Sample records for ydfa-based booster amplifier

  1. Fiber Optical Parametric Oscillator for High Power, High Efficiency Short-Wavelength Generation

    DTIC Science & Technology

    2010-12-05

    the spectral region about 1550 nm, this project has explored the possibility of using ytterbium - doped fiber lasers (YDFL) and amplifiers (YDFA) as...integration. From this point of view, an ytterbium - doped fiber -based pump source looks most attractive. Of particular interest is the master- oscillator... ytterbium - doped fiber amplifiers (YDFA). The MOPA constructed for this work is shown in Figure 1. It consists of a CW fiber ring-laser centered at

  2. Energy-signal quality trade-offs in a WiMAX mobile station with a booster amplifier

    NASA Astrophysics Data System (ADS)

    Suherman; Mubarakah, N.; Wiranata, O.; Kasim, S. T.

    2018-02-01

    Worldwide Interoperability for Microwave Access (WiMAX) is a broadband wireless access technology that is able to provide high bit rate mobile internet services. Battery endurance remains a problem in current mobile communication. On the other hand, signal quality determines the successful run of the mobile applications. Energy consumption optimization cannot sacrifice the signal level required by the application to run smoothly. On the contrary, the application should consider battery life time. This paper examines the tradeoffs between energy and signal quality in WiMAX subscriber station by adjusting signal level using a booster amplifier. Simulation evaluations show that an increment of 0.00000104% energy consumption on using amplifier adaptively produces 16.411% signal to noise ratio (SNR) increment and 10.7% bit error rate (BER) decrement. By keeping the amplifier turned on, energy consumption increases up to 0.00000136%, causing the SNR rises to 17.2638% and BER drops to 11.13%. The evaluated application is video streaming, other application may behave differently.

  3. Emulsion based cast booster - a priming system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gupta, R.N.; Mishra, A.K.

    2005-07-01

    This paper explores the potential of emulsion based cast booster to be used as primer to initiate bulk delivered emulsion explosives used in mines. An attempt has been made for comparative study between conventional cast booster and emulsion based cast booster in terms of the initiation process developed and their capability to develop and maintain the stable detonation process in the column explosives. The study has been conducted using a continuous velocity of detonation (VOD) measuring instrument. During this study three blasts have been monitored. In each blast two holes have been selected for study, the first hole being initiatedmore » with conventional cast booster while the other one with emulsion based cast booster. The findings of the study advocates that emulsion based cast booster is capable of efficient priming of bulk delivered column explosive with stable detonation process in the column. Further, the booster had advantages over the conventional PETN/TNT based cast booster. 5 refs., 2 figs., 1 tab., 1 photo.« less

  4. Compact nanosecond laser system for the ignition of aeronautic combustion engines

    NASA Astrophysics Data System (ADS)

    Amiard-Hudebine, G.; Tison, G.; Freysz, E.

    2016-12-01

    We have studied and developed a compact nanosecond laser system dedicated to the ignition of aeronautic combustion engines. This system is based on a nanosecond microchip laser delivering 6 μJ nanosecond pulses, which are amplified in two successive stages. The first stage is based on an Ytterbium doped fiber amplifier (YDFA) working in a quasi-continuous-wave (QCW) regime. Pumped at 1 kHz repetition rate, it delivers TEM00 and linearly polarized nanosecond pulses centered at 1064 nm with energies up to 350 μJ. These results are in very good agreement with the model we specially designed for a pulsed QCW pump regime. The second amplification stage is based on a compact Nd:YAG double-pass amplifier pumped by a 400 W peak power QCW diode centered at λ = 808 nm and coupled to a 800 μm core multimode fiber. At 10 Hz repetition rate, this system amplifies the pulse delivered by the YDFA up to 11 mJ while preserving its beam profile, polarization ratio, and pulse duration. Finally, we demonstrate that this compact nanosecond system can ignite an experimental combustion chamber.

  5. Amplified OTDR systems for multipoint corrosion monitoring.

    PubMed

    Nascimento, Jehan F; Silva, Marcionilo J; Coêlho, Isnaldo J S; Cipriano, Eliel; Martins-Filho, Joaquim F

    2012-01-01

    We present two configurations of an amplified fiber-optic-based corrosion sensor using the optical time domain reflectometry (OTDR) technique as the interrogation method. The sensor system is multipoint, self-referenced, has no moving parts and can measure the corrosion rate several kilometers away from the OTDR equipment. The first OTDR monitoring system employs a remotely pumped in-line EDFA and it is used to evaluate the increase in system reach compared to a non-amplified configuration. The other amplified monitoring system uses an EDFA in booster configuration and we perform corrosion measurements and evaluations of system sensitivity to amplifier gain variations. Our experimental results obtained under controlled laboratory conditions show the advantages of the amplified system in terms of longer system reach with better spatial resolution, and also that the corrosion measurements obtained from our system are not sensitive to 3 dB gain variations.

  6. Amplified OTDR Systems for Multipoint Corrosion Monitoring

    PubMed Central

    Nascimento, Jehan F.; Silva, Marcionilo J.; Coêlho, Isnaldo J. S.; Cipriano, Eliel; Martins-Filho, Joaquim F.

    2012-01-01

    We present two configurations of an amplified fiber-optic-based corrosion sensor using the optical time domain reflectometry (OTDR) technique as the interrogation method. The sensor system is multipoint, self-referenced, has no moving parts and can measure the corrosion rate several kilometers away from the OTDR equipment. The first OTDR monitoring system employs a remotely pumped in-line EDFA and it is used to evaluate the increase in system reach compared to a non-amplified configuration. The other amplified monitoring system uses an EDFA in booster configuration and we perform corrosion measurements and evaluations of system sensitivity to amplifier gain variations. Our experimental results obtained under controlled laboratory conditions show the advantages of the amplified system in terms of longer system reach with better spatial resolution, and also that the corrosion measurements obtained from our system are not sensitive to 3 dB gain variations. PMID:22737017

  7. Space shuttle booster multi-engine base flow analysis

    NASA Technical Reports Server (NTRS)

    Tang, H. H.; Gardiner, C. R.; Anderson, W. A.; Navickas, J.

    1972-01-01

    A comprehensive review of currently available techniques pertinent to several prominent aspects of the base thermal problem of the space shuttle booster is given along with a brief review of experimental results. A tractable engineering analysis, capable of predicting the power-on base pressure, base heating, and other base thermal environmental conditions, such as base gas temperature, is presented and used for an analysis of various space shuttle booster configurations. The analysis consists of a rational combination of theoretical treatments of the prominent flow interaction phenomena in the base region. These theories consider jet mixing, plume flow, axisymmetric flow effects, base injection, recirculating flow dynamics, and various modes of heat transfer. Such effects as initial boundary layer expansion at the nozzle lip, reattachment, recompression, choked vent flow, and nonisoenergetic mixing processes are included in the analysis. A unified method was developed and programmed to numerically obtain compatible solutions for the various flow field components in both flight and ground test conditions. Preliminary prediction for a 12-engine space shuttle booster base thermal environment was obtained for a typical trajectory history. Theoretical predictions were also obtained for some clustered-engine experimental conditions. Results indicate good agreement between the data and theoretical predicitons.

  8. Design and prototype tests of a large-aperture 37-53 MHz ferrite-tuned booster synchrotron cavity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mark S. Champion et al.

    The Booster synchrotron at Fermilab employs eighteen 37-53 MHz ferrite-tuned double-gap coaxial radiofrequency cavities for acceleration of protons from 400 MeV to 8 GeV. The cavities have an aperture of 2.25 inches and operate at 55 kV per cavity. Future high duty factor operation of the Booster will be problematic due to unavoidable beam loss at the cavities resulting in excessive activation. The power amplifiers, high maintenance items, are mounted directly to the cavities in the tunnel. A proposed replacement for the Booster, the Proton Driver, will utilize the Booster radiofrequency cavities and requires not only a larger aperture, butmore » also higher voltage. A research and development program is underway at Fermilab to modify the Booster cavities to provide a 5-inch aperture and a 20% voltage increase. A prototype has been constructed and high power tests have bee completed. The cavity design and test results is presented.« less

  9. Cryogenic Amplifier Based Receivers at Submillimeter Wavelengths

    NASA Technical Reports Server (NTRS)

    Chattopadhyay, Goutam; Reck, Theodore and; Schlecht, Erich; Lin, Robert; Deal, William

    2012-01-01

    The operating frequency of InP high electron mobility transistor (HEMT) based amplifiers has moved well in the submillimeter-wave frequencies over the last couple of years. Working amplifiers with usable gain in waveguide packages has been reported beyond 700 GHz. When cooled cryogenically, they have shown substantial improvement in their noise temperature. This has opened up the real possibility of cryogenic amplifier based heterodyne receivers at submillimeter wavelengths for ground-based, air-borne, and space-based instruments for astrophysics, planetary, and Earth science applications. This paper provides an overview of the science applications at submillimeter wavelengths that will benefit from this technology. It also describes the current state of the InP HEMT based cryogenic amplifier receivers at submillimeter wavelengths.

  10. Progress on the Design of a Perpendicularly Biased 2nd Harmonic Cavity for the Fermilab Booster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madrak, R. L.; Dey, J. E.; Duel, K. L.

    2016-10-01

    perpendicularly biased 2nd harmonic cavity is being designed and built for the Fermilab Booster. Its purpose is to flatten the bucket at injection and thus change the longitudinal beam distribution to decrease space charge effects. It can also help at extraction. The cavity frequency range is 76 – 106 MHz. The power amplifier will be built using the Y567B tetrode, which is also used for the fundamental mode cavities in the Fermilab Booster. We discuss recent progress on the cavity, the biasing solenoid design and plans for testing the tuner's garnet material

  11. Long-term efficacy of Internet-based cognitive behavior therapy for obsessive-compulsive disorder with or without booster: a randomized controlled trial.

    PubMed

    Andersson, E; Steneby, S; Karlsson, K; Ljótsson, B; Hedman, E; Enander, J; Kaldo, V; Andersson, G; Lindefors, N; Rück, C

    2014-10-01

    As relapse after completed cognitive behavior therapy (CBT) for obsessive-compulsive disorder (OCD) is common, many treatment protocols include booster programs to improve the long-term effects. However, the effects of booster programs are not well studied. In this study, we investigated the long-term efficacy of Internet-based CBT (ICBT) with therapist support for OCD with or without an Internet-based booster program. A total of 101 participants were included in the long-term follow-up analysis of ICBT. Of these, 93 were randomized to a booster program or no booster program. Outcome assessments were collected at 4, 7, 12 and 24 months after receiving ICBT. The entire sample had sustained long-term effects from pre-treatment to all follow-up assessments, with large within-group effect sizes (Cohen's d = 1.58-2.09). The booster group had a significant mean reduction in OCD symptoms compared to the control condition from booster baseline (4 months) to 7 months, but not at 12 or 24 months. Participants in the booster group improved significantly in terms of general functioning at 7, 12 and 24 months, and had fewer relapses. Kaplan-Meier analysis also indicated a significantly slower relapse rate in the booster group. The results suggest that ICBT has sustained long-term effects and that adding an Internet-based booster program can further improve long-term outcome and prevent relapse for some OCD patients.

  12. Promoting booster seat use for young children: A school-based intervention pilot study.

    PubMed

    Bruce, Beth S; Mundle, Kim; Cramm, Camille F; Williams, Devon P

    2017-05-01

    Misuse and/or lack of booster seat use are often associated with high rates of injury and death among school-aged children. This pilot study examined the efficacy and the potential effectiveness of a booster seat intervention in the classroom. Two elementary schools participated (randomly assigned as one intervention school and one control school). At the intervention school, a certified car seat specialist and a police officer held an interactive booster seat session. The height and age for each child were recorded. Children received a certificate indicating whether they met the requirements for booster seat use and a postcard with car seat restraint specifications. Children in the control school received a brochure on car seat safety. Pre- and post-intervention self-reports were collected and booster seat use was observed. Observational findings showed a decline in booster seat use at the control school and an increase in use at the intervention school. Self-reports of booster seat use indicated a decline at both schools; however, cell sizes were too small to permit statistical analyses. Anecdotally researchers found the sessions were easy to conduct and were well received by the children and could be easily integrated into programming in schools. Classroom sessions may have the potential to positively influence booster seat use among 6- to 8-year-olds.

  13. Promoting booster seat use for young children: A school-based intervention pilot study

    PubMed Central

    Mundle, Kim; Cramm, Camille F.; Williams, Devon P.

    2017-01-01

    Abstract Purpose: Misuse and/or lack of booster seat use are often associated with high rates of injury and death among school-aged children. This pilot study examined the efficacy and the potential effectiveness of a booster seat intervention in the classroom. Methods: Two elementary schools participated (randomly assigned as one intervention school and one control school). At the intervention school, a certified car seat specialist and a police officer held an interactive booster seat session. The height and age for each child were recorded. Children received a certificate indicating whether they met the requirements for booster seat use and a postcard with car seat restraint specifications. Children in the control school received a brochure on car seat safety. Pre- and post-intervention self-reports were collected and booster seat use was observed. Results: Observational findings showed a decline in booster seat use at the control school and an increase in use at the intervention school. Self-reports of booster seat use indicated a decline at both schools; however, cell sizes were too small to permit statistical analyses. Conclusion: Anecdotally researchers found the sessions were easy to conduct and were well received by the children and could be easily integrated into programming in schools. Classroom sessions may have the potential to positively influence booster seat use among 6- to 8-year-olds. PMID:29479188

  14. Superconducting racetrack booster for the ion complex of MEIC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Filatov, Yu; Kondratenko, A. M.; Kondratenko, M. A.

    2016-02-01

    The current design of the Medium-energy Electron-Ion Collider (MEIC) project at Jefferson lab features a single 8 GeV/c figure-8 booster based on super-ferric magnets. Reducing the circumference of the booster by switching to a racetrack design may improve its performance by limiting the space charge effect and lower its cost. We consider problems of preserving proton and deuteron polarizations in a superconducting racetrack booster. We show that using magnets based on hollow high-current NbTi composite superconducting cable similar to those designed at JINR for the Nuclotron guarantees preservation of the ion polarization in a racetrack booster up to 8 GeV/c.more » The booster operation cycle would be a few seconds that would improve the operating efficiency of the MEIC ion complex.« less

  15. Role of amplified spontaneous emission in optical free-space communication links with optical amplification: impact on isolation and data transmission and utilization for pointing, acquisition, and

    NASA Astrophysics Data System (ADS)

    Winzer, Peter J.; Kalmar, Andras; Leeb, Walter R.

