Environmental assessment for the Plating Shop Replacement, Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-03-01

The existing of Y-12 Plant Plating Shop provides vital support functions for the US Department of Energy (DOE) Defense Programs operations. In addition to weapon component plating, the facility performs other plating services to support existing operations for the Y-12 Plant, other DOE facilities, and other federal agencies. In addition, the facility would also provide essential deplating services for weapons reclamation and teardown. The existing Y-12 Plant Plating Shop is presently located in a structure which is rapidly deteriorating and obsolete. The existing building structure was originally designed to house a steam plant, not chemical plating operations. As such, vaporsmore » from plating operations have deteriorated the structure to a point where a new facility is needed for continued safe operations. The potential environmental impacts of the proposed action was anticipated to be minimal and would affect no environmentally sensitive areas. Some short-term construction- and demolition-related effects would occur in an already highly industrialized setting. These include temporarily disturbing 72,000 square feet of land for the new plating shop and related site preparation activities, constructing a permanent building on part of the area, and using 80 construction personnel over a period of 18 months for site preparation and construction. Demolition effects vary depending on the environmentally suitable option selected, but they could involve as much as 262 cubic yards of concrete rubble and approximately 1600 cubic yards of soil disposed as waste. Either 1600 cubic yards of fresh soil or 1850 yards of clay and fresh soil could be required. Soil erosion would be minimal. Approximately 20 construction personnel would be involved for 12 months in demolition activities.« less

44 CFR 295.12 - Election of remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Election of remedies. 295.12 Section 295.12 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... CGFAA § 295.12 Election of remedies. (a) By filing a Notice of Loss, an Injured Person waives the right...

44 CFR 295.12 - Election of remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Election of remedies. 295.12 Section 295.12 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... CGFAA § 295.12 Election of remedies. (a) By filing a Notice of Loss, an Injured Person waives the right...

12 CFR 3.14 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Remedies. 3.14 Section 3.14 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MINIMUM CAPITAL RATIOS; ISSUANCE OF DIRECTIVES Enforcement § 3.14 Remedies. A bank that does not have or maintain the minimum capital ratios applicable to it...

12 CFR 3.14 - Remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Remedies. 3.14 Section 3.14 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MINIMUM CAPITAL RATIOS; ISSUANCE OF DIRECTIVES Enforcement § 3.14 Remedies. A bank that does not have or maintain the minimum capital ratios applicable to it...

Report on the remedial investigation of Bear Creek Valley at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Volume 3: Appendix D -- Nature and extent of contamination report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-09-01

This Remedial Investigation (RI) Report characterizes the nature and extent of contamination, evaluates the fate and transport of contaminants, and assesses risk to human health and the environment resulting from waste disposal and other US Department of Energy (DOE) operations in Bear Creek Valley (BCV). BCV, which is located within the DOE Oak Ridge Reservation (ORR) encompasses multiple waste units containing hazardous and radioactive wastes arising from operations at the adjacent Oak Ridge Y-12 Plant. The primary waste units discussed in this RI Report are the S-3 Site, Oil Landfarm (OLF), Boneyard/Burnyard (BYBY), Sanitary Landfill 1 (SL 1), and Bearmore » Creek Burial Grounds (BCBG). These waste units, plus the contaminated media resulting from environmental transport of the wastes from these units, are the subject of this RI. This BCV RI Report represents the first major step in the decision-making process for the BCV watershed. The RI results, in concert with the follow-on FS will form the basis for the Proposed Plan and Record of Decision for all BCV sites. This comprehensive decision document process will meet the objectives of the watershed approach for BCV. Appendix D describes the nature and extent of contamination in environmental media and wastes.« less

Y-12 Plant decontamination and decommissioning technology logic diagram for Building 9201-4. Volume 2: Technology logic diagram

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-09-01

The Y-12 Plant Decontamination and Decommissioning Technology Logic Diagram for Building 9201-4 (TLD) was developed to provide a decision-support tool that relates decontamination and decommissioning (D and D) problems at Bldg. 9201-4 to potential technologies that can remediate these problems. This TLD identifies the research, development, demonstration, testing, and evaluation needed for sufficient development of these technologies to allow for technology transfer and application to D and D and waste management (WM) activities. It is essential that follow-on engineering studies be conducted to build on the output of this project. These studies will begin by selecting the most promising technologiesmore » identified in the TLD and by finding an optimum mix of technologies that will provide a socially acceptable balance between cost and risk. The TLD consists of three fundamentally separate volumes: Vol. 1 (Technology Evaluation), Vol. 2 (Technology Logic Diagram), and Vol. 3 (Technology Evaluation Data Sheets). Volume 2 contains the logic linkages among environmental management goals, environmental problems, and the various technologies that have the potential to solve these problems. Volume 2 has been divided into five sections: Characterization, Decontamination, Dismantlement, Robotics/Automation, and Waste Management. Each section contains logical breakdowns of the Y-12 D and D problems by subject area and identifies technologies that can be reasonably applied to each D and D challenge.« less

Evaluation of Calendar Year 1997 Groundwater and Surface Water Quality Data For The Upper East Fork Poplar Creek Hydrogeologic Regime At The U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, S.B.

1998-09-01

1 1.0 INTRODUCTION This report presents an evaluation of the groundwater quality monitoring data reported in: Calendar Year 1997 Annual Groundwatw Monitoring Report for the Upper East Fork Poplar Creek Hydrogeologtc Rep-meat the US. Department of Energy Y-12 Plant, Oak Ridge, Tennessee (AJA Technical Services, Inc. 1998), which is hereafter referenced as the Annual Monitoring Report. Section 2.0 presents background information for the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime) that is relevant to data evaluation, including brief descriptions of the geology, the groundwater flow system, the contaminant source areas, and the extent of groundwater contamination inmore » the regime. Section 3.0 provides an overview of the groundwater sampling and analysis activities petiormed during calendar year (CY) 1997, including monitoring well locations, sampling frequency and methods, and laboratory analyses. Evaluation and interpretation of the monitoring da% described in Section 4.0, is generally focused on an overview of data quality assurance/quality control (QA/QC), long-term concentration trends for selected inorganic, organic, and radiological contaminants, and consistency with applicable site-specific conceptual contaminant transport models described in: Report on the Remedial Investigation of the Upper East Fork Poplar Creek Characterization Area at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee (U.S. Department of Energy 1998), which is referenced hereafter as the Remedial Investigation @I) Report. Findings of the data evaluations are summarized :in Section 5.0 and a list of technical reports and regulatory documents cited for more detailed irdormation (Section 6.0) concludes the report. All of the illustrations (maps and trend graphs) and data summary tables referenced in the text are presented in Appendm A and Appendix B, respectively. Appendix C provides a summary of the analytical results that meet applicable data quality objectives

Ability of salt marsh plants for TBT remediation in sediments.

PubMed

Carvalho, Pedro N; Basto, M Clara P; Silva, Manuela F G M; Machado, Ana; Bordalo, A A; Vasconcelos, M Teresa S D

2010-07-01

The capability of Halimione portulacoides, Spartina maritima, and Sarcocornia fruticosa (halophytes very commonly found in salt marshes from Mediterranean areas) for enhancing remediation of tributyltin (TBT) from estuarine sediments was investigated, using different experimental conditions. The influence of H. portulacoides on degradation of the butyltin compounds was assessed in two different ways: (1) a 9-month ex situ study carried out in a site of Sado River estuary, center of Portugal, which used polluted sediments collected at other nonvegetated site from the same estuary; and (2) a 12-month laboratorial study, using both plant and sediment collected at a relatively clean site of Cávado River estuary, north of Portugal, the sediment being doped with TBT, DBT, and MBT at the beginning of the experiment. The role of both S. fruticosa and S. maritima on TBT remediation in sediments was evaluated in situ, in salt marshes from Marim channel of Ria Formosa lagoon, south of Portugal, which has large areas colonized by each one of these two plants. For estimation of microbial abundance, total cell counts of sediment samples were enumerated by the DAPI direct count method. Butyltin analyses in sediment were performed using a method previously validated, which consisted of headspace solid-phase micro-extraction combined with gas chromatography-mass spectrometry after in situ ethylation (with tetraethylborate). Sediments colonized both ex situ and at lab by H. portulacoides displayed TBT levels about 30% lower than those for nonvegetated sediments with identical initial composition, after 9-12 months of plant exposure. In addition, H. portulacoides showed to be able of stimulating bacterial growth in the plant rhizosphere, which probably included degraders of TBT. In the in situ study, which compared the levels of TBT, DBT, and MBT in nonvegetated sediment and in sediments colonized by either S. maritima or S. fruticosa from the same area, TBT and DBT were only

History of mercury use and environmental contamination at the Oak Ridge Y-12 Plant.

PubMed

Brooks, Scott C; Southworth, George R

2011-01-01

Between 1950 and 1963 approximately 11 million kilograms of mercury (Hg) were used at the Oak Ridge Y-12 National Security Complex (Y-12 NSC) for lithium isotope separation processes. About 3% of the Hg was lost to the air, soil and rock under facilities, and East Fork Poplar Creek (EFPC) which originates in the plant site. Smaller amounts of Hg were used at other Oak Ridge facilities with similar results. Although the primary Hg discharges from Y-12 NSC stopped in 1963, small amounts of Hg continue to be released into the creek from point sources and diffuse contaminated soil and groundwater sources within Y-12 NSC. Mercury concentration in EFPC has decreased 85% from ∼2000 ng/L in the 1980s. In general, methylmercury concentrations in water and in fish have not declined in response to improvements in water quality and exhibit trends of increasing concentration in some cases. Published by Elsevier Ltd.

25 CFR 67.12 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Exhaustion of administrative remedies. 67.12 Section 67.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR TRIBAL GOVERNMENT PREPARATION OF A ROLL OF INDEPENDENT SEMINOLE INDIANS OF FLORIDA § 67.12 Exhaustion of administrative remedies. The...

12 CFR 1780.56 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Exhaustion of administrative remedies. 1780.56... Posthearing Proceedings § 1780.56 Exhaustion of administrative remedies. To exhaust administrative remedies as... file exceptions with the Director under § 1780.54. A party must exhaust administrative remedies as a...

12 CFR 1780.56 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Exhaustion of administrative remedies. 1780.56... Posthearing Proceedings § 1780.56 Exhaustion of administrative remedies. To exhaust administrative remedies as... file exceptions with the Director under § 1780.54. A party must exhaust administrative remedies as a...

12 CFR 908.66 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Exhaustion of administrative remedies. 908.66... Proceedings § 908.66 Exhaustion of administrative remedies. To exhaust administrative remedies as to any issue... with the Board of Directors under § 908.64. A party must exhaust administrative remedies as a...

12 CFR 908.66 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Exhaustion of administrative remedies. 908.66... Proceedings § 908.66 Exhaustion of administrative remedies. To exhaust administrative remedies as to any issue... with the Board of Directors under § 908.64. A party must exhaust administrative remedies as a...

Site characterization summary report for dry weather surface water sampling upper East Fork Poplar Creek characterization area Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This report describes activities associated with conducting dry weather surface water sampling of Upper East Fork Poplar Creek (UEFPC) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. This activity is a portion of the work to be performed at UEFPC Operable Unit (OU) 1 [now known as the UEFPC Characterization Area (CA)], as described in the RCRA Facility Investigation Plan for Group 4 at the Oak- Ridge Y-12 Plant, Oak Ridge, Tennessee and in the Response to Comments and Recommendations on RCRA Facility Investigation Plan for Group 4 at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee, Volume 1,more » Operable Unit 1. Because these documents contained sensitive information, they were labeled as unclassified controlled nuclear information and as such are not readily available for public review. To address this issue the U.S. Department of Energy (DOE) published an unclassified, nonsensitive version of the initial plan, text and appendixes, of this Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) Plan in early 1994. These documents describe a program for collecting four rounds of wet weather and dry weather surface water samples and one round of sediment samples from UEFPC. They provide the strategy for the overall sample collection program including dry weather sampling, wet weather sampling, and sediment sampling. Figure 1.1 is a schematic flowchart of the overall sampling strategy and other associated activities. A Quality Assurance Project Plan (QAPJP) was prepared to specifically address four rounds of dry weather surface water sampling and one round of sediment sampling. For a variety of reasons, sediment sampling has not been conducted and has been deferred to the UEFPC CA Remedial Investigation (RI), as has wet weather sampling.« less

Postconstruction report of the United Nuclear Corporation Disposal Site at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Environmental Restoration Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oakley, L.B.; Siberell, J.K.; Voskuil, T.L.

1993-06-01

Remedial actions conducted under the auspices of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) were completed at the Y-12 United Nuclear Corporation (UNC) Disposal Site in August 1992. The purpose of this Postconstruction Report is to summarize numerous technical reports and provide CERCLA documentation for completion of the remedial actions. Other CERCLA reports, such as the Feasibility Study for the UNC Disposal Site, provide documentation leading up to the remedial action decision. The remedial action chosen, placement of a modified RCRA cap, was completed successfully, and performance standards were either met or exceeded. This remedial action provided solutionsmore » to two environmentally contaminated areas and achieved the goal of minimizing the potential for contamination of the shallow groundwater downgradient of the site, thereby providing protection of human health and the environment. Surveillance and maintenance of the cap will be accomplished to ensure cap integrity, and groundwater monitoring downgradient of the site will continue to confirm the acceptability of the remedial action chosen.« less

Flood analyses for Department of Energy Y-12, ORNL and K-25 Plants. Flood analyses in support of flood emergency planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-05-01

The study involved defining the flood potential and local rainfall depth and duration data for the Department of Energy`s (DOE) Y-12, Oak Ridge National Laboratory (ORNL), and K-25 plants. All three plants are subject to flooding from the Clinch River. In addition, the Y-12 plant is subject to flooding from East Fork Poplar and Bear Creeks, the ORNL plant from Whiteoak Creek and Melton Branch, and the K-25 plant from Poplar Creek. Determination of flood levels included consideration of both rainfall events and postulated failures of Norris and Melton Hill Dams in seismic events.

7 CFR 3022.12 - Remedies for noncompliance.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., DEPARTMENT OF AGRICULTURE RESEARCH INSTITUTIONS CONDUCTING USDA-FUNDED EXTRAMURAL RESEARCH; RESEARCH MISCONDUCT § 3022.12 Remedies for noncompliance. USDA agencies' implementation procedures identify the...

7 CFR 3022.12 - Remedies for noncompliance.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., DEPARTMENT OF AGRICULTURE RESEARCH INSTITUTIONS CONDUCTING USDA-FUNDED EXTRAMURAL RESEARCH; RESEARCH MISCONDUCT § 3022.12 Remedies for noncompliance. USDA agencies' implementation procedures identify the...

7 CFR 3022.12 - Remedies for noncompliance.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., DEPARTMENT OF AGRICULTURE RESEARCH INSTITUTIONS CONDUCTING USDA-FUNDED EXTRAMURAL RESEARCH; RESEARCH MISCONDUCT § 3022.12 Remedies for noncompliance. USDA agencies' implementation procedures identify the...

7 CFR 3022.12 - Remedies for noncompliance.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., DEPARTMENT OF AGRICULTURE RESEARCH INSTITUTIONS CONDUCTING USDA-FUNDED EXTRAMURAL RESEARCH; RESEARCH MISCONDUCT § 3022.12 Remedies for noncompliance. USDA agencies' implementation procedures identify the...

Second report on the Oak Ridge Y-12 Plant Biological Monitoring and Abatement Program for East Fork Poplar Creek

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hinzman, R.L.; Adams, S.M.; Black, M.C.

1993-06-01

As stipulated in the National Pollutant Discharge Elimination System (NDPES) permit issued to the Oak Ridge Y-12 Plant on May 24, 1986, a Biological Monitoring and Abatement Program (BMAP) was developed for the receiving stream, East Fork Poplar Creek (EFPC). The objectives of BMAP are (1) to demonstrate that the current effluent limitations established for the Y-12 Plant protect the classified uses of EFPC (e.g., the growth and propagation of fish and aquatic life), as designated by the Tennessee Department of Environment and Conservation (TDEC) and (2) to document the ecological effects resulting from implementation of a Water Pollution Controlmore » Program that includes construction of several large wastewater treatment facilities. BMAP consists of four major tasks: (1) ambient toxicity testing; (2) bioaccumulation studies; (3) biological indicator studies; and (4) ecological surveys of stream communities, including periphyton (attached algae), benthic (bottom-dwelling) macroinvertebrates, and fish. This document, the second in a series of reports on the results of the Y-12 Plant BMAP, describes studies that were conducted between July 1986 and July 1988, although additional data collected outside this time period are included, as appropriate.« less

First report on the Oak Ridge Y-12 Plant Biological Monitoring and Abatement Program for East Fork Poplar Creek

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loar, J.M.; Adams, S.M.; Allison, L.J.

1992-07-01

As stipulated in the National Pollutant Discharge Elimination System (NPDES) permit issued to the Oak Ridge Y-12 Plant on May 24, 1985, a Biological Monitoring and Abatement Program (BMAP) was developed for the receiving stream, East Fork Poplar Creek (EFPC). The objectives of the BMAP are (1) to demonstrate that the current effluent limitations established for the Oak Ridge Y-12 Plant protect the uses of EFPC (e.g., the growth and propagation of fish and aquatic life), as designated by the Tennessee Department of Environment and Conservation (TDEC) [formerly the Tennessee Department of Health and Environment (TDHE)], and (2) to documentmore » the ecological effects resulting from implementation of a water pollution control program that includes construction of several large wastewater treatment facilities. The BMAP consists of four major tasks: (1) ambient toxicity testing, (2) bioaccumulation studies, (3) biological indicator studies, and (4) ecological surveys of stream communities, including periphyton (attached algae), benthic macroinvertebrates, and fish. This document, the first in a series of reports on the results of the Y-12 Plant BMAP, describes studies that were conducted from May 1985 through September 1986.« less

Plant-bacteria partnerships for the remediation of persistent organic pollutants.

PubMed

Arslan, Muhammad; Imran, Asma; Khan, Qaiser Mahmood; Afzal, Muhammad

2017-02-01

High toxicity, bioaccumulation factor and widespread dispersal of persistent organic pollutants (POPs) cause environmental and human health hazards. The combined use of plants and bacteria is a promising approach for the remediation of soil and water contaminated with POPs. Plants provide residency and nutrients to their associated rhizosphere and endophytic bacteria. In return, the bacteria support plant growth by the degradation and detoxification of POPs. Moreover, they improve plant growth and health due to their innate plant growth-promoting mechanisms. This review provides a critical view of factors that affect absorption and translocation of POPs in plants and the limitations that plant have to deal with during the remediation of POPs. Moreover, the synergistic effects of plant-bacteria interactions in the phytoremediation of organic pollutants with special reference to POPs are discussed.

Y-12 Groundwater Protection Program Groundwater Monitoring Data Compendium, Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This document is a compendium of water quality and hydrologic characterization data obtained through December 2005 from the network of groundwater monitoring wells and surface water sampling stations (including springs and building sumps) at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) in Oak Ridge, Tennessee that have been sampled since January 2003. The primary objectives of this document, hereafter referenced as the Y-12 Groundwater Protection Program (GWPP) Compendium, are to: (1) Serve as a single-source reference for monitoring data that meet the requirements of the Y-12 GWPP, as defined in the Y-12 GWPP Management Plan (BWXTmore » Y-12 L.L.C. [BWXT] 2004); (2) Maintain a detailed analysis and evaluation of the monitoring data for each applicable well, spring, and surface water sampling station, with a focus on results for the primary inorganic, organic, and radiological contaminants in groundwater and surface water at Y-12; and (3) Ensure retention of ''institutional knowledge'' obtained over the long-term (>20-year) history of groundwater and surface water monitoring at Y-12 and the related sources of groundwater and surface water contamination. To achieve these goals, the Y-12 GWPP Compendium brings together salient hydrologic, geologic, geochemical, water-quality, and environmental compliance information that is otherwise disseminated throughout numerous technical documents and reports prepared in support of completed and ongoing environmental contamination assessment, remediation, and monitoring activities performed at Y-12. The following subsections provide background information regarding the overall scope and format of the Y-12 GWPP Compendium and the planned approach for distribution and revision (i.e., administration) of this ''living'' document.« less

49 CFR 510.12 - Remedies for failure to comply with compulsory process.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 6 2010-10-01 2010-10-01 false Remedies for failure to comply with compulsory process. 510.12 Section 510.12 Transportation Other Regulations Relating to Transportation (Continued... § 510.12 Remedies for failure to comply with compulsory process. Any failure to comply with compulsory...

Results of calendar year 1994 monitor well inspection and maintenance program, Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

McMaster, B.W.; Jones, S.B.; Sitzler, J.L.

1995-06-01

This document is a compendium of results of the calendar year 1994 Monitor Well Inspection and Maintenance Program at the Department of Energy Y-12 Plant in Oak Ridge, Tennessee. This report documents the work relating to well inspections and maintenance requests. Inspections are implemented in order to better assess the condition and maintenance needs of wells that are actively being monitored. Currently this approach calls for inspecting all wells on a routine (annual or triennial) basis which are: (1) in an active sampling program; (2) included in a hydrologic study; or (3) not in service, but not scheduled for pluggingmore » and abandonment. Routine inspections help to ensure that representative groundwater samples and hydrologic data are being collected, and contribute to the life expectancy of each well. This report formally presents well inspection and maintenance activities that were conducted at the Y-12 Plant during 1994. All inspections were conducted between April and December.« less

Calendar year 1993 groundwater quality report for the Chestnut Ridge Hydrogeologic Regime, Y-12 Plant, Oak Ridge, Tennessee. 1993 groundwater quality data and calculated rate of contaminant migration, Part 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-02-01

This annual groundwater report contains groundwater quality data obtained during the 1993 calendar year (CY) at several hazardous and non-hazardous waste-management facilities associated with the US Department of Energy (DOE) Y-12 Plant located on the DOE Oak Ridge Reservation (ORR) southeast of Oak Ridge, Tennessee. These sites are located south of the Y-12 Plant in the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime), which is one of three regimes defined for the purposes of groundwater quality monitoring at the Y-12 Plant. The Environmental Management Department of the Y-12 Plant Health, Safety, Environment, and Accountability Organization manages the groundwater monitoring activitiesmore » in each regime as part of the Y-12 Plant Groundwater Protection Program (GWPP). The annual groundwater report for the Chestnut Ridge Regime is completed in two-parts; Part 1 (this report) containing the groundwater quality data and Part 2 containing a detailed evaluation of the data. The primary purpose of this report is to serve as a reference for the groundwater quality data obtained each year under the lead of the Y-12 Plant GWPP. However, because it contains information needed to comply with Resource Conservation and Recovery Act (RCRA) interim status assessment monitoring and reporting requirements, this report is submitted to the Tennessee Department of Health and Environment (TDEC) by the RCRA reporting deadline.« less

Medicinal plants used as home remedies: a family survey by first year medical students.

PubMed

Sewani-Rusike, Constance R; Mammen, Marykutty

2014-01-01

There is a hierarchical organisation of knowledge in the use of medicinal plants in communities. Medicinal use knowledge starts in the home and is passed on to family members. Next in the hierarchy are neighbours, village elders and finally, traditional healers being the most knowledgeable. For primary health care this hierarchy is actively followed in seeking remedies for ailments. This study was a survey of medicinal plant knowledge from family members of 1(st) year medical students registered at Walter Sisulu University. A total of 206 first year medical students participated in this study in 2010 and 2011. Results revealed 47 species used as home remedies, 32% of which are food plants. Leaves and roots were reported as most commonly used. The top five ailments managed at home were gastrointestinal problems (25 plants), wounds (19 plants), respiratory tract problems (19 plants), infections, including sexually transmitted diseases (19 plants) and pain including headaches (19 plants). Chronic diseases such as hypertension, diabetes, cancer and reproductive ailments also formed a large group of diseases self-managed at home (29 plants). Family members hold knowledge of medicinal plant use. From this study, first year medical students were made aware of the relationship between common ailments and associated home remedies. This study forms a basis for further study of medicinal plants to validate their use as medicinal remedies.

APPLICATION OF PLANT AND EARTHWORM BIOASSAYS TO EVALUATE REMEDIATION OF A LEAD-CONTAMINATED SOIL

EPA Science Inventory

Earthworm acute toxicity, plant seed germination/root elongation (SG/RE) and plant genotoxicity bioassays were employed to evaluate the remediation of a lead-contaminated soil. The remediation involved removal of heavy metals by a soil washing/soil leaching treatment process. A p...

Natural remediation of an unremediated soil twelve years after a mine accident: trace element mobility and plant composition.

PubMed

Burgos, Pilar; Madejón, Paula; Madejón, Engracia; Girón, Ignacio; Cabrera, Francisco; Murillo, José Manuel

2013-01-15

The long-term influence of a mine spill in soil was studied 12 years after the Aznalcóllar accident. Soils where the pyritic sludge was not removed, a fenced plot established for research purposes (2000 m(2)) and soils where the process of remediation was accomplished successfully were sampled and studied in detail. Soils were characterized at different depths, down to 100 cm depth, determining chemical parameters and total concentrations of major and trace elements. Moreover plants colonizing remediated (RE) and non remediated (NRE) soils were also analysed attending their potential risk for herbivores. Strong acidification was observed in the NRE soil except in surface (0-10 cm). The progressive colonization of natural vegetation, more than 90% of the fenced plot covered by plants, could facilitate this increased pH values in the top soil (pH 6). In the NRE soil, the successive oxidation and hydrolysis of sulphide in the deposited sludge on the surface after the accident resulted in a re-dissolution of the most mobile element (Cd, Cu and Zn) and a penetration to deeper layers. Trace element concentrations in plants growing in the NRE soil showed normal contents for higher plants and tolerable for livestock. Nitrogen and mineral nutrients were of the same order in both soils, and also normal for high plants and adequate for animal nutrition. Despite of the natural remediation of the NRE soil, results demonstrate that the remediation tasks carried out in all the area, the Guadiamar Green Corridor at present, were necessary to avoid the leaching of the most mobile elements and minimize the risk of contamination of groundwater sources, many of them close to the Doñana National Park. Copyright © 2012 Elsevier Ltd. All rights reserved.

Mercury Remediation Technology Development for Lower East Fork Poplar Creek - FY 2015 Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peterson, Mark J.; Brooks, Scott C.; Mathews, Teresa J.

2016-04-01

Mercury remediation is a high priority for the US Department of Energy (DOE) Oak Ridge Office of Environmental Management (OREM) because of large historical losses of mercury within buildings and to soils and surface waters at the Y-12 National Security Complex (Y-12). Because of the extent of mercury losses and the complexities of mercury transport and fate in the downstream environment, the success of conventional options for mercury remediation in lower East Fork Poplar Creek (EFPC) is uncertain. A phased, adaptive management approach to remediation of surface water includes mercury treatment actions at Y-12 in the short-term and research andmore » technology development (TD) to evaluate longer-term solutions in the downstream environment (US Department of Energy 2014b).« less

22 CFR 505.12 - Civil remedies and criminal penalties.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Civil remedies and criminal penalties. 505.12 Section 505.12 Foreign Relations BROADCASTING BOARD OF GOVERNORS PRIVACY ACT REGULATION § 505.12 Civil.... Under the conditions of 5 U.S.C. 552a(g), you may seek judicial review of the Agency's refusal to amend...

76 FR 26301 - Decision To Evaluate a Petition To Designate a Class of Employees From the Y-12 Plant in Oak...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-06

... evaluation, is as follows: Facility: Y-12 Plant. Location: Oak Ridge, TN. Job Titles and/or Job Duties: All... Analysis and Support, National Institute for Occupational Safety and Health (NIOSH), 4676 Columbia Parkway...

Mercury Remediation Technology Development for Lower East Fork Poplar Creek - FY 2016 Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dickson, Johnbull O.; Smith, John G.; Mehlhorn, Tonia L.

2017-07-01

Mercury remediation is a high priority for the US Department of Energy (DOE) Oak Ridge Office of Environmental Management (OREM), especially at and near the Y-12 National Security Complex (Y-12) where historical mercury use has resulted in contaminated buildings, soils, and downstream surface waters. To address mercury contamination of East Fork Poplar Creek (EFPC), the DOE has adopted a phased, adaptive management approach to remediation, which includes mercury treatment actions at Y-12 in the short-term and research and technology development (TD) to evaluate longer-term solutions in the downstream environment (US Department of Energy 2014).

Cosmetics and herbal remedies with Compositae plant extracts - are they tolerated by Compositae-allergic patients?

PubMed

Paulsen, Evy; Chistensen, Lars P; Andersen, Klaus E

2008-01-01

Compositae-sensitive patients are routinely warned against topical use of Compositae-containing cosmetics and herbal remedies. However, the risk of elicitation of dermatitis in presensitized persons is unknown. The main aim of this study was to assess the significance of direct plant allergen contact via Compositae-derived cosmetics and herbal remedies in Compositae-allergic patients with special reference to arnica (Arnica montana) and German chamomile (Chamomilla recutita). 8 of 12 chamomile-sensitive patients tested positive to chamomile-containing preparations, including tea, creams, ointments, and oil. 5 of 6 arnica-sensitive persons tested positive to arnica-based products. When the group was patch tested with cosmetic and/or herbal product ingredients, plant allergens elicited positive reactions most frequently, but fragrances, emulsifiers, and preservatives tested positive as well. Plant allergens were mainly derived from Compositae, but avocado oil, and Hamamelis virginiana tincture were unexpectedly detected as sensitizers too. Chemical analyses indicated that the Compositae allergens were both sesquiterpene lactones and other naturally occurring compounds. In conclusion, Compositae-allergic persons should be warned against topical use of Compositae-containing products, not only because of the plant allergens, but also because of allergenic cream constituents that may cause reactions in the group of patients who have multiple contact allergies beside the Compositae allergy.

The Interaction between Plants and Bacteria in the Remediation of Petroleum Hydrocarbons: An Environmental Perspective.

PubMed

Gkorezis, Panagiotis; Daghio, Matteo; Franzetti, Andrea; Van Hamme, Jonathan D; Sillen, Wouter; Vangronsveld, Jaco

2016-01-01

Widespread pollution of terrestrial ecosystems with petroleum hydrocarbons (PHCs) has generated a need for remediation and, given that many PHCs are biodegradable, bio- and phyto-remediation are often viable approaches for active and passive remediation. This review focuses on phytoremediation with particular interest on the interactions between and use of plant-associated bacteria to restore PHC polluted sites. Plant-associated bacteria include endophytic, phyllospheric, and rhizospheric bacteria, and cooperation between these bacteria and their host plants allows for greater plant survivability and treatment outcomes in contaminated sites. Bacterially driven PHC bioremediation is attributed to the presence of diverse suites of metabolic genes for aliphatic and aromatic hydrocarbons, along with a broader suite of physiological properties including biosurfactant production, biofilm formation, chemotaxis to hydrocarbons, and flexibility in cell-surface hydrophobicity. In soils impacted by PHC contamination, microbial bioremediation generally relies on the addition of high-energy electron acceptors (e.g., oxygen) and fertilization to supply limiting nutrients (e.g., nitrogen, phosphorous, potassium) in the face of excess PHC carbon. As an alternative, the addition of plants can greatly improve bioremediation rates and outcomes as plants provide microbial habitats, improve soil porosity (thereby increasing mass transfer of substrates and electron acceptors), and exchange limiting nutrients with their microbial counterparts. In return, plant-associated microorganisms improve plant growth by reducing soil toxicity through contaminant removal, producing plant growth promoting metabolites, liberating sequestered plant nutrients from soil, fixing nitrogen, and more generally establishing the foundations of soil nutrient cycling. In a practical and applied sense, the collective action of plants and their associated microorganisms is advantageous for remediation of PHC

The Interaction between Plants and Bacteria in the Remediation of Petroleum Hydrocarbons: An Environmental Perspective

PubMed Central

Gkorezis, Panagiotis; Daghio, Matteo; Franzetti, Andrea; Van Hamme, Jonathan D.; Sillen, Wouter; Vangronsveld, Jaco

2016-01-01

Widespread pollution of terrestrial ecosystems with petroleum hydrocarbons (PHCs) has generated a need for remediation and, given that many PHCs are biodegradable, bio- and phyto-remediation are often viable approaches for active and passive remediation. This review focuses on phytoremediation with particular interest on the interactions between and use of plant-associated bacteria to restore PHC polluted sites. Plant-associated bacteria include endophytic, phyllospheric, and rhizospheric bacteria, and cooperation between these bacteria and their host plants allows for greater plant survivability and treatment outcomes in contaminated sites. Bacterially driven PHC bioremediation is attributed to the presence of diverse suites of metabolic genes for aliphatic and aromatic hydrocarbons, along with a broader suite of physiological properties including biosurfactant production, biofilm formation, chemotaxis to hydrocarbons, and flexibility in cell-surface hydrophobicity. In soils impacted by PHC contamination, microbial bioremediation generally relies on the addition of high-energy electron acceptors (e.g., oxygen) and fertilization to supply limiting nutrients (e.g., nitrogen, phosphorous, potassium) in the face of excess PHC carbon. As an alternative, the addition of plants can greatly improve bioremediation rates and outcomes as plants provide microbial habitats, improve soil porosity (thereby increasing mass transfer of substrates and electron acceptors), and exchange limiting nutrients with their microbial counterparts. In return, plant-associated microorganisms improve plant growth by reducing soil toxicity through contaminant removal, producing plant growth promoting metabolites, liberating sequestered plant nutrients from soil, fixing nitrogen, and more generally establishing the foundations of soil nutrient cycling. In a practical and applied sense, the collective action of plants and their associated microorganisms is advantageous for remediation of PHC

Evaluation of Calendar Year 1997 Groundwater and Surface Water Quality Data For The Chestnut Ridge Hydrogeologic Regime At The U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, S.B.

1998-09-01

This report presents an evaluation of the groundwater monitoring data obtained in the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime) during calendar year (CY) 1997. The Chestnut Ridge Regime encompasses a section of Chestnut Ridge bordered by the U.S. Department of Energy (DOE) Y-12 Plant in Bear Creek Valley (BCV) to the north, Scarboro Road to the eas~ Bethel Valley Road to the south, and an unnamed drainage basin southwest of the Y-12 Plant (Figure 1). Groundwater quality monitoring is performed at hazardous and nonhazardous waste management facilities in the regime under the auspices of the Y-12 Plant Groundwater Protectionmore » Program (GWPP). The CY 1997 monitoring data are presented in Calendar Year 1997 Annual Groundwater Monitoring Report for the Chestnut Ridge Hydrogeolo~"c Regime at the US. Department of Energy Y-12 Plant, Oak Ridge, Tennessee (MA Technical Services, Inc. 1998), which also presents results of site-specific monitoring data evaluations required under the Resource Conservation and Recovery Act (RCIL4) post-closure permit (PCP) for the Chestnut Ridge Regime« less

USING PLANTS TO REMEDIATE PETROLEUM-CONTAMINATED SOIL: PROJECT CONTINUATION

EPA Science Inventory

Crude oil contamination of soil often occurs adjacent to wellheads and storage facilities. Phytoremediation is a promising tool that can be used to remediate such sites and uses plants and agronomic techniques to enhance biodegradation of hydrocarbons. This project has conduct...

Superfund record of decision (EPA Region 6): Longhorn Army Ammunition Plant, IHAAP 12 and 16 Landfills, Karnack, TX, September 27, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This decision document presents the selected Early Interim Remedial Action for the LHAAP 12 and 16 landfills, Longhorn Army Ammunition Plant (LHAAP), Karnack, Texas. The Record of Decision for the sites addresses an Early Interim Remedial Action. The selected remedy consists of a multilayer landfill cap section which includes the following components: Foundation soil layer, Sodium Bentonite Geocomposite Liner, Geosynthetic Membrane Liner, Final soil cover, and Perimeter berms and drainage swales.

Remediation of blowouts by clonal plants in Maqu degraded alpine grasslands of northwest China.

PubMed

Kang, JianJun; Zhao, WenZhi; Zhao, Ming

2017-03-01

The sand-fixation of plants is considered to be the most effective and fundamental measure in desertification control in many arid and semi-arid regions. Carex brunnescens (Carex spp) and Leymus secalinus (Leymus), two perennial clonal herbs native to the Maqu degraded alpine areas of northwest China, are dominant and constructive species in active sand dunes that have excellent adaptability to fix sand dunes found to date. In order to study the ability and mechanism of sandland blowout remediation by two clone plants C. brunnescens and L. secalinus, the artificially emulated blowouts were set up in the populations of two clonal plants in the field. The results showed that both C. brunnescens and L. secalinus produced more new ramets in the artificially emulated blowouts than in the natural conditions, suggesting that the two clonal plants had strong ability in blowouts remediation; while the biomass, number of leaves and height of new ramets in the artificially emulated blowouts were less than in the natural conditions due to the restriction of poor nutrients in the artificially emulated blowouts. The ability of blowouts remediation by C. brunnescens was stronger than L. secalinus, as it generated more new ramets than L. secalinus in the process of blowouts remediation. The new ramets of L. secalinus in the blowouts remediation were mainly generated by the buds in the rhizomes which spread from outside of the blowouts; while those of C. brunnescens were generated both by the buds in the rhizomes which spread from outside, and by the buds in the rhizomes inside which were freed from dormancy in the deeper soil under wind erosion conditions. These findings suggest that through rapid clonal expansion capability, C. brunnescens and L. secalinus exhibited strong ability in blowouts remediation which can be one of the most effective strategies to restore and reconstruct degraded vegetations in Maqu alpine areas of northwest China.

The effects of Pantoea sp. strain Y4-4 on alfalfa in the remediation of heavy-metal-contaminated soil, and auxiliary impacts of plant residues on the remediation of saline-alkali soils.

PubMed

Li, Shuhuan; Wang, Jie; Gao, Nanxiong; Liu, Lizhu; Chen, Yahua

2017-04-01

The plant-growth-promoting rhizobacterium (PGPR) Y4-4 was isolated from plant rhizosphere soil and identified as Pantoea sp. by 16S rRNA sequence analysis. The effects of strain Y4-4 on alfalfa grown in heavy-metals-contaminated soil was investigated using a pot experiment. In a Cu-rich environment, the shoot dry mass and total dry mass of plants inoculated with strain Y4-4 increased by 22.6% and 21%, and Cu accumulation increased by 15%. In a Pb-Zn-rich environment, the shoot dry mass and total dry mass of plants inoculated with strain Y4-4 increased by 23.4% and 22%, and Zn accumulation increased by 30.3%. In addition, the salt tolerance and biomass of wheat seedlings could be improved by applying strain Y4-4 mixed with plant residue as a result of the Cu-rich plant residues providing copper nutrition to wheat. This study offers an efficient PGPR with strong salt tolerance and a safe strategy for the post-treatment of plant residue.

Monitored Natural Attenuation as a Remediation Strategy for Nuclear Power Plant Applications

NASA Astrophysics Data System (ADS)

Kim, K.; Bushart, S.

2009-12-01

A NRC Information Notice (IN 2006-13) was produced to inform holders of nuclear operating licenses “of the occurrence of radioactive contamination of ground water at multiple facilities due to undetected leakage from facility structures, systems, or components (SSCs) that contain or transport radioactive fluids” so that they could consider actions, as appropriate, to avoid similar problems. To reinforce their commitment to environmental stewardship the nuclear energy industry has committed to improving management of situations that have the potential to lead to the inadvertent release of radioactive fluids. This Industry Groundwater Protection Initiative, finalized in June 2007 as [NEI 07-07], calls for implementation and improvement of on-site groundwater monitoring programs and enhanced communications with stakeholders and regulators about situations related to inadvertent releases. EPRI developed its Groundwater Protection Program to provide the nuclear energy industry with the technical support needed to implement the Industry Groundwater Initiative. An objective of the EPRI Groundwater Protection Program is to provide the nuclear industry with technically sound guidance for implementing and enhancing on-site groundwater monitoring programs. EPRI, in collaboration with the EPRI Groundwater Protection Committee of utility members, developed the EPRI Groundwater Protection Guidelines for Nuclear Power Plants (EPRI Report 1015118, November 2007), which provides site-specific guidance for implementing a technically sound groundwater monitoring program. The guidance applies a graded approach for nuclear plants to tailor a technically effective and cost efficient groundwater monitoring program to the site’s hydrogeology and risk for groundwater contamination. As part of the Groundwater Protection Program, EPRI is also investigating innovative remediation technologies for addressing low-level radioactive contamination in soils and groundwater at nuclear power

Resource Conservation and Recovery Act (RCRA) Part B Permit Application for Production Associated Units at the Oak Ridge Y-12 Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This is the RCRA required permit application for Radioactive and Hazardous Waste Management at the Oak Ridge Y-12 Plant for the following units: Building 9206 Container Storage Unit; Building 9212 Container Storage Unit; Building 9720-12 Container Storage Unit; Cyanide Treatment Unit. All four of these units are associated with the recovery of enriched uranium and other metals from wastes generated during the processing of nuclear materials.

12 CFR 24.7 - Examination, records, and remedial action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Examination, records, and remedial action. 24.7 Section 24.7 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY COMMUNITY AND ECONOMIC DEVELOPMENT ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE INVESTMENTS § 24.7...

[Use of medicinal plants as home remedies in Primary Health Care in Blumenau - State of Santa Catarina, Brazil].

PubMed

Zeni, Ana Lúcia Bertarello; Parisotto, Amanda Varnier; Mattos, Gerson; Helena, Ernani Tiaraju de Santa

2017-08-01

An increase in the use of alternative therapeutic practices has been observed in the past decade, especially in medicinal plants, herbal and home remedies, which has been supported by policies within the scope of the Unified Health System (SUS). This study investigated the use of home remedies by users of Primary Health Care in Blumenau, State of Santa Catarina. It is a cross-sectional, observational and epidemiological study, the data for which were obtained via a questionnaire applied to 701 individuals. An unconditional logistic regression model was used to estimate the association between the use of home remedies and socio-demographic and medical care variables. It was observed that 21.9% of the sample use home remedies and medicinal plants grown in the back yard are the remedies of choice. Lemon balm, chamomile, peppermint and lime were the remedies most frequently mentioned. The use of home remedies was associated with the female gender, older age and the Family Health Strategy care model. The results supported that medicinal plants are used by the population as a therapeutic alternative option. However, it is necessary that primary care services ensure both access to natural products and supply qualified professionals to give instructions regarding the correct usage of home remedies.

Remedial action suitability for the Cornhusker Army Ammunition Plant site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nonavinakere, S.; Rappa, P. III

1995-12-31

Numerous Department of Defense (DOD) sites across the nation are contaminated with explosive wastes due to munitions production during World War II, Korean Conflict and Vietnam Conflict. Production activities included explosives manufacturing, loading, packing, assembling, machining, casting and curing. Contaminants often present at these sites include TNT, RDX, HMX, Tetryl 2,4-DNT, 2,6-DNT, 1,3-DNB, 1,3,5-TNB and nitrobenzene. The Cornhusker Army Ammunition Plant (CAAP) is one such DOD site that has been determined to be contaminated with explosives. The CAAP is located approximately 2 miles west of the City of Grand Island in Hall County, Nebraska. The plant produced artillery, bombs, boosters,more » supplementary charges and various other experimental explosives. The purpose of this paper is to provide an overview of the site background, review of the remedial alternatives evaluation process and rationale behind the selection of present remedial action.« less

Soil Management Plan for the Oak Ridge Y-12 National Security Complex Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2005-03-02

This Soil Management Plan applies to all activities conducted under the auspices of the National Nuclear Security Administration (NNSA) Oak Ridge Y-12 National Security Complex (Y-12) that involve soil disturbance and potential management of waste soil. The plan was prepared under the direction of the Y-12 Environmental Compliance Department of the Environment, Safety, and Health Division. Soil disturbances related to maintenance activities, utility and building construction projects, or demolition projects fall within the purview of the plan. This Soil Management Plan represents an integrated, visually oriented, planning and information resource tool for decision making involving excavation or disturbance of soilmore » at Y-12. This Soil Management Plan addresses three primary elements. (1) Regulatory and programmatic requirements for management of soil based on the location of a soil disturbance project and/or the regulatory classification of any contaminants that may be present (Chap. 2). Five general regulatory or programmatic classifications of soil are recognized to be potentially present at Y-12; soil may fall under one or more these classifications: (a) Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) pursuant to the Oak Ridge Reservation (ORR) Federal Facilities Agreement; (b) Resource Conservation and Recovery Act (RCRA); (c) RCRA 3004(u) solid waste managements units pursuant to the RCRA Hazardous and Solid Waste Amendments Act of 1984 permit for the ORR; (d) Toxic Substances and Control Act-regulated soil containing polychlorinated biphenyls; and (e) Radiologically contaminated soil regulated under the Atomic Energy Act review process. (2) Information for project planners on current and future planned remedial actions (RAs), as prescribed by CERCLA decision documents (including the scope of the actions and remedial goals), land use controls implemented to support or maintain RAs, RCRA post-closure regulatory requirements

Calendar years 1989 and 1990 monitoring well installation program Y-12 plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-10-01

This report documents the well-construction activities at the Y-12 Plant in Oak Ridge, Tennessee during 1989 and 1990. The well- construction program consisted of installing seventy-five monitoring wells. Geologists from ERCE (formally the Engineering, Design and Geosciences Group) and Martin Marietta Energy Systems (Energy Systems), supervised and documented well-construction activities and monitored for health and safety concerns. Sixty-seven monitoring wells were installed under the supervision of an ERCE geologist from March 1989 to September 1990. Beginning in September 1990, Energy Systems supervised drilling activities for eight monitoring wells, the last of which was completed in December 1990. 9 refs., 3more » figs., 2 tabs.« less

Remedial Investigation Report on Bear Creek Valley Operable Unit 2 (Rust Spoil Area, Spoil Area 1, and SY-200 Yard) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Volume 1, Main text

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-01-01

This report on the BCV OU 2 at the Y-12 Plant, was prepared in accordance with requirements under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) for reporting the results of a site characterization for public review. It provides the Environmental Restoration Program with information about the results of the 1993 investigation. It includes information on risk assessments that have evaluated impacts to human health and the environment. Field activities included collection of subsurface soil samples, groundwater and surface water samples, and sediments and seep at the Rust Spoil Area (RSA), SY-200 Yard, and SA-1.

Calendar year 1996 annual groundwater monitoring report for the Chestnut Ridge Hydrogeologic Regime at the U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-02-01

This annual monitoring report contains groundwater and surface water monitoring data obtained in the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime) during calendar year (CY) 1996. The Chestnut Ridge Regime encompasses a section of Chestnut Ridge west of Scarboro Road and east of an unnamed drainage feature southwest of the US Department of Energy (DOE) Oak Ridge Y-12 Plant (unless otherwise noted, directions are in reference to the Y-12 Plant administrative grid). The Chestnut Ridge Regime contains several sites used for management of hazardous and nonhazardous wastes associated with plant operations. Groundwater and surface water quality monitoring associated with thesemore » waste management sites is performed under the auspices of the Y-12 Plant Groundwater Protection Program (GWPP). Included in this annual monitoring report are the groundwater monitoring data obtained in compliance with the Resource Conservation and Recovery Act (RCRA) Post-Closure Permit for the Chestnut Ridge Regime (post-closure permit) issued by the Tennessee Department of Environment and Conservation (TDEC) in June 1996. Besides the signed certification statement and the RCRA facility information summarized below, condition II.C.6 of the post-closure permit requires annual reporting of groundwater monitoring activities, inclusive of the analytical data and results of applicable data evaluations, performed at three RCRA hazardous waste treatment, storage, or disposal (TSD) units: the Chestnut Ridge Sediment Disposal Basin (Sediment Disposal Basin), the Chestnut Ridge Security Pits (Security Pits), and Kerr Hollow Quarry.« less

Engineering a Catabolic Pathway in Plants for the Degradation of 1,2-Dichloroethane1[OA

PubMed Central

Mena-Benitez, Gilda L.; Gandia-Herrero, Fernando; Graham, Stuart; Larson, Tony R.; McQueen-Mason, Simon J.; French, Christopher E.; Rylott, Elizabeth L.; Bruce, Neil C.

2008-01-01

Plants are increasingly being employed to clean up environmental pollutants such as heavy metals; however, a major limitation of phytoremediation is the inability of plants to mineralize most organic pollutants. A key component of organic pollutants is halogenated aliphatic compounds that include 1,2-dichloroethane (1,2-DCA). Although plants lack the enzymatic activity required to metabolize this compound, two bacterial enzymes, haloalkane dehalogenase (DhlA) and haloacid dehalogenase (DhlB) from the bacterium Xanthobacter autotrophicus GJ10, have the ability to dehalogenate a range of halogenated aliphatics, including 1,2-DCA. We have engineered the dhlA and dhlB genes into tobacco (Nicotiana tabacum ‘Xanthi’) plants and used 1,2-DCA as a model substrate to demonstrate the ability of the transgenic tobacco to remediate a range of halogenated, aliphatic hydrocarbons. DhlA converts 1,2-DCA to 2-chloroethanol, which is then metabolized to the phytotoxic 2-chloroacetaldehyde, then chloroacetic acid, by endogenous plant alcohol dehydrogenase and aldehyde dehydrogenase activities, respectively. Chloroacetic acid is dehalogenated by DhlB to produce the glyoxylate cycle intermediate glycolate. Plants expressing only DhlA produced phytotoxic levels of chlorinated intermediates and died, while plants expressing DhlA together with DhlB thrived at levels of 1,2-DCA that were toxic to DhlA-expressing plants. This represents a significant advance in the development of a low-cost phytoremediation approach toward the clean-up of halogenated organic pollutants from contaminated soil and groundwater. PMID:18467461

Evaluation of fish kills during November 1986 and July 1987 in upper East Fork Poplar Creek near the Y-12 Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryon, M.G.; Loar, J.M.; Southworth, G.R.

