[Idea and practice of ZHU Lian concerning acupuncture education].

PubMed

Zhang, Li-Jian; Liu, Bing; Xu, Qing-Yan; Ran, Sheng-Qi

2014-08-01

ZHU Lian is a deceased famous acupuncture and Moxibustion specialist, the first director and the founder of institute of Acupuncture-Moxibustion of China Academy of Chinese Medical Sciences. This article discusses the thought and idea of education and teaching of acupuncture-moxibustion from the following three aspects: diversified education and training mode, teaching idea of new acupuncture-moxibustion with a lot of characteristics, and the founding of professional acupuncture-moxibustion college. All above have both distinct characteristics of the times and positively enlightening significance of reality.

Religious Identity and Cultural Refashioning: Educational Constraints for Migrant Muslim Hui University Students in China

ERIC Educational Resources Information Center

Zhao, Dong

2014-01-01

This study discusses the educational constraints facing Muslim Hui students and the measures that should be pondered by the Chinese government to address these constraints. Three key research questions are addressed: (1) How does the mainstream Han, Confucian, or the state ideology interact with Hui students' culture? (2) In what ways do ethnic…

[A cross-sectional survey on behavior problems among eco-migrant children of Hui and Han in Ningxia, China].

PubMed

Yan, Guoli; Fang, Jianqun; Zhang, Zhaoxia; Feng, Liping; Wu, Jinrong; Ma, Fuli; Chen, Shiqi; Zhao, Ranran; Wang, Yingli; Wang, Zhizhong

2014-02-01

To investigate the detection rate and correlates of behavioral problems among eco-migrant children in Hui and Han ethnicities. Using multistage randomized sampling method, 2 653 eco-migrant teenagers, 3 174 indigenous and 2 334 homeland peers were selected. Their parents were asked to finish the Achenbach's Child Behavior Checklist (CBCL) and a self-developed correlates questionnaire. 765 eco-migrant children with behavioral problems were detected, with detection rate as 28.8%, higher than that of homeland group (24.2%) and native group (19.3%) (χ(2) = 73.547, P < 0.012 5). Ecological migration mainly influenced factors as bad contacts, depression, obsessive-compulsive, discipline, attack for boys aged 6-11, bad contacts for boys aged 12-16 and extraversion behavioral problems for girls aged 12-16, in Hui. These factors both associated to eco-migrant children's behavioral problems in Hui and Han:cesarean section (OR = 1.863, 95% CI:1.144-3.035, for Han) and (OR = 2.979, 95% CI:2.067-4.293, for Hui), physical defects (OR = 1.730, 95%CI:1.087-2.751, for Han) and (OR = 2.552, 95%CI:1.649-3.950, for Hui), arable as a main income way(OR = 1.272, 95%CI:1.066-1.518, for Han) and (OR = 1.212, 95%CI: 1.033-1.422, for Hui), parents' education level above middle school (OR = 0.709, 95% CI: 0.539-0.932, for Han) and (OR = 0.698, 95%CI: 0.542-0.898, for Hui), parents' frequently in good mood (OR = 0.710, 95%CI:0.613-0.821, for Han) and (OR = 0.826, 95%CI:0.718-0.949, for Hui). However, major diseases in the process of growth (OR = 1.794, 95% CI:1.163-2.767), and parents with chronic illness or disability (OR = 1.463, 95% CI:1.061-2.016) only associated with that in Han;single-parent or remarried families(OR = 1.583, 95% CI:1.078-2.325), parents often drinking (OR = 1.557, 95%CI:1.019- 2.379), the time of parents' work longer than half a year (OR = 1.494, 95% CI:1.197-1.864), parents' more content to life now(OR = 0.813, 95% CI:0.700-0.945), and children in older age (OR = 0

Genetic evidence for an East Asian origin of Chinese Muslim populations Dongxiang and Hui

PubMed Central

Yao, Hong-Bing; Wang, Chuan-Chao; Tao, Xiaolan; Shang, Lei; Wen, Shao-Qing; Zhu, Bofeng; Kang, Longli; Jin, Li; Li, Hui

2016-01-01

There is a long-going debate on the genetic origin of Chinese Muslim populations, such as Uygur, Dongxiang, and Hui. However, genetic information for those Muslim populations except Uygur is extremely limited. In this study, we investigated the genetic structure and ancestry of Chinese Muslims by analyzing 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations in Gansu province. Both genetic distance and Bayesian-clustering methods showed significant genetic homogeneity between the two Muslim populations and East Asian populations, suggesting a common genetic ancestry. Our analysis found no evidence of substantial gene flow from Middle East or Europe into Dongxiang and Hui people during their Islamization. The dataset generated in present study are also valuable for forensic identification and paternity tests in China. PMID:27924949

Failure to replicate the Mehta and Zhu (2009) color-priming effect on anagram solution times.

PubMed

Steele, Kenneth M

2014-06-01

Mehta and Zhu (Science, 323, 1226-1229, 2009) hypothesized that the color red induces avoidance motivation and that the color blue induces approach motivation. In one experiment, they reported that anagrams of avoidance motivation words were solved more quickly on red backgrounds and that approach motivation anagrams were solved more quickly on blue backgrounds. Reported here is a direct replication of that experiment, using the same anagrams, instructions, and colors, with more than triple the number of participants used in the original study. The results did not show the Mehta and Zhu color-priming effects, even though statistical power was sufficient to detect the effect. The results call into question the existence of their color-priming effect on the solution of anagrams.

Forensic molecular genetic diversity analysis of Chinese Hui ethnic group based on a novel STR panel.

PubMed

Fang, Yating; Guo, Yuxin; Xie, Tong; Jin, Xiaoye; Lan, Qiong; Zhou, Yongsong; Zhu, Bofeng

2018-03-26

In present study, the genetic polymorphisms of 22 autosomal short tandem repeat (STR) loci were analyzed in 496 unrelated Chinese Xinjiang Hui individuals. These autosomal STR loci were multiplex amplified and genotyped based on a novel STR panel. There were 246 observed alleles with the allele frequencies ranging from 0.0010 to 0.3609. All polymorphic information content values were higher than 0.7. The combined power of discrimination and the combined probability of exclusion were 0.999999999999999999999999999426766 and 0.999999999860491, respectively. Based on analysis of molecular variance method, genetic differentiation analysis between the Xinjiang Hui and other reported groups were conducted at these 22 loci. The results indicated that there were no significant differences in statistics between Hui group and Northern Han group (including Han groups from Hebei, Henan, Shaanxi provinces), and significant deviations with Southern Han group (including those from Guangdong, Guangxi provinces) at 7 loci, and Uygur group at 10 loci. To sum up, these 22 autosomal STR loci were high genetic polymorphic in Xinjiang Hui group.

Hui Students' Identity Construction in Eastern China: A Postcolonial Critique

ERIC Educational Resources Information Center

Wang, Yuxiang; Phillion, JoAnn

2011-01-01

In this article, we explored Hui students' lived experiences in school in eastern China and the impact of their experiences on their identity construction. We used postcolonial theory as a theoretical framework and narrative inquiry as a research methodology to guide questions that we asked, data collection, data analysis, and interpretation and…

Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats.

PubMed

Cheng, Chen; Lin, Jia-zhen; Li, Li; Yang, Jun-ling; Jia, Wei-wei; Huang, Yu-hong; Du, Fei-fei; Wang, Feng-qing; Li, Mei-juan; Li, Yan-fen; Xu, Fang; Zhang, Na-ting; Olaleye, Olajide E; Sun, Yan; Li, Jian; Sun, Chang-hai; Zhang, Gui-ping; Li, Chuan

2016-04-01

Monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) are believed to be pharmacologically important for the antiseptic herbal injection XueBiJing. This study was designed to characterize the pharmacokinetics and disposition of monoterpene glycosides. Systemic exposure to Chishao monoterpene glycosides was assessed in human subjects receiving an intravenous infusion and multiple infusions of XueBiJing injection, followed by assessment of the pharmacokinetics of the major circulating compounds. Supportive rat studies were also performed. Membrane permeability and plasma-protein binding were assessed in vitro. A total of 18 monoterpene glycosides were detected in XueBiJing injection (content levels, 0.001-2.47 mmol/L), and paeoniflorin accounted for 85.5% of the total dose of monoterpene glycosides detected. In human subjects, unchanged paeoniflorin exhibited considerable levels of systemic exposure with elimination half-lives of 1.2-1.3 h; no significant metabolite was detected. Oxypaeoniflorin and albiflorin exhibited low exposure levels, and the remaining minor monoterpene glycosides were negligible or undetected. Glomerular-filtration-based renal excretion was the major elimination pathway of paeoniflorin, which was poorly bound to plasma protein. In rats, the systemic exposure level of paeoniflorin increased proportionally as the dose was increased. Rat lung, heart, and liver exposure levels of paeoniflorin were lower than the plasma level, with the exception of the kidney level, which was 4.3-fold greater than the plasma level; brain penetration was limited by the poor membrane permeability. Due to its significant systemic exposure and appropriate pharmacokinetic profile, as well as previously reported antiseptic properties, paeoniflorin is a promising XueBiJing constituent of therapeutic importance.

Hawaii Literacy Hui Conference, 1997: Changing Lives, Building Communities. [Videotape].

ERIC Educational Resources Information Center

Darling-Hammond, Linda; Holt, Linda

This videotape presents the keynote speeches of the 1997 Hawai'i Literacy Hui conference on the theme of "Changing Lives, Building Communities." Featured in the videotape are two speeches: Linda Darling-Hammond's "The Right To Learn and Teach: Towards Democratic Education," in which she discusses how authentic assessment in the context of the new…

First record of the spider genus Wolongia Zhu, Kim Song, 1997 from India with the description of a new species (Araneae, Tetragnathidae).

PubMed

Malamel, Jobi J; Nafin, Karunnappilli Shamsudheen; Sankaran, Pradeep M; Sebastian, Pothalil A

2018-04-09

Zhu et al. (1997) erected the tetragnathid genus Wolongia to accommodate Wolongia guoi Zhu, Kim Song, 1997 and Wolongia wangi Zhu, Kim Song, 1997 collected from the Sichuan and Shaanxi Provinces in China. In 2009, Ping et al. described Wolongia odontodes from the Gaoligong Mountains and remained with a nominal representation after the erection of the genus. This situation was somewhat rectified by Jin-long Wan Xian-jin Peng (2013) reporting seven new species from the Gaoligong Mountains (Yunnan Province, southwest China). The genus currently with ten nominal species; three are known only from females, while seven are from both sexes (World Spider Catalog 2017). During our survey in Pathiramanal Island we found an undescribed Wolongia species. This is one of the most diverse areas of the Kerala state of Southern India, situated in the Vembanad Lake, a Ramsar Convention (2013) site (wetland of international importance). In this paper, we describe this new species and provide the first report of Wolongia from India.

When Liu Hui Meets Archimedes: Students' Epistemological and Cultural Interpretations of Mathematics

ERIC Educational Resources Information Center

Liu, Po-Hung

2014-01-01

The present study aimed to investigate in what way and to what extent Taiwanese college students' epistemological views of mathematics had evolved during a history-based liberal arts mathematics course titled: "When Liu Hui Meets Archimedes--Development of Eastern and Western Mathematics." The course was designed to help college students…

Untargeted serum metabolomics reveals Fu-Zhu-Jiang-Tang tablet and its optimal combination improve an impaired glucose and lipid metabolism in type II diabetic rats.

PubMed

Tao, Yi; Chen, Xi; Cai, Hao; Li, Weidong; Cai, Baochang; Chai, Chuan; Di, Liuqing; Shi, Liyun; Hu, Lihong

2017-01-01

Fu-Zhu-Jiang-Tang tablet, a six-herb preparation, was proved to show beneficial effects on type II diabetes patients in clinical. This study aims to optimize the component proportion of the six-herb preparation and explore the serum metabolic signatures of type II diabetes rats after treatment with Fu-Zhu-Jiang-Tang tablet and its optimal combination. The component proportion of the preparation was optimized using uniform experimental design and machine learning techniques. Untargeted GC-MS metabolomic experiments were carried out with serum samples from model group and treatment groups. Data were normalized, multivariate and univariate statistical analysis performed and metabolites of interest putatively identified. 23 metabolites were significantly changed by Fu-Zhu-Jiang-Tang tablet treatment and the majority of these were decreased, including various carbohydrates (glucose, mannose, fructose, allose and gluconic acid), unsaturated fatty acids (palmitic acid, 9-octadecenoic acid, oleic acid, arachidonic acid), alanine, valine, propanoic acid, 3-hydroxybutyrate, along with pyrimidine and cholesterol. Increased concentrations of oxalic acid, leucine, glycine, serine, threonine, proline, lysine and citrate were observed. In the optimal combination-fed group, 21 metabolites were significantly affected and strikingly, the magnitudes of changes here were generally much greater than that of Fu-Zhu-Jiang-Tang tablet treated rats. 18 metabolites affected in both groups included various carbohydrates (mannose, glucose, allose, fructose and gluconic acid), unsaturated fatty acids (palmitic acid, 9-octadecenoic acid, oleic acid and arachidonic acid), short-chain fatty acids (oxalic acid, 3-hydroxybutyrate), and amino acids (alanine, valine, leucine, glycine, proline and lysine), as well as pyrimidine. Metabolites exclusively affected in optimal combination treated rat included succinic acid, cysteine and phenylalanine, whilst four metabolites (propanoic acid, citrate

A set of autosomal multiple InDel markers for forensic application and population genetic analysis in the Chinese Xinjiang Hui group.

PubMed

Xie, Tong; Guo, Yuxin; Chen, Ling; Fang, Yating; Tai, Yunchun; Zhou, Yongsong; Qiu, Pingming; Zhu, Bofeng

2018-07-01

In recent years, insertion/deletion (InDel) markers have become a promising and useful supporting tool in forensic identification cases and biogeographic research field. In this study, 30 InDel loci were explored to reveal the genetic diversities and genetic relationships between Chinese Xinjiang Hui group and the 25 previously reported populations using various biostatistics methods such as forensic statistical parameter analysis, phylogenetic reconstruction, multi-dimensional scaling, principal component analysis, and STRUCTURE analysis. No deviations from Hardy-Weinberg equilibrium tests were found at all 30 loci in the Chinese Xinjiang Hui group. The observed heterozygosity and expected heterozygosity ranged from 0.1971 (HLD118) to 0.5092 (HLD92), 0.2222 (HLD118) to 0.5000 (HLD6), respectively. The cumulative probability of exclusion and combined power of discrimination were 0.988849 and 0.99999999999378, respectively, which indicated that these 30 loci could be qualified for personal identification and used as complementary genetic markers for paternity tests in forensic cases. The results of present research based on the different methods of population genetic analysis revealed that the Chinese Xinjiang Hui group had close relationships with most Chinese groups, especially Han populations. In spite of this, for a better understanding of genetic background of the Chinese Xinjiang Hui group, more molecular genetic markers such as ancestry informative markers, single nucleotide polymorphisms (SNPs), and copy number variations will be conducted in future studies. Copyright © 2018 Elsevier B.V. All rights reserved.

CHROMASSI: a therapy advice system based on chrono-massage and acupression using the method of ZiWuLiuZhu.

PubMed

Nguyen, H P; Le, D L; Tran, Q M; Nguyen, V T; Nguyen, N O

1995-01-01

Massage and Acupression have a history of many years of use by the Vietnamese people in the treatment of diseases, and they can give wonderful therapeutic effects in painful syndromes and chronic diseases, etc. On the other hand, some methods of Chrono-Acupuncture based on chronobiological theory and the holistic concept of traditional medicine are studied and applied in clinical applications. This paper presents the therapy advice system based on Chrono-Massage and Acupression using the method of ZiWuLiuZhu called CHROMASSI. The system includes four major parts. Massage and Acupression Teaching: This part can provide the user with some background in Massage and Acupression theory such as the pathology of the meridians, the classification of points and their function, the therapeutic properties of points, the methods of Massage and Acupression (including Pression, Friction, Rubbing, Light Massage, Petrissage, Rolling and Rubbing, Percussion and Vibration), and the direction of the meridians circulation, displaying AcuPoints represented by color pictures of the 12 main meridians and 2 vessels. More than 330 popular AcuPoints are used in the system. Open AcuPoint Calculating: This module can help us to calculate open AcuPoints based on data about days, months, years and hours using the special method of ZiWuLiuZhu. The Points adopted by ZiWuLiuZhu are the Five Shu Points and Source Points including 66 points (all of them are located below the elbows and knees). The effectiveness of these points becomes particularly evident when they are needled or punctured at optimum time intervals. For example, at 9:00 a.m., September 22, 1994, the open Points by the ZiWuLiuZhu method will be the points K2 (Nhien Coc) and K10 (Am Coc). According to the chronotherapeutic method, first we have to pressure (or puncture) the above points in order to attain the sensation RDac KhiS (arrival of energy), then pressure the other treating points as in ordinary Massage and Acupression

[The affinity between Le family of Tong Ren Tang and acu-moxibustion as viewed from Mian xue tang zhen jiu ji cheng (Mian Xuetang's Synthetic Work of Acu-moxibustion)].

PubMed

Huang, L X

2017-11-28

This compilation process of Mian xue tang zhen jiu ji cheng ( Mian Xuetang ' s Synthetic Work of Acu - moxibustion )was quite mysterious, the book's advent coincidentally met with several major historical events which made its value of decoding its historical functions far beyond its academic value. The editor of this book is Le Xianyang, the founder of Tong Ren Tang. While compiling this book, he also made a replica of Ming-Dynasty's Zhengtong bronze statue. More than 200 years later, Le Jingyu, the 12th generation of the Le family revised Ming Tang Tu inherited from his ancestors and engraved Ming Tang Tu on the stone for its standardization. This great achievement of Le family was no less than the recasting of the Tiansheng bronze statue and the reengraving Tong ren shu xue zhen jiu tu jing ( Illustrated Manual of Acupuncture Points of the Bronze Figure ) by support of state power for building the Beijing Imperial Hospital in the eighth year of the Zhengtong reign (1443).

Petroleum systems of Zhu III depression in Pearl River Mouth Basin, South China Sea

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weilin, Zhu; Li Mingbi; Wu Peikang

Zhu III depression is located in the west part of Pearl River Mouth Basin, and covers an area of 11,000 sq km. Until now more than twenty wells have been drilled in the depression and its surrounding area, and all oil-gas fields and oil-gas discoveries are concentrated inside the depression. Integrated study indicates that there are two petroleum systems in Zhu III depression. One is Wenchang - Zhuhai, Zhujiang oil system which is mainly distributed in Wenchang B sag in the southwest part of the depression. Its source rock, the Wenchang formation is mainly composed of dark mudstone of lacustrinemore » facies, with thicknesses up to more than 1000 m. Its reservoir includes tidal sandstone of transitional facies of Zhuhai formation and neritic sandstone of the lower part of Zhujiang formation. Through bounding faults and margin coarse sediment zone, oil generated from the Wenchang formation migrated into overlying sandstone of Zhuhai formation, which was overlaid by mudstone beds of bay facies of Zhuhai formation or neritic facies of Zhujiang formation, and formed oil accumulations. The other system is Enping - Zhuhai gas system, distributed in Wenchang A sag in the northeast part of the depression, whose source rock in the Enping formation deposited in the contracting stage of the lake, dominated by swamp coal measure in lithology and terrestrial plant clastics in kerogen components. The gas generated from Enping formation directly migrated into overlying tidal sandstone of Zhuhai formation and formed gas accumulations. Therefore, exploration in Wenchang A sag in the northeast part of the depression is for gas accumulations, and oil accumulations in Wenchang B sag in the southwest part of the depression, while oil-gas mixed accumulations are likely to be found in the transitional area of two systems.« less

[The Seongho () School's Study of the Ancient Learning () and Its Influence on the Debate about Materia Medica in the Late Joseon Dynasty].

PubMed

Cho, Sung-San

2015-08-01

This study will determine the ways in which the ancient learning (gu xue, ) scholarship of the Seongho School, and its interest in the materia medica (ben cao xue, ) were related during the late Joseon period. The Seongho School centered its studies mainly on classical Chinese texts of the Han (206 BC－AD 220) and pre-Han (?－221 BC) (xian-qin lianghan, ) periods rather than those of the Tang and Song dynasties (618-1279). gu xue scholarship emerged during the Ming dynasty era (1368 －1644) as an alternative to the scholarly trends of the Song dynasty, which were dependent on Zhu Xi's (, 1130－1200) Neo-Confucianism and its interpretation of Han and pre-Han classical Chinese texts. This scholarly trend influenced Korean and Japanese literature, philosophy, and even medicine from the seventeenth through the nineteenth centuries. Focusing on Korean scholarship, we find a great deal of research regarding the influence of gu xue on Korean classical Chinese literature and Confucian philosophy in the late Joseon period; however, no study has examined how this style of scholarship influenced the field of medicine during the same period. This study will investigate how the intellectuals of the Seongho School, who did the most to develop gu xue among Joseon intellectuals, were influenced by this style of scholarship in their study of the materia medica. Jeong Yak-yong (1762－1836), the representative intellectual of the Seongho School, did not focus on complicated metaphysical medical theories, such as the Yin-Yang and Five Elements theory (yin yang wu xing shui, ) or the Five Movements and Six Atmospheres theory (wu yun liu qi shui, ). Instead, his interests lay in the exact diagnoses of diseases and meticulous herbal prescriptions which formed an essential part of the Treatise on Exogenous Febrile Disease (Shang han lun, ) written by Zhang Zhungjing (, 150－219) in the Han dynasty. The Treatise was compatible with the scholarly purpose of gu xue in that they both

[Flipping moxibustion of Hui medicine combined with western medication for rheumatoid arthritis with cold dampness bi syndrome].

PubMed

Wang, Shunji; Ye, Gaxi; Zhang, Yu; Guan, Shuting; Liu, Xiufen; Ren, Wenjing

2017-10-12

To compare the effects of flipping moxibustion of Hui medicine combined with western medication and simple western medication for rheumatoid arthritis with cold dampness bi syndrome. Eighty patients were randomly assigned into an observation group and a control group, 40 cases in each group. Oral methotrexate (1 time a week) and sulfasalazine (twice a day except the day for methotrexate) were used in the two groups. Patients in the observation group were treated with flipping moxibustion of Hui medicine, twice a week. The main acupoints were Shenshu (BL 23), Guanyuan (CV 4), Zusanli (ST 36), Yinlingquan (SP 9), and the matching acupoints were in the meridians related to the disease location. All the treatment was given for continuous 4 weeks. The TCM symptom score, visual analogue scale (VAS) score, blood sedimentation (ESR), rheumatoid factor (RF) and C-reactive protein (CRP) were observed before and after treatment. The effect was evaluated. The total effect rate in the observation group was 95.0% (38/40), which was better than 77.5% (31/40) in the control group ( P <0.05). After treatment, the VAS score, TCM symptom score, RF, ESR, CRP levels decreased in the two groups (all P <0.05), with better effects in the observation group (all P <0.05). The adverse reactions in the observation group were lower than those in the control group. Flipping moxibustion of Hui medicine combined with western medication for rheumatoid arthritis with cold dampness bi syndrome are better than simple western medication, which are safer and more effective.

Measuring health related quality of life (HRQoL) in community and facility-based care settings with the interRAI assessment instruments: development of a crosswalk to HUI3.

PubMed

Hirdes, John P; Bernier, Julie; Garner, Rochelle; Finès, Philippe; Jantzi, Micaela

2018-05-01

Health-related quality of life (HRQoL) measures are of interest because they can be used to describe health of populations and represent a broader health outcome for population health analyses than mortality rates or life expectancy. The most widely used measure of HRQoL for deriving estimates of health-adjusted life expectancy is the Health Utilities Index Mark 3 (HUI3). The HUI3 is available in most national surveys administered by Statistics Canada, and has been used as part of a microsimulation model to examine the impact of neurological conditions over the life course. Persons receiving home care and nursing home services are often not well-represented in these surveys; however, interRAI assessment instruments are now used as part of normal clinical practice in these settings for nine Canadian provinces/territories. Building on previous research that developed a HUI2 crosswalk for the interRAI assessments, the present study examined a new interRAI HRQoL index crosswalked to the HUI3. interRAI and survey data were used to examine the distributional properties of global and domain-specific interRAI HRQoL and HUI3 index scores, respectively. Three populations were considered: well-elderly persons not receiving home care, home care clients and nursing home residents. The mean HUI3 and interRAI HRQoL index global scores declined from independent healthy older persons to home care clients, followed by nursing home residents. For the home care and nursing home populations, the interRAI HRQoL global estimates tended to be lower than HUI3 global scores obtained from survey respondents. While there were some statistically significant age, sex and diagnostic group differences in global scores and within attributes, the most notable differences were between populations from different care settings. The present study provides strong evidence for the validity of the interRAI HRQoL based on comparisons of distributional properties with those obtained with survey data based

RuHe DuiDai WanMei ZhuYi De XueSheng (Working with Perfectionist Students). ERIC Digest.

ERIC Educational Resources Information Center

Brophy, Jere

Perfectionist students are not satisfied with merely doing well or even with doing better than their peers. They are satisfied only if they have done a job perfectly. Problems associated with forms of perfectionism that focus on seeking success are relatively minor, but problems associated with forms of perfectionism that focus on avoiding failure…

[Association of Insulin Resistance and β Cell Function with Lipid Metabolism in Middle-aged and Elderly Hui and Han Populations].

PubMed

Li, Shu-ya; Jiang, Min; Yao, Tian-yu; Cheng, Yu-xuan; Fan, Ya-jie; Liu, Xu-ying; Zhang, Jin-ling; Liu, Lan; Wang, Zhi-zhong; Ma, Yu-ying; Hu, Xue-qin; Wang, Pan-pan; Yu, Jing-jing; Ma, Rong; Huang, Qi

2016-04-01

To explore the association of insulin resistance and β cell function with lipid metabolism in middle-aged and elderly Hui and Han populations. A total of 1000 subjects age over 40 years were recruited from five urban communities in Yinchuan and Wuzhong cities of Ningxia. The composition ratio between Hui and Han nationality was 1:2. A questionnaire-based survey was performed. Physical examinations were carried out to measure the height, body mass, waistline, and hipline. The levels of triglyceride (TG), total cholesterol (TC), blood uric acid (BUA), fasting blood glucose and insulin were measured. The boby mass index (BMI), waist-hip ratio (WHR), and secretion related index including insulin resistance index (IR), insulin sensitivity index (IAI), and beta cell function index (HBCI) were calculated. The BMI, WHR, IAI, HBCI, and the prevalence rate of diabetes in Hui nationality were significantly higher than those in Han nationality (P<0.01). The levels of BUA, fasting blood glucose, TC, and IR in Han nationality were significantly lower than those in Hui nationality (P<0.01). In Hui populations, TG, BMI, WHR, and BUA were positively correlated with IR (r=0.234, r=0.193, r=0.143, and r=0.129, respectively; P<0.01) and were negatively correlated with IAI (r=-0.234, r=-0.193, r=-0.143, r=-0.129, respectively; P<0.01), whereas TC was negatively correlated with HBCI (r=-0.169, P<0.01). In Han populations, TC, TG, BMI, WHR, and BUA were positively correlated with IR (r=0.140, r=0.257, r=0.288, r=0.163, r=0.104, P<0.01) and negatively correlated with IAI (r=-0.140, r=-0.257, r=-0.288, r=-0.163, and r=-0.104, P<0.01), whereas BMI was negatively correlated with HBCI (r=-0.111, P<0.01). After the influential factors such as gender, nationality, and age were adjusted, the TC, TG, BMI, WHR, BUA levels were positively correlated with IR (r=0.109, r=0.256, r=0.253, r=0.139, and r=0.142, P<0.01) and negatively correlated with IAI (r=-0.109, r=-0.256, r=-0.253, r=-0.139, and r=-0

Pollution characteristics and influencing factors of atmospheric particulate matter (PM2.5) in Chang-Zhu-Tan area

NASA Astrophysics Data System (ADS)

Zhang, Yong; Jiang, Wulin

2018-01-01

Using the same time data of PM2.5 concentration and meteorology from May 1st to May 31st in 2013 in Chang-Zhu-Tan area. This paper analyses the variation characteristics of PM2.5 concentration and the correlations between the variation characteristics and meteorological factors. In view of time, the results showed that the 24-h PM2.5 concentration varied with the two peaks and two valleys styles in Chang-Zhu-Tan area. And the daily PM2.5 concentration tends to the instability and great variation characteristics with the multi-peaks and multi-valleys style. In view of space, PM2.5 concentration values of the three cities from high to low are Zhuzhou>Xiangtan>Changsha. For cities and suburbs, PM2.5 concentration values of central towns are greater than that of the suburbs in Changsha and Xiangtan; however, the PM2.5 concentration values of the central town in Zhuzhou are slightly lower than the suburbs. At the same time, the correlation analysis between PM2.5 concentration and meteorological factors showed that the correlation from high to low was the relative air humidity>soil temperature>air temperature>soil humidity> wind velocity>rainfall. Among the above meteorological factors, wind velocity, rainfall, air temperature, soil temperature and soil humidity are negatively correlated with PM2.5 concentration, but the relationship between relative air humidity and PM2.5 concentration is a positive correlation.

[Philological structure of Dan xi shou jing (Danxi's Hand Mirror)].

PubMed

Chen, Yincan; Zhu, Jianping

2015-05-01

Zhu Danxi, one of the four Major Schools of the Jin-Yuan Dynasties, had a lot of works circulated with its authorship in disarray. Part of the works were compiled by his disciples, while others were by his self-taught followers based on prior circulated Danxi's originals, plus some apocryphal so-called Danxi's works circulated posthumously. When sorting out Danxi's Hand Mirror, we found that some of its contents are closely related to Bei ji qian jin yao fang (Essential Prescriptions Worth a Thousand Gold for Emergencies), Qian jin yi fang (Supplements to Qian jin yao fang), Tai ping sheng hui fang (Peaceful Holy Benevolent Prescriptions), Zhu jie shang han lun (Annotated Treatises of Cold Pathogenic Disease), Shang han ming li lun (Elucidation of Cold Pathogenic Disease), Ge zhi yu lun (Treatise of Inquiring the Properties of Things), either by transcription or with an identical origin. By clearing their relationships, it can provide assistance to the research of the philological structure of Danxi's hand Mirror.

Ionic liquid and aqueous two-phase extraction based on salting-out coupled with high-performance liquid chromatography for the determination of seven rare ginsenosides in Xue-Sai-Tong injection.

PubMed

Li, Lan-Jie; Jin, Yong-Ri; Wang, Xiao-Zhong; Liu, Ying; Wu, Qian; Shi, Xiao-Lei; Li, Xu-Wen

2015-09-01

A method of ionic liquid salt aqueous two-phase extraction coupled with high-performance liquid chromatography has been developed for the analysis of seven rare ginsenosides including Rg6 , F4 , 20(S)-Rg3 , 20(R)-Rg3 , Rk3 , Rk1 , and Rg5 in Xue-Sai-Tong injection. The injection was mixed with ionic liquid 1-butyl-3-methylimidazolium bromide aqueous solution, and a mixture was obtained. With the addition of sodium dodecyl sulfate and dipotassium phosphate into the mixture, the aqueous two-phase mixture was formed after ultrasonic treatment and centrifuged. Rare ginsenosides were extracted into the upper phase. To obtain a high extraction factors, various influences were considered systematically, such as the volume of ionic liquid, the category and amount of salts, the amount of sodium dodecyl sulfate, the pH value of system, and the time of ultrasonic treatment. Under the optimal condition, rare ginsenosides in Xue-Sai-Tong injection were enriched and detected, the recoveries of seven rare ginsenosides ranged from 90.05 to 112.55%, while relative standard deviations were lower than 2.50%. The developed method was reliable, rapid and sensitive for the determination of seven rare ginsenosides in the injections. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Hui Malama O Ke Kai: A Positive Prevention-Based Youth Development Program Based on Native Hawaiian Values and Activities

ERIC Educational Resources Information Center

Hishinuma, Earl S.; Chang, Janice Y.; Sy, Angela; Greaney, Malia F.; Morris, Katherine A.; Scronce, Ami C.; Rehuher, Davis; Nishimura, Stephanie T.

2009-01-01

Evaluation of after-school programs that are culturally and place-based and promote positive youth development among minority and indigenous youths has not been widely published. The present evaluation is the first of its kind of an after-school, youth-risk prevention program called Hui Malama O Ke Kai (HMK), that emphasizes Native Hawaiian values…

[Relationship between leaf anatomical structure and heat resistance of 15 Rhododendron cultivars].

PubMed

Shen, Hui Fei; Zhao, Bing; Xu, Jing Jing

2016-12-01

In this study, 17 anatomical structure indexes of 15 Rhododendron cultivars were mea-sured by scanning electron microscope (SEM). Leaf anatomical structure indexes were screened via coefficient of variation, analysis of correlation and hierarchical cluster analysis, and comprehensive evaluation on heat resistance for each cultivar was conducted by the subordinate function. The results showed that the leaves of Rhododendron cultivars were typical bifacial leaf and the epidermal anticlinal walls showed slightly sinuate. The stomata only distributed in the lower epidermis and the shape was ruleless. The anatomical structure indexes all reached a significant level difference among 15 cultivars (P<0.01), except for lower epidermis thickness (P<0.05). Thickness of lamina corneum, stomatal density, stomatal width, the thickness palisade tissue and looseness of leaf spongy tissue were the main factors related to the hardness, while other indexes, such as stomatal length, stoma aperture, stomatal opening, length and thickness of upper epidermis, length and thickness of lower epidermis, thickness of spongy tissue, the ratio of the palisade tissue to spongy tissue, tightness of leaf palisade tissue, leaf thickness and media thickness didn't show much effect on heat resistance. There were some differences among 15 cultivars in heat resistance, and the order was Rhododendron 'Song Jiang Da Tao Hong' > Rhododendron 'Zhuang Yuan Hong' > Rhododendron 'Lv Se Guang Hui' > Rhododendron 'Fen Zhen Zhu' > Rhododendron 'Wai Guo Hong' > Rhododendron 'Lan Yin' > Rhododendron 'Bi Zhi' >Rhododendron 'Da He Zhi Chun' > Rhododendron 'Guo Qi Hong' > Rhododendron 'Yu Ling Long' > Rhododendron 'Hong Shan Hu' > Rhododendron 'Ning Bo Hong' > Rhododendron 'Tao Ban Zhu Sha' > Rhododendron 'Ai Ding Bao' > Rhododendron 'Liu Qiu Hong'. According to the heat hardiness, the cultivars could be divided into 4 groups: R. 'Song Jiang Da Tao Hong', R. 'Zhuang Yuan Hong' and R. 'Lv Se Guang Hui' with high heat

Traditional Chinese medicine compound ShengJinRunZaoYangXue granules for treatment of primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled clinical trial.

PubMed

Hu, Wei; Qian, Xian; Guo, Feng; Zhang, Miaojia; Lyu, Chengyin; Tao, Juan; Gao, Zhong'en; Zhou, Zhengqiu

2014-01-01

Traditional Chinese medical treatment of primary Sjögren's syndrome has advantages over Western medicine in terms of fewer side effects and improved patient conditions. This study was a multicenter, randomized, double-blind, placebo-controlled clinical trial of the efficacy and safety of ShengJinRunZaoYangXue granules for the treatment of primary Sjögren's syndrome, including the symptoms of dry mouth and dry eye. We undertook a 6-week, double-blind, randomized trial involving 240 patients with primary Sjögren's syndrome at five centers in East China. A computer-generated randomization schedule assigned patients at a 2:1 ratio to receive either ShengJinRunZaoYangXue granules or placebo once daily. Patients and investigators were blinded to treatment allocation. The primary endpoints were the salivary flow rate, Schirmer test results, and sugar test results. Intention-to-treat and per-protocol analyses were performed. All 240 patients were randomly allocated to either the treatment group (n = 160, ShengJinRunZaoYangXue granules) or placebo group (n = 80) and were included in the intention-to-treat analysis. After program violation and loss to follow-up, a total of 199 patients were included in the per-protocol analysis. At six week, intention-to-treat and per-protocol analyses of the left-eye Schirmer I test results showed an improved difference of 1.36 mm/5 min (95% CI: 0.03 to 2.69 mm/5 min) and 1.35 mm/5 min (95% CI: 0.04 to 2.73 mm/5 min), respectively, and those of the right-eye Schirmer I test results showed an improved difference of 1.12 mm/5 min (95% CI: 0.02 to 2.22 mm/5 min) and 1.12 mm/5 min (95% CI: -0.02 to 2.27 mm/5 min), respectively. There was no significant difference between the two groups before treatment. After treatment, the between-group and within-group before-and-after paired comparison results were statistically significant (P < 0.05). Intention-to-treat and per-protocol analyses showed an improved salivary flow rate by 0.04 ml/15 min (95

Arsenic-contaminated cold-spring water in mountainous areas of Hui County, Northwest China: a new source of arsenic exposure.

PubMed

Zhang, Qiang; Zheng, Quanmei; Sun, Guifan

2011-11-15

Although pump-well is the primary drinking water source in rural areas of China, there are still 8.4% of villages reliant on cold-spring. In this study, a survey of arsenic concentration in cold-springs and pump-wells was carried out in Hui County, Northwest China. A total of 352 drinking water samples, including 177 cold-springs and 175 pump-wells, were collected. The maximum arsenic concentrations in cold-springs and pump-wells were 0.482 mg/L and 0.067 mg/L, respectively. We found that 15.8% (28) of total cold-springs and 1.1% (2) of total pump-wells had arsenic concentrations exceeding the maximum allowable concentration of arsenic in drinking water of rural China (0.05 mg/L). Our findings show that 5 cold spring-contaminated villages are located in the mountainous areas of Hui County and 2224 inhabitants may be at risk of high arsenic exposure. This paper indicates that arsenic contamination of cold-springs may be more serious than expected in mountainous areas of Northwest China and extensive surveys and epidemiological studies should be carried out to investigate the potential contaminated areas and affected population. Copyright © 2011 Elsevier B.V. All rights reserved.

Appendix I1-2 to Wind HUI Initiative 1: Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

John Zack; Deborah Hanley; Dora Nakafuji

This report is an appendix to the Hawaii WindHUI efforts to dev elop and operationalize short-term wind forecasting and wind ramp event forecasting capabilities. The report summarizes the WindNET field campaign deployment experiences and challenges. As part of the WindNET project on the Big Island of Hawaii, AWS Truepower (AWST) conducted a field campaign to assess the viability of deploying a network of monitoring systems to aid in local wind energy forecasting. The data provided at these monitoring locations, which were strategically placed around the Big Island of Hawaii based upon results from the Oahu Wind Integration and Transmission Studymore » (OWITS) observational targeting study (Figure 1), provided predictive indicators for improving wind forecasts and developing responsive strategies for managing real-time, wind-related system events. The goal of the field campaign was to make measurements from a network of remote monitoring devices to improve 1- to 3-hour look ahead forecasts for wind facilities.« less

[Application and case analysis on the problem-based teaching of Jingluo Shuxue Xue (Science of Meridian and Acupoint) in reference to the team oriented learning method].

PubMed

Ma, Ruijie; Lin, Xianming

2015-12-01

The problem based teaching (PBT) has been the main approach to the training in the universities o the world. Combined with the team oriented learning method, PBT will become the method available to the education in medical universities. In the paper, based on the common questions in teaching Jingluo Shuxue Xue (Science of Meridian and Acupoint), the concepts and characters of PBT and the team oriented learning method were analyzed. The implementation steps of PBT were set up in reference to the team oriented learning method. By quoting the original text in Beiji Qianjin Yaofang (Essential recipes for emergent use worth a thousand gold), the case analysis on "the thirteen devil points" was established with PBT.

Molecular diversity analysis of Tetradium ruticarpum (WuZhuYu) in China based on inter-primer binding site (iPBS) markers and inter-simple sequence repeat (ISSR) markers.

PubMed

Xu, Jing-Yuan; Zhu, Yan; Yi, Ze; Wu, Gang; Xie, Guo-Yong; Qin, Min-Jian

2018-01-01

"Wu zhu yu", which is obtained from the dried unripe fruits of Tetradium ruticarpum (A. Jussieu) T. G. Hartley, has been used as a traditional Chinese medicine for treatment of headaches, abdominal colic, and hypertension for thousands of years. The present study was designed to assess the molecular genetic diversity among 25 collected accessions of T. ruticarpum (Wu zhu yu in Chinese) from different areas of China, based on inter-primer binding site (iPBS) markers and inter-simple sequence repeat (ISSR) markers. Thirteen ISSR primers generated 151 amplification bands, of which 130 were polymorphic. Out of 165 bands that were amplified using 10 iPBS primers, 152 were polymorphic. The iPBS markers displayed a higher proportion of polymorphic loci (PPL = 92.5%) than the ISSR markers (PPL = 84.9%). The results showed that T. ruticarpum possessed high loci polymorphism and genetic differentiation occurred in this plant. The combined data of iPBS and ISSR markers scored on 25 accessions produced five clusters that approximately matched the geographic distribution of the species. The results indicated that both iPBS and ISSR markers were reliable and effective tools for analyzing the genetic diversity in T. ruticarpum. Copyright © 2018 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

A rapid UFLC-MS/MS method for simultaneous determination of formononetin, cryptotanshinone, tanshinone IIA and emodin in rat plasma and its application to a pharmacokinetic study of Bu Shen Huo Xue formula.

PubMed

Xu, Yuping; Huang, Kexin; Pan, Yu; Wang, Xianqin; Yan, Pengcheng; Ren, Yiping; Xiang, Zheng

2013-08-01

Bu Shen Huo Xue formula (BSHX) is a traditional Chinese medicine prescription used for clinical treatment of chronic kidney diseases. A rapid and selective Ultra fast liquid chromatography with tandem mass spectrometry (UFLC-MS/MS) method was developed for simultaneous determination of four bioactive components of BSHX including formononetin, cryptotanshinone, tanshinone IIA, and emodin in control and unilateral ureteral obstruction (UUO) model rat plasma for the first time. Atorvastatin was used as the internal standard (IS). Plasma samples were extracted by liquid-liquid extraction with ethyl acetate. The chromatographic separation was carried out on a Shim-pack XR-ODS III column with a gradient mobile phase consisting of acetonitrile and 0.1% formic acid. The detection was performed on a triple-quad tandem mass spectrometer by multiple reaction monitoring (MRM) via electrospray ionization (ESI) source with positive ionization mode for formononetin, cryptotanshinone, tanshinone IIA, and negative mode for emodin. The method was linear for four analytes over the range of investigated concentration with all coefficients of determination (R(2)) greater than 0.9938. The lower limits of quantification (LLOQ) for formononetin, cryptotanshinone, tanshinone IIA, and emodin were defined as 0.3, 0.5, 1.5, and 0.3ng/mL, respectively. The rapid and sensitive method was fully validated and successfully applied to the pharmacokinetic study of formononetin, cryptotanshinone, tanshinone IIA and emodin in rats following oral administration of Bu Shen Huo Xue formula. Copyright © 2013 Elsevier B.V. All rights reserved.

Surface-enhanced Raman scattering study of the healing of radial fractures treated with or without Huo-Xue-Hua-Yu decoction therapy

NASA Astrophysics Data System (ADS)

Chen, Weiwei; Huang, Hao; Chen, Rong; Feng, Shangyuan; Yu, Yun; Lin, Duo; Lin, Jia

2014-11-01

This study aimed to assess, through surface-enhanced Raman scattering (SERS) spectroscopy, the incorporation of calcium hydroxyapatite (CHA ~960 cm-1) and other biochemical substances in the repair of complete radial fractures in rabbits treated with or without Huo-Xue-Hua-Yu decoction (HXHYD) therapy. A total of 18 rabbits with complete radial fractures were randomly divided into two groups; one group was treated with HXHYD therapy and the other without therapy acted as a control. The animals were sacrificed at 15, 30 and 45 d after surgery. Specimens were routinely prepared for SERS measurement and high quality SERS spectra from a mixture of bone tissues and silver nanoparticles were obtained. The mineral-to-matrix ratios from the control and treated groups were calculated. Results showed that both deposition content of CHA measured by SERS spectroscopy and the mineral-to-matrix ratio in the treated group were always greater than those of the control group during the experiment, demonstrating that HXHYD therapy is effective in improving fracture healing and that SERS spectroscopy might be a novel tool to assess fracture healing.

Identification and phylogenetic analysis of a sheep pox virus isolated from the Ningxia Hui Autonomous Region of China.

PubMed

Zhu, X L; Yang, F; Li, H X; Dou, Y X; Meng, X L; Li, H; Luo, X N; Cai, X P

2013-05-14

An outbreak of sheep pox was investigated in the Ningxia Hui Autonomous Region in China. Through immunofluorescence testing, isolated viruses, polymerase chain reaction identification, and electron microscopic examination, the isolated strain was identified as a sheep pox virus. The virus was identified through sequence and phylogenetic analysis of the P32 gene, open reading frame (ORF) 095, and ORF 103 genes. This study is the first to use the ORF 095 and ORF 103 genes as candidate genes for the analysis of sheep pox. The results showed that the ORF 095 and ORF 103 genes could be used for the genotyping of the sheep pox virus.

Comment on “Time-changed geometric fractional Brownian motion and option pricing with transaction costs” by Hui Gu et al.

NASA Astrophysics Data System (ADS)

Guo, Zhidong; Song, Yukun; Zhang, Yunliang

2013-05-01

The purpose of this comment is to point out the inappropriate assumption of “3αH>1” and two problems in the proof of “Theorem 3.1” in section 3 of the paper “Time-changed geometric fractional Brownian motion and option pricing with transaction costs” by Hui Gu et al. [H. Gu, J.R. Liang, Y. X. Zhang, Time-changed geometric fractional Brownian motion and option pricing with transaction costs, Physica A 391 (2012) 3971-3977]. Then we show the two problems will be solved under our new assumption.

Using Detrital Zircon Geochronology to Constrain Paleogene Provenance and Its Relationship to Rifting in the Zhu 1 Depression, Pearl River Mouth Basin, South China Sea

NASA Astrophysics Data System (ADS)

Wang, Wei; Ye, Jiaren; Bidgoli, Tandis; Yang, Xianghua; Shi, Hesheng; Shu, Yu

2017-11-01

Paleogene syn-rift successions in the South China Sea are poorly understood and systematic provenance analysis, which could provide clues to their history, is lacking. Here we report 409 new concordant U-Pb ages from detrital zircons separated from the Paleogene Wenchang, Enping, and Zhuhai formations in the Zhu 1 depression, Pearl River Mouth Basin. The new data, combined with the published age data from the region, document changes in the provenance of syn-rift successions. Detrital zircons from the Eocene Wenchang Formation are unimodal, with Jurassic-Cretaceous (180-80 Ma) ages making up >80% of grains. The ages are consistent with the geochronology of intrabasinal highs, dominated by igneous rocks emplaced during the Yanshanian orogeny, and suggest local provenance. By contrast, detrital zircons from the upper Eocene to lower Oligocene Enping Formation form three well-recognized age-clusters, with peaks at 150, 254, and 438 Ma that match documented tectonomagmatism in South China Block (SCB). Combined with increasing numbers of Precambrian zircons, the data suggest increasing influence of regional provenance of the SCB. Similar age peaks are also recognized from the limited number of zircons analyzed from the upper Oligocene Zhuhai Formation and comparability with modern shelf and river sediment indicates the unit was mainly sourced from the SCB and likely transported by a paleo-Pearl River. We infer that the change in provenance, from local uplifts within the Zhu 1 to the SCB, is related to distinct phases of PRMB rift development; however, later changes are best explained by SCB drainage evolution.

[Study on the relationship between WBC count levels and type 2 diabetes mellitus in Hui and Han nationality of Ningxia].

PubMed

Liu, Yuan; He, Qunpeng; Chen, Lijun; Liu, Herong; Zhao, Chuan; Song, Hui

2015-05-01

To analyze the relationship between WBC count levels and type 2 diabetes mellitus in Hui and Han nationality of Ningxia. Using the method of case-control study, people of regional organizations and institutions aged 20 - 60 who received medical health checkup and endocrine patients in General Hospital of Ningxia Medical College and WuZhong city People's Hospital from October 2011 to October 2012 were enrolled in the study. According to the inclusion and exclusion criteria of T2DM patients and control groups, with gender, ethnic and age are not more than 3 years old cases and controls of matching, the T2DM group (case group) of 351 cases and non-T2DM group (control group) of 655 cases were determined. These subjects underwent questionnaire investigation, understand first, like the situation, the way of life, disease and medication history, family history. Physical examination: including height, weight, waist circumference (WC), systolic blood pressure (SBP) and diastolic blood pressure (DBP), and according to the height and weight to calculate body mass index (BMI), and laboratory tests, triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL-C), low density lipoprotein (LDL-C), blood uric acid (UA ), nmda aminotransferase ( AST) , alanine aminotransferase (ALT), blood biochemical indexes. Results Diabetes group of average age (50.28 + 8.32), 194 patients with male, (55.27%), 157 patients with female (44.73%) and control group in average age (50. 17 + 7. 14) , including 337 men (51.45% ) and 318 women (48.55%). Average age, gender, the proportion between the two groups had no statistical significance of difference. The white blood cell value of T2DM group (6.66 x 10(9) ± 1.61 x 10(9)/L) was higher than that of non-T2DM group (6.11 x 10(9) ± 1.49 x 10(9)/L), there was a significant difference (t = -5.430, P < 0.01); Comparing the mean value of white blood cell of Hui (6.459 x 10(9) ± 1.45 x 10(9)/L) and Han nationality (6.169 x 10(9) ± 1.63 x 10

Hui Malama o ke Kai: mobilizing to prevent youth violence and substance use with passion, common goals, and culture.

PubMed

Akeo, Nani P; Bunyan, Eric S; Burgess, Kaui N; Eckart, David R; Evensen, Shirley L; Hirose-Wong, Shannon M; Majit-Gorion, Sharon S; Takeshita, Carl K; Takeshita, Irene K; Vasconcellos, Carl G

2008-03-01

The goal of the Hui Malama o ke Kai project was the development of a community-based youth program that supported the prevention of youth violence and substance use among 5th- and 6th-grade students from a predominantly Hawaiian community. This program's development included engaging with a variety of community partners and mobilizing parents through the youths' cultural development. Recommendations for working with Hawaiians and other indigenous peoples include having program evaluators work more intimately with program participants and developing program components that address ethnic identity and family engagement. In doing so, youth programs with indigenous peoples can also galvanize small communities that are coping with destructive social concerns.

Detection and identification of Huo-Xue-Hua-Yu decoction (HXHYD) using surface-enhanced Raman scattering (SERS) spectroscopy and multivariate analysis

NASA Astrophysics Data System (ADS)

Chen, Weiwei; Lin, Jia; Chen, Rong; Feng, Shangyuan; Yu, Yun; Lin, Duo; Huang, Meizhen; Shi, Hong; Huang, Hao

2015-04-01

We have evaluated the capabilities of surface-enhanced Raman scattering (SERS) technology for analyzing two Huo-Xue-Hua-Yu decoctions (HXHYDs) prepared according to different prescriptions. The aim of this study was to evaluate the relevance of SERS technology applied to decoction of traditional Chinese medicines (TCM). HXHYD I was prepared according to the original prescription; the same preparation method was used for the HXHYD II, except for the crudeweight ratio described in the original prescription. There was no Raman signal in conventional Raman spectra of HXHYDs. Silver nanoparticles were directly mixed with HXHYDs to enhance the Raman scattering of biochemical constituents, and high quality SERS spectra were obtained. Significant differences in SERS spectra between HXHYD I and II can be observed, which showed special changes in the percentage of biochemical constituents in different decoctions. Principal components analysis (PCA) combined with linear discriminant analysis (LDA) were employed to generate diagnostic algorithms for classification of SERS spectra of two HXHYDs, and showed that a diagnostic accuracy of 100% can be achieved. This work demonstrated that the SERS technique has potential for spectral characteristic detection for decoction of TCM with high sensitivity, and that this technique, combined with PCA-LDA, can be used for quality control of the extracted decoction of TCM and production management of Chinese herbal preparations.

Traduire encore Bertin aujourd'hui : pourquoi faire ? Les nouvelles faces cachées de la Sémiologie Graphique

NASA Astrophysics Data System (ADS)

Dhieb, Mohsen

2018-05-01

La « Sémiologie Graphique » de Bertin est un ouvrage majeur de la cartographie contemporaine. Cependant, dès sa parution en 1967, cet ouvrage a suscité autant d'intérêt que de méfiance : l'ouvrage n'était pas dans le « moule » de la littérature cartographique en vigueur. Pourtant, si plusieurs de ses principes et concepts fondateurs ont été adoptés, plusieurs autres ne sont pas bien passés ou n'ont pas été mis en pratique. Il y a comme un fossé entre certains énoncés théoriques de l'ouvrage et leur mise en pratique. Certaines affirmations de Bertin peuvent paraître obsolètes aujourd'hui à l'heure du numérique, comme la non prise en compte de l'aspect dynamique ou interactif de la carte. L'avènement récent des SIG, de la géomatique et des systèmes de Cartographie Assistée par Ordinateur a relégué les vieilles méthodes de traitement graphique de l'information au second rang. Dès lors pourquoi traduire encore aujourd'hui, à l'heure du numérique, la « Sémiologie Graphique » ? Justement, d'abord, parce que certains principes restent, en substance, peu connus ; plusieurs aspects demeurent encore à explorer ; certaines méthodes et techniques manuelles délaissées peuvent être revisitées et remises en marche grâce à la visualisation ; des innovations n'ont pas été expérimentées ou implémentées par les moyens numériques. Dans le monde arabe, peu de recherches se sont imprégnées de sémiologie graphique. Lors de la traduction de l'ouvrage en arabe, des points restés obscurs ont été décelés. Ce sont ces quelques idées et réflexions qui nous ont poussés à revivre cette formidable aventure.

[Carbon sequestration status of forest ecosystems in Ningxia Hui Autonomous Region].

PubMed

Gao, Yang; Jin, Jing-Wei; Cheng, Ji-Min; Su, Ji-Shuai; Zhu, Ren-Bin; Ma, Zheng-Rui; Liu, Wei

2014-03-01

Based on the data of Ningxia Hui Autonomous Region forest resources inventory, field investigation and laboratory analysis, this paper studied the carbon sequestration status of forest ecosystems in Ningxia region, estimated the carbon density and storage of forest ecosystems, and analyzed their spatial distribution characteristics. The results showed that the biomass of each forest vegetation component was in the order of arbor layer (46.64 Mg x hm(-2)) > litterfall layer (7.34 Mg x hm(-2)) > fine root layer (6.67 Mg x hm(-2)) > shrub-grass layer (0.73 Mg x hm(-2)). Spruce (115.43 Mg x hm(-2)) and Pinus tabuliformis (94.55 Mg x hm(-2)) had higher vegetation biomasses per unit area than other tree species. Over-mature forest had the highest arbor carbon density among the forests with different ages. However, the young forest had the highest arbor carbon storage (1.90 Tg C) due to its widest planted area. Overall, the average carbon density of forest ecosystems in Ningxia region was 265.74 Mg C x hm(-2), and the carbon storage was 43.54 Tg C. Carbon density and storage of vegetation were 27.24 Mg C x hm(-2) and 4.46 Tg C, respectively. Carbon storage in the soil was 8.76 times of that in the vegetation. In the southern part of Ningxia region, the forest carbon storage was higher than in the northern part, where the low C storage was mainly related to the small forest area and young forest age structure. With the improvement of forest age structure and the further implementation of forestry ecoengineering, the forest ecosystems in Ningxia region would achieve a huge carbon sequestration potential.

The traditional Chinese medicine prescription patterns for migraine patients in Taiwan: a population-based study.

PubMed

Chang, Yu-Yun; Tsai, Yueh-Ting; Lai, Jung-Nien; Yeh, Chia-Hao; Lin, Shun-Ku

2014-02-12

Traditional Chinese medicine (TCM), when given for symptom relief, has gained widespread popularity among migraine patients. The aim of this study is to analyze the utilization of TCM among migraine patients in Taiwan. The usage, frequency of service, and the Chinese herbal products prescribed for migraine were evaluated using a representative sample of one million subjects selected at random from the 22 million beneficiaries of the National Health Insurance scheme of Taiwan. Overall, 89.3% (N=12,827) migraine patients utilized TCM and 24.2% of them sought TCM with the intention of treating their migraine-related symptoms. Migraine patients who are living in urban area and those with an episodic migraine pattern (<15 days/month) (aOR=3.18, 95% CI: 2.75-3.67) were more likely to be TCM users than those living in a rural area and those who suffered from chronic migraine (≥15 days/month) (aOR=1.00). Overall, 81.2% of TCM visits involved the prescription of a Chinese herbal remedy or remedies and Chuan-Xiong-Cha-Tiao-San, Jia-Wei-Xiao-Yao-San, Ge-Gen-Tang, Xue-Fu-Zhu-Yu-Tang, Ban-Xia-Bai-Zhu-Tian-Ma-Tang, Qing-Shang-Juan-Tong-Tang, Xiao-Chai-Hu-Tang, Tian-Ma-Gou-Teng-Yin, Bu-Zhong-Yi-Qi-Tang, and Tian-Wang-Bu-Xin-Dan were the ten most frequently prescribed formula for treating migraine based on syndrome differentiation. Chuan-Xiong-Cha-Tiao-San, which contains sedative and anti-inflammatory agents, is the most commonly prescribed Chinese herbal formula for the treatment of migraine-related phenomena. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Effect of Chinese herbal medicine on stroke patients with type 2 diabetes.

PubMed

Tsai, Fuu-Jen; Ho, Tsung-Jung; Cheng, Chi-Fung; Liu, Xiang; Tsang, Hsinyi; Lin, Ting-Hsu; Liao, Chiu-Chu; Huang, Shao-Mei; Li, Ju-Pi; Lin, Cheng-Wen; Lin, Jaung-Geng; Lin, Jung-Chun; Lin, Chih-Chien; Liang, Wen-Miin; Lin, Ying-Ju

2017-03-22

Complications of type 2 diabetes (T2D) include stroke, which is a cerebrovascular disturbance characterized by reduced blood flow in the brain, leading to death or physical disability. Chinese herbal medicine (CHM) has been widely used in ancient China for the treatment of diabetes and stroke by supplementing Qi and activating blood circulation. This study aimed to investigate the frequencies and patterns of CHM treatment for stroke patients with T2D and the outcomes of long-term use in Taiwan. We identified 3079 stroke patients (ICD-9-CM: 430-438) with T2D. We allocated 618 stroke patients, matched for age, gender, and T2D-to-stroke duration, to both CHM and non-CHM groups. Chi-square test, conditional multivariable logistic regression, Kaplan-Meier method, and the log-rank test were used in this study. The CHM group was characterized by more cases of chronic obstructive pulmonary disease, ulcer disease, hyperlipidemia, tobacco use, and higher income. The cumulative survival probability was higher in the CHM group (P<0.001, log rank test); after adjusting for comorbidities, income, and urbanization level, this group also exhibited a lower mortality hazard ratio (0.37, 95% confidence interval [0.25-0.55]). Shu-Jing-Huo-Xue-Tang, Xue-Fu-Zhu-Yu-Tang, and Du-Huo-Ji-Sheng-Tang; and Dan-Shen, Niu-Xi, and Yan-Hu-Suo represented the top three formulas and herbs, respectively. The use of CHM as adjunctive therapy may improve the overall survival (OS) of stroke patients with T2D. The list of the comprehensive herbal medicines that they used might be useful in future large-scale, randomized clinical investigations of agent effectiveness, safety, and potential interactions with conventional treatments in stroke patients with T2D. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

Impact of anthropogenic and natural environmental changes on Echinococcus transmission in Ningxia Hui Autonomous Region, the People’s Republic of China

PubMed Central

2012-01-01

Echinococcus transmission is known to be affected by various environmental factors, which may be modified by human influence or natural events including global warming. Considerable population growth in the last fifty years in Ningxia Hui Autonomous Region (NHAR), the People’s Republic of China (PRC), has led to dramatic increases in deforestation and modified agricultural practices. In turn, this has resulted in many changes in the habitats for the definitive and intermediate hosts of both Echinococcus granulosus and E. multilocularis, which have increased the risks for transmission of both parasites, affecting echinococcosis prevalence and human disease. Ecological environmental changes due to anthropogenic activities and natural events drive Echinococcus transmission and NHAR provides a notable example illustrating how human activity can impact on a parasitic infection of major public health significance. It is very important to continually monitor these environmental (including climatic) factors that drive the distribution of Echinococcus spp. and their impact on transmission to humans because such information is necessary to formulate reliable future public health policy for echinococcosis control programs and to prevent disease spread. PMID:22827890

Kai Zhu | NREL

Science.gov Websites

., "Long-range hot-carrier transport in hybrid perovskites visualized by ultrafast microscopy," perovskites for optoelectronic and electronic applications," Chem. Soc. Rev. 45, 655-689 (2016). Yang, M

[Comparative study of theoretical literature on cold pathogenic disease in Wai tai mi yao fang (Arcane Essentials from the Imperial Library) and Tai ping sheng hui fang (Taiping Holy Prescriptions for Universal Relief)].

PubMed

Zhang, Huirui; Liang, Yongxuan

2014-09-01

In the Wai tai mi yao fang (Arcane Essentials from the Imperial Library) compiled in 752, its portion on cold pathogenic disorders embodies the achievements before the mid Tang Dynasty, whereas that in the Tai ping sheng hui fang (Taiping Holy Prescriptions for Universal Relief), compiled in 992 embodies those before the early Song Dynasty. Comparison on the theory of cold disorders in both books reveal that, during the 2 centuries period from mid Tang to early Song Dynasties, the texts as a carrier for the transmission of such theory in both show no distinct changes, but only with minor revisions and improvements.

Impact of "Grain to Green" Programme on echinococcosis infection in Ningxia Hui Autonomous Region of China.