    1999-04-01

    We investigate the role of amplified spontaneous emission (ASE) produced by an optical booster amplifier at the transmitter of free-space optical communication links. In a communication terminal with a single telescope for both transmission and reception, this ASE power has to be taken into account in connection with transmit-to-receive channel isolation, especially since it partly occupies the same state of polarization and the same frequency band as the receive signal. We show that the booster ASE intercepted by the receiver can represent a non-negligible source of background radiation: In a typical optical intersatellite link scenario, the ASE power spectral density generated by the booster amplifier at the transmitter and coupled to the receiver will be on the order of 10-20 W/Hz, which equals the background radiation of the sun. Exploiting these findings for pointing, acquisition, and tracking (PAT) purposes, we describe a patent-pending PAT system doing without beacon lasers and without the need for diverting a part of the data signal for PAT. Utilizing the transmit booster ASE over a bandwidth of e.g. 20 nm at the receiver, a total power of about -46 dBm is available for PAT purposes without extra power consumption at the transmitter and without the need for beacon lAser alignment.

  16. MMIC DHBT Common-Base Amplifier for 172 GHz

    NASA Technical Reports Server (NTRS)

    Paidi, Vamsi; Griffith, Zack; Wei, Yun; Dahlstrom, Mttias; Urteaga, Miguel; Rodwell, Mark; Samoska, Lorene; Fung, King Man; Schlecht, Erich

    2006-01-01

    Figure 1 shows a single-stage monolithic microwave integrated circuit (MMIC) power amplifier in which the gain element is a double-heterojunction bipolar transistor (DHBT) connected in common-base configuration. This amplifier, which has been demonstrated to function well at a frequency of 172 GHz, is part of a continuing effort to develop compact, efficient amplifiers for scientific instrumentation, wide-band communication systems, and radar systems that will operate at frequencies up to and beyond 180 GHz. The transistor is fabricated from a layered structure formed by molecular beam epitaxy in the InP/InGaAs material system. A highly doped InGaAs base layer and a collector layer are fabricated from the layered structure in a triple mesa process. The transistor includes two separate emitter fingers, each having dimensions of 0.8 by 12 m. The common-base configuration was chosen for its high maximum stable gain in the frequency band of interest. The input-matching network is designed for high bandwidth. The output of the transistor is matched to a load line for maximum saturated output power under large-signal conditions, rather than being matched for maximum gain under small-signal conditions. In a test at a frequency of 172 GHz, the amplifier was found to generate an output power of 7.5 mW, with approximately 5 dB of large-signal gain (see Figure 2). Moreover, the amplifier exhibited a peak small-signal gain of 7 dB at a frequency of 176 GHz. This performance of this MMIC single-stage amplifier containing only a single transistor represents a significant advance in the state of the art, in that it rivals the 170-GHz performance of a prior MMIC three-stage, four-transistor amplifier. [The prior amplifier was reported in "MMIC HEMT Power Amplifier for 140 to 170 GHz" (NPO-30127), NASA Tech Briefs, Vol. 27, No. 11 (November 2003), page 49.] This amplifier is the first heterojunction- bipolar-transistor (HBT) amplifier built for medium power operation in this

  17. Credit BG. Interior of Deluge Water Booster Station displaying highcapacity ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. Interior of Deluge Water Booster Station displaying high-capacity electrically driven water pumps for fire fighting service - Edwards Air Force Base, North Base, Deluge Water Booster Station, Northeast of A Street, Boron, Kern County, CA

  18. Output-Based Adaptive Meshing Applied to Space Launch System Booster Separation Analysis

    NASA Technical Reports Server (NTRS)

    Dalle, Derek J.; Rogers, Stuart E.

    2015-01-01

    This paper presents details of Computational Fluid Dynamic (CFD) simulations of the Space Launch System during solid-rocket booster separation using the Cart3D inviscid code with comparisons to Overflow viscous CFD results and a wind tunnel test performed at NASA Langley Research Center's Unitary PlanWind Tunnel. The Space Launch System (SLS) launch vehicle includes two solid-rocket boosters that burn out before the primary core stage and thus must be discarded during the ascent trajectory. The main challenges for creating an aerodynamic database for this separation event are the large number of basis variables (including orientation of the core, relative position and orientation of the boosters, and rocket thrust levels) and the complex flow caused by the booster separation motors. The solid-rocket boosters are modified from their form when used with the Space Shuttle Launch Vehicle, which has a rich flight history. However, the differences between the SLS core and the Space Shuttle External Tank result in the boosters separating with much narrower clearances, and so reducing aerodynamic uncertainty is necessary to clear the integrated system for flight. This paper discusses an approach that has been developed to analyze about 6000 wind tunnel simulations and 5000 flight vehicle simulations using Cart3D in adaptive-meshing mode. In addition, a discussion is presented of Overflow viscous CFD runs used for uncertainty quantification. Finally, the article presents lessons learned and improvements that will be implemented in future separation databases.

  19. Factors Affecting Booster Seat Use.

    PubMed

    Aita-Levy, Jerussa; Henderson, Lauren

    2016-10-01

    Objective To identify general awareness of booster seats as well as reasons for use and nonuse in an urban pediatric emergency room. Methods A total of 100 questionnaires were completed consisting of 24 questions each. Questions included knowledge of booster seat guidelines, source of knowledge, awareness of risks, and confidence in booster seats. Afterward, participants were provided an educational handout. Results Majority of parents reported currently using or having used a booster seat. The most popular reason was to protect from injury (78%), and reason for nonuse was size (44%). Majority of parents agreed that motor vehicle crashes were the leading cause of death in children. However, 56% of parents prematurely transitioned child out of a booster seat. Only 20% reported learning about booster seats from their pediatrician. Conclusion Parents continue to transition their children prematurely from booster seats. Current state laws need revision as well as further education using simplified illustrated guidelines. © The Author(s) 2015.

  20. Design study of the CEPC booster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Chuang

    2014-12-10

    Design study of the CEPC booster is reported. The booster provides 120 GeV beams for the collider with topup injection frequency of 0.1 Hz. To save cost, energy of the linac injector for the booster is chosen as 6GeV, corresponding to the magnetic field of 30 Gs. In this paper, lattice of the booster is described; the low injection energy issues are studied; beam transfer from linac to booster and from booster to collider are discussed.

  1. Small-signal amplifier based on single-layer MoS2

    NASA Astrophysics Data System (ADS)

    Radisavljevic, Branimir; Whitwick, Michael B.; Kis, Andras

    2012-07-01

    In this letter we demonstrate the operation of an analog small-signal amplifier based on single-layer MoS2, a semiconducting analogue of graphene. Our device consists of two transistors integrated on the same piece of single-layer MoS2. The high intrinsic band gap of 1.8 eV allows MoS2-based amplifiers to operate with a room temperature gain of 4. The amplifier operation is demonstrated for the frequencies of input signal up to 2 kHz preserving the gain higher than 1. Our work shows that MoS2 can effectively amplify signals and that it could be used for advanced analog circuits based on two-dimensional materials.

  2. Implementation of a digital evaluation platform to analyze bifurcation based nonlinear amplifiers

    NASA Astrophysics Data System (ADS)

    Feldkord, Sven; Reit, Marco; Mathis, Wolfgang

    2016-09-01

    Recently, nonlinear amplifiers based on the supercritical Andronov-Hopf bifurcation have become a focus of attention, especially in the modeling of the mammalian hearing organ. In general, to gain deeper insights in the input-output behavior, the analysis of bifurcation based amplifiers requires a flexible framework to exchange equations and adjust certain parameters. A DSP implementation is presented which is capable to analyze various amplifier systems. Amplifiers based on the Andronov-Hopf and Neimark-Sacker bifurcations are implemented and compared exemplarily. It is shown that the Neimark-Sacker system remarkably outperforms the Andronov-Hopf amplifier regarding the CPU usage. Nevertheless, both show a similar input-output behavior over a wide parameter range. Combined with an USB-based control interface connected to a PC, the digital framework provides a powerful instrument to analyze bifurcation based amplifiers.

  3. Qualitative investigation of booster recovery in open sea

    NASA Technical Reports Server (NTRS)

    Beck, P. E.

    1973-01-01

    Limited tests were conducted using 1/27 scale model of a Titan 3C booster plus 1/32.9 and 1/15.6 scale models of a solid rocket booster case to establish some of the characteristics that will effect recovery operations in open seas. This preliminary effort was designed to provide additional background information for conceptual development of a waterborne recovery system for space shuttle boosters, pending initiation of comprehensive studies. The models were not instrumented; therefore, all data are qualitative (approximations) and are based on observations plus photographic coverage.

  4. Carpooling and booster seats: a national survey of parents.

    PubMed

    Macy, Michelle L; Clark, Sarah J; Freed, Gary L; Butchart, Amy T; Singer, Dianne C; Sasson, Comilla; Meurer, William J; Davis, Matthew M

    2012-02-01

    Booster seat use among school-aged children has been consistently lower than national goals. In this study, we sought to explore associations between parental experiences with booster seats and carpooling. We conducted a cross-sectional Web-based survey of a nationally representative panel of US parents in January 2010. As part of a larger survey, parents of 4- to 8-year-old children responded to 12 questions related to booster seats and carpooling. Of 1612 parents responding to the full survey (response rate = 71%), 706 had a 4- to 8-year-old child and 681 met inclusion rules. Most parents (76%) reported their child used a safety seat when riding in the family car. Of children reported to use seat belts, 74% did so in accordance with their state law. Parent report of child safety seat use was associated with younger child age and with the presence of state booster seat laws. Sixty-four percent of parents carpool. Among parents who carpool and whose children use a child safety seat: 79% indicated they would always ask another driver to use a booster seat for their child and 55% reported they always have their child use their booster seat when driving friends who do not have boosters. Carpooling is a common driving situation during which booster seat use is inconsistent. Social norms and self-efficacy are associated with booster seat use. Clinicians who care for children should increase efforts to convey the importance of using the size-appropriate restraint for every child on every trip.

  5. Compatibility of booster seats and vehicles in the U.S. market.

    PubMed

    Bing, Julie A; Agnew, Amanda M; Bolte, John H

    2018-05-19

    The objective of this study was to analyze booster and rear vehicle seat dimensions to identify the most frequent compatibility problems. Measurements were collected from 40 high-back and backless boosters and 95 left rear and center rear row seating positions in 50 modern vehicles. Dimensions were compared for 3,800 booster/vehicle seat combinations. For validation and estimation of tolerance and correction factors, 72 booster installations were physically completed and compared with measurement-based compatibility predictions. Dimensions were also compared to the International Organization for Standardization (ISO) volumetric envelopes of forward-facing child restraints and boosters. Seat belt buckles in outboard positions accommodated the width of boosters better than center positions (success rates of 85.4 and 34.7%, respectively). Adequate head restraint clearance occurred in 71.9 to 77.2% of combinations, depending on the booster's head support setting. Booster recline angles aligned properly with vehicle seat cushion angles in 71.5% of combinations. In cases of poor angle alignment, booster angles were more obtuse than the vehicle seat angles 97.7% of the time. Head restraint interference exacerbated angle alignment issues. Data indicate success rates above 90% for boosters being fully supported by the length of the seat cushion and for adequate height clearance with the vehicle roofline. Comparison to ISO envelopes indicates that most boosters on the U.S. market are taller and angled more obtusely than ISO target envelopes. This study quantifies some of the common interferences between boosters and vehicles that may complicate booster usage. Data are useful for design and to prioritize specific problem areas.

  6. Effects of booster interventions on factory workers' use of hearing protection.

    PubMed

    Lusk, Sally L; Eakin, Brenda L; Kazanis, Anamaria S; McCullagh, Marjorie C

    2004-01-01

    The provision of reinforcements or boosters to interventions is seen as a logical approach to enhancing or maintaining desired behavior. Empirical studies, however, have not confirmed the effectiveness of boosters nor assessed the optimum number of boosters or the timing for their delivery. This randomized controlled trial contrasted the effect of four booster conditions (a). 30 days; (b). 90 days; (c). 30 and at 90 days; and (d). no boosters of the intervention to increase the use of hearing protection devices (HPDs). A total of 1325 factory workers completed a computerized questionnaire and were randomly assigned to one of three computer-based (tailored, nontailored predictor-based, or control) multimedia interventions designed to increase the use of hearing protection devices. After the intervention, colorful boosters specific to the type of training received were mailed to workers' homes. Posttest measures of use were administered at the time of their next annual audiogram 6 to 18 months after the intervention. RESULTS Repeated measures of analysis of variance (ANOVA) showed a significant main effect for the booster (after 30 days) in the group that received tailored training (F[3442] = 2.722; p =.04). However, in the assessment of the interaction between time (pretest and posttest) and boosters (four groups), the ANOVA did not find significant differences in hearing protection device use for any of the training groups. To assess for significant differences between groups, post hoc comparisons were conducted at the pretest and posttest for the total sample and for the subsample of workers who reported using hearing protection devices less than 100% of the time needed. Sheffé contrasts by intervention group, gender, ethnicity, and hearing ability found no significant changes in the mean use of hearing protection devices for the booster groups. Although the provision of boosters represented a considerable commitment of resources, their use was not effective in

  7. Impact of Booster Breaks and Computer Prompts on Physical Activity and Sedentary Behavior Among Desk-Based Workers: A Cluster-Randomized Controlled Trial.

    PubMed

    Taylor, Wendell C; Paxton, Raheem J; Shegog, Ross; Coan, Sharon P; Dubin, Allison; Page, Timothy F; Rempel, David M

    2016-11-17

    The 15-minute work break provides an opportunity to promote health, yet few studies have examined this part of the workday. We studied physical activity and sedentary behavior among office workers and compared the results of the Booster Break program with those of a second intervention and a control group to determine whether the Booster Break program improved physical and behavioral health outcomes. We conducted a 3-arm, cluster-randomized controlled trial at 4 worksites in Texas from 2010 through 2013 to compare a group-based, structured Booster Break program to an individual-based computer-prompt intervention and a usual-break control group; we analyzed physiologic, behavioral, and employee measures such as work social support, quality of life, and perceived stress. We also identified consistent and inconsistent attendees of the Booster Break sessions. We obtained data from 175 participants (mean age, 43 y; 67% racial/ethnic minority). Compared with the other groups, the consistent Booster Break attendees had greater weekly pedometer counts (P < .001), significant decreases in sedentary behavior and self-reported leisure-time physical activity (P < .001), and a significant increase in triglyceride concentrations (P = .02) (levels remained within the normal range). Usual-break participants significantly increased their body mass index, whereas Booster Break participants maintained body mass index status during the 6 months. Overall, Booster Break participants were 6.8 and 4.3 times more likely to have decreases in BMI and weekend sedentary time, respectively, than usual-break participants. Findings varied among the 3 study groups; however, results indicate the potential for consistent attendees of the Booster Break intervention to achieve significant, positive changes related to physical activity, sedentary behavior, and body mass index.