1990-09-01

The Environmental Sciences Division (ESD) investigated two fish kills that occurred on November 21, 1986, and July 9, 1987, in upper East Fork Poplar Creek at the outfall of New Hope Pond (NHP) below the Oak Ridge Y-12 Plant. Investigative procedures included sampling of water at the inlet and outfall of NHP for water quality, examination of operating procedures at the Y-12 Plant and in the biomonitoring program that may have adversely affected the fish populations, review of results of concurrent ambient toxicity tests of the inlet and outfall water of NHP, autopsy investigations of the cause of death ofmore » the stonerollers, and laboratory experimentation to evaluate potential causes. The investigations revealed that the cause of death was bacterial hemorrhagic septicemia caused by Aeromonas hydrophila, which is a stress-mediated disease. The specific stressor responsible for the outbreak of the disease was not identified. Several possible stresses were indicated, including elevated concentrations of mercury and chlorine, excessive electroshocking activity, and elevated levels of the pathogen. Cumulative stress due to the combination of several factors was also suggested. Elevated temperatures and overcrowding may have enhanced the spread of the epizootic but were not the primary causes. The impact on the stoneroller population below NHP was not ecologically significant. 23 refs., 3 figs., 12 tabs.« less

Developing microbe-plant interactions for applications in plant-growth promotion and disease control, production of useful compounds, remediation, and carbon sequestration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, C.H.; Bernard, S.; Andersen, G.L.

2009-03-01

Interactions between plants and microbes are an integral part of our terrestrial ecosystem. Microbe-plant interactions are being applied in many areas. In this review, we present recent reports of applications in the areas of plant-growth promotion, biocontrol, bioactive compound and biomaterial production, remediation and carbon sequestration. Challenges, limitations and future outlook for each field are discussed.

Quantification of prairie restoration for phytostability at a remediated defense plant.

PubMed

Franson, Raymond L; Scholes, Chad M

2011-01-01

In June 2008 and 2009, cover, density, and species diversity were measured on two areas of the prairie at the U. S. Department of Energy Weldon Spring Site to begin quantification of the prairie establishment and the effects of a prairie burn. Sampling began by testing for the most appropriate transect length (cover) and quadrat size (density) for quantification of vegetation. Total cover increased in the first growing season after burning. Conversely, total cover decreased in the unburned area in one year. The trend in litter cover is the opposite with litter decreasing after burning, but increasing in one year in the unburned area. Bare ground decreased in one year in the unburned area, but was unchanged after burning. Species diversity tripled after fire, but was unchanged in one year in the unburned area. The results show that litter and fire both affect plant cover. If land reclamation activities are to be an integral part of hazardous waste remediation at contaminated sites, then the success of reclamation efforts needs to be quantified along with success criteria for waste remediation of the sites. The results show that plant cover can be easily quantified, but that density measures are more biased which makes it more difficult to achieve adequate sample size for plant density.

Alleviation of Heavy Metal Stress in Plants and Remediation of Soil by Rhizosphere Microorganisms

PubMed Central

Mishra, Jitendra; Singh, Rachna; Arora, Naveen K.

2017-01-01

Increasing concentration of heavy metals (HM) due to various anthropogenic activities is a serious problem. Plants are very much affected by HM pollution particularly in contaminated soils. Survival of plants becomes tough and its overall health under HM stress is impaired. Remediation of HM in contaminated soil is done by physical and chemical processes which are costly, time-consuming, and non-sustainable. Metal–microbe interaction is an emerging but under-utilized technology that can be exploited to reduce HM stress in plants. Several rhizosphere microorganisms are known to play essential role in the management of HM stresses in plants. They can accumulate, transform, or detoxify HM. In general, the benefit from these microbes can have a vast impact on plant’s health. Plant–microbe associations targeting HM stress may provide another dimension to existing phytoremediation and rhizoremediation uses. In this review, applied aspects and mechanisms of action of heavy metal tolerant-plant growth promoting (HMT-PGP) microbes in ensuring plant survival and growth in contaminated soils are discussed. The use of HMT-PGP microbes and their interaction with plants in remediation of contaminated soil can be the approach for the future. This low input and sustainable biotechnology can be of immense use/importance in reclaiming the HM contaminated soils, thus increasing the quality and yield of such soils. PMID:28932218

Underground storage tank management plan, Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-09-01

The Underground Storage Tank (UST) Program at the Oak Ridge Y-12 Plant was established to locate UST systems at the facility and to ensure that all operating UST systems are free of leaks. UST systems have been removed or upgraded in accordance with Tennessee Department of Environment and Conservation (TDEC) regulations and guidance. With the closure of a significant portion of the USTs, the continuing mission of the UST Management Program is to manage the remaining active UST systems and continue corrective actions in a safe regulatory compliant manner. This Program outlines the compliance issues that must be addressed, reviewsmore » the current UST inventory and compliance approach, and presents the status and planned activities associated with each UST system. The UST Program provides guidance for implementing TDEC regulations and guidelines for petroleum UST systems. The plan is divided into three major sections: (1) regulatory requirements, (2) active UST sites, and (3) out-of-service UST sites. These sections describe in detail the applicable regulatory drivers, the UST sites addressed under the Program, and the procedures and guidance for compliance.« less

Y-12 Site Sustainability Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spencer, Charles G

2012-12-01

The accomplishments to date and the long-range planning of the Y-12 Energy Management and Sustainability and Stewardship programs support the U.S. Department of Energy (DOE) and the National Nuclear Security Administration (NNSA) vision for a commitment to energy effi ciency and sustainability and to achievement of the Guiding Principles. Specifi cally, the Y-12 vision is to support the Environment, Safety and Health Policy and the DOE Strategic Sustainability Performance Plan, while promoting overall sustainability and reduction of greenhouse gas emissions. The mission of the Y-12 Energy Management program is to incorporate energy-effi cient technologies site-wide and to position Y-12 tomore » meet NNSA energy requirement needs through 2025 and beyond. The plan addresses greenhouse gases, buildings, fleet management, water use, pollution prevention, waste reduction, sustainable acquisition, electronic stewardship and data centers, site innovation and government-wide support.« less

Progress and Future Plans for Mercury Remediation at the Y-12 National Security Complex, Oak Ridge, Tennessee - 13059

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilkerson, Laura O.; DePaoli, Susan M.; Turner, Ralph

2013-07-01

The U.S. Department of Energy (DOE), along with the Tennessee Department of Environment and Conservation (TDEC) and the U.S. Environmental Protection Agency (EPA), has identified mercury contamination at the Y-12 National Security Complex (Y-12) as the highest priority cleanup risk on the Oak Ridge Reservation (ORR). The historic loss of mercury to the environment dwarfs any other contaminant release on the ORR. Efforts over the last 20 years to reduce mercury levels leaving the site in the surface waters of Upper East Fork Poplar Creek (UEFPC) have not resulted in a corresponding decrease in mercury concentrations in fish. Further reductionsmore » in mercury surface water concentrations are needed. Recent stimulus funding through the American Recovery and Reinvestment Act of 2009 (ARRA) has supported several major efforts involving mercury cleanup at Y-12. Near-term implementation activities are being pursued with remaining funds and include design of a centrally located mercury treatment facility for waterborne mercury, treatability studies on mercury-contaminated soils, and free mercury removal from storm drains. Out-year source removal will entail demolition/disposal of several massive uranium processing facilities along with removal and disposal of underlying contaminated soil. As a National Priorities List (NPL) site, cleanup is implemented under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and directed by the Federal Facility Agreement (FFA) between DOE, EPA, and TDEC. The CERCLA process is followed to plan, reach approval, implement, and monitor the cleanup. (authors)« less

Determination of Oxalate Content in Herbal Remedies and Dietary Supplements Based on Plant Extracts.

PubMed

Siener, Roswitha; López-Mesas, Montserrat; Valiente, Manuel; Blanco, Francisco

2016-02-01

Lifestyle, especially diet, is a prominent risk factor that affects the formation of calcium oxalate stones. Urinary oxalate excretion is directly related to the amount of oral intake and intestinal absorption rate of oxalate. This work evaluated the possibility of increasing oxalate ingestion, which could lead to secondary hyperoxaluria, associated with the intake of herbal remedies and dietary supplements containing plant extracts. A wide variety of 17 commercially available drugs and dietary supplements were analyzed using ion chromatography. The results showed remarkable differences in oxalate contents of the extracts. Total oxalate concentrations ranged from 0.03 to 2.2 mg/g in solid samples and from 0.005 to 0.073 mg/mL in liquid samples. The selected herbal remedies and dietary supplements containing plant extracts represent only a low risk for calcium oxalate stone formers, if the recommended daily dose is not exceeded.

Arsenic: A Review of the Element's Toxicity, Plant Interactions, and Potential Methods of Remediation.

PubMed

Hettick, Bryan E; Cañas-Carrell, Jaclyn E; French, Amanda D; Klein, David M

2015-08-19

Arsenic is a naturally occurring element with a long history of toxicity. Sites of contamination are found worldwide as a result of both natural processes and anthropogenic activities. The broad scope of arsenic toxicity to humans and its unique interaction with the environment have led to extensive research into its physicochemical properties and toxic behavior in biological systems. The purpose of this review is to compile the results of recent studies concerning the metalloid and consider the chemical and physical properties of arsenic in the broad context of human toxicity and phytoremediation. Areas of focus include arsenic's mechanisms of human toxicity, interaction with plant systems, potential methods of remediation, and protocols for the determination of metals in experimentation. This assessment of the literature indicates that controlling contamination of water sources and plants through effective remediation and management is essential to successfully addressing the problems of arsenic toxicity and contamination.

Enhanced and complete removal of phenylurea herbicides by combinational transgenic plant-microbial remediation.

PubMed

Yan, Xin; Huang, Jun-Wei; Xu, Xi-Hui; Chen, Dian; Xie, Xiang-Ting; Tao, Qing; He, Jian; Jiang, Jian-Dong

2018-05-11

The synergistic relationships between plants and their rhizospheric microbes can be used to develop a combinational bioremediation method, overcoming the constraints of individual phytoremediation or bioaugmentation method. Here, we provide a combinational transgenic plant-microbial remediation system for a more efficient removal of phenylurea herbicides (PHs) from contaminated-sites. The transgenic Arabidopsis thaliana synthesizing the bacterial N -demethylase PdmAB in the chloroplast was developed. The constructed transgenic Arabidopsis exhibited significant tolerance to isoproturon (IPU), a typical PH, and it took up the IPU through roots and transported to leaves, where the majority of the IPU was demethylated to 3-(4-isopropylphenyl)-1-methylurea (MDIPU). The produced intermediate was released outside of roots and further metabolized by the combinationally inoculated MDIPU-mineralizing bacterium Sphingobium sp. strain 1017-1 in the rhizosphere, resulting in an enhanced and complete removal of IPU from soil. Mutual benefits were built for both transgenic Arabidopsis and strain 1017-1. The transgenic Arabidopsis offered strain 1017-1 a suitable accommodation and in return, the latter protected the plant from the phytotoxicity of MDIPU. The biomass of the transgenic Arabidopsis and the residence of the inoculated degrading microbes in the combinational treatment increased significantly compared to that in their respective individual transgenic plant treatment or bioaugmentation treatment. The influence of the structure of bacterial community by combinational treatment was between that of the two individual treatments. Overall, the combination of two approaches, phytoremediation by transgenic plants and bioaugmentation with intermediate-mineralizing microbes in the rhizosphere, represents an innovative strategy for the enhanced and complete remediation of pollutant-contaminated sites. IMPORTANCE Phytoremediation of organic pollutant-contaminated sites using

Remedial investigation work plan for Bear Creek Valley Operable Unit 4 (shallow groundwater in Bear Creek Valley) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-07-01

To effectively evaluate the cumulative impact of releases from multiple sources of contamination, a structured approach has been adopted for Oak Ridge Reservation (ORR) based on studies of the groundwater and surface water separate from studies of the sources. Based on the realization of the complexity of the hydrogeologic regime of the ORR, together with the fact that there are numerous sources contributing to groundwater contamination within a geographical area, it was agreed that more timely investigations, at perhaps less cost, could be achieved by separating the sources of contamination from the groundwater and surface water for investigation and remediation.more » The result will be more immediate attention [Records of Decision (RODs) for interim measures or removal actions] for the source Operable Units (OUs) while longer-term remediation investigations continue for the hydrogeologic regimes, which are labeled as integrator OUs. This remedial investigation work plan contains summaries of geographical, historical, operational, geological, and hydrological information specific to the unit. Taking advantage of the historical data base and ongoing monitoring activities and applying the observational approach to focus data gathering activities will allow the feasibility study to evaluate all probable or likely alternatives.« less

Remedial Investigation work plan for Bear Creek Valley Operable Unit 4 (shallow groundwater in Bear Creek Valley) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-09-01

To effectively evaluate the cumulative impact of releases from multiple sources of contamination, a structured approach has been adopted for Oak Ridge Reservation (ORR) based on studies of the groundwater and surface water separate from studies of the sources. Based on the realization of the complexity of the hydrogeologic regime of the ORR, together with the fact that there are numerous sources contributing to groundwater contamination within a geographical area, it was agreed that more timely investigations, at perhaps less cost, could be achieved by separating the sources of contamination from the groundwater and surface water for investigation and remediation.more » The result will be more immediate attention [Records of Decision (RODS) for interim measures or removal actions] for the source Operable Units (OUs) while longer-term remediation investigations continue for the hydrogeologic regime`s, which are labeled as integrator OUs. This Remedial Investigation work plan contains summaries of geographical, historical, operational, geological, and hydrological information specific to the unit. Taking advantage of the historical data base and ongoing monitoring activities and applying the observational approach to focus data gathering activities will allow the Feasibility Study to evaluate all probable or likely alternatives.« less

Physicochemical Approaches for the Remediation of Former Manufactured Gas Plant Tars

NASA Astrophysics Data System (ADS)

Hauswirth, S.; Miller, C. T.

2014-12-01

Former manufactured gas plant (FMGP) tars are one of the most challenging non-aqueous phase liquid (NAPL) contaminants to remediate due to their complex chemical composition, high viscosities, and ability to alter wettability. In this work, we investigate several in situ remediation techniques for the removal of tar from porous media. Batch and column experiments were conducted to test the effectiveness of mobilization, solubilization, and chemical oxidation remediation approaches. Alkaline (NaOH), surfactant (Triton X-100), and polymer (xanthan gum) agents were used in various combinations to reduce tar-water interfacial tension, increase flushing solution viscosity, and increase the solubilities of tar components. Base-activated sodium persulfate was used alone and in combination with surfactant to chemically oxidized tar components. The effectiveness of each method was assessed in terms of both removal of PAHs from the system and reduction of dissolved-phase effluent polycyclic aromatic hydrocarbon (PAH) concentrations. In column studies, alkaline-polymer (AP) and alkaline-surfactant-polymer (ASP) solutions efficiently mobilized 81-93% and 95-96% of residual PAHs, respectively, within two pore volumes. The impact of AP flushing on dissolved-phase PAH concentrations was relatively low; however, the concentrations of several low molar mass PAHs were significantly reduced after ASP flushing. Surfactant-polymer (SP) solutions removed over 99% of residual PAHs through a combination of mobilization and solubilization, and reduced the post-remediation, dissolved-phase total PAH concentration by 98.4-99.1%. Degradation of residual PAHs by base-activated sodium persulfate was relatively low (30-50%), and had little impact on dissolved-phase PAH concentrations.

Sampling results, DNAPL monitoring well GW-726, Oak Ridge Y-12 plant, Oak Ridge, Tennessee. Quarterly report, April 1, 1994--September 30, 1994.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-12-31

In January 1990, dense, non aqueous phase liquids (DNAPLs) were discovered at a depth of approximately 274 foot below ground surface along the southern border of the Y-12 Plant Burial Grounds. Immediately after the discovery, an investigation was conducted to assess the occurrence of DNAPL at the site and to make recommendations for further action. This report summarizes purging and sampling activities for one of these multiport wells, GW-726, and presents analytical results for GW-726.

Remediation of Mercury-Contaminated Storm Sewer Sediments from the West End Mercury Area at the Y-12 National Security Complex in Oak Ridge, Tennessee - 12061

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tremaine, Diana; Douglas, Steven G.

2012-07-01

The Y-12 National Security Complex in Oak Ridge, TN has faced an ongoing challenge from mercury entrapped in soils beneath and adjacent to buildings, storm sewers, and process pipelines. Previous actions to reduce the quantity and/or mobilization of mercury-contaminated media have included plugging of building floor drains, cleaning of sediment and sludge from sumps, manholes, drain lines, and storm sewers, lining/relining of storm sewers and replacement of a portion of the storm sewer trunk line, re-routing and removal of process piping, and installation of the Central Mercury Treatment System to capture and treat contaminated sump water. Despite the success ofmore » these actions, mercury flux in the storm sewer out-falls that discharge to Upper East Fork Poplar Creek (UEFPC) continues to pose a threat to long-term water quality. A video camera survey of the storm sewer network revealed several sections of storm sewer that had large cracks, separations, swells, and accumulations of sediment/sludge and debris. The selected remedy was to clean and line the sections of storm sewer pipe that were determined to be primary contributors to the mercury flux in the storm sewer out-falls. The project, referred to as the West End Mercury Area (WEMA) Storm Sewer Remediation Project, included cleaning sediment and debris from over 2,460 meters of storm sewer pipe followed by the installation of nearly 366 meters of cure-in-place pipe (CIPP) liner. One of the greatest challenges to the success of this project was the high cost of disposal associated with the mercury-contaminated sludge and wastewater generated from the storm sewer cleaning process. A contractor designed and operated an on-site wastewater pre-treatment system that successfully reduced mercury levels in 191 cubic meters of sludge to levels that allowed it to be disposed at Nevada Nuclear Security Site (NNSS) disposal cell as a non-hazardous, low-level waste. The system was also effective at pre-treating over 1

19 CFR 12.31 - Plant pests.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Plant pests. 12.31 Section 12.31 Customs Duties U... SPECIAL CLASSES OF MERCHANDISE Wild Animals, Birds, and Insects § 12.31 Plant pests. The importation in a... Agriculture, Animal and Plant Health Inspection Service, Plant Protection and Quarantine Programs of that...

19 CFR 12.31 - Plant pests.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Plant pests. 12.31 Section 12.31 Customs Duties U... SPECIAL CLASSES OF MERCHANDISE Wild Animals, Birds, and Insects § 12.31 Plant pests. The importation in a... Agriculture, Animal and Plant Health Inspection Service, Plant Protection and Quarantine Programs of that...

19 CFR 12.31 - Plant pests.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Plant pests. 12.31 Section 12.31 Customs Duties U... SPECIAL CLASSES OF MERCHANDISE Wild Animals, Birds, and Insects § 12.31 Plant pests. The importation in a... Agriculture, Animal and Plant Health Inspection Service, Plant Protection and Quarantine Programs of that...

Stabilization and Solidification of Nitric Acid Effluent Waste at Y-12

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, Dileep; Lorenzo-Martin, Cinta

Consolidated Nuclear Security, LLC (CNS) at the Y-12 plant is investigating approaches for the treatment (stabilization and solidification) of a nitric acid waste effluent that contains uranium. Because the pH of the waste stream is 1-2, it is a difficult waste stream to treat and stabilize by a standard cement-based process. Alternative waste forms are being considered. In this regard, Ceramicrete technology, developed at Argonne National Laboratory, is being explored as an option to solidify and stabilize the nitric acid effluent wastes.

Report on the biological monitoring program for Bear Creek at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee, 1989-1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hinzman, R.L.; Beauchamp, J.J.; Cada, G.F.

1996-04-01

The Bear Creek Valley watershed drains the area surrounding several closed Oak Ridge Y-12 Plant waste disposal facilities. Past waste disposal practices in the Bear Creek Valley resulted in the contamination of Bear Creek and consequent ecological damage. Ecological monitoring by the Biological Monitoring and Abatement Program (BMAP) was initiated in the Bear Creek watershed in May 1984 and continues at present. Studies conducted during the first year provided a detailed characterization of the benthic invertebrate and fish communities in Bear Creek. The initial characterization was followed by a biological monitoring phase in which studies were conducted at reduced intensities.

Safety analysis report for packaging, Oak Ridge Y-12 Plant, model DC-1 package with HEU oxide contents. Change pages for Rev.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This Safety Analysis Report for Packaging for the Oak Ridge Y-12 Plant for the Model DC-1 package with highly enriched uranium (HEU) oxide contents has been prepared in accordance with governing regulations form the Nuclear Regulatory Commission and the Department of Transportation and orders from the Department of energy. The fundamental safety requirements addressed by these regulations and orders pertain to the containment of radioactive material, radiation shielding, and nuclear subcriticality. This report demonstrates how these requirements are met.

Building dismantlement and site remediation at the Apollo Fuel Plant: When is technology the answer?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walton, L.

1995-01-01

The Apollo fuel plant was located in Pennsylvania on a site known to have been used continuously for stell production from before the Civil War until after World War II. Then the site became a nuclear fuel chemical processing plants. Finally it was used to convert uranium hexafluoride to various oxide fuel forms. After the fuel manufacturing operations were teminated, the processing equipment was partially decontaminated, removed, packaged and shipped to a licensed low-level radioactive waste burial site. The work was completed in 1984. In 1990 a detailed site characterization was initiated to establishe the extent of contamination and tomore » plan the building dismantlement and soil remediation efforts. This article discusses the site characterization and remedial action at the site in the following subsections: characterization; criticality control; mobile containment; soil washing; in-process measurements; and the final outcome of the project.« less

Remediating MGP brownfields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, B.R.

Before natural gas pipelines became widespread in this country, gas fuel was produced locally in more than 5,000 manufactured gas plants (MGPs). The toxic wastes from these processes often were disposed onsite and have since seeped into the surrounding soil and groundwater. Although the MGPs--commonly called gas plants, gas-works or town gas plants--have closed and most have been demolished, they have left a legacy of environmental contamination. At many MGP sites, underground storage tanks were constructed of wood or brick, with process piping and equipment which frequently leaked. Waste materials often were disposed onsite. Releases of coal tars, oils andmore » condensates produced within the plants contributed to a wide range of contamination from polycyclic aromatic hydrocarbons, phenols, benzene and cyanide. Remediation of selected MGP sites has been sporadic. Unless the site has been identified as a Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) Superfund site, the regulatory initiative to remediate often remains with the state in which the MGP is located. A number of factors are working to change that picture and to create a renewed interest in MGP site remediation. The recent Brownfield Initiative by the US Environmental Protection Agency (EPA) is such an example.« less

Remediation and reclamation of soils heavily contaminated with toxic metals as a substrate for greening with ornamental plants and grasses.

PubMed

Jelusic, Masa; Lestan, Domen

2015-11-01

Soils highly contaminated with toxic metals are currently treated as waste despite their potential inherent fertility. We applied EDTA washing technology featuring chelant and process water recovery for remediation of soil with 4037, 2527, and 26 mg kg(-1) of Pb, Zn and Cd, respectively in a pilot scale. A high EDTA dose (120 mmol kg(-1) of soil) removed 70%, 15%, and 58% of Pb, Zn, and Cd, respectively, and reduced human oral bioaccessibility of Pb below the limit of quantification and that of Zn and Cd 3.4 and 3.2 times. In a lysimeters experiment, the contaminated and remediated soils were laid into two garden beds (4×1×0.15 m) equipped with lysimeters, and subjected to cultivation of ornamental plants: Impatiens walleriana, Tagetes erecta, Pelargonium×peltatum, and Verbena×hybrida and grasses: Dactylis glomerata, Lolium multiflorum, and Festuca pratensis. Plants grown on remediated soil demonstrated the same or greater biomass yield and reduced the uptake of Pb, Zn and Cd up to 10, 2.5 and 9.5 times, respectively, compared to plants cultivated on the original soil. The results suggest that EDTA remediation produced soil suitable for greening. Copyright © 2014 Elsevier Ltd. All rights reserved.

Remedial investigation/feasibility study badger army ammunition plant Baraboo, Wisconsin. Volume 2. Feasibility study report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-08-01

This Feasibility Study (FS) report for the Badger Army Ammunition Plant (BAAP) in Baraboo, Wisconsin, was prepared by ABB Environmental Services, Inc. (ABB-ES) as a component of Task Order 1 of Contract DAAAl5-91-D-OOO8 with the U.S. Army Environmental Center (USAEC). This report uses the results presented in the Final Remedial Investigation (RI) report (ABB-ES, 1993a) to develop and screen alternatives for remediation of contaminated media at BAAP. The purpose of this FS report is to develop, screen, and evaluate site-specific remedial alternatives to mitigate the impact of site-derived chemicals and ultimately provide protection of human health and the environment. Preferredmore » alternatives for each site are included in this report. Based on previous environmental studies at BAAP, 11 potential hazardous waste sites were ranked according to potential contributions of hazardous chemicals to the environment. These sites were designated as Waste Management Areas because some of the sites contain multiple Solid Waste Management Units (SWMUs). The sites selected to undergo facility assessment and corrective actions are: the Propellant Burning Ground (including Landfill), Deterrent Burning Ground, existing Landfill, Settling Ponds and Spoils Disposal Area, Rocket Paste Area, Oleum Plant and Oleum Plant Pond, Nitroglycerine Pond, old Acid Area, new Acid Area, and Ballistics Pond. The USAEC added an 11th site, the Old Fuel Oil Tank, to the list in October 1989 after discovery of fuel-contaminated soils during excavation of a water line in the vicinity of the old fuel oil tank foundation.« less

Remedial investigation/feasibility study badger army ammunition plant Baraboo, Wisconsin. Volume 1. Feasibility study report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-08-01

This Feasibility Study (FS) report for the Badger Army Ammunition Plant (BAAP) in Baraboo, Wisconsin, was prepared by ABB Environmental Services, Inc. (ABB-ES) as a component of Task Order 1 of Contract DAAAl5-91-D-OOO8 with the U.S. Army Environmental Center (USAEC). This report uses the results presented in the Final Remedial Investigation (RI) report (ABB-ES, 1993a) to develop and screen alternatives for remediation of contaminated media at BAAP. The purpose of this FS report is to develop, screen, and evaluate site-specific remedial alternatives to mitigate the impact of site-derived chemicals and ultimately provide protection of human health and the environment. Preferredmore » alternatives for each site are included in this report. Based on previous environmental studies at BAAP, 11 potential hazardous waste sites were ranked according to potential contributions of hazardous chemicals to the environment. These sites were designated as Waste Management Areas because some of the sites contain multiple Solid Waste Management Units (SWMUs). The sites selected to undergo facility assessment and corrective actions are: the Propellant Burning Ground (including Landfill), Deterrent Burning Ground, existing Landfill, Settling Ponds and Spoils Disposal Area, Rocket Paste Area, Oleum Plant and Oleum Plant Pond, Nitroglycerine Pond, old Acid Area, new Acid Area, and Ballistics Pond. The USAEC added an 11th site, the Old Fuel Oil Tank, to the list in October 1989 after discovery of fuel-contaminated soils during excavation of a water line in the vicinity of the old fuel oil tank foundation.« less

Proposed plan for remedial action for the Groundwater Operable Unit at the Chemical Plant Area of the Weldon Spring Site, Weldon Spring, Missouri

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1999-08-10

This Proposed Plan addresses the remediation of groundwater contamination at the chemical plant area of the Weldon Spring site in Weldon Spring, Missouri. The site is located approximately 48 km (30 mi) west of St. Louis in St. Charles County . Remedial activities at the site will be conducted in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). The U.S. Department of Energy (DOE), in conjunction with the U.S. Department of the Army (DA), conducted a joint remedial investigation/feasibility study (RI/FS) to allow for a comprehensive evaluation of groundwater conditions at the Weldon Spring chemical plant areamore » and the Weldon Spring ordnance works area, which is an Army site adjacent to the chemical plant area. Consistent with DOE policy, National Environmental Policy Act (NEPA) values have been incorporated into the CERCLA process. That is, the analysis conducted and presented in the RVFS reports included an evaluation of environmental impacts that is comparable to that performed under NEPA. This Proposed Plan summarizes information about chemical plant area groundwater that is presented in the following documents: (1) The Remedial Investigation (RI), which presents information on the nature and extent of contamination; (2) The Baseline Risk Assessment (BRA), which evaluates impacts to human health and the environment that could occur if no cleanup action of the groundwater were taken (DOE and DA 1997a); and (3) The Feasibility Study (FS) and the Supplemental FS, which develop and evaluate remedial action alternatives for groundwater remediation.« less

Plant Sources of Chinese Herbal Remedies: Effects on Pratylenchus vulnus and Meloidogyne javanica

PubMed Central

Ferris, H.; Zheng, L.

1999-01-01

More than 500 plant species, used alone or in combination, are documented in Chinese traditional medicine to have activity against helminth and micro-invertebrate pests of humans. We subjected 153 candidate medicines or their plant sources to multilevel screening for effectiveness against plant-parasitic nematodes. For extracts effective in preliminary screens, we determined time-course and concentration-response relationships. Seventy-three of the aqueous extracts of medicines or their plant sources killed either Meloidogyne javanica juveniles or Pratylenchus vulnus (mixed stages), or both, within a 24-hour exposure period. Of 64 remedies reported as antihelminthics, 36 were effective; of 21 classi- fied as purgatives, 13 killed the nematodes; of 29 indicated as generally effective against pests, 13 killed the nematodes. Sources of extracts effective against one or both species of plant-parasitic nematodes are either the whole plant or vegetative, storage or reproductive components of the plants. Effective plants include both annuals and perennials, range from grasses and herbs to woody trees, and represent 46 plant families. PMID:19270895

Examining the Links between Grade 12 Mathematics and Remedial Courses in Nevada Public Colleges and Universities. Issues & Answers. REL 2008-No. 058

ERIC Educational Resources Information Center

Fong, Anthony B.; Huang, Min; Goel, Aditi M.

2008-01-01

This study examines the links between Nevada's grade 12 mathematics courses and remedial mathematics courses in Nevada's public colleges and universities. It analyzes remediation rates by students' highest grade 12 mathematics course level and mathematics grade point average and by various student and school characteristics. The study was guided…

Lithium toxicity in plants: Reasons, mechanisms and remediation possibilities - A review.

PubMed

Shahzad, Babar; Tanveer, Mohsin; Hassan, Waseem; Shah, Adnan Noor; Anjum, Shakeel Ahmad; Cheema, Sardar Alam; Ali, Iftikhar

2016-10-01

Lithium (Li) is a naturally occurring element; however, it is one of the non-essential metals for life. Lithium is becoming a serious matter of discussion for the people who do research on trace metals and environmental toxicity in plants. Due to limited information available regarding its mobility from soil to plants, the adverse effects of Li toxicity to plants are still unclear. This article briefly discusses issues around Li, its role and its essentiality in plants and research directions that may assist in inter-disciplinary studies to evaluate the importance of Li's toxicity. Further, potential remediation approaches will also be highlighted in this review. Briefly, Li influenced the growth of plants in both stimulation and reduction ways, depending on the concentration of Li in growth medium. On the negative side, Li reduces the plant growth by interrupting numerous physiological processes and altering metabolism in plant. The contamination of soil by Li is becoming a serious problem, which might be a threat for crop production in the near future. Additionally, lack of considerable information about the tolerance mechanisms of plants further intensifies the situation. Therefore, future research should emphasize in finding prominent and approachable solutions to minimize the entry of Li from its sources (especially from Li batteries) into the soil and food chain. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Effect of eco-remediation using planted floating bed system on nutrients and heavy metals in urban river water and sediment: a field study in China.

PubMed

Ning, Daliang; Huang, Yong; Pan, Ruisong; Wang, Fayuan; Wang, Hui

2014-07-01

To investigate the effect of the eco-remediation on nutrients and heavy metals in river water and sediment, a field study was carried out in a site of a 2-year eco-remediation mainly using planted floating bed system in an urban river in China. Before remediation, the tested properties of water and sediment in the will-be remediated area were not different from the control area, except higher concentrations of chemical oxygen demand (COD) and total nitrogen (TN) in the river water. After remediation, the remediation area showed effective removal of in-stream nutrients and elevation of dissolved oxygen and transparency. Compared to the control area, the remediation area had higher concentration of nitrate and lower concentrations of COD, ammonium, Mn and hexavalent Cr in the river water after a 2-year remediation. The remediation area also showed higher concentrations of organic carbon, TN, nitrate, sulfate, Fe, Cu, Pb and Zn in the sediment than in the control area. Accordingly, special attention should be paid to the ecological risk of heavy metals in sediments and plants in river eco-remediation projects especially in rivers polluted by heavy metals, although the metals were lower than the level of considerable ecological risk in this study. Copyright © 2014 Elsevier B.V. All rights reserved.

Identification of the mosquito biting deterrent constituents from the Indian folk remedy plant Jatropha curcas

USDA-ARS?s Scientific Manuscript database

An investigation of the Indian folk remedy plant, Jatropha curcas, was performed to specifically identify the constituents responsible for the mosquito biting deterrent activity of the oil as a whole. Jatropha curcas seed oil is burned in oil lamps in India and part of Africa to repel biting insect...

Construction quality assurance report for the Y-12 Construction/Demolition Landfill VII (CDL VII), Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burton, P.M.

This Construction Quality Assurance (CQA) Report provides documentation that Bid Option 2 of the Y-12 Plant Construction Demolition Landfill 7 (CDL-7) was constructed in substantial compliance with the Tennessee Department of Environment and Conservation (TDEC) approved design, as indicated and specified in the permit drawings, approved changes, and specifications. CDL-7 is located in Anderson County on the south side of Chestnut Ridge, approximately 0.5 miles south of the Y-12 Plant in Oak Ridge, Tennessee. This report applies specifically to the limits of excavation for Area No. 1 portions of the perimeter maintenance road and drainage channel and Sedimentation Pond No.more » 3. A partial ``As-Built`` survey was performed and is included.« less

Remedial investigation/feasibility study badger army ammunition plant Baraboo, Wisconsin. Volume 3. Feasibility study report (Final)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-08-01

This Feasibility Study (FS) report for the Badger Army Ammunition Plant (BAAP) in Baraboo, Wisconsin, was prepared by ABB Environmental Services, Inc. (ABB-ES) as a component of Task Order 1 of Contract DAAAl5-91-D-OOO8 with the U.S. Army Environmental Center (USAEC). This report uses the results presented in the Final Remedial Investigation (RI) report (ABB-ES, 1993a) to develop and screen alternatives for remediation of contaminated media at BAAP. The purpose of this FS report is to develop, screen, and evaluate site-specific remedial alternatives to mitigate the impact of site-derived chemicals and ultimately provide protection of human health and the environment. Preferredmore » alternatives for each site are included in this report. Based on previous environmental studies at BAAP, 11 potential hazardous waste sites were ranked according to potential contributions of hazardous chemicals to the environment. These sites were designated as Waste Management Areas because some of the sites contain multiple Solid Waste Management Units (SWMUs). The sites selected to undergo facility assessment and corrective actions are: the Propellant Burning Ground (including Landfill), Deterrent Burning Ground, existing Landfill, Settling Ponds and Spoils Disposal Area, Rocket Paste Area, Oleum Plant and Oleum Plant Pond, Nitroglycerine Pond, old Acid Area, new Acid Area, and Ballistics Pond. The USAEC added an 11th site, the Old Fuel Oil Tank, to the list in October 1989 after discovery of fuel-contaminated soils during excavation of a water line in the vicinity of the old fuel oil tank foundation.« less

Remediation aspect of microbial changes of plant rhizosphere in mercury contaminated soil.

PubMed

Sas-Nowosielska, Aleksandra; Galimska-Stypa, Regina; Kucharski, Rafał; Zielonka, Urszula; Małkowski, Eugeniusz; Gray, Laymon

2008-02-01

Phytoremediation, an approach that uses plants to remediate contaminated soil through degradation, stabilization or accumulation, may provide an efficient solution to some mercury contamination problems. This paper presents growth chamber experiments that tested the ability of plant species to stabilize mercury in soil. Several indigenous herbaceous species and Salix viminalis were grown in soil collected from a mercury-contaminated site in southern Poland. The uptake and distribution of mercury by these plants were investigated, and the growth and vitality of the plants through a part of one vegetative cycle were assessed. The highest concentrations of mercury were found at the roots, but translocation to the aerial part also occurred. Most of the plant species tested displayed good growth on mercury contaminated soil and sustained a rich microbial population in the rhizosphere. The microbial populations of root-free soil and rhizosphere soil from all species were also examined. An inverse correlation between the number of sulfur amino acid decomposing bacteria and root mercury content was observed. These results indicate the potential for using some species of plants to treat mercury contaminated soil through stabilization rather than extraction. The present investigation proposes a practical cost-effective temporary solution for phytostabilization of soil with moderate mercury contamination as well as the basis for plant selection.

19 CFR 12.31 - Plant pests.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Plant pests. 12.31 Section 12.31 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Wild Animals, Birds, and Insects § 12.31 Plant pests. The importation in a...

19 CFR 12.31 - Plant pests.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Plant pests. 12.31 Section 12.31 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Wild Animals, Birds, and Insects § 12.31 Plant pests. The importation in a...

Ethnobotanical survey of medicinal plants used as anthelmintic remedies in Gabon.

PubMed

Bajin Ba Ndob, Idensi; Mengome, Line Edwige; Bourobou Bourobou, Henri-Paul; Lossangoye Banfora, Yvon; Bivigou, Francis

2016-09-15

In this article, we report on an ethnobotanical survey realized at the Peyrie market in Libreville on Gabonese medicinal plants used to treat helminthiasis. While several alerts about cases of resistance to conventional anthelmintic treatments are causing to fear a public and animal health issue, the search for new sources of active compounds becomes an urgent issue. In Gabon like in many developing countries, people regularly turn to traditional medicine in case of physical ailments and/or spiritual healing therapies. To determine which medicinal plants are traditionally used by the populations of Libreville to fight against nematodes, medicinal plant traders were interviewed with standardized questionnaires. The surveys were conducted in the main market of Libreville. Ethnobotanical data such as frequency and percentage of families, species, administrations pathways, modes of preparations and parts of plants used were analyzed and summarized. Thirty-four (34) traders were interviewed belonging to five (5) different ethnic groups. Twenty-four 24 plants used to treat intestinal, cutaneous and ocular helminthiasis were listed. The healers mainly turned towards to ligneous species. The parts of the plant used are mostly leaves and trunk bark. Most of the traditional remedies are prepared directly in water and four (4) principal routes were used for administration namely, oral, rectal, ocular and dermal. This study allowed us to list anthelmintic species which will be subjected to a series of chemical and pharmacological assays. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Proposed plan for final remedial action for the groundwater operable unit at the chemical plant area of the Weldon Spring Site, Weldon Spring, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2003-08-06

This Proposed Plan (PP) presents the preferred alternative for addressing contaminated groundwater and springs at the Chemical Plant area of the Weldon Spring site, in Weldon Spring, Missouri. The site is located about 30 mi west of St. Louis, in St. Charles County (Figure 1). This proposed action constitutes the final remedial action for the Weldon Spring site. The residual contamination in groundwater and springs at the Chemical Plant area is the only remaining contamination that needs to be addressed for the site. All other contamination has been addressed by previous remedial actions. After this remedial action is implemented, long-termmore » surveillance and maintenance activities will maintain the effectiveness of all remedial actions conducted at the Weldon Spring site, including this final remedial action for groundwater and springs that is being proposed in this plan. DOE complies with the requirements of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) in conducting remedial activities at the site. National Environmental Policy Act (NEPA) values have been incorporated into the CERCLA process; that is, the analysis conducted and presented in the remedial investigation/feasibility study (RI/FS) reports included an evaluation of environmental impacts that is comparable to that performed under NEPA. This PP is required under CERCLA to (1) notify the public and present a brief analysis of the remedial action alternatives, (2) identify and present the rationale for the preferred remedial action alternative identified in the PP, (3) summarize key information from the RI/FS evaluations, including the Baseline Risk Assessment (BRA), and (4) inform the public of its role in the remedy selection process and give the public the opportunity to participate in the process. Remediation activities at the Weldon Spring site have been coordinated with the U.S. Environmental Protection Agency (EPA) and the Missouri Department of Natural

Remediation of radiocesium-contaminated liquid waste, soil, and ash: a mini review since the Fukushima Daiichi Nuclear Power Plant accident.

PubMed

Ding, Dahu; Zhang, Zhenya; Lei, Zhongfang; Yang, Yingnan; Cai, Tianming

2016-02-01

The radiation contamination after the Fukushima Daiichi Nuclear Power Plant accident attracts considerable concern all over the world. Many countries, areas, and oceans are greatly affected by the emergency situation other than Japan. An effective remediation strategy is in a highly urgent demand. Though plenty of works have been carried out, progressive achievements have not yet been well summarized. Here, we review the recent advances on the remediation of radiocesium-contaminated liquid waste, soil, and ash. The overview of the radiation contamination is firstly given. Afterwards, the current remediation strategies are critically reviewed in terms of the environmental medium. Special attentions are paid on the adsorption/ion exchange and electrically switched ion exchange methods. Finally, the present review outlines the possible works to do for the large-scale application of the novel remediation strategies.

Permeability and storage ability of inorganic X12Y12 fullerenes for lithium atom and ion

NASA Astrophysics Data System (ADS)

Munsif, Sajida; Ayub, Khurshid

2018-04-01

In the current study, permeability and storage ability (exohedral and endohedral) of inorganic fullerenes X12Y12 (X = B, Al and Y = N, P) for lithium atom/ion (Li/Li+) is studied theoretically at M05-2X method. The translation of Li/Li+ through Al12P12 nano-cages is not only a kinetically feasible process but also has very high separation ratio in the favor of lithium atom over lithium ion. Adsorption/encapsulation energies of alkali metal on/in nano-cages show strong correlation with the size of the nano-cage. The percent changes in H-L gap for Li+-X12Y12 are about 1-25%, whereas the corresponding changes for Li-X12Y12 are 30-72%.

Evaluation and determination of soil remediation schemes using a modified AHP model and its application in a contaminated coking plant.

PubMed

Li, Xingang; Li, Jia; Sui, Hong; He, Lin; Cao, Xingtao; Li, Yonghong

2018-07-05

Soil remediation has been considered as one of the most difficult pollution treatment tasks due to its high complexity in contaminants, geological conditions, usage, urgency, etc. The diversity in remediation technologies further makes quick selection of suitable remediation schemes much tougher even the site investigation has been done. Herein, a sustainable decision support hierarchical model has been developed to select, evaluate and determine preferred soil remediation schemes comprehensively based on modified analytic hierarchy process (MAHP). This MAHP method combines competence model and the Grubbs criteria with the conventional AHP. It not only considers the competence differences among experts in group decision, but also adjusts the big deviation caused by different experts' preference through sample analysis. This conversion allows the final remediation decision more reasonable. In this model, different evaluation criteria, including economic effect, environmental effect and technological effect, are employed to evaluate the integrated performance of remediation schemes followed by a strict computation using above MAHP. To confirm the feasibility of this developed model, it has been tested by a benzene workshop contaminated site in Beijing coking plant. Beyond soil remediation, this MAHP model would also be applied in other fields referring to multi-criteria group decision making. Copyright © 2018 Elsevier B.V. All rights reserved.

USE OF PLANT AND EARTHWORM BIOASSYS TO EVALUATE REMEDIATION OF SOIL FROM A SITE CONTAMINATED WITH POLYCHLORINATED BIPHENYLS

EPA Science Inventory

Soil from a site heavily contaminated with polychlorinated biphenyls (PCBs) was treated with a pilot-scale, solvent extraction tehnology. Bioassays in earthworms and plants were used to examine the efficacy of the remediation process for reducing the toxicity of the soil. The ear...

USE OF PLANT AND EARTHWORM BIOASSAYS TO EVALUATE REMEDIATION OF SOIL FROM A SITE CONTAMINATED WITH POLYCHLORINATED BIPHENYLS

EPA Science Inventory

Soil from a site heavily contaminated with polychlorinated biphenyls (PCBs) was treated with a pilot-scale, solvent extraction technology. Bioassays in earthworms and plants were used to examine the efficacy of the remediation process for reducing the toxicity of the soil. The ...

Y-12 Groundwater Protection Program CY2012 Triennial Report Of The Monitoring Well Inspection And Maintenance Program Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2013-09-01

This document is the triennial report for the Well Inspection and Maintenance Program of the Y- 12 Groundwater Protection Program (GWPP), at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12). This report formally documents well inspections completed by the GWPP on active and inactive wells at Y-12 during calendar years (CY) 2010 through 2012. In addition, this report also documents well inspections performed under the Y-12 Water Resources Restoration Program, which is administered by URS|CH2M Oak Ridge (UCOR). This report documents well maintenance activities completed since the last triennial inspection event (CY 2009); and provides summary tablesmore » of well inspections and well maintenance activities during the reference time period.« less

Friends or foes? Monetized Life Cycle Assessment and Cost-Benefit Analysis of the site remediation of a former gas plant.

PubMed

Huysegoms, Lies; Rousseau, Sandra; Cappuyns, Valérie

2018-04-01

Site contamination is a global concern because of the potential risks for human health and ecosystem quality. Every contaminated site has its own specific characteristics and the increased availability and efficiency of remediation techniques makes the choice of remediation alternative increasingly complicated. In this paper an attributional Life Cycle Assessment (LCA) of the secondary environmental impacts of a site remediation is performed and its results are monetized using two different monetization techniques, namely Stepwise 2006 and Ecovalue 08. Secondly, we perform a social Cost-Benefit Analysis (CBA) on the same case study using the same data sources. The case study used in this paper entails the soil and groundwater remediation of a tar, poly-aromatic hydrocarbons (PAH) and cyanide contamination of a school ground by a former gas plant. The remediation alternative chosen in this case study is excavation with off-site thermal treatment of the contaminated soil. The outcome of the social CBA, stating that the remediation project is socially beneficial in the long term, is critically compared to the outcome of the different LCA monetization methods. This comparison indicates that monetized LCA is a good complement to social CBA when it comes to the assessment of secondary environmental impacts. Combining the two methods provides decision makers with a more extensive and detailed assessment of the soil remediation project. Copyright © 2017 Elsevier B.V. All rights reserved.

Remedial investigation work plan for Bear Creek Valley Operable Unit 2 (Rust Spoil Area, SY-200 Yard, Spoil Area 1) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Environmental Restoration Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-05-01

The enactment of the Resource Conservation and Recovery Act (RCRA) in 1976 and the Hazardous and Solid Waste Amendments (HSWA) to RCRA in 1984 created management requirements for hazardous waste facilities. The facilities within the Oak Ridge Reservation (ORR) were in the process of meeting the RCRA requirements when ORR was placed on the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) on November 21, 1989. Under RCRA, the actions typically follow the RCRA Facility Assessment (RFA)/RCRA Facility Investigation (RFI)/Corrective Measures Study (CMS)/Corrective Measures implementation process. Under CERCLA the actions follow the PA/SI/Remedial Investigation (RI)/Feasibility Studymore » (FS)/Remedial Design/Remedial Action process. The development of this document will incorporate requirements under both RCRA and CERCLA into an RI work plan for the characterization of Bear Creek Valley (BCV) Operable Unit (OU) 2.« less

50 CFR 17.12 - Endangered and threatened plants.

Code of Federal Regulations, 2013 CFR

2013-10-01

... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Lists § 17.12 Endangered and threatened plants. (h) * * * Species Scientific name Common name Historic range Family Status When listed... 50 Wildlife and Fisheries 2 2013-10-01 2013-10-01 false Endangered and threatened plants. 17.12...

Combination of aquatic species and safeners improves the remediation of copper polluted water.

PubMed

Panfili, Ivan; Bartucca, Maria Luce; Ballerini, Eleonora; Del Buono, Daniele

2017-12-01

In the last decades, many anthropogenic activities have resulted in heavy metal contamination of freshwaters and surrounding environments. This poses serious threats to human health. Phytoremediation is a cost-effective technology which is useful for remediating polluted soils and water. Recently, the use of aquatic free-floating plants has been proposed to remediate polluted water. In this context, a study on the capacity of two aquatic plants, Lemna minor (duckweed) and Salvinia auriculata (salvinia), to remediate Cu +2 (Cu) polluted water was carried out. Initially, the species were exposed to different copper concentrations (1, 5, 10, 20 and 50μmolL -1 ) in order to assess Cu +2 toxicity to the plants. In addition, plants were treated with two safeners (benoxacor and dichlormid), with the aim of pointing out any safening effect of these compounds on the aquatic species. Toxicity tests showed that safened plants had a greater Cu resistance, especially at the higher Cu doses. Finally, unsafened and safened plants were tested in the decontamination of water polluted by copper (1.2mgL -1 ). In general, duckweed removed higher amounts of Cu from polluted water than salvinia, and, surprisingly, for both the species the safeners significantly increased the plants' capacity to remove the metal from the polluted waters. Lastly, an HPLC-based method was developed and standardized to monitor the residual amounts of the two safeners in the water. While dichlormid was completely absorbed by duckweed within few days after the treatments, some residual amounts of both safeners were found in salvinia vegetated water after two weeks. In conclusion, the results of this research show that the use of aquatic species in combination with safeners is an attractive and reliable tool to make plants more effective in phytoremediation of water polluted with metals (or other toxic compounds). Copyright © 2017 Elsevier B.V. All rights reserved.

Microemulsion-enhanced remediation of soils contaminated with organochlorine pesticides.

PubMed

Zhang, Yanlin; Wong, Jonathan W C; Zhao, Zhenyong; Selvam, Ammaiyappan

2011-12-01

Soil contaminated by organic pollutants, especially chlorinated aromatic compounds such as DDT (1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane), is an environmental concern because of the strong sorption of organochlorine pesticide onto the soil matrix and persistence in the environment. The remediation of organochlorine pesticide contaminated soils through microemulsion is an innovative technology to expedite this process. The remediation efficiency was evaluated by batch experiments through studying the desorption of DDT and hexachlorocyclohexane (y-HCH) and sorption of microemulsion composed of Triton X-100, 1-pentanol and linseed oil in the soil-surfactant-water suspension system. The reduction of desorption efficiency caused by the sorption loss of microemulsion components onto the soil could be corrected by the appropriate adjustment of C/S (Cosurfactant/Surfactant) and O/S (Oil/Surfactant) ratio. The C/S and O/S ratios of 1:2 and 3:20 were suitable to desorb DDT and gamma-HCH from the studied soils because of the lower sorption of Triton X-100 onto the soil. Inorganic salts added in microemulsion increased the pesticides desorption efficiency of pesticides and calcium chloride has a stronger ability to enhance the desorption of DDT than sodium chloride. From the remediation perspective, the balance of surfactant or cosurfactant sorbed to soil and desorption efficiency should be taken into consideration to enhance the remediation of soils contaminated by organochlorine pesticides.