PubMed

Cleary, Eimear; Barnes, Tamsin S; Xu, Yangyang; Zhao, Hengbo; Clements, Archie C A; Gray, Darren J; McManus, Donald P; Atkinson, Jo-An M; Williams, Gail M; Yang, YuRong

2014-10-15

Cystic echinococcosis (CE) is endemic among the human population of Xiji County, Ningxia Hui Autonomous Region, China, where the prevalence is estimated to be between 2.2% and 3.6%. Government-run sheep abattoirs in Xiji County have closed in recent years and, as a consequence, slaughter is carried out mostly at rural market places. The market place in Xinglong Township, Xiji County, is home to an increasing number of stray dogs and the lack of government control over slaughter practices potentially favours Echinococcus granulosus transmission. A survey of sheep, goats and cattle reared in Xiji County was conducted in Xinglong Market and Xinglong Township to determine prevalence and transmission dynamics of E. granulosus infection. The liver and lungs of all livestock aged one year and older were examined macroscopically post mortem; visual examination and palpation of organs determined overall prevalence of E. granulosus. Cysts consistent in appearance with E. granulosus were observed in 2/184 sheep (prevalence 1.0%) and 1/55 of the cattle examined (prevalence 1.8%); 0/13 goats were found to be infected. However, microscopic examination of these suspected cysts failed to confirm these samples as E. granulosus, giving a prevalence of confirmed infection of zero percent in all three species. The prevalence of liver fluke was 61.3% in sheep and 12.7% in cattle with a significant difference between males and females (p ≤ 0.001). Considering the high prevalence of echinococcosis in the local human population, the absence of CE observed among commercially slaughtered livestock was surprising. Several explanations for this discrepancy and their implications are proposed. Copyright © 2014 Elsevier B.V. All rights reserved.

Enterobacter xiangfangensis sp. nov., isolated from Chinese traditional sourdough, and reclassification of Enterobacter sacchari Zhu et al. 2013 as Kosakonia sacchari comb. nov.

PubMed

Gu, Chun Tao; Li, Chun Yan; Yang, Li Jie; Huo, Gui Cheng

2014-08-01

A Gram-stain-negative bacterial strain, 10-17(T), was isolated from traditional sourdough in Heilongjiang Province, China. The bacterium was characterized by a polyphasic approach, including 16S rRNA gene sequence analysis, RNA polymerase β subunit (rpoB) gene sequence analysis, DNA gyrase (gyrB) gene sequence analysis, initiation translation factor 2 (infB) gene sequence analysis, ATP synthase β subunit (atpD) gene sequence analysis, fatty acid methyl ester analysis, determination of DNA G+C content, DNA-DNA hybridization and an analysis of phenotypic features. Strain 10-17(T) was phylogenetically related to Enterobacter hormaechei CIP 103441(T), Enterobacter cancerogenus LMG 2693(T), Enterobacter asburiae JCM 6051(T), Enterobacter mori LMG 25706(T), Enterobacter ludwigii EN-119(T) and Leclercia adecarboxylata LMG 2803(T), having 99.5%, 99.3%, 98.7%, 98.5%, 98.4% and 98.4% 16S rRNA gene sequence similarity, respectively. On the basis of polyphasic characterization data obtained in the present study, a novel species, Enterobacter xiangfangensis sp. nov., is proposed and the type strain is 10-17(T) ( = LMG 27195(T) = NCIMB 14836(T) = CCUG 62994(T)). Enterobacter sacchari Zhu et al. 2013 was reclassified as Kosakonia sacchari comb. nov. on the basis of 16S rRNA, rpoB, gyrB, infB and atpD gene sequence analysis and the type strain is strain SP1(T)( = CGMCC 1.12102(T) = LMG 26783(T)). © 2014 IUMS.

WenTong HuoXue Cream Can Inhibit the Reduction of the Pain-Related Molecule PLC-β3 in the Dorsal Root Ganglion of a Rat Model of Diabetic Peripheral Neuropathy

PubMed Central

Feng, Chengcheng; Xu, Lijuan; Guo, Shiyun; Chen, Qian; Shen, Yuguo; Zang, Deng

2018-01-01

WenTong HuoXue Cream (WTHX-Cream) has been shown to effectively alleviate clinical symptoms of diabetic peripheral neuropathy (DPN). This study investigated the gene and protein expression of the pain-related molecule PLC-β3 in the dorsal root ganglion (DRG) of DPN rats. 88 specific pathogen-free male Wistar rats were randomly divided into placebo (10 rats) and DPN model (78 rats) groups, and the 78 model rats were used to establish the DPN model by intraperitoneal injection of streptozotocin and were then fed a high-fat diet for 8 weeks. These rats were randomly divided into the model group, the high-, medium-, and low-dose WTHX-Cream + metformin groups, the metformin group, the capsaicin cream group, and the capsaicin cream + metformin group. After 4 weeks of continuous drug administration, the blood glucose, body weight, behavioral indexes, and sciatic nerve conduction velocity were measured. The pathological structure of the DRG and the sciatic nerve were observed. PLC-β3 mRNA and protein levels in the DRG of rats were measured. Compared with the model group, the high-dose WTHX-Cream group showed increased sciatic nerve conduction velocity, improved sciatic nerve morphological changes, and increased expression of PLC-β3 mRNA and protein in the DRG. This study showed that WTHX-Cream improves hyperalgesia symptoms of DPN by inhibiting the reduction of PLC-β3 mRNA and protein expression in the diabetic DRG of DPN rats. PMID:29599806

WenTong HuoXue Cream Can Inhibit the Reduction of the Pain-Related Molecule PLC-β3 in the Dorsal Root Ganglion of a Rat Model of Diabetic Peripheral Neuropathy.

PubMed

Feng, Chengcheng; Xu, Lijuan; Guo, Shiyun; Chen, Qian; Shen, Yuguo; Zang, Deng; Ma, Li

2018-01-01

WenTong HuoXue Cream (WTHX-Cream) has been shown to effectively alleviate clinical symptoms of diabetic peripheral neuropathy (DPN). This study investigated the gene and protein expression of the pain-related molecule PLC- β 3 in the dorsal root ganglion (DRG) of DPN rats. 88 specific pathogen-free male Wistar rats were randomly divided into placebo (10 rats) and DPN model (78 rats) groups, and the 78 model rats were used to establish the DPN model by intraperitoneal injection of streptozotocin and were then fed a high-fat diet for 8 weeks. These rats were randomly divided into the model group, the high-, medium-, and low-dose WTHX-Cream + metformin groups, the metformin group, the capsaicin cream group, and the capsaicin cream + metformin group. After 4 weeks of continuous drug administration, the blood glucose, body weight, behavioral indexes, and sciatic nerve conduction velocity were measured. The pathological structure of the DRG and the sciatic nerve were observed. PLC- β 3 mRNA and protein levels in the DRG of rats were measured. Compared with the model group, the high-dose WTHX-Cream group showed increased sciatic nerve conduction velocity, improved sciatic nerve morphological changes, and increased expression of PLC- β 3 mRNA and protein in the DRG. This study showed that WTHX-Cream improves hyperalgesia symptoms of DPN by inhibiting the reduction of PLC- β 3 mRNA and protein expression in the diabetic DRG of DPN rats.

Estimation of health-related-quality of life depends on which utility measure is selected for patients with carpal tunnel syndrome.

PubMed

Nazari, Goris; MacDermid, Joy C; Bain, James; Levis, Carolyn M; Thoma, Achilleas

Cross-sectional. Carpal tunnel syndrome (CTS) refers to the compression neuropathy of the median nerve at the wrist. To establish the interinstrument reliability, convergent construct validity, and the levels of agreement of health utility indexes 2 and 3 (HUI-2 and HUI-3), EuroQol 5-dimensions (EQ-5D), EuroQol-visual analog scale (EQ-VAS) and to determine the difference of these utility measures based on age and gender in patients with carpal tunnel syndrome. Seventy-four patients with a confirmed diagnosis of carpal tunnel syndrome completed the 3 questionnaires and EQ-VAS a month before surgery. Demographic characteristics were reported. Intraclass correlation coefficients were used to assess relative interinstrument reliability. Pearson correlation coefficients (r) were used to establish convergent construct validity. Bland-Altman plots and t tests were used to describe the levels of agreement between the 4 utility measures. A 2-way analysis of variance was performed to determine the effect of age and gender on the utility measures; HUI-2, HUI-3, and EQ-5D. The intraclass correlation coefficients were 0.85 for HUI-3 vs HUI-2 and 0.80 for HUI-2 vs EQ-VAS. Pearson correlation coefficients ranged from 0.60 to 0.89; HUI-3 vs HUI-2: 0.89, and HUI-3 vs EQ-5D: 0.60. One-sample t test demonstrated significant differences between HUI-3 vs HUI-2, HUI-3 vs EQ-5D, and HUI-3 vs EQ-VAS measures, with mean differences of -0.12, -0.15, and -0.14, respectively. A 2-way analysis of variance test controlling for age and gender indicated neither as predictors of outcome scores. The HUI-3 vs HUI-2 and HUI-2 vs EQ-VAS demonstrated excellent interinstrument relative reliability measures. The HUI-3 vs HUI-2 displayed very strong convergent construct validity measures, and strong validity measures were established between the remaining utility measures. In addition, the pair-wise utility comparisons demonstrated minimal bias between HUI-2 vs EQ-5D, HUI-2 vs EQ-VAS, and EQ-VAS vs EQ

Combination of counterpropagation artificial neural networks and antioxidant activities for comprehensive evaluation of associated-extraction efficiency of various cyclodextrins in the traditional Chinese formula Xue-Zhi-Ning.

PubMed

Sun, Lili; Yang, Jianwen; Wang, Meng; Zhang, Huijie; Liu, Yanan; Ren, Xiaoliang; Qi, Aidi

2015-11-10

Xue-Zhi-Ning (XZN) is a widely used traditional Chinese medicine formula to treat hyperlipidemia. Recently, cyclodextrins (CDs) have been extensively used to minimize problems relative to medicine bioavailability, such as low solubility and poor stability. The objective of this study was to determine the associated-extraction efficiency of various CDs in XZN. Three various type CDs were evaluated, including native CDs (α-CD, β-CD), hydrophilic CD derivatives (HP-β-CD and Me-β-CD), and ionic CD derivatives (SBE-β-CD and CM-β-CD). An ultra high-performance liquid chromatography (UHPLC) fingerprint was applied to determine the components in CD extracts and original aqueous extract (OAE). A counterpropagation artificial neural network (CP-ANN) was used to analyze the components in different extracts and compare the selective extraction of various CDs. Extraction efficiencies of the various CDs in terms of extracted components follow the ranking, ionic CD derivatives>hydrophilic CD derivatives>native CDs>OAE. Besides, different types of CDs have their own selective extraction and ionic CD derivatives present the strongest associated-extraction efficiency. Antioxidant potentials of various extracts were evaluated by determining the inhibition of spontaneous, H2O2-induced, CCl4-induced and Fe(2+)/ascorbic acid-induced lipid peroxidation (LPO) and analyzing the scavenging capacity for DPPH and hydroxyl radicals. The order of extraction efficiencies of the various CDs relative to antioxidant activities is as follows: SBE-β-CD>CM-β-CD>HP-β-CD>Me-β-CD>β-CD>α-CD. It can be demonstrated that all of the CDs studied increase the extraction efficiency and that ionic CD derivatives (SBE-β-CD and CM-β-CD) present the highest extraction capability in terms of amount extracted and antioxidant activities of extracts. Copyright © 2015 Elsevier B.V. All rights reserved.

Scale-Dependent Infrared Radiative Damping Rates on Mars and Their Role in the Deposition of Gravity-Wave Momentum Flux

DTIC Science & Technology

2010-01-01

1984; Zhu and Strobel , 1991; Zhu, 1993; Bresser et al., 1995) and the resulting scale-dependent IR damping rates have been incorporated within...determining total non-LTE cooling rates over the entire band. Offline calculations by Zhu and Strobel (1990) found errors of no more than ∼1 K day−1 in...and Strobel (1991) and Zhu (1993), who provide more details and justification. If we add small temperature perturbations δT to a background

Organo-Soluble Porphyrin Mixed Monolayer-Protected Gold Nanorods with Intercalated Fullerenes

DTIC Science & Technology

2012-03-16

Mixed Monolayer- Protected Gold Nanorods with Intercalated Fullerenes Chenming Xue, Yongqian Xu, Yi Pang, Dingshan Yu, Liming Dai, Min Gao, Augustine...Protected Gold Nanorods with Intercalated Fullerenes 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT... Fullerenes Chenming Xue, † Yongqian Xu, ‡ Yi Pang, ‡ Dingshan Yu, § Liming Dai, § Min Gao, † Augustine Urbas ± and Quan

Hui Wei | NREL

Science.gov Websites

, bioinformatics, and literature analyses. In total, 75 proteins were identified using the in-solution method, and 236 proteins were identified using the in-gel method, among which approximately 10% of proteins were Molecular Biology (2012) "Tracking Dynamics of Biomass Composting by Monitoring the Changes in

A review of preference-based measures for the assessment of quality of life in children and adolescents with cerebral palsy.

PubMed

Mpundu-Kaambwa, Christine; Chen, Gang; Huynh, Elisabeth; Russo, Remo; Ratcliffe, Julie

2018-07-01

To examine the psychometric properties and suitability for use within the context of cerebral palsy research in children and adolescents of generic preference-based outcome measures (PROMs). Nine electronic databases were searched in this systematic review. The consensus-based standards for the selection of health measurement instruments (COSMIN) checklist were used to measure the psychometric properties of the PROMs. A meta-analysis was used to pool correlation coefficients for convergent validity using the Schmidt-Hunter method. Heterogeneity was assessed using the I-squared statistic (I 2 ). Four preference-based PROMs were identified from eight studies: Health Utilities Index-Mark 2 and 3 (HUI-2 and HUI-3, respectively), the Assessment Quality of Life-4 dimension (AQoL-4D) and the EuroQol-5 dimension 3 level (EQ-5D-3L). Only the HUI system was primarily developed for application with children/adolescents though health-state values for scoring the PROM were elicited from adults. The HUI-3 covered the most relevant constructs though it excludes important modules of health-related quality of life (HRQOL) such as activity limitations and participation restrictions. In terms of psychometric properties, evidence was presented for only five of COSMIN measurement properties: reliability (HUI3), measurement error (HUI-3), content validity (HUI-2 and HUI-3), Hypotheses testing (HUI-3 and AQoL-4D) and criterion validity (HUI-3). No papers reported on internal consistency, structural validity, cross-cultural validity or responsiveness of the preference-based measures in children and adolescents with cerebral palsy. This review highlights the dearth in studies using preference-based PROMs to measure HRQOL associated with cerebral palsy in children and adolescents. The HUI-3 demonstrated the strongest psychometric properties, though it does not cover all dimensions relevant to this population.

An advanced temporal credential-based security scheme with mutual authentication and key agreement for wireless sensor networks.

PubMed

Li, Chun-Ta; Weng, Chi-Yao; Lee, Cheng-Chi

2013-07-24

Wireless sensor networks (WSNs) can be quickly and randomly deployed in any harsh and unattended environment and only authorized users are allowed to access reliable sensor nodes in WSNs with the aid of gateways (GWNs). Secure authentication models among the users, the sensor nodes and GWN are important research issues for ensuring communication security and data privacy in WSNs. In 2013, Xue et al. proposed a temporal-credential-based mutual authentication and key agreement scheme for WSNs. However, in this paper, we point out that Xue et al.'s scheme cannot resist stolen-verifier, insider, off-line password guessing, smart card lost problem and many logged-in users' attacks and these security weaknesses make the scheme inapplicable to practical WSN applications. To tackle these problems, we suggest a simple countermeasure to prevent proposed attacks while the other merits of Xue et al.'s authentication scheme are left unchanged.

An Advanced Temporal Credential-Based Security Scheme with Mutual Authentication and Key Agreement for Wireless Sensor Networks

PubMed Central

Li, Chun-Ta; Weng, Chi-Yao; Lee, Cheng-Chi

2013-01-01

Wireless sensor networks (WSNs) can be quickly and randomly deployed in any harsh and unattended environment and only authorized users are allowed to access reliable sensor nodes in WSNs with the aid of gateways (GWNs). Secure authentication models among the users, the sensor nodes and GWN are important research issues for ensuring communication security and data privacy in WSNs. In 2013, Xue et al. proposed a temporal-credential-based mutual authentication and key agreement scheme for WSNs. However, in this paper, we point out that Xue et al.'s scheme cannot resist stolen-verifier, insider, off-line password guessing, smart card lost problem and many logged-in users' attacks and these security weaknesses make the scheme inapplicable to practical WSN applications. To tackle these problems, we suggest a simple countermeasure to prevent proposed attacks while the other merits of Xue et al.'s authentication scheme are left unchanged. PMID:23887085

Design of Experiment Approach to Hydrogen Re-embrittlement Evaluation WP-2152

DTIC Science & Technology

2015-04-01

2152 by Scott M Grendahl, Hoang Nguyen, Franklin Kellogg , Shuying Zhu, and Stephen Jones Approved for public release...and Materials Research Directorate, ARL Hoang Nguyen and Franklin Kellogg Bowhead Science and Technology, LLC Shuying Zhu and Stephen Jones The...ELEMENT NUMBER 6. AUTHOR(S) Scott M Grendahl, Hoang Nguyen, Franklin Kellogg , Shuying Zhu, and Stephen Jones 5d. PROJECT NUMBER W74RDV20769717 5e

YangXue QingNao Wan and Silibinin Capsules, the Two Chinese Medicines, Attenuate Cognitive Impairment in Aged LDLR (+/-) Golden Syrian Hamsters Involving Protection of Blood Brain Barrier

PubMed Central

Gu, You-Yu; Huang, Ping; Li, Quan; Liu, Yu-Ying; Liu, George; Wang, Yu-Hui; Yi, Ming; Yan, Li; Wei, Xiao-Hong; Yang, Lei; Hu, Bai-He; Zhao, Xin-Rong; Chang, Xin; Sun, Kai; Pan, Chun-Shui; Cui, Yuan-Chen; Chen, Qing-Fang; Wang, Chuan-She; Fan, Jing-Yu; Ma, Zhi-Zhong; Han, Jing-Yan

2018-01-01

The purpose of the study was to explore the effect and the underlying mechanism of YangXue QingNao Wan (YXQNW) and Silibinin Capsules (SC), the two Chinese medicines, on cognitive impairment in older people with familial hyperlipidaemia. Fourteen month-old female LDLR (+/-) golden Syrian hamsters were used with their wild type as control. YXQNW (0.5 g/kg/day), SC (0.1 g/kg/day), or YXQNW (0.5 g/kg/day) + SC (0.1 g/kg/day) were administrated orally for 30 days. To assess the effects of the two drugs on plasma lipid content and cognitive ability, plasma TC, TG, LDL-C, and HDL-C were measured, and Y maze task was carried out both before and after administration. After administering of the drugs for 30 days, to evaluate the effect of the two drugs on disturbed blood flow caused by hyperlipidemia, the cerebral blood flow (CBF) was measured. To assess blood–brain barrier integrity, albumin leakage in middle cerebral artery (MCA) area was determined. To evaluate the effect of the drugs on impaired microvessels, the number and morphology of microvessels were assessed in hippocampus area. To further evaluate the ultrastructure of microvessels in hippocampus, transmission electron microscopy (TEM) and scanning electron microscopy (SEM) were carried out. To assess the profiles of claudin-5 and occludin in hippocampus, we performed immunofluorescence. Finally, to assess the expression of claudin-5, JAM-1, occludin and ZO-1 in hippocampus, western blot was carried out. The results showed that YXQNW, SC, and YXQNW + SC improved cognitive impairment of aged LDLR (+/-) golden Syrian hamsters without lowering plasma TC and LDL-C. YXQNW, SC, and YXQNW + SC attenuated albumin leakage in MCA area and neuronal damage in hippocampus, concomitant with an increase in CBF, a decrease of perivascular edema and an up-regulated expression of claudin-5, occludin and ZO-1. In conclusion, YXQNW, SC, and YXQNW + SC are able to improve cognitive ability in aged LDLR (+/-) golden Syrian hamsters

The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study.

PubMed

Papaioannou, A; Kennedy, C C; Ioannidis, G; Sawka, A; Hopman, W M; Pickard, L; Brown, J P; Josse, R G; Kaiser, S; Anastassiades, T; Goltzman, D; Papadimitropoulos, M; Tenenhouse, A; Prior, J C; Olszynski, W P; Adachi, J D

2009-05-01

Using prospective data from the Canadian Multicentre Osteoporosis Study (CaMos), we compared health utilities index (HUI) scores after 5 years of follow-up among participants (50 years and older) with and without incident clinical fractures. Incident fractures had a negative impact on HUI scores over time. This study examined change in health-related quality of life (HRQL) in those with and without incident clinical fractures as measured by the HUI. The study cohort was 4,820 women and 1,783 men (50 years and older) from the CaMos. The HUI was administered at baseline and year 5. Participants were sub-divided into incident fracture groups (hip, rib, spine, forearm, pelvis, other) and were compared with those without these fractures. The effects of both time and fracture type on HUI scores were examined in multivariable regression analyses. Men and women with hip fractures, compared to those without, had lower HUI measures that ranged from -0.05 to -0.25. Both women and men with spine fractures had significant deficits on the pain attributes (-0.07 to -0.12). In women, self-care (-0.06), mobility and ambulation (-0.05) were also negatively impacted. Women with rib fractures had deficits similar to women with spine fractures, and these effects persisted over time. In men, rib fractures did not significantly affect HUI scores. Pelvic and forearm fractures did not substantially influence HUI scores. The HUI was a sensitive measure of HRQL change over time. These results will inform economic analyses evaluating osteoporosis therapies.

Study on spatial-temporal change of Changsha-Zhuzhou-Xiangtan urban agglomeration based on DMSP / OLS night light data

NASA Astrophysics Data System (ADS)

Li, Mao; Li, Lel-in

2018-03-01

For the sake of curbing the spreading of Changsha-Zhuzhou-Xiangtan urban agglomeration and spatial disorder in the process of urbanization development on the regional bearing capacity of land resources and ecological environment and assisting to plan the integration process of ChangZhuTan,this paper uses the DMSP/OLS night light data of Chang ZhuTan in 1992 to 2013 to invert the urbanization process index of ChangZhuTan urban agglomeration. Based on the two scales of time and space, this paper analyzes the average index of lights, the speed of urban expansion and urban compactness index et al and studies the temporal and spatial characteristics of ChangZhuTan urban agglomeration in this period.

A Computing Platform for Parallel Sparse Matrix Computations

DTIC Science & Technology

2016-01-05

REPORT NUMBER 19a. NAME OF RESPONSIBLE PERSON 19b. TELEPHONE NUMBER Ahmed Sameh Ahmed H. Sameh, Alicia Klinvex, Yao Zhu 611103 c. THIS PAGE The...PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Discipline Yao Zhu 0.50 Alicia Klinvex 0.10 0.60 2 Names of Post Doctorates Names of Faculty Supported...PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: NAME Total Number: NAME Total Number: Yao Zhu Alicia Klinvex 2 ...... ...... Sub Contractors (DD882) Names of other

p38 MAPK signal pathway involved in anti-inflammatory effect of Chaihu-Shugan-San and Shen-ling-bai-zhu-San on hepatocyte in non-alcoholic steatohepatitis rats.

PubMed

Yang, QinHe; Xu, YongJian; Feng, GaoFei; Hu, ChaoFeng; Zhang, YuPei; Cheng, ShaoBing; Wang, YanPing; Gong, XiangWen

2014-01-01

Traditional Chinese Medicine (TCM), has over thousands-of-years history of use. Chaihu-Shugan-San (CSS), and Shen-ling-bai-zhu-San (SLBZS), are famous traditional Chinese herbal medicine formulas, which have been used in China, for the treatment of many chronic diseases. This study investigated the anti-inflammatory effects of CSS and SLBZS on signaling molecules involved in p38 mitogen-activated protein kinase (p38 MAPK), pathway on hepatocytes of non-alcoholic steatohepatitis (NASH), rats induced by high fat diet. SD male rats were randomly divided into 8 groups: negative control group, model control group, high (9.6g/kg/day)/low (3.2g/kg/day)-dose CSS group, high (30g/kg/day)/low (10g/kg/day)-dose SLBZS group, high (39.6g/kg/day)/low (13.2g/kg/day)-dose integrated group. The rats of NASH model were induced by feeding a high-fat diet. After 16, wks, Hepatocytes were isolated from 6, rats in each group by collagenase perfusion. The liver histopathological changes and serum inflammatory cytokines TNF-α, IL-6 were determined. The proteins of TLR4, phosphor-p38 MAPK and p38 MAPK involved in p38 MAPK signal pathway were assayed. The statistical data indicated the NASH model rats reproduced typical histopathological features of NASH in human. CSS and SLBZS ameliorated lipid metabolic disturbance, attenuated NASH progression, decreased the levels of TNF-α and IL-6 in serum, as well as inhibited TLR4 protein expression, p38 MAPK phosphorylation, and activation of p38 MAPK. In conclusion, CSS and SLBZS might work as a significant anti-inflammatory effect on hepatocyte of NASH by inhibiting the activation of TLR4, p-p38 MAPK and p38 MAPK involved in p38 MAPK signal pathway. To some extent, CSS and SLBZS may be a potential alternative and complementary medicine to protect against liver injury, alleviate the inflammation reaction, moderate NASH progression.

A parent-child dyad approach to the assessment of health status and health-related quality of life in children with asthma.

PubMed

Ungar, Wendy J; Boydell, Katherine; Dell, Sharon; Feldman, Brian M; Marshall, Deborah; Willan, Andrew; Wright, James G

2012-08-01

Assessment of health state and health-related quality of life (HR-QOL) are limited by a child's age and cognitive ability. Parent-proxy reports are known to differ from children's reports. Simultaneous assessment using a parent-child dyad is an alternative approach. Our objective was to assess the validity, reliability and responsiveness of a parent-child dyad approach to utility and HR-QOL assessment of paediatric asthma health states. The setting was specialist care in a hospital-based asthma clinic. Participants were 91 girls and boys with asthma aged 8 to 17 years and 91 parents. The intervention employed was parent-child dyad administration of the Health Utilities Index (HUI) 2 and 3, the Pediatric Quality of Life Inventory™ (PedsQL™) Core and Asthma modules, and the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). Questionnaires were administered by interview to children and parents separately and then together as a dyad to assess the child's health state. The dyad interview was repeated at the next clinic visit. Dyad-child agreement was measured by intra-class correlation (ICC) coefficient; Spearman correlations were used to assess convergent validity. Test-retest reliability was assessed in 28 children who remained clinically stable between visits with a two-way ICC coefficient. Responsiveness to change from baseline was assessed with Spearman coefficients in 30 children who demonstrated clinical change between visits. There was no significant agreement between parent and child for the HUI2 or HUI3 whereas agreement between dyad and child was 0.55 (95% confidence interval [CI] 0.36, 0.69) for the HUI2 and 0.74 (95% CI 0.61, 0.82) for the HUI3 overall. With respect to dyad performance characteristics, both HUI2 and HUI3 overall scores demonstrated moderate convergent validity with the generic PedsQL™ Core domains (range r = 0.30-0.52; p < 0.01). Dyad HUI2 attributes demonstrated moderate convergent validity with the generic Peds

A Parent-Child Dyad Approach to the Assessment of Health Status and Health-Related Quality of Life in Children with Asthma

PubMed Central

Ungar, Wendy J.; Boydell, Katherine; Dell, Sharon; Feldman, Brian M.; Marshall, Deborah; Willan, Andrew; Wright, James G.

2016-01-01

Background Assessment of health state and health-related quality of life (HR-QOL) are limited by a child’s age and cognitive ability. Parent-proxy reports are known to differ from children’s reports. Simultaneous assessment using a parent-child dyad is an alternative approach. Objective Our objective was to assess the validity, reliability and responsiveness of a parent-child dyad approach to utility and HR-QOL assessment of paediatric asthma health states. Methods The setting was specialist care in a hospital-based asthma clinic. Participants were 91 girls and boys with asthma aged 8 to 17 years and 91 parents. The intervention employed was parent-child dyad administration of the Health Utilities Index (HUI) 2 and 3, the Pediatric Quality of Life Inventory™ (PedsQL™) Core and Asthma modules, and the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). Questionnaires were administered by interview to children and parents separately and then together as a dyad to assess the child’s health state. The dyad interview was repeated at the next clinic visit. Dyad-child agreement was measured by intra-class correlation (ICC) coefficient; Spearman correlations were used to assess convergent validity. Test-retest reliability was assessed in 28 children who remained clinically stable between visits with a two-way ICC coefficient. Responsiveness to change from baseline was assessed with Spearman coefficients in 30 children who demonstrated clinical change between visits. Results There was no significant agreement between parent and child for the HUI2 or HUI3 whereas agreement between dyad and child was 0.55 (95% confidence interval [CI] 0.36, 0.69) for the HUI2 and 0.74 (95% CI 0.61, 0.82) for the HUI3 overall. With respect to dyad performance characteristics, both HUI2 and HUI3 overall scores demonstrated moderate convergent validity with the generic PedsQL™ Core domains (range r = 0.30–0.52; p < 0.01). Dyad HUI2 attributes demonstrated moderate convergent

Cadmium accumulation characteristics of low-cadmium rice (Oryza sativa L.) line and F1 hybrids grown in cadmium-contaminated soils.

PubMed

Li, Kun; Yu, Haiying; Li, Tingxuan; Chen, Guangdeng; Huang, Fu

2017-07-01

Cadmium (Cd) pollution has threatened severely to food safety and human health. A pot experiment and a field experiment were conducted to investigate the difference of Cd accumulation between rice (Oryza sativa L.) lines and F 1 hybrids in Cd-contaminated soils. The adverse effect on biomass of rice lines was greater than that of F 1 hybrids under Cd treatments in the pot experiment. The variations of Cd concentration among rice cultivars in different organs were smaller in stem and leaf, but larger in root and ear. Average proportion of Cd in root of F 1 hybrids was 1.39, 1.39, and 1.16 times higher than those of rice lines at the treatment of 1, 2, and 4 mg Cd kg -1 soil, respectively. Cd concentrations in ear of F 1 hybrids were significantly lower than rice lines with the reduction from 29.24 to 50.59%. Cd concentrations in brown rice of all F 1 hybrids were less than 0.2 mg kg -1 at 1 mg Cd kg -1 soil, in which Lu98A/YaHui2816, 5406A/YaHui2816, and C268A/YaHui2816 could be screened out as cadmium-safe cultivars (CSCs) for being safe even at 2 mg Cd kg -1 soil. C268A/YaHui2816 showed the lowest Cd concentration in root among F 1 hybrids, while Lu98A/YaHui2816 and 5406A/YaHui2816 showed lower capability of Cd translocation from root to shoot under Cd exposure, which eventually caused the lower Cd accumulation in brown rice. The lower level of Cd translocation contributed to reducing the accumulation of Cd in brown rice had been validated by the field experiment. Thus, Lu98A/YaHui2816, 5406A/YaHui2816, and C268A/YaHui2816 could be considered as potential CSCs to cultivate in Cd-contaminated soils (<2 mg Cd kg -1 soil).

Health state utility instruments compared: inquiring into nonlinearity across EQ-5D-5L, SF-6D, HUI-3 and 15D.

PubMed

Gamst-Klaussen, Thor; Chen, Gang; Lamu, Admassu N; Olsen, Jan Abel

2016-07-01

Different health state utility (HSU) instruments produce different utilities for the same individuals, thereby compromising the intended comparability of economic evaluations of health care interventions. When developing crosswalks, previous studies have indicated nonlinear relationships. This paper inquires into the degree of nonlinearity across the four most widely used HSU-instruments and proposes exchange rates that differ depending on the severity levels of the health state utility scale. Overall, 7933 respondents from six countries, 1760 in a non-diagnosed healthy group and 6173 in seven disease groups, reported their health states using four different instruments: EQ-5D-5L, SF-6D, HUI-3 and 15D. Quantile regressions investigate the degree of nonlinear relationships between these instruments. To compare the instruments across different disease severities, we split the health state utility scale into utility intervals with 0.2 successive decrements in utility starting from perfect health at 1.00. Exchange rates (ERs) are calculated as the mean utility difference between two utility intervals on one HSU-instrument divided by the difference in mean utility on another HSU-instrument. Quantile regressions reveal significant nonlinear relationships across all four HSU-instruments. The degrees of nonlinearities differ, with a maximum degree of difference in the coefficients along the health state utility scale of 3.34 when SF-6D is regressed on EQ-5D. At the lower end of the health state utility scale, the exchange rate from SF-6D to EQ-5D is 2.11, whilst at the upper end it is 0.38. Comparisons at different utility levels illustrate the fallacy of using linear functions as crosswalks between HSU-instruments. The existence of nonlinear relationships between different HSU-instruments suggests that level-specific exchange rates should be used when converting a change in utility on the instrument used, onto a corresponding utility change had another instrument been

Standard error of measurement of 5 health utility indexes across the range of health for use in estimating reliability and responsiveness.

PubMed

Palta, Mari; Chen, Han-Yang; Kaplan, Robert M; Feeny, David; Cherepanov, Dasha; Fryback, Dennis G

2011-01-01

Standard errors of measurement (SEMs) of health-related quality of life (HRQoL) indexes are not well characterized. SEM is needed to estimate responsiveness statistics, and is a component of reliability. To estimate the SEM of 5 HRQoL indexes. The National Health Measurement Study (NHMS) was a population-based survey. The Clinical Outcomes and Measurement of Health Study (COMHS) provided repeated measures. A total of 3844 randomly selected adults from the noninstitutionalized population aged 35 to 89 y in the contiguous United States and 265 cataract patients. The SF6-36v2™, QWB-SA, EQ-5D, HUI2, and HUI3 were included. An item-response theory approach captured joint variation in indexes into a composite construct of health (theta). The authors estimated 1) the test-retest standard deviation (SEM-TR) from COMHS, 2) the structural standard deviation (SEM-S) around theta from NHMS, and 3) reliability coefficients. SEM-TR was 0.068 (SF-6D), 0.087 (QWB-SA), 0.093 (EQ-5D), 0.100 (HUI2), and 0.134 (HUI3), whereas SEM-S was 0.071, 0.094, 0.084, 0.074, and 0.117, respectively. These yield reliability coefficients 0.66 (COMHS) and 0.71 (NHMS) for SF-6D, 0.59 and 0.64 for QWB-SA, 0.61 and 0.70 for EQ-5D, 0.64 and 0.80 for HUI2, and 0.75 and 0.77 for HUI3, respectively. The SEM varied across levels of health, especially for HUI2, HUI3, and EQ-5D, and was influenced by ceiling effects. Limitations. Repeated measures were 5 mo apart, and estimated theta contained measurement error. The 2 types of SEM are similar and substantial for all the indexes and vary across health.

Potential of Silanes for Chromate Replacement in Metal Finishing Industries

DTIC Science & Technology

2002-09-16

POTENTIAL OF SILANES FOR CHROMATE REPLACEMENT IN METAL FINISHING INDUSTRIES Wim J. van Ooij*, Danqing Zhu, Vignesh Palanivel, J. Anna Lamar...18 2 POTENTIAL OF SILANES FOR CHROMATE REPLACEMENT IN METAL FINISHING INDUSTRIES Wim J. van Ooij, Danqing Zhu, Vignesh Palanivel, J. Anna Lamar

Preventing Terror Attacks in the Homeland: A New Mission for State and Local Police

DTIC Science & Technology

2005-09-01

18 Dale Couprie, Alan Goodbrand, Bin Li, and David Zhu, “ Soft Systems Methodology ,” Department of Computer Science (University of Calgary, 2002...Activities Authorization Act.” (50 USC. 403-1). June 2005. Couprie, Dale, Alan Goodbrand, Bin Li, and David Zhu. “ Soft Systems Methodology .” Department

Immunosuppressive Mesenchymal Stromal Cells Derived from Human-Induced Pluripotent Stem Cells Induce Human Regulatory T Cells In Vitro and In Vivo

PubMed Central

Roux, Clémence; Saviane, Gaëlle; Pini, Jonathan; Belaïd, Nourhène; Dhib, Gihen; Voha, Christine; Ibáñez, Lidia; Boutin, Antoine; Mazure, Nathalie M.; Wakkach, Abdelilah; Blin-Wakkach, Claudine; Rouleau, Matthieu

2018-01-01

Despite mesenchymal stromal cells (MSCs) are considered as a promising source of cells to modulate immune functions on cells from innate and adaptive immune systems, their clinical use remains restricted (few number, limited in vitro expansion, absence of a full phenotypic characterization, few insights on their in vivo fate). Standardized MSCs derived in vitro from human-induced pluripotent stem (huIPS) cells, remediating part of these issues, are considered as well as a valuable tool for therapeutic approaches, but their functions remained to be fully characterized. We generated multipotent MSCs derived from huiPS cells (huiPS-MSCs), and focusing on their immunosuppressive activity, we showed that human T-cell activation in coculture with huiPS-MSCs was significantly reduced. We also observed the generation of functional CD4+ FoxP3+ regulatory T (Treg) cells. Further tested in vivo in a model of human T-cell expansion in immune-deficient NSG mice, huiPS-MSCs immunosuppressive activity prevented the circulation and the accumulation of activated human T cells. Intracytoplasmic labeling of cytokines produced by the recovered T cells showed reduced percentages of human-differentiated T cells producing Th1 inflammatory cytokines. By contrast, T cells producing IL-10 and FoxP3+-Treg cells, absent in non-treated animals, were detected in huiPS-MSCs treated mice. For the first time, these results highlight the immunosuppressive activity of the huiPS-MSCs on human T-cell stimulation with a concomitant generation of human Treg cells in vivo. They may favor the development of new tools and strategies based on the use of huiPS cells and their derivatives for the induction of immune tolerance. PMID:29422893

Immunosuppressive Mesenchymal Stromal Cells Derived from Human-Induced Pluripotent Stem Cells Induce Human Regulatory T Cells In Vitro and In Vivo.

PubMed

Roux, Clémence; Saviane, Gaëlle; Pini, Jonathan; Belaïd, Nourhène; Dhib, Gihen; Voha, Christine; Ibáñez, Lidia; Boutin, Antoine; Mazure, Nathalie M; Wakkach, Abdelilah; Blin-Wakkach, Claudine; Rouleau, Matthieu

2017-01-01

Despite mesenchymal stromal cells (MSCs) are considered as a promising source of cells to modulate immune functions on cells from innate and adaptive immune systems, their clinical use remains restricted (few number, limited in vitro expansion, absence of a full phenotypic characterization, few insights on their in vivo fate). Standardized MSCs derived in vitro from human-induced pluripotent stem (huIPS) cells, remediating part of these issues, are considered as well as a valuable tool for therapeutic approaches, but their functions remained to be fully characterized. We generated multipotent MSCs derived from huiPS cells (huiPS-MSCs), and focusing on their immunosuppressive activity, we showed that human T-cell activation in coculture with huiPS-MSCs was significantly reduced. We also observed the generation of functional CD4 + FoxP3 + regulatory T (Treg) cells. Further tested in vivo in a model of human T-cell expansion in immune-deficient NSG mice, huiPS-MSCs immunosuppressive activity prevented the circulation and the accumulation of activated human T cells. Intracytoplasmic labeling of cytokines produced by the recovered T cells showed reduced percentages of human-differentiated T cells producing Th1 inflammatory cytokines. By contrast, T cells producing IL-10 and FoxP3 + -Treg cells, absent in non-treated animals, were detected in huiPS-MSCs treated mice. For the first time, these results highlight the immunosuppressive activity of the huiPS-MSCs on human T-cell stimulation with a concomitant generation of human Treg cells in vivo . They may favor the development of new tools and strategies based on the use of huiPS cells and their derivatives for the induction of immune tolerance.

National Libraries Section. General Research Libraries Division. Papers.

ERIC Educational Resources Information Center

International Federation of Library Associations, The Hague (Netherlands).

Papers on national library services and activities, which were presented at the 1983 International Federation of Library Associations (IFLA) conference, include: (1) "The National Library of China in its Gradual Application of Modern Technology," a discussion by Zhu Nan and Zhu Yan (China) of microform usage and library automation; (2)…

WAIS-IV and WISC-IV Structural Validity: Alternate Methods, Alternate Results. Commentary on Weiss et al. (2013a) and Weiss et al. (2013b)

ERIC Educational Resources Information Center

Canivez, Gary L.; Kush, Joseph C.

2013-01-01

Weiss, Keith, Zhu, and Chen (2013a) and Weiss, Keith, Zhu, and Chen (2013b), this issue, report examinations of the factor structure of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) and Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV), respectively; comparing Wechsler Hierarchical Model (W-HM) and…

Standard error of measurement of five health utility indexes across the range of health for use in estimating reliability and responsiveness

PubMed Central

Palta, Mari; Chen, Han-Yang; Kaplan, Robert M.; Feeny, David; Cherepanov, Dasha; Fryback, Dennis

2011-01-01

Background Standard errors of measurement (SEMs) of health related quality of life (HRQoL) indexes are not well characterized. SEM is needed to estimate responsiveness statistics and provides guidance on using indexes on the individual and group level. SEM is also a component of reliability. Purpose To estimate SEM of five HRQoL indexes. Design The National Health Measurement Study (NHMS) was a population based telephone survey. The Clinical Outcomes and Measurement of Health Study (COMHS) provided repeated measures 1 and 6 months post cataract surgery. Subjects 3844 randomly selected adults from the non-institutionalized population 35 to 89 years old in the contiguous United States and 265 cataract patients. Measurements The SF6-36v2™, QWB-SA, EQ-5D, HUI2 and HUI3 were included. An item-response theory (IRT) approach captured joint variation in indexes into a composite construct of health (theta). We estimated: (1) the test-retest standard deviation (SEM-TR) from COMHS, (2) the structural standard deviation (SEM-S) around the composite construct from NHMS and (3) corresponding reliability coefficients. Results SEM-TR was 0.068 (SF-6D), 0.087 (QWB-SA), 0.093 (EQ-5D), 0.100 (HUI2) and 0.134 (HUI3), while SEM-S was 0.071, 0.094, 0.084, 0.074 and 0.117, respectively. These translate into reliability coefficients for SF-6D: 0.66 (COMHS) and 0.71 (NHMS), for QWB: 0.59 and 0.64, for EQ-5D: 0.61 and 0.70 for HUI2: 0.64 and 0.80, and for HUI3: 0.75 and 0.77, respectively. The SEM varied considerably across levels of health, especially for HUI2, HUI3 and EQ-5D, and was strongly influenced by ceiling effects. Limitations Repeated measures were five months apart and estimated theta contain measurement error. Conclusions The two types of SEM are similar and substantial for all the indexes, and vary across the range of health. PMID:20935280

Demographic and Prescribing Patterns of Chinese Herbal Products for Individualized Therapy for Ischemic Heart Disease in Taiwan: Population-Based Study

PubMed Central

Hu, Wen-Long; Chen, Hsuan-Ju; Li, Tsai-Chung; Tsai, Pei-Yuan; Chen, Hsin-Ping; Huang, Meng-Hsuan; Su, Fang-Yen

2015-01-01

Objective Combinations of Chinese herbal products (CHPs) are widely used for ischemic heart disease (IHD) in Taiwan. We analyzed the usage and frequency of CHPs prescribed for patients with IHD. Methods A nationwide population-based cross-sectional study was conducted, 53531 patients from a random sample of one million in the National Health Insurance Research Database (NHIRD) from 2000 to 2010 were enrolled. Descriptive statistics, the multiple logistic regression method and Poisson regression analysis were employed to estimate the adjusted odds ratios (aORs) and adjusted risk ratios (aRRs) for utilization of CHPs. Results The mean age of traditional Chinese medicine (TCM) nonusers was significantly higher than that of TCM users. Zhi-Gan-Cao-Tang (24.85%) was the most commonly prescribed formula CHPs, followed by Xue-Fu-Zhu-Yu-Tang (16.53%) and Sheng-Mai-San (16.00%). The most commonly prescribed single CHPs were Dan Shen (29.30%), Yu Jin (7.44%), and Ge Gen (6.03%). After multivariate adjustment, patients with IHD younger than 29 years had 2.62 times higher odds to use TCM than those 60 years or older. Residents living in Central Taiwan, having hyperlipidemia or cardiac dysrhythmias also have higher odds to use TCM. On the contrary, those who were males, who had diabetes mellitus (DM), hypertension, stroke, myocardial infarction (MI) were less likely to use TCM. Conclusions Zhi-Gan-Cao-Tang and Dan Shen are the most commonly prescribed CHPs for IHD in Taiwan. Our results should be taken into account by physicians when devising individualized therapy for IHD. Further large-scale, randomized clinical trials are warranted in order to determine the effectiveness and safety of these herbal medicines. PMID:26322893

[Variation characteristics of fine particulate matter PM2.5 concentration in three urban recreational forests in Hui Mountain of Wuxi City, Jiangsu Province of East China].

PubMed

Gu, Lin; Wang, Cheng; Wang, Xiao-Lei; Wang, Yan-Ying; Wang, Qian

2013-09-01

It is of significance to understand the controlling effects of urban forest on atmospheric fine particulate matter PM2.5 pollution. This paper monitored the variations of atmospheric PM2.5 concentrations in three typical urban recreational forests (Cinnamomum camphora, Pinus elliotii, and Quercus variabilis ) in the Hui Mountain of Wuxi City during the day time (5:00 am-19:00 pm) in autumn and winter, 2011 and in spring and summer, 2012. The meteorological factors were observed simultaneously. The average annual PM2.5 concentration in the three recreational forests was lower than that above the nearby roads, and this concentration in C. camphora and P. elliotii forests was lower than that in Q. variabilis forest. The average annual PM2.5 concentration in the forests and above the nearby roads was lower than the background value in the downtown area of the City. The PM2.5 concentration in the three recreational forests was the lowest in summer, followed by in autumn, and the highest in spring. In addition, the PM2.5 concentration was the lowest in P. elliotii forest in spring, summer, and winter, and in C. camphora forest in autumn, but relatively higher in Q. variabilis forest in all seasons. The diurnal variation of the PM2.5 concentration in the three forests in four seasons all showed nearly "one peak and one vale", with the peak and vale appeared at 7:00-9:00 and 15:00-19:00, respectively. The PM2.5 concentration was significantly correlated with the air moisture and temperature in four seasons, and significantly correlated with the light intensity in winter. Mild winds throughout the seasons had little effects on the PM2.5 concentration.

Discovering, Understanding and Predicting Emergent Phenomena at Strongly Correlated Oxide Interfaces

DTIC Science & Technology

2013-03-31

Orloff, T. Birol, Y. Zhu, L. Fitting Kourkoutis, V. Goian, R. Haislmaier, E. Vlahos , M.D. Biegalski, N. Benedek, M. Bernhagen, Y. Kim, J.D. Brock, R...invited) C.?H. Lee, N.D. Orloff, T. Birol, Y. Zhu, L. Fitting Kourkoutis, V. Goian, R. Haislmaier, E. Vlahos , M.D. Biegalski, N. Benedek, M. Bernhagen, Y

Improvement in health-related quality of life after lung transplantation

PubMed Central

Santana, Maria-Jose; Feeny, David; Jackson, Katherine; Weinkauf, Justin; Lien, Dale

2009-01-01

BACKGROUND/OBJECTIVE: Traditional survival outcomes do not reflect the effects on the health-related quality of life (HRQL) of patients. HRQL following lung transplantation has not been studied systematically. The Health Utilities Index (HUI) is a family (HUI2 and HUI3) of measures of HRQL that has not been previously used to assess HRQL in lung transplantation. The objective of the present study was to assess the impact of lung transplantation on patient’s HRQL using the HUI. METHODS: A total of 43 patients completed a battery of questionnaires before lung transplantation, and at three months and six months after lung transplantation. The 15-item questionnaire (HUI2 and HUI3) was used. Overall scores were based on a conventional scale (0.00 = dead, 1.00 = perfect health). Mental health was assessed by the Hospital Anxiety and Depression Scale. Adherence to medication and exercise were assessed by Morisky’s and Godin’s questionnaires, respectively. RESULTS: Sixty-five per cent of the patients were men, with a mean age of 53 years (range 18 to 67 years). The mean overall HUI3 score for the lung transplant candidates (0.57) was much lower than for the lung transplant recipients (0.82) at six months post-transplantation. This difference was clinically important and statistically significant (P<0.05 [paired ttest, degrees of freedom (df) = 35]). Differences in mean Hospital Anxiety and Depression Scale scores after transplantation were statistically significant (P<0.05 [paired t test, df=35]). After six months, transplant recipients were more adherent to medication (P<0.05 [χ2 test, df=1]). Recipients were able to increase the duration of exercise at all levels of intensity. CONCLUSION: Lung transplantation improved the patients’ HRQL and adherence to medication. Anxiety levels persisted six months after transplantation but depression levels had decreased significantly. PMID:19851533

NREL Research Pushes Perovskites Closer to Market | News | NREL

Science.gov Websites

cell. Photo by Dennis Schroeder/NREL Kai Zhu, a researcher at the U.S. Department of Energy's National Kai Zhu has been conducting perovskite research at NREL since 2012. Photo by Dennis Schroeder/NREL , creating a solar cell. Photo by Dennis Schroeder/NREL Pioneering Cutting-Edge Research In a solar cell

An authentication scheme for secure access to healthcare services.

PubMed

Khan, Muhammad Khurram; Kumari, Saru

2013-08-01

Last few decades have witnessed boom in the development of information and communication technologies. Health-sector has also been benefitted with this advancement. To ensure secure access to healthcare services some user authentication mechanisms have been proposed. In 2012, Wei et al. proposed a user authentication scheme for telecare medical information system (TMIS). Recently, Zhu pointed out offline password guessing attack on Wei et al.'s scheme and proposed an improved scheme. In this article, we analyze both of these schemes for their effectiveness in TMIS. We show that Wei et al.'s scheme and its improvement proposed by Zhu fail to achieve some important characteristics necessary for secure user authentication. We find that security problems of Wei et al.'s scheme stick with Zhu's scheme; like undetectable online password guessing attack, inefficacy of password change phase, traceability of user's stolen/lost smart card and denial-of-service threat. We also identify that Wei et al.'s scheme lacks forward secrecy and Zhu's scheme lacks session key between user and healthcare server. We therefore propose an authentication scheme for TMIS with forward secrecy which preserves the confidentiality of air messages even if master secret key of healthcare server is compromised. Our scheme retains advantages of Wei et al.'s scheme and Zhu's scheme, and offers additional security. The security analysis and comparison results show the enhanced suitability of our scheme for TMIS.

Polymorphisms of alcohol metabolizing enzymes in indigenous Mexican population: unusual high frequency of CYP2E1*c2 allele.

PubMed

Gordillo-Bastidas, Elizabeth; Panduro, Arturo; Gordillo-Bastidas, Daniela; Zepeda-Carrillo, Eloy A; García-Bañuelos, Jesús J; Muñoz-Valle, José F; Bastidas-Ramírez, Blanca E

2010-01-01

Alcohol abuse represents the major identified etiological factor of cirrhosis in México. ADH1B, ALDH2, and CYP2E1 have been considered candidate genes in alcohol-related diseases. Controversial results probably due to ethnic differences, among other factors, have been reported. Mexican Mestizos (MES) derive from the combination of indigenous, Spaniard, and African genes. Huichols (HUI) constitute an indigenous group from western Mexico with no racial admixture. We determined ADH1B*2, ALDH2*2, and CYP2E1*c2 allele frequencies in healthy HUI and MES from western Mexico. Lipid and hepatic profile were also carried out. One hundred and one HUI and 331 MES subjects were studied. Genotype and allele frequency were assessed through polymerase chain reaction-restriction fragment length polymorphism after DNA isolation from peripheral leukocytes. Commercial kits for lipid and hepatic determinations were used. Polymorphic allele distribution in HUI was: 0%ADH1B*2, 0.5%ALDH2*2, 51.5%CYP2E1*c2; in MES: 3.4%ADH1B*2, 0%ALDH2*2, 16.1%CYP2E1*c2. Frequency of ADH1B*2 was statistically (p < 0.001) lower in HUI than MES. CYP2E1*c2 polymorphic allele was significantly higher (p < 0.0001) in HUI than MES. Hepatic profile was normal in both groups. HUI showed a better lipid profile than MES independently of genotype. Huichols exhibited the highest CYP2E1*c2 allele frequency of the world documented up to this date; meanwhile, ADH1B*2 and ALDH2*2 were practically absent. This feature could be useful in the understanding of Mexican population gene composition, alcohol metabolism, and alcoholic liver disease development. However, further association studies are necessary. The heterogeneity of Mexican population was evidenced by the significantly different distribution of CYP2E1*c2 allele observed among different regions of the country. Lipid and hepatic values were not associated to genotype. This report constitutes the first study dealing with gene polymorphisms of alcohol metabolizing

On the Unsteady-Motion Theory of Magnetic Forces for Maglev

DTIC Science & Technology

1993-11-01

DivisionEnergy Technology Division Forces for Maglev Energy Technology DivisionEnergy Technology Division by S. S. Chen, S. Zhu, and Y. Cai APQ 4 袲...On the Unsteady-Motion Theory of Magnetic Forces for Maglev by S. S. Chen, S. Zhu, and Y. Cai Energy Technology Division November 1993 Work supported...vi On The Unsteady-Motion Theory of Magnetic Forces for Maglev by S. S

Claire Zhu, PhD | Division of Cancer Prevention

Cancer.gov

The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

A secure smart-card based authentication and key agreement scheme for telecare medicine information systems.

PubMed

Lee, Tian-Fu; Liu, Chuan-Ming

2013-06-01

A smart-card based authentication scheme for telecare medicine information systems enables patients, doctors, nurses, health visitors and the medicine information systems to establish a secure communication platform through public networks. Zhu recently presented an improved authentication scheme in order to solve the weakness of the authentication scheme of Wei et al., where the off-line password guessing attacks cannot be resisted. This investigation indicates that the improved scheme of Zhu has some faults such that the authentication scheme cannot execute correctly and is vulnerable to the attack of parallel sessions. Additionally, an enhanced authentication scheme based on the scheme of Zhu is proposed. The enhanced scheme not only avoids the weakness in the original scheme, but also provides users' anonymity and authenticated key agreements for secure data communications.

Faced with Returnees, I Am Very Confident

ERIC Educational Resources Information Center

Song, Xiao; Yan, Long

2004-01-01

This article is an interview with Tu Hui regarding the relative merits of "returnees" and "indigens". Tu Hui is currently chief products inspector at the Anyi Software company and one of the many indigens engaged in Information Technology. In this article, he states that, "the weakness of the indigens sometimes lies in…

Research on the evaluation method of rural hollowing based on RS and GIS technology: a case study of the Ningxia Hui autonomous region in China

NASA Astrophysics Data System (ADS)

Yin, Kai; Wen, MeiPing; Zhang, FeiFei; Yuan, Chao; Chen, Qiang; Zhang, Xiupeng

2016-10-01

With the acceleration of urbanization in China, most rural areas formed a widespread phenomenon, i.e., destitute village, labor population loss, land abandonment and rural hollowing. And it formed a unique hollow village problem in China finally. The governance of hollow village was the objective need of the development of economic and social development in rural area for Chinese government, and the research on the evaluation method of rural hollowing was the premise and basis of the hollow village governance. In this paper, several evaluation methods were used to evaluate the rural hollowing based on the survey data, land use data, social and economic development data. And these evaluation indexes were the transition of homesteads, the development intensity of rural residential areas, the per capita housing construction area, the residential population proportion in rural area, and the average annual electricity consumption, which can reflect the rural hollowing degree from the land, population, and economy point of view, respectively. After that, spatial analysis method of GIS was used to analyze the evaluation result for each index. Based on spatial raster data generated by Kriging interpolation, we carried out re-classification of all the results. Using the fuzzy clustering method, the rural hollowing degree in Ningxia area was reclassified based on the two spatial scales of county and village. The results showed that the rural hollowing pattern in the Ningxia Hui Autonomous Region had a spatial distribution characteristics that the rural hollowing degree was obvious high in the middle of the study area but was low around the study area. On a county scale, the specific performances of the serious rural hollowing were the higher degree of extensive land use, and the lower level of rural economic development and population transfer concentration. On a village scale, the main performances of the rural hollowing were the rural population loss and idle land. The

Nonlinear Wave Propagation

DTIC Science & Technology

2015-05-07

honeycomb lattices, M.J. Ablowitz and Y. Zhu, SIAM J. Appl. Math. 87 (2013) 19591979 11. Nonlinear Temporal-Spatial Surface Plasmon Polaritons , M. J. Ablowitz...temporal-spatial surface plasmon polaritons . Op- tics Communications, 330:49–55, 2014. 37 [39] M.C. Rechtsman, Y. Plotnik, J.M. Zeuner, , D. Song, Z...honeycomb lattices, M.J. Ablowitz and Y. Zhu, SIAM J. Appl. Math., Vol. 87 (2013) 1959-1979 11. Nonlinear Temporal-Spatial Surface Plasmon Polaritons

Real-Time Dosimetry and Optimization of Prostate Photodynamic Therapy

DTIC Science & Technology

2006-09-01

photodynamic therapy in patients with prostate cancer,” IPA 9th World Congress of Photodynamic Medicine, (2003). 2. Zhu TC, Diana S, Dimofte A...photodynamic therapy,” IPA 9th World Congress of Photodynamic Medicine, (2003). 3. Zhu TC, Altschuler M, Xiao Y, Finlay J, Dimofte A, Hahn SM, “Light...Optimization of treatment plan using Cimmino algorithm in prostate photodynamic therapy,” IPA 10th World Congress of Photodynamic Medicine, Munich

RLE (Research Laboratory of Electronics) Progress Report Number 130

DTIC Science & Technology

1988-07-01

Ippen, James G. Fujimoto, Wei-Zhu Lin, Beat Zysset, Robert W. Schoenlein, 4 Michael J. Lagasse The investigation of transient carrier dynamics in GaAs...G. Fujimoto, Wei-Zhu Lin, Reginald Birngruber, Beat Zysset, Robert W. Schoenleln Working in collaboration with researchers at the Massachusetts Eye... Binaural Hearing National Institutes of Health (Grant 5 RO 1 NS 10916) H. Steven Colburn, Nathaniel 1. Durlach, Patrick M. Zurek 17 Brooklyn College14 141

Genetics Home Reference: Bosma arhinia microphthalmia syndrome

MedlinePlus

... Xue S, Yigit G, Filali H, Chen K, Rosin N, Yoshiura KI, Oufadem M, Beck TJ, McGowan R, ... AD, Nürnberg P, Meschede D, Mühlbauer W, Okamoto N, Varghese V, Irving R, Sigaudy S, Williams D, Ahmed ...

Socioeconomic gradient in health in Canada: Is the gap widening or narrowing?

PubMed

Hajizadeh, Mohammad; Mitnitski, Arnold; Rockwood, Kenneth

2016-09-01

Notwithstanding a general improvement in health status, the socioeconomic gradient in health remains a public health challenge worldwide. Using longitudinal data from the National Population Health Survey (NPHS, n=17,276), we examined trends in socioeconomic gradients in two health indicators, viz. the Health Utility Index (HUI) and the Frailty Index (FI), among Canadian adults (25 years and older) between 1998/9-2010/11. The relative and slope indices of inequality (RII and SII, respectively) were employed to summarize income- and education-based inequality in the FI and the HUI in Canada as whole, and in five regions: the Atlantic provinces, Quebec, Ontario, the Prairies and British Columbia. We found that education- and income-related inequalities in health were present in all five regions of Canada. The estimated RIIs and SIIs suggested that education-related inequalities in the FI and the HUI increased among women. The results also revealed that relative and absolute income-related inequalities in the HUI increased in Canada, especially among women. Both absolute and relative inequalities indicated that income-related inequalities in the HUI increased in Quebec and in the Prairies over time. Persistent and growing socioeconomic inequalities in health in Canada over the past one and half decades should warrant more attention. The mechanisms underlying socioeconomic-related inequalities in Canada are less clear. Therefore, further studies are required to identify effective polices to reduce the socioeconomic gradient in health in Canada. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

[Exploration and analysis of the thought of medical education in the Shanghai New Chinese Medical College].

PubMed

Li, Ming; Shang, Li; Bing, Shoulan

2014-11-01

Shanghai New Chinese Medical College set up by Zhu Nanshan and his sons, Zhu Xiaonan and Zhu Hegao, was a medical college of traditional Chinese medicine (TCM) with the most innovative spirit in modern time. Its affiliated research institute held the principle of "realizing the scientific truth of TCM, training TCM advanced talents", marking the beginning of the pioneering of "scientific TCM". The educational plan, clinical research and academic organization based on "carrying forward the quintessence of Chinese culture, absorbing and digesting the new knowledge" showed a certain influence at home and abroad. The College advocated the combination of communicating with famous physicians and the study of theory, cultivation of students' organization and academic society, launching of journals, and organizing students' research associations was aiming at the satisfaction of the social needs and teaching orientation. Its running experience provided useful reference for modern TCM medical education.

PTEN Loss Antagonizes Calcitriol-Mediated Growth Inhibition in Prostate Epithelial Cells

DTIC Science & Technology

2009-05-01

deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci U S A, 98: 11450-11455, 2001. 27. Vlahos , C. J., Matter, W. F., Hui, K...and in aging skin in vivo. Proc Natl Acad Sci U S A, 92: 9363-9367, 1995. 35. Vlahos , C. J., Matter, W. F., Hui, K. Y., and Brown, R. F. A specific

Annual Adult Education Research Conference (AERC) Proceedings (31st, Athens, Georgia, May 18-20, 1990).

ERIC Educational Resources Information Center

Kleiber, Pam, Comp.; Tisdell, Libby, Comp.

The proceedings contains: "Extending Equality" (Armstrong); "Phenomenology of Emergent Meaning from Dialectical Questioning and Answering in Adult Learning (AL)" (Xue-Ming Bao); "Study of Structural Dimensions and Predictive Capability of Adult Attitudes toward Continuing Education Scale and Education Participation Scale" (Blunt); "Ideological and…

A new species of Aculops (Acari: Prostigmata: Eriophyidae) from Serbia on Dipsacus laciniatus L. (Dipsacaceae), a weed target of classical biological control in the United States of America

USDA-ARS?s Scientific Manuscript database

The new eriophyid mite species Aculops dipsaci n. sp. (Acari: Prostigmata: Eriophyidae) collected from Dipsacus laciniatus L. (Dipsacaceae) in northern Serbia is described and illustrated. Differential diagnosis is provided in comparison with Aculops salixis Xue, Song and Hong. This is the first e...

Is Best-Worst Scaling Suitable for Health State Valuation? A Comparison with Discrete Choice Experiments.