  8. Frequency-Offset Cartesian Feedback Based on Polyphase Difference Amplifiers

    PubMed Central

    Zanchi, Marta G.; Pauly, John M.; Scott, Greig C.

    2010-01-01

    A modified Cartesian feedback method called “frequency-offset Cartesian feedback” and based on polyphase difference amplifiers is described that significantly reduces the problems associated with quadrature errors and DC-offsets in classic Cartesian feedback power amplifier control systems. In this method, the reference input and feedback signals are down-converted and compared at a low intermediate frequency (IF) instead of at DC. The polyphase difference amplifiers create a complex control bandwidth centered at this low IF, which is typically offset from DC by 200–1500 kHz. Consequently, the loop gain peak does not overlap DC where voltage offsets, drift, and local oscillator leakage create errors. Moreover, quadrature mismatch errors are significantly attenuated in the control bandwidth. Since the polyphase amplifiers selectively amplify the complex signals characterized by a +90° phase relationship representing positive frequency signals, the control system operates somewhat like single sideband (SSB) modulation. However, the approach still allows the same modulation bandwidth control as classic Cartesian feedback. In this paper, the behavior of the polyphase difference amplifier is described through both the results of simulations, based on a theoretical analysis of their architecture, and experiments. We then describe our first printed circuit board prototype of a frequency-offset Cartesian feedback transmitter and its performance in open and closed loop configuration. This approach should be especially useful in magnetic resonance imaging transmit array systems. PMID:20814450

  9. Orbital Payload Reductions Resulting from Booster and Trajectory Modifications for Recovery of a Large Rocket Booster

    NASA Technical Reports Server (NTRS)

    Levin, Alan D.; Hopkins, Edward J.

    1961-01-01

    An analysis was made to determine the reduction in payload for a 300 nautical mile orbit resulting from the addition of inert weight, representing recovery gear, to the first-stage booster of a three-stage rocket vehicle. The values of added inert weight investigated ranged from 0 to 18 percent of gross weight at lift off. The study also included the effects on the payload in orbit and the distance from the launch site at burnout and at impact caused by variation in the vertical rise time before the programmed tilt. The vertical rise times investigated ranged from 16-7 to 100 percent of booster burning time. For a vertical rise of 16.7 percent of booster burning time it was found that a 50-percent increase in the weight of the empty booster resulted in only a 10-percent reduction of the payload in orbit. For no added booster weight, increasing vertical rise time from 16-7 to 100 percent of booster burning time (so that the spent booster would impact in the launch area) reduced the payload by 37 percent. Increasing the vertical rise time from 16-7 to 50 percent of booster burning time resulted in about a 15-percent reduction in the impact distance, and for vertical rise times greater than 50-percent the impact distance decreased rapidly.

  10. Magnetic Amplifier-Based Power-Flow Controller

    DOE PAGES

    Dimitrovski, Aleksandar; Li, Zhi; Ozpineci, Burak

    2015-02-05

    The concept of the magnetic amplifier, a common electromagnetic device in electronic applications in the past, has seldom been used in power systems. In this paper, we introduce the magnetic amplifier-based power-flow controller (MAPFC), an innovative low-cost device that adopts the idea of the magnetic amplifier for power-flow control applications. The uniqueness of MAPFC is in the use of the magnetization of the ferromagnetic core, shared by an ac and a dc winding, as the medium to control the ac winding reactance inserted in series with the transmission line to be controlled. Large power flow in the line can bemore » regulated by the small dc input to the dc winding. Moreover, a project on the R&D of an MAPFC has been funded by the U.S. Department of Energy (DOE) and conducted by the Oak Ridge National Laboratory (ORNL), the University of Tennessee-Knoxville, and Waukesha Electric Systems, Inc. since early 2012. Findings from the project are presented along with some results obtained in a laboratory environment.« less

  11. Credit BG. Northwest facade of Building 4504 (Deluge Water Booster ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. Northwest facade of Building 4504 (Deluge Water Booster Station) is in view at left, with 500,000 gallon water tank (Building 4503) at right. Fenced electrical substation in view between the above structures is Building 4510. Building 4505 is in background - Edwards Air Force Base, North Base, Deluge Water Booster Station, Northeast of A Street, Boron, Kern County, CA

  12. Impact of Booster Breaks and Computer Prompts on Physical Activity and Sedentary Behavior Among Desk-Based Workers: A Cluster-Randomized Controlled Trial

    PubMed Central

    Paxton, Raheem J.; Shegog, Ross; Coan, Sharon P.; Dubin, Allison; Page, Timothy F.; Rempel, David M.

    2016-01-01

    Introduction The 15-minute work break provides an opportunity to promote health, yet few studies have examined this part of the workday. We studied physical activity and sedentary behavior among office workers and compared the results of the Booster Break program with those of a second intervention and a control group to determine whether the Booster Break program improved physical and behavioral health outcomes. Methods We conducted a 3-arm, cluster-randomized controlled trial at 4 worksites in Texas from 2010 through 2013 to compare a group-based, structured Booster Break program to an individual-based computer-prompt intervention and a usual-break control group; we analyzed physiologic, behavioral, and employee measures such as work social support, quality of life, and perceived stress. We also identified consistent and inconsistent attendees of the Booster Break sessions. Results We obtained data from 175 participants (mean age, 43 y; 67% racial/ethnic minority). Compared with the other groups, the consistent Booster Break attendees had greater weekly pedometer counts (P < .001), significant decreases in sedentary behavior and self-reported leisure-time physical activity (P < .001), and a significant increase in triglyceride concentrations (P = .02) (levels remained within the normal range). Usual-break participants significantly increased their body mass index, whereas Booster Break participants maintained body mass index status during the 6 months. Overall, Booster Break participants were 6.8 and 4.3 times more likely to have decreases in BMI and weekend sedentary time, respectively, than usual-break participants. Conclusion Findings varied among the 3 study groups; however, results indicate the potential for consistent attendees of the Booster Break intervention to achieve significant, positive changes related to physical activity, sedentary behavior, and body mass index. PMID:27854422

  13. Broadband parametric amplifiers based on nonlinear kinetic inductance artificial transmission lines

    NASA Astrophysics Data System (ADS)

    Chaudhuri, S.; Li, D.; Irwin, K. D.; Bockstiegel, C.; Hubmayr, J.; Ullom, J. N.; Vissers, M. R.; Gao, J.

    2017-04-01

    We present broadband parametric amplifiers based on the kinetic inductance of superconducting NbTiN thin films in an artificial (lumped-element) transmission line architecture. We demonstrate two amplifier designs implementing different phase matching techniques: periodic impedance loading and resonator phase shifters placed periodically along the transmission line. Our design offers several advantages over previous CPW-based amplifiers, including intrinsic 50 Ω characteristic impedance, natural suppression of higher pump harmonics, lower required pump power, and shorter total trace length. Experimental realizations of both versions of the amplifiers are demonstrated. With a transmission line length of 20 cm, we have achieved gains of 15 dB over several GHz of bandwidth.

  14. Solid Rocket Booster Separation

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This Quick Time movie shows the Space Shuttle Solid Rocket Booster (SRB) separation from the external tank (ET). After separation, the boosters fall to the ocean from which they are retrieved and refurbished for reuse. The Shuttle's SRB's and solid rocket motors (SRM's) are the largest ever built and the first designed for refurbishment and reuse. Standing nearly 150-feet high, the twin boosters provide the majority of thrust for the first two minutes of flight, about 5.8 million pounds. That is equivalent to 44 million horsepower, or the combined power of 400,000 subcompact cars.

  15. Developing the World's Most Powerful Solid Booster

    NASA Technical Reports Server (NTRS)

    Priskos, Alex S.; Frame, Kyle L.

    2016-01-01

    NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are underway with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant grain, asbestos-free case insulation, a redesigned nozzle, streamlined manufacturing

  16. 47 CFR 22.527 - Signal boosters.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal... additional transmitters for existing systems. Licensees must not allow any signal booster that they operate...

  17. 47 CFR 22.527 - Signal boosters.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal... additional transmitters for existing systems. Licensees must not allow any signal booster that they operate...

  18. Broadband parametric amplifiers based on nonlinear kinetic inductance artificial transmission lines

    DOE PAGES

    Chaudhuri, S.; Li, D.; Irwin, K. D.; ...

    2017-04-10

    Here, we present broadband parametric amplifiers based on the kinetic inductance of superconducting NbTiN thin films in an artificial (lumped-element) transmission line architecture. We demonstrate two amplifier designs implementing different phase matching techniques: periodic impedance loading and resonator phase shifters placed periodically along the transmission line. Our design offers several advantages over previous CPW-based amplifiers, including intrinsic 50 Ω characteristic impedance, natural suppression of higher pump harmonics, lower required pump power, and shorter total trace length. Experimental realizations of both versions of the amplifiers are demonstrated. In conclusion, with a transmission line length of 20 cm, we have achieved gainsmore » of 15 dB over several GHz of bandwidth.« less

  19. Broadband parametric amplifiers based on nonlinear kinetic inductance artificial transmission lines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chaudhuri, S.; Li, D.; Irwin, K. D.

    Here, we present broadband parametric amplifiers based on the kinetic inductance of superconducting NbTiN thin films in an artificial (lumped-element) transmission line architecture. We demonstrate two amplifier designs implementing different phase matching techniques: periodic impedance loading and resonator phase shifters placed periodically along the transmission line. Our design offers several advantages over previous CPW-based amplifiers, including intrinsic 50 Ω characteristic impedance, natural suppression of higher pump harmonics, lower required pump power, and shorter total trace length. Experimental realizations of both versions of the amplifiers are demonstrated. In conclusion, with a transmission line length of 20 cm, we have achieved gainsmore » of 15 dB over several GHz of bandwidth.« less

  20. Five-Segment Reusable Solid Rocket Booster Upgrade

    NASA Technical Reports Server (NTRS)

    Sauvageau, Don

    1999-01-01

    The Five Segment Reusable Solid Rocket Booster (RSRB) feasibility status is presented in viewgraph form. The Five Segment Booster (FSB) objective is to provide a low cost, low risk approach to increase reliability and safety of the Shuttle system. Topics include: booster upgrade requirements; design summary; reliability issues; booster trajectories; launch site assessment; and enhanced abort modes.

  1. Pressure-Equalizing Cradle for Booster Rocket Mounting

    NASA Technical Reports Server (NTRS)

    Rutan, Elbert L. (Inventor)

    2015-01-01

    A launch system and method improve the launch efficiency of a booster rocket and payload. A launch aircraft atop which the booster rocket is mounted in a cradle, is flown or towed to an elevation at which the booster rocket is released. The cradle provides for reduced structural requirements for the booster rocket by including a compressible layer, that may be provided by a plurality of gas or liquid-filled flexible chambers. The compressible layer contacts the booster rocket along most of the length of the booster rocket to distribute applied pressure, nearly eliminating bending loads. Distributing the pressure eliminates point loading conditions and bending moments that would otherwise be generated in the booster rocket structure during carrying. The chambers may be balloons distributed in rows and columns within the cradle or cylindrical chambers extending along a length of the cradle. The cradle may include a manifold communicating gas between chambers.

  2. Booster Interface Loads

    NASA Technical Reports Server (NTRS)

    Gentz, Steve; Wood, Bill; Nettles, Mindy

    2015-01-01

    The interaction between shock waves and the wake shed from the forward booster/core attach hardware results in unsteady pressure fluctuations, which can lead to large buffeting loads on the vehicle. This task investigates whether computational tools can adequately predict these flows, and whether alternative booster nose shapes can reduce these loads. Results from wind tunnel tests will be used to validate the computations and provide design information for future Space Launch System (SLS) configurations. The current work combines numerical simulations with wind tunnel testing to predict buffeting loads caused by the boosters. Variations in nosecone shape, similar to the Ariane 5 design (fig. 1), are being evaluated with regard to lowering the buffet loads. The task will provide design information for the mitigation of buffet loads for SLS, along with validated simulation tools to be used to assess future SLS designs.

  3. 47 CFR 22.527 - Signal boosters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal boosters on channels listed in § 22.531 only in accordance with the provisions of § 22.165 governing...

  4. 47 CFR 22.527 - Signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal boosters on channels listed in § 22.531 only in accordance with the provisions of § 22.165 governing...

  5. 47 CFR 22.527 - Signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal boosters on channels listed in § 22.531 only in accordance with the provisions of § 22.165 governing...

  6. Athena: Advanced air launched space booster

    NASA Astrophysics Data System (ADS)

    Booker, Corey G.; Ziemer, John; Plonka, John; Henderson, Scott; Copioli, Paul; Reese, Charles; Ullman, Christopher; Frank, Jeremy; Breslauer, Alan; Patonis, Hristos

    1994-06-01

    The infrastructure for routine, reliable, and inexpensive access of space is a goal that has been actively pursued over the past 50 years, but has yet not been realized. Current launch systems utilize ground launching facilities which require the booster vehicle to plow up through the dense lower atmosphere before reaching space. An air launched system on the other hand has the advantage of being launched from a carrier aircraft above this dense portion of the atmosphere and hence can be smaller and lighter compared to its ground based counterpart. The goal of last year's Aerospace Engineering Course 483 (AE 483) was to design a 227,272 kg (500,000 lb.) air launched space booster which would beat the customer's launch cost on existing launch vehicles by at least 50 percent. While the cost analysis conducted by the class showed that this goal could be met, the cost and size of the carrier aircraft make it appear dubious that any private company would be willing to invest in such a project. To avoid this potential pitfall, this year's AE 483 class was to design as large an air launched space booster as possible which can be launched from an existing or modification to an existing aircraft. An initial estimate of the weight of the booster is 136,363 kg (300,000 lb.) to 159,091 kg (350,000 lb.).

  7. Athena: Advanced air launched space booster

    NASA Technical Reports Server (NTRS)

    Booker, Corey G.; Ziemer, John; Plonka, John; Henderson, Scott; Copioli, Paul; Reese, Charles; Ullman, Christopher; Frank, Jeremy; Breslauer, Alan; Patonis, Hristos

    1994-01-01

    The infrastructure for routine, reliable, and inexpensive access of space is a goal that has been actively pursued over the past 50 years, but has yet not been realized. Current launch systems utilize ground launching facilities which require the booster vehicle to plow up through the dense lower atmosphere before reaching space. An air launched system on the other hand has the advantage of being launched from a carrier aircraft above this dense portion of the atmosphere and hence can be smaller and lighter compared to its ground based counterpart. The goal of last year's Aerospace Engineering Course 483 (AE 483) was to design a 227,272 kg (500,000 lb.) air launched space booster which would beat the customer's launch cost on existing launch vehicles by at least 50 percent. While the cost analysis conducted by the class showed that this goal could be met, the cost and size of the carrier aircraft make it appear dubious that any private company would be willing to invest in such a project. To avoid this potential pitfall, this year's AE 483 class was to design as large an air launched space booster as possible which can be launched from an existing or modification to an existing aircraft. An initial estimate of the weight of the booster is 136,363 kg (300,000 lb.) to 159,091 kg (350,000 lb.).