The phyto-remediation of radioactively contaminated land - a feasible approach or just bananas?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nesbitt, Victoria A

2013-07-01

Soil is an essential component of all terrestrial ecosystems and is under increasing threat from human activity. Techniques available for removing radioactive contamination from soil and aquatic substrates are limited and often costly to implement; particularly over large areas. Frequently, bulk soil removal, with its attendant consequences, is a significant component of the majority of contamination incidents. Alternative techniques capable of removing contamination or exposure pathways without damaging or removing the soil are therefore of significant interest. An increasing number of old nuclear facilities are entering 'care and maintenance', with significant ground contamination issues. Phyto-remediation - the use of plants'more » natural metabolic processes to remediate contaminated sites is one possible solution. Its key mechanisms include phyto-extraction and phyto-stabilisation. These are analogues of existing remedial techniques. Further, phyto-remediation can improve soil quality and stability and restore functionality. Information on the application of phyto-remediation in the nuclear industry is widely distributed over an extended period of time and sources. It is therefore difficult to quickly and effectively identify which plants would be most suitable for phyto-remediation on a site by site basis. In response, a phyto-remediation tool has been developed to address this issue. Existing research and case studies were reviewed to understand the mechanisms of phyto-remediation, its effectiveness and the benefits and limitations of implementation. The potential for cost recovery from a phyto-remediation system is also briefly considered. An overview of this information is provided here. From this data, a set of matrices was developed to guide potential users through the plant selection process. The matrices take the user through a preliminary screening process to determine whether the contamination present at their site is amenable to phyto-remediation

Dementia Etiologies and Remedies in Traditional Persian Medicine; A Review of Medicinal Plants and Phytochemistry.

PubMed

Shirbeigi, Laila; Dalfardi, Behnam; Abolhassanzadeh, Zohreh; Nejatbakhsh, Fatemeh

2018-01-01

Dementia is a chronic neurodegenerative disease causing progressive and gradual impairment of different brain's cognitive functions. The prevalence of dementia is about 3 to 7% in different parts of the world. The aim of this study was to determine the etiologies of dementia according to the Traditional Persian Medicine scientists' viewpoint and introduce their recommended herbal remedies for this disease. The authors explored six main Traditional Persian Medicine textbooks for the disease of dementia, its etiologies and related recommended herbal treatments. Two main keywords of "Lisarghes" and" Nesyan" were searched for this purpose. Medical databases, including PubMed, Scopus, Google Scholar, and Science Direct were searched for related articles published between 1966 and 2016 to review the pharmacological components and active ingredients of suggested herbal medicines. According to the Traditional Persian Medicine, dementia is resulted from brain dystemperament, a condition caused by cold and moist or cold and dry tempers. To treat this disease, Traditional Persian scientists recommended various herbal remedies. Current studies have demonstrated that some of these medicinal plants have beneficial effects for the aforementioned disease, including acetyl cholinesterase inhibitory function, neuroprotective effects, and memory enhancing role. The Traditional Persian Medicine literature suggested different herbal remedies for treating dementia. Modern studies support the usefulness of some of these medicines. However, the effect of a large number of these remedies has remained unexamined, a matter which needs to be investigated in future researches. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Sampling results, DNAPL monitoring well GW-729, Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Drier, R.B.; Caldanaro, A.J.

1996-12-01

This document, Sampling Results, DNAPL Monitoring Well G W-729, Third Quarter FY 1995 through Third Quarter FY 1996, was performed under Work Breakdown Structure 1.4.12.1.1.02 (Activity Data Sheet 2312, `Bear Creek Valley`). This document provides the Environmental Restoration Program with groundwater concentrations for nonradionuclides in the vicinity of the Y-12 Burial Grounds. These data can be used to determine reference concentrations for intermediate and deep groundwater systems.

Molecular mechanisms of platelet P2Y(12) receptor regulation.

PubMed

Cunningham, Margaret R; Nisar, Shaista P; Mundell, Stuart J

2013-02-01

Platelets are critical for haemostasis, however inappropriate activation can lead to the development of arterial thrombosis, which can result in heart attack and stroke. ADP is a key platelet agonist that exerts its actions via stimulation of two surface GPCRs (G-protein-coupled receptors), P2Y(1) and P2Y(12). Similar to most GPCRs, P2Y receptor activity is tightly regulated by a number of complex mechanisms including receptor desensitization, internalization and recycling. In the present article, we review the molecular mechanisms that underlie P2Y(1) and P2Y(12) receptor regulation, with particular emphasis on the structural motifs within the P2Y(12) receptor, which are required to maintain regulatory protein interaction. The implications of these findings for platelet responsiveness are also discussed.

Developing microbe–plant interactions for applications in plant‐growth promotion and disease control, production of useful compounds, remediation and carbon sequestration

PubMed Central

Wu, Cindy H.; Bernard, Stéphanie M.; Andersen, Gary L.; Chen, Wilfred

2009-01-01

Summary Interactions between plants and microbes are an integral part of our terrestrial ecosystem. Microbe–plant interactions are being applied in many areas. In this review, we present recent reports of applications in the areas of plant‐growth promotion, biocontrol, bioactive compound and biomaterial production, remediation and carbon sequestration. Challenges, limitations and future outlook for each field are discussed. PMID:21255275

Functional remediation components: A conceptual method of evaluating the effects of remediation on risks to ecological receptors.

PubMed

Burger, Joanna; Gochfeld, Michael; Bunn, Amoret; Downs, Janelle; Jeitner, Christian; Pittfield, Taryn; Salisbury, Jennifer

2016-01-01

Governmental agencies, regulators, health professionals, tribal leaders, and the public are faced with understanding and evaluating the effects of cleanup activities on species, populations, and ecosystems. While engineers and managers understand the processes involved in different remediation types such as capping, pump and treat, and natural attenuation, there is often a disconnect between (1) how ecologists view the influence of different types of remediation, (2) how the public perceives them, and (3) how engineers understand them. The overall goal of the present investigation was to define the components of remediation types (= functional remediation). Objectives were to (1) define and describe functional components of remediation, regardless of the remediation type, (2) provide examples of each functional remediation component, and (3) explore potential effects of functional remediation components in the post-cleanup phase that may involve continued monitoring and assessment. Functional remediation components include types, numbers, and intensity of people, trucks, heavy equipment, pipes, and drill holes, among others. Several components may be involved in each remediation type, and each results in ecological effects, ranging from trampling of plants, to spreading invasive species, to disturbing rare species, and to creating fragmented habitats. In some cases remediation may exert a greater effect on ecological receptors than leaving the limited contamination in place. A goal of this conceptualization is to break down functional components of remediation such that managers, regulators, and the public might assess the effects of timing, extent, and duration of different remediation options on ecological systems.

Y-12 Integrated Materials Management System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alspaugh, D. H.; Hickerson, T. W.

2002-06-03

The Integrated Materials Management System, when fully implemented, will provide the Y-12 National Security Complex with advanced inventory information and analysis capabilities and enable effective assessment, forecasting and management of nuclear materials, critical non-nuclear materials, and certified supplies. These capabilities will facilitate future Y-12 stockpile management work, enhance interfaces to existing National Nuclear Security Administration (NNSA) corporate-level information systems, and enable interfaces to planned NNSA systems. In the current national nuclear defense environment where, for example, weapons testing is not permitted, material managers need better, faster, more complete information about material properties and characteristics. They now must manage non-special nuclearmore » material at the same high-level they have managed SNM, and information capabilities about both must be improved. The full automation and integration of business activities related to nuclear and non-nuclear materials that will be put into effect by the Integrated Materials Management System (IMMS) will significantly improve and streamline the process of providing vital information to Y-12 and NNSA managers. This overview looks at the kinds of information improvements targeted by the IMMS project, related issues, the proposed information architecture, and the progress to date in implementing the system.« less

Postconstruction report for the mercury tanks interim action at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voskuil, T.L.

1993-09-01

Three underground concrete settling tanks (tanks 2101-U, 2104-U, and 2100-U) at the Y-12 Plant on the Oak Ridge Reservation in Oak Ridge, Tennessee, contained contaminated sludges contributing mercury to the Upper East Fork Poplar Creek (UEFPC). These tanks were cleaned out as an interim action under the Comprehensive Environmental Response, Compensation, and Liability Act as part of the Reduction of Mercury in Plant Effluent subproject. Cleaning out these tanks prevented the sludge that had settled in the bottom from resuspending and carrying mercury into UEFPC. Tanks 2104-U and 2100-U were returned to service and will continue to receive effluent frommore » buildings 9201-4 and 9201-5. Tank 2101-U had been abandoned and its effluent redirected to Tank 2100-U during previous activities. This interim action permanently sealed Tank 2101-U from the storm sewer system. Upon removal of materials and completion of cleanup, inspections determined that the project`s cleanup criteria had been met. The structural integrity of the tanks was also inspected, and minor cracks identified in tanks 2101-U and 2104-U were repaired. This project is considered to have been completed successfully because it met its performance objectives as addressed in the Interim Record of Decision and the work plan: to remove the waste from the three storage tanks; to ensure that the tanks were cleaned to the levels specified; to return tanks 2100-U and 2104-U to service; to isolate Tank 2101-U permanently; and to manage the wastes in an appropriate fashion.« less

Site remediation techniques in India: a review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anomitra Banerjee; Miller Jothi

India is one of the developing countries operating site remediation techniques for the entire nuclear fuel cycle waste for the last three decades. In this paper we intend to provide an overview of remediation methods currently utilized at various hazardous waste sites in India, their advantages and disadvantages. Over the years the site remediation techniques have been well characterized and different processes for treatment, conditioning and disposal are being practiced. Remediation Methods categorized as biological, chemical or physical are summarized for contaminated soils and environmental waters. This paper covers the site remediation techniques implemented for treatment and conditioning of wastelandsmore » arising from the operation of nuclear power plant, research reactors and fuel reprocessing units. (authors)« less

Removing Remediation Requirements: Effectiveness of Intervention Programs

ERIC Educational Resources Information Center

Fine, Anne; Duggan, Mickle; Braddy, Linda

2009-01-01

Remediation of incoming college freshman students is a national concern because remediated students are at higher risk of failing to complete their degrees. Some Oklahoma higher education institutions are working to assist K-12 systems in finding ways to reduce the number of incoming college freshman students requiring remediation. This study…

Do patients with bipolar disorder and subsyndromal symptoms benefit from functional remediation? A 12-month follow-up study.

PubMed

Sanchez-Moreno, Jose; Bonnín, Caterina; González-Pinto, Ana; Amann, Benedikt L; Solé, Brisa; Balanzá-Martínez, Vicent; Arango, Celso; Jimenez, Esther; Tabarés-Seisdedos, Rafael; Garcia-Portilla, M Paz; Ibáñez, Angela; Crespo, Jose Manuel; Ayuso-Mateos, Jose Luis; Vieta, Eduard; Martinez-Aran, Anabel; Torrent, Carla

2017-04-01

We analyzed the efficacy of functional remediation, in a sample of patients with bipolar disorder who presented with subsyndromal symptoms. From a total sample of 239 patients with bipolar I and II disorder, according to DSM-IV-TR diagnostic criteria, entering a randomized clinical trial, those patients who presented with subsyndromal symptoms were selected based on a method already described by Berk and colleagues was applied. It consists of using the Clinical Global Impression-Bipolar version (CGI-BP) to establish the scores of the Hamilton Depression Rating Scale (HAM-D) and of the Young Mania Rating Scale (YMRS) that correspond with 1 in the CGI-BP. Functional outcome and mood symptoms were assessed at 6 and at 12-month follow-up. A total of 99 patients were selected for this post-hoc analysis, allocated as follows: functional remediation (n=33); psychoeducation (n=37) and treatment as usual (TAU,n=29). The repeated-measures analyses at 12-month follow-up revealed a significant group x time interaction in favour of the patients who received functional remediation when compared to psychoeducation and TAU (F=2.93; p=0.02) at improving psychosocial functioning. Finally, mood symptoms did not significantly change in any of the three groups at any time of follow-up, as shown by the non-significant group x time interaction effect in HAM-D scores (F=1.57; p=0.18) and YMRS scores (F=1.51; p=0.20). Bipolar patients with subsyndromal symptoms improve their functional outcome when exposed to functional remediation regardless of the persistence of mood symptomatology. Copyright © 2017 Elsevier B.V. and ECNP. All rights reserved.

Dense Nonaqueous Phase Liquids at Former Manufactured Gas Plants: Challenges to Modeling and Remediation

PubMed Central

Birak, P.S.; Miller, C.T.

2008-01-01

The remediation of dense non-aqueous phase liquids (DNAPLs) in porous media continues to be one of the most challenging problems facing environmental scientists and engineers. Of all the environmentally relevant DNAPLs, tars in the subsurface at former manufactured gas plants (FMGP’s) pose one of the biggest challenges due to their complex chemical composition and tendency to alter wettability. To further our understanding of these complex materials, we consulted historic documentation to evaluate the impact of gas manufacturing on the composition and physicochemical nature of the resulting tars. In the recent literature, most work to date has been focused in a relatively narrow portion of the expected range of tar materials, which has yielded a bias toward samples of relatively low viscosity and density. In this work, we consider the dissolution and movement of tars in the subsurface, models used to predict these phenomena, and approaches used for remediation. We also explore the open issues and detail important gaps in our fundamental understanding of these extraordinarily complex systems that must be resolved to reach a mature level of understanding. PMID:19176266

A Manual of Cherokee Herbal Remedies: History, Information, Identification, Medicinal Healing.

ERIC Educational Resources Information Center

Schafer, Patricia D.

This thesis reports on the research of 25 plants, used as herbal remedies since the 1800s by the author's Native American ancestors (the Day family) and the Cherokee tribe. The plants were identified in four state parks in southwestern Indiana. Information sources included the research literature, articles on Cherokee herbal remedies, and…

Differential endosomal sorting of a novel P2Y12 purinoreceptor mutant.

PubMed

Cunningham, Margaret R; Nisar, Shaista P; Cooke, Alexandra E; Emery, Elizabeth D; Mundell, Stuart J

2013-05-01

P2Y12 receptor internalization and recycling play an essential role in ADP-induced platelet activation. Recently, we identified a patient with a mild bleeding disorder carrying a heterozygous mutation of P2Y12 (P341A) whose P2Y12 receptor recycling was significantly compromised. Using human cell line models, we identified key proteins regulating wild-type (WT) P2Y12 recycling and investigated P2Y12 -P341A receptor traffic. Treatment with ADP resulted in delayed Rab5-dependent internalization of P341A when compared with WT P2Y12 . While WT P2Y12 rapidly recycled back to the membrane via Rab4 and Rab11 recycling pathways, limited P341A recycling was observed, which relied upon Rab11 activity. Although minimal receptor degradation was evident, P341A was localized in Rab7-positive endosomes with considerable agonist-dependent accumulation in the trans-Golgi network (TGN). Rab7 activity is known to facilitate recruitment of retromer complex proteins to endosomes to transport cargo to the TGN. Here, we identified that P341A colocalized with Vps26; depletion of which blocked limited recycling and promoted receptor degradation. This study has identified key points of divergence in the endocytic traffic of P341A versus WT-P2Y12 . Given that these pathways are retained in human platelets, this research helps define the molecular mechanisms regulating P2Y12 receptor traffic and explain the compromised receptor function in the platelets of the P2Y12 -P341A-expressing patient. © 2013 John Wiley & Sons A/S.

Using contaminated plants involved in phytoremediation for anaerobic digestion.

PubMed

Cao, Zewei; Wang, Shengxiao; Wang, Ting; Chang, Zhizhou; Shen, Zhenguo; Chen, Yahua

2015-01-01

This study investigated the anaerobic digestion capability of five plants and the effects of copper (Cu) and S,S'-ethylenediaminedisuccinic acid (EDDS, a chelator widely used in chelant-assisted phytoremediation) on biogas production to determine a feasible disposal method for plants used in remediation. The results showed that in addition to Phytolacca americana L., plants such as Zea mays L., Brassica napus L., Elsholtzia splendens Nakai ex F. Maekawa, and Oenothera biennis L. performed well in biogas production. Among these, O. biennis required the shortest period to finish anaerobic digestion. Compared to normal plants with low Cu content, the plants used in remediation with increased Cu levels (100 mg kg(-1)) not only promoted anaerobic digestion and required a shorter anaerobic digestion time, but also increased the methane content in biogas. When the Cu content in plants increased to 500, 1000, and 5000 mg kg(-1), the cumulative biogas production decreased by 12.3%, 14.6%, and 41.2%, respectively. Studies also found that EDDS conspicuously restrained biogas production from anaerobic digestion. The results suggest that anaerobic digestion has great potential for the disposal of contaminated plants and may provide a solution for the resource utilization of plants used in remediation.

Functional remediation components: A conceptual method of evaluating the effects of remediation on risks to ecological receptors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burger, Joanna; Gochfeld, Michael; Bunn, Amoret

2016-08-30

Governmental agencies, regulators, health professionals, tribal leaders, and the public are faced with understanding and evaluating the effects of cleanup activities on species, populations, and ecosystems. While engineers and managers understand the processes involved in different remediation types such as capping, pump and treat, and natural attenuation, there is often a disconnect between (1) how ecologists view the influence of different types of remediation, (2) how the public perceives them, and (3) how engineers understand them. The overall goal of the present investigation was to define the components of remediation types (= functional remediation). Objectives were to (1) define andmore » describe functional components of remediation, regardless of the remediation type, (2) provide examples of each functional remediation component, and (3) explore potential effects of functional remediation components in the post-cleanup phase that may involve continued monitoring and assessment. Functional remediation components include types, numbers, and intensity of people, trucks, heavy equipment, pipes, and drill holes, among others. Several components may be involved in each remediation type, and each results in ecological effects, ranging from trampling of plants, to spreading invasive species, to disturbing rare species, and to creating fragmented habitats. In some cases remediation may exert a greater effect on ecological receptors than leaving the limited contamination in place. A goal of this conceptualization is to break down functional components of remediation such that managers, regulators, and the public might assess the effects of timing, extent, and duration of different remediation options on ecological systems.« less

Y-12 Sustainability and Stewardship

ScienceCinema

John Krueger

2017-12-09

The Y-12 National Security Complex recently won a White House award for its leadership among Government installations for pollution prevention. This video tells the story of the many actions taken by this NNSA National Security Enterprise site towards being a responsible environmental citizen while protecting the national interest.

Y-12 Sustainability and Stewardship

DOE Office of Scientific and Technical Information (OSTI.GOV)

John Krueger

2009-10-06

The Y-12 National Security Complex recently won a White House award for its leadership among Government installations for pollution prevention. This video tells the story of the many actions taken by this NNSA National Security Enterprise site towards being a responsible environmental citizen while protecting the national interest.

Remediation of mercury-polluted soils using artificial wetlands.

PubMed

García-Mercadoa, Héctor Daniel; Fernándezb, Georgina; Garzón-Zúñigac, Marco Antonio; Durán-Domínguez-de-Bazúaa, María Del Carmen

2017-01-02

Mexico's mercury mining industry is important for economic development, but has unfortunately contaminated soils due to open-air disposal. This case was seen at two sites in the municipality of Pinal de Amoles, State of Queretaro, Mexico. This paper presents an evaluation of mercury dynamics and biogeochemistry in two soils (mining waste soil) using ex-situ wetlands over 36 weeks. In soils sampled in two former mines of Pinal de Amoles, initial mercury concentrations were 424 ± 29 and 433 ± 12 mg kg -1 in La Lorena and San Jose, former mines, respectively. Typha latifolia and Phragmites australis were used and 20 reactors were constructed (with and without plants). The reactors were weekly amended with a nutrient solution (NPK), for each plant, at a pH of 5.0. For remediation using soils from San Jose 70-78% of mercury was removed in T. latifolia reactors and 76-82% in P. australis reactors, and for remediation of soils from La Lorena, mercury content was reduced by 55-71% using T. latifolia and 58-66% in P. australis reactors. Mercury emissions into the atmosphere were estimated to be 2-4 mg m -2 h -1 for both soils.

Phytoremediation and innovative strategies for specialized remedial actions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alleman, B.C.; Leeson, A.

1999-01-01

Phytoremediation is a site remediation strategy whose time seems to have come in the past few years, with field implementations taking place in a host of applications. From laboratory studies on plant uptake to full-scale phytoremediation treatment strategies, this volume covers the use of plants to treat contaminants such as hydrocarbons, metals, pesticides, perchlorate, and chlorinated solvents. In addition to the phytoremediation studies, this volume also covers specialized remediation approaches such as sequential anaerobic/aerobic in situ treatment, membrane bioreactors, and Fenton's reagent oxidation.

Phytoremediation and innovative strategies for specialized remedial actions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alleman, B.C.; Leeson, A.

1999-11-01

Phytoremediation is a site remediation strategy whose time seems to have come in the past few years, with field implementations taking place in a host of applications. From laboratory studies on plant uptake to full-scale phytoremediation treatment strategies, this volume covers the use of plants to treat contaminants such as hydrocarbons, metals, pesticides, perchlorate, and chlorinated solvents. In addition to the phytoremediation studies, this volume also covers specialized remediation approaches such as sequential anaerobic/aerobic in situ treatment, membrane bioreactors, and Fenton`s reagent oxidation.

Phytoremediation and innovative strategies for specialized remedial applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alleman, B.C.; Leeson, A.

1999-10-01

Phytoremediation is a site remediation strategy whose time seems to have come in the past few years, with field implementations taking place in a host of applications. From laboratory studies on plant uptake to full-scale phytoremediation treatment strategies, this volume covers the use of plants to treat contaminants such as hydrocarbons, metals, pesticides, perchlorate, and chlorinated solvents. In addition to the phytoremediation studies, this volume also covers specialized remediation approaches such as sequential anaerobic/aerobic in situ treatment, membrane bioreactors, and Fenton`s reagent oxidation.

Vitamin B12-Containing Plant Food Sources for Vegetarians

PubMed Central

Watanabe, Fumio; Yabuta, Yukinori; Bito, Tomohiro; Teng, Fei

2014-01-01

The usual dietary sources of Vitamin B12 are animal-derived foods, although a few plant-based foods contain substantial amounts of Vitamin B12. To prevent Vitamin B12 deficiency in high-risk populations such as vegetarians, it is necessary to identify plant-derived foods that contain high levels of Vitamin B12. A survey of naturally occurring plant-derived food sources with high Vitamin B12 contents suggested that dried purple laver (nori) is the most suitable Vitamin B12 source presently available for vegetarians. Furthermore, dried purple laver also contains high levels of other nutrients that are lacking in vegetarian diets, such as iron and n-3 polyunsaturated fatty acids. Dried purple laver is a natural plant product and it is suitable for most people in various vegetarian groups. PMID:24803097

Cangrelor: A New Route for P2Y12 Inhibition.

PubMed

Sible, Alexandra M; Nawarskas, James J

Antiplatelet therapy with a P2Y12 inhibitor is a key component of treatment for patients with acute coronary syndromes undergoing percutaneous coronary intervention. Before the development of cangrelor (Kengreal, The Medicines Company, Parsippany, NJ), only oral P2Y12 inhibitors were available. Cangrelor is a reversible P2Y12 inhibitor that is administered as an intravenous infusion, and its quick onset and offset make it an appealing option for antiplatelet therapy, particularly for patients who are unable to take oral medications. Although cangrelor struggled to show benefit in early trials, the positive results of the CHAMPION PHOENIX trial led to its approval for use as an adjunct to percutaneous coronary intervention to reduce the risk of periprocedural myocardial infarction, repeat coronary revascularization, and stent thrombosis in patients who have not been treated with another P2Y12 inhibitor and are not being given a glycoprotein IIb/IIIa inhibitor. Cangrelor has also been evaluated as an option for bridging therapy in patients who must discontinue their oral P2Y12 inhibitor before coronary artery bypass grafting. This review of cangrelor will discuss its mechanism of action, its pharmacodynamics and pharmacokinetics, the clinical trial experience, and its potential place in therapy.

7 CFR 201.56-12 - Miscellaneous plant families.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Miscellaneous plant families. 201.56-12 Section 201.56-12 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Miscellaneous plant families. Kinds of seed by family: Carrot family, Apiaceae (Umbelliferae)—carrot, celery...

7 CFR 201.56-12 - Miscellaneous plant families.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Miscellaneous plant families. 201.56-12 Section 201.56-12 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Miscellaneous plant families. Kinds of seed by family: Carrot family, Apiaceae (Umbelliferae)—carrot, celery...

Phytoremediation: role of terrestrial plants and aquatic macrophytes in the remediation of radionuclides and heavy metal contaminated soil and water.

PubMed

Sharma, Sunita; Singh, Bikram; Manchanda, V K

2015-01-01

Nuclear power reactors are operating in 31 countries around the world. Along with reactor operations, activities like mining, fuel fabrication, fuel reprocessing and military operations are the major contributors to the nuclear waste. The presence of a large number of fission products along with multiple oxidation state long-lived radionuclides such as neptunium ((237)Np), plutonium ((239)Pu), americium ((241/243)Am) and curium ((245)Cm) make the waste streams a potential radiological threat to the environment. Commonly high concentrations of cesium ((137)Cs) and strontium ((90)Sr) are found in a nuclear waste. These radionuclides are capable enough to produce potential health threat due to their long half-lives and effortless translocation into the human body. Besides the radionuclides, heavy metal contamination is also a serious issue. Heavy metals occur naturally in the earth crust and in low concentration, are also essential for the metabolism of living beings. Bioaccumulation of these heavy metals causes hazardous effects. These pollutants enter the human body directly via contaminated drinking water or through the food chain. This issue has drawn the attention of scientists throughout the world to device eco-friendly treatments to remediate the soil and water resources. Various physical and chemical treatments are being applied to clean the waste, but these techniques are quite expensive, complicated and comprise various side effects. One of the promising techniques, which has been pursued vigorously to overcome these demerits, is phytoremediation. The process is very effective, eco-friendly, easy and affordable. This technique utilizes the plants and its associated microbes to decontaminate the low and moderately contaminated sites efficiently. Many plant species are successfully used for remediation of contaminated soil and water systems. Remediation of these systems turns into a serious problem due to various anthropogenic activities that have

Applicability of Phytoextraction with Arabidopsis halleri ssp. gemmifera to Remediate Cd-contaminated Andisols

NASA Astrophysics Data System (ADS)

Kameyama, Koji; Tani, Shigeru; Sugawara, Reiko; Ishikawa, Yuichi

The objective of this study was to investigate the applicability of phytoextraction with a Cd-hyperaccumulator plant (Arabidopsis halleri ssp. gemmifera) to remediate Cd-contaminated Andisols. Cd absorption potentials of this plant for Andisols were examined in pot experiments. Sequentially, phytoextraction durations for remediation of Cd-contaminated Andisols were calculated from the experimental data. The results were as follows: (1) Cd concentrations in the plant shoots ranged from 170-750 mgṡkg-1. (2) Cd absorption of the plant for Andisols with ALC (Autoclaved Lightweight aerated Concrete) was less than for Andisols without ALC. However, the plants absorbed the same amount of soil Cd extracted by 0.01 M HCl with or without ALC. (3) Calculations suggest that the applicability of phytoextraction with this plant is high for slightly contaminated Andisols. Therefore, phytoextraction with Arabidopsis halleri ssp. gemmifera may be a viable option for the remediation of Cd-contaminated Andisols.

P2Y12 expression and function in alternatively activated human microglia

PubMed Central

Ase, Ariel R.; Kinsara, Angham; Rao, Vijayaraghava T.S.; Michell-Robinson, Mackenzie; Leong, Soo Yuen; Butovsky, Oleg; Ludwin, Samuel K.; Séguéla, Philippe; Bar-Or, Amit; Antel, Jack P.

2015-01-01

Objective: To investigate and measure the functional significance of altered P2Y12 expression in the context of human microglia activation. Methods: We performed in vitro and in situ experiments to measure how P2Y12 expression can influence disease-relevant functional properties of classically activated (M1) and alternatively activated (M2) human microglia in the inflamed brain. Results: We demonstrated that compared to resting and classically activated (M1) human microglia, P2Y12 expression is increased under alternatively activated (M2) conditions. In response to ADP, the endogenous ligand of P2Y12, M2 microglia have increased ligand-mediated calcium responses, which are blocked by selective P2Y12 antagonism. P2Y12 antagonism was also shown to decrease migratory and inflammatory responses in human microglia upon exposure to nucleotides that are released during CNS injury; no effects were observed in human monocytes or macrophages. In situ experiments confirm that P2Y12 is selectively expressed on human microglia and elevated under neuropathologic conditions that promote Th2 responses, such as parasitic CNS infection. Conclusion: These findings provide insight into the roles of M2 microglia in the context of neuroinflammation and suggest a mechanism to selectively target a functionally unique population of myeloid cells in the CNS. PMID:25821842

Site-specific standard request for underground storage tanks 1219-U, 1222-U, 2082-U, and 2068-U at the rust garage facility buildings 9754-1 and 9720-15: Oak Ridge Y-12 Plant, Oak Ridge, Tennessee, Facility ID No. 0-010117

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-12-01

This document represents a Site-specific Standard Request for underground storage tanks (USTs) 1219-U,1222-U and 2082-U previously located at former Building 9754-1, and tank 2086-U previously located at Building 9720-15, Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. The tanks previously contained petroleum products. For the purposes of this report, the two building sites will be regarded as a single UST site and will be referred to as the Rust Garage Facility. The current land use associated with the Y-12 Plant is light industrial and the operational period of the plant is projected to be at least 30 years. Thus, potential futuremore » residential exposures are not expected to occur for at least 30 years. Based on the degradation coefficient for benzene (the only carcinogenic petroleum constituent detected in soils or groundwater at the Rust Garage Facility), it is expected that the benzene and other contaminants at the site will likely be reduced prior to expiration of the 30-year plant operational period. As the original sources of petroleum contamination have been removed, and the area of petroleum contamination is limited, a site-specific standard is therefore being requested for the Rust Garage Facility.« less

50 CFR 17.12 - Endangered and threatened plants.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 2 2012-10-01 2012-10-01 false Endangered and threatened plants. 17.12 Section 17.12 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) ENDANGERED...

50 CFR 17.12 - Endangered and threatened plants.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 2 2013-10-01 2013-10-01 false Endangered and threatened plants. 17.12 Section 17.12 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) ENDANGERED...

50 CFR 17.12 - Endangered and threatened plants.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 2 2014-10-01 2014-10-01 false Endangered and threatened plants. 17.12 Section 17.12 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) ENDANGERED...

Remedial investigation concept plan for the groundwater operable units at the chemical plant area and the ordnance works area, Weldon Spring, Missouri

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1999-07-15

The U.S. Department of Energy (DOE) and the U.S. Department of the Army (DA) are conducting cleanup activities at two properties--the DOE chemical plant area and the DA ordnance works area (the latter includes the training area)--located in the Weldon Spring area in St. Charles County, Missouri. These areas are on the National Priorities List (NPL), and cleanup activities at both areas are conducted in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. DOE and DA are conducting a joint remedial investigation (RI) and baseline risk assessment (BRA) as part of the remedial investigation/feasibility studymore » (RI/FS) for the groundwater operable units for the two areas. This joint effort will optimize further data collection and interpretation efforts and facilitate overall remedial decision making since the aquifer of concern is common to both areas. A Work Plan issued jointly in 1995 by DOE and the DA discusses the results of investigations completed at the time of preparation of the report. The investigations were necessary to provide an understanding of the groundwater system beneath the chemical plant area and the ordnance works area. The Work Plan also identifies additional data requirements for verification of the evaluation presented.« less

Magnetic properties of quadruple perovskite solid solutions Ca{sub 1–x}Y{sub x}Cu{sub 3}Fe{sub 4}O{sub 12} and Y{sub 1–y}Ce{sub x}Cu{sub 3}Fe{sub 4}O{sub 12}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murakami, Makoto; Mori, Shigeo; Yamada, Ikuya, E-mail: i-yamada@21c.osakafu-u.ac.jp

Magnetic properties of the quadruple perovskite solid solutions Ca{sub 1–x}Y{sub x}Cu{sub 3}Fe{sub 4}O{sub 12} and Y{sub 1–y}Ce{sub y}Cu{sub 3}Fe{sub 4}O{sub 12} are investigated. Ca{sub 1–x}Y{sub x}Cu{sub 3}Fe{sub 4}O{sub 12} shows continuous increase in the ferromagnetic transition temperature as x increases. Y{sub 1–y}Ce{sub y}Cu{sub 3}Fe{sub 4}O{sub 12} exhibits a ferromagnetic-antiferromagnetic transition in the vicinity of y = 0.5. These observations demonstrate the electron doping effect on magnetic properties of charge-disproportionated ACu{sub 3}Fe{sub 4}O{sub 12} phases.

Effects of different remediation treatments on crude oil contaminated saline soil.

PubMed

Gao, Yong-Chao; Guo, Shu-Hai; Wang, Jia-Ning; Li, Dan; Wang, Hui; Zeng, De-Hui

2014-12-01

Remediation of the petroleum contaminated soil is essential to maintain the sustainable development of soil ecosystem. Bioremediation using microorganisms and plants is a promising method for the degradation of crude oil contaminants. The effects of different remediation treatments, including nitrogen addition, Suaeda salsa planting, and arbuscular mycorrhiza (AM) fungi inoculation individually or combined, on crude oil contaminated saline soil were assessed using a microcosm experiment. The results showed that different remediation treatments significantly affected the physicochemical properties, oil contaminant degradation and bacterial community structure of the oil contaminated saline soil. Nitrogen addition stimulated the degradation of total petroleum hydrocarbon significantly at the initial 30d of remediation. Coupling of different remediation techniques was more effective in degrading crude oil contaminants. Applications of nitrogen, AM fungi and their combination enhanced the phytoremediation efficiency of S. salsa significantly. The main bacterial community composition in the crude oil contaminated saline soil shifted with the remediation processes. γ-Proteobacteria, β-Proteobacteria, and Actinobacteria were the pioneer oil-degraders at the initial stage, and Firmicutes were considered to be able to degrade the recalcitrant components at the later stage. Copyright © 2014 Elsevier Ltd. All rights reserved.

Proposed modifications to the RCRA post-closure permit for the Chestnut Ridge Hydrogeologic Regime at the U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-05-01

This report presents proposed modifications to several conditions of the Resource Conservation and Recovery Act (RCRA) Post-Closure Permit (PCP) for the Chestnut Ridge Hydrogeologic Regime (CRHR) (permit number TNHW-088, EPA ID No. TN3 89 009 0001). These permit conditions define the requirements for RCRA post-closure detection groundwater monitoring at the Chestnut Ridge Sediment Disposal Basin (CRSDB) and Kerr Hollow Quarry (KHQ), and RCRA post-closure corrective action groundwater monitoring at the Chestnut Ridge Security Pits (CRSPs). Modification of these PCP conditions is requested to: (1) clarify the planned integration of RCRA post-closure corrective action groundwater monitoring at the CRSPs with themore » monitoring program to be established in the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) record of decision (ROD), (2) revise several of the current technical requirements for groundwater monitoring based on implementation of the RCRA monitoring programs during 1996, (3) replace several of the technical procedures included in the PCP with updated versions recently issued by the Y-12 Plant Groundwater Protection Program (GWPP), and (4) correct inaccurate regulatory citations and references to permit conditions and permit attachments. With these modifications, the Y- 12 Plant will continue to meet the full intent of all regulatory obligations for post-closure care of these facilities. Section 2 provides the technical justification for each proposed permit modification. Section 3.0 contains proposed changes to Section II of the PCP. Modifications to site-specific permit conditions are presented in Section 4.0 (CRSDB), Section 5.0 (CRSPs), and Section 6.0 (KHQ). Sections 7.0 and 8.0 reference updated and revised procedures for groundwater sampling, and monitoring well plugging and abandonment, respectively. Appendix A includes all proposed revisions to the permit attachments.« less

Remediation of metalliferous mines, revegetation challenges and emerging prospects in semi-arid and arid conditions.

PubMed

Nirola, Ramkrishna; Megharaj, Mallavarapu; Beecham, Simon; Aryal, Rupak; Thavamani, Palanisami; Vankateswarlu, Kadiyala; Saint, Christopher

2016-10-01

Understanding plant behaviour in polluted soils is critical for the sustainable remediation of metal-polluted sites including abandoned mines. Post-operational and abandoned metal mines particularly in semi-arid and arid zones are one of the major sources of pollution by soil erosion or plant hyperaccumulation bringing ecological impacts. We have selected from the literature 157 species belonging to 50 families to present a global overview of 'plants under action' against heavy metal pollution. Generally, all species of plants that are drought, salt and metal tolerant are candidates of interest to deal with harsh environmental conditions, particularly at semi-arid and arid mine sites. Pioneer metallophytes namely Atriplex nummularia, Atriplex semibaccata, Salsola kali, Phragmites australis and Medicago sativa, representing the taxonomic orders Caryophyllales, Poales and Fabales are evaluated in terms of phytoremediation in this review. Phytoremediation processes, microbial and algal bioremediation, the use and implication of tissue culture and biotechnology are critically examined. Overall, an integration of available remediation plant-based technologies, referred to here as 'integrated remediation technology,' is proposed to be one of the possible ways ahead to effectively address problems of toxic heavy metal pollution. Graphical abstract Integrated remediation technology (IRT) in metal-contaminated semi-arid and arid conditions. The hexagonal red line represents an IRT concept based on remediation decisions by combination of plants and microbial processes.

Suitability of Scirpus maritimus for petroleum hydrocarbons remediation in a refinery environment.

PubMed

Couto, M Nazaré P F S; Basto, M Clara P; Vasconcelos, M Teresa S D

2012-01-01

In the ambit of a project searching for appropriate biological approaches for recovering a refinery soil contaminated with petroleum hydrocarbons (PHC), we compared results obtained in the absence and in the presence of the salt marsh plant Scirpus maritimus or Juncus maritimus or an association of these two plants, which were tested in the refinery environment. Synergistic effects caused by addition of a non-ionic surfactant and/or a bioaugmentation product were also investigated. Major challenges of this study were: field conditions and weathered contamination. Transplants of the plants were carried out in individual containers filled with a weathered contaminated soil, which was recontaminated with turbine oil with two purposes: for increasing PHC level and allowing a comparison of the potential of plants for remediation of ancient and recent contamination. Analysis of total PHC led to the conclusion that, after 24-month exposure, neither J. maritimus nor the association caused any improvement in remediation. In contrast, S. maritimus revealed potential for PHC remediation, favoring degradation of both recent and older contamination (which was refractory to natural attenuation). About 15% of remediation improvement was found in the soil layer with higher root density (5-10 cm). A more marked improvement in that layer (28%) was observed when non-ionic surfactant amendment and bioaugmentation were used jointly. The fact that S. maritimus has demonstrated capability for PHC remediation, leads to admit that it has potential to be also used for recovering sediments that have suffered accidental oil spills.

Assessment of the Use of Natural Materials for the Remediation of Cadmium Soil Contamination.

PubMed

de O Pinto, Tatiana; García, Andrés C; Guedes, Jair do N; do A Sobrinho, Nelson M B; Tavares, Orlando C H; Berbara, Ricardo L L

2016-01-01

Rice plants accumulate cadmium (Cd2+) within the grain, increasing the danger of human exposure. Natural materials have been used in soil remediation, but few studies have examined the risks (based on the bioavailability of these metals to plants) of using these materials, so the practice remains controversial. In the present study, we evaluated the effectiveness of biochar produced from sugarcane bagasse, vermicompost (VC), vermicompost solid residue (VCR) and humin for remediation of Cd2+-contaminated soils. We characterized the interactions between these materials and Cd2+ and evaluated their capacity to alter Cd2+ availability to rice plants. Our results show that under the conditions in this study, biochar and humin were not effective for soil remediation. Although biochar had high Cd2+ retention, it was associated with high Cd2+ bioavailability and increased Cd2+ accumulation in rice plants. VC and VCR had high Cd2+ retention capacity as well as low Cd2+ availability to plants. These characteristics were especially notable for VCR, which was most effective for soil remediation. The results of our study demonstrate that in the tested materials, the bioavailability of Cd2+ to plants is related to their structural characteristics, which in turn determine their retention of Cd2+.

Assessment of the Use of Natural Materials for the Remediation of Cadmium Soil Contamination

PubMed Central

de O. Pinto, Tatiana; García, Andrés C.; Guedes, Jair do N.; do A. Sobrinho, Nelson M. B.; Tavares, Orlando C. H.

2016-01-01

Rice plants accumulate cadmium (Cd2+) within the grain, increasing the danger of human exposure. Natural materials have been used in soil remediation, but few studies have examined the risks (based on the bioavailability of these metals to plants) of using these materials, so the practice remains controversial. In the present study, we evaluated the effectiveness of biochar produced from sugarcane bagasse, vermicompost (VC), vermicompost solid residue (VCR) and humin for remediation of Cd2+-contaminated soils. We characterized the interactions between these materials and Cd2+ and evaluated their capacity to alter Cd2+ availability to rice plants. Our results show that under the conditions in this study, biochar and humin were not effective for soil remediation. Although biochar had high Cd2+ retention, it was associated with high Cd2+ bioavailability and increased Cd2+ accumulation in rice plants. VC and VCR had high Cd2+ retention capacity as well as low Cd2+ availability to plants. These characteristics were especially notable for VCR, which was most effective for soil remediation. The results of our study demonstrate that in the tested materials, the bioavailability of Cd2+ to plants is related to their structural characteristics, which in turn determine their retention of Cd2+. PMID:27341440

Post-remediation use of macrophytes as composting materials for sustainable management of a sanitary landfill.

PubMed

Song, Uhram

2017-04-03

To increase the remediation ability and life expectancy of a leachate channel in a sanitary landfill, the plants used for remediation were composted as a post-remediation management technique. Phragmites australis or Typha angustifolia used for phytoremediation in a landfill leachate channel was harvested and used as a co-composting material with sewage sludge. The macrophyte compost was applied to the slope of a landfill on which plants were introduced for revegetation and to plants grown in pots to test for acute effects of the compost. The compost of the macrophytes successfully increased soil moisture and nutrient contents both on the landfill slope and in the soil of the pot experiment. Additionally, the rates of photosynthesis and the nutrient contents increased for plants grown in macrophyte compost. Thus, the revegetation or restoration management of the landfill would improve with the macrophyte compost used as a soil conditioner. The harvest of the macrophytes has the additional benefit of improving the remediation function of the leachate channel. Therefore, to sustainably manage both the leachate channel and the landfill, the composting of post-remediation macrophytes is an environmentally friendly and economically affordable method.

Superfund record of decision (EPA Region 6): Longhorn Army Ammunition Plant, Burning Ground Number 3, Karnack, TX, May 12, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This decision document presents the selected Early Interim Remedial Action for the Burning Ground No. 3 site (the site), Longhorn Army Ammunition Plant, in Karnack, Texas. The major components of the selected remedy include: extraction and Treatment of contaminated shallow groundwater using Organic Air Stripping and Off-gas Treatment and Metals precipitation, and Excavation and Treatment of Source Material using Low Temperature Thermal Desorption and Catalytic Oxidation for off-gas.

Sources of Mercury to East Fork Poplar Creek Downstream from the Y-12 National Security Complex: Inventories and Export Rates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Southworth, George R; Greeley Jr, Mark Stephen; Peterson, Mark J

2010-02-01

East Fork Poplar Creek (EFPC) in Oak Ridge, Tennessee, has been heavily contaminated with mercury (also referred to as Hg) since the 1950s as a result of historical activities at the U.S. Department of Energy (DOE) Y-12 National Security Complex (formerly the Oak Ridge Y-12 Plant and hereinafter referred to as Y-12). During the period from 1950 to 1963, spills and leaks of elemental mercury (Hg{sup 0}) contaminated soil, building foundations, and subsurface drainage pathways at the site, while intentional discharges of mercury-laden wastewater added 100 metric tons of mercury directly to the creek (Turner and Southworth 1999). The inventorymore » of mercury estimated to be lost to soil and rock within the facility was 194 metric tons, with another estimated 70 metric tons deposited in floodplain soils along the 25 km length of EFPC (Turner and Southworth 1999). Remedial actions within the facility reduced mercury concentrations in EFPC water at the Y-12 boundary from > 2500 ng/L to about 600 ng/L by 1999 (Southworth et al. 2000). Further actions have reduced average total mercury concentration at that site to {approx}300 ng/L (2009 RER). Additional source control measures planned for future implementation within the facility include sediment/soil removal, storm drain relining, and restriction of rainfall infiltration within mercury-contaminated areas. Recent plans to demolish contaminated buildings within the former mercury-use areas provide an opportunity to reconstruct the storm drain system to prevent the entry of mercury-contaminated water into the flow of EFPC. Such actions have the potential to reduce mercury inputs from the industrial complex by perhaps as much as another 80%. The transformation and bioaccumulation of mercury in the EFPC ecosystem has been a perplexing subject since intensive investigation of the issue began in the mid 1980s. Although EFPC was highly contaminated with mercury (waterborne mercury exceeded background levels by 1000-fold

Rapid Y degeneration and dosage compensation in plant sex chromosomes

PubMed Central

Papadopulos, Alexander S. T.; Chester, Michael; Ridout, Kate; Filatov, Dmitry A.

2015-01-01

The nonrecombining regions of animal Y chromosomes are known to undergo genetic degeneration, but previous work has failed to reveal large-scale gene degeneration on plant Y chromosomes. Here, we uncover rapid and extensive degeneration of Y-linked genes in a plant species, Silene latifolia, that evolved sex chromosomes de novo in the last 10 million years. Previous transcriptome-based studies of this species missed unexpressed, degenerate Y-linked genes. To identify sex-linked genes, regardless of their expression, we sequenced male and female genomes of S. latifolia and integrated the genomic contigs with a high-density genetic map. This revealed that 45% of Y-linked genes are not expressed, and 23% are interrupted by premature stop codons. This contrasts with X-linked genes, in which only 1.3% of genes contained stop codons and 4.3% of genes were not expressed in males. Loss of functional Y-linked genes is partly compensated for by gene-specific up-regulation of X-linked genes. Our results demonstrate that the rate of genetic degeneration of Y-linked genes in S. latifolia is as fast as in animals, and that the evolutionary trajectories of sex chromosomes are similar in the two kingdoms. PMID:26438872

Technique for rapid establishment of American lotus in remediation efforts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryon, M. G.; Jett, R. T.; McCracken, M. K.

A technique for increasing the establishment rate of American lotus (Nelumbo lutea) and simplifying planting was developed as part of a pond remediation project. Lotus propagation techniques typically require scarification of the seed, germination in heated water, and planting in nursery containers. Then mature (~ 1 yr) nursery-grown stock is transferred to planting site or scarified seed are broadcast applied. Mature plants should grow more quickly, but can be sensitive to handling, require more time to plant, and cost more. Scarified seeds are easier to plant and inexpensive, but have a lag time in growth, can fail to germinate, andmore » can be difficult to site precisely. We developed an intermediate technique using small burlap bags that makes planting easier, provides greater germination success, and avoids lag time in growth. Data on survival and growth from experiments using mature stock, scarified seeds, and bag lotus demonstrate that bag lotus grow rapidly in a variety of conditions, have a high survival rate, can be processed and planted easily and quickly, and are very suitable for a variety of remediation projects« less

Remediation of lead and cadmium-contaminated soils.

PubMed

Salama, Ahmed K; Osman, Khaled A; Gouda, Neama Abdel-Razeek

2016-01-01

The research was designated to study the ability of plants to bio-accumulate, translocate and remove the heavy metals, lead and cadmium from contaminated soil. The herbal plant ryegrass, Lolium multiflorum was investigated as a bio-accumulator plant for these metals. The translocation of these heavy metals in the herbal plant was compared considering root to shoot transport and redistribution of metals in the root and shoot system. The trace metal contents from root and shoot parts were determined using atomic absorption spectrometer. The results showed that the percent of lead and cadmium transferred to ryegrass plant were averaged as 51.39, and 74.57%, respectively, while those remained in the soil were averaged as 48.61 and 25.43% following 60 days of treatment. The soil-plant transfer index in root and shoot system of ryegrass was found to be 0.32 and 0.20 for lead, and 0.50 and 0.25 for cadmium. These findings indicated that the herbal plant ryegrass, Lolium multiflorum is a good accumulator for cadmium than lead. The soil-plant transfer factor (the conc. of heavy metal in plant to the conc. in soil) indicated that the mechanism of soil remedy using the investigated plant is phytoextraction where the amounts of heavy metals transferred by plant roots into the above ground portions were higher than that remained in the soil. The method offers green technology solution for the contamination problem since it is effective technology with minimal impact on the environment and can be easily used for soil remedy.

Y-12 Groundwater Protection Program Monitoring Optimization Plan for Groundwater Monitoring Wells at the U.S. Department of Energy Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

This document is the monitoring optimization plan for groundwater monitoring wells associated with the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) in Oak Ridge, Tennessee. The plan describes the technical approach that is implemented under the Y-12 Groundwater Protection Program (GWPP) to focus available resources on the monitoring wells at Y-12 that provide the most useful hydrologic and groundwater quality monitoring data. The technical approach is based on the GWPP status designation for each well. Under this approach, wells granted “active” status are used by the GWPP for hydrologic monitoring and/or groundwater quality sampling, whereas wells grantedmore » “inactive” status are not used for either purpose. The status designation also defines the frequency at which the GWPP will inspect applicable wells, the scope of these well inspections, and extent of any maintenance actions initiated by the GWPP. Details regarding the ancillary activities associated with implementation of this plan (e.g., well inspection) are deferred to the referenced GWPP plans.« less

IMPROVED RISK ASSESSMENT AND REMEDIATION OF SOIL METALS BASED ON BIOAVAILABILITY MEASUREMENTS

EPA Science Inventory

Heavy metals in soils can comprise risk through plant uptake or soil ingestion. Recent research results and progress in understandings of risks and methods for soil metal remediation will be presented. Beneficial use of composts/bosolids plus limestone to remediate metal killed e...

Landfill Remediation Feasibility Study, Devens, Massachusetts. Volume 1. Text, Figures, and Tables

DTIC Science & Technology

1997-01-01

REMEDIATION FEASIBILITY STUDY DEVENS , MA Remedial Action Alternative Retained Eliminated PA-i: Cap-in-Place AOCs 9, 11, 40, 41 X Excavate/Dispose... AOC * 9 & 40 LANDFILL REMEDIATION FEASIBIUTY STUDY DEVENS , MA DIRECT COSTS NO FURTHER ACTION SA 6 $ 0 SA 12 0 SA 13 0 AOC 41 0 LIMITED REMOVAL AT AOC ... Fort Devens ), Devens , Massachusetts. 11 12 The FS is being conducted in accordance with the U.S. Environmental

[Manuscript "Many different remedies for headache treatment" from the archives of Sinj Friary].