PubMed

Krucien, Nicolas; Watson, Verity; Ryan, Mandy

2017-12-01

Health utility indices (HUIs) are widely used in economic evaluation. The best-worst scaling (BWS) method is being used to value dimensions of HUIs. However, little is known about the properties of this method. This paper investigates the validity of the BWS method to develop HUI, comparing it to another ordinal valuation method, the discrete choice experiment (DCE). Using a parametric approach, we find a low level of concordance between the two methods, with evidence of preference reversals. BWS responses are subject to decision biases, with significant effects on individuals' preferences. Non parametric tests indicate that BWS data has lower stability, monotonicity and continuity compared to DCE data, suggesting that the BWS provides lower quality data. As a consequence, for both theoretical and technical reasons, practitioners should be cautious both about using the BWS method to measure health-related preferences, and using HUI based on BWS data. Given existing evidence, it seems that the DCE method is a better method, at least because its limitations (and measurement properties) have been extensively researched. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of administration

PubMed Central

Chen, Feng; Li, Li; Xu, Fang; Sun, Yan; Du, Feifei; Ma, Xutao; Zhong, Chenchun; Li, Xiuxue; Wang, Fengqing; Zhang, Nating; Li, Chuan

2013-01-01

BACKGROUND AND PURPOSE Flavonols and terpene lactones are putatively responsible for the properties of Ginkgo biloba leaf extracts that relate to prevention and treatment of cardiovascular disease and cerebral insufficiency. Here, we characterized rat systemic and cerebral exposure to these ginkgo compounds after dosing, as well as the compounds’ pharmacokinetics. EXPERIMENTAL APPROACH Rats received single or multiple doses of ShuXueNing injection (prepared from GBE50 for intravenous administration) or GBE50 (a standardized extract of G. biloba leaves for oral administration). Brain delivery of the ginkgo compounds was assessed with microdialysis. Various rat samples were analysed using liquid chromatography/mass spectrometry. KEY RESULTS Slow terminal elimination features of the flavonols counterbalanced the influence of poor oral bioavailability on their systemic exposure levels, which also resulted in significant accumulation of the compounds in plasma during the subchronic treatment with ShuXueNing injection and GBE50. Unlike the flavonols, the terpene lactones had poor enterohepatic circulation due to their rapid renal excretion and unknown metabolism. The flavonol glycosides occurred as major forms in plasma after dosing with ShuXueNing injection, while the flavonol aglycone conjugates were predominant in plasma after dosing with GBE50. Cerebral exposure was negligible for the flavonols and low for the terpene lactones. CONCLUSION AND IMPLICATIONS Unlike the significant systemic exposure levels, the levels of cerebral exposure to the flavonols and terpene lactones are low. The elimination kinetic differences between the two classes of ginkgo compounds influence their relative systemic exposure levels. The information gained is relevant to linking ginkgo administration to the medicinal effects. PMID:23808355

Checkpoint Pathways Activated by Re-Replication in Breast Cancer Cells

DTIC Science & Technology

2011-05-01

107- 13. 9. Zhu W DA. An ATR- and BRCA1-Mediated Fanconi Anemia Pathway Is Required for Activating the G2/M Checkpoint and DNA Damage Repair upon...re-replication. J Biol Chem 2007;282:30357-62. 25. Montes de Oca R, Andreassen PR, Margossian SP, et al. Regulated interaction of the Fanconi anemia ...protein, FANCD2, with chromatin. Blood 2005;105:1003-9. 26. Zhu W DA. An ATR- and BRCA1-Mediated Fanconi Anemia Pathway Is Required for Activating

Kevlar Vest Protection against Blast Overpressure Brain Injury: Systemic Contributions to Injury Etiology

DTIC Science & Technology

2015-07-01

F. S., Invest. Ophthal- mol. Vis. Sci. 2003, 44, 3219–3225. [52] Sun , Y., Jin , K., Xie, L., Childs, J., Mao, X. O., Logvinova, A., Greenberg, D. A...traumatic stress disorder (PTSD) within the Department of Defense. Clin. Neuropsychol. 23, 1291–1298. Jin , K., Zhu, Y., Sun , Y., Mao, X. O., Xie, L., and...task-specific neurobehavioral experience. Neurosci. Lett. 431, 226–230. Jin , K., Zhu, Y., Sun , Y., Mao, X. O., Xie, L., and Greenberg, D. A. (2002

China’s Muslims: Separatism and Prospects for Ethnic Peace

DTIC Science & Technology

2006-09-01

Management and Budget, Paperwork Reduction Project (0704-0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE September...unlike Uighur ethnic identity, Hui identity stems from and is compatible with the PRC and Chinese society. This study uses primary sources including...and is compatible with the PRC and Chinese society. This study uses primary sources including interviews with Uighurs, Hui and Han Chinese conducted

The IEEE International Conference on Data Mining (10th) Held in Sydney, Australia on 14-17 December 2010

DTIC Science & Technology

2010-12-17

Approach to Modeling Personalized Contexts of Mobile Users Tengfei Bao, Happia Cao, Enhong Chen, Jilei Tian, and Hui Xiong q Fast and Flexible...Kutsuna q Detecting Blackhole and Volcano Patterns in Directed Networks Zhongmou Li, Hui Xiong , Yanchi Liu, and Aoying Zhou q Exploiting Local Data...Density-Based Network Clustering via Structure-Connected Tree Division or Agglomeration Heli Sun, Jianbin Huang, Jiawei Han, Hongbo Deng, Peixiang Zhao

[The relationship between acupuncture-moxibustion theory of DOU Hanqing and Neo- Confucianism].

PubMed

Li, Baojin; Huang, Longxiang

2018-02-12

For the construction factors of acupuncture-moxibustion theory of DOU Hanqing , a doctor in Jin-Yuan Dynasty, we studied his life, acupuncture-moxibustion theory and culture background in the History of Medicine and Philosophy of Science & Technology. It was found that the major source of DOU Hanqing ' s Confucianism was the CHENG - ZHU Neo-Confucianism. The data show that Neo-Confucianism played an important role in the enrichment of his human nature, spirit, moral cultivation and political talent, making him a scholar in the Jin - Yuan dynasty, also shaping his medical ethics, medical skill and acupuncture-moxibustion theory. The inheritance, development and application of CHENG - ZHU Neo-Confucianism provided the most fundamental thinking, research methods and patterns for DOU Hanqing to interpret the acupuncture classics, summarize his teachers' experience and develop his theoretical system. DOU Hanqing ' s acupuncture-moxibustion practice and theory reached a new level, because he took acupuncture-moxibustion as one of the knowledge investigation and attainment of CHENG - ZHU Neo-Confucianism.

Exosomes from iPSCs Delivering siRNA Attenuate Intracellular Adhesion Molecule-1 Expression and Neutrophils Adhesion in Pulmonary Microvascular Endothelial Cells.

PubMed

Ju, Zhihai; Ma, Jinhui; Wang, Chen; Yu, Jie; Qiao, Yeru; Hei, Feilong

2017-04-01

The pro-inflammatory activation of pulmonary microvascular endothelial cells resulting in continuous expression of cellular adhesion molecules, and subsequently recruiting primed neutrophils to form a firm neutrophils-endothelium (PMN-EC) adhesion, has been examined and found to play a vital role in acute lung injury (ALI). RNA interference (RNAi) is a cellular process through harnessing a natural pathway silencing target gene based on recognition and subsequent degradation of specific mRNA sequences. It opens a promising approach for precision medicine. However, this application was hampered by many obstacles, such as immunogenicity, instability, toxicity problems, and difficulty in across the biological membrane. In this study, we reprogrammed urine exfoliated renal epithelial cells into human induced pluripotent stem cells (huiPSCs) and purified the exosomes (Exo) from huiPSCs as RNAi delivery system. Through choosing the episomal system to deliver transcription factors, we obtained a non-integrating huiPSCs. Experiments in both vitro and vivo demonstrated that these huiPSCs possess the pluripotent properties. The exosomes of huiPSCs isolated by differential centrifugation were visualized by transmission electron microscopy (TEM) showing a typical exosomal appearance with an average diameter of 122 nm. Immunoblotting confirmed the presence of the typical exosomal markers, including CD63, TSG 101, and Alix. Co-cultured PKH26-labeled exosomes with human primary pulmonary microvascular endothelial cells (HMVECs) confirmed that they could be internalized by recipient cells at a time-dependent manner. Then, electroporation was used to introduce siRNA against intercellular adhesion molecule-1 (ICAM-1) into exosomes to form an Exo/siRNA compound. The Exo/siRNA compound efficiently delivered the target siRNA into HMVECs causing selective gene silencing, inhibiting the ICAM-1 protein expression, and PMN-EC adhesion induced by lipopolysaccharide (LPS). These data suggest

Prevalence of visual impairment and refractive errors among different ethnic groups in schoolchildren in Turpan, China.

PubMed

Chin, Man Pan; Siong, Kar Ho; Chan, Ka Ho; Do, Chi Wai; Chan, Henry Ho Lung; Cheong, Allen Ming Yan

2015-05-01

There is currently limited information about ethnic differences in myopia prevalence within mainland China, especially in rural or semi-rural areas. We examined the prevalence of refractive errors, visual impairment and spectacle coverage in school children of varying ethnicity in Turpan, Xinjiang province. A community eye care service was provided for five schools. Presenting monocular distance and near visual acuity (VA), and ocular alignment were assessed. Retinoscopy and cycloplegic subjective refraction were performed for participants with presenting visual impairment (distance VA worse than 0.3 logMAR; Snellen 6/12 or 20/40) or abnormal binocular vision. Questionnaires administered prior to the eye examinations were used to collect information regarding personal lifestyle and parental myopia. A total of 646 out of 690 (94%) subjects aged four to 19 years (11.9 ± 2.6; mean ± S.D.) completed the eye examination. Three hundred and eighty-two (59%) of participants were of Uyghur ethnicity, followed by Han, 176 (27%) and Hui, 74 (12%). The mean age of Uyghur, Han and Hui students was 12.3 ± 2.7, 11.4 ± 2.6 and 11.4 ± 2.3 years respectively, in which the Uyghur students were significantly older than the Han and Hui students (F(3,631) = 5.58 p < 0.001). In total, 170 (27%) and 85 (13%) subjects failed the screening examination for one eye or both eyes, respectively. The prevalence of presenting visual impairment was not significantly different among the ethnic groups (p = 0.26). After cycloplegic refraction, most subjects' VA (98%) improved to better than 0.3 logMAR (Snellen 6/12 or 20/40). The prevalence of "clinically-significant myopia" (≤-0.50 dioptres) was 27%, 18% and 13% in Han, Hui and Uyghur children, respectively (p < 0.001). In contrast, Uyghur students had the highest prevalence of astigmatism (Uyghur 12%, Han 5%, Hui 4%). The overall spectacle coverage was 36%, while spectacle coverage among ethnic groups were similar (Han, 41%; Uyghur, 32%; Hui

Hole and Electron Extraction Layers Based on Graphene Oxide Derivatives for High-Performance Bulk Heterojunction Solar Cells

DTIC Science & Technology

2012-01-01

Yuhua Xue , Yunxiang Gao , Dingshan Yu , Michael Durstock , and Liming Dai * Hole and Electron Extraction Layers Based on Graphene Oxide...H. Wu , L. Chen , S. Su , Y. Cao , Adv. Mater. 2011 , 23 , 4636 . [ 29 ] T.-Y. Chu , S.-W. Tsang , J. Zhou , P. G. Verly , J

Estimation of Ocean and Seabed Parameters and Processes Using Low Frequency Acoustic Signals

DTIC Science & Technology

2012-09-30

were recently acquired under the DURIP program. 3. Finite Element Modeling of wave propagation: Doctoral student, Hui- Kwan Kim, is modeling wave...Delaware), Kevin Smith (Naval Postgraduate School), Dr. James F. Lynch and Dr. Y.-T. Lin (Woods Hole Oceanographic Institution). Another graduate student...test was conducted in collaboration with ARL, UT (Preston Wilson, PI) in August, 2011 in Narragansett Bay and off Block Island. PhD student Hui- Kwan

Estimation of Ocean and Seabed Parameters and Processes Using Low Frequency Acoustic Signals

DTIC Science & Technology

2011-09-01

Dr. Mohsen Badiey (University of Delaware), Kevin Smith (Naval Postgraduate School), Dr. James F. Lynch and Dr. Y.-T. Lin (Woods Hole Oceanographic...Wilson (ARL, University of Texas) in this topic. 3. Finite Element Modeling of wave propagation: Doctoral student, Hui- Kwan Kim, is modeling wave...student Hui- Kwan Kim is focusing on finite element modeling of wave propagation. RESULTS 1. Acoustic variability in the presence of internal waves

Parental Perceptions of Quality of Life in Children on Long-Term Ventilation at Home as Compared to Enterostomy Tubes.

PubMed

Redouane, Brahim; Cohen, Eyal; Stephens, Derek; Keilty, Krista; Mouzaki, Marialena; Narayanan, Unni; Moraes, Theo; Amin, Reshma

2016-01-01

Health related quality of life (HRQL) of children using medical technology at home is largely unknown. Our aim was to examine the HRQL in children on long-term ventilation at home (LTHV) in comparison to a cohort using an enterostomy tube. Participants were divided into three groups: 1) LTHV without an enterostomy tube (LTHV cohort); 2) Enterostomy tube (GT cohort); 3) LTHV with an enterostomy tube (LTHV+GT cohort). Caregivers of children ≥ 5 years and followed at SickKids, Toronto, Canada, completed three questionnaires: Health Utilities Index 2/3 (HUI2/3), Caregiver Priorities Caregiver Health Index (CPCHILD), and the Paediatric Quality of Life Inventory (PedsQL). The primary outcome was the difference in utility (HUI2/3) scores between the cohorts. One hundred and nineteen children were enrolled; 47 in the LTHV cohort, 44 in the GT cohort, and 28 in the LTHV+GT cohort. In univariate analysis, HUI2 mean (SE) scores were lowest for the GT cohort, 0.4 (0.04) followed by the LTHV+GT, 0.42 (0.05) and then the LTHV cohort, 0.7 (0.04), p = 0.001. A similar trend was seen for the HUI3 mean (SE) scores: GT cohort, 0.1 (0.06), followed by the LTHV +GT cohort, 0.2 (0.08) and then the LTHV cohort, 0.5 (0.06), p = 0.0001. Technology cohort, nursing hours and the severity of health care needs predicted HRQL as measured by the HUI2/3. The HRQL of these children is low. Children on LTHV had higher HRQL than children using enterostomy tubes. Further work is needed to identify modifiable factors that can improve HRQL.

Realization of New and Enhanced Materials Properties Through Nanostructural Control

DTIC Science & Technology

2006-05-15

34 Proc. SPIE, 6014, 60140P-1-15 (2005). 57. C. Zhang, S. S. Sun, C. E. Bonner, S. Kim, H. R. Fetterman , and L. R. Dalton, "Polymer Materials for...Wang, J. Zhu, M. He, Y. Ra, S. S. H. Mao, A. W. Harper, L. R. Dalton, and H. R. Fetterman , "Low Vn High Thermal Stability Electro Optic Polymer...H. Zhang, S. M. Garner, S. S. Lee, W. H. Steier, J. Chen, F. Wang, J. Zhu, M. He, Y. Ra, S. S. Mao, A. W. Harper, L. R. Dalton, and H. R. Fetterman

Forensic ancestry analysis in two Chinese minority populations using massively parallel sequencing of 165 ancestry-informative SNPs.

PubMed

He, Guanglin; Wang, Zheng; Wang, Mengge; Luo, Tao; Liu, Jing; Zhou, You; Gao, Bo; Hou, Yiping

2018-06-04

Ancestry inference based on single nucleotide polymorphism (SNP) with marked allele frequency differences in diverse populations (called ancestry-informative SNP, AISNP) is rapidly developed with the technology advancements of massively parallel sequencing (MPS). Despite the decade of exploration and broad public interest in the peopling of East-Asians, the genetic landscape of Chinese Silk Road populations based on the AISNPs is still little known. In this work, 206 unrelated individuals from Chinese Uyghur and Hui populations were firstly genotyped by 165 AISNPs (The Precision ID Ancestry Panel) using the Ion Torrent PGM system. The ethnic origin of two investigated populations and population structures and genetic relationships were subsequently investigated. The 165 AISNPs panel not only can differentiate Uyghur and Hui populations but also has potential applications in individual identification. Comprehensive population comparisons and admixture estimates demonstrated a predominantly higher European-related ancestry (36.30%) in Uyghurs than Huis (3.66%). Overall, the Precision ID Ancestry Panel can provide good resolution at the intercontinental level, but has limitations on the genetic homogeneous populations, such as the Hui and Han. Additional population-specific AISNPs remain necessary to get better-scale resolution within geographically proximate populations in East Asia. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Comparing and explaining differences in the magnitude, content, and sensitivity of utilities predicted by the EQ-5D, SF-6D, HUI 3, 15D, QWB, and AQoL-8D multiattribute utility instruments.

PubMed

Richardson, Jeff; Khan, Munir A; Iezzi, Angelo; Maxwell, Aimee

2015-04-01

Cost utility analysis permits the comparison of disparate health services by measuring outcomes in comparable units, namely, quality-adjusted life-years, which equal life-years times the utility of the health state. However, comparability is compromised when different utility instruments predict different utilities for the same health state. The present paper measures the extent of, and reason for, differences between the utilities predicted by the EQ-5D-5L, SF-6D, HUI 3, 15D, QWB, and AQoL-8D. Data were obtained from patients in seven disease areas and members of the healthy public in six countries. Differences between public and patient utilities were estimated using each of the instruments. To explain discrepancies between the estimates, the measurement scales and content of the instruments were compared. The sensitivity of instruments to independently measured health dimensions was measured in pairwise comparisons of all combinations of the instruments. The difference between public and patient utilities varied with the choice of instrument by more than 50% for every disease group and in four of the seven groups by more than 100%. Discrepancies were associated with differences in both the instrument content and their measurement scales. Pairwise comparisons of instruments found that variation in the sensitivity to physical and psychosocial dimensions of health closely reflected the items in the instrument's descriptive systems. Results indicate that instruments measure related but different constructs. They imply that commonly used instruments systematically discriminate against some classes of services, most notably mental health services. Differences in the instrument scales imply the need for transformations between the instruments to increase the comparability of measurement. © The Author(s) 2014.

Investigation of Rho Signaling Pathways in 3-D Collagen Matrices with Multidimensional Microscopy and Visualization Techniques

DTIC Science & Technology

2008-03-01

most prevalent cancer among women .1 Therefore, tech- ologies to detect, classify, study, and combat breast cancer re of great significance. Among these...M. Sidani , J. Wyckoff, C. Xue, J. E. Segall, and J. Condeelis, “Prob- ing the microenvironment of mammary tumors using multiphoton microscopy,” J

A Cultural Model of Learning: Chinese "Heart and Mind for Wanting T Learn."

ERIC Educational Resources Information Center

Li, Jin

2002-01-01

Examined the Chinese model of learning using the Chinese term, "hao-xue-xin" (heart and mind for wanting to learn.) College students described ideal learners. They considered learning a process of moral striving (self-perfection) that stressed seeking knowledge and cultivating passion for lifelong learning, fostering diligence, enduring…

Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of administration.

PubMed

Chen, Feng; Li, Li; Xu, Fang; Sun, Yan; Du, Feifei; Ma, Xutao; Zhong, Chenchun; Li, Xiuxue; Wang, Fengqing; Zhang, Nating; Li, Chuan

2013-09-01

Flavonols and terpene lactones are putatively responsible for the properties of Ginkgo biloba leaf extracts that relate to prevention and treatment of cardiovascular disease and cerebral insufficiency. Here, we characterized rat systemic and cerebral exposure to these ginkgo compounds after dosing, as well as the compounds' pharmacokinetics. Rats received single or multiple doses of ShuXueNing injection (prepared from GBE50 for intravenous administration) or GBE50 (a standardized extract of G. biloba leaves for oral administration). Brain delivery of the ginkgo compounds was assessed with microdialysis. Various rat samples were analysed using liquid chromatography/mass spectrometry. Slow terminal elimination features of the flavonols counterbalanced the influence of poor oral bioavailability on their systemic exposure levels, which also resulted in significant accumulation of the compounds in plasma during the subchronic treatment with ShuXueNing injection and GBE50. Unlike the flavonols, the terpene lactones had poor enterohepatic circulation due to their rapid renal excretion and unknown metabolism. The flavonol glycosides occurred as major forms in plasma after dosing with ShuXueNing injection, while the flavonol aglycone conjugates were predominant in plasma after dosing with GBE50. Cerebral exposure was negligible for the flavonols and low for the terpene lactones. Unlike the significant systemic exposure levels, the levels of cerebral exposure to the flavonols and terpene lactones are low. The elimination kinetic differences between the two classes of ginkgo compounds influence their relative systemic exposure levels. The information gained is relevant to linking ginkgo administration to the medicinal effects. © 2013 The Authors. British Journal of Pharmacology published by John Wiley &. Sons Ltd on behalf of The British Pharmacological Society.

[Comparison of the compilation features of Science of Meridians and Acupoints among different editions].

PubMed

Chen, Xiaojun

The compilation features of Jingluo Shuxue Xue ( Science of Meridians and Acupoints ) among different editions were summarized and analyzed. Jingluo Xue ( Science of Meridians ) and Shuxue Xue ( Science of Acupoints ) published by Shanghai Scientific and Technical Publishers in 1984 are the pioneer as the textbook for the education of acupuncture discipline for the bachelor degree, but there is the big controversy for the editions in 1996. These two books were combined as one, titled Science of Meridians and Acupoints , 2013 edition, published by China Press of Traditional Chinese Medicine. It is concise and coherent in content and is regarded as the milestone in the history of textbook compilation. This book was re-edited in 2007 without major changes in content. The one in 2009 was revised a lot on the basis of the original several editions, published by Shanghai Scientific and Technical Publishers. But unfortunately, it did not bring the big impacts in China. The edition in 2012, published by China Press of Traditional Chinese Medicine had made the innovations besides integrating the achievements of the previous editions, characterized as preciseness and conciseness. By contrast, the edition in 2012, published by People's Medical Publishing House was accomplished by simple modification on the basis of the editions in 2003 and in 2007, without great innovation. Regarding the on-going publication of the textbooks in "the 13th five-year plan", it is viewed that the new edition of textbook should maintain the general framework of "the 12th five-year plan", based on which, a few questions should be revised appropriately. Additionally, "less words, more illustration" should be the basic principle for the revision of the new edition.

Influence of Multi-Walled Carbon Nanotubes on the Thermal and Mechanical Behavior of Carbon/Epoxy Composites (Preprint)

DTIC Science & Technology

2007-03-01

Stephenson Chemical Company, Inc. Carbon Nanotechnologies , Inc. 3 produced the multi-walled carbon nanotubes used in this study. The tube diameters range...5125-5132. 11. Kim S. , Pechar T. W. and Marand E., Desalination , 192(2006): 330-339 12. Cai H., Yan F. Y., and Xue Q. J., Materials Science and

Negativity Bounds for Weyl-Heisenberg Quasiprobability Representations

NASA Astrophysics Data System (ADS)

DeBrota, John B.; Fuchs, Christopher A.

2017-08-01

The appearance of negative terms in quasiprobability representations of quantum theory is known to be inevitable, and, due to its equivalence with the onset of contextuality, of central interest in quantum computation and information. Until recently, however, nothing has been known about how much negativity is necessary in a quasiprobability representation. Zhu (Phys Rev Lett 117 (12):120404, 2016) proved that the upper and lower bounds with respect to one type of negativity measure are saturated by quasiprobability representations which are in one-to-one correspondence with the elusive symmetric informationally complete quantum measurements (SICs). We define a family of negativity measures which includes Zhu's as a special case and consider another member of the family which we call "sum negativity." We prove a sufficient condition for local maxima in sum negativity and find exact global maxima in dimensions 3 and 4. Notably, we find that Zhu's result on the SICs does not generally extend to sum negativity, although the analogous result does hold in dimension 4. Finally, the Hoggar lines in dimension 8 make an appearance in a conjecture on sum negativity.

[Prevalence of anemia and its association with nutritional status among Chinese students of ethnic minorities in 2010].

PubMed

Song, Y; Zhang, B; Hu, P J; Ma, J

2016-06-18

To analyze the prevalence of anemia and its proportions of severity, and to examine the association between anemia and nutritional status among Chinese students of ethnic minorities, so as to provide bases for the prevention and treatment of anemia. The subjects were Mongolian, Hui, Zhuang and Korean students aged 7, 9, 12, 14 and 17 years, sampled from the 2010 Chinese National Surveys on Students' Constitution and Health. World Health Organization (WHO) criteria for screening anemia (2001) was used, and the proportion rates of mild, moderate and severe were analyzed. The nutritional status was defined according to the growth references of body mass index (BMI)-for-age z-score for 5-19 years developed by the WHO. Stepwise Logistic regression was used to assess the association between anemia and nutritional status, gender, urban/rural areas, age and ethnic minorities. The prevalences of anemia were 4.4%, 26.4%, 6.6% and 5.8% in Mongolian, Hui, Zhuang and Korean students, respectively, of whom, the prevalence of anemia was highest in rural girls and reached 4.8%, 42.0%, 9.0% and 6.7%, respectively. Most of the ethnic minorities' students belonged to mild anemia, and the prevalence of severe anemia was 1.4%, 12.9%, 1.6% and 1.9% in Mongolian, Hui, Zhuang and Korean students, respectively. Stepwise Logistic regression showed that the girls, rural students, students aged 12 years and 17 years, Hui, Zhuang and Korean students were more likely to develop anemia than the boys, urban students, students aged 7 years and Mongolian students. The overweight students were less likely to develop anemia compared with the normal students and there was no significant association between anemia and thinness or obesity when the other factors were controlled (P>0.05). The epidemic of anemia was different in the different ethnic minorities and the prevalence of anemia in Hui students was of moderate public health concern according to the WHO's criteria. We should pay more attention to

Drug Development and Conservation of Biodiversity in West and Central Africa: Performance of Neurochemical and Radio Receptor Assays of Plant Extracts Drug Discovery for the Central Nervous System

DTIC Science & Technology

2004-09-01

7) Hui, D.; Sao-Xing, C. J. Nat. Prod. 1998, 61, 142-144. (8) Aldrich Libray of 13C and 1H FT NMR spectra 1992, 2, 326A. (9) Kadota, S .; Hui, D...Biodiversity in West and Central Africa: Performance of Neurochemical and Radio Receptor Assays of Plant Extracts Drug Discovery for the Central... s ) and should not be construed as an official Department of the Army position, policy or decision unless so designated by other documentation

A comparison of the relationships between psychosocial factors, occupational strain, and work ability among 4 ethnic teacher groups in China.

PubMed

Lian, Yulong; Xiao, Jing; Zhang, Chen; Guan, Suzhen; Li, Fuye; Ge, Hua; Liu, Jiwen

2016-01-01

The present study compared the level of occupational strain and work ability among Han, Hui, Uygur, Hui, and Kazakh teachers, and explored ethnic differences based on the associations of psychosocial factors at work, occupational strain, and work ability. A cross-sectional survey was conducted among 2,941 teachers in primary and secondary schools in Xinjiang Province, China. Psychosocial factors, occupational strain, and work ability were measured using the Occupation Stress Inventory-Revised Edition (OSI-R) and Work Ability Index. Han and Hui teachers experienced reduced work ability compared with Uygur and Kazakh teachers, and this finding was caused, in part, by exposure to psychosocial factors at work. The vocational and psychological strains caused by these factors play an important role in reduced work ability among all ethnic teacher groups. The findings indicate the importance of taking action to reduce occupational strain for promoting teachers' work ability in multiethnic workplaces.

Comparison of direct and indirect methods of estimating health state utilities for resource allocation: review and empirical analysis.

PubMed

Arnold, David; Girling, Alan; Stevens, Andrew; Lilford, Richard

2009-07-22

Utilities (values representing preferences) for healthcare priority setting are typically obtained indirectly by asking patients to fill in a quality of life questionnaire and then converting the results to a utility using population values. We compared such utilities with those obtained directly from patients or the public. Review of studies providing both a direct and indirect utility estimate. Papers reporting comparisons of utilities obtained directly (standard gamble or time tradeoff) or indirectly (European quality of life 5D [EQ-5D], short form 6D [SF-6D], or health utilities index [HUI]) from the same patient. PubMed and Tufts database of utilities. Sign test for paired comparisons between direct and indirect utilities; least squares regression to describe average relations between the different methods. Mean utility scores (or median if means unavailable) for each method, and differences in mean (median) scores between direct and indirect methods. We found 32 studies yielding 83 instances where direct and indirect methods could be compared for health states experienced by adults. The direct methods used were standard gamble in 57 cases and time trade off in 60(34 used both); the indirect methods were EQ-5D (67 cases), SF-6D (13), HUI-2 (5), and HUI-3 (37). Mean utility values were 0.81 (standard gamble) and 0.77 (time tradeoff) for the direct methods; for the indirect methods: 0.59(EQ-5D), 0.63 (SF-6D), 0.75 (HUI-2) and 0.68 (HUI-3). Direct methods of estimating utilities tend to result in higher health ratings than the more widely used indirect methods, and the difference can be substantial.Use of indirect methods could have important implications for decisions about resource allocation: for example, non-lifesaving treatments are relatively more favoured in comparison with lifesaving interventions than when using direct methods.

Exploration of Morbidity in a Serial Study of Long-Term Brain Tumor Survivors: A Focus on Pain.

PubMed

Nayiager, Trishana; Duckworth, JoAnn; Pullenayegum, Eleanor; Whitton, Anthony; Hollenberg, Robert; Horsman, John; Furlong, William; Spitzer, Rachel; Barr, Ronald

2015-09-01

Children surviving brain tumors are frequently identified as having substantially decreased health-related quality of life (HRQL) in cross-sectional studies. This study explored the HRQL of a cohort of such survivors, who were recruited as adolescents and followed for a decade, in order to determine the trajectory of their morbidities. Children diagnosed between January 1, 1985, and December 31, 1998, more than 2 years from diagnosis (N = 40), were recruited in 2000/2001 (T1) aged 16.74 ± 4.23 years. Health Utilities Index questionnaires (HUI2/3) were completed in 2000/2001 and again at 5 years (T2) and 10 years (T3), with 37 and 25 participants then aged 21.54 ± 4.29 and 27.97 ± 4.07 years, respectively. In addition to study subjects, parental proxies completed questionnaires at T1 and T2, while study subjects selected proxies at T3. Single attributes (domains/dimensions) of HRQL and details of pain were analyzed. Cognition was the attribute compromised most often (T1 = 66.7% of participants, T2 = 62.2%, T3 = 60.0%). Pain was also reported frequently (T1 = 35%, T2 = 25%, T3 = 52%), and at T3 correlated moderately with HUI2 sensation (0.77) and HUI3 vision (0.44), speech (0.51), and ambulation (0.50). The lower median utility score for pain at T3 than at T1/T2 was a clinically important difference. Severe pain was identified in the lower extremities, back, upper extremities, and abdomen. Morbidity was observed also in emotion (worry HUI2 and unhappiness HUI3), sensation, and vision. Decreased HRQL in survivors of brain tumors in childhood is multifaceted. Pain is a prominent burden, along with morbidity in cognition, emotion, sensation, and vision. Further studies should explore pain and neurologic deficits, and potential opportunities for therapeutic intervention.

lncRNA Structure: Message to the Heart.

PubMed

Fazal, Furqan M; Chang, Howard Y

2016-10-06

In this issue, Xue et al. (2016) describe the secondary structure of the heart-specific long non-coding RNA Braveheart, leading to the discovery of a short, asymmetric G-rich loop that controls cardiac lineage commitment by interacting with the transcription factor CNBP. Copyright © 2016 Elsevier Inc. All rights reserved.

Two new species of the stonefly genus Amphinemura (Insecta, Plecoptera, Nemouridae) from China.

PubMed

Ji, Xiao-Yu; Du, Yu-Zhou; Wang, Zhi-Jie

2014-01-01

Two new species of the genus Amphinemura Ris from China are described and illustrated, i.e. A. annulata Du & Ji, sp. n. from Zhejiang, Shanxi, Shaanxi and Guizhou Province, and A. lingulata Du & Wang, sp. n. from Shaanxi and Sichuan Province. A. annulata is similar to A. tricintusidens Wang & Zhu in having an apical cavity of the epiproct, but the epiproct ventral sclerite and the median paraproct lobe of the two species are different. A. lingulata is related to A. didyma Zhu & Yang in having the similar epiproct, but they differ mostly in paraproct median and outer lobes.

Two new species of the stonefly genus Amphinemura (Insecta, Plecoptera, Nemouridae) from China

PubMed Central

Ji, Xiao-Yu; Du, Yu-Zhou; Wang, Zhi-Jie

2014-01-01

Abstract Two new species of the genus Amphinemura Ris from China are described and illustrated, i.e. A. annulata Du & Ji, sp. n. from Zhejiang, Shanxi, Shaanxi and Guizhou Province, and A. lingulata Du & Wang, sp. n. from Shaanxi and Sichuan Province. A. annulata is similar to A. tricintusidens Wang & Zhu in having an apical cavity of the epiproct, but the epiproct ventral sclerite and the median paraproct lobe of the two species are different. A. lingulata is related to A. didyma Zhu & Yang in having the similar epiproct, but they differ mostly in paraproct median and outer lobes. PMID:24843269

Effects of 90-day feeding of transgenic Bt rice TT51 on the reproductive system in male rats.

PubMed

Wang, Er Hui; Yu, Zhou; Hu, Jing; Xu, Hai Bin

2013-12-01

Rice is a staple food crop; however, the threat of pests leads to a serious decline in its output and quality. The CryAb/CryAc gene, encodes a synthetic fusion Bacillus thuringiensis (Bt) crystal protein, was introduced into rice MingHui63 to produce insect-resistant rice TT51. This study was undertaken to investigate potential unintended effects of TT51 on the reproductive system in male rats. Male rats were treated with diets containing 60% of either TT51 or MingHui63 by weight, nutritionally balanced to an AIN93G diet, for 90days. An additional negative control group of rats were fed with a rice-based AIN93G diet. Body weights, food intake, hematology, serum chemistry, serum hormone levels, sperm parameters and relative organ/body weights were measured, and gross as well as microscopic pathology were examined. No diet-related significant differences in the values of response variables were observed between rats that were fed with diet containing transgenic TT51, MingHui63 and the control in this 90-day feeding study. In addition, necropsy and histopathology examination indicated no treatment-related changes. The results from the present study indicated that TT51 does not appear to exert any effect on the reproductive system in male rats compared with MingHui63 or the control. Copyright © 2013 Elsevier Ltd. All rights reserved.

Simultaneous determination of three alkaloids, four ginsenosides and limonin in the plasma of normal and headache rats after oral administration of Wu-Zhu-Yu decoction by a novel ultra fast liquid chromatography-tandem mass spectrometry method: application to a comparative pharmacokinetics and ethological study.

PubMed

Xu, Huarong; Li, Qing; Yin, Yidi; Lv, Chunxiao; Sun, Wanyang; He, Bosai; Liu, Ran; Chen, Xiaohui; Bi, Kaishun

2013-04-01

A novel, sensitive and reliable ultra fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) method has been developed and validated for simultaneous quantitation of eight main active ingredients (evodiamine, rutaecarpine, dehydroevodiamine, limonin, ginsenoside Rb1, Rd, Re and Rg1) in rat plasma after oral administration of Wu-Zhu-Yu (WZY) decoction, which is a celebrated and widely used Traditional Chinese Medicine formula for the treatment of headache. The analytes and internal standard (IS) were separated on a SHIM-PACK XR-ODS II column, and the detection was performed on a UFLC-MS/MS system with turbo ion spray source. The lower limits of quantification were 1.5, 0.5, 1.0, 2.0, 2.0, 1.0, 0.5 and 0.2 ng ml(-1) for evodiamine, rutaecarpine, dehydroevodiamine, limonin, gensenoside Rb1, Rd, Re and Rg1, respectively. Linearity, accuracy, precision and absolute recoveries of the eight analytes were all within satisfaction. The IS-normalized matrix factor was adopted for assessing the matrix effect and accompanied with a satisfactory result. The validated method has been successfully applied to compare pharmacokinetic profiles of the eight active ingredients in rat plasma between normal and headache rats after administration. Exact pharmaceutical effect of WZY decoction on headache was demonstrated by the ethological response of headache rats induced by nitric oxide donor after administration. The results indicated that the absorption of evodiamine, rutaecarpine, gensenoside Rb1, Re and Rg1 in headache group were significantly higher than those in normal group with similar concentration-time curves while no significant differences existed in limonin and ginsenoside Rd between the two groups. Copyright © 2013 John Wiley & Sons, Ltd.

Advanced Multi-Moment Microphysics for Precipitation and Tropical Cyclone Forecast Improvement within COAMPS

DTIC Science & Technology

2011-09-30

capable of predicting up to three moments of hydrometeor particle size distributions (PSDs) inside the Navy’s Coupled Ocean/Atmosphere Mesoscale...Sobash, P. T. Marsh, A. R. Dean, M. Xue, F. Kong, K. W. Thomas, J. Du, D. R. Novak, F. E. Barthold, M. J. Bodner, J. J. Levit , C. B. Entwistle, T. Jensen

Harnessing Autopsied DIPG Tumor Tissues for Orthotopic Xenograft Model Development in the Brain Stems of SCID Mice

DTIC Science & Technology

2012-09-01

patched-1-deficient mouse medulloblastoma . Cancer Res. 2009;69:4682-4690. 14. Mao XG, Zhang X, Xue XY, et al. Brain Tumor Stem-Like Cells Identified by...propagating cells in a mouse model of medulloblastoma . Cancer Cell. 2009;15:135-147. 16. Yagi H, Yanagisawa M, Suzuki Y, et al. HNK-1 epitope-carrying

PREFERENCE-BASED HEALTH-RELATED QUALITY OF LIFE OUTCOMES IN CHILDREN WITH AUTISM SPECTRUM DISORDERS: A COMPARISON OF GENERIC INSTRUMENTS

PubMed Central

Tilford, J. Mick; Payakachat, Nalin; Kovacs, Erica; Pyne, Jeffrey M.; Brouwer, Werner; Nick, Todd; Bellando, Jayne; Kuhlthau, Karen

2012-01-01

Background Cost-effectiveness analysis of pharmaceutical and other treatments for children with autism spectrum disorders (ASDs) has the potential to improve access to services by demonstrating the value of treatment to public and private payers, but methods for measuring quality adjusted life years (QALYs) in children are understudied. No cost-effectiveness analyses have been undertaken in this population using the cost per QALY metric. Objective This study describes health-related quality of life (HRQoL) outcomes in children with ASDs and compares the sensitivity of two generic preference-based instruments relative to ASD-related conditions and symptoms. Methods The study design was cross-sectional with prospectively collected outcome data that was correlated with retrospectively assessed clinical information. Subjects were recruited from two sites of the Autism Treatment Network (ATN): a developmental center in Little Rock, Arkansas, and an outpatient psychiatric clinic at Columbia University Medical Center in New York, NY. Children that met DSM-IV criteria for an ASD by a multi-disciplinary team evaluation were asked to participate in a clinical registry. Families of children with an ASD that agreed to be contacted about participation in future research studies as part of the ATN formed the sampling frame for the study. Families were included if the child with the ASD was between 4 and 17 years of age and the family caregiver spoke English. Eligible families were contacted by mail to see if they would be interested in participating in the study with N=150 completing surveys. HRQoL outcomes were described using the Health Utilities Index Mark III (HUI-3) and the self-administered Quality of Well-Being scale (QWB-SA) obtained by proxy via the family caregiver. Results Children were diagnosed as having autistic disorder (76%), pervasive developmental disorder (PDD-NOS) (15%), and Asperger's disorder (9%). Average HUI-3 and QWB-SA scores were 0.68 (SD=0.21, range

Comment on "An improved gray Lattice Boltzmann model for simulating fluid flow in multi-scale porous media": Intrinsic links between LBE Brinkman schemes

NASA Astrophysics Data System (ADS)

Ginzburg, Irina

2016-02-01

In this Comment on the recent work (Zhu and Ma, 2013) [11] by Zhu and Ma (ZM) we first show that all three local gray Lattice Boltzmann (GLB) schemes in the form (Zhu and Ma, 2013) [11]: GS (Chen and Zhu, 2008; Gao and Sharma, 1994) [1,4], WBS (Walsh et al., 2009) [12] and ZM, fail to get constant Darcy's velocity in series of porous blocks. This inconsistency is because of their incorrect definition of the macroscopic velocity in the presence of the heterogeneous momentum exchange, while the original WBS model (Walsh et al., 2009) [12] does this properly. We improve the GS and ZM schemes for this and other related deficiencies. Second, we show that the ;discontinuous velocity; they recover on the stratified interfaces with their WBS scheme is inherent, in different degrees, to all LBE Brinkman schemes, including ZM scheme. None of them guarantees the stress and the velocity continuity by their implicit interface conditions, even in the frame of the two-relaxation-times (TRT) collision operator where these two properties are assured in stratified Stokes flow, Ginzburg (2007) [5]. Third, the GLB schemes are presented in work (Zhu and Ma, 2013) [11] as the alternative ones to direct, Brinkman-force based (BF) schemes (Freed, 1998; Nie and Martys, 2007) [3,8]. Yet, we show that the BF-TRT scheme (Ginzburg, 2008) [6] gets the solutions of any of the improved GLB schemes for specific, viscosity-dependent choice of its one or two local relaxation rates. This provides the principal difference between the GLB and BF: while the BF may respect the linearity of the Stokes-Brinkman equation rigorously, the GLB-TRT cannot, unless it reduces to the BF via the inverse transform of the relaxation rates. Furthermore, we show that, in limited parameter space, ;gray; schemes may run one another. From the practical point of view, permeability values obtained with the GLB are viscosity-dependent, unlike with the BF. Finally, the GLB shares with the BF a so-called anisotropy (Ginzburg

Highly Crystalline and Low Bandgap Donor Polymers for Efficient Polymer Solar Cells

DTIC Science & Technology

2012-01-01

thanks Dr. Ina Martin and Dr. Yuhua Xue for technical support. Received: September 21, 2011 Published online: December 20, 2011 542 www.advmat.de...M. Chen, Y. Yang, Adv. Mater. 2009, 21, 4238. [12] E. G. Wang, L. Wang, L. F. Lan, C. Luo, W. L. Zhuang, J. B. Peng, Y. Cao , Appl. Phys. Lett. 2008

Hydrophilic Cucurbit[7]uril-Pseudorotaxane-Anchored-Monolayer-Protected Gold Nanorods

DTIC Science & Technology

2013-03-20

FULL PAPER DOI:10.1002/ejic.201300010 Hydrophilic Cucurbit[7]uril-Pseudorotaxane-Anchored- Monolayer-Protected Gold Nanorods Xiang Ma,[a] Yuhua Xue... Cao , Q. Wang, H. Tian, Chem. Commun. 2011, 47, 3559–3561. [8] a) I. Hwang, K. Baek, M. Jung, Y. Kim, K. M. Park, D. W. Lee, N. Selvapalam, K. Kim, J. Am

Embryonic ring closure: Actomyosin rings do the two-step

PubMed Central

2016-01-01

Actomyosin rings drive numerous closure processes, but the mechanisms by which they contract are still poorly understood. In this issue, Xue and Sokac (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201608025) show that actomyosin ring closure during Drosophila melanogaster cellularization uses two steps, only one of which involves Myosin-2. PMID:27799371

Magnetic nanorings and manipulation of nanowires

NASA Astrophysics Data System (ADS)

Chien, C. L.

2006-03-01

The properties of nanoscale entities, such as nanorings and nanowires, and the response of such entities to external fields are dictated by their geometrical shapes and sizes, which can be manipulated by fabrication. We have developed a method for fabricating a large number of nanorings (10^10) of different sizes in the range of 100 nm and ring cross sections. During magnetic reversal, both the vortex state and the rotating onion state appear with different proportions, which depend on the ring diameter, ring cross section, and the profile of the ring cross section. In the case of nanowires in suspension, the large aspect ratio of the nanowires can be exploited for manipulation despite extremely small Reynolds numbers of 10-5. Using AC electric field applied to microelectrodes, both magnetic and non-magnetic nanowires can be efficiently assembled into desired patterns. We also demonstrate rotation of nanowires with precisely controlled rotation speed and chirality, as well as an electrically driven nanowire micromotor a few in size. In collaboration with F. Q. Zhu, D. L. Fan, O. Tchernyshyov, R. C. Cammarata (Johns Hopkins University) and X. C. Zhu and J. G. Zhu (Carnegie-Mellon University).

Changes in quality of life into adulthood after very preterm birth and/or very low birth weight in the Netherlands

PubMed Central

2013-01-01

Background It is important to know the impact of Very Preterm (VP) birth or Very Low Birth Weight (VLBW). The purpose of this study is to evaluate changes in Health-Related Quality of Life (HRQoL) of adults born VP or with a VLBW, between age 19 and age 28. Methods The 1983 nationwide Dutch Project On Preterm and Small for gestational age infants (POPS) cohort of 1338 VP (gestational age <32 weeks) or VLBW (<1500 g) infants, was contacted to complete online questionnaires at age 28. In total, 33.8% of eligible participants completed the Health Utilities Index (HUI3), the London Handicap Scale (LHS) and the WHOQoL-BREF. Multiple imputation was applied to correct for missing data and non-response. Results The mean HUI3 and LHS scores did not change significantly from age 19 to age 28. However, after multiple imputation, a significant, though not clinically relevant, increase of 0.02 on the overall HUI3 score was found. The mean HRQoL score measured with the HUI3 increased from 0.83 at age 19 to 0.85 at age 28. The lowest score on the WHOQoL was the psychological domain (74.4). Conclusions Overall, no important changes in HRQoL between age 19 and age 28 were found in the POPS cohort. Psychological and emotional problems stand out, from which recommendation for interventions could be derived. PMID:23531081

Using Linear Equating to Map PROMIS(®) Global Health Items and the PROMIS-29 V2.0 Profile Measure to the Health Utilities Index Mark 3.

PubMed

Hays, Ron D; Revicki, Dennis A; Feeny, David; Fayers, Peter; Spritzer, Karen L; Cella, David

2016-10-01

Preference-based health-related quality of life (HR-QOL) scores are useful as outcome measures in clinical studies, for monitoring the health of populations, and for estimating quality-adjusted life-years. This was a secondary analysis of data collected in an internet survey as part of the Patient-Reported Outcomes Measurement Information System (PROMIS(®)) project. To estimate Health Utilities Index Mark 3 (HUI-3) preference scores, we used the ten PROMIS(®) global health items, the PROMIS-29 V2.0 single pain intensity item and seven multi-item scales (physical functioning, fatigue, pain interference, depressive symptoms, anxiety, ability to participate in social roles and activities, sleep disturbance), and the PROMIS-29 V2.0 items. Linear regression analyses were used to identify significant predictors, followed by simple linear equating to avoid regression to the mean. The regression models explained 48 % (global health items), 61 % (PROMIS-29 V2.0 scales), and 64 % (PROMIS-29 V2.0 items) of the variance in the HUI-3 preference score. Linear equated scores were similar to observed scores, although differences tended to be larger for older study participants. HUI-3 preference scores can be estimated from the PROMIS(®) global health items or PROMIS-29 V2.0. The estimated HUI-3 scores from the PROMIS(®) health measures can be used for economic applications and as a measure of overall HR-QOL in research.

Computing 3-D steady supersonic flow via a new Lagrangian approach

NASA Technical Reports Server (NTRS)

Loh, C. Y.; Liou, M.-S.

1993-01-01

The new Lagrangian method introduced by Loh and Hui (1990) is extended for 3-D steady supersonic flow computation. Details of the conservation form, the implementation of the local Riemann solver, and the Godunov and the high resolution TVD schemes are presented. The new approach is robust yet accurate, capable of handling complicated geometry and reactions between discontinuous waves. It keeps all the advantages claimed in the 2-D method of Loh and Hui, e.g., crisp resolution for a slip surface (contact discontinuity) and automatic grid generation along the stream.

Bilateral Vestibular Deficiency: Quality of Life and Economic Implications.

PubMed

Sun, Daniel Q; Ward, Bryan K; Semenov, Yevgeniy R; Carey, John P; Della Santina, Charles C

2014-06-01

Bilateral vestibular deficiency (BVD) causes chronic imbalance and unsteady vision and greatly increases the risk of falls; however, its effects on quality of life and economic impact are not well defined. To quantify disease-specific and health-related quality of life, health care utilization, and economic impact on individuals with BVD in comparison with those with unilateral vestibular deficiency (UVD). Cross-sectional survey study of patients with BVD or UVD and healthy controls at an academic medical center. Vestibular dysfunction was diagnosed by means of caloric nystagmography. Survey questionnaire. Health status was measured using the Dizziness Handicap Index (DHI) and Health Utility Index Mark 3 (HUI3). Economic burden was estimated using participant responses to questions on disease-specific health care utilization and lost productivity. Fifteen patients with BVD, 22 with UVD, and 23 healthy controls participated. In comparison with patients with UVD and controls, patients with BVD had significantly worse DHI (P < .001) and HUI3 scores. Statistically significant between-group differences were observed for overall HUI3 score (P < .001) and for specific attributes including vision, hearing, ambulation, emotion, and pain (P < .001 for all). Generalized linear model analysis of clinical variables associated with HUI3 scores after adjustment for other variables (including sex, race, education, age, and frequency of dizziness-related outpatient clinic visits) showed that the presence of UVD (P < .001) or BVD (P < .001), increased dizziness-related emergency room visits (P = .002), and increased dizziness-related missed work days (P < .001) were independently associated with worse HUI3 scores. Patients with BVD and UVD incurred estimated mean (range) annual economic burdens of $13,019 ($0-$48,830) and $3531 ($0-$48,442) per patient, respectively. Bilateral vestibular deficiency significantly decreases quality of life and imposes

76 FR 25690 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

.... Lanuzga, Vice President, Application Type: Business Structure Change. Embarque Bandera Shipping, Inc. (NVO... Road, Suite 222, Diamond Bar, CA 91765, Officer: Rachel Zhu, President, (Qualifying Individual...

Neural substrates of self-referential processing in Chinese Buddhists

PubMed Central

Gu, Xiaosi; Mao, Lihua; Ge, Jianqiao; Wang, Gang; Ma, Yina

2010-01-01

Our recent work showed that self-trait judgment is associated with increased activity in the ventral medial prefrontal cortex (VMPFC) in non-religious Chinese, but in the dorsal medial prefrontal cortex (DMPFC) in Chinese Christians. The current work further investigated neural substrates of self-referential processing in Chinese Buddhists. Using functional magnetic resonance imaging, we scanned 14 Chinese Buddhists, while they conducted trait judgments of the self, Zhu Rongji (the former Chinese premier), Sakyamuni (the Buddhist leader) and Jesus (the Christian leader). We found that, relative to Zhu Rongji judgment, self-judgment in Buddhist participants failed to generate increased activation in the VMPFC but induced increased activations in the DMPFC/rostral anterior cingulate cortex, midcingulate and the left frontal/insular cortex. Self-judgment was also associated with decreased functional connectivity between the DMPFC and posterior parietal cortex compared with Zhu Rongji judgment. The results suggest that Buddhist doctrine of No-self results in weakened neural coding of stimulus self-relatedness in the VMPFC, but enhanced evaluative processes of self-referential stimuli in the DMPFC. Moreover, self-referential processing in Buddhists is characterized by monitoring the conflict between the doctrine of No-self and self-focus thinking during self-trait judgment. PMID:19620181

A revision of Eastern Palaearctic Anthobium Leach, 1819 (Coleoptera: Staphylinidae: Omaliinae: Anthophagini). I. Gracilipalpe, morchella and nigrum groups.

PubMed

Shavrin, Alexey V; Smetana, Aleš

2017-12-15

Three new species-groups are established for eastern Palaearctic species of the genus Anthobium Leach, 1819: Gracilipalpe-group containing A. gracilipalpe (Champion, 1920) (Uttaranchal, Nepal), A. daliense sp.n. (China: Yunnan, Diancang Shan) and A. nivale sp.n. (China: Yunnan, Gaoligong Shan). Morchella-group containing A. morchella sp.n. (China: Yunnan, Baima Shan), A. hydraenoides sp.n. (China: Yunnan, Meili Xue Shan) and A. puetzi sp.n. (China: Sichuan, Daxue Shan, Qionglai Shan). Nigrum-Group containing A. nigrum (Cameron, 1924) (Himalaya), A. anishchenkoi sp.n. (China: Gansu, Dalijia Shan), A. conjunctum sp.n. (China: Yunnan, Diancang Shan), A. densepunctatum sp.n. (China: Yunnan, Meili Xue Shan) and A. ivani sp.n. (Nepal: Bagmati; Bhutan). The species groups are defined, briefly discussed and a key to the species included in each group is given. Lectotypes are designated for Eudeliphrum gracilipalpe Champion, 1920 and Lathrimaeum nigrum Cameron, 1924. Species in each species-group are described/redescribed, illustrated and their geographical distribution is mapped. Members of the genus Anthobium are recorded for the first time from China and Bhutan, and Anthobium gracilipalpe is recorded for the first time from Nepal.

Three-dimensional rotating flow of MHD single wall carbon nanotubes over a stretching sheet in presence of thermal radiation

NASA Astrophysics Data System (ADS)

Nasir, Saleem; Islam, Saeed; Gul, Taza; Shah, Zahir; Khan, Muhammad Altaf; Khan, Waris; Khan, Aurang Zeb; Khan, Saima

2018-05-01

In this article the modeling and computations are exposed to introduce the new idea of MHD three-dimensional rotating flow of nanofluid through a stretching sheet. Single wall carbon nanotubes (SWCNTs) are utilized as a nano-sized materials while water is used as a base liquid. Single-wall carbon nanotubes (SWNTs) parade sole assets due to their rare structure. Such structure has significant optical and electronics features, wonderful strength and elasticity, and high thermal and chemical permanence. The heat exchange phenomena are deliberated subject to thermal radiation and moreover the impact of nanoparticles Brownian motion and thermophoresis are involved in the present investigation. For the nanofluid transport mechanism, we implemented the Xue model (Xue, Phys B Condens Matter 368:302-307, 2005). The governing nonlinear formulation based upon the law of conservation of mass, quantity of motion, thermal field and nanoparticles concentrations is first modeled and then solved by homotopy analysis method (HAM). Moreover, the graphical result has been exposed to investigate that in what manner the velocities, heat and nanomaterial concentration distributions effected through influential parameters. The mathematical facts of skin friction, Nusselt number and Sherwood number are presented through numerical data for SWCNTs.

JPRS Report, Arms Control

DTIC Science & Technology

1989-11-13

manufacturing or using beam facilities. Radiation signs and necessary protection security interlocking mechanisms, alarm systems, or signals must be...JPRS-TAC-89-037 13 NOVEMBER 1989 JPRS tit Arms Control 715 159 REPRODUCED BY US DEPARTMENT OF COMMERCE NATIONAL TECHNICAL INFORMATION SERVICE...Xue Ren; J1EFANGJUN BAO 20 Oct] 4 Li Peng Signs Radiation Protection Decree [XINHUA 1 Nov] 5 Nuclear Technology Applied to Nonmilitary Use

China-U.S. Relations: Current Issues and Implications for U.S. Policy

DTIC Science & Technology

2009-11-20

would ease restrictions on foreign investments in the culture industry, to include film , publishing, entertainment, online games, and multi-media...President Obama did raise human rights issues in his discussions, in particular the case of American geologist Xue Feng who had been detained several...decision represents a departure from the previous administration of President George W. Bush, which denied import relief in six previous cases of petitions

A Data Assimilation System For Operational Weather Forecast In Galicia Region (nw Spain)

NASA Astrophysics Data System (ADS)

Balseiro, C. F.; Souto, M. J.; Pérez-Muñuzuri, V.; Brewster, K.; Xue, M.

Regional weather forecast models, such as the Advanced Regional Prediction System (ARPS), over complex environments with varying local influences require an accurate meteorological analysis that should include all local meteorological measurements available. In this work, the ARPS Data Analysis System (ADAS) (Xue et al. 2001) is applied as a three-dimensional weather analysis tool to include surface station and rawinsonde data with the NCEP AVN forecasts as the analysis background. Currently in ADAS, a set of five meteorological variables are considered during the analysis: horizontal grid-relative wind components, pressure, potential temperature and spe- cific humidity. The analysis is used for high resolution numerical weather prediction for the Galicia region. The analysis method used in ADAS is based on the successive corrective scheme of Bratseth (1986), which asymptotically approaches the result of a statistical (optimal) interpolation, but at lower computational cost. As in the optimal interpolation scheme, the Bratseth interpolation method can take into account the rel- ative error between background and observational data, therefore they are relatively insensitive to large variations in data density and can integrate data of mixed accuracy. This method can be applied economically in an operational setting, providing signifi- cant improvement over the background model forecast as well as any analysis without high-resolution local observations. A one-way nesting is applied for weather forecast in Galicia region, and the use of this assimilation system in both domains shows better results not only in initial conditions but also in all forecast periods. Bratseth, A.M. (1986): "Statistical interpolation by means of successive corrections." Tellus, 38A, 439-447. Souto, M. J., Balseiro, C. F., Pérez-Muñuzuri, V., Xue, M. Brewster, K., (2001): "Im- pact of cloud analysis on numerical weather prediction in the galician region of Spain". Submitted to Journal of

A comparison of doctors', parents' and children's reports of health states and health-related quality of life in children with chronic conditions.

PubMed

Morrow, A M; Hayen, A; Quine, S; Scheinberg, A; Craig, J C

2012-03-01

Health-related quality of life is an important outcome. Self-report is the gold standard, but in the paediatric setting we often rely on proxy reporting. Our understanding of the differences between self- and proxy reports and the factors that influence them is limited. These differences can impact on treatment choices and the patient-doctor relationship. To evaluate differences between children's, parents' and doctors' perceptions of health states and health-related quality of life in children with chronic illness and explore factors which explain these differences. Consecutive families attending eligible clinics at a tertiary paediatric centre were invited to complete the Health Utilities Index (HUI) 23 questionnaire. Percentage agreement and kappas were calculated as a measure of the agreement between pairs. Chi-squared tests or Fisher's exact test, if appropriate, were performed to determine if there was an association between level of agreement and participant variables. Data were collected for 130 parent-doctor pairs, 59 child-parent pairs and 59 child-doctor pairs. Overall health-related quality of life scores did not differ between responders, but there was poorer agreement for subjective domains. Doctor-child agreement was lower than parent-child agreement. Children with a diagnosis of cerebral palsy or chronic neurological condition were more likely to have lower inter-rater agreement for both subjective and objective domains. On the HUI2, agreement was lower for parent-child pairs when the father was the respondent. For child-doctor pairs, an increased frequency of patient-doctor visits and doctors' seniority were predictors of poorer agreement on the HUI3 and HUI2 respectively. We identified factors associated with level of agreement for self- and proxy reporting on the HUI23. Parent-child agreement was higher than doctor-child agreement. Patients with significant pain or emotional distress and patients with a diagnosis of severe cerebral palsy or

Effects of sedentary occupations on type 2 diabetes and hypertension in different ethnic groups in North West China.

PubMed

Gao, Ying; Xie, Xiang; Wang, Shu-Xia; Li, Hui; Tang, Han-Zhou; Zhang, Jing; Yao, Hua

2017-07-01

This study investigated the effects of sedentary occupations on type 2 diabetes and hypertension in different ethnic groups in North West China. All subjects were civil servants who received health examinations in the First Affiliated Hospital of Xinjiang Medical University from October 2010 to March 2014. A total of 46,612 participants (39,120 Han, 4148 Uygur, 2098 Hui, 877 Kazak and 369 other ethnicities) completed the examination. Overall, 16.4% of the Han, 14.4% of the Uygur, 15.9% of the Hui, 20.6% of the Kazak and 16.0% of other ethnicities had hypertension. Diabetes was found in 7.6% of the Han, 8.5% of the Uygur, 9.2% of the Hui, 7.4% of the Kazak, and 3.3% of other ethnicities. There was a significant difference between men and women in the prevalence of diabetes (4.3% in women vs 9.7% in men, p < 0.001) and hypertension (9.7% in women vs 21.0% in men, p < 0.001). Our results indicate that both diabetes and hypertension are highly prevalent in individuals with sedentary occupations.

China Report, Political, Sociological and Military Affairs, No. 412.

DTIC Science & Technology

1983-04-18

b - Cadre Support for Reform Encouraged (Xue Song ; QUNZHONG, 5 Jan 83) 66 Need to Understand, Implement New Constitution Stressed (LIAONING...Hong Peilin [3163 3099 7207] as Honorary President, Wei Yongyi [7279 3057 5030] as President"] [Text] The inaugural meeting of the Jiangsu Law...of directors of the society and chose Hong Peilin as its honorary president. At the first plenary session of its first board meeting, Wei Yongyi

Transparent and Stretchable High-Performance Supercapacitors Based on Wrinkled Graphene Electrodes

DTIC Science & Technology

2013-12-18

High-Performance Supercapacitors Based onWrinkledGraphene Electrodes Tao Chen,† Yuhua Xue,† Ajit K. Roy,‡ and Liming Dai†,* †Center of Advanced Science...electrodes and the associated supercapacitor cells cannot be both trans- parent and stretchable.1318 It is highly desirable to integrate the...devices (e.g., supercapacitors ) because most of the exist- ing electrodes are neither stretchable nor transparent (e.g., metal electrodes) with some of them

Hormonal Involvement in Breast Cancer Gene Amplification

DTIC Science & Technology

2008-10-01

and transcriptome. Genome Res.16: 394-404. Zhu W. and Dutta A. (2006). Activation of Fanconi anemia pathway in cells with re- replicated DNA. Cell Cycle 5: 2306-2309. APPENDICES None SUPPORTING DATA None

Corrigendum to "Stem breakage of salt marsh vegetation under wave forcing: A field and model study" [Estuar. Coast Shelf Sci. 200 (2018) 41-58

NASA Astrophysics Data System (ADS)

Vuik, Vincent; Suh Heo, Hannah Y.; Zhu, Zhenchang; Borsje, Bas W.; Jonkman, Sebastiaan N.

2018-03-01

The authors regret that the correct affiliation of co-author Zhenchang Zhu should be 'Department of Estuarine and Delta Systems, Royal Netherlands Institute for Sea Research and Utrecht University, 4400AC, Yerseke, The Netherlands'.

Living with endometriosis

MedlinePlus

... breathing Visualization Biofeedback Yoga Some women find that acupuncture helps ease painful periods. Some studies show it ... Zhu X, Li X, Lu ZY, Song J. Acupuncture for dysmenorrhoea. Cochrane Database Syst Rev . 2016;4: ...

