gil, Carmen; García-Ona, Enrique; Burgui, Saioa; Casares, Noelia; Hervás-Stubbs, Sandra; Lasarte, Juan José; Lasa, Iñigo

2016-01-01

Salmonellosis is one of the most important bacterial zoonotic diseases transmitted through the consumption of contaminated food, with chicken and pig related products being key reservoirs of infection. Although numerous studies on animal vaccination have been performed in order to reduce Salmonella prevalence, there is still a need for an ideal vaccine. Here, with the aim of constructing a novel live attenuated Salmonella vaccine candidate, we firstly analyzed the impact of the absence of cyclic-di-GMP (c-di-GMP) in Salmonella virulence. C-di-GMP is an intracellular second messenger that controls a wide range of bacterial processes, including biofilm formation and synthesis of virulence factors, and also modulates the host innate immune response. Our results showed that a Salmonella multiple mutant in the twelve genes encoding diguanylate cyclase proteins that, as a consequence, cannot synthesize c-di-GMP, presents a moderate attenuation in a systemic murine infection model. An additional mutation of the rpoS gene resulted in a synergic attenuating effect that led to a highly attenuated strain, referred to as ΔXIII, immunogenic enough to protect mice against a lethal oral challenge of a S. Typhimurium virulent strain. ΔXIII immunogenicity relied on activation of both antibody and cell mediated immune responses characterized by the production of opsonizing antibodies and the induction of significant levels of IFN-γ, TNF-α, IL-2, IL-17 and IL-10. ΔXIII was unable to form a biofilm and did not survive under desiccation conditions, indicating that it could be easily eliminated from the environment. Moreover, ΔXIII shows DIVA features that allow differentiation of infected and vaccinated animals. Altogether, these results show ΔXIII as a safe and effective live DIVA vaccine. PMID:27537839

A comparison of the mechanical, kinetic, and biochemical properties of fibrin clots formed with two different fibrin sealants.

PubMed

Hickerson, William L; Nur, Israel; Meidler, Roberto

2011-01-01

The objective of the present study was to compare the mechanical, kinetic, and biochemical properties of fibrin clots produced using EVICEL Fibrin Sealant (Human) and TISSEEL Fibrin Sealant. The stiffness/elasticity and strength of fibrin clots formed with EVICEL and TISSEEL were assessed using applied mechanical force and thromboelastography (TEG). The factor XIII content of the fibrin clots was also evaluated. Mean Young modulus and tensile strength of the fibrin clots produced by EVICEL were significantly higher than those of clots produced by TISSEEL (P < 0.05 for both). The mean time to initial clot formation and mean time to the predefined level of clot formation were numerically shorter for EVICEL compared with TISSEEL. Furthermore, mean maximal amplitude of the clots formed with EVICEL was significantly greater than that for the clots formed with TISSEEL. Mean concentration of factor XIII for the EVICEL fibrinogen samples tested was 9 IU/ml compared with undetectable concentrations of factor XIII for the TISSEEL fibrinogen samples. Fibrin clots formed with EVICEL have a much higher resistance to stretching and tensile strength and are more capable of maintaining their structure against applied force than those formed with TISSEEL. EVICEL also allows more rapid development of fibrin clots than TISSEEL. This superior clot strength and resilience obtained with EVICEL relative to TISSEEL may be due in large part to the presence of factor XIII.

Air Quality Side Event Proposal November 2016 GEO XIII Plenary in St. Petersburg, Russia

EPA Science Inventory

The Group on Earth Observations (GEO), which EPA has participated in since 2003, has put out a call for Side Events for its thirteenth annual international Plenary Meeting which is in St. Petersburg, Russia this year during November, 2016. EPA has put on Side Events on Air Quali...

Relative ion expansion velocity in laser-produced plasmas

NASA Technical Reports Server (NTRS)

Goldsmith, S.; Moreno, J. C.; Griem, H. R.; Cohen, Leonard; Richardson, M. C.

1988-01-01

The spectra of highly ionized titanium, Ti XIII through Ti XXI, and C VI Lyman lines were excited in laser-produced plasmas. The plasma was produced by uniformly irradiating spherical glass microballoons coated with thin layers of titanium and parylene. The 24-beam Omega laser system produced short, 0.6 ns, and high-intensity, 4 x 10 to the 14th W/sq cm, laser pulses at a wavelength of 351 nm. The measured wavelength for the 2p-3s Ti XIII resonance lines had an average shift of + 0.023 A relative to the C VI and Ti XX spectral lines. No shift was found between the C VI, Ti XIX, and Ti XX lines. The shift is attributed to a Doppler effect, resulting from a difference of (2.6 + or - 0.2) x 10 to the 7th cm/s in the expansion velocities of Ti XIX and Ti XX ions compared to Ti XIII ions.

Diagnosis, clinical manifestations and management of rare bleeding disorders in Iran.

PubMed

Dorgalaleh, Akbar; Alavi, Sayed Ezatolla Rafiee; Tabibian, Shadi; Soori, Shahrzad; Moradi, Es'hagh; Bamedi, Taregh; Asadi, Mansour; Jalalvand, Masumeh; Shamsizadeh, Morteza

2017-05-01

Rare bleeding disorders (RBDs) are heterogeneous disorders, mostly inherited in an autosomal recessive pattern. Iran is a Mideast country with a high rate of consanguinity that has a high rate of RBDs. In this study, we present prevalence and clinical presentation as well as management and genetic defects of Iranian patients with RBDs. For this study, all relevant publications were searched in Medlin until 2015. Iran has the highest global incidence of factor XIII deficiency. Factor VII deficiency also is common in Iran, while factor II deficiency, with a prevalence of 1 per ∼3 million, is the rarest form of RBDs. Factor activity is available for all RBDs except for factor XIII deficiency, in which clot solubility remains as a diagnostic test. Molecular analysis of Iranian patients with RBDs revealed a few recurrent, common mutations only in patients with factor XIII deficiency, and considerable novel mutations in other RBDs. Clinical manifestations of these patients are variable and patients with factor XIII, factor X and factor VII more commonly presented severe life-threatening bleeding, while patients with combined factor V and factor VIII presented a milder phenotype. Plasma-derived products are the most common therapeutic choice in Iran, used prophylactically or on-demand for the management of these patients. Since Iran has a high rate of RBDs with life-threatening bleeding, molecular studies can be used for carrier detection and, therefore, prevention of the further expansion of these disorders and their fatal consequence.

Tabulation of comet observations.

NASA Astrophysics Data System (ADS)

Concerning comets: 1962 VIII Humason, 1971 V Toba, 1975 XI Bradfield, 1979 X Bradfield, 1980 X P/Stephan-Oterma, 1980 XI P/Encke, 1980 XIII P/Tuttle, 1981 II Panther, 1982 VI Austin, 1982 VIII P/Churyumov-Gerasimenko, 1983 V Sugano-Saigusa-Fujikawa, 1983 VII IRAS-Araki-Alcock, 1983 XIII P/Kopff, 1984 III P/Hartley-IRAS, 1985 XIII P/Giacobini-Zinner, 1985 XVII Hartley-Good, 1985 XIX Thiele, 1986 III P/Halley, 1986h P/Schwassmann-Wachmann 2, 1986j P/Comas Solá, 1986k P/Kohoutek, 1986l Wilson, 1986m P/Grigg-Skjellerup, 1986n Sorrells, 1987h P/Howell, 1987l P/Reinmuth 2, 1987m P/Brooks 2, 1987n P/Harrington, 1987p P/Borrelly, 1987r P/Reinmuth 1, 1987s Bradfield, 1987u Rudenko, 1987y Levy, 1987z P/Shoemaker-Holt, 1987b1 McNaught, 1987d1 Ichimura, 1987f1 Furuyama, 1988a Liller, 1988b Shoemaker, 1988c Maury-Phinney, 1988e Levy, P/Schwassmann-Wachmann 1.

Order XIII. Pseudonocardineae ord.nov.

USDA-ARS?s Scientific Manuscript database

The formal description of the actinobacterial higher taxon, the suborder Pseudonocardineae, is presented. The differential morphological and chemotaxonomic characteristics and diagnostic signature nucleotides from the 16S rRNA gene for the families Actinosynnemataceae and Pseudonocardiaceae in the ...

Teaching International Law: Concepts in International Relations

ERIC Educational Resources Information Center

Starbird, Caroline; Pettit, Jenny; Singleton, Laurel

2004-01-01

This book is designed to introduce students to public international law. Topics covered include international public organizations, such as the United Nations and World Trade Organization, international courts, international human rights law, international trade law, and international environmental law. The goal of each study is to examine how…

Putting third first: critical legal issues and HIV/AIDS.

PubMed

2000-01-01

On 7 July 2000, before the XIII International AIDS Conference, the Canadian HIV/AIDS Legal Network and the AIDS Law Project, South Africa held a one-day satellite meeting on legal, ethical, and human rights issues in Durban, South Africa. Entitled Putting Third First--Critical Legal Issues and HIV/AIDS, the satellite focused on legal strategies to advance the human rights of those most vulnerable to HIV/AIDS and to discrimination: people in the developing world, and people who, although they live in the industrialized world, suffer from poverty and marginalization and are at high risk of contracting HIV. The satellite grew out of the ongoing partnership between the Canadian HIV/AIDS Legal Network and the AIDS Law Project, South Africa, and was co-hosted by UNAIDS.

Simulation of Aircraft Sortie Generation Under an Autonomic Logistics System

DTIC Science & Technology

2016-12-01

56 Design of Experiment...Figure 8. Pre -flight Operations ......................................................................................... 40 Figure 9. Sortie...Critical Factors and Their Associated Levels ................................................... 57 xiii Table 18. Design of Experiment

Aerodynamic Design of Axial-flow Compressors. Volume III

NASA Technical Reports Server (NTRS)

Johnson, Irving A; Bullock, Robert O; Graham, Robert W; Costilow, Eleanor L; Huppert, Merle C; Benser, William A; Herzig, Howard Z; Hansen, Arthur G; Jackson, Robert J; Yohner, Peggy L;

77 FR 29648 - Medicare and Medicaid Programs; Quarterly Listing of Program Issuances-January Through March 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-18

... (Destination Therapy) Facilities. XIII Medicare-Approved Lung Volume Reduction Surgery JoAnna Baldwin, MS (410) 786-7205 Facilities. XIV Medicare-Approved Bariatric Surgery Facilities........ Kate Tillman, RN, MAS...

77 FR 68155 - Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-15

...-Quality Control Compliance/3rd Party CPA XII. National Foreclosure Mitigation Counseling (NFMC) Compliance Update XIII. OHTS Watch List and Overview of Organizational Assessment Review Process XIV. Adjournment...

A Nonparametric Approach to Segmentation of Ladar Images

DTIC Science & Technology

2012-12-01

82 5.3.4 Simulation ...91 6.2.1 Multi-Facet Board Simulation ...Pulse spreading effects are ignored. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 xiii Figure Page 5.4. Signal pulse energy with

Proceedings of the Tenth International Winterschool on New Developments in Solid State Physics "New Frontiers in Low-Dimensional Physics," Held in Mauterndorf, Austria, on 23-27 February 1998

DTIC Science & Technology

1998-02-01

Pfeiffer, K.W. West, cially pronounced for emission from the antibonding Science 264 (1994) 1740. level. This decrease of the exciton lifetime for...1996)1624. R.T Cox, A. Tardot, C. Grattepain, J. Appl. Phys. 7211(96124R.T92) Cox,; A. Tardot, C. G rattepain, J. WapD . Phy. 7 [26] R. Egger, H

Department of Transportation Agency Semiannual Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-20

... [The Regulatory Plan and Unified Agenda of Federal Regulatory and Deregulatory Actions] [Department of Transportation Agency Semiannual Regulatory Agenda ] Part XIII Department of Transportation Semiannual Regulatory Agenda [[Page 79812

32 CFR 865.114 - Decisional document.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Awards and decorations. (ix) Educational level. (x) Aptitude test scores. (xi) Incidents of punishment... punishment). (xii) Conviction by court-martial. (xiii) Prior military service and type of discharge received...

32 CFR 865.114 - Decisional document.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Awards and decorations. (ix) Educational level. (x) Aptitude test scores. (xi) Incidents of punishment... punishment). (xii) Conviction by court-martial. (xiii) Prior military service and type of discharge received...

32 CFR 865.114 - Decisional document.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Awards and decorations. (ix) Educational level. (x) Aptitude test scores. (xi) Incidents of punishment... punishment). (xii) Conviction by court-martial. (xiii) Prior military service and type of discharge received...

32 CFR 865.114 - Decisional document.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Awards and decorations. (ix) Educational level. (x) Aptitude test scores. (xi) Incidents of punishment... punishment). (xii) Conviction by court-martial. (xiii) Prior military service and type of discharge received...

77 FR 67368 - Medicare and Medicaid Programs; Quarterly Listing of Program Issuances-July through September 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-09

...) Facilities. XIII Medicare-Approved Lung JoAnna Baldwin, MS. (410) 786-7205 Volume Reduction Surgery Facilities. XIV Medicare-Approved Bariatric Kate Tillman, RN, (410) 786-9252 Surgery Facilities. MAS. XV...

49 CFR 1572.103 - Disqualifying criminal offenses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... controlled substance. (viii) Arson. (ix) Kidnapping or hostage taking. (x) Rape or aggravated sexual abuse. (xi) Assault with intent to kill. (xii) Robbery. (xiii) Fraudulent entry into a seaport as described...

49 CFR 1572.103 - Disqualifying criminal offenses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... controlled substance. (viii) Arson. (ix) Kidnapping or hostage taking. (x) Rape or aggravated sexual abuse. (xi) Assault with intent to kill. (xii) Robbery. (xiii) Fraudulent entry into a seaport as described...

8 CFR 214.4 - Denial of certification, denial of recertification or withdrawal of SEVP certification.

Code of Federal Regulations, 2011 CFR

2011-01-01

...). (xii) Failure to operate as a bona fide institution of learning. (xiii) Failure to employ adequate...) Failure to maintain the physical plant, curriculum, and teaching staff in the manner represented in the...

Local dynamics measured by hydrogen/deuterium exchange and mass spectrometry of creatine kinase digested by two proteases.

PubMed

Mazon, Hortense; Marcillat, Olivier; Forest, Eric; Vial, Christian

2005-12-01

Hydrogen/deuterium exchange coupled to mass spectrometry has been used to investigate the structure and dynamics of native dimeric cytosolic muscle creatine kinase. The protein was incubated in D2O for various time. After H/D exchange and rapid quenching of the reaction, the partially deuterated protein was cleaved in parallel by two different proteases (pepsin or type XIII protease from Aspergillus saitoi) to increase the sequence coverage and spatial resolution of deuterium incorporation. The resulting peptides were analyzed by liquid chromatography coupled to mass spectrometry. In comparison with the 3D structure of MM-CK, the analysis of the two independent proteolysis deuteration patterns allowed us to get new insights into CK local dynamics as compared to a previous study using pepsin [Mazon et al. Protein Science 13 (2004) 476-486]. In particular, we obtained more information on the kinetics and extent of deuterium exchange in the N- and C-terminal extremities represented by the 1-22 and 362-380 pepsin peptides. Indeed, we observed a very different behaviour of the 1-12 and 13-22 type XIII protease peptides, and similarly for the 362-373 and 374-380 peptides. Moreover, comparison of the deuteration patterns of type XIII protease segments of the large 90-126 pepsin peptide led us to identify a small relatively dynamic region (108-114).

Book review: Rogue waves in the ocean

USGS Publications Warehouse

Geist, Eric L.

2011-01-01

Review info: Rogue Waves in the Ocean. Advances in Geophysical and Environmental Mechanics and Mathematics. By Christian Kharif, Efim Pelinovsky and Alexey Slunyaev, 2009. ISBN: 978-3540884187, xiii, 216 pp.

Design and Analysis of an Electron Gun/Booster and Free Electron Laser Optical Theory

DTIC Science & Technology

2010-09-01

42 23. Simplified cathode assembly model . . . . . . . . . . . . . . . . . . . . 45 24. Rossendorf and BNL RF chokes...225 123. Cross-correlation maps . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 124. BNL SDL optical field...amplitude . . . . . . . . . . . . . . . . . . . . . 230 125. BNL SDL Gain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230 xiii THIS

19 CFR 122.183 - Denial of access.

Code of Federal Regulations, 2014 CFR

2014-04-01

...) Destruction of an aircraft or aircraft facility (18 U.S.C. 32); (xiii) Murder; (xiv) Assault with intent to murder; (xv) Espionage; (xvi) Sedition; (xvii) Kidnapping or hostage taking; (xviii) Treason; (xix) Rape...

19 CFR 122.183 - Denial of access.

Code of Federal Regulations, 2013 CFR

2013-04-01

...) Destruction of an aircraft or aircraft facility (18 U.S.C. 32); (xiii) Murder; (xiv) Assault with intent to murder; (xv) Espionage; (xvi) Sedition; (xvii) Kidnapping or hostage taking; (xviii) Treason; (xix) Rape...

Planck 2015 results: XIII. Cosmological parameters

DOE PAGES

Ade, P. A. R.; Aghanim, N.; Arnaud, M.; ...

2016-09-20

Here, this paper presents cosmological results based on full-mission Planck observations of temperature and polarization anisotropies of the cosmic microwave background (CMB) radiation. Our results are in very good agreement with the 2013 analysis of the Planck nominal-mission temperature data, but with increased precision. The temperature and polarization power spectra are consistent with the standard spatially-flat 6-parameter ΛCDM cosmology with a power-law spectrum of adiabatic scalar perturbations (denoted “base ΛCDM” in this paper). From the Planck temperature data combined with Planck lensing, for this cosmology we find a Hubble constant, H 0 = (67.8 ± 0.9) km s -1Mpc -1, a matter density parameter Ω m = 0.308 ± 0.012, and a tilted scalar spectral index with n s = 0.968 ± 0.006, consistent with the 2013 analysis. Note that in this abstract we quote 68% confidence limits on measured parameters and 95% upper limits on other parameters. We present the first results of polarization measurements with the Low Frequency Instrument at large angular scales. Combined with the Planck temperature and lensing data, these measurements give a reionization optical depth of τ = 0.066 ± 0.016, corresponding to a reionization redshift of z re= 8.8more » $$+1.7\\atop{-1.4}$$. These results are consistent with those from WMAP polarization measurements cleaned for dust emission using 353-GHz polarization maps from the High Frequency Instrument. We find no evidence for any departure from base ΛCDM in the neutrino sector of the theory; for example, combining Planck observations with other astrophysical data we find N eff = 3.15 ± 0.23 for the effective number of relativistic degrees of freedom, consistent with the value N eff = 3.046 of the Standard Model of particle physics. The sum of neutrino masses is constrained to Σ m ν < 0.23 eV. The spatial curvature of our Universe is found to be very close to zero, with | Ω K | < 0.005. Adding a tensor component as a single-parameter extension to base ΛCDM we find an upper limit on the tensor-to-scalar ratio of r 0.002< 0.11, consistent with the Planck 2013 results and consistent with the B-mode polarization constraints from a joint analysis of BICEP2, Keck Array, and Planck (BKP) data. Adding the BKP B-mode data to our analysis leads to a tighter constraint of r 0.002 < 0.09 and disfavours inflationarymodels with a V(φ) ∝ φ 2 potential. The addition of Planck polarization data leads to strong constraints on deviations from a purely adiabatic spectrum of fluctuations. We find no evidence for any contribution from isocurvature perturbations or from cosmic defects. Combining Planck data with other astrophysical data, including Type Ia supernovae, the equation of state of dark energy is constrained to w = -1.006 ± 0.045, consistent with the expected value for a cosmological constant. The standard big bang nucleosynthesis predictions for the helium and deuterium abundances for the best-fit Planck base ΛCDM cosmology are in excellent agreement with observations. We also constraints on annihilating dark matter and on possible deviations from the standard recombination history. In neither case do we find no evidence for new physics. The Planck results for base ΛCDM are in good agreement with baryon acoustic oscillation data and with the JLA sample of Type Ia supernovae. However, as in the 2013 analysis, the amplitude of the fluctuation spectrum is found to be higher than inferred from some analyses of rich cluster counts and weak gravitational lensing. We show that these tensions cannot easily be resolved with simple modifications of the base ΛCDM cosmology. Finally, apart from these tensions, the base ΛCDM cosmology provides an excellent description of the Planck CMB observations and many other astrophysical data sets.« less

Planck 2015 results. XIII. Cosmological parameters

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartlett, J. G.; Bartolo, N.; Battaner, E.; Battye, R.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.-R.; Chiang, H. C.; Chluba, J.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Désert, F.-X.; Di Valentino, E.; Dickinson, C.; Diego, J. M.; Dolag, K.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dunkley, J.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Farhang, M.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Gauthier, C.; Gerbino, M.; Ghosh, T.; Giard, M.; Giraud-Héraud, Y.; Giusarma, E.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J. E.; Hamann, J.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Helou, G.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huang, Z.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Lewis, A.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Marchini, A.; Maris, M.; Martin, P. G.; Martinelli, M.; Martínez-González, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Melin, J.-B.; Mendes, L.; Mennella, A.; Migliaccio, M.; Millea, M.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rouillé d'Orfeuil, B.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Said, N.; Salvatelli, V.; Salvati, L.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M. D.; Serra, P.; Shellard, E. P. S.; Spencer, L. D.; Spinelli, M.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Tucci, M.; Tuovinen, J.; Türler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, F.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Wehus, I. K.; White, M.; White, S. D. M.; Wilkinson, A.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-09-01

This paper presents cosmological results based on full-mission Planck observations of temperature and polarization anisotropies of the cosmic microwave background (CMB) radiation. Our results are in very good agreement with the 2013 analysis of the Planck nominal-mission temperature data, but with increased precision. The temperature and polarization power spectra are consistent with the standard spatially-flat 6-parameter ΛCDM cosmology with a power-law spectrum of adiabatic scalar perturbations (denoted "base ΛCDM" in this paper). From the Planck temperature data combined with Planck lensing, for this cosmology we find a Hubble constant, H0 = (67.8 ± 0.9) km s-1Mpc-1, a matter density parameter Ωm = 0.308 ± 0.012, and a tilted scalar spectral index with ns = 0.968 ± 0.006, consistent with the 2013 analysis. Note that in this abstract we quote 68% confidence limits on measured parameters and 95% upper limits on other parameters. We present the first results of polarization measurements with the Low Frequency Instrument at large angular scales. Combined with the Planck temperature and lensing data, these measurements give a reionization optical depth of τ = 0.066 ± 0.016, corresponding to a reionization redshift of z_re=8.8+1.7-1.4. These results are consistent with those from WMAP polarization measurements cleaned for dust emission using 353-GHz polarization maps from the High Frequency Instrument. We find no evidence for any departure from base ΛCDM in the neutrino sector of the theory; for example, combining Planck observations with other astrophysical data we find Neff = 3.15 ± 0.23 for the effective number of relativistic degrees of freedom, consistent with the value Neff = 3.046 of the Standard Model of particle physics. The sum of neutrino masses is constrained to ∑ mν < 0.23 eV. The spatial curvature of our Universe is found to be very close to zero, with | ΩK | < 0.005. Adding a tensor component as a single-parameter extension to base ΛCDM we find an upper limit on the tensor-to-scalar ratio of r0.002< 0.11, consistent with the Planck 2013 results and consistent with the B-mode polarization constraints from a joint analysis of BICEP2, Keck Array, and Planck (BKP) data. Adding the BKP B-mode data to our analysis leads to a tighter constraint of r0.002 < 0.09 and disfavours inflationarymodels with a V(φ) ∝ φ2 potential. The addition of Planck polarization data leads to strong constraints on deviations from a purely adiabatic spectrum of fluctuations. We find no evidence for any contribution from isocurvature perturbations or from cosmic defects. Combining Planck data with other astrophysical data, including Type Ia supernovae, the equation of state of dark energy is constrained to w = -1.006 ± 0.045, consistent with the expected value for a cosmological constant. The standard big bang nucleosynthesis predictions for the helium and deuterium abundances for the best-fit Planck base ΛCDM cosmology are in excellent agreement with observations. We also constraints on annihilating dark matter and on possible deviations from the standard recombination history. In neither case do we find no evidence for new physics. The Planck results for base ΛCDM are in good agreement with baryon acoustic oscillation data and with the JLA sample of Type Ia supernovae. However, as in the 2013 analysis, the amplitude of the fluctuation spectrum is found to be higher than inferred from some analyses of rich cluster counts and weak gravitational lensing. We show that these tensions cannot easily be resolved with simple modifications of the base ΛCDM cosmology. Apart from these tensions, the base ΛCDM cosmology provides an excellent description of the Planck CMB observations and many other astrophysical data sets.

Planck 2015 results: XIII. Cosmological parameters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ade, P. A. R.; Aghanim, N.; Arnaud, M.

Here, this paper presents cosmological results based on full-mission Planck observations of temperature and polarization anisotropies of the cosmic microwave background (CMB) radiation. Our results are in very good agreement with the 2013 analysis of the Planck nominal-mission temperature data, but with increased precision. The temperature and polarization power spectra are consistent with the standard spatially-flat 6-parameter ΛCDM cosmology with a power-law spectrum of adiabatic scalar perturbations (denoted “base ΛCDM” in this paper). From the Planck temperature data combined with Planck lensing, for this cosmology we find a Hubble constant, H 0 = (67.8 ± 0.9) km s -1Mpc -1, a matter density parameter Ω m = 0.308 ± 0.012, and a tilted scalar spectral index with n s = 0.968 ± 0.006, consistent with the 2013 analysis. Note that in this abstract we quote 68% confidence limits on measured parameters and 95% upper limits on other parameters. We present the first results of polarization measurements with the Low Frequency Instrument at large angular scales. Combined with the Planck temperature and lensing data, these measurements give a reionization optical depth of τ = 0.066 ± 0.016, corresponding to a reionization redshift of z re= 8.8more » $$+1.7\\atop{-1.4}$$. These results are consistent with those from WMAP polarization measurements cleaned for dust emission using 353-GHz polarization maps from the High Frequency Instrument. We find no evidence for any departure from base ΛCDM in the neutrino sector of the theory; for example, combining Planck observations with other astrophysical data we find N eff = 3.15 ± 0.23 for the effective number of relativistic degrees of freedom, consistent with the value N eff = 3.046 of the Standard Model of particle physics. The sum of neutrino masses is constrained to Σ m ν < 0.23 eV. The spatial curvature of our Universe is found to be very close to zero, with | Ω K | < 0.005. Adding a tensor component as a single-parameter extension to base ΛCDM we find an upper limit on the tensor-to-scalar ratio of r 0.002< 0.11, consistent with the Planck 2013 results and consistent with the B-mode polarization constraints from a joint analysis of BICEP2, Keck Array, and Planck (BKP) data. Adding the BKP B-mode data to our analysis leads to a tighter constraint of r 0.002 < 0.09 and disfavours inflationarymodels with a V(φ) ∝ φ 2 potential. The addition of Planck polarization data leads to strong constraints on deviations from a purely adiabatic spectrum of fluctuations. We find no evidence for any contribution from isocurvature perturbations or from cosmic defects. Combining Planck data with other astrophysical data, including Type Ia supernovae, the equation of state of dark energy is constrained to w = -1.006 ± 0.045, consistent with the expected value for a cosmological constant. The standard big bang nucleosynthesis predictions for the helium and deuterium abundances for the best-fit Planck base ΛCDM cosmology are in excellent agreement with observations. We also constraints on annihilating dark matter and on possible deviations from the standard recombination history. In neither case do we find no evidence for new physics. The Planck results for base ΛCDM are in good agreement with baryon acoustic oscillation data and with the JLA sample of Type Ia supernovae. However, as in the 2013 analysis, the amplitude of the fluctuation spectrum is found to be higher than inferred from some analyses of rich cluster counts and weak gravitational lensing. We show that these tensions cannot easily be resolved with simple modifications of the base ΛCDM cosmology. Finally, apart from these tensions, the base ΛCDM cosmology provides an excellent description of the Planck CMB observations and many other astrophysical data sets.« less

Identifying and Analyzing Federal Government Market Opportunities for OpalSoft

DTIC Science & Technology

2004-09-01

OPPORTUNITIES, AND THREATS ( SWOT ) ANALYSIS......................................................................................13 1. Strengths...xiii LIST OF TABLES Table 1. SWOT Analysis...of industries to include Fortune 500 companies. Current key clients are Amkor, Symantec, Unisys Corporation, Apple Computers, Palm, Inc., and

Quantifying Nanoparticle Internalization Using a High Throughput Internalization Assay.

PubMed

Mann, Sarah K; Czuba, Ewa; Selby, Laura I; Such, Georgina K; Johnston, Angus P R

2016-10-01

The internalization of nanoparticles into cells is critical for effective nanoparticle mediated drug delivery. To investigate the kinetics and mechanism of internalization of nanoparticles into cells we have developed a DNA molecular sensor, termed the Specific Hybridization Internalization Probe - SHIP. Self-assembling polymeric 'pHlexi' nanoparticles were functionalized with a Fluorescent Internalization Probe (FIP) and the interactions with two different cell lines (3T3 and CEM cells) were studied. The kinetics of internalization were quantified and chemical inhibitors that inhibited energy dependent endocytosis (sodium azide), dynamin dependent endocytosis (Dyngo-4a) and macropinocytosis (5-(N-ethyl-N-isopropyl) amiloride (EIPA)) were used to study the mechanism of internalization. Nanoparticle internalization kinetics were significantly faster in 3T3 cells than CEM cells. We have shown that ~90% of the nanoparticles associated with 3T3 cells were internalized, compared to only 20% of the nanoparticles associated with CEM cells. Nanoparticle uptake was via a dynamin-dependent pathway, and the nanoparticles were trafficked to lysosomal compartments once internalized. SHIP is able to distinguish between nanoparticles that are associated on the outer cell membrane from nanoparticles that are internalized. This study demonstrates the assay can be used to probe the kinetics of nanoparticle internalization and the mechanisms by which the nanoparticles are taken up by cells. This information is fundamental for engineering more effective nanoparticle delivery systems. The SHIP assay is a simple and a high-throughput technique that could have wide application in therapeutic delivery research.

Highway Safety Information System guidebook for the Maine state data files. Volume 1 : SAS file formats

DOT National Transportation Integrated Search

2012-05-05

As part of the Federal Highway Administration (FHWA) Traffic Analysis Toolbox (Volume XIII), this guide was designed to help corridor stakeholders implement the ICM AMS methodology successfully and effectively. It provides a step-by-step approach to ...

16 CFR 4.9 - The public record.

Code of Federal Regulations, 2010 CFR

2010-01-01

... to § 305.8 of this chapter; (xiii) Annual filings by professional boxing sanctioning organizations as required by the Muhammed Ali Boxing Reform Act, 15 U.S.C. 6301 note, 6307a-6307h; (xiv) Other documents...

Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides.