  8. Space shuttle: Aerodynamic characteristics of a composite booster/040A orbiter launch configuration with fin and booster body configuration effect contribution

    NASA Technical Reports Server (NTRS)

    Ainsworth, R. W.; Johnson, J. C.; Watts, L. L.

    1972-01-01

    An investigation was made of the fin configuration and booster body configuration effects on a composite booster/040A orbiter launch configuration. Aerodynamic performance and stability characteristics in pitch and yaw were obtained. Configurations tested included two stepped cylindrical bodies of different lengths with a conical nose, four fin shapes of various sizes and aspect ratios mounted in different positions around the base of the bodies, two base flare angles and three 040A orbiter configurations. The orbiter variations included a tailless configuration and two tail sizes. A tailless booster launch configuration with deflected petals (expanded flare sectors) was also tested. The model scale was 0.003366. Data were converted to coefficient form in near real time, punched on cards, and tabulated. The cards used in conjunction with a Benson-Lehner plotter were used to provide plotted data. At the end of the test, tabulated input forms were completed for the SADSAC computer program to aid in publishing the final test data report.

  9. NASA's Space Launch System Advanced Booster Development

    NASA Technical Reports Server (NTRS)

    Robinson, Kimberly F.; Crumbly, Christopher M.; May, Todd A.

    2014-01-01

    The National Aeronautics and Space Administration's (NASA's) Space Launch System (SLS) Program, managed at the Marshall Space Flight Center, is making progress toward delivering a new capability for human space flight and scientific missions beyond Earth orbit. NASA is executing this development within flat budgetary guidelines by using existing engines assets and heritage technology to ready an initial 70 metric ton (t) lift capability for launch in 2017, and then employing a block upgrade approach to evolve a 130-t capability after 2021. A key component of the SLS acquisition plan is a three-phased approach for the first-stage boosters. The first phase is to expedite the 70-t configuration by completing development of the Space Shuttle heritage 5-segment solid rocket boosters (SRBs) for the initial flights of SLS. Since no existing boosters can meet the performance requirements for the 130-t class SLS, the next phases of the strategy focus on the eventual development of advanced boosters with an expected thrust class potentially double the current 5-segment solid rocket booster capability of 3.88 million pounds of thrust each. The second phase in the booster acquisition plan is the Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) effort, for which contracts were awarded beginning in 2012 after a full and open competition, with a stated intent to reduce risks leading to an affordable advanced booster. NASA has awarded ABEDRR contracts to four industry teams, which are looking into new options for liquid-fuel booster engines, solid-fuel-motor propellants, and composite booster structures. Demonstrations and/or risk reduction efforts were required to be related to a proposed booster concept directly applicable to fielding an advanced booster. This paper will discuss the status of this acquisition strategy and its results toward readying both the 70 t and 130 t configurations of SLS. The third and final phase will be a full and open

  10. Thermal Analysis in Support of the Booster Separation Motor Crack Investigation

    NASA Technical Reports Server (NTRS)

    Davis, Darrell; Prickett, Terry; Turner, Larry D. (Technical Monitor)

    2001-01-01

    During a post-test inspection of a Booster Separation Motor (BSM) from a Lot Acceptance Test (LAT), a crack was noticed in the graphite throat. Since this was an out-of-family occurrence, an investigation team was formed to determine the cause of the crack. This paper will describe thermal analysis techniques used in support of this investigation. Models were generated to predict gradients in nominal motor conditions, as well as potentially anomalous conditions. Analysis was also performed on throats that were tested in the Laser Hardened Material Evaluation Laboratory (LHMEL). Some of these throats were pre-cracked, while others represented configurations designed to amplify effects of thermal stresses. Results from these analyses will be presented in this paper.

  11. Thermal Analysis in Support of the Booster Separation Motor Crack Investigation

    NASA Technical Reports Server (NTRS)

    Davis, Darrell; Prickett, Terry

    2002-01-01

    During a post-test inspection of a Booster Separation Motor (BSM) from a Lot Acceptance Test (LAT), a crack was noticed in the graphite throat. Since this was an out-of-family occurrence, an investigation team was formed to determine the cause of the crack. This paper will describe thermal analysis techniques used in support of this investigation. Models were generated to predict gradients in nominal motor conditions, as well as potentially anomalous conditions. Analysis was also performed on throats that were tested in the Laser Hardened Material Evaluation Laboratory (LHMEL). Some of these throats were pre-cracked, while others represented configurations designed to amplify effects of thermal stresses. Results from these analyses will be presented in this paper.

  12. Next generation solid boosters

    NASA Technical Reports Server (NTRS)

    Lund, R. K.

    1991-01-01

    Space transportation solid rocket motor systems; Shuttle derived heavy lift launch vehicles; advanced launch system (ALS) derived heavy lift launch vehicles; large launch solid booster vehicles are outlined. Performance capabilities and concept objectives are presented. Small launch vehicle concepts; enabling technologies; reusable flyback booster system; and high-performance solid motors for space are briefly described. This presentation is represented by viewgraphs.

  13. 47 CFR 74.733 - UHF translator signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

  14. 47 CFR 74.733 - UHF translator signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

  15. 47 CFR 74.733 - UHF translator signal boosters.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

  16. Design of the transfer line from booster to storage ring at 3 GeV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayar, C., E-mail: cafer.bayar@cern.ch; Ciftci, A. K., E-mail: abbas.kenan.ciftci@cern.ch

    The Synchrotron Booster Ring accelerates the e-beam up to 3 GeV and particles are transported from booster to storage ring by transfer line. In this study, two options are considered, the first one is a long booster which shares the same tunnel with storage ring and the second one is a compact booster. As a result, two transfer line are designed based on booster options. The optical design is constrained by the e-beam Twiss parameters entering and leaving the transfer line. Twiss parameters in the extraction point of booster are used for the entrance of transfer line and are matchedmore » in the exit of transfer line to the injection point of the storage ring.« less

  17. Space Launch System Booster Separation Aerodynamic Database Development and Uncertainty Quantification

    NASA Technical Reports Server (NTRS)

    Chan, David T.; Pinier, Jeremy T.; Wilcox, Floyd J., Jr.; Dalle, Derek J.; Rogers, Stuart E.; Gomez, Reynaldo J.

    2016-01-01

    The development of the aerodynamic database for the Space Launch System (SLS) booster separation environment has presented many challenges because of the complex physics of the ow around three independent bodies due to proximity e ects and jet inter- actions from the booster separation motors and the core stage engines. This aerodynamic environment is dicult to simulate in a wind tunnel experiment and also dicult to simu- late with computational uid dynamics. The database is further complicated by the high dimensionality of the independent variable space, which includes the orientation of the core stage, the relative positions and orientations of the solid rocket boosters, and the thrust lev- els of the various engines. Moreover, the clearance between the core stage and the boosters during the separation event is sensitive to the aerodynamic uncertainties of the database. This paper will present the development process for Version 3 of the SLS booster separa- tion aerodynamic database and the statistics-based uncertainty quanti cation process for the database.

  18. 30 CFR 57.8518 - Main and booster fans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

  19. 30 CFR 57.8518 - Main and booster fans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

  20. 30 CFR 57.8518 - Main and booster fans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

  1. 30 CFR 57.8518 - Main and booster fans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

  2. 30 CFR 57.8518 - Main and booster fans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

  3. StarBooster Demonstrator Cluster Configuration Analysis/Verification Program

    NASA Technical Reports Server (NTRS)

    DeTurris, Dianne J.

    2003-01-01

    In order to study the flight dynamics of the cluster configuration of two first stage boosters and upper-stage, flight-testing of subsonic sub-scale models has been undertaken using two glideback boosters launched on a center upper-stage. Three high power rockets clustered together were built and flown to demonstrate vertical launch, separation and horizontal recovery of the boosters. Although the boosters fly to conventional aircraft landing, the centerstage comes down separately under its own parachute. The goal of the project has been to collect data during separation and flight for comparison with a six degree of freedom simulation. The configuration for the delta wing canard boosters comes from a design by Starcraft Boosters, Inc. The subscale rockets were constructed of foam covered in carbon or fiberglass and were launched with commercially available solid rocket motors. The first set of boosters built were 3-ft tall with a 4-ft tall centerstage, and two additional sets of boosters were made that were each over 5-ft tall with a 7.5 ft centerstage. The rocket cluster is launched vertically, then after motor bum out the boosters are separated and flown to a horizontal landing under radio-control. An on-board data acquisition system recorded data during both the launch and glide phases of flight.

  4. Pain Assessment and Management After a Knowledge Translation Booster Intervention.

    PubMed

    Stevens, Bonnie J; Yamada, Janet; Promislow, Sara; Barwick, Melanie; Pinard, Marie

    2016-10-01

    Inadequate pain treatment leaves hospitalized children vulnerable to immediate and long-term sequelae. A multidimensional knowledge translation intervention (ie, the Evidence-based Practice for Improving Quality [EPIQ]) improved pain assessment, management, and intensity outcomes in 16 units at 8 Canadian pediatric hospitals. The sustained effectiveness of EPIQ over time is unknown, however. The goals of this study were to determine the following: (1) sustainability of the impact of EPIQ on pain assessment, management, and intensity outcomes 12, 24, and 36 months after EPIQ; (2) effectiveness of a pain practice change booster (Booster) intervention to sustain EPIQ outcomes over time; and (3) influence of context on sustainability. A prospective, repeated measures, cluster randomized controlled trial was undertaken in the 16 EPIQ units, 12 months after EPIQ completion, to determine the effectiveness of a practice change booster (Booster) to sustain EPIQ outcomes. Generalized estimating equation models examined outcomes controlling for child and unit contextual factors. Outcomes achieved during EPIQ were sustained in the use of any pain assessment measure (P = .01) and a validated pain assessment measure in the EPIQ units (P = .02) up to 36 months after EPIQ. Statistically significant improvements in pain management practices persisted in EPIQ units; results varied across time. There were no significant differences in outcomes after implementation of the Booster between the Booster and Nonbooster groups. Improved pain assessment and management practices were sustained after EPIQ; however, the Booster did not seem to provide additional impact. Copyright © 2016 by the American Academy of Pediatrics.

  5. Magnetic field errors tolerances of Nuclotron booster

    NASA Astrophysics Data System (ADS)

    Butenko, Andrey; Kazinova, Olha; Kostromin, Sergey; Mikhaylov, Vladimir; Tuzikov, Alexey; Khodzhibagiyan, Hamlet

    2018-04-01

    Generation of magnetic field in units of booster synchrotron for the NICA project is one of the most important conditions for getting the required parameters and qualitative accelerator operation. Research of linear and nonlinear dynamics of ion beam 197Au31+ in the booster have carried out with MADX program. Analytical estimation of magnetic field errors tolerance and numerical computation of dynamic aperture of booster DFO-magnetic lattice are presented. Closed orbit distortion with random errors of magnetic fields and errors in layout of booster units was evaluated.

  6. Solid rocket motors for the Space Shuttle booster.

    NASA Technical Reports Server (NTRS)

    Odom, J. B.

    1972-01-01

    The evolution of the space shuttle booster system is reviewed from its initial concepts based on liquid-propellant reusable boosters to the final selection of recoverable, solid-fuel rocket motors. The rationale associated with each of the several major decisions in the evolution process is discussed. It is shown that the external tank orbiter configuration emerging from the latest studies takes maximum advantage of the solid rocket motor development experience and promises to be the optimum configuration for fulfilling the paramount shuttle program requirements of minimum total development risk within acceptable costs.

  7. Design Optimization of Gas Generator Hybrid Propulsion Boosters

    NASA Technical Reports Server (NTRS)

    Weldon, Vincent; Phillips, Dwight; Fink, Larry

    1990-01-01

    A methodology used in support of a study for NASA/MSFC to optimize the design of gas generator hybrid propulsion booster for uprating the National Space Transportation System (NSTS) is presented. The objective was to compare alternative configurations for this booster approach, optimizing each candidate concept on different bases, in order to develop data for a trade table on which a final decision was based. The methodology is capable of processing a large number of independent and dependent variables, adjusting the overall subsystems characteristics to arrive at a best compromise integrated design to meet various specific optimization criteria subject to selected constraints. For each system considered, a detailed weight statement was generated along with preliminary cost and reliability estimates.

  8. 47 CFR 27.9 - Operation of certificated signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Operation of certificated signal boosters. 27.9... boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies... operate a signal booster. [78 FR 21564, Apr. 11, 2013] ...

  9. 47 CFR 27.9 - Operation of certificated signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false Operation of certificated signal boosters. 27.9... boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies... operate a signal booster. [78 FR 21564, Apr. 11, 2013] ...

  10. Shuttle Upgrade Using 5-Segment Booster (FSB)

    NASA Technical Reports Server (NTRS)

    Sauvageau, Donald R.; Huppi, Hal D.; McCool, A. A. (Technical Monitor)

    2000-01-01

    In support of NASA's continuing effort to improve the over-all safety and reliability of the Shuttle system- a 5-segment booster (FSB) has been identified as an approach to satisfy that overall objective. To assess the feasibility of a 5-segment booster approach, NASA issued a feasibility study contract to evaluate the potential of a 5-segment booster to improve the overall capability of the Shuttle system, especially evaluating the potential to increase the system reliability and safety. In order to effectively evaluate the feasibility of the 5-segment concept, a four-member contractor team was established under the direction of NASA Marshall Space Flight Center (MSFC). MSFC provided the overall program oversight and integration as well as program contractual management. The contractor team consisted of Thiokol, Boeing North American Huntington Beach (BNA), Lockheed Martin Michoud Space Systems (LMMSS) and United Space Alliance (USA) and their subcontractor bd Systems (Control Dynamics Division, Huntsville, AL). United Space Alliance included the former members of United Space Booster Incorporated (USBI) who managed the booster element portion of the current Shuttle solid rocket boosters. Thiokol was responsible for the overall integration and coordination of the contractor team across all of the booster elements. They were also responsible for all of the motor modification evaluations. Boeing North American (BNA) was responsible for all systems integration analyses, generation of loads and environments. and performance and abort mode capabilities. Lockheed Martin Michoud Space Systems (LMMSS) was responsible for evaluating the impacts of any changes to the booster on the external tank (ET), and evaluating any design changes on the external tank necessary to accommodate the FSB. USA. including the former USBI contingent. was responsible for evaluating any modifications to facilities at the launch site as well as any booster component design modifications.