Response to Bile Salts in Clinical Strains of Acinetobacter baumannii Lacking the AdeABC Efflux Pump: Virulence Associated with Quorum Sensing

PubMed Central

López, Maria; Blasco, Lucia; Gato, Eva; Perez, Astrid; Fernández-Garcia, Laura; Martínez-Martinez, Luis; Fernández-Cuenca, Felipe; Rodríguez-Baño, Jesús; Pascual, Alvaro; Bou, German; Tomás, Maria

2017-01-01

Introduction: Acinetobacter baumannii is an opportunistic nosocomial pathogen associated with multiple infections. This pathogen usually colonizes (first stage of microbial infection) host tissues that are in contact with the external environment. As one of the sites of entry in human hosts is the gastrointestinal tract, the pathogen must be capable of tolerating bile salts. However, studies analyzing the molecular characteristics involved in the response to bile salts in clinical strains of A. baumannii are scarce. Material and Methods: Microbiological and transcriptional studies (arrays and RT-PCR) in the response to bile salts were carried out in isogenic (A. baumanni ΔadeB ATCC 17978 and A. baumannii ΔadeL ATCC 17978) and clinical strains from clone ST79/PFGE-HUI-1 which is characterized by lacking the AdeABC efflux pump and by overexpression the AdeFGH efflux pump. Results and Discussion: In presence of bile salts, in addition to the glutamate/aspartate transporter were found overexpressed in A. baumannii ΔadeB ATCC 17978, the virulence factors (surface motility, biofilm, and Type VI Secretion System) which are associated with activation of the Quorum Sensing system. Overexpression of these factors was confirmed in clinical strains of clone ST79/PFGE-HUI-1. Conclusions: This the first study about the adaptive response to bile salts investigating the molecular and microbiological characteristics in response to bile salts of an isogenic model of A. baumannii ATCC 17978 and clinical isolates of A. baumannii (clinical strains of ST79/PFGE-HUI-1) lacking the main RND efflux pump (AdeABC). Clinical isolates of A. baumannii lacking the AdeABC efflux pump (clone ST79/PFGE-HUI-1) displayed a new clinical profile (increased invasiveness) possibly associated with the response to stress conditions (such as the presence of bile salts). PMID:28536672

Bibliography of Literature on China’s Glaciers and Permafrost. Part I. 1938-1979.

DTIC Science & Technology

1982-09-01

The Quaternary Period Glaciers of China. Kexue Chubanshe, 1975. Li Chengsan and Guo Lingzhi : Glacier topography at Kangding-bianfu. Dizhi Lunping...Vol. 4, No. 1, 1939. Li Chengsan and Gao Yongyuan: Glacier topography in the Daba Shan at Guangyuan. Dili, Vol. 2, Nos. 1-2, 1942. Guo Lingzhi ...Mountains region. Zhongguo Disiji Yanjiu, Vol. 1, No. 1, 1958. Guo Lingzhi and Xue Yuqun: A discussion of the relationship of the Fen River and the

BATTLE (Biomarker-based Approach of Targeted Therapy for Lung Cancer Elimination)

DTIC Science & Technology

2012-04-01

Wistuba,Ignacio Ivan Woods ,Denise M Wu,Huakang Xue,Yuwen Yang,Bijun Yin,Ming Zhang,Guangcheng Zhang,Li Army...Oncol. 2009; 27: 271–8. 127 Ishii Y, Rex M, Scotting PJ et al. Region-specific expression of chicken Sox2 in the developing gut and lung epithelium... Wood ER, Shewchuk L, Hassel A, et al. Discovery of an in- hibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency

Mass Spectrometry to Identify New Biomarkers of Nerve Agent Exposure

DTIC Science & Technology

2009-04-01

covalent bond with the active site serine in the consensus sequence GXSXG of esterases and proteases. However, the site of attachment to proteins...that have no active site serine has only recently been recognized as tyrosine. In last year’s report we provided mass spectrometry evidence that...PMID: 18502412 Lockridge O, Xue W, Gaydess A, Grigoryan H, Ding SJ, Schopfer LM, Hinrichs SH, Masson P. Pseudo- esterase activity of human albumin

Minimum Error Bounded Efficient L1 Tracker with Occlusion Detection (PREPRINT)

DTIC Science & Technology

2011-01-01

Minimum Error Bounded Efficient `1 Tracker with Occlusion Detection Xue Mei\\ ∗ Haibin Ling† Yi Wu†[ Erik Blasch‡ Li Bai] \\Assembly Test Technology...proposed BPR-L1 tracker is tested on several challenging benchmark sequences involving chal- lenges such as occlusion and illumination changes. In all...point method de - pends on the value of the regularization parameter λ. In the experiments, we found that the total number of PCG is a few hundred. The

Population genetic study of 34 X-Chromosome markers in 5 main ethnic groups of China.

PubMed

Zhang, Suhua; Bian, Yingnan; Li, Li; Sun, Kuan; Wang, Zheng; Zhao, Qi; Zha, Lagabaiyila; Cai, Jifeng; Gao, Yuzhen; Ji, Chaoneng; Li, Chengtao

2015-12-04

As a multi-ethnic country, China has some indigenous population groups which vary in culture and social customs, perhaps as a result of geographic isolation and different traditions. However, upon close interactions and intermarriage, admixture of different gene pools among these ethnic groups may occur. In order to gain more insight on the genetic background of X-Chromosome from these ethnic groups, a set of X-markers (18 X-STRs and 16 X-Indels) was genotyped in 5 main ethnic groups of China (HAN, HUI, Uygur, Mongolian, Tibetan). Twenty-three private alleles were detected in HAN, Uygur, Tibetan and Mongolian. Significant differences (p < 0.0001) were all observed for the 3 parameters of heterozygosity (Ho, He and UHe) among the 5 ethnic groups. Highest values of Nei genetic distance were always observed at HUI-Uygur pairwise when analyzed with X-STRs or X-Indels separately and combined. Phylogenetic tree and PCA analyses revealed a clear pattern of population differentiation of HUI and Uygur. However, the HAN, Tibetan and Mongolian ethnic groups were closely clustered. Eighteen X-Indels exhibited in general congruent phylogenetic signal and similar cluster among the 5 ethnic groups compared with 16 X-STRs. Aforementioned results proved the genetic polymorphism and potential of the 34 X-markers in the 5 ethnic groups.

[Variation of CAG repeats in coding region of ATXN2 gene in different ethnic groups].

PubMed

Chen, Xiao-Chen; Sun, Hao; Mi, Dong-Qing; Huang, Xiao-Qin; Lin, Ke-Qin; Yi, Wen; Yu, Liang; Shi, Lei; Shi, Li; Yang, Zhao-Qing; Chu, Jia-You

2011-04-01

Toinvestigate CAG repeats variation of ATXN2 gene coding region in six ethnic groups that live in comparatively different environments, to evaluate whether these variations are under positive selection, and to find factors driving selection effects, 291 unrelated healthy individuals were collected from six ethnic groups and their STR geneotyping was performed. The frequencies of alleles and genotypes were counted and thereby Slatkin's linearized Fst values were calculated. The UPGMA tree against this gene was constructed. The MDS analysis among these groups was carried out as well. The results from the linearized Fst values indicated that there were significant evolutionary differences of the STR in ATXN2 gene between Hui and Yi groups, but not among the other 4 groups. Further analysis was performed by combining our data with published data obtained from other groups. These results indicated that there were significant differences between Japanese and other groups including Hui, Hani, Yunnan Mongolian, and Inner Mongolian. Both Hui and Mongolian from Inner Mongolia were significantly different from Han. In conclusion, the six ethnic groups had their own distribution characterizations of allelic frequencies of ATXN2 STR, and the potential cause of frequency changes in rare alleles could be the consequence of positive selection.

NREL Research Pinpoints Promise of Polycrystalline Perovskites | News |

Science.gov Websites

Beard, David Moore and Elisa Miller are co-authors of a new paper in Nature Energy about perovskites , Yong Yan, Elisa M. Miller, and Kai Zhu. Beard said the research determined surface recombination

Do generic utility measures capture what is important to the quality of life of people with multiple sclerosis?

PubMed

Kuspinar, Ayse; Mayo, Nancy E

2013-04-25

The three most widely used utility measures are the Health Utilities Index Mark 2 and 3 (HUI2 and HUI3), the EuroQol-5D (EQ-5D) and the Short-Form-6D (SF-6D). In line with guidelines for economic evaluation from agencies such as the National Institute for Health and Clinical Excellence (NICE) and the Canadian Agency for Drugs and Technologies in Health (CADTH), these measures are currently being used to evaluate the cost-effectiveness of different interventions in MS. However, the challenge of using such measures in people with a specific health condition, such as MS, is that they may not capture all of the domains that are impacted upon by the condition. If important domains are missing from the generic measures, the value derived will be higher than the real impact creating invalid comparisons across interventions and populations. Therefore, the objective of this study is to estimate the extent to which generic utility measures capture important domains that are affected by MS. The available study population consisted of men and women who had been registered after 1994 in three participating MS clinics in Greater Montreal, Quebec, Canada. Subjects were first interviewed on an individualized measure of quality of life (QOL) called the Patient Generated Index (PGI). The domains identified with the PGI were then classified and grouped together using the World Health Organization's International Classification of Functioning, Disability and Health (ICF), and mapped onto the HUI2, HUI3, EQ-5D and SF-6D. A total of 185 persons with MS were interviewed on the PGI. The sample was relatively young (mean age 43) and predominantly female. Both men and women had mild disability with a median Expanded Disability Status Scale (EDSS) score of 2. The top 10 domains that patients identified to be the most affected by their MS were, work (62%), fatigue (48%), sports (39%), social life (28%), relationships (23%), walking/mobility (22%), cognition (21%), balance (14%), housework (12

Do generic utility measures capture what is important to the quality of life of people with multiple sclerosis?

PubMed Central

2013-01-01

Purpose The three most widely used utility measures are the Health Utilities Index Mark 2 and 3 (HUI2 and HUI3), the EuroQol-5D (EQ-5D) and the Short-Form-6D (SF-6D). In line with guidelines for economic evaluation from agencies such as the National Institute for Health and Clinical Excellence (NICE) and the Canadian Agency for Drugs and Technologies in Health (CADTH), these measures are currently being used to evaluate the cost-effectiveness of different interventions in MS. However, the challenge of using such measures in people with a specific health condition, such as MS, is that they may not capture all of the domains that are impacted upon by the condition. If important domains are missing from the generic measures, the value derived will be higher than the real impact creating invalid comparisons across interventions and populations. Therefore, the objective of this study is to estimate the extent to which generic utility measures capture important domains that are affected by MS. Methods The available study population consisted of men and women who had been registered after 1994 in three participating MS clinics in Greater Montreal, Quebec, Canada. Subjects were first interviewed on an individualized measure of quality of life (QOL) called the Patient Generated Index (PGI). The domains identified with the PGI were then classified and grouped together using the World Health Organization’s International Classification of Functioning, Disability and Health (ICF), and mapped onto the HUI2, HUI3, EQ-5D and SF-6D. Results A total of 185 persons with MS were interviewed on the PGI. The sample was relatively young (mean age 43) and predominantly female. Both men and women had mild disability with a median Expanded Disability Status Scale (EDSS) score of 2. The top 10 domains that patients identified to be the most affected by their MS were, work (62%), fatigue (48%), sports (39%), social life (28%), relationships (23%), walking/mobility (22%), cognition (21

Proteomic Analysis to Identify Functional Molecules in Drug Resistance Caused by E-Cadherin Knockdown in 3D-Cultured Colorectal Cancer Models

DTIC Science & Technology

2013-09-01

REFERENCES (1) Harsha, H. C.; Pandey, A. Phosphoproteomics in cancer. Mol. Oncol. 2010, 4 (6), 482−95. (2) Iliuk , A.; Liu, X. S.; Xue, L.; Liu, X...based proteomics and peptidomics for biomarker discovery in neurodegenerative diseases. Int. J. Clin. Exp. Pathol. 2009, 2 (2), 132−48. (4) Iliuk , A...phosphoproteins by immobilized metal (Fe3+) affinity chromatography. Anal. Biochem. 1986, 154 (1), 250−4. (6) Iliuk , A. B.; Martin, V. A.; Alicie, B. M

Graphene Oxide Nanoribbon as Hole Extraction Layer to Enhance Efficiency and Stability of Polymer Solar Cells

DTIC Science & Technology

2013-01-01

Oxide Nanoribbon as Hole Extraction Layer to Enhance Effi ciency and Stability of Polymer Solar Cells Jun Liu , Gi-Hwan Kim , Yuhua Xue , Jin...circumvented by oxidizing graphene with acids (e.g., H 2 SO 4 /KMnO 4 ) to produce graphene oxide (GO) with oxygen-containing groups (e.g., –COOH, –OH...introducing the oxygen-rich groups around a graphene nanoribbon, the resultant graphene oxide nanoribbon (GOR) should show a synergistic effect to have

Ferroelectric large polarons

NASA Astrophysics Data System (ADS)

Miyata, Kiyoshi; Zhu, X.-Y.

2018-05-01

Kiyoshi Miyata and X.-Y. Zhu analyse the ferroelectric-like dielectric response of lead halide perovskites in the terahertz region and discuss the potential role of polar nanodomains in accounting for the defect tolerance and low recombination rates of these materials.

Using Phage Lytic Enzymes to Destroy Pathogenic and BW Bacteria

DTIC Science & Technology

2005-07-14

against antibiotic resistant Enterococcus faecalis and Enterococcus faecium . J Bacteriol. 186:4808-12. Cheng, Q., D. Nelson, S. Zhu, and V.A...Lysins from Enterococcus faecalis RU-654 3. Fischetti, Vincent A. Schuch, Raymond Lytic Enzymes and spore surface antigens for detection and

Improving estimates of real-time traffic speeds during weather for winter maintenance performance measurements.

DOT National Transportation Integrated Search

2017-04-01

Vianey Leos Barajas (orcid.org/0000-0001-8016-773X), Zhonglei Wang (orcid.org/0000-0001-6712-0750), Mark Kaiser (orcid.org/0000-0003-0449-0388), and Zhengyuan Zhu (orcid.org/0000-0002-2266-0646) : This report describes two related projects, the secon...

Population genetic study of 34 X-Chromosome markers in 5 main ethnic groups of China

PubMed Central

Zhang, Suhua; Bian, Yingnan; Li, Li; Sun, Kuan; wang, Zheng; Zhao, Qi; Zha, Lagabaiyila; Cai, Jifeng; Gao, Yuzhen; Ji, Chaoneng; Li, Chengtao

2015-01-01

As a multi-ethnic country, China has some indigenous population groups which vary in culture and social customs, perhaps as a result of geographic isolation and different traditions. However, upon close interactions and intermarriage, admixture of different gene pools among these ethnic groups may occur. In order to gain more insight on the genetic background of X-Chromosome from these ethnic groups, a set of X-markers (18 X-STRs and 16 X-Indels) was genotyped in 5 main ethnic groups of China (HAN, HUI, Uygur, Mongolian, Tibetan). Twenty-three private alleles were detected in HAN, Uygur, Tibetan and Mongolian. Significant differences (p < 0.0001) were all observed for the 3 parameters of heterozygosity (Ho, He and UHe) among the 5 ethnic groups. Highest values of Nei genetic distance were always observed at HUI-Uygur pairwise when analyzed with X-STRs or X-Indels separately and combined. Phylogenetic tree and PCA analyses revealed a clear pattern of population differentiation of HUI and Uygur. However, the HAN, Tibetan and Mongolian ethnic groups were closely clustered. Eighteen X-Indels exhibited in general congruent phylogenetic signal and similar cluster among the 5 ethnic groups compared with 16 X-STRs. Aforementioned results proved the genetic polymorphism and potential of the 34 X-markers in the 5 ethnic groups. PMID:26634331

Five preference-based indexes in cataract and heart failure patients were not equally responsive to change.

PubMed

Kaplan, Robert M; Tally, Steven; Hays, Ron D; Feeny, David; Ganiats, Theodore G; Palta, Mari; Fryback, Dennis G

2011-05-01

To compare the responsiveness to clinical change of five widely used preference-based health-related quality-of-life indexes in two longitudinal cohorts. Five generic instruments were simultaneously administered to 376 adults undergoing cataract surgery and 160 adults in heart failure management programs. Patients were assessed at baseline and reevaluated after 1 and 6 months. The measures were the Short Form (SF)-6D (based on responses scored from SF-36v2), Self-Administered Quality of Well-being Scale (QWB-SA), the EuroQol-5D developed by the EuroQol Group, the Health Utilities Indexes Mark 2 (HUI2) and Mark 3 (HUI3). Cataract patients completed the National Eye Institute Visual Functioning Questionnaire-25, and heart failure patients completed the Minnesota Living with Heart Failure Questionnaire. Responsiveness was estimated by the standardized response mean. For cataract patients, mean changes between baseline and 1-month follow-up for the generic indices ranged from 0.00 (SF-6D) to 0.052 (HUI3) and were statistically significant for all indexes except the SF-6D. For heart failure patients, only the SF-6D showed significant change from baseline to 1 month, whereas only the QWB-SA change was significant between 1 and 6 months. Preference-based methods for measuring health outcomes are not equally responsive to change. Copyright © 2011 Elsevier Inc. All rights reserved.

Multiattribute health utility scoring for the computerized adaptive measure CAT-5D-QOL was developed and validated.

PubMed

Kopec, Jacek A; Sayre, Eric C; Rogers, Pamela; Davis, Aileen M; Badley, Elizabeth M; Anis, Aslam H; Abrahamowicz, Michal; Russell, Lara; Rahman, Md Mushfiqur; Esdaile, John M

2015-10-01

The CAT-5D-QOL is a previously reported item response theory (IRT)-based computerized adaptive tool to measure five domains (attributes) of health-related quality of life. The objective of this study was to develop and validate a multiattribute health utility (MAHU) scoring method for this instrument. The MAHU scoring system was developed in two stages. In phase I, we obtained standard gamble (SG) utilities for 75 hypothetical health states in which only one domain varied (15 states per domain). In phase II, we obtained SG utilities for 256 multiattribute states. We fit a multiplicative regression model to predict SG utilities from the five IRT domain scores. The prediction model was constrained using data from phase I. We validated MAHU scores by comparing them with the Health Utilities Index Mark 3 (HUI3) and directly measured utilities and by assessing between-group discrimination. MAHU scores have a theoretical range from -0.842 to 1. In the validation study, the scores were, on average, higher than HUI3 utilities and lower than directly measured SG utilities. MAHU scores correlated strongly with the HUI3 (Spearman ρ = 0.78) and discriminated well between groups expected to differ in health status. Results reported here provide initial evidence supporting the validity of the MAHU scoring system for the CAT-5D-QOL. Copyright © 2015 Elsevier Inc. All rights reserved.

Integrated Modeling of Polymer Composites Under High Energy Laser Irradiation

DTIC Science & Technology

2015-10-30

L. Bougher, A. Weathers, Y. Cai, K. Bi, M. T. Pettes, S. A. McMenamin, W. Lv, D. P. Resler, T. R. Gattuso, et al . 2014. "High Thermal Conductivity...146. 35. Huxtable, S. T., D. G. Cahill, S. Shenogin, L. Xue, R. Ozisik, P. Barone, M. Usrey, M. S. Strano, G. Siddons, M. Shim, et al . 2003...temperature and spectra becomes more complicated. Recently Liu et al . observed that, when held at elevated temperatures for extended times, AuNRs in poly

76 FR 53409 - Wooden Bedroom Furniture From the People's Republic of China: Corrected Notice of Court Decision...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

... Enterprises Ltd., or Well Earth International Ltd.; Dongguan Kin Feng Furniture Co., Ltd.; Dongguan... (Hui-Yang) Co., Ltd., or Sun Fung Wooden Factory, or Sun Fung Co., or Shin Feng Furniture Co., Ltd., or...

The Development and Testing of a Tool for Analysis of Computer-Mediated Conferencing Transcripts.

ERIC Educational Resources Information Center

Fahy, Patrick J.; Crawford, Gail; Ally, Mohamed; Cookson, Peter; Keller, Verna; Prosser, Frank

2000-01-01

The Zhu model for analyzing computer mediated communications was further developed by an Athabasca University (Alberta) distance education research team based on ease of use, reliability, validity, theoretical support, and cross-discipline utility. Five classification categories of the new model are vertical questioning, horizontal questioning,…

STUDY OF ULTRAFINE PARTICLES NEAR A MAJOR HIGHWAY WITH HEAVY-DUTY DIESEL TRAFFIC. (R827352C011)

EPA Science Inventory

Motor vehicle emissions usually constitute the most significant source of ultrafine particles (diameter <0.1 m) in an urban environment. Zhu et al. (J. Air Waste Manage. As...

An Efficient and Secure Arbitrary N-Party Quantum Key Agreement Protocol Using Bell States

NASA Astrophysics Data System (ADS)

Liu, Wen-Jie; Xu, Yong; Yang, Ching-Nung; Gao, Pei-Pei; Yu, Wen-Bin

2018-01-01

Two quantum key agreement protocols using Bell states and Bell measurement were recently proposed by Shukla et al. (Quantum Inf. Process. 13(11), 2391-2405, 2014). However, Zhu et al. pointed out that there are some security flaws and proposed an improved version (Quantum Inf. Process. 14(11), 4245-4254, 2015). In this study, we will show Zhu et al.'s improvement still exists some security problems, and its efficiency is not high enough. For solving these problems, we utilize four Pauli operations { I, Z, X, Y} to encode two bits instead of the original two operations { I, X} to encode one bit, and then propose an efficient and secure arbitrary N-party quantum key agreement protocol. In the protocol, the channel checking with decoy single photons is introduced to avoid the eavesdropper's flip attack, and a post-measurement mechanism is used to prevent against the collusion attack. The security analysis shows the present protocol can guarantee the correctness, security, privacy and fairness of quantum key agreement.

PREFACE International Symposium on Spintronic Devices and Commercialization 2010

NASA Astrophysics Data System (ADS)

Du, You-wei; Judy, Jack; Qian, Zhenghong; Wang, Jianping

2011-01-01

very successful indeed. We are also grateful to the Advisory Committee, the Conference Chairs, the Excutive Chairs, the Academic Committee, the Organization Committee and the Secretariat for their fruitful work. We would especially like to thank all the organizers listed below for their support in all aspects of the conference. We would like to express our thanks to all the authors for their time and genuine efforts, and to the reviewers for their fruitful comments during the preparation of this volume. ISSDC'2010 ORGANIZATION Advisory Committee Chialing Chien, USAJunhao Chu, ChinaBernard Dieny, FranceKoichiro Inomata, Japan Liangmo Mei, ChinaJohn Sivertsen, USAMingjing Tu, ChinaDingsheng Wang, China Zhanguo Wang, ChinaQikun Xue, ChinaWenshan Zhan, China Conference Chairs Jack Judy, USAYouwei Du, China Executive Chairs Zhenghong Qian, USAJianping Wang, USA Organization Committee ChairJiyan Luo, China Vice ChairsGuilin Duan, ChinaLingling Sun, ChinaBaogen Shen, China MembersTiecheng Lu, ChinaDa Ma, ChinaYe Tian, China Jinsong Xu, ChinaQiuling XuChangmao Yang, China Guanghua Yu, ChinaYi Yan, China Academic Committee ChairsZhenghong Qian, USAYongbing Xu, UK Vice ChairsSeongtae Bae, SingaporeYong Jiang, ChinaDexin Wang, USA Huaiwu Zhang, ChinaJianhua Zhao, China MembersJianwang Cai, ChinaXiangdong Chen, ChinaHaifeng Ding, China Chunhong Hou, USAGunther Baubock, USABin Hu, USA Jungchun Huang, TaiwanDexuan Huo, ChinaYoon H Jeong, Korea Chihuang Lai, TaiwanRunwei Li, ChinaWei Liu, China Jing Shi, USAYasushi Takemura, JapanMark Tondra, USA Shan X Wang, USADi Wu, ChinaDesheng Xue, China Minglang Yan, USAShishen Yan, ChinaXiaofei Yang, China Chun Yeol You, KoreaWei Zhao, ChinaShiming Zhou, China Jianguo Zhu, China Secretariat Secretary-generalChangmao Yang, China Vice Secretary-generalJunli Wang, ChinaJinsong Xu, ChinaYe Tian, China MembersRu Bai, ChinaHongliang Zhan, China ISSDC' 2010 Organizers Department of Science and Technology, CSIC, China SpinIC Inc., China Hangzhou

Androgen Receptor Splice Variants and Resistance to Taxane Chemotherapy

DTIC Science & Technology

2015-10-01

Cancer. 2004; 4:253–265. 7. Zhu ML, Horbinski CM, Garzotto M, Qian DZ, Beer TM, Kyprianou N. Tubulin-targeting chemotherapy impairs androgen receptor...article must therefore be hereby marked advertisement in accordance with 18 U.S.C. Section 1734 solely to indicate this fact. Received February 6

Three Dimensionally Interconnected Silicon Nanomembranes for Optical Phased Array (OPA) and Optical True Time Delay (TTD) Applications

DTIC Science & Technology

2012-06-01

Nanophotonic Waveguides," J. Lightwave Technol. 25 (1), 151-156 (2007). [7-4] Yongbo Tang, Zhechao Wang, Lech Wosinski, Urban Westergren, and Sailing...Waveguides," Photonics Journal, IEEE 3 (2), 203-208 (2011). [8-25] Zhechao Wang, Ning Zhu, Yongbo Tang, Lech Wosinski, Daoxin Dai, and Sailing He

Biomechanical and Biochemical Cellular Response Due to Shock Waves

DTIC Science & Technology

2008-12-01

112, 1183-1195. Yen, C.-F., 2008, US Army Reserach Laboratory. Zhong, P., I. Cioanta, F. H. Cocks, and G. M. Preminger, 1997: Inertial cavitation...2940-2950. Zhong, P., H. F. Lin, X. F. Xi, S. L. Zhu, and E. S. Bhogte, 1999: Shock wave-inertial microbubble interaction: Methodology

China's Higher Education Reform 1998-2003: A Summary

ERIC Educational Resources Information Center

Lixu, Li

2004-01-01

Profoundly important and unprecedented changes have taken place in China's higher education since 1998, when Zhu Rongji Administration (1998-2003) decided to carry out a new round of educational reform. These changes include some breakthroughs in macro administrative system reform, growth in the total amount of educational expenditure, the…

Response to Intervention: Is the Sky Falling?

ERIC Educational Resources Information Center

Dougherty Stahl, Katherine A.

2016-01-01

Response to Intervention (RTI) is a multiple tiered system of instructional interventions that may also serve to identify children with Specific Learning Disabilities (particularly in reading and spelling). This article summarizes the findings of Evaluation of Response to Intervention Practices for Elementary School Reading (Balu, Zhu, Doolittle,…

The genus Scaphidium Olivier in East China (Coleoptera, Staphylinidae, Scaphidiinae)

PubMed Central

Tang, Liang; Li, Li-Zhen; He, Wen-Jia

2014-01-01

Abstract A review of 21 species of Scaphidium Olivier from East China is presented, including 6 new species: S. jinmingi sp. n. (Zhejiang, Anhui, Chongqing), S. crypticum sp. n. (Zhejiang, Fujian, Jiangxi, Guangxi), S. varifasciatum sp. n. (Zhejiang, An’hui), S. robustum sp. n. (Fujian, Guizhou, Chongqing, Guangxi, Yunnan), S. connexum sp. n. (Zhejiang, Fujian, Guangxi), and S. bayibini sp. n. (An’hui). New province records for S. comes Löbl, S. grande Gestro, S. sauteri Miwa & Mitono, S. formosanum Pic, S. carinense Achard, S. sinense Pic, S. delatouchei Achard, S. biwenxuani He, Tang & Li, S. klapperichi Pic, S. stigmatinotum Löbl, S. wuyongxiangi He, Tang & Li, and S. direptum Tang & Li as well as some biological notes are reported. Habitus and diagnostic characters of all species are photographed and a key to Scaphidium species of East China is provided. PMID:24843266

[Study on baking processing technology of hui medicine Aconitum flavum].

PubMed

Fu, Xue-yan; Zhang, Bai-tong; Li, Ting-ting; Dong, Lin; Hao, Wen-jing; Yu, Liang

2013-12-01

To screen and optimize the processing technology of Aconitum flavum. The acute-toxicity, anti-inflammatory and analgesic experiments were used as indexes. Four processing methods, including decoction, streaming, baking and processing with Chebulae Fructus decoction, were compared to screen the optimum processing method for Aconitum flavum. The baking time was also optimized. The optimal baked technology was that 1-2 mm decoction pieces was baked at 105 degrees C for 3 hours. The baking method is proved to be the optimal processing method of Aconitum flavum. It is shown that this method is simple and stable.

Drift in Children's Categories: When Experienced Distributions Conflict with Prior Learning

ERIC Educational Resources Information Center

Kalish, Charles W.; Zhu, XiaoJin; Rogers, Timothy T.

2015-01-01

Psychological intuitions about natural category structure do not always correspond to the true structure of the world. The current study explores young children's responses to conflict between intuitive structure and authoritative feedback using a semi-supervised learning (Zhu et al., 2007) paradigm. In three experiments, 160 children between the…

Assessment of Nanobiotechnology-Targeted siRNA Designed to Inhibit NF-KappaB Classical and Alternative Signaling in Breast Tumor Macrophages

DTIC Science & Technology

2014-07-01

Venkataraman R, Crowder SW, Jung DK, Yu SS, Feaster TK, Giorgio TD, Hong CC, Baudenbacher FJ, Hatzopoulos AK and Sung HJ: Combinatorial Electrospun Matrices...Diabetic Complications, Journal of the American Society of Nephrology : JASN, 2009, 20, 2503-2512. 37. E. Y. Lin, J. G. Jones, P. Li, L. Zhu, K. D

Active-Vision Control Systems for Complex Adversarial 3-D Environments

DTIC Science & Technology

2009-03-01

Control Systems MURI Final Report 36 51. D. Nain, S. Haker , A. Bobick, A. Tannenbaum, "Multiscale 3D shape representation and segmentation using...Conference, August 2008. 99. L. Zhu, Y. Yang, S. Haker , and A. Tannenbaum, "An image morphing technique based on optimal mass preserving mapping," IEEE

Impact Of Obesity On Tamoxifen Chemoprevention In A Model Of Ductal Carcinoma In Situ

DTIC Science & Technology

2011-10-01

Antitumor effects of ursolic acid in a mouse model of postmenopausal breast cancer. Nutrition and Cancer 62(8):1074-86, 2010. Zheng Q, Dunlap SM, Zhu...at the time of sacrifice, including tumor, mammary fat pad, liver, visceral white adipose tissue, skin, and skeletal muscle (Task 1.d). All mice

Autonomy Level Specification for Intelligent Autonomous Vehicles

DTIC Science & Technology

2003-09-01

Autonomy Level Specification for Intelligent Autonomous Vehicles : Interim Progress Report Hui-Min Huang, Elena Messina, James Albus...Level Specification for Intelligent Autonomous Vehicles : Interim Progress Report 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

Theoretical Study of Hydrogen Adsorption on the GaN(0001) Surface

DTIC Science & Technology

2004-06-01

423 (1999) 70. [39] J.E. Northrup, J. Neugebauer, R.M. Feenstra, A.R. Smith, Phys. Rev. B 61 (2000) 9932. [40] K. Nakamura, T. Hayashi , A. Tachibana, K...Hasegawa, I.S.T. Tsong, T. Sakurai, T. Ohno , Phys. Rev. Lett. 82 (1999) 3074. [45] K. Raghavachari, Q. Fu, G. Chen, L. Li, C.H. Li, D.C. Law, R.F. Hicks, J...Xue, S. Kuwano, J.T. Sadowski, K.F. Kelly, T. Sakurai, T. Ohno , Phys. Rev. Lett. 84 (2000) 4015. [78] S. Vézian, F. Semond, J. Massies, D.W. Bullock, Z

"The Source of Learning Is Thought" Reading the "Chin-ssu lu" (???) with a "Western Eye"

ERIC Educational Resources Information Center

Reichenbach, Roland

2016-01-01

The contribution focuses on Neo-Confucian texts as collected by Zhu Xi (?? 1130-1200) and Lü Zuqian (1137-1181) and is a look from the "outside", from the perspective of German theories of Bildung ("self-cultivation"). It aims at demonstrating that among other insights that today's readers may gather from Neo-Confucian…

The Impacts of Remedial Interventions on Learning Chinese for Low-Achieving First Graders

ERIC Educational Resources Information Center

Chen, Shu-Li; Tzeng, Shih-Jay; Chu, Szu-Yin; Chen, Hsin-Ying

2016-01-01

The purpose of this study was to investigate whether a Chinese phonetic script, Zhu-Yin-Fu-Hao (ZYFH), influences low achievers in learning Chinese. In this quasi experimental design, 21 students were assigned to the experimental group, while the other 31 students were distributed to the control group. Two interventions were implemented throughout…

Implicit-shifted Symmetric QR Singular Value Decomposition of 3x3 Matrices

DTIC Science & Technology

2016-04-01

Graph 33, 4, 138:1– 138:11. TREFETHEN, L. N., AND BAU III, D. 1997. Numerical linear algebra , vol. 50. Siam. XU, H., SIN, F., ZHU, Y., AND BARBIČ, J...matrices with minimal branching and elementary floating point operations. Tech. rep., University of Wisconsin- Madison. SAITO, S., ZHOU, Z.-Y., AND

The Cat, the Cradle, and the Silver Spoon: Violence in Contemporary Art and the Question of Ethics for Art Education

ERIC Educational Resources Information Center

Tavin, Kevin; Kallio-Tavin, Mira

2014-01-01

Against the backdrop of objective and subjective violence, two contemporary artworks are interpreted through theories of the Other. Zhu Yu's "Eating People" (2000) is considered through Lacanian psychoanalytic theory and, in particular, through an Ethics of the Real. Teemu Mäki's "My Way, a Work in Progress" (1995) is…

Comments on "Another Look at the New York City Voucher Experiment."

ERIC Educational Resources Information Center

Myers, David E.; Mayer, Daniel P.

This brief paper is a response to a reanalysis (Krueger & Zhu, 2003) of a report (Mayer, Peterson, Myers, Tuttle, & Howell, 2002). The response is offered by two of the authors (Myers & Mayer) of the original report. The original report presented an evaluation of the impact of vouchers on students' reading and mathematics achievement…

Epilepsy and its Impact on psychosocial outcomes in Canadian children: Data from the National Longitudinal Study of Children and Youth (NLSCY).

PubMed

Prasad, A N; Corbett, B

2016-12-01

The purpose of this study was to use data from a population-based survey to evaluate the association between childhood epilepsy and social outcomes through tests of mathematics skills, and sense of general self-esteem (GSS). Using data from Cycles 1 to 8 of the National Longitudinal Survey of Children and Youth (NLSCY), Hierarchical linear modeling (HLM) was used to compare baseline math scores and changes in math scores and sense of general self esteem (GSS) over time in children with and without epilepsy. Scores of Health Utility Index (HUI) were factored into the analysis. Children with epilepsy do not significantly differ in their scaled math scores in comparison to their peers without epilepsy, at age 12; however, in the two level HLM model the children with epilepsy lagged behind the healthy comparison group in terms of their growth in acquiring knowledge in mathematics. Additionally, when children with epilepsy carry an added health impairment as measured by an imperfect health utility (HUI) score the group shows a slower rate of growth in their math scores over time. Self-esteem measures show variable effects in children with epilepsy alone, and those with added health impairments. The interaction with HUI scores shows a significant negative effect on self-esteem, when epilepsy is associated with added health impairment. The findings suggest that the population of Canadian children surveyed with epilepsy are vulnerable to poorer academic outcomes in mathematics in later years, and this problem is compounded further with the presence of other additional health impairments. Copyright © 2016 Elsevier B.V. All rights reserved.

Using magnons to probe spintronic materials properties

NASA Astrophysics Data System (ADS)

McMichael, Robert

2012-02-01

For many spin-based electronic devices, from the read sensors in modern hard disk drives to future spintronic logic concepts, the device physics originates in spin polarized currents in ferromagnetic metals. In this talk, I will describe a novel ``Spin Wave Doppler'' method that uses the interaction of spin waves with spin-polarized currents to determine the spin drift velocity and the spin current polarization [1]. Owing to differences between the band structures of majority-spin and minority-spin electrons, the electrical current also carries an angular momentum current and magnetic moment current. Passing these coupled currents though a magnetic wire changes the linear excitations of the magnetization, i.e spin waves. Interestingly, the excitations can be described as drifting ``downstream'' with the electron flow. We measure this drift velocity by monitoring the spin-wave-mediated transmission between pairs of periodically patterned antennas on magnetic wires as a function of current density in the wire. The transmission frequency resonance shifts by 2πδf = vk where the drift velocity v is proportional to both the current density and the current polarization P. I will discuss measurements of the spin polarization of the current in Ni80Fe20 [2], and novel alloys (CoFe)1-xGax [3] and (Ni80Fe20)1-xGdx [4]. [4pt] [1] V. Vlaminck and M. Bailleul, Science, 322, 410 (2008) [0pt] [2] M. Zhu, C. L. Dennis, and R. D. McMichael, Phys. Rev. B, 81, 140407 (2010). [0pt] [3] M. Zhu, B. D. Soe, R. D. McMichael, M. J. Carey, S. Maat, and J. R. Childress, Appl. Phys. Lett., 98, 072510 (2011). [0pt] [4] R. L. Thomas, M. Zhu, C. L. Dennis, V. Misra and R. D. McMichael, J. Appl. Phys., 110, 033902 (2011).

A revision of Petasiger Dietz, 1909 (Digenea: Echinostomatidae) and a key to its species.

PubMed

Faltýnková, Anna; Gibson, David I; Kostadinova, Aneta

2008-09-01

Petasiger Dietz, 1909 is revised, and a key to and lists of the records and hosts of the 18 recognised species are presented. The recognised species are: P. exaeretus Dietz, 1909, P. australis Johnston & Angel, 1941, P. combesi Zamparo, Overstreet & Brooks, 2005, P. floridus Premvati, 1968, P. grandivesicularis Ishii, 1935, P. islandicus Kostadinova & Skirnisson, 2007, P. johnstoni n. sp., P. megacanthus (Kotlán, 1922), P. minutissimus Gogate, 1934, P. neocomense Fuhrmann, 1927, P. nitidus Linton, 1928, P. novemdecim Lutz, 1928, P. oschmarini Kostadinova & Gibson, 1998, P. phalacrocoracis (Yamaguti, 1939), P. pseudoneocomense Bravo-Hollis, 1969, P. pungens (Linstow, 1894), P. soochowensis Ku, Chiu, Li & Zhu, 1977 and P. variospinosus (Odhner, 1910). Seven of these species are redescribed on the basis of type and newly collected material. P. laricola Ku, Chiu, Li & Zhu, 1977, Echinochasmus fotedari Chishti & Mir, 1989 and P. neocomense of Canković, Kazić & Milka (1983) are considered synonyms of P. pungens; P. longicirratus Ku, 1938, P. skrjabini Bashkirova, 1941 and P. nitidus of Chen et al. (1985) synonyms of P. neocomense; P. caribbensis Nassi, 1980 a synonym of P. novemdecim; and P. tientsinensis Ku, Chiu, Li & Zhu, 1977 a synonym of P. exaeretus. P. johnstoni n. sp. is described from Tachybaptus ruficollis novaehollandiae in Australia. It is readily distinguished from the most closely-related P. grandivesicularis Ishii, 1935 and P. australis Johnston & Angel, 1941 by the smaller size of the body and angle collar spines and differences in most other metrical characters. Species attributed to Petasiger which are here considered species inquirendae are: P. antigonus Nigam, 1944 sp. inq., P. chandleri Abdel-Malek, 1952 sp. inq., P. jubilarum Elperina in Skrjabin, Petrov & Bashkirova, 1947 sp. inq., P. nicolli Pande, 1939 sp. inq. and P. spasskyi Oshmarin in Skrjabin, Petrov & Bashkirova, 1947 sp. inq.; and Echinoparyphium inopinatum (Baer, 1959) n. comb. is a

Geochemical Characteristics of Granitoids in southwest Tianshan: Four Stages for Geodynamic Evolution of the Southwest Tianshan Orogenic Belt

NASA Astrophysics Data System (ADS)

Zhu, Y.

2016-12-01

Paleozoic intrusive rocks widely exposed in the west Tianshan orogenic belt provides key to understand the geodynamic evolution of the central Asian orogenic belt. A synthesis involving the data for Chinese Yili-central Tianshan and southwest Tianshan and comparison of Kyrgyz Tianshan with a broader dataset including zircon U-Pb ages, zircon Hf isotopic composition, major and trace elements for Paleozoic intrusions are presented to classify the Paleozoic intrusive rocks in four categories which corresponding to subduction of the Terskey Ocean, initial subduction stage of South Tianshan Ocean (STO), major subduction stage of the STO, and collisional to post-collisional stages. The subduction of the Terskey Oceanic crust finally caused the closure of the Terskey Ocean and the opening of the South Tianshan back-arc basin. The development of the Southwest Tianshan back-arc basin formed the STO, which subducted under the Yili-central Tianshan during early Silurian to early Carboniferous, and consequently formed huge arc magmatic rocks. Both the Silurian and early Carboniferous intrusions showing arc geochemical characteristics were derived from partial melting of juvenile arc-derived rocks with involvement of old continental crust. The STO finally closed by the end of early Carboniferous. Afterwards, geodynamic setting changed from convergence to extensional during late Carboniferous to early Permian periods. There is a significant geodynamic change from convergence to extension during late Carboniferous to early Permian, which may be resulted from breakoff of the subducted slab (Fig. 1). Such processes caused upwelling of asthenosphere and triggered partial melting of continental crust, as evidenced by emplacement of voluminous granitic rocks. References: An F, et al, 2013. Journal of Asian Earth Sciences, 78: 100-113; Zhu YF, 2011. Ore Geology Reviews, 40: 108-121; Zhu YF, et al, 2009. Geological Society, London, 166: 1085-1099; Zhu YF et al, 2016. Journal of Earth

Rapid Naming Speed and Chinese Character Recognition

ERIC Educational Resources Information Center

Liao, Chen-Huei; Georgiou, George K.; Parrila, Rauno

2008-01-01

We examined the relationship between rapid naming speed (RAN) and Chinese character recognition accuracy and fluency. Sixty-three grade 2 and 54 grade 4 Taiwanese children were administered four RAN tasks (colors, digits, Zhu-Yin-Fu-Hao, characters), and two character recognition tasks. RAN tasks accounted for more reading variance in grade 4 than…

Brain and Surface Warping via Minimizing Lipschitz Extensions (PREPRINT)

DTIC Science & Technology

2006-01-01

Angenent, S. Haker , A. Tannenbaum, and R. Kikinis, “Conformal geometry and brain flattening,” Proc. MICCAI, pp. 271-278, 1999. 1 [2] G. Aronsson, M...surface mapping,” IEEE Transactions on Medical Imaging, 23:7, 2004. 1 [17] S. Haker , L. Zhu, A. Tannenbaum, and S. An- genent, “Optimal mass transport for

Organization of the Optical Society of America Photonic Science Topical Meeting Series. Volume 3. The Microphysics of Surfaces: Beam-Induced Processes Held in Santa Fe, New Mexico on 11-13 February 1991

DTIC Science & Technology

1992-05-22

as semiconductor material. Impor- tant applications are thin film solar cells, thin film transistors for liquid crystal displays, photoreceptors for...171, 1989. 307-311 3 T.MINAMI, H.NANTO and S.TAKATA, Thin Solid Films, Vol.124, 1985. 43-47 4 D.Z.DA, F.R.ZHU and H.S.TANG, Acta Energiae Solaris

A Comparison of Various Estimators for Updating Forest Area Coverage Using AVHRR and Forest Inventory Data

Treesearch

Francis A. Roesch; Paul C. van Deusen; Zhiliang Zhu

1995-01-01

Various methods of adjusting low-cost and possibly biased estimates of percent forest coverage from AVHRR data with a subsample of higher-cost estimates from the USDA Forest Service's Forest Inventory and Analysis plots were investigated. Two ratio and two regression estimators were evaluated. Previous work (Zhu and Teuber, 1991) finding that the estimates from...

Measuring Components of Intelligence: Mission Impossible?

ERIC Educational Resources Information Center

Gregoire, Jacques

2013-01-01

The two studies conducted by Weiss, Keith, Zhu, and Chen in 2013 on the Wechsler Adult Intelligence Scale (WAIS-IV) and the Wechsler Intelligence Scale for Children (WISC-IV), respectively, provide strong evidence for the validity of a four-factor solution corresponding to the current hierarchical model of both scales. These analyses support the…

A Schedule-Based Approach for Flow-Control in Data Communication Networks

DTIC Science & Technology

1986-01-01

Tally Altes, Erdal Arikan , Carey Bunks, Isidro Castineyra, Julio Escobar, Eli Gafni, Ellen Hahne, Dan Helman, Patrick Hosein, Joe Hui, Atul Khanna...Tiedemann, Kevin Tsai, Paul Tseng, Paul Wiley, and Albert Wong. I have especially enjoyed many discussions with Ellen Hahne, Erdal Arikan , Jean Regnier

Prediction of Very High Reynolds Number Compressible Skin Friction

NASA Technical Reports Server (NTRS)

Carlson, John R.

1998-01-01

Flat plate skin friction calculations over a range of Mach numbers from 0.4 to 3.5 at Reynolds numbers from 16 million to 492 million using a Navier Stokes method with advanced turbulence modeling are compared with incompressible skin friction coefficient correlations. The semi-empirical correlation theories of van Driest; Cope; Winkler and Cha; and Sommer and Short T' are used to transform the predicted skin friction coefficients of solutions using two algebraic Reynolds stress turbulence models in the Navier-Stokes method PAB3D. In general, the predicted skin friction coefficients scaled well with each reference temperature theory though, overall the theory by Sommer and Short appeared to best collapse the predicted coefficients. At the lower Reynolds number 3 to 30 million, both the Girimaji and Shih, Zhu and Lumley turbulence models predicted skin-friction coefficients within 2% of the semi-empirical correlation skin friction coefficients. At the higher Reynolds numbers of 100 to 500 million, the turbulence models by Shih, Zhu and Lumley and Girimaji predicted coefficients that were 6% less and 10% greater, respectively, than the semi-empirical coefficients.

Recent advances on the tectonic and magmatic evolution of the Greater Tibetan Plateau: A special issue in honor of Prof. Guitang Pan

NASA Astrophysics Data System (ADS)

Zhu, Di-Cheng; Chung, Sun-Lin; Niu, Yaoling

2016-02-01

The Greater Tibetan Plateau, also known in China as the Qinghai-Tibet Plateau or the Qingzang Plateau, is a tectonic amalgamation of numbers of continental collision events from the northwest in the early Paleozoic to the southwest in the Cenozoic (cf. Dewey et al., 1988; Pan et al., 2012; Yin and Harrison, 2000). These collision events resulted in orogenic belts that record the prolonged albeit complex histories of opening and closing of Tethyan ocean basins and associated tectonic and magmatic responses (cf. Chung et al., 2005; Pan et al., 2012; Song et al., 2014; Yin and Harrison, 2000; Zhu et al., 2013, 2015). Although many aspects related to these events have been recently synthesized with elegance by Pan et al. (2012) and Zhu et al. (2013) using data and observations made available since 2000, many scientific questions, such as the duration of oceanic basins, the collisional and accretionary processes of different terranes, the processes responsible for crustal growth, and the mechanisms for economic mineralization, remain underdeveloped and require further investigations with additional data.

Theoretical and Experimental Study of Light Shift in a CPT-Based RB Vapor Cell Frequency Standard

DTIC Science & Technology

2001-01-01

Questions and Answers ROBERT LUTWAK (Datum): When you servo the microwave power to eliminate the light shift, what do you servo to? To what are you...leveling that signal? MIA0 ZHU: Do you mean what I servo to o r where did I do the servo? LUTWAK : What is the error signal that determines the TR

Formal matched asymptotics for degenerate Ricci flow neckpinches

NASA Astrophysics Data System (ADS)

Angenent, Sigurd B.; Isenberg, James; Knopf, Dan

2011-08-01

Gu and Zhu (2008 Commun. Anal. Geom. 16 467-94) have shown that type-II Ricci flow singularities develop from nongeneric rotationally symmetric Riemannian metrics on S^{n+1}\\,(n\\geq 2) . In this paper, we describe and provide plausibility arguments for a detailed asymptotic profile and rate of curvature blow-up that we predict such solutions exhibit.

My Classroom: China

ERIC Educational Resources Information Center

Gordon, Rebekah

2016-01-01

This article describes the teaching practice of two senior high school English teachers, Yu Huang and Yu Zhu. Their school is in Hezhang County--the No. 2 Middle School in the province of Guizhou. In China, most middle schools consist of six grades of students; the first three years are considered junior middle school and the latter three years…

Planning the future's forests with assisted migration [Chapter 8

Treesearch

Mary I. Williams; R. Kasten Dumroese

2016-01-01

If the climate changes faster than the adaptation or migration capability of plants (Zhu et al. 2012; Gray and Hamann 2013), foresters and other land managers will face an overwhelming challenge. Growing trees that survive may become more important than growing perfectly formed trees (Hebda 2008) and may require selection of adapted plant materials and/or assisting the...

The Flynn Effect and Its Critics: Rusty Linchpins and "Lookin' for g and Gf in Some of the Wrong Places"

ERIC Educational Resources Information Center

McGrew, Kevin S.

2010-01-01

The consensus of most intelligence scholars is that the Flynn effect (FE) is real, IQ test batteries are now routinely restandardized on a regular basis. A cornerstone in Flynn's explanation of the FE is his analysis of select Wechsler subtest scores across time. The featured articles by Kaufman and Zhou, Zhu, and Weiss question whether Flynn's…

Climatic change and assisted migration: Strategic options for forest and conservation nurseries

Treesearch

Mary I. Williams; R. Kasten Dumroese

2013-01-01

In light of current studies (for example, Gray and Hamann 2012; Zhu and others 2012) that show climate will change faster than plants can adapt or migrate naturally, it begs the question, "What does this mean for forestry, specifically forest and conservation nurseries?" Growing trees that just survive may become more important than promoting fast growth...

An Integrated Framework to Access and Mine Distributed Heterogeneous Data Streams with Uncertainty

DTIC Science & Technology

2015-05-13

Total Number: PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Discipline Chris chance 0.20 CS Chris Cosey 0.20 CS Brittney Mack 0.20 CS Tuan Nguyen...Conference, New York, NY, Feb. 2014. 38. X. Zhu, S. Song, J. Wang, J. Sun , and P.S. Yu, "Matching Heterogeneous Events with Patterns", Proc. IEEE Intl. Conf

A Summary of Proceedings for the Advanced Deployable Day/Night Simulation Symposium

DTIC Science & Technology

2009-07-01

initiated to design , develop, and deliver transportable visual simulations that jointly provide night-vision and high-resolution daylight capability. The...Deployable Day/Night Simulation (ADDNS) Technology Demonstration Project was initiated to design , develop, and deliver transportable visual...was Dr. Richard Wildes (York University); Mr. Vitaly Zholudev (Department of Computer Science, York University), Mr. X. Zhu (Neptec Design Group), and

[Xu Ren's Zhen jiu jing yan fang (Experiential recipe on acupuncture and moxibustion) and its spread].

PubMed

Wang, Zongxin

2002-07-01

The book, Zhen jiu jing yan fang (Experiential Recipe on Acupuncture and Moxibustion), written by Xu Ren, an imperial physician of Korea was completed in the 4th year of Renzu emperor (1644), and was an important work for the history of Korean acupuncture and moxibustion. However, there were mistakes on its writing date as described in the books of acu - moxibustion history in former reports. The portion of Mian xue tang zhen jiu ji cheng (Mianxuetang's Complete Work of Acupuncture and Moxibustion) universally recognized to be unique, was plagiarized from Zhen jiu jing yan fang.

Stable gray soliton pinned by a defect in a microcavity-polariton condensate.

PubMed

Chen, Ting-Wei; Hsieh, Wen-Feng; Cheng, Szu-Cheng

2015-09-21

We study the spatially localized dark state, called dark soliton, in a one-dimensional system of the non-resonantly pumped microcavity-polariton condensate (MPC). From the recent work by Xue and Matuszewski [Phys. Rev. Lett. 112, 216401 (2014)], we know that the dark soliton in the pure MPC system is unstable. But we find that a dark soliton pinned by a defect in the impure MPC becomes a gray soliton and can be stabilized by the presence of a defect. Moreover, the stable regime of the gray soliton is given in terms of the defect strength and pump parameter.

Detrital zircon U-Pb geochronology and provenance of the Carboniferous-Permian glaciomarine pebbly slates in the Tibetan Plateau

NASA Astrophysics Data System (ADS)

Wang, Q.; Zhu, D.; Zhao, Z.; Chung, S.; Li, C.; Sui, Q.; Fu, X.; Mo, X.

2011-12-01

Glaciomarine diamictites (including pebbly slate, pebbly siltstone, and pebbly sandstone) in the Tibetan Plateau are widely interpreted to have been associated with the deglaciation of the Indian continent. Guiding by zircon cathodoluminescence images, we determined U-Pb ages for detrital zircons from five typical Carboniferous-Permian pebbly slate samples from the Qiangtang, Lhasa, and Tethyan Himalaya of the Tibetan Plateau. The age distributions of detrital zircons from two samples (180 analyses) from Qiwu and Gangma Tso of the Qiangtang Terrane are similar, with two main age peaks ca. 579 and ca. 816 Ma and one minor age peak ca. 2490 Ma. Two samples (177 analyses) from Jiangrang and Damxung of the Lhasa Terrane define similar age distributions with two main age peaks ca. 539 and ca. 1175 Ma. Ages of detrital zircons from one sample (110 analyses) from Kangmar of the Tethyan Himalaya display main age peaks ca. 535, ca. 949, and ca. 2490 Ma. The ca. 816-Ma detrital zircons from the Qiangtang Terrane were most likely derived from the Lesser Himalaya, and the ca. 950-Ma detrital zircons from the Tethyan Himalaya might have been sourced from the High Himalaya, Eastern Ghats Province of the Indian plate and the Rayner Province of East Antarctica. The distinctive ca. 1175-Ma age population characteristic of zircons in the pebbly slates from the Lhasa Terrane is identical to the detrital zircons from the late Paleozoic sandstones (Zhu et al., 2011a) and the inherited zircons from the Mesozoic peraluminous granites (Zhu et al., 2011b) in this terrane, but significantly absent in the pebbly slates from both the Qiangtang and the Tethyan Himalayan terranes. The ca. 1175-Ma detrital zircons in the Lhasa Terrane were most likely sourced from the Albany-Fraser-Wilkes in southwestern Australia and East Antarctica. These new data obtained in this study reveal a distinct difference of detrital zircon provenance for the coeval Carboniferous-Permian glaciomarine pebbly slates

Considerations for the Development and Implementation of PDES (Product Data Exchange Specification) within a Government Environment

DTIC Science & Technology

1989-02-01

definition and manipulation languages. TECHNOLOGY TRANSFER: Contractor Personnel Actively Participate in PDES Activities: Yes, (Althoff & Chia Hui Shih...ORGANIZATION I) (2 (3) Mr. Bill Alzheimer Sandia National Labs X X Mr. Jeff Arthurs NAVSEA CEL-PA X Mr. Howard Bloom Nat’l Inst of Stds & Tech X LCDR

CBE Faculty and Staff

Science.gov Websites

About Us Research Staff Edward Arens Fred Bauman Gail Brager Darryl Dickerhoff Ali Ghahramani Uhl Zhe Wang Tom Webster Hui Zhang Research Affiliates Student Researchers Visiting Scholars Industry interdisciplinary group based in several academic departments, who collaborate regularly on research to improve the

A reference set of health utilities for long-term survivors of prostate cancer: population-based data from Ontario, Canada.

PubMed

Krahn, Murray D; Bremner, Karen E; Alibhai, Shabbir M H; Ni, Andy; Tomlinson, George; Laporte, Audrey; Naglie, Gary

2013-12-01

To measure quality of life (QOL) and utilities for prostate cancer (PC) patients and determine their predictors. A population-based, community-dwelling, geographically diverse sample of long-term PC survivors in Ontario, Canada, was identified from the Ontario Cancer Registry and contacted through their referring physician. Consenting patients completed questionnaires by mail: Health Utilities Index (HUI 2/3), Patient Oriented Prostate Utility Scale PORPUS-U (utility), PORPUS-P (health profile), Functional Assessment of Cancer Therapy-Prostate (FACT-P), and Prostate Cancer Index (PCI). Clinical data were obtained from chart reviews. Regression models determined the effects of a series of variables on QOL and utility. We received questionnaires and reviewed charts for 585 patients (mean age 72.6, 2-13 years postdiagnosis). Mean utility scores were as follows: PORPUS-U = 0.92, HUI2 = 0.85, and HUI3 = 0.78. Mean health profile scores were as follows: PORPUS-P = 71.7, PCI sexual, urinary, and bowel function = 23.7, 79.1, and 84.6, respectively (0 = worst, 100 = best), and FACT-P = 125.1 (0 = worst, 156 = best). In multiple regression analyses, comorbidity and PCI urinary, sexual, and bowel function were significant predictors of other QOL measures. With all variables, 32-50 % of the variance in utilities was explained. Many variables affect global QOL of PC survivors; only prostate symptoms and comorbidity have independent effects. Our model allows estimation of the effects of multiple factors on utilities. These utilities for long-term outcomes of PC and its treatment are valuable for decision/cost-effectiveness models of PC treatment.

Comparing population health in the United States and Canada

PubMed Central

2010-01-01

Background The objective of the paper is to compare population health in the United States (US) and Canada. Although the two countries are very similar in many ways, there are potentially important differences in the levels of social and economic inequality and the organization and financing of and access to health care in the two countries. Methods Data are from the Joint Canada/United States Survey of Health 2002/03. The Health Utilities Index Mark 3 (HUI3) was used to measure overall health-related quality of life (HRQL). Mean HUI3 scores were compared, adjusting for major determinants of health, including body mass index, smoking, education, gender, race, and income. In addition, estimates of life expectancy were compared. Finally, mean HUI3 scores by age and gender and Canadian and US life tables were used to estimate health-adjusted life expectancy (HALE). Results Life expectancy in Canada is higher than in the US. For those < 40 years, there were no differences in HRQL between the US and Canada. For the 40+ group, HRQL appears to be higher in Canada. The results comparing the white-only population in both countries were very similar. For a 19-year-old, HALE was 52.0 years in Canada and 49.3 in the US. Conclusions The population of Canada appears to be substantially healthier than the US population with respect to life expectancy, HRQL, and HALE. Factors that account for the difference may include access to health care over the full life span (universal health insurance) and lower levels of social and economic inequality, especially among the elderly. PMID:20429875

Outcomes at 7 years for babies who developed neonatal necrotising enterocolitis: the ORACLE Children Study.

PubMed

Pike, Katie; Brocklehurst, Peter; Jones, David; Kenyon, Sarah; Salt, Alison; Taylor, David; Marlow, Neil

2012-09-01

Within the ORACLE Children Study Cohort, the authors have evaluated long-term consequences of the diagnosis of confirmed or suspected neonatal necrotising enterocolitis (NEC) at age of 7 years. Outcomes were assessed using a parental questionnaire, including the Health Utilities Index (HUI-3) to assess functional impairment, and specific medical and behavioural outcomes. Educational outcomes for children in England were explored using national standardised tests. Multiple logistic regression was used to explore independent associates of NEC within the cohort. The authors obtained data for 119 (77%) of 157 children following proven or suspected NEC and compared their outcomes with those of the remaining 6496 children. NEC was associated with an increase in risk of neonatal death (OR 14.6 (95% CI 10.4 to 20.6)). At 7 years, NEC conferred an increased risk of all grades of impairment. Adjusting for confounders, risks persisted for any HUI-3 defined functional impairment (adjusted OR 1.55 (1.05, 2.29)), particularly mild impairment (adjusted OR 1.61 (1.03, 2.53)) both in all NEC children and in those with proven NEC, which appeared to be independent. No behavioural or educational associations were confirmed. Following NEC, children were more likely to suffer bowel problems than non-NEC children (adjusted OR 3.96 (2.06, 7.61)). The ORACLE Children Study provided opportunity for the largest evaluation of school age outcome following neonatal NEC and demonstrates significant long-term consequences of both gut function (presence of stoma, admission for bowel problems and continuing medical care for gut-related problems) and motor, sensory and cognitive outcomes as measured using HUI-3.

Gd-EOB-DTPA-enhanced MRI for monitoring future liver remnant function after portal vein embolization and extended hemihepatectomy: A prospective trial.

PubMed

Geisel, Dominik; Raabe, Philip; Lüdemann, Lutz; Malinowski, Maciej; Stockmann, Martin; Seehofer, Daniel; Pratschke, Johann; Hamm, Bernd; Denecke, Timm

2017-07-01

To evaluate changes in liver function after right portal vein embolization (PVE) and extended right hemihepatectomy using gadolinium ethoxybenzyl-DTPA-enhanced (Gd-EOB-DTPA) MRI. In this prospective trial, 37 patients undergoing PVE were examined before and 14 and 28 days after PVE and 10 days after extended hemihepatectomy using Gd-EOB-DTPA-enhanced MRI. Lobar volume, kinetic growth rate (KGR), relative enhancement (RE) as well as hepatocellular uptake index (HUI) and fat signal fraction (FSF) were calculated for each lobe. RE of the left liver lobe (LLL) was steadily increasing after PVE and decreased to 0.48 ± 0.19 10 days after surgery, which is significantly lower than 14 days and 28 days post PVE (P < 0.05). KGR was 14.06 ± 9.82%/week for the period from PVE to 14 days after PVE. HUI of the LLL increased steadily after PVE and was significantly higher at both 14 and 28 days after PVE compared to pre PVE (P < 0.05). HUI of the residual liver after surgery was lower than before. Gd-EOB-DTPA-enhanced MRI may be used to monitor the functional increase in the FLR after PVE and to depict the intraoperative liver injury leading to a decrease in liver remnant function. • The most significant FLR volume increase happens within the first 14 days. • No MRI parameter was able to predict the success of FLR growth. • Our data suggest an early resection about 14 days after PVE. • Routine Gd-EOB-DTPA-enhanced MRI might be suitable to replace ICG-test.