PubMed

Supuran, Claudiu T

2008-01-01

The widely clinically used benzothiadiazines and high ceiling diuretics, such as hydrochlorothiazide, hydroflumethiazide, quinethazone, metolazone, chlorthalidone, indapamide, furosemide and bumetanide, contain SO(2)NH(2) moieties acting as an effective zinc-binding function in carbonic anhydrases (CAs, EC 4.2.1.1) inhibitors. These drugs were launched in a period when only isoform CA II was known and considered physiologically/pharmacologically relevant. Although acting as moderate-weak inhibitors of CA II, all these drugs considerably inhibit other CA isozymes known nowadays to be involved in critical physiologic processes, among the 16 CAs present in vertebrates. Some low nanomolar (or even subnanomolar) inhibitors against such isoforms were recently detected, such as metholazone against CA VII, XII and XIII, chlorthalidone against CA VB, VII, IX, XII and XIII, indapamide against CA VII, IX, XII and XIII, furosemide against CA I, II and XIV, and bumethanide against CA IX and XII. The X-ray crystal structure of the CA II-indapamide adduct was also reported recently, revealing interesting aspects useful for the drug design of CA inhibitors. It has also been proposed that the recently observed beneficial effect of indapamide for the treatment of patients with hypertension and type 2 diabetes might be due to its potent inhibition of CA isoforms present in kidneys and blood vessels, which would thus explain both the blood pressure lowering effects as well as organ-protective activity of the drug. Thus, these old drugs may be useful as leads for new applications.

38 CFR 3.815 - Monetary allowance under 38 U.S.C. chapter 18 for an individual with disability from covered...

Code of Federal Regulations, 2012 CFR

2012-07-01

..., the following: (i) Down syndrome and other Trisomies; (ii) Fragile X syndrome; (iii) Klinefelter's... atresia; (vi) Hallerman-Streiff syndrome; (vii) Hip dysplasia; (viii) Hirschprung's disease (congenital...) Neural tube defects (including spina bifida, encephalocele, and anencephaly); (xiii) Poland syndrome...

38 CFR 3.815 - Monetary allowance under 38 U.S.C. chapter 18 for an individual with disability from covered...

Code of Federal Regulations, 2013 CFR

2013-07-01

..., the following: (i) Down syndrome and other Trisomies; (ii) Fragile X syndrome; (iii) Klinefelter's... atresia; (vi) Hallerman-Streiff syndrome; (vii) Hip dysplasia; (viii) Hirschprung's disease (congenital...) Neural tube defects (including spina bifida, encephalocele, and anencephaly); (xiii) Poland syndrome...

38 CFR 3.815 - Monetary allowance under 38 U.S.C. chapter 18 for an individual with disability from covered...

Code of Federal Regulations, 2014 CFR

2014-07-01

..., the following: (i) Down syndrome and other Trisomies; (ii) Fragile X syndrome; (iii) Klinefelter's... atresia; (vi) Hallerman-Streiff syndrome; (vii) Hip dysplasia; (viii) Hirschprung's disease (congenital...) Neural tube defects (including spina bifida, encephalocele, and anencephaly); (xiii) Poland syndrome...

Continental Drift: International Students Become International Alumni and Create International Institutions

ERIC Educational Resources Information Center

Pulley, John

2009-01-01

No nation would entrust its foreign relations to ambassadors bereft of international experience. Nor would a global conglomerate ignore overseas markets and expect to prosper. Yet colleges and universities have frequently taken a remarkably unsophisticated and laissez faire approach to advancing their international interests--if they have bothered…

26 CFR 1.897-5T - Corporate distributions (temporary).

Code of Federal Regulations, 2014 CFR

2014-04-01

... provided in section 897 and the regulations thereunder, except as provided by Articles XIII (9) and XXX (5... June 6, 1988. With regard to Article XXX (5) of the Income Tax Treaty with Canada, see, Rev. Rul. 85-76...

26 CFR 1.897-5T - Corporate distributions (temporary).

Code of Federal Regulations, 2011 CFR

2011-04-01

... provided in section 897 and the regulations thereunder, except as provided by Articles XIII (9) and XXX (5... June 6, 1988. With regard to Article XXX (5) of the Income Tax Treaty with Canada, see, Rev. Rul. 85-76...

26 CFR 1.897-5T - Corporate distributions (temporary).

Code of Federal Regulations, 2012 CFR

2012-04-01

... provided in section 897 and the regulations thereunder, except as provided by Articles XIII (9) and XXX (5... June 6, 1988. With regard to Article XXX (5) of the Income Tax Treaty with Canada, see, Rev. Rul. 85-76...

26 CFR 1.897-5T - Corporate distributions (temporary).

Code of Federal Regulations, 2013 CFR

2013-04-01

... provided in section 897 and the regulations thereunder, except as provided by Articles XIII (9) and XXX (5... June 6, 1988. With regard to Article XXX (5) of the Income Tax Treaty with Canada, see, Rev. Rul. 85-76...

26 CFR 1.897-5T - Corporate distributions (temporary).

Code of Federal Regulations, 2010 CFR

2010-04-01

... provided in section 897 and the regulations thereunder, except as provided by Articles XIII (9) and XXX (5... June 6, 1988. With regard to Article XXX (5) of the Income Tax Treaty with Canada, see, Rev. Rul. 85-76...

78 FR 16302 - Sunshine Act Meeting; Regular Board of Directors Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-14

..., Washington, DC 20005. STATUS: Open. CONTACT PERSON FOR MORE INFORMATION: Erica Hall, Assistant Corporate... Discussion IV. Financial Report V. DC Office Move VI. NCST Board VII. Homeownership Challenges..., NFMC & EHLP Reports XII. Executive Session XIII. Adjournment Erica Hall, Assistant Corporate Secretary...

45 CFR 307.11 - Functional requirements for computerized support enforcement systems in operation by October 1...

Code of Federal Regulations, 2011 CFR

2011-10-01

... violence or child abuse); (xi) Indication of an order; (xii) Locate request type (optional); (xiii) Locate... to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT...

45 CFR 307.11 - Functional requirements for computerized support enforcement systems in operation by October 1...

Code of Federal Regulations, 2013 CFR

2013-10-01

... violence or child abuse); (xi) Indication of an order; (xii) Locate request type (optional); (xiii) Locate... to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT...

45 CFR 307.11 - Functional requirements for computerized support enforcement systems in operation by October 1...

Code of Federal Regulations, 2012 CFR

2012-10-01

... violence or child abuse); (xi) Indication of an order; (xii) Locate request type (optional); (xiii) Locate... to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT...

76 FR 17870 - Medicare and Medicaid Programs; Quarterly Listing of Program Issuances-October Through December 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... Registry (NOPR) Sites. Addendum XIII: Medicare-approved Ventricular Assist Device (Destination Therapy... Therapy) Facilities (October Through December 2010) On October 1, 2003, we issued our decision memorandum on ventricular assist devices (VADs) for the clinical indication of destination therapy. We...

33 CFR 385.26 - Project Implementation Reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Implementation Report is a document that provides information on plan formulation and evaluation, engineering and..., environmental and/or economic benefits, engineering and design, costs, environmental impacts, real estate..., optimization and justification, cost-effectiveness, and engineering feasibility of the project; (xiii) Include...

75 FR 42000 - Requirements for Fingerprint-Based Criminal History Records Checks for Individuals Seeking...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-20

... Compatibility VIII. Plain Language IX. Voluntary Consensus Standards X. Finding of No Significant Environmental Impact: Availability XI. Paperwork Reduction Act Statement XII. Regulatory Analysis: Availability XIII... received seven comment letters from interested parties: Four from RTR licensees, one from the Nuclear...

Defining International Education.

ERIC Educational Resources Information Center

Hansen, Holly Moran

2002-01-01

Discusses the three facets of international education: international studies, international education exchange, and technical assistance. Also explores the effects of internationalizing higher education and the present state of international education. (EV)

Internation Cooperation.

ERIC Educational Resources Information Center

Scheeder, Donna; And Others

1990-01-01

Special libraries abroad and international cooperative efforts are discussed in six articles. Topics covered include the international role of the Special Libraries Association; the Special Library Program of the U.S. Information Agency; the design of special libraries abroad; regional networks that cross international boundaries; and the…

77 FR 29564 - Revisions to the Export Administration Regulations: Auxiliary and Miscellaneous Items That No...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-18

...The Bureau of Industry and Security (BIS) publishes this action to propose how auxiliary and miscellaneous military equipment and related articles the President determines no longer warrant control under Category XIII (Auxiliary Military Equipment) of the United States Munitions List (USML) would be controlled under the Commerce Control List (CCL) in new Export Control Classification Numbers (ECCNs) 0A617, 0B617, 0C617, 0D617, and 0E617 as part of the proposed new ``600 series'' of ECCNs. This rule proposes also to integrate into those five new ECCNs items within the scope of Wassenaar Arrangement Munitions List (WAML) Category 17 that would be removed from the USML, or that are not specifically identified on the USML or CCL but that are currently subject to USML jurisdiction. Finally, this rule proposes to control some items now classified under ECCNs 0A018, 0A918 and 0E018 under new ECCNs 0A617 and 0E617. This action would consolidate the above- mentioned auxiliary and miscellaneous military equipment and related articles on the CCL in the proposed new ``600 series.'' This rule is one of a planned series proposing how various types of articles that the President determines, as part of the Administration's Export Control Reform Initiative, no longer warrant control on the USML under the International Traffic in Arms Regulations (ITAR), would be controlled on the CCL in accordance with the requirements of the Export Administration Regulations (EAR). This proposed rule is being published in conjunction with a proposed rule from the Department of State, Directorate of Defense Trade Controls, which would amend the list of articles controlled by USML Category XIII.

Evaluation of Factor V G1691A, prothrombin G20210A, Factor XIII V34L, MTHFR A1298C, MTHFR C677T and PAI-1 4G/5G genotype frequencies of patients subjected to cardiovascular disease (CVD) panel in south-east region of Turkey.

PubMed

Oztuzcu, Serdar; Ergun, Sercan; Ulaşlı, Mustafa; Nacarkahya, Gülper; Iğci, Yusuf Ziya; Iğci, Mehri; Bayraktar, Recep; Tamer, Ali; Çakmak, Ecir Ali; Arslan, Ahmet

2014-06-01

Cardiovascular disease (CVD) risk factors, such as arterial hypertension, obesity, dyslipidemia or diabetes mellitus, as well as CVDs, including myocardial infarction, coronary artery disease or stroke, are the most prevalent diseases and account for the major causes of death worldwide. In the present study, 4,709 unrelated patients subjected to CVD panel in south-east part of Turkey between the years 2010 and 2013 were enrolled and DNA was isolated from the blood samples of these patients. Mutation analyses were conducted using the real-time polymerase chain reaction method to screen six common mutations (Factor V G1691A, PT G20210A, Factor XIII V34L, MTHFR A1298C and C677T and PAI-1 -675 4G/5G) found in CVD panel. The prevalence of these mutations were 0.57, 0.25, 2.61, 13.78, 9.34 and 24.27 % in homozygous form, respectively. Similarly, the mutation percent of them in heterozygous form were 7.43, 3.44, 24.91, 44.94, 41.09 and 45.66%, respectively. No mutation was detected in 92 (1.95%) patients in total. Because of the fact that this is the first study to screen six common mutations in CVD panel in south-east region of Turkey, it has a considerable value on the diagnosis and treatment of these diseases. Upon the results of the present and previous studied a careful examination for these genetic variants should be carried out in thrombophilia screening programs, particularly in Turkish population.

40 CFR 60.53c - Operator training and qualification requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... and types of emissions; (ii) Basic combustion principles, including products of combustion; (iii) Operation of the type of incinerator to be used by the operator, including proper startup, waste charging... procedures; (xii) Pre-startup inspections; and (xiii) Recordkeeping requirements. (2) An examination designed...

40 CFR 60.53c - Operator training and qualification requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... and types of emissions; (ii) Basic combustion principles, including products of combustion; (iii) Operation of the type of incinerator to be used by the operator, including proper startup, waste charging... procedures; (xii) Pre-startup inspections; and (xiii) Recordkeeping requirements. (2) An examination designed...

The Business Case for Systems Engineering Study: Detailed Response Data

DTIC Science & Technology

2012-11-01

of Carnegie Mellon University. DM -0000794 CMU/SEI-2012-SR-011 | i Table of Contents Acknowledgments ix Executive Summary xi Abstract xiii...providing an SRD25 upfront with crisp requirements. Customer/acquirer consistently talks about SE but never practices SE. Customer practices SE

24 CFR 576.400 - Area-wide systems coordination requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

...): (8) Head Start (45 CFR chapter XIII, subchapter B); (9) Mental Health and Substance Abuse Block..., if any, on the homelessness prevention or rapid re-housing assistance that each program participant... HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES EMERGENCY SOLUTIONS GRANTS PROGRAM Program Requirements...

24 CFR 576.400 - Area-wide systems coordination requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

...): (8) Head Start (45 CFR chapter XIII, subchapter B); (9) Mental Health and Substance Abuse Block..., if any, on the homelessness prevention or rapid re-housing assistance that each program participant... HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES EMERGENCY SOLUTIONS GRANTS PROGRAM Program Requirements...

24 CFR 576.400 - Area-wide systems coordination requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

...): (8) Head Start (45 CFR chapter XIII, subchapter B); (9) Mental Health and Substance Abuse Block..., if any, on the homelessness prevention or rapid re-housing assistance that each program participant... HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES EMERGENCY SOLUTIONS GRANTS PROGRAM Program Requirements...

42 CFR 441.464 - State assurances.

Code of Federal Regulations, 2014 CFR

2014-10-01

... services, supports, and resources. (xii) Development of risk management agreements. (xiii) Development of... Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... protect the health and welfare of individuals furnished services under the program and to assure the...

42 CFR 441.464 - State assurances.

Code of Federal Regulations, 2012 CFR

2012-10-01

... services, supports, and resources. (xii) Development of risk management agreements. (xiii) Development of... Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... protect the health and welfare of individuals furnished services under the program and to assure the...

42 CFR 441.464 - State assurances.

Code of Federal Regulations, 2013 CFR

2013-10-01

... services, supports, and resources. (xii) Development of risk management agreements. (xiii) Development of... Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... protect the health and welfare of individuals furnished services under the program and to assure the...

75 FR 55274 - Change of Address for Region 5 State and Local Agencies; Technical Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-10

... Health District, Air Pollution Control, 33 Mill Street, Painesville, OH 44077. (xiv) Mahoning and...; Director, Canton City Health Department, Air Pollution Control Division, 420 Market Avenue North, Canton.... (xiii) Geauga and Lake Counties; Lake County General Health District, Air Pollution Control, 33 Mill...

40 CFR 62.14595 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... charging, and shutdown procedures. (iv) Combustion controls and monitoring. (v) Operation of air pollution... the incinerator and air pollution control devices. (vii) Actions to correct malfunctions or conditions... requirements. (xiii) Methods to continuously monitor CISWI unit and air pollution control device operating...

40 CFR 62.14595 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2011 CFR

2011-07-01

... charging, and shutdown procedures. (iv) Combustion controls and monitoring. (v) Operation of air pollution... the incinerator and air pollution control devices. (vii) Actions to correct malfunctions or conditions... requirements. (xiii) Methods to continuously monitor CISWI unit and air pollution control device operating...

76 FR 6199 - Enhanced Weapons, Firearms Background Checks, and Security Event Notifications

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-03

... XI. Voluntary Consensus Standards XII. Finding of No Significant Environmental Impact XIII. Paperwork... potential advantages to NRC licensees and certificate holders to enhance security. The first advantage is... advantage is that security personnel of certain licensees or certificate holders will be permitted to...

The Mississippi River Campaign 1862-1863: The Impact of Climate and Pathogens on Operational Art at the Port Hudson Siege

DTIC Science & Technology

2017-04-13

48 1 Introduction Sun Tzu , for one, advised commanders to, “camp on hard ground, the army...51 Bibliography ...Society Papers Volume XIII January to December 1885 (Richmond, VA: The Society, 1891), 329; Bell, 31. 248 Bell, 30. 52 Bibliography Army Doctrine

7. Photocopied December 1977, form F.B. Tower, Illustrations of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Photocopied December 1977, form F.B. Tower, Illustrations of the Croton Aqueduct, New York: Wiley and Putnam, 1843. CROTON AQUEDUCT AT SING SING, PLATE XIII, PAGE 101. - Old Croton Aqueduct, Sing Sing Kill Bridge, Spanning Aqueduct Street & Broadway, Ossining, Westchester County, NY

Sylphellapuccoon gen. n., sp. n. and two additional new species of aquatic oligochaetes (Lumbriculidae, Clitellata) from poorly-known lotic habitats in North Carolina (USA).

PubMed

Rodriguez, Pilar; Fend, Steven V; Lenat, David R

2014-01-01

Three new species of Lumbriculidae were collected from floodplain seeps and small streams in southeastern North America. Some of these habitats are naturally acidic. Sylphellapuccoon gen. n., sp. n. has prosoporous male ducts in X-XI, and spermathecae in XII-XIII. Muscular, spherical atrial ampullae and acuminate penial sheaths distinguish this monotypic new genus from other lumbriculid genera having similar arrangements of reproductive organs. Cookidriluspocosinus sp. n. resembles its two subterranean, Palearctic congeners in the arrangement of reproductive organs, but is easily distinguished by the position of the spermathecal pores in front of the chaetae in X-XIII. Stylodriluscoreyi sp. n. differs from congeners having simple-pointed chaetae and elongate atria primarily by the structure of the male duct and the large clusters of prostate cells. Streams and wetlands of Southeastern USA have a remarkably high diversity of endemic lumbriculids, and these poorly-known invertebrates should be considered in conservation efforts.

Diagnosing the Magnetic Field Structure of a Coronal Cavity Observed during the 2017 Total Solar Eclipse

NASA Astrophysics Data System (ADS)

Chen, Yajie; Tian, Hui; Su, Yingna; Qu, Zhongquan; Deng, Linhua; Jibben, Patricia R.; Yang, Zihao; Zhang, Jingwen; Samanta, Tanmoy; He, Jiansen; Wang, Linghua; Zhu, Yingjie; Zhong, Yue; Liang, Yu

2018-03-01

We present an investigation of a coronal cavity observed above the western limb in the coronal red line Fe X 6374 Å using a telescope of Peking University and in the green line Fe XIV 5303 Å using a telescope of Yunnan Observatories, Chinese Academy of Sciences, during the total solar eclipse on 2017 August 21. A series of magnetic field models is constructed based on the magnetograms taken by the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory (SDO) one week before the eclipse. The model field lines are then compared with coronal structures seen in images taken by the Atmospheric Imaging Assembly on board SDO and in our coronal red line images. The best-fit model consists of a flux rope with a twist angle of 3.1π, which is consistent with the most probable value of the total twist angle of interplanetary flux ropes observed at 1 au. Linear polarization of the Fe XIII 10747 Å line calculated from this model shows a “lagomorphic” signature that is also observed by the Coronal Multichannel Polarimeter of the High Altitude Observatory. We also find a ring-shaped structure in the line-of-sight velocity of Fe XIII 10747 Å, which implies hot plasma flows along a helical magnetic field structure, in the cavity. These results suggest that the magnetic structure of the cavity is a highly twisted flux rope, which may erupt eventually. The temperature structure of the cavity has also been investigated using the intensity ratio of Fe XIII 10747 Å and Fe X 6374 Å.

THERMAL STRUCTURE OF CORONAL LOOPS AS SEEN WITH NORIKURA CORONAGRAPH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prasad, S. Krishna; Singh, Jagdev; Ichimoto, K., E-mail: krishna@iiap.res.in

2013-03-10

The thermal structure of a coronal loop, both along and across the loop, is vital in determining the exact plasma heating mechanism. High-resolution spectroscopic observations of the off-limb corona were made using the 25 cm Norikura coronagraph, located at Norikura, Japan. Observations on a number of days were made simultaneously in four forbidden iron emission lines, namely, the [Fe XI] 7892 A line, the [Fe XIII] 10747 A and 10798 A lines, and the [Fe XIV] 5303 A line and on some days made only in the [Fe XI] 7892 A and [Fe X] 6374 A lines. Using temperature sensitivemore » emission line ratios [Fe XIV] 5303 A/[Fe XIII] 10747 A and [Fe XI] 7892 A/[Fe X] 6374 A, we compute the electron temperatures along 18 different loop structures observed on different days. We find a significant negative temperature gradient in all of the structures observed in Fe XIV and Fe XIII and a positive temperature gradient in the structures observed in Fe XI and Fe X. Combining these results with the previous investigations by Singh and his collaborators, we infer that the loop tops, in general, appear hotter when observed in colder lines and colder when observed in relatively hotter lines as compared to their coronal foot points. We suggest that this contrasting trend observed in the temperature variation along the loop structures can be explained by a gradual interaction of different temperature plasma. The exact mechanism responsible for this interaction must be investigated further and has the potential to constrain loop heating models.« less

INTERNATIONAL REPORTS: New International Standards for Quantities and Units

NASA Astrophysics Data System (ADS)

Thor, A. J.

1994-01-01

Each coherent system of units is based on a system of quantities in such a way that the equations between the numerical values expressed in coherent units have exactly the same form, including numerical factors, as the corresponding equations between the quantities. The highest international body responsible for the International System of Units (SI) is the Conférence Générale des Poids et Mesures (CGPM). However, the CGPM is not concerned with quantities or systems of quantities. That question lies within the scope of Technical Committee number twelve of the International Organization for Standardization (ISO/TC 12). Quantities, units, symbols, conversion factors. To fulfil its responsibility, ISO/TC 12 has prepared the International Standard ISO 31, Quantities and Units, which consists of fourteen parts. The new editions of the different parts of the International Standard are briefly presented here.

40 CFR 70.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

...: (i) Coal cleaning plants (with thermal dryers); (ii) Kraft pulp mills; (iii) Portland cement plants... plants; (xii) Phosphate rock processing plants; (xiii) Coke oven batteries; (xiv) Sulfur recovery plants...) totaling more than 250 million British thermal units per hour heat input; (xxii) Petroleum storage and...

40 CFR 71.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

...: (i) Coal cleaning plants (with thermal dryers); (ii) Kraft pulp mills; (iii) Portland cement plants... plants; (xii) Phosphate rock processing plants; (xiii) Coke oven batteries; (xiv) Sulfur recovery plants...) totaling more than 250 million British thermal units per hour heat input; (xxii) Petroleum storage and...

Ferrite Loaded Coils for Improved Wireless Power Transfer Efficiency

DTIC Science & Technology

2015-09-01

visible in yellow, from [4]. ..........................................................................................4  Figure 4.  The Odyssey AUV ...47  Figure 35.  System mockup of AUV in docking/charging station...42  xii THIS PAGE INTENTIONALLY LEFT BLANK xiii LIST OF ACRONYMS AND ABBREVIATIONS AUV Autonomous Underwater Vehicle CST

42 CFR 88.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... sites in the respiratory system and intrathoracic organs. (xi) Mesothelioma. (xii) Malignant neoplasms of the peripheral nerves and autonomic nervous system, and other connective and soft tissue. (xiii... disorder means a chronic or recurrent disorder of the musculoskeletal system caused by heavy lifting or...

Distance Learning Plan for the Defense Finance and Accounting Service (DFAS): A Study for the DBMU

DTIC Science & Technology

1994-09-01

according to the standard (H.261) motion video compression algorithm.24 n Schaphorst, Richard, notes presented at TELECON XIII, San Jose , California, 10...include automatic microphone mixing systems with one microphone for every two student seats, a large screen interactive computer display and the Socrates

15 CFR 30.3 - Electronic Export Information filer requirements, parties to export transactions, and...

Code of Federal Regulations, 2013 CFR

2013-01-01

.../units of measure. (ix) Value. (x) Export Control Classification Number (ECCN) or sufficient technical information to determine the ECCN. (xi) All licensing information necessary to file the EEI for commodities... export. (xi) Foreign port of unloading. (xii) Shipping weight. (xiii) ECCN. (xiv) License or license...

15 CFR 30.3 - Electronic Export Information filer requirements, parties to export transactions, and...

Code of Federal Regulations, 2010 CFR

2010-01-01

.../units of measure. (ix) Value. (x) Export Control Classification Number (ECCN) or sufficient technical information to determine the ECCN. (xi) All licensing information necessary to file the EEI for commodities... export. (xi) Foreign port of unloading. (xii) Shipping weight. (xiii) ECCN. (xiv) License or license...

15 CFR 30.3 - Electronic Export Information filer requirements, parties to export transactions, and...

Code of Federal Regulations, 2012 CFR

2012-01-01

.../units of measure. (ix) Value. (x) Export Control Classification Number (ECCN) or sufficient technical information to determine the ECCN. (xi) All licensing information necessary to file the EEI for commodities... export. (xi) Foreign port of unloading. (xii) Shipping weight. (xiii) ECCN. (xiv) License or license...

15 CFR 30.3 - Electronic Export Information filer requirements, parties to export transactions, and...

Code of Federal Regulations, 2014 CFR

2014-01-01

.../units of measure. (ix) Value. (x) Export Control Classification Number (ECCN) or sufficient technical information to determine the ECCN. (xi) All licensing information necessary to file the EEI for commodities... export. (xi) Foreign port of unloading. (xii) Shipping weight. (xiii) ECCN. (xiv) License or license...

15 CFR 30.3 - Electronic Export Information filer requirements, parties to export transactions, and...

Code of Federal Regulations, 2011 CFR

2011-01-01

.../units of measure. (ix) Value. (x) Export Control Classification Number (ECCN) or sufficient technical information to determine the ECCN. (xi) All licensing information necessary to file the EEI for commodities... export. (xi) Foreign port of unloading. (xii) Shipping weight. (xiii) ECCN. (xiv) License or license...

32 CFR 505.7 - Disclosure of personal information to other agencies and third parties.

Code of Federal Regulations, 2010 CFR

2010-07-01

... for federal employment); (xii) Social Security Number (SSN); and (xiii) The information that would... released if their positions or duties require frequent interaction with the public. (3) Disclosure of.... (g) Social rosters. (1) Before including personal information such as a spouse's name, home addresses...

Technical Modification Within the Healthcare Industry: Improving Both the Efficacy of the National Drug Code Carrier and the Accessibility of Electronic Health Records to Reduce Adverse Drug Events

DTIC Science & Technology

2013-06-01

with an EHR .................................................. 97 C. SWOT ANALYSIS OF USING QR CODES WITH THE NDC AND WITH EHRS...96 Figure 41. SWOT analysis ................................................................................... 99 xiii LIST OF...Coordinator for Health Information Technology OTC Over-the-Counter PHI Personal Health Information QR Quick Response SWOT Strengths, Weaknesses

Emergence of new sub-genotypes of virulent Newcastle disease virus with panzootic features

USDA-ARS?s Scientific Manuscript database

Newcastle disease virus (NDV) strains with epizootic characteristics from three new sub-genotypes of genotypes VII and XIII are rapidly spreading through Asia and the Middle East causing outbreaks of Newcastle disease (ND) that are producing significant illness and mortality in vaccinated poultry, s...

Surgical intern survival skills curriculum as an intern: does it help?

PubMed

Todd, S Rob; Fahy, Bridget N; Paukert, Judy; Johnson, Melanie L; Bass, Barbara L

2011-12-01

The transition from medical student to surgical intern is fraught with anxiety. We implemented a surgical intern survival skills curriculum to alleviate this through a series of lectures and interactive sessions. The purpose of this pilot study was to evaluate its effectiveness. This was a prospective observational pilot study of our surgical intern survival skills curriculum, the components of which included professionalism, medical documentation, pharmacy highlights, radiographic interpretations, nutrition, and mock clinical pages. The participants completed pre-course and post-course surveys to assess their confidence levels in the elements addressed using a 5-point Likert scale (1 = unsatisfactory, 5 = excellent). A P value of less than .05 was considered significant. In 2009, 8 interns participated in the surgical intern survival skills curriculum. Fifty percent were female and their mean age was 27.5 ± 1.5 years. Of 33 elements assessed, interns rated themselves as more confident in 27 upon completion of the course. The implementation of a surgical intern survival skills curriculum significantly improved the confidence levels of general surgery interns and seemed to ease the transition from medical student to surgical intern. Copyright © 2011 Elsevier Inc. All rights reserved.

International Heliophysical Year

NASA Technical Reports Server (NTRS)

Davila, J. M.; Harrison, R.; Poland, A.; St.Cyr, O. C.; Thompson, B. J.; Rabin, Douglas (Technical Monitor)

2002-01-01

In 1957 a program of international research, inspired by the International Polar Years of 1882-83 and 1932-33, was organized as the International Geophysical Year (IGY) to study global phenomena of the Earth and geospace. The IGY involved about 60,000 scientists from 66 nations, working at thousands of stations, from pole to pole to obtain simultaneous, global observations on Earth and in space. There had never been anything like it before. The fiftieth anniversary of the International Geophysical Year will occur in 2007. We propose to organize an international program of scientific collaboration for this time period called the International Heliophysical Year (IHY). Like it predecessors, the IHY will focus on fundamental global questions of Earth science.

Challenges and Pitfalls Facing International Education in a Post-International World

ERIC Educational Resources Information Center

Tate, Nicholas

2012-01-01

Taking as its starting point that the adjective international is an inadequate, but unavoidable, label to describe the content of a contemporary international education, this article sets out to explore some of the issues facing international education in a post-international world. It draws mainly on writings in French as a deliberate…

The International School Industry: Examining International Schools through an Economic Lens

ERIC Educational Resources Information Center

MacDonald, James

2006-01-01

Based upon the results of a quantitative analysis of tuition revenues generated by international schools, it is argued that international schools can be examined in terms of a global multi-billion dollar industry and that business theory can be, and is being, applied in international schools today. This article proposes that international schools…

International Engagement Strategy

DTIC Science & Technology

2017-06-14

agreements and issue legal guidance on international law and intellectual property issues. ICPO will play an important role in realizing this vision and...through international cooperation under the auspices of its formal international agreements with partner states and the European Commission, as well...International Engagement Opportunities for Homeland Security Research 11 S&T maintains formal bilateral agreements that provide a framework for cooperative

Waves: Internal Tides

NASA Technical Reports Server (NTRS)

Ray, Richard D.

1999-01-01

Oceanic internal tides are internal waves with tidal periodicities. They are ubiquitous throughout the ocean, although generally more pronounced near large bathymetric features such as mid-ocean ridges and continental slopes. The internal vertical displacements associated with these waves can be extraordinarily large. Near some shelf breaks where the surface tides are strong, internal displacements (e.g., of an isothermal surface) can exceed 200 meters. Displacements of 10 meters in the open ocean are not uncommon. The associated current velocities are usually comparable to or larger than the currents of the surface tide. On continental shelves internal tides can occasionally generate packets of internal solitons, which are detectable in remote sensing imagery. Other common nonlinear features are generation of higher harmonics (e.g., 6-hr waves) and wave breaking. Internal tides are known to be an important energy source for mixing of shelf waters. Recent research suggests that they may also be a significant energy source for deep-ocean mixing.