  11. Space Shuttle: Static pressure distribution on Chrysler Corporation Space Division SERV booster configuration

    NASA Technical Reports Server (NTRS)

    Price, E. A.; Hull, J. J.; Rawls, E. A.

    1971-01-01

    A dual purpose test was conducted in the propulsion wind tunnel (PWT) to evaluate the performance of an aerospike engine, in the presence of a booster, and obtain forebody and base pressure distributions on the booster in which it is installed. The test item was a 2.5 percent scaled replica of the SERV booster employing a 5 percent spike length aerospike engine installed in the base region of the model. Cold flow air was used to simulate engine jet operation. Two booster configurations were investigated, one on which reentry aerospike engine thermal protection doors were installed, and another where the doors were removed. The data presented are representative of the latter configuration for a Mach number range of 0 to 1.25 at angles of attack of 0 and 8 degrees and 0 degrees angle of sideslip.

  12. Modeling of Semiconductor Optical Amplifier Gain Characteristics for Amplification and Switching

    NASA Astrophysics Data System (ADS)

    Mahad, Farah Diana; Sahmah, Abu; Supa'at, M.; Idrus, Sevia Mahdaliza; Forsyth, David

    2011-05-01

    The Semiconductor Optical Amplifier (SOA) is presently commonly used as a booster or pre-amplifier in some communication networks. However, SOAs are also a strong candidate for utilization as multi-functional elements in future all-optical switching, regeneration and also wavelength conversion schemes. With this in mind, the purpose of this paper is to simulate the performance of the SOA for improved amplification and switching functions. The SOA is modeled and simulated using OptSim software. In order to verify the simulated results, a MATLAB mathematical model is also used to aid the design of the SOA. Using the model, the gain difference between simulated and mathematical results in the unsaturated region is <1dB. The mathematical analysis is in good agreement with the simulation result, with only a small offset due to inherent software limitations in matching the gain dynamics of the SOA.

  13. A microwave cryogenic low-noise amplifier based on sige heterostructures

    NASA Astrophysics Data System (ADS)

    Ivanov, B. I.; Grajcar, M.; Novikov, I. L.; Vostretsov, A. G.; Il'ichev, E.

    2016-04-01

    A low-noise cryogenic amplifier for the measurement of weak microwave signals at sub-Kelvin temperatures is constructed. The amplifier has five stages based on SiGe bipolar heterostructure transistors and has a gain factor of 35 dB in the frequency band from 100 MHz to 4 GHz at an operating temperature of 800 mK. The parameters of a superconducting quantum bit measured with this amplifier in the ultralow-power mode are presented as an application example. The amplitude-frequency response of the "supercon-ducting qubit-coplanar cavity" structure is demonstrated. The ground state of the qubit is characterized in the quasi-dispersive measurement mode.

  14. Liquid boosters for Shuttle?

    NASA Astrophysics Data System (ADS)

    Robertson, Donald F.

    1989-12-01

    The use of liquid rocket boosters (LRBs) for the Space Shuttle is proposed. The advantages LRBs provide are improved flight safety due to the use of four engines instead of two and less environmental pollution than solid rocket boosters because LRBs utilize clean-burning fuels. The LRBs also permit very high launch rates and increased safety in assembly and mating of the Shuttle. Concerns about LRBs such as costs, diameter, support capability, and water recovery are examined.

  15. Design optimization of gas generator hybrid propulsion boosters

    NASA Technical Reports Server (NTRS)

    Weldon, Vincent; Phillips, Dwight U.; Fink, Lawrence E.

    1990-01-01

    A methodology used in support of a contract study for NASA/MSFC to optimize the design of gas generator hybrid propulsion booster for uprating the National Space Transportation System (NSTS) is presented. The objective was to compare alternative configurations for this booster approach, optimizing each candidate concept on different bases, in order to develop data for a trade table on which a final decision was based. The methodology is capable of processing a large number of independent and dependent variables, adjusting the overall subsystems characteristics to arrive at a best compromise integrated design to meet various specified optimization criteria subject to selected constraints. For each system considered, a detailed weight statement was generated along with preliminary cost and reliability estimates.

  16. BOOSTER CHLORINATION FOR MANAGING DISINFECTANT RESIDUALS

    EPA Science Inventory

    Booster chlorination is an approach to residual maintenance in which chlorine is applied at strategic locations within the distribution system. Situations in which booster chlorination may be most effective for maintaining a residual are explained informally in the context of a ...

  17. Design of 3 GeV booster ring lattice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Etisken, O., E-mail: ozgur.etisken@cern.ch; Ciftci, A. K., E-mail: abbas.kenan.ciftci@cern.ch

    2016-03-25

    The aim of this study is to design of a 3 GeV booster ring for the 3 GeV storage ring. Electrons are needed to be accelerated to 3.0 GeV from 0.15 GeV energy. In this frame, we studied on two options for booster ring; a compact booster and the booster that shares the same tunnel with the storage ring. The lattice type has been chosen FODO for both options, lattice parameters are calculated, sextupole magnets are used to decrease dynamic aperture problem and dynamic aperture calculations are also made with considering of the necessary conditions. After designing and calculating ofmore » the parameters, these designs have been compared with each other. In addition to this comparison, these booster design parameters have been compared with some world centers design parameters and the reliability of the booster design is seen. Beam optics, OPA and Elegant simulation programs have been used in the study calculations.« less

  18. Fox-7 for Insensitive Boosters

    DTIC Science & Technology

    2010-08-01

    cavitation , and therefore nucleation, to occur at each frequency. As well as producing ultrasound at different frequencies, the method of delivery of...processing techniques using ultrasound , designed to optimise FOX-7 crystal size and morphology to improve booster formulations, and results from these...7 booster formulations. Also included are particle processing techniques using ultrasound , designed to optimise FOX-7 crystal size and morphology

  19. CEPC booster design study

    DOE PAGES

    Bian, Tianjian; Gao, Jie; Zhang, Chuang; ...

    2017-12-10

    In September 2012, Chinese scientists proposed a Circular Electron Positron Collider (CEPC) in China at 240 GeV center-of-mass energy for Higgs studies. The booster provides 120 GeV electron and positron beams to the CEPC collider for top-up injection at 0.1 Hz. The design of the full energy booster ring of the CEPC is a challenge. The ejected beam energy is 120 GeV and the injected beam energy is 6 GeV. Here in this paper we describe two alternative schemes, the wiggler bend scheme and the normal bend scheme. For the wiggler bend scheme, we propose to operate the booster ringmore » as a large wiggler at low energy and as a normal ring at high energy to avoid the problem of very low dipole magnet fields. Finally, for the normal bend scheme, we implement the orbit correction to correct the earth field.« less

  20. CEPC booster design study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bian, Tianjian; Gao, Jie; Zhang, Chuang

    In September 2012, Chinese scientists proposed a Circular Electron Positron Collider (CEPC) in China at 240 GeV center-of-mass energy for Higgs studies. The booster provides 120 GeV electron and positron beams to the CEPC collider for top-up injection at 0.1 Hz. The design of the full energy booster ring of the CEPC is a challenge. The ejected beam energy is 120 GeV and the injected beam energy is 6 GeV. Here in this paper we describe two alternative schemes, the wiggler bend scheme and the normal bend scheme. For the wiggler bend scheme, we propose to operate the booster ringmore » as a large wiggler at low energy and as a normal ring at high energy to avoid the problem of very low dipole magnet fields. Finally, for the normal bend scheme, we implement the orbit correction to correct the earth field.« less

  1. 47 CFR 101.151 - Use of signal boosters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2012-10-01 2012-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

  2. 47 CFR 101.151 - Use of signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2013-10-01 2013-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

  3. 47 CFR 101.151 - Use of signal boosters.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2010-10-01 2010-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

  4. 47 CFR 101.151 - Use of signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2014-10-01 2014-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

  5. 47 CFR 101.151 - Use of signal boosters.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2011-10-01 2011-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

  6. Rocket stage - Trans-orbit booster Fregat

    NASA Astrophysics Data System (ADS)

    Asyushkin, V. A.; Papkov, O. V.

    1993-10-01

    This paper discusses a proposal for increasing the payload-carrying capability of a launch vehicle by using the Fregat booster stage (as the fourth stage for the R-7A launcher and as the fifth stage for the Proton launch vehicle). Particular attention is given to the tasks which the Fregat booster stage is designed to fulfill, the systems which are part of the Fregat, and the launch vehicles which will use Fregat as the upper stage. The main performance parameters of the Fregat stage are presented, as well as diagrams illustrating the performance of the Fregat booster stage.

  7. Angle amplifier based on multiplexed volume holographic gratings

    NASA Astrophysics Data System (ADS)

    Cao, Liangcai; Zhao, Yifei; He, Qingsheng; Jin, Guofan

    2008-03-01

    Angle amplifier of laser beam scanner is a widely used device in optical systems. Volume holographic optical elements can be applied in the angle amplifier. Compared with the traditional angle amplifier, it has the advantages of high angle resolution, high diffraction efficiency, small size, and high angle magnification and flexible design. Bragg anglewavelength- compensating recording method is introduced. Because of the Bragg compensatory relation between angle and wavelength, this device could be recorded at another wavelength. The design of the angle amplifier recording at the wavelength of 514.2nm for the working wavelength of 632.8nm is described. An optical setup for recording the angle amplifier device is designed and discussed. Experimental results in the photorefractive crystal Fe:LiNbO 3 demonstrate the feasibility of the angle amplifier scheme.

  8. Discretization analysis of bifurcation based nonlinear amplifiers

    NASA Astrophysics Data System (ADS)

    Feldkord, Sven; Reit, Marco; Mathis, Wolfgang

    2017-09-01

    Recently, for modeling biological amplification processes, nonlinear amplifiers based on the supercritical Andronov-Hopf bifurcation have been widely analyzed analytically. For technical realizations, digital systems have become the most relevant systems in signal processing applications. The underlying continuous-time systems are transferred to the discrete-time domain using numerical integration methods. Within this contribution, effects on the qualitative behavior of the Andronov-Hopf bifurcation based systems concerning numerical integration methods are analyzed. It is shown exemplarily that explicit Runge-Kutta methods transform the truncated normalform equation of the Andronov-Hopf bifurcation into the normalform equation of the Neimark-Sacker bifurcation. Dependent on the order of the integration method, higher order terms are added during this transformation.A rescaled normalform equation of the Neimark-Sacker bifurcation is introduced that allows a parametric design of a discrete-time system which corresponds to the rescaled Andronov-Hopf system. This system approximates the characteristics of the rescaled Hopf-type amplifier for a large range of parameters. The natural frequency and the peak amplitude are preserved for every set of parameters. The Neimark-Sacker bifurcation based systems avoid large computational effort that would be caused by applying higher order integration methods to the continuous-time normalform equations.

  9. Summary of Booster Development and Qualification Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Francois, Elizabeth G.; Harry, Herbert H.; Hartline, Ernest L.

    2012-06-21

    This report outlines booster development work done at Los Alamos National Laboratory from 2007 to present. The booster is a critical link in the initiation train of explosive assemblies, from complex devices like nuclear weapons to conventional munitions. The booster bridges the gap from a small, relatively sensitive detonator to an insensitive, but massive, main charge. The movement throughout the explosives development community is to use more and more insensitive explosive components. With that, more energy is needed out of the booster. It has to initiate reliably, promptly, powerfully and safely. This report is divided into four sections. The firstmore » provides a summary of a collaborative effort between LANL, LLNL, and AWE to identify candidate materials and uniformly develop a testing plan for new boosters. Important parameters and the tests required to measure them were defined. The nature of the collaboration and the specific goals of the participating partners has changed over time, but the booster development plan stands on its own merit as a complete description of the test protocol necessary to compare and qualify booster materials, and is discussed in its entirety in this report. The second section describes a project, which began in 2009 with the Department of Defense to develop replacement booster formulations for PBXN-7. Replacement of PBXN-7 was necessary because it contained Triaminotrinitrobenzene (TATB), which was becoming unavailable to the DoD and because it contained Cyclotrimethylenetrinitramine (RDX), which was sensitive and toxic. A LANL-developed explosive, Diaminoazoxyfurazan (DAAF), was an important candidate. This project required any replacement formulation be a drop-in replacement in existing munitions. This project was timely, in that it made use of the collaborative booster development project, and had the additional constraint of matching shock sensitivity. Additionally it needed to be a safety improvement, and a performance

  10. Predictors of Booster Response to Hepatitis B Vaccine at 15 years of age: A Cross-Sectional School-Based Study.

    PubMed

    Chen, Yu-Sheng; Chu, Chia-Hsiang; Wang, Jen-Hung; Lin, Jun-Song; Chang, Yung-Chieh

    2016-08-01

    The current consensus does not support the use of booster dose because of its anamnestic response in almost all children 15 years after universal infant hepatitis B virus (HBV) vaccination. However, in our clinical setting, numerous concerned parents request a booster administration for their children. We aimed to provide the possible predictors of booster response in adolescents before this booster administration. This study comprised a series of cross-sectional serological surveys of HBV markers in 15-year-old individuals between 2008 and 2012. Data on serum hepatitis B surface antigen, hepatitis B surface antibody (anti-HBs), and liver-function biomarkers in a total of 887 senior high-school students were collected. There were two parts to this study: HBV seroepidemiology and booster-response analysis to identify the possible response predictors and decay factors after the HBV booster administration. The overall anti-HBs and hepatitis B surface antigen seropositivity rates were 34.7% and 0.7%, respectively, and the median anti-HBs titer was 3.3 mIU/mL. Six weeks after one dose of recombinant HBV vaccine, the overall booster-response rate in the double-seronegative recipients was 94% (471/501). Among the participants whose initial anti-HBs titers were undetectable or low, 72.4% (247/341) and 95.6% (153/160), respectively, reactivated their anti-HBs titers ≥ 100 mIU/mL about 6 weeks after the booster administration. The likelihood of postbooster anti-HBs titer reaching an adequate protective level increased with the prebooster titer. The female participants had stronger anamnestic responses compared to the male participants. We found that the female participants and prebooster anti-HBs titers above the detection limit of the immunoassay were good predictors of HBV booster response. Copyright © 2015. Published by Elsevier B.V.

  11. Expendable second stage reusable space shuttle booster. Volume 2: Technical summary. Book 3: Booster vehicle modifications and ground systems definition

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A definition of the expendable second stage and space shuttle booster separation system is presented. Modifications required on the reusable booster for expendable second stage/payload flight and the ground systems needed to operate the expendable second stage in conjuction with the space shuttle booster are described. The safety, reliability, and quality assurance program is explained. Launch complex operations and services are analyzed.