He Hui Whakatika: Culturally Responsive, Self Determining Interventions for Restoring Harmony

ERIC Educational Resources Information Center

Bateman, Sonja; Berryman, Mere

2008-01-01

The time has come for kaupapa Maori ideology and epistemology to move from the margins and claim legitimate space within the discipline of education. Kaupapa Maori ideology provides a dynamic framework within which Maori are better able to make meaning of the world and work for change. Increasingly, kaupapa Maori is being used to inform policies…

Solar Photochemistry | Chemistry and Nanoscience Research | NREL

Science.gov Websites

Publications Park, J.; Reid, O. G.; Blackburn, J. L.; Rumbles, G. Photoinduced Spontaneous Free-Carrier Wan, Y.; Guo, Z.; Zhu, T.; Yan, S.; Johnson, J.; Huang, L. Cooperative Singlet and Triplet Exciton . DOI: 10.1038/nchem.2348 Ihly, R.; Mistry, K. S.; Ferguson, A. J.; Clikeman, T. T.; Larson, B. W.; Reid

Justin Johnson | NREL

Science.gov Websites

Organic Framework," J. Phys. Chem. Lett. 7, 3660 (2016). Arias, D.; Ryerson, J.; Cook, J.; Damrauer , N.; Johnson, J., "Polymorphism Influences Singlet Fission Rates in Tetracene Thin Films," ; Chem. Sci. 7, 1185 (2016). Schrauben, J.N.; Zhao Y.; Mercado, C.; Ryerson, J.; Dron, P.; Michl, J.; Zhu

Federal Aviation Administration - Graphic TFR's

Science.gov Websites

NAVAJO CITY, NM, Saturday, May 26, 2018 through Tuesday, June 26, 2018 UTC New zoom to 8/4424 05/26/2018 8/4423 ZAB NM HAZARDS QUEEN, NM, Saturday, May 26, 2018 through Tuesday, June 26, 2018 UTC New zoom ZHU TX SECURITY Corpus Christi, TX, Tuesday, May 29, 2018 through Wednesday, May 30, 2018 Local zoom

Race--Social, Biological, or Lemonade?

ERIC Educational Resources Information Center

Carey, Gregory

2006-01-01

This paper presents comments on an article by R. L. Sternberg, E. L. Grigorenko, and K. K. Kidd and another article by H. Tang, T. Quertermous, B. Rodriguez, S. L. Kardia, X. Zhu, X., A. Brown, et al. (2005). On the day that the author of this paper reads Sternberg, Grigorenko, and Kidd's (January 2005) article on race, an article from the…

Global Military Operating Environments (GMOE) Phase I: Linking Natural Environments, International Security, and Military Operations

DTIC Science & Technology

2013-01-30

example from the Negev Desert, Israel, Journal of Geophysical Research, (05 2009): 1. doi: 01/14/2013 5.00 Michael Young, Eric McDonald, Jianting Zhu... radiation (incoming – reflected) x Solar Radiation Eppley Incoming solar radiation x Surface temperature IR Apogee Continuous surface...and electrical properties (dielectric permittivity and electrical conductivity). Additional measurements of solar radiation (four components), air

Global evaluation of ammonia bidirectional exchange and livestock diurnal variation schemes

EPA Pesticide Factsheets

There is no EPA generated dataset in this study.This dataset is associated with the following publication:Zhu, L., D. Henze, J. Bash , G. Jeong, K. Cady-Pereira, M. Shephard, M. Luo, F. Poulot, and S. Capps. Global evaluation of ammonia bidirectional exchange and livestock diurnal variation schemes. Atmospheric Chemistry and Physics. Copernicus Publications, Katlenburg-Lindau, GERMANY, 15: 12823-12843, (2015).

The Goldfish over the Rainbow

ERIC Educational Resources Information Center

Aguiar, Carlos E.; Santos, Antonio, C. F.; Lopes, Eric B.; Santos, Walter S.

2013-01-01

A goldfish isn't always visible inside its fishbowl. If the fish gets sufficiently close to the bowl glass, it will disappear for certain angles of observation. In a recent paper in this journal, Zhu and Shi explained the effect in terms of total internal reflection. We show in what follows that the phenomenon involves some richer optics: a…

Genetics Home Reference: autosomal dominant hyper-IgE syndrome

MedlinePlus

... binding domain of STAT3 cause hyper-IgE syndrome. Nature. 2007 Aug 30;448(7157):1058-62. Epub 2007 Aug 5. Citation on PubMed Renner ED, Torgerson TR, Rylaarsdam S, Añover-Sombke S, Golob K, LaFlam T, Zhu Q, Ochs HD. STAT3 mutation in the original patient with Job's syndrome. N Engl J Med. 2007 Oct 18; ...

Calibrating and Updating the Global Forest Products Model (GFPM version 2014 with BPMPD)

Treesearch

Joseph Buongiorno; Shushuai Zhu

2014-01-01

The Global Forest Products Model (GFPM) is an economic model of global production, consumption, and trade of forest products. An earlier version of the model is described in Buongiorno et al. (2003). The GFPM 2014 has data and parameters to simulate changes of the forest sector from 2010 to 2030. Buongiorno and Zhu (2014) describe how to use the model for simulation....

Calibrating and updating the Global Forest Products Model (GFPM version 2016 with BPMPD)

Treesearch

Joseph Buongiorno; Shushuai  Zhu

2016-01-01

The Global Forest Products Model (GFPM) is an economic model of global production, consumption, and trade of forest products. An earlier version of the model is described in Buongiorno et al. (2003). The GFPM 2016 has data and parameters to simulate changes of the forest sector from 2013 to 2030. Buongiorno and Zhu (2015) describe how to use the model for...

Beige Communication through Gap Junctions and Adaption by Autophagy.

PubMed

Enerbäck, Sven

2016-09-13

How thermogenic stimuli activate and control beige adipocytes is not fully understood. In this issue, Zhu et al. (2016) and Altshuler-Keylin et al. (2016) provide insights into these important issues by demonstrating roles for connexin 43 (Cx43) atg5 and atg12 in signal propagation and phenotypic adaptation in beige adipocytes. Copyright © 2016 Elsevier Inc. All rights reserved.

Investigation on the Development of Preschool Education Informationization of Ethnic Region in Gansu, China

ERIC Educational Resources Information Center

He, Yanhua

2015-01-01

This paper investigates the informationization situation of preschool education taking Linxia City in Gansu province. The analysis was conducted by the mean of questionnaire survey and individual interview which was collected in July 2013 in seven ethnic counties in Hui autonomous prefecture of Linxia. As a typical ethnic region, Linxia can…

National Centers for Environmental Prediction

Science.gov Websites

Modeling Mesoscale Modeling Marine Modeling and Analysis Teams Climate Data Assimilation Ensembles and Post Documentation, experiments, web content Nicole McKee Makefiles, scripts, launcher Edward Colon NEMSIO, post Yang GFS post Hui-ya Chuang NAM development Tom Black Dusan Jovic Jim Abeles GFS development S Moorthi

Theoretical Construction of Freedom and Pluralism Education in Pastoral Areas

ERIC Educational Resources Information Center

Zhao, Shuyan

2009-01-01

At beginning of the article, the author has a brief introduction of basic conditions in pastoral areas of Imperial Town, and interprets ethnic relations among Han, Tibetan, Mongolian, Yugur, Hui, Manchu and Tu mixed residence. After analysis of the internal and external factors that affect the specificity of pastoral education, the author…

Cultural Literacy and Student Engagement: The Case of Technical and Vocational Education and Training (TVET) in Hong Kong

ERIC Educational Resources Information Center

Hui, Sammy King Fai; Cheung, Hoi Yan

2015-01-01

Technical and vocational education and training (TVET) is often seen to be constraining and focused on specific skill development for specific occupations. This goal is at odds with the demands of a knowledge economy that requires more general educational outcomes for an uncertain and unpredictable labour market. For this reason, Hui (2012) has…

U.S. EPA, Pesticide Product Label, MR. HOLIDAY CALCIUM HYPOCHLORITE, 09/03/1985

EPA Pesticide Factsheets

2011-04-19

... QrdICfR- IIfT'r (')'rt.~>W!: ~i!"W- \\l'" It(I t,e 1lII\\IICI \\II., De hUI t1 s.~ ,), r, oec 11\\ flitS ~ ~tI ct ~ !"'- iIIl'31:J~ ~!Jet \\.'Id\\I lAd rI/JI:I. ~ ~~~ Ut .... " M:!.t ...

Diverse Data Sets for Impact

DTIC Science & Technology

2018-02-01

Defense Actions Against Test-Set Attacks”, In Proceedings of the Conference on Artificial Intelligence (AAAI), San Francisco, CA, February, 2017...Scott Alfeld, Jerry Zhu and Paul Barford. “Data Poisoning Attacks against Autoregressive Models”, In Proceedings of the Conference on Artificial ... Intelligence (AAAI), Phoenix, AZ, February, 2016. 7) Aaron Cahn, Scot Alfeld, Paul Barford and S. Muthukrishnan. “An Empirical Study of Web Cookies

A Platform to Optimize the Field Emission Properties of Carbon Nanotube Based Fibers (Postprint)

DTIC Science & Technology

2016-08-25

University of Dayton Research Institute 300 College Park Ave., Dayton, OH 45469 6) AFRL /RD, Kirtland AFB, Albuquerque, NM 8717... AFRL -RX-WP-JA-2017-0351 A PLATFORM TO OPTIMIZE THE FIELD EMISSION PROPERTIES OF CARBON-NANOTUBE-BASED FIBERS (POSTPRINT) Steven B...Fairchild AFRL /RX M. Cahay and W. Zhu University of Cincinnati K.L. Jensen Naval Research Laboratory R.G. Forbes University of Surrey

Functional Reflective Polarizer for Augmented Reality and Color Vision Deficiency

DTIC Science & Technology

2016-03-03

Functional reflective polarizer for augmented reality and color vision deficiency Ruidong Zhu, Guanjun Tan, Jiamin Yuan, and Shin-Tson Wu* College...polarizer that can be incorporated into a compact augmented reality system. The design principle of the functional reflective polarizer is explained and...augment reality system is relatively high as compared to a polarizing beam splitter or a conventional reflective polarizer. Such a functional reflective

Studies of the Effects of Perfluorocarbon Emulsions on Platelet Number and Function in Models of Critical Battlefield Injury

DTIC Science & Technology

2016-09-01

to treat traumatic injuries by enhanced delivery of oxygen . A concerned side effect of PFC may cause thrombocytopenia (TCYP). FDA requests...Morris, A., Zhu, J., Spiess, B.D., Parsons, J.T. The Effect of Perfluorocarbon Oxygen Therapeutics in a Sheep Survival Model of Severe Hemorrhagic...of effectively oxygenating sensitive tissue in the absence of adequate hemoglobin and/or blood flow. PFC emulsion volumes required for efficacy can

Obadiah Reid | NREL

Science.gov Websites

.; Boltalina, O. V.; Strauss, S. H.; Kopidakis, N.; Rumbles, G. Inter-Fullerene Electronic Coupling Controls .; Noel, N. K.; Reid, O. G.; Rumbles, G.; Kukura, P.; et al. Mechanism for Rapid Growth of Organic Organic Framework. J. Phys. Chem. Lett. 2016, 7, 3660-3665. Reid, O. G.; Yang, M.; Kopidakis, N.; Zhu, K

Establishment of Health Utility Indices for Post-Infectious Functional Gastrointestinal Disorders in Active Duty US Military.

PubMed

Porter, Chad K; Thura, Nadia; Schlett, Carey D; Sanders, John W; Tribble, David R; Monteville, Marshall R; Riddle, Mark S

2015-01-01

Knowledge of disease burden attributable to functional gastrointestinal disorders (FGD) in travelers is lacking, despite the high incidence of travelers' diarrhea (TD) associated with increased FGD risk. One tool for assessing the impact of disease on health-related quality of life is the health utility index (HUI), which values health states based on preferential health outcomes. Health utilities can be used as preference weights in the estimation of quality-adjusted life-years (QALYs). Six months following travel to Egypt or Turkey, 120 US military personnel completed a survey on TD during deployment, health-related quality of life (SF-36), and the onset of functional bowel disorders (Rome II). Elements from the SF-36 were used to develop SF-6D values, which were combined with health state valuations to enable calculation of HUI scores for each subject. Mean index scores were compared across functional outcomes, specific symptoms, and demographic profiles. The presence of FGD significantly reduced index scores, with irritable bowel syndrome (IBS) and dyspepsia showing the greatest impact (-0.17 and -0.19, respectively) compared with those with no FGD (p < 0.05). Importantly, however, several individuals met multiple FGD outcome definitions. Additionally, a number of symptoms associated with abnormal bowel habits and abdominal pain were associated with reduced index scores regardless of outcome. FGD are associated with significant morbidity as assessed by HUIs. Given the strong link between TD and FGD as well as the large number of travelers from the developed to the developing world, additional study is needed to further understand this association and efforts aimed at primary disease prevention are warranted. Published 2015. This article has been contributed to by US Government employees and their work is in the public domain in the USA.

Massively parallel sequencing of 124 SNPs included in the precision ID identity panel in three East Asian minority ethnicities.

PubMed

Liu, Jing; Wang, Zheng; He, Guanglin; Zhao, Xueying; Wang, Mengge; Luo, Tao; Li, Chengtao; Hou, Yiping

2018-07-01

Massively parallel sequencing (MPS) technologies can sequence many targeted regions of multiple samples simultaneously and are gaining great interest in the forensic community. The Precision ID Identity Panel contains 90 autosomal SNPs and 34 upper Y-Clade SNPs, which was designed with small amplicons and optimized for forensic degraded or challenging samples. Here, 184 unrelated individuals from three East Asian minority ethnicities (Tibetan, Uygur and Hui) were analyzed using the Precision ID Identity Panel and the Ion PGM System. The sequencing performance and corresponding forensic statistical parameters of this MPS-SNP panel were investigated. The inter-population relationships and substructures among three investigated populations and 30 worldwide populations were further investigated using PCA, MDS, cladogram and STRUCTURE. No significant deviation from Hardy-Weinberg equilibrium (HWE) and Linkage Disequilibrium (LD) tests was observed across all 90 autosomal SNPs. The combined matching probability (CMP) for Tibetan, Uygur and Hui were 2.5880 × 10 -33 , 1.7480 × 10 -35 and 4.6326 × 10 -34 respectively, and the combined power of exclusion (CPE) were 0.999999386152271, 0.999999607712827 and 0.999999696360182 respectively. For 34 Y-SNPs, only 16 haplogroups were obtained, but the haplogroup distributions differ among the three populations. Tibetans from the Sino-Tibetan population and Hui with multiple ethnicities with an admixture population have genetic affinity with East Asian populations, while Uygurs of a Eurasian admixture population have similar genetic components to the South Asian populations and are distributed between East Asian and European populations. The aforementioned results suggest that the Precision ID Identity Panel is informative and polymorphic in three investigated populations and could be used as an effective tool for human forensics. Copyright © 2018 Elsevier B.V. All rights reserved.

Tragedy at Virginia Tech: Trauma and Its Aftermath

ERIC Educational Resources Information Center

Flynn, Christopher; Heitzmann, Dennis

2008-01-01

While college campuses are relatively safe environments, the promise of safety and security on campus was shattered by a single gunman on April 16, 2007. Seung-Hui Cho, a senior at Virginia Tech, shot 49 students and faculty, killing 32, before killing himself. The authors are psychologists and directors of university counseling centers; they…

Sensory quality evaluation for appearance of needle-shaped green tea based on computer vision and nonlinear tools*

PubMed Central

Dong, Chun-wang; Zhu, Hong-kai; Zhao, Jie-wen; Jiang, Yong-wen; Yuan, Hai-bo; Chen, Quan-sheng

2017-01-01

Tea is one of the three greatest beverages in the world. In China, green tea has the largest consumption, and needle-shaped green tea, such as Maofeng tea and Sparrow Tongue tea, accounts for more than 40% of green tea (Zhu et al., 2017). The appearance of green tea is one of the important indexes during the evaluation of green tea quality. Especially in market transactions, the price of tea is usually determined by its appearance (Zhou et al., 2012). Human sensory evaluation is usually conducted by experts, and is also easily affected by various factors such as light, experience, psychological and visual factors. In the meantime, people may distinguish the slight differences between similar colors or textures, but the specific levels of the tea are hard to determine (Chen et al., 2008). As human description of color and texture is qualitative, it is hard to evaluate the sensory quality accurately, in a standard manner, and objectively. Color is an important visual property of a computer image (Xie et al., 2014; Khulal et al., 2016); texture is a visual performance of image grayscale and color changing with spatial positions, which can be used to describe the roughness and directivity of the surface of an object (Sanaeifar et al., 2016). There are already researchers who have used computer visual image technologies to identify the varieties, levels, and origins of tea (Chen et al., 2008; Xie et al., 2014; Zhu et al., 2017). Most of their research targets are crush, tear, and curl (CTC) red (green) broken tea, curly green tea (Bilochun tea), and flat-typed green tea (West Lake Dragon-well green tea) as the information sources. However, the target of the above research is to establish a qualitative evaluation method on tea quality (Fu et al., 2013). There is little literature on the sensory evaluation of the appearance quality of needle-shaped green tea, especially research on a quantitative evaluation model (Zhou et al., 2012; Zhu et al., 2017). PMID:28585431

Sensory quality evaluation for appearance of needle-shaped green tea based on computer vision and nonlinear tools.

PubMed

Dong, Chun-Wang; Zhu, Hong-Kai; Zhao, Jie-Wen; Jiang, Yong-Wen; Yuan, Hai-Bo; Chen, Quan-Sheng

2017-06-01

Tea is one of the three greatest beverages in the world. In China, green tea has the largest consumption, and needle-shaped green tea, such as Maofeng tea and Sparrow Tongue tea, accounts for more than 40% of green tea (Zhu et al., 2017). The appearance of green tea is one of the important indexes during the evaluation of green tea quality. Especially in market transactions, the price of tea is usually determined by its appearance (Zhou et al., 2012). Human sensory evaluation is usually conducted by experts, and is also easily affected by various factors such as light, experience, psychological and visual factors. In the meantime, people may distinguish the slight differences between similar colors or textures, but the specific levels of the tea are hard to determine (Chen et al., 2008). As human description of color and texture is qualitative, it is hard to evaluate the sensory quality accurately, in a standard manner, and objectively. Color is an important visual property of a computer image (Xie et al., 2014; Khulal et al., 2016); texture is a visual performance of image grayscale and color changing with spatial positions, which can be used to describe the roughness and directivity of the surface of an object (Sanaeifar et al., 2016). There are already researchers who have used computer visual image technologies to identify the varieties, levels, and origins of tea (Chen et al., 2008; Xie et al., 2014; Zhu et al., 2017). Most of their research targets are crush, tear, and curl (CTC) red (green) broken tea, curly green tea (Bilochun tea), and flat-typed green tea (West Lake Dragon-well green tea) as the information sources. However, the target of the above research is to establish a qualitative evaluation method on tea quality (Fu et al., 2013). There is little literature on the sensory evaluation of the appearance quality of needle-shaped green tea, especially research on a quantitative evaluation model (Zhou et al., 2012; Zhu et al., 2017).

Provenance evolution in the northern South China Sea and its implication of paleo-drainage systems from Eocene to Miocene

NASA Astrophysics Data System (ADS)

Cui, Y.; Shao, L.; Qiao, P.

2017-12-01

Geochemistry analysis and detrital zircon U-Pb geochronology aim to fully investigate the "source to sink" patterns of northern South China Sea (SCS) from Eocene to Miocene. Evolutional history of the surrounding drainage system has been highly focused on, in comparison to sedimentary characteristics of the SCS basins. Rapid local provenances were prevailed while large-scale fluvial transport remained to evolve during Eocene. Since early Oligocene, sediments from the South China were more abundantly delivered to the northeastern Pearl River Mouth Basin in addition to Dongsha volcanism supplement. Aside from intrabasinal provenances, long-distance transport started to play significant role in Zhu1 Depression, possibly reaching western and southern Baiyun Sag, partially. Western Qiongdongnan Basin might accept sediments from central Vietnam with its eastern area more affected from Hainan Island and Southern Uplift. In the late Oligocene, due to drastic sea-level changes and rapid exhumation, mafic to altramafic sediments were transported in abundance to Central Depression from Kontum Massif, while multiple provenances casted integrated influence on eastern sedimentary sequences. Southern Baiyun Sag was also affected by an increased supplement from the west Shenhu Uplift or even central Vietnam. Overall pattern did not change greatly since early Miocene, but long-distance transport has become dominant in the northern SCS. Under controlled by regional tectonic cycles, Pearl River gradually evolved into the present scale and exerted its influence on basinal provenances by several stages. Zhu1 Depression was partially delivered sediments from its tributaries in early Oligocene while northern Zhu2 Depression has not been provided abundant materials until late Oligocene. Meanwhile, although detailed transportation routine remains uncertain and controversial, an impressive paleo-channel spanning the whole Qiongdongnan Basin was presumed to supply huge amount of mafic to

Non-Darcy flow of water-based carbon nanotubes with nonlinear radiation and heat generation/absorption

NASA Astrophysics Data System (ADS)

Hayat, T.; Ullah, Siraj; Khan, M. Ijaz; Alsaedi, A.; Zaigham Zia, Q. M.

2018-03-01

Here modeling and computations are presented to introduce the novel concept of Darcy-Forchheimer three-dimensional flow of water-based carbon nanotubes with nonlinear thermal radiation and heat generation/absorption. Bidirectional stretching surface induces the flow. Darcy's law is commonly replace by Forchheimer relation. Xue model is implemented for nonliquid transport mechanism. Nonlinear formulation based upon conservation laws of mass, momentum and energy is first modeled and then solved by optimal homotopy analysis technique. Optimal estimations of auxiliary variables are obtained. Importance of influential variables on the velocity and thermal fields is interpreted graphically. Moreover velocity and temperature gradients are discussed and analyzed. Physical interpretation of influential variables is examined.

Insecure? Keeping New England Campuses Safe

ERIC Educational Resources Information Center

Franzosa, Alyssa

2009-01-01

On April 16, 2007, Seung-Hui Cho traded in his title as "student" for one of "gunman." That day, Cho, a student at Virginia Tech, was responsible for the deadliest shooting spree by a single person in U.S. history, killing 33 people, including himself. Ten months later on Valentine's Day, Steven Kazmierczak joined Cho in the…

2007: A Year In Review

ERIC Educational Resources Information Center

Diverse: Issues in Higher Education, 2007

2007-01-01

The most high-profile story of the year touching the higher education community was undisputedly the killings at Virginia Tech in April when student Seung-Hui Cho opened fire, leaving 33 people dead, including himself. To date, it is the deadliest campus shooting in U.S. history. However, in September, the Delaware State University (DSU) community…

State-of-the-art technologies of forest inventory and monitoring in Taiwan

Treesearch

Fong-Long Feng

2000-01-01

Ground surveys, remote sensing (RS), global positioning systems (GPS), geographic information systems (GIS), and permanent sampling plots (PSP) were used to inventory and monitor forests in the development of an ecosystem management plan for the island of Taiwan. While the entire island has been surveyed, this study concentrates on the Hui-Sun and Hsin-Hua Experimental...

School Violence Case Study at Virginia Tech

ERIC Educational Resources Information Center

Lyttle, LeighAnne

2012-01-01

On April 16, 2007, Seung Hui Cho, a livid and mentally ill student, shot to death 32 students and faculty of Virginia Tech, wounded many more people, and then killed himself. This incident has impacted college and university campuses nationwide in efforts to seek mentally disturbed students and help them, to have effective emergency teams, as well…

XueQian ErTong FaZhan PingGu (Assessing the Development of Preschoolers). ERIC Digest.

ERIC Educational Resources Information Center

Katz, Lilian G.

To help parents address those aspects of their child's development which may need special encouragement, support, or intervention, this digest delineates 11 categories of behavior for assessment. Parents should not be alarmed if their children are having difficulty in only a few categories, and they should not judge their children's permanent…

Novel Gbeta Mimic Kelch Proteins Gpb1 and Gpb2 Connect G-Protein Signaling to Ras via Yeast Neurofibromin Homologs Ira 1 and Ira 2: A Model for Human NF1

DTIC Science & Technology

2006-03-01

Introduction Molecular switches composed of G-protein coupled receptors (GPCRs) and associated heterotrimeric G proteins transduce extracellular stimuli...We are investigating the molecular mechanisms by which the Ras GAP activity of the yeast neurofibromin homologs Ira1/2 is regulated as a model to...NF1 (For reviews, see Dasgupta and Gutmann, 2003; Parada, 2000; Zhu and Parada, 2002). It is therefore critical to elucidate the molecular mechanisms

The Regulation of Nucleolin Expression in Prostrate Epithelial Cells; Possible Involvement of MYC

DTIC Science & Technology

2002-01-01

SH Yeh, NH (1993). The self-cleaving activity of nucleolin determines its molecular dynamics in relation to cell proliferation. Exp Cell Res 208: 48... complementarity were mixed with a segment encompassing the two Nucleolin domains (p50), the rate with which the strands annealed was significantly enhanced...a recent study (Zhu et al 1999) that Nucleolin with all its phosphorylation sites mutated could localize during mitosis as wild-type Nucleolin did

China Report: Political, Sociological and Military Affairs. No. 429

DTIC Science & Technology

1983-06-10

according to the number of strokes in the family name. Wang Wei, (Wang Dachuan), (Wang Xinmin), Lu Liang, Lu Yukun, Zhu Danhua (female), (Liu Jiufeng...Li Shanyuan), He Shikun, (Shen Gan), Shen Hanqing, (Du Shijiu), Lu Xiaopeng, (Pu Jiguang), (Zhang Yulong), (Zhang Xiren), (Zhang Xiuxi), (Zhang...the session in accordance with the CPPCC Constitution. Wu Ping was elected chairman and Li Shizhang, Gu Jiguang, He Shikun, Lu Xiaopeng, Shen

An Intervention Study on Screening for Breast Cancer Among Single African-American Women Aged 65 and Older

DTIC Science & Technology

1999-09-01

Since the single constitute 75% of African-American women aged 65 and older , and the incidence and mortality of cancer are especially high in elderly ...Breast Cancer Among Single African-American Women Aged 65 and Older PRINCIPAL INVESTIGATOR: Kangmin Zhu, M.D., Ph.D. CONTRACTING ORGANIZATION: Meharry...to improve the breast screening behavior among single African-American women ages 65 and older . During the period, we (1) finished post-intervention

Journey Through Statistical Mechanics

NASA Astrophysics Data System (ADS)

Yang, C. N.

2013-05-01

My first involvement with statistical mechanics and the many body problem was when I was a student at The National Southwest Associated University in Kunming during the war. At that time Professor Wang Zhu-Xi had just come back from Cambridge, England, where he was a student of Fowler, and his thesis was on phase transitions, a hot topic at that time, and still a very hot topic today...

The Conference on the Dynamics of Molecular Collisions Held in Oglebay Park, Wheeling, West Virginia on 12-17 July 1987.

DTIC Science & Technology

1987-07-17

Yuhua Guan, Gillian C. Lynch and Donald L. Thompson Department of Chemistry, Oklahoma State University, Stillwater, OK 74078 Classical trajectories...P20 PHOTOFRAGMrTATION OF ALKYL IODIDES -- Photofragmentation Channels and Energy Partitioning of the Fragments Qihe Zhu, Shouling Huang, J.R. Cao , Ye...Chemistry (314) 553-5344 Upton, NY 11973 (516) 282-4348 Dr. William L. Hase Wayne State University Dr. Yuhua Guan 435 Chemistry Department of Chemistry

Effects of Enhanced Oxygen Delivery by Perfluorocarbons in Spinal Cord Injury

DTIC Science & Technology

2013-01-01

spinal cord ischemia. Acta Med Okayama 1997; 51:71–77. 10. Daugherty WP, Levasseur JE, Sun D, Spiess BD, Bullock MR: Perfluorocarbon emulsion improves...cerebral oxygenation and mitochondrial function after fluid percussion brain injury in rats. Neurosurgery 2004; 54:1223–1230. 11. Spiess B...2008; 2: 213-20. 13. Zhou Z, Sun D, Levasseur JE, Merenda A, Hamm RJ, Zhu J, Spiess BD, Bullock MR. Perfluorocarbon emulsions improve cognitive

Le probleme des valeurs a l'ecole française aujourd'hui

NASA Astrophysics Data System (ADS)

Legrand, Louis

1995-01-01

Since the 1960s the French public school system has virtually abandoned the attempt to teach moral values, leaving students morally disoriented. The author finds this situation profoundly unhealthy and argues that schools have a responsibility to help in developing the ability of pupils to make moral choices and act accordingly. He rejects the rationalist view that science makes traditional morality unnecessary. At the same time, he recognizes the moral value of the scientific respect of truth and objectivity. He argues for a form of moral education which would inculcate respect for different points of view, cultural norms and religious beliefs, and which would not shy away from addressing morally important issues such as drag abuse, violence, sexuality, social justice, poverty, racism and environmental pollution.

VizieR Online Data Catalog: z>~5 AGN in Chandra Deep Field-South (Weigel+, 2015)

NASA Astrophysics Data System (ADS)

Weigel, A. K.; Schawinski, K.; Treister, E.; Urry, C. M.; Koss, M.; Trakhtenbrot, B.

2015-09-01

The Chandra 4-Ms source catalogue by Xue et al. (2011, Cat. J/ApJS/195/10) is the starting point of this work. It contains 740 sources and provides counts and observed frame fluxes in the soft (0.5-2keV), hard (2-8keV) and full (0.5-8keV) band. All object IDs used in this work refer to the source numbers listed in the Xue et al. (2011, Cat. J/ApJS/195/10) Chandra 4-Ms catalogue. We make use of Hubble Space Telescope (HST)/Advanced Camera for Surveys (ACS) data from the Great Observatories Origins Deep Survey South (GOODS-south) in the optical wavelength range. We use catalogues and images for filters F435W (B), F606W (V), F775W (i) and 850LP (z) from the second GOODS/ACS data release (v2.0; Giavalisco et al., 2004, Cat. II/261). We use Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS) Wide Field Camera 3 (WFC3)/infrared data from the first data release (DR1, v1.0) for passbands F105W (Y), F125W (J) and F160W (H) (Grogin et al., 2011ApJS..197...35G; Koekemoer et al., 2011ApJS..197...36K). To determine which objects are red, dusty, low-redshift interlopers, we also include the 3.6 and 4.5 micron Spitzer Infrared Array Camera (IRAC) channels. We use SIMPLE image data from the DR1 (van Dokkum et al., 2005, Spitzer Proposal, 2005.20708) and the first version of the extended SIMPLE catalogue by Damen et al. (2011, Cat. J/ApJ/727/1). (6 data files).

WEIGHING THE GALACTIC DARK MATTER HALO: A LOWER MASS LIMIT FROM THE FASTEST HALO STAR KNOWN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Przybilla, Norbert; Tillich, Alfred; Heber, Ulrich

2010-07-20

The mass of the Galactic dark matter halo is under vivid discussion. A recent study by Xue et al. revised the Galactic halo mass downward by a factor of {approx}2 relative to previous work, based on the line-of-sight velocity distribution of {approx}2400 blue horizontal-branch (BHB) halo stars. The observations were interpreted with a statistical approach using cosmological galaxy formation simulations, as only four of the six-dimensional phase-space coordinates were determined. Here we concentrate on a close investigation of the stars with the highest negative radial velocity from that sample. For one star, SDSSJ153935.67+023909.8 (J1539+0239 for short), we succeed in measuringmore » a significant proper motion, i.e., full phase-space information is obtained. We confirm the star to be a Population II BHB star from an independent quantitative analysis of the Sloan Digital Sky Survey (SDSS) spectrum-providing the first non-LTE (NLTE) study of any halo BHB star-and reconstruct its three-dimensional trajectory in the Galactic potential. J1539+0239 turns out to be the fastest halo star known to date, with a Galactic rest-frame velocity of 694{sup +300}{sub -221} km s{sup -1} (full uncertainty range from Monte Carlo error propagation) at its current position. The extreme kinematics of the star allows a significant lower limit to be put on the halo mass in order to keep it bound, of M {sub halo} {>=} 1.7{sup +2.3}{sub -1.1} x 10{sup 12} M{sub sun}. We conclude that the Xue et al. results tend to underestimate the true halo mass as their most likely mass value is consistent with our analysis only at a level of 4%. However, our result confirms other studies that make use of the full phase-space information.« less

Acupuncture lowering blood pressure for secondary prevention of stroke: a study protocol for a multicenter randomized controlled trial.

PubMed

Du, Yu-Zheng; Gao, Xin-Xin; Wang, Cheng-Ting; Zheng, Hai-Zhen; Lei, Yun; Wu, Meng-Han; Shi, Xue-Min; Ban, Hai-Peng; Gu, Wen-Long; Meng, Xiang-Gang; Wei, Mao-Ti; Hu, Chun-Xiao

2017-09-15

Stroke is the prime cause of morbidity and mortality in the general population, and hypertension will increase the recurrence and mortality of stroke. We report a protocol of a pragmatic randomized controlled trial (RCT) using blood pressure (BP)-lowering acupuncture add-on treatment to treat patients with hypertension and stroke. This is a large-scale, multicenter, subject-, assessor- and analyst-blinded, pragmatic RCT. A total of 480 patients with hypertension and ischemic stroke will be randomly assigned to two groups: an experimental group and a control group. The experimental group will receive "HuoXueSanFeng" acupuncture combined with one antihypertensive medication in addition to routine ischemic stroke treatment. The control group will only receive one antihypertensive medication and basic treatments for ischemic stroke. HuoXueSanFeng acupuncture will be given for six sessions weekly for the first 6 weeks and three times weekly for the next 6 weeks. A 9-month follow-up will, thereafter, be conducted. Antihypertensive medication will be adjusted based on BP levels. The primary outcome will be the recurrence of stroke. The secondary outcomes including 24-h ambulatory BP, the TCM syndrome score, the Short Form 36-item Health Survey (SF-36), the National Institute of Health Stroke Scale (NIHSS), as well as the Barthel Index (BI) scale will be assessed at baseline, 6 weeks and 12 weeks post initiating treatments; cardiac ultrasound, carotid artery ultrasound, transcranial Doppler, and lower extremity ultrasound will be evaluated at baseline and 12 weeks after treatment. The safety of acupuncture will also be assessed. We aim to determine the clinical effects of controlling BP for secondary prevention of stroke with acupuncture add-on treatment. ClinicalTrials.gov, ID: NCT02967484 . Registered on 13 February 2017; last updated on 27 June 2017.

Supplementary catalogue of the Anthomyiidae (Diptera) of China

PubMed Central

Wang, Mengmeng; Michelsen, Verner; Li, Kai; Zhu, Weibing

2014-01-01

Abstract The present catalogue of Anthomyiidae attempts to list all species (173) described or recorded from mainland China (165) and Taiwan (8) that for various reasons are not treated in “Flies of China” from 1998. The catalogue further lists Chinese species that are presently standing in new generic combinations compared to those of “Flies of China”, species that have changed name because of synonymy or misidentification, and species upgraded from subspecies to species. Regional distribution by province is specified for all species. Literature sources to descriptions or records of anthomyiid species from China are only given for those 173 species not covered by “Flies of China”. Four new combinations are proposed: Enneastigma fulva (Malloch, 1934), Enneastigma henanensis (Ge & Fan, 1982), Enneastigma lengshanensis (Xue, 2001) and Hylemya qinghaiensis (Fan, Chen & Ma, 1989). Eremomyia turbida Huckett, 1951 is revived from synonymy with Chortophila triticiperda Stein, 1900 (current name Eutrichota turbida). One subspecies is upgraded to species: Adia asiatica Fan, 1988. The following eight new synonymies are proposed: Delia pectinator fuscilateralis Fan in Fan & Zheng, 1992 with Delia pectinator Suwa, 1984; Eremomyia pilimana pilimarginata Fan & Qian in Fan, Chen, Ma & Ge, 1982 with Eremomyia turbida Huckett, 1951 (current name Eutrichota turbida); Lopesohylemya Fan, Chen & Ma, 1989 with Hylemya Robineau-Desvoidy, 1830; Deliomyia Fan in Fan et al., 1988 with Subhylemyia Ringdahl, 1933; Hydrophoria disticrassa Xue & Bai, 2009 with Hydrophoria pullata Wu, Liu & Wei, 1995 (current name Zaphne pullata); Heteroterma Wei, 2006 with Scathophaga Meigen, 1803; Heteroterma fanjingensis Wei, 2006 with Scathophaga curtipilata Feng, 2002; Scatomyza fansipanicola Ozerov in Ozerov & Krivosheina, 2011 with Scathophaga curtipilata Feng, 2002. The genus Heteroterma Wei, 2006 and species Heteroterma fanjingensis Wei, 2006 are reassigned from Anthomyiidae to

CLAS g10 Analysis on Single Photopion Productions from Deuterium

NASA Astrophysics Data System (ADS)

Chen, Wei

2006-04-01

Photopion productions from nucleons are essential probes of the transition from meson-nucleon degrees of freedom to quark-gluon degrees of freedom in exclusive processes. The cross sections of these processes are also advantageous, for the investigation of the oscillatory behavior around the quark counting prediction, since they decrease relatively slower with energy compared with other photon-induced processes. Recent data from JLab experiment E94-104 [1,2] show dramatic change in the scaled differential cross-section from the γn ->&-circ;p and γp ->&+circ;n processes in the center of mass energy between 1.8 GeV to about 2.4 GeV. We are carrying out a CLAS approved analysis [3] of the JLab CLAS g10 data on the γn ->&-circ;p to investigate this dramatic behavior in much finer photon energy bins. Furthermore, the angular dependence of the scaling behavior for this process will also be studied in detail. We will report the status of the analysis in this presentation. References: [1] L.Y. Zhu et al., Phys. Rev. Lett. 91, 022003 (2003).[2] L.Y. Zhu et al., Phys. Rev. C 71, 044603 (2005); nucl-ex/0409018.[3] http://www.tunl.duke.edu/˜mep/clas/caapion.pdf

A Stochastic Optimization Algorithm using Intelligent Agents: With Constraints and Rate of Convergence

DTIC Science & Technology

2010-11-01

Novembre 2010. Contexte: La puissance des ordinateurs nous permet aujourd’hui d’étudier des problèmes pour lesquels une solution analytique n’existe... 13 4.8 Proof of Corollary........................................................................................................ 13 ...optimal capacities for links. e DRDC CORA TM 2010-249 13 4.9 Example Figure 4 below shows that the probability of achieving the optimal

Educare for the Elderly: Hawaii's Post 60 Students Respond to a Trial Humanities Course.

ERIC Educational Resources Information Center

Cox, Clarice Robinson

In April and May 1974, the Center of Continuing Education and Community Service of the University of Hawaii at Hilo sponsored a course for 41 members of the Hui Aloha senior citizens club. Between 39 and 44 students, ranging in age from 60 to 93, participated in an experimental workshop program which involved four 8-hour tours of colleges and…

Two new species of Oxycera (Diptera, Stratiomyidae) from Ningxia, China.

PubMed

Zai-Hua, Yang; Jin-Yong, Yu; Mao-Fa, Yang

2012-01-01

Two new speices, Oxycera rozkosnyisp. n. and Oxycera ningxiaensissp. n., are described from Liupanshan Nature Reserve, Ningxia Hui Autonomous Region, Northwest China. All essential diagnostic characters are figured and possible relationships of both taxa are briefly discussed, and a new key to species of Oxycera from China. The type specimens are deposited in the Institute of Entomology, Guizhou University, Guiyang (GUGC).

Efficient gene knock-out and knock-in with transgenic Cas9 in Drosophila.

PubMed

Xue, Zhaoyu; Ren, Mengda; Wu, Menghua; Dai, Junbiao; Rong, Yikang S; Gao, Guanjun

2014-03-21

Bacterial Cas9 nuclease induces site-specific DNA breaks using small gRNA as guides. Cas9 has been successfully introduced into Drosophila for genome editing. Here, we improve the versatility of this method by developing a transgenic system that expresses Cas9 in the Drosophila germline. Using this system, we induced inheritable knock-out mutations by injecting only the gRNA into embryos, achieved highly efficient mutagenesis by expressing gRNA from the promoter of a novel non-coding RNA gene, and recovered homologous recombination-based knock-in of a fluorescent marker at a rate of 4.5% by co-injecting gRNA with a circular DNA donor. Copyright © 2014 Xue et al.

VEST: An Aspect-Based Composition Tool for Real-Time Systems

DTIC Science & Technology

2003-01-01

VEST: An Aspect-Based Composition Tool for Real - Time Systems * John A. Stankovic Ruiqing Zhu Ram Poornalingam Chenyang Lu Zhendong Yu Marty Humphrey...Composition Tool for Real - Time Systems 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK...it is obvious that designers of embedded real - time systems face many difficult problems. By working through various product scenarios with avionics

Civil-Military Change in China: Elites, Institutes, and Ideas After the 16th Party Congress

DTIC Science & Technology

2004-09-01

Xiliang, Lang Longxi, Zhou Xupeng, Zhang Hong, Fang Junzhong, Fang Lufeng, Guo Weihu, Zhu Guangzheng, Zhao Heng, Quan Zhixue, Yu Hongtao , Hou Xiaoqin...Deng Hongtao , and Lei Ziyuan, "Vast Numbers of Officers and Men of All Armed Forces and Armed Police Corps Resolutely Support New CPC Central Committee...and Central Military Commission," Jiefangjun bao, November 17, 2002, p. 1. 14. Jiefangjun bao, November 20, 2002. 15. Qian Xiaohu, Xia Hongqing, Han

Dispersion and Reinforcement of Nanotubes in High Temperature Polymers for Ultrahigh Strength and Thermally Conductive Nanocomposites

DTIC Science & Technology

2007-10-03

system lies in the contact resistance which would be discussed later. Figure 49. The surface resistivity of...Shouping Li et al. [62] ZhiMin Dang et al., Appl. Phys. Lett. 2004, 85, 1. [63] B.K. Zhu et al. Composites Science and Technology 2006, 66, 548. [64...Hiroki Ago et al., Phys. Rev. B 2000, 61, 3. [65] Yonglai Yang et al. Nanotechnology 2004, 15, 1545. [66] Xiaofeng Lu, Jiani Zheng, Danming Chao

LIGHT: A Novel Immunotherapy for Primary and Metastatic Prostate Cancer

DTIC Science & Technology

2012-09-01

remains a mystery [16]. Here, we hypothesize an interesting connection between LIGHT and immune escape involving the interactions between LIGHT, HVEM...HVEM [12]. LIGHT is capable of disrupting BTLA-HVEM interaction through competitive binding [18]. Given two possible interactions with HVEM, naïve T... Leishmania donovani</italic> Infection. PLoS Pathog, 2011. 7(10): p. e1002279. 11. Zhu, M. and Y.-X. Fu, The role of core TNF/LIGHT family members

International Symposium on Stratified Flows (4th) Held in Grenoble, France on June 29-July 2, 1994. Volume 2

DTIC Science & Technology

1994-10-10

G . Pawlal4 L. Arm, 11:30 Measuremtents of a turbulent patch in a rotating, 11:30 Constricted flows from the Pacific to the Indian ilnearly stratified...flow through a channel with an low-Reynolds-number convective boundary layer - underwater sill - 157 198 Z. Zhu, 6. A Lawrence G . N. Colemnan, J. H...vortex 12:15 Hydraulic control analysis of an integrated gravity interactions in stably stratified homogeneous current model - 134 turbulence - 246 ( G

Catecholamines in Post-Traumatic Stress Disorder

DTIC Science & Technology

2012-07-01

could lead to memories that are too strong, contributing to the recurrent, intrusive retrieval of the traumatic events that occurs in PTSD. As a...emotionally arousing experiences are typically vivid and persistent. The recurrent, intrusive memories of traumatic events in post-traumatic stress disorder...signaling plays a critical role in the maintenance of waking and in the regulation of REM sleep. J Neurophysiol 92:2071–2082. Ouyang M, Zhang L, Zhu

China Report: Political, Sociological and Military Affairs.

DTIC Science & Technology

1983-03-18

Production Brigade of Guangbao Commune in raising chickens and rabbits in a big way. We must mobilize the commune member house- holds to utilize...The state and the commune, production brigades, and production teams operate fish farms, some of which raise fry . Why not go ahead with raising fish...Wei Xinyi, Huang Yu, Yang Jike, Guo Tixiang, Meng Fulin, Hu Tan, Zhu Nong, Fang Shiliang, Wang Zenong, Pan Ezhang, Liu Zhengwen, Chen Tianren, Ma

N-Acetyltransferase 1 Polymorphism and Breast Cancer Risk

DTIC Science & Technology

2011-10-01

reported that cancer risk associated with NAT1*10 is further modulated by exposure to environmental carcinogens found in cigarette smoke, meats cooked...at high temperatures, and the use of hair dye. For example, frequent 7 consumption of red meat in combination with NAT1*10 is associated with an...well- done meat intake, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 8, 233-239. Zhu, Y., and Hein, D.W. (2008). Functional effects of

JPRS Report, East Europe

DTIC Science & Technology

1987-10-19

Committee and head of the committee’s Foreign Affairs Department, and Medgyessy Peter, member of the party Central Commit- tee and head of the...vice-premier, and Zhu Liang, head of the International Liaison Department of the CPC Cen- tral Committee. A formal welcoming ceremony is scheduled...forthcoming party congress he will resign even as head of the Central Advisory Commission, the body consisting of elderly politicians. He would then only

Cancer and Stroma-Targeted Immunotherapy with a Genetically Modified DC Vaccine

DTIC Science & Technology

2011-05-01

targeting the tumor stroma in addition to breast cancer cells may produce the desired increase in antitumor activity of DC vaccines for breast cancer...vaccination inhibits 4T1-neu progression. We investigated whether DC-shA20-FAP- HER2 may induce more potent anti- stroma and anti-tumor immunity with the...the immunosuppressive tumor microenviroment resulting in potent antitumor activity. Zhu W, Zhou X, Rollins L , Rooney CM, Gottschalk S, Song XT

Novel Synthesis of 3D Graphene-CNF Electrode Architectures for Supercapacitor Applications

DTIC Science & Technology

2013-06-01

curves. Specifically, I would like to mention LCDR Chris Daskam, LT Russell Canty, LT Jamie Cook , LT Ashley Maxson, LT Samuel Fromille, and Edwin...systems to store energy for the amplifier to use on demand. Additionally, capacitors are used to supply large pulses of current for pulsed power...stark contrast to values quoted in recent studies: Zhu et al. [56] cite a specific capacitance of microwave exfoliated graphene electrodes of 200 F/g

The road we travel: Māori experience of cancer.

PubMed

Walker, Tai; Signal, Louise; Russell, Marie; Smiler, Kirsten; Tuhiwai-Ruru, Rawiri

2008-08-08

This research explores Maori experiences of cancer. It does so to shed light on the causes of cancer inequalities for Maori. The views of 44 Maori affected by cancer--including patients, survivors, and their whanau (extended families)--were gathered in five hui (focus groups) and eight interviews in the Horowhenua, Manawatu, and Tairawhiti districts of New Zealand. After initial analysis, a feedback hui was held to validate the findings. Maori identified effective providers of cancer services such as Maori health providers. They also identified positive and negative experiences with health professionals. The involvement of whanau in the cancer journey was viewed as highly significant as was a holistic approach to care. Participants had many suggestions for improvements to cancer services such as better resourcing of Maori providers, cultural competence training for all health workers, the use of systems 'navigators', and the inclusion of whanau in the cancer control continuum. The research identifies a range of health system, healthcare process, and patient level factors that contribute to inequalities in cancer for Maori. It also explores the role of racism as a root cause of these inequalities and calls for urgent action.

Evidence for melt partitioning between olivine and orthopyroxene in partially molten harzburgite

NASA Astrophysics Data System (ADS)

Miller, K.; Zhu, W.; Montesi, L. G.; Le Roux, V.; Gaetani, G. A.

2013-12-01

During melting at mid-ocean ridges, melt is driven into an equilibrium, minimum-energy configuration by surface energy gradients between solid-solid and solid-liquid phase boundaries. Such a configuration, where melt is mostly restricted to three and four-grain junctions, acts as a porous medium through which melt can percolate to the surface. For a monomineralic system, melt is distributed evenly among all grains. However, in mineralogical heterogeneous systems, melt partitions unevenly between the various solid phases to minimize the total energy of the system. In a ocean ridge melting environment, where olivine is often juxtaposed against orthopyroxene (opx), lithologic partitioning is expected to turn olivine-rich regions into high-permeability conduits, through which melt can be quickly extracted, drastically increasing the permeability of the mantle [Zhu and Hirth, 2003]. Lithologic partitioning has been demonstrated in experiments using analogue systems [Watson, 1999]; however, to date, no experiment has confirmed its existence in partially molten mantle systems. We present experimental results that determine the degree of melt partitioning between olivine and opx in partially molten harzburgites. Samples were prepared from a powdered mixture of oxides and carbonates and then hot-pressed in a solid-media piston-cylinder apparatus at 1350°C and 1.5GPa [Zhu et al., 2011] to achieve an 82/18 vol. % ratio of olivine to opx. Prior to hot-pressing, basalt was added to the powdered mixtures in various proportions to test for lithologic partitioning across a range of melt fractions. Three-dimensional, 700nm-resolution images of our samples were obtained using synchrotron X-ray microtomography on the 2BM station of the Advanced Photon Source at Argonne National Labs. Image data were filtered using an anisotropic diffusion filter to enhance phase contrast and then segmented to produce binary representations of each phase. In order to quantitatively demonstrate

Enhanced Lesion Visualization in Image-Guided Noninvasive Surgery With Ultrasound Phased Arrays

DTIC Science & Technology

2001-10-25

81, 1995. [4] N. Sanghvi et al., “Noninvasive surgery of prostate tissue by high-intensity focused ultrasound ,” IEEE Trans. UFFC, vol. 43, no. 6, pp...ENHANCED LESION VISUALIZATION IN IMAGE-GUIDED NONINVASIVE SURGERY WITH ULTRASOUND PHASED ARRAYS Hui Yao, Pornchai Phukpattaranont and Emad S. Ebbini...Department of Electrical and Computer Engineering University of Minnesota Minneapolis, MN 55455 Abstract- We describe dual-mode ultrasound phased

Annotated Bibliography of Publications from the US Navy’s Marine Mammal Program, Update. Revision A.

DTIC Science & Technology

1985-07-01

radio tags, and freeze branding. Hui, C. A. 1979 Undersea topography and distribution of dolphins of the genus Delphinus in the Southern California...Delphinapterus leucas. Sleep Research 3:85 (Abstract). Observed behavior consisted of active waking, quiet waking, and stereotypic circular swimming. The...behavior consisted of periods of unambiguous waking, stereotypic circular swimming with brief (20-30 sec) eye closure and other indications of sleep

Two new species of Oxycera (Diptera, Stratiomyidae) from Ningxia, China

PubMed Central

Zai-Hua, Yang; Jin-Yong, Yu; Mao-Fa, Yang

2012-01-01

Abstract Two new speices, Oxycera rozkosnyi sp. n. and Oxycera ningxiaensis sp. n., are described from Liupanshan Nature Reserve, Ningxia Hui Autonomous Region, Northwest China. All essential diagnostic characters are figured and possible relationships of both taxa are briefly discussed, and a new key to species of Oxycera from China. The type specimens are deposited in the Institute of Entomology, Guizhou University, Guiyang (GUGC). PMID:22707906

The health and quality of life outcomes among youth and young adults with cerebral palsy.

PubMed

Young, Nancy L; Rochon, Trista G; McCormick, Anna; Law, Mary; Wedge, John H; Fehlings, Darcy

2010-01-01

Young NL, Rochon TG, McCormick A, Law M, Wedge JH, Fehlings D. The health and quality of life outcomes among youth and young adults with cerebral palsy. To describe the health and quality of life (QoL) of youth and young adults who have cerebral palsy (CP), and to assess the impact of 3 key factors (severity, age, and sex) on these outcomes. Cross-sectional survey. Participants were identified from 6 children's treatment centers in Ontario. The sample of participants (N=199) included youth (n=129; age, 13-17y) and adults (n=70; age, 23-33y) with a broad range of severity: 35% mild, 19% moderate, and 47% severe. Not applicable. Health Utilities Index (HUI(3)), Assessment of Quality of Life (AQoL), and Self-Rated Health (SRH). SRH was reported to be excellent or very good by 57% of youth and 46% of adults. Mean HUI(3) scores were .30 for youth and .31 for adults. Mean AQoL scores were .28 for youth and adults. Severity of CP in childhood predicted 55% of the variance in HUI(3) scores and 45% of the variance in AQoL scores. Age and sex were not significant predictors of health or QoL. The observed health and QoL scores were much lower than those previously reported in the literature. This is likely a result of the inclusion of those with severe CP. The scores for youth were similar to those for adults and suggest that health and QoL outcomes were relatively stable across the transition to adulthood. Youth and adults with CP have limited health status and will require health care support throughout their lives to help them optimize their well being. Longitudinal follow-up studies are essential to understand better the patterns of health in this population over time. Copyright (c) 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

ZZ-Type a posteriori error estimators for adaptive boundary element methods on a curve☆

PubMed Central

Feischl, Michael; Führer, Thomas; Karkulik, Michael; Praetorius, Dirk

2014-01-01

In the context of the adaptive finite element method (FEM), ZZ-error estimators named after Zienkiewicz and Zhu (1987) [52] are mathematically well-established and widely used in practice. In this work, we propose and analyze ZZ-type error estimators for the adaptive boundary element method (BEM). We consider weakly singular and hyper-singular integral equations and prove, in particular, convergence of the related adaptive mesh-refining algorithms. Throughout, the theoretical findings are underlined by numerical experiments. PMID:24748725

Characterization of RACK7 as a Novel Factor Involved in BRCA1 Mutation Mediated Breast Cancer

DTIC Science & Technology

2012-10-01

Characterization of RACK7 as a Novel Factor Involved in BRCA1 Mutation Mediated Breast Cancer Inder Verma, Quan Zhu, Martin Preyer, and Amy Rommel Salk...samples from 5 more human BRCA1 mutant tumors. We continue to collect more human BRCA1-mutant tumors from Dr. Petra Nederlof at the Netherland Cancer...damage pathway. Abstract: "The Novel Zinc-finger Protein ZMYND8 Is Involved in the Stabilization of Stalled Replication Forks", Martin Preyer and

Toward Development of a Field-Deployable Imaging Device for TBI

DTIC Science & Technology

2015-06-01

proportional to the Young modulus with the following relationship: E = 3ρc2, where E is the Young modulus (kilopascals), a measure of the resistance of...Fang M, Jiang WQ, Zhu GF, Zeng HK. Effect of hydroxyethyl starch on intracranial pressure and plasma colloid osmotic pressure in rats with cerebral...creates images of Young’s Modulus, a measure of 81 the resistance to such that larger values describe stiffer tissue. Therefore, maps of Young’s 82

The Effect of Recombinant Human MG53 Protein on Tourniquet-induced Ischemia Reperfusion Injury in Rat Muscle

DTIC Science & Technology

2014-06-01

blind to the treatment , and the prevalence of damaged fibers was quantitated from 10 10x images from each muscle . Approximately 800 fibers were counted...therapeutic cell membrane repair in treatment of muscular dystrophy . Sci Transl Med. 2012; 4(139):139ra185. 11. Weisleder N, Lin P, Zhao X, Orange M, Zhu H...The effect of recombinant human MG53 protein on tourniquet- induced ischemia reperfusion injury in rat muscle Benjamin T. Corona, Ph.D.1, Koyal Garg

International Conference on Langmuir-Blodgett Films (5th) Held in Paris, France on 26-30 August 1991, Abstracts Booklet

DTIC Science & Technology

1991-08-01

Fojihh LN.. aIsetiki, LA. Bazaheu*o, .Kaimx BP30 CI Photo-amplified stroget n y with Incorporation of non-amphiphilic compounds polyion complexed p...donor- films of N-acyl-p-nitroaniline and its acceptor organic compounds homologous amphiphile D. Zhu, C. Yang, Yu. Liu, Y. Xu Y..Mixamo, K, Kauiu, T...R. Kenn, H. MChwald, K. Kjaer, J. LB films of polyheterocyclic compounds with Als-Nielsen long alkyl chains HLNAkabam K. Fukuda, M. Ikeda, K

The Role of Skp2 in the Prostate Tumorigenesis Following Rb and p53 Loss

DTIC Science & Technology

2015-12-01

Developmental and Molecular Biology Room 521 Ullmann 1300 Morris Park Avenue Bronx, NY 10461-1975 AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER rt...t f l t l Molecular Biology Room 521 Ullmann 1300 Morris Park Avenue Bronx, NY 10461-1975 9. SPONSORING / MONITORING AGENCY NAME(S) AND...1300 Morris Park Ave., Room U-521, Bronx, NY 10461. Tel.: 718-430-3320; Fax: 718-430- 8975; E-mail: liang.zhu@einstein.yu.edu. 2 The abbreviations used

Immunologic Intervention in HIV Infection: Anti-Polymerase Responses and Hormonal Regulation.

DTIC Science & Technology

1992-05-01

34), has serious physical ad psyhdologic cosequn , including further compromise of irmmu status in AIMS (1). Dr. D. Kotler of Columbia University recently...nutritional factors in the induction of immunologic abnormalities in HIV-positive homosexual men. J. AIDS 2:235, 1989. 2. Kotler D, Nutrition in AIDS...1051, 1990. 14. Korq X-B, Zhu Q-Y, Vidal PM, Watanole AM, Polsky B, Armstrong D, Ostrandz M, lang SA Jr, Rxthors E, Cmaa T-C. Cmparisons of anti-HIV

Seismic Observations and Interpretation in NE China, Infrasound Observations and Interpretation in Utah

DTIC Science & Technology

2010-07-30

from Xu et al., 2005). (b) Map of SMU-IGPCEA Huailai Seismic Network and seismicity ( open circles) for the time period of January 01, 2002 through...the Beijing-Huailai-Fengzhen (H20) refraction/ wide angle reflection profile (Zhu et al., 1997). Open circles are locations of two historical...historycatalog_query.jsp) and the China Seismograph Network ( CSN ) Catalog (http://210.72.96.165/wdcd/csn_catalog_p001.jsp) list a total of 323 earthquakes with magnitude

China Report, Political, Sociological and Military Affairs, No. 418.

DTIC Science & Technology

1983-05-09

the United States on the ground that they are either premature or too costly. Last month, the U.S. Justice Department labelled three Canadian films ...as "political propaganda" and restricted their showing in the United States. Two of the films dealt with the environmental hazards posed by the acid...most important. Without the needs of the times, there will be no reportage. This explains why Zhu Ziqing, the author of " Moonlight by the Lotus

JPRS Report, China, Red Flag, Number 6, 16 March 1988

DTIC Science & Technology

1988-05-26

as published] It Is Necessary To Seriously Implement the Principle of Democracy in Work Concerning Cadres [Zhu YanJ T^""\\’- 7T""^ I \\ Increase ...persist in taking the mass line, to carry forward socialist democracy, to increase the degree of opening up, and to enable the masses inside and...34disclose the whole inside story." Increase Enterprises’ Internal Driving Force of Paying Attention to Variety and Quality 40050207b Beijing HONGQI

JPRS Report, Science & Technology, China: Energy.

DTIC Science & Technology

1992-02-26

China Becomes Major Energy Player [Wang Hanlin; KEJIRIBAO, 19Aug91] 1 S&T Led the Way to Creating Energy Bases [ Lu Xinning; RENMIN RIBAO, 16 Sep 91...RIBAO, 14 Dec 91] 18 COAL Energy Ministry Takes Steps To Strengthen Coal Industry [Xie Ranhao; JINGJI RIBAO, 29 Oct 91] .... 19 Henan’s Coal...27 Dec 91] 22 Zhongyuan Is Tempting Target for Oil and Gas Theft [ Zhu Sixiong; RENMIN RIBAO, 17 Dec 91] 23 Big Breakthrough in Prospecting

Statistical and Variational Methods for Problems in Visual Control

DTIC Science & Technology

2009-03-02

plane curves to round points," /. Differential Geometry 26 (1987), pp. 285-314. 12 [7] S. Haker , G. Sapiro, and A. Tannenbaum, "Knowledge-based...segmentation of SAR data with learned priors," IEEE Trans. Image Processing, vol. 9, pp. 298-302, 2000. [8] S. Haker , L. Zhu, S. Angenent, and A...Tannenbaum, "Optimal mass transport for registration and warping" Int. Journal Computer Vision, vol. 60, pp. 225-240, 2004. [9] S. Haker , G. Sapiro, A

Geometric Variational Methods for Controlled Active Vision

DTIC Science & Technology

2006-08-01

Haker , L. Zhu, and A. Tannenbaum, ``Optimal mass transport for registration and warping’’ Int. Journal Computer Vision, volume 60, 2004, pp. 225-240. G...pp. 119-142. A. Angenent, S. Haker , and A. Tannenbaum, ``Minimizing flows for the Monge-Kantorovich problem,’’ SIAM J. Math. Analysis, volume 35...Shape analysis of structures using spherical wavelets’’ (with S. Haker and D. Nain), Proceeedings of MICCAI, 2005. ``Affine surface evolution for 3D

Area-Preserving Mappings for the Visualization of Medical Structures

DTIC Science & Technology

2003-01-01

Women’s Hospital, Harvard Medical School, Boston, MA 02115 haker @bwh.harvard.edu Abstract. In this note, we present a method for flattening anatomi- cal... Haker , and A. Tannenbaum pronounced when we wish to construct a flattened representation for a multi- branched surface. Here we take another approach...convex function w, i.e., ũ = ∇w. 280 L. Zhu, S. Haker , and A. Tannenbaum 3.2 Finding the Minimizer There have been many approaches for finding the

Chemistry and Physics of Analyte Identification in Integrated Nanosensors

DTIC Science & Technology

2009-02-05

points," / Differential Geometry 26 (1987), pp. 285-314. 12 [7] S. Haker , G. Sapiro, and A. Tannenbaum, "Knowledge-based segmentation of SAR data with...learned priors," IEEE Trans. Image Processing, vol. 9, pp. 298-302, 2000. [8] S. Haker , L. Zhu, S. Angenent, and A. Tannenbaum, "Optimal mass...transport for registration and warping" Int. Journal Computer Vision, vol. 60, pp. 225-240, 2004. [9] S. Haker , G. Sapiro, A. Tannenbaum, and D. Washburn

High Frequency Bottom Interaction in Range Dependent Biot Media

DTIC Science & Technology

1999-09-30

acoust . Soc. Am. Stephen, R.A. Benchmark models for propagation and scattering in Biot media. Fall ASA, Norfolk, VA, October...1998, J. Acoust . Soc. Am., 104, 1808. X. Zhu and G. A. McMechan, “Numerical simulation of seismic responses of poroelastic reservoirs using Biot...reverberation from rough and heterogeneous seafloors. J. acoust . Soc. Am. Stephen, R.A., in press. Optimum and standard beam widths for numerical modeling of interface scattering problems. J. acoust . Soc. Am.