LAUNCH - APOLLO XIII - LUNAR LANDING MISSION - KSC

NASA Image and Video Library

1970-04-11

S70-34855 (11 April 1970) --- The Apollo 13 (Spacecraft 109/Lunar Module 7/Saturn 508) space vehicle is launched from Pad A, Launch Complex 39, Kennedy Space Center (KSC), at 2:13 p.m. (EST), April 11, 1970. The crew of the National Aeronautics and Space Administration's (NASA) third lunar landing mission are astronauts James A., Lovell Jr., commander; John L. Swigert Jr., command module pilot; and Fred W. Haise Jr., lunar module pilot.

XIII Modave Summer School in Mathematical Physics

NASA Astrophysics Data System (ADS)

2017-09-01

The Modave Summer School on Mathematical Physics is a yearly summer school in topics of theoretical physics. Various topics ranging from quantum gravity and cosmology to theoretical particle physics and string theory. The school takes place in Modave, a charming village in the Belgian Ardennes close to Huy. Modave School is organised by PhD students for PhD students, and this makes it rather unique. The courses are taught by Post-Docs or late PhD students, and they are all made of pedagogical, basic blackboard lectures about recent topics in theoretical physics. Participants and lecturers eat and sleep in the same place where the lectures are given. The absence of senior members, and the fact of spending day and night together in an isolated, peaceful place contribute to creating an informal atmosphere and facilitating interactions. Lectures of the thirteenth edition are centered around the following subjects: bulk reconstruction in AdS/CFT, twistor theory, AdS_2/CFT_1 and SYK, geometry and topology, and asymptotic charges.

Planck 2013 results. XIII. Galactic CO emission

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Alves, M. I. R.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartlett, J. G.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bock, J. J.; Bonaldi, A.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bridges, M.; Bucher, M.; Burigana, C.; Butler, R. C.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chary, R.-R.; Chen, X.; Chiang, H. C.; Chiang, L.-Y.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.-M.; Dempsey, J. T.; Désert, F.-X.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Falgarone, E.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Fukui, Y.; Galeotta, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Handa, T.; Hansen, F. K.; Hanson, D.; Harrison, D.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hily-Blant, P.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jewell, J.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Laureijs, R. J.; Lawrence, C. R.; Leonardi, R.; León-Tavares, J.; Lesgourgues, J.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maffei, B.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Matthai, F.; Mazzotta, P.; McGehee, P.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Moore, T. J. T.; Morgante, G.; Morino, J.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Nakajima, T.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Okuda, T.; Osborne, S.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Pasian, F.; Patanchon, G.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Starck, J.-L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Thomas, H. S.; Toffolatti, L.; Tomasi, M.; Torii, K.; Tristram, M.; Tucci, M.; Tuovinen, J.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; Wehus, I. K.; Yamamoto, H.; Yoda, T.; Yvon, D.; Zacchei, A.; Zonca, A.

2014-11-01

Rotational transition lines of CO play a major role in molecular radio astronomy as a mass tracer and in particular in the study of star formation and Galactic structure. Although a wealth of data exists for the Galactic plane and some well-known molecular clouds, there is no available high sensitivity all-sky survey of CO emission to date. Such all-sky surveys can be constructed using the Planck HFI data because the three lowest CO rotational transition lines at 115, 230 and 345 GHz significantly contribute to the signal of the 100, 217 and 353 GHz HFI channels, respectively. Two different component separation methods are used to extract the CO maps from Planck HFI data. The maps obtained are then compared to one another and to existing external CO surveys. From these quality checks the best CO maps, in terms of signal to noise ratio and/or residual contamination by other emission, are selected. Three different sets of velocity-integrated CO emission maps are produced with different trade-offs between signal-to-noise, angular resolution, and reliability. Maps for the CO J = 1 → 0, J = 2 → 1, and J = 3 → 2 rotational transitions are presented and described in detail. They are shown to be fully compatible with previous surveys of parts of the Galactic plane as well as with undersampled surveys of the high latitude sky. The Planck HFI velocity-integrated CO maps for the J = 1 → 0, J = 2 → 1, and J = 3 →2 rotational transitions provide an unprecedented all-sky CO view of the Galaxy. These maps are also of great interest to monitor potential CO contamination of the Planck studies of the cosmological microwave background.

Apollo XIII Spacecraft - Splashdown - South Pacific Ocean

NASA Image and Video Library

1970-04-17

S70-35652 (17 April 1970) --- The Apollo 13 spacecraft heads toward a splashdown in the South Pacific Ocean. The Apollo 13 Command Module splashed down in the South Pacific at 12:07:44 p.m., April 17, 1970. Note the capsule and its parachutes just visible against a gap in the dark clouds.

Stellar model chromospheres. XIII - M dwarf stars

NASA Technical Reports Server (NTRS)

Giampapa, M. S.; Worden, S. P.; Linsky, J. L.

1982-01-01

Single-component, homogeneous model chromospheres that are consistent with high-resolution profiles of the Ca II K line calibrated in surface flux units for three dMe and 2 dM stars observed at quiescent times are constructed. The models reveal several systematic trends. Large values of the ratio of T(min) to T(eff) are derived, indicating a large amount of nonradiative heating present in the upper photospheres of M dwarf stars. It is also found that the lower chromospheric temperature gradient is similar for all the M dwarf stars. Since for the models here the chromospheric K line emission strength is most sensitive to the total amount of chromospheric material present within the approximate temperature range T(min)-6000 K, increasing the emission strength is not simply due to increasing chromospheric temperature gradients. It is also found that both the electron density and electron temperature at one thermalization length in the K line below the top of the chromospheres are greater in the dMe stars than in the dM stars. The M dwarf models here have microturbulent velocities between 1 and 2 km/sec, which are much smaller than for solar chromosphere models.

38 CFR 36.4340 - Underwriting standards, processing procedures, lender responsibility, and lender certification.

Code of Federal Regulations, 2014 CFR

2014-07-01

... streamlined refinance loan would not increase the principal balance outstanding on the prior existing... refinancing loans; (vii) Little or no increase in shelter expense; (viii) Military benefits; (ix) Satisfactory... continuing nature, such as tax credits for child care; and (xiii) Tax benefits of home ownership. (6) The...

46 CFR 199.180 - Training and drills.

Code of Federal Regulations, 2014 CFR

2014-10-01

... survival craft engine and accessories; (xiii) The recovery of survival craft and rescue boats, including... and operating the lifeboat engine; and (vii) Operating davits used for launching the liferafts. (2) Abandon-ship drills should also include conducting a mock search and rescue of passengers or special...

46 CFR 199.180 - Training and drills.

Code of Federal Regulations, 2012 CFR

2012-10-01

... survival craft engine and accessories; (xiii) The recovery of survival craft and rescue boats, including... and operating the lifeboat engine; and (vii) Operating davits used for launching the liferafts. (2) Abandon-ship drills should also include conducting a mock search and rescue of passengers or special...

46 CFR 199.180 - Training and drills.

Code of Federal Regulations, 2013 CFR

2013-10-01

... survival craft engine and accessories; (xiii) The recovery of survival craft and rescue boats, including... and operating the lifeboat engine; and (vii) Operating davits used for launching the liferafts. (2) Abandon-ship drills should also include conducting a mock search and rescue of passengers or special...

75 FR 44144 - Washington: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-28

....19. 400(3)(c)(xiii)(A) Correction--the 265.300 Subpart word N--Landfills, carbonaceous related... recycling Subpart G exception from related; closure and 264.140, financial 265.140 Subpart responsibility H...) Correction--chang 264.143. e ``resource reclamation units'' to ``recycling units''. 620(4)(d)(iv...

Incentive Pay for Remotely Piloted Aircraft Career Fields

DTIC Science & Technology

2012-01-01

Fields C.1. Mathematical Symbols for Non-Stochastic Values and Shock Terms...78 C.2. Mathematical Symbols for Taste and Compensation . . . . . . . . . . . 79 xiii Summary Background and...manning requirement, even with the current incentive pays and reenlistment bonuses. 2 The mathematical foundations, data, and estimation methods for the

40 CFR 63.1207 - What are the performance testing requirements?

Code of Federal Regulations, 2011 CFR

2011-07-01

... incinerators, cement kilns, and lightweight aggregate kilns, you must commence the initial comprehensive... performance test operating conditions, as provided by paragraph (g)(1)(iii) of this section; (xiii) For cement... preheater or preheater/precalciner cement kilns with dual stacks, if you elect to use the emissions...

38 CFR 17.81 - Contracts for residential treatment services for veterans with alcohol or drug dependence or...

Code of Federal Regulations, 2010 CFR

2010-07-01

... the Department of Veterans Affairs, Office of Regulations Management (02D), Room 1154, 810 Vermont... management must agree that all the other residents in any building housing veterans will also have such...) Support for the individual desire for sobriety (alcohol/drug abuse-free life style). (xiii) Opportunities...

46 CFR 199.180 - Training and drills.

Code of Federal Regulations, 2010 CFR

2010-10-01

... survival craft engine and accessories; (xiii) The recovery of survival craft and rescue boats, including... and operating the lifeboat engine; and (vii) Operating davits used for launching the liferafts. (2) Abandon-ship drills should also include conducting a mock search and rescue of passengers or special...

46 CFR 199.180 - Training and drills.

Code of Federal Regulations, 2011 CFR

2011-10-01

... survival craft engine and accessories; (xiii) The recovery of survival craft and rescue boats, including... and operating the lifeboat engine; and (vii) Operating davits used for launching the liferafts. (2) Abandon-ship drills should also include conducting a mock search and rescue of passengers or special...

Tabulation of comet observations.

NASA Astrophysics Data System (ADS)

1985-04-01

Concerning comets: 1961 VIII Seki, 1962 III Seki-Lines, 1963 I Ikeya, 1963 III Alcock, 1964 VIII Ikeya, 1965 VIII Ikeya-Seki, 1966 V Kilston, 1967 II Rudnicki, 1968 I Ikeya-Seki, 1968 VI Honda, 1969 IX Tago-Sato-Kosaka, 1970 II Bennett, 1971 V Toba, 1973 XII Kohoutek, 1974 II P/Schwassmann-Wachmann 1, 1974 III Bradfield, 1975 IX Kobayashi-Berger-Milon, 1975 X Suzuki-Saigusa-Mori, 1975 XII Mori-Sato-Fujikawa, 1976 VI West, 1976 XI P/d'Arrest, 1979 X Bradfield, 1980 XI P/Encke, 1980 XIII P/Tuttle, 1980 XV Bradfield, 1981 II Panther, 1982i P/Halley, 1983 XIII P/Kopff, 1983n P/Crommelin, 1983v P/Hartley-IRAS, 1983w P/Clark, 1984c P/Neujmin, 1984f Shoemaker, 1984g P/Wolf-Harrington, 1984h P/Faye, 1984i Austin, 1984j P/Takamizawa, 1984k P/Arend-Rigaux, 1984m P/Schaumasse, 1984p Tsuchinshan 1, 1984q P/Shoemaker 1, 1984s Shoemaker, 1984t Levy-Rudenko.

Sylphella puccoon gen. n., sp. n. and two additional new species of aquatic oligochaetes (Lumbriculidae, Clitellata) from poorly-known lotic habitats in North Carolina (USA)

USGS Publications Warehouse

Rodriguez, Pilar; Fend, Steven V.; Lenat, David R.

2014-01-01

Three new species of Lumbriculidae were collected from floodplain seeps and small streams in southeastern North America. Some of these habitats are naturally acidic. Sylphella puccoon gen. n., sp. n. has prosoporous male ducts in X-XI, and spermathecae in XII-XIII. Muscular, spherical atrial ampullae and acuminate penial sheaths distinguish this monotypic new genus from other lumbriculid genera having similar arrangements of reproductive organs. Cookidrilus pocosinus sp. n. resembles its two subterranean, Palearctic congeners in the arrangement of reproductive organs, but is easily distinguished by the position of the spermathecal pores in front of the chaetae in X-XIII. Stylodrilus coreyi sp. n. differs from congeners having simple-pointed chaetae and elongate atria primarily by the structure of the male duct and the large clusters of prostate cells. Streams and wetlands of Southeastern USA have a remarkably high diversity of endemic lumbriculids, and these poorly-known invertebrates should be considered in conservation efforts.

An International Model of World-Class Education: The International Baccalaureate

ERIC Educational Resources Information Center

Hill, Ian

2012-01-01

This article posits that world-class education is international education, as defined by UNESCO, and presents International Baccalaureate (IB) programmes as examples of this phenomenon. It begins with the IB's 1960s origins in international schools, which educated the children of globally mobile parents who worked principally in the UN and its…

Leptospira Immunoglobulin-Like Protein B (LigB) Binds to Both the C-Terminal 23 Amino Acids of Fibrinogen αC Domain and Factor XIII: Insight into the Mechanism of LigB-Mediated Blockage of Fibrinogen α Chain Cross-Linking.

PubMed

Hsieh, Ching-Lin; Chang, Eric; Tseng, Andrew; Ptak, Christopher; Wu, Li-Chen; Su, Chun-Li; McDonough, Sean P; Lin, Yi-Pin; Chang, Yung-Fu

2016-09-01

The coagulation system provides a primitive but effective defense against hemorrhage. Soluble fibrinogen (Fg) monomers, composed of α, β and γ chains, are recruited to provide structural support for the formation of a hemostatic plug. Fg binds to platelets and is processed into a cross-linked fibrin polymer by the enzymatic clotting factors, thrombin and Factor XIII (FXIII). The newly formed fibrin-platelet clot can act as barrier to protect against pathogens from entering the bloodstream. Further, injuries caused by bacterial infections can be confined to the initial wound site. Many pathogenic bacteria have Fg-binding adhesins that can circumvent the coagulation pathway and allow the bacteria to sidestep containment. Fg expression is upregulated during lung infection providing an attachment surface for bacteria with the ability to produce Fg-binding adhesins. Fg binding by leptospira might play a crucial factor in Leptospira-associated pulmonary hemorrhage, the main factor contributing to lethality in severe cases of leptospirosis. The 12th domain of Leptospira immunoglobulin-like protein B (LigB12), a leptospiral adhesin, interacts with the C-terminus of FgαC (FgαCC). In this study, the binding site for LigB12 was mapped to the final 23 amino acids at the C-terminal end of FgαCC (FgαCC8). The association of FgαCC8 with LigB12 (ELISA, KD = 0.76 μM; SPR, KD = 0.96 μM) was reduced by mutations of both charged residues (R608, R611 and H614 from FgαCC8; D1061 from LigB12) and hydrophobic residues (I613 from FgαCC8; F1054 and A1065 from LigB12). Additionally, LigB12 bound strongly to FXIII and also inhibited fibrin formation, suggesting that LigB can disrupt coagulation by suppressing FXIII activity. Here, the detailed binding mechanism of a leptospiral adhesin to a host hemostatic factor is characterized for the first time and should provide better insight into the pathogenesis of leptospirosis.

Leptospira Immunoglobulin-Like Protein B (LigB) Binds to Both the C-Terminal 23 Amino Acids of Fibrinogen αC Domain and Factor XIII: Insight into the Mechanism of LigB-Mediated Blockage of Fibrinogen α Chain Cross-Linking

PubMed Central

Hsieh, Ching-Lin; Chang, Eric; Tseng, Andrew; Ptak, Christopher; Wu, Li-Chen; Su, Chun-Li; McDonough, Sean P.; Lin, Yi-Pin; Chang, Yung-Fu

2016-01-01

The coagulation system provides a primitive but effective defense against hemorrhage. Soluble fibrinogen (Fg) monomers, composed of α, β and γ chains, are recruited to provide structural support for the formation of a hemostatic plug. Fg binds to platelets and is processed into a cross-linked fibrin polymer by the enzymatic clotting factors, thrombin and Factor XIII (FXIII). The newly formed fibrin-platelet clot can act as barrier to protect against pathogens from entering the bloodstream. Further, injuries caused by bacterial infections can be confined to the initial wound site. Many pathogenic bacteria have Fg-binding adhesins that can circumvent the coagulation pathway and allow the bacteria to sidestep containment. Fg expression is upregulated during lung infection providing an attachment surface for bacteria with the ability to produce Fg-binding adhesins. Fg binding by leptospira might play a crucial factor in Leptospira-associated pulmonary hemorrhage, the main factor contributing to lethality in severe cases of leptospirosis. The 12th domain of Leptospira immunoglobulin-like protein B (LigB12), a leptospiral adhesin, interacts with the C-terminus of FgαC (FgαCC). In this study, the binding site for LigB12 was mapped to the final 23 amino acids at the C-terminal end of FgαCC (FgαCC8). The association of FgαCC8 with LigB12 (ELISA, KD = 0.76 μM; SPR, KD = 0.96 μM) was reduced by mutations of both charged residues (R608, R611 and H614 from FgαCC8; D1061 from LigB12) and hydrophobic residues (I613 from FgαCC8; F1054 and A1065 from LigB12). Additionally, LigB12 bound strongly to FXIII and also inhibited fibrin formation, suggesting that LigB can disrupt coagulation by suppressing FXIII activity. Here, the detailed binding mechanism of a leptospiral adhesin to a host hemostatic factor is characterized for the first time and should provide better insight into the pathogenesis of leptospirosis. PMID:27622634

What skills should new internal medicine interns have in july? A national survey of internal medicine residency program directors.

PubMed

Angus, Steven; Vu, T Robert; Halvorsen, Andrew J; Aiyer, Meenakshy; McKown, Kevin; Chmielewski, Amy F; McDonald, Furman S

2014-03-01

The transition from medical student to intern may cause stress and burnout in new interns and the delivery of suboptimal patient care. Despite a formal set of subinternship curriculum guidelines, program directors have expressed concern regarding the skill set of new interns and the lack of standardization in that skill set among interns from different medical schools. To address these issues, the Accreditation Council for Graduate Medical Education's Next Accreditation System focuses on the development of a competency-based education continuum spanning undergraduate, graduate, and continuing medical education. In 2010, the Clerkship Directors in Internal Medicine subinternship task force, in collaboration with the Association of Program Directors in Internal Medicine survey committee, surveyed internal medicine residency program directors to determine which competencies or skills they expected from new medical school graduates. The authors summarized the results using categories of interest. In both an item rank list and free-text responses, program directors were nearly uniform in ranking the skills they deemed most important for new interns-organization and time management and prioritization skills; effective communication skills; basic clinical skills; and knowing when to ask for assistance. Stakeholders should use the results of this survey as they develop a milestone-based curriculum for the fourth year of medical school and for the internal medicine subinternship. By doing so, they should develop a standardized set of skills that meet program directors' expectations, reduce the stress of transitions across the educational continuum, and improve the quality of patient care.

38 CFR 26.6 - Environmental documents.

Code of Federal Regulations, 2011 CFR

2011-07-01

... significant impact on, official local or regional zoning or comprehensive land use plans; and, (xiii...) Environmental Impact Statements. The head of each VA element shall include a detailed written statement “in... Regulations, 40 CFR part 1502. An environmental impact statement shall be prepared in accordance with the...

7 CFR 1485.13 - Application process and strategic plan.

Code of Federal Regulations, 2012 CFR

2012-01-01

... business cards; (viii) The cost of seasonal greeting cards; (ix) Fees for office parking; (x) The cost of subscriptions to publications; (xi) The cost of activities conducted overseas; (xii) Credit card fees; (xiii... fees or similar sales expenditures; (x) Membership fees in clubs and social organizations; and (xi) Any...

[Bio-nanoscience and bio-nanotechnology: social and ethical aspects].

PubMed

Martín-Lomas, Manuel

2006-01-01

This article is an abstract of a conference with the same title presented at the XIII Jornadas sobre Derecho y Genoma Humano and is basically centred in a report for the Royal Society and the Royal Academy of Engineering entitled Nanoscience and Nanotechnology made publicly available July 2004.

38 CFR 36.4340 - Underwriting standards, processing procedures, lender responsibility, and lender certification.

Code of Federal Regulations, 2013 CFR

2013-07-01

... equity in refinancing loans; (vii) Little or no increase in shelter expense; (viii) Military benefits...; (xii) Tax credits of a continuing nature, such as tax credits for child care; and (xiii) Tax benefits... supplied in the Consumer Expenditure Survey (CES) published by the Department of Labor's Bureau of Labor...

38 CFR 36.4340 - Underwriting standards, processing procedures, lender responsibility, and lender certification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... equity in refinancing loans; (vii) Little or no increase in shelter expense; (viii) Military benefits...; (xii) Tax credits of a continuing nature, such as tax credits for child care; and (xiii) Tax benefits... supplied in the Consumer Expenditure Survey (CES) published by the Department of Labor's Bureau of Labor...

38 CFR 36.4340 - Underwriting standards, processing procedures, lender responsibility, and lender certification.

Code of Federal Regulations, 2012 CFR

2012-07-01

... equity in refinancing loans; (vii) Little or no increase in shelter expense; (viii) Military benefits...; (xii) Tax credits of a continuing nature, such as tax credits for child care; and (xiii) Tax benefits... supplied in the Consumer Expenditure Survey (CES) published by the Department of Labor's Bureau of Labor...

42 CFR 417.166 - Waiver of assurances.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CONTINUED) MEDICARE PROGRAM HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS, AND HEALTH CARE... law; or (2) The HMO shows good cause, consistent with the purposes of title XIII of the PHS Act. (b... the reorganization can only be approved with the waiver of the assurances. (ii) State laws governing...

12 CFR 27.3 - Recordkeeping requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... employed by the current employer of the applicant(s). For self-employed persons, the number of continuous years self-employed. (xiii) Gross total monthly income of each applicant, comprising the sum of normal... or disability income and income from part-time employment. For self-employed persons, include the...

27 CFR 9.108 - Ozark Mountain.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Creek; (xii) Then northeastward along Rock Creek to Petit Jean Creek; (xiii) Then generally northeastward and eastward along Petit Jean Creek until it becomes the Petit Jean River (on the Russellville map); (xiv) Then generally eastward along the Petit Jean River, flowing through Blue Mountain Lake, until the...

27 CFR 9.108 - Ozark Mountain.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Creek; (xii) Then northeastward along Rock Creek to Petit Jean Creek; (xiii) Then generally northeastward and eastward along Petit Jean Creek until it becomes the Petit Jean River (on the Russellville map); (xiv) Then generally eastward along the Petit Jean River, flowing through Blue Mountain Lake, until the...

27 CFR 9.108 - Ozark Mountain.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Creek; (xii) Then northeastward along Rock Creek to Petit Jean Creek; (xiii) Then generally northeastward and eastward along Petit Jean Creek until it becomes the Petit Jean River (on the Russellville map); (xiv) Then generally eastward along the Petit Jean River, flowing through Blue Mountain Lake, until the...

27 CFR 9.108 - Ozark Mountain.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Creek; (xii) Then northeastward along Rock Creek to Petit Jean Creek; (xiii) Then generally northeastward and eastward along Petit Jean Creek until it becomes the Petit Jean River (on the Russellville map); (xiv) Then generally eastward along the Petit Jean River, flowing through Blue Mountain Lake, until the...

Reinventing US Internal Migration Studies in the Age of International Migration

PubMed Central

Ellis, Mark

2014-01-01

I argue that researchers have sidelined attention to issues raised by US internal migration as they shifted focus to the questions posed by the post-1960s rise in US immigration. In this paper, I offer some reasons about why immigration has garnered more attention and why there needs to be greater consideration of US internal migration and its significant and myriad social, economic, political, and cultural impacts. I offer three ideas for motivating more research into US internal geographic mobility that would foreground its empirical and conceptual connections to international migration. First, there should be more work on linked migration systems investigating the connections between internal and international flows. Second, the questions asked about immigrant social, cultural, and economic impacts and adaptations in host societies should also be asked about internal migrants. Third, and more generally, migration researchers should jettison the assumption that the national scale is the pre-eminent delimiter of migration types and processes. Some groups can move easily across borders; others are constrained in their moves within countries. These subnational scales and constraints will become more visible if migration research decentres the national from its theory and empirics. PMID:24839406

Reinventing US Internal Migration Studies in the Age of International Migration.

PubMed

Ellis, Mark

2012-03-01

I argue that researchers have sidelined attention to issues raised by US internal migration as they shifted focus to the questions posed by the post-1960s rise in US immigration. In this paper, I offer some reasons about why immigration has garnered more attention and why there needs to be greater consideration of US internal migration and its significant and myriad social, economic, political, and cultural impacts. I offer three ideas for motivating more research into US internal geographic mobility that would foreground its empirical and conceptual connections to international migration. First, there should be more work on linked migration systems investigating the connections between internal and international flows. Second, the questions asked about immigrant social, cultural, and economic impacts and adaptations in host societies should also be asked about internal migrants. Third, and more generally, migration researchers should jettison the assumption that the national scale is the pre-eminent delimiter of migration types and processes. Some groups can move easily across borders; others are constrained in their moves within countries. These subnational scales and constraints will become more visible if migration research decentres the national from its theory and empirics.

Decontamination of Streptococci biofilms and Bacillus cereus spores on plastic surfaces with DC and pulsed corona discharges

NASA Astrophysics Data System (ADS)

Koval'ová, Zuzana; Tarabová, Kataŕna; Hensel, Karol; Machala, Zdenko

2013-02-01

Cold air plasmas of DC and pulsed corona discharges: positive streamers and negative Trichel pulses were used for bio-decontamination of Streptococci biofilm and Bacillus cereus spores on polypropylene plastic surfaces. The reduction of bacterial population (evaluated as log10) in the biofilm on plastic surfaces treated by DC corona reached 2.4 logs with 10 min treatment time and 3.3 logs with 2 min treatment time with water spraying. The enhancement of plasma biocidal effects on the biofilm by electro-spraying of water through a hollow needle high-voltage electrode was investigated. No significant polarity effect was found with DC corona. Pulsed corona was demonstrated slightly more bactericidal for spores, especially in the negative polarity where the bacterial population reduction reached up to 2.2 logs at 10 min exposure time. Contribution to the Topical Issue "13th International Symposium on High Pressure Low Temperature Plasma Chemistry (Hakone XIII)", Edited by Nicolas Gherardi, Henryca Danuta Stryczewska and Yvan Ségui.

International Perspectives on the Profile of Highly Talented International Business Professionals

ERIC Educational Resources Information Center

van Heugten, Petra; Heijne-Penninga, Marjolein; Robbe, Patricia; Jaarsma, Debbie; Wolfensberger, Marca

2017-01-01

There is a global demand for talented managers and leaders. To meet this demand, higher education institutions are developing talent programs. However, international perception of talent is diffuse. In this study, our profile of highly talented international business professionals was internationally validated by 172 participants, representing…

International Mindedness: Conceptualizations and Curriculum in an International School in Brazil

ERIC Educational Resources Information Center

Dewey, Nelson Peter

2017-01-01

This dissertation is a qualitative, single case study of an international school in Brazil that explores how school administrators and teachers conceptualize international mindedness, and how it is developed within the curriculum of the International Baccalaureate Diploma Program. I provide a rich description of the context, developing four themes…

Measuring International Service Outcomes: Implications for International Social Work Field Placements

ERIC Educational Resources Information Center

Lough, Benjamin J.; McBride, Amanda Moore; Sherraden, Margaret S.

2012-01-01

International field placements are a unique educational opportunity for social work students to develop the skills they need for social work practice in a globalized world; however, outcomes of international placements have not been rigorously studied. This article reports on the International Volunteer Impacts Survey (IVIS), a 48-item survey…

Benefits of International Collaboration on the International Space Station

NASA Technical Reports Server (NTRS)

Hasbrook, Pete; Robinson, Julie A.; Brown Tate, Judy; Thumm, Tracy; Cohen, Luchino; Marcil, Isabelle; De Parolis, Lina; Hatton, Jason; Umezawa, Kazuo; Shirakawa, Masaki;

7 CFR 1485.16 - Contribution rules.

Code of Federal Regulations, 2014 CFR

2014-01-01

... business cards that target a foreign audience; (viii) The cost of seasonal greeting cards; (ix) Fees for... conducted overseas; (xii) Credit card fees; (xiii) The cost of any independent evaluation or audit that is...) Membership fees in clubs and social organizations; and (xi) Any expenditure for an activity prior to CCC's...

7 CFR 1485.16 - Contribution rules.

Code of Federal Regulations, 2013 CFR

2013-01-01

... business cards that target a foreign audience; (viii) The cost of seasonal greeting cards; (ix) Fees for... conducted overseas; (xii) Credit card fees; (xiii) The cost of any independent evaluation or audit that is...) Membership fees in clubs and social organizations; and (xi) Any expenditure for an activity prior to CCC's...

77 FR 76871 - Approval and Promulgation of Implementation Plans; State of Colorado; Regional Haze State...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-31

... nitrogen oxides. xiii. The initials NPS mean or refer to National Park Service. xiv. The initials PM 2.5..., nitrogen deposition, and mercury emissions and deposition. The State spent considerable time and conducted sequential and extended hearings to develop a plan which seeks to balance a number of variables beyond those...

46 CFR 56.01-10 - Plan approval.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ballast piping. (vii) Tank cleaning piping. (viii) Condenser circulating water piping. (ix) Vent, sound....) (xii) Cargo piping. (xiii) Hot water heating systems if the temperature is greater than 121 °C(250 °F... substantiate their compliance with the regulations of this subchapter; (3) A thermal stress analysis is not...

Single-cycle Optical Pulses and Isolated Attosecond Pulse Generation

DTIC Science & Technology

2012-02-29

picosecond green light from a frequency-doubled hybrid cryogenic Yb:YAG laser system,” 36 UFO /HFSW 2009 (Arcachon, France, Aug. 31-Sept. 4, 2009...High Fields Short Wavelength,” ( UFO VII – HFSW XIII), Arcachon, France, August 31 – September 4, 2009 (invited). 25) Kyung-Han Hong, Juliet Gopinath

7 CFR 25.1 - Applicability and scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Reconciliation Act of 1993, title XIII, subchapter C, part I (Round I), the Taxpayer Relief Act of 1997, title IX, subtitle F (Round II), the Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations Act, 1999 (Public Law 105-277) (Round IIS), and the Community Renewal Tax Relief...

7 CFR 25.1 - Applicability and scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Reconciliation Act of 1993, title XIII, subchapter C, part I (Round I), the Taxpayer Relief Act of 1997, title IX, subtitle F (Round II), the Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations Act, 1999 (Public Law 105-277) (Round IIS), and the Community Renewal Tax Relief...

7 CFR 25.1 - Applicability and scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Reconciliation Act of 1993, title XIII, subchapter C, part I (Round I), the Taxpayer Relief Act of 1997, title IX, subtitle F (Round II), the Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations Act, 1999 (Public Law 105-277) (Round IIS), and the Community Renewal Tax Relief...

78 FR 15988 - Self-Regulatory Organizations; the NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-13

.... ``dark venues'' or ``dark pools''). QCST orders, pursuant to Rule 4758(a)(1)(A)(xiii), check the System for available shares and simultaneously route to select dark venues and to certain low cost exchanges... Web site ( http://www.sec.gov/rules/sro.shtml ). Copies of the submission, all subsequent amendments...

Why International?

ERIC Educational Resources Information Center

Falcetta, Frank M.

1993-01-01

Discusses the benefits of international programs at community colleges based on the example of Middlesex Community College in Bedford, Massachusetts. Indicates that international programs broaden the perspective of the campus, generate new revenue and positive media exposure, contribute to professional development of faculty and staff, and provide…

International Curriculums.