  12. Shuttle Boosters stacked in the VAB

    NASA Image and Video Library

    2007-01-04

    Workers continue stacking the solid rocket boosters in highbay 1 inside Kennedy Space Center's Vehicle Assembly Building. The solid rocket boosters are being prepared for NASA's next Space Shuttle launch, mission STS-117. The mission is scheduled to launch aboard Atlantis no earlier than March 16, 2007.

  13. Characterization of a measurement-based noiseless linear amplifier and its applications

    NASA Astrophysics Data System (ADS)

    Zhao, Jie; Haw, Jing Yan; Symul, Thomas; Lam, Ping Koy; Assad, Syed M.

    2017-07-01

    A noiseless linear amplifier (NLA) adds no noise to the signals it processes, which works only in a probabilistic way. It can be realized approximately with either a physical implementation that truncates the working space of the NLA on a photon-number basis or a measurement-based implementation that realizes the truncation virtually by a bounded postselection filter. To examine the relationship between these two approximate NLAs, we characterize in detail the measurement-based NLA and compare it with its physical counterpart in terms of their abilities to preserve the state Gaussianity and their probability of success. The link between these amplifiers is further clarified by integrating them into a measure-and-prepare setup. We stress the equivalence between the physical and the measurement-based approaches holds only when the effective parameters, the amplification gain, the cutoff, and the amplitude of the input state, are taken into account. Finally, we construct a 1-to-infinity cloner using the two amplifiers and show that a fidelity surpassing the no-cloning limit is achievable with the measurement-based NLA.

  14. Space Shuttle Five-Segment Booster (Short Course)

    NASA Technical Reports Server (NTRS)

    Graves, Stanley R.; Rudolphi, Michael (Technical Monitor)

    2002-01-01

    NASA is considering upgrading the Space Shuttle by adding a fifth segment (FSB) to the current four-segment solid rocket booster. Course materials cover design and engineering issues related to the Reusable Solid Rocket Motor (RSRM) raised by the addition of a fifth segment to the rocket booster. Topics cover include: four segment vs. five segment booster, abort modes, FSB grain design, erosive burning, enhanced propellant burn rate, FSB erosive burning model development and hardware configuration.

  15. Shuttle Boosters stacked in the VAB

    NASA Image and Video Library

    2007-01-04

    Workers continue stacking the twin solid rocket boosters in highbay 1 inside Kennedy Space Center's Vehicle Assembly Building. The solid rocket boosters are being prepared for NASA's next Space Shuttle launch, mission STS-117. The mission is scheduled to launch aboard Atlantis no earlier than March 16, 2007.

  16. Evaluation of give kids a boost: A school-based program to increase booster seat use among urban children in economically disadvantaged areas.

    PubMed

    Yellman, Merissa A; Rodriguez, Marissa A; Colunga, Maria Isabel; McCoy, Mary A; Stephens-Stidham, Shelli; Brown, L Steven; Istre, Gregory R

    2018-05-19

    This study evaluated the effectiveness of a series of 1-year multifaceted school-based programs aimed at increasing booster seat use among urban children 4-7 years of age in economically disadvantaged areas. During 4 consecutive school years, 2011-2015, the Give Kids a Boost (GKB) program was implemented in a total of 8 schools with similar demographics in Dallas County. Observational surveys were conducted at project schools before project implementation (P 0 ), 1-4 weeks after the completion of project implementation (P 1 ), and 4-5 months later (P 2 ). Changes in booster seat use for the 3 time periods were compared for the 8 project and 14 comparison schools that received no intervention using a nonrandomized trial process. The intervention included (1) train-the-trainer sessions with teachers and parents; (2) presentations about booster seat safety; (3) tailored communication to parents; (4) distribution of fact sheets/resources; (5) walk-around education; and (6) booster seat inspections. The association between the GKB intervention and proper booster seat use was determined initially using univariate analysis. The association was also estimated using a generalized linear mixed model predicting a binomial outcome (booster seat use) for those aged 4 to 7 years, adjusted for child-level variables (age, sex, race/ethnicity) and car-level variables (vehicle type). The model incorporated the effects of clustering by site and by collection date to account for the possibility of repeated sampling. In the 8 project schools, booster seat use for children 4-7 years of age increased an average of 20.9 percentage points between P 0 and P 1 (P 0 = 4.8%, P 1 = 25.7%; odds ratio [OR] = 6.9; 95% confidence interval [CI], 5.5, 8.7; P < .001) and remained at that level in the P 2 time period (P 2 = 25.7%; P < .001, for P 0 vs. P 2 ) in the univariate analysis. The 14 comparison schools had minimal change in booster seat use. The multivariable model showed that children at

  17. Evaluation of Safe Kids Week 2004: Age 4 to 9? It's Booster Seat Time!

    PubMed Central

    Howard, A; Beben, N; Rothman, L; Fiissel, D; MacArthur, C

    2006-01-01

    Objective To assess the effectiveness of a national one week media campaign promoting booster seat use. Design Pre‐test, post‐test design based on nationally representative random digit dialing telephone survey, with control for exposure to campaign. Setting Canada. Subjects Parents of children aged 4–9 years. Interventions During a one week campaign in May 2004, information on booster seat use was distributed via a national media campaign, retail stores, medical clinics, and community events. Information included pamphlets with guidelines for booster seat use, as well as a growth chart (designed by Safe Kids Canada) to assist parents in determining if their child should be using a booster seat. Assessing seat belt fit was described in detail on the growth chart. Main outcome measures Knowledge, attitudes, and self‐reported behaviors regarding booster seat use. Results Respondents in the group exposed to the campaign were twice as likely to report using a booster seat with lap and shoulder belt for their child (47%), compared to those in the pre‐test (24%) and the unexposed (23%) groups (p<0.001). However, only small differences in general knowledge regarding booster seat use were found between the groups. Conclusions A one week national media campaign substantially increased self‐reported use of booster seats. Parents did not remember details of the campaign content, but did remember implications for their own child. PMID:17018673

  18. Evaluation of Safe Kids Week 2004: age 4 to 9? It's booster seat time!

    PubMed

    Howard, A; Beben, N; Rothman, L; Fiissel, D; MacArthur, C

    2006-10-01

    To assess the effectiveness of a national one week media campaign promoting booster seat use. Pre-test, post-test design based on nationally representative random digit dialing telephone survey, with control for exposure to campaign. Canada. Parents of children aged 4-9 years. During a one week campaign in May 2004, information on booster seat use was distributed via a national media campaign, retail stores, medical clinics, and community events. Information included pamphlets with guidelines for booster seat use, as well as a growth chart (designed by Safe Kids Canada) to assist parents in determining if their child should be using a booster seat. Assessing seat belt fit was described in detail on the growth chart. Knowledge, attitudes, and self-reported behaviors regarding booster seat use. Respondents in the group exposed to the campaign were twice as likely to report using a booster seat with lap and shoulder belt for their child (47%), compared to those in the pre-test (24%) and the unexposed (23%) groups (p<0.001). However, only small differences in general knowledge regarding booster seat use were found between the groups. A one week national media campaign substantially increased self-reported use of booster seats. Parents did not remember details of the campaign content, but did remember implications for their own child.

  19. Digital lock-in amplifier based on soundcard interface for physics laboratory

    NASA Astrophysics Data System (ADS)

    Sinlapanuntakul, J.; Kijamnajsuk, P.; Jetjamnong, C.; Chotikaprakhan, S.

    2017-09-01

    The purpose of this paper is to develop a digital lock-in amplifier based on soundcard interface for undergraduate physics laboratory. Both series and parallel RLC circuit laboratory are tested because of its well-known, easy to understand and simple confirm. The sinusoidal signal at the frequency of 10 Hz - 15 kHz is generated to the circuits. The amplitude and phase of the voltage drop across the resistor, R are measured in 10 step decade. The signals from soundcard interface and lock-in amplifier are compared. The results give a good correlation. It indicates that the design digital lock-in amplifier is promising for undergraduate physic laboratory.

  20. 47 CFR 20.21 - Signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... operation to ensure compliance with applicable noise and gain limits and either self-correct or shut down... provide equivalent uplink and downlink gain and conducted uplink power output that is at least 0.05 watts... referenced to the booster's input port for each band of operation. (C) Booster Gain Limits. (1) The uplink...

  1. 47 CFR 20.21 - Signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... operation to ensure compliance with applicable noise and gain limits and either self-correct or shut down... provide equivalent uplink and downlink gain and conducted uplink power output that is at least 0.05 watts... referenced to the booster's input port for each band of operation. (C) Booster Gain Limits. (1) The uplink...

  2. 47 CFR 24.9 - Operation of certificated signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Operation of certificated signal boosters. 24.9... PERSONAL COMMUNICATIONS SERVICES General Information § 24.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated...

  3. 47 CFR 24.9 - Operation of certificated signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false Operation of certificated signal boosters. 24.9... PERSONAL COMMUNICATIONS SERVICES General Information § 24.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated...

  4. 47 CFR 22.9 - Operation of certificated signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Operation of certificated signal boosters. 22.9... PUBLIC MOBILE SERVICES Scope and Authority § 22.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated under...

  5. 47 CFR 22.9 - Operation of certificated signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false Operation of certificated signal boosters. 22.9... PUBLIC MOBILE SERVICES Scope and Authority § 22.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated under...

  6. Evaluation of a Booster Intervention Three Years after Acute Treatment for Early-Onset Disruptive Behavior Disorders

    PubMed Central

    Lindhiem, Oliver; Hart, Jonathan; Bukstein, Oscar G.

    2013-01-01

    This study examines the impact of a brief booster treatment administered three years after the delivery of an acute treatment in a group (N = 118) of clinically referred boys and girls (ages 6 to 11) originally diagnosed with Oppositional Defiant Disorder (ODD) or Conduct Disorder (CD). At the conclusion of the acute treatment and three-year follow-up period (i.e., study month 42), the sample was re-randomized into Booster treatment or Enhanced Usual Care and then assessed at four later timepoints (i.e., post-booster, and 6-, 12- and 24-month booster follow-up). Booster treatment was directed towards addressing individualized problems and some unique developmental issues of adolescence based on the same original protocol content and treatment setting, whereas the no-booster condition involved providing clinical recommendations based on the assessment and an outside referral for services. HLM analyses identified no significant group differences and few time effects across child, parent, and teacher reports on a broad range of child functioning and impairment outcomes. Analyses examining the role of putative moderators or mediators (e.g., severity of externalizing behavior, dose of treatment) were likewise non-significant. We discuss the nature and implications of these novel findings regarding the role and timing of booster treatment to address the continuity of DBD over time. PMID:23494526

  7. EELV Booster Assist Options for CEV

    NASA Technical Reports Server (NTRS)

    McNeal, Curtis, Jr.

    2005-01-01

    Medium lift EELVs may still play a role in manned space flight. To be considered for manned flight, medium lift EELVs must address the short comings in their current boost assist motors. Two options exist: redesign and requalify the solid rocket motors. Replace solid rocket motors (SRMs) with hybrid rocket motors. Hybrid rocket motors are an attractive alternative. They are safer than SRMs. The TRL's Lockheed Martin Small Launch Vehicle booster development substantially lowers the development risk, cost risk, and the schedule risk for developing hybrid boost assist for EELVs. Hybrid boosters testability offsets SRMs higher inherent reliability.Hybrid booster development and recurring costs are lower than SRMs. Performance gains are readily achieved.

  8. Room-temperature electron spin amplifier based on Ga(In)NAs alloys.

    PubMed

    Puttisong, Yuttapoom; Buyanova, Irina A; Ptak, Aaron J; Tu, Charles W; Geelhaar, Lutz; Riechert, Henning; Chen, Weimin M

    2013-02-06

    The first experimental demonstration of a spin amplifier at room temperature is presented. An efficient, defect-enabled spin amplifier based on a non-magnetic semiconductor, Ga(In)NAs, is proposed and demonstrated, with a large spin gain (up to 2700% at zero field) for conduction electrons and a high cut-off frequency of up to 1 GHz. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Analysis of delayed TBE-vaccine booster after primary vaccination.

    PubMed

    Aerssens, Annelies; Cochez, Christel; Niedrig, Matthias; Heyman, Paul; Kühlmann-Rabens, Ilona; Soentjens, Patrick

    2016-02-01

    An open, uncontrolled single centre study was conducted in the Travel Clinic at the Military Hospital, Brussels. Eighty-eight subjects were recruited who had a primary series of tick-borne encephalitis (TBE) vaccine more than 5 years ago and who never received a booster dose afterwards. Response rate after booster vaccination was very high: 84 out of 88 subjects (95.5%) had neutralizing antibodies on plaque reduction neutralization test and all (100%) had IgG antibodies on ELISA, on Day 21-28 after booster vaccination. This study adds valuable information to the common situation of delayed booster interval. The results of our study indicate that in young healthy travellers (<50 years), one booster vaccination after a primary series of TBE vaccine in the past is sufficient to obtain protective antibodies, even if primary vaccination is much longer than the recommended booster interval of 5 years. © International Society of Travel Medicine, 2016. All rights reserved.For permissions, please e-mail: journals.permissions@oup.com.

  10. Shuttle Boosters stacked in the VAB

    NASA Image and Video Library

    2007-01-04

    Lighting inside Kennedy Space Center's Vehicle Assembly Building seems to bathe the highbay 1 area in a golden hue as workers continue stacking the twin solid rocket boosters. The solid rocket boosters are being prepared for NASA's next Space Shuttle launch, mission STS-117. The mission is scheduled to launch aboard Atlantis no earlier than March 16, 2007.

  11. Booster Separation Motor (BSM) Test Fire

    NASA Technical Reports Server (NTRS)

    2007-01-01

    This photograph depicts a hot fire test of the Shuttle Booster Separation Motor (BSM) at the Marshall Space Flight Center (MSFC) test stand 116. The objective of the test was to test the aft heat seal in flight configuration. The function of the motor is to separate the Shuttle vehicle from the boosters that carry it into space.

  12. High power pulsed sources based on fiber amplifiers

    NASA Astrophysics Data System (ADS)

    Canat, Guillaume; Jaouën, Yves; Mollier, Jean-Claude; Bouzinac, Jean-Pierre; Cariou, Jean-Pierre

    2017-11-01

    Cladding-pumped rare-earth-doped fiber laser technologies are currently among the best sources for high power applications. Theses extremely compact and robust sources appoint them as good candidate for aeronautical and space applications. The double-clad (DC) fiber converts the poor beamquality of high-power large-area pump diodes from the 1st cladding to laser light at another wavelength guided in an active single-mode core. High-power coherent MOPA (Master Oscillator Power Amplifier) sources (several 10W CW or several 100W in pulsed regime) will soon be achieved. Unfortunately it also brings nonlinear effects which quickly impairs output signal distortions. Stimulated Brillouin scattering (SBS) and optical parametric amplification (OPA) have been shown to be strong limitations. Based on amplifier modeling and experiments we discuss the performances of these sources.