China Report, Political, Sociological and Military Affairs

DTIC Science & Technology

1985-03-04

The first 80 chapters of the book were written by Cao Queqln (1716-1763H a member of a once influential and prosperous Manchurian noble family in what...is now Nanjing, Jiangsu Province. The family was doomed to total bankruptcy by the emperor in the course of intricate power struggles. Cao , who...Li Yuhua , Wu Zhichuan, Zhu Zuxiang, Yu Jiyi, and Xing Zitao, vice chairmen of the provincial people’s congress Standing Committee, attended. Li

The Role of Networks in Cloud Computing

NASA Astrophysics Data System (ADS)

Lin, Geng; Devine, Mac

The confluence of technology advancements and business developments in Broadband Internet, Web services, computing systems, and application software over the past decade has created a perfect storm for cloud computing. The "cloud model" of delivering and consuming IT functions as services is poised to fundamentally transform the IT industry and rebalance the inter-relationships among end users, enterprise IT, software companies, and the service providers in the IT ecosystem (Armbrust et al., 2009; Lin, Fu, Zhu, & Dasmalchi, 2009).

From Mao toward Modernity: The Increasing Westernization of the People’s Liberation Army

DTIC Science & Technology

2014-05-22

42Xiaoping Deng and Zhongguo gong chan dang. Zhong yang Makesi En’gesi Liening Sidalin zhu zuo bian yi ju., Selected Works of Deng Xiaoping, 1982...1992. vol. 3, 1st ed. ( Beijing , China: Foreign Languages Press, 1994), 133. 43Information Office of the State Council, The People’s Republic of China...its sovereign interests in what Beijing considered its backyard. The result was Beijing’s adoption of a strategy that sought to compel greater

Water channel experiments of a novel fully-passive flapping-foil turbine

NASA Astrophysics Data System (ADS)

Boudreau, Matthieu; Dumas, Guy; Rahimpour, Mostafa; Oshkai, Peter

2016-11-01

Experiments have been conducted to assess the performances of a fully-passive flapping-foil hydrokinetic turbine for which the blade's motions are stemming from the interaction between the blade's elastic supports (springs and dampers) and the flow field. Previous numerical studies conducted by Peng & Zhu (2009) and Zhu (2012) have proved that a simplified version of such a turbine can extract a substantial amount of energy from the flow while offering the potential to greatly simplify the complex mechanical apparatus needed to constrain and link the blade's pitching and heaving motions in the case of the more classical flapping-foil turbine (e.g., Kinsey et al., 2011). Based on the promising numerical investigations of Veilleux (2014) and Veilleux & Dumas (2016), who proposed a more general version of this novel concept, a prototype has been built and tested in a water channel at a chord Reynolds number of 17,000. Periodic motions of large amplitudes have been observed leading to interesting energy harvesting efficiencies reaching 25% for some specific sets of structural parameters. The sensitivity of the turbine's dynamics to each of the seven structural parameters appearing in the equations of motion has been experimentally evaluated around a case close to the optimal one. Financial support from the Natural Sciences and Engineering Research Council of Canada (NSERC) is gratefully acknowledged by the authors.

The Electronic Behavior of Zinc-Finger Protein Binding Sites in the Context of the DNA Extended Ladder Model

NASA Astrophysics Data System (ADS)

Oiwa, Nestor; Cordeiro, Claudette; Heermann, Dieter

2016-05-01

Instead of ATCG letter alignments, typically used in bioinformatics, we propose a new alignment method using the probability distribution function of the bottom of the occupied molecular orbital (BOMO), highest occupied molecular orbital (HOMO) and lowest unoccupied orbital (LUMO). We apply the technique to transcription factors with Cys2His2 zinc fingers. These transcription factors search for binding sites, probing for the electronic patterns at the minor and major DNA groves. The eukaryotic Cys2His2 zinc finger proteins bind to DNA ubiquitously at highly conserved domains. They are responsible for gene regulation and the spatial organization of DNA. To study and understand these zinc finger DNA-protein interactions, we use the extended ladder in the DNA model proposed by Zhu, Rasmussen, Balatsky & Bishop (2007) te{Zhu-2007}. Considering one single spinless electron in each nucleotide π-orbital along a double DNA chain (dDNA), we find a typical pattern for the bottom of BOMO, HOMO and LUMO along the binding sites. We specifically looked at two members of zinc finger protein family: specificity protein 1 (SP1) and early grown response 1 transcription factors (EGR1). When the valence band is filled, we find electrons in the purines along the nucleotide sequence, compatible with the electric charges of the binding amino acids in SP1 and EGR1 zinc finger.

Controlling Self-Assembly in Al(110) Homoepitaxy

NASA Astrophysics Data System (ADS)

Tiwary, Yogesh; Fichthorn, Kristen

2010-03-01

Homoepitaxial growth on Al(110) exhibits nanoscale self-assembly into huts with well-defined (100) and (111) facets [1]. Although some of the diffusion mechanisms underlying this kinetic self-assembly were identified and incorporated into a two-dimensional model [2], we used density-functional theory (DFT) to identify many other mechanisms that are needed to describe the three-dimensional assembly seen experimentally [3]. We developed a three-dimensional kinetic Monte Carlo (KMC) model of Al(110) homoepitaxy. The inputs to the model were obtained from DFT [3,4]. Our model is in agreement with experimentally observed trends for this system. We used KMC to predict self-assembly under various growth conditions. To achieve precise placement of Al nanohuts, we simulated thermal-field-directed assembly [5]. Our results indicate that this technique can be used to create uniform arrays of nanostructures. [1] F. Buatier de Mongeot, W. Zhu, A. Molle, R. Buzio, C. Boragno, U. Valbusa, E. Wang, and Z. Zhang, Phys. Rev. Lett. 91, 016102 (2003). [2] W. Zhu, F. Buatier de Mongeot, U. Valbusa, E. G. Wang, and Z. Y. Zhang, Phys. Rev. Lett. 92, 106102 (2004). [3] Y. Tiwary and K. A. Fichthorn, submitted to Phys. Rev. B. [4] Y. Tiwary and K. A. Fichthorn, Phys. Rev. B 78, 205418 (2008). [5] C. Zhang and R. Kalyanaraman, Appl. Phys. Lett. 83, 4827 (2003).

Measurement of the parity-violating asymmetry in inclusive electroproduction of π - near the Delta 0 resonance

DOE PAGES

Androic, D.; Armstrong, D. S.; Bailey, S. L.; ...

2012-03-20

The parity-violating (PV) asymmetry of inclusive π - production in electron scattering from a liquid deuterium target was measured at backward angles. The measurement was conducted as a part of the G0 experiment, at a beam energy of 360 MeV. The physics process dominating pion production for these kinematics is quasi-free photoproduction off the neutron via the Δ 0 resonance. In the context of heavy-baryon chiral perturbation theory (HBχPT), this asymmetry is related to a low energy constant d Δ - that characterizes the parity-violating γNΔ coupling. Zhu et al. calculated d Δ - in a model benchmarked by themore » large asymmetries seen in hyperon weak radiative decays, and predicted potentially large asymmetries for this process, ranging from A γ - = -5.2 to +5.2 ppm. The measurement performed in this work leads to A γ - = -0.36 ± 1.06 ± 0.37 ± 0.03 ppm (where sources of statistical, systematic and theoretical uncertainties are included), which would disfavor enchancements considered by Zhu et al. proportional to V ud/V us. The measurement is part of a program of inelastic scattering measurements that were conducted by the G0 experiment, seeking to determine the N-Δ axial transition form-factors using PV electron scattering.« less

Translations from Red Flag, Number 10, 8 Oct 1977

DTIC Science & Technology

1977-12-01

of Kwangtung. While in Kwangtung we placed emphasis on visiting the four counties of Nan-hai, Hsin -hui, Shun-te and Hua, seven communes and other...960-channel microwave communications equipment of an advanced modern technical level were both successfully manufactured and put into operation, and ...trunk lines have been set up. Yen -shou County, the Mou-tan-chiang District and other municipalities and counties have basically achieved the four

Characterizing and Targeting Replication Stress Response Defects in Breast Cancer

DTIC Science & Technology

2015-08-01

1 AD_________________ Award Number: W81XWH-10-1-0558 TITLE: Characterizing and Targeting Replication Stress Response Defects in Breast Cancer ...PRINCIPAL INVESTIGATOR: Shiaw-Yih Lin, Ph.D. CONTRACTING ORGANIZATION: University of Texas M. D. Anderson Cancer Center Houston, TX 77030 REPORT...Response Defects in Breast Cancer 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Betty Diamond 5d. PROJECT NUMBER Chun-Jen Lin, Hui Dai

Luminescence Measurements of Xe+ + N2 and Xe2+ + N2 Hyperthermal Charge Transfer Collisions (Postprint)

DTIC Science & Technology

2012-04-10

HYPERTHERMAL CHARGE TRANSFER COLLISIONS (POSTPRINT) 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR( S ) 5d. PROJECT NUMBER...2301 Benjamin D. Prince and Yu-Hui Chiu 5e. TASK NUMBER PPM00004270 5f. WORK UNIT NUMBER EF004373 7. PERFORMING ORGANIZATION NAME( S ...Kirtland AFB, NM 87117-5776 AFRL-RV-PS-TR-2012-0093 9. SPONSORING / MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR

JPRS Report, East Asia, Korea: Kulloja, No. 1, January 1988

DTIC Science & Technology

1989-01-31

sweatshop society, the popular masses were not able to become independent social and political organic bodies because they were divided, without being...translated] 1 Let Us Vigorously Launch a March-Forward Movement To Achieve the Complete Victory of Socialism [Editorial] 1 The Leader Is the Brain of...Victory of Socialism [So Kwan-hui] 25 The Development of Science and Technology and a Wholesale Technological Remodeling of the People’s Economy

Multilevel Preconditioners for Reaction-Diffusion Problems with Discontinuous Coefficients

DOE PAGES

Kolev, Tzanio V.; Xu, Jinchao; Zhu, Yunrong

2015-08-23

In this study, we extend some of the multilevel convergence results obtained by Xu and Zhu, to the case of second order linear reaction-diffusion equations. Specifically, we consider the multilevel preconditioners for solving the linear systems arising from the linear finite element approximation of the problem, where both diffusion and reaction coefficients are piecewise-constant functions. We discuss in detail the influence of both the discontinuous reaction and diffusion coefficients to the performance of the classical BPX and multigrid V-cycle preconditioner.

Quantum 1/f Noise in Solid State Devices in Particular Hg(1-x)Cd(x)Te N(+)-P Diodes

DTIC Science & Technology

1989-05-15

1 / f noise in pentodes. 3. A. van der Ziel, P. H. Handel, X. C. Zhu, and K. H. Duh, "A theory of the Hooge parameters of solid-state...the progress reports 12. P. H. Hardel and A. van der Ziel, "Relativistic correction of the Hooge parameter for Umklapp 1 / f noise ," Physica, vol. 141B... Hooge parameter and of fundamental 1 / f noise sources. As a side result many quantum 1 / f noise formulas are verified

Large deformation frictional contact analysis with immersed boundary method

NASA Astrophysics Data System (ADS)

Navarro-Jiménez, José Manuel; Tur, Manuel; Albelda, José; Ródenas, Juan José

2018-01-01

This paper proposes a method of solving 3D large deformation frictional contact problems with the Cartesian Grid Finite Element Method. A stabilized augmented Lagrangian contact formulation is developed using a smooth stress field as stabilizing term, calculated by Zienckiewicz and Zhu Superconvergent Patch Recovery. The parametric definition of the CAD surfaces (usually NURBS) is considered in the definition of the contact kinematics in order to obtain an enhanced measure of the contact gap. The numerical examples show the performance of the method.

Symposium KK: Structure-Property Relationships in Biomineralized and Bio-mimetic Composites

DTIC Science & Technology

2010-04-06

Preventive and Restorative Dental Sciences, UCSF, San Francisco, California. 4:45 PM KK2.8 Damage and Crack Evolution in Mammalian Enamel James Jin...Technology, Graz, Austria. 9:45AMKK6.S AFM and PFM measurements of Enamel in order to Determine the Crack Tip Toughness and Cohesive Zone of Enamel Gerold...11:00 AM KK9.7 Enamel Matrix Guided Growth of Apatite Vuk Uskokovic1. Li Zhu2, Wu Li2 and Stefan Habelitz1; ’Department of Preventive and

Development of Nanostructure Materials and Architecture for High Performance Li-rechargeable Batteries with Ultrafast Charge Rate

DTIC Science & Technology

2011-04-22

overcome these difficulties extensive work has been done. Surface coatings with ZnO , SiO2, and Bi2O3 have been proposed to enhance stability of electrodes...Liu, G. Q.; Wen, L.; Liu, Y. M. Journal of Solid State Electrochemistry 2010, 14, 2191. (23) Myung, S. T.; Komaba, S.; Kumagai, N.; Yashiro, H.; Chung...Y. R.; Shu, J.; Zhu, R. S. Journal of Solid State Electrochemistry 2009, 13, 913. (29) Aklalouch, M.; Amarilla, J. M.; Rojas, R. M.; Saadoune, I

JPRS Report, Science & Technology China

DTIC Science & Technology

1989-02-23

Protoplast Culture of Rice (Oryza sativa L.), Plant Regeneration From Protoplast-Derived Calli 40091011a Beijing YICHUAN XUEBAO [ACTA GENETICA ...YICHUAN XUEBAO [ACTA GENETICA SINICA] in Chinese Vol 15 No 5, Oct 88 pp 329-334 [English abstract of article by Tao Zirong [7118 5261 2837], et al...Chang, et al., ACTA GENETICA SINICA, Vol 7 No 3, 1980 pp 283-288. 7. Zhu Zhongchun, et al., ACTA GENETICA SINICA, Vol 8 No 1, 1981 pp 63-65, 8. Mix, G

Growth of High Quality Carbon Nanotubes on Free Standing Diamond Substrates

DTIC Science & Technology

2010-01-01

CNTs forming a mat of ~5 µm thickness and consisting of ~20 nm diameter tubes were observed to grow in a thermal CVD system using C2H2 as precursor...with CNT microfin architectures have been recently proposed by Kordas et al. [5]. CNT films as thermal interface materials were also discussed by Zhu...using a 1 inch diameter quartz tube in a horizontal furnace. Initially, the tube furnace was evacuated by using a rough pump and then purged with Ar

Habitat Variability and Ethnic Diversity in Northern Tibetan Plateau.

PubMed

Jia, Xin; Lee, Harry F; Cui, Mengchun; Liu, Chao; Zeng, Lin; Yue, Ricci P H; Zhao, Yang; Lu, Huayu

2017-04-20

There are 56 officially-recognized ethnic groups in China. However, the distinct geographic patterns of various ethnic groups in relation to the physical environment in China have rarely been investigated. Based on the geo-referenced physical environmental parameters of 455 Han, Tu, Hui, Salar, Mongolian, and Tibetan communities in Qinghai, we found that the communities could be statistically demarcated by temperature and aridity threshold according to their ethnicity, implying that the geographic distribution of each ethnic group is mediated by the physical environment. We also observed that the habitat of each ethnic group is ecologically compatible with current subsistence strategies. Tibetans settle in cold and humid high-altitude regions owing to the cultivation of highland barley and the breeding of yak, dzo, Tibetan sheep and Tibetan goat. Mongolians survive by animal husbandry in cold and dry grassland areas. Han and Tu people settle in the Huangshui River Valley, which offers relatively humid climate and flat land for agriculture. Hui and Salar people occupy the Yellow River Valley with its relatively arid environment and grassland vegetation suitable for animal breeding. Our findings offer a new perspective in explaining the geographic patterns and the varieties of ethnic groups in China and elsewhere.

Habitat Variability and Ethnic Diversity in Northern Tibetan Plateau

NASA Astrophysics Data System (ADS)

Jia, Xin; Lee, Harry F.; Cui, Mengchun; Liu, Chao; Zeng, Lin; Yue, Ricci P. H.; Zhao, Yang; Lu, Huayu

2017-04-01

There are 56 officially-recognized ethnic groups in China. However, the distinct geographic patterns of various ethnic groups in relation to the physical environment in China have rarely been investigated. Based on the geo-referenced physical environmental parameters of 455 Han, Tu, Hui, Salar, Mongolian, and Tibetan communities in Qinghai, we found that the communities could be statistically demarcated by temperature and aridity threshold according to their ethnic populations, implying that the geographic distribution of each ethnic group is mediated by the physical environment. We also observed that the habitat of each ethnic group is ecologically compatible with current subsistence strategies. Tibetans settle in cold high-altitude regions owing to the cultivation of highland barley and the breeding of yak, dzo, Tibetan sheep and Tibetan goat. Mongolians survive by animal husbandry in cold and humid grassland areas. The Han and Tu ethnic groups settle in the Huangshui River Valley, which offers relatively humid climate and flat land for agriculture. The Hui and Salar ethnic groups occupy the Yellow River Valley with its relatively arid environment and grassland vegetation suitable for animal breeding. Our findings offer a new perspective in explaining the geographic pattern and the variety of ethnic groups in China and elsewhere.

Work fluctuations for a Brownian particle between two thermostats

NASA Astrophysics Data System (ADS)

Visco, Paolo

2006-06-01

We explicitly determine the large deviation function of the energy flow of a Brownian particle coupled to two heat baths at different temperatures. This toy model, initially introduced by Derrida and Brunet (2005, Einstein aujourd'hui (Les Ulis: EDP Sciences)), not only allows us to sort out the influence of initial conditions on large deviation functions but also allows us to pinpoint various restrictions bearing upon the range of validity of the Fluctuation Relation.

Geoffrey Burbidge : L'art de la critique

NASA Astrophysics Data System (ADS)

Bonnet-Bidaud, J. M.

1997-06-01

Avec pres de cinquante ans de carriere derriere lui, Geoffrey Burbidge n'a rien perdu de son gout du débat et de la controverse. Mondialement reconnu pour ses travaux sur les quasars, il en agace aujourd'hui plus d'un en venant deranger le bel ordonnancement de la cosmologie. Il porte sur le monde scientifique un regard tres critique, condamnant notamment ces chercheurs qui acceptent trop volontiers d'emprunter les chemins tout traces.

Armed Forces and National Development in Korea

DTIC Science & Technology

1988-12-01

2698 Naval Postgraduate School Monterey, CA 93943 7. Ha, Tae Hwan SMC 2588 Naval Postgraduate School Monterey, CA 93943 8. Kim , Dong Hui SMC 2610 Naval...an agreement between the Provisional Government leader Kim Ku and Chiang Kai-Shek. Many of these Korean officers, mostly the Japanese-trained, played...when the military took over the corrupt and inefficient government [Ref. 6:p. 36]. Kim said that the military assumption of power in 1961 was

Biochemical Markers for Exposure to Low Doses of Organophosphorus Insecticides

DTIC Science & Technology

2005-08-01

Rodriguez OP, Muth GW, Berkman CE, Kim K and Thompson CM (1997) Inhibition of various cholinesterases with the enantiomers of malaoxon. Bull Environ Contain...including diazepam (Fehskc et aL., phylated human butyrylcholinesterase. Chem. Res. Toxicol. 15, 582-590. 1979; Peters, 1996) and ibuprofen , bind to the...dose of diazepam or ibuprofen . Or conver- Hui, D. M., and Minami, M. (2000). Monitoring of fluorine in urine samples ofpatients involved in the Tokyo

The Longitudinal Health Study: A Multiphasic Medical Surveillance Program for U. S. Navy Submarine and Diving Personnel

DTIC Science & Technology

1974-05-31

olecranon (triceps), (2) at the infer- ior tip of the scapula (subscapular), and (3) at the right midaxillary line at the level of the umbilicus...reliable character- ization of color vision patterns. " The Pseudo-Isochromic Plates provide a quick screening device. The more sen- sitive...Isochromatic Plates Famsworth 100 - Hue Test Hecht - Schlaer Anomaloscope 13 MKNSWOtTH-MUNSfU IOO-HUI T«T ft Calef Viti«n MUNSIU COLO« COMPANT

China Report, Political, Sociological and Military Affairs

DTIC Science & Technology

1985-02-05

away long ago. However, their in- domitable spirit and their spirit of heroic struggle are still fresh in my memory. At that time, Cao Rui, the... Cao Rui were compelled to solve the problem through legal means by transferring the representatives in custody to the Hebei Provincial Court of...Zhang Ming, Tang Shudi, Want Zibo, Wang Jingmin, Li Baoqi. Wei Jinshan, and Chen Hui: advisers of the military region Sun Keji, Zhang Yuhua , and Wu

Targeting Signal Transducers and Activators of Transcription-3 (Stat3) As a Novel Strategy In Sensitizing Breast Cancer To Egfr-Targeted Therapy

DTIC Science & Technology

2008-06-01

Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and...Novel Strategy In Sensitizing Breast Cancer To Egfr-Targeted Therapy 5b. GRANT NUMBER W81XWH-07-1-0390 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ...Hui-Wen Lo, Ph.D. 5d. PROJECT NUMBER 5e. TASK NUMBER Email: huiwen.lo@duke.edu 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S

Third Supplement to ’A Catalog of the Mosquitoes of the World’ (Diptera: Culicidae)

DTIC Science & Technology

1992-11-01

Type loc.: Jabilla. Quesedas del Medio . Apure State. Venezuela (holotype 6: DERM). isabelae Duret Harbach et a!. 1991:194 (holotype 6: change A to USNM...de Venezuela. Bol. Dir. Ma- Morphological and genetic characteriza- laniol. Saneam. Ambient . 27:94-104. A tion of the Aedes (Och/croiatius) commuflis...Fam- in]" (Diptera: Culicidae) por medio de tar- ily Culicidae. pp. 191-218. In: N.L. Even- jetas perforadas. Physis (B. Aires) 17:535- huis (ed

Reply to ``Comment II on `Quantum secret sharing based on reusable Greenberger-Horne-Zeilinger states as secure carriers' ''

NASA Astrophysics Data System (ADS)

Karimipour, V.

2006-07-01

In the preceding Comment [Jian-Zhong Du, Su-Juan Qin, Qiao-Yan Wen, and Fu-Chen Zhu, Phys. Rev. A 74, 016301 (2006)], it has been shown that in a quantum secret sharing protocol proposed in [S. Bagherinezhad and V. Karimipour, Phys. Rev. A 67, 044302 (2003)], one of the receivers can cheat by splitting the entanglement of the carrier and intercepting the secret, without being detected. In this reply we show that a simple modification of the protocol prevents the receivers from this kind of cheating.

Optimal control of population and coherence in three-level Λ systems

NASA Astrophysics Data System (ADS)

Kumar, Praveen; Malinovskaya, Svetlana A.; Malinovsky, Vladimir S.

2011-08-01

Optimal control theory (OCT) implementations for an efficient population transfer and creation of maximum coherence in a three-level system are considered. We demonstrate that the half-stimulated Raman adiabatic passage scheme for creation of the maximum Raman coherence is the optimal solution according to the OCT. We also present a comparative study of several implementations of OCT applied to the complete population transfer and creation of the maximum coherence. Performance of the conjugate gradient method, the Zhu-Rabitz method and the Krotov method has been analysed.

The Contribution of Prohibitin 1 to Prostate Cancer Chemoresistance

DTIC Science & Technology

2015-10-01

ceramide-PEG5K in normal BALB/c mice after i.v. injection. The siRNA was labeled with near infrared (NIR) dye DY647. (B) Ex vivo fluorescence image of...ceramide-PEG5K (Right) siRNA NPs at 18 h. The siRNA was labeled with dye DY547. (Scale bar, 10 μm.) Zhu et al. PNAS | June 23, 2015 | vol. 112 | no...Woodrow KA, et al. (2009) Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nat Mater

Effects of traditional Chinese patent medicine on essential hypertension: a systematic review.

PubMed

Xiong, Xingjiang; Wang, Pengqian; Zhang, Yuqing; Li, Xiaoke

2015-02-01

that focus on mortality and cardiovascular events during long-term follow-up are warranted before TCPM can be recommended for hypertensive patients. Two TCPMs, Song ling xue mai kang capsules and Yang xue qing nao granules, should be prioritized for further research.

Comparisons of external fixator combined with limited internal fixation and open reduction and internal fixation for Sanders type 2 calcaneal fractures: Finite element analysis and clinical outcome.

PubMed

Pan, M; Chai, L; Xue, F; Ding, L; Tang, G; Lv, B

2017-07-01

The aim of this study was to compare the biomechanical stability and clinical outcome of external fixator combined with limited internal fixation (EFLIF) and open reduction and internal fixation (ORIF) in treating Sanders type 2 calcaneal fractures. Two types of fixation systems were selected for finite element analysis and a dual cohort study. Two fixation systems were simulated to fix the fracture in a finite element model. The relative displacement and stress distribution were analysed and compared. A total of 71 consecutive patients with closed Sanders type 2 calcaneal fractures were enrolled and divided into two groups according to the treatment to which they chose: the EFLIF group and the ORIF group. The radiological and clinical outcomes were evaluated and compared. The relative displacement of the EFLIF was less than that of the plate (0.1363 mm to 0.1808 mm). The highest von Mises stress value on the plate was 33% higher than that on the EFLIF. A normal restoration of the Böhler angle was achieved in both groups. No significant difference was found in the clinical outcome on the American Orthopedic Foot and Ankle Society Ankle Hindfoot Scale, or on the Visual Analogue Scale between the two groups (p > 0.05). Wound complications were more common in those who were treated with ORIF (p = 0.028). Both EFLIF and ORIF systems were tested to 160 N without failure, showing the new construct to be mechanically safe to use. Both EFLIF and ORIF could be effective in treating Sanders type 2 calcaneal fractures. The EFLIF may be superior to ORIF in achieving biomechanical stability and less blood loss, shorter surgical time and hospital stay, and fewer wound complications. Cite this article : M. Pan, L. Chai, F. Xue, L. Ding, G. Tang, B. Lv. Comparisons of external fixator combined with limited internal fixation and open reduction and internal fixation for Sanders type 2 calcaneal fractures: Finite element analysis and clinical outcome. Bone Joint Res 2017

Factors Associated with Adherence to and Treatment Duration of Erlotinib Among Patients with Non-Small Cell Lung Cancer.

PubMed

Hess, Lisa M; Louder, Anthony; Winfree, Katherine; Zhu, Yajun E; Oton, Ana B; Nair, Radhika

2017-06-01

funding from Eli Lilly and Company to Comprehensive Health Insights, a Humana company, as a collaborative research project involving employees of both companies. Hess, Winfree, Zhu, and Oton are employees of Eli Lilly and Company. Louder and Nair are employees of Comprehensive Health Insights, which received funding to complete this research. Study concept and design were contributed by Hess, Zhu, Winfree, and Oton. Nair and Louder collected the data, and data interpretation was performed by all the authors. The manuscript was written primarily by Hess, along with Nair, and revised by Hess, Nair, Louder, and Winfree, with assistance from Zhu and Louder.

Coupled multiphase reactive flow and mineral dissolution-precipitation kinetics: Examples of long-term CO2 sequestration in Utsira Sand, Norway and Mt. Simon Formation, Midwest USA

NASA Astrophysics Data System (ADS)

Zhang, Y.; Zhang, G.; Lu, P.; Hu, B.; Zhu, C.

2017-12-01

The extent of CO2 mineralization after CO2 injection into deep saline aquifers is a result of the complex coupling of multiphase fluid flow, mass transport, and brine-mineral reactions. The effects of dissolution rate laws and groundwater flow on the long-term fate of CO2 have been seriously overlooked. To investigate these effects, we conducted multiphase (CO2 and brine) coupled reactive transport modeling of CO2 storage in two sandy formations (Utsira Sand, Norway1,2 and Mt. Simon formation, USA 3) using ToughReact and simulated a series of scenarios. The results indicated that: (1) Different dissolution rate laws for feldspars can significantly affect the amount of CO2 mineralization. Increased feldspar dissolution will promote CO2 mineral trapping through the coupling between feldspar dissolution and carbonate mineral precipitation at raised pH. The predicted amount of CO2 mineral trapping when using the principle of detailed balancing-based rate law for feldspar dissolution is about twice as much as that when using sigmoidal rate laws in the literature. (2) Mineral trapping is twice as much when regional groundwater flow is taken into consideration in long-term simulations (e.g., 10,000 years) whereas most modeling studies neglected the regional groundwater flow back and effectively simulated a batch reactor process. Under the influence of regional groundwater flow, the fresh brine from upstream continuously dissolves CO2 at the tail of CO2 plume, generating a large acidified area where large amount of CO2 mineralization takes place. The upstream replenishment of groundwater results in ˜22% mineral trapping at year 10,000, compared to ˜4% when this effect is ignored. Refs: 1Zhang, G., Lu, P., Wei, X., Zhu, C. (2016). Impacts of Mineral Reaction Kinetics and Regional Groundwater Flow on Long-Term CO2 Fate at Sleipner. Energy & Fuels, 30(5), 4159-4180. 2Zhu, C., Zhang, G., Lu, P., Meng, L., Ji, X. (2015). Benchmark modeling of the Sleipner CO2 plume

Carbon nanotubes significance in Darcy-Forchheimer flow

NASA Astrophysics Data System (ADS)

Hayat, Tasawar; Rafique, Kiran; Muhammad, Taseer; Alsaedi, Ahmed; Ayub, Muhammad

2018-03-01

The present article examines Darcy-Forchheimer flow of water-based carbon nanotubes. Flow is induced due to a curved stretchable surface. Heat transfer mechanism is analyzed in presence of convective heating process. Xue model of nanofluid is employed to study the characteristics of both single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs). Results for both single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) are achieved and compared. Appropriate transformations correspond to strong nonlinear ordinary differential system. Optimal homotopy analysis method (OHAM) is used for the solution development of the resulting system. The contributions of different sundry variables on the velocity and temperature are studied. Further the skin friction coefficient and local Nusselt number are analyzed graphically for both SWCNTs and MWCNTs cases.

Conditional ablation of Raptor in the male germline causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes.

PubMed

Xiong, Mengneng; Zhu, Zhiping; Tian, Suwen; Zhu, Ruping; Bai, Shun; Fu, Kaiqiang; Davis, James G; Sun, Zheng; Baur, Joseph A; Zheng, Ke; Ye, Lan

2017-09-01

Rapamycin is a clinically important drug that is used in transplantation and cancer therapy but which causes a number of side effects, including male infertility. Its canonical target, mammalian target of rapamycin complex 1 (mTORC1), plays a key role in metabolism and binds chromatin; however, its precise role in the male germline has not been elucidated. Here, we inactivate the core component, Raptor, to show that mTORC1 function is critical for male meiosis and the inactivation of sex chromosomes. Disruption of the Raptor gene impairs chromosomal synapsis and prevents the efficient spreading of silencing factors into the XY chromatin. Accordingly, mRNA for XY-linked genes remains inappropriately expressed in Raptor -deficient mice. Molecularly, the failure to suppress gene expression corresponded with deficiencies in 2 repressive chromatin markers, H3K9 dimethylation and H3K9 trimethylation, in the XY body. Together, these results demonstrate that mTORC1 has an essential role in the meiotic progression and silencing of sex chromosomes in the male germline, which may explain the infertility that has been associated with such inhibitors as rapamycin.-Xiong, M., Zhu, Z., Tian, S., Zhu, R., Bai, S., Fu, K., Davis, J. G., Sun, Z., Baur, J. A., Zheng, K., Ye, L. Conditional ablation of Raptor in the male germline causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes. © FASEB.

Health‐related quality of life and economic burden of vestibular loss in older adults

PubMed Central

Agrawal, Yuri; Semenov, Yevgeniy R.

2017-01-01

Objectives Vestibular loss is a debilitating condition, and despite its high prevalence in older adults, the quality of life (QoL) burden of vestibular loss in older individuals has not been well‐studied. This report quantifies the impact on overall QoL and identifies domains of health most affected. We hypothesize vestibular loss will be associated with impairment in diverse domains of health‐related QoL. Study Design Prospective, case‐control study. Methods A convenience sample of 27 patients age ≥60 years with vestibular physiologic loss was recruited from an academic neurotology clinic. The patients did not have any identifiable cause of their vestibular loss other than aging. The convenience sample was compared to an age‐matched cross‐sectional sample of the general US population (n = 1266). The main outcome was QoL measured by the Ontario Health Utilities Index Mark III (HUI3). Results Compared to the general population, patients with vestibular loss had significantly lower overall unadjusted HUI3 scores (−0.32, p < 0.001). Multivariate regression analysis showed vestibular loss was significantly associated with poorer performance in vision (−0.11 p < 0.0001), speech (−0.15, p < 0.0001), dexterity (−0.13, p < 0.0001), and emotion (−0.07, p = 0.0065). Adjusted aggregate HUI3 was also significantly lower for vestibular loss (−0.15, p = 0.0105). These QoL decrements resulted in an average loss of 1.30 Quality‐Adjusted Life Years (QALYs). When using a $50,000/QALY willingness‐to‐pay threshold, vestibular loss was associated with a $64,929 lifetime economic burden per affected older adult, resulting in a total lifetime societal burden of $227 billion for the US population ≥60 years of age. Conclusions Loss of vestibular function with aging significantly decreases quality of life across multiple domains of well‐being. These QoL reductions are responsible for heavy societal economic burdens of vestibular

Characterization of Novel Genes Within 8P11-12 Amplicon in Breast Cancer

DTIC Science & Technology

2007-06-01

C-myc amplification in breast cancer: a meta - analysis of its occurrence and prognostic relevance. Br J Cancer, 83: 1688-1695, 2000. 2. Hui, R...Nass SJ, Dickson RB, Trock BJ. C-myc amplification in breast cancer: a meta - analysis of its occurrence and prognostic relevance. Br J Cancer 2000;83...a detailed genomic and expression analysis of the 8p11-p12 amplicon in breast cancer cell lines and identified several novel candidate genes

Purinergic Receptors in Quiescence and Localization of Leukemic Stem Cells

DTIC Science & Technology

2012-05-01

mediating HSPC mobilization. Reportable Outcomes Cho JS, Shen H, Hui Y, Cheng T, Lee SB, Lee BC. 2011. Ewing’s Sarcoma Gene EWS regulates...Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and should not be construed as an...PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER Byeong-Chel Lee, Ph.D. 5e. TASK NUMBER E-Mail: leeb4@upmc.edu 5f. WORK UNIT

L'optique pour la sécurité sanitaire des aliments

NASA Astrophysics Data System (ADS)

Piat, Félix

2017-12-01

Il semble aujourd'hui évident que chaque produit alimentaire commercialisé ne représente aucun danger pour la santé. Cet acquis repose pourtant sur un système complexe de règles et de contrôles appliqués quotidiennement dans les coulisses de l'industrie agro-alimentaire. Les technologies optiques y jouent un rôle prépondérant, permettant de séparer le bon grain de l'ivraie.

Problems of Minority Races in Communist China

DTIC Science & Technology

1960-07-29

The minority races are more serious about their faiths and beliefs than Hans are. Especially, Lamaism in Tibet and Mohammedanism in Han-hui and...be freed by Communist China. No argument can be stranger than this. For Tibetans, Lamaism is their culture and faith. Feudalism and so forth are...if they say: ,.,,.. » "lie are sorry for you. We will free you. < The doctrine of Lamaism has Buddhistic culture on its high level, and we

A Blind Segmentation Approach to Acoustic Event Detection Based on I Vector

DTIC Science & Technology

2013-08-25

Hui Lee1 1 School of ECE, Georgia Institute of Technology , Atlanta, GA. 30332-0250, USA 2 School of Computing, University of Eastern Finland, Finland...recordings obtained at low signal-to-noise-ratio (SNR) enviroments with highly-mixed events in a single acous- tic segment. Research in AED [1] is...2532–2535. [28] C.-C. Chang and C.-J. Lin, “LIBSVM: A library for support vector machines,” ACM Transactions on Intelligent Systems and Technology

Ultrafast Photovoltaic Response in Ferroelectric Nanolayers

DTIC Science & Technology

2016-04-19

Hesse, and M. Alexe, Phys. Rev. Lett. 98, 257601 (2007). [28] P. Emma, R. Akre , J. Arthur, R. Bionta, C. Bostedt, J. Bozek, A . Brachmann, P...David M. Fritz10, Marco Cammarata10, Diling Zhu10, Henrik T. Lemke10,11, Donald A . Walko4, Eric M. Dufresne4, Yuelin Li4, Jörgen Larsson12, David A ...Reis2,9,13, Klaus Sokolowski-Tinten7, Keith A . Nelson6, Andrew M. Rappe5, Paul H. Fuoss3, G. Brian Stephenson3 and Aaron M. Lindenberg2,8.9

Eavesdropping on the improved three-party quantum secret sharing protocol

NASA Astrophysics Data System (ADS)

Gao, Gan

2011-02-01

Lin et al. [Song Lin, Fei Gao, Qiao-yan Wen, Fu-chen Zhu, Opt. Commun. 281 (2008) 4553] pointed out that the multiparty quantum secret sharing protocol [Zhan-jun Zhang, Gan Gao, Xin Wang, Lian-fang Han, Shou-hua Shi, Opt. Commun. 269 (2007) 418] is not secure and proposed an improved three-party quantum secret sharing protocol. In this paper, we study the security of the improved three-party quantum secret sharing protocol and find that it is still not secure. Finally, a further improved three-party quantum secret sharing protocol is proposed.

Publisher Correction: RING tetramerization is required for nuclear body biogenesis and PML sumoylation.

PubMed

Wang, Pengran; Benhenda, Shirine; Wu, Haiyan; Lallemand-Breitenbach, Valérie; Zhen, Tao; Jollivet, Florence; Peres, Laurent; Li, Yuwen; Chen, Sai-Juan; Chen, Zhu; de Thé, Hugues; Meng, Guoyu

2018-05-04

In the originally published version of this Article, the authors Sai-Juan Chen and Zhu Chen were incorrectly listed as being affiliated with 'University Paris Diderot, Sorbonne Paris Cité, INSERM U944, CNRS UMR7212, Equipe labellisée LNCC, Hôpital St. Louis 1, Paris 75475, France', and the affiliation 'Institute of Health Sciences, Shanghai Institutes for Biological Sciences and Graduate School, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China' was inadvertently omitted. These errors have now been corrected in both the PDF and HTML versions of the Article.

Commission 22: Meters, Meteorites and Interplanetary Dust

NASA Astrophysics Data System (ADS)

Watanabe, Junichi; Jenniskens, Peter; Spurný, Pavel; Borovička, Jiří; Campbell-Brown, Margaret; Consolmagno, Guy; Jopek, Tadeusz; Vaubaillon, Jeremie; Williams, Iwan P.; Zhu, Jin

2010-05-01

The business meeting of commission 22 was held at the room 5 in the SulAmerica Convention Center in Rio de Janeiro(14:00-15:30). Fifteen people attended at this meeting:J.Borovička, E.Bowell, G.Consolmagno, D.Green, P. Jenniskens, A. Pellinen-Wannberg, R. Rudawska, J. Watanabe, J. Zhu, P. H. A. Hasselmann, F. Ostroviski, D. A. Oszkiewicz, W. Thuillot, P. Mahajani, and A. Sule. This meeting was managed by Junichi Watanabe, the current C22 Vice-President. The summary of the meeting is described.

Scheme for implementing 1 → M symmetric economical phase-covariant telecloning based on quantum logic network

NASA Astrophysics Data System (ADS)

Zhou, Yan-Hui; Wang, Lei

2012-04-01

The quantum logic network to implement 1 → M symmetric economical phase-covariant telecloning is presented. The scheme includes two parts: the first part is used to create the telecloning channel and the second part to teleport the input state. The telecloning channel which works without ancilla is constructed by two kinds of elementary unitary transformations, single-qubit rotation and multiple-qubit controlled operation. The probability of success is 50%, which is the same with the scheme in [Meng, F.Y.; Zhu, A.D. J. Mod. Opt. 2009, 56, 1255-1259].

Doping Asymmetry Problem in ZnO: Current Status and Outlook. A Review of Experimental and Theoretical Efforts Focused on Achieving P-Type ZnO Suitable for Light-Emitting Optoelectronic Devices for the Blue/Ultraviolet Spectral Range

DTIC Science & Technology

2009-04-24

it seems at a first glance, because the isovalent co- doping of ZnO will result also in an increase of the band gap which usually gives rise to an...J.G. Lu, H.P. He, L.X. Chen, X.Q. Gu, J.Y. Huang, L.P. Zhu, and B.H. Zhao, “Na doping concentration tuned conductivity of ZnO films via pulsed laser...recently as a promising material for a variety of applications. To a large extent, the renewed interest in ZnO is fuelled by its wide direct band gap (3.3

Supercapacitors: A Hierarchical Carbon Derived from Sponge-Templated Activation of Graphene Oxide for High-Performance Supercapacitor Electrodes (Adv. Mater. 26/2016).

PubMed

Xu, Jin; Tan, Ziqi; Zeng, Wencong; Chen, Guanxiong; Wu, Shuilin; Zhao, Yuan; Ni, Kun; Tao, Zhuchen; Ikram, Mujtaba; Ji, Hengxing; Zhu, Yanwu

2016-07-01

H. Ji, Y. Zhu, and co-workers demonstrate a 3D hierarchically porous carbon by introducing a polyurethane sponge to template graphene oxide into a 3D interconnected structure while KOH activation generates abundant micropores in its backbone. As described on page 5222, a supercapacitor assembled with this carbon material achieves a high energy density of 89 W h kg(-1) (64 W h L(-1) ) and outstanding power density due to its shortened ion transport distance in three dimensions. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Investigating the impact of pain, age, Gross Motor Function Classification System, and sex on health-related quality of life in children with cerebral palsy.

PubMed

Findlay, Briar; Switzer, Lauren; Narayanan, Unni; Chen, Shiyi; Fehlings, Darcy

2016-03-01

To explore whether health-related quality of life (HRQOL) can be predicted by pain, age, Gross Motor Function Classification System (GMFCS) level, and sex in children with cerebral palsy (CP) and whether different pain etiologies have varying effects on HRQOL. Children with CP aged 3 to 19 years and their caregivers were consecutively recruited. Caregivers reported their child's pain (Health Utilities Index 3 [HUI3] pain subset) and HRQOL (DISABKIDS questionnaires). Physicians identified pain etiologies. A multiple linear regression model determined whether pain, GMFCS level, sex, and age predicted HRQOL. An ANOVA evaluated the effects of pain etiologies on HRQOL. Three hundred and forty-four participants were approached and 87% (n=300) participated. Sufficient data were available on 248 (72% of total sample). Sixty-six participants (27%) formed the pain group with HUI3 pain scores of at least 3. The presence of pain and increasing age significantly negatively predicted HRQOL (p<0.001, R(2) =0.141), while GMFCS and sex did not. Musculoskeletal deformity (24%) and hypertonia (18%) were the most frequent pain causes. HRQOL statistically differed depending on the pain etiology (p=0.028) with musculoskeletal deformity showing the lowest mean HRQOL. The presence of pain and increasing age negatively predict HRQOL in CP. musculoskeletal deformity has the greatest negative impact on HRQOL. © 2015 Mac Keith Press.

Cost-effectiveness analysis of cochlear dose reduction by proton beam therapy for medulloblastoma in childhood.

PubMed

Hirano, Emi; Fuji, Hiroshi; Onoe, Tsuyoshi; Kumar, Vinay; Shirato, Hiroki; Kawabuchi, Koichi

2014-03-01

The aim of this study is to evaluate the cost-effectiveness of proton beam therapy with cochlear dose reduction compared with conventional X-ray radiotherapy for medulloblastoma in childhood. We developed a Markov model to describe health states of 6-year-old children with medulloblastoma after treatment with proton or X-ray radiotherapy. The risks of hearing loss were calculated on cochlear dose for each treatment. Three types of health-related quality of life (HRQOL) of EQ-5D, HUI3 and SF-6D were used for estimation of quality-adjusted life years (QALYs). The incremental cost-effectiveness ratio (ICER) for proton beam therapy compared with X-ray radiotherapy was calculated for each HRQOL. Sensitivity analyses were performed to model uncertainty in these parameters. The ICER for EQ-5D, HUI3 and SF-6D were $21 716/QALY, $11 773/QALY, and $20 150/QALY, respectively. One-way sensitivity analyses found that the results were sensitive to discount rate, the risk of hearing loss after proton therapy, and costs of proton irradiation. Cost-effectiveness acceptability curve analysis revealed a 99% probability of proton therapy being cost effective at a societal willingness-to-pay value. Proton beam therapy with cochlear dose reduction improves health outcomes at a cost that is within the acceptable cost-effectiveness range from the payer's standpoint.

Broadband enhanced transmission of acoustic waves through serrated metal gratings

NASA Astrophysics Data System (ADS)

Qi, Dong-Xiang; Fan, Ren-Hao; Deng, Yu-Qiang; Peng, Ru-Wen; Wang, Mu; Jiangnan University Collaboration

In this talk, we present our studies on broadband properties of acoustic waves through metal gratings. We have demonstrated that serrated metal gratings, which introduce gradient coatings, can give rise to broadband transmission enhancement of acoustic waves. Here, we have experimentally and theoretically studied the acoustic transmission properties of metal gratings with or without serrated boundaries. The average transmission is obviously enhanced for serrated metal gratings within a wide frequency range, while the Fabry-Perot resonance is significantly suppressed. An effective medium hypothesis with varying acoustic impedance is proposed to analyze the mechanism, which was verified through comparison with finite-element simulation. The serrated boundary supplies gradient mass distribution and gradient normal acoustic impedance, which could efficiently reduce the boundary reflection. Further, by increasing the region of the serrated boundary, we present a broadband high-transmission grating for wide range of incident angle. Our results may have potential applications to broadband acoustic imaging, acoustic sensing and new acoustic devices. References: [1] Dong-Xiang Qi, Yu-Qiang Deng, Di-Hu Xu, Ren-Hao Fan, Ru-Wen Peng, Ze-Guo Chen, Ming-Hui Lu, X. R. Huang and Mu Wang, Appl. Phys. Lett. 106, 011906 (2015); [2] Dong-Xiang Qi, Ren-Hao Fan, Ru-Wen Peng, Xian-Rong Huang, Ming-Hui Lu, Xu Ni, Qing Hu, and Mu Wang, Applied Physics Letters 101, 061912 (2012).

The effect of physician supply on health status: Canadian evidence.

PubMed

Piérard, Emmanuelle

2014-10-01

We estimate the relationship between per capita supply of physicians, both general practitioners and specialists, and health status of Canadians. We use data from the Canadian National Population Health Survey and the Canadian Institute for Health Information. Two measures of quality of life, self-assessed health status and the Health Utility Index, are explored. Random effects ordered probits are used to model self-assessed health status, and quantile regressions are used for the Health Utility Index. A higher supply of general practitioners is correlated with better health outcomes as measured by both measures of health status, albeit for different age groups, and it is correlated with a higher HUI for some individuals who report having a chronic condition. A higher supply of specialists is correlated with worse health outcomes for the HUI for some individuals. It is possible that a higher supply of general practitioners increases the likelihood of diagnosing and treating health conditions in a timely manner and that this in turn affects health status. Specialists, due to the nature of their expertise could affect negatively health, both through the use of riskier procedures and due to their clientele being in relatively worse health. Based on our findings, we therefore would recommend maintaining a robust supply and distribution of GPs across Canada. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

[Efficiency of 27-plex single nucleotide polymorphism multiplex system for ancestry inference in different populations].

PubMed

Feng, Xing-Ling; Sun, Qi-Fan; Liu, Hong; Wei, Yi-Liang; DU, Wei-An; Li, Cai-Xia; Chen, Ling; Liu, Chao

2016-04-20

To validate the efficiency of 27-plex single nucleotide polymorphism (SNP) multiplex system for ancestry inference. The 27-plex SNP system was validated for its sensitivity and species specificity. A total of 533 samples were collected from African, Southern Chinese Han, China's ethic minorities (Yi, Hui, Miao, Tibet, and Uygur), European, Central Asian, Western Asian, Southern Asian, Southeast Asian and South American populations for clustering analysis of the genotypes by citing 3 representative continental ancestral groups [East Asia (CHB), Europe (CEU), and Africa (YRI)] from HapMap database. The system sensitivity is 0.125 ng. Twenty and six genotypes were detected in chimpanzee and monkeys, respectively. Except in rs10496971, no more products were found in other animals. The system was capable of differentiating intercontinental populations but not of distinguishing between East Asian and Southeast Asian population or between Southern Chinese Han population and Chinese Ethnic populations (Hui, Miao, Yi and Tibet). This system achieved a 100% accuracy for intercontinental population source inference for 46 blind test samples. 27-plex SNPs multiplex system has a high sensitivity and species specificity and can correctly differentiate the ancestry origins of individuals from African, European and East Asian for criminal case investigation. But this system is not capable of distinguishing subpopulation groups and more specific ancestry-informative markers are needed to improve its recognition of Southeast Asian and Chinese ethnic populations.

Measuring health-related quality of life in population-based studies of coronary heart disease: comparing six generic indexes and a disease-specific proxy score.

PubMed

Garster, Noelle C; Palta, Mari; Sweitzer, Nancy K; Kaplan, Robert M; Fryback, Dennis G

2009-11-01

To compare HRQoL differences with CHD in generic indexes and a proxy CVD-specific score in a nationally representative sample of U.S. adults. The National Health Measurement Study, a cross-sectional random-digit-dialed telephone survey of adults aged 35-89, administered the EQ-5D, QWB-SA, HUI2, HUI3, SF-36v2 (yielding PCS, MCS, and SF-6D), and HALex. Analyses compared 3,350 without CHD (group 1), 265 with CHD not taking chest pain medication (group 2), and 218 with CHD currently taking chest pain medication (group 3), with and without adjustment for demographic variables and comorbidities. Data on 154 patients from heart failure clinics were used to construct a proxy score utilizing generic items probing CVD symptoms. Mean scores differed between CHD groups for all indexes with and without adjustment (P < 0.0001 for all except MCS P = 0.018). Unadjusted group 3 versus 1 differences were about three times larger than for group 2 versus 1. Standardized differences for the proxy score were similar to those for generic indexes, and were about 1.0 for all except MCS for group 3 versus 1. Generic indexes capture differences in HRQoL in population-based studies of CHD similarly to a score constructed from questions probing CVD-specific symptoms.

Re-ranking via User Feedback: Georgetown University at TREC 2015 DD Track

DTIC Science & Technology

2015-11-20

Re-ranking via User Feedback: Georgetown University at TREC 2015 DD Track Jiyun Luo and Hui Yang Department of Computer Science, Georgetown...involved in a search process, the user and the search engine. In TREC DD , the user is modeled by a simulator, called “jig”. The jig and the search engine...simulating user is provided by TREC 2015 DD Track organizer, and is called “jig”. There are 118 search topics in total. For each search topic, a short

JPRS Report China

DTIC Science & Technology

1988-11-07

in charge of technology, and their success in this election put them in a favorable position in future cabinet reshuffles. Kuo Wan- jung [6753 1238...very high, Kuo Wan- jung , as the first female executive official, still has the opportunity to scale new heights. Party Organs Party organs won a... Kuo Shu-min 6753 3219 2404, Hsu Li-chuan 6079 7787 1227, Li Chi-kuang 2621 1323 0342, and Chang Hui-chen 1728 1979 3791: "The Structure of the New

Functions and regulation of the multitasking FANCM family of DNA motor proteins.

PubMed

Xue, Xiaoyu; Sung, Patrick; Zhao, Xiaolan

2015-09-01

Members of the conserved FANCM family of DNA motor proteins play key roles in genome maintenance processes. FANCM supports genome duplication and repair under different circumstances and also functions in the ATR-mediated DNA damage checkpoint. Some of these roles are shared among lower eukaryotic family members. Human FANCM has been linked to Fanconi anemia, a syndrome characterized by cancer predisposition, developmental disorder, and bone marrow failure. Recent studies on human FANCM and its orthologs from other organisms have provided insights into their biological functions, regulation, and collaboration with other genome maintenance factors. This review summarizes the progress made, with the goal of providing an integrated view of the functions and regulation of these enzymes in humans and model organisms and how they advance our understanding of genome maintenance processes. © 2015 Xue et al.; Published by Cold Spring Harbor Laboratory Press.

CRISPR/Cas9 mediates efficient conditional mutagenesis in Drosophila.

PubMed

Xue, Zhaoyu; Wu, Menghua; Wen, Kejia; Ren, Menda; Long, Li; Zhang, Xuedi; Gao, Guanjun

2014-09-05

Existing transgenic RNA interference (RNAi) methods greatly facilitate functional genome studies via controlled silencing of targeted mRNA in Drosophila. Although the RNAi approach is extremely powerful, concerns still linger about its low efficiency. Here, we developed a CRISPR/Cas9-mediated conditional mutagenesis system by combining tissue-specific expression of Cas9 driven by the Gal4/upstream activating site system with various ubiquitously expressed guide RNA transgenes to effectively inactivate gene expression in a temporally and spatially controlled manner. Furthermore, by including multiple guide RNAs in a transgenic vector to target a single gene, we achieved a high degree of gene mutagenesis in specific tissues. The CRISPR/Cas9-mediated conditional mutagenesis system provides a simple and effective tool for gene function analysis, and complements the existing RNAi approach. Copyright © 2014 Xue et al.

[Version and compilation of Harikyuuhousouyou of Vietnamese medical book].

PubMed

Du, Fengjuan; Xiao, Yongzhi

2018-02-12

Harikyuuhousouyou （《》）was written in 1827 and the author is unknown. The book has only one version which is collected by the National Library of Vietnam. The book contains one volume and includes contraindication of acupuncture and moxibustion, meridian points, point locations, indications and the therapeutic methods at extraordinary points. They are mainly cited from Zhen Jiu Da Quan (《》 Great Compendium on Acupuncture and Moxibustion ) by XU Feng , Yi Xue Ru Men (《》 Elementary Medicine ) by LI Chan and Shou Shi Bao Yuan (《》 Longevity and Health Preservation ) by GONG Tingxian in the Ming Dynasty. In the paper, in view of the characteristics of version and compilation, the hand-coped book was introduced. It was explored that Vietnam acupuncture absorbed Chinese medicine and emphasized clinical practice rather than theoretic statement.

Photochemically stable fluorescent heteroditopic ligands for zinc ion.

PubMed

Zhang, Lu; Zhu, Lei

2008-11-07

Photochemically stable fluorescent heteroditopic ligands (9 and 10) for zinc ion were prepared and studied. Two independent metal coordination-driven photophysical processes, chelation-enhanced fluorescence (CHEF) and internal (or intramolecular) charge transfer (ICT), were designed into our heteroditopic ligand framework. This strategy successfully relates three coordination states of a ligand, non-, mono-, and dicoordinated, to three fluorescence states, fluorescence OFF, ON at one wavelength, and ON at another wavelength. This ligand platform has provided chemical foundation for applications such as the quantification of zinc concentration over broad ranges (Zhang, L.; Clark, R. J.; Zhu, L. Chem.-Eur. J. 2008, 14, 2894-2903) and molecular logic functions (Zhang, L.; Whitfield, W. A.; Zhu, L. Chem. Commun. 2008, 1880-1882). The binding stoichiometries of dipicolylamino and 2,2'-bipyridyl, the two binding sites featured in heteroditopic ligands 7-10, were studied in acetonitrile using both Job's method of continuous variation and isothermal titration calorimetry (ITC). The fluorescence enhancement of 7-10 upon the formation of monozinc complexes (defined as the fluorescence quantum yield ratio of monozinc complex and free ligand) is qualitatively related to the highest occupied molecular orbital (HOMO) energy levels of their fluorophores. This is consistent with our hypothesis on the thermodynamics of the coordination-driven photophysical processes embodied in the designed heteroditopic system, which was supported by cyclic voltammetry studies. In conclusion, compounds 9 and 10 not only possess better photochemical stability but also display a higher degree of fluorescence turn-on upon formation of monozinc complexes than their vinyl counterparts 7 and 8.

Effect of Service Environment on Composite Materials

DTIC Science & Technology

1980-08-01

AGARC -CP-288 . z AGARD Conference Procee•dings No.288 Effect of Service Environment on Composite Materials M1TflIBInj4 STATE 9s~k 7- II LLU...ORGANISATION DU TRAITE DE L’ATLANTI )UE NOR3) AGARD Conference Proceedings 1, o.288 EFFECT OF SERVICE ENVIRONM ENT ONj I COMPOSITE MATERIALS --- I... composites soumis aux divers types d’agressions que l’on recouvre aujourd’hui du vocable d’...environnement". On doit admettre que cette revue 6tait part

Discriminant Function Job Analysis in Three Army Technical MOS

DTIC Science & Technology

1980-07-01

8217: ATAA-SL (TFCH 118PARY) I UNI1-0Ni- tD SFRVhLS U1411 Or THL kt.ALIfi SC! DEPANIMENI’ OF PSYCHIATRf I HUI AN LLSU R( ES kS( H UOr< (1-rMkPD) i H-U IRR...USA TRAINING SUPPDRT CEI’J1H UEVLL SYb T E’t4S 1Mb + DEVICFS DiNE-CIORATF. I AF-IRL !ECHWIOLOI.Y DFC (H) I PUI)UE UNIV DEN’I OF PS>YLDiULODILAL

Characterizing and Targeting Replication Stress Response Defects in Breast Cancer

DTIC Science & Technology

2014-08-01

NUMBER Shiaw-Yih Lin , Chun-Jen Lin, Lili Gong, Hui Dai, Ju-Seog Lee 5e. TASK NUMBER E-Mail: sylin@mdanderson.org The University of...the mammary fat pads of female nude mice. We closely monitored tumor formation in the mice. Notably, tumors began to form in 3 of 10 mice injected...and two independent TUSC4-knockdown MCF-10A cell lines (TUSC4 #1 and TUSC4 #4) were injected per mouse into mammary fat pads of 6-week-old female nude

Les traces matérielles de la Carte du Ciel. Le cas des observatoires d'Alger et de Bordeaux.

NASA Astrophysics Data System (ADS)

Le Guet Tully, F.; Davoigneau, J.; Lamy, J.; de La Noë, J.; Rousseau, J.-M.; Sadsaoud, H.

2008-06-01

Le chapitre évoque les traces matérielles de la Carte du ciel subsistant dans les observatoires d'Alger et de Bordeaux. Les auteurs examinent d'abord l'opération d'inventaire du patrimoine astronomique entreprise à partir du milieu des années 1990. Ils examinent ensuite les éléments concrets constituant aujourd'hui le patrimoine de la Carte du Ciel : lunettes, abris, accessoires, laboratoires, réseaux, plaques de verre, registres, machines à mesurer les clichés, et cartes.

Self-Remediating Energetic Fills Based on Cyclic Dinitroureas

DTIC Science & Technology

2016-12-01

159 ° C (sample- dependent) c ,e Detonation pressure PCJ (GPa) 38.7h 46.2i - 37.98 g Detonation velocity D (km/sec) 9.07 j ~9.75 k,l 8.67 b 8.81 g...Gao, S.-L.; Zhu, C .-H.; Ning, B.-K.; Chen, P.; Luo, Y.; Song, J .- R.; Shi, Q.-Z. Chin. J . Chem. 2004, 22, 1075. TNGU was chosen to move forward...R.E.; DeSesso, J . II; Vogel, C . M. Comparison of the Relative Risks of CL-20 and RDX. Noblis Technical Report, July 2007; http://www.serdp- estcp.org

Identification of evodiamine as the bioactive compound in evodia (Evodia rutaecarpa Benth.) fruit extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ).

PubMed

Rebhun, John F; Roloff, Samantha J; Velliquette, Rodney A; Missler, Stephen R

2015-03-01

The dried unripe fruit from Evodia rutaecarpa Benth., known as Wu zhu yu in China, has long been used in traditional Chinese medicine. In this research, we provide evidence that evodia fruit extract activates peroxisome proliferator-activated receptor gamma (PPARγ) and, as identified through HPLC fractionation and mass spectroscopy, the activating phytochemical is evodiamine. Evodiamine was shown to bind to and activate PPARγ. It was also shown to activate PPARγ-regulated gene expression in human hepatoma cells similar to known PPARγ ligands and that the expression was blocked by a PPARγ specific antagonist. Copyright © 2015. Published by Elsevier B.V.

[Brief investigation on the issue of Zhen Dan(Cinnabar, HgS) irrelevant to Qian Dan (Minium, Pb(3)O(4))].

PubMed

Shen, S N

2017-07-28

Zhen Dan, the abbreviated form of Zhen Dan Sha, or called Zhu Sha (Cinnabar, HgS). It can be ruled out that Zhen Dan is the nickname of Qian Dan (Minium, Pb(3)O(4)) through the homologous formulas contrast. The prescriptions containing Zhen Dan in the Zheng lei ben cao ( Classified Materia Medica ) was put under the "attached prescriptions" of Qian Dan, while Zhong yao da ci dian ( Great Dictionary of Chinese Materia Medica )and Zhong hua ben cao ( Chinese Herbology )all definitelyconfirmed that Zhen Dan is the other name of Qian Dan, which are wrong and should be corrected.

Predicting Adherence and Persistence with Oral Bisphosphonate Therapy in an Integrated Health Care Delivery System.

PubMed

Hui, Rita L; Adams, Annette L; Niu, Fang; Ettinger, Bruce; Yi, David K; Chandra, Malini; Lo, Joan C

2017-04-01

excess of the 60-day allowable gap between prescription/refills (median cumulative nonpersistence = 0.65, IQR = 0.30-1.25 years). Women with mPDC ≥ 75% during the first year had a 12-fold and 6-fold increased odds of mPDC ≥ 75% during year 2 and year 3, respectively. BP discontinuation rates are highest for women during the first year. Among those continuing treatment in subsequent years, adherence rates were relatively stable. Persistence and adherence varied slightly by age and was somewhat higher in Asians, contributing to differences in cumulative BP exposure. We also found evidence that optimal adherence in the first year was highly predictive of optimal adherence in the subsequent 1-2 years. Hence, subgroups of patients receiving oral BP drugs may require different levels of support and monitoring to maximize treatment benefit, especially based on early patterns of use. This study was supported by grants from the Kaiser Permanente Northern California Community Benefit Program and the National Institutes of Health, 1R01AG047230-01A1. The opinions expressed in this publication are solely the responsibility of the authors and do not represent the official views of Kaiser Permanente or the National Institutes of Health. Hui, Yi, and Chandra have received past research funding from Amgen not related to the current study. Adams has received research funding from Amgen, Merck, and Otsuka not related to the current study. Niu has received research funding from Bristol-Myers Squibb not related to the current study. Ettinger has received past legal fees in litigation involving Fosamax. Lo has received past research funding from Amgen and current research funding from Sanofi not related to the current study. The data from this study were presented at the Academy of Managed Care Pharmacy Annual Meeting; April 19-22, 2016; San Francisco, California. Study concept and design were contributed primarily by Hui and Lo, along with Adams, Niu, Yi, and Ettinger. Hui took the lead

The Middle East Respiratory Syndrome Coronavirus - A Continuing Risk to Global Health Security.