ERIC Educational Resources Information Center

Neal, Larry L.

This workshop presentation on international curriculums in the field of parks, recreation, leisure, cultural services, and travel/tourism comments that the literature is replete with articles addressing what the field is about, but not about curriculum issues, models, and structure. It reports an international survey of 12 college educators…

International programs

NASA Technical Reports Server (NTRS)

1973-01-01

Brief summaries are given of NASA's participation in international space programs. This participation can be categorized in five principal areas: manned space flight, space sciences, space applications, ground support of space operations, and cooperative international aeronautics research. All projects are carried out on a cooperative or reimbursable basis.

Neurology and international organizations.

PubMed

Mateen, Farrah J

2013-07-23

A growing number of international stakeholders are engaged with neurologic diseases. This article provides a brief overview of important international stakeholders in the practice of neurology, including global disease-specific programs, United Nations agencies, governmental agencies with international influence, nongovernmental organizations, international professional organizations, large private donors, private-public partnerships, commercial interests, armed forces, and universities and colleges. The continued engagement of neurologists is essential for the growing number of international organizations that can and should incorporate neurologic disease into their global agendas.

Processes of Internal and International Migration from Chitwan, Nepal.

PubMed

Bohra, Pratikshya; Massey, Douglas S

2009-01-01

In this study we examine which factors predict internal and international migration from Chitwan, a flat valley located in the South-Central region of Nepal, seeking to measure the effect of theoretically specified variables such as human capital, social capital, physical capital, and neighborhood socioeconomic conditions while controlling for demographic variables. We use data from the Chitwan Valley Family Study (CVFS) to estimate a series of discrete time event history models of first and repeat migration to three competing destinations: other locations within Chitwan, other districts within Nepal, and places outside of Nepal. Results support hypotheses derived from neoclassical economics, the theory of new economics of migration, social capital theory, and cumulative causation theory. Our results underscore the need for a synthetic theoretical model that incorporates factors operating at the individual, household, and community levels. The use of multiple explanatory models yields a clearer picture of the forces driving internal and international migration from rural districts in developing nations such as Nepal.

Processes of Internal and International Migration from Chitwan, Nepal

PubMed Central

Bohra, Pratikshya; Massey, Douglas S.

2011-01-01

In this study we examine which factors predict internal and international migration from Chitwan, a flat valley located in the South-Central region of Nepal, seeking to measure the effect of theoretically specified variables such as human capital, social capital, physical capital, and neighborhood socioeconomic conditions while controlling for demographic variables. We use data from the Chitwan Valley Family Study (CVFS) to estimate a series of discrete time event history models of first and repeat migration to three competing destinations: other locations within Chitwan, other districts within Nepal, and places outside of Nepal. Results support hypotheses derived from neoclassical economics, the theory of new economics of migration, social capital theory, and cumulative causation theory. Our results underscore the need for a synthetic theoretical model that incorporates factors operating at the individual, household, and community levels. The use of multiple explanatory models yields a clearer picture of the forces driving internal and international migration from rural districts in developing nations such as Nepal. PMID:21423821

Neurology and international organizations

PubMed Central

2013-01-01

A growing number of international stakeholders are engaged with neurologic diseases. This article provides a brief overview of important international stakeholders in the practice of neurology, including global disease-specific programs, United Nations agencies, governmental agencies with international influence, nongovernmental organizations, international professional organizations, large private donors, private–public partnerships, commercial interests, armed forces, and universities and colleges. The continued engagement of neurologists is essential for the growing number of international organizations that can and should incorporate neurologic disease into their global agendas. PMID:23877795

International Cooperation at NASA

NASA Astrophysics Data System (ADS)

Tawney, Timothy; Feldstein, Karen

International cooperation is a cornerstone principle of NASA’s activities, especially within the activities of the Science Mission Directorate. Nearly two thirds of the flight missions in which NASA leads or participates involve international cooperation. Numerous ground based activities also rely on international cooperation, whether because of unique expertise, unique geography, or the need for a global response. Going forward, in an era of tighter budgets and a more integrated global perspective, NASA and the rest of the space agencies around the world will be forced to work more closely together, in a broader array of activities than ever before, in order to be able to afford to push the boundaries of space exploration. The goal of this presentation is to provide an overview of NASA’s current international science cooperative activities. It will include a discussion of why NASA conducts international cooperation and look at the mechanisms through which international cooperation can occur at NASA, including peer-to-peer development of relationships. It will also discuss some of the limiting factors of international cooperation, such as export control, and ways in which to manage those constraints. Finally, the presentation would look at some of the present examples where NASA is working to increase international cooperation and improve coordination. Case studies will be used to demonstrate these mechanisms and concepts. For example, NASA continues to participate in international coordination groups such as the International Mars Exploration Working Group (IMEWG) and International Space Exploration Coordination Group (ISECG), but is expanding into new areas as well. NASA is one of the leaders in expanding and improving international coordination in the area of Near-Earth Object detection, characterization, and mitigation. Having participated in the first meetings of such groups as the International Asteroid Warning Network (IAWN) and Space Missions Planning

International Education: The International Baccalaureate, Montessori and Global Citizenship

ERIC Educational Resources Information Center

Brunold-Conesa, Cynthia

2010-01-01

The International Baccalaureate (IB) programs and Montessori education both claim to promote values associated with global citizenship in order to help prepare students for new challenges presented by an increasingly globalized world. While the IB's secondary programs are widespread in international schools, Montessori programs at that level are…

Benefits of International Collaboration on the International Space Station

NASA Technical Reports Server (NTRS)

Robinson, Julie A.; Hasbrook, Pete; Tate Brown, Judy; Thumm, Tracy; Cohen, Luchino; Marcil, Isabelle; De Parolis, Lina; Hatton, Jason; Umezawa, Kazuo; Shirakawa, Masaki;

77 FR 29633 - Alta Wind VII, LLC, Alta Wind IX, LLC, Alta Wind X, LLC, Alta Wind XI, LLC, Alta Wind XII, LLC...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-18

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-68-000] Alta Wind VII, LLC, Alta Wind IX, LLC, Alta Wind X, LLC, Alta Wind XI, LLC, Alta Wind XII, LLC, Alta Wind XIII, LLC, Alta Wind XIV, LLC, Alta Wind XV, LLC, Alta Windpower Development, LLC, TGP Development Company, LLC...

32 CFR 865.114 - Decisional document.

Code of Federal Regulations, 2010 CFR

2010-07-01

... punishment). (xii) Conviction by court-martial. (xiii) Prior military service and type of discharge received. (3) A list of the type of documents submitted by or on behalf of the applicant (including a written... documentary evidence), if any. (4) A statement whether the applicant testified, and a list of the type of...

Improving Soldier and Unit Effectiveness with the Stryker Brigade Combat Team Warfighters’ Forum

DTIC Science & Technology

2011-01-01

Figures S.1. Differences Attributable to the ICEA Handbook During a Training Rotation . . . . . . . . . . . xiii 2.1. Distribution of Respondents...of Differences Attributable to the Handbook During a Training Rotation ...in an SBCT that received the ICEA did significantly better on tactical tasks during combat training center rotations than platoons that did not

The History of Disability Services in Higher Education

ERIC Educational Resources Information Center

Madaus, Joseph W.

2011-01-01

In 2002, Brinckerhoff, McGuire, and Shaw observed that the field of postsecondary education and disability services had "moved through its adolescence and was embarking on adulthood" (xiii). Indeed, the field had undergone rapid expansion nationwide in the prior 30 years and grew into a full-fledged profession within higher education (Jarrow…

Military Review. Volume 80, Number 4, July-August 2000

DTIC Science & Technology

2000-08-01

Politics, Book 7, written in 350 B.C., trans. Benjamin Jowett, xiii, 1331 b24b39. 3.Stephen Covey, The 7 Habits of Highly Effective People : Restoring the...daily activities of subordinates. Stephen Covey, The 7 Habits of Highly Effective People : Restoring the Character Ethic, uses the notion of alignment to

Energy Policy Act Transportation Rate Study: Final Report on Coal Transportation

EIA Publications

2000-01-01

This is the final in a series of reports prepared for the U.S. Congress by the Secretary of Energy on coal distribution and transportation rates as mandated by Title XIII, Section 1340, Establishment of Data Base and Study of Transportation Rates, of the Energy Policy Act of 1992 (P.L. 102-486).

Improving Operational Effectiveness of Tactical Long Endurance Unmanned Aerial Systems (TALEUAS) by Utilizing Solar Power

DTIC Science & Technology

2014-06-01

Speed xiii TEK Total Energy Compensated TSP traveling salesman problem UAV unmanned aerial vehicle UDP user datagram protocol UKF unscented...discretized map, and use the map to optimally solve the navigation task. The optimal navigation solution utilizes the well-known “ travelling salesman problem ...2 C. FORMULATION OF THE PROBLEM .................................................. 3 D

Development of an NPS Middle Ultraviolet Spectrograph (Mustang) Electronic Interface

DTIC Science & Technology

1991-12-01

connecting coaxial shield ................................ 140 xiii Figure 7-12 Encode Command Signal (top) and Video Data Signal (bottom) after connecting...coaxial shield ................................................ 142 Figure 7-13 Data Ready Signal (top) and Video Data Signal (bottom) after...connecting coaxial shield ....................................................... 142 Figure 7-14 Word Clock (top) and Gated Enable Signal Rising Edge (bottom

Comparing International Curriculum Systems: The International Instructional Systems Study

ERIC Educational Resources Information Center

Creese, Brian; Gonzalez, Alvaro; Isaacs, Tina

2016-01-01

This paper sets out the main findings of the International Instructional Systems Study (IISS), conducted by the UCL Institute of Education and funded by the Center on International Education Benchmarking (CIEB). The study examined the instructional systems and intended curricula of six "high performing" countries and two US states. The…

International University Freshmen's Perceptions on Culturally Diverse Community and Internal Stakeholders' Tactics

ERIC Educational Resources Information Center

Atabekova, Anastasia A.; Belousov, Alexander A.; Yastrebov, Oleg A.

2016-01-01

The paper explores first-year students' feelings about international university campus. Increasing globalisation of education raises a number of issues related not only to internationally accepted standards of qualifications and degrees, curriculum development, faculty competences, but also to domestic and international students' tolerance,…

International Telecommunication Control: International Law and the Ordering of Satellite and Other Forms of International Broadcasting.

ERIC Educational Resources Information Center

Smith, Delbert D.

The need for and the available alternatives for international telecommunication controls are examined, and a functional approach to this area of law is offered. Information from a number of areas is collected and examined as it relates to the basic problem. These areas include general principles of international law, the activities of the…

International Data Archive and Analysis Center. I. International Relations Archive. II. Voluntary International Coordination. III. Attachments.

ERIC Educational Resources Information Center

Miller, Warren; Tanter, Raymond

The International Relations Archive undertakes as its primary goals the acquisition, management and dissemination of international affairs data. The first document enclosed is a copy of the final machine readable codebook prepared for the data from the Political Events Project, 1948-1965. Also included is a copy of the final machine-readable…

Cultural Diversity among Heads of International Schools: Potential Implications for International Education

ERIC Educational Resources Information Center

Slough-Kuss, Yvonne

2014-01-01

This article considers the influence that regional associations of international schools have on individual school members. The role of heads of international schools is explored in terms of their collective regional community influence on the fundamental school level. A revision of Thompson's model of international education is proposed…

Teaching International Economics and Trade--Concepts in International Relations

ERIC Educational Resources Information Center

Starbird, Caroline; DeBoer, Dale; Pettit, Jenny

2004-01-01

The purpose of this book is to introduce students to real-life issues in international economics. The sections of the book are: (1) The Advantages of Trade; (2) Judging NAFTA; (3) Does Globalization Benefit Poor Countries?; (4) Pocket Guide to International Financial Institutions; (5) What Do You Know about the WTO?; (6) Free Trade and Shifting…

The ELISE II Project: A Digital Image Library for Europe.

ERIC Educational Resources Information Center

Strunz, Bob; Waters, Mairead

This paper describes the progress made under the ELISE II electronic image library project from a technical standpoint. The ELISE II project is a European-wide initiative that aims to provide a comprehensive electronic image library service for Europe. It is funded under the European Commission, DG XIII-E, Telematics for Libraries Initiative. The…

7 CFR 2.22 - Under Secretary for Marketing and Regulatory Programs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Consultative Group to Eliminate the Use of Child Labor and Forced Labor in Imported Agricultural Products. (2..., control or eradicate foot-and-mouth disease and other foreign animal diseases (21 U.S.C. 113a); (xiii) The... States in control and eradication of plant and animal diseases and pests; (xv) The Federal Noxious Weed...

7 CFR 2.22 - Under Secretary for Marketing and Regulatory Programs.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Consultative Group to Eliminate the Use of Child Labor and Forced Labor in Imported Agricultural Products. (2..., control or eradicate foot-and-mouth disease and other foreign animal diseases (21 U.S.C. 113a); (xiii) The... States in control and eradication of plant and animal diseases and pests; (xv) The Federal Noxious Weed...

7 CFR 2.22 - Under Secretary for Marketing and Regulatory Programs.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Consultative Group to Eliminate the Use of Child Labor and Forced Labor in Imported Agricultural Products. (2..., control or eradicate foot-and-mouth disease and other foreign animal diseases (21 U.S.C. 113a); (xiii) The... States in control and eradication of plant and animal diseases and pests; (xv) The Federal Noxious Weed...

7 CFR 2.22 - Under Secretary for Marketing and Regulatory Programs.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Consultative Group to Eliminate the Use of Child Labor and Forced Labor in Imported Agricultural Products. (2..., control or eradicate foot-and-mouth disease and other foreign animal diseases (21 U.S.C. 113a); (xiii) The... States in control and eradication of plant and animal diseases and pests; (xv) The Federal Noxious Weed...

International Perspectives on Plagiarism and Considerations for Teaching International Trainees

PubMed Central

Heitman, Elizabeth; Litewka, Sergio

2010-01-01

In the increasingly global community of biomedical science and graduate science education, many US academic researchers work with international trainees whose views on scientific writing and plagiarism can be strikingly different from US norms. Although a growing number of countries and international professional organizations identify plagiarism as research misconduct, many international trainees come from research environments where plagiarism is ill-defined and even commonly practiced. Two research-ethics educators consider current perspectives on plagiarism around the world and contend that US research-training programs should focus on trainees’ scientific writing skills and acculturation, not simply on preventing plagiarism. PMID:21194646

Innovation and International Education.

ERIC Educational Resources Information Center

Edmonds, Edward L.

Objectives and realities of education for international understanding, cooperation, and peace are examined. Information is presented in six major sections. In Section I, various meanings of international education are explored. In addition, central concerns of international education are identified, including respect for human rights and…

A Realistic International Economics.

ERIC Educational Resources Information Center

Culbertson, John M.

1987-01-01

Criticizes college textbooks for adopting a "party line" of laissez-faire economic doctrine which asserts the benefits of free trade. Offers an alternative interpretation of international trade, covering such topics as the effect of unregulated international trade on wage levels, and international lending. (JDH)

Preparing for the primary care clinic: an ambulatory boot camp for internal medicine interns

PubMed Central

Esch, Lindsay M.; Bird, Amber-Nicole; Oyler, Julie L.; Lee, Wei Wei; Shah, Sachin D.; Pincavage, Amber T.

2015-01-01

Introduction Internal medicine (IM) interns start continuity clinic with variable ambulatory training. Multiple other specialties have utilized a boot camp style curriculum to improve surgical and procedural skills, but boot camps have not been used to improve interns’ ambulatory knowledge and confidence. The authors implemented and assessed the impact of an intern ambulatory boot camp pilot on primary care knowledge, confidence, and curricular satisfaction. Methods During July 2014, IM interns attended ambulatory boot camp. It included clinically focused case-based didactic sessions on common ambulatory topics as well as orientation to the clinic and electronic medical records. Interns anonymously completed a 15-question pre-test on topics covered in the boot camp as well as an identical post-test after the boot camp. The interns were surveyed regarding their confidence and satisfaction. Results Thirty-eight interns participated in the boot camp. Prior to the boot camp, few interns reported confidence managing common outpatient conditions. The average pre-test knowledge score was 46.3%. The average post-test knowledge score significantly improved to 76.1% (p<0.001). All interns reported that the boot camp was good preparation for clinics and 97% felt that the boot camp boosted their confidence. Conclusions The ambulatory boot camp pilot improved primary care knowledge, and interns thought it was good preparation for clinic. The ambulatory boot camp was well received and may be an effective way to improve the preparation of interns for primary care clinic. Further assessment of clinical performance and expansion to other programs and specialties should be considered. PMID:26609962

The International Heliophysical Year

NASA Technical Reports Server (NTRS)

Thompson, Barbara J.

2007-01-01

In 1957 a program of international research, inspired by the International Polar Years of 1882 and 1932, was organized as the International Geophysical Year (IGY) to study global phenomena of the Earth and geospace. Fifty years later, the world s space science community will again come together for international programs of scientific collaboration: the International Heliophysical Year (IHY), the Electronic Geophysical Year (eGY), and the International Polar Year (IPY) 2007. This time, research will extend out into the Heliosphere to focus on solar-terrestrial-planetary interactions. The ambitious plans for the IHY, eGY and IPY incorporate the activities of scientists in 191 nations, as well as the IGY Gold Historical Preservation initiative, plus a series of coordinated campaigns involving more than 100 instruments and models, education and public outreach programs, a developing nations instrument development program, and opportunities for supported research worldwide. The presentation will focus on the efforts and operations which will make these activities possible.

Study on internal to surface fingerprint correlation using optical coherence tomography and internal fingerprint extraction

NASA Astrophysics Data System (ADS)

Darlow, Luke Nicholas; Connan, James

2015-11-01

Surface fingerprint scanners are limited to a two-dimensional representation of the fingerprint topography, and thus, are vulnerable to fingerprint damage, distortion, and counterfeiting. Optical coherence tomography (OCT) scanners are able to image (in three dimensions) the internal structure of the fingertip skin. Techniques for obtaining the internal fingerprint from OCT scans have since been developed. This research presents an internal fingerprint extraction algorithm designed to extract high-quality internal fingerprints from touchless OCT fingertip scans. Furthermore, it serves as a correlation study between surface and internal fingerprints. Provided the scanned region contains sufficient fingerprint information, correlation to the surface topography is shown to be good (74% have true matches). The cross-correlation of internal fingerprints (96% have true matches) is substantial that internal fingerprints can constitute a fingerprint database. The internal fingerprints' performance was also compared to the performance of cropped surface counterparts, to eliminate bias owing to information level present, showing that the internal fingerprints' performance is superior 63.6% of the time.

Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism.

PubMed

Shaya, S A; Saldanha, L J; Vaezzadeh, N; Zhou, J; Ni, R; Gross, P L

2016-01-01

ESSENTIALS: Does thrombus stability alter the presentation of venous thromboembolism and do anticoagulants alter this? In a murine model, we imaged a femoral vein thrombus and quantified emboli in the pulmonary arteries. Dabigatran decreases thrombus stability via factor XIII increasing embolization and pulmonary emboli. This cautions against the unapproved use of dabigatran for acute initial treatment of deep vein thrombosis. Venous thromboembolism (VTE) is a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE). Thrombus instability possibly contributes to progression of DVT to PE, and direct thrombin inhibitors (DTIs) may alter this. To develop a model to assess thrombus stability and its link to PE burden, and identify whether DTIs, in contrast to low-molecular-weight heparin (LMWH), alter this correlation. Twelve minutes after ferric chloride-induced thrombus formation in the femoral vein of female mice, saline, dalteparin (LMWH) or dabigatran (DTI) was administered. Thrombus size and embolic events breaking off from the thrombus were quantified before treatment and at 10-min intervals after treatment for 2 h using intravital videomicroscopy. Lungs were stained for the presence of PE. Thrombus size was similar over time and between treatment groups. Total and large embolic events and pulmonary emboli were highest after treatment with dabigatran. Variations in amounts of pulmonary embolic events were not attributed to variations in thrombus size. Large embolic events correlated with the number of emboli per lung slice independent of treatment. Embolization in factor XIII deficient (FXIII(-/-) ) saline-treated mice was greater than that in wild-type (WT) saline-treated mice, but was similar to WT dabigatran-treated mice. We have developed a mouse model of VTE that can quantify emboli and correlate this with PE burden. Consistent with clinical data, dabigatran, a DTI, acutely decreases thrombus stability and increases PE burden compared with

International Mindedness in Practice: The Evidence from International Baccalaureate Schools

ERIC Educational Resources Information Center

Hacking, Elisabeth Barratt; Blackmore, Chloe; Bullock, Kate; Bunnell, Tristan; Donnelly, Michael; Martin, Susan

2018-01-01

International Mindedness is an overarching construct related to multilingualism, intercultural understanding and global engagement (Hill, 2012). The concept is central to the International Baccalaureate (IB) and sits at the heart of its education policies and programmes. The aim of this research study was to examine systematically how schools…

International certification in developing countries: the role of internal and external institutional pressure.

PubMed

Fikru, Mahelet G

2014-11-01

This paper examines the different internal and external institutional factors that affect the decision of businesses in developing countries to adopt international certification (IC). Past studies focus on pressure from international laws, the role of multinationals, and businesses mimicking practices of their counterparts in developed countries. This paper finds that, in addition to these external factors, internal factors may have a significant role. Even though environmental regulation is weak in developing countries, governments do not ignore industrial pollution and casualties. They respond by increasing bureaucratic regulations for businesses and this can affect the decision to adopt IC. Furthermore, internal pressure may come from workers' unions that push for a safe and healthy working environment. Published by Elsevier Ltd.

Unit III: International Conflict.

ERIC Educational Resources Information Center

Maxey, Phyllis

1983-01-01

This lesson helps students understand the global network involved in international events. Students have an opportunity to examine the impact of international law and the role of international organizations, national governments, and private individuals in the effort to secure the release of United States hostages in Iran. (AM)

Reflections on international medical law.

PubMed

Wattad, Mohammed S; Hrevtsova, Radmyla Yu

2011-12-01

Does international medical law exist, in the first place, as an independent area of study? If so, is it urgently required in an era of comparative studies? Namely, to what extent, if at all, international studies differ from comparative ones? Besides, what are the particular characteristics of such international discipline? Namely, what are the particular features of this field that elaborate on our legal and scientific understanding in sketching possible definition for this notion of "international medical law?" In addition, how does international medical law correlate with health, ethics and health policies in our globalized world? And finally, what are the challenges that might face the international community, once the concept of "international medical law" is acknowledged? This papers aims at establishing the conceptual grounds for these questions, thus calling for the acknowledgment of a new field of study described as "international medical law".

International perspectives on plagiarism and considerations for teaching international trainees.

PubMed

Heitman, Elizabeth; Litewka, Sergio

2011-01-01

In the increasingly global community of biomedical science and graduate science education, many US academic researchers work with international trainees whose views on scientific writing and plagiarism can be strikingly different from US norms. Although a growing number of countries and international professional organizations identify plagiarism as research misconduct, many international trainees come from research environments where plagiarism is ill-defined and even commonly practiced. Two research-ethics educators consider current perspectives on plagiarism around the world and contend that US research-training programs should focus on trainees' scientific writing skills and acculturation, not simply on preventing plagiarism. Copyright © 2011 Elsevier Inc. All rights reserved.

Utopia, University and Architecture: A Journey that Changed the Design of Contemporary Universities

ERIC Educational Resources Information Center

Calvo-Sotelo, Pablo Campos

2006-01-01

In 1927, a group of advisors to King Alfonso XIII of Spain, led by the architect Modesto Lopez-Otero, set out for the United States and Canada. Previously, they had visited a number of European cities where they examined the medieval architectural form of some famous universities. Inspired by a Utopian vision, the journey to the New World studied…

11 CFR 300.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 6, 2002, the receipt of such funds prior to November 6, 2002 shall have no bearing on determining... if we can count on you for $10,000.” (xiii) “Your contribution to this campaign would mean a great... entire Democratic ticket in November.” (vi) A Federal officeholder says: “Our Senator has done a great...

11 CFR 300.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 6, 2002, the receipt of such funds prior to November 6, 2002 shall have no bearing on determining... if we can count on you for $10,000.” (xiii) “Your contribution to this campaign would mean a great... entire Democratic ticket in November.” (vi) A Federal officeholder says: “Our Senator has done a great...

11 CFR 300.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 6, 2002, the receipt of such funds prior to November 6, 2002 shall have no bearing on determining... if we can count on you for $10,000.” (xiii) “Your contribution to this campaign would mean a great... entire Democratic ticket in November.” (vi) A Federal officeholder says: “Our Senator has done a great...

11 CFR 300.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 6, 2002, the receipt of such funds prior to November 6, 2002 shall have no bearing on determining... if we can count on you for $10,000.” (xiii) “Your contribution to this campaign would mean a great... entire Democratic ticket in November.” (vi) A Federal officeholder says: “Our Senator has done a great...

Catholic Labor Education and the Association of Catholic Trade Unionists. Instructing Workers to Christianize the Workplace

ERIC Educational Resources Information Center

Lubienecki, Paul

2015-01-01

This article analyzes the effect of the American Catholic Church, through its program of specialized labor education, on the growth and development of organized labor in the twentieth century. With the proclamation of Pope Pius XI's encyclical Quadragesimo Anno (1931), he requested that the Church complete the work began by Pope Leo XIII in 1891…

Identification of Decision Support Concepts for the Planning of Air Force Immediate Contingencies Operations

DTIC Science & Technology

2010-03-01

that is becoming the norm in military operations, especial rapid response. Significance : The context of the work for this project focused on one...Time constraint variance ................................................................... 37 DRDC Valcartier CR 2010-353 xiii 3.5.8.1...employment activities that are normally recurring in nature and fall within the delegated authority of an appointed standing operational Commander

Test Plan Framework for Cross Domain Solution (CDS) Devices

DTIC Science & Technology

2010-06-01

modification to the CASTER software to reflect the latest changes to RDAC is being discussed by the developers with input by the independent labs and NSA...7 xii THIS PAGE INTENTIONALLY LEFT BLANK xiii LIST OF ABBREVIATIONS AND ACRONYMS CASTER Certification...protecting information and information systems from unauthorized access, use, disclosure, disruption, modification , or destruction. While this is a

Defining the Role and Responsibility of the Fire Service Within Homeland Security

DTIC Science & Technology

2010-03-01

Occupational Safety and Health NPS Naval Postgraduate School NRF National Response Framework OSHA Occupational Safety and Health Administration ...Kingdom USAR Urban Search and Rescue USFA United States Fire Administration USMA United States Military Academy xiii ACKNOWLEDGMENTS I want...Association (NFPA), the Occupational Safety and Health Administration (OSHA), the United States Fire Administration (USFA), and the National Institute for

[Growth of the neurocranium].

PubMed

Hodacová, Z; Skalská, H

1998-01-01

The present study demonstrates the results of evaluation of growth changes of the neurocranium in a set of 98 human skulls of immature individuals aged 6-18/20/ years from the XIII.-XVIII. century. Craniometric values were matched with the corresponding values measured on the skulls of the same age groups from the IX. century and IX.-XII. centuries.

International Relations. International Perspectives on Higher Education Research. Volume 3

ERIC Educational Resources Information Center

Tight, Malcolm, Ed.

2005-01-01

This is the third volume of International Perspectives on Higher Education Research, a series which aims to feature something of the variety of research being undertaken into higher education systems and issues outside of North America. The theme of this volume is International Relations, or how students, academics, universities and higher…

International Business Education: Identifying the Emergent Topics in International Business and Their Relevance for Knowledge Development.

ERIC Educational Resources Information Center

Yeoh, Poh-Lin

2001-01-01

Sampled faculty in international business (IB) to better understand emerging themes in that area. Seven major topical areas were uncovered: general knowledge of IB, international trade and institutions, cross-cultural issues, managing global operations, international ethics, international monetary systems, and international political/regulatory…

Speckle Interferometry at the US Naval Observatory. XIII

DTIC Science & Technology

2007-10-01

18443+3940 ............................. STF 2382 AB 6.394 348.9 2.35 1 0.3 0.06 Mason et al. (2004a) 0.2 0.03 Novakovic & Todorovic (2005) 18443+3940...1952, Bull. Astron. Paris, 16, 263 Novakovic , B., & Todorovic, N. 2005, Circ. d’Inf. 157 Olevic, D. 2002, Circ. d’Inf. 147 Olevic, D., & Cvetkovic, Z

Undertaking an International Assignment.

ERIC Educational Resources Information Center

Kitinoja, Lisa; And Others

Agricultural and extension educators interested in international agricultural development must answer several questions to become oriented within the field before undertaking an international assignment. The questions are as follows: (1) why do you want to work internationally? (2) what do you have to offer as a professional? and (3) what is your…

Standardized sign-out reduces intern perception of medical errors on the general internal medicine ward.

PubMed

Salerno, Stephen M; Arnett, Michael V; Domanski, Jeremy P

2009-01-01

Prior research on reducing variation in housestaff handoff procedures have depended on proprietary checkout software. Use of low-technology standardization techniques has not been widely studied. We wished to determine if standardizing the process of intern sign-out using low-technology sign-out tools could reduce perception of errors and missing handoff data. We conducted a pre-post prospective study of a cohort of 34 interns on a general internal medicine ward. Night interns coming off duty and day interns reassuming care were surveyed on their perception of erroneous sign-out data, mistakes made by the night intern overnight, and occurrences unanticipated by sign-out. Trainee satisfaction with the sign-out process was assessed with a 5-point Likert survey. There were 399 intern surveys performed 8 weeks before and 6 weeks after the introduction of a standardized sign-out form. The response rate was 95% for the night interns and 70% for the interns reassuming care in the morning. After the standardized form was introduced, night interns were significantly (p < .003) less likely to detect missing sign-out data including missing important diseases, contingency plans, or medications. Standardized sign-out did not significantly alter the frequency of dropped tasks or missed lab and X-ray data as perceived by the night intern. However, the day teams thought there were significantly less perceived errors on the part of the night intern (p = .001) after introduction of the standardized sign-out sheet. There was no difference in mean Likert scores of resident satisfaction with sign-out before and after the intervention. Standardized written sign-out sheets significantly improve the completeness and effectiveness of handoffs between night and day interns. Further research is needed to determine if these process improvements are related to better patient outcomes.

The International Mycological Association: its history in brief with summaries of its International Mycological Congresses and diverse international relationships.

PubMed

Simmons, Emory G

2010-06-01

This history presents a review of International Mycological Association activities, its international congresses, and its relationships with regional mycological associations as well as with international organizations of other scientific disciplines. The IMA was organized in 1971 during the First Mycological Congress (IMC-1) convened at Exeter, U.K. In the period 1971 to 2010, nine international congresses have been held, each with its own organizational structure but under the guidance of one of the successive inter-Congress management groups of IMA officers and executive committee members. The congress list includes Exeter, U.K.; Tampa, U.S.A.; Tokyo, Japan; Regensburg, Germany; Vancouver, Canada; Jerusalem, Israel; Oslo, Norway; Cairns, Australia; and Edinburgh, Scotland. Inter-congress activities of each IMA executive group are summarized. The characteristics of each congress are surveyed as to organization, programming, attendance numbers, finances, and satellite meetings.The IMA has sponsored the establishment of Regional Mycological Associations beginning in 1977 and has lent operational funding. Regional associations currently are functional and hold their own regional congresses in Africa, Asia, Australasia, Europe, and Latin America. The relationships of the IMA with other organizations recognized within the supra-national International Council of Scientific Unions are discussed.