  13. Analysis of quasi-hybrid solid rocket booster concepts for advanced earth-to-orbit vehicles

    NASA Technical Reports Server (NTRS)

    Zurawski, Robert L.; Rapp, Douglas C.

    1987-01-01

    A study was conducted to assess the feasibility of quasi-hybrid solid rocket boosters for advanced Earth-to-orbit vehicles. Thermochemical calculations were conducted to determine the effect of liquid hydrogen addition, solids composition change plus liquid hydrogen addition, and the addition of an aluminum/liquid hydrogen slurry on the theoretical performance of a PBAN solid propellant rocket. The space shuttle solid rocket booster was used as a reference point. All three quasi-hybrid systems theoretically offer higher specific impulse when compared with the space shuttle solid rocket boosters. However, based on operational and safety considerations, the quasi-hybrid rocket is not a practical choice for near-term Earth-to-orbit booster applications. Safety and technology issues pertinent to quasi-hybrid rocket systems are discussed.

  14. Hepatitis B virus vaccination booster does not provide additional protection in adolescents: a cross-sectional school-based study.

    PubMed

    Chang, Yung-Chieh; Wang, Jen-Hung; Chen, Yu-Sheng; Lin, Jun-Song; Cheng, Ching-Feng; Chu, Chia-Hsiang

    2014-09-23

    Current consensus does not support the use of a universal booster of hepatitis B virus (HBV) vaccine because there is an anamnestic response in almost all children 15 years after universal infant HBV vaccination. We aimed to provide a booster strategy among adolescents as a result of their changes in lifestyle and sexual activity. This study comprised a series of cross-sectional serological surveys of HBV markers in four age groups between 2004 and 2012. The seropositivity rates of hepatitis B surface antigen (HBsAg) and its reciprocal antibody (anti-HBs) for each age group were collected. There were two parts to this study; age-specific HBV seroepidemiology and subgroup analysis, including effects of different vaccine types, booster response for immunogenicity at 15 years of age, and longitudinal follow-up to identify possible additional protection by HBV booster. Within the study period, data on serum anti-HBs and HBsAg in a total of 6950 students from four age groups were collected. The overall anti-HBs and HBsAg seropositivity rates were 44.3% and 1.2%, respectively. The anti-HBs seropositivity rate in the plasma-derived subgroup was significantly higher in both 15- and 18-year age groups. Overall response rate in the double-seronegative recipients at 15 years of age was 92.5% at 6 weeks following one recombinant HBV booster dose. Among the 24 recipients showing anti-HBs seroconversion at 6 weeks after booster, seven subjects (29.2%) had lost their anti-HBs seropositivity again within 3 years. Increased seropositivity rates and titers of anti-HBs did not provide additional protective effects among subjects comprehensively vaccinated against HBV in infancy. HBV booster strategy at 15 years of age was the main contributor to the unique age-related phenomenon of anti-HBs seropositivity rate and titer. No increase in HBsAg seropositivity rates within different age groups was observed. Vaccination with plasma-derived HBV vaccines in infancy provided higher

  15. SIMULATIONS OF TRANSVERSE STACKING IN THE NSLS-II BOOSTER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fliller III, R.; Shaftan, T.

    2011-03-28

    The NSLS-II injection system consists of a 200 MeV linac and a 3 GeV booster. The linac needs to deliver 15 nC in 80 - 150 bunches to the booster every minute to achieve current stability goals in the storage ring. This is a very stringent requirement that has not been demonstrated at an operating light source. We have developed a scheme to transversely stack two bunch trains in the NSLS-II booster in order to alleviate the charge requirements on the linac. This scheme has been outlined previously. In this paper we show particle tracking simulations of the tracking scheme.more » We show simulations of the booster ramp with a stacked beam for a variety of lattice errors and injected beam parameters. In all cases the performance of the proposed stacking method is sufficient to reduce the required charge from the linac. For this reason the injection system of the NSLS-II booster is being designed to include this feature. The NSLS-II injection system consists of a 200 MeV linac and a 3 GeV booster. The injectors must provide 7.5nC in bunch trains 80-150 bunches long every minute for top off operation of the storage ring. Top off then requires that the linac deliver 15nC of charge once losses in the injector chain are taken into consideration. This is a very stringent requirement that has not been demonstrated at an operating light source. For this reason we have developed a method to transversely stack two bunch trains in the booster while maintaining the charge transport efficiency. This stacking scheme has been discussed previously. In this paper we show the simulations of the booster ramp with a single bunch train in the booster. Then we give a brief overview of the stacking scheme. Following, we show the results of stacking two bunch trains in the booster with varying beam emittances and train separations. The behavior of the beam through the ramp is examined showing that it is possible to stack two bunch trains in the booster.« less

  16. 47 CFR 74.1233 - Processing FM translator and booster station applications.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

  17. 47 CFR 74.1233 - Processing FM translator and booster station applications.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

  18. 47 CFR 74.1233 - Processing FM translator and booster station applications.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

  19. 47 CFR 74.1233 - Processing FM translator and booster station applications.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

  20. 47 CFR 74.1233 - Processing FM translator and booster station applications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

  1. GRYPHON: Air launched space booster

    NASA Astrophysics Data System (ADS)

    1993-06-01

    The project chosen for the winter semester Aero 483 class was the design of a next generation Air Launched Space Booster. Based on Orbital Sciences Corporation's Pegasus concept, the goal of Aero 483 was to design a 500,000 pound air launched space booster capable of delivering 17,000 pounds of payload to Low Earth Orbit and 8,000 pounds of payload to Geosynchronous Earth Orbit. The resulting launch vehicle was named the Gryphon. The class of forty senior aerospace engineering students was broken down into eight interdependent groups. Each group was assigned a subsystem or responsibility which then became their field of specialization. Spacecraft Integration was responsible for ensuring compatibility between subsystems. This group kept up to date on subsystem redesigns and informed those parties affected by the changes, monitored the vehicle's overall weight and dimensions, and calculated the mass properties of the booster. This group also performed the cost/profitability analysis of the Gryphon and obtained cost data for competing launch systems. The Mission Analysis Group was assigned the task of determining proper orbits, calculating the vehicle's flight trajectory for those orbits, and determining the aerodynamic characteristics of the vehicle. The Propulsion Group chose the engines that were best suited to the mission. This group also set the staging configurations for those engines and designed the tanks and fuel feed system. The commercial satellite market, dimensions and weights of typical satellites, and method of deploying satellites was determined by the Payloads Group. In addition, Payloads identified possible resupply packages for Space Station Freedom and identified those packages that were compatible with the Gryphon. The guidance, navigation, and control subsystems were designed by the Mission Control Group. This group identified required tracking hardware, communications hardware telemetry systems, and ground sites for the location of the Gryphon

  2. GRYPHON: Air launched space booster

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The project chosen for the winter semester Aero 483 class was the design of a next generation Air Launched Space Booster. Based on Orbital Sciences Corporation's Pegasus concept, the goal of Aero 483 was to design a 500,000 pound air launched space booster capable of delivering 17,000 pounds of payload to Low Earth Orbit and 8,000 pounds of payload to Geosynchronous Earth Orbit. The resulting launch vehicle was named the Gryphon. The class of forty senior aerospace engineering students was broken down into eight interdependent groups. Each group was assigned a subsystem or responsibility which then became their field of specialization. Spacecraft Integration was responsible for ensuring compatibility between subsystems. This group kept up to date on subsystem redesigns and informed those parties affected by the changes, monitored the vehicle's overall weight and dimensions, and calculated the mass properties of the booster. This group also performed the cost/profitability analysis of the Gryphon and obtained cost data for competing launch systems. The Mission Analysis Group was assigned the task of determining proper orbits, calculating the vehicle's flight trajectory for those orbits, and determining the aerodynamic characteristics of the vehicle. The Propulsion Group chose the engines that were best suited to the mission. This group also set the staging configurations for those engines and designed the tanks and fuel feed system. The commercial satellite market, dimensions and weights of typical satellites, and method of deploying satellites was determined by the Payloads Group. In addition, Payloads identified possible resupply packages for Space Station Freedom and identified those packages that were compatible with the Gryphon. The guidance, navigation, and control subsystems were designed by the Mission Control Group. This group identified required tracking hardware, communications hardware telemetry systems, and ground sites for the location of the Gryphon

  3. Solid Rocket Boosters Separation

    NASA Technical Reports Server (NTRS)

    1982-01-01

    This view, taken by a motion picture tracking camera for the STS-3 mission, shows both left and right solid rocket boosters (SRB's) at the moment of separation from the external tank (ET). After impact to the ocean, they were retrieved and refurbished for reuse. The Shuttle's SRB's and solid rocket motors (SRM's) are the largest ever built and the first designed for refurbishment and reuse. Standing nearly 150-feet high, the twin boosters provide the majority of thrust for the first two minutes of flight, about 5.8 million pounds. That is equivalent to 44 million horsepower, or the combined power of 400,000 subcompact cars.

  4. DIRECT COUPLED AMPLIFIER

    DOEpatents

    Dandl, R.A.

    1961-09-19

    A transistor amplifier is designed for vyery small currents below 10/sup -8/ amperes. The filrst and second amplifier stages use unusual selected transistors in which the current amplification increases markedly for values of base current below 10/sup -6/ amperes.

  5. Perpendicular Biased Ferrite Tuned Cavities for the Fermilab Booster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Romanov, Gennady; Awida, Mohamed; Khabiboulline, Timergali

    2014-07-01

    The aging Fermilab Booster RF system needs an upgrade to support future experimental program. The important feature of the upgrade is substantial enhancement of the requirements for the accelerating cavities. The new requirements include enlargement of the cavity beam pipe aperture, increase of the cavity voltage and increase in the repetition rate. The modification of the present traditional parallel biased ferrite cavities is rather challenging. An alternative to rebuilding the present Fermilab Booster RF cavities is to design and construct new perpendicular biased RF cavities, which potentially offer a number of advantages. An evaluation and a preliminary design of themore » perpendicular biased ferrite tuned cavities for the Fermilab Booster upgrade is described in the paper. Also it is desirable for better Booster performance to improve the capture of beam in the Booster during injection and at the start of the ramp. One possible way to do that is to flatten the bucket by introducing second harmonic cavities into the Booster. This paper also looks into the option of using perpendicularly biased ferrite tuners for the second harmonic cavities.« less

  6. Effective amplifier noise for an optical receiver based on linear mode avalanche photodiodes

    NASA Technical Reports Server (NTRS)

    Chen, C.-C.

    1989-01-01

    The rms noise charge induced by the amplifier for an optical receiver based on the linear-mode avalanche photodiode (APD) was analyzed. It is shown that for an amplifier with a 1-pF capacitor and a noise temperature of 100 K, the rms noise charge due to the amplifier is about 300. Since the noise charge must be small compared to the signal gain, APD gains on the order of 1000 will be required to operate the receiver in the linear mode.

  7. The qualification of the shuttle booster separation motors

    NASA Technical Reports Server (NTRS)

    Chase, C. A.; Fisher, K. M.; Eoff, W.

    1978-01-01

    Four booster separation motors (BSM) located at each end of every solid rocket booster (SRB) provide the needed side force to separate the boosters from the external tank at booster burnout. Four BSMs at the top of the SRB are located in a box pattern in the nose cone frustum. The four BSMs at the aft end of the SRB are arranged side-by-side on the SRB aft skirt. Aspects of BSM design and performance are considered, taking into account a motor design/performance summary, the case design, the insulation, the grain design, the nozzle/aft closure design, the ignition system, the propellant, and the motor assembly. Details of motor testing are also discussed, giving attention to development testing, qualification testing, and flight testing.

  8. Closeup view of the Solid Rocket Booster Frustum and Nose ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster Frustum and Nose Cap assembly undergoing preparations and close-out procedures in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center. The Nose Cap contains the Pilot and Drogue Chutes and the Frustum contains the three Main Parachutes, Altitude Switches and forward booster Separation Motors. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  9. BERLinPro Booster Cavity Design, Fabrication and Test Plans

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burrill, Andrew; Anders, W; Frahm, A.

    2014-12-01

    The bERLinPro project, a 100 mA, 50 MeV superconducting RF (SRF) Energy Recovery Linac (ERL) is under construction at Helmholtz-Zentrum Berlin for the purpose of studying the technical challenges and physics of operating a high current, c.w., 1.3 GHz ERL. This machine will utilize three unique SRF cryomodules for the injector, booster and linac module respectively. The booster cryomodule will contain three 2-cell SRF cavities, based on the original design by Cornell University, and will be equipped with twin 115 kW RF power couplers in order to provide the appropriate acceleration to the high current electron beam. This paper willmore » review the status of the fabrication of the 4 booster cavities that have been built for this project by Jefferson Laboratory and look at the challenges presented by the incorporation of fundamental power couplers capable of delivering 115 kW. The test plan for the cavities and couplers will be given along with a brief overview of the cryomodule design.« less

  10. NASA SLS Booster Nozzle Plug Pieces Fly During Test

    NASA Image and Video Library

    2016-06-28

    On June 28, a test version of the booster that will help power NASA's new rocket, the Space Launch System, fired up at nearly 6,000 degrees Fahrenheit for a successful, two-minute qualification test at Orbital ATK's test facilities in Promontory, Utah. This video shows the booster's nozzle plug intentionally breaking apart. The smoky ring coming off the booster is condensed water vapor created by a pressure difference between the motor gas and normal air. The nozzle plug is an environmental barrier to prevent heat, dust and moisture from getting inside the booster before it ignites. The plug isn't always part of a static test but was included on this one due to changes made to the hardware. The foam on the plug is denser than previous NASA launch vehicles, as the engines are now in the same plane as the boosters. A numbered grid was placed on the exterior of the plug before the test so the pieces retrieved could support plug breakup assessment and reconstruction. Along with video, collecting the pieces helps determine the size and speed of them when they break apart. Nozzle plug pieces were found as far as 1,500 to 2,000 feet away from the booster. This is the last full-scale qualification test for the booster before the first, uncrewed flight of SLS with the Orion spacecraft in 2018.