PubMed

Kujundzic, Nikola; Glibota, Milan; Inic, Suzana

2011-01-01

Manuscripts containing collections of folk recipes for treatment of deseases were written mostly by Catholic priests especially Franciscians in Croatia in the past centuries. They were used as manuals for preparation of remedies and gave directions for their use. These writtings provide valuble data for etnographers and historians of ethnomedicine. The paper describes the manuscript "Many different remedies for headache treatment" written by unknown author probably in 18. century in Sinj, Dalmatia. The manuscript was found in the archives of Sinj Friary. The collection contains 16 recipes for headache treatment. Materia medica of the manuscript is composed of drugs of plant origin. Valuable information is given about the folk names for medicinal plants as well as descriptions of the ways of preparing remedies. Latin as well as contemporaly croatian names are attributed to the plants species mentioned in the manuscript. Use of the plants for treatment of the specific deseases were compared with their use in modern fitotherapy.

30 CFR 827.12 - Coal preparation plants: Performance standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Coal preparation plants: Performance standards...-COAL PREPARATION PLANTS NOT LOCATED WITHIN THE PERMIT AREA OF A MINE § 827.12 Coal preparation plants..., modification, reclamation, and removal activities at coal preparation plants shall comply with the following...

30 CFR 827.12 - Coal preparation plants: Performance standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Coal preparation plants: Performance standards...-COAL PREPARATION PLANTS NOT LOCATED WITHIN THE PERMIT AREA OF A MINE § 827.12 Coal preparation plants..., modification, reclamation, and removal activities at coal preparation plants shall comply with the following...

30 CFR 827.12 - Coal preparation plants: Performance standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Coal preparation plants: Performance standards...-COAL PREPARATION PLANTS NOT LOCATED WITHIN THE PERMIT AREA OF A MINE § 827.12 Coal preparation plants..., modification, reclamation, and removal activities at coal preparation plants shall comply with the following...

30 CFR 827.12 - Coal preparation plants: Performance standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Coal preparation plants: Performance standards...-COAL PREPARATION PLANTS NOT LOCATED WITHIN THE PERMIT AREA OF A MINE § 827.12 Coal preparation plants..., modification, reclamation, and removal activities at coal preparation plants shall comply with the following...

30 CFR 827.12 - Coal preparation plants: Performance standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Coal preparation plants: Performance standards...-COAL PREPARATION PLANTS NOT LOCATED WITHIN THE PERMIT AREA OF A MINE § 827.12 Coal preparation plants..., modification, reclamation, and removal activities at coal preparation plants shall comply with the following...

Milan Army Ammunition Plant remedial investigation report: Volume 1. Final report 89-91

DOE Office of Scientific and Technical Information (OSTI.GOV)

Okusu, N.; Hall, H.; Orndorff, A.

1991-12-09

A Remedial Investigation at the Milan Army Ammunition Plant, TN, was conducted for the US Army Toxic and Hazardous Materials Agency, under the terms of an Interagency Agreement with the State of Tennessee and the US Environmental Protection Agency. The study focused on the CERCLA site and selected RCRA regulated units identified by previous studies as potential sources of contamination. A broad range of chemicals including metals, explosives, and other organic compounds were found in source areas and in groundwater. The results of a risk assessment indicate that unacceptable levels of human health risks potentially exist. Conceptual models of sitemore » and unit characteristics were formulated to explain major findings, and areas not contributing to the problem were identified. For many source areas, major unknowns exist regarding hydrology, extent of contamination, and current and future impacts to groundwater quality.« less

Purinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host Response.

PubMed

Muniz, Valdirene S; Baptista-Dos-Reis, Renata; Benjamim, Claudia F; Mata-Santos, Hilton A; Pyrrho, Alexandre S; Strauch, Marcelo A; Melo, Paulo A; Vicentino, Amanda R R; Silva-Paiva, Juliana; Bandeira-Melo, Christianne; Weller, Peter F; Figueiredo, Rodrigo T; Neves, Josiane S

2015-01-01

Identifying new target molecules through which eosinophils secrete their stored proteins may reveal new therapeutic approaches for the control of eosinophilic disorders such as host immune responses to parasites. We have recently reported the expression of the purinergic P2Y12 receptor (P2Y12R) in human eosinophils; however, its functional role in this cell type and its involvement in eosinophilic inflammation remain unknown. Here, we investigated functional roles of P2Y12R in isolated human eosinophils and in a murine model of eosinophilic inflammation induced by Schistosoma mansoni (S. mansoni) infection. We found that adenosine 5'-diphosphate (ADP) induced human eosinophils to secrete eosinophil peroxidase (EPO) in a P2Y12R dependent manner. However, ADP did not interfere with human eosinophil apoptosis or chemotaxis in vitro. In vivo, C57Bl/6 mice were infected with cercariae of the Belo Horizonte strain of S. mansoni. Analyses performed 55 days post infection revealed that P2Y12R blockade reduced the granulomatous hepatic area and the eosinophilic infiltrate, collagen deposition and IL-13/IL-4 production in the liver without affecting the parasite oviposition. As found for humans, murine eosinophils also express the P2Y12R. P2Y12R inhibition increased blood eosinophilia, whereas it decreased the bone marrow eosinophil count. Our results suggest that P2Y12R has an important role in eosinophil EPO secretion and in establishing the inflammatory response in the course of a S. mansoni infection.

Platelets Express Activated P2Y12 Receptor in Patients With Diabetes Mellitus.

PubMed

Hu, Liang; Chang, Lin; Zhang, Yan; Zhai, Lili; Zhang, Shenghui; Qi, Zhiyong; Yan, Hongmei; Yan, Yan; Luo, Xinping; Zhang, Si; Wang, Yiping; Kunapuli, Satya P; Ye, Hongying; Ding, Zhongren

2017-08-29

Platelets from patients with diabetes mellitus are hyperactive. Hyperactivated platelets may contribute to cardiovascular complications and inadequate responses to antiplatelet agents in the setting of diabetes mellitus. However, the underlying mechanism of hyperactivated platelets is not completely understood. We measured P2Y 12 expression on platelets from patients with type 2 diabetes mellitus and on platelets from rats with diabetes mellitus. We also assayed platelet P2Y 12 activation by measuring cAMP and VASP phosphorylation. The antiplatelet and antithrombotic effects of AR-C78511 and cangrelor were compared in rats. Finally, we explored the role of the nuclear factor-κB pathway in regulating P2Y 12 receptor expression in megakaryocytes. Platelet P2Y 12 levels are 4-fold higher in patients with type 2 diabetes mellitus compared with healthy subjects. P2Y 12 expression correlates with ADP-induced platelet aggregation (r=0.89, P <0.01). P2Y 12 in platelets from patients with diabetes mellitus is constitutively activated. Although both AR-C78511, a potent P2Y 12 inverse agonist, and cangrelor have similar antiplatelet efficacy on platelets from healthy subjects, AR-C78511 exhibits more powerful antiplatelet effects on diabetic platelets than cangrelor (aggregation ratio 36±3% versus 49±5%, respectively, P <0.05). Using a FeCl 3 -injury mesenteric arteriole thrombosis model in rats and an arteriovenous shunt thrombosis model in rats, we found that the inverse agonist AR-C78511 has greater antithrombotic effects on GK rats with diabetes mellitus than cangrelor (thrombus weight 4.9±0.3 mg versus 8.3±0.4 mg, respectively, P <0.01). We also found that a pathway involving high glucose-reactive oxygen species-nuclear factor-κB increases platelet P2Y 12 receptor expression in diabetes mellitus. Platelet P2Y 12 receptor expression is significantly increased and the receptor is constitutively activated in patients with type 2 diabetes mellitus, which contributes to

The use of a halophytic plant species and organic amendments for the remediation of a trace elements-contaminated soil under semi-arid conditions.

PubMed

Clemente, Rafael; Walker, David J; Pardo, Tania; Martínez-Fernández, Domingo; Bernal, M Pilar

2012-07-15

The halophytic shrub Atriplex halimus L. was used in a field phytoremediation experiment in a semi-arid area highly contaminated by trace elements (As, Cd, Cu, Mn, Pb and Zn) within the Sierra Minera of La Unión-Cartagena (SE Spain). The effects of compost and pig slurry on soil conditions and plant growth were determined. The amendments (particularly compost) only slightly affected trace element concentrations in soil pore water or their availability to the plants, increased soil nutrient and organic matter levels and favoured the development of a sustainable soil microbial biomass (effects that were enhanced by the presence of A. halimus) as well as, especially for slurry, increasing A. halimus biomass and ground cover. With regard to the minimisation of trace elements concentrations in the above-ground plant parts, the effectiveness of both amendments was greatest 12-16 months after their incorporation. The findings demonstrate the potential of A. halimus, particularly in combination with an organic amendment, for the challenging task of the phytostabilisation of contaminated soils in (semi-)arid areas and suggest the need for an ecotoxicological evaluation of the remediated soils. However, the ability of A. halimus to accumulate Zn and Cd in the shoot may limit its use to moderately-contaminated sites. Copyright © 2012 Elsevier B.V. All rights reserved.

HABIT CHANGES OF Y3Al5O12 AND Y3Ga5O12 GROWN FROM A PbO-PbF2 FLUX,

DTIC Science & Technology

Al2O3 or - Ga2O3 ratio in the melt. Y3Ga5O12 crystals have a pure (211) habit when grown from either a Y2O3- or PbO-rich melt. The crystals develop...small (110) faces when grown from a Ga2O3 - or PbF2-rich melt. Y3Al5O12 crystals have a pure (110) when grown from either a PbF2- or Al2O3-rich melt... Ga2O3 -rich melts. It is believed that the habit variations are caused by changes in either the surface diffusion or step propagation, due to Pb

Natural Remediation at Savannah River Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, C. M.; Van Pelt, R.

2002-02-25

Natural remediation is a general term that includes any technology or strategy that takes advantage of natural processes to remediate a contaminated media to a condition that is protective of human health and the environment. Natural remediation techniques are often passive and minimally disruptive to the environment. They are generally implemented in conjunction with traditional remedial solutions for source control (i.e., capping, stabilization, removal, soil vapor extraction, etc.). Natural remediation techniques being employed at Savannah River Site (SRS) include enhanced bio-remediation, monitored natural attenuation, and phytoremediation. Enhanced bio-remediation involves making nutrients available and conditions favorable for microbial growth. With propermore » precautions and feeding, the naturally existing microbes flourish and consume the contaminants. Case studies of enhanced bio-remediation include surface soils contaminated with PCBs and pesticides, and Volatile Organic Compound (VOC) contamination in both the vadose zone and groundwater. Monitored natural attenuation (MNA) has been selected as the preferred alternative for groundwater clean up at several SRS waste units. Successful implementation of MNA has been based on demonstration that sources have been controlled, groundwater modeling that indicates that plumes will not expand or reach surface water discharge points at levels that exceed regulatory limits, and continued monitoring. Phytoremediation is being successfully utilized at several SRS waste units. Phytoremediation involves using plants and vegetation to uptake, break down, or manage contaminants in groundwater or soils. Case studies at SRS include managing groundwater plumes of tritium and VOCs with pine trees that are native to the area. Significant decreases in tritium discharge to a site stream have been realized in one phytoremediation project. Studies of other vegetation types, methods of application, and other target contaminants

Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation

PubMed Central

CHANG, H.; YANACHKOV, I. B.; DIX, E. J.; LI, Y. F.; BARNARD, M. R.; WRIGHT, G. E.; MICHELSON, A. D.; FRELINGER, A. L.

2017-01-01

Summary Background Diadenosine 5′,5‴-P1,P4-tetraphosphate (Ap4A), a natural compound stored in platelet dense granules, inhibits ADP-induced platelet aggregation. Ap4A inhibits the platelet ADP receptors P2Y1 and P2Y12, is a partial agonist of P2Y12, and is a full agonist of the platelet ATP-gated ion channel P2X1. Modification of the Ap4A tetraphosphate backbone enhances inhibition of ADP-induced platelet aggregation. However, the effects of these Ap4A analogs on human platelet P2Y1, P2Y12 and P2X1 are unclear. Objective To determine the agonist and antagonist activities of diadenosine tetraphosphate analogs towards P2Y1, P2Y12, and P2X1. Methods We synthesized the following Ap4A analogs: P1,P4-dithiotetraphosphate; P2,P3-chloromethylenetetraphosphate; P1-thio-P2,P3-chloromethylenetetraphosphate; and P1,P4-dithio-P2,P3-chloromethylenetetraphosphate. We then measured the effects of these analogs on: (i) ADP-induced platelet aggregation; (ii) P2Y1-mediated changes in cytosolic Ca2+; (iii) P2Y12-mediated changes in vasodilator-stimulated phosphoprotein phosphorylation; and (iv) P2X1-mediated entry of extracellular Ca2+. Results Ap4A analogs with modifications in the phosphate backbone inhibited both P2Y1 and P2Y12, and showed no agonist activity towards these receptors. The dithio modification increased inhibition of P2Y1, P2Y12, and platelet aggregation, whereas the chloromethylene modification increased inhibition of P2Y12 and platelet aggregation, but decreased P2Y1 inhibition. Combining the dithio and chloromethylene modifications increased P2Y1 and P2Y12 inhibition. As compared with Ap4A, each modification decreased agonist activity towards P2X1, and the dual modification completely eliminated P2X1 agonist activity. Conclusions As compared with Ap4A, tetraphosphate backbone analogs of Ap4A have diminished activity towards P2X1 but inhibit both P2Y1 and P2Y12 and, with greater potency, inhibit ADP-induced platelet aggregation. Thus, diadenosine tetraphosphate

Herbal remedies use by breast cancer patients in the West Bank of Palestine.

PubMed

Jaradat, Nidal Amin; Shawahna, Ramzi; Eid, Ahmad Mustafa; Al-Ramahi, Rowa; Asma, Maes Kasem; Zaid, Abdel Naser

2016-02-03

Recent ethnopharmacological surveys showed that herbal remedies are the most preferred modality of complementary and alternative medicine (CAM). In Palestine as in many other countries, herbal remedies are widely used in the treatment of many diseases. The aim of this study was to investigate the use of herbal remedies by women living with breast cancer in the West Bank of Palestine. This study was a questionnaire based cross-sectional descriptive study on the use of herbal remedies by breast cancer patients in the West Bank. A questionnaire was distributed to 115 patients at outpatient cancer clinics in face to face interviews. The study had a response rate of 89.6%. Of all respondents, 68% were herbal remedies users. Women with breast cancer used 46 plant species belonging to 32 families. Of these, Brassicaceae and Lamiaceae were the most prevalent. Ephedra alata was the most commonly used plant species in the treatment of breast cancer. Leaves and seeds were the most commonly used parts and decoction was the most commonly used method of preparation. Herbal remedies users were more likely to use herbal remedies instead of chemotherapy. The most commonly stated reason for using herbal remedies was the belief in boosting the patient's immune system to fight cancer. The use of herbal remedies is prevalent in breast cancer patients in Palestine. The use of herbal remedies was associated with educational level, time since diagnosis, type of surgery use, and use of endocrine therapy. It was apparent that the majority of users were satisfied with herbal remedies use. Clinical trials and pharmacological tests are required to be established for the presence of side effects, toxicity and efficacy for these herbal remedies. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

To fail is human: remediating remediation in medical education.

PubMed

Kalet, Adina; Chou, Calvin L; Ellaway, Rachel H

2017-12-01

Remediating failing medical learners has traditionally been a craft activity responding to individual learner and remediator circumstances. Although there have been moves towards more systematic approaches to remediation (at least at the institutional level), these changes have tended to focus on due process and defensibility rather than on educational principles. As remediation practice evolves, there is a growing need for common theoretical and systems-based perspectives to guide this work. This paper steps back from the practicalities of remediation practice to take a critical systems perspective on remediation in contemporary medical education. In doing so, the authors acknowledge the complex interactions between institutional, professional, and societal forces that are both facilitators of and barriers to effective remediation practices. The authors propose a model that situates remediation within the contexts of society as a whole, the medical profession, and medical education institutions. They also outline a number of recommendations to constructively align remediation principles and practices, support a continuum of remediation practices, destigmatize remediation, and develop institutional communities of practice in remediation. Medical educators must embrace a responsible and accountable systems-level approach to remediation if they are to meet their obligations to provide a safe and effective physician workforce.

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries

PubMed Central

André, Patrick; Delaney, Suzanne M.; LaRocca, Thomas; Vincent, Diana; DeGuzman, Francis; Jurek, Marzena; Koller, Beverley; Phillips, David R.; Conley, Pamela B.

2003-01-01

The critical role for ADP in arterial thrombogenesis was established by the clinical success of P2Y12 antagonists, currently used at doses that block 40–50% of the P2Y12 on platelets. This study was designed to determine the role of P2Y12 in platelet thrombosis and how its complete absence affects the thrombotic process. P2Y12-null mice were generated by a gene-targeting strategy. Using an in vivo mesenteric artery injury model and real-time continuous analysis of the thrombotic process, we observed that the time for appearance of first thrombus was delayed and that only small, unstable thrombi formed in P2Y12–/– mice without reaching occlusive size, in the absence of aspirin. Platelet adhesion to vWF was impaired in P2Y12–/– platelets. While adhesion to fibrinogen and collagen appeared normal, the platelets in thrombi from P2Y12–/– mice on collagen were less dense and less activated than their WT counterparts. P2Y12–/– platelet activation was also reduced in response to ADP or a PAR-4–activating peptide. Thus, P2Y12 is involved in several key steps of thrombosis: platelet adhesion/activation, thrombus growth, and stability. The data suggest that more aggressive strategies of P2Y12 antagonism will be antithrombotic without the requirement of aspirin cotherapy and may provide benefits even to the aspirin-nonresponder population. PMID:12897207

Studies on the individual and combined diuretic effects of four Vietnamese traditional herbal remedies (Zea mays, Imperata cylindrica, Plantago major and Orthosiphon stamineus).

PubMed

Doan, D D; Nguyen, N H; Doan, H K; Nguyen, T L; Phan, T S; van Dau, N; Grabe, M; Johansson, R; Lindgren, G; Stjernström, N E

1992-06-01

Herbal remedies are widely used in Vietnam alongside modern drugs. We assessed the diuretic effect of four traditional Vietnamese herbal remedies from Zea mays, Imperata cylindrica, Plantago major and Orthosiphon stamineus, all claimed to produce an increase of diuresis. No influence was recorded for the 12- and 24-h urine output or on the sodium excretion for any of the drugs when tested under standardized conditions in a placebo controlled double-blind crossover model. The present study indicates the need for critical review of the present recommendations regarding therapy with plant materials in countries relying on empiric traditions.

Ricinus communis L. A Value Added Crop for Remediation of Cadmium Contaminated Soil.

PubMed

Bauddh, Kuldeep; Singh, Kripal; Singh, Rana P

2016-02-01

Heavy metal pollution of soil is a global environmental problem and therefore its remediation is of paramount importance. Cadmium (Cd) is a potential toxicant to living organisms and even at very low concentrations. This study was aimed to assess the effectiveness of Ricinus communis for remediation of Cd contaminated soils. For this, growth and biomass of R. communis and Cd accumulation, translocation and partitioning in different plant parts were investigated after 8 months of plant growth in Cd contaminated soil (17.50 mg Cd kg−1 soil). Eight months old plants stabilized 51 % Cd in its roots and rest of the metal was transferred to the stem and leaves. There were no significant differences in growth, biomass and yield between control and Cd treated plants, except fresh weight of shoots. The seed yield per plant was reduced only by 5 % of Cd contaminated plants than control. The amount of Cd translocated to the castor seeds was nominal i.e. 0.007 µg Cd g−1 seeds. The bioconcentration factor reduced significantly in shoots and seeds in comparison to roots. The data indicates that R. communis is highly tolerant to Cd contamination and can be used for remediation of heavy metal polluted sites.

12. OBLIQUE VIEW OF NORTH WORK ROOM IN FILTRATION PLANT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. OBLIQUE VIEW OF NORTH WORK ROOM IN FILTRATION PLANT (#1773), LOOKING NORTHWEST - Presidio Water Treatment Plant, Filtration Plant, East of Lobos Creek at Baker Beach, San Francisco, San Francisco County, CA

Dermatological remedies in the traditional pharmacopoeia of Vulture-Alto Bradano, inland southern Italy

PubMed Central

Quave, Cassandra L; Pieroni, Andrea; Bennett, Bradley C

2008-01-01

Background Dermatological remedies make up at least one-third of the traditional pharmacopoeia in southern Italy. The identification of folk remedies for the skin is important both for the preservation of traditional medical knowledge and in the search for novel antimicrobial agents in the treatment of skin and soft tissue infection (SSTI). Our goal is to document traditional remedies from botanical, animal, mineral and industrial sources for the topical treatment of skin ailments. In addition to SSTI remedies for humans, we also discuss certain ethnoveterinary applications. Methods Field research was conducted in ten communities in the Vulture-Alto Bradano area of the Basilicata province, southern Italy. We randomly sampled 112 interviewees, stratified by age and gender. After obtaining prior informed consent, we collected data through semi-structured interviews, participant-observation, and small focus groups techniques. Voucher specimens of all cited botanic species were deposited at FTG and HLUC herbaria located in the US and Italy. Results We report the preparation and topical application of 116 remedies derived from 38 plant species. Remedies are used to treat laceration, burn wound, wart, inflammation, rash, dental abscess, furuncle, dermatitis, and other conditions. The pharmacopoeia also includes 49 animal remedies derived from sources such as pigs, slugs, and humans. Ethnoveterinary medicine, which incorporates both animal and plant derived remedies, is addressed. We also examine the recent decline in knowledge regarding the dermatological pharmacopoeia. Conclusion The traditional dermatological pharmacopoeia of Vulture-Alto Bradano is based on a dynamic folk medical construct of natural and spiritual illness and healing. Remedies are used to treat more than 45 skin and soft tissue conditions of both humans and animals. Of the total 165 remedies reported, 110 have never before been published in the mainland southern Italian ethnomedical literature. PMID

50 CFR 17.12 - Endangered and threatened plants.

Code of Federal Regulations, 2013 CFR

2013-10-01

... (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF... threatened plants. (h) * * * § 17.12, Note Species Scientific name Common name Historic range Family Status.... (TX) Brassicaceae E 814 17.96(a) NA ******* § 17.12, Note Effective Date Note 3: At 78 FR 60651, Oct...

Annual Storm Water Report for the Y-12 National Security Complex Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This is the second annual storm water report prepared in accordance with the National Pollutant Discharge Elimination System (NPDES) permit issued to the Y-12 National Security Complex (Y-12 Complex) on December 1, 2011, and the corresponding Y-12 Storm Water Pollution Prevention Plan (SWP3) which became effective on September 7, 2012. However, Appendix A does contain some analytical data gathered under the previous NPDES permit and SWP3 for comparison purposes. The quality of storm water exiting the Y-12 Complex via East Fork Poplar Creek remained relatively stable from 2012 to 2013. However, there was one largely unexpected high concentration of mercurymore » noted in an area that is not known to have previously been a mercury use area. This was noted in Sector AA, Outfall 014. This outfall is normally sampled on a rotating basis but, due this elevated concentration, will be sampled again in 2014. The Y-12 Complex will continue to implement appropriate BMPs and reduce outside material storage ares where possible. Emphasis will continue to be placed on site inspections and timely implementation of proper storm water control measures.« less

CHARACTERIZATION OF H-Y AND CR-Y ZEOLITE CATALYSTS DURING THE OXIDATIVE DESTRUCTION OF CFC11 AND CFC12

EPA Science Inventory

The long term stability-deactivation characteristics of two Y zeolite catalysts, namely H-Y and cation exchanged Cr-Y, were studied during the oxidative destruction of CFC11 and CFC12 feeds. Experiments were carried out at 300 degrees C and 500 h-1 space velocity. Properties of...

Technology Evaluation for the Big Spring Water Treatment System at the Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Becthel Jacobs Company LLC

2002-11-01

The Y-12 National Security Complex (Y-12 Complex) is an active manufacturing and developmental engineering facility that is located on the U.S. Department of Energy (DOE) Oak Ridge Reservation. Building 9201-2 was one of the first process buildings constructed at the Y-12 Complex. Construction involved relocating and straightening of the Upper East Fork Poplar Creek (UEFPC) channel, adding large quantities of fill material to level areas along the creek, and pumping of concrete into sinkholes and solution cavities present within the limestone bedrock. Flow from a large natural spring designated as ''Big Spring'' on the original 1943 Stone & Webster Buildingmore » 9201-2 Field Sketch FS6003 was captured and directed to UEFPC through a drainpipe designated Outfall 51. The building was used from 1953 to 1955 for pilot plant operations for an industrial process that involved the use of large quantities of elemental mercury. Past operations at the Y-12 Complex led to the release of mercury to the environment. Significant environmental media at the site were contaminated by accidental releases of mercury from the building process facilities piping and sumps associated with Y-12 Complex mercury handling facilities. Releases to the soil surrounding the buildings have resulted in significant levels of mercury in these areas of contamination, which is ultimately transported to UEFPC, its streambed, and off-site. Bechtel Jacobs Company LLC (BJC) is the DOE-Oak Ridge Operations prime contractor responsible for conducting environmental restoration activities at the Y-12 Complex. In order to mitigate the mercury being released to UEFPC, the Big Spring Water Treatment System will be designed and constructed as a Comprehensive Environmental Response, Compensation, and Liability Act action. This facility will treat the combined flow from Big Spring feeding Outfall 51 and the inflow now being processed at the East End Mercury Treatment System (EEMTS). Both discharge to UEFPC

Medicinal Plants.

ERIC Educational Resources Information Center

Phillipson, J. David

1997-01-01

Highlights the demand for medicinal plants as pharmaceuticals and the demand for health care treatments worldwide and the issues that arise from this. Discusses new drugs from plants, anticancer drugs, antiviral drugs, antimalarial drugs, herbal remedies, quality, safety, efficacy, and conservation of plants. Contains 30 references. (JRH)

Gassing in Li4Ti5O12-based batteries and its remedy

PubMed Central

He, Yan-Bing; Li, Baohua; Liu, Ming; Zhang, Chen; Lv, Wei; Yang, Cheng; Li, Jia; Du, Hongda; Zhang, Biao; Yang, Quan-Hong; Kim, Jang-Kyo; Kang, Feiyu

2012-01-01

Destructive gas generation with associated swelling has been a major challenge to the large-scale application of lithium ion batteries (LIBs) made from Li4Ti5O12 (LTO) anodes. Here we report root causes of the gassing behavior, and suggest remedy to suppress it. The generated gases mainly contain H2, CO2 and CO, which originate from interfacial reactions between LTO and surrounding alkyl carbonate solvents. The reactions occur at the very thin outermost surface of LTO (111) plane, which result in transformation from (111) to (222) plane and formation of (101) plane of anatase TiO2. A nanoscale carbon coating along with a stable solid electrolyte interface (SEI) film around LTO is seen most effective as a barrier layer in suppressing the interfacial reaction and resulting gassing from the LTO surface. Such an ability to tune the interface nanostructure of electrodes has practical implications in the design of next-generation high power LIBs. PMID:23209873

Technology needs for environmental restoration remedial action

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, J.S.

1992-11-01

This report summarizes the current view of the most important technology needs for the US Department of Energy (DOE) facilities operated by Martin Marietta Energy Systems, Inc. These facilities are the Oak Ridge National Laboratory, the Oak Ridge K-25 Site, the Oak Ridge Y-12 Plant, the Paducah Gaseous Diffusion Plant, and the Portsmouth Gaseous Diffusion Plant. The sources of information used in this assessment were a survey of selected representatives of the Environmental Restoration (ER) programs at each facility, results from a questionnaire distributed by Geotech CWM, Inc., for DOE, and associated discussions with individuals from each facility. This ismore » not a final assessment, but a brief look at an ongoing assessment; the needs will change as the plans for restoration change and, it is hoped, as some technical problems are solved through successful development programs.« less

Remediation mechanisms for Cd-contaminated soil using natural sepiolite at the field scale.

PubMed

Yin, Xiuling; Xu, Yingming; Huang, Rong; Huang, Qingqing; Xie, Zhonglei; Cai, Yanming; Liang, Xuefeng

2017-12-13

Remediation of heavy metal polluted agricultural soil is essential for human health and ecological safety and remediation mechanisms at the microscopic level are vital for their large-scale utilization. In this study, natural sepiolite was employed as an immobilization agent for in situ field-scale remediation of Cd-contaminated paddy soil and the remediation mechanisms were investigated in terms of soil chemistry and plant physiology. Natural sepiolite had a significant immobilization effect for bioavailable Cd contents in paddy soil, and consequently could lower the Cd concentrations of brown rice, husk, straw, and roots of rice plants by 54.7-73.7%, 44.0-62.5%, 26.5-67.2%, and 36.7-46.7%, respectively. Regarding soil chemistry, natural sepiolite increased the soil pH values and shifted the zeta potentials of soil particles to be more negative, enhancing the fixation or sorption of Cd on soil particles, and resulted in the reduction of HCl and DTPA extractable Cd concentrations in paddy soil. Natural sepiolite neither enhanced nor inhibited iron plaques on the rice root surface, but did change the chemical environments of Fe and S in rice root. Natural sepiolite improved the activities of antioxidant enzymes and enhanced the total antioxidant capacity to alleviate the stress of Cd. It also promotes the synthesis of GSH and NPT to complete the detoxification. In general, the remediation mechanisms of natural sepiolite for the Cd pollutant in paddy soil could be summarized as the collective effects of soil chemistry and plant physiology.

Alternative Remedies

MedlinePlus

... is called complementary medicine . Alternative remedies can include herbal medicines, vitamins, and folk remedies. Safety and Side Effects People often feel more comfortable taking herbal remedies, thinking that because these products are "natural," ...

Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information

NASA Astrophysics Data System (ADS)

Paoletta, Silvia; Sabbadin, Davide; von Kügelgen, Ivar; Hinz, Sonja; Katritch, Vsevolod; Hoffmann, Kristina; Abdelrahman, Aliaa; Straßburger, Jens; Baqi, Younis; Zhao, Qiang; Stevens, Raymond C.; Moro, Stefano; Müller, Christa E.; Jacobson, Kenneth A.

2015-08-01

The G protein-coupled P2Y12 receptor (P2Y12R) is an important antithrombotic target and of great interest for pharmaceutical discovery. Its recently solved, highly divergent crystallographic structures in complex either with nucleotides (full or partial agonist) or with a nonnucleotide antagonist raise the question of which structure is more useful to understand ligand recognition. Therefore, we performed extensive molecular modeling studies based on these structures and mutagenesis, to predict the binding modes of major classes of P2Y12R ligands previously reported. Various nucleotide derivatives docked readily to the agonist-bound P2Y12R, but uncharged nucleotide-like antagonist ticagrelor required a hybrid receptor resembling the agonist-bound P2Y12R except for the top portion of TM6. Supervised molecular dynamics (SuMD) of ticagrelor binding indicated interactions with the extracellular regions of P2Y12R, defining possible meta-binding sites. Ureas, sulfonylureas, sulfonamides, anthraquinones and glutamic acid piperazines docked readily to the antagonist-bound P2Y12R. Docking dinucleotides at both agonist- and antagonist-bound structures suggested interactions with two P2Y12R pockets. Thus, our structure-based approach consistently rationalized the main structure-activity relationships within each ligand class, giving useful information for designing improved ligands.

The harm of petroleum-polluted soil and its remediation research

NASA Astrophysics Data System (ADS)

Wang, Shuguang; Xu, Yan; Lin, Zhaofeng; Zhang, Jishi; Norbu, Namkha; Liu, Wei

2017-08-01

Land resources are the foundation of human's survival and development, and it's one of the most valuable natural resources of each country. In view of the serious problems of petroleum pollution to soil caused during the exploration and development processes, this article based on a large number of literature researches, firstly discussed the compositions and properties of petroleum contaminants, secondly investigated some restoration methods for the current situation of petroleum polluted soil, compared and analyzed the advantages and disadvantages of three kinds of bioremediation technologies. Finally, according to the deficiencies of previous research and existing problems, made an outlook of the physical and chemical remediation, bioremediation, and microbe-plant remediation, to provide some enlightenments for petroleum-contaminated soil remediation.

Crystallization Behavior of A Bulk Amorphous Mg62Cu26Y12 Alloy

NASA Astrophysics Data System (ADS)

Wu, Shyue-Sheng; Chin, Tsung-Shune; Su, Kuo-Chang

1994-07-01

The crystallization temperature, the associated activation energy and the crystallized structure of a bulk amorphous Mg62Cu26Y12 alloy with a diameter of 2.5 mm were studied. It possesses a one-step crystallization behavior. The crystallization reaction was found to be represented by: AM(MG62Cu26Y12)→Mg2Cu+MgY+CuY+Mg, ( Tx=188°C, Eac=134 kJ/mol) where AM represents the amorphous state, T x the crystallization temperature at an infinitesimal heating rate, and E ac the associated activation energy. The amount of crystalline phases were found to be Mg2Cu:MgY:CuY=76:17:7. The Mg phase is identifiable only by high resolution electron microscopy, not by X-ray diffraction. The crystallization leads to a sharp rise in electrical resistivity which is reversed to those of iron-based amorphous alloys.

Evaluation of Plant- Compost -Microorganisms Synergy for the Remediation of Diesel contaminated Soil: Success Stories from the Field Station

NASA Astrophysics Data System (ADS)

Hussain, Imran; Wimmer, Bernhard; Soja, Gerhard; Sessitsch, Angela; Reichenauer, Thomas G.

2016-04-01

Total petroleum hydrocarbons (TPH) contain a mixture of crude oil, gasoline, creosote and diesel is one of the most common groups of persistent organic pollutants. TPH enters into the ecosystem (soil, water and air) through leakage of underground storage tanks (LUST), accidental oil spills, transportation losses and industrial processes. Pollution associated with diesel oil and its refined products is of great concern worldwide due to its threats/damages for human and ecosystem health, soil structure and ground water quality. Extensive soils pollution with petroleum hydrocarbons results in extreme harsh surroundings, produce hydrophobic conditions and infertile soils that ultimately lead towards less plant and microorganisms growth. Among biological methods, bioremediation and phytoremediation are promising technologies that have both technical and ecological benefits as compared to convention methods. Within phytoremediation, rhizoremediation based on stimulation of degrading microorganism's population influenced by plant rhizospheric effect is known as main mechanism for phytoremediation of petroleum polluted soils. Composting along with rhizodegradtion was used to remediate freshly spilled soils at Lysimeter station Siebersdof, Austria. Experiment was started in July 2013 and will be monitored up to September 2016. Field station has 12 Lysimeter in total; each has length, width and depth of 100 cm respectively. Each Lysimeter was filled with normal agricultural soil from Siebersdof (0-70 cm), sand (70-85 cm) and stones (85-100cm). Sand and stones were added to support the normal leaching and percolation of water as we collected leachate samples after regular intervals. After filling, commercial diesel oil (2% w/w of 0-70 cm soil) was spilled on top of each Lysimeter as accidental spill occurs in filed. Compost was added at 0-15 cm layer (5% w/w of soil) to stimulate plant as well as microorganisms growth. Whole Lysimeter station was divided into three treatments

Arrestin Scaffolds NHERF1 to the P2Y12 Receptor to Regulate Receptor Internalization*

PubMed Central

Nisar, Shaista P.; Cunningham, Margaret; Saxena, Kunal; Pope, Robert J.; Kelly, Eamonn; Mundell, Stuart J.

2012-01-01

We have recently shown in a patient with mild bleeding that the PDZ-binding motif of the platelet G protein-coupled P2Y12 receptor (P2Y12R) is required for effective receptor traffic in human platelets. In this study we show for the first time that the PDZ motif-binding protein NHERF1 exerts a major role in potentiating G protein-coupled receptor (GPCR) internalization. NHERF1 interacts with the C-tail of the P2Y12R and unlike many other GPCRs, NHERF1 interaction is required for effective P2Y12R internalization. In vitro and prior to agonist stimulation P2Y12R/NHERF1 interaction requires the intact PDZ binding motif of this receptor. Interestingly on receptor stimulation NHERF1 no longer interacts directly with the receptor but instead binds to the receptor via the endocytic scaffolding protein arrestin. These findings suggest a novel model by which arrestin can serve as an adaptor to promote NHERF1 interaction with a GPCR to facilitate effective NHERF1-dependent receptor internalization. PMID:22610101

Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization.

PubMed

Nisar, Shaista P; Cunningham, Margaret; Saxena, Kunal; Pope, Robert J; Kelly, Eamonn; Mundell, Stuart J

2012-07-13

We have recently shown in a patient with mild bleeding that the PDZ-binding motif of the platelet G protein-coupled P2Y(12) receptor (P2Y(12)R) is required for effective receptor traffic in human platelets. In this study we show for the first time that the PDZ motif-binding protein NHERF1 exerts a major role in potentiating G protein-coupled receptor (GPCR) internalization. NHERF1 interacts with the C-tail of the P2Y(12)R and unlike many other GPCRs, NHERF1 interaction is required for effective P2Y(12)R internalization. In vitro and prior to agonist stimulation P2Y(12)R/NHERF1 interaction requires the intact PDZ binding motif of this receptor. Interestingly on receptor stimulation NHERF1 no longer interacts directly with the receptor but instead binds to the receptor via the endocytic scaffolding protein arrestin. These findings suggest a novel model by which arrestin can serve as an adaptor to promote NHERF1 interaction with a GPCR to facilitate effective NHERF1-dependent receptor internalization.

Superfund record of decision (EPA Region 6): Koppers (Texarkana plant), TX. (First remedial action), (amendment), March 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The 62-acre Koppers (Texarkana Plant) site is a former wood treatment facility located in Texarkana, Texas. From 1910 to 1961, the Koppers Company treated wood onsite using PCP, creosote, and metallic salts. After onsite operations ceased in 1961, the structures were removed and the property was sold for residential and industrial development. The 1992 ROD amendment appends the provisions of the mandate to the remedy, as established in the 1988 ROD. The primary contaminants of concern, as provided in the 1988 ROD, affecting the soil, sediment, debris, and ground water are VOCs, including benzene, toluene, and xylenes; other organics, includingmore » PAHs and PCP; and metals, including arsenic.« less

Recycled Uranium Mass Balance Project Y-12 National Security Complex Site Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2000-12-01

This report has been prepared to summarize the findings of the Y-12 National Security Complex (Y-12 Complex) Mass Balance Project and to support preparation of associated U. S. Department of Energy (DOE) site reports. The project was conducted in support of DOE efforts to assess the potential for health and environmental issues resulting from the presence of transuranic (TRU) elements and fission products in recycled uranium (RU) processed by DOE and its predecessor agencies. The United States government used uranium in fission reactors to produce plutonium and tritium for nuclear weapons production. Because uranium was considered scarce relative to demandmore » when these operations began almost 50 years ago, the spent fuel from U.S. fission reactors was processed to recover uranium for recycling. The estimated mass balance for highly enriched RU, which is of most concern for worker exposure and is the primary focus of this project, is summarized in a table. A discrepancy in the mass balance between receipts and shipments (plus inventory and waste) reflects an inability to precisely distinguish between RU and non-RU shipments and receipts involving the Y-12 Complex and Savannah River. Shipments of fresh fuel (non-RU) and sweetener (also non-RU) were made from the Y-12 Complex to Savannah River along with RU shipments. The only way to distinguish between these RU and non-RU streams using available records is by enrichment level. Shipments of {le}90% enrichment were assumed to be RU. Shipments of >90% enrichment were assumed to be non-RU fresh fuel or sweetener. This methodology using enrichment level to distinguish between RU and non-RU results in good estimates of RU flows that are reasonably consistent with Savannah River estimates. Although this is the best available means of distinguishing RU streams, this method does leave a difference of approximately 17.3 MTU between receipts and shipments. Slightly depleted RU streams received by the Y-12 Complex from

The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues.

PubMed

Quintas, Clara; Fraga, Sónia; Gonçalves, Jorge; Queiroz, Glória

2009-12-01

In the sympathetic nervous system, ATP is a co-transmitter and modulator of transmitter release, inhibiting noradrenaline release by acting on P2Y autoreceptors, but in peripheral tissues the subtypes involved have only scarcely been identified. We investigated the identity of the noradrenaline release-inhibiting P2Y subtypes in the epididymal portion of vas deferens and tail artery of the rat. The subtypes operating as autoreceptors, the signalling mechanism and cross-talk with alpha(2)-autoreceptors, was also investigated in the epididymal portion. In both tissues, the nucleotides 2-methylthioATP, 2-methylthioADP, ADP and ATP inhibited noradrenaline release up to 68%, with the following order of potency: 2-methylthioADP=2-methylthioATP>ADP=ATP in the epididymal portion and 2-methylthioADP=2-methylthioATP=ADP>ATP in the tail artery. The selective P2Y(1) antagonist 2'-deoxy-N(6)-methyladenosine 3',5'-bisphosphate (30microM) and the P2Y(12) antagonist 2,2-dimethyl-propionic acid 3-(2-chloro-6-methylaminopurin-9-yl)-2-(2,2-dimethyl-propionyloxymethyl)-propyl ester (30microM) increased noradrenaline release per se by 25+/-8% and 18+/-3%, respectively, in the epididymal portion but not in tail artery. Both antagonists attenuated the effect of nucleotides in the epididymal portion whereas in tail artery only the P2Y(1) antagonist was effective. The agonist of P2Y(1) and P2Y(12) receptors, 2-methylthioADP, caused an inhibition of noradrenaline release that was not prevented by inhibition of phospholipase C or protein kinase C but was abolished by pertussis toxin. 2-methylthioADP and the adenosine A(1) receptor agonist N(6)-cyclopentyladenosine were less potent at inhibiting noradrenaline release under marked influence of alpha(2)-autoinhibition. In both tissues, nucleotides modulate noradrenaline release by activation of inhibitory P2Y(1) receptors but in the epididymal portion P2Y(12) receptors also participate. P2Y(1) and P2Y(12) receptors are coupled to G

12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

Superfund Record of Decision (EPA Region 4): Milan Army Ammunition Plant, TN. (First remedial action), September 1992. Interim report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-09-30

The 22,436-acre Milan Army Ammunition Plant (MAAP) is located in western Tennessee, 5 miles east of Milan, Tennessee. The facility was constructed in 1941 to produce and store fuses, boosters, and small- and large-caliber ammunition. The ROD addresses an interim remedy for the contaminated ground water beneath and immediately downgradient from the former ponds as OU1. The primary contaminants of concern affecting the ground water are VOCs, including carbon disulfide; other organics, including HMX, RDX, 2,4,6-TNT, 2,4-DNT, 2,6-DNT, 1,3-DNB, 1,3,5-trinitrobenzene, and nitrobenzene; and inorganics, including nitrate.

THERMAL REMEDIATION

EPA Science Inventory

Thermal remediation is being proposed by Region I for remediation of the overburden soil and groundwater at the Solvent Recovery Services New England Superfund site. This presentation at the public meeting will acquaint area residents with thermal remediation. The two types of ...

Sources and remediation techniques for mercury contaminated soil.

PubMed

Xu, Jingying; Bravo, Andrea Garcia; Lagerkvist, Anders; Bertilsson, Stefan; Sjöblom, Rolf; Kumpiene, Jurate

2015-01-01

Mercury (Hg) in soils has increased by a factor of 3 to 10 in recent times mainly due to combustion of fossil fuels combined with long-range atmospheric transport processes. Other sources as chlor-alkali plants, gold mining and cement production can also be significant, at least locally. This paper summarizes the natural and anthropogenic sources that have contributed to the increase of Hg concentration in soil and reviews major remediation techniques and their applications to control soil Hg contamination. The focus is on soil washing, stabilisation/solidification, thermal treatment and biological techniques; but also the factors that influence Hg mobilisation in soil and therefore are crucial for evaluating and optimizing remediation techniques are discussed. Further research on bioremediation is encouraged and future study should focus on the implementation of different remediation techniques under field conditions. Copyright © 2014 Elsevier Ltd. All rights reserved.

Thermal remediation alters soil properties - a review.

PubMed

O'Brien, Peter L; DeSutter, Thomas M; Casey, Francis X M; Khan, Eakalak; Wick, Abbey F

2018-01-15

Contaminated soils pose a risk to human and ecological health, and thermal remediation is an efficient and reliable way to reduce soil contaminant concentration in a range of situations. A primary benefit of thermal treatment is the speed at which remediation can occur, allowing the return of treated soils to a desired land use as quickly as possible. However, this treatment also alters many soil properties that affect the capacity of the soil to function. While extensive research addresses contaminant reduction, the range and magnitude of effects to soil properties have not been explored. Understanding the effects of thermal remediation on soil properties is vital to successful reclamation, as drastic effects may preclude certain post-treatment land uses. This review highlights thermal remediation studies that have quantified alterations to soil properties, and it supplements that information with laboratory heating studies to further elucidate the effects of thermal treatment of soil. Notably, both heating temperature and heating time affect i) soil organic matter; ii) soil texture and mineralogy; iii) soil pH; iv) plant available nutrients and heavy metals; v) soil biological communities; and iv) the ability of the soil to sustain vegetation. Broadly, increasing either temperature or time results in greater contaminant reduction efficiency, but it also causes more severe impacts to soil characteristics. Thus, project managers must balance the need for contaminant reduction with the deterioration of soil function for each specific remediation project. Copyright © 2017 Elsevier Ltd. All rights reserved.

12. VIEW OF THE ROCKY FLATS PLANT LOOKING WEST. AFTER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. VIEW OF THE ROCKY FLATS PLANT LOOKING WEST. AFTER 38 YEARS, WEAPONS PRODUCTION CEASED IN 1989. IN 1992, THE PLANT MISSION CHANGED FROM WEAPONS PRODUCTION TO ENVIRONMENTAL CLEAN UP AND RESTORATION. BY 1995, THE SITE HAD BEGUN TO BE DISMANTLED (6/27/95). - Rocky Flats Plant, Bounded by Indiana Street & Routes 93, 128 & 72, Golden, Jefferson County, CO

Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors.

PubMed

Chang, Hung; Yanachkov, Ivan B; Michelson, Alan D; Li, YouFu; Barnard, M R; Wright, George E; Frelinger, Andrew L

2010-02-01

Diadenosine 5',5'''-P(1),P(4)- tetraphosphate (Ap(4)A) is stored in platelet dense granules, but its effects on platelet function are not well understood. We examined the effects of Ap(4)A on platelet purinergic receptors P2Y(1), P2Y(12) and P2X(1). Flow cytometry was used to measure the effects of Ap(4)A in the presence or absence of ADP on: a) P2Y(12)-mediated decrease in intraplatelet phosphorylated vasodilator stimulated phosphoprotein (VASP), b) P2Y(1)-mediated increase in platelet cytosolic Ca(2+), and c) P2X(1)-mediated intraplatelet entry of extracellular Ca(2+). ADP-stimulated platelet shape change (P2Y(1)-mediated) and aggregation (P2Y(1)- and P2Y(12)-mediated) were measured optically. Ap(4)A inhibited 3 microM ADP-induced: a) platelet aggregation (IC(50) 9.8+/-2.8 microM), b) P2Y(1)-mediated shape change, c) P2Y(1)-mediated increase in platelet cytosolic Ca(2+) (IC(50) 40.8+/-12.3 microM), and d) P2Y(12)-mediated decrease in VASP phosphorylation (IC(50)>250 microM). In the absence of added ADP, Ap(4)A had agonist effects on platelet P2X(1) and P2Y(12), but not P2Y(1), receptors. Ap(4)A, a constituent of platelet dense granules, is a) an antagonist of platelet P2Y(1) and P2Y(12) receptors, where it inhibits the effects of ADP, and b) an agonist of platelet P2X(1) and P2Y(12) receptors. Copyright 2009 Elsevier Ltd. All rights reserved.

Agonist and Antagonist Effects of Diadenosine Tetraphosphate, a Platelet Dense Granule Constituent, on Platelet P2Y1, P2Y12 and P2X1 Receptors

PubMed Central

Chang, Hung; Yanachkov, Ivan B.; Michelson, Alan D.; Li, YouFu; Barnard, M.R.; Wright, George E.; Frelinger, Andrew L.

2010-01-01

Introduction Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is stored in platelet dense granules, but its effects on platelet function are not well understood. Methods and Results We examined the effects of Ap4A on platelet purinergic receptors P2Y1, P2Y12 and P2X1. Flow cytometry was used to measure the effects of Ap4A in the presence or absence of ADP on: a) P2Y12-mediated decrease in intraplatelet phosphorylated vasodilator stimulated phosphoprotein (VASP), b) P2Y1-mediated increase in platelet cytosolic Ca2+, and c) P2X1-mediated intraplatelet entry of extracellular Ca2+. ADP-stimulated platelet shape change (P2Y1-mediated) and aggregation (P2Y1- and P2Y12-mediated) were measured optically. Ap4A inhibited 3 µM ADP-induced: a) platelet aggregation (IC50 9.8 ± 2.8 µM), b) P2Y1-mediated shape change, c) P2Y1-mediated increase in platelet cytosolic Ca2+ (IC50 40.8 ± 12.3 µM), and d) P2Y12-mediated decrease in VASP phosphorylation (IC50 >250 µM). In the absence of added ADP, Ap4A had agonist effects on platelet P2X1 and P2Y12, but not P2Y1, receptors. Conclusion Ap4A, a constituent of platelet dense granules, is a) an antagonist of platelet P2Y1 and P2Y12 receptors, where it inhibits the effects of ADP, and b) an agonist of platelet P2X1 and P2Y12 receptors. PMID:19945153

Proposed modifications to the RCRA post-closure permit for the Upper East Fork Poplar Creek Hydrogeologic Regime at the U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-05-01

This report presents proposed modifications to the Resource Conservation and Recovery Act (RCRA) Post-Closure Permit (PCP) for the Upper East Fork Poplar Creek Hydrogeologic Regime (permit number TNHW-088, EPA ID No. TN3 89 009 0001). The modifications are proposed to: (1) revise the current text for two of the Permit Conditions included in Permit Section II - General Facility Conditions, and (2) update the PCP with revised versions of the Y-12 Plant Groundwater Protection Program (GWPP) technical field procedures included in several of the Permit Attachments. The updated field procedures and editorial revisions are Class 1 permit modifications, as specifiedmore » in Title 40, Code of Federal Regulations (CFR) {section}270.42; Appendix I - Classification of Permit Modifications. These modifications are summarized below.« less

Medicinal plants used in Northern Peru for reproductive problems and female health

PubMed Central

2010-01-01

Infections of the reproductive tract, complications after childbirth, and reproductive problems continue to be a major health challenge worldwide. An impressive number of plant species is traditionally used to remedy such afflictions, and some have been investigated for their efficacy with positive results. A total of 105 plant species belonging to 91 genera and 62 families were documented and identified as herbal remedies for reproductive problems in Northern Peru. Most species used were Asteraceae (9.52%), followed by Lamiaceae and Fabaceae (8.57% and 6.67%). The most important families are clearly represented very similarly to their overall importance in the local pharmacopoeia. The majority of herbal preparations for reproductive afflictions were prepared from the leaves of plants (22.72%), the whole plant (21.97%), and stems (21.21%), while other plant parts were used less frequently. More than 60% of the cases fresh plant material was used to prepare remedies. Over 70% of the remedies were applied orally, while the remaining ones were applied topically. Many remedies were prepared as mixtures of multiple ingredients. Little scientific evidence exists to prove the efficacy of the species employed as reproductive disorder remedies in Northern Peru. Only 34% of the plants found or their congeners have been studied at all for their medicinal properties. The information gained on frequently used traditional remedies might give some leads for future targets for further analysis in order to develop new drugs. PMID:21040536

Remediation of lead contaminated soil by biochar-supported nano-hydroxyapatite.