What Is International about International Schools? An Institutional Legitimacy Perspective

ERIC Educational Resources Information Center

Bunnell, Tristan; Fertig, Michael; James, Chris

2016-01-01

In recent years, the number of International Schools around the world has increased rapidly largely as a result of growth of new forms of International Schools, which differ markedly from the traditional forms. These new forms: are often operated on a for-profit commercial basis; are usually for children from the local (indigenous), wealthy…

Internal and International Migration Across the Urban Hierarchy in Albania.

PubMed

Lerch, Mathias

2016-01-01

The interactions between the processes of urbanization and international migration in less developed and transition countries have important repercussions for socioeconomic development, but are not well understood. Based on the retrospective data from the Albanian Living Standards Measurement Survey 2008, we first assess the geography of migration in terms of the rural-urban continuum, the urban hierarchy and the outside world since 1990. We then investigate the spatio-temporal diffusion of rural-to-urban and international movements using survival models. Results reveal an immediate onset of large-scale rural exodus, despite the post-communist crisis. Internal migrants mainly moved to the capital, bypassing secondary cities, and were predominantly female. Initially, international migrants were primarily men who tended to originate from the main urban agglomerations. The diffusion of opportunities to emigrate down the urban hierarchy and across the sexes then redirected the rural exodus abroad, despite domestic economic development. This evolution in population mobility is related to the gendered patterns and interlinkages of the two flows, as well as to rising inequalities within the urban hierarchy.

International utilization and operations

NASA Technical Reports Server (NTRS)

Goldberg, Stanley R.

1989-01-01

The international framework of the Space Station Freedom Program is described. The discussion covers the U.S. space policy, international agreements, international Station elements, overall program management structure, and utilization and operations management. Consideration is also given to Freedom's user community, Freedom's crew, pressurized payload and attached payload accommodations, utilization and operations planning, user integration, and user operations.

Internal Auditing for School Districts.

ERIC Educational Resources Information Center

Cuzzetto, Charles

This book provides guidelines for conducting internal audits of school districts. The first five chapters provide an overview of internal auditing and describe techniques that can be used to improve or implement internal audits in school districts. They offer information on the definition and benefits of internal auditing, the role of internal…

International Student Success

ERIC Educational Resources Information Center

Smith, Clayton

2016-01-01

This article, with a focus on North American postsecondary education, identifies international students as a strategic enrollment management institutional priority; presents themes in the international student retention, satisfaction, and success research literature; and describes related best practices. It also presents the findings from an…

Exploration of the perceptions of emergency physicians and interns regarding the medical documentation practices of interns.

PubMed

Isoardi, Jonathon; Spencer, Lyndall; Sinnott, Michael; Nicholls, Kim; O'Connor, Angela; Jones, Fleur

2013-08-01

The primary objective of the present study was to learn the factors that influence the documentation practices of ED interns. A second objective was to identify the expectations of emergency physicians (EPs) towards the medical record documentation of ED interns. A qualitative design was adopted using semi-structured interviews in convenience samples drawn from both groups. Eighteen interviews were conducted with intern volunteers and 10 with EP volunteers. One (5%) intern and two (20%) EPs had received medical documentation training. Factors that encouraged interns' documentation included: patient acuity (the more critical the condition, the more comprehensive the documentation) and the support of senior colleagues. Inhibiting factors included uncertainty about how much to write, and the shift being worked (interns indicated they wrote less at night). Factors of consequence to senior personnel included the apparent reluctance of interns to document management plans. They noted that interns frequently confine their notes to assessment, investigations and treatments, whereas EPs preferred records that demonstrated intern thought processes and included such matters as future actions to follow immediate treatment. A positive theme that emerged included the high level of support interns received from their senior colleagues. Another theme, the influence of patient acuity, held both positive and negative implications for intern writing practices. The lack of formal training is an impediment to the production of useful medical records by ED interns. One solution proposed by both interns and senior personnel was the introduction of the subject into intern education programmes. © 2013 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

Tabulation of comet observations.

NASA Astrophysics Data System (ADS)

1993-10-01

Concerning comets: 1955 III Mrkos, 1955 IV Bakharev-Macfarlane-Krienke, 1955 V Honda, 1956 III Mrkos, 1956 IV P/Olbers, 1957 III Arend-Roland, 1957 V Mrkos, 1958 III Burnham, 1959 VIII P/Giacobini-Zinner, 1960 II Burnham, 1973 XII Kohoutek, 1974 III Bradfield, 1975 IX Kobayashi-Berger-Milon, 1975 X Suzuki-Saigusa-Mori, 1975 XI Bradfield, 1975 XII Mori-Sato-Fujikawa, 1976 IV Bradfield, 1976 VI West, 1979 VII Bradfield, 1980 X P/Stephan-Oerma, 1980 XII Meier, 1980 XIII P/Tuttle, 1981 II Panther, 1981 IV P/Borrelly, 1981 XIX P/Swift-Gehrels, 1982 I Bowell, 1982 IV P/Grigg-Skjellerup, 1982 VI Austin, 1982 VII P/d'Arrest, 1982 VIII P/Churyumov-Gerasimenko, 1983 V Sugano-Saigusa-Fujikawa, 1983 VII IRAS-Araki-Alcock, 1983 X P/Tempel 2, 1983 XI P/Tempel 1, 1983 XIII P/Kopff, 1983 XIV P/IRAS, 1983 XV Shoemaker, 1984 III P/Hartley-IRAS, 1984 IV P/Crommelin, 1984 XI P/Faye, 1984 XIII Austin, 1984 XIV P/Wild 2, 1984 XVI P/Shoemaker 1, 1984 XXIII Levy-Rudenko, 1985 I P/Tsuchinshan 1, 1985 XIII P/Giacobini-Zinner, 1985 XV P/Giclas, 1985 XVI P/Ciffréo, 1985 XVII Hartley-Good, 1985 XVIII P/Shoemaker 3, 1985 XIX Thiele, 1986 I P/Boethin, 1986 III P/Halley, 1986 VIII P/Machholz, 1986 XVII Levy, 1986 XVIII Terasako, 1987 II Sorrells, 1987 VII Wilson, 1987 XIX P/Schwassmann-Wachmann 2, 1987 XXI Levy, 1987 XXIII Rudenko, 1987 XXIV P/Brooks 2, 1987 XXVII P/Kohoutek, 1987 XXIX Bradfield, 1988 IV Furuyama, 1988 XIV P/Tempel 2, 1989 III Shoemaker, 1989 XV P/Schwassmann-Wachmann 1, 1989 XIX Okazaki-Levy-Rudenko, 1990 V Austin, 1990 XVII Tsuchiya-Kiuchi, 1990 XX Levy, 1990 XXI P/Encke, 1990 XXVI Arai, 1991 I P/Metcalf-Brewington, 1991 XV P/Hartley 2, 1991 XVII P/Arend-Rigaux, 1991a1 Shoemaker-Levy, 1991g1 Zanotta-Brewington, 1992c P/Howell, 1992d Tanaka-Machholz, 1992e P/Singer Brewster, 1992f P/Shoemaker-Levy 8, 1992h Spacewatch, 1992j P/Ashbrook-Jackson, 1992t P/Swift-Tuttle, 1992u P/Väisälä 1, 1992w P/Slaughter-Burnham, 1992x P/Schaumasse, 1992y Shoemaker, 1993a Mueller, 1993d Mueller

The Student Internationals. An Analysis of International and Regional Student Organizations. Final Report.

ERIC Educational Resources Information Center

Altbach, Philip G.

The work is a report of a historical study of several international student organizations in their political and educational contexts to learn whether they, in fact, constitute a real student movement on a world scale. After tracing the growth of such organizations as the International Union of Students and the International Student Conference and…

Training the intern: The value of a pre-intern year in preparing students for practice.

PubMed

Dare, Anna; Fancourt, Nicholas; Robinson, Elizabeth; Wilkinson, Tim; Bagg, Warwick

2009-08-01

To evaluate the clinical and professional development that occurs during a New Zealand trainee intern year in preparation for the first house officer role. A quantitative questionnaire was distributed to all trainee interns (year 6) and year 5 medical students in New Zealand at the end of the 2007 academic year. This survey assessed self-reported competency and performance across clinical, professional and role development domains. Response rate was 65% (457/702). Compared to year 5 students, trainee interns reported significantly greater competence and performance levels across all three domains. The greatest improvement occurred in the independent performance of procedural skills (trainee interns: 77%, year 5: 35%, p < 0.001) and clinical tasks (trainee interns: 94%, year 5: 56%, p < 0.001) and in the level of clinical responsibility taken (p < 0.001). At the end of the trainee intern year, 92% of students felt prepared to be a junior doctor, versus only 53% at the end of their 5th year (p < 0.0001). The trainee intern year is important in preparing graduates for the intern role. The year affords increased responsibility and practical experience, whilst retaining an educational focus, facilitating the move from competence towards performance. Preparedness for practice was substantially higher following the New Zealand trainee intern year than has been reported with other pre-intern placements.

78 FR 68853 - International Medical Device Regulators Forum; Medical Device Single Audit Program International...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-15

...] International Medical Device Regulators Forum; Medical Device Single Audit Program International Coalition Pilot... Drug Administration (FDA) is announcing participation in the Medical Device Single Audit Program International Coalition Pilot Program. The Medical Device Single Audit Program (MDSAP) was designed and...

49 CFR 173.220 - Internal combustion engines, self-propelled vehicles, mechanical equipment containing internal...

Code of Federal Regulations, 2010 CFR

2010-10-01

... vehicles, mechanical equipment containing internal combustion engines, and battery powered vehicles or... equipment containing internal combustion engines, and battery powered vehicles or equipment. (a... internal combustion engine, or a battery powered vehicle or equipment is subject to the requirements of...

Interns at an International, Humanitarian Organization: Career Pathways and Meaning Making

ERIC Educational Resources Information Center

Mather, Peter C.

2008-01-01

This qualitative study examined the career shaping experiences and related meaning making processes of 12 interns at The Carter Center, an international, humanitarian organization. Experiences shaping participants' careers were grouped into the following themes--academics and intellectual curiosity; travel abroad; religion; relationships--family,…

The successes and limitations of international law and the International Court of Justice.

PubMed

Suter, Keith

2004-01-01

The first two sections of this article deal with the irony that international law has severe limitations, yet it also has a good record for compliance. The third section introduces the International Court of Justice (ICJ), and the fourth section deals specifically with the limitations of the ICJ. The article concludes with some ideas for action. Its main point is that international law is often a neglected topic, even by non-governmental organisations (NGOs). International law needs to be brought in from the cold, and there should be more support from the NGO community for the ICJ.

Internal connections and conversations: the internalized other interview in bereavement work.

PubMed

Moules, Nancy J

Much of the work of grief lies in the ways the bereaved learn to maintain connection to the deceased in their lives, while living alongside the physical absence of them. The theory of an Internalized Other Interview is that we carry within ourselves impressions, memories, beliefs, assessments, doctrines, and codes of those who have shaped our lives through relationship. This internalized community of commentators is active in our lives on a day-to-day basis, but when someone dies, their active voice in the dialogue is shifted to a perceived inactivity. However, I argue that, despite the physical absence of the other, the voice continues to resonate and interact in our formation of our worlds. How our loved ones live on inside us influences who we are in the world and in our bereavement. As a result of our research and clinical work, I have come to believe that the active interviewing of the deceased person as internalized in the bereaved can have powerful and healing effects. In this article, I share the results of the research related to this intervention, describe the history located in Internalized Other Interviewing, and offer a transcription of an Internalized Other Interview with a young man and his family who recently lost both his brother and father.

Brief International Cognitive Assessment for MS (BICAMS): international standards for validation.

PubMed

Benedict, Ralph H B; Amato, Maria Pia; Boringa, Jan; Brochet, Bruno; Foley, Fred; Fredrikson, Stan; Hamalainen, Paivi; Hartung, Hans; Krupp, Lauren; Penner, Iris; Reder, Anthony T; Langdon, Dawn

2012-07-16

An international expert consensus committee recently recommended a brief battery of tests for cognitive evaluation in multiple sclerosis. The Brief International Cognitive Assessment for MS (BICAMS) battery includes tests of mental processing speed and memory. Recognizing that resources for validation will vary internationally, the committee identified validation priorities, to facilitate international acceptance of BICAMS. Practical matters pertaining to implementation across different languages and countries were discussed. Five steps to achieve optimal psychometric validation were proposed. In Step 1, test stimuli should be standardized for the target culture or language under consideration. In Step 2, examiner instructions must be standardized and translated, including all information from manuals necessary for administration and interpretation. In Step 3, samples of at least 65 healthy persons should be studied for normalization, matched to patients on demographics such as age, gender and education. The objective of Step 4 is test-retest reliability, which can be investigated in a small sample of MS and/or healthy volunteers over 1-3 weeks. Finally, in Step 5, criterion validity should be established by comparing MS and healthy controls. At this time, preliminary studies are underway in a number of countries as we move forward with this international assessment tool for cognition in MS.

Benefits of International Collaboration on the International Space Station

NASA Technical Reports Server (NTRS)

Hasbrook, Pete; Robinson, Julie A.; Cohen, Luchino; Marcil, Isabelle; De Parolis, Lina; Hatton, Jason; Shirakawa, Masaki; Karabadzhak, Georgy; Sorokin, Igor V.; Valentini, Giovanni

2017-01-01

The International Space Station is a valuable platform for research in space, but the benefits are limited if research is only conducted by individual countries. Through the efforts of the ISS Program Science Forum, international science working groups, and interagency cooperation, international collaboration on the ISS has expanded as ISS utilization has matured. Members of science teams benefit from working with counterparts in other countries. Scientists and institutions bring years of experience and specialized expertise to collaborative investigations, leading to new perspectives and approaches to scientific challenges. Combining new ideas and historical results brings synergy and improved peer-reviewed scientific methods and results. World-class research facilities can be expensive and logistically complicated, jeopardizing their full utilization. Experiments that would be prohibitively expensive for a single country can be achieved through contributions of resources from two or more countries, such as crew time, up- and down mass, and experiment hardware. Cooperation also avoids duplication of experiments and hardware among agencies. Biomedical experiments can be completed earlier if astronauts or cosmonauts from multiple agencies participate. Countries responding to natural disasters benefit from ISS imagery assets, even if the country has no space agency of its own. Students around the world participate in ISS educational opportunities, and work with students in other countries, through open curriculum packages and through international competitions. Even experiments conducted by a single country can benefit scientists around the world, through specimen sharing programs and publicly accessible "open data" repositories. For ISS data, these repositories include GeneLab, the Physical Science Informatics System, and different Earth data systems. Scientists can conduct new research using ISS data without having to launch and execute their own experiments

Internal audit consider the implications.

PubMed

Baumgartner, Grant D; Hamilton, Angela

2004-06-01

Internal audit can not only allay external and internal concerns about appropriateness of business operations, but also help improve efficiency and the bottom line. To get an internal audit function under way, healthcare organizations need to obtain board buy-in, form an audit committee of the board, determine resources needed, perform a risk assessment, and develop an internal audit plan.

Rotor internal friction instability

NASA Technical Reports Server (NTRS)

Bently, D. E.; Muszynska, A.

1985-01-01

Two aspects of internal friction affecting stability of rotating machines are discussed. The first role of internal friction consists of decreasing the level of effective damping during rotor subsynchronous and backward precessional vibrations caused by some other instability mechanisms. The second role of internal frication consists of creating rotor instability, i.e., causing self-excited subsynchronous vibrations. Experimental test results document both of these aspects.

Hanford internal dosimetry program manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carbaugh, E.H.; Sula, M.J.; Bihl, D.E.

1989-10-01

This document describes the Hanford Internal Dosimetry program. Program Services include administrating the bioassay monitoring program, evaluating and documenting assessments of internal exposure and dose, ensuring that analytical laboratories conform to requirements, selecting and applying appropriate models and procedures for evaluating internal radionuclide deposition and the resulting dose, and technically guiding and supporting Hanford contractors in matters regarding internal dosimetry. 13 refs., 16 figs., 42 tabs.

Australia and international treaties: population.

PubMed

Hugo, G

1995-05-01

"The separation of environmental and population issues globally is reflected in the fact that the setting of international agendas to tackle them was for all intents and purposes undertaken at separate international meetings--the Earth Summit in Rio de Janeiro in 1992 and the International Population Conference in Cairo in 1994. This paper presents an overview of Australia's international involvement in population issues and suggests that until recently Australia had played a minor political role in international population initiatives primarily, and perhaps ironically, because it has been a world leader in demographic research and teaching for several decades." excerpt

International Education Programs.

ERIC Educational Resources Information Center

Charles, Richard F.

In response to global changes and a growing focus on international affairs, Foothill and De Anza Colleges have developed a number of international education programs. Since their beginnings, both colleges have hosted full-time students from other countries under the F-1 Visa Program. Another program, Campus Abroad, is a partnership arrangement…

International Pesticide Regulations

Science.gov Websites

; Environment Human Health Animal Health Safe Use Practices Food Safety Environment Air Water Soil Wildlife Ingredients Low-Risk Pesticides Organic Pesticide Ingredients Pesticide Incidents Human Exposure Pet Exposure - World Health Organization (WHO) International Agencies: International Websites on Pesticides - OECD

International Intelligence Forum 2002

DTIC Science & Technology

2002-01-01

International Intelligence Forum 2002 PCN 46737 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection...Intelligence Forum 2002 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f...Std Z39-18 INTERNATIONAL INTELLIGENCE FORUM -3 The Joint Military Intelligence College created the International Intelligence Fellows Program

Globalisation of international health.

PubMed

Walt, G

1998-02-07

40 years ago, activities in international health were the domain of WHO, governments (based on bilateral agreements), and non-governmental organisations. This has changed. Today, new players (such as the World Bank and, increasingly, the World Trade Organisation) have an influence on international health. As globalisation of trade and markets takes hold, new coalitions and alliances are forming to examine and deal with the direct and indirect consequences on health. This paper examines the changing context of cooperation in international health, and voices concerns about rising potential inequalities in health, both within and between countries. The question of how such changes will affect the actions of organisations working in international health is also addressed.

Transition to international classification of disease version 10, clinical modification: the impact on internal medicine and internal medicine subspecialties.

PubMed

Caskey, Rachel N; Abutahoun, Angelos; Polick, Anne; Barnes, Michelle; Srivastava, Pavan; Boyd, Andrew D

2018-05-04

The US health care system uses diagnostic codes for billing and reimbursement as well as quality assessment and measuring clinical outcomes. The US transitioned to the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) on October, 2015. Little is known about the impact of ICD-10-CM on internal medicine and medicine subspecialists. We used a state-wide data set from Illinois Medicaid specified for Internal Medicine providers and subspecialists. A total of 3191 ICD-9-CM codes were used for 51,078 patient encounters, for a total cost of US $26,022,022 for all internal medicine. We categorized all of the ICD-9-CM codes based on the complexity of mapping to ICD-10-CM as codes with complex mapping could result in billing or administrative errors during the transition. Codes found to have complex mapping and frequently used codes (n = 295) were analyzed for clinical accuracy of mapping to ICD-10-CM. Each subspecialty was analyzed for complexity of codes used and proportion of reimbursement associated with complex codes. Twenty-five percent of internal medicine codes have convoluted mapping to ICD-10-CM, which represent 22% of Illinois Medicaid patients, and 30% of reimbursements. Rheumatology and Endocrinology had the greatest proportion of visits and reimbursement associated with complex codes. We found 14.5% of ICD-9-CM codes used by internists, when mapped to ICD-10-CM, resulted in potential clinical inaccuracies. We identified that 43% of diagnostic codes evaluated and used by internists and that account for 14% of internal medicine reimbursements are associated with codes which could result in administrative errors.

Deceptive Tactics for Protecting Cities Against Vehicle Borne Improvised Explosive Devices

DTIC Science & Technology

2008-03-01

burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instruction, searching...INTENTIONALLY LEFT BLANK xiii LIST OF ABBREVIATIONS ABS Agent Based Simulation ANA Agent Network Attack DVF Detection Value Function GIS Geographic...any other behavior (than perceptive) may be advantageous to the attacker. - A communicative behavior proves particularly effective over time for the

Descriptive Summaries of the Research, Development, Test and Evaluation, Army Appropriation FY 1982. Supporting Data FY 1982. Supporting Data FY 1982, Budget Estimate Submitted to Congress January 1981, Amended 30 March 1981. Volume III.

DTIC Science & Technology

1981-01-01

ACTIVITIES .......... ............................ 111-548 3/ de ~ &04A.... ~UNCLASSIFIED xiii 0- 4 UNCLASSIFIED FY 1932 ROTE CONGRESSIONAI. DESCRIPTIVE...Title: Comeunicatiois gnlineerin De -elo pmnt DOD Mission Area: i256 - Tactical Communications Sudget Activity: 04 - TactictI Programs Into the...tconditions ot heavy miiltary traffic, high speeds, and severe weather. Army Remote Sensors (REMS) were used to provide 4-cnrity of the Olympic Village complex

Implementing and Evaluating an Innovative Approach to Simulation Training Acquisitions

DTIC Science & Technology

2006-01-01

busi- ness model, compares it with other approaches for buying simulations and simulation training, reviews economic theories relevant to the model, and...Points in Common with Other Approaches but Also Some Distinctive Characteristics ........................... 53 Contents vii CHAPTER FOUR The Economic ...Appropriate? .................... 65 4.3. Summary of Key Findings from Economic Theory .............. 72 xiii Summary In the wake of the failure of the Joint

Comparative Analysis of a High Bypass Turbofan Using a Pulsed Detonation Combustor

DTIC Science & Technology

2007-03-01

Thrust Specific Fuel Consumption . . . . . . . . . . . . . 67 xiii List of Abbreviations Abbreviation Page PDE Pulsed Detonation Engine...past ten years to develop pulsed det- onation engines ( PDE ) as a means of aircraft propulsion. Detonation combustion holds the promise of a more...aviation engine, and detonation creates more of it than previous aircraft engines. It is hoped that a marriage of the PDE with traditional

Tourism in Peru: The Missing Strategy for Economic and Social Development

DTIC Science & Technology

2006-06-01

Lima , 1970-1996.......................................12 xii THIS PAGE INTENTIONALLY LEFT BLANK xiii...time. Not two miles outside of Lima did things not only change, but they changed drastically. High rise buildings, upscale hotels, and very chic...natural resources. This is the case for Peru. Not only does the country hold a wealth of minerals, but it also possesses a plethora of beaches

Osteogenesis Imperfecta

PubMed Central

Sam, Justin Easow; Dharmalingam, Mala

2017-01-01

Osteogenesis imperfecta is a common heritable connective tissue disorder. Nearly ninety percent are due to Type I collagen mutations. Type I-IV are autosomal dominant, and Type VI–XIII are autosomal recessive. They are Graded 1-5 based on severity. Genomic testing is done by collagen analysis from fibroblasts. The mainstay of treatment is bisphosphonate therapy. The prognosis is variable. PMID:29285457

Naval Arms Control: A Post-Cold War Reappraisal

DTIC Science & Technology

1991-06-01

94 A . BACKGRO UN D ......................................................................................... 94 B. WHY ...control, but that an appropriate time may come to exist in the future. For reasons why naval arms control may make more sense in the future, but not...34. Current Research on Peace And Violence. Tampere Peace Research Institute, Tampere Finland, Vol XIII, No. 2, 1990, pp. 65-86. For reasons why naval

Developing a Resilient Green Cellular Network

DTIC Science & Technology

2013-12-01

to provide BS autonomy from grid power through alternative energy, such as: fuel cells and xiii renewable photovoltaic (PV), wind energy...stations with adequate backup power or utilizing alternative/renewable energy technology such as photovoltaic or wind power to allow them to...mitigating strategies with the consensus view on BSs migrating away from grid power , to renewable energy ( photovoltaic ), and alternative fuels. 40

40 CFR 721.5185 - Morpholine, 4-(1-oxo-2-propenyl)-.

Code of Federal Regulations, 2010 CFR

2010-07-01

...), (a)(5)(i), (a)(5)(ii), (a)(5)(iii), (a)(5)(xii), (a)(5)(xiii), (a)(5)(xiv), (a)(5)(xv), (a)(6)(v), (b) (concentration set at 0. 1 percent), and (c). The following material has been tested in accordance with the American Society for Testing Materials (ASTM) F739 method and found by EPA to satisfy the consent order's...

Modern Advances to the Modular Fly-Away Kit (MFLAK) to Support Maritime Interdiction Operations

DTIC Science & Technology

2007-09-01

combined Indonesia- Malaysia -Singapore-Thailand-U.S. R&D effort to investigate commercial-off-the- shelf (COTS) Command and Control, Communications...Operations and Applied Science & Technology Studies (COASTS). COASTS is a combined Indonesia- Malaysia -Singapore-Thailand-U.S. R&D effort to investigate...Message Authentication Code MALSINDO Malaysia , Indonesia and Singapore xiii Mbps Megabits per Second MCP Mission Capability Package MCSC Marine

Is international junior success a reliable predictor for international senior success in elite combat sports?

PubMed

Li, Pingwei; De Bosscher, Veerle; Pion, Johan; Weissensteiner, Juanita R; Vertonghen, Jikkemien

2018-05-01

Currently in the literature, there is a dearth of empirical research that confirms whether international junior success is a reliable predictor for future international senior success. Despite the uncertainty of the junior-senior relationship, federations and coaches still tend to use junior success as a predictor for long-term senior success. A range of former investigations utilising a retrospective lens has merely focused on success that athletes attained at junior level competitions. Success that was achieved at senior-level competitions but at a junior age was relatively ignored. This study explored to what extent international senior success can be predicted based on success that athletes achieved in either international junior level competitions (i.e. junior medalists) or senior competitions at a junior age (i.e. early achievers). The sample contains 4011 international male and female athletes from three combat sports (taekwondo, wrestling and boxing), who were born between 1974 and 1990 and participated in both international junior and senior-level competitions between 1990 and 2016. Gender and sport differences were compared. The results revealed that 61.4% of the junior medalists and 90.4% of the early achievers went on to win international medals at a senior age. Among the early achievers, 92.2% of the taekwondo athletes, 68.4% of the wrestling athletes and 37.9% of the boxing athletes could be reliably "predicted" to win international senior medals. The findings demonstrate that specific to the three combat sports examined, international junior success appears to be an important predictor to long-term international senior success.

International Heliophysical Year

NASA Technical Reports Server (NTRS)

Davila, Joseph, M.

2005-01-01

The International Heliophysical Year (IHY), an international program of scientific collaboration to understand the external drivers of planetary environments, will be conducted in 2007. This will be a major international event of great interest to the member States. The M Y will involve the deployment of new instrumentation, new observations from the ground and in space, and an education component. The IHY 2007 will coincide with the fiftieth anniversary of the International Geophysical Year (IGY) in 1957. The IGY was organized to study global phenomena of the Earth and Geospace involving about 60,000 scientists from 66 nations, working at thousands of stations, around the world to obtain simultaneous, global observations from the ground and space. Building on results obtained during IGY 1957, the IHY will expand to the study of universal processes in the solar system that affect the interplanetary and terrestrial environments. The study of energetic events in the solar system will pave the way for safe human space travel to the Moon and planets in the future, and it will serve to inspire the next generation of space physicists.

NASA International Environmental Partnerships

NASA Technical Reports Server (NTRS)

Lewis, Pattie; Valek, Susan

2010-01-01

For nearly five decades, the National Aeronautics and Space Administration (NASA) has been preeminent in space exploration. NASA has landed Americans on the moon, robotic rovers on Mars, and led cooperative scientific endeavors among nations aboard the International Space Station. But as Earth's population increases, the environment is subject to increasing challenges and requires more efficient use of resources. International partnerships give NASA the opportunity to share its scientific and engineering expertise. They also enable NASA to stay aware of continually changing international environmental regulations and global markets for materials that NASA uses to accomplish its mission. Through international partnerships, NASA and this nation have taken the opportunity to look globally for solutions to challenges we face here on Earth. Working with other nations provides NASA with collaborative opportunities with the global science/engineering community to explore ways in which to protect our natural resources, conserve energy, reduce the use of hazardous materials in space and earthly applications, and reduce greenhouse gases that potentially affect all of Earth's inhabitants. NASA is working with an ever-expanding list of international partners including the European Union, the European Space Agency and, especially, the nation of Portugal. Our common goal is to foster a sustainable future in which partners continue to explore the universe while protecting our home planet's resources for future generations. This brochure highlights past, current, and future initiatives in several important areas of international collaboration that can bring environmental, economic, and other benefits to NASA and the wider international space community.

Internal friction in enzyme reactions.

PubMed

Rauscher, Anna; Derényi, Imre; Gráf, László; Málnási-Csizmadia, András

2013-01-01

The empirical concept of internal friction was introduced 20 years ago. This review summarizes the results of experimental and theoretical studies that help to uncover the nature of internal friction. After the history of the concept, we describe the experimental challenges in measuring and interpreting internal friction based on the viscosity dependence of enzyme reactions. We also present speculations about the structural background of this viscosity dependence. Finally, some models about the relationship between the energy landscape and internal friction are outlined. Alternative concepts regarding the viscosity dependence of enzyme reactions are also discussed. Copyright © 2012 International Union of Biochemistry and Molecular Biology, Inc.

Strategic business planning for internal medicine.

PubMed

Ervin, F R

1996-07-01

The internal medicine generalist is at market risk with expansion of managed care. The cottage industry of Academic Departments of internal medicine should apply more business tools to the internal medicine business problem. A strength, weakness, opportunity, threat (SWOT) analysis demonstrates high vulnerability to the internal medicine generalist initiative. Recommitment to the professional values of internal medicine and enhanced focus on the master clinician as the competitive core competency of internal medicine will be necessary to retain image and market share.

BPPD Internal Application Checklists

EPA Pesticide Factsheets

EPA, Office of Pesticide Programs, BPPD internal application checklists for internal guidance to assist BPPD employees in their evaluation of applications submitted to BPPD by applicants and/or registrants.

Simulation in International Relations Education.

ERIC Educational Resources Information Center

Starkey, Brigid A.; Blake, Elizabeth L.