  11. Prevalence and predictors of booster seat use in Alberta, Canada.

    PubMed

    Golonka, Richard P; Dobbs, Bonnie M; Rowe, Brian H; Voaklander, Don

    2016-08-15

    To determine the prevalence of booster seat misuse in a Canadian province and identify determinants of non-use. A cross-sectional study using parking lot interviews and in-vehicle restraint inspections by trained staff was conducted at 67 randomly selected childcare centres across Alberta. Only booster-eligible children were included in this analysis. Odds ratios (OR) and 95% confidence intervals (CI) are reported using unadjusted and adjusted logistic regression. Overall, 23% of children were not in a booster seat, and in 31.8% of cases there was evidence of at least one misuse. Non-use increased significantly by age, from 22.2% for children 2 years of age to 47.8% for children 7 years of age (p = 0.02). Children who were at significantly increased risk of booster seat non-use were those in vehicles with drivers who could not recall the booster seat to seatbelt transition point (OR: 4.54; 95% CI: 2.05-10.06) or drivers who were under the age of 30 (OR: 3.54; 95% CI: 1.45-8.62). A front row seating position was also associated with significantly higher risk of nonuse (OR: 18.00; 95% CI: 2.78-116.56). Children in vehicles with grandparent drivers exhibited significantly decreased risk of booster seat non-use (OR: 0.21; 95% CI: 0.05-0.85). Messaging should continue to stress that the front seat is not a safe place for any child under the age of 9 as well as remind drivers of the booster seat to seatbelt transition point, with additional emphasis placed on appealing to parents under the age of 30. Future research should focus on the most effective means of communicating booster seat information to this group. Enacting mandatory booster seat legislation would be an important step to increase both awareness and proper use of booster seats in Alberta.

  12. Fiber Lasers and Amplifiers for Space-based Science and Exploration

    NASA Technical Reports Server (NTRS)

    Yu, Anthony W.; Krainak, Michael A.; Stephen, Mark A.; Chen, Jeffrey R.; Coyle, Barry; Numata, Kenji; Camp, Jordan; Abshire, James B.; Allan, Graham R.; Li, Steven X.; hide

    2012-01-01

    We present current and near-term uses of high-power fiber lasers and amplifiers for NASA science and spacecraft applications. Fiber lasers and amplifiers offer numerous advantages for the deployment of instruments on exploration and science remote sensing satellites. Ground-based and airborne systems provide an evolutionary path to space and a means for calibration and verification of space-borne systems. NASA fiber-laser-based instruments include laser sounders and lidars for measuring atmospheric carbon dioxide, oxygen, water vapor and methane and a pulsed or pseudo-noise (PN) code laser ranging system in the near infrared (NIR) wavelength band. The associated fiber transmitters include high-power erbium, ytterbium, and neodymium systems and a fiber laser pumped optical parametric oscillator. We discuss recent experimental progress on these systems and instrument prototypes for ongoing development efforts.

  13. Counterrotatable booster compressor assembly for a gas turbine engine

    NASA Technical Reports Server (NTRS)

    Moniz, Thomas Ory (Inventor); Orlando, Robert Joseph (Inventor)

    2004-01-01

    A counterrotatable booster compressor assembly for a gas turbine engine having a counterrotatable fan section with a first fan blade row connected to a first drive shaft and a second fan blade row axially spaced from the first fan blade row and connected to a second drive shaft, the counterrotatable booster compressor assembly including a first compressor blade row connected to the first drive shaft and a second compressor blade row interdigitated with the first compressor blade row and connected to the second drive shaft. A portion of each fan blade of the second fan blade row extends through a flowpath of the counterrotatable booster compressor so as to function as a compressor blade in the second compressor blade row. The counterrotatable booster compressor further includes a first platform member integral with each fan blade of the second fan blade row at a first location so as to form an inner flowpath for the counterrotatable booster compressor and a second platform member integral with each fan blade of the second fan blade row at a second location so as to form an outer flowpath for the counterrotatable booster compressor.

  14. A 160 W single-frequency laser based on an active tapered double-clad fiber amplifier

    NASA Astrophysics Data System (ADS)

    Trikshev, A. I.; Kurkov, A. S.; Tsvetkov, V. B.; Filatova, S. A.; Kertulla, J.; Filippov, V.; Chamorovskiy, Yu K.; Okhotnikov, O. G.

    2013-06-01

    We present a CW single-frequency laser at 1062 nm (linewidth <3 MHz) with 160 W of total output power based on a two stage fiber amplifier. A GTWave fiber is used for the first stage of the amplifier. A tapered double-clad fiber (T-DCF) is used for the second stage of the amplifier. The high output power is achieved due to the amplified spontaneous emission (ASE) filtering and increased stimulated Brillouin scattering (SBS) threshold inherent to the axially non-uniform geometry.

  15. 47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

  16. 47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

  17. 47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

  18. 47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

  19. 47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

  20. Lessons learned for follow-up phone booster counseling calls with substance abusing emergency department patients.

    PubMed

    Donovan, Dennis M; Hatch-Maillette, Mary A; Phares, Melissa M; McGarry, Ernest; Peavy, K Michelle; Taborsky, Julie

    2015-03-01

    Post-visit "booster" sessions have been recommended to augment the impact of brief interventions delivered in the emergency department (ED). This paper, which focuses on implementation issues, presents descriptive information and interventionists' qualitative perspectives on providing brief interventions over the phone, challenges, "lessons learned", and recommendations for others attempting to implement adjunctive booster calls. Attempts were made to complete two 20-minute telephone "booster" calls within a week following a patient's ED discharge with 425 patients who screened positive for and had recent problematic substance use other than alcohol or nicotine. Over half (56.2%) of participants completed the initial call; 66.9% of those who received the initial call also completed the second call. Median number of attempts to successfully contact participants for the first and second calls were 4 and 3, respectively. Each completed call lasted an average of about 22 minutes. Common challenges/barriers identified by booster callers included unstable housing, limited phone access, unavailability due to additional treatment, lack of compensation for booster calls, and booster calls coming from an area code different than the participants' locale and from someone other than ED staff. Specific recommendations are presented with respect to implementing a successful centralized adjunctive booster call system. Future use of booster calls might be informed by research on contingency management (e.g., incentivizing call completions), smoking cessation quitlines, and phone-based continuing care for substance abuse patients. Future research needs to evaluate the incremental benefit of adjunctive booster calls on outcomes over and above that of brief motivational interventions delivered in the ED setting. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Modeling of induction-linac based free-electron laser amplifiers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jong, R.A.; Fawley, W.M.; Scharlemann, E.T.

    We describe the modeling of an induction-linac based free-electron laser (IFEL) amplifier for producing multimegawatt levels of microwave power. We have used the Lawrence Livermore National Laboratory (LLNL) free-electron laser simulation code, FRED, and the simulation code for sideband calculations, GINGER for this study. For IFEL amplifiers in the frequency range of interest (200 to 600 GHz), we have devised a wiggler design strategy which incorporates a tapering algorithm that is suitable for free-electron laser (FEL) systems with moderate space-charge effects and that minimizes spontaneous noise growth at frequencies below the fundamental, while enhancing the growth of the signal atmore » the fundamental. In addition, engineering design considerations of the waveguide wall loading and electron beam fill factor in the waveguide set limits on the waveguide dimensions, the wiggler magnet gap spacing, the wiggler period, and the minimum magnetic field strength in the tapered region of the wiggler. As an example, we shall describe an FEL amplifier designed to produce an average power of about 10 MW at a frequency of 280 GHz to be used for electron cyclotron resonance heating of tokamak fusion devices. 17 refs., 4 figs.« less

  2. Long-term/strategic scenario for reusable booster stages

    NASA Astrophysics Data System (ADS)

    Sippel, Martin; Manfletti, Chiara; Burkhardt, Holger

    2006-02-01

    This paper describes the final design status of a partially reusable space transportation system which has been under study for five years within the German future launcher technology research program ASTRA. It consists of dual booster stages, which are attached to an advanced expendable core. The design of the reference liquid fly-back boosters (LFBB) is focused on LOX/LH2 propellant and a future advanced gas-generator cycle rocket motor. The preliminary design study was performed in close cooperation between DLR and the German space industry. The paper's first part describes recent progress in the design of this reusable booster stage. The second part of the paper assesses a long-term, strategic scenario of the reusable stage's operation. The general idea is the gradual evolution of the above mentioned basic fly-back booster vehicle into three space transportation systems performing different tasks: Reusable First Stage for a small launcher application, successive development to a fully reusable TSTO, and booster for a super-heavy-lift rocket to support an ambitious space flight program like manned Mars missions. The assessment addresses questions of technical sanity, preliminary sizing and performance issues and, where applicable, examines alternative options.

  3. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – The core booster for the United Launch Alliance Delta IV heavy for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft, was transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station in Florida. The core booster and starboard booster arrived by barge at the U.S. Army Outpost wharf at Port Canaveral. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  4. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – A barge arrives at the U.S. Army Outpost wharf at Port Canaveral in Florida, carrying two of the three United Launch Alliance Delta IV heavy boosters for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft. The core booster and starboard booster will be offloaded and then transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  5. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – Two of the three United Launch Alliance Delta IV heavy boosters for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft, have arrived by barge at the U.S. Army Outpost wharf at Port Canaveral in Florida. The core booster and starboard booster will be offloaded and then transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  6. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – Two of the three United Launch Alliance Delta IV heavy boosters for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft, arrived by barge at the U.S. Army Outpost wharf at Port Canaveral in Florida. The core booster and starboard booster were offloaded and are being transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  7. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – Two of the three United Launch Alliance Delta IV heavy boosters for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft, arrived by barge at the U.S. Army Outpost wharf at Port Canaveral in Florida. The core booster, shown in this photo, and starboard booster were offloaded and will be transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  8. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – Two of the three United Launch Alliance Delta IV heavy boosters for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft, have arrived by barge at the U.S. Army Outpost wharf at Port Canaveral in Florida. The core booster and starboard booster are being offloaded and will be transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  9. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – Two of the three United Launch Alliance Delta IV heavy boosters for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft, arrived by barge at the U.S. Army Outpost wharf at Port Canaveral in Florida. The core booster and starboard booster have been offloaded and will be transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  10. Orion Core Stage & Booster Offload, Move to HIF

    NASA Image and Video Library

    2014-03-04

    CAPE CANAVERAL, Fla. – Two of the three United Launch Alliance Delta IV heavy boosters for NASA’s upcoming Exploration Flight Test-1, or EFT-1, mission with the Orion spacecraft, arrived by barge at the U.S. Army Outpost wharf at Port Canaveral in Florida. The core booster, shown in this photo, and starboard booster were offloaded and transported to the Horizontal Integration Facility, or HIF, at Space Launch Complex 37 on Cape Canaveral Air Force Station. The port booster and the upper stage are planned to be shipped to Cape Canaveral in April. At the HIF, all three boosters will be processed and checked out before being moved to the nearby launch pad and hoisted into position. During the EFT-1 mission, Orion will travel farther into space than any human spacecraft has gone in more than 40 years. The data gathered during the flight will influence design decisions, validate existing computer models and innovative new approaches to space systems development, as well as reduce overall mission risks and costs for later Orion flights. Liftoff of Orion on EFT-1 is planned for fall 2014. Photo credit: NASA/Kim Shiflett

  11. Booster Vaccination: The Role of Reduced Antigen Content Vaccines as a Preschool Booster

    PubMed Central

    Conversano, Michele; Zivelonghi, Giambattista; Zoppi, Giorgio

    2014-01-01

    The need for boosters for tetanus, diphtheria, pertussis, and polio, starting from preschool age, is related to the waning immune protection conferred by vaccination, the elimination/reduction of natural boosters due to large-scale immunization programs, and the possibility of reintroduction of wild agents from endemic areas. Taking into account the relevance of safety/tolerability in the compliance with vaccination among the population, it have been assessed whether today enough scientific evidences are available to support the use of dTap-IPV booster in preschool age. The review of the literature was conducted using the PubMed search engine. A total of 41 works has been selected; besides, the documentation produced by the World Health Organization, the European Centre for Disease Control, and the Italian Ministry of Health has been consulted. Many recent papers confirm the opportunity to use a low antigenic dose vaccine starting from 4 to 6 years of age. There is also evidence that 10 years after immunization the rate of seroprotected subjects against diphtheria does not differ significantly between those vaccinated with paediatric dose (DTaP) or reduced dose (dTaP or dTap) product. The dTpa vaccine is highly immunogenic for diphtheria toxoids regardless of prior vaccination history (2 + 1 and 3 + 1 schedules). PMID:24678509

  12. Booster Seat Effectiveness Among Older Children: Evidence From Washington State.

    PubMed

    Anderson, D Mark; Carlson, Lindsay L; Rees, Daniel I

    2017-08-01

    The American Academy of Pediatrics has recommended that children as old as 12 years use a booster seat when riding in motor vehicles, yet little is known about booster seat effectiveness when used by older children. This study estimated the association between booster use and injuries among children aged 8-12 years who were involved in motor vehicle crashes. Researchers analyzed data on all motor vehicle crashes involving children aged 8-12 years reported to the Washington State Department of Transportation from 2002 to 2015. Data were collected in 2015 and analyzed in 2016. Children who were in a booster seat were compared with children restrained by a seat belt alone. Logistic regression was used to adjust for potential confounders. In unadjusted models, booster use was associated with a 29% reduction in the odds of experiencing any injury versus riding in a seat belt alone (OR=0.709, 95% CI=0.675, 0.745). In models adjusted for potential confounders, booster use was associated with a 19% reduction in the odds of any injury relative to riding in a seat belt alone (OR=0.814, 95% CI=0.749, 0.884). The risk of experiencing an incapacitating/fatal injury was not associated with booster use. Children aged 8-12 years involved in a motor vehicle crash are less likely to be injured if in a booster than if restrained by a seat belt alone. Because only 10% of U.S. children aged 8-12 years use booster seats, policies encouraging their use could lead to fewer injuries. Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  13. Atlas Centaur Rocket With Reusable Booster Engines

    NASA Technical Reports Server (NTRS)

    Martin, James A.

    1993-01-01

    Proposed modification of Atlas Centaur enables reuse of booster engines. Includes replacement of current booster engines with engine of new design in which hydrogen used for both cooling and generation of power. Use of hydrogen in new engine eliminates coking and clogging and improves performance significantly. Primary advantages: reduction of cost; increased reliability; and increased payload.

  14. Booster propulsion/vehicle impact study

    NASA Technical Reports Server (NTRS)

    Weldon, Vincent; Dunn, Michael; Fink, Lawrence; Phillips, Dwight; Wetzel, Eric

    1988-01-01

    The use of hydrogen RP-1, propane, and methane as fuels for booster engines of launch vehicles is discussed. An automated procedure for integrated launch vehicle, engine sizing, and design optimization was used to define two stage and single stage concepts for minimum dry weight. The two stage vehicles were unmanned and used a flyback booster and partially reusable orbiter. The single stage designs were fully reusable, manned flyback vehicles