PubMed

Yang, Zhangmei; Fang, Zhanqiang; Zheng, Liuchun; Cheng, Wen; Tsang, Pokeung Eric; Fang, Jianzhang; Zhao, Dongye

2016-10-01

In this study, a high efficiency and low cost biochar-supported nano-hydroxyapatite (nHAP@BC) material was used in the remediation of lead (Pb)-contaminated soil. The remediation effect of nHAP@BC on Pb-contaminated soil was evaluated through batch experiments. The stability, bioaccessibility of Pb in the soil and the change in soil characteristics are discussed. Furthermore, the effects of the amendments on the growth of cabbage mustard seedlings and the accumulation of Pb were studied. The results showed that the immobilization rates of Pb in the soil were 71.9% and 56.8%, respectively, after a 28 day remediation using 8% nHAP and nHAP@BC materials, and the unit immobilization amount of nHAP@BC was 5.6 times that of nHAP, indicating that nHAP@BC can greatly reduce the cost of remediation of Pb in soil. After the nHAP@BC remediation, the residual fraction Pb increased by 61.4%, which greatly reduced the bioaccessibility of Pb in the soil. Moreover, nHAP@BC could effectively reduce the accumulation of Pb in plants by 31.4%. Overall, nHAP@BC can effectively remediate Pb-contaminated soil and accelerate the recovery of soil fertility. Copyright © 2016 Elsevier Inc. All rights reserved.

Integrated phytobial remediation for sustainable management of arsenic in soil and water.

PubMed

Roy, Madhumita; Giri, Ashok K; Dutta, Sourav; Mukherjee, Pritam

2015-02-01

Arsenic (As), cited as the most hazardous substance by the U.S. Agency for Toxic Substance and Disease Registry (ATSDR, 2005), is an ubiquitous metalloid which when ingested for prolonged periods cause extensive health effects leading to ultimate untimely death. Plants and microbes can help mitigate soil and groundwater As problem since they have evolved elaborate detoxification machineries against this toxic metalloid as a result of their coexistence with this since the origin of life on earth. Utilization of the phytoremediation and bioremediation potential of the plants and microbes, respectively, is now regarded as two innovative tools that encompass biology, geology, biotechnology and allied sciences with cutting edge applications for sustainable mitigation of As epidemic. Discovery of As hyperaccumulating plants that uptake and concentrate large amounts of this toxic metalloid in their shoots or roots offered new hope to As phytoremediation, solar power based nature's own green remediation. This review focuses on how phytoremediation and bioremediation can be merged together to form an integrated phytobial remediation which could synergistically achieve the goal of large scale removal of As from soil, sediment and groundwater and overcome the drawbacks of the either processes alone. The review also points to the feasibility of the introduction of transgenic plants and microbes that bring new hope for more efficient treatment of As. The review identifies one critical research gap on the importance of remediation of As contaminated groundwater not only for drinking purpose but also for irrigation purpose and stresses that more research should be conducted on the use of constructed wetland, one of the most suitable areas of application of phytobial remediation. Finally the review has narrowed down on different phytoinvestigation and phytodisposal methods, which constitute the most essential and the most difficult part of pilot scale and field scale applications

Investigation of Y6Mn23 and YMn12 intermetallic alloys under high hydrogen pressure

NASA Astrophysics Data System (ADS)

Filipek, S. M.; Sato, R.; Kuriyama, N.; Tanaka, H.; Takeichi, N.

2010-03-01

Among three intermetallic compounds existing in Y-Mn system the YMn2 and Y6Mn23 can easily form interstitial hydrides while for YMn12 existence of hydride has never been reported. At moderate hydrogen pressure YMn2 and Y6Mn23 transform into YMn2H4.5 and Y6Mn23H25 respectively. At high hydrogen pressure the YMn2 (C15 or C14 parent structure) forms a unique YMn2H6 (s.g. Fm3m) complex hydride of fluorite structure in which one Mn atom Mn(1) and Y randomly occupy the 8c sites while second manganese (Mn2) in position 4a forms complex anion with 6 hydrogen atoms located in positions 24e. Formation of YMn2H6 independently of the structure of parent phase (C14 or C15) as well as occupation of the same site (8c) by Y and Mn(1) atoms suggested that also Y6Mn23 and YMn12 could transform into YMn2H6 - type hydride in which suitable number of Y atoms will be substituted by Mn(1) in the 8c positions. This assumption was confirmed by exposing R6Mn23 and RMn12 to 1 GPa of hydrogen pressure at 1000C. Formation of (RxMn2-x)MnH6 (where x = 18/29 or 3/13 for R6Mn23 and RMn12 hydrides respectively) was confirmed by XRD. Hydrogen concentration in both R6Mn23 and RMn12 based hydrides reached H/Me = 2 thus value two times higher than in R6Mn23H25.

Identification of Determinants Required for Agonistic and Inverse Agonistic Ligand Properties at the ADP Receptor P2Y12

PubMed Central

Schmidt, Philipp; Ritscher, Lars; Dong, Elizabeth N.; Hermsdorf, Thomas; Cöster, Maxi; Wittkopf, Doreen; Meiler, Jens

2013-01-01

The ADP receptor P2Y12 belongs to the superfamily of G protein–coupled receptors (GPCRs), and its activation triggers platelet aggregation. Therefore, potent antagonists, such as clopidogrel, are of high clinical relevance in prophylaxis and treatment of thromboembolic events. P2Y12 displays an elevated basal activity in vitro, and as such, inverse agonists may be therapeutically beneficial compared with antagonists. Only a few inverse agonists of P2Y12 have been described. To expand this limited chemical space and improve understanding of structural determinants of inverse agonist-receptor interaction, this study screened a purine compound library for lead structures using wild-type (WT) human P2Y12 and 28 constitutively active mutants. Results showed that ATP and ATP derivatives are agonists at P2Y12. The potency at P2Y12 was 2-(methylthio)-ADP > 2-(methylthio)-ATP > ADP > ATP. Determinants required for agonistic ligand activity were identified. Molecular docking studies revealed a binding pocket for the ATP derivatives that is bordered by transmembrane helices 3, 5, 6, and 7 in human P2Y12, with Y105, E188, R256, Y259, and K280 playing a particularly important role in ligand interaction. N-Methyl-anthraniloyl modification at the 3′-OH of the 2′-deoxyribose leads to ligands (mant-deoxy-ATP [dATP], mant-deoxy-ADP) with inverse agonist activity. Inverse agonist activity of mant-dATP was found at the WT human P2Y12 and half of the constitutive active P2Y12 mutants. This study showed that, in addition to ADP and ATP, other ATP derivatives are not only ligands of P2Y12 but also agonists. Modification of the ribose within ATP can result in inverse activity of ATP-derived ligands. PMID:23093496

Remediation mechanisms of mercapto-grafted palygorskite for cadmium pollutant in paddy soil.

PubMed

Liang, Xuefeng; Qin, Xu; Huang, Qingqing; Huang, Rong; Yin, Xiuling; Cai, Yanming; Wang, Lin; Sun, Yuebing; Xu, Yingming

2017-10-01

The immobilization agent was the key factor that determined the success of remediation of heavy metal polluted soil. In this study, mercapto-grafted palygorskite (MP) as a novel and efficient immobilization agent was utilized for the remediation of Cd-polluted paddy soil in pot trials, and the remediation mechanisms were investigated in the aspect of soil chemistry and plant physiology with different rice cultivars as model plants. Mercapto-grafted palygorskite at applied doses of 0.1-0.3% could reduce Cd contents of brown rice and straws of different cultivars significantly. Both reduced DTPA-extractable Cd contents in rhizosphere and non-rhizosphere soil and decreasing Cd contents in iron plaques on rice root surfaces confirmed that MP was an efficient immobilization agent for Cd pollutant in paddy soil. In the aspect of soil chemistry, the pH values of rhizosphere and non-rhizosphere soils had no statistical changes in the MP treatment groups, but their zeta potentials decreased obviously, indicating that MP could enhance the fixation or sorption of Cd on soil compositions. In the aspect of antioxidant system, MP could increase POD activity of rice roots significantly to alleviate the stress of Cd to roots, and resulted in the decrease of T-AOC, SOD, and CAT activities of rice roots of the selected cultivars. MP had no inhabitation or enhancement effects on TSH of rice roots but enhance the contents of MTs and NPT to binding Cd to complete detoxification process. MP as a novel and efficient immobilization agent could complete the remediation effects through soil chemistry and plant physiological mechanisms.

An intact PDZ motif is essential for correct P2Y12 purinoceptor traffic in human platelets.

PubMed

Nisar, Shaista; Daly, Martina E; Federici, Augusto B; Artoni, Andrea; Mumford, Andrew D; Watson, Stephen P; Mundell, Stuart J

2011-11-17

The platelet P2Y(12) purinoceptor (P2Y(12)R), which plays a crucial role in hemostasis, undergoes internalization and subsequent recycling to maintain receptor responsiveness, processes that are essential for normal platelet function. Here, we observe that P2Y(12)R function is compromised after deletion or mutation of the 4 amino acids at the extreme C-terminus of this receptor (ETPM), a putative postsynaptic density 95/disc large/zonula occludens-1 (PDZ)-binding motif. In cell line models, removal of this sequence or mutation of one of its core residues (P341A), attenuates receptor internalization and receptor recycling back to the membrane, thereby blocking receptor resensitization. The physiologic significance of these findings in the regulation of platelet function is shown by identification of a patient with a heterozygous mutation in the PDZ binding sequence of their P2Y(12)R (P341A) that is associated with reduced expression of the P2Y(12)R on the cell surface. Importantly, platelets from this subject showed significantly compromised P2Y(12)R recycling, emphasizing the importance of the extreme C-terminus of this receptor to ensure correct receptor traffic.

DDE remediation and degradation.

PubMed

Thomas, John E; Ou, Li-Tse; All-Agely, Abid

2008-01-01

DDT and its metabolites, DDD and DDE, have been shown to be recalcitrant to degradation. The parent compound, DDT, was used extensively worldwide starting in 1939 and was banned in the United States in 1973. The daughter compound, DDE, may result from aerobic degradation, abiotic dehydrochlorination, or photochemical decomposition. DDE has also occurred as a contaminant in commercial-grade DDT. The p,p'-DDE isomer is more biologically active than the o,p-DDE, with a reported half-life of -5.7 years. However, when DDT was repeatedly applied to the soil, the DDE concentration may remain unchanged for more than 20 yr. Remediation of DDE-contaminated soil and water may be done by several techniques. Phytoremediation involves translocating DDT, DDD, and DDE from the soil into the plant, although some aquatic species (duckweed > elodea > parrot feather) can transform DDT into predominantly DDD with some DDE being formed. Of all the plants that can uptake DDE, Cucurbita pepo has been the most extensively studied, with translocation values approaching "hyperaccumulation" levels. Soil moisture, temperature, and plant density have all been documented as important factors in the uptake of DDE by Cucurbita pepo. Uptake may also be influenced positively by amendments such as biosurfactants, mycorrhizal inoculants, and low molecular weight organic acids (e.g., citric and oxalic acids). DDE microbial degradation by dehalogenases, dioxygenases, and hydrolases occurs under the proper conditions. Although several aerobic degradation pathways have been proposed, none has been fully verified. Very few aerobic pure cultures are capable of fully degrading DDE to CO2. Cometabolism of DDE by Pseudomonas sp., Alicaligens sp., and Terrabacter sp. grown on biphenyl has been reported; however, not all bacterial species that produce biphenyl dioxygenase degraded DDE. Arsenic and copper inhibit DDE degradation by aerobic microorganisms. Similarly, metal chelates such as EDTA inhibit the

Use of filler limestone and construction and demolition residues for remediating soils contaminated with heavy metals: an assessment by means of plant uptake.

NASA Astrophysics Data System (ADS)

Banegas, Ascension; Martinez-Sanchez, Maria Jose; Agudo, Ines; Perez-Sirvent, Carmen

2010-05-01

A greenhouse trial was carried out to evaluate the assimilation of heavy metals by three types of horticultural plants (lettuce, broccoli and alfalfa), different parts of which are destined for human and animal consumption (leaves, roots, fruits). The plants were cultivated in four types of soil, one uncontaminated (T1), one soil collected in the surrounding area of Sierra Minera (T2), the third being remediated with residues coming from demolition and construction activities (T3) and the four remediated with filler limestone (T4). To determine the metal content, soil samples were first ground to a fine powder using an agate ball mill. Fresh vegetable samples were separated into root and aboveground biomass and then lyophilized. The DTPA-extractable content was also determined to calculate the bioavailable amount of metal. Finally, the translocation factor (TF) and bioconcentration factor (BCF) were calculated. Arsenic levels were obtained by using atomic fluorescence spectrometry with an automated continuous flow hydride generation (HG-AFS) spectrometer and Cd, Pb and Zn was determined by electrothermal atomization atomic absorption spectrometry (ETAAS) or flame atomic absorption spectrometry (FAAS). Samples of the leached water were also obtained and analyzed. According to our results, the retention of the studied elements varies with the type of plant and is strongly decreased by the incorporation of filler limestone and/or construction and demolition residues to the soils. This practice represents a suitable way to reduce the risk posed to the biota by the presence of high levels of heavy metal in soil.

Gene-by-environment effect of house dust mite on purinergic receptor P2Y12 (P2RY12) and lung function in children with asthma.

PubMed

Bunyavanich, S; Boyce, J A; Raby, B A; Weiss, S T

2012-02-01

Distinct receptors likely exist for leukotriene (LT)E(4), a potent mediator of airway inflammation. Purinergic receptor P2Y12 is needed for LTE(4)-induced airways inflammation, and P2Y12 antagonism attenuates house dust mite-induced pulmonary eosinophilia in mice. Although experimental data support a role for P2Y12 in airway inflammation, its role in human asthma has never been studied. To test for association between variants in the P2Y12 gene (P2RY12) and lung function in human subjects with asthma, and to examine for gene-by-environment interaction with house dust mite exposure. Nineteen single nucleotide polymorphisms (SNPs) in P2RY12 were genotyped in 422 children with asthma and their parents (n = 1266). Using family based methods, we tested for associations between these SNPs and five lung function measures. We performed haplotype association analyses and tested for gene-by-environment interactions using house dust mite exposure. We used the false discovery rate to account for multiple comparisons. Five SNPs in P2RY12 were associated with multiple lung function measures (P-values 0.006–0.025). Haplotypes in P2RY12 were also associated with lung function (P-values 0.0055–0.046). House dust mite exposure modulated associations between P2RY12 and lung function, with minor allele homozygotes exposed to house dust mite demonstrating worse lung function than those unexposed (significant interaction P-values 0.0028–0.040). The P2RY12 variants were associated with lung function in a large family-based asthma cohort. House dust mite exposure caused significant gene-by-environment effects. Our findings add the first human evidence to experimental data supporting a role for P2Y12 in lung function. P2Y12 could represent a novel target for asthma treatment.

Innovative vitrification for soil remediation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jetta, N.W.; Patten, J.S.; Hart, J.G.

1995-12-01

The objective of this DOE demonstration program is to validate the performance and operation of the Vortec Cyclone Melting System (CMS{trademark}) for the processing of LLW contaminated soils found at DOE sites. This DOE vitrification demonstration project has successfully progressed through the first two phases. Phase 1 consisted of pilot scale testing with surrogate wastes and the conceptual design of a process plant operating at a generic DOE site. The objective of Phase 2, which is scheduled to be completed the end of FY 95, is to develop a definitive process plant design for the treatment of wastes at amore » specific DOE facility. During Phase 2, a site specific design was developed for the processing of LLW soils and muds containing TSCA organics and RCRA metal contaminants. Phase 3 will consist of a full scale demonstration at the DOE gaseous diffusion plant located in Paducah, KY. Several DOE sites were evaluated for potential application of the technology. Paducah was selected for the demonstration program because of their urgent waste remediation needs as well as their strong management and cost sharing financial support for the project. During Phase 2, the basic nitrification process design was modified to meet the specific needs of the new waste streams available at Paducah. The system design developed for Paducah has significantly enhanced the processing capabilities of the Vortec vitrification process. The overall system design now includes the capability to shred entire drums and drum packs containing mud, concrete, plastics and PCB`s as well as bulk waste materials. This enhanced processing capability will substantially expand the total DOE waste remediation applications of the technology.« less

Using phytotechnologies to remediate brownfields, landfills, and other urban areas

Treesearch

R.S. Zalesny Jr.; Jill Zalesny

2010-01-01

Urban areas requiring remedial work has prompted the use of phytotechnologies to improve water quality, soil health, and biodiversity, as well as to achieve sustainable social and economic goals. Phytotechnologies directly use plants to clean up contaminated groundwater, soil, and sediment.

Calendar Year 2007 Groundwater Monitoring Report, U.S. Department of Energy Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvado Environmental LLC

2008-12-01

This report contains the groundwater and surface water monitoring data that were obtained during calendar year (CY) 2007 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (hereafter referenced as Y-12) on the DOE Oak Ridge Reservation (ORR) in Oak Ridge, Tennessee. The CY 2007 monitoring data were obtained from wells, springs, and surface water sampling locations in three hydrogeologic regimes at Y-12 (Figure A.1). The Bear Creek Hydrogeologic Regime (Bear Creek Regime) encompasses a section of Bear Creek Valley (BCV) between the west end of Y-12 and the west end of the Bear Creek Watershed (directions aremore » in reference to the Y-12 grid system). The Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime) encompasses the Y-12 industrial facilities and support structures in BCV. The Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime) encompasses a section of Chestnut Ridge directly south of Y-12. Section 2 of this report provides background information pertinent to groundwater and surface water quality monitoring in each hydrogeologic regime, including the topography and bedrock geology, surface water drainage, groundwater system, and extent of groundwater contamination. The CY 2007 groundwater and surface water monitoring data in this report were obtained from sampling and analysis activities implemented under the Y-12 Groundwater Protection Program (GWPP) managed by BWXT Y-12, L.L.C. (BWXT), and from sampling and analysis activities implemented under several monitoring programs managed by Bechtel Jacobs Company LLC (BJC). In December 2007, the BWXT corporate name was changed to Babcock & Wilcox Technical Services Y-12, LLC (B&W Y-12), which is applied to personnel and organizations throughout CY 2007 for this report. Cooperative implementation of the monitoring programs directed by the Y-12 GWPP and BJC (i.e., coordinating sample collection and sharing data) ensures that the CY 2007 monitoring results fulfill

Groundwater Protection Program Management Plan For The U.S. Department Of Energy Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvado Environmental, LLC

2009-09-01

This document presents the Groundwater Protection Program (GWPP) management plan for the U.S. Department of Energy (DOE) Y-12 National Security Complex (hereafter referenced as Y-12). The Y-12 GWPP functions as the primary point-of-contact for groundwater-related issues at Y-12, provides stewardship of the extensive network of groundwater monitoring wells at Y-12, and serves as a resource for technical expertise, support, and historical data for groundwater-related activities at Y-12. These organizational functions each serve the primary programmatic purpose of the GWPP, which is to ensure that groundwater monitoring activities within areas under Y-12 administrative control provide representative data in compliance with themore » multiple purposes of applicable state and federal regulations, DOE orders, and the corporate policies of Babcock & Wilcox Technical Services Y-12 LLC (hereafter referenced as B&W Y-12), the Y-12 management and operations (M&O) contractor for DOE. B&W Y-12 is a new corporate name, assumed in January 2007, for the company formerly known as BWXT Y-12, L.L.C., hereafter referenced as BWXT. This GWPP management plan addresses the requirements of DOE Order 450.1A Environmental Protection Program (hereafter referenced as DOE O 450.1A), which emphasize a site-wide approach for groundwater protection at each DOE facility through implementation of groundwater surveillance monitoring. Additionally, this plan addresses the relevant and applicable GWPP elements and goals described in the DOE O 450.1A technical guidance documents issued in June 2004 (DOE 2004) and May 2005 (DOE 2005). This GWPP management plan is a 'living' document that is reviewed annually, revised and reissued every three years, and is formatted to provide for updating individual sections independent of the rest of the document. Section 2 includes a short description of the groundwater system at Y-12, the history of groundwater monitoring at Y-12 and the corresponding evolution of

Plant-based remedies for wolf bites and rituals against wolves in the Iberian Peninsula: Therapeutic opportunities and cultural values for the conservation of biocultural diversity.

PubMed

González, José A; Carvalho, Ana Maria; Vallejo, José Ramón; Amich, Francisco

2017-09-14

Combined approaches to local knowledge and folk plant use improve awareness and promote effective strategies for the conservation of significant biocultural patrimony. Moreover, the information reported might be the basis for further appropriate phytochemical and pharmacological research. Therefore we provide an insight into traditional herbal remedies and practices for healing bite injuries in humans and domestic animals caused by the Iberian wolf. Wolf bites are associated with inflammatory processes and rabies is a potential complication AIMS: This paper describes and summarises the medicinal-veterinary empirical and ritual uses of the Iberian flora for wolf injuries and reviews the ethnopharmacological data of specific plants that are already published. The Iberian wolf is a critically endangered subspecies of the grey wolf. Livestock attacks attributed to wolves are increasingly frequent in the Iberian Peninsula, resulting in serious social problems. Interesting strategies for Iberian wolf conservation might be related to traditional grazing practices that are deeply linked with empirical knowledge and local practices passed on by oral tradition, which are also vulnerable now. Based on documentary sources from the beginning of the twentieth century to the present, we systematically searched old monographs, regional documents, technical papers, project reports, as well as the international and national databases and the available scientific literature, without restrictions regarding the language of the publications consulted. A total of 39 remedies for healing wolf bite injuries in humans and domestic animals was reported, highlighting the medicinal use of 33 species of vascular plants, mostly wild herbs, belonging to 18 botanical families. The use of wood ashes was also reported. The number of use-reports found represents a very high number considering similar European studies. Leaves were the predominant plant part mentioned. Boiling plant materials in water

Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets.

PubMed

Bijak, Michal; Szelenberger, Rafal; Dziedzic, Angela; Saluk-Bijak, Joanna

2018-02-10

Adenosine diphosphate (ADP) is the major platelet agonist, which is important in the shape changes, stability, and growth of the thrombus. Platelet activation by ADP is associated with the G protein-coupled receptors P2Y1 and P2Y12. The pharmacologic blockade of the P2Y12 receptor significantly reduces the risk of peripheral artery disease, myocardial infarction, ischemic stroke, and vascular death. Recent studies demonstrated the inhibition of ADP-induced blood platelet activation by three major compounds of the flavonolignans group: silybin, silychristin, and silydianin. For this reason, the aim of the current work was to verify the effects of silybin, silychristin, and silydianin on ADP-induced physiological platelets responses, as well as mechanisms of P2Y12-dependent intracellular signal transduction. We evaluated the effect of tested flavonolignans on ADP-induced blood platelets' aggregation in platelet-rich plasma (PRP) (using light transmission aggregometry), adhesion to fibrinogen (using the static method), and the secretion of PF-4 (using the ELISA method). Additionally, using the double labeled flow cytometry method, we estimated platelet vasodilator-stimulated phosphoprotein (VASP) phosphorylation. We demonstrated a dose-dependent reduction of blood platelets' ability to perform ADP-induced aggregation, adhere to fibrinogen, and secrete PF-4 in samples treated with flavonolignans. Additionally, we observed that all of the tested flavonolignans were able to increase VASP phosphorylation in blood platelets samples, which is correlated with P2Y12 receptor inhibition. All of these analyses show that silychristin and silybin have the strongest inhibitory effect on blood platelet activation by ADP, while silydianin also inhibits the ADP pathway, but to a lesser extent. The results obtained in this study clearly demonstrate that silybin, silychristin, and silydianin have inhibitory properties against the P2Y12 receptor and block ADP-induced blood platelet

An intact PDZ motif is essential for correct P2Y12 purinoceptor traffic in human platelets

PubMed Central

Nisar, Shaista; Daly, Martina E.; Federici, Augusto B.; Artoni, Andrea; Mumford, Andrew D.; Watson, Stephen P.

2011-01-01

The platelet P2Y12 purinoceptor (P2Y12R), which plays a crucial role in hemostasis, undergoes internalization and subsequent recycling to maintain receptor responsiveness, processes that are essential for normal platelet function. Here, we observe that P2Y12R function is compromised after deletion or mutation of the 4 amino acids at the extreme C-terminus of this receptor (ETPM), a putative postsynaptic density 95/disc large/zonula occludens-1 (PDZ)–binding motif. In cell line models, removal of this sequence or mutation of one of its core residues (P341A), attenuates receptor internalization and receptor recycling back to the membrane, thereby blocking receptor resensitization. The physiologic significance of these findings in the regulation of platelet function is shown by identification of a patient with a heterozygous mutation in the PDZ binding sequence of their P2Y12R (P341A) that is associated with reduced expression of the P2Y12R on the cell surface. Importantly, platelets from this subject showed significantly compromised P2Y12R recycling, emphasizing the importance of the extreme C-terminus of this receptor to ensure correct receptor traffic. PMID:21937696

Development of a green remediation tool in Japan.

PubMed

Yasutaka, Tetsuo; Zhang, Hong; Murayama, Koki; Hama, Yoshihito; Tsukada, Yasuhisa; Furukawa, Yasuhide

2016-09-01

The green remediation assessment tool for Japan (GRATJ) presented in this study is a spreadsheet-based software package developed to facilitate comparisons of the environmental impacts associated with various countermeasures against contaminated soil in Japan. This tool uses a life-cycle assessment-based model to calculate inventory inputs/outputs throughout the activity life cycle during remediation. Processes of 14 remediation methods for heavy metal contamination and 12 for volatile organic compound contamination are built into the tool. This tool can evaluate 130 inventory inputs/outputs and easily integrate those inputs/outputs into 9 impact categories, 4 integrated endpoints, and 1 index. Comparative studies can be performed by entering basic data associated with a target site. The integrated results can be presented in a simpler and clearer manner than the results of an inventory analysis. As a case study, an arsenic-contaminated soil remediation site was examined using this tool. Results showed that the integrated environmental impacts were greater with onsite remediation methods than with offsite ones. Furthermore, the contributions of CO2 to global warming, SO2 to urban air pollution, and crude oil to resource consumption were greater than other inventory inputs/outputs. The GRATJ has the potential to improve green remediation and can serve as a valuable tool for decision makers and practitioners in selecting countermeasures in Japan. Copyright © 2016 Elsevier B.V. All rights reserved.

Remediation of Petroleum-Contaminated Soil and Simultaneous Recovery of Oil by Fast Pyrolysis.

PubMed

Li, De-Chang; Xu, Wan-Fei; Mu, Yang; Yu, Han-Qing; Jiang, Hong; Crittenden, John C

2018-05-01

Petroleum-contaminated soil (PCS) caused by the accidental release of crude oil into the environment, which occurs frequently during oil exploitation worldwide, needs efficient and cost-effective remediation. In this study, a fast pyrolysis technology was implemented to remediate the PCS and concurrently recover the oil. The remediation effect related to pyrolytic parameters, the recovery rate of oil and its possible formation pathway, and the physicochemical properties of the remediated PCS and its suitability for planting were systematically investigated. The results show that 50.9% carbon was recovered in oil, whose quality even exceeds that of crude oil. Both extractable total petroleum hydrocarbon (TPH) and water-soluble organic matter (SOM) in PCS were completely removed at 500 °C within 30 min. The remaining carbon in remediated PCS was determined to be in a stable and innocuous state, which has no adverse effect on wheat growth. On the basis of the systematically characterizations of initial PCS and pyrolytic products, a possible thermochemical mechanism was proposed which involves evaporation, cracking and polymerization. In addition, the energy consumption analysis and remediation effect of various PCSs indicate that fast pyrolysis is a viable and cost-effective method for PCS remediation.

Wild plants as tools for the remediation of abandoned mining sites with a high arsenic content

NASA Astrophysics Data System (ADS)

Martínez-Lopez, Salvadora; Martínez-Sanchez, MJose; Perez-Sirvent, Carmen; Martínez, Lucia B.; Bech, Jaume

2014-05-01

The aim of this study was to assess the environmental risk posed by arsenic when new vegetation types are introduced, analyzing the transfer of arsenic in different plant species that grow spontaneously in mining areas of SE Spain (Sierra Minera of Cartagena), and the contribution of such plants to the environmental risk represented by their ingestion by animals living in the same ecosystems. When dealing with remediation projects in zones affected by mining activities, the risk posed by the ingestion of the plants by fauna is often forgotten. To study the transfer to the trophic chain, two mammals, sheep and vole, were selected. The risk analysis was centered in the contribution of these natural plants to the ingestion calculated. For this study, 21 vegetal species naturally growing in the soils were collected from the Sierra Minera. The vegetal material studied is clearly associated with the Mediterranean Region (S.E. of Spain) and the plant species collected are endemisms and plants characteristic of the zone. Physico-chemical properties were obtained by means of the usual procedures. To determine the arsenic content, the soil samples and plant materials were digested in a microwave system and the arsenic concentration was determined using atomic fluorescence spectrometry with an automated continuous flow hydride generation system. A semiquantitative estimation of the mineralogical composition of the samples was made by X Ray Diffraction analysis. The soils were classified into three groups: Low (group 1) (7-35 mg/kg) medium (group 2) (35-327 mg/kg) and high (group 3) (> 327 mg/kg), according to their As content. The mineralogy and As content of the soils studied depends on the materials related with mining activity. The descriptive statistical analysis of the population of plants studied showed the As range in roots to be 0.31-150 mg/kg while leaf concentrations were lower (0.21-83.4 mg/kg). The potential risk of As entering the food chain through of the plant

Remediation strategies for historical mining and smelting sites.

PubMed

Dybowska, Agnieszka; Farago, Margaret; Valsami-Jones, Eugenia; Thornton, Iain

2006-01-01

The environmental, social and economic problems associated with abandoned mine sites are serious and global. Environmental damage arising from polluted waters and dispersal of contaminated waste is a feature characteristic of many old mines in North America, Australia, Europe and elsewhere. Today, because of the efficiency of mining operations and legal requirements in many countries for prevention of environmental damage from mining operations, the release of metals to the environment from modern mining is low. However, many mineralized areas that were extensively worked in the 18th and 19th centuries and left abandoned after mining had ceased, have left a legacy of metal contaminated land. Unlike organic chemicals and plastics, metals cannot be degraded chemically or biologically into non-toxic and environmentally neutral constituents. Thus sites contaminated with toxic metals present a particular challenge for remediation. Soil remediation has been the subject of a significant amount of research work in the past decade; this has resulted in a number of remediation options currently available or being developed. Remediation strategies for metal/metalloid contaminated historical mining sites are reviewed and summarized in this article. It focuses on the current applications of in situ remediation with the use of soil amendments (adsorption and precipitation based methods are discussed) and phytoremediation (in situ plant based technology for environmental clean up and restoration). These are promising alternative technologies to traditional options of excavation and ex situ treatment, offering an advantage of being non-invasive and low cost. In particular, they have been shown to be effective in remediation of mining and smelting contaminated sites, although the long-term durability of these treatments cannot be predicted.

Luminescent properties of Cr-doped (GdX, Y1-X)3Al5O12 infra-red scintillator crystals

NASA Astrophysics Data System (ADS)

Suzuki, Akira; Kurosawa, Shunsuke; Yamaji, Akihiro; Shoji, Yasuhiro; Pejchal, Jan; Kamada, Kei; Yokota, Yuui; Yoshikawa, Akira

2014-10-01

Cr-doped (GdX Y1-X)3Al5O12 (X = 0, 0.25, 0.50) crystals prepared by the micro-pulling down method were investigated to develop a infra-red scintillator for implantable patient dosimeter in radiation therapy. In order to evaluate their optical and scintillation performance, the following properties were measured: (i) transmittance between ultra-violet and near-infra red region, (ii) photoluminescence spectra under Xe-lamp excitation, and (iii) X-ray excited radio-luminescence spectra. Cr:Y3Al5O12 and Cr:(Gd0.25 Y0.75)3Al5O12 crystals showed increased transmittance of 80%, while Cr:(Gd0.50 Y0.50)3Al5O12 had a lower transmittance of 40% due to its polycrystalline structure. In addition, all the Cr:(GdX Y1-X)3Al5O12 crystals showed sharp scintillation luminescence peaks ascribed to Cr3+ d-d transitions. Therefore, these results suggested that Cr:Y3Al5O12 and Cr:(Gd0.25 Y0.75)3Al5O12 crystals can be candidate materials for the dosimeter use.

Calendar Year 2011 Groundwater Monitoring Report, U.S. Department of Energy Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvado Environmental LLC,

2012-12-01

This report contains the groundwater and surface water monitoring data that were obtained during calendar year (CY) 2011 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) on the DOE Oak Ridge Reservation (ORR) in Oak Ridge, Tennessee. The CY 2011 monitoring data were obtained from wells, springs, and surface water sampling locations in three hydrogeologic regimes at Y-12. The Bear Creek Hydrogeologic Regime (Bear Creek Regime) encompasses a section of Bear Creek Valley (BCV) between the west end of Y-12 and the west end of the Bear Creek Watershed (directions are in reference to the Y-12more » grid system). The Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime) encompasses the Y-12 industrial facilities and support structures in BCV. The Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime) encompasses a section of Chestnut Ridge directly south of Y-12. This report provides background information pertinent to groundwater and surface water quality monitoring in each hydrogeologic regime, including the topography and bedrock geology, surface water drainage, groundwater system, and known extent of groundwater contamination. The CY 2011 groundwater and surface water monitoring data in this report were obtained from sampling and analysis activities implemented under the Y-12 Groundwater Protection Program (GWPP) managed by Babcock & Wilcox Technical Services Y-12, LLC (B&W Y-12) and from sampling and analysis activities implemented under several monitoring programs managed by the DOE Environmental Management (EM) contractor responsible for environmental cleanup on the ORR. In August 2011, URS | CH2M Oak Ridge LLC (UCOR) replaced Bechtel Jacobs Company LLC (BJC) as the DOE EM contractor. For this report, BJC/UCOR will be referenced as the managing contractor for CY 2011. Cooperative implementation of the monitoring programs directed by the Y-12 GWPP and BJC/UCOR (i.e., coordinating sample collection and sharing data

Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.

PubMed

Jeong, Young-Hoon; Bliden, Kevin P; Antonino, Mark J; Park, Ki-Soo; Tantry, Udaya S; Gurbel, Paul A

2012-07-01

We analyzed the antiplatelet effects of different P2Y(12) receptor blockers with VerifyNow P2Y12 assay (VN-P2Y12) and light transmittance aggregometry (LTA). The point-of-care VN-P2Y12 has been used to assess the antiplatelet effects in clopidogrel-treated patients but has not been evaluated in detail in patients treated with ticagrelor. Patients were randomly assigned to either ticagrelor [180 mg loading/90 mg twice daily (n = 37)] or clopidogrel [600 mg loading/75 mg daily (n = 39)] on top of aspirin treatment, and platelet reactivity was measured serially during onset, maintenance, and offset phases. High on-treatment platelet reactivity (HPR) was defined as 5 and 20 μM adenosine diphosphate-induced maximal platelet aggregation ≥46% and ≥59%, respectively, and P2Y12 reaction units ≥235. Platelet function measured by VN-P2Y12 correlated well with LTA (.812 ≤ ρ ≤ .823, P < .001). VN-P2Y12 "BASE" values were consistent during administration of both agents. Calculated and reported percent inhibitions by VN-P2Y12 were similar (difference, -0.6%; 95% agreement limits, -22.9% to 21.6%). Platelet inhibition by VN-P2Y12 during clopidogrel and ticagrelor administrations was comparable to platelet inhibition by LTA. HPR determined by LTA and VN-P2Y12 were well matched, and the risk stratification between the two methods showed strong agreement after both therapies (κ > .7). The VerifyNow P2Y12 assay is effective in assessing the antiplatelet effects and in identifying HPR during clopidogrel or ticagrelor therapy. Copyright © 2012 Mosby, Inc. All rights reserved.

Remediation of metal-contaminated land for plant cultivation in the Arctic/subarctic region

NASA Astrophysics Data System (ADS)

Kikuchi, Ryunosuke; Gorbacheva, Tamara T.; Ferreira, Carla S.

2017-04-01

Hazardous activities and/or industries involve the use, storage or disposal of hazardous substances. These substances can sometimes contaminate the soil, which can remain contaminated for many years. The metals can have severe effects of on ecosystems. In the Arctic/subarctic regions, the Kola Peninsula (66-70°N and 28°30'-41°30'E) in Russia is one of the seriously polluted regions: close to the nickel-copper smelters, the deposition of metal pollutants has severely damaged the soil and ground vegetation, resulting in a desert area. An area of 10-15 km around the smelters on the Kola Peninsula is today dry sandy and stony ground. A great amount of financial aid is usually required to recover theland. Considering cost performance, a pilot-scale (4ha) field test was carried out to investigate how to apply municipal sewage sludge for rehabilitation of degraded land near the Ni-Cu smelter complex on the Kola Peninsula. The above-mentioned field test for soil rehabilitation was performed while smelting activities were going on; thus, the survey fields were suffering from pollution emitted by the metallurgical industry, and may continue to suffer in the future. After the composting of sewage sludge, the artificial substratum made from the compost was introduced to the test field for the polluted-land remediation, and then willows, birches and grasses were planted on the substratum. The following remarkable points in pollution load were observed between the background field and the rehabilitation test field (e.g. polluted land): (i) the annual precipitation amount of SO42- (5668 g/ha) in the rehabilitation test field was over 5 times greater than that in the background field; (ii) the Pb amount (1.5 g/ha) in the rehabilitation test field was 29 times greater than that in the background field; (iii) the Co amount (10.9 g/ha) in the rehabilitation test field was 54 times greater than that in the background field; (iv) the Cu amount (752 g/ha) in the rehabilitation field

Y-12 National Security Complex Biological Monitoring and Abatement Program 2007 Calendar Yeare Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peterson, M.J.; Greeley, M. S. Jr.; Morris, G. W.

2008-07-01

The National Pollutant Discharge Elimination System (NPDES) permit issued for the Oak Ridge Y-12 National Security Complex (Y-12 Complex) which became effective May 1, 2006, continued a requirement for a Biological Monitoring and Abatement Program (BMAP). The BMAP was originally developed in 1985 to demonstrate that the effluent limitations established for the Y-12 Complex protected the classified uses of the receiving stream (East Fork Poplar Creek: EFPC), in particular, the growth and propagation of aquatic life (Loar et al. 1989). The objectives of the current BMAP are similar, specifically to assess stream ecological conditions relative to regulatory limits and criteria,more » to assess ecological impacts as well as recovery in response to Y-12 operations, and to investigate the causes of continuing impacts. The BMAP consists of three tasks that reflect complementary approaches to evaluating the effects of the Y-12 Complex discharges on the biotic integrity of EFPC. These tasks include: (1) bioaccumulation monitoring, (2) benthic macroinvertebrate community monitoring, and (3) fish community monitoring. As required by the NPDES permit, the BMAP benthic macroinvertebrate community monitoring task includes studies to annually evaluate the receiving stream's biological integrity in comparison to TN Water Quality Criteria. BMAP monitoring is currently being conducted at five primary EFPC sites, although sites may be excluded or added depending upon the specific objectives of the various tasks. Criteria used in selecting the sites include: (1) location of sampling sites used in other studies, (2) known or suspected sources of downstream impacts, (3) proximity to U.S. Department of Energy (DOE) Oak Ridge Reservation (ORR) boundaries, (4) appropriate habitat distribution, and (5) access. The primary sampling sites include upper EFPC at kilometers (EFKs) 24.4 and 23.4 [upstream and downstream of Lake Reality (LR) respectively]; EFK 18.7 (also EFK 18.2 and 19

A review of traditional remedies of ciguatera fish poisoning in the Pacific.

PubMed

Kumar-Roiné, Shilpa; Taiana Darius, H; Matsui, Mariko; Fabre, Nicolas; Haddad, Mohamed; Chinain, Mireille; Pauillac, Serge; Laurent, Dominique

2011-07-01

Ciguatera fish poisoning (CFP) is an illness caused by eating tropical coral fish contaminated with ciguatoxins (CTXs). The clinical management of patients with CFP is generally supportive and symptomatic in nature as no antidote exists. Of the many drugs prescribed, several have been claimed to be efficient in small, uncontrolled studies, but the outcomes of treatments with these medicines are often contradictory. In New Caledonia, traditional remedies are commonly employed in the treatment of CFP and of the 90 plant species catalogued as useful in CFP, the most popular herbal remedy by far is a decoction prepared from the leaves of Heliotropium foertherianum Diane & Hilger (Boraginaceae). Other important plants used in the treatment of CFP include Euphorbia hirta L. (Euphorbiaceae) and Vitex L. sp. (Lamiaceae). This review focuses on the evidence for efficacy of these species and pharmacological studies which support their use. Other plants used in CFP and the conventional treatment of CFP are also discussed briefly. Copyright © 2011 John Wiley & Sons, Ltd.

Phytostabilization potential of ornamental plants grown in soil contaminated with cadmium.

PubMed

Zeng, Peng; Guo, Zhaohui; Cao, Xia; Xiao, Xiyuan; Liu, Yanan; Shi, Lei

2018-03-21

In a greenhouse experiment, five ornamental plants, Osmanthus fragrans (OF), Ligustrum vicaryi L. (LV), Cinnamomum camphora (CC), Loropetalum chinense var. rubrum (LC), and Euonymus japonicas cv. Aureo-mar (EJ), were studied for the ability to phytostabilization for Cd-contaminated soil. The results showed that these five ornamental plants can grow normally when the soil Cd content is less than 24.6 mg·kg -1 . Cd was mainly deposited in the roots of OF, LV, LC and EJ which have grown in Cd-contaminated soils, and the maximum Cd contents reached 15.76, 19.09, 20.59 and 32.91 mg·kg -1 , respectively. For CC, Cd was mainly distributed in the shoots and the maximum Cd content in stems and leaves were 12.5 and 10.71 mg·kg -1 , however, the total amount of Cd in stems and leaves was similar with the other ornamental plants. The enzymatic activities in Cd-contaminated soil were benefited from the five tested ornamental plants remediation. Soil urease and sucrase activities were improved, while dehydrogenase activity was depressed. Meanwhile, the soil microbial community was slightly influenced when soil Cd content is less than 24.6 mg·kg -1 under five ornamental plants remediation. The results further suggested that ornamental plants could be promising candidates for phytostabilization of Cd-contaminated soil.

Overview of Green and Sustainable Remediation for Soil and Groundwater Remediation - 12545

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simpkin, Thomas J.; Favara, Paul

2012-07-01

Making remediation efforts more 'sustainable' or 'green' is a topic of great interest in the remediation community. It has been spurred on by Executive Orders from the White House, as well as Department of Energy (DOE) sustainability plans. In private industry, it is motivated by corporate sustainability goals and corporate social responsibility. It has spawned new organizations, areas of discussion, tools and practices, and guidance documents around sustainable remediation or green remediation. Green remediation can be thought of as a subset of sustainable remediation and is mostly focused on reducing the environmental footprint of cleanup efforts. Sustainable remediation includes bothmore » social and economic considerations, in addition to environmental. Application of both green and sustainable remediation (GSR) may involve two primary activities. The first is to develop technologies and alternatives that are greener or more sustainable. This can also include making existing remediation approaches greener or more sustainable. The second is to include GSR criteria in the evaluation of remediation alternatives and strategies. In other words, to include these GSR criteria in the evaluation of alternatives in a feasibility study. In some cases, regulatory frameworks allow the flexibility to include GSR criteria into the evaluation process (e.g., state cleanup programs). In other cases, regulations allow less flexibility to include the evaluation of GSR criteria (e.g., Comprehensive Environmental Response Compensation, and Liability Act (CERCLA)). New regulatory guidance and tools will be required to include these criteria in typical feasibility studies. GSR provides a number of challenges for remediation professionals performing soil and groundwater remediation projects. Probably the most significant is just trying to stay on top of the ever changing landscape of products, tools, and guidance documents coming out of various groups, the US EPA, and states. However

Diagnosing plant problems

Treesearch

Cheryl A. Smith

2008-01-01

Diagnosing Christmas tree problems can be a challenge, requiring a basic knowledge of plant culture and physiology, the effect of environmental influences on plant health, and the ability to identify the possible causes of plant problems. Developing a solution or remedy to the problem depends on a proper diagnosis, a process that requires recognition of a problem and...

Y{sub 2}MoSe{sub 3}O{sub 12} and Y{sub 2}MoTe{sub 3}O{sub 12}: Solid-state synthesis, structure determination, and characterization of two new quaternary mixed metal oxides containing asymmetric coordination environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bang, Seong-eun; Pan, Zhi; Kim, Yeong Hun

Two new quaternary yttrium molybdenum selenium/tellurium oxides, Y{sub 2}MoSe{sub 3}O{sub 12} and Y{sub 2}MoTe{sub 3}O{sub 12} have been prepared by standard solid-state reactions using Y{sub 2}O{sub 3}, MoO{sub 3}, and SeO{sub 2} (or TeO{sub 2}) as reagents. Single-crystal X-ray diffraction was used to determine the crystal structures of the reported materials. Although both of the materials contain second-order Jahn–Teller (SOJT) distortive cations and are stoichiometrically similar, they reveal different structural features: while Y{sub 2}MoSe{sub 3}O{sub 12} shows a three-dimensional framework consisting of YO{sub 8}, MoO{sub 6}, and SeO{sub 3} groups, Y{sub 2}MoTe{sub 3}O{sub 12} exhibits a layered structure composed ofmore » YO{sub 8}, MoO{sub 4}, TeO{sub 3}, and TeO{sub 4} polyhedra. With the Mo{sup 6+} cations in Y{sub 2}MoSe{sub 3}O{sub 12}, a C{sub 3}-type intraoctahedral distortion toward a face is observed, in which the direction of the out-of-center distortion for Mo{sup 6+} is away from the oxide ligand linked to a Se{sup 4+} cation. The Se{sup 4+} and Te{sup 4+} cations in both materials are in asymmetric coordination environment attributed to the lone pairs. Elemental analyses, infrared spectroscopy, thermal analyses, intraoctahedral distortions, and dipole moment calculations for the compounds are also presented. - Graphical abstract: Y{sub 2}MoSe{sub 3}O{sub 12} reveals a three-dimensional framework consisting of YO{sub 8}, MoO{sub 6}, and SeO{sub 3} polyhedra, whereas Y{sub 2}MoTe{sub 3}O{sub 12} exhibits a layered structure composed of YO{sub 8}, MoO{sub 4}, TeO{sub 3}, and TeO{sub 4} groups. - Highlights: • Two new selenite and tellurite (Y{sub 2}MoQ{sub 3}O{sub 12}; Q=Se and Te) are synthesized. • Y{sub 2}MoQ{sub 3}O{sub 12} contain second-order Jahn–Teller distortive cations in asymmetric environments. • The intra-octahedral distortion of the Mo{sup 6+} is influenced by the Se{sup 4+}.« less

Designing biochars for in situ remediation of metal contaminated mine spoils

EPA Science Inventory

Biochar in conjunction with other soil amendments can be used for in situ remediation of metal-contaminated mine spoils for improved site phytostabilization. For successful phytostabilization to occur, biochar must improve mine spoil health with respect to plant rooting plus upt...

Designing biochars for in situ remediation of metal contaminated mine spoils.

EPA Science Inventory

Biochar in conjunction with other soil amendments can be used for in situ remediation of metal-contaminated mine spoils for improved site phytostabilization. For successful phytostabilization to occur, biochar must improve mine spoil health with respect to plant rooting plus upt...