2001-01-01

Discusses the educational implications of simulations in international relations. Highlights include the development of international relations simulations; the role of technology; the International Communication and Negotiation Simulations (ICONS) project at the University of Maryland; evolving information technology; and simulating real-world…

Ozone-mist spray sterilization for pest control in agricultural management

NASA Astrophysics Data System (ADS)

Ebihara, Kenji; Mitsugi, Fumiaki; Ikegami, Tomoaki; Nakamura, Norihito; Hashimoto, Yukio; Yamashita, Yoshitaka; Baba, Seiji; Stryczewska, Henryka D.; Pawlat, Joanna; Teii, Shinriki; Sung, Ta-Lun

2013-02-01

We developed a portable ozone-mist sterilization system to exterminate pests (harmful insects) in agricultural field and greenhouse. The system is composed of an ozone generator, an ozone-mist spray and a small container of ozone gas. The ozone generator can supply highly concentrated ozone using the surface dielectric barrier discharge. Ozone-mist is produced using a developed nozzle system. We studied the effects of ozone-mist spray sterilization on insects and agricultural plants. The sterilization conditions are estimated by monitoring the behavior of aphids and observing the damage of the plants. It was shown that aphids were exterminated in 30 s without noticeable damages of the plant leaves. The reactive radicals with strong oxidation potential such as hydroxyl radical (*OH), hydroperoxide radical (*HO2), the superoxide ion radical (*O2‒) and ozonide radical ion (*O3‒) can increase the sterilization rate for aphids. Contribution to the Topical Issue "13th International Symposium on High Pressure Low Temperature Plasma Chemistry (Hakone XIII)", Edited by Nicolas Gherardi, Henryca Danuta Stryczewska and Yvan Ségui.

Synergies between human space exploration and science in the asteroid redirect mission and the potential Italian participation in the asteroid redirect robotic mission phase⋆

NASA Astrophysics Data System (ADS)

Tantardini, Marco; Flamini, Enrico

2017-07-01

In 2010, the study proposal called Asteroid Retrieval Mission (ARM) was selected by the Keck Institute for Space Studies (KISS) at the California Institute of Technology (Caltech). ARM had, as its main goal, the ambition to give a feasible, and realistic from a budget standpoint, destination to NASA Human Space Exploration (HSE) after the International Space Station (ISS), fulfilling President Obama's goal to have astronaut reach and interact with an asteroid (NEO) by 2025. ARM was formulated exploiting synergies between HSE and science, and with benefits also for technology development and in-space validation. In 2013, ARM, renamed Asteroid Redirect Mission, became a NASA program with the support of the White House. The Italian Space Agency (ASI) expressed interest to participate in the robotic phase of ARM, called Asteroid Redirect Robotic Mission (ARRM). This presentation, given at the XIII National (Italian) Congress of Planetary Sciences, had the goal to introduce ARM to the Italian scientific community to gather proposals for the possible Italian participation in NASA ARRM, such as ASI payloads that could be possibly hosted on NASA ARRM.

FRAX® International Task Force of the 2010 Joint International Society for Clinical Densitometry & International Osteoporosis Foundation Position Development Conference.

PubMed

Cauley, Jane A; El-Hajj Fuleihan, Ghada; Luckey, Marjorie M

2011-01-01

Osteoporosis is a serious worldwide epidemic. FRAX® is a web-based tool developed by the Sheffield WHO Collaborating Center team, that integrates clinical risk factors and femoral neck BMD and calculates the 10 year fracture probability in order to help health care professionals identify patients who need treatment. However, only 31 countries have a FRAX® calculator. In the absence of a FRAX® model for a particular country, it has been suggested to use a surrogate country for which the epidemiology of osteoporosis most closely approximates the index country. More specific recommendations for clinicians in these countries are not available. In North America, concerns have also been raised regarding the assumptions used to construct the US ethnic specific FRAX® calculators with respect to the correction factors applied to derive fracture probabilities in Blacks, Asians and Hispanics in comparison to Whites. In addition, questions were raised about calculating fracture risk in other ethnic groups e.g., Native Americans and First Canadians. The International Society for Clinical Densitometry (ISCD) in conjunction with the International Osteoporosis Foundation (IOF) assembled an international panel of experts that ultimately developed joint Official Positions of the ISCD and IOF advising clinicians regarding FRAX® usage. As part of the process, the charge of the FRAX® International Task Force was to review and synthesize data regarding geographic and race/ethnic variability in hip fractures, non-hip osteoporotic fractures, and make recommendations about the use of FRAX® in ethnic groups and countries without a FRAX® calculator. This synthesis was presented to the expert panel and constitutes the data on which the subsequent Official Positions are predicated. A summary of the International Task Force composition and charge is presented here. Copyright © 2011 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

Elite International Schools in the Global South: Transnational Space, Class Relationalities and the "Middling" International Schoolteacher

ERIC Educational Resources Information Center

Tarc, Paul; Mishra Tarc, Aparna

2015-01-01

The elite international school is a rich site for sociological inquiry in global times. In this paper, we conceptualize the international school as a transnational space of agonist social class-making given the dynamic positioning of the complement of international school actors. We position international schoolteachers in the middle of these…

International energy outlook, 2010

DOT National Transportation Integrated Search

2010-07-01

This report presents international energy projections through 2035, : prepared by the U.S. Energy Information Administration, including outlooks : for major energy fuels and associated carbon dioxide emissions. The International Energy Outlook 2010 (...

Internal Audit Manual.

DTIC Science & Technology

1985-11-01

multilocation audits because of the significant amount of planning, resources, and time they require, coordination of all review efforts shall be the...similar to the multilocation audits of the internal audit activities. f. The Military Department audit agencies and the Military Department criminal...34 -.° -.- . . °- . .. ?.. . .. . .. .. . .. . .. . .. . .. .. . .. . .. . .. .. . . .. :2 DOD 7600.7-M DEPARTMENT OF DEFENSE( %INTERNAL AUDIT ~MANUAL Jq- OFFICE OF L- INSPECTOR GENERAL

Internal Motion Estimation by Internal-external Motion Modeling for Lung Cancer Radiotherapy.

PubMed

Chen, Haibin; Zhong, Zichun; Yang, Yiwei; Chen, Jiawei; Zhou, Linghong; Zhen, Xin; Gu, Xuejun

2018-02-27

The aim of this study is to develop an internal-external correlation model for internal motion estimation for lung cancer radiotherapy. Deformation vector fields that characterize the internal-external motion are obtained by respectively registering the internal organ meshes and external surface meshes from the 4DCT images via a recently developed local topology preserved non-rigid point matching algorithm. A composite matrix is constructed by combing the estimated internal phasic DVFs with external phasic and directional DVFs. Principle component analysis is then applied to the composite matrix to extract principal motion characteristics, and generate model parameters to correlate the internal-external motion. The proposed model is evaluated on a 4D NURBS-based cardiac-torso (NCAT) synthetic phantom and 4DCT images from five lung cancer patients. For tumor tracking, the center of mass errors of the tracked tumor are 0.8(±0.5)mm/0.8(±0.4)mm for synthetic data, and 1.3(±1.0)mm/1.2(±1.2)mm for patient data in the intra-fraction/inter-fraction tracking, respectively. For lung tracking, the percent errors of the tracked contours are 0.06(±0.02)/0.07(±0.03) for synthetic data, and 0.06(±0.02)/0.06(±0.02) for patient data in the intra-fraction/inter-fraction tracking, respectively. The extensive validations have demonstrated the effectiveness and reliability of the proposed model in motion tracking for both the tumor and the lung in lung cancer radiotherapy.

77 FR 39560 - International Joint Commission

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-03

... DEPARTMENT OF STATE [Public Notice 7945] International Joint Commission International Joint Commission Invites Public Comment on Upper Great Lakes Report The International Joint Commission (IJC) announced today that it is inviting public comment on the final report of its International Upper Great...

International Education and (Dis)Embodied Cosmopolitanisms

ERIC Educational Resources Information Center

Sidhu, Ravinder Kaur; Dall'Alba, Gloria

2012-01-01

This article is a critical examination of practices and representations that constitute international education. While international education has provided substantial contributions and benefits for nation-states and international students, we question the discourses and practices which inform the international education export industry. The…

Project Management for International Development.

ERIC Educational Resources Information Center

Axelrod, Valija M.; Magisos, Joel H.

A project developed a content model for international project management training. It also compiled a bibliography of project management references, identified specific project management training needs based upon a survey of international sponsors and contractor personnel, and documented the training needs of international project managers. Data…

Language and the International Context

ERIC Educational Resources Information Center

Tonkin, Humphrey

1977-01-01

A discussion of the issue of unilinguism and linguistic pluralism on the international scene. The need for international communication where English is the dominant force and efforts to preserve cultural equality are seen as compelling reasons for promotion of an international language such as Esperanto. (AMH)

78 FR 18321 - International Code Council: The Update Process for the International Codes and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

... for Residential Construction in High Wind Regions. ICC 700: National Green Building Standard The..., coordinated, and necessary to regulate the built environment. Federal agencies frequently use these codes and... International Codes and Standards consist of the following: ICC Codes International Building Code. International...

75 FR 19944 - International Code Council: The Update Process for the International Codes and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-16

... for Residential Construction in High Wind Areas. ICC 700: National Green Building Standard. The... Codes and Standards that are comprehensive, coordinated, and necessary to regulate the built environment... International Codes and Standards consist of the following: ICC Codes International Building Code. International...

Interns_In_Their_Natural_Habitat

NASA Image and Video Library

2017-08-10

Discover internship opportunities at the NASA Johnson Space Center! This video shows some of the places interns work and some of the projects they contribute to. Interns work to make their mark and enjoy the entirety of the internship experience which includes touring laboratories and facilities, hearing lectures from astronauts and NASA’s leaders, participating in professional and social committees (like Video Committee) in spare time, and much more. Start your journey! For more on NASA internships: https://intern.nasa.gov/ https://nasajobs.nasa.gov/studentopps/default.htm For Johnson Space Center specific internships: https://pathways.jsc.nasa.gov/ https://www.nasa.gov/centers/johnson/education/interns/index.html --------------------------------- FOLLOW JOHNSON SPACE CENTER INTERNS! Facebook: @NASA.JSC.Students https://www.facebook.com/NASA.JSC.Students/ Instagram: @nasajscstudents https://www.instagram.com/nasajscstudents/ Twitter: @NASAJSCStudents https://twitter.com/nasajscstudents FOLLOW NASA INTERNS! Facebook: @NASAInterns https://www.facebook.com/NASAInterns/ Twitter: @NASAInterns https://twitter.com/nasainterns

Influence of drying time and temperature on bond strength of contemporary adhesives to dentine.

PubMed

Garcia, Fernanda C P; Almeida, Júlio C F; Osorio, Raquel; Carvalho, Ricardo M; Toledano, Manuel

2009-04-01

To evaluate the bond strength (microTBS) of self-etching adhesives in different solvent evaporation conditions. Flat dentine surfaces from extracted human third molars were bonded with: (1) 2 two-steps self-etching adhesives (Clearfil SE Bond-CSEB); (Protect Bond-PB) and (2) 2 one-step self-etch systems (Adper Prompt L Pop-ADPLP); (Xeno III-XIII). Bonded dentine surfaces were air-dried for 5s, 20s, 30s or 40s at either 21 degrees C or 38 degrees C. Composite build-ups were constructed incrementally. After storage in water for 24h at 37 degrees C, the specimens were prepared for microtensile bond strength testing. Data were analyzed by two-way ANOVA and Student-Newman-Keuls at alpha=0.05. CSEB and PB performed better at warm temperature with only 20s of air-blowing. The bond strength increased when XIII was performed at warm temperature at 40s air-blowing. Extended air-blowing not affect the performance of ADPLP, except at 30s air-blowing time at warm temperature. The use of a warm air-dry stream seems to be a clinical tool to improve the bond strength to self-etching adhesives.

The Cryogenic Near Infrared Spectropolarimeter for the Daniel K. Inouye Solar Telescope

NASA Astrophysics Data System (ADS)

Fehlmann, Andre; Giebink, Cindy; Kuhn, Jeffrey Richard; Mickey, D. L.; Scholl, Isabelle

2017-08-01

The Cryogenic Near Infrared Spectropolarimeter is one of the first light instruments for the Daniel K. Inouye Solar Telescope. This dual-beam instrument, which is currently characterized at the University of Hawaii’s Institute for Astronomy, is designed to sensitively measure the solar spectrum at wavelengths from 1 to 5 μm. The high dynamic range of the spectrograph and its context imager will provide sensitive data of the solar disk in the CO bands; unique observations of the low corona and unprecedented measurements of the coronal magnetic field. Observations near the limb and in the corona will greatly benefit from DKIST’s limb occulting system. The initial suite of filters includes selecting filters for the spectrograph at He I / Fe XIII 1080 nm, Si X 1430 nm, Si IX 3934 nm and CO 4651 nm as well as narrow band filters for the context imager at Fe XIII 1074.7 nm, He I 1083.0, Si X 1430.0 nm and J band 1250 nm. In this paper we will present an update on the ongoing instrument characterization and CryoNIRSP’s capabilities.

Do internal medicine interns practice etiquette-based communication? A critical look at the inpatient encounter.

PubMed

Block, Lauren; Hutzler, Lindsey; Habicht, Robert; Wu, Albert W; Desai, Sanjay V; Novello Silva, Kathryn; Niessen, Timothy; Oliver, Nora; Feldman, Leonard

2013-11-01

Etiquette-based communication may improve the inpatient experience but is not universally practiced. We sought to determine the extent to which internal medicine interns practice behaviors that characterize etiquette-based medicine. Trained observers evaluated the use of 5 key communication strategies by internal medicine interns during inpatient clinical encounters: introducing one's self, explaining one's role in the patient's care, touching the patient, asking open-ended questions, and sitting down with the patient. Participants at 1 site then completed a survey estimating how frequently they performed each of the observed behaviors. A convenience sample of 29 interns was observed on a total of 732 patient encounters. Overall, interns introduced themselves 40% of the time and explained their role 37% of the time. Interns touched patients on 65% of visits, asked open-ended questions on 75% of visits, and sat down with patients during 9% of visits. Interns at 1 site estimated introducing themselves and their role and sitting with patients significantly more frequently than was observed (80% vs 40%, P < 0.01; 80% vs 37%, P < 0.01; and 58% vs 9%, P < 0.01, respectively). Resident physicians introduced themselves to patients, explained their role, and sat down with patients infrequently during observed inpatient encounters. Residents surveyed tended to overestimate their own practice of etiquette-based medicine. © 2013 Society of Hospital Medicine.

International Space Station (ISS)

NASA Image and Video Library

1994-09-21

Artist's concept of the final configuration of the International Space Station (ISS) Alpha. The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide an unprecedented undertaking in scientific, technological, and international experimentation.

International Space Station (ISS)

NASA Image and Video Library

1994-04-20

An artist's concept of a fully deployed International Space Station (ISS) Alpha. The ISS-A is a multidisciplinary laboratory, technology test bed, and observatory that will provide an unprecedented undertaking in scientific, technological, and international experiments.

International energy outlook, 2000

DOT National Transportation Integrated Search

2000-03-01

The International Energy Outlook 2000 (IEO2000) presents : an assessment by the Energy Information Administration : (EIA) of the outlook for international energy : markets through 2020. The report is an extension of the : EIAs Annual Energy Outloo...

Birds of a Feather: Senior International Baccalaureate International Schools Leadership in Service

ERIC Educational Resources Information Center

Gardner-McTaggart, Alexander

2018-01-01

This article presents original research into International Baccalaureate international schools' directors in Western Europe, based on multiphase contact with six director participants over two years and employing an aspect of critical-phenomenology. Successful leadership in this context responds to market demands with a commodification of Anglo…

International Opportunities and Programs at NSF

NASA Astrophysics Data System (ADS)

Wodarczyk, F.

2006-05-01

The National Science Foundation's Office of International Science and Engineering (OISE) promotes the development of an integrated, Foundation-wide international strategy for international science and engineering activities both inside and outside NSF and manages international programs that are innovative, catalytic, and responsive to a broad range of NSF interests. Specifically, OISE supports programs to expand and enhance leading-edge international research and education opportunities for U.S. scientists and engineers, especially at the early career stage. It works to build and strengthen effective institutional partnerships throughout the global science and engineering research and education community, and it supports international collaborations in NSF's priority research areas. This talk will highlight opportunities for international collaboration for individuals at all levels of their careers, from student to established researcher, with examples of supported programs. Some recent activities focus on bringing together researchers in scientific disciplines and experts in cyberinfrastructure to promote and enable international data collection, manipulation, storage, and sharing via high-speed networks.

New International School Library Guidelines

ERIC Educational Resources Information Center

Oberg, Dianne

2018-01-01

The publication in 2015 of new international school library guidelines was the culmination of a two-year process involving a wide network of contributors. The process was guided by the Joint Committee of the International Federation of Library Associations (IFLA) School Libraries Section and the International Association of School Librarianship…

International images: business cards.

PubMed

Gaston, S; Pucci, J

1991-01-01

Nursing specialists engage in a variety of international professional activities. Business cards are an important aspect of establishing a professional image. This article presents recommended business card contents, international etiquette, card design and production, and cared innovations.

12 CFR 618.8430 - Internal controls.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Internal controls. 618.8430 Section 618.8430 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM GENERAL PROVISIONS Internal Controls § 618.8430 Internal controls. Each Farm Credit institution's board of directors must adopt an internal...

12 CFR 618.8430 - Internal controls.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Internal controls. 618.8430 Section 618.8430 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM GENERAL PROVISIONS Internal Controls § 618.8430 Internal controls. Each Farm Credit institution's board of directors must adopt an internal...

12 CFR 618.8430 - Internal controls.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Internal controls. 618.8430 Section 618.8430 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM GENERAL PROVISIONS Internal Controls § 618.8430 Internal controls. Each Farm Credit institution's board of directors must adopt an internal...

12 CFR 618.8430 - Internal controls.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Internal controls. 618.8430 Section 618.8430 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM GENERAL PROVISIONS Internal Controls § 618.8430 Internal controls. Each Farm Credit institution's board of directors must adopt an internal...

Learning in and from the West: International Students and International Women's Organisations in the Interwar Period

ERIC Educational Resources Information Center

Sandell, Marie

2015-01-01

This article explores the importance of higher education to international women's organisations such as the International Federation of University Women, the International Council of Women, the International Alliance of Women and Women's International League for Peace and Freedom, and asks how studying abroad contributed to the…

International law and communicable diseases.

PubMed Central

Aginam, Obijiofor

2002-01-01

Historically, international law has played a key role in global communicable disease surveillance. Throughout the nineteenth century, international law played a dominant role in harmonizing the inconsistent national quarantine regulations of European nation-states; facilitating the exchange of epidemiological information on infectious diseases; establishing international health organizations; and standardization of surveillance. Today, communicable diseases have continued to re-shape the boundaries of global health governance through legally binding and "soft-law" regimes negotiated and adopted within the mandate of multilateral institutions - the World Health Organization, the World Trade Organization, the Food and Agriculture Organization, and the Office International des Epizooties. The globalization of public health has employed international law as an indispensable tool in global health governance aimed at diminishing human vulnerability to the mortality and morbidity burdens of communicable diseases. PMID:12571722

50 years of Arabidopsis research: highlights and future directions.

PubMed

Provart, Nicholas J; Alonso, Jose; Assmann, Sarah M; Bergmann, Dominique; Brady, Siobhan M; Brkljacic, Jelena; Browse, John; Chapple, Clint; Colot, Vincent; Cutler, Sean; Dangl, Jeff; Ehrhardt, David; Friesner, Joanna D; Frommer, Wolf B; Grotewold, Erich; Meyerowitz, Elliot; Nemhauser, Jennifer; Nordborg, Magnus; Pikaard, Craig; Shanklin, John; Somerville, Chris; Stitt, Mark; Torii, Keiko U; Waese, Jamie; Wagner, Doris; McCourt, Peter

2016-02-01

922 I. 922 II. 922 III. 925 IV. 925 V. 926 VI. 927 VII. 928 VIII. 929 IX. 930 X. 931 XI. 932 XII. 933 XIII. Natural variation and genome-wide association studies 934 XIV. 934 XV. 935 XVI. 936 XVII. 937 937 References 937 SUMMARY: The year 2014 marked the 25(th) International Conference on Arabidopsis Research. In the 50 yr since the first International Conference on Arabidopsis Research, held in 1965 in Göttingen, Germany, > 54 000 papers that mention Arabidopsis thaliana in the title, abstract or keywords have been published. We present herein a citational network analysis of these papers, and touch on some of the important discoveries in plant biology that have been made in this powerful model system, and highlight how these discoveries have then had an impact in crop species. We also look to the future, highlighting some outstanding questions that can be readily addressed in Arabidopsis. Topics that are discussed include Arabidopsis reverse genetic resources, stock centers, databases and online tools, cell biology, development, hormones, plant immunity, signaling in response to abiotic stress, transporters, biosynthesis of cells walls and macromolecules such as starch and lipids, epigenetics and epigenomics, genome-wide association studies and natural variation, gene regulatory networks, modeling and systems biology, and synthetic biology. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

Setting Priorities in Global Child Health Research Investments: Guidelines for Implementation of the CHNRI Method

PubMed Central

Rudan, Igor; Gibson, Jennifer L.; Ameratunga, Shanthi; El Arifeen, Shams; Bhutta, Zulfiqar A.; Black, Maureen; Black, Robert E.; Brown, Kenneth H.; Campbell, Harry; Carneiro, Ilona; Chan, Kit Yee; Chandramohan, Daniel; Chopra, Mickey; Cousens, Simon; Darmstadt, Gary L.; Gardner, Julie Meeks; Hess, Sonja Y.; Hyder, Adnan A.; Kapiriri, Lydia; Kosek, Margaret; Lanata, Claudio F.; Lansang, Mary Ann; Lawn, Joy; Tomlinson, Mark; Tsai, Alexander C.; Webster, Jayne

2008-01-01

This article provides detailed guidelines for the implementation of systematic method for setting priorities in health research investments that was recently developed by Child Health and Nutrition Research Initiative (CHNRI). The target audience for the proposed method are international agencies, large research funding donors, and national governments and policy-makers. The process has the following steps: (i) selecting the managers of the process; (ii) specifying the context and risk management preferences; (iii) discussing criteria for setting health research priorities; (iv) choosing a limited set of the most useful and important criteria; (v) developing means to assess the likelihood that proposed health research options will satisfy the selected criteria; (vi) systematic listing of a large number of proposed health research options; (vii) pre-scoring check of all competing health research options; (viii) scoring of health research options using the chosen set of criteria; (ix) calculating intermediate scores for each health research option; (x) obtaining further input from the stakeholders; (xi) adjusting intermediate scores taking into account the values of stakeholders; (xii) calculating overall priority scores and assigning ranks; (xiii) performing an analysis of agreement between the scorers; (xiv) linking computed research priority scores with investment decisions; (xv) feedback and revision. The CHNRI method is a flexible process that enables prioritizing health research investments at any level: institutional, regional, national, international, or global. PMID:19090596

International cooperation in water resources

USGS Publications Warehouse

Jones, J.R.; Beall, R.M.; Giusti, E.V.

1979-01-01

Advancements in hydrology proceeded slowly until the late 1800's when new ventures created a surge of interest and accomplishment. Progress waned again until the middle 20th century when an International Hydrological Decade was conceived, eventually receiving wide multinational support from governmental agencies and nongovernmental institutions. Organized by UNESCO, the Decade program was launched January 1, 1965. Participation included 107 nations, six United Nations agencies, and more than a dozen international scientific organizations. The initial program emphasized scientific research, and international cooperation; the second half of the Decade, emphasized technical assistance and technology transfer, largerly through education, training and demonstration. The success of the Decade led to the establishment of the International Hydrological Program, again under the aegis of UNESCO, to continue the work of the Decade indefinitely. The five major program activities, now involving about 90 countries and several international organizations, include: the scientific program, the promotion of education and training, the enhancement of information exchange, support of technical assistance, and the enlargement of regional cooperation. A significant amount of activity related to hydrological data networks and forecasting is carried on in an Operational Hydrology Programme by the WMO, chiefly through its Commission for Hydrology. Other international governmental organizations with a strong interest in water include the UN, the UN Development Programme, the FAO, the WHO, the International Atomic Energy Agency, the UN Environment Programme, the International Standardization Organization, and developmental institutions such as the World Bank. The specialized interests of researchers outside of the governmental structure, are met through association in various scientific and technical organizations which are world wide in scope and membership. Notwithstanding a sometimes

Improving International Assessment through Evaluation

ERIC Educational Resources Information Center

Rutkowski, David

2018-01-01

In this article I advocate for a new discussion in the field of international large-scale assessments; one that calls for a reexamination of international large-scale assessments (ILSAs) and their use. Expanding on the high-quality work in this special issue I focus on three inherent limitations to international large-scale assessments noted by…

International Cancer Screening Network

Cancer.gov

The International Cancer Screening Network promotes evidence-based cancer screening implementation and evaluation with cooperation from multilateral organizations around the globe. Learn more about how ICSN aims to reduce the global burden of cancer by supporting research and international collaboration.

International Space Station (ISS)

NASA Image and Video Library

1995-04-17

International Cooperation Phase III: A Space Shuttle docked to the International Space Station (ISS) in this computer generated representation of the ISS in its completed and fully operational state with elements from the U.S., Europe, Canada, Japan, and Russia.

Internal shim

DOEpatents

Barth, Clyde H.; Blizinski, Theodore W.

2003-05-13

An internal shim used to accurately measure spaces in conjunction with a standard small probe has a shim top and a chassis. The internal shim is adjustably fixed within the space to be measured using grippers that emerge from the chassis and which are controlled by an arm pivotably attached to the shim top. A standard small probe passes through the shim along guides on the chassis and measures the distance between the exterior of the chassis and the boundary. By summing the measurements on each side of the chassis and the width of the chassis, the dimension of the space can be determined to within 0.001 inches.

The Federal Role in Improving Elementary and Secondary Education

DTIC Science & Technology

1993-05-01

programs of teacher educa- to consider the desirability and feasibility of S. ,,,,,,, ,,,,,, ,, .,. . , .,.. . SUMMARY Xiii national academic standards and...of a volun- ceived increased scrutiny during the 1980s be- tary system of assessments to measure the cause many people believed that the academic ...critics charging that they attain, as measured by standardized tests of have little empirical validity, that they may academic knowledge. These outcomes

Macroeconomic Consequences of Job Discrimination Against Women in Russia

DTIC Science & Technology

2010-06-01

operator engaged in hot dismantling of resistance furnaces in the production of abrasives 208. Caster of abrasive materials 209. Furnace bottom...are the first fired .125 Additionally, despite more education than their male counterparts, women stay unemployed twice as long as men.126 As a result...and networks (Nos. 204-205) XII. Production of abrasives (Nos. 206-210) XIII. Electrical-engineering production (Nos. 211-219) XIV. Radio

Design and Implementation of a Motor Incremental Shaft Encoder

DTIC Science & Technology

2008-09-01

SDC Student Design Center VHDL Verilog Hardware Description Language VSC Voltage Source Converters ZCE Zero Crossing Event xiii EXECUTIVE...student to make accurate predictions of voltage source converters ( VSC ) behavior via software simulation; these simulated results could also be... VSC ), and several other off-the-shelf components, a circuit board interface between FPGA and the power source, and a desktop computer [1]. Now, the

Development of Methodology and Technology for Identifying and Quantifying Emission Products from Open Burning and Open Detonation Thermal Treatment Methods. Bangbox Test Series. Volume 2. Test Development

DTIC Science & Technology

1992-01-01

Calculated by the Carbon Balance and by the C -V M ethod . ...................................... ... ... ... ... ... 6-8 x I I Table 6.3 EF for the...A-i APPENDIX B. SAMPLING AND DETERMINATION OF POLYCHLORINATED DIBENZODIOXINS AND DIBENZOFURANS ................. B-13 APPENDIX C . DISTRIBUTION... C -I I I I I I I I I I I I I I xiii I INTENTIONALLY BLANK xiv --I IACKNOWLEDGEMENTS I The following

Application of the Sterility Principle for Tsetse Fly Eradication or Control. Revision.

DTIC Science & Technology

1981-08-14

1977. Digestive processes of haematophagous insects . XIII. Evidence for the digestive function of midgut proleinases in Glossina morsitans morsitans...FOOD AND AGRICULTURAL DEVELOPMENT ABSTRACT This review deals with the conditions required for the successful application of the sterile insect ...numbers of sterile male insects are released into a wild population so that they can disperse and compete with the fertile males of the natural population

Department of Defense Small Business (SB) Program: A Knowledge-Level Analysis of How Customer Education Relates to Meeting SB Goals

DTIC Science & Technology

2014-12-01

xiii SB small business SBA Small Business Administration SBP small business program SBS small business specialist SDB small disadvantaged business...government contracts. 2. Small Disadvantaged Business The purpose of the Small Disadvantaged Business ( SDB ) program is to increase opportunities for...socially and economically disadvantaged businesses to compete for contract awards. A SDB is “a small business that is at least 51 percent owned by one

An Adaptive, Multi-Rate Linear Quadratic Regulator for a Shipboard MVDC Distribution System with Constant Power Loads

DTIC Science & Technology

2017-09-01

12. xii THIS PAGE INTENTIONALLY LEFT BLANK xiii LIST OF ACRONYMS AND ABBREVIATIONS AC alternating current ATG auxiliary turbine generator...invariant MTG main turbine generator MVDC medium voltage DC NAVSEA U.S. Naval Sea Systems Command PGM power generation module RC resistor-capacitor RL...arrangement because the gas turbines used for prime movers are more efficient when they are fully loaded. By amalgamating loads onto fewer machines

Rapid Training of Information Extraction with Local and Global Data Views

DTIC Science & Technology

2012-05-01

56 xiii 4.1 An example of words and their bit string representations. Bold ones are transliterated Arabic words...Natural Language Processing ( NLP ) community faces new tasks and new domains all the time. Without enough labeled data of a new task or a new domain to...conduct supervised learning, semi-supervised learning is particularly attractive to NLP researchers since it only requires a handful of labeled examples

Report of the Admission of Women to the U.S. Military Academy (Project Athena III)

DTIC Science & Technology

1979-06-01

Attitudes Toward Women’s Roles. ..... 47 Summary ..... ............ . . . . 52 CHAPTER 2 CADET BASIC TRAINING ........ 54 Male and Female Performances...Sex for West Point Cadets .......... ... 46 17. Comparison of Attitude Toward Wbmen Scores WANS) for Men and Women at Several Institutions...gender. xiii S . . ... , , , , " .... i • :•: - :• Although attitudes toward womens’ roles in society and in the military are more traditional for men

Analysis of Selected Enhancements for Soil Vapor Extraction

DTIC Science & Technology

1997-09-01

Inches per second ACRONYMS AND ABBREVIATIONS (Continued) xiii ISB In situ bioremediation JFK John F. Kennedy Airport K Hydraulic conductivity KAI KAI...wells by an applied vacuum. RFH is effective for treating VOCs in low-permeability soil in the vadose zone. Electrical Resistance Heating : This... applied vacuum. However, application of steam injection/stripping systems is limited to medium- to high-permeability soils. ER heating is more

Challenges to Military Operations in Support of U.S. Interests. Volume 2: Main Report

DTIC Science & Technology

2008-12-01

Challenges to Military Operations in Support of U.S. Interests U.S. conventional military capability remains unmatched by any state. As a result, nations...greater importance. PR EF AC E I xiii Preface U.S. conventional military capability remains unmatched by any state. U.S...scope of the study remained robust, presenting the challenge of how to approach the investigation into U.S. capabilities, capability gaps, and

12 CFR 618.8430 - Internal controls.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Internal controls. 618.8430 Section 618.8430 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM GENERAL PROVISIONS Internal Controls § 618.8430 Internal controls. Each Farm Credit institution's board of directors must adopt an internal control policy, providing adequate direction to...