PubMed

Azhar, Esam I; Lanini, Simone; Ippolito, Giuseppe; Zumla, Alimuddin

2017-01-01

Two new zoonotic coronaviruses causing disease in humans (Zumla et al. 2015a; Hui and Zumla 2015; Peiris et al. 2003; Yu et al. 2014) have been the focus of international attention for the past 14 years due to their epidemic potential; (1) The Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) (Peiris et al. 2003) first discovered in China in 2001 caused a major global epidemic of the Severe Acute Respiratory Syndrome (SARS). (2) The Middle East respiratory syndrome coronavirus (MERS-CoV) is a new corona virus isolated for the first time in a patients who died of severe lower respiratory tract infection in Jeddah (Saudi Arabia) in June 2012 (Zaki et al. 2012). The disease has been named Middle East Respiratory Syndrome (MERS) and it has remained on the radar of global public health authorities because of recurrent nosocomial and community outbreaks, and its association with severe disease and high mortality rates (Assiri et al. 2013a; Al-Abdallat et al. 2014; Memish et al. 2013a; Oboho et al. 2015; The WHO MERS-CoV Research Group 2013; Cotten et al. 2013a; Assiri et al. 2013b; Memish et al. 2013b; Azhar et al. 2014; Kim et al. 2015; Wang et al. 2015; Hui et al. 2015a). Cases of MERS have been reported from all continents and have been linked with travel to the Middle East (Hui et al. 2015a; WHO 2015c). The World Health Organization (WHO) have held nine meetings of the Emergency Committee (EC) convened by the Director-General under the International Health Regulations (IHR 2005) regarding MERS-CoV (WHO 2015c). There is wishful anticipation in the political and scientific communities that MERS-CoV like SARS-CoV will disappear with time. However it's been nearly 4 years since the first discovery of MERS-CoV, and MERS cases continue to be reported throughout the year from the Middle East (WHO 2015c). There is a large MERS-CoV camel reservoir, and there is no specific treatment or vaccine (Zumla et al. 2015a). With 10 million people visiting Saudi Arabia every

Habitat use in eight populations of Sceloporus grammicus (Squamata: Phrynosomatidae) from the Mexican Plateau.

PubMed

Leyte-Manrique, Adrian; Hernández-Salinas, Uriel; Ramírez-Bautista, Aurelio; Mata-Silva, Vicente; Marshall, Jonathon C

2017-05-01

Studies on habitat use have often helped explain observed variation in morphology, behavior and reproductive characteristics among populations within a single species. Here we analyze morphological and ecological characteristics of individuals from the Sceloporus grammicus species complex from 7 different localities (CER, El Cerezo; PAC, Pachuca; HUI, Huichapan; EZA, Emiliano Zapata; SMR, San Miguel Regla; LMJ, La Mojonera; and LMZ, La Manzana) in the state of Hidalgo, and one locality (Cahuacán) in the State of Mexico. A canonical correspondence analysis (CCA) showed that females from PAC, EZA, LMZ, HUI, SMR and CAH populations use similar microhabitats characterized mostly by bare soil, in females from LMJ and CER use microhabitats characterized primarily by vegetation and rocks. Females were observed using 12 different types of perches. With regard to perch height use, the CCA showed that females from PAC, LMJ, LMZ, SMR, CER and CAH populations were correlated with height to nearest perch (HNP), in the rest of the females were not related to any perch use variable. In contrast, the CCA showed that males from PAC, LMJ and CAH were characterized by microhabitats with higher vegetal coverage, while males from LMZ and CER used microhabitats composed of bare soil, but males from HUI and SMR populations used microhabitats composed chiefly of bare soil and rocks. With respect to perch height use, the CCA showed that males from PAC, LMJ, EZA and LMZ were correlated with distance to the nearest perch, but the rest of the males were not correlated with any perch use variables. Males were observed in 9 different perch types. The males were larger than the females in all morphological variables analyzed. Moreover, in both sexes the snout-vent length is positively correlated with all morphological variables, and although both the slope and ordinate of the origin of all morphological variables were larger in males than females, the analysis of covariance indicated that there

The ability of cancer-specific and generic preference-based instruments to discriminate across clinical and self-reported measures of cancer severities

PubMed Central

2011-01-01

Objective To evaluate the validity of cancer-specific and generic preference-based instruments to discriminate across different measures of cancer severities. Methods Patients with breast (n = 66), colorectal (n = 57), and lung (n = 61) cancer completed the EORTC QLQ-C30 and the FACT-G, as well as three generic instruments: the EQ-5D, the SF-6D, and the HUI2/3. Disease severity was quantified using cancer stage, Eastern Cooperative Oncology Group Performance Status (ECOG-PS) score, and self-reported health status. Comparative analyses confirmed the multi-dimensional conceptualization of the instruments in terms of construct and convergent validity. Results In general, the instruments were able to discriminate across severity measures. The instruments demonstrated moderate to strong correlation with each other (r = 0.37-0.73). Not all of the measures could discriminate between different groups of disease severity: the EQ-5D and SF-6D were less discriminative than the HUI2/3 and the cancer-specific instruments. Conclusion The cancer-specific and generic preference-based instruments demonstrated to be valid in discriminating across levels of ECOG-PS scores and self-reported health states. However, the usefulness of the generic instruments may be limited if they are not able to detect small changes in health status within cancer patients. This raises concerns regarding the appropriateness of these instruments when comparing different cancer treatments within an economic evaluation framework. PMID:22123196

Health-Related Quality of Life in Adolescents With or at Risk for Type 2 Diabetes Mellitus

PubMed Central

Rhodes, Erinn T.; Goran, Michael I.; Lieu, Tracy A.; Lustig, Robert H.; Prosser, Lisa A.; Songer, Thomas J.; Weigensberg, Marc J.; Weinstock, Ruth S.; Gonzalez, Tessa; Rawluk, Kaitlin; Zoghbi, Roula M.; Ludwig, David S.; Laffel, Lori M.

2015-01-01

Objective We evaluated how adolescents with or at risk for type 2 diabetes (T2DM) and their parent/guardians (parents) perceive adolescents’ health-related quality of life (HRQOL). Study Design We interviewed overweight/obese, 12–18-year-old youth with T2DM, prediabetes, or insulin resistance (IR) and one parent from 5 US sites. Assessments included Pediatric Quality of Life Inventory™ (PedsQL), Health Utilities Index (HUI3), family conflict and diabetes burden. Results Among 108 adolescents, diagnoses included 40.7% T2DM, 25.0% prediabetes, and 34.3% IR. PedsQL summary score (SS) was higher among adolescents vs. parents (p=0.02). Parents rated physical functioning lower than adolescents (p<0.0001), but there were no differences in psychosocial health. Adolescent PedsQL SS did not differ by diagnosis but was inversely associated with adolescent BMI z-score (p=0.0004) and family conflict (p<0.0001) and associated with race/ethnicity (p<0.0001). Number of adolescent comorbidities (p=0.007) and burden of diabetes care (p<0.05) were inversely associated with parent PedsQL SS (p<0.05). There were no differences in HUI3. Conclusions Parents perceive their adolescents’ physical functioning as more impaired than adolescents themselves. Contextual factors including severity of obesity, race/ethnicity, family conflict and burden of diabetes care influence HRQOL. Family-based approaches to treatment and prevention of T2DM may benefit from increased attention to the biopsychosocial context. PMID:22217471

The Poetics of a School Shooter: Decoding Political Signification in Cho Seung-Hui's Multimedia Manifesto

ERIC Educational Resources Information Center

Carvalho, Edward J.

2010-01-01

In 2007, against a tragically ironic backdrop of National Poetry Month, April indeed was "the cruellest month" (Eliot 1922, I.1). The media spotlight during that time repositioned from Iraq and Afghanistan to Blacksburg, Virginia, where a stateside guerilla incursion at Virginia Tech would mark the single worst episode of school shooting…

The on-orbit calibration of geometric parameters of the Tian-Hui 1 (TH-1) satellite

NASA Astrophysics Data System (ADS)

Wang, Jianrong; Wang, Renxiang; Hu, Xin; Su, Zhongbo

2017-02-01

The on-orbit calibration of geometric parameters is a key step in improving the location accuracy of satellite images without using Ground Control Points (GCPs). Most methods of on-orbit calibration are based on the self-calibration using additional parameters. When using additional parameters, different number of additional parameters may lead to different results. The triangulation bundle adjustment is another way to calibrate the geometric parameters of camera, which can describe the changes in each geometric parameter. When triangulation bundle adjustment method is applied to calibrate geometric parameters, a prerequisite is that the strip model can avoid systematic deformation caused by the rate of attitude changes. Concerning the stereo camera, the influence of the intersection angle should be considered during calibration. The Equivalent Frame Photo (EFP) bundle adjustment based on the Line-Matrix CCD (LMCCD) image can solve the systematic distortion of the strip model, and obtain high accuracy location without using GCPs. In this paper, the triangulation bundle adjustment is used to calibrate the geometric parameters of TH-1 satellite cameras based on LMCCD image. During the bundle adjustment, the three-line array cameras are reconstructed by adopting the principle of inverse triangulation. Finally, the geometric accuracy is validated before and after on-orbit calibration using 5 testing fields. After on-orbit calibration, the 3D geometric accuracy is improved to 11.8 m from 170 m. The results show that the location accuracy of TH-1 without using GCPs is significantly improved using the on-orbit calibration of the geometric parameters.

Official Guard and Reserve Manpower Strengths and Statistics, Fiscal Year 2010 Summary

DTIC Science & Technology

2010-01-01

OU)r-r-ooinin \\DCD^(^COininWU)\\flhhCDCOaiOaɛim^ COrn <’lOhU)U1H(N|>li)’JO<J30llOiNU)OCNn<N ooocftrHinMMcno»H^MrHU)or^w^pi^or^OrHui(»\\Dr>i^r^rnoor...Olilr1NClcoal0^ort^^flln^ ooo(^l^Kl^ coB )^^^^cD^^co^colnnfO(n^^oalcoln^a)1’^mrl^^oHoolnflDlfl^ oinooocDaDr-vocrtr4coa3oocN(Nr-<Nmomf^oor^ina^fninooo-<j

Regularization of the big bang singularity with random perturbations

NASA Astrophysics Data System (ADS)

Belbruno, Edward; Xue, BingKan

2018-03-01

We show how to regularize the big bang singularity in the presence of random perturbations modeled by Brownian motion using stochastic methods. We prove that the physical variables in a contracting universe dominated by a scalar field can be continuously and uniquely extended through the big bang as a function of time to an expanding universe only for a discrete set of values of the equation of state satisfying special co-prime number conditions. This result significantly generalizes a previous result (Xue and Belbruno 2014 Class. Quantum Grav. 31 165002) that did not model random perturbations. This result implies that the extension from a contracting to an expanding universe for the discrete set of co-prime equation of state is robust, which is a surprising result. Implications for a purely expanding universe are discussed, such as a non-smooth, randomly varying scale factor near the big bang.

Energy transfer ultraviolet photodetector with 8-hydroxyquinoline derivative-metal complexes as acceptors

NASA Astrophysics Data System (ADS)

Wu, Shuang-Hong; Li, Wen-Lian; Chen, Zhi; Li, Shi-Bin; Wang, Xiao-Hui; Wei, Xiong-Bang

2015-02-01

We choose 8-hydroxyquinoline derivative-metal complexes (Beq, Mgq, and Znq) as the acceptors (A) and 4,4',4”-tri-(2-methylphenyl phenylamino) triphenylaine (m-MTDATA) as the donor (D) respectively to study the existing energy transfer process in the organic ultraviolet (UV) photodetector (PD), which has an important influence on the sensitivity of PDs. The energy transfer process from D to A without exciplex formation is discussed, differing from the working mechanism of previous PDs with Gaq [Zisheng Su, Wenlian Li, Bei Chu, Tianle Li, Jianzhuo Zhu, Guang Zhang, Fei Yan, Xiao Li, Yiren Chen and Chun-Sing Lee 2008 Appl. Phys. Lett. 93 103309)] and REq [J. B. Wang, W. L. Li, B. Chu, L. L. Chen, G. Zhang, Z. S. Su, Y. R. Chen, D. F. Yang, J. Z. Zhu, S. H. Wu, F. Yan, H. H. Liu, C. S. Lee 2010 Org. Electron. 11 1301] used as an A material. Under 365-nm UV irradiation with an intensity of 1.2 mW/cm2, the m-MTDATA:Beq blend device with a weight ratio of 1:1 shows a response of 192 mA/W with a detectivity of 6.5× 1011 Jones, which exceeds those of PDs based on Mgq (146 mA/W) and Znq (182 mA/W) due to better energy level alignment between m-MTDATA/Beq and lower radiative decay. More photophysics processes of the PDs involved are discussed in detail. Project supported by the National Natural Science Foundation of China (Grant Nos. 61371046, 61405026, 61474016, and 61421002) and China Postdoctoral Science Foundation (Grant No. 2014M552330).

Herbal compatibility of traditional Chinese medical formulas for acquired immunodeficiency syndrome.

PubMed

Cui, Meng; Li, Jinghua; Li, Haiyan; Song, Chunxin

2012-09-01

Because herbal compatibility is one of the most important reasons why Traditional Chinese Medcine (TCM) formulas are effective for acquired immunodeficiency syndrome (AIDS), our study aimed to determine the compatibility of herbs based on published AIDS clinical research in Chinese periodicals. To achieve this aim, we designed a new data-mining algorithm according to TCM data characteristics. We found 25 clinical AIDS studies, all using Chinese herbs for treatment, in the Traditional Chinese Medicine Database System, and information on diagnosis and treatment was extracted. To find out herbal compatibility, especially the formulae for herbal combinations, we proposed an improved association rule algorithm based on the frequency of combinations. In this algorithm, all the compatibility relationships were displayed in a tree structure, by which the relationship between formulas and their derivation could be clearly inferred. Data analysis showed that approximately 100 herbs have been used for treating AIDS. Based on the whole herb compatibility tree, we calculated a basic formula for AIDS: Huang Qi combined with Ren Shen, Fu Ling, Bai Zhu, Bai Zhu, Dang Gui, and Bai Shao. This formula, deriving from most of clinical prescriptions, and was chosed by most of clinicians for AIDS treatment. From data mining we found that Qi replenishment and detoxification were the main treatment principles, which coincided with the AIDS pathological mechanism in which immune function is destroyed by human immunodeficiency virus (HIV). Our data-mining results suggest that the core TCM treatment of AIDS is replenishing Qi and detoxification, by which AIDS patients' immune system may be enhanced. Compatibility of Huang Qi with some frequently-used herbs have shown real efficacy in clinical practice, which warrants pharmacological research in the future.

Deep seismic structure of the northeastern South China Sea: Origin of a high-velocity layer in the lower crust

NASA Astrophysics Data System (ADS)

Wan, Kuiyuan; Xia, Shaohong; Cao, Jinghe; Sun, Jinlong; Xu, Huilong

2017-04-01

We present a 2-D seismic tomographic image of the crustal structure along the OBS2012 profile, which delineates the Moho morphology and magmatic features of the northeastern South China Sea margin. The image was created by forward modeling (RayInvr) and traveltime tomographic inversion (Tomo2D). Overall, the continental crust thins seaward from 27 km to 21 km within the continental shelf across the Zhu I Depression and Dongsha Rise, with slight local thickening beneath the Dongsha Rise accompanying the increase in the Moho depth. The Dongsha Rise is also characterized by 4-7 km thick high-velocity layer (HVL) ( 7.0-7.6 km/s) in the lower crust and exhibits a relatively high velocity ( 5.5-6.4 km/s) in the upper crust with a velocity gradient lower than those of the Zhu I Depression and Tainan Basin. Across the continental slope and continent-ocean transition (COT), which contain the Tainan Basin, the crust sharply thins from 20 km to 10 km seaward and a 2-3 km thick HVL is imaged in the lower crust. We observed that volcanoes are located only within the COT, but none exist in the continental shelf; the Dongsha Rise exhibits a high magnetic anomaly zone and different geochemical characteristics from the COT. Based on those observations, we conclude that the HVL underlying the COT is probably extension related resulting from the decompression melting in the Cenozoic, whereas the HVL beneath the Dongsha Rise is probably arc related and associated with the subduction of the paleo-Pacific plate. These findings are inconsistent with those of some previous studies.

Seismic investigation of an ocean-continent transition zone in the northern South China Sea

NASA Astrophysics Data System (ADS)

Zhu, J.; Qiu, X.; Xu, H.; Zhan, W.; Sun, Z.

2011-12-01

Rifted continental margins and basins are mainly formed by the lithospheric extension. Thined lithosphere of passive continental margins results in decompression melt of magma and created oceanic crust and thined ocean-continent transition (OCT) zone. Two refraction profiles used ocean bottom seismometers deployed in the broad continental shelf and three multi-channel seismic reflection lines in the northern South China Sea, acquired by the ship "Shiyan 2" of the South China Sea Institute of Oceanology, Chinese Academy of Sciences in 2010, are processed and interpreted in this study. Seismic reflection lines cut through the Dongsha rise, Zhu-1 and Zhu-2 depression within a Tertiary basin, Pear River Mouth basin (called as Zhujiangkou basin). These tectonic features are clear imaged in the seismic reflection records. Numerous normal faults, cutted through the basement and related to the stretch of the northern South China Sea margin, are imaged and interpreted. Reflection characteristics of the ocean-continent transition (OCT) zone are summaried and outlined. The COT zone is mainly divided into the northern syn-rift subsidence zone, central volcano or buried volcano uplift zone and tilt faulted block near the South Chia Sea basin. Compared to the previous seismic reflection data and refraction velocity models, the segmentation range of the OCT zone is outlined, from width of about 225 km in the northeastern South China Sea , of 160 km in the central to of 110 km in the north-central South China Sea. Based on the epicenter distribution of sporadic and large than 6 magnitude earthquakes, it suggests the OCT zone in the northern South China Sea at present is still an active seismic zone.

Physical Processes Governing Atmospheric Trace Constituents Measured from an Aircraft on PEM-Tropics

NASA Technical Reports Server (NTRS)

Newell, Reginald E.; Hoell, James M., Jr. (Technical Monitor)

2001-01-01

Before the mission, the PI (principal investigator) was instrumental in securing real-time use of the new 51-level ECMWF (European Centre for Medium Range Weather Forecasts) meteorological data. During the mission, he provided flight planning and execution guidance as meteorologist for the P-3B. Mr. Yong Zhu computed and plotted meteorological forecast maps using the ECMWF data and transmitted them to the field from MIT (Massachusetts Institute of Technology). Dr. John Cho was in the field for the Christmas Island portion to extract data from the on-site NOAA (National Oceanic and Atmospheric Administration) radars for local wind profiles that were used at the flight planning meetings. When the power supply for the VHF radar failed, he assisted the NOAA engineer in its repair. After the mission, Mr. Zhu produced meteorological data memos, which were made available to the PEM (Pacific Exploratory Mission)-Tropics B science team on request. An undergraduate student, Ms. Danielle Morse, wrote memos annotating the cloud conditions seen on the aircraft external monitor video tapes. Dr. Cho and the PI circulated a memo regarding the status (and associated problems) of the meteorological measurement systems on the DC-8 and P-3B to the relevant people on the science team. Several papers by members of our project were completed and accepted by JGR (Journal of Geophysical Research) for the first special section on PEM-Tropics B. These papers included coverage of the following topics: 1) examination of boundary layer data; 2) water vapor transport; 3) tropospheric trace constituent layers; 4) summarizations of the meteorological background and events during PEM-Tropics B; 5) concomitant lidar measurements of ozone, water vapor, and aerosol.

Observation model and parameter partials for the JPL VLBI parameter estimation software MODEST/1991

NASA Technical Reports Server (NTRS)

Sovers, O. J.

1991-01-01

A revision is presented of MASTERFIT-1987, which it supersedes. Changes during 1988 to 1991 included introduction of the octupole component of solid Earth tides, the NUVEL tectonic motion model, partial derivatives for the precession constant and source position rates, the option to correct for source structure, a refined model for antenna offsets, modeling the unique antenna at Richmond, FL, improved nutation series due to Zhu, Groten, and Reigber, and reintroduction of the old (Woolard) nutation series for simulation purposes. Text describing the relativistic transformations and gravitational contributions to the delay model was also revised in order to reflect the computer code more faithfully.

Semi-analytic valuation of stock loans with finite maturity

NASA Astrophysics Data System (ADS)

Lu, Xiaoping; Putri, Endah R. M.

2015-10-01

In this paper we study stock loans of finite maturity with different dividend distributions semi-analytically using the analytical approximation method in Zhu (2006). Stock loan partial differential equations (PDEs) are established under Black-Scholes framework. Laplace transform method is used to solve the PDEs. Optimal exit price and stock loan value are obtained in Laplace space. Values in the original time space are recovered by numerical Laplace inversion. To demonstrate the efficiency and accuracy of our semi-analytic method several examples are presented, the results are compared with those calculated using existing methods. We also present a calculation of fair service fee charged by the lender for different loan parameters.

Comment on "How the huge energy of quantum vacuum gravitates to drive the slow accelerating expansion of the Universe"

NASA Astrophysics Data System (ADS)

Mazzitelli, Francisco D.; Trombetta, Leonardo G.

2018-03-01

In a recent paper [Q. Wang, Z. Zhu, and W. G. Unruh, Phys. Rev. D 95, 103504 (2017), 10.1103/PhysRevD.95.103504] it was argued that, due to the fluctuations around its mean value, vacuum energy gravitates differently from what was previously assumed. As a consequence, the Universe would accelerate with a small Hubble expansion rate, solving the cosmological constant and dark energy problems. We point out here that the results depend on the type of cutoff used to evaluate the vacuum energy. In particular, they are not valid when one uses a covariant cutoff such that the zero-point energy density is positive definite.

Quantum Teleportation of an Arbitrary N-qubit State via GHZ-like States

NASA Astrophysics Data System (ADS)

Zhang, Bo; Liu, Xing-tong; Wang, Jian; Tang, Chao-jing

2016-03-01

Recently Zhu (Int. J. Theor. Phys. 53, 4095, 2014) had shown that using GHZ-like states as quantum channel, it is possible to teleport an arbitrary unknown two-qubit state. We investigate this channel for the teleportation of an arbitrary N-qubit state. The strict proof through mathematical induction is presented and the rule for the receiver to reconstruct the desired state is explicitly derived in the most general case. We also discuss that if a system of quantum secret sharing of classical message is established, our protocol can be transformed to a N-qubit perfect controlled teleportation scheme from the controller's point of view.

Continuum limit of electrostatic gyrokinetic absolute equilibrium

NASA Astrophysics Data System (ADS)

Zhu, Jian-Zhou

2012-06-01

Electrostatic gyrokinetic absolute equilibria with continuum velocity field are obtained through the partition function and through the Green function of the functional integral. The new results justify and explain the prescription for quantization/discretization or taking the continuum limit of velocity. The mistakes in the Appendix D of our earlier work [J.-Z. Zhu and G. W. Hammett, Phys. Plasmas 17, 122307 (2010)] are explained and corrected. If the lattice spacing for discretizing velocity is big enough, all the invariants could concentrate at the lowest Fourier modes in a negative-temperature state, which might indicate a possible variation of the dual cascade picture in 2D plasma turbulence.

The color red reduces snack food and soft drink intake.

PubMed

Genschow, Oliver; Reutner, Leonie; Wänke, Michaela

2012-04-01

Based on evidence that the color red elicits avoidance motivation across contexts (Mehta & Zhu, 2009), two studies investigated the effect of the color red on snack food and soft drink consumption. In line with our hypothesis, participants drank less from a red labeled cup than from a blue labeled cup (Study 1), and ate less snack food from a red plate than from a blue or white plate (Study 2). The results suggest that red functions as a subtle stop signal that works outside of focused awareness and thereby reduces incidental food and drink intake. Copyright © 2012 Elsevier Ltd. All rights reserved.

Can we still beat "buy-and-hold" for individual stocks?

NASA Astrophysics Data System (ADS)

Hui, Eddie C. M.; Kevin Chan, Ka Kwan

2014-09-01

Many investors seek for a trading strategy to beat the "buy-and-hold" strategy. In light of this, Hui and Yam (2014) and Hui et al. (2014) derived a trading strategy from the Shiryaev-Zhou index, and found that the resulting strategy outperformed the "buy-and-hold" strategy for western and Asian securitized real estate indices respectively. However, whether the trading strategy works on individual stocks or not is still unknown. This is the first study to test whether the trading strategy can beat the "buy-and-hold" strategy on individual stocks. We construct two trading strategies and compare the resulting profits with the profits arising from the "buy-and-hold" strategy on Hang Seng Index (HSI), Hang Seng Property (HSP) Index and 12 constituent stocks of HSI during the period December 29, 1995-December 31, 2013. The second strategy (Strategy 2) is a new strategy which incorporates short-selling, and has the effect of multiplying the profit. The results show that our trading strategies are less effective on individual stocks than on stock indices, and are more effective on property stocks than on non-property stocks. Moreover, our strategies outperform "buy-and-hold" by a larger extent on stocks of which the Shiryaev-Zhou indices fluctuate less frequently. Furthermore, by tracking the resulting profits of the three strategies at different times along the whole period of observation, our strategies work better during "bad times" than during "good times". This reflects that our trading strategies are especially useful in protecting investors from substantial loss during market downturns.

Increase in left liver lobe function after preoperative right portal vein embolisation assessed with gadolinium-EOB-DTPA MRI.

PubMed

Geisel, Dominik; Lüdemann, Lutz; Keuchel, Thomas; Malinowski, Maciej; Seehofer, Daniel; Stockmann, Martin; Hamm, Bernd; Gebauer, Bernhard; Denecke, Timm

2013-09-01

To prospectively evaluate the early development of regional liver function after right portal vein embolisation (PVE) with Gd-EOB-DTPA-enhanced MRI in patients scheduled for extended right hemihepatectomy. Ten patients who received a PVE before an extended hemihepatectomy were examined before and 14 days after PVE using Gd-EOB-DTPA-enhanced MRI of the liver. In these sequences representative region of interest measurements were performed in the embolised right (RLL) and the non-embolised left liver lobe (LLL). The volume as well as hepatic uptake index (HUI) was calculated independently for each lobe. Relative enhancement 14 days after PVE decreased in the RLL and increased significantly in the LLL (P < 0.05). Average hepatic uptake index (HUI) for RLL was significantly lower 14 days after PVE than before PVE (P < 0.05) and significantly higher for LLL (P < 0.05). A significant shift of contrast uptake from the right to the left liver lobe can be depicted as early as 14 days after right PVE by using Gd-EOB-DTPA-enhanced MRI, which could reflect the redirected portal venous blood flow and the rapid utilisation of a hepatic functional reserve. • Preoperative portal vein embolisation (PVE) is widely performed before right-sided hepatic resection. • PVE increases intravenous contrast medium uptake in the left lobe of liver. • The hepatic uptake index for the left liver lobe increases rapidly after PVE. • Left liver lobe function increase may be visualised by Gd-EOB-DTPA-enhanced MRI.

Comparison of CME radial velocities from a flux rope model and an ice cream cone model

NASA Astrophysics Data System (ADS)

Kim, T.; Moon, Y.; Na, H.

2011-12-01

Coronal Mass Ejections (CMEs) on the Sun are the largest energy release process in the solar system and act as the primary driver of geomagnetic storms and other space weather phenomena on the Earth. So it is very important to infer their directions, velocities and three-dimensional structures. In this study, we choose two different models to infer radial velocities of halo CMEs since 2008 : (1) an ice cream cone model by Xue et al (2005) using SOHO/LASCO data, (2) a flux rope model by Thernisien et al. (2009) using the STEREO/SECCHI data. In addition, we use another flux rope model in which the separation angle of flux rope is zero, which is morphologically similar to the ice cream cone model. The comparison shows that the CME radial velocities from among each model have very good correlations (R>0.9). We will extending this comparison to other partial CMEs observed by STEREO and SOHO.

Optical quasi-soliton solutions for higher-order nonlinear Schrödinger equation with variable coefficients

NASA Astrophysics Data System (ADS)

Zhang, Jiefang; Yang, Qin; Dai, Chaoqing

2005-04-01

Optical quasi-soliton solutions for higher-order nonlinear Schrödinger equation (HNLS) with variable coefficients are considered. Based on the extended tanh-function method, we successfully obtained bright and dark quasi-soliton solutions under certain parametric conditions. We conclude that the parameter k(z) is unnecessary to be zero compared with [R. Yang et al., Opt. Commun. 242 (2004) 285]. Furthermore, we choose appropriate optical fiber parameters D2(z) and D3(z) to control the velocity of quasi-soliton and time shift, and discuss the evolution behavior of the special quasi-soliton. For D3(z) = α(z) = f(z) = 0, that is to say, under the absence of the higher order terms, we give same results as early reported in [R.Y. Hao, L. Li, Z.H. Li, W.R. Xue, G.S. Zhou, Opt. Commun. 236 (2004) 79]. As discussed examples, we also analyze three optical systems with real physical significance and obtain results which can be recovered in earlier papers.

Le TERS, ou comment obtenir une signature chimique à l'échelle nanométrique

NASA Astrophysics Data System (ADS)

Hsia, Patrick; Chaigneau, Marc

2018-02-01

Le TERS pour tip enhanced raman scattering, est une technique de pointe (dans tous les sens du terme) basée sur l'amplification du signal Raman relative à la résonance de plasmons de surface. Cette technique non-destructive, qui ne nécessite pas de marquage particulier, permet de caractériser un échantillon à l'échelle nanométrique. Le TERS s'impose aujourd'hui pour sonder les propriétés physico-chimiques des nanomatériaux et participer ainsi au développement de nouvelles applications dans le domaine des nanotechnologies.

Chinese medicine patterns in patients with post-stroke dementia.

PubMed

Tang, Nou-Ying; Liu, Chung-Hsiang; Liu, Hsu-Jan; Li, Tsai-Chung; Liu, Jui-Chen; Chen, Ping-Kun; Hsieh, Ching-Liang

2012-04-01

A stroke often results in post-stroke dementia, a rapid decline in memory and intelligence causing dysfunctions in daily life. The Chinese medicine doctor uses 4 examinations of inspection, listening, smelling, and feeling to determine the Chinese medicine pattern (CMP). Therefore, the purpose of the present study was to investigate the CMP in patients with post-stroke dementia. A total of 101 stroke patients were examined, consistent with the DSM IV diagnostic criteria of the American Psychiatric Association, as well as the National Institute of Neurological Disorders and Stroke-Association International pour Ia Recherche et I'Enseignement en Neurosciences vascular dementia diagnostic criteria of post-stroke dementia. 100 patients (99.0%) were KEDP (kidney essence deficiency pattern, shèn jīng kuī xū zhèng, ), 83 patients were AHLYP (ascendant hyperactivity of liver yang pattern, gān yáng shàng kàng zhèng, ), 83 patients were QBDP (qi-blood deficiency pattern, qì xuè kuī xū zhèng, ), 81 patients were SBOCP (static blood obstructing the collaterals pattern, yū xuè zǔ luò zhèng, ), 72 patients were BSTRP (bowels stagnation turbidity retention pattern, fǔ zhì zhuó liú zhèng, ), 50 patients were FHIEP (fire heat interior excess pattern, huǒ rè nèi sheng zhèng, ), and 39 participants (38.6%) were PTOOP (phlegm turbidity obstructing the orifices pattern, tán zhuó zǔ qiào zhèng, ); one to 31 patients have at least 2 CMPs simultaneously. In conclusion, the most CMP is KEDP CMP in the post-stroke dementia patients, and one patient may have one or at least 2 CMPs simultaneously.

Full moment tensor and source location inversion based on full waveform adjoint method

NASA Astrophysics Data System (ADS)

Morency, C.

2012-12-01

The development of high-performance computing and numerical techniques enabled global and regional tomography to reach high levels of precision, and seismic adjoint tomography has become a state-of-the-art tomographic technique. The method was successfully used for crustal tomography of Southern California (Tape et al., 2009) and Europe (Zhu et al., 2012). Here, I will focus on the determination of source parameters (full moment tensor and location) based on the same approach (Kim et al, 2011). The method relies on full wave simulations and takes advantage of the misfit between observed and synthetic seismograms. An adjoint wavefield is calculated by back-propagating the difference between observed and synthetics from the receivers to the source. The interaction between this adjoint wavefield and the regular forward wavefield helps define Frechet derivatives of the source parameters, that is, the sensitivity of the misfit with respect to the source parameters. Source parameters are then recovered by minimizing the misfit based on a conjugate gradient algorithm using the Frechet derivatives. First, I will demonstrate the method on synthetic cases before tackling events recorded at the Geysers. The velocity model used at the Geysers is based on the USGS 3D velocity model. Waveform datasets come from the Northern California Earthquake Data Center. Finally, I will discuss strategies to ultimately use this method to characterize smaller events for microseismic and induced seismicity monitoring. References: - Tape, C., Q. Liu, A. Maggi, and J. Tromp, 2009, Adjoint tomography of the Southern California crust: Science, 325, 988992. - Zhu, H., Bozdag, E., Peter, D., and Tromp, J., 2012, Structure of the European upper mantle revealed by adjoint method: Nature Geoscience, 5, 493-498. - Kim, Y., Q. Liu, and J. Tromp, 2011, Adjoint centroid-moment tensor inversions: Geophys. J. Int., 186, 264278. Prepared by LLNL under Contract DE-AC52-07NA27344.

Transcriptomic analysis of adaptive mechanisms in response to sudden salinity drop in the mud crab, Scylla paramamosain.

PubMed

Wang, Huan; Tang, Lei; Wei, Hongling; Lu, Junkai; Mu, Changkao; Wang, Chunlin

2018-05-31

Scylla paramamosain (Crustacea: Decapoda: Portunidae: Syclla De Hann) is a commercially important mud crab distributed along the coast of southern China and other Indo-Pacific countries (Lin Z, Hao M, Zhu D, et al, Comp Biochem Physiol B Biochem Mol Biol 208-209:29-37, 2017; Walton ME, Vay LL, Lebata JH, et al, Estuar Coast Shelf Sci 66(3-4):493-500, 2006; Wang Z, Sun B, Zhu F, Fish Shellfish Immunol 67:612-9, 2017). While S. paramamosain is a euryhaline species, a sudden drop in salinity induces a negative impact on growth, molting, and reproduction, and may even cause death. The mechanism of osmotic regulation of marine crustaceans has been recently under investigation. However, the mechanism of adapting to a sudden drop in salinity has not been reported. In this study, transcriptomics analysis was conducted on the gills of S. paramamosain to test its adaptive capabilities over 120 h with a sudden drop in salinity from 23 ‰ to 3 ‰. At the level of transcription, 135 DEGs (108 up-regulated and 27 down-regulated) annotated by NCBI non-redundant (nr) protein database were screened. GO analysis showed that the catalytic activity category showed the most participating genes in the 24 s-tier GO terms, indicating that intracellular metabolic activities in S. paramamosain were enhanced. Of the 164 mapped KEGG pathways, seven of the top 20 pathways were closely related to regulation of the Na + / K + -ATPase. Seven additional amino acid metabolism-related pathways were also found, along with other important signaling pathways. Ion transport and amino acid metabolism were key factors in regulating the salinity adaptation of S. paramamosain in addition to several important signaling pathways.

Accuracy assessment of pharmacogenetically predictive warfarin dosing algorithms in patients of an academic medical center anticoagulation clinic.

PubMed

Shaw, Paul B; Donovan, Jennifer L; Tran, Maichi T; Lemon, Stephenie C; Burgwinkle, Pamela; Gore, Joel

2010-08-01

The objectives of this retrospective cohort study are to evaluate the accuracy of pharmacogenetic warfarin dosing algorithms in predicting therapeutic dose and to determine if this degree of accuracy warrants the routine use of genotyping to prospectively dose patients newly started on warfarin. Seventy-one patients of an outpatient anticoagulation clinic at an academic medical center who were age 18 years or older on a stable, therapeutic warfarin dose with international normalized ratio (INR) goal between 2.0 and 3.0, and cytochrome P450 isoenzyme 2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) genotypes available between January 1, 2007 and September 30, 2008 were included. Six pharmacogenetic warfarin dosing algorithms were identified from the medical literature. Additionally, a 5 mg fixed dose approach was evaluated. Three algorithms, Zhu et al. (Clin Chem 53:1199-1205, 2007), Gage et al. (J Clin Ther 84:326-331, 2008), and International Warfarin Pharmacogenetic Consortium (IWPC) (N Engl J Med 360:753-764, 2009) were similar in the primary accuracy endpoints with mean absolute error (MAE) ranging from 1.7 to 1.8 mg/day and coefficient of determination R (2) from 0.61 to 0.66. However, the Zhu et al. algorithm severely over-predicted dose (defined as >or=2x or >or=2 mg/day more than actual dose) in twice as many (14 vs. 7%) patients as Gage et al. 2008 and IWPC 2009. In conclusion, the algorithms published by Gage et al. 2008 and the IWPC 2009 were the two most accurate pharmacogenetically based equations available in the medical literature in predicting therapeutic warfarin dose in our study population. However, the degree of accuracy demonstrated does not support the routine use of genotyping to prospectively dose all patients newly started on warfarin.

[Chemical forms and ecological effect of soil Mn in liver cancer's high incidence area in Zhu-jiang River Delta, China].

PubMed

Dou, Lei; Zhou, Yong-Zhang; Li, Yong; Ma, Jin; An, Yan-Fei; Du, Hai-Yan; Li, Zhan-Qiang

2008-06-01

The samples of surface soil, deep soil, and vegetables were collected from the liver cancer's high- and low incidence areas in Zhujiang River Delta to study the relationships between soil Mn forms and vegetables' Mn enrichment. The results showed that the soil Mn in study area was mainly derived from parent materials, and rarely come from human activities. The average soil Mn content in liver cancer's high incidence area was 577.65 mg x kg(-1), being significantly lower than that of liver cancer's low incidence area (718.04 mg x kg(-1)) and whole country (710 mg x kg(-1)). The Mn forms in high incidence area were mainly of residual Mn and Fe-Mn oxide, and less of water soluble Mn and exchangeable Mn, with the sum of the latter two's distribution coefficients being not higher than 4%. In low incidence area, the distribution pattern of soil Mn forms was similar to that in high incidence area, but the absolute contents of the Mn forms were significantly higher. Soil total Mn and soil pH had significant effects on soil Mn forms. There existed significant positive correlations between soil total Mn and the Mn forms of Fe-Mn bound, humic acid bound, carbonate bound, and residual, and negative correlations between soil pH and soil water soluble and organic bound Mn forms. Among the test five kinds of vegetables, Youmai lettuce and Chinese cabbage in liver cancer' s high incidence area had a significantly lower Mn content than in low incidence area, while the other three had less difference. The Mn enrichment in test vegetables was positively correlated with to the content of soil available Mn (sum of water soluble Mn and exchangeable Mn), but had no correlations with the contents of soil total Mn and other Mn forms.

Two dimensional disorder in black phosphorus and layered monochalcogenides

NASA Astrophysics Data System (ADS)

Barraza-Lopez, Salvador; Mehboudi, Mehrshad; Kumar, Pradeep; Harriss, Edmund O.; Churchill, Hugh O. H.; Dorio, Alex M.; Zhu, Wenjuan; van der Zande, Arend; Pacheco Sanjuan, Alejandro A.

The degeneracies of the structural ground state of materials with a layered orthorhombic structure such as black phosphorus and layered monochalcogenides GeS, GeSe, SnS, and SnSe, lead to an order/disorder transition in two dimensions at finite temperature. This transition has consequences on applications based on these materials requiring a crystalline two-dimensional structure. Details including a Potts model that explains the two-dimensional transition, among other results, will be given in this talk. References: M. Mehboudi, A.M. Dorio, W. Zhu, A. van der Zande, H.O.H. Churchill, A.A. Pacheco Sanjuan, E.O.H. Harris, P. Kumar, and S. Barraza-Lopez. arXiv:1510.09153.

Linear transformation and oscillation criteria for Hamiltonian systems

NASA Astrophysics Data System (ADS)

Zheng, Zhaowen

2007-08-01

Using a linear transformation similar to the Kummer transformation, some new oscillation criteria for linear Hamiltonian systems are established. These results generalize and improve the oscillation criteria due to I.S. Kumari and S. Umanaheswaram [I. Sowjaya Kumari, S. Umanaheswaram, Oscillation criteria for linear matrix Hamiltonian systems, J. Differential Equations 165 (2000) 174-198], Q. Yang et al. [Q. Yang, R. Mathsen, S. Zhu, Oscillation theorems for self-adjoint matrix Hamiltonian systems, J. Differential Equations 190 (2003) 306-329], and S. Chen and Z. Zheng [Shaozhu Chen, Zhaowen Zheng, Oscillation criteria of Yan type for linear Hamiltonian systems, Comput. Math. Appl. 46 (2003) 855-862]. These criteria also unify many of known criteria in literature and simplify the proofs.

Decay of the 3D inviscid liquid-gas two-phase flow model

NASA Astrophysics Data System (ADS)

Zhang, Yinghui

2016-06-01

We establish the optimal {Lp-L2(1 ≤ p < 6/5)} time decay rates of the solution to the Cauchy problem for the 3D inviscid liquid-gas two-phase flow model and analyze the influences of the damping on the qualitative behaviors of solution. Compared with the viscous liquid-gas two-phase flow model (Zhang and Zhu in J Differ Equ 258:2315-2338, 2015), our results imply that the friction effect of the damping is stronger than the dissipation effect of the viscosities and enhances the decay rate of the velocity. Our proof is based on Hodge decomposition technique, the {Lp-L2} estimates for the linearized equations and an elaborate energy method.

Coatings Extend Life of Engines and Infrastructure

NASA Technical Reports Server (NTRS)

2010-01-01

MesoCoat Inc., of Euclid, Ohio, collaborated with Glenn Research Center to provide thermal barrier coating (TBC) technology, developed by Glenn researcher Dongming Zhu, to enhance the lifespan and performance of engines in U.S. Air Force legacy aircraft. The TBC reduces thermal stresses on engine parts, increasing component life by 50 percent. MesoCoat is also producing metal cladding technology that may soon provide similar life-lengthening benefits for the Nation's infrastructure. Through a Space Act Agreement with Glenn, the company employs the Center's high-density infrared arc lamp system to bond its cladding materials for demonstration prototypes; the coating technology can prevent corrosion on metal beams, pipes, and rebar for up to 100 years.

Neonatal treatment philosophy in Dutch and German NICUs: health-related quality of life in adulthood of VP/VLBW infants.

PubMed

Breeman, Linda D; van der Pal, Sylvia; Verrips, Gijsbert H W; Baumann, Nicole; Bartmann, Peter; Wolke, Dieter

2017-04-01

Although survival after very preterm birth (VP)/very low birth weight (VLBW) has improved, a significant number of VP/VLBW individuals develop physical and cognitive problems during their life course that may affect their health-related quality of life (HRQoL). We compared HRQoL in VP/VLBW cohorts from two countries: The Netherlands (n = 314) versus Germany (n = 260) and examined whether different neonatal treatment and rates of disability affect HRQoL in adulthood. To analyse whether cohorts differed in adult HRQoL, linear regression analyses were performed for three HRQoL outcomes assessed with the Health Utilities Index 3 (HUI3), the London Handicap Scale (LHS), and the WHO Quality of Life instrument (WHOQOL-BREF). Stepwise hierarchical linear regression was used to test whether neonatal physical health and treatment, social environment, and intelligence (IQ) were related to VP/VLBW adults' HRQoL and cohort differences. Dutch VP/VLBW adults reported a significantly higher HRQoL on all three general HRQoL measures than German VP/VLBW adults (HUI3: .86 vs .83, p = .036; LHS: .93 vs. .90, p = .018; WHOQOL-BREF: 82.8 vs. 78.3, p < .001). Main predictor of cohort differences in all three HRQoL measures was adult IQ (p < .001). Lower HRQoL in German versus Dutch adults was related to more cognitive impairment in German adults. Due to different policies, German VP/VLBW infants received more intensive treatment that may have affected their cognitive development. Our findings stress the importance of examining effects of different neonatal treatment policies for VP/VLBW adults' life.

[Agro-household livelihood vulnerability and influence factors of ethnic villages under different geomorphology backgrounds.

PubMed

Han, Wen Wen; Liu, Xiao Peng; Pei, Yin Bao; An, Qiong; Li, Yong Hong

2016-04-22

The vulnerability and influence factors of agro-household livelihood in Haiyuan County, Ningxia were empirically analyzed utilizing set pair analysis and obstacle degree model, based on field survey data of impoverished agro-households in 2014. Results showed that vulnerability of agro-household livelihood in Haiyuan County was high in general while it exhibited geomorphological and ethnical differences. Vulnerability of agro-households livelihood in plain areas, valleys and intermountain depression areas were lower than that in earth-rock areas, loess ridge areas and moderately high mountain landform areas. Moreover, vulnerability of agro-household livelihood was higher in mixed Hui and Han ethnic villages than in mono Hui or Han ethnic villages. The villagers' lacking of necessities and the stress of sensitive external geographical environment were considered to be the fundamental reasons of vulnerability of agro-household livelihood. The unreasonable livelihood structure and the unvariant livelihood strategy caused the long-term accumulation of livelihood vulnerabi-lity. The nature of the local environment, which was not easy to change, decreased the accessibility of poverty alleviation resources. Building a clear village water rights allocation system, the implementation of counterpart-assistance to educate impoverished families, increasing investment in improving the diversities of means of living, developing the chains of comprehensive commodity market among villages, were necessary to improve the response capability of agro-household livelihood. The management of vulnerability of agro-household livelihood should put the 'Extending Roads to Every Village Project' on a more prominent position in the 'Extending Radio and TV Broadcasting Coverage to Every Village Project'. Furthermore, the combination of meteorological disaster prevention and insurance enterprise disaster reduction should be sought, and the agricultural production insurance system should be

The Dragon Eyes the Top of the World: Arctic Policy Debate and Discussion in China (China Maritime Study, Number 8)

DTIC Science & Technology

2011-08-01

cites Wu Hui [吴慧], “北极 争 夺 战 的国 际法分析” [Beiji zhengduozhan di guojifa fenxi] [An International Law Analysis of the Battle over the Arctic], 国际关系学院学报...病 X Xuelong 雪龙 Z zhengqu zhanlue 争 取 战 略 Zhongguo Jidi Yanjiu Zhongxin 中国极地研究中心 zhuquan 主权 zhuquan quanli 主权权利 About the Author David...China’s Participation in International Arctic Route Mechanisms,” pp. 99, 102. 14. 王志彬 [Wang Zhibin], “北极引爆世界大 战 ?” [Beiji yinbao shijie dazhan

Les nanostructures pour créer de la couleur, un art inspiré par la nature

NASA Astrophysics Data System (ADS)

Ball, Philip

2018-02-01

Les reflets changeants des plumes de la queue du paon ont captivé plus d'un esprit curieux. Le scientifique anglais Robert Hooke les qualifiait en 1665 de « surnaturelles » en constatant que, mouillées, elles perdaient leurs couleurs. À l'aide du microscope inventé depuis peu, il observa ces plumes, et découvrit qu'elles étaient couvertes de stries - qu'il suspecta d'être à l'origine des couleurs. Aujourd'hui, la recherche tente de s'inspirer de ces phénomènes : des applications « bio-inspirées » sont en voie de concrétisation. ARRAY(0x29ad218)

Integrated Battlefield Effects Research for the National Training Center. Appendix E. Requirements Design Specification and Demonstration Report for the Exercise Coordination and Control (ECC) Demonstration System

DTIC Science & Technology

1984-12-31

mode 3. Edit AAR mode 4. Run AR mode Each of the modes shall be mutually eclusive. In the real-time mode, the station tactical display shall reflect...periods of the exercise segment. The edit AAR mode shall provide the operator with the capability of creating/ editing a command file for use during an...II .,II IH 0 - hUi I -24 .6d, -I" @ 0 M% A A a a dJ a) 6 I I - -- a’ 1.* % 46- 8 ’ 0 "S 8 -- -- "- - I .-36 aISa "S-a:z:-a I I b 0 Il -- I -- I1 -I

Improving the Teleportation Scheme of Three-Qubit State with a Four-Qubit Quantum Channel

NASA Astrophysics Data System (ADS)

Cai, Tao; Jiang, Min

2018-01-01

Recently, Zhao-Hui Wei et al. (Int. J. Theor. Phys. 55, 4687, 2016) proposed an improved quantum teleportation scheme for one three-qubit unknown state with a four-qubit quantum channel based on the original one proposed by Binayak S. Choudhury and Arpan Dhara (Int. J. Theor. Phys. 55, 3393, 2016). According to their schemes, the three-qubit entangled state could be teleported with one four-qubit cluster state and five-qubit joint measurements or four-qubit joint measurements. In this paper, we present an improved protocol only with single-qubit measurements and the same four-qubit quantum channel, lessening the difficulty and intensity of necessary operations.

Geochemical modeling of fluid-fluid and fluid-mineral interactions during geological CO2 storage

NASA Astrophysics Data System (ADS)

Zhu, C.; Ji, X.; Lu, P.

2013-12-01

of reaction coupling is able to reduce the gap between the field and lab rates by about two orders of magnitude at elevated temperatures of 200-300 oC. Currently, we are using Si isotopes as a new tool to unravel the coupled reactions in ambient temperature laboratory experiments. These new experimental data, together with coupled reactive mass transport modeling, will provide more accurate predictions of mineral-fluid interactions in CO2 geological storage. Ji, X. and Zhu C. (2013) Predicting possible effects of H2S impurity on CO2 transportation and geological storage. Environmental Science & Technology. 47, 55-62; Ji, X. and Zhu C. A SAFT Equation of State for the Quaternary H2S-CO2-H2O-NaCl system. Geochimica et Cosmochimica Acta 91, 40-59 Zhu, C., ‡Lu, P., ‡Zheng, Z., Ganor, J., Coupled Alkali Feldspar Dissolution and Secondary Mineral Precipitation in Batch Systems: 4. Numerical modeling of reaction path. Geochimica et Cosmochimica Acta v.74, 3963-3983

Laser control of electronic transitions of wave packet by using quadratically chirped pulses.

PubMed

Zou, Shiyang; Kondorskiy, Alexey; Mil'nikov, Gennady; Nakamura, Hiroki

2005-02-22

An effective scheme is proposed for the laser control of wave packet dynamics. It is demonstrated that by using specially designed quadratically chirped pulses, fast and nearly complete excitation of wave packet can be achieved without significant distortion of its shape. The parameters of the laser pulse can be estimated analytically from the Zhu-Nakamura theory of nonadiabatic transition. If the wave packet is not too narrow or not too broad, then the scheme is expected to be utilizable for multidimensional systems. The scheme is applicable to various processes such as simple electronic excitation, pump-dump, and selective bond breaking, and it is actually numerically demonstrated to work well by taking diatomic and triatomic molecules (LiH, NaK, H(2)O) as examples.

Effect of the counterrotating terms on polarizability in atom-field interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang Dawei; Wang Ligang; Li Aijun

2009-12-15

The effect of the counterrotating terms on the linear polarizability is investigated, which is responsible for the validity of the optical theorem in all frequency regions. A unitary transformation method [H. Zheng, S. -Y. Zhu, and M.S. Zubairy, Rev. Lett. 101, 200404 (2008)] is adopted to overcome the difficulty brought in by the counterrotating terms, which yields a rotating-wave-approximation-like Hamiltonian with modified coupling constant due to the counterrotating terms. A simple expression for the polarizability is obtained, which is a sum of resonant (-) and antiresonant (+) parts, and from which the role of the counterrotating terms and quantum interferencemore » between the counterrotating terms and rotating terms at far off-resonance are discussed.« less

Laser control of electronic transitions of wave packet by using quadratically chirped pulses

NASA Astrophysics Data System (ADS)

Zou, Shiyang; Kondorskiy, Alexey; Mil'nikov, Gennady; Nakamura, Hiroki

2005-02-01

An effective scheme is proposed for the laser control of wave packet dynamics. It is demonstrated that by using specially designed quadratically chirped pulses, fast and nearly complete excitation of wave packet can be achieved without significant distortion of its shape. The parameters of the laser pulse can be estimated analytically from the Zhu-Nakamura theory of nonadiabatic transition. If the wave packet is not too narrow or not too broad, then the scheme is expected to be utilizable for multidimensional systems. The scheme is applicable to various processes such as simple electronic excitation, pump-dump, and selective bond breaking, and it is actually numerically demonstrated to work well by taking diatomic and triatomic molecules (LiH, NaK, H2O) as examples.

Promoting Secondary Analysis of Electronic Medical Records in China: Summary of the PLAGH-MIT Critical Data Conference and Health Datathon.

PubMed

Li, Peiyao; Xie, Chen; Pollard, Tom; Johnson, Alistair Edward William; Cao, Desen; Kang, Hongjun; Liang, Hong; Zhang, Yuezhou; Liu, Xiaoli; Fan, Yong; Zhang, Yuan; Xue, Wanguo; Xie, Lixin; Celi, Leo Anthony; Zhang, Zhengbo

2017-11-14

Electronic health records (EHRs) have been widely adopted among modern hospitals to collect and track clinical data. Secondary analysis of EHRs could complement the traditional randomized control trial (RCT) research model. However, most researchers in China lack either the technical expertise or the resources needed to utilize EHRs as a resource. In addition, a climate of cross-disciplinary collaboration to gain insights from EHRs, a crucial component of a learning healthcare system, is not prevalent. To address these issues, members from the Massachusetts Institute of Technology (MIT) and the People's Liberation Army General Hospital (PLAGH) organized the first clinical data conference and health datathon in China, which provided a platform for clinicians, statisticians, and data scientists to team up and address information gaps in the intensive care unit (ICU). ©Peiyao Li, Chen Xie, Tom Pollard, Alistair Edward William Johnson, Desen Cao, Hongjun Kang, Hong Liang, Yuezhou Zhang, Xiaoli Liu, Yong Fan, Yuan Zhang, Wanguo Xue, Lixin Xie, Leo Anthony Celi, Zhengbo Zhang. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 14.11.2017.

[Analysis on composition principles of prescriptions for stranguria in dictionary of traditional Chinese medicine prescription].

PubMed

Sun, Jing-Chang; Wang, Miao-Miao

2014-03-01

By using traditional Chinese medicine inheritance support system to analyze the dominant experience and recessive principles of the prescriptions for stranguria in the dictionary of traditional Chinese medicine prescription (DCMP), we aim to define the medication pattern and rule and to acquire new prescriptions. In dominant experience analysis, we were able to find 22 drugs used over 50 times, including drugs of clearing heat, diuresis and relieving stranguria which are the most used and drugs of clearing heat, cooling blood, benefiting Qi and nourishing Yin. In addition, drugs of activating Qi and Xue, eliminating phlegm and removing toxic are often used, including 34 herb pairs and 5 combinations of three-taste drugs are used more than 35 times. These results fully reflect the composition principles and compatibility characteristic of prescriptions for treating stranguria in DCMP. Thirteen new prescriptions by way of recessive principle excavating were acquired. These new prescriptions might be suitable to clinical treatments of variable syndromes. This article provides an useful clue to research and produce new drugs.

The Process of Self-Cultivation and the Mandala Model of the Self.

PubMed

Wu, Meiyao

2017-01-01

In his Mandala model of the self, Taiwanese scholar Kwang-Kuo Hwang sees each human being as a combination or intersection of private individual and social person, and also of knowledge and action. To further elaborate the model-with a particular emphasis on teaching/learning, the development of the ideal self and spiritual transcendence-this article will explore the psychological process of self-cultivation in the light of traditional Confucian thinking, which means keeping a balance between inner/outer and self/other. The Neo-Confucian thinker Zhongsha Mou's theories of "the awareness of unexpected developments" and his meditation/cognitive thinking opposition will also be discussed. The analyzed sources will include the traditional Confucian classics (the Four Books and Liji, or Classic of Rites ) and especially the " Lessons for Learning ( Xue-Ji )" in the Classic of Rites ( Liji ), along with the relevant textual research. Based upon a cultural-semantic analysis of these classics as well as of Hwang's central ideas, the author attempts to further conceptualize the process of cultivating the ideal self in Confucian education.

Thermophysical effects of carbon nanotubes on MHD flow over a stretching surface

NASA Astrophysics Data System (ADS)

Ul Haq, Rizwan; Khan, Zafar Hayat; Khan, Waqar Ahmed

2014-09-01

This article is intended for investigating the effects of magnetohydrodynamics (MHD) and volume fraction of carbon nanotubes (CNTs) on the flow and heat transfer in two lateral directions over a stretching sheet. For this purpose, three types of base fluids specifically water, ethylene glycol and engine oil with single and multi-walled carbon nanotubes are used in the analysis. The convective boundary condition in the presence of CNTs is presented first time and not been explored so far. The transformed nonlinear differential equations are solved by the Runge-Kutta-Fehlberg method with a shooting technique. The dimensionless velocity and shear stress are obtained in both directions. The dimensionless heat transfer is determined on the surface. Three different models of thermal conductivity are comparable for both CNTs and it is found that the Xue [1] model gives the best approach to guess the superb thermal conductivity in comparison with the Maxwell [2] and Hamilton and Crosser [3] models. And finally, another finding suggests the engine oil provides the highest skin friction and heat transfer rates.

Filling the gap of existing MWA-VCS archival data

NASA Astrophysics Data System (ADS)

Xue, M.; Bhat, R.; Tremblay, S.; Ord, S.; Sobey, C.; Kirsten, F.

2017-01-01

Since July 2014, around 110 hours of high time resolution voltage data observed by MWA Voltage Capture System (VCS; Tremblay et al. 2015) have been archived on tapes in the Pawsey Supercomputing Centre. Except some short duration test data and calibration data, the total amount of the observation data which have a duration longer than 400 s is 84 hours. These data cover a significant portion of a lot of the Southern sky and could be used for many science purposes including radio pulsars census and fast radio bursts (FRBs) searching. But there are still some 'holes' in the sky that we do not have VCS archival data for yet. We are proposing a set of MWA-VCS drift scan observations of 3 hours to fill some of these 'holes' and help provide a more complete MWA-VCS data set. We will also census known (cataloged) pulsars in these areas. These observations would be performed between 170-200 MHz. This project will form part of the PhD program of Mengyao Xue.

Nonparametric Determination of Redshift Evolution Index of Dark Energy

NASA Astrophysics Data System (ADS)

Ziaeepour, Houri

We propose a nonparametric method to determine the sign of γ — the redshift evolution index of dark energy. This is important for distinguishing between positive energy models, a cosmological constant, and what is generally called ghost models. Our method is based on geometrical properties and is more tolerant to uncertainties of other cosmological parameters than fitting methods in what concerns the sign of γ. The same parametrization can also be used for determining γ and its redshift dependence by fitting. We apply this method to SNLS supernovae and to gold sample of re-analyzed supernovae data from Riess et al. Both datasets show strong indication of a negative γ. If this result is confirmed by more extended and precise data, many of the dark energy models, including simple cosmological constant, standard quintessence models without interaction between quintessence scalar field(s) and matter, and scaling models are ruled out. We have also applied this method to Gurzadyan-Xue models with varying fundamental constants to demonstrate the possibility of using it to test other cosmologies.

The Process of Self-Cultivation and the Mandala Model of the Self

PubMed Central

Wu, Meiyao

2017-01-01

In his Mandala model of the self, Taiwanese scholar Kwang-Kuo Hwang sees each human being as a combination or intersection of private individual and social person, and also of knowledge and action. To further elaborate the model—with a particular emphasis on teaching/learning, the development of the ideal self and spiritual transcendence—this article will explore the psychological process of self-cultivation in the light of traditional Confucian thinking, which means keeping a balance between inner/outer and self/other. The Neo-Confucian thinker Zhongsha Mou's theories of “the awareness of unexpected developments” and his meditation/cognitive thinking opposition will also be discussed. The analyzed sources will include the traditional Confucian classics (the Four Books and Liji, or Classic of Rites) and especially the “Lessons for Learning (Xue-Ji)” in the Classic of Rites (Liji), along with the relevant textual research. Based upon a cultural-semantic analysis of these classics as well as of Hwang's central ideas, the author attempts to further conceptualize the process of cultivating the ideal self in Confucian education1. PMID:28174544

Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect.

PubMed

Lim, Cherry; Wannapinij, Prapass; White, Lisa; Day, Nicholas P J; Cooper, Ben S; Peacock, Sharon J; Limmathurotsakul, Direk

2013-01-01

Estimates of the sensitivity and specificity for new diagnostic tests based on evaluation against a known gold standard are imprecise when the accuracy of the gold standard is imperfect. Bayesian latent class models (LCMs) can be helpful under these circumstances, but the necessary analysis requires expertise in computational programming. Here, we describe open-access web-based applications that allow non-experts to apply Bayesian LCMs to their own data sets via a user-friendly interface. Applications for Bayesian LCMs were constructed on a web server using R and WinBUGS programs. The models provided (http://mice.tropmedres.ac) include two Bayesian LCMs: the two-tests in two-population model (Hui and Walter model) and the three-tests in one-population model (Walter and Irwig model). Both models are available with simplified and advanced interfaces. In the former, all settings for Bayesian statistics are fixed as defaults. Users input their data set into a table provided on the webpage. Disease prevalence and accuracy of diagnostic tests are then estimated using the Bayesian LCM, and provided on the web page within a few minutes. With the advanced interfaces, experienced researchers can modify all settings in the models as needed. These settings include correlation among diagnostic test results and prior distributions for all unknown parameters. The web pages provide worked examples with both models using the original data sets presented by Hui and Walter in 1980, and by Walter and Irwig in 1988. We also illustrate the utility of the advanced interface using the Walter and Irwig model on a data set from a recent melioidosis study. The results obtained from the web-based applications were comparable to those published previously. The newly developed web-based applications are open-access and provide an important new resource for researchers worldwide to evaluate new diagnostic tests.

Preferences for Type 2 Diabetes Health States among Adolescents With or at Risk of Type 2 Diabetes Mellitus

PubMed Central

Rhodes, Erinn T.; Prosser, Lisa A.; Lieu, Tracy A.; Songer, Thomas J.; Ludwig, David S.; Laffel, Lori M.