Calendar Year 2009 Groundwater Monitoring Report, U.S. Department of Energy, Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvado Environmental LLC

2010-12-01

This report contains the groundwater and surface water monitoring data that were obtained during calendar year (CY) 2009 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (hereafter referenced as Y-12) on the DOE Oak Ridge Reservation (ORR) in Oak Ridge, Tennessee. The CY 2009 monitoring data were obtained from wells, springs, and surface water sampling locations in three hydrogeologic regimes at Y-12. The Bear Creek Hydrogeologic Regime (Bear Creek Regime) encompasses a section of Bear Creek Valley (BCV) between the west end of Y-12 and the west end of the Bear Creek Watershed (directions are in referencemore » to the Y-12 grid system). The Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime) encompasses the Y-12 industrial facilities and support structures in BCV. The Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime) encompasses a section of Chestnut Ridge directly south of Y-12. Section 2 of this report provides background information pertinent to groundwater and surface water quality monitoring in each hydrogeologic regime, including the topography and bedrock geology, surface water drainage, groundwater system, and extent of groundwater contamination. The CY 2009 groundwater and surface water monitoring data in this report were obtained from sampling and analysis activities implemented under the Y-12 Groundwater Protection Program (GWPP) managed by Babcock & Wilcox Technical Services Y-12, LLC (B&W Y-12) and from sampling and analysis activities implemented under several monitoring programs managed by Bechtel Jacobs Company LLC (BJC). Cooperative implementation of the monitoring programs directed by the Y-12 GWPP and BJC (i.e., coordinating sample collection and sharing data) ensures that the CY 2009 monitoring results fulfill requirements of all the applicable monitoring drivers with no duplication of sampling and analysis efforts. Section 3 of this report contains a summary of information regarding the

Y-12 Groundwater Protection Program Groundwater and Surface Water Sampling and Analysis Plan for Calendar Year 2005

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2004-09-30

This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2005 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) that will be managed by the Y-12 Groundwater Protection Program (GWPP). Groundwater and surface water monitoring performed by the GWPP during CY 2005 will be in accordance with DOE Order 540.1 requirements and the following goals: (1) to maintain surveillance of existing and potential groundwater contamination sources; (2) to provide for the early detection of groundwater contamination and determine the quality of groundwater and surface water where contaminantsmore » are most likely to migrate beyond the Oak Ridge Reservation property line; (3) to identify and characterize long-term trends in groundwater quality at Y-12; and (4) to provide data to support decisions concerning the management and protection of groundwater resources. Groundwater and surface water monitoring during CY 2005 will be performed primarily in three hydrogeologic regimes at Y-12: the Bear Creek Hydrogeologic Regime (Bear Creek Regime), the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime), and the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Bear Creek and East Fork regimes are located in Bear Creek Valley, and the Chestnut Ridge Regime is located south of Y-12 (Figure A.1). Additional surface water monitoring will be performed north of Pine Ridge, along the boundary of the Oak Ridge Reservation (Figure A.1). Modifications to the CY 2005 monitoring program may be necessary during implementation. Changes in programmatic requirements may alter the analytes specified for selected monitoring wells or may add or remove wells from the planned monitoring network. All modifications to the monitoring program will be approved by the Y-12 GWPP manager and documented as addenda to this sampling and analysis plan.« less

Applying multivariate analysis as decision tool for evaluating sediment-specific remediation strategies.

PubMed

Pedersen, Kristine B; Lejon, Tore; Jensen, Pernille E; Ottosen, Lisbeth M

2016-05-01

Multivariate methodology was employed for finding optimum remediation conditions for electrodialytic remediation of harbour sediment from an Arctic location in Norway. The parts of the experimental domain in which both sediment- and technology-specific remediation objectives were met were identified. Objectives targeted were removal of the sediment-specific pollutants Cu and Pb, while minimising the effect on the sediment matrix by limiting the removal of naturally occurring metals while maintaining low energy consumption. Two different cell designs for electrochemical remediation were tested and final concentrations of Cu and Pb were below background levels in large parts of the experimental domain when operating at low current densities (<0.12 mA/cm(2)). However, energy consumption, remediation times and the effect on naturally occurring metals were different for the 2- and 3-compartment cells. Copyright © 2016 Elsevier Ltd. All rights reserved.

Remediation of heavy metal contaminated soils by using Solanum nigrum: A review.

PubMed

Rehman, Muhammad Zia Ur; Rizwan, Muhammad; Ali, Shafaqat; Ok, Yong Sik; Ishaque, Wajid; Saifullah; Nawaz, Muhammad Farrakh; Akmal, Fatima; Waqar, Maqsooda

2017-09-01

Heavy metals are among the major environmental pollutants and the accumulation of these metals in soils is of great concern in agricultural production due to the toxic effects on crop growth and food quality. Phytoremediation is a promising technique which is being considered as an alternative and low-cost technology for the remediation of metal-contaminated soils. Solanum nigrum is widely studied for the remediation of heavy metal-contaminated soils owing to its ability for metal uptake and tolerance. S. nigrum can tolerate excess amount of certain metals through different mechanism including enhancing the activities of antioxidant enzymes and metal deposition in non-active parts of the plant. An overview of heavy metal uptake and tolerance in S. nigrum is given. Both endophytic and soil microorganisms can play a role in enhancing metal tolerance in S. nigrum. Additionally, optimization of soil management practices and exogenous application of amendments can also be used to enhance metal uptake and tolerance in this plant. The main objective of the present review is to highlight and discuss the recent progresses in using S. nigrum for remediation of metal contaminated soils. Copyright © 2017 Elsevier Inc. All rights reserved.

Reinventing Remedial Education

ERIC Educational Resources Information Center

Stuart, Reginald

2009-01-01

Remedial education, although widely used and disguised with other names, was rarely talked about for it could tarnish a school's reputation if widely discussed. Today, more and more colleges and universities are ditching the old stigma associated with remedial education, reinventing their remedial education and retention programs and, in the…

The Determination of Soil-plant Transfer Coefficients of Cesium-137 and Other Elements by γ-Ray Measurement and PIXE Analysis, for use in the Remediation of Fukushima

NASA Astrophysics Data System (ADS)

Ishii, K.; Fujita, A.; Toyama, S.; Terakawa, A.; Matsuyama, S.; Arai, H.; Osada, N.; Takyu, S.; Matsuyama, T.; Koshio, S.; Watanabe, K.; Ito, S.; Kasahara, K.

Edible wild plants growing in the area around the Fukushima Daiichi nuclear power plant remain contaminated. It is important to identify plants with low levels of contamination for the restoration of agriculture in the area. We collected specimens of 10 wild plant species growing in Iitate village which is one of the most highly contaminated areas and also sampled the soil beneath each plant. We measured the specific activity of 137Cs and the concentrations of Na, Mg, Al, Si, P, S, K, Ca, Fe, Zn, Rb and Sr in these samples using a germanium detector and PIXE analysis, respectively. We compared the soil-plant transfer coefficient of 137Cs with those of each element and determined their correlation with 137Cs. It was found that a low Sr transfer coefficient could be used to determine the plants with a low 137Cs transfer coefficient. We suggest that PIXE analysis is a useful analysis technique for agricultural remediation projects in highly contaminated areas around the Fukushima Daiichi nuclear power plant.

A Comparative Assessment of Zootherapeutic Remedies From Selected Areas in Albania, Italy, Spain and Nepal

PubMed Central

Quave, Cassandra Leah; Lohani, Usha; Verde, Alonso; Fajardo, José; Rivera, Diego; Obón, Concepción; Valdes, Arturo; Pieroni, Andrea

2011-01-01

Zootherapy is the treatment of human ailments with remedies derived from animals and their products. Despite its prevalence in traditional medical practices worldwide, research on this phenomenon has often been neglected in comparison to medicinal plant research. Interviews regarding zootherapeutic traditions were conducted with informants from Albania, Italy, Nepal and Spain. We identified 80 species used in zootherapeutic remedies, representing 4 phyla in the animal kingdom: Annelida, Arthropoda, Chordata, and Mollusca. Remedies were ranked by consensus indices. Our studies show that the selection of medicinal fauna is mediated by human subsistence patterns. Concepts of health and disease differ among our study sites in the Mediterranean and Asia, and these differences also play a substantive role in the selection and use of animal-based remedies. PMID:21625340

Development Of An In Situ Passive Sampler For The Detection And Remediation of Explosive Compounds

DTIC Science & Technology

2016-06-07

FINAL REPORT Development of an In Situ Passive Sampler for the Detection and Remediation of Explosive Compounds SERDP Project ER-2539 MAY 2016...DATES COVERED (From - To) 4/24/15 – 12/1/2016 4. TITLE AND SUBTITLE Development of an In Situ Passive Sampler for the Detection and Remediation of...SUBJECT TERMS Passive samplers, Ethylene vinyl acetate, EVA sampler, Munitions, Monitoring, Remediation , Marine, Sediments 16. SECURITY

Ethnoveterinary herbal remedies used by farmers in four north-eastern Swiss cantons (St. Gallen, Thurgau, Appenzell Innerrhoden and Appenzell Ausserrhoden)

PubMed Central

2014-01-01

Background Very few ethnoveterinary surveys have been conducted in central Europe. However, traditional knowledge on the use of medicinal plants might be an option for future concepts in treatment of livestock diseases. Therefore the aim of this study was to document and analyse the traditional knowledge and use of homemade herbal remedies for livestock by farmers in four Swiss cantons. Methods Research was conducted in 2012. Fifty farmers on 38 farms were interviewed with the aid of semistructured interviews. Detailed information about the plants used and their mode of preparation were documented as well as dosage, route of administration, category of use, origin of knowledge, frequency of use, and satisfaction with the treatment. Results In total, 490 homemade remedies were collected. Out of these, 315 homemade remedies contained only one plant species (homemade single species herbal remedies, HSHR), which are presented in this paper. Seventy six species from 44 botanical families were mentioned. The most HSHR were quoted for the families of Asteraceae, Polygonaceae and Urticaceae. The plant species with the highest number of HSHRs were Matricaria recutita L., Calendula officinalis L., Rumex obtusifolius L. and Urtica dioica L. For each HSHR, one to eight different applications were enumerated. A total of 428 applications were documented, the majority of which were used to treat cattle. The main applications were in treatment of skin afflictions and sores, followed by gastrointestinal disorders and metabolic dysfunctions. Topical administration was most frequently used, followed by oral administration. In nearly half of the cases the knowledge on preparing and using herbal remedies was from forefathers and relatives. More than one third of the applications were used more than ten times during the last five years, and in about sixty percent of the cases, the last application was during the last year preceding the interviews. Conclusions Traditional knowledge of

Ethnoveterinary herbal remedies used by farmers in four north-eastern Swiss cantons (St. Gallen, Thurgau, Appenzell Innerrhoden and Appenzell Ausserrhoden).

PubMed

Disler, Monika; Ivemeyer, Silvia; Hamburger, Matthias; Vogl, Christian R; Tesic, Anja; Klarer, Franziska; Meier, Beat; Walkenhorst, Michael

2014-03-31

Very few ethnoveterinary surveys have been conducted in central Europe. However, traditional knowledge on the use of medicinal plants might be an option for future concepts in treatment of livestock diseases. Therefore the aim of this study was to document and analyse the traditional knowledge and use of homemade herbal remedies for livestock by farmers in four Swiss cantons. Research was conducted in 2012. Fifty farmers on 38 farms were interviewed with the aid of semistructured interviews. Detailed information about the plants used and their mode of preparation were documented as well as dosage, route of administration, category of use, origin of knowledge, frequency of use, and satisfaction with the treatment. In total, 490 homemade remedies were collected. Out of these, 315 homemade remedies contained only one plant species (homemade single species herbal remedies, HSHR), which are presented in this paper. Seventy six species from 44 botanical families were mentioned. The most HSHR were quoted for the families of Asteraceae, Polygonaceae and Urticaceae. The plant species with the highest number of HSHRs were Matricaria recutita L., Calendula officinalis L., Rumex obtusifolius L. and Urtica dioica L. For each HSHR, one to eight different applications were enumerated. A total of 428 applications were documented, the majority of which were used to treat cattle. The main applications were in treatment of skin afflictions and sores, followed by gastrointestinal disorders and metabolic dysfunctions. Topical administration was most frequently used, followed by oral administration. In nearly half of the cases the knowledge on preparing and using herbal remedies was from forefathers and relatives. More than one third of the applications were used more than ten times during the last five years, and in about sixty percent of the cases, the last application was during the last year preceding the interviews. Traditional knowledge of farmers about the use of medicinal plants

An Evidence-Based Review on Wound Healing Herbal Remedies From Reports of Traditional Persian Medicine.

PubMed

Hosseinkhani, Ayda; Falahatzadeh, Maryam; Raoofi, Elahe; Zarshenas, Mohammad M

2016-06-20

Research on wound healing agents is a developing area in biomedical sciences. Traditional Persian medicine is one of holistic systems of medicine providing valuable information on natural remedies. To collect the evidences for wound-healing medicaments from traditional Persian medicine sources, 5 main pharmaceutical manuscripts in addition to related contemporary reports from Scopus, PubMed, and ScienceDirect were studied. The underlying mechanisms were also saved and discussed. Totally, 65 herbs used in traditional Persian medicine for their wound healing properties was identified. Related anti-inflammatory, antioxidant, antimicrobial, and wound-healing activities of those remedies were studied. Forty remedies had at least one of those properties and 10 of the filtered plants possessed all effects. The medicinal plants used in wound healing treatment in traditional Persian medicine could be a good topic for further in vivo and clinical research. This might lead to development of effective products for wound treatment. © The Author(s) 2016.

An Evidence-Based Review on Wound Healing Herbal Remedies From Reports of Traditional Persian Medicine

PubMed Central

Hosseinkhani, Ayda; Falahatzadeh, Maryam; Raoofi, Elahe; Zarshenas, Mohammad M.

2016-01-01

Research on wound healing agents is a developing area in biomedical sciences. Traditional Persian medicine is one of holistic systems of medicine providing valuable information on natural remedies. To collect the evidences for wound-healing medicaments from traditional Persian medicine sources, 5 main pharmaceutical manuscripts in addition to related contemporary reports from Scopus, PubMed, and ScienceDirect were studied. The underlying mechanisms were also saved and discussed. Totally, 65 herbs used in traditional Persian medicine for their wound healing properties was identified. Related anti-inflammatory, antioxidant, antimicrobial, and wound-healing activities of those remedies were studied. Forty remedies had at least one of those properties and 10 of the filtered plants possessed all effects. The medicinal plants used in wound healing treatment in traditional Persian medicine could be a good topic for further in vivo and clinical research. This might lead to development of effective products for wound treatment. PMID:27330012

32 CFR 505.12 - Privacy Act enforcement actions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 3 2013-07-01 2013-07-01 false Privacy Act enforcement actions. 505.12 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.12 Privacy Act enforcement actions. (a.... (1) Civil remedies. The DA is subject to civil remedies for violations of the Privacy Act. In...

32 CFR 505.12 - Privacy Act enforcement actions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Privacy Act enforcement actions. 505.12 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.12 Privacy Act enforcement actions. (a.... (1) Civil remedies. The DA is subject to civil remedies for violations of the Privacy Act. In...

32 CFR 505.12 - Privacy Act enforcement actions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Privacy Act enforcement actions. 505.12 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.12 Privacy Act enforcement actions. (a.... (1) Civil remedies. The DA is subject to civil remedies for violations of the Privacy Act. In...

32 CFR 505.12 - Privacy Act enforcement actions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Privacy Act enforcement actions. 505.12 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.12 Privacy Act enforcement actions. (a.... (1) Civil remedies. The DA is subject to civil remedies for violations of the Privacy Act. In...

Y-12 National Security Complex Biological Monitoring And Abatement Program 2008 Calendar Year Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peterson, M. J.; Greeley Jr., M. S.; Mathews, T. J.

2009-07-01

The National Pollutant Discharge Elimination System (NPDES) permit issued for the Oak Ridge Y-12 National Security Complex (Y-12 Complex) which became effective May 1, 2006, continued a requirement for a Biological Monitoring and Abatement Program (BMAP). The BMAP was originally developed in 1985 to demonstrate that the effluent limitations established for the Y-12 Complex protected the classified uses of the receiving stream (East Fork Poplar Creek: EFPC), in particular, the growth and propagation of aquatic life (Loar et al. 1989). The objectives of the current BMAP are similar, specifically to assess stream ecological conditions relative to regulatory limits and criteria,more » to assess ecological impacts as well as recovery in response to Y-12 operations, and to investigate the causes of continuing impacts. The BMAP consists of three tasks that reflect complementary approaches to evaluating the effects of the Y-12 Complex discharges on the biotic integrity of EFPC. These tasks include: (1) bioaccumulation monitoring, (2) benthic macroinvertebrate community monitoring, and (3) fish community monitoring. As required by the NPDES permit, the BMAP benthic macroinvertebrate community monitoring task includes studies to annually evaluate the receiving stream's biological integrity in comparison to TN Water Quality Criteria. BMAP monitoring is currently being conducted at five primary EFPC sites, although sites may be excluded or added depending upon the specific objectives of the various tasks. Criteria used in selecting the sites include: (1) location of sampling sites used in other studies, (2) known or suspected sources of downstream impacts, (3) proximity to U.S. Department of Energy (DOE) Oak Ridge Reservation (ORR) boundaries, (4) appropriate habitat distribution, and (5) access. The primary sampling sites include upper EFPC at kilometers (EFKs) 24.4 and 23.4 [upstream and downstream of Lake Reality (LR) respectively]; EFK 18.7 (also EFK 18.2 and 19

Groundwater nitrate remediation using plant-chip bioreactors under phosphorus-limited environment

NASA Astrophysics Data System (ADS)

Satake, Shunichi; Tang, Changyuan

2018-02-01

Groundwater denitrification bioreactors under limited phosphorus conditions were studied in column experiments using four types of plant-chips. When the phosphate-P concentration in the influent increased from 0.04 mg/L to 0.4 mg/L, the nitrate removal ratio increased from 61.6% to 86.1% in reed, from 7.2% to 12.6% in Japanese cedar, from 37.0% to 73.6% in Moso bamboo, and from 19.2% to 50.5% in Lithocarpus edulis. The carbon source of the denitrifiers' growth was indicated by the content of acid detergent soluble organic matter in the chips. Furthermore, according to the modified Michaelis-Menten-type equation proposed in the study, the denitrification rate was largely limited by the phosphate-P concentration in reed and L. eduilis, and by the dissolved organic carbon (DOC) in Japanese cedar. Denitrification in Moso bamboo was affected by both phosphate-P and DOC. Besides the DOC, phosphorus emerged as an important limiting element of denitrification in some bioreactor plant-chips.

78 FR 46889 - Endangered and Threatened Wildlife and Plants; 12-Month Finding and Candidate Removal for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-02

... Service concluded that a 2006 travel management plan for Peavine Mountain would benefit rare plant species... Native Plant Society (CNPS) rare plant rank of 1B.1 (seriously threatened in California with over 80...; 4500030113] RIN 1018-AZ12 Endangered and Threatened Wildlife and Plants; 12-Month Finding and Candidate...

Pilot plant experiences using physical and biological treatment steps for the remediation of groundwater from a former MGP site.

PubMed

Wirthensohn, T; Schoeberl, P; Ghosh, U; Fuchs, W

2009-04-15

The production of manufactured gas at a site in Vienna, Austria led to the contamination of soil and groundwater with various pollutants including PAHs, hydrocarbons, phenols, BTEX, and cyanide. The site needs to be remediated to alleviate potential impacts to the environment. The chosen remediation concept includes the excavation of the core contaminated site and the setup of a hydraulic barrier to protect the surrounding aquifer. The extracted groundwater will be treated on-site. To design the foreseen pump-and-treat system, a pilot-scale plant was built and operated for 6 months. The scope of the present study was to test the effectiveness of different process steps, which included an aerated sedimentation basin, a submerged fixed film reactor (SFFR), a multi-media filter, and an activated carbon filter. The hydraulic retention time (HRT) was 7.0 h during normal flow conditions and 3.5h during high flow conditions. The treatment system was effective in reducing the various organic and inorganic pollutants in the pumped groundwater. However, it was also demonstrated that appropriate pre-treatment was essential to overcome problems with clogging due to precipitation of tar and sulfur compounds. The reduction of the typical contaminants, PAHs and BTEX, was more than 99.8%. All water quality parameters after treatment were below the Austrian legal requirements for discharge into public water bodies.

Toxicity of lanthanum oxide nanoparticles to the fungus Moniliella wahieum Y12T isolated from biodiesel.

PubMed

Zhang, Lin; Zhou, Lingyan; Li, Qing X; Liang, Hong; Qin, Huaming; Masutani, Stephen; Yoza, Brandon

2018-05-01

Moniliella wahieum Y12 T , isolated from biodiesel was used as a model organism to assess the use of lanthanum oxide (La 2 O 3 ) (60-80 nm) and silver oxide (AgO) (10-40 nm) nanoparticles as potential fungal inhibitors. This is the first study to investigate the use of nanoscale La 2 O 3 as a eukaryotic bio-inhibitor. The AgO nanoparticles were relatively effective at inhibiting the growth of M. wahieum Y12 T . The half maximal effective concentration (EC 50 ) for AgO was 0.012 mg/mL as compared with 4.63 mg/mL of La 2 O 3 . Fluorescein diacetate analysis showed that AgO nanoparticles significantly reduced metabolic activity in M. wahieum Y12 T . The results of this study indicated that AgO nanoparticles can be a nonspecific inhibitor for the treatment of M. wahieum Y12 T , a eukaryotic biodiesel contaminant. Copyright © 2018 Elsevier Ltd. All rights reserved.

Technology needs for environmental restoration remedial action. Environmental Restoration Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, J.S.

1992-11-01

This report summarizes the current view of the most important technology needs for the US Department of Energy (DOE) facilities operated by Martin Marietta Energy Systems, Inc. These facilities are the Oak Ridge National Laboratory, the Oak Ridge K-25 Site, the Oak Ridge Y-12 Plant, the Paducah Gaseous Diffusion Plant, and the Portsmouth Gaseous Diffusion Plant. The sources of information used in this assessment were a survey of selected representatives of the Environmental Restoration (ER) programs at each facility, results from a questionnaire distributed by Geotech CWM, Inc., for DOE, and associated discussions with individuals from each facility. This ismore » not a final assessment, but a brief look at an ongoing assessment; the needs will change as the plans for restoration change and, it is hoped, as some technical problems are solved through successful development programs.« less

Engineering Plant-Microbe Symbiosis for Rhizoremediation of Heavy Metals

PubMed Central

Wu, Cindy H.; Wood, Thomas K.; Mulchandani, Ashok; Chen, Wilfred

2006-01-01

The use of plants for rehabilitation of heavy-metal-contaminated environments is an emerging area of interest because it provides an ecologically sound and safe method for restoration and remediation. Although a number of plant species are capable of hyperaccumulation of heavy metals, the technology is not applicable for remediating sites with multiple contaminants. A clever solution is to combine the advantages of microbe-plant symbiosis within the plant rhizosphere into an effective cleanup technology. We demonstrated that expression of a metal-binding peptide (EC20) in a rhizobacterium, Pseudomonas putida 06909, not only improved cadmium binding but also alleviated the cellular toxicity of cadmium. More importantly, inoculation of sunflower roots with the engineered rhizobacterium resulted in a marked decrease in cadmium phytotoxicity and a 40% increase in cadmium accumulation in the plant root. Owing to the significantly improved growth characteristics of both the rhizobacterium and plant, the use of EC20-expressing P. putida endowed with organic-degrading capabilities may be a promising strategy to remediate mixed organic-metal-contaminated sites. PMID:16461658

Reducing the bioavailability of cadmium in contaminated soil by dithiocarbamate chitosan as a new remediation.

PubMed

Yin, Zheng; Cao, Jingjing; Li, Zhen; Qiu, Dong

2015-07-01

Dithiocarbamate chitosan (DTC-CTS) was used as a new amendment for remediation of cadmium (Cd)-contaminated soils to reduce the Cd bioavailability. Arabidopsis thaliana was chosen as a model plant to evaluate its efficiency. It was found that DTC-CTS could effectively improve the growth of A. thaliana. The amount of Cd up-taken by A. thaliana could be decreased by as much as 50% compared with that grown in untreated Cd-contaminated soil samples. The chlorophyll content and the aerial biomass of Arabidopsis also increased substantially and eventually returned to a level comparable to plants grown in non-contaminated soils, with the addition of DTC-CTS. These findings suggested that DTC-CTS amendment could be effective in immobilizing Cd and mitigating its accumulation in plants grown in Cd-contaminated soils, with potential application as an in situ remediation of Cd-polluted soils.

Superfund Record of Decision (EPA Region 5): New Brighton/Arden Hills (TCAAP), Twin Cities Army Ammunition Plant, MN. (Seventh remedial action), August 1989

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-08-11

The New Brighton/Arden Hills site, also known as the Twin Cities Army Ammunition Plant (TCAAP) site, is in New Brighton, Minnesota. Past disposal of ammunition manufacturing wastes onsite resulted in contamination of ground water beneath and downgradient of the site. A total of 14 waste-disposal locations have been identified and assigned as Sites A through K. During remedial investigations at Site D, soil was discovered to be contaminated with PCBs and other organic and metal contaminants. A soil-gas extraction system was implemented to remove the source of volatile organic contamination and reduce the potential of migration to ground water. Inmore » implementing the soil gas extraction system, PCB-contaminated soil was removed, stockpiled near Site D, and sealed with a plastic-liner material. The interim remedy addresses the treatment and disposal of contaminated soil that is stockpiled near Site D. The primary contaminants of concern affecting the soil are VOCs including TCE and PCE, other organics including PCBs, and metals including arsenic and lead.« less

A 1,000-Year-Old Antimicrobial Remedy with Antistaphylococcal Activity

PubMed Central

Roberts, Aled E. L.; Gabrilska, Rebecca; Rumbaugh, Kendra P.; Lee, Christina

2015-01-01

ABSTRACT Plant-derived compounds and other natural substances are a rich potential source of compounds that kill or attenuate pathogens that are resistant to current antibiotics. Medieval societies used a range of these natural substances to treat conditions clearly recognizable to the modern eye as microbial infections, and there has been much debate over the likely efficacy of these treatments. Our interdisciplinary team, comprising researchers from both sciences and humanities, identified and reconstructed a potential remedy for Staphylococcus aureus infection from a 10th century Anglo-Saxon leechbook. The remedy repeatedly killed established S. aureus biofilms in an in vitro model of soft tissue infection and killed methicillin-resistant S. aureus (MRSA) in a mouse chronic wound model. While the remedy contained several ingredients that are individually known to have some antibacterial activity, full efficacy required the combined action of several ingredients, highlighting the scholarship of premodern doctors and the potential of ancient texts as a source of new antimicrobial agents. PMID:26265721

An examination of antibacterial and antifungal properties of constituents described in traditional Ulster cures and remedies

PubMed Central

Woods-Panzaru, Simon; Nelson, David; McCollum, Graham; Ballard, Linda M; Millar, B Cherie; Maeda, Yasunori; Goldsmith, Colin E; Rooney, Paul J; Loughrey, Anne; Rao, Juluri R; Moore, John E

2009-01-01

Traditional herbal cures and remedies have played an important historical role in the treatment of a variety of illnesses and diseases in Northern Ireland for the last three hundred years. Recently, these have been reviewed in the publication by Linda Ballard from the Ulster Folk and Transport Museum at Cultra, Co. Down, which details the variety of local plants used and for what purpose. From this publication and another related publication, we note the description of several plant species that consistently appear in traditional cures and remedies, particularly used to treat infections and infectious diseases. Unfortunately, although these plants have strong associations with the local historical evidence base, there are very limited and mainly no formal publications in the medical/scientific evidence base, examining their scientific background and clinical efficacy. PMID:19252724

Remediation of Arsenic contaminated soil using malposed intercropping of Pteris vittata L. and maize.

PubMed

Ma, Jie; Lei, En; Lei, Mei; Liu, Yanhong; Chen, Tongbin

2018-03-01

Intercropping of arsenic (As) hyperaccumulator and cash crops during remediation of contaminated soil has been applied in farmland remediation project. However, little is known about the fate of As fractions in the soil profile and As uptake within the intercropping plants under field condition. In this study, As removal, uptake, and translocation were investigated within an intercropping system of Pteris vittata L. (P. vittata) and maize (Zea mays). Results indicated that the concentration of As associated with amorphous Fe (hydr)oxides in the 10-20 cm soil layer was significantly lower under malposed intercropping of P. vittata and maize, and As accumulation in P. vittata and biomass of P. vittata were simultaneously higher under malposed intercropping than under coordinate intercropping, leading to a 2.4 times higher rate of As removal. Although maize roots absorbed over 13.4 mg kg -1 As and maize leaves and flowers accumulated over 21.5 mg kg -1 As (translocation factor higher than 1), grains produced in all intercropping modes accumulated lower levels of As, satisfying the standard for human consumption. Our results suggested that malposed intercropping of a hyperaccumulator and a low-accumulation cash crop was an ideal planting pattern for As remediation in soil. Furthermore, timely harvest of P. vittata, agronomic strategies during remediation, and appropriate management of the above ground parts of P. vittata and high-As tissues of cash crops may further improve remediation efficiency. Copyright © 2017. Published by Elsevier Ltd.

Environmental Risks of Nano Zerovalent Iron for Arsenate Remediation: Impacts on Cytosolic Levels of Inorganic Phosphate and MgATP2- in Arabidopsis thaliana.

PubMed

Zhang, Weilan; Lo, Irene M C; Hu, Liming; Voon, Chia Pao; Lim, Boon Leong; Versaw, Wayne K

2018-04-03

The use of nano zerovalent iron (nZVI) for arsenate (As(V)) remediation has proven effective, but full-scale injection of nZVI into the subsurface has aroused serious concerns for associated environmental risks. This study evaluated the efficacy of nZVI treatment for arsenate remediation and its potential hazards to plants using Arabidopsis thaliana grown in a hydroponic system. Biosensors for inorganic phosphate (Pi) and MgATP 2- were used to monitor in vivo Pi and MgATP 2- levels in plant cells. The results showed that nZVI could remove As(V) from growth media, decrease As uptake by plants, and mitigate As(V) toxicity to plants. However, excess nZVI could cause Pi starvation in plants leading to detrimental effects on plant growth. Due to the competitive adsorption of As(V) and Pi on nZVI, removing As(V) via nZVI treatment at an upstream site could relieve downstream plants from As(V) toxicity and Pi deprivation, in which case 100 mg/L of nZVI was the optimal dosage for remediation of As(V) at a concentration around 16.13 mg/L.

In situ remediation and phytotoxicity assessment of lead-contaminated soil by biochar-supported nHAP.

PubMed

Yang, Zhangmei; Fang, Zhanqiang; Tsang, Pokeung Eric; Fang, Jianzhang; Zhao, Dongye

2016-11-01

In this study, a kind of biochar-supported nano-hydroxyapatite (nHAP@BC) material was used in in-situ remediation of lead-contaminated soil. Column experiments were performed to compare the mobility of nHAP@BC and Bare-nHAP. The immobilization, accumulation and toxic effects of Pb in the after-amended soil were assessed by the in vitro toxicity tests and pot experiments. The column experiments showed a significant improvement in the mobility of nHAP@BC. The immobilization rate of Pb in the soil was 74.8% after nHAP@BC remediation. Sequential extraction procedures revealed that the residual fraction of Pb increased by 66.6% after nHAP@BC remediation, which greatly reduced the bioavailability of Pb in the soil. In addition, pot experiments indicated that nHAP@BC could effectively reduce the upward translocation capacity of Pb in a soil-plant system. The concentration of Pb in the aerial part of the cabbage mustard was 0.1 mg/kg, which is lower than the tolerance limit (0.3 mg/kg). nHAP@BC can remediate Pb-contaminated soil effectively, which can restore soil quality for planting. Copyright © 2016 Elsevier Ltd. All rights reserved.

Medicinal plants popularly used in the Brazilian Tropical Atlantic Forest.

PubMed

Di Stasi, L C; Oliveira, G P; Carvalhaes, M A; Queiroz, M; Tien, O S; Kakinami, S H; Reis, M S

2002-02-01

A survey of medicinal plants used by rural and urban inhabitants of the three cities of the Tropical Atlantic Forest, Region of Vale do Ribeira, State of São Paulo, Brazil was performed by means of 200 interviews with medicinal plant users and extractors and, traditional healers. One hundred fourteen herbal remedies were recorded and the following information reported: Latin, vernacular and English names, plant part used, forms of preparation and application of the herbal remedies, medicinal or food uses, areas of plant collection, economic importance (when available) and other data.

Plant folk medicines for gastrointestinal disorders among the main tribes of Sonora, Mexico.

PubMed

Moreno-Salazar, S F; Robles-Zepeda, R E; Johnson, D E

2008-02-01

This paper describes the herbal remedies used by ethnic groups from Sonora, Mexico, for treatment of gastrointestinal diseases. Twelve types of these illnesses are cured using 85 different species which belong to 38 families. Thirty nine spp. are used to treat diarrhea, 28 for stomach-ache, 12 for constipation, 9 for intestinal parasites, 6 for indigestion, 3 for stomach or intestinal cancer, 3 for stomach inflammation and only 1 to treat gastrointestinal sicknesses, ulcers, gastritis, colitis and colic. Regarding the use of species of plant per ethnic group the following was observed: Mayo 47; Seri, 27; Yaqui, 13; Guarijio, 12, Pima, 5 and Papago, 3. The plants are used by two or more tribes, for the same or different illness but always related to the gastrointestinal system.

A shallow lake remediation regime with Phragmites australis: Incorporating nutrient removal and water evapotranspiration.

PubMed

Zhao, Ying; Yang, Zhifeng; Xia, Xinghui; Wang, Fei

2012-11-01

Shallow lake eutrophication has been an important issue of global water environment. Based on the simulation and field sampling experiments in Baiyangdian Lake, the largest shallow lake in North China, this study proposed a shallow lake remediation regime with Phragmites australis (reed) incorporating its opposite effects of nutrient removal and water evapotranspiration on water quality. The results of simulation experiments showed that both total nitrogen (TN) and phosphorus (TP) removal efficiencies increased with the increasing reed coverage. The TN removal efficiencies by reed aboveground uptake and rhizosphere denitrification were 11.2%, 13.8%, 22.6%, 28.4%, and 29.6% for the reed coverage of 20%, 40%, 60%, 80%, and 100%, respectively. Correspondingly, TP removal efficiencies by aboveground reed uptake were 1.4%, 2.5%, 4.4%, 7.4% and 7.9%, respectively. However, the water quality was best when the reed coverage was 60% (72 plants m(-2)). This was due to the fact that the concentration effect of reed evapotranspiration on nutrient increased with reed coverage. When the reed coverage was 100% (120 plants m(-2)), the evapotranspiration was approximately twice that without reeds. The field sampling results showed that the highest aboveground nutrient storages occurred in September. Thus, the proposed remediation regime for Baiyangdian Lake was that the reed coverage should be adjusted to 60%, and the aboveground biomass of reeds should be harvested in each September. With this remediation regime, TN and TP removal in Baiyangdian Lake were 117.8 and 4.0 g m(-2), respectively, and the corresponding removal efficiencies were estimated to be 49% and 8.5% after six years. This study suggests that reed is an effective plant for the remediation of shallow lake eutrophication, and its contrasting effects of nutrient removal and evapotranspiration on water quality should be considered for establishing the remediation regime in the future. Copyright © 2012 Elsevier

Novel Biochar-Plant Tandem Approach for Remediating Hexachlorobenzene Contaminated Soils: Proof-of-Concept and New Insight into the Rhizosphere.

PubMed

Song, Yang; Li, Yang; Zhang, Wei; Wang, Fang; Bian, Yongrong; Boughner, Lisa A; Jiang, Xin

2016-07-13

Volatilization of semi/volatile persistent organic pollutants (POPs) from soils is a major source of global POPs emission. This proof-of-concept study investigated a novel biochar-plant tandem approach to effectively immobilize and then degrade POPs in soils using hexachlorobenzene (HCB) as a model POP and ryegrass (Lolium perenne L.) as a model plant growing in soils amended with wheat straw biochar. HCB dissipation was significantly enhanced in the rhizosphere and near rhizosphere soils, with the greatest dissipation in the 2 mm near rhizosphere. This enhanced HCB dissipation likely resulted from (i) increased bioavailability of immobilized HCB and (ii) enhanced microbial activities, both of which were induced by ryegrass root exudates. As a major component of ryegrass root exudates, oxalic acid suppressed HCB sorption to biochar and stimulated HCB desorption from biochar and biochar-amended soils, thus increasing the bioavailability of HCB. High-throughput sequencing results revealed that the 2 mm near rhizosphere soil showed the lowest bacterial diversity due to the increased abundance of some genera (e.g., Azohydromonas, Pseudomonas, Fluviicola, and Sporocytophaga). These bacteria were likely responsible for the enhanced degradation of HCB as their abundance was exponentially correlated with HCB dissipation. The results from this study suggest that the biochar-plant tandem approach could be an effective strategy for remediating soils contaminated with semi/volatile organic contaminants.

Effectiveness of remediation of metal-contaminated mangrove sediments (Sydney estuary, Australia).

PubMed

Birch, Gavin; Nath, Bibhash; Chaudhuri, Punarbasu

2015-04-01

Industrial activities and urbanization have had a major consequence for estuarine ecosystem health and water quality globally. Likewise, Sydney estuary has been significantly impacted by widespread, poor industrial practices in the past, and remediation of legacy contaminants have been undertaken in limited parts of this waterway. The objective of the present investigation was to determine the effectiveness of remediation of a former Pb-contaminated industrial site in Homebush Bay on Sydney estuary (Australia) through sampling of inter-tidal sediments and mangrove (Avicennia marina) tissue (fine nutritive roots, pneumatophores, and leaves). Results indicate that since remediation 6 years previously, Pb and other metals (Cu, Ni and Zn) in surficial sediment have increased to concentrations that approach pre-remediation levels and that they were considerably higher than pre-settlement levels (3-30 times), as well as at the reference site. Most metals were compartmentalized in fine nutritive roots with bio-concentration factors greater than unity, while tissues of pneumatophores and leaves contained low metal concentrations. Lead concentrations in fine nutritive root, pneumatophore, and leaf tissue of mangroves from the remediated site were similar to trees in un-remediated sites of the estuary and were substantially higher than plants at the reference site. The situation for Zn in fine nutritive root tissue was similar. The source of the metals was either surface/subsurface water from the catchment or more likely remobilized contaminated sediment from un-remediated parts of Homebush Bay. Results of this study demonstrate the problems facing management in attempting to reduce contamination in small parts of a large impacted area to concentrations below local base level.

Immobilization and phytotoxicity of chromium in contaminated soil remediated by CMC-stabilized nZVI.

PubMed

Wang, Yu; Fang, Zhanqiang; Kang, Yuan; Tsang, Eric Pokeung

2014-06-30

The toxic effect of Cr(VI)-contaminated soil remediated by sodium carboxymethyl cellulose stabilized nanoscale zero-valent iron (CMC-stabilized nZVI) was assessed through in vitro toxicity and phytotoxicity tests. In vitro tests showed that 0.09 g L(-1) of Fe(0) nanoparticles (soil-to-solution ratio was 1 g:5 mL) significantly reduced the toxicity characteristic leaching procedure (TCLP) leachability and physiological based extraction test (PBET) bioaccessibility of Cr by 82% and 58%, respectively. Sequential extraction procedures (SEP) revealed that exchangeable (EX) Cr was completely converted to Fe-Mn oxides (OX) and organic matter (OM). Accordingly, phytotoxicity tests indicated that after 72-h remediation, Cr uptakes by edible rape and Chinese cabbage were suppressed by 61% and 36%, respectively. Moreover, no significant increase in Cr uptake was observed for either species after a 1-month static period for the amended soil. Regarding Fe absorption, germination and seedling growth, both plant species were significantly affected by CMC-nZVI-exposed soils. However, similar phytotoxicity tests conducted after 1 month showed an improvement in cultivation for both plants. Overall, this study demonstrated that CMC-nZVI could significantly enhance Cr immobilization, which reduced its leachability, bioavailability and bioaccumulation by plants. From a detoxification perspective, such remediation is technologically feasible and shows great potential in field applications. Copyright © 2014 Elsevier B.V. All rights reserved.

P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway.

PubMed

Li, Wei-Hua; Qiu, Ying; Zhang, Hong-Quan; Tian, Xin-Xia; Fang, Wei-Gang

2015-01-01

As one member of G protein-coupled P2Y receptors, P2Y2 receptor can be equally activated by extracellular ATP and UTP. Our previous studies have proved that activation of P2Y2 receptor by extracellular ATP could promote prostate cancer cell invasion and metastasis in vitro and in vivo via regulating the expressions of some epithelial-mesenchymal transition/invasion-related genes (including IL-8, E-cadherin, Snail and Claudin-1), and the most significant change in expression of IL-8 was observed after P2Y2 receptor activation. However, the signaling pathway downstream of P2Y2 receptor and the role of IL-8 in P2Y2-mediated prostate cancer cell invasion remain unclear. Here, we found that extracellular ATP/UTP induced activation of EGFR and ERK1/2. After knockdown of P2Y2 receptor, the ATP -stimulated phosphorylation of EGFR and ERK1/2 was significantly suppressed. Further experiments showed that inactivation of EGFR and ERK1/2 attenuated ATP-induced invasion and migration, and suppressed ATP-mediated IL-8 production. In addition, knockdown of IL-8 inhibited ATP-mediated invasion and migration of prostate cancer cells. These findings suggest that P2Y2 receptor and EGFR cooperate to upregulate IL-8 production via ERK1/2 pathway, thereby promoting prostate cancer cell invasion and migration. Thus blocking of the P2Y2-EGFR-ERK1/2 pathway may provide effective therapeutic interventions for prostate cancer.

Statistical trend analysis of groundwater data at Louisiana Army Ammunition Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhinge, D; Patel, J.; Skibinski, J.N.

1994-12-31

Statistical regression techniques were used to characterize temporal trends in groundwater monitoring data collected between 1980 and 1994 at Former Area P Lagoons, Louisiana Army Ammunition Plant (LAAP), a National Priorities List (NPL) site. Groundwater sampling data were evaluated for 12 wells (9 in the shallow aquifer and 3 in the deeper aquifer) and 9 contaminants of concern (COCs). A trend index (TI) was calculated from the sum of the number of improving and stable trends minus the number of deteriorating trends for each contaminant, each well, and the overall site. A positive TI indicates an improving trend for themore » site, contaminant, or well. Conversely, a negative TI indicates a deteriorating trend. The overall trend indices at the site for the shallow and deeper aquifers were found to be positive, indicating that the groundwater quality at Area P is generally improving. Interim remedial action was conducted at Area P from 1988 through 1990. The effect of remedial activities on groundwater quality was assessed by comparing the groundwater concentrations of nitro compounds measured immediately after the site remediation to those measured prior to the remedial action. The regression curves and the data indicated that a downward trend in the groundwater concentrations was observed immediately following the remediation activity at Area P. The trends from the regression analysis indicated that the overall remedy at Area P has been effective in reducing COC concentrations in groundwater.« less

Elemental composition of native wetland plants in constructed mesocosm treatment wetlands.

PubMed

Collins, Beverly S; Sharitz, Rebecca R; Coughlin, Daniel P

2005-05-01

Plants that accumulate a small percentage of metals in constructed treatment wetlands can contribute to remediation of acidic, metal contaminated runoff waters from coal mines or processing areas. We examined root and shoot concentrations of elements in four perennial wetland species over two seasons in mesocosm wetland systems designed to remediate water from a coal pile runoff basin. Deep wetlands in each system contained Myriophyllum aquaticum and Nymphaea odorata; shallow wetlands contained Juncus effusus and Pontederia cordata. Shoot elemental concentrations differed between plants of deep and shallow wetlands, with higher Zn, Al, and Fe concentrations in plants in shallow wetlands and higher Na, Mn, and P concentrations in plants in deep wetlands. Root and shoot concentrations of most elements differed between species in each wetland type. Over two seasons, these four common wetland plants did help remediate acidic, metal-contaminated runoff from a coal storage pile.

12. Interior view of cement and aggregate batch plant showing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Interior view of cement and aggregate batch plant showing storage bins. Photographer unknown, c. 1926. Source: Ralph Pleasant. - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

Optimal selection of biochars for remediating metals ...

EPA Pesticide Factsheets

Approximately 500,000 abandoned mines across the U.S. pose a considerable, pervasive risk to human health and the environment due to possible exposure to the residuals of heavy metal extraction. Historically, a variety of chemical and biological methods have been used to reduce the bioavailability of the metals at mine sites. Biochar with its potential to complex and immobilize heavy metals, is an emerging alternative for reducing bioavailability. Furthermore, biochar has been reported to improve soil conditions for plant growth and can be used for promoting the establishment of a soil-stabilizing native plant community to reduce offsite movement of metal-laden waste materials. Because biochar properties depend upon feedstock selection, pyrolysis production conditions, and activation procedures used, they can be designed to meet specific remediation needs. As a result biochar with specific properties can be produced to correspond to specific soil remediation situations. However, techniques are needed to optimally match biochar characteristics with metals contaminated soils to effectively reduce metal bioavailability. Here we present experimental results used to develop a generalized method for evaluating the ability of biochar to reduce metals in mine spoil soil from an abandoned Cu and Zn mine. Thirty-eight biochars were produced from approximately 20 different feedstocks and produced via slow pyrolysis or gasification, and were allowed to react with a f

Plants inside the leaf chamber of the LADA green house during Expedition 12

NASA Image and Video Library

2006-01-24

ISS012-E-15387 (24 Jan. 2006) --- A view of pea plants growing in the Lada greenhouse as a part of the Russian BIO-5 Rasteniya-2/Lada-2 (Plants-2) plant growth experiment located in the Zvezda Service Module photographed by an Expedition 12 crewmember on the International Space Station.

Soil contamination with cadmium, consequences and remediation using organic amendments.

PubMed

Khan, Muhammad Amjad; Khan, Sardar; Khan, Anwarzeb; Alam, Mehboob

2017-12-01

Cadmium (Cd) contamination of soil and food crops is a ubiquitous environmental problem that has resulted from uncontrolled industrialization, unsustainable urbanization and intensive agricultural practices. Being a toxic element, Cd poses high threats to soil quality, food safety, and human health. Land is the ultimate source of waste disposal and utilization therefore, Cd released from different sources (natural and anthropogenic), eventually reaches soil, and then subsequently bio-accumulates in food crops. The stabilization of Cd in contaminated soil using organic amendments is an environmentally friendly and cost effective technique used for remediation of moderate to high contaminated soil. Globally, substantial amounts of organic waste are generated every day that can be used as a source of nutrients, and also as conditioners to improve soil quality. This review paper focuses on the sources, generation, and use of different organic amendments to remediate Cd contaminated soil, discusses their effects on soil physical and chemical properties, Cd bioavailability, plant uptake, and human health risk. Moreover, it also provides an update of the most relevant findings about the application of organic amendments to remediate Cd contaminated soil and associated mechanisms. Finally, future research needs and directions for the remediation of Cd contaminated soil using organic amendments are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

Y-12 Groundwater Protection Program Groundwater and Surface Water Sampling and Analysis Plan for Calendar Year 2004

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvado Environmental LLC for the Environmental Compliance Department ES&H Division, Y-12 National Security Complex Oak Ridge, Tennessee

2003-09-30

This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2004 at the U.S. Department of Energy (DOE) Y-12 National Security Complex that will be managed by the Y-12 Groundwater Protection Program (GWPP). Groundwater and surface water monitoring performed by the GWPP during CY 2004 will be in accordance with the following requirements of DOE Order 5400.1: (1) to maintain surveillance of existing and potential groundwater contamination sources; (2) to provide for the early detection of groundwater contamination and determine the quality of groundwater and surface water where contaminants are mostmore » likely to migrate beyond the Oak Ridge Reservation property line; (3) to identify and characterize long-term trends in groundwater quality at Y-12; and (4) to provide data to support decisions concerning the management and protection of groundwater resources. Groundwater and surface water monitoring during CY 2004 will be performed primarily in three hydrogeologic regimes at Y-12: the Bear Creek Hydrogeologic Regime (Bear Creek Regime), the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime), and the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Bear Creek and East Fork regimes are located in Bear Creek Valley, and the Chestnut Ridge Regime is located south of Y-12 (Figure A.1). Additional surface water monitoring will be performed north of Pine Ridge, along the boundary of the Oak Ridge Reservation (Figure A.1). Modifications to the CY 2004 monitoring program may be necessary during implementation. Changes in programmatic requirements may alter the analytes specified for selected monitoring wells, or wells could be added or removed from the planned monitoring network. All modifications to the monitoring program will be approved by the Y-12 GWPP manager and documented as addenda to this sampling and analysis plan.« less

28 CFR 40.6 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Remedies. 40.6 Section 40.6 Judicial... Grievance Procedures § 40.6 Remedies. The grievance procedure shall afford a successful grievant a meaningful remedy. Although available remedies may vary among institutions, a reasonable range of meaningful...

28 CFR 40.6 - Remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Remedies. 40.6 Section 40.6 Judicial... Grievance Procedures § 40.6 Remedies. The grievance procedure shall afford a successful grievant a meaningful remedy. Although available remedies may vary among institutions, a reasonable range of meaningful...

Malaria in the Renaissance: remedies from European herbals from the 16th and 17th century.

PubMed

Adams, Michael; Alther, Wandana; Kessler, Michael; Kluge, Martin; Hamburger, Matthias

2011-01-27

From antiquity up into the 20th century tertian and quartan malaria which are caused by the parasites Plasmodium vivax and Plasmodium malariae were widespread in Central Europe. Hundreds of different remedies against malaria can be found in herbals from the Renaissance. To document and discuss from a modern pharmacological viewpoint the old remedies described in eight 16th and 17th century herbals written in German. Eight of the most important herbals of the 16th and 17th century including Bock (1577), Fuchs (1543), Matthiolus (1590), Lonicerus (1560), Brunfels (1532), Zwinger (1696), and Tabernaemontanus (1591 and 1678) were searched for terms related to malaria, and documented plants and recipes described for its treatment. Additionally the overlapping of these remedies with those in De Materia Medica by the Greek physician Dioscorides was studied. Three hundred and fourteen taxa were identified in the herbals for this indication. Recent pharmacological data was found for just 5% of them. The influence of De Materia Medica was shown to be negligible with only 3.5% of the remedies in common. European Renaissance herbals may be a valuable source of information for the selection of plants for focussed antiplasmodial screening programmes, but have received only little scientific attention. Antimalarial remedies from these herbals must be viewed as independent sources of knowledge separate from Dioscorides' De Materia Medica. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

P2Y12 shRNA treatment decreases SGC activation to relieve diabetic neuropathic pain in type 2 diabetes mellitus rats.