International Education, Values and Attitudes: A Critical Analysis of the International Baccalaureate (IB) Learner Profile

ERIC Educational Resources Information Center

Wells, John

2011-01-01

This article provides a critical review of the way that the International Baccalaureate (IB) promotes international education and international mindedness through the IB Learner Profile. While discussing theories of values and attitudes, and the teaching of values and theories of value acquisition, the paucity of such topics in IB texts is noted.…

Intersectionality of internalized HIV stigma and internalized substance use stigma: Implications for depressive symptoms

PubMed Central

Earnshaw, Valerie A; Smith, Laramie R; Cunningham, Chinazo O; Copenhaver, Michael M

2016-01-01

We adopted an intersectionality framework and examined whether the relationship between internalized HIV stigma and depressive symptoms is moderated by internalized substance use stigma. A total of 85 people living with HIV with a history of substance use in the Bronx, New York, completed a survey. Results revealed evidence of moderation: Participants who internalized HIV stigma experienced greater depressive symptoms only if they also internalized substance use stigma. Researchers should examine stigma associated with multiple socially devalued characteristics to best understand how stigma impacts mental health among people living with HIV. Healthcare providers should address stigma associated with the full range of socially devalued characteristics with which people living with HIV live. PMID:24170015

Intersectionality of internalized HIV stigma and internalized substance use stigma: Implications for depressive symptoms.

PubMed

Earnshaw, Valerie A; Smith, Laramie R; Cunningham, Chinazo O; Copenhaver, Michael M

2015-08-01

We adopted an intersectionality framework and examined whether the relationship between internalized HIV stigma and depressive symptoms is moderated by internalized substance use stigma. A total of 85 people living with HIV with a history of substance use in the Bronx, New York, completed a survey. Results revealed evidence of moderation: Participants who internalized HIV stigma experienced greater depressive symptoms only if they also internalized substance use stigma. Researchers should examine stigma associated with multiple socially devalued characteristics to best understand how stigma impacts mental health among people living with HIV. Healthcare providers should address stigma associated with the full range of socially devalued characteristics with which people living with HIV live. © The Author(s) 2013.

International. [SITE 2002 Section].

ERIC Educational Resources Information Center

Willis, Dee Anna, Ed.

This document contains the following papers on international issues from the SITE (Society for Information Technology & Teacher Education) 2002 conference: (1) "The Management of Technological Change within Faculties in International American Schools" (Martine Audeoud); (2) "Going Global: Using a Website Development Project To…

Migration in far west Nepal: intergenerational linkages between internal and international migration of rural-to-urban migrants.

PubMed

Poertner, Ephraim; Junginger, Mathias; Müller-Böker, Ulrike

2011-01-01

In Nepal, international labor migration to India and overseas, as well as internal migration to the rural Nepalese lowlands, is of high socioeconomic significance. Scholarly debates about migration in Nepal have gradually shifted from an economic to a more holistic perspective, also incorporating social dimensions. However, little evidence has been generated about internal migration to urban destinations and the potential linkages between international and internal migration. This article draws on Bourdieu's “Theory of Practice” and sees migration as a social practice. Accordingly, migration practice is regarded as a strategy social agents apply to increase or transfer capitals and ultimately secure or improve their social position. Evidence for this argument is based on a qualitative case study of rural to urban migrants in Far West Nepal conducted in July and August 2009. The study at hand addresses linkages between internal and international migration practices and provides insight about a social stratum that is often neglected in migration research: the middle class and, more precisely, government employees. The authors show that social relations are crucial for channeling internal migration to a specific destination. Furthermore, they unveil how internal migration is connected to the international labor migration of former generations. Finally, the authors examine how migration strategies adopted over generations create multi-local social networks rooted in the family's place of origin.

Impacts of Culture on International Negotiations

NASA Astrophysics Data System (ADS)

Goodin, James Ronald

2010-09-01

This paper provides practical suggestions for developing a healthy and complete working relationship between the system safety practitioner and international business partners, international vendors and international customers.

International Perspectives on General Internal Medicine and the Case for “Globalization” of a Discipline

PubMed Central

Ghali, William A; Greenberg, Peter B; Mejia, Raul; Otaki, Junji; Cornuz, Jacques

2006-01-01

General internal medicine (GIM) has flourished in the United States (U.S.). Unlike other subspecialties of internal medicine, however, GIM's evolution has not been global in scope, but rather appears to have occurred in isolation within countries. Here, we describe international models of GIM from Canada, Switzerland, Australia/New Zealand, Argentina, and Japan, and compare these with the U.S. model. There are notable differences in the typical clinical roles assumed by General Internists across these 7 countries, but also important overlap in clinical and academic domains. Despite this overlap, there has been a relative lack of contact among General Internists from these and other countries at a truly international GIM meeting; the time is now for increased international exchange and the “globalization” of GIM. PMID:16336623

Putting 'international' back in IPEC.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veil, J. A.

During the previous six annual sessions of the International Petroleum Environmental Conference (IPEC), little attention has been given to international issues. Although the US is clearly a leader in oil field research and regulatory development information is available on interesting projects throughout the world Many participants in IPEC have little exposure to international oil and gas environmental problems and solutions. Beginning with the 7th IPEC, a stronger effort is being made to include international issues in the confidence. This paper describes some of the author's experiences in working with international oil and gas environmental issues in North America, Latin America,more » Europe, and Asia. Among the topics to be discussed are the issues that developing oil and gas-producing nations face and the need for sensitivity to other nation's cultures and legal systems.« less

History of the international societies in health technology assessment: International Society for Technology Assessment in Health Care and Health Technology Assessment International.

PubMed

Banta, David; Jonsson, Egon; Childs, Paul

2009-07-01

The International Society for Technology Assessment in Health Care (ISTAHC) was formed in 1985. It grew out of the increasing awareness of the international dimensions of health technology assessment (HTA) and the need for new communication methods at the international level. The main function of ISTAHC was to present an annual conference, which gradually grew in size, and also to generally improve in quality from to year. ISTAHC overextended itself financially early in the first decade of the 2000s and had to cease its existence. A new society, Health Technology Assessment international (HTAi), based on many of the same ideas and people, grew up beginning in the year 2003. The two societies have played a large role in making the field of HTA visible to people around the world and providing a forum for discussion on the methods and role of HTA.

Tabulation of comet observations.

NASA Astrophysics Data System (ADS)

1993-01-01

Concerning comets: 1973 XII Kohoutek, 1975 IX Kobayashi-Berger-Milon, 1976 VI West, 1976 XI P/d'Arrest, 1977 XIV Kohler, 1979 X Bradfield, 1980 X P/Stephan-Oterma, 1980 XV Bradfield, 1981 II Panther, 1982 VI Austin, 1983 V Sugano-Saigusa-Fujikawa, 1983 VII IRAS-Araki-Alcock, 1983 XIII P/Kopff, 1984 XIII Austin, 1984 XXIII Levy-Rudenko, 1985 XIII P/Giacobini-Zinner, 1985 XVII Hartley-Good, 1985 XIX Thiele, 1986 I P/Boethin, 1986 III P/Halley, 1986 XVIII Terasako, 1987 II Sorrells, 1987 III Nishikawa-Takamizawa-Tago, 1987 X P/Grigg-Skjellerup, 1987 XXIII Rudenko, 1987 XXIX Bradfield, 1987 XXXII McNaught, 1987 XXXIII P/Borrelly, 1988 IV Furuyama, 1988 V Liller, 1988 XIV P/Tempel 2, 1988 XV Machholz, 1988 XX Yanaka, 1988 XXIV Yanaka, 1989 X P/Brorsen-Metcalf, 1989 XV P/Schwassmann-Wachmann 1, 1989 XIX Okazaki-Levy-Rudenko, 1989 XXI Helin-Roman-Alu, 1989 XXII Aarseth-Brewington, 1990 III Černis-Kiuchi-Nakamura, 1990 VI Skorichenko-George, 1990 VIII P/Schwassmann-Wachmann 3, 1990 IX P/Peters-Hartley, 1990 X P/Wild 4, 1990 XIV P/Honda Mrkos-Pajdušáková, 1990 XVII Tsuchiya-Kiuchi, 1990 XXI P/Encke, 1990 XXVI Arai, 1991 XI P/Levy, 1991 XV P/Hartley 2, 1991 XVI P/Wirtanen, 1991 XVII P/Arend-Rigaux, 1991 XXI P/Faye, 1991 XXIII P/Shoemaker 1, 1991 XXIV Shoemaker-Levy, 1991l Helin-Lawrence, 1991ο P/Chernykh, 1991r Helin-Alu, 1991a1 Shoemaker-Levy, 1991g1 Zanotta-Brewington, 1991h1 Mueller, 1912d Tanaka-Machholz, 1992f P/Shoemaker-Levy 8, 1992k Machholz, 1992l P/Giclas, 1992p P/Brewington, 1992q Helin-Lawrence, 1992s P/Ciffréo, 1992t P/Swift-Tuttle, 1992u P/Väisälä, 1992x P/Schaumasse, 1992y Shoemaker, 1992a1 Ohshita, 1993a Mueller, P/Smirnova-Chernykh.

The brain commission of the international association of academies: the first international society of neurosciences.

PubMed

Richter, J

2000-08-01

International associations of scientists, set up to organize cooperative scientific investigations in an international scope and to lay down global binding standards of research, are of great and still growing importance for the advancement of science. This was also recognized at the beginning of the 20th century by the community of researchers in basic and clinical neurological sciences, who created their first international organization following the trend initiated by scholars in astronomy and geophysics. Thus, the so-called "Brain Commission" of the International Association of Academies was founded in 1903 and was active until the outbreak of the First World War. The Brain Commission had no successor for nearly half a century, until the "International Brain Research Organization" (IBRO) was founded in 1961. Although the Brain Commission could exert an impact on neurosciences only for one decade, this international scientific association inspired and promoted the foundation of a series of Brain Research Institutes, which in part still exist in Europe, and long-lasting innovations in the neurosciences.

Internal-illumination photoacoustic computed tomography

NASA Astrophysics Data System (ADS)

Li, Mucong; Lan, Bangxin; Liu, Wei; Xia, Jun; Yao, Junjie

2018-03-01

We report a photoacoustic computed tomography (PACT) system using a customized optical fiber with a cylindrical diffuser to internally illuminate deep targets. The traditional external light illumination in PACT usually limits the penetration depth to a few centimeters from the tissue surface, mainly due to strong optical attenuation along the light propagation path from the outside in. By contrast, internal light illumination, with external ultrasound detection, can potentially detect much deeper targets. Different from previous internal illumination PACT implementations using forward-looking optical fibers, our internal-illumination PACT system uses a customized optical fiber with a 3-cm-long conoid needle diffuser attached to the fiber tip, which can homogeneously illuminate the surrounding space and substantially enlarge the field of view. We characterized the internal illumination distribution and PACT system performance. We performed tissue phantom and in vivo animal studies to further demonstrate the superior imaging depth using internal illumination over external illumination. We imaged a 7.5-cm-deep leaf target embedded in optically scattering medium and the beating heart of a mouse overlaid with 3.7-cm-thick chicken tissue. Our results have collectively demonstrated that the internal light illumination combined with external ultrasound detection might be a useful strategy to improve the penetration depth of PACT in imaging deep organs of large animals and humans.

[Decision procedures and international law].

PubMed

Mahiou, A

1992-01-01

This work examines the significance of international spaces in the ocean, the polar regions, the air, and beyond the atmosphere; the importance of their resources; and the prospects for communal management of them in the future. International spaces and resources are considered those over which 1 country cannot exercise any right of appropriation and over which all countries exercise exactly the same rights. International spaces are more extensive than national spaces, and their extension and potential richness of resources incite nations to attempt to exercise control over them. Concerns about the environment have contributed to development of the notion of a common patrimony of humanity and the consequent rejection of traditional concepts of total freedom of action of states in regard to common spaces and resources. The existing governance of international spaces and resources was guided by a few simple principles that assured free access, with only the problems of harmonizing the uses and interests of the concerned countries. The idea of a common patrimony of humanity is closely linked to development of the law of the sea, in which it received its most complete expression to date. The emergence and recognition of juridical principles relative to common spaces and resources has been a long and controversial process, and not all such principles have attracted the same degree of support among nations. Even when consensus has been achieved regarding 1 of the principles, divergent interpretations have been made concerning the content and scope of the principle or the regulations that should result from it. 6 principles can be identified concerning nonappropriation, the oldest and long the only principle regulating use of international spaces; peaceful utilization; rational utilization; equitable utilization; protection of spaces and resources; and joint international administration or management. An important question concerning the development of a structure for

Educational Administration: International Movement.

ERIC Educational Resources Information Center

Stone, Franklin D.

1978-01-01

The field of educational administration is achieving the status of an international movement. Although most voluntary educational administration organizations are not international, the exceptions are the University Council for Educational Administration (UCEA) and the Commonwealth Council for Educational Administration (CCEA). The UCEA was formed…

Internal waves, Andaman Sea

NASA Image and Video Library

1994-09-30

STS068-236-044 (30 September-11 October 1994) --- These internal waves in the Andaman Sea, west of Burma, were photographed from 115 nautical miles above Earth by the crew of the Space Shuttle Endeavour during the Space Radar Laboratory 2 (SRL-2) mission. The internal waves smooth out some of the capillary waves at the surface in bands and travel along the density discontinuity at the bottom of the mixed layer depth. There is little evidence of the internal waves at the surface. They are visible in the Space Shuttle photography because of sunglint, which reflects off the water.

Beyond health aid: would an international equalization scheme for universal health coverage serve the international collective interest?

PubMed Central

2014-01-01

It has been argued that the international community is moving ‘beyond aid’. International co-financing in the international collective interest is expected to replace altruistically motivated foreign aid. The World Health Organization promotes ‘universal health coverage’ as the overarching health goal for the next phase of the Millennium Development Goals. In order to provide a basic level of health care coverage, at least some countries will need foreign aid for decades to come. If international co-financing of global public goods is replacing foreign aid, is universal health coverage a hopeless endeavor? Or would universal health coverage somehow serve the international collective interest? Using the Sustainable Development Solutions Network proposal to finance universal health coverage as a test case, we examined the hypothesis that national social policies face the threat of a ‘race to the bottom’ due to global economic integration and that this threat could be mitigated through international social protection policies that include international cross-subsidies – a kind of ‘equalization’ at the international level. The evidence for the race to the bottom theory is inconclusive. We seem to be witnessing a ‘convergence to the middle’. However, the ‘middle’ where ‘convergence’ of national social policies is likely to occur may not be high enough to keep income inequality in check. The implementation of the international equalization scheme proposed by the Sustainable Development Solutions Network would allow to ensure universal health coverage at a cost of US$55 in low income countries-the minimum cost estimated by the World Health Organization. The domestic efforts expected from low and middle countries are far more substantial than the international co-financing efforts expected from high income countries. This would contribute to ‘convergence’ of national social policies at a higher level. We therefore submit that the proposed

The International Reference Ionosphere 2012 - a model of international collaboration

NASA Astrophysics Data System (ADS)

Bilitza, Dieter; Altadill, David; Zhang, Yongliang; Mertens, Chris; Truhlik, Vladimir; Richards, Phil; McKinnell, Lee-Anne; Reinisch, Bodo

2014-02-01

The International Reference Ionosphere (IRI) project was established jointly by the Committee on Space Research (COSPAR) and the International Union of Radio Science (URSI) in the late sixties with the goal to develop an international standard for the specification of plasma parameters in the Earth's ionosphere. COSPAR needed such a specification for the evaluation of environmental effects on spacecraft and experiments in space, and URSI for radiowave propagation studies and applications. At the request of COSPAR and URSI, IRI was developed as a data-based model to avoid the uncertainty of theory-based models which are only as good as the evolving theoretical understanding. Being based on most of the available and reliable observations of the ionospheric plasma from the ground and from space, IRI describes monthly averages of electron density, electron temperature, ion temperature, ion composition, and several additional parameters in the altitude range from 60 km to 2000 km. A working group of about 50 international ionospheric experts is in charge of developing and improving the IRI model. Over time as new data became available and new modeling techniques emerged, steadily improved editions of the IRI model have been published. This paper gives a brief history of the IRI project and describes the latest version of the model, IRI-2012. It also briefly discusses efforts to develop a real-time IRI model. The IRI homepage is at http://IRImodel.org.

15 CFR 740.11 - Governments, international organizations, and international inspections under the Chemical...

Code of Federal Regulations, 2010 CFR

2010-01-01

... use. The IAEA is an international organization that establishes and administers safeguards designed to.... Euratom establishes and administers safeguards designed to ensure that special nuclear materials and other... or Euratom international safeguards use provided that IAEA or Euratom maintains control of or...

The Evolution of General Internal Medicine (GIM)in Canada: International Implications.

PubMed

Card, Sharon E; Clark, Heather D; Elizov, Michelle; Kassam, Narmin

2017-05-01

General internal medicine (GIM), like other generalist specialties, has struggled to maintain its identity in the face of mounting sub-specialization over the past few decades. In Canada, the path to licensure for general internists has been through the completion of an extra year of training after three core years of internal medicine. Until very recently, the Royal College of Physicians and Surgeons of Canada (RCPSC) did not recognize GIM as a distinct entity. In response to a societal need to train generalist practitioners who could care for complex patients in an increasingly complex health care setting, the majority of universities across Canada voluntarily developed structured GIM training programs independent of RCPSC recognition. However, interest amongst trainees in GIM was declining, and the GIM workforce in Canada, like that in many other countries, was in danger of serious shortfalls. After much deliberation and consultation, in 2010, the RCPSC recognized GIM as a distinct subspecialty of internal medicine. Since this time, despite the challenges in the educational implementation of GIM as a distinct discipline, there has been a resurgence of interest in this field of medicine. This paper outlines the journey of the Canadian GIM to educational implementation as a distinct discipline, the impact on the discipline, and the implications for the international GIM community.

7 CFR 51.1584 - Internal discoloration.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Internal discoloration. Internal discoloration means discoloration such as is caused by net necrosis or any other type of necrosis, stem-end browning, internal brown spot, or other similar types of discoloration...

7 CFR 51.1584 - Internal discoloration.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Internal discoloration. Internal discoloration means discoloration such as is caused by net necrosis or any other type of necrosis, stem-end browning, internal brown spot, or other similar types of discoloration...

Globalization, international law, and emerging infectious diseases.

PubMed Central

Fidler, D. P.

1996-01-01

The global nature of the threat posed by new and reemerging infectious diseases will require international cooperation in identifying, controlling, and preventing these diseases. Because of this need for international cooperation, international law will certainly play a role in the global strategy for the control of emerging diseases. Recognizing this fact, the World Health Organization has already proposed revising the International Health Regulations. This article examines some basic problems that the global campaign against emerging infectious diseases might face in applying international law to facilitate international cooperation. The international legal component of the global control strategy for these diseases needs careful attention because of problems inherent in international law, especially as it applies to emerging infections issues. PMID:8903206

Global climate change and international security.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karas, Thomas H.

2003-11-01

This report originates in a workshop held at Sandia National Laboratories, bringing together a variety of external experts with Sandia personnel to discuss 'The Implications of Global Climate Change for International Security.' Whatever the future of the current global warming trend, paleoclimatic history shows that climate change happens, sometimes abruptly. These changes can severely impact human water supplies, agriculture, migration patterns, infrastructure, financial flows, disease prevalence, and economic activity. Those impacts, in turn, can lead to national or international security problems stemming from aggravation of internal conflicts, increased poverty and inequality, exacerbation of existing international conflicts, diversion of national andmore » international resources from international security programs (military or non-military), contribution to global economic decline or collapse, or international realignments based on climate change mitigation policies. After reviewing these potential problems, the report concludes with a brief listing of some research, technology, and policy measures that might mitigate them.« less

International Space Station (ISS)

NASA Image and Video Library

1994-07-20

An artist's conception of what the final configuration of the International Space Station (ISS) will look like when it is fully built and deployed. The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide an unprecedented undertaking in scientific, technological, and international experimentation.

Internal vibrations of a molecule consisting of rigid segments. I - Non-interacting internal vibrations

NASA Technical Reports Server (NTRS)

He, X. M.; Craven, B. M.

1993-01-01

For molecular crystals, a procedure is proposed for interpreting experimentally determined atomic mean square anisotropic displacement parameters (ADPs) in terms of the overall molecular vibration together with internal vibrations with the assumption that the molecule consists of a set of linked rigid segments. The internal librations (molecular torsional or bending modes) are described using the variable internal coordinates of the segmented body. With this procedure, the experimental ADPs obtained from crystal structure determinations involving six small molecules (sym-trinitrobenzene, adenosine, tetra-cyanoquinodimethane, benzamide, alpha-cyanoacetic acid hydrazide and N-acetyl-L-tryptophan methylamide) have been analyzed. As a consequence, vibrational corrections to the bond lengths and angles of the molecule are calculated as well as the frequencies and force constants for each internal torsional or bending vibration.

The US DOE EM international program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elmetti, Rosa R.; Han, Ana M.; Roach, Jay A.

2013-07-01

The U.S. Department of Energy (DOE) Office of Environmental Management (EM) conducts international collaboration activities in support of U.S. policies and objectives regarding the accelerated risk reduction and remediation of environmental legacy of the nations' nuclear weapons program and government sponsored nuclear energy research. The EM International Program supported out of the EM Office of the Associate Principal Deputy Assistant Secretary pursues collaborations with foreign government organizations, educational institutions and private industry to assist in identifying technologies and promote international collaborations that leverage resources and link international experience and expertise. In fiscal year (FY) 2012, the International Program awarded eightmore » international collaborative projects for work scope spanning waste processing, groundwater and soil remediation, deactivation and decommissioning (D and D) and nuclear materials disposition initiatives to seven foreign organizations. Additionally, the International Program's scope and collaboration opportunities were expanded to include technical as well as non-technical areas. This paper will present an overview of the on-going tasks awarded in FY 2012 and an update of upcoming international activities and opportunities for expansion into the remainder of FY 2013 and beyond. (authors)« less

Guidelines for international collaborative research.

PubMed

Rosser, W W; Culpepper, L; Lam, C L; Parkerson, G; Poon, V; Weel, C V

1997-08-01

As the global village becomes a reality, there is an increasing need to conduct international collaborative studies in family practice. A workshop at the WONCA meeting in Hong Kong used international attendees to produce a set of guidelines for international research. At the workshop four completed international projects, each using a different strategy, were presented so that common themes might become apparent. The themes were then discussed and guidelines emerged from the process. Seven guidelines emerged for consideration before embarking on an international collaborative research project in family medicine. The guidelines deal with the characteristics of the research question and the importance of communication. The need for simple, brief methods of data collection, funding and pilot testing were identified. The question must be relevant to all participants to maintain interest and measurement tools must be validated to understand the impact of cultural differences in understanding.

Internal displacement in Colombia

PubMed Central

Shultz, James M; Ceballos, Ángela Milena Gómez; Espinel, Zelde; Oliveros, Sofia Rios; Fonseca, Maria Fernanda; Florez, Luis Jorge Hernandez

2014-01-01

This commentary aims to delineate the distinguishing features of conflict-induced internal displacement in the nation of Colombia, South America. Even as Colombia is currently implementing a spectrum of legal, social, economic, and health programs for “victims of armed conflict,” with particular focus on internally displaced persons (IDPs), the dynamics of forced migration on a mass scale within this country are little known beyond national borders.   The authors of this commentary are embarking on a global mental health research program in Bogota, Colombia to define best practices for reaching the displaced population and implementing sustainable, evidence-based screening and intervention for common mental disorders. Presenting the defining characteristics of internal displacement in Colombia provides the context for our work and, more importantly, conveys the compelling and complex nature of this humanitarian crisis. We attempt to demonstrate Colombia’s unique position within the global patterning of internal displacement. PMID:28228997

International Maps | Geospatial Data Science | NREL

Science.gov Websites

International Maps International Maps This map collection provides examples of how geographic information system modeling is used in international resource analysis. The images below are samples of

Solid rocket motor internal insulation

NASA Technical Reports Server (NTRS)

Twichell, S. E. (Editor); Keller, R. B., Jr.

1976-01-01

Internal insulation in a solid rocket motor is defined as a layer of heat barrier material placed between the internal surface of the case propellant. The primary purpose is to prevent the case from reaching temperatures that endanger its structural integrity. Secondary functions of the insulation are listed and guidelines for avoiding critical problems in the development of internal insulation for rocket motors are presented.

International Research Results and Accomplishments From the International Space Station

NASA Technical Reports Server (NTRS)

Ruttley, Tara M.; Robinson, Julie A.; Tate-Brown, Judy; Perkins, Nekisha; Cohen, Luchino; Marcil, Isabelle; Heppener, Marc; Hatton, Jason; Tasaki, Kazuyuki; Umemura, Sayaka;

Internal Wave Generation by Convection

NASA Astrophysics Data System (ADS)

Lecoanet, Daniel Michael

In nature, it is not unusual to find stably stratified fluid adjacent to convectively unstable fluid. This can occur in the Earth's atmosphere, where the troposphere is convective and the stratosphere is stably stratified; in lakes, where surface solar heating can drive convection above stably stratified fresh water; in the oceans, where geothermal heating can drive convection near the ocean floor, but the water above is stably stratified due to salinity gradients; possible in the Earth's liquid core, where gradients in thermal conductivity and composition diffusivities maybe lead to different layers of stable or unstable liquid metal; and, in stars, as most stars contain at least one convective and at least one radiative (stably stratified) zone. Internal waves propagate in stably stratified fluids. The characterization of the internal waves generated by convection is an open problem in geophysical and astrophysical fluid dynamics. Internal waves can play a dynamically important role via nonlocal transport. Momentum transport by convectively excited internal waves is thought to generate the quasi-biennial oscillation of zonal wind in the equatorial stratosphere, an important physical phenomenon used to calibrate global climate models. Angular momentum transport by convectively excited internal waves may play a crucial role in setting the initial rotation rates of neutron stars. In the last year of life of a massive star, convectively excited internal waves may transport even energy to the surface layers to unbind them, launching a wind. In each of these cases, internal waves are able to transport some quantity--momentum, angular momentum, energy--across large, stable buoyancy gradients. Thus, internal waves represent an important, if unusual, transport mechanism. This thesis advances our understanding of internal wave generation by convection. Chapter 2 provides an underlying theoretical framework to study this problem. It describes a detailed calculation of the

Issues in International Rehabilitation.

ERIC Educational Resources Information Center

Nathanson, Jeanne H., Ed.

1991-01-01

Eight articles address issues and programs in international rehabilitation. The issue is introduced by a message from the Assistant Secretary of the United States Department of Education for the Office of Special Education and Rehabilitation Services, Robert R. Davila. Next, "A History of International Rehabilitation" (Nora Ellen Groce)…

The Role of International Law: Formulating International Legal Instruments and Creating International Institutions.

ERIC Educational Resources Information Center

Szasz, Paul C.

1991-01-01

Using as a basis the threat of climatic change resulting from global warming, this article considers the functions that might be assigned to an international regime. For each function individually and collectively, the instruments and institutions that would be required for the various processes are examined. (SLD)

Professional International Service Learning as an International Service Learning Opportunity Appropriate for Graduate or Professional Students

ERIC Educational Resources Information Center

Lightfoot, Elizabeth; Lee, Hee Yun

2015-01-01

Graduate and professional schools are increasingly using short-term international study abroad courses as one way for internationalizing their curriculum. While international service learning can be a means for improving students' engagement in international learning experiences and providing a structure for learning, it is difficult to design…

Internal noise estimates correlate with autistic traits.

PubMed

Vilidaite, Greta; Yu, Miaomiao; Baker, Daniel H

2017-08-01

Previous neuroimaging research has reported increased internal (neural) noise in sensory systems of autistic individuals. However, it is unclear if this difference has behavioural or perceptual consequences, as previous attempts at measuring internal noise in ASD psychophysically have been indirect. Here, we use a "gold standard" psychophysical double-pass paradigm to investigate the relationship between internal noise and autistic traits in the neurotypical population (n = 43). We measured internal noise in three tasks (contrast perception, facial expression intensity perception, and number summation) to estimate a global internal noise factor using principal components analysis. This global internal noise was positively correlated with autistic traits (r s  = 0.32, P = 0.035). This suggests that increased internal noise is associated with the ASD phenotype even in subclinical populations. The finding is discussed in relation to the neural and genetic basis of internal noise in ASD. Autism Res 2017, 10: 1384-1391. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.

Is international travel useful for general practitioners? A survey of international travel scholarships.

PubMed Central

Holden, J; Evans, P

1998-01-01

BACKGROUND: The Royal College of General Practitioners has offered international travel scholarships for the past decade. Each year a number of general practitioners travel from the UK to work or study assisted by the scheme, while others come to this country for similar purposes. AIM: To investigate the value of international scholarships for recipients and others. METHOD: All those receiving awards in 1988-94 were surveyed by postal questionnaire. RESULTS: Fifty-one out of 58 award winners (88%) replied. Almost all cited some of a wide variety of personal benefits from international travel, and some established continuing links with colleagues overseas. Many gave examples of useful results for others, both patients and colleagues. Scholarships appear to have made a significant contribution to careers, especially for those based outside Britain. CONCLUSION: Relatively modest travel scholarships were viewed both favourably in hindsight and produced a wide range of benefits to recipients, colleagues, and patients. International travel should probably be considered more widely in career planning. PMID:9624751

Publishing International Counseling Articles

ERIC Educational Resources Information Center

Hohenshil, Thomas H.; Amundson, Norman E.

2011-01-01

This article begins with a rationale for including international articles in the "Journal of Counseling & Development." Then, 2 general categories of international articles are described. First are articles that provide a general overview of counseling in a particular country. The 2nd category is more general and might involve international…

International Space Station (ISS)

NASA Image and Video Library

1994-12-16

Artist's concept of the International Space Station (ISS) Alpha deployed and operational. This figure also includes the docking procedures for the Space Shuttle (shown with cargo bay open). The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide an unprecedented undertaking in scientific, technological, and international experimentation.

International Education (Working Paper).

ERIC Educational Resources Information Center

Gruson, Edward S.

The history, objectives, and funding patterns for international education are discussed. Attention is directed toward the language and area study centers of the U.S. Office of Education, undergraduate/graduate and scholarly exchange programs, and the support of advanced research in international studies. The main source of funds for language and…

78 FR 11699 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-19

... additional International Business Reply Service (IBRS) Competitive Contract 3 negotiated service agreement... International Business Reply Service Competitive Contract 3 Negotiated Service Agreement, February 11, 2013.... 684, Order Approving International Business Reply Service Competitive Contract 3 Negotiated Service...