2015-01-01

Objective We evaluated how adolescents with or at risk of type 2 diabetes (T2DM) and their parent/guardians (parents) value health states associated with T2DM. Methods We interviewed overweight/obese (BMI≥85th percentile), 12–18 year-old adolescents with T2DM, prediabetes, or insulin resistance (IR) and a parent. The standard gamble (SG) method elicited preferences (utilities) for 7 hypothetical T2DM health states reported on a scale from 0 (dead) to 1 (perfect health). Adolescent’s current health was evaluated with the SG and Health Utilities Index (HUI). Results There were 70 adolescents and 69 parents. Adolescents were 67.1% female and 15.5±2.2 years old; 30% had T2DM, 30% prediabetes, and 40% IR. Almost half (48.6%) had a BMI>99th percentile. Parents (83% mothers) were 45.1±7.3 years old and 75% had at least some college/technical school education. Adolescents and parents rated T2DM with no complications treated with diet as most desirable (median [IQR]; adolescent 0.72 [0.54, 0.98]; parent 1.0 [0.88, 1.0]) and end stage renal disease as least desirable (adolescent 0.51 [0.31, 0.70]; parent 0.80 [0.65, 0.94]). However, adolescents’ utilities were significantly lower (p≤0.001) than parents for all health states assessed. Adolescents’ assessment of their current health with the SG and HUI were not correlated. Conclusions Adolescents with or at risk of T2DM rated treatments and sequelae of diabetes as significantly worse than their parents. These adolescent utilities should be considered in the evaluation of treatment strategies for youth with T2DM. Family-based programs for T2DM must also be prepared to address conflicting preferences in order to promote shared-decision making. PMID:21489091

Contribution of Efflux Pumps, Porins, and β-Lactamases to Multidrug Resistance in Clinical Isolates of Acinetobacter baumannii

PubMed Central

Rumbo, C.; Gato, E.; López, M.; Ruiz de Alegría, C.; Fernández-Cuenca, F.; Martínez-Martínez, L.; Vila, J.; Pachón, J.; Cisneros, J. M.; Rodríguez-Baño, J.; Pascual, A.

2013-01-01

We investigated the mechanisms of resistance to carbapenems, aminoglycosides, glycylcyclines, tetracyclines, and quinolones in 90 multiresistant clinical strains of Acinetobacter baumannii isolated from two genetically unrelated A. baumannii clones: clone PFGE-ROC-1 (53 strains producing the OXA-58 β-lactamase enzyme and 18 strains with the OXA-24 β-lactamase) and clone PFGE-HUI-1 (19 strains susceptible to carbapenems). We used real-time reverse transcriptase PCR to correlate antimicrobial resistance (MICs) with expression of genes encoding chromosomal β-lactamases (AmpC and OXA-51), porins (OmpA, CarO, Omp33, Dcap-like, OprB, Omp25, OprC, OprD, and OmpW), and proteins integral to six efflux systems (AdeABC, AdeIJK, AdeFGH, CraA, AbeM, and AmvA). Overexpression of the AdeABC system (level of expression relative to that by A. baumannii ATCC 17978, 30- to 45-fold) was significantly associated with resistance to tigecycline, minocycline, and gentamicin and other biological functions. However, hyperexpression of the AdeIJK efflux pump (level of expression relative to that by A. baumannii ATCC 17978, 8- to 10-fold) was significantly associated only with resistance to tigecycline and minocycline (to which the TetB efflux system also contributed). TetB and TetA(39) efflux pumps were detected in clinical strains and were associated with resistance to tetracyclines and doxycycline. The absence of the AdeABC system and the lack of expression of other mechanisms suggest that tigecycline-resistant strains of the PFGE-HUI-1 clone may be associated with a novel resistance-nodulation-cell efflux pump (decreased MICs in the presence of the inhibitor Phe-Arg β-naphthylamide dihydrochloride) and the TetA(39) system. PMID:23939894

Haplotype analysis of the polymorphic 40 Y-STR markers in Chinese populations.

PubMed

Ou, Xueling; Wang, Ying; Liu, Chao; Yang, Donggui; Zhang, Chuchu; Deng, Shujiao; Sun, Hongyu

2015-11-01

Forty Y-STR loci were analyzed in 1128 males from the following six Chinese ethnic populations: Han (n=300), Hui (n=244), Korean (n=100), Mongolian (n=100), Uighur (n=284) and Tibetan (n=100), utilizing two new generation multiplex Y-STR systems, AGCU Y24 STR and GFS Y24 STR genotyping kits, which allow for the genotyping of 24 loci from a single amplification reaction in each system. The lowest estimates of genetic diversity (below 0.5) correspond to markers DYS391 (0.441658) and DYS437 (0.496977), and the greatest diversity corresponds to markers DYS385a/b (0.969919) and DYS527a/b (0.94676). A considerable number of duplicate and off-ladder alleles were also revealed. Additionally, there were 1111 different haplotypes identified from the total 1128 samples, of which 1095 were unique. Notably, no shared haplotypes between populations were observed. The estimated overall haplotype diversity (HD) was 0.999085, and its discrimination capacity (DC) was 0.970745. An MDS plot based on the genetic distances between populations showed the genetic similarity of the southern Han population to the Northern populations of Hui, Korean, Mongolian and Uighur and a clear genetic departure of the Tibetan population from other populations. For the Y STR markers, population substructure correction was considered when calculating the rarity of the Y STR profile. However, because the haplotype based Fst values are extremely small within the present data (0.000153 with 40 Y-STRs), no substructure correction is required to estimate the rarity of a haplotype comprising 40 markers. In summary, the results of our study indicate that the 40 Y-STRs have a high level of polymorphism in Chinese ethnic groups and could therefore be a powerful tool for forensic applications and population genetic studies. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Quality of life among children with spina bifida in Uganda.

PubMed

Sims-Williams, Helen J; Sims-Williams, Hugh P; Mbabazi Kabachelor, Edith; Warf, Benjamin C

2017-11-01

Children surviving after spina bifida repair often have significant disability, the consequences of which may be more profound in low-income countries. The aim of this cross-sectional study was to measure quality of life (QOL) reported by children with spina bifida in Uganda, and to define factors associated with QOL. QOL was measured using both the Health Utilities Index (HUI3) Tool and a visual analogue scale (VAS) marked from 0 to 10. In keeping with the WHO definition of QOL, further analysis was conducted using subjective QOL scores (using the VAS). Multivariate regression was used to investigate the association between VAS scores and prespecified variables: age, sex, hydrocephalus, mobility, urinary continence, school attendance and family size. Sixty two of 68 surviving children aged 10-14 were able to complete all aspects of the assessment. There was poor correlation between the VAS and HUI3 Tool (Pearson correlation 0.488). On multivariate regression, the following variables were associated with a significant change in the 10-point VAS (change in score; 95% CI): male sex (-1.45; -2.436 to -0.465), urinary continence (1.681; 0.190 to 3.172), large family size (-1.775; -2.773 to -0.777) and hydrocephalus (-1.382; -2.374 to -0.465). Urinary continence and family size are potentially modifiable, the former by simple and inexpensive medical management. Enhanced investment in community-based rehabilitation and support is urgently needed. Delivery of family planning services is a national priority in Uganda, and should be discussed with families as part of holistic care. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Radiologic advantages of potential use of polymer plastic clips in neurosurgery.

PubMed

Delibegović, Samir

2014-01-01

Plastic clips are made of diamagnetic material and may result in fewer computed tomography (CT) and magnetic resonance artifacts than titanium clips. Considering that polymer plastic clips are increasingly being used in endoscopic surgery, our study examined the CT and magnetic resonance imaging (MRI) characteristics of plastic clips after application in the neurocranium and compared them with titanium clips. Craniotomy was performed on the heads of domestic pigs (Sus scrofa domestica), and, at an angle of 90°, a permanent Yasargil FT 746 T clip was placed in a frontobasal, interhemispheric position. A plastic polymer medium-large Hem-o-lok clip was placed in the same position into another animal. After this procedure, CT of the brain was performed using Siemens 16 slice, followed by an MRI scan, on Philips MRI, 1.5 Tesla. The CT and magnetic resonance scans were analyzed. On axial CT sections through the site of placement of titanium clips, dotted hyperdensity with a high value of Hounsfield units (HUI) of about 2800-3000 could be clearly seen. At the site where the plastic polymer clips were placed, discrete hyperdensity was observed, measuring 130-140 HUI. MRI of the brain in which titanium clips were used revealed a hypointensive T1W signal in the interhemispheric fissure, with a hypointensive T2W signal. On the other hand, upon examination of the MRI of the brain in which plastic clips were used, the T1W signal described above did not occur, and there was also no T2W signal, and no artifacts observed. The plastic clips are made of a diamagnetic, nonconductive material that results in fewer CT and MRI artifacts than titanium clips. Copyright © 2014 Elsevier Inc. All rights reserved.

Whakaora nga moemoea o nga tupuna--living the dreams of the ancestors. Future planning in a Kaupapa Māori CAMHS team.

PubMed

Elder, Hinemoa; Milne, Moe; Witehira, Heemi; Mendes, Patrick; Heslin, Anneliese; Cribb-Su'a, Ainsleigh; Wilson, Riwai; Goldsmith, Arona; Kainamu, Reena; Barrett, Moana; Love, Shar; Cargo, Tania; Kalra, Vanitha

2009-08-01

The aim of this study was to identify and operationalize aspects of a future planning process for sustainable delivery of Kaupapa Māori (Specialist Māori) mental health from a team called He Kakano, within Child and Adolescent Mental Health Services in South Auckland, New Zealand. A 2-day hui (meeting) was held with members of the team and a facilitator, Whaea Moe Milne. Review of background national epidemiological data, local data, information from community, carer and tangata whaiora (consumer) stakeholders and the existing He Kakano Model of Care was undertaken. Use of tikanga (Māori protocol and practices) was evident throughout the hui. A number of aspects of tikanga were identified as essential to the positive outcomes of the future plan. This paper reports one in particular, that of whakatauakī (proverbs where the originator is known). "Whakaora nga moemoea o nga tupuna--living the dreams of the ancestors" is a whakatauakī articulated by Whaea Moe Milne, which was identified as helpful in influencing the strategic planning thinking and decision-making process for He Kakano. This whakatauakī enabled the identification of shared goals, values, beliefs, behaviours and an action plan. The existing and ongoing relationship with Whaea Moe Milne was identified as an important element in the way in which the whakatauakī was received and reflected on. Use of tikanga Māori, in this case, whakatauakī, was helpful in developing future planning for He Kakano. This suggests that use of tikanga may be beneficial in other settings where planning for sustainable Māori responsive services is undertaken. Further work in this area is likely to benefit service development, strategic planning, workforce development and have an impact on improving health outcomes for Māori.

Development of urbanization in arid and semi arid regions based on the water resource carrying capacity -- a case study of Changji, Xinjiang

NASA Astrophysics Data System (ADS)

Xiao, H.; Zhang, L.; Chai, Z.

2017-07-01

The arid and semiarid region in China where have a relatively weak economic foundation, independent development capacity, and the low-level of urbanization. The new urbanization within these regions is facing severe challenges brought by the constraints of resources. In this paper, we selected the Changji Hui Autonomous Prefecture, Xinjiang Uyghur Autonomous Region as study area. We found that agricultural planting structure is the key water consumption index based on the research about the main water demands of domestic, agriculture and industry. Finally, we suggest that more attentions should be paid to the rational utilization of water resources, population carrying capacity, and adjust and upgrade the industrial structure, with the purpose of coordination with the Silk Road Economic Belt.

Effect of activated sludge acclimation aeration time on bayberry wastewater

NASA Astrophysics Data System (ADS)

Shi, Liang; He, Lingfeng; Zhang, Yongli

2018-03-01

Taking the myrica rubra pickle wastewater of Chaozhou Kang Hui group as the water sample, biochemical method was used to treat the wastewater, after domestication, the biochemical treatment was carried out. The influence of time on COD index was investigated. The results showed that: tap water: sewage: sludge = 1:1:1, 900 mL each. Under the action of 30 min time, the supernatant was taken at 100 mL, and the wastewater was added to 900 mL,. Under the action of activated sludge, the degradation of myrica rubra wastewater samples, after domestication 84 h, the effect is better. Under this condition, the standard of SBR process for wastewater treatment is reached.

A new Lagrangian method for three-dimensional steady supersonic flows

NASA Technical Reports Server (NTRS)

Loh, Ching-Yuen; Liou, Meng-Sing

1993-01-01

In this report, the new Lagrangian method introduced by Loh and Hui is extended for three-dimensional, steady supersonic flow computation. The derivation of the conservation form and the solution of the local Riemann solver using the Godunov and the high-resolution TVD (total variation diminished) scheme is presented. This new approach is accurate and robust, capable of handling complicated geometry and interactions between discontinuous waves. Test problems show that the extended Lagrangian method retains all the advantages of the two-dimensional method (e.g., crisp resolution of a slip-surface (contact discontinuity) and automatic grid generation). In this report, we also suggest a novel three dimensional Riemann problem in which interesting and intricate flow features are present.

Total cross sections of electron scattering by molecules NF3, PF3, N(CH3)3, P(CH3)3, NH(CH3)2, PH(CH3)2, NH2CH3 and PH2CH3 at 30-5000 eV

NASA Astrophysics Data System (ADS)

Shi, D. H.; Sun, J. F.; Zhu, Z. L.; Liu, Y. F.

2010-04-01

Total cross sections of electron scattering by eight molecules NF3, PF3, N(CH3)3, P(CH3)3, NH(CH3)2, PH(CH3)2, NH2CH3 and PH2CH3, which have some structural similarities, are calculated at the Hartree-Fork level by the modified additivity rule approach [D.H. Shi, J.F. Sun, Z.L. Zhu, H. Ma, Y.F. Liu, Eur. Phys. J. D 45, 253 (2007); D.H. Shi, J.F. Sun, Y.F. Liu, Z.L. Zhu, X.D. Yang, Chin. Opt. Lett. 4, 192 (2006)]. The modified additivity rule approach takes into considerations that the contributions of the geometric shielding effect vary as the energy of incident electrons, the dimension of target molecule, the number of electrons in the molecule and the number of atoms constituting the molecule. The present investigations cover the impact energy range from 30 to 5000 eV. The quantitative total cross sections are compared with those obtained by experiments and other theories. Excellent agreement is observed even at energies of several tens of eV. It shows that the modified additivity rule approach is applicable to carry out the total cross section calculations of electron scattering by these molecules at intermediate and high energies, in particular over the energy range above 80 eV or so. It proves that the microscopic molecular properties, such as the geometrical size of the target and the number of atoms constituting the molecule, are of crucial importance in the TCS calculations. The new results for PH(CH3)2 and PH2CH3 are also presented at energies from 30 to 5000 eV, although no experimental and theoretical data are available for comparison. In the present calculations, the atoms are still represented by the spherical complex optical potential, which is composed of static, exchange, polarization and absorption terms.

Metagenome-assembled genomes of deep-branching magnetotactic bacteria in the Nitrospirae phylum

NASA Astrophysics Data System (ADS)

Zhang, W.; He, M.; Gu, L.; Tang, X.; Pan, Y.; Lin, W.

2017-12-01

Magnetotactic bacteria (MTB) are aquatic microorganisms that synthesize intracellular magnetic nanoparticles composed of magnetite and/or greigite. MTB have thus far been identified in the phyla of Proteobacteria, Nitrospirae, Omnitrophica, Latescibacteria and Planctomycetes (Lin et al., 2017b). Among these organisms, MTB belonging to the Nitrospirae phylum are of great interest because of the formation of hundreds of magnetite magnetosomes in a single cell and of the great potential for iron, sulfur, nitrogen, and carbon cycling in natural environments. However, due to the lack of genomic information, our current knowledge on magnetotactic Nitrospirae remains very limited. In the present study, we have identified and characterized two novel populations of uncultivated MTB from freshwater lakes in Shaanxi province, China. 16S rRNA gene-based analyses revealed that they belonged to two different clusters in the Nitrospirae. The draft population genomes of these two Nitrospirae MTB were successfully recovered through genome-resolved metagenomics, both of which containing nearly complete magnetosome gene clusters (MGCs) responsible for magnetosome biomineralization and organization. In consistent with our previous study (Lin et al., 2017a), we found that the gene content and gene organization of the MGCs in the Nitrospirae MTB were highly conserved, indicating that Nitrospirae gene clusters represent one of the ancestral types of MGCs. The population genome sequences suggest that magnetotactic Nitrospirae are capable of CO2 fixtion through Wood-Ljungdahl pathway. They may also reduce sulfate and nitrate/nitrite through sulfate reduction pathway and denitrification pathway, respectively. Our genomic analyses revealed the potential metabolic capability of the Nitrospirae MTB and shed light on their ecology, evolution and biomineralization mechanism. References: Lin W, Paterson GA, Zhu Q, Wang Y, Kopylova E, Li Y, Knight R, Bazylinski DA, Zhu R, Kirschvink JL, Pan Y

Decreased risk of stroke in patients receiving traditional Chinese medicine for vertigo: A population-based cohort study.

PubMed

Tsai, Tzung-Yi; Li, Chung-Yi; Livneh, Hanoch; Lin, I-Hsin; Lu, Ming-Chi; Yeh, Chia-Chou

2016-05-26

Patients with vertigo are reported to exhibit a higher risk of subsequent stroke. However, it remains unclear if Traditional Chinese Medicine (TCM), the most common form of complementary and alternative medicine, can help lower the risk of stroke for these patients. So the aim of the study was to investigate the effects of TCM on stroke risk among patients with vertigo. This longitudinal cohort study used the Taiwanese National Health Insurance Research Database to identify 112,458 newly diagnosed vertigo patients aged ≥20 years who received treatment between 1998 and 2007. Among these patients, 53,203 (47.31%) received TCM after vertigo onset (TCM users), and the remaining 59,201 patients were designated as a control group (non-TCM users). All enrollees received follow-up until the end of 2012 to measure stroke incidence. Cox proportional hazards regression was used to compute the hazard ratio (HR) of stroke in recipients of TCM services. During 15-year follow-up, 5532 TCM users and 12,295 non-TCM users developed stroke, representing an incidence rate of 13.10% and 25.71% per 1000 person-years. TCM users had a significantly reduced risk of stroke compared to non-TCM users (adjusted HR=0.64; 95% confidence interval CI=0.59-0.74). The predominant effect was observed for those receiving TCM for more than 180 days (adjusted HR=0.52; 95% CI=0.49-0.56). Commonly used TCM formulae, including Ban-Xia-Bai-Zhu-Tian-Ma-Tang, Ling-Gui-Zhu-Gan-Tang, Bai Zhi (Angelica dahurica (Hoffm.) Benth. & Hook.f. ex Franch. & Sav., root), Ge Gen (Pueraria lobata (Willd.) Ohwi, root) and Hai Piao Xiao (Endoconcha Sepiae, Cuttlefish Bone) were significantly associated with lower risk of stroke. Results of this population-based study support the effects of TCM on reducing stroke risk, and may provide a reference for stroke prevention strategies. The study results may also help to integrate TCM into clinical intervention programs that provide a favorable prognosis for vertigo patients

Three spider species of the genus Mimetus Hentz, 1832 (Araneae, Mimetidae) from China

PubMed Central

Zeng, Chen; Wang, Cheng; Peng, Xian-Jin

2016-01-01

Abstract The present paper deals with three species of the genus Mimetus from China, including Mimetus echinatus Wang, 1990, Mimetus lamelliformis sp. n. (male), and Mimetus wangi sp. n. (female and male). Mimetus lamelliformis differs from the related species Mimetus echinatus Wang, 1990 by: cymbial tip with several slender long macrosetae; cymbium boat-shaped, length/width ratio about 3/1 in retrolateral view; vexillum about 1/2 length of cymbium in retrolateral view. Mimetus wangi sp. n. differs from the related species Mimetus sinicus Song & Zhu, 1993 by: the opisthosoma with a pair of distinct outgrowths in the dorsum; sperm duct nearly horizontal; spermathecae kidney shaped and contiguous. Photos of body and copulatory organs, line drawings of copulatory organs, as well as the locality map are provided. PMID:27833436

Thermoelectric transport properties of nanostructured FeSb 2 and Ce-based heavy-fermions CeCu and CeAl 3

NASA Astrophysics Data System (ADS)

Pokharel, Mani R.

the thermal conductivities of nanostructured FeSb2 samples 7. We find a notably large value for Kapitza length at low temperatures indicating the dominance of inter-grain thermal resistance over bulk thermal resistance in determining the thermal properties of FeSb 2. 1Huaizhou Zhao, Mani Pokharel, Gaohua Zhu, Shuo Chen, Kevin Lukas, Qing Jie,Cyril Opeil, Gang Chen, and Zhifeng Ren, Appl. Phys. Lett. 99, 163101 (2011). 2Mani Pokharel, Tulashi Dahal, Zhifeng Ren, and Cyril Opeil, Journal of Alloys and Compounds 609 (2014) 228-232. 3Mani Pokharel, Tulashi Dahal, Zhensong Ren, Peter Czajka, Stephen Wilson, Zhifeng Ren, and Cyril Opeil, Energy Conversion and Management, 87 (2014) 584-588. 4Mani Pokharel, Machhindra Koirala, Huaizhau Zhao, Zhifeng Ren, and Cyril Opeil, J. Low Temp. Phys., 176 (2014) 122-130. 5Mani Pokharel, Huaizhou Zhao, Shuo Chen, Kevin Lukas, Hui Wang, Cyril Opeil1, Gang Chen, and Zhifeng Ren, Nanotechnology 23 (2012) 505402. 6Mani Pokharel, Huaizhou Zhao, Kevin Lukas, Bogdan Mihaila, Zhifeng Ren, and Cyril Opeil, MRS Communications 3 (2013) 31-36. 7Mani Pokharel, Huaizhau Zhao, Zhifeng Ren, and Cyril Opeil, International Journal of Thermal Science, 71 (2013) 32-35.

The "Pseudocommando" mass murderer: part II, the language of revenge.

PubMed

Knoll, James L

2010-01-01

In Part I of this article, research on pseudocommandos was reviewed, and the important role that revenge fantasies play in motivating such persons to commit mass murder-suicide was discussed. Before carrying out their mass shootings, pseudocommandos may communicate some final message to the public or news media. These communications are rich sources of data about their motives and psychopathology. In Part II of this article, forensic psycholinguistic analysis is applied to clarify the primary motivations, detect the presence of mental illness, and discern important individual differences in the final communications of two recent pseudocommandos: Seung-Hui Cho (Virginia Tech) and Jiverly Wong (Binghamton, NY). Although both men committed offenses that qualify them as pseudocommandos, their final communications reveal striking differences in their psychopathology.

FDA's proposed rules on patent listing requirements for new drug and 30-month stays on ANDA approval (proposed Oct. 24, 2002).

PubMed

Hui, Yuk Fung

2003-01-01

In order to close the loophole in the generic drug approval process that allows a brand name drug patent holder to delay or defeat generic drug application merely by technicality, the FDA recently proposed to modify its regulations. Those proposals affect the patent listing requirements of a new drug application, and the duration of time that a generic drug application could be put on hold in the event of a patent infringement suit. With the modified rules, the FDA expects to see an increase in the availability of generic drugs, which eventually will lead to lower drug costs. Ms. Hui discusses the contents of the proposed regulations and provides an analysis of the proposed rule's legal authority, implications on patent rights, and impact on the pharmaceutical industry.

Eleven new species of Spilogona Schnabl, 1911 (Diptera, Muscidae) from the Altai Mountains of Russia, with key to species.

PubMed

Sorokina, Vera S

2018-04-17

Eleven new Spilogona species: Spilogona altaica sp. nov., Spilogona antoninae sp. nov., Spilogona colorata sp. nov., Spilogona decolorata sp. nov., Spilogona improvisa sp. nov., Spilogona insolita sp. nov., Spilogona longissima sp. nov., Spilogona novgorodovana sp. nov., Spilogona platyfrons sp. nov., Spilogona tanushka sp. nov., Spilogona tara sp. nov. and a key is provided to the 53 species known from the Altai Mountains including 21 species are newly recorded for the Altai, and seven of them also represent new records from Russia: Spilogona meadei (Schnabl, 1915), Spilogona orthosurstyla Xue Tian, 1988, Spilogona placida (Huckett, 1932), Spilogona setigera (Stein, 1907), Spilogona sororcula (Zetterstedt, 1845), Spilogona spinicosta (Stein, 1907), Spilogona stackelbergi Hennig, 1959). And four species represent new records for the Palaearctic Region: Spilogona flavinervis Huckett, 1965, Spilogona imitatrix (Malloch, 1921), Spilogona nutaka Huckett, 1965, Spilogona incerta Huckett, 1965. Three new synonymies are proposed: Spilogona impar (Stein, 1907) = Spilogona deflorata (Holmgren, 1872), Spilogona churchillensis Huckett, 1965 = Spilogona quinquesetosa (Schnabl, 1915), and Spilogona robusta Huckett, 1965 = Spilogona sordidipennis (Holmgren, 1883). The pictures of the new species are given and the male terminalia are figured. New faunistic data are given for some previously described species of Altai Spilogona.

Scientific psychology within the Chinese language and cultural context.

PubMed

Shen, Heyong

2006-01-01

The Scientific Psychology that was founded by Wilhelm Wundt appeared in China in the late nineteenth century. The scholars translated the name of psychology into Chinese as Xin-Li-Xue, for which the meaning of the words looks like "heartology," i.e., "the study of the heart." In Chinese, the same core structure related to "heart" (Xin) is found in most of the terms of psychology, such as emotion, thinking, will, forgetting, and memory. By translating Xin as "heart" instead of "mind," we maintain an embodied approach to understanding the "principles of the heart." Through a historical approach to the influence of Western psychology, a cultural analysis of the meaning of the term psychology in Chinese, and a focus on the meeting of Eastern and Western psychology, we can witness the significance of psychology in the Chinese language and cultural context. I will use three parts to present psychology in the Chinese cultural context: the origins of Chinese psychology, from a historical approach; the meaning of "psychology" in Chinese, using a cultural analysis; and the meeting of Eastern and Western psychology, focusing on the development and future.

[Research on southward spreading of Hejian' Theory in the Yuan Dynasty].

PubMed

Li, Y Q

2017-03-28

Hejian' Theory was flourished in the Dading reign of the Jin Dynasty, while the doctors of the Southern Song Dynasty didn't know Hejian's Theory. As Southern Song was overthrown by the Yuan Dynasty, Hejian' Theory began to spread to the South. Hejian's descendants, disciples and those doctors studied this Theory personally all contributed to the Theory's spreading to the South in the Yuan Dynasty. In the meantime, Liu Hejian's descendants moved to Jiangxi province later as well as those studying the Theory personally also made similar contributions. His disciples, especially Jinshan Futu transmitted the Theory to Luo Zhiti, then to Zhu Danxi, all contributed to the southward diffusion too. The local medical officer who inherited the Theory expanded its influencing area. The inheritors' medical theory was not just limited to Hejian's Theory only, reflecting the academic progress at that time.

Classical affine W-algebras associated to Lie superalgebras

NASA Astrophysics Data System (ADS)

Suh, Uhi Rinn

2016-02-01

In this paper, we prove classical affine W-algebras associated to Lie superalgebras (W-superalgebras), which can be constructed in two different ways: via affine classical Hamiltonian reductions and via taking quasi-classical limits of quantum affine W-superalgebras. Also, we show that a classical finite W-superalgebra can be obtained by a Zhu algebra of a classical affine W-superalgebra. Using the definition by Hamiltonian reductions, we find free generators of a classical W-superalgebra associated to a minimal nilpotent. Moreover, we compute generators of the classical W-algebra associated to spo(2|3) and its principal nilpotent. In the last part of this paper, we introduce a generalization of classical affine W-superalgebras called classical affine fractional W-superalgebras. We show these have Poisson vertex algebra structures and find generators of a fractional W-superalgebra associated to a minimal nilpotent.

Performance and characterization of a new tannin-based coagulant

NASA Astrophysics Data System (ADS)

Beltrán-Heredia, J.; Sánchez-Martín, J.; Gómez-Muñoz, C.

2012-09-01

Diethanolamine and formaldehyde were employed to cationize tannins from black wattle. This novel coagulant called CDF was functionally characterized in removing sodium dodecylbenzene sulfonate (anionic surfactant) and Palatine Fast Black WAN (azoic dye). Refined tannin-derived commercial coagulants exhibited similar efficiency, while CDF presented higher coagulant ability than alum, a usual coagulant agent. Low doses of CDF (ca. 100 mg L-1) were able to remove more than 70 % of surfactant and more than 85 % of dye (initial pollutant concentration of ca. 100 mg L-1) and it presented no temperature affection and worked at a relatively wide pH range. Surfactant and dye removal responded to the classical coagulant-and-adsorption models, such as Frumkin-Fowler-Guggenheim or Gu and Zhu in the case of surfactant, and Langmuir and Freundlich in the case of dye.

Analysis and prediction of operating vehicle load effects on Highway bridges under the weight charge policy

NASA Astrophysics Data System (ADS)

Huang, Haiyun; Zhang, Junping; Li, Yonghe

2018-05-01

Under the weight charge policy, the weigh in motion data at a toll station on the Jing-Zhu Expressway were collected. The statistic analysis of vehicle load data was carried out. For calculating the operating vehicle load effects on bridges, by Monte Carlo method used to generate random traffic flow and influence line loading method, the maximum bending moment effect of simple supported beams were obtained. The extreme value I distribution and normal distribution were used to simulate the distribution of the maximum bending moment effect. By the extrapolation of Rice formula and the extreme value I distribution, the predicted values of the maximum load effects were obtained. By comparing with vehicle load effect according to current specification, some references were provided for the management of the operating vehicles and the revision of the bridge specifications.

[A preliminary discussion on the contents and value of All Diseases(1), the medical bamboo slips unearthed from Han tomb in Laoguanshan of Chengdu].

PubMed

Ye, Y; Zhang, Q; Ren, Y L; Li, J M

2017-05-28

Among the medical bamboo slips unearthed from Han tomb in Laoguanshan of Chengdu, the Zhu bing ( All Diseases ) is a monograph to discuss the characteristics of signs and symptoms. Based on the differences of writing styles, diseases involved, expounding methods and writing rules, the book is divided, by the research team, into 2 parts: All Diseases (1) and All Diseases (2). All Diseases (1) includes over 130 slips, 2 000 characters with totally more than 100 disease names, containing multiple clinical disciplines. The elaborated classification, varied naming methods, grasping the symptom characteristics guided by the four diagnostic approaches, paying attention to the comparison of similar diseases, and dealing with the prognosis and healthcare in this part reflect the holism of correspondence between human body and natural environment, and syndrome differentiation thought of combining disease with symptoms and signs, revealing its academic significance.

Removal of sodium lauryl sulphate by coagulation/flocculation with Moringa oleifera seed extract.

PubMed

Beltrán-Heredia, J; Sánchez-Martín, J

2009-05-30

Among other natural flocculant/coagulant agents, Moringa oleifera seed extract ability to remove an anionic surfactant has been evaluated and it has been found to be very interesting. Sodium lauryl sulphate was removed from aqueous solutions up to 80% through coagulation/flocculation process. pH and temperature were found to be not very important factors in removal efficiency. Freundlich (F), Frumkin-Fowler-Guggenheim (FFG) and Gu-Zhu (GZ) models were used to adjust experimental data in a solid-liquid adsorption hypothesis. Last one resulted to be the most accurate one. Several data fit parameters were determined, as Freundlich order, which was found to be 1.66, Flory-Huggins interaction parameter from FFG model, which was found to be 4.87; and limiting Moringa surfactant adsorption capacity from GZ model, which was found to be 2.13 x 10(-3)mol/g.

[S IV] in the NGC 5253 Supernebula: Ionized Gas Kinematics at High Resolution

NASA Astrophysics Data System (ADS)

Beck, Sara C.; Lacy, John H.; Turner, Jean L.; Kruger, Andrew; Richter, Matt; Crosthwaite, Lucian P.

2012-08-01

The nearby dwarf starburst galaxy NGC 5253 hosts a deeply embedded radio-infrared supernebula excited by thousands of O stars. We have observed this source in the 10.5 μm line of S +3 at 3.8 km s-1 spectral and 1farcs4 spatial resolution, using the high-resolution spectrometer TEXES on the IRTF. The line profile cannot be fit well by a single Gaussian. The best simple fit describes the gas with two Gaussians, one near the galactic velocity with FWHM 33.6 km s-1 and another of similar strength and FWHM 94 km s-1 centered ~20 km s-1 to the blue. This suggests a model for the supernebula in which gas flows toward us out of the molecular cloud, as in a "blister" or "champagne flow" or in the H II regions modelled by Zhu.

On the Security of a Two-Factor Authentication and Key Agreement Scheme for Telecare Medicine Information Systems.

PubMed

Arshad, Hamed; Teymoori, Vahid; Nikooghadam, Morteza; Abbassi, Hassan

2015-08-01

Telecare medicine information systems (TMISs) aim to deliver appropriate healthcare services in an efficient and secure manner to patients. A secure mechanism for authentication and key agreement is required to provide proper security in these systems. Recently, Bin Muhaya demonstrated some security weaknesses of Zhu's authentication and key agreement scheme and proposed a security enhanced authentication and key agreement scheme for TMISs. However, we show that Bin Muhaya's scheme is vulnerable to off-line password guessing attacks and does not provide perfect forward secrecy. Furthermore, in order to overcome the mentioned weaknesses, we propose a new two-factor anonymous authentication and key agreement scheme using the elliptic curve cryptosystem. Security and performance analyses demonstrate that the proposed scheme not only overcomes the weaknesses of Bin Muhaya's scheme, but also is about 2.73 times faster than Bin Muhaya's scheme.

The Characterization of Deqi during Moxibustion in Stroke Rats

PubMed Central

Lv, Zhimai; Liu, Zhongyong; Huang, Dandan; Chen, Rixin; Xie, Dingyi

2013-01-01

The efficacy of acupuncture and moxibustion is closely related to Deqi phenomenons, which are some subjective feelings. However, no one has reported the objective characterization of Deqi. Our preliminary research has found a phenomenon of tail temperature increasing (TTI) obviously in some stroke rats by suspended moxibustion at the acupoint dà zhuī (DU 14), which is similar to one characterization of Deqi during moxibustion that moxibustion heat is transferred from the original moxibustion acupoint to the other areas of the body. We wonder whether TTI is the objective indicator of Deqi characterization in animals. The present study showed that the stroke rat's recovery was also associated with TTI phenomenon. This suggests that TTI phenomenon is one objective characterization of the Deqi in stroke rats. Application of the TTI phenomenon contributes to explore the physiological mechanism of Deqi. PMID:24194777

The Characterization of Deqi during Moxibustion in Stroke Rats.

PubMed

Lv, Zhimai; Liu, Zhongyong; Huang, Dandan; Chen, Rixin; Xie, Dingyi

2013-01-01

The efficacy of acupuncture and moxibustion is closely related to Deqi phenomenons, which are some subjective feelings. However, no one has reported the objective characterization of Deqi. Our preliminary research has found a phenomenon of tail temperature increasing (TTI) obviously in some stroke rats by suspended moxibustion at the acupoint dà zhuī (DU 14), which is similar to one characterization of Deqi during moxibustion that moxibustion heat is transferred from the original moxibustion acupoint to the other areas of the body. We wonder whether TTI is the objective indicator of Deqi characterization in animals. The present study showed that the stroke rat's recovery was also associated with TTI phenomenon. This suggests that TTI phenomenon is one objective characterization of the Deqi in stroke rats. Application of the TTI phenomenon contributes to explore the physiological mechanism of Deqi.

The Effectiveness of Incorporating a Play-based Intervention to Improve Functional Mobility for a Child with Relapsed Acute Lymphoblastic Leukaemia: A Case Report.

PubMed

Vercher, Paula; Hung, You-Jou; Ko, Mansoo

2016-12-01

Acute lymphoblastic leukaemia (ALL) is one of the most common forms of cancer seen in children, accounting for one-fourth of all childhood cancers. These children typically present with decreased functional mobility, weakened lower extremity muscle strength and reduced exercise endurance and interests because of disease progressions and chemotherapy treatments. The purpose of this case report was to examine the effectiveness of incorporating a play-based physical therapy (PT) intervention programme to improve functional mobility for an inpatient with relapsed ALL undergoing chemotherapy. The patient was a 3-year-old male admitted to the hospital for relapsed ALL. He was diagnosed approximately 1 year earlier for which he had undergone chemotherapy and was later considered in remission at that time. When the patient relapsed, he underwent another round of chemotherapy and was waiting for a bone marrow transplant during his treatment during the course of this case report. For PT intervention, therapeutic exercises were incorporated into play to strengthen his lower extremity strength and muscle endurance. Functional activities were also incorporated into play to improve his aerobic capacity and overall quality of life. Multi-attribute health status classification system (HUI3) utility scores, 6-minute walk test distance (6MWT), lower extremity (LE) strength, transfer and tolerated treatment time were assessed to identify the effect of a PT intervention. Despite experiencing fatigue, the patient completed most of the treatments incorporated into play. After 5 weeks of PT intervention, the participant improved on HUI3 (pre: 0.72 and post: 0.92), 6MWT (pre: 156 ft and post: 489 ft), LE strength (squat), transfer (sit to stand) and tolerated treatment time (pre: 16 minutes and post: 44 minutes). This case report suggests that incorporating a play-based PT intervention programme could be physically tolerable and functionally beneficial for a young child with

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fu, Songbo; Wu, Jie; Li, Yuanyuan

To investigate the differences in urinary arsenic metabolism patterns of individuals exposed to a high concentration of inorganic arsenic (iAs) in drinking water, an epidemiological investigation was conducted with 155 individuals living in a village where the arsenic concentration in the drinking water was 969 μg/L. Blood and urine samples were collected from 66 individuals including 51 cases with skin lesions and 15 controls without skin lesions. The results showed that monomethylated arsenic (MMA), the percentage of MMA (%MMA) and the ratio of MMA to iAs (MMA/iAs) were significantly increased in patients with skin lesions as compared to controls, whilemore » dimethylated arsenic (DMA), the percentage of DMA (%DMA) and the ratio of DMA to MMA (DMA/MMA) were significantly reduced. The percent DMA of individuals with the Ala/Asp genotype of glutathione S-transferase omega 1 (GSTO1) was significantly lower than those with Ala/Ala. The percent MMA of individuals with the A2B/A2B genotype of arsenic (+ 3 oxidation state) methyltransferase (AS3MT) was significantly lower than those with AB/A2B. The iAs and total arsenic (tAs) content in the urine of a Tibetan population were significantly higher than that of Han and Hui ethnicities, whereas MMA/iAs was significantly lower than that of Han and Hui ethnicities. Our results showed that when exposed to the same arsenic environment, different individuals exhibited different urinary arsenic metabolism patterns. Gender and ethnicity affect these differences and above polymorphisms may be effectors too. - Highlights: • We first survey a village with high iAs content in the drinking water (969 μg/L). • 90 villagers suffered typical skin lesions with a morbidity rate of 58%. • Cases exhibited higher %MMA and MMA/iAs, and lower %DMA and DMA/MMA than controls. • Gender and ethnicity affect the differences of iAs methylation metabolism levels. • GSTO1 and AS3MT gene polymorphisms may be factors too.« less

A Shock-Adaptive Godunov Scheme Based on the Generalised Lagrangian Formulation

NASA Astrophysics Data System (ADS)

Lepage, C. Y.; Hui, W. H.

1995-12-01

Application of the Godunov scheme to the Euler equations of gas dynamics based on the Eulerian formulation of flow smears discontinuities, sliplines especially, over several computational cells, while the accuracy in the smooth flow region is of the order O( h), where h is the cell width. Based on the generalised Lagrangian formulation (GLF) of Hui et al., the Godunov scheme yields superior accuracy. By the use of coordinate streamlines in the GLF, the slipline—itself a streamline—is resolved crisply. Infinite shock resolution is achieved through the splitting of shock-cells. An improved entropy-conservation formulation of the governing equations is also proposed for computations in smooth flow regions. Finally, the use of the GLF substantially simplifies the programming logic resulting in a very robust, accurate, and efficient scheme.

Vertical velocity-CCN correlations

NASA Astrophysics Data System (ADS)

Hudson, J. G.; Noble, S. R.

2013-12-01

The realization that smaller cloud droplets evaporate more readily (Xue and Feingold 2006; Jiang et al. 2002) gives rise to an anti-indirect aerosol effect (IAE); less cloudiness with pollution. The greater latent heat exchange of the greater evaporation in more polluted clouds adds TKE and buoyancy gradients that can enhance vertical velocity (W), mixing and entrainment (Zhao and Austin 2005). Stronger W can increase horizontal motions, which can further enhance droplet evaporation, which further enhances latent heat exchange and vertical motions, thus, positive feedback. This could also include latent heat released during condensation (Lee and Feingold 2010), which is more rapid for the greater surface areas of the smaller more numerous droplets. These theories imply a positive relationship between within-cloud W variations; i.e., standard deviation of W (σw) and CCN concentration (NCCN) rather than W and NCCN. This implies greater turbulence in polluted clouds, which could possibly counteract the reduction of cloudiness of anti-IAE. During two stratus cloud projects, 50 cloud penetrations in 9 MASE flights and 34 cloud penetrations in 13 POST flights, within-cloud σw-NCCN showed correlation coefficients (R) of 0.50 and 0.39. Panel a shows similar within-cloud σw-NCCN R in all altitude bands for 17 RICO flights in small cumulus clouds. R for W-NCCN showed similar values but only at low altitudes. Out-of-cloud σw-NCCN showed similar high values except at the highest altitudes. Within-cloud σw showed higher R than within-cloud W with droplet concentrations (Nc), especially at higher altitudes. Panel b for 13 ICE-T cumulus cloud flights in the same location as RICO but during the opposite season, however, showed σw and W uncorrelated with NCCN at all altitudes; and W and σw correlated with Nc only at the highest altitudes. On the other hand, out-of-cloud σw was correlated with NCCN at all altitudes with R similar to the corresponding R of the other projects

Calcium Isotope Analysis with "Peak Cut" Method on Column Chemistry

NASA Astrophysics Data System (ADS)

Zhu, H.; Zhang, Z.; Liu, F.; Li, X.

2017-12-01

To eliminate isobaric interferences from elemental and molecular isobars (e.g., 40K+, 48Ti+, 88Sr2+, 24Mg16O+, 27Al16O+) on Ca isotopes during mass determination, samples should be purified through ion-exchange column chemistry before analysis. However, large Ca isotopic fractionation has been observed during column chemistry (Russell and Papanastassiou, 1978; Zhu et al., 2016). Therefore, full recovery during column chemistry is greatly needed, otherwise uncertainties would be caused by poor recovery (Zhu et al., 2016). Generally, matrix effects could be enhanced by full recovery, as other elements might overlap with Ca cut during column chemistry. Matrix effects and full recovery are difficult to balance and both need to be considered for high-precision analysis of stable Ca isotopes. Here, we investigate the influence of poor recovery on δ44/40Ca using TIMS with the double spike technique. The δ44/40Ca values of IAPSO seawater, ML3B-G and BHVO-2 in different Ca subcats (e.g., 0-20, 20-40, 40-60, 60-80, 80-100%) with 20% Ca recovery on column chemistry display limited variation after correction by the 42Ca-43Ca double spike technique with the exponential law. Notably, δ44/40Ca of each Ca subcut is quite consistent with δ44/40Ca of Ca cut with full recovery within error. Our results indicate that the 42Ca-43Ca double spike technique can simultaneously correct both of the Ca isotopic fractionation that occurred during column chemistry and thermal ionization mass spectrometry (TIMS) determination properly, because both of the isotopic fractionation occurred during analysis follow the exponential law well. Therefore, we propose the "peak cut" method on Ca column chemistry for samples with complex matrix effects. Briefly, for samples with low Ca contents, we can add the double spike before column chemistry, and only collect the middle of the Ca eluate and abandon the both sides of Ca eluate that might overlap with other elements (e.g., K, Sr). This method would

Preventing and controlling land subsidence in Shanghai -towards more integrated and effective land use and ground water governance in the Yangtze Delta

NASA Astrophysics Data System (ADS)

Dai, Liping

2016-04-01

The Yangtze Delta, covers 210,700 square kilometers and with 156 million inhabitants (NRDC, 2010; The National Bureau of Statistics, 2011), is one of the areas most severely affected by land subsidence in China. Up to 2012, the area with cumulative subsidence above 200 mm in Yangtze Delta has been closed to 10,000 square kilometers. Shanghai, located at the estuary of the Yangtze River and with a population of 23 million, is the most densely populated city in Yangtze Delta (The National Bureau of Statistics, 2011). Since 1921, the recorded cumulative subsidence has been 200 to 300 mm in the central area of the city (Chai, Shen, Zhu, & Zhang, 2005). Excessive pumping of groundwater is considered to be the leading reason, accounts for nearly 70%, of the city's land subsidence, the weight of skyscrapers and global warming also play hefty roles (30%) (Springer, 2012). Research has shown that the main method to control land subsidence in Shanghai is to prevent groundwater from dropping (Chai, Shen, Zhu, & Zhang, 2005), the city has made great efforts in this regard since 1965 (the beginning of the so-called "control period"), for example, it has been recharging underground water through 121 wells with more than 60,000 tons every day since 2012 (Chinadaily, 2012). It is a huge burden considering the city has been suffering from a shortage of fresh water. In 2013, with the other two provinces of Jiangsu and Zhejiang in Yangtze Delta, Shanghai signed a delta cooperation agreement on the prevention and control of land subsidence and jointly issued a Prevention and Control Planning on Land Subsidence in Yangtze Delta (2014-2020), which aims to establish a long-effect mechanism in the delta scope. This research aims to analyze and assess the land and groundwater governance arrangements related to land subsidence in the Yangtze Delta in general and Shanghai in specific, in order to develop optimizing adaptation strategies and associated governance arrangements. It examines the

Comparison of the New LEAF Area INDEX (LAI 3G) with the Kazahstan-Wide LEAF Area INDEX DATA SET (GGRS-LAI) over Central ASIA

NASA Astrophysics Data System (ADS)

Kappas, M.; Propastin, P.; Degener, J.; Renchin, T.

2014-12-01

Long-term global data sets of Leaf Area Index (LAI) are important for monitoring global vegetation dynamics. LAI indicating phenological development of vegetation is an important state variable for modeling land surface processes. The comparison of long-term data sets is based on two recently available data sets both derived from AVHRR time series. The LAI 3g data set introduced by Zaichun Zhu et al. (2013) is developed from the new improved third generation Global Inventory Modeling and Mapping Studies (GIMMS) Normalized Difference Vegetation Index (NDVI3g) and best-quality MODIS LAI data. The second long-term data set is based on the 8 km spatial resolution GIMMS-AVHRR data (GGRS-data set by Propastin et al. 2012). The GGRS-LAI product uses a three-dimensional physical radiative transfer model which establishes relationship between LAI, vegetation fractional cover and given patterns of surface reflectance, view-illumination conditions and optical properties of vegetation. The model incorporates a number of site/region specific parameters, including the vegetation architecture variables such as leaf angle distribution, clumping index, and light extinction coefficient. For the application of the model to Kazakhstan, the vegetation architecture variables were computed at the local (pixel) level based on extensive field surveys of the biophysical properties of vegetation in representative grassland areas of Kazakhstan. The comparison of both long-term data sets will be used to interpret their quality for scientific research in other disciplines. References:Propastin, P., Kappas, M. (2012). Retrieval of coarse-resolution leaf area index over the Republic of Kazakhstan using NOAA AVHRR satellite data and ground measurements," Remote Sensing, vol. 4, no. 1, pp. 220-246. Zaichun Zhu, Jian Bi, Yaozhong Pan, Sangram Ganguly, Alessandro Anav, Liang Xu, Arindam Samanta, Shilong Piao, Ramakrishna R. Nemani and Ranga B. Myneni (2013). Global Data Sets of Vegetation Leaf Area

Indonemoura annamensis-a new species of stonefly from Vietnam (Plecoptera: Nemouridae).

PubMed

Fochetti, Romolo; Ceci, Massimo

2016-06-07

The amphinemurine genus Indonemoura Baumann (1975) was proposed for species previously included in the genera Protonemura Kempny and Nemoura Latreille. Baumann (1975) designated P. indica Kimmins, 1947 (in Kimmins 1946) as the type species. He also transferred 14 additional species from Protonemura and Nemoura into this genus. The genus is distributed mainly in the Oriental region (only one species from Tibet, close to the eastern border of the Palaearctic Region) and many new species have been added in the last decades (Zwick & Sivec 1980; Shimizu 1994a & b; Zhu et al. 2002; Li et al. 2005; Li & Yang 2005, 2006; Wang et al. 2006; Sivec & Stark 2010) including presently 53 species (DeWalt et al. 2009). Sivec & Stark (2010) first described three Indonemoura species from Vietnam, I. angulata, I. clavata, and I. tricantha. These three species are the only Indonemoura presently known for Vietnam.

Stress Recovery and Error Estimation for Shell Structures

NASA Technical Reports Server (NTRS)

Yazdani, A. A.; Riggs, H. R.; Tessler, A.

2000-01-01

The Penalized Discrete Least-Squares (PDLS) stress recovery (smoothing) technique developed for two dimensional linear elliptic problems is adapted here to three-dimensional shell structures. The surfaces are restricted to those which have a 2-D parametric representation, or which can be built-up of such surfaces. The proposed strategy involves mapping the finite element results to the 2-D parametric space which describes the geometry, and smoothing is carried out in the parametric space using the PDLS-based Smoothing Element Analysis (SEA). Numerical results for two well-known shell problems are presented to illustrate the performance of SEA/PDLS for these problems. The recovered stresses are used in the Zienkiewicz-Zhu a posteriori error estimator. The estimated errors are used to demonstrate the performance of SEA-recovered stresses in automated adaptive mesh refinement of shell structures. The numerical results are encouraging. Further testing involving more complex, practical structures is necessary.

PAB3D Simulations of a Nozzle with Fluidic Injection for Yaw Thrust-Vector Control

NASA Technical Reports Server (NTRS)

Deere, Karen A.

1998-01-01

An experimental and computational study was conducted on an exhaust nozzle with fluidic injection for yaw thrust-vector control. The nozzle concept was tested experimentally in the NASA Langley Jet Exit Test Facility (JETF) at nozzle pressure ratios up to 4 and secondary fluidic injection flow rates up to 15 percent of the primary flow rate. Although many injection-port geometries and two nozzle planforms (symmetric and asymmetric) were tested experimentally, this paper focuses on the computational results of the more successful asymmetric planform with a slot injection port. This nozzle concept was simulated with the Navier-Stokes flow solver, PAB3D, invoking the Shih, Zhu, and Lumley algebraic Reynolds stress turbulence model (ASM) at nozzle pressure ratios (NPRs) of 2,3, and 4 with secondary to primary injection flow rates (w(sub s)/w(sub p)) of 0, 2, 7 and 10 percent.

Classical affine W-algebras associated to Lie superalgebras

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suh, Uhi Rinn, E-mail: uhrisu1@math.snu.ac.kr

2016-02-15

In this paper, we prove classical affine W-algebras associated to Lie superalgebras (W-superalgebras), which can be constructed in two different ways: via affine classical Hamiltonian reductions and via taking quasi-classical limits of quantum affine W-superalgebras. Also, we show that a classical finite W-superalgebra can be obtained by a Zhu algebra of a classical affine W-superalgebra. Using the definition by Hamiltonian reductions, we find free generators of a classical W-superalgebra associated to a minimal nilpotent. Moreover, we compute generators of the classical W-algebra associated to spo(2|3) and its principal nilpotent. In the last part of this paper, we introduce a generalizationmore » of classical affine W-superalgebras called classical affine fractional W-superalgebras. We show these have Poisson vertex algebra structures and find generators of a fractional W-superalgebra associated to a minimal nilpotent.« less

A faster 1.375-approximation algorithm for sorting by transpositions.

PubMed

Cunha, Luís Felipe I; Kowada, Luis Antonio B; Hausen, Rodrigo de A; de Figueiredo, Celina M H

2015-11-01

Sorting by Transpositions is an NP-hard problem for which several polynomial-time approximation algorithms have been developed. Hartman and Shamir (2006) developed a 1.5-approximation [Formula: see text] algorithm, whose running time was improved to O(nlogn) by Feng and Zhu (2007) with a data structure they defined, the permutation tree. Elias and Hartman (2006) developed a 1.375-approximation O(n(2)) algorithm, and Firoz et al. (2011) claimed an improvement to the running time, from O(n(2)) to O(nlogn), by using the permutation tree. We provide counter-examples to the correctness of Firoz et al.'s strategy, showing that it is not possible to reach a component by sufficient extensions using the method proposed by them. In addition, we propose a 1.375-approximation algorithm, modifying Elias and Hartman's approach with the use of permutation trees and achieving O(nlogn) time.

Neural representations of close others in collectivistic brains

PubMed Central

Wang, Gang; Mao, Lihua; Ma, Yina; Yang, Xuedong; Cao, Jingqian; Liu, Xi; Wang, Jinzhao; Wang, Xiaoying

2012-01-01

Our recent work showed that close relationships result in shared cognitive and neural representations of the self and one’s mother in collectivistic individuals (Zhu et al., 2007, Neuroimage, 34, 1310–7). However, it remains unknown whether close others, such as mother, father and best friend, are differentially represented in collectivistic brains. Here, using functional magnetic resonance imaging and a trait judgment task, we showed evidence that, while trait judgments of the self and mother generated comparable activity in the medial prefrontal cortex (MPFC) and anterior cingulate (ACC) of Chinese adults, trait judgments of mother induced greater MPFC/ACC activity than trait judgments of father and best friend. Our results suggest that, while neural representations of the self and mother overlapped in the MPFC/ACC, close others such as mother, father and best friend are unequally represented in the MPFC/ACC of collectivistic brains. PMID:21382966

Thermodynamic properties for arsenic minerals and aqueous species

USGS Publications Warehouse

Nordstrom, D. Kirk; Majzlan, Juraj; Königsberger, Erich; Bowell, Robert J.; Alpers, Charles N.; Jamieson, Heather E.; Nordstrom, D. Kirk; Majzlan, Juraj

2014-01-01

Quantitative geochemical calculations are not possible without thermodynamic databases and considerable advances in the quantity and quality of these databases have been made since the early days of Lewis and Randall (1923), Latimer (1952), and Rossini et al. (1952). Oelkers et al. (2009) wrote, “The creation of thermodynamic databases may be one of the greatest advances in the field of geochemistry of the last century.” Thermodynamic data have been used for basic research needs and for a countless variety of applications in hazardous waste management and policy making (Zhu and Anderson 2002; Nordstrom and Archer 2003; Bethke 2008; Oelkers and Schott 2009). The challenge today is to evaluate thermodynamic data for internal consistency, to reach a better consensus of the most reliable properties, to determine the degree of certainty needed for geochemical modeling, and to agree on priorities for further measurements and evaluations.

Phylogenic analysis and forensic genetic characterization of Chinese Uyghur group via autosomal multi STR markers

PubMed Central

Jin, Xiaoye; Wei, Yuanyuan; Chen, Jiangang; Kong, Tingting; Mu, Yuling; Guo, Yuxin; Dong, Qian; Xie, Tong; Meng, Haotian; Zhang, Meng; Li, Jianfei; Li, Xiaopeng; Zhu, Bofeng

2017-01-01

We investigated the allelic frequencies and forensic descriptive parameters of 23 autosomal short tandem repeat loci in a randomly selected sample of 1218 unrelated healthy Uyghur individuals residing in the Xinjiang Uyghur Autonomous Region, northwest China. A total of 281 alleles at these loci were identified and their corresponding allelic frequencies ranged from 0.0004 to 0.5390. The combined match probability and combined probability of exclusion of all loci were 5.192 × 10−29 and 0.9999999996594, respectively. The results of population genetic study manifested that Uyghur had close relationships with those contiguous populations, such as Xibe and Hui groups. In a word, these autosomal short tandem repeat loci were highly informative in Uyghur group and the multiplex PCR system could be used as a valuable tool for forensic caseworks and population genetic analysis. PMID:29088750

Phylogenic analysis and forensic genetic characterization of Chinese Uyghur group via autosomal multi STR markers.

PubMed

Jin, Xiaoye; Wei, Yuanyuan; Chen, Jiangang; Kong, Tingting; Mu, Yuling; Guo, Yuxin; Dong, Qian; Xie, Tong; Meng, Haotian; Zhang, Meng; Li, Jianfei; Li, Xiaopeng; Zhu, Bofeng

2017-09-26

We investigated the allelic frequencies and forensic descriptive parameters of 23 autosomal short tandem repeat loci in a randomly selected sample of 1218 unrelated healthy Uyghur individuals residing in the Xinjiang Uyghur Autonomous Region, northwest China. A total of 281 alleles at these loci were identified and their corresponding allelic frequencies ranged from 0.0004 to 0.5390. The combined match probability and combined probability of exclusion of all loci were 5.192 × 10 -29 and 0.9999999996594, respectively. The results of population genetic study manifested that Uyghur had close relationships with those contiguous populations, such as Xibe and Hui groups. In a word, these autosomal short tandem repeat loci were highly informative in Uyghur group and the multiplex PCR system could be used as a valuable tool for forensic caseworks and population genetic analysis.

Search for the Higgs Boson and for Anomalous Quartic Gauge Boson Couplings in the WW Channel with Dielectron Events with the D0 Experiment at the Tevatron; Recherche du boson de Higgs et de couplages de jauge quartiques anormaux dans le canal WW en électrons dans l'expérience D0 au Tevatron (in French)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chapon, Emilien

Le paysage de la physique des particules a subi des changements majeurs entre le début de cette thèse, en septembre 2010, et sa n en juin 2013. On peut notamment qualier l'année 2012 de date-clé dans l'histoire de la physique des particules. En 2012, une nouvelle particule a été découverte au LHC [1, 2], dont la majeure partie de la communauté s'accorde aujourd'hui à dire qu'il s'agit très probablement du boson de Higgs. Cet événement est intervenu peu après une sorte de passage de relais entre le Tevatron, arrêté le 30 septembre 2011, et le LHC, dont les toutes premièresmore » collisions sont intervenues le 23 novembre 2009.« less

Science and management in the Hanalei watershed: a trans-disciplinary approach

USGS Publications Warehouse

Field, Michael E.; Berg, Carl J.; Cochran, Susan A.

2007-01-01

The results of recent studies in the Hanalei watershed are impressive, both in content and breadth. Funded, directed, and/or conducted by investigators from many disciplines from local organizations (the Hanalei Watershed Hui), the University of Hawai‘i, the State of Hawai‘i (Department of Health, Department of Land and Natural Resources), and Federal organizations (U.S. Department of Agriculture, U.S. Geological Survey, Environmental Protection Agency, National Oceanic and Atmospheric Agency), their sum total have contributed markedly to our understanding of processes in the watershed. There has been an overwhelming amount of information that has been collected in the Hanalei Bay Watershed from Mt. Waialeale to the far reefs in just the past 5 years. This workshop was initiated to document our collective understanding, better integrate our results, and identify the salient issues that remain to be studied.

Electronic structure of the ingredient planes of Bi2Sr2CaCu2O8 + δ and Bi2Sr2CuO6 + δ superconductors

NASA Astrophysics Data System (ADS)

Ma, Xucun

Understanding the mechanism of high transition temperature superconductivity in cuprates has been hindered by the apparent complexity of their multilayered crystal structure. Using a cryogenic scanning tunneling microscopy (STM), we report on layer-by-layer probing of the electronic structures of the ingredient planes (BiO, SrO, CuO2) of Bi2Sr2CaCu2O8 + δ (Bi-2212) and Bi2Sr2CuO6 + δ (Bi-2201) superconductors prepared by argon-ion bombardment and annealing (IBA) technique. We show that the well-known pseudogap (PG) feature observed by STM is inherently a property of the charge reservoir planes and thus irrelevant directly to Cooper pairing. The CuO2 planes are exclusively characterized by a small gap inside the PG. The small gap becomes invisible near Tc, which we identify as the superconducting gap. The results constitute severe constraints on any microscopic model for high Tc superconductivity in cuprates. Contributors: Yan-Feng Lv, Wen-Lin Wang, Hao Ding, Yang Wang, Yong Zhong, Ying Ding, Ruidan Zhong, John Schneeloch, Gen-Da Gu, Lili Wang, Ke He, Shuai-Hua Ji, Lin Zhao, Xing-Jiang Zhou Can-Li Song, and Qi-Kun Xue. NSF and MOST of China.

Corticosteroid receptors adopt distinct cyclical transcriptional signatures.

PubMed

Le Billan, Florian; Amazit, Larbi; Bleakley, Kevin; Xue, Qiong-Yao; Pussard, Eric; Lhadj, Christophe; Kolkhof, Peter; Viengchareun, Say; Fagart, Jérôme; Lombès, Marc

2018-05-07

Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate major pathophysiologic functions. High homology between these receptors accounts for the crossbinding of their corresponding ligands, MR being activated by both aldosterone and cortisol and GR essentially activated by cortisol. Their coexpression and ability to bind similar DNA motifs highlight the need to investigate their respective contributions to overall corticosteroid signaling. Here, we decipher the transcriptional regulatory mechanisms that underlie selective effects of MRs and GRs on shared genomic targets in a human renal cellular model. Kinetic, serial, and sequential chromatin immunoprecipitation approaches were performed on the period circadian protein 1 ( PER1) target gene, providing evidence that both receptors dynamically and cyclically interact at the same target promoter in a specific and distinct transcriptional signature. During this process, both receptors regulate PER1 gene by binding as homo- or heterodimers to the same promoter region. Our results suggest a novel level of MR-GR target gene regulation, which should be considered for a better and integrated understanding of corticosteroid-related pathophysiology.-Le Billan, F., Amazit, L., Bleakley, K., Xue, Q.-Y., Pussard, E., Lhadj, C., Kolkhof, P., Viengchareun, S., Fagart, J., Lombès, M. Corticosteroid receptors adopt distinct cyclical transcriptional signatures.

Fluid flow and heat transfer of carbon nanotubes along a flat plate with Navier slip boundary

NASA Astrophysics Data System (ADS)

Khan, W. A.; Khan, Z. H.; Rahi, M.

2014-06-01

Homogeneous flow model is used to study the flow and heat transfer of carbon nanotubes (CNTs) along a flat plate subjected to Navier slip and uniform heat flux boundary conditions. This is the first paper on the flow and heat transfer of CNTs along a flat plate. Two types of CNTs, namely, single- and multi-wall CNTs are used with water, kerosene or engine oil as base fluids. The empirical correlations are used for the thermophysical properties of CNTs in terms of the solid volume fraction of CNTs. For the effective thermal conductivity of CNTs, Xue (Phys B Condens Matter 368:302-307, 2005) model has been used and the results are compared with the existing theoretical models. The governing partial differential equations and boundary conditions are converted into a set of nonlinear ordinary differential equations using suitable similarity transformations. These equations are solved numerically using a very efficient finite difference method with shooting scheme. The effects of the governing parameters on the dimensionless velocity, temperature, skin friction, and Nusselt numbers are investigated and presented in graphical and tabular forms. The numerical results of skin friction and Nusselt numbers are compared with the available data for special cases and are found in good agreement.