PubMed

Wang, Shouyu; Wang, Zilin; Li, Lin; Zou, Lifang; Gong, Yingxin; Jia, Tianyu; Zhao, Shanhong; Yuan, Huilong; Shi, Liran; Liu, Shuangmei; Wu, Bing; Yi, Zhihua; Liu, Hui; Gao, Yun; Li, Guilin; Deussing, Jan M; Li, Man; Zhang, Chunping; Liang, Shangdong

2018-06-26

Diabetic neuropathic pain is a common complication of type 2 diabetes mellitus (DM). Activation of satellite glial cells (SGCs) in the dorsal root ganglia (DRG) plays a crucial role in neuropathic pain through the release of proinflammatory cytokines. The P2Y12 receptor is expressed in SGCs of the DRG. In this study, our aim was to investigate the role of the P2Y12 receptor on the pathological changes in diabetic neuropathic pain. The present study showed that diabetic neuropathic pain increased mechanical and thermal hyperalgesia in type 2 DM model rats. The results showed that the expression levels of P2Y12 messenger RNA (mRNA) and protein in DRG SGCs were increased in DM model rats compared with control rats. Glial fibrillary acidic protein (GFAP) and interleukin-1β (IL-1β) expression levels in the DRG were increased in DM rats. Upregulation of GFAP is a marker of SGC activation. Targeting the P2Y12 receptor by short hairpin RNA (shRNA) decreased the upregulated expression of P2Y12 mRNA and protein, coexpression of P2Y12 and GFAP, the expression of GFAP, IL-1β, and tumor necrosis factor-receptor 1 in the DRG of DM rats, and relieved mechanical and thermal hyperalgesia in DM rats. After treatment with the P2Y12 receptor shRNA, the enhancing integrated OPTICAL density (IOD) ratios of p-P38 MAPK to P38 mitogen activated protein kinase (MAPK) in the DM rats treated with P2Y12 shRNA were significantly lower than that in the untreated DM rats. Therefore, P2Y12 shRNA treatment decreased SGC activation to relieve mechanical and thermal hyperalgesia in DM rats. © 2018 Wiley Periodicals, Inc.

Low altitude unmanned aerial vehicle for characterising remediation effectiveness following the FDNPP accident.

PubMed

Martin, P G; Payton, O D; Fardoulis, J S; Richards, D A; Yamashiki, Y; Scott, T B

2016-01-01

On the 12th of March 2011, The Great Tōhoku Earthquake occurred 70 km off the eastern coast of Japan, generating a large 14 m high tsunami. The ensuing catalogue of events over the succeeding 12 d resulted in the release of considerable quantities of radioactive material into the environment. Important to the large-scale remediation of the affected areas is the accurate and high spatial resolution characterisation of contamination, including the verification of decontaminated areas. To enable this, a low altitude unmanned aerial vehicle equipped with a lightweight gamma-spectrometer and height normalisation system was used to produce sub-meter resolution maps of contamination. This system provided a valuable method to examine both contaminated and remediated areas rapidly, whilst greatly reducing the dose received by the operator, typically in localities formerly inaccessible to ground-based survey methods. The characterisation of three sites within Fukushima Prefecture is presented; one remediated (and a site of much previous attention), one un-remediated and a third having been subjected to an alternative method to reduce emitted radiation dose. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor.

PubMed

Aungraheeta, Riyaad; Conibear, Alexandra; Butler, Mark; Kelly, Eamonn; Nylander, Sven; Mumford, Andrew; Mundell, Stuart J

2016-12-08

Ticagrelor is a potent antagonist of the P2Y 12 receptor (P2Y 12 R) and consequently an inhibitor of platelet activity effective in the treatment of atherothrombosis. Here, we sought to further characterize its molecular mechanism of action. Initial studies showed that ticagrelor promoted a greater inhibition of adenosine 5'-diphosphate (ADP)-induced Ca 2+ release in washed platelets vs other P2Y 12 R antagonists. This additional effect of ticagrelor beyond P2Y 12 R antagonism was in part as a consequence of ticagrelor inhibiting the equilibrative nucleoside transporter 1 (ENT1) on platelets, leading to accumulation of extracellular adenosine and activation of G s -coupled adenosine A 2A receptors. This contributed to an increase in basal cyclic adenosine monophosphate (cAMP) and vasodilator-stimulated phosphoprotein phosphorylation (VASP-P). In addition, ticagrelor increased platelet cAMP and VASP-P in the absence of ADP in an adenosine receptor-independent manner. We hypothesized that this increase originated from a direct effect on basal agonist-independent P2Y 12 R signaling, and this was validated in 1321N1 cells stably transfected with human P2Y 12 R. In these cells, ticagrelor blocked the constitutive agonist-independent activity of the P2Y 12 R, limiting basal G i -coupled signaling and thereby increasing cAMP levels. These data suggest that ticagrelor has the pharmacological profile of an inverse agonist. Based on our results showing insurmountable inhibition of ADP-induced Ca 2+ release and forskolin-induced cAMP, the mode of antagonism of ticagrelor also appears noncompetitive, at least functionally. In summary, our studies describe 2 novel modes of action of ticagrelor, inhibition of platelet ENT1 and inverse agonism at the P2Y 12 R that contribute to its effective inhibition of platelet activation. © 2016 by The American Society of Hematology.

Calendar Year 2004 Groundwater Monitoring Report, U.S. Department of Energy Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

N /A

2005-09-01

This report contains the groundwater and surface water monitoring data that were obtained during calendar year (CY) 2004 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (hereafter referenced as Y-12) on the DOE Oak Ridge Reservation (ORR) in Oak Ridge, Tennessee. The CY 2004 monitoring data were obtained from groundwater and surface water sampling locations in three hydrogeologic regimes at Y-12 (Figure A.1). The Bear Creek Hydrogeologic Regime (Bear Creek Regime) encompasses a section of Bear Creek Valley (BCV) between the west end of Y-12 and the west end of the Bear Creek Watershed (directions are inmore » reference to the Y-12 grid system). The Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime) encompasses the Y-12 industrial facilities and support structures in BCV. The Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime) encompasses a section of Chestnut Ridge south of Y-12. The CY 2004 monitoring data were obtained under the Y-12 Groundwater Protection Program (GWPP) managed by BWXT Y-12, L.L.C. (BWXT) and several monitoring programs managed by Bechtel Jacobs Company LLC (BJC). Data contained in this report meet applicable requirements of DOE Order 450.1 (Environmental Protection Program) regarding evaluation of groundwater and surface water quality in areas: (1) which are, or could be, affected by operations at Y-12 (surveillance monitoring); and (2) where contaminants from Y-12 are most likely to migrate beyond the boundaries of the ORR (exit pathway/perimeter monitoring). However, detailed analysis, evaluation, and interpretation of the CY 2004 monitoring data is deferred to the Y-12 Groundwater Protection Program Groundwater Monitoring Data Compendium (BWXT 2005). For each monitoring well, spring, and surface water sampling station included in this report, the GWPP Compendium provides: (1) pertinent well installation and construction information; (2) a complete sampling history, including sampling methods

Feasibility of Using Phytoextraction to Remediate a Compost-Based Soil Contaminated with Cadmium.

PubMed

Parisien, Michele A; Rutter, Allison; Zeeb, Barbara A

2015-01-01

Greenhouse and in-situ field experiments were used to determine the potential for phytoextraction to remediate soil contaminated with Cd from municipal solid waste (MSW) and sewage sludge (SS) compost application at a Peterborough (Canada) site. For the greenhouse experiment, one native (Chenopodium album) and three naturalized (Poa compressa, Brassica juncea, Helianthus annuus) plant species were planted in soil containing no detectable Cd (<1.0 μg·g(-1)), and soil from the site containing low (5.0 ± 0.3 μg·g(-1) Cd), and high (16.5 ± 1.2 μg⋅g(-1) Cd) Cd concentrations. Plant uptake was low (root BAFs ≤0.5) for all species except P. compressa in the low Cd treatment (BAF 1.0). Only B. juncea accumulated Cd in its shoots, though uptake was low (BAF ≤0.3). For the field experiment, B. juncea was planted in-situ in areas of low and high Cd concentrations. Brassica juncea Cd uptake was low (root and shoot BAFs <0.2) in both treatments. Sequential extraction analysis indicated that Cd is retained primarily by low bioavailability soil fractions, and phytoextraction is therefore not feasible at this site. Though low Cd bioavailability has negative implications for Cd phytoextraction from MSW/SS compost-based soils, it may limit receptor exposure to Cd sufficiently to eliminate the potential for risk at this site.

Ethnobotanical study of medicinal plants used by Sabaots of Mt. Elgon Kenya.

PubMed

Okello, S V; Nyunja, R O; Netondo, G W; Onyango, J C

2009-10-15

Though the majority of people in Kenya and at Kopsiro Division in particular, rely on ethnomedicinal plant species to manage human ailments, the indigenous knowledge largely remains undocumented. Therefore, an ethnobotanical study was conducted on medicinal plant species used to manage human ailments at Kopsiro Division Mt. Elgon District Kenya. The objectives were to identify and document plants traditionally used for medicinal therapy by the Sabaots, to find out the method used for preparing and administering the drugs and to find out the conservation practices for the medicinal plants. Observations and semi-structured interviews were used to gather ethnobotanical data. 107 plants belonging to 56 families were identified and reported to be of medicinal value to the locals. Roots (47.3%) were the most frequently used parts of the plant followed by the bark (23.35%) then leaves (22.75%). The whole plant (1.8%), seed (1.2%), fruit (1.2%), sap (1.2%), flower (0.6%) and wood (0.6%) are least used in that order. The study revealed other hitherto undocumented medicinal plant species that may be new records for treating various ailments. Traditional medicine in Kopsiro division offers cheap, accessible and convenient remedy that suits the traditional lifestyle of the local community in comparison to the conventional medicine. Most medicinal plant species reported in this study were found to be under threat and this calls for urgent conservation measures so as to maximize the sustainable use of these vital resources in the study area.

Human reliability and plant operating efficiency: Are 12-hour work schedules cause for concern

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, T.L.

1992-01-01

Since the introduction of 12-h shifts to the US nuclear power industry only 8 yr ago, compressed workweek schedules have proliferated among operations departments at a phenomenal rate. Many plants that continue to use 8-h shifts during normal operations routinely change to scheduled 12-h shifts during refueling or maintenance outages. The most critical issue in the use of extended work shifts is whether alertness, physical stamina, or mental performance are compromised to the point of reducing safety or efficiency of nuclear power plant operation. Laboratory and field research sponsored by the National Institute of Occupational Safety and Health suggests thatmore » alertness, measured by self-ratings, and mental performance, measured by computer-based performance tests, are impaired on 12-h shifts compared with 8-h shifts. In contrast to these findings, plant operating efficiency and operator performance have been rated as improved in two field studies conducted in operating nuclear power plants (Fast Flux Test Facility, Washington and Ontario Hydro, Canada). A recent Electric Power Research Institute review of nuclear industry experience with 12-h shifts also suggests an overwhelmingly positive rating of 12-h schedules from both control room operators and management.« less

Remedial Investigation Badger Army Ammunition Plant, Baraboo, Wisconsin. Volume 1. Text Sections 1 Through 12

DTIC Science & Technology

1993-04-01

VOCs (acetone [ACET], trichlorofluoromethane [CCL3F], methyl ethyl ketone [MEK]) sporadically detected at very low concentrations (< 1 parts per billion...associated with the site includes red pine ( Pinus resinosa), hickories, cedar (Thuja occidentalis), and American elm (Ulmus americana). Grasses and weedy...cd)pyrene ICDPYR iron FE lead PB magnesium MG *manganese MN mercury HG methylene chloride CH12CL2 methyl ethyl ketone or 2-butanone MIEK

A case study of risk assessment in contaminated site remediation in China

NASA Astrophysics Data System (ADS)

Ye, S.; Guo, J.; Wu, J.; Wang, J.; Chien, C.; Stahl, R.; Mack, E.; Grosso, N.

2013-12-01

A field site in Nanjing, China was selected for a case study of risk assessment in contaminated site remediation. This site is about 100m long and 100m wide. A chemical plant (1999-2010) at the site manufactured optical brightener PF, 2-Amino-4-methylphenol and 2-Nitro-4-methylphenol, totally three products. Soil and groundwater samples were collected and analyzed for PPL 126 (126 pollutants in the 'Priority Pollutants List' issued by US EPA). Values of the Dutch Standards were used as the screening criteria for soil and ground water. Low levels of ethylbenezene, chlorobenzene, 1,3-dichlorobenzene and 1,4- dichlorobenzene were detected in one soil sample. Concentrations above Dutch Target Value (DTV) of benzene, toluene, ethylbenzene, chlorobenzene, 1,2-dichlorobenzene, 1,3-dichlorobenzene, 1,4-dichlorobenzene, and/or 1,2,4-trichlorobenzene, phenol, and/or 2,4-dichlorophenol were exhibited in two groundwater samples. The ground water was especially highly impacted by bichlorobenzenes and trichlorobenzenes. The maximum concentration of impacts was 7.3 mg/L of 1,2,4-trichlorobenzene in groundwater which was 730 times higher than Dutch Intervention Values (DIV). Risk of soil and groundwater at this site was assessed according to the guidelines issued by Chinese MEP and US EPA, respectively. Finally, remedy techniques were selected according to the result of risk assessment and the characteristics of hydrogeology conditions and contaminants.

45. STEEL FRAMING FOR LOFT, Y&D No. 107723 Scales 1/2' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

45. STEEL FRAMING FOR LOFT, Y&D No. 107723 Scales 1/2' and 1-1/2' = 1'; July 2, 1929 - U.S. Naval Submarine Base, New London Submarine Escape Training Tank, Albacore & Darter Roads, Groton, New London County, CT

Factors associated with clinical skill remediation in dental hygiene education programs.

PubMed

Wood, Donna F; Mitchell, Tanya Villalpando; Holt, Lorie A; Branson, Bonnie G

2014-02-01

The purpose of this study was to examine the challenges related to formal clinical remediation in dental hygiene programs, which include timing of student identification, policy development, and the issues of methodology and scheduling. A 23 item investigator-designed survey was electronically distributed to all 303 U.S. entry-level dental hygiene program directors. This questionnaire included 23 forced-choice questions with the options to add comments to 8 of the questions. A total of 111 surveys were returned yielding a response rate of 36%. Descriptive statistics and Chi-square analyses were utilized to analyze relationships between responses and the degree earned from the dental hygiene program. All schools reported having a remediation policy; however, 13.6% of the respondents revealed this information was not readily available to students. The majority of respondents (67.8%) reported identifying students with clinical deficiencies in the preclinical semester, and 15.5% identified students in the second year, second clinical semester. Instrumentation technique was identified as the area in greatest need of remediation (81%), followed by critical thinking and problem solving skills (12%). Coordination of faculty and student schedules to conduct remediation was identified as one of the greatest challenges by respondents (25.2%). Results of this study suggest that challenges exist with the process of remediation. Some of these challenges include involving the student in remedial plan development, the academic consequences associated with remediation and scheduling time and space for remedial activities. These findings indicate that respondents are well aware of the need for remediation policies in dental hygiene programs. The point in time varies when students in need of remediation are identified. Therefore, further research needs to be conducted to determine the reasons for this difference. Some reasons may include inability to grasp the foundational skills and

Sputtering growth of Y3Fe5O12/Pt bilayers and spin transfer at Y3Fe5O12/Pt interfaces

NASA Astrophysics Data System (ADS)

Chang, Houchen; Liu, Tao; Reifsnyder Hickey, Danielle; Janantha, P. A. Praveen; Mkhoyan, K. Andre; Wu, Mingzhong

2017-12-01

For the majority of previous work on Y3Fe5O12 (YIG)/normal metal (NM) bi-layered structures, the YIG layers were grown on Gd3Ga5O12 first and were then capped by an NM layer. This work demonstrates the sputtering growth of a Pt/YIG structure where the Pt layer was grown first and the YIG layer was then deposited on the top. The YIG layer shows well-oriented (111) texture, a surface roughness of 0.15 nm, and an effective Gilbert damping constant less than 4.7 × 10-4, and the YIG/Pt interface allows for efficient spin transfers. This demonstration indicates the feasibility of fabricating high-quality NM/YIG/NM tri-layered structures for new physics studies.

Development and applications of groundwater remediation technologies in the USA

NASA Astrophysics Data System (ADS)

Barcelona, Michael J.

2005-03-01

The future of the development and application of groundwater remediation technologies will unfold in an atmosphere of heightened public concern and attention. Cleanup policy will undergo incremental change towards more comprehensive efforts which account for the impact of remediation on nearby resources. Newly discovered contaminants will cause the re-examination of "mature" technologies since they may be persistent, mobile and difficult to treat in-situ. Evaluations of the effectiveness of remedial technologies will eventually include by-product formation, geochemical consequences and sustainability. Long-term field trials of remedial technologies alone can provide the data necessary to support claims of effectiveness. Dans le futur, le développement et les applications des technologies de traitement des eaux souterraines seront déroulés en tenant compte de l'inquiétude et l'attention croissante de l'opinion publique. La politique de nettoyage va subir un changement vers des efforts plus compréhensifs qui prendront en compte l'impact du traitement sur les ressources voisines. Les nouveaux contaminants seront persistants, mobiles et difficile de traiter in situ; par conséquence ils vont provoquer la reexamination des technologies consacrées. L'évaluation de l'efficacité des technologies de traitement doit considérer l'apparition des produits secondaires ainsi que les conséquences géochimiques et le développement durable. Seulement les essais in situ, pendant des longues périodes sur les technologies peuvent fournir les éléments nécessaires pour démontrer leur efficacité. El futuro del desarrollo y de la aplicación de las tecnologías para la recuperación del agua subterránea, se revelará en una atmósfera de gran atención e interés público elevado. La política de limpieza sufrirá un cambio adicional hacia esfuerzos más tangibles, los cuales incluyan el impacto de la recuperación en los recursos circundantes. Los contaminantes

Feasibility study on phyto-remediation techniques for soil contaminated by the Fukushima Dai-Ichi nuclear power plant accident

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yuu Ishimori; Akihiro Sakoda; Mina Yamada

2013-07-01

Tottori University and the Japan Atomic Energy Agency carried out jointly the feasibility study on phyto-remediation techniques, which apply to soil contaminated by the TEPCO's Fukushima Dai-ichi NPP accident. This paper illustrates the results from experimental investigations. Experimental investigations include both water-culture tests and field tests. Several plants, mainly halophytes that can specifically absorb more Na than K, and others like sunflower demonstrated for other domestic large-scale tests, were water-cultured and examined for screening. Easily cultivated and harvested plants without harmful effects on subsequent cultivation were also considered. New Zealand spinach was selected as a candidate for demonstrations in fields.more » The field tests were carried out at two sites of different agricultural types in Minami-soma, Fukushima prefecture. Concentration of {sup 137}Cs in soil is about 4.5 Bq/g-dry as the average of 10 cm depth. The aims of the field tests are to confirm absorption ability and environmental adaptation of the test plants and to document the cost and performance of projects. In conclusion, the absorption of {sup 137}Cs activity per unit area (Bq/m{sup 2}) by New Zealand spinach could be approximately 0.5%. To achieve an effective result in removal of {sup 137}Cs from soil in around a decade, it is required to find the plant which has ten or more times higher absorption capacity than New Zealand spinach. From the consistency of both results in water-culture and field tests, the water-culture test can be valid for screening. In addition, applicable sites will be limited to fields which are too steep or too narrow to use mechanical diggers, and which are free from any restrictions to enter. (authors)« less

Trichoderma virens PDR-28: a heavy metal-tolerant and plant growth-promoting fungus for remediation and bioenergy crop production on mine tailing soil.

PubMed

Babu, A Giridhar; Shim, Jaehong; Bang, Keuk-Soo; Shea, Patrick J; Oh, Byung-Taek

2014-01-01

A heavy metal-tolerant fungus, Trichoderma virens PDR-28, was isolated from rhizosphere soil and evaluated for use in remediating mine tailing soil and for plant biomass production. PDR-28 exhibited plant growth-promoting traits, including 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase, acid phosphatase and phytase activity, siderophore production, and P solubilization. HMs were more available in mine tailing soil inoculated soil with PDR-28 than in uninoculated soil; the order of HM bioleaching was Cd > As > Zn > Pb > Cu. PDR-28 effectively removed HMs in the order of Pb > Cd > As > Zn > Cu from liquid media containing 100 mg HM L(-1). Inoculating HM-contaminated mine tailing soil with the fungus significantly increased the dry biomass of maize roots (64%) and shoots (56%). Chlorophyll, total soluble sugars (reducible and nonreducible), starch, and protein contents increased by 46%, 28%, 30%, and 29%, respectively, compared to plants grown in uninoculated soil. Inoculation increased heavy metal concentrations in maize roots by 25% (Cu) to 62% (Cd) and in shoots by 35% (Cu) to 64% (Pb) compared to uninoculated plants. Results suggest that PDR-28 would be beneficial for phytostabilization and plant biomass production as a potential source of biofuel in the quest for renewable energy. Copyright © 2013. Published by Elsevier Ltd.

Assessing market-sold remedies in lomé (togo) for hygienic quality.

PubMed

de Souza, Comlan; Ameyapoh, Yaovi; Karou, Simplice D; Anani, Kokou T; Kpodar, Madje L; Gbeassor, Mensavi

2011-01-01

Traditional concoctions sold in marketplaces are always assumed to be safe and efficient; however, they can be potentially toxic because of poor hygienic practices in plant processing or storage. The present study aimed to assess for the microbial quality of market-sold vegetable drugs in Lomé. Thus, a total of 209 plant remedies were collected in marketplaces and analysed for the presence of total aerobic bacteria, total coliforms, thermotolerant coliforms, Staphylococcus aureus, sulphite reducing bacteria, and yeast and moulds according to the French Association of Normalisation (AFNOR) guidelines. The results revealed that all formulations were contaminated by several microorganisms, excepted alcohol-based mixtures. According to AFNOR limits nonconform drugs were according to total aerobic bacteria (86.96% powders, 81.82% capsules, 66.67% tisanes, and 42.11% decoctions); to total coliforms (9.10% capsules, 8.70% powders and 1.75% decoction); to yeasts and moulds (77.78% ointments, 40% calcined powders, 36.36% capsules, and 23.91% powders). The microbiological analysis revealed that the majority of contaminating bacteria were gram positive catalase positive and oxidase positive bacilli. Quality control studies on market-sold remedies are currently needed to evaluate the microbial risk in consuming these products and they may allow the standardisation of plant processing and storage.

Assessing Market-Sold Remedies in Lomé (Togo) for Hygienic Quality

PubMed Central

de Souza, Comlan; Ameyapoh, Yaovi; Karou, Simplice D.; Anani, Kokou T.; Kpodar, Madje L.; Gbeassor, Mensavi

2011-01-01

Traditional concoctions sold in marketplaces are always assumed to be safe and efficient; however, they can be potentially toxic because of poor hygienic practices in plant processing or storage. The present study aimed to assess for the microbial quality of market-sold vegetable drugs in Lomé. Thus, a total of 209 plant remedies were collected in marketplaces and analysed for the presence of total aerobic bacteria, total coliforms, thermotolerant coliforms, Staphylococcus aureus, sulphite reducing bacteria, and yeast and moulds according to the French Association of Normalisation (AFNOR) guidelines. The results revealed that all formulations were contaminated by several microorganisms, excepted alcohol-based mixtures. According to AFNOR limits nonconform drugs were according to total aerobic bacteria (86.96% powders, 81.82% capsules, 66.67% tisanes, and 42.11% decoctions); to total coliforms (9.10% capsules, 8.70% powders and 1.75% decoction); to yeasts and moulds (77.78% ointments, 40% calcined powders, 36.36% capsules, and 23.91% powders). The microbiological analysis revealed that the majority of contaminating bacteria were gram positive catalase positive and oxidase positive bacilli. Quality control studies on market-sold remedies are currently needed to evaluate the microbial risk in consuming these products and they may allow the standardisation of plant processing and storage. PMID:21350662

Bio-prospecting of distillery yeasts as bio-control and bio-remediation agents.

PubMed

Ubeda, Juan F; Maldonado, María; Briones, Ana I; Francisco, J Fernández; González, Francisco J

2014-05-01

This work constitutes a preliminary study in which the capacity of non-Saccharomyces yeasts isolated from ancient distilleries as bio-control agents against moulds and in the treatment of waste waters contaminated by heavy metals-i.e. bio-remediation-is shown. In the first control assays, antagonist effect between non-Saccharomyces yeasts, their extracts and supernatants against some moulds, analysing the plausible (not exhaustive) involved factors were qualitatively verified. In addition, two enzymatic degrading properties of cell wall plant polymers, quitinolitic and pectinolitic, were screened. Finally, their use as agents of bio-remediation of three heavy metals (cadmium, chromium and lead) was analysed semi-quantitatively. The results showed that all isolates belonging to Pichia species effectively inhibited all moulds assayed. Moreover, P. kudriavzevii is a good candidate for both bio-control and bio-remediation because it inhibited moulds and accumulated the major proportion of the three tested metals.

Co-remediation of the lead-polluted garden soil by exogenous natural zeolite and humic acids.

PubMed

Shi, Wei-yu; Shao, Hong-bo; Li, Hua; Shao, Ming-an; Du, Sheng

2009-08-15

The current study reported the co-remediation effect on the lead-polluted garden soil by zeolite and humic acids (HA), which was from comparing with the remediation of single zeolite in term of the lead fraction of sequential extraction in the soil and the distribution of lead in different parts of rape. Mixed treatment (zeolite and HA) and single treatment (zeolite) were, respectively, applied to the artificially polluted garden soil to examine the difference of their remediation effects in pot experiment. Results indicated that the co-remediation led to significantly greater (p<0.01) reduction in the lead concentration in plants than by singly adding to zeolite. The co-application of zeolite and HA reduced the available fraction of lead compounds, but slightly increased (p<0.01) the water-soluble fraction of lead compounds in the garden soil, compared with the application of single zeolite, especially in the severe lead-polluted soil (> or =1000 mg kg(-1)). This method might be an efficient way to remediate the lead-polluted soils on a large scale, although zeolite is a kind of hazardous material.

Continuous-wave and Q-switched microchip laser performance of Yb:Y3Sc2Al3O12 crystals.

PubMed

Dong, Jun; Ueda, Ken-ichi; Kaminskii, Alexander A

2008-04-14

Optical properties of Yb:Y(3)Sc(2)Al(3)O(12) crystal were investigated and compared with those from Yb:YAG crystals. The broad absorption and emission spectra of Yb:Y(3)Sc(2)Al(3)O(12) show that this crystal is very suitable for laser-diode pumping and ultrafast laser pulse generation. Laser-diode pumped continuous-wave and passively Q-switched Yb:Y(3)Sc(2)Al(3)O(12) lasers with Cr(4+):YAG crystals as saturable absorber have been demonstrated for the first time. Continuous-wave output power of 1.12 W around 1032 nm (multi-longitudinal modes) was measured with an optical-to-optical efficiency of 30%. Laser pulses with pulse energy of over 31 microJ and pulse width of 2.5 ns were measured at repetition rate of over 12.7 kHz; a corresponding peak power of over 12 kW was obtained. The longitudinal mode selection by a thin plate of Cr(4+):YAG as an intracavity etalon was also observed in passively Q-switched Yb:Y(3)Sc(2)Al(2)O(12) microchip lasers.

Testing amendments for remediation of military range contaminated soil.

PubMed

Siebielec, Grzegorz; Chaney, Rufus L

2012-10-15

Military range soils are often strongly contaminated with metals. Information on the effectiveness of remediation of these soils is scarce. We tested the effectiveness of compost and mineral treatments for remediation and revegetation of military range soil collected in Aberdeen, MD. The soil was barren due to zinc (Zn) phytotoxicity while lead (Pb) posed a substantial risk to soil biota, wildlife and humans through various pathways. Seven treatments were tested: untreated control, agricultural NPK fertilization, high phosphate fertilization plus agricultural rates of NK, CaCO(3), "Orgro" biosolid compost, "Orgro" + CaCO(3), "Orgro" + CaCO(3) + Mn sulfate. All compost treatments alleviated Zn phytotoxicity to tall fescue; however compost combined with liming reduced plant Zn content up to 158-162 mg kg(-1). Compost added with lime reduced Pb in-vitro bioaccessibility from 32.5 to 20.4% of total Pb and was the most effective among the tested treatments. The study revealed the effectiveness of biosolids compost and lime mixture in the rapid stabilization of metals and revegetation of military range contaminated soils. The persistence of the remediation needs to be, however, confirmed in the long-term field study. Copyright © 2012 Elsevier Ltd. All rights reserved.

43 CFR 20.602 - Remedial action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Remedial action. 20.602 Section 20.602... Disciplinary and Remedial Actions § 20.602 Remedial action. (a)(1) Remedial action should normally be.... (2) If the bureau Ethics Counselor decides that remedial action is required, such action shall be...

Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads to rapamycin susceptibility.

PubMed

Sormani, Rodnay; Yao, Lei; Menand, Benoît; Ennar, Najla; Lecampion, Cécile; Meyer, Christian; Robaglia, Christophe

2007-06-01

The eukaryotic TOR pathway controls translation, growth and the cell cycle in response to environmental signals such as nutrients or growth-stimulating factors. The TOR protein kinase can be inactivated by the antibiotic rapamycin following the formation of a ternary complex between TOR, rapamycin and FKBP12 proteins. The TOR protein is also found in higher plants despite the fact that they are rapamycin insensitive. Previous findings using the yeast two hybrid system suggest that the FKBP12 plant homolog is unable to form a complex with rapamycin and TOR, while the FRB domain of plant TOR is still able to bind to heterologous FKBP12 in the presence of rapamycin. The resistance to rapamycin is therefore limiting the molecular dissection of the TOR pathway in higher plants. Here we show that none of the FKBPs from the model plant Arabidopsis (AtFKBPs) is able to form a ternary complex with the FRB domain of AtTOR in the presence of rapamycin in a two hybrid system. An antibody has been raised against the AtTOR protein and binding of recombinant yeast ScFKBP12 to native Arabidopsis TOR in the presence of rapamycin was demonstrated in pull-down experiments. Transgenic lines expressing ScFKBP12 were produced and were found to display a rapamycin-dependent reduction of the primary root growth and a lowered accumulation of high molecular weight polysomes. These results further strengthen the idea that plant resistance to rapamycin evolved as a consequence of mutations in plant FKBP proteins. The production of rapamycin-sensitive plants through the expression of the ScFKBP12 protein illustrates the conservation of the TOR pathway in eukaryotes. Since AtTOR null mutants were found to be embryo lethal 1, transgenic ScFKBP12 plants will provide an useful tool for the post-embryonic study of plant TOR functions. This work also establish for the first time a link between TOR activity and translation in plant cells.

Comparative study of remediation of Cr(VI)-contaminated soil using electrokinetics combined with bioremediation.

PubMed

He, Jiaying; He, Chiquan; Chen, Xueping; Liang, Xia; Huang, Tongli; Yang, Xuecheng; Shang, Hai

2018-06-01

The purpose of this research is to design a new bioremediation-electrokinetic (Bio-EK) remediation process to increase treatment efficiency of chromium contamination in soil. Upon residual chromium analysis, it is shown that traditional electrokinetic-PRB system (control) does not have high efficiency (80.26%) to remove Cr(VI). Bio-electrokinetics of exogenous add with reduction bacteria Microbacterium sp. Y2 and electrokinetics can enhance treatment efficiency Cr(VI) to 90.67% after 8 days' remediation. To optimize the overall performance, integrated bio-electrokinetics were designed by synergy with 200 g humic substances (HS) into the systems. According to our results, Cr(VI) (98.33%) was effectively removed via electrokinetics. Moreover, bacteria and humic substances are natural, sustainable, and economical enhancement agents. The research results indicated that the use of integrated bio-electrokinetics is an effective method to remediate chromium-contaminated soils.

Evaluation of home lead remediation in an Australian mining community.

PubMed

Boreland, F; Lesjak, M; Lyle, D

2009-12-20

In 1994 a comprehensive program was established to reduce children's blood lead levels in Broken Hill, NSW, Australia. Home remediation (abatement of lead hazards in a child's home) was included as part of a case management strategy for children with blood lead levels >or=15 microg/dL. Children with blood lead levels >or=30 microg/dL were offered immediate home remediation. Children with blood lead levels of 15-29 microg/dL were allocated to 'immediate' or 'delayed' home remediation; a subset of these participated in a randomized controlled trial (RCT) to evaluate the effectiveness of home remediation for reducing blood lead levels. One hundred and seventeen children received home remediation. One hundred and thirteen returned for follow-up blood tests, 88 of whom participated in the RCT. On average children's blood lead levels decreased by 1.7 microg/dL (10%) in the 6 months after remediation and by 2.2 microg/dL (13%) in the 6-12 months after remediation. However, remediation did not significantly change the rate of decline in blood lead levels (P=0.609). There was no evidence of association between change in children's blood lead levels and changes in lead loading in their homes. The results are consistent with the published literature, which suggests that home remediation does not reduce children's exposure to lead sufficiently to cause a moderate or greater decrease in their blood lead level. In communities where lead is widely dispersed, the study suggests that it is important to assess potential sources and pathways by which children are exposed to lead when developing an intervention plan, and the need for multiple interventions to effectively reduce blood lead levels. The findings reinforce the ongoing need for rigorous epidemiological evaluation of lead management programs to improve the evidence base, and for effective primary prevention to avoid children being exposed to lead in the first place.

Review on utilization of biochar for metal-contaminated soil and sediment remediation.

PubMed

Wang, Mingming; Zhu, Yi; Cheng, Lirong; Andserson, Bruce; Zhao, Xiaohui; Wang, Dayang; Ding, Aizhong

2018-01-01

Biochar is a carbon-neutral or even carbon-negative material produced through thermal decomposition of plant- and animal-based biomass under oxygen-limited conditions. Recently, there has been an increasing interest in the application of biochar as an adsorbent, soil ameliorant and climate mitigation approach in many types of applications. Metal-contaminated soil remediation using biochar has been intensively investigated in small-scale and pilot-scale trials with obtained beneficial results and multifaceted effects. But so far, the study and application of biochar in contaminated sediment management has been very limited, and this is also a worldwide problem. Nonetheless, there is reason to believe that the same multiple benefits can also be realized with these sediments due to similar mechanisms for stabilizing contaminants. This paper provides a review on current biochar properties and its use as a sorbent/amendment for metal-contaminated soil/sediment remediation and its effect on plant growth, fauna habits as well as microorganism communities. In addition, the use of biochar as a potential strategy for contaminated sediment management is also discussed, especially as regards in-situ planning. Finally, we highlight the possibility of biochar application as an effective amendment and propose further research directions to ensure the safe and sustainable use of biochar as an amendment for remediation of contaminated soil and sediment. Copyright © 2017. Published by Elsevier B.V.

Traditional herbs: a remedy for cardiovascular disorders.

PubMed

Rastogi, Subha; Pandey, Madan Mohan; Rawat, A K S

2016-10-15

Medicinal plants have been used in patients with congestive heart failure, systolic hypertension, angina pectoris, atherosclerosis, cerebral insufficiency, venous insufficiency and arrhythmia since centuries. A recent increase in the popularity of alternative medicine and natural products has revived interest in traditional remedies that have been used for the treatment of cardiovascular diseases. The purpose of this review is to provide updated, comprehensive and categorized information on the history and traditional uses of some herbal medicines that affect the cardiovascular system in order to explore their therapeutic potential and evaluate future research opportunities. Systematic literature searches were carried out and the available information on various medicinal plants traditionally used for cardiovascular disorders was collected via electronic search (using Pubmed, SciFinder, Scirus, GoogleScholar, JCCC@INSTIRC and Web of Science) and a library search for articles published in peer-reviewed journals. No restrictions regarding the language of publication were imposed. This article highlights the cardiovascular effects of four potent traditional botanicals viz. Garlic (Allium sativum), Guggul (Commiphora wightii), Hawthorn (Crataegus oxyacantha) and Arjuna (Terminalia arjuna). Although these plants have been used in the treatment of heart disease for hundreds of years, current research methods show us they can be utilized effectively in the treatment of cardiovascular diseases including ischemic heart disease, congestive heart failure, arrhythmias and hypertension. Although the mechanisms of action are not very clear, there is enough evidence of their efficacy in various cardiovascular disorders. However, for bringing more objectivity and also to confirm traditional claims, more systematic, well-designed animal and randomized clinical studies with sufficient sample sizes are necessary. Multidisciplinary research is still required to exploit the vast

The minor spliceosomal protein U11/U12-31K is an RNA chaperone crucial for U12 intron splicing and the development of dicot and monocot plants.

PubMed

Kwak, Kyung Jin; Jung, Hyun Ju; Lee, Kwang Ho; Kim, Young Soon; Kim, Won Yong; Ahn, Sung Ju; Kang, Hunseung

2012-01-01

U12 intron-specific spliceosomes contain U11 and U12 small nuclear ribonucleoproteins and mediate the removal of U12 introns from precursor-mRNAs. Among the several proteins unique to the U12-type spliceosomes, an Arabidopsis thaliana AtU11/U12-31K protein has been shown to be indispensible for proper U12 intron splicing and for normal growth and development of Arabidopsis plants. Here, we assessed the functional roles of the rice (Oryza sativa) OsU11/U12-31K protein in U12 intron splicing and development of plants. The U11/U12-31K transcripts were abundantly expressed in the shoot apical meristems (SAMs) of Arabidopsis and rice. Ectopic expression of OsU11/U12-31K in AtU11/U12-31K-defecient Arabidopsis mutant complemented the incorrect U12 intron splicing and abnormal development phenotypes of the Arabidopsis mutant plants. Impaired cell division activity in the SAMs and inflorescence stems observed in the AtU11/U12-31K-deficient mutant was completely recovered to normal by the expression of OsU11/U12-31K. Similar to Arabidopsis AtU11/U12-31K, rice OsU11/U12-31K was determined to harbor RNA chaperone activity. Collectively, the present findings provide evidence for the emerging idea that the U11/U12-31K protein is an indispensible RNA chaperone that functions in U12 intron splicing and is necessary for normal development of monocotyledonous plants as well as dicotyledonous plants.

Efficiency of modified chemical remediation techniques for soil contaminated by organochlorine pesticides

NASA Astrophysics Data System (ADS)

Correa-Torres, S. N.; Kopytko, M.; Avila, S.

2016-07-01

This study reports the optimization of innovation chemical techniques in order to improve the remediation of soils contaminated with organochloride pesticides. The techniques used for remediation were dehalogenation and chemical oxidation in soil contaminated by pesticides. These techniques were applied sequentially and combined to evaluate the design optimize the concentration and contact time variables. The soil of this study was collect in cotton crop zone in Agustin Codazzi municipality, Colombia, and its physical properties was measure. The modified dehalogenation technique of EPA was applied on the contaminated soil by adding Sodium Bicarbonate solution at different concentrations and rates during 4, 7 and 14 days, subsequently oxidation technique was implemented by applying a solution of KMnO4 at different concentration and reaction times. Organochlorine were detected by Gas Chromatography analysis coupled Mass Spectrometry and its removals were between 85.4- 90.0% of compounds such as 4, 4’-DDT, 4,4’-DDD, 4,4-DDE, trans-Clordane y Endrin. These results demonstrate that the technique of dehalogenation with oxidation chemistry can be used for remediation soils contaminated by organochloride pesticides.

Does ochre have the potential to be a remedial treatment for As-contaminated soils?

PubMed

Olimah, J A; Shaw, L J; Hodson, M E

2015-11-01

Ochre is an iron oxyhydroxide-rich waste that accumulates in water bodies associated with disused mines. Laboratory experiments were conducted to examine the potential of four different ochres to be used as remedial agents for As contaminated soils. The ochres removed As from solution (200 and 500 mg L(-1)) in adsorption experiments at pH 3 and 8 and, when added to As contaminated soil (5% w/w) significantly reduced As release to solution. In both these experiments the highest surface area ochres performed best. The impact of ochre amendments on uptake of As from soil by plants and humans and release of As to ground water was assessed in a year-long incubation study. Ochres increased soil pH and reduced CaCl2 extractable As but had no consistent effect on plant growth, plant As uptake or As extraction in physiologically-based extraction tests. Ochre may be better used for water treatment than soil remediation. Copyright © 2015 Elsevier Ltd. All rights reserved.

Electrokinetic remediation of fluorine-contaminated soil and its impact on soil fertility.

PubMed

Zhou, Ming; Wang, Hui; Zhu, Shufa; Liu, Yana; Xu, Jingming

2015-11-01

Compared to soil pollution by heavy metals and organic pollutants, soil pollution by fluorides is usually ignored in China. Actually, fluorine-contaminated soil has an unfavorable influence on human, animals, plants, and surrounding environment. This study reports on electrokinetic remediation of fluorine-contaminated soil and the effects of this remediation technology on soil fertility. Experimental results showed that electrokinetic remediation using NaOH as the anolyte was a considerable choice to eliminate fluorine in contaminated soils. Under the experimental conditions, the removal efficiency of fluorine by the electrokinetic remediation method was 70.35%. However, the electrokinetic remediation had a significant impact on the distribution and concentrations of soil native compounds. After the electrokinetic experiment, in the treated soil, the average value of available nitrogen was raised from 69.53 to 74.23 mg/kg, the average value of available phosphorus and potassium were reduced from 20.05 to 10.39 mg/kg and from 61.31 to 51.58 mg/kg, respectively. Meanwhile, the contents of soil available nitrogen and phosphorus in the anode regions were higher than those in the cathode regions, but the distribution of soil available potassium was just the opposite. In soil organic matter, there was no significant change. These experiment results suggested that some steps should be taken to offset the impacts, after electrokinetic treatment.

ELECTROCHEMICAL REMEDIATION TECHNOLOGIES (ECRTS) - IN SITU REMEDIATION OF CONTAMINATED MARINE SEDIMENTS

EPA Science Inventory

This Innovative Technology Evaulation Report summarizes the results of the evaluation of the Electrochemical Remediation Technologies (ECRTs) process, developed by P2-Soil Remediation, Inc. (in partnership with Weiss Associates and Electro-Petroleum, Inc.). This evaluation was co...

Remediating Remediation: From Basic Writing to Writing across the Curriculum

ERIC Educational Resources Information Center

Faulkner, Melissa

2013-01-01

This article challenges faculty members and administrators to rethink current definitions of remediation. First year college students are increasingly placed into basic writing courses due to a perceived inability to use English grammar correctly, but it must be acknowledged that all students will encounter the need for remediation as they attempt…

Soil Contamination and Remediation Strategies. Current research and future challenge

NASA Astrophysics Data System (ADS)

Petruzzelli, G.

2012-04-01

Soil contamination: the heritage of industrial development Contamination is only a part of a whole set of soil degradation processes, but it is one of paramount importance since soil pollution greatly influences the quality of water, food and human health. Soil contamination has been identified as an important issue for action in the European strategy for soil protection, it has been estimated that 3.5 million of sites are potentially contaminated in Europe. Contaminated soils have been essentially discovered in industrial sites landfills and energy production plants, but accumulation of heavy metals and organic compounds can be found also in agricultural land . Remediation strategies. from incineration to bioremediation The assessment of soil contamination is followed by remedial action. The remediation of contaminated soils started using consolidates technologies (incineration inertization etc.) previously employed in waste treatment,. This has contributed to consider a contaminated soil as an hazardous waste. This rough approximation was unfortunately transferred in many legislations and on this basis soil knowledge have been used only marginally in the clean up procedures. For many years soil quality has been identified by a value of concentration of a contaminant and excavation and landfill disposal of soil has been largely used. In the last years the knowledge of remediation technology has rapidly grown, at present many treatment processes appear to be really feasible at field scale, and soil remediation is now based on risk assessment procedures. Innovative technologies, largely dependent on soil properties, such as in situ chemical oxidation, electroremediation, bioventing, soil vapor extraction etc. have been successfully applied. Hazardous organic compounds are commonly treated by biological technologies, biorememdiation and phytoremediation, being the last partially applied also for metals. Technologies selection is no longer exclusively based on

Microbiological Assessment of Moringa Oleifera Extracts and Its Incorporation in Novel Dental Remedies against Some Oral Pathogens

PubMed Central

Elgamily, Hanaa; Moussa, Amani; Elboraey, Asmaa; EL-Sayed, Hoda; Al-Moghazy, Marwa; Abdalla, Aboelfetoh

2016-01-01

AIM: To assess the antibacterial and antifungal potentials of different parts of Moringa oleifera plant using different extraction methods in attempts to formulate natural dental remedies from this plant. MATERIAL AND METHODS: Three solvents extracts (Ethanol, acetone, and ethyl acetate) of different parts of Egyptian Moringa tree were prepared and tested against oral pathogens: Staphylococcus aureus, Streptococcus mutans, and Candida albicans using disc diffusion method; As well as to incorporate the plant extract to formulate experimental toothpaste and mouthwash. The two dental remedies were assessed against the same microbial strains. Statistical analysis was performed using One-Way ANOVA test to compare the inhibition zone diameter and t-test. RESULTS: Ethanol extracts as well as leaves extracts demonstrated the highest significant mean inhibition zone values (P ≤ 0.05) against Staphylococcus aureus and Streptococcus mutans growth. However, all extracts revealed no inhibition zone against Candida albicans. For dental remedies, experimental toothpaste exhibited higher mean inhibition than the mouthwash against Staphylococcus aureus, Streptococcus mutans and only the toothpaste revealed antifungal effect against Candida albicans. CONCLUSION: The different extracts of different parts of Moringa showed an antibacterial effect against Staphylococcus aureus and Streptococcus mutans growth. The novel toothpaste of ethanolic leaves extract has antimicrobial and antifungal potential effects all selected strains. PMID:28028395

Enterococcus faecium LKE12 Cell-Free Extract Accelerates Host Plant Growth via Gibberellin and Indole-3-Acetic Acid Secretion.

PubMed

Lee, Ko-Eun; Radhakrishnan, Ramalingam; Kang, Sang-Mo; You, Young-Hyun; Joo, Gil-Jae; Lee, In-Jung; Ko, Jae-Hwan; Kim, Jin-Ho

2015-09-01

The use of microbial extracts containing plant hormones is a promising technique to improve crop growth. Little is known about the effect of bacterial cell-free extracts on plant growth promotion. This study, based on phytohormonal analyses, aimed at exploring the potential mechanisms by which Enterococcus faecium LKE12 enhances plant growth in oriental melon. A bacterial strain, LKE12, was isolated from soil, and further identified as E. faecium by 16S rDNA sequencing and phylogenetic analysis. The plant growth-promoting ability of an LKE12 bacterial culture was tested in a gibberellin (GA)-deficient rice dwarf mutant (waito-C) and a normal GA biosynthesis rice cultivar (Hwayongbyeo). E. faecium LKE12 significantly improved the length and biomass of rice shoots in both normal and dwarf cultivars through the secretion of an array of gibberellins (GA1, GA3, GA7, GA8, GA9, GA12, GA19, GA20, GA24, and GA53), as well as indole-3-acetic acid (IAA). To the best of our knowledge, this is the first study indicating that E. faecium can produce GAs. Increases in shoot and root lengths, plant fresh weight, and chlorophyll content promoted by E. faecium LKE12 and its cell-free extract inoculated in oriental melon plants revealed a favorable interaction of E. faecium LKE12 with plants. Higher plant growth rates and nutrient contents of magnesium, calcium, sodium, iron, manganese, silicon, zinc, and nitrogen were found in cell-free extract-treated plants than in control plants. The results of the current study suggest that E. faecium LKE12 promotes plant growth by producing GAs and IAA; interestingly, the exogenous application of its cell-free culture extract can be a potential strategy to accelerate plant growth.

Herbal Remedies Used by Selected Migrant Farmworkers in El Paso, Texas

ERIC Educational Resources Information Center

Poss, Jane; Pierce, Rebecca; Prieto, Veronica

2005-01-01

Little is known about the use of complementary and alternative medicine among the approximately 1.6 million migrant farmworkers in the United States. The purpose of this work was to evaluate the use of medicinal plants and natural remedies among a convenience sample of 100 migrant farmworkers living temporarily in a migrant worker center in El…

Monitoring platelet inhibition after clopidogrel with the VerifyNow-P2Y12(R) rapid analyzer: the VERIfy Thrombosis risk ASsessment (VERITAS) study.

PubMed

Malinin, Alex; Pokov, Alex; Spergling, Malcolm; Defranco, Anthony; Schwartz, Kenneth; Schwartz, Dianne; Mahmud, Ehtisham; Atar, Dan; Serebruany, Victor

2007-01-01

Clopidogrel inhibits platelet P2Y12 ADP receptors, while ADP, as an inductor of aggregation, stimulates both P2Y12 and P2Y1 platelet receptors. Despite a clinical loading dose routine with clopidogrel, some patients still experience coronary stent thrombosis suggesting persistent platelet activation. The VerifyNow-P2Y12 is a rapid assay that test platelet activity over 3 min and uses of the combination of ADP and prostaglandin E1 (PGE1) to directly measure the effects of clopidogrel on the P2Y12 receptor. ADP is used to maximally activate the platelets by binding to the P2Y1 and P2Y12 platelet receptors, while PGE1 is used to suppress the ADP-induced P2Y1-mediated increase in intracellular calcium levels. The VERIfy Thrombosis risk ASsessment (VERITAS) was a prospective study designed to measure platelet response to clopidogrel therapy in subjects with multiple risk factors or history of vascular disease using this novel point-of-care assay. 166 participants were enrolled in 4 participating sites. Data from 147 participants were analyzed after exclusion of 19 patients due to protocol violations. Platelets were assessed twice at baseline (before clopidogrel) and at 24 h post-loading 450 mg (110 participants) or 7 days after chronic clopidogrel treatment (75 mg/day) (37 patients). All participants received aspirin 81-325 mg for at least 2 days before the study enrollment. Results from the VerifyNow-P2Y12 assay are reported in P2Y12 reaction units (PRU). Clopidogrel therapy resulted in a mean 64.0+/-25.3% PRU reduction. No participant reached PRU inhibition below 10% of baseline. Distribution of PRU values for the VerifyNow-P2Y12 assay shows a separation from baseline to post-clopidogrel assay values with some overlap due to high inter-individual variations in response. VerifyNow-P2Y12 is a reliable, fast and sensitive device suitable for monitoring of platelet inhibition during clopidogrel therapy.

Cerium LIII-edge x-ray absorption study of the CexFe4-yCoySb12 skutterudites

NASA Astrophysics Data System (ADS)

Grandjean, Fernande; Long, Gary J.; Cortes, Robert; Morelli, Donald T.; Meisner, Gregory P.

2000-11-01

The cerium LIII-edge x-ray absorption near-edge spectra of the CexFe4-yCoySb12 compounds have been obtained at 295 K and unambiguously indicate that cerium is in the 4f1 electronic ground state for all values of 0.22<=x<=0.98 and 0.0<=y<=3.5. This stable trivalent state of cerium is in agreement with the proposed (CeFe4Sb12)1-α(□Co4Sb12)α, solid solution structure, in which the cerium atoms are always surrounded by twelve antimony first neighbors and six iron second neighbors, the observed magnetic properties of CeFe4Sb12 and Ce0.9Fe3CoSb12, and the electronic structure of CeFe4Sb12 obtained from band-structure calculations.