INTERNAL HAZARDS ANALYSIS FOR LICENSE APPLICATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

R.J. Garrett

2005-02-17

The purpose of this internal hazards analysis is to identify and document the internal hazards and potential initiating events associated with preclosure operations of the repository at Yucca Mountain. Internal hazards are those hazards presented by the operation of the facility and by its associated processes that can potentially lead to a radioactive release or cause a radiological hazard. In contrast to external hazards, internal hazards do not involve natural phenomena and external man-made hazards. This internal hazards analysis was performed in support of the preclosure safety analysis and the License Application for the Yucca Mountain Project. The methodology formore » this analysis provides a systematic means to identify internal hazards and potential initiating events that may result in a radiological hazard or radiological release during the repository preclosure period. These hazards are documented in tables of potential internal hazards and potential initiating events (Section 6.6) for input to the repository event sequence categorization process. The results of this analysis will undergo further screening and analysis based on the criteria that apply to the performance of event sequence analyses for the repository preclosure period. The evolving design of the repository will be re-evaluated periodically to ensure that internal hazards that have not been previously evaluated are identified.« less

Astronomy and international science diplomacy

NASA Astrophysics Data System (ADS)

Madsen, Claus

2015-08-01

Since WW2, science has played an important, if sometimes overlooked, role in international relations and international diplomacy. The founding of CERN in 1954 and the more recent establishment of SESAME as a major research infrastructure in the Middle East are examples of this. The IAU has played its own role in the field of science diplomacy ranging from quietly fostering interaction between the antagonists of the Cold War period to the world-uniting initiative of the International Year of Astronomy. Beyond the IAU, yet still with clear links to it, we have seen ESO as an example as well as the more recent one of SKA as a vehicle for development and for strengthening international relations.

Innovative Ideas for Coordinating International Space Activities: International Center for Space Medicine, International Space Authority, and other Global Youth Space Initiatives

NASA Astrophysics Data System (ADS)

Marshall, W.

2002-01-01

The Space Generation Forum SGF, at UNISPACE-III, as one of its ten formal recommendations to the United Nations in 1999, put forward the suggestion that the an international space authority should be created. Other recommendations were the establishment of an International Center for Space Medicine, creation of a global space exploration and development program, establishment of a global space (Nobel) prize, and a global space library. These projects are being further developed at the Space Generation Summit (SGS), an event at World Space Congress (WSC) which shall unite international students and young professionals to develop a youth vision and strategy for the peaceful uses of space. SGS, endorsed by the United Nations, will take place from October 11- 13th, during which the 200 delegates will discuss ongoing youth space activities, particularly those stemming from the UNISPACE-III/SGF and taken forward by the Space Generation Advisory Council. Delegates will address a variety of topics with the goal of devising new recommendations according to the theme, 'Accelerating Our Pace in Space'. The material presented here and in other technical sessions throughout WSC includes the findings of these discussions. In this paper, we present the International Space Authority idea together with recommendations on how that might be taken forward. The purpose of such an organization would be to allow: 1. Oversight and enforcement for the balanced regulation of multiple interests in space 2. Access for all peoples to the material benefits and knowledge and understanding enabled by the exploration and 3. Pooling of national and industry resources for the creation of space infrastructure, missions and enterprises for Operating principles: 1. The ISA regulatory regime would encourage commercialization and the harnessing of competitive market 2. Consistent with its charter to ensure access to all peoples, all UN member states and appropriate NGOs would 3. Close coordination with

International Humanitarian Award.

PubMed

2016-11-01

The International Humanitarian Award recognizes extraordinary humanitarian services and activism by psychologists, including professional and volunteer work conducted primarily in the field with underserved populations. Award recipients are psychologists who, by their extraordinary service at a difficult time, improve the lives and contribute to the well-being of people in a large or small geographic area anywhere in the world. The 2016 recipient of the APA International Humanitarian Award was selected by the 2015 Committee on International Relations in Psychology (CIRP). The members of the 2015 CIRP were Rehman Abdulrehman, PhD (Chair); Gonzalo Bacigalupe, EdD; Silvia S. Canetto, PhD; Amanda Clinton, PhD; Melissa L. Morgan Consoli, PhD; Chryse G. Hatzichristou, PhD; Arpana G. Inman, PhD; Lori Foster Thompson, PhD; and Danny Wedding, PhD. Dr. Abdulrehman, Dr. Morgan Consoli, Dr. Thompson, and Dr. Wedding were members of the subcommittee for the 2016 award. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

International Humanitarian Award.

PubMed

2017-12-01

The International Humanitarian Award recognizes extraordinary humanitarian services and activism by psychologists, including professional and volunteer work conducted primarily in the field with underserved populations. Award recipients are psychologists who, by their extraordinary service at a difficult time, improve the lives and contribute to the well-being of people in a large or small geographic area anywhere in the world. The 2017 recipient of the APA International Humanitarian Award was selected by the 2016 Committee on International Relations in Psychology (CIRP). The members of the 2016 CIRP were Melissa Morgan Consoli, PhD, and Arpana G. Inman, PhD (Co-chairs); Rehman Abdulrehman, PhD; Gonzalo Bacigalupe, EdD; Frederic Bemak, EdD; Brigitte Khoury, PhD; Susan Nolan, PhD; Nancy Sidun, PsyD; and Danny Wedding, PhD. Dr. Morgan Consoli, Dr. Inman, Dr. Nolan, and Doctor Sidun were members of the subcommittee for the 2017 award. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

The International Standard for Oxytetracycline

PubMed Central

Humphrey, J. H.; Lightbown, J. W.; Mussett, M. V.; Perry, W. L. M.

1955-01-01

The first attempt to set up an international standard for oxytetracycline, using oxytetracycline hydrochloride, failed because of difficulties in obtaining a preparation whose moisture content was uniform after distribution into ampoules. A preparation of dihydrate of oxytetracycline base was obtained instead, and was compared in an international collaborative assay with a sample of oxytetracycline hydrochloride, which was the current working standard of Chas. Pfizer & Co., Inc., USA. The results of the collaborative assay showed that the potency of the dihydrate was uniform, and that it was a suitable preparation for use as the International Standard. Evidence was obtained, however, that the reference preparation at the time of examination was less potent than had been originally supposed, and that it was hydrated. The potency of the proposed international standard was recalculated after allowance for water in the reference preparation, and the resulting biological potency agreed well with that to be expected on the basis of the physicochemical properties of the preparation. It was agreed, therefore, that the recalculated values should be used, and the preparation of oxytetracycline base dihydrate used in the collaborative assay is established as the International Standard for Oxytetracycline with a potency of 900 International Units per mg. PMID:13284563

Intern Programs

Science.gov Websites

International Partnership) thumbnail For Italian physics & engineering grads PST - Pre-Service Teacher Internship (No longer active) thumbnail For STEM pre-service teachers Fermi National Accelerator Laboratory

77 FR 76091 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-26

... history. The Commission added International Business Reply Service Contract 1 to the competitive product... an expired International Business Reply Service (IBRS) competitive contract.\\1\\ The Postal Service... International Business Reply Service Competitive Contract 1 Negotiated Service Agreement, December 14, 2012...

77 FR 16568 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

...-filed Postal Service request to enter into an additional International Business Reply Service contract... additional International Business Reply Service (IBRS) contract.\\1\\ The Postal Service asserts that the... Service Filing of a Functionally Equivalent International Business Reply Service Competitive Contract 3...

78 FR 54687 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... Service filing seeking to include a new International Business Reply Service (IBRS) agreement within the... Postal Service seeks to include a new International Business Reply Service (IBRS) agreement (Agreement... a Functionally Equivalent International Business Reply Service Competitive Contract 3 Negotiated...

77 FR 10577 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-22

...-filed Postal Service request to enter into an additional International Business Reply Service contract... additional International Business Reply Service (IBRS) contract.\\1\\ The Postal Service asserts that the... United States Postal Service Filing of a Functionally Equivalent International Business Reply Service...

Higher Education: Handbook of Theory and Research. Volume XIII.

ERIC Educational Resources Information Center

Smart, John C., Ed.

The 10 papers in this handbook consider higher education theory and research. Following an opening essay, "Recollections and Reflections," by C. Robert Pace, which offers reflections on higher education as a field, on its evolution, and it future research needs, papers include: "Reflections on the Study of Effective College Teaching…

Rare coagulation disorders: fibrinogen, factor VII and factor XIII.

PubMed

de Moerloose, P; Schved, J-F; Nugent, D

2016-07-01

Rare coagulation disorders (RCDs) include the inherited deficiencies of fibrinogen, factor (F) II, FV, combined FV and VIII, FVII, FX, combined FVII and X, FXI, FXIII and combined congenital deficiency of vitamin K-dependent factors (VKCFDs). Despite their rarity, a deep comprehension of all these disorders is essential to really understand haemostasis. Indeed, even if they share some common features each RCD has some particularity which makes it unique. In this review, we focus on three disorders: fibrinogen, FVII and FXIII. © 2016 John Wiley & Sons Ltd.

25 CFR 36.40 - Standard XIII-Library/media program.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION MINIMUM ACADEMIC STANDARDS FOR THE BASIC EDUCATION OF INDIAN CHILDREN AND NATIONAL CRITERIA FOR DORMITORY SITUATIONS Instructional Support... inclusive of materials located in the classrooms shall be maintained. This category includes some of each of...

Physical and geometrical parameters of VCBS XIII: HIP 105947

NASA Astrophysics Data System (ADS)

Gumaan Masda, Suhail; Al-Wardat, Mashhoor Ahmed; Pathan, Jiyaulla Khan Moula Khan

2018-06-01

The best physical and geometrical parameters of the main sequence close visual binary system (CVBS), HIP 105947, are presented. These parameters have been constructed conclusively using Al-Wardat’s complex method for analyzing CVBSs, which is a method for constructing a synthetic spectral energy distribution (SED) for the entire binary system using individual SEDs for each component star. The model atmospheres are in its turn built using the Kurucz (ATLAS9) line-blanketed plane-parallel models. At the same time, the orbital parameters for the system are calculated using Tokovinin’s dynamical method for constructing the best orbits of an interferometric binary system. Moreover, the mass-sum of the components, as well as the Δθ and Δρ residuals for the system, is introduced. The combination of Al-Wardat’s and Tokovinin’s methods yields the best estimations of the physical and geometrical parameters. The positions of the components in the system on the evolutionary tracks and isochrones are plotted and the formation and evolution of the system are discussed.

Postgraduate education in internal medicine in Europe.

PubMed

Cranston, Mark; Slee-Valentijn, Monique; Davidson, Christopher; Lindgren, Stefan; Semple, Colin; Palsson, Runolfur

2013-10-01

Limited information exists on the framework and content of postgraduate education in internal medicine in Europe. This report describes the results of a survey of postgraduate training in internal medicine in the European countries. Two online questionnaire-based surveys were carried out by the European Board of Internal Medicine, one on the practice of internists and the other on postgraduate training in internal medicine. The national internal medicine societies of all 30 member countries of the European Federation of Internal Medicine were invited to participate. The responses were reviewed by internal medicine residents from the respective countries and summaries of the data were sent to the national societies for approval. Descriptive analysis of the data on postgraduate training in internal medicine was performed. Twenty-seven countries (90%) completed the questionnaire and approved their datasets. The length of training ranged from four to six years and was commonly five years. The majority of countries offered training in internal medicine and a subspecialty. A common trunk of internal medicine was frequently a component of subspecialty training programmes. Hospital inpatient service was the predominant setting used for training. A final certifying examination was in place in 14 countries. Although some similarities exists, there appear to be significant differences in the organisation, content and governance of postgraduate training in internal medicine between the European countries. Our findings will prove invaluable for harmonisation of training and qualification in internal medicine in Europe. © 2013.

ILO - International Migration Programme.

PubMed

Boudraa, Miriam

2011-01-01

In a wide International Context characterised not only by the economical development but also by the social, cultural, political and individual development, we witness more and more to a exchange between the developed and the developing countries, which can be translated especially in the migration of the work force. In theory, all countries are either countries of origin either countries of transit or destination, and they are all responsible for the rights of migrant workers by promoting the rights, by monitoring and by preventing the abusive conditions. The process of migration of the workforce can be divided into three stages: the first coincides with the period prior to departure, the second is represented by the aftermath of the departure and the period of stay in the country of destination, the third stage corresponds to the return in the country of origin. The workers must be protected throughout this process by the international organizations that perform the catalytic role of communication and exchange between countries, for the only purpose of protecting the rights of immigrant and/or immigrants workers. The responsibility for the protection of workers is divided among the various players in the International Labour Organisation. Every country has to apply measures according to the international standards regarding workers' rights, standards that guide the various countries in the formulation and implementation of their policies and legislation. These standards are suggested by International Conventions, the ILO Conventions and other international instruments such as the human rights instrument. There has been a big step forward once the ILO Fundamental Conventions and Conventions on Migrant Workers where implemented and this implementation represented the use of the Guidelines "ILO Multilateral Framework on Labour Migration".

International Education and Institutional Accreditation.

ERIC Educational Resources Information Center

Crow, Steven D.

1988-01-01

Questions whether voluntary self-regulation as practiced through institutional accreditation can adequately regulate expanding international education activities. Points to challenges related to legality, international linkages, curricula, and regionalism. (DMM)

78 FR 53504 - Internal Revenue Service

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-29

... DEPARTMENT OF THE TREASURY Internal Revenue Service Proposed Collection; Comment Request for Revenue Procedure 2007-37 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for... Gerald J. Shields at Internal Revenue Service, room 6129, 1111 Constitution Avenue NW., Washington, DC...

[Internal and external haemorrhoids].

PubMed

Schuurman, J P; Go, P M N Y H

2011-01-01

In this article, we present 3 cases of patients with different types of haemorrhoidal disease. The first patient is a 27-year-old woman who had been experiencing incidental rectal blood loss without pain during defecation for 3 months. The second patient is a 76-year-old woman who had been bothered by varying degrees of pain from a swelling nearby the anus for 1 year. The third case involves a 31-year-old man who had had continuous severe pain in the anal area for 3 consecutive days. The first patient appeared to have internal hemorrhoids, whereas different forms of external hemorrhoids affected the patients in the other 2 cases. Internal haemorrhoids develop from the intraluminal corpus cavernosum recti; external haemorrhoids from the perianal marginal veins. Patients with internal haemorrhoids present with symptoms that include blood loss and prolaps feeling during defecation. In patients with external haemorrhoids pain is the prominent symptom. Internal haemorrhoids are treated either conservatively or surgically, depending upon their severity. Considering external haemorrhoidal disease surgical treatment provides the most rapid and persistent relief of symptoms.

Internal displacement in Burma.

PubMed

Lanjouw, S; Mortimer, G; Bamforth, V

2000-09-01

The internal displacement of populations in Burma is not a new phenomenon. Displacement is caused by numerous factors. Not all of it is due to outright violence, but much is a consequence of misguided social and economic development initiatives. Efforts to consolidate the state by assimilating populations in government-controlled areas by military authorities on the one hand, while brokering cease-fires with non-state actors on the other, has uprooted civilian populations throughout the country. Very few areas in which internally displaced persons (IDPs) are found are not facing social turmoil within a climate of impunity. Humanitarian access to IDP populations remains extremely problematic. While relatively little information has been collected, assistance has been focused on targeting accessible groups. International concern within Burma has couched the problems of displacement within general development modalities, while international attention along its borders has sought to contain displacement. With the exception of several recent initiatives, few approaches have gone beyond assistance and engaged in the prevention or protection of the displaced.

International energy annual 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-02-01

The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power, geothermal, solar, and wind electric power, biofuels energy for the US, and biofuels electric power for Brazil. New in the 1996 edition are estimates of carbon dioxide emissions from the consumption of petroleum and coal,more » and the consumption and flaring of natural gas. 72 tabs.« less

Cnidarian internal stinging mechanism

PubMed Central

Schlesinger, Ami; Zlotkin, Eliahu; Kramarsky-Winter, Esti; Loya, Y.

2008-01-01

Stinging mechanisms generally deliver venomous compounds to external targets. However, nematocysts, the microscopic stinging organelles that are common to all members of the phylum Cnidaria, occur and act in both external and internal tissue structures. This is the first report of such an internal piercing mechanism. This mechanism identifies prey items within the body cavity of the sea anemone and actively injects them with cytolytic venom compounds. Internal tissues isolated from sea anemones caused the degradation of live Artemia salina nauplii in vitro. When examined, the nauplii were found to be pierced by discharged nematocysts. This phenomenon is suggested to aid digestive phagocytic processes in a predator otherwise lacking the means to masticate its prey. PMID:19129118

Learning Activities for International Business.

ERIC Educational Resources Information Center

Haynes, Thomas

1998-01-01

The National Standards for Business Education include nine areas relating to international business: awareness, communication, environmental factors, ethics, finance, management, marketing, import/export, and organizational structure of international business. (SK)

Wellness at Air Command and Staff College: Impacting Total Force Readiness Through Tomorrow’s Leaders

DTIC Science & Technology

1998-04-01

Joseph P. Opatz, ed. [Association for Worksite Health Promotion], Economic Impact of Worksite Health Promotion (Champaign, IL: Human Kinetics Publishers...Employee Health Promotion Programs (Champaign, IL: Human Kinetics Publishers, 1992), viii. 23 Erfurt, et al., 272. 24 O’Donnell and Harris, xiii. 25 Ibid...Champaign, IL: Human Kinetics Publishers, 1992), viii-ix. 40 Glossary ACSC Air Command and Staff College AU Air University AWC Air War College AY Academic

Project CHECO Southeast Asia Report. Fixed Wing Gunships in SEA (Jul 69 - Jul 71)

DTIC Science & Technology

1971-11-30

charac- teristics and components.) AC -ll9Gs were deployed as needed to various bases including Phu Cat , 3mPhan Rang, Da Nang, and Tan Son Nhut, but...270815Z Feb 70 which I cites the performance of RLAF AC -47 crews is on CHECO microfilm reel S-364. Other documents are in the process of being microfilmed...xiii OVERVIEW...................................................... xiv CHAPTER I - AC -47 COMBAT OPERATION

The need for a regional framework for marine scientific research in the Black Sea and Mediterranean Sea.

PubMed

Oral, Nilufer

2014-10-01

One of the important contributions of the 1982 United Nations Law of the Sea Convention (UNCLOS) is Part XIII on Marine Scientific Research (MSR). UNCLOS recognizes the general rule that all states have the right to conduct MSR subject to rights and duties of other states under the convention and in addition, the obligation to promote and facilitate MSR. Copyright © 2014 Elsevier B.V. All rights reserved.

The Maoist Movement and Its Impact on the Democratic Transition of Nepal

DTIC Science & Technology

2015-03-01

314 Similarly, the Maoists’ popular ban on gambling and alcohol was another prominent campaign. According to Shah, the banning of alcohol garnered...and making our stay meaningful and joyous. xiii THIS PAGE INTENTIONALLY LEFT BLANK xiv I. INTRODUCTION The Maoist insurgency in Nepal had... relationship between “rulers and the ruled” must be smooth.2 So far, Nepalese politics has not achieved this state, even after its most recent transition

Foundry Manual

DTIC Science & Technology

1958-01-01

ramming main part of mold or loose mold- ing sand used to support green cores while baking. Bail. Hoop or connection between the crane hook ...Crystallization 3 Heat Transfer 4 Gases in Metals 5 Summary 5 Chapter II. Designing a Casting 15 Strength Requirements 15 Stress Concentrations 15... Stress -Relief Anneal 180 Reasons for Heat Treatment 179 Aluminum 181 Iron and Steel 181 Monel 183 Summary 183 Chapter XIII. Composition of

Thermal Characterization of a Hall Effect Thruster

DTIC Science & Technology

2008-03-01

View Factor A = Area θ = Angle R = Distance xiii J = Radiosity q = Heat Transfer Rate W = Radiated Power U = Voltage C...summation rule. 1 1 N ij j F = =∑ (18) Radiosity (Ji) takes into account both radiation emitted and reflected from a surface. Analyzing radiation...exchanges between two surfaces is made easier with a few assumptions. Each surface is assumed isothermal and characterized by a uniform radiosity

An Approach to the Management of Hazardous Materials.

DTIC Science & Technology

1981-09-01

fluoride carbon disulfide carbon monoxide hydrochloric acid hydrogen sulfide acetone cyanohydrin phosgene Group XII: Poison B - Meeflaneous a) Gases...b) Liquids sulfur dioxide bromine chlorine boron trifluoride Group XIII: Poison C Group XIV: Poison D Liquid Gas tetraethyl lead fluorine Group XV...with a high and o Nitric acid leaks from a 5,000 gallon storage tank In a growing concentration of electronics industries. Over plant one night and

A System Approach to Navy Medical Education and Training. Appendix 5. Neuropsychiatric Technician.

DTIC Science & Technology

1974-08-31

phrased behavioral statements. Through the use of special programs, task inventories are prepared, printouts for special purposes are created following ...the Response Guide (p. xiii) at the perforation, and use the correct side to respond to each task or instrument found on the following white pages...response data. They can be processed and manipulated only by high speed computer capability using rigorously designed specialty programs. In addition to

Scaling Bulk Data Analysis with Mapreduce

DTIC Science & Technology

2017-09-01

Submitted in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE IN COMPUTER SCIENCE from the NAVAL POSTGRADUATE SCHOOL September...2017 Approved by: Michael McCarrin Thesis Co-Advisor Marcus S. Stefanou Thesis Co-Advisor Peter J. Denning Chair, Department of Computer Science iii...98 xiii THIS PAGE INTENTIONALLY LEFT BLANK xiv List of Acronyms and Abbreviations CART Computer Analysis and Response Team DELV Distributed Environment

Countering Al-Shabaab: A Case to Minimize Transnational Terrorist Threats Against Uganda

DTIC Science & Technology

2011-12-01

Region. ...31 xii THIS PAGE INTENTIONALLY LEFT BLANK xiii LIST OF ACRONYMS AND ABBREVIATIONS AMISOM African Union Mission in Somalia ANC African...National Congress AQAP Al-Qaeda in the Arab Peninsula AQI Al-Qaeda in Iraq ARS Alliance for the Re-liberation of Somalia AU African Union COG...Bureau of Investigation GIMF Global Islamic Media Front HOA Horn of Africa ICU Islamic Courts Union ILDMH Ice Link Discotheque in Makindye House

International Satellite Law

NASA Astrophysics Data System (ADS)

von der Dunk, Frans

2017-07-01

International space law is generally considered to be a branch of public international law. In that sense, it constitutes a "subset of rules, rights and obligations of states within the latter specifically related to outer space and activities in or with respect to that realm." Dealing with an inherently international realm, much of it had been developed in the context of the United Nations, where the key treaties are even adhered to by all major space-faring countries. In addition, other sources—including not only customary international law but also such disputed concepts as "soft law" and political guidelines and recommendations—also contributed to the development of a general framework legal regime for all of mankind's endeavors in or with respect to outer space. Originally, this predominantly included scientific and military/security-related activities, but with the ongoing development of technology and a more practical orientation, it increasingly came to encompass many more civilian and, ultimately, even commercial activities, largely through downstream applications originating from or depending on space technology and space activities. Important here are the overarching, usually more theoretical aspects of international space law, which include how it was developed or continues to be developed, what special roles do "soft law" or the military aspects of space activities play in this regard, and how do national space laws (also) serve as a tool for interpretation of international space law. Also important is the special category of launches and other space operations in the sense of moving space objects safely into, through and—if applicable—back from outer space. Without such operations, space activities would be impossible, yet they bring with them special concerns; for instance, in terms of liability, the creation of space debris and even the legal status and possible commercialization of natural resources produced from celestial bodies. Finally

First-Year International Students' Perceived Impact of the International Student Services Office

ERIC Educational Resources Information Center

Chissoe, David H.

2017-01-01

As international student attendance on college campuses in the US continues to increase in record numbers, International Student Services (ISS) offices across the country are tasked with providing services to aid the growing number and variety of sojourners in their transition to life on campus in the United States. This dissertation is a…

5 CFR 950.201 - National/international eligibility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false National/international eligibility. 950... PRIVATE VOLUNTARY ORGANIZATIONS Eligibility Provisions § 950.201 National/international eligibility. (a... for inclusion in the National/International and International parts of the Charity List. (2) Determine...

International Baccalaureate Diploma Programme: Examining College Readiness

ERIC Educational Resources Information Center

Conley, David; McGaughy, Charis; Davis-Molin, Whitney; Farkas, Rachel; Fukuda, Erin

2014-01-01

The International Baccalaureate (IB) works with schools, governments, and international organizations to develop challenging programmes of international education and rigorous assessment. This three-phase study prepared by the Educational Policy Improvement Center (EPIC) on behalf of the International Baccalaureate Organization explored the impact…

International Students' Perceptions of University Life

ERIC Educational Resources Information Center

Perry, Cody J.; Lausch, David W.; Weatherford, Jenny; Goeken, Ryan; Almendares, Maria

2017-01-01

International students provide economic, cultural, and academic benefits to universities throughout the nation. However, many international students lack the support necessary to be successful and satisfied with their education. In order to determine international students' perceptions of their university experience, an online survey was emailed…

10 CFR 835.102 - Internal audits.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Internal audits. 835.102 Section 835.102 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Management and Administrative Requirements § 835.102 Internal audits. Internal audits of the radiation protection program, including examination of program...

75 FR 29818 - Internal Revenue Service

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

... DEPARTMENT OF THE TREASURY Internal Revenue Service Advisory Group to the Internal Revenue Service Tax Exempt and Government Entities Division (TE/GE); Meeting AGENCY: Internal Revenue Service (IRS..., Director, TE/GE Communications and Liaison; 1111 Constitution Ave., NW.; SE:T:CL--Penn Bldg; Washington, DC...

47 CFR 73.1650 - International agreements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 4 2011-10-01 2011-10-01 false International agreements. 73.1650 Section 73... BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1650 International agreements. (a) The... States that have been established by or pursuant to treaties or other international agreements...

10 CFR 835.102 - Internal audits.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Internal audits. 835.102 Section 835.102 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Management and Administrative Requirements § 835.102 Internal audits. Internal audits of the radiation protection program, including examination of program...

10 CFR 835.102 - Internal audits.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Internal audits. 835.102 Section 835.102 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Management and Administrative Requirements § 835.102 Internal audits. Internal audits of the radiation protection program, including examination of program...

10 CFR 835.102 - Internal audits.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Internal audits. 835.102 Section 835.102 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Management and Administrative Requirements § 835.102 Internal audits. Internal audits of the radiation protection program, including examination of program...

10 CFR 835.102 - Internal audits.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Internal audits. 835.102 Section 835.102 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Management and Administrative Requirements § 835.102 Internal audits. Internal audits of the radiation protection program, including examination of program...

Internal Evaluation, Historically Speaking

ERIC Educational Resources Information Center

Mathison, Sandra

2011-01-01

The author analyzes the growth and nature of internal evaluation from the 1960s to the present and suggests that internal evaluation has been on the increase because of its perceived importance. Although the 1960s were characterized by a rich intellectual development of evaluation theory and practice, the fiscal conservatism of the 1980s ushered…

International Space Station (ISS)

NASA Image and Video Library

1995-07-11

Artist's concept for Phase III of the International Space Station (ISS) as shown here in its completed and fully operational state with elements from the United States, Europe, Canada, Japan, and Russia. Sixteen countries are cooperating to provide a multidisciplinary laboratory, technology test bed, and observatory that will provide an unprecedented undertaking in scientific, technological, and international experimentation.

International Trade and Protectionism.

ERIC Educational Resources Information Center

Stanford Univ., CA. Stanford Program on International and Cross Cultural Education.

This unit is designed to investigate the reasons for international trade and the issue of trade protectionism by focusing on the case study of the U.S. trade relationship with Taiwan. The unit begins with a simulation that highlights the concepts of global interdependence, the need for international trade, and the distribution of the world's…

Canadian Policy Responses to International Comparison Testing

ERIC Educational Resources Information Center

Volante, Louis

2013-01-01

This paper examines policy responses across Canada to international student assessment programs such as the program for international student assessment, trends in international mathematics and science study, and progress in international reading and literacy study. Literature reviewed included refereed and non-refereed journal articles,…

22 CFR 41.24 - International organization aliens.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false International organization aliens. 41.24... aliens. (a) Definition of international organization. “International organization” means: (1) Any public...)(27)(I), INTELSAT or any successor or separated entity thereof. (b) Aliens coming to international...

22 CFR 41.24 - International organization aliens.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false International organization aliens. 41.24... aliens. (a) Definition of international organization. “International organization” means: (1) Any public...)(27)(I), INTELSAT or any successor or separated entity thereof. (b) Aliens coming to international...

22 CFR 41.24 - International organization aliens.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false International organization aliens. 41.24... aliens. (a) Definition of international organization. “International organization” means: (1) Any public...)(27)(I), INTELSAT or any successor or separated entity thereof. (b) Aliens coming to international...

22 CFR 41.24 - International organization aliens.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false International organization aliens. 41.24... aliens. (a) Definition of international organization. “International organization” means: (1) Any public...)(27)(I), INTELSAT or any successor or separated entity thereof. (b) Aliens coming to international...

22 CFR 41.24 - International organization aliens.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false International organization aliens. 41.24... aliens. (a) Definition of international organization. “International organization” means: (1) Any public...)(27)(I), INTELSAT or any successor or separated entity thereof. (b) Aliens coming to international...

5 CFR 9901.516 - Internal placement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Internal placement. 9901.516 Section 9901... PERSONNEL SYSTEM (NSPS) Staffing and Employment External Recruitment and Internal Placement § 9901.516 Internal placement. (a) Determining levels of work and movement within and across career groups. The...

International Students: A Vulnerable Student Population

ERIC Educational Resources Information Center

Sherry, Mark; Thomas, Peter; Chui, Wing Hong

2010-01-01

This study examines the experiences of international students at The University of Toledo, where international students comprise approximately 10% of the student population. It highlights problems international students experience such as adapting to a new culture, English language problems, financial problems and lack of understanding from the…

The International Responsibility of Higher Education.

ERIC Educational Resources Information Center

American Association of State Colleges and Universities, Washington, DC.

International education encompasses: (1) the international content of curricula; (2) the international movement of scholars and students concerned with training and research; and (3) the arrangements engaging United States education abroad in technical assistance and educational cooperation programs. Its purposes are to liberate the mind and to…

The Internationality Imperative in Academia. The Ascent of Internationality as an Academic Virtue

ERIC Educational Resources Information Center

Hamann, Julian; Zimmer, Lena M.

2017-01-01

The paper investigates internationality as an academic virtue that is highly relevant for research biographies. The discursive trajectory of this virtue is assessed by comparing ascriptions of internationality in 216 academic obituaries from the US, UK and Germany, from physics, sociology and history, and from the 1960s, 1980s and 2000s. Our…

International ties. [international cooperation in the space sciences

NASA Technical Reports Server (NTRS)

1980-01-01

A historical overview of NASA's participation in international activities in space science is given. The Ariel, Alouette, Isis, and San Marco satellite programs are addressed along with sounding rocket and ground based projects. Relations and cooperation with the Soviet Union are also discussed.