Down with Remediation.

ERIC Educational Resources Information Center

Chaplin, Miriam T.

1979-01-01

Remedial education is contrary to traditional educational principles, for it operates only after a child has failed. Instead failure should be prevented by developmental, individualized instruction. Furthermore, remedial education isolates and emphasizes skill deficits and may lead to teaching for the test. (Author/SJL)

Optical properties of white organic light-emitting devices fabricated utilizing a mixed CaAl12O19:Mn4+ and Y3Al5O12:Ce3+ color conversion layer.

PubMed

Jeong, H S; Kim, S H; Lee, K S; Jeong, J M; Yoo, T W; Kwon, M S; Yoo, K H; Kim, T W

2013-06-01

White organic light-emitting devices (OLEDs) were fabricated by combining a blue OLED with a color conversion layer made of mixed Y3Al5O12:Ce3+ green and Ca2AlO19:Mn4+ red phosphors. The X-ray diffraction patterns showed that Ce3+ ions in the Y3Al5O12:Ce3+ phosphors completely substituted for the Y3+ ions and the Mn4+ ions in the CaAl12O19:Mn4+ phosphors completely substituted for the Ca2+ ions. Electroluminescence spectra at 11 V for the OLEDs fabricated utilizing a color conversion layer showed that the Commission Internationale de l'Eclairage coordinates for the Y3Al5O12:Ce3+ and CaAl12O19:Mn4+ phosphors mixed at the ratio of 1:5 and 1:10 were (0.31, 0.34) and (0.32, 0.37), respectively, indicative of a good white color.

Coastal hypoxia responses to remediation

NASA Astrophysics Data System (ADS)

Kemp, W. M.; Testa, J. M.; Conley, D. J.; Gilbert, D.; Hagy, J. D.

2009-07-01

The incidence and intensity of hypoxic waters in coastal aquatic ecosystems has been expanding in recent decades coincident with eutrophication of the coastal zone. Because of the negative effects hypoxia has on many organisms, extensive efforts have been made to reduce the size and duration of hypoxia in many coastal waters. Although it has been broadly assumed that reductions in nutrient loading rates would reverse eutrophication and consequently, hypoxia, recent analyses of historical data from European and North American coastal systems suggest little evidence for simple linear response trajectories. We review existing data, analyses, and models that relate variations in the extent and intensity of hypoxia to changes in loading rates for inorganic nutrients and labile organic matter. We also assess existing knowledge of physical and ecological factors regulating oxygen in coastal marine waters and examine a broad range of examples where hypoxia responses to reductions in nutrient (or organic matter) inputs have been documented. Of the 22 systems identified where concurrent time series of loading and O2 were available, half displayed relatively clear and direct recoveries following remediation. We explored in detail 5 well-studied systems that have exhibited complex, non-linear responses to loading, including apparent "regime shifts." A summary of these analyses suggests that O2 conditions improved rapidly and linearly in systems where remediation focused on organic inputs from sewage plants, which were the primary drivers of hypoxia. In larger more open systems where diffuse nutrient loads are more important in fueling O2 depletion and where climatic influences are pronounced, responses to remediation tend to follow non-linear trends that may include hysteresis and time-lags. Improved understanding of hypoxia remediation requires that future studies use comparative approaches and consider multiple regulating factors including: (1) the dominant temporal scales

The platelet P2Y(12) receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [(3)H]PSB-0413.

PubMed

Ohlmann, Philippe; Lecchi, Anna; El-Tayeb, Ali; Müller, Christa E; Cattaneo, Marco; Gachet, Christian

2013-03-01

Various radioligands have been used to characterize and quantify the platelet P2Y(12) receptor, which share several weaknesses: (a) they are metabolically unstable and substrates for ectoenzymes, (b) they are agonists, and (c) they do not discriminate between P2Y(1) and P2Y(12). We used the [(3)H]PSB-0413 selective P2Y(12) receptor antagonist radioligand to reevaluate the number of P2Y(12) receptors in intact platelets and in membrane preparations. Studies in humans showed that: (1) [(3)H]PSB-0413 bound to 425 ± 50 sites/platelet (K (D) = 3.3 ± 0.6 nM), (2) 0.5 ± 0.2 pmol [(3)H]PSB-0413 bound to 1 mg protein of platelet membranes (K (D) = 6.5 ± 3.6 nM), and (3) competition studies confirmed the known features of P2Y(12), with the expected rank order of potency: AR-C69931MX > 2MeSADP ≫ ADPβS > ADP, while the P2Y(1) ligand MRS2179 and the P2X(1) ligand α,β-Met-ATP did not displace [(3)H]PSB-0413 binding. Patients with severe P2Y(12) deficiency displayed virtually no binding of [(3)H]PSB-0413 to intact platelets, while a patient with a dysfunctional P2Y(12) receptor had normal binding. Studies in mice showed that: (1) [(3)H]PSB-0413 bound to 634 ± 87 sites/platelet (K (D) = 14 ± 4.5 nM) and (2) 0.7 pmol ± 0.3 [(3)H]PSB-0413 bound to 1 mg protein of platelet membranes (K (D) = 9.1 ± 5.3 nM). Clopidogrel and other thiol reagents like pCMBS or DTT abolished the binding both to intact platelets and membrane preparations. Therefore, [(3)H]PSB-0413 is an accurate and selective tool for radioligand binding studies aimed at quantifying P2Y(12) receptors, to identify patients with P2Y(12) deficiencies or quantify the effect of P2Y(12) targeting drugs.

Role of biochar on composting of organic wastes and remediation of contaminated soils-a review.

PubMed

Wu, Shaohua; He, Huijun; Inthapanya, Xayanto; Yang, Chunping; Lu, Li; Zeng, Guangming; Han, Zhenfeng

2017-07-01

Biochar is produced by pyrolysis of biomass residues under limited oxygen conditions. In recent years, biochar as an amendment has received increasing attention on composting and soil remediation, due to its unique properties such as chemical recalcitrance, high porosity and sorption capacity, and large surface area. This paper provides an overview on the impact of biochar on the chemical characteristics (greenhouse gas emissions, nitrogen loss, decomposition and humification of organic matter) and microbial community structure during composting of organic wastes. This review also discusses the use of biochar for remediation of soils contaminated with organic pollutants and heavy metals as well as related mechanisms. Besides its aging, the effects of biochar on the environment fate and efficacy of pesticides deserve special attention. Moreover, the combined application of biochar and compost affects synergistically on soil remediation and plant growth. Future research needs are identified to ensure a wide application of biochar in composting and soil remediation. Graphical abstract ᅟ.

Remediation of heavy metal(loid)s contaminated soils--to mobilize or to immobilize?

PubMed

Bolan, Nanthi; Kunhikrishnan, Anitha; Thangarajan, Ramya; Kumpiene, Jurate; Park, Jinhee; Makino, Tomoyuki; Kirkham, Mary Beth; Scheckel, Kirk

2014-02-15

Unlike organic contaminants, metal(loid)s do not undergo microbial or chemical degradation and persist for a long time after their introduction. Bioavailability of metal(loid)s plays a vital role in the remediation of contaminated soils. In this review, the remediation of heavy metal(loid) contaminated soils through manipulating their bioavailability using a range of soil amendments will be presented. Mobilizing amendments such as chelating and desorbing agents increase the bioavailability and mobility of metal(loid)s. Immobilizing amendments such of precipitating agents and sorbent materials decrease the bioavailabilty and mobility of metal(loid)s. Mobilizing agents can be used to enhance the removal of heavy metal(loid)s though plant uptake and soil washing. Immobilizing agents can be used to reduce the transfer to metal(loid)s to food chain via plant uptake and leaching to groundwater. One of the major limitations of mobilizing technique is susceptibility to leaching of the mobilized heavy metal(loid)s in the absence of active plant uptake. Similarly, in the case of the immobilization technique the long-term stability of the immobilized heavy metal(loid)s needs to be monitored. Copyright © 2013 Elsevier B.V. All rights reserved.

Evaluation of antibacterial activity, phytochemical constituents, and cytotoxicity effects of Thai household ancient remedies.

PubMed

Chusri, Sasitorn; Sinvaraphan, Naruephan; Chaipak, Ploypailin; Luxsananuwong, Atita; Voravuthikunchai, Supayang Piyawan

2014-12-01

Household ancient remedies reported here are described in the National List of Essential Medicines and have traditionally been used in Thailand to treat infection-related ailments. However, the safety and effectiveness of these remedies have been poorly evaluated. The aim of this study was to evaluate the antibacterial properties of these remedies against seven gram-positive and gram-negative multidrug-resistant bacteria species. Phytochemical constituents and cytotoxicity of these remedies were also determined. Seven remedies, consisting of Um-Ma-Luk-Ka-Wa-Tee, Chan-Ta-Lee-La, Kheaw-Hom, Learng-Pid-Sa-Mud, Pra-Sa-Chan-Dang, Dhart-Ban-Chob, and Tree-Hom, were prepared by a licensed traditional medical doctor using a mixture of medicinal plants. Antibacterial activity of ethanol extracts of the remedies was determined by using a broth microdilution method. Qualitative phytochemical screening analysis was carried out to identify the presence of major components. Cytotoxicity activities of the extracts against Vero cells were assessed by green fluorescent protein-based assay. With the exception of Dhart-Ban-Chob extract, significant minimum inhibitory concentrations (MICs) of <16 to 32 μg/mL were observed for the remedy extracts depending on the bacterial strains. The Um-Ma-Luk-Ka-Wa-Tee extract was noncytotoxic against Vero cells and possessed the highest activity, with MICs of <16 to 31 μg/mL against all methicillin-resistant Staphylococcus aureus isolates. Remarkable antibacterial activities against multidrug-resistant pathogens, as well as low toxicity on Vero cells, of Um-Ma-Luk-Ka-Wa-Tee support the use of this remedy in traditional medicine. Further investigation on other biological activities related to traditional applications, appropriate biomarkers, and treatment mechanisms of the household remedy are required.

Evaluation of Antibacterial Activity, Phytochemical Constituents, and Cytotoxicity Effects of Thai Household Ancient Remedies

PubMed Central

Sinvaraphan, Naruephan; Chaipak, Ploypailin; Luxsananuwong, Atita; Voravuthikunchai, Supayang Piyawan

2014-01-01

Abstract Aim: Household ancient remedies reported here are described in the National List of Essential Medicines and have traditionally been used in Thailand to treat infection-related ailments. However, the safety and effectiveness of these remedies have been poorly evaluated. The aim of this study was to evaluate the antibacterial properties of these remedies against seven gram-positive and gram-negative multidrug-resistant bacteria species. Phytochemical constituents and cytotoxicity of these remedies were also determined. Methods: Seven remedies, consisting of Um-Ma-Luk-Ka-Wa-Tee, Chan-Ta-Lee-La, Kheaw-Hom, Learng-Pid-Sa-Mud, Pra-Sa-Chan-Dang, Dhart-Ban-Chob, and Tree-Hom, were prepared by a licensed traditional medical doctor using a mixture of medicinal plants. Antibacterial activity of ethanol extracts of the remedies was determined by using a broth microdilution method. Qualitative phytochemical screening analysis was carried out to identify the presence of major components. Cytotoxicity activities of the extracts against Vero cells were assessed by green fluorescent protein–based assay. Results: With the exception of Dhart-Ban-Chob extract, significant minimum inhibitory concentrations (MICs) of <16 to 32 μg/mL were observed for the remedy extracts depending on the bacterial strains. The Um-Ma-Luk-Ka-Wa-Tee extract was noncytotoxic against Vero cells and possessed the highest activity, with MICs of <16 to 31 μg/mL against all methicillin-resistant Staphylococcus aureus isolates. Conclusions: Remarkable antibacterial activities against multidrug-resistant pathogens, as well as low toxicity on Vero cells, of Um-Ma-Luk-Ka-Wa-Tee support the use of this remedy in traditional medicine. Further investigation on other biological activities related to traditional applications, appropriate biomarkers, and treatment mechanisms of the household remedy are required. PMID:25415453

Incidence and Clinical Features of Early Stent Thrombosis in the Era of New P2y12 Inhibitors (PLATIS-2)

PubMed Central

Asher, Elad; Abu-Much, Arsalan; Goldenberg, Ilan; Segev, Amit; Sabbag, Avi; Mazin, Israel; Shlezinger, Meital; Atar, Shaul; Zahger, Doron; Polak, Arthur; Beigel, Roy; Matetzky, Shlomi

2016-01-01

Early stent thrombosis (EST) (≤ 30 days after stent implantation) is a relatively rare but deleterious complication of percutaneous coronary intervention (PCI). Administration of newer P2Y12 inhibitors (prasugrel and ticagrelor) combined with aspirin has been shown to reduce the incidence of sub-acute and late stent thrombosis, compared with clopidogrel. We investigated the “real life” incidence of EST in patients from a large acute coronary syndrome (ACS) national registry, where newer P2Y12 inhibitors are widely used. Patients were derived from the ACS Israeli Survey (ACSIS), conducted during 2006, 2008, 2010 and 2013. Major adverse cardiac events (MACE) at 30days were defined as all-cause death, recurrent ACS, EST and stroke.Of the 4717 ACS patients who underwent PCI and stenting, 83% received clopidogrel and 17% newer P2Y12 inhibitors. The rate of EST was similar in both groups (1.7% in the newer P2Y12 inhibitor group vs. 1.4% in the clopidogrel-treated patients, p = 0.42). Results were consistent after multivariate analysis (adjusted HR = 1.06 [p = 0.89]). MACE occurred in 6.4% in the newer P2Y12 inhibitor group compared with 9.2% in the clopidogrel group (P<0.01). However, multivariate logistic regression modeling showed that treatment with newer P2Y12 inhibitors was not significantly associated with the secondary endpoint of MACE when compared with clopidogrel therapy [OR = 1.26 95%CI (0.93–1.73), P = 0.136]. The incidence of "real life" EST at 1month is relatively low, and appears to be similar in patients who receive newer P2Y12 inhibitors as well as in those who receive clopidogrel. PMID:27310147

Incidence and Clinical Features of Early Stent Thrombosis in the Era of New P2y12 Inhibitors (PLATIS-2).

PubMed

Asher, Elad; Abu-Much, Arsalan; Goldenberg, Ilan; Segev, Amit; Sabbag, Avi; Mazin, Israel; Shlezinger, Meital; Atar, Shaul; Zahger, Doron; Polak, Arthur; Beigel, Roy; Matetzky, Shlomi

2016-01-01

Early stent thrombosis (EST) (≤ 30 days after stent implantation) is a relatively rare but deleterious complication of percutaneous coronary intervention (PCI). Administration of newer P2Y12 inhibitors (prasugrel and ticagrelor) combined with aspirin has been shown to reduce the incidence of sub-acute and late stent thrombosis, compared with clopidogrel. We investigated the "real life" incidence of EST in patients from a large acute coronary syndrome (ACS) national registry, where newer P2Y12 inhibitors are widely used. Patients were derived from the ACS Israeli Survey (ACSIS), conducted during 2006, 2008, 2010 and 2013. Major adverse cardiac events (MACE) at 30days were defined as all-cause death, recurrent ACS, EST and stroke.Of the 4717 ACS patients who underwent PCI and stenting, 83% received clopidogrel and 17% newer P2Y12 inhibitors. The rate of EST was similar in both groups (1.7% in the newer P2Y12 inhibitor group vs. 1.4% in the clopidogrel-treated patients, p = 0.42). Results were consistent after multivariate analysis (adjusted HR = 1.06 [p = 0.89]). MACE occurred in 6.4% in the newer P2Y12 inhibitor group compared with 9.2% in the clopidogrel group (P<0.01). However, multivariate logistic regression modeling showed that treatment with newer P2Y12 inhibitors was not significantly associated with the secondary endpoint of MACE when compared with clopidogrel therapy [OR = 1.26 95%CI (0.93-1.73), P = 0.136]. The incidence of "real life" EST at 1month is relatively low, and appears to be similar in patients who receive newer P2Y12 inhibitors as well as in those who receive clopidogrel.

Assessing the trend in sustainable remediation: A questionnaire survey of remediation professionals in various countries.

PubMed

Hou, Deyi; Guthrie, Peter; Rigby, Mark

2016-12-15

Over the past decade, sustainable remediation has grown from an emerging concept into a widely accepted new institutional norm. Scholar literature increased exponentially from nearly none in late 1990s to over 400 publications per year in 2014. The present study used a questionnaire survey conducted in 2012 and 2014 to assess the global trend in the awareness and practice of sustainable remediation. A total of 373 responses were received from survey participants located in 22 countries. The survey found that the US and the UK similarly had the highest level of awareness and adoption rate of sustainable remediation. Asia and other developing countries had much lower awareness levels and/or adoption rates. For all regions, the adoption rates were significantly lower than awareness levels, indicating a large gap between awareness and practice. One specific example is regarding minimizing greenhouse gas emission, which is a focal point in sustainable remediation literature, but with very low adoption rate according to this survey. This study also found that the adoption rates of a few sustainable remediation considerations, such as "minimizing local scale secondary impact", "minimizing national to global scale secondary impact", and "bringing prosperity to disadvantaged community", had decreased between 2012 and 2014. On the other hand, the survey also suggests the remediation community has rendered more expertise, training, and resources in sustainable remediation between 2012 and 2014. The mixed results suggest that in order to enhance sustainable remediation adoption, it is imperative to employ continued effort to enhance the understanding of sustainable remediation by practitioners and to link self-interest and public interest with sustainable remediation considerations. Copyright © 2016 Elsevier Ltd. All rights reserved.

Integrating remediation and resource recovery: On the economic conditions of landfill mining

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frändegård, Per, E-mail: per.frandegard@liu.se; Krook, Joakim; Svensson, Niclas

Highlights: • We compare two remediation scenarios; one with resource recovery and one without. • Economic analysis includes relevant direct costs and revenues for the landfill owner. • High degrees of metal and/or combustible contents are important economic factors. • Landfill tax and the access to a CHP can have a large impact on the result. • Combining landfill mining and remediation may decrease the project cost. - Abstract: This article analyzes the economic potential of integrating material separation and resource recovery into a landfill remediation project, and discusses the result and the largest impact factors. The analysis is donemore » using a direct costs/revenues approach and the stochastic uncertainties are handled using Monte Carlo simulation. Two remediation scenarios are applied to a hypothetical landfill. One scenario includes only remediation, while the second scenario adds resource recovery to the remediation project. Moreover, the second scenario is divided into two cases, case A and B. In case A, the landfill tax needs to be paid for re-deposited material and the landfill holder does not own a combined heat and power plant (CHP), which leads to disposal costs in the form of gate fees. In case B, the landfill tax is waived on the re-deposited material and the landfill holder owns its own CHP. Results show that the remediation project in the first scenario costs about €23/ton. Adding resource recovery as in case A worsens the result to −€36/ton, while for case B the result improves to −€14/ton. This shows the importance of landfill tax and the access to a CHP. Other important factors for the result are the material composition in the landfill, the efficiency of the separation technology used, and the price of the saleable material.« less

Two LNG plants slated for Indonesia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parker, R.F.; Phannenstiel, L.L.

1975-06-09

Two large LNG plants are in the planning stage for Indonesia. The Badak field in East Kalimantan, Borneo, will have a 450 million ft/sup 3//day plant with a projected 20-y life. Gas will be liquefied in a 2-train plant employing the propane-MCR process, then stored in double-wall tanks having a total capacity of 2.4 million bbl. Arun field in North Sumatra will have an LNG plant capable of liquefying 1.2 billion ft/sup 3//day of gas in 6 trains, also using the propane-MCR process. LNG storage capacity at Arun will total 3.2 million bbl.

Resource Conservation and Recovery Act (RCRA) Part B permit application for tank storage units at the Oak Ridge Y-12 Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-05-01

In compliance with the Resource Conservation and Recovery Act (RCRA), this report discusses information relating to permit applications for three tank storage units at Y-12. The storage units are: Building 9811-1 RCRA Tank Storage Unit (OD-7); Waste Oil/Solvent Storage Unit (OD-9); and Liquid Organic Solvent Storage Unit (OD-10). Numerous sections discuss the following: Facility description; waste characteristics; process information; groundwater monitoring; procedures to prevent hazards; contingency plan; personnel training; closure plan, post closure plan, and financial requirements; record keeping; other federal laws; organic air emissions; solid waste management units; and certification. Sixteen appendices contain such items as maps, waste analysesmore » and forms, inspection logs, equipment identification, etc.« less

45 CFR 1303.4 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 4 2011-10-01 2011-10-01 false Remedies. 1303.4 Section 1303.4 Public Welfare... PROCEDURES FOR HEAD START GRANTEES AND CURRENT OR PROSPECTIVE DELEGATE AGENCIES General § 1303.4 Remedies... from pursuing any other remedies authorized by law. ...

Remediation plans in family medicine residency

PubMed Central

Audétat, Marie-Claude; Voirol, Christian; Béland, Normand; Fernandez, Nicolas; Sanche, Gilbert

2015-01-01

Abstract Objective To assess use of the remediation instrument that has been implemented in training sites at the University of Montreal in Quebec to support faculty in diagnosing and remediating resident academic difficulties, to examine whether and how this particular remediation instrument improves the remediation process, and to determine its effects on the residents’ subsequent rotation assessments. Design A multimethods approach in which data were collected from different sources: remediation plans developed by faculty, program statistics for the corresponding academic years, and students’ academic records and rotation assessment results. Setting Family medicine residency program at the University of Montreal. Participants Family medicine residents in academic difficulty. Main outcome measures Assessment of the content, process, and quality of remediation plans, and students’ academic and rotation assessment results (successful, below expectations, or failure) both before and after the remediation period. Results The framework that was developed for assessing remediation plans was used to analyze 23 plans produced by 10 teaching sites for 21 residents. All plans documented cognitive problems and implemented numerous remediation measures. Although only 48% of the plans were of good quality, implementation of a remediation plan was positively associated with the resident’s success in rotations following the remediation period. Conclusion The use of remediation plans is well embedded in training sites at the University of Montreal. The residents’ difficulties were mainly cognitive in nature, but this generally related to deficits in clinical reasoning rather than knowledge gaps. The reflection and analysis required to produce a remediation plan helps to correct many academic difficulties and normalize the academic career of most residents in difficulty. Further effort is still needed to improve the quality of plans and to support teachers.

48 CFR 1303.906 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Remedies. 1303.906 Section... Remedies. The designee authorized to determine whether a contractor has subjected an employee to reprisal and to determine the appropriate remedy is set forth in CAM 1301.70. ...

48 CFR 1303.906 - Remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Remedies. 1303.906 Section... Remedies. The designee authorized to determine whether a contractor has subjected an employee to reprisal and to determine the appropriate remedy is set forth in CAM 1301.70. ...

42 CFR 488.406 - Available remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 5 2011-10-01 2011-10-01 false Available remedies. 488.406 Section 488.406 Public... Long-Term Care Facilities with Deficiencies § 488.406 Available remedies. (a) General. In addition to the remedy of termination of the provider agreement, the following remedies are available: (1...

42 CFR 488.406 - Available remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Available remedies. 488.406 Section 488.406 Public... Long-Term Care Facilities with Deficiencies § 488.406 Available remedies. (a) General. In addition to the remedy of termination of the provider agreement, the following remedies are available: (1...

Some Similarities and Differences Between Compositions Written by Remedial and Non-Remedial College Freshmen.

ERIC Educational Resources Information Center

House, Elizabeth B.; House, William J.

The essays composed by 84 remedial and 77 nonremedial college freshmen were analyzed for some features proposed by Mina Shaughnessy as being characteristic of basic writers. The students were enrolled in either a beginning remedial class (098), a class at the next level of remediation (099), or a regular English class (101). The essays were…

Protease-activated receptor-4 and purinergic receptor P2Y12 dimerize, co-internalize, and activate Akt signaling via endosomal recruitment of β-arrestin.

PubMed

Smith, Thomas H; Li, Julia G; Dores, Michael R; Trejo, JoAnn

2017-08-18

Vascular inflammation and thrombosis require the concerted actions of several different agonists, many of which act on G protein-coupled receptors (GPCRs). GPCR dimerization is a well-established phenomenon that can alter protomer function. In platelets and other cell types, protease-activated receptor-4 (PAR4) has been shown to dimerize with the purinergic receptor P2Y12 to coordinate β-arrestin-mediated Akt signaling, an important mediator of integrin activation. However, the mechanism by which the PAR4-P2Y12 dimer controls β-arrestin-dependent Akt signaling is not known. We now report that PAR4 and P2Y12 heterodimer internalization is required for β-arrestin recruitment to endosomes and Akt signaling. Using bioluminescence resonance energy transfer, immunofluorescence microscopy, and co-immunoprecipitation in cells expressing receptors exogenously and endogenously, we demonstrate that PAR4 and P2Y12 specifically interact and form dimers expressed at the cell surface. We also found that activation of PAR4 but not of P2Y12 drives internalization of the PAR4-P2Y12 heterodimer. Remarkably, activated PAR4 internalization was required for recruitment of β-arrestin to endocytic vesicles, which was dependent on co-expression of P2Y12. Interestingly, stimulation of the PAR4-P2Y12 heterodimer promotes β-arrestin and Akt co-localization to intracellular vesicles. Moreover, activated PAR4-P2Y12 internalization is required for sustained Akt activation. Thus, internalization of the PAR4-P2Y12 heterodimer is necessary for β-arrestin recruitment to endosomes and Akt signaling and lays the foundation for examining whether blockade of PAR4 internalization reduces integrin and platelet activation. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Object reasoning for waste remediation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pennock, K.A.; Bohn, S.J.; Franklin, A.L.

1991-08-01

A large number of contaminated waste sites across the United States await size remediation efforts. These sites can be physically complex, composed of multiple, possibly interacting, contaminants distributed throughout one or more media. The Remedial Action Assessment System (RAAS) is being designed and developed to support decisions concerning the selection of remediation alternatives. The goal of this system is to broaden the consideration of remediation alternatives, while reducing the time and cost of making these considerations. The Remedial Action Assessment System is a hybrid system, designed and constructed using object-oriented, knowledge- based systems, and structured programming techniques. RAAS uses amore » combination of quantitative and qualitative reasoning to consider and suggest remediation alternatives. The reasoning process that drives this application is centered around an object-oriented organization of remediation technology information. This paper describes the information structure and organization used to support this reasoning process. In addition, the paper describes the level of detail of the technology related information used in RAAS, discusses required assumptions and procedural implications of these assumptions, and provides rationale for structuring RAAS in this manner. 3 refs., 3 figs.« less

Unconventional cancer remedies.

PubMed Central

Danielson, K J; Stewart, D E; Lippert, G P

1988-01-01

Unproven and disproven remedies continue to abound for illnesses for which conventional treatment is only partially effective. This is particularly true with cancer, for which up to 50% of patients may be receiving unorthodox therapy. This article examines unconventional cancer remedies, their adverse effects, their common factors and the basis for their appeal, as well as what motivates and characterizes patients who choose these treatments. Also discussed is an approach that may be used by the conventional physician for patients who are likely to seek unorthodox treatment. This approach will help patients make the best decision about their treatment and protect them from the hazards of unconventional remedies. PMID:3285984

37 CFR 251.39 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Remedies. 251.39 Section 251.39 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION... Conduct § 251.39 Remedies. In addition to those provided above, remedies for the violation of the...

P2Y12 Polymorphisms and the Risk of Adverse Clinical Events in Patients Treated with Clopidogrel: A Meta-Analysis.

PubMed

Zhao, Kun; Yang, Ming; Lu, Yanxia; Sun, Shusen; Li, Wei; Li, Xingang; Zhao, Zhigang

2018-05-23

Some studies have reported an association between P2Y12 gene polymorphisms and clopidogrel adverse outcomes with inconsistent results. We aimed to explore the relationship between P2Y12 polymorphisms and the risk of adverse clinical events in patients treated with clopidogrel through a meta-analysis. A systematic search of PubMed, Web of Science and the Cochrane Library was conducted. Retrieved articles were comprehensively reviewed and eligible studies were included, and the relevant data was extracted for this meta-analysis. All statistical tests were performed by the Review Manager 5.3 software. A total of 14 studies involving 8,698 patients were included. In the Han Chinese population, ischemic events were associated with P2Y12 T744C polymorphism in the CC vs TT+CT genetic model (OR=3.32, 95%CI=1.62-6.82, P =0.001), and the events were associated with P2Y12 C34T polymorphism in the TT+TC vs CC genetic model (OR=1.70, 95%CI=1.22-2.36, P =0.002). However, ischemic events were not related to P2Y12 G52T polymorphism (TT+TG vs GG: OR=1.13, 95%CI=0.76-1.68, P =0.56; TT vs GG+TG: OR=2.02, 95%CI=0.65-6.28, P =0.22). The associations between the P2Y12 polymorphism and ischemic events were not significant in T744C, G52T and C34T genotype for another subgroup of the Caucasian population ( P >0.05). Only two studies referring to bleeding events were included in this analysis of C34T polymorphism, and no significant association was found (TT+TC vs CC: OR=1.07, 95%CI=0.37-3.15, P =0.90). In the Caucasian population, P2Y12 gene polymorphisms are not associated with clinical events. However, in the Chinese Han population, P2Y12 T744C and C34T polymorphisms are significantly associated with adverse clinical events. © Georg Thieme Verlag KG Stuttgart · New York.

10 CFR 205.199I - Remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 3 2011-01-01 2011-01-01 false Remedies. 205.199I Section 205.199I Energy DEPARTMENT OF... of Proposed Disallowance, and Order of Disallowance § 205.199I Remedies. (a) A Remedial Order, a... third persons for administrative expenses of effectuating appropriate remedies, and to take such other...

10 CFR 205.199I - Remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Remedies. 205.199I Section 205.199I Energy DEPARTMENT OF... of Proposed Disallowance, and Order of Disallowance § 205.199I Remedies. (a) A Remedial Order, a... third persons for administrative expenses of effectuating appropriate remedies, and to take such other...

18 CFR 706.103 - Remedial action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Remedial action. 706... RESPONSIBILITIES AND CONDUCT General Provisions § 706.103 Remedial action. (a) A violation of this part by an employee or special Government employee may be cause for remedial action. Remedial action may include, but...

18 CFR 706.103 - Remedial action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Remedial action. 706... RESPONSIBILITIES AND CONDUCT General Provisions § 706.103 Remedial action. (a) A violation of this part by an employee or special Government employee may be cause for remedial action. Remedial action may include, but...

Aerobic and anaerobic biosynthesis of nano-selenium for remediation of mercury contaminated soil.

PubMed

Wang, Xiaonan; Zhang, Daoyong; Pan, Xiangliang; Lee, Duu-Jong; Al-Misned, Fahad A; Mortuza, M Golam; Gadd, Geoffrey Michael

2017-03-01

Selenium (Se) nanoparticles are often synthesized by anaerobes. However, anaerobic bacteria cannot be directly applied for bioremediation of contaminated top soil which is generally aerobic. In this study, a selenite-reducing bacterium, Citrobacter freundii Y9, demonstrated high selenite reducing power and produced elemental nano-selenium nanoparticles (nano-Se 0 ) under both aerobic and anaerobic conditions. The biogenic nano-Se 0 converted 45.8-57.1% and 39.1-48.6% of elemental mercury (Hg 0 ) in the contaminated soil to insoluble mercuric selenide (HgSe) under anaerobic and aerobic conditions, respectively. Addition of sodium dodecyl sulfonate enhanced Hg 0 remediation, probably owing to the release of intracellular nano-Se 0 from the bacterial cells for Hg fixation. The reaction product after remediation was identified as non-reactive HgSe that was formed by amalgamation of nano-Se 0 and Hg 0 . Biosynthesis of nano-Se 0 both aerobically and anaerobically therefore provides a versatile and cost-effective remediation approach for Hg 0 -contaminated surface and subsurface soils, where the redox potential often changes dramatically. Copyright © 2016. Published by Elsevier Ltd.

Integrating remediation and resource recovery: On the economic conditions of landfill mining.

PubMed

Frändegård, Per; Krook, Joakim; Svensson, Niclas

2015-08-01

This article analyzes the economic potential of integrating material separation and resource recovery into a landfill remediation project, and discusses the result and the largest impact factors. The analysis is done using a direct costs/revenues approach and the stochastic uncertainties are handled using Monte Carlo simulation. Two remediation scenarios are applied to a hypothetical landfill. One scenario includes only remediation, while the second scenario adds resource recovery to the remediation project. Moreover, the second scenario is divided into two cases, case A and B. In case A, the landfill tax needs to be paid for re-deposited material and the landfill holder does not own a combined heat and power plant (CHP), which leads to disposal costs in the form of gate fees. In case B, the landfill tax is waived on the re-deposited material and the landfill holder owns its own CHP. Results show that the remediation project in the first scenario costs about €23/ton. Adding resource recovery as in case A worsens the result to -€36/ton, while for case B the result improves to -€14/ton. This shows the importance of landfill tax and the access to a CHP. Other important factors for the result are the material composition in the landfill, the efficiency of the separation technology used, and the price of the saleable material. Copyright © 2015 Elsevier Ltd. All rights reserved.

Highly efficient focus formation by Rous sarcoma virus on adenovirus type 12 E1A-transformed rat 3Y1 cells.

PubMed Central

Shiroki, K; Hamaguchi, M; Kawai, S

1992-01-01

When rat 3Y1 cells were infected with Rous sarcoma virus (RSV) variant SR-RSV-D(H), many 3Y1 cells acquired a stable provirus but only few of them formed transformed foci. In contrast, 12E1AY cells (3Y1 cells expressing the adenovirus type 12 [Ad12] E1A protein) formed transformed foci upon RSV infection with the same high frequency as did chicken embryo fibroblast cells. This enhancement of focus-forming efficiency was specifically observed in 3Y1 cells expressing Ad12 E1A protein but was not observed in 3Y1 cells expressing simian virus 40 T, c-myc, p53, c-fos, or v-fos protein. This enhancement was not evident in 5E1AY cells (3Y1 cells expressing the Ad5 E1A protein). Judging from the experiment using Ad12-Ad5 hybird E1A DNAs, the N-terminal half of the Ad12 E1A protein was responsible for this enhancement. The promoter activity of the RSV long terminal repeat measured by pLTR-CAT did not correlate to the efficiency of focus formation by RSV in these 3Y1 cells. Moreover, RSV containing the neo gene instead of the src gene produced G418-resistant cells equally efficiently among 3Y1, E1AY, and chicken embryo fibroblast cells. These results suggest that the enhancement of focus formation by RSV is not due to the increased expression of the src gene by the E1A protein. src mRNA and src protein were lower in RSV-transformed E1AY (RSVE1AY) cells than in RSV-transformed 3Y1 (RSV3Y1) cells. The phosphotyrosine-containing proteins were also less abundant in RSVE1AY cells than in RSV3Y1 cells, suggesting that E1AY cells require a lower threshold dose of p60v-src for transformation than do 3Y1 cells. E1AY cells were found to be more sensitive to lysis by detergents. The results suggest that the enhancement is due to changes in membrane structures in E1AY cells. Images PMID:1310757

Tissue kallikrein induces SH-SY5Y cell proliferation via epidermal growth factor receptor and extracellular signal-regulated kinase1/2 pathway

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lu, Zhengyu; Department of Neurology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437; Yang, Qi

2014-03-28

Highlights: • TK promotes EGFR phosphorylation in SH-SY5Y cells. • TK activates ERK1/2 and p38 phosphorylation in SH-SY5Y cells. • TK mediates SH-SY5Y cell proliferation via EGFR and ERK1/2 pathway. - Abstract: Tissue kallikrein (TK) is well known to take most of its biological functions through bradykinin receptors. In the present study, we found a novel signaling pathway mediated by TK through epidermal growth factor receptor (EGFR) in human SH-SY5Y cells. We discovered that TK facilitated the activation of EGFR, extracellular signal-regulated kinase (ERK) 1/2 and p38 cascade. Interestingly, not p38 but ERK1/2 phosphorylation was severely compromised in cells depletedmore » of EGFR. Nevertheless, impairment of signaling of ERK1/2 seemed not to be restricted to EGFR phosphorylation. We also observed that TK stimulation could induce SH-SY5Y cell proliferation, which was reduced by EGFR down-regulation or ERK1/2 inhibitor. Overall, our findings provided convincing evidence that TK could mediate cell proliferation via EGFR and ERK1/2 pathway in vitro.« less

39 CFR 927.3 - Other remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Other remedies. 927.3 Section 927.3 Postal Service... § 927.3 Other remedies. The procedures and other requirements of this part apply only where the Postal... remedies available to the Postal Service, including such remedies as summary action to withhold tender of...

39 CFR 927.3 - Other remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Other remedies. 927.3 Section 927.3 Postal Service... § 927.3 Other remedies. The procedures and other requirements of this part apply only where the Postal... remedies available to the Postal Service, including such remedies as summary action to withhold tender of...

Air-Based Remediation Workshop - Section 7 Sustainable Remediation And Air-Based Technologies

EPA Science Inventory

Pursuant to the EPA-AIT Implementing Arrangement 7 for Technical Environmental Collaboration, Activity 11 "Remediation of Contaminated Sites, " the USEPA Office of International Affairs Organized a Forced Air Remediation Workshop in Taipei to deliver expert training to the Enviro...

Air-Based Remediation Workshop - Section 8 Air-Based Remediation Technology Selection Logic

EPA Science Inventory

Pursuant to the EPA-AIT Implementing Arrangement 7 for Technical Environmental Collaboration, Activity 11 "Remediation of Contaminated Sites," the USEPA Office of International Affairs Organized a Forced Air Remediation Workshop in Taipei to deliver expert training to the Environ...

Nanoparticle-Encapsulated Curcumin Inhibits Diabetic Neuropathic Pain Involving the P2Y12 Receptor in the Dorsal Root Ganglia

PubMed Central

Jia, Tianyu; Rao, Jingan; Zou, Lifang; Zhao, Shanhong; Yi, Zhihua; Wu, Bing; Li, Lin; Yuan, Huilong; Shi, Liran; Zhang, Chunping; Gao, Yun; Liu, Shuangmei; Xu, Hong; Liu, Hui; Liang, Shangdong; Li, Guilin

2018-01-01

Diabetic peripheral neuropathy results in diabetic neuropathic pain (DNP). Satellite glial cells (SGCs) enwrap the neuronal soma in the dorsal root ganglia (DRG). The purinergic 2 (P2) Y12 receptor is expressed on SGCs in the DRG. SGC activation plays an important role in the pathogenesis of DNP. Curcumin has anti-inflammatory and antioxidant properties. Because curcumin has poor metabolic stability in vivo and low bioavailability, nanoparticle-encapsulated curcumin was used to improve its targeting and bioavailability. In the present study, our aim was to investigate the effects of nanoparticle-encapsulated curcumin on DNP mediated by the P2Y12 receptor on SGCs in the rat DRG. Diabetic peripheral neuropathy increased the expression levels of the P2Y12 receptor on SGCs in the DRG and enhanced mechanical and thermal hyperalgesia in rats with diabetes mellitus (DM). Up-regulation of the P2Y12 receptor in SGCs in the DRG increased the production of pro-inflammatory cytokines. Up-regulation of interleukin-1β (IL-1β) and connexin43 (Cx43) resulted in mechanical and thermal hyperalgesia in rats with DM. The nanoparticle-encapsulated curcumin decreased up-regulated IL-1β and Cx43 expression and reduced levels of phosphorylated-Akt (p-Akt) in the DRG of rats with DM. The up-regulation of P2Y12 on SGCs and the up-regulation of the IL-1β and Cx43 in the DRG indicated the activation of SGCs in the DRG. The nano-curcumin treatment inhibited the activation of SGCs accompanied by its anti-inflammatory effect to decrease the up-regulated CGRP expression in the DRG neurons. Therefore, the nanoparticle-encapsulated curcumin treatment decreased the up-regulation of the P2Y12 receptor on SGCs in the DRG and decreased mechanical and thermal hyperalgesia in rats with DM. PMID:29422835

4 CFR 21.8 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 4 Accounts 1 2011-01-01 2011-01-01 false Remedies. 21.8 Section 21.8 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES BID PROTEST REGULATIONS § 21.8 Remedies. (a) If GAO determines that a... following remedies: (1) Refrain from exercising options under the contract; (2) Terminate the contract; (3...

49 CFR 604.47 - Remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 7 2010-10-01 2010-10-01 false Remedies. 604.47 Section 604.47 Transportation... TRANSPORTATION CHARTER SERVICE Hearings. § 604.47 Remedies. (a) If the Chief Counsel determines that a violation..., its employees, or its contractors. (b) In determining the type and amount of remedy, the Chief Counsel...

4 CFR 21.8 - Remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Remedies. 21.8 Section 21.8 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES BID PROTEST REGULATIONS § 21.8 Remedies. (a) If GAO determines that a... following remedies: (1) Refrain from exercising options under the contract; (2) Terminate the contract; (3...

49 CFR 604.47 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 7 2011-10-01 2011-10-01 false Remedies. 604.47 Section 604.47 Transportation... TRANSPORTATION CHARTER SERVICE Hearings. § 604.47 Remedies. (a) If the Chief Counsel determines that a violation..., its employees, or its contractors. (b) In determining the type and amount of remedy, the Chief Counsel...

Supporting evaluation for the proposed plan for final remedial action for the groundwater operable unit at the chemical plant area of the Weldon Spring Site, Weldon Spring, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2003-08-06

This report presents the technical information developed since the interim record of decision (IROD) was issued in September 2000 (U.S. Department of Energy [DOE] 2000). The information was incorporated into the evaluation that was performed in selecting the preferred alternative for the Chemical Plant groundwater operable unit (GWOU) of the Weldon Spring site. The contaminants of concern (COCs) in groundwater and springs are trichloroethylene (TCE), nitrate, uranium, and nitroaromatic compounds. The preferred alternative of monitored natural attenuation (MNA) coupled with institutional controls (ICs) and contingency activities is described in the ''Proposed Plan (PP) for Final Remedial Action for the Groundwatermore » Operable Unit at the Chemical Plant Area of the Weldon Spring Site, Weldon Spring, Missouri'' (DOE 2003b).« less

ORNL Remedial Action Program strategy (FY 1987-FY 1992)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trabalka, J.R.; Myrick, T.E.

1987-12-01

Over 40 years of Oak Ridge National Laboratory (ORNL) operations have produced a diverse legacy of contaminated inactive facilities, research areas, and waste disposal areas that are potential candidates for remedial action. The ORNL Remedial Action Program (RAP) represents a comprehensive effort to meet new regulatory requirements and ensure adequate protection of on-site workers, the public, and the environment by providing appropriate corrective measures at over 130 sites contaminated historically with radioactive, hazardous chemical, or mixed wastes. A structured path of program planning, site characterization, alternatives assessment, technology development, engineering design, continued site maintenance and surveillance, interim corrective action, andmore » eventual site closure or decommissioning is required to meet these objectives. This report documents the development of the Remedial Action Program, through its preliminary characterization, regulatory interface, and strategy development activities. It provides recommendations for a comprehensive, long-term strategy consistent with existing technical, institutional, and regulatory information, along with a six-year plan for achieving its initial objectives. 53 refs., 8 figs., 12 tabs.« less

High sensitivity 1H-NMR spectroscopy of homeopathic remedies made in water

PubMed Central

Anick, David J

2004-01-01

Background The efficacy of homeopathy is controversial. Homeopathic remedies are made via iterated shaking and dilution, in ethanol or in water, from a starting substance. Remedies of potency 12 C or higher are ultra-dilute (UD), i.e. contain zero molecules of the starting material. Various hypotheses have been advanced to explain how a UD remedy might be different from unprepared solvent. One such hypothesis posits that a remedy contains stable clusters, i.e. localized regions where one or more hydrogen bonds remain fixed on a long time scale. High sensitivity proton nuclear magnetic resonance spectroscopy has not previously been used to look for evidence of differences between UD remedies and controls. Methods Homeopathic remedies made in water were studied via high sensitivity proton nuclear magnetic resonance spectroscopy. A total of 57 remedy samples representing six starting materials and spanning a variety of potencies from 6 C to 10 M were tested along with 46 controls. Results By presaturating on the water peak, signals could be reliably detected that represented H-containing species at concentrations as low as 5 μM. There were 35 positions where a discrete signal was seen in one or more of the 103 spectra, which should theoretically have been absent from the spectrum of pure water. Of these 35, fifteen were identified as machine-generated artifacts, eight were identified as trace levels of organic contaminants, and twelve were unexplained. Of the unexplained signals, six were seen in just one spectrum each. None of the artifacts or unexplained signals occurred more frequently in remedies than in controls, using a p < .05 cutoff. Some commercially prepared samples were found to contain traces of one or more of these small organic molecules: ethanol, acetate, formate, methanol, and acetone. Conclusion No discrete signals suggesting a difference between remedies and controls were seen, via high sensitivity 1H-NMR spectroscopy. The results failed to support

39 CFR 3030.50 - Remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Remedies. 3030.50 Section 3030.50 Postal Service....50 Remedies. (a) If the Commission finds that a complaint is justified, it will order that the Postal... applicable requirements; and (2) Remedy the effects of any non-compliance. (b) If the Commission finds...

39 CFR 3030.50 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Remedies. 3030.50 Section 3030.50 Postal Service....50 Remedies. (a) If the Commission finds that a complaint is justified, it will order that the Postal... applicable requirements; and (2) Remedy the effects of any non-compliance. (b) If the Commission finds...

Meningiomas del foramen magno: Reporte de 12 casos y revisión de la literatura

PubMed Central

Campero, Álvaro; Ajler, Pablo; Roman, Guillermo; Rivadeneira, Conrado

2017-01-01

Resumen Objetivo: El propósito del presente trabajo es presentar los resultados de 12 pacientes con diagnóstico de meningiomas del foramen magno (MFM), de localización anterior o lateral, operados con técnicas microquirúrgicas. Método: Desde Junio de 2005 a Diciembre de 2016, 12 pacientes con diagnóstico de MFM fueron intervenidos quirúrgicamente. Se evaluó: edad, sexo, localización de la lesión (anterior o lateral), sintomatología, tipo de abordaje utilizado y resultados postoperatorios. Resultados: De los pacientes intervenidos, 8 fueron mujeres y 4 varones. La edad promedio fue de 47 años. La localización fue anterior en 8 casos y lateral en 4 casos. La sintomatología más frecuente fue dolor occipito-cervical (8 casos), seguido de tetraparesia (3 casos). En los pacientes con MFM de localización anterior se realizó un abordaje extremo-lateral transcondilar (ELTC), mientras que en los tumores laterales el abordaje fue extremo-lateral retrocondilar (ELRC). En 10 casos la resección fue completa. En dos pacientes fue necesario dejar una pequeña lámina de meningioma sobre la arteria vertebral y a nivel del foramen yugular. Como complicaciones postoperatorias, 3 pacientes presentaron una paresia del XII nervio craneano y 2 pacientes paresia del XI nervio craneano; además, 1 paciente presentó una fístula de LCR. Conclusión: La cirugía de los MFM de localización anterior y lateral puede ser realizada de forma segura y efectiva. Es necesario: a) buen conocimiento anatómico de la región; b) disecar los músculos de la nuca en 2 planos, exponiendo el triángulo suboccipital y la arteria vertebral (AV); 3) realizar un abordaje ELRC en los tumores laterales, y ELTC en los tumores anteriores; y 4) buena técnica microquirúrgica. PMID:29142778

Accumulation of Hydrocarbons by Maize (Zea mays L.) in Remediation of Soils Contaminated with Crude Oil.

PubMed

Liao, Changjun; Xu, Wending; Lu, Guining; Liang, Xujun; Guo, Chuling; Yang, Chen; Dang, Zhi

2015-01-01

This study has investigated the use of screened maize for remediation of soil contaminated with crude oil. Pots experiment was carried out for 60 days by transplanting maize seedlings into spiked soils. The results showed that certain amount of crude oil in soil (≤2 147 mg·kg(-1)) could enhance the production of shoot biomass of maize. Higher concentration (6 373 mg·kg(-1)) did not significantly inhibit the growth of plant maize (including shoot and root). Analysis of plant shoot by GC-MS showed that low molecular weight polycyclic aromatic hydrocarbons (PAHs) were detected in maize tissues, but PAHs concentration in the plant did not increase with higher concentration of crude oil in soil. The reduction of total petroleum hydrocarbon in planted soil was up to 52.21-72.84%, while that of the corresponding controls was only 25.85-34.22% in two months. In addition, data from physiological and biochemical indexes demonstrated a favorable adaptability of maize to crude oil pollution stress. This study suggested that the use of maize (Zea mays L.) was a good choice for remediation of soil contaminated with petroleum within a certain range of concentrations.

Modernization at the Y-12 National Security Complex: A Case for Additional Experimental Benchmarks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thornbury, M. L.; Juarez, C.; Krass, A. W.

Efforts are underway at the Y-12 National Security Complex (Y-12) to modernize the recovery, purification, and consolidation of un-irradiated, highly enriched uranium metal. Successful integration of advanced technology such as Electrorefining (ER) eliminates many of the intermediate chemistry systems and processes that are the current and historical basis of the nuclear fuel cycle at Y-12. The cost of operations, the inventory of hazardous chemicals, and the volume of waste are significantly reduced by ER. It also introduces unique material forms and compositions related to the chemistry of chloride salts for further consideration in safety analysis and engineering. The work hereinmore » briefly describes recent investigations of nuclear criticality for 235UO2Cl2 (uranyl chloride) and 6LiCl (lithium chloride) in aqueous solution. Of particular interest is the minimum critical mass of highly enriched uranium as a function of the molar ratio of 6Li to 235U. The work herein also briefly describes recent investigations of nuclear criticality for 235U metal reflected by salt mixtures of 6LiCl or 7LiCl (lithium chloride), KCl (potassium chloride), and 235UCl3 or 238UCl3 (uranium tri-chloride). Computational methods for analysis of nuclear criticality safety and published nuclear data are employed in the absence of directly relevant experimental criticality benchmarks.« less

48 CFR 203.906 - Remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Remedies. 203.906 Section... for Contractor Employees 203.906 Remedies. (1) Not later than 30 days after receiving a DoD Inspector... administrative remedies with respect to the complaint; and (ii) The complainant may bring a de novo action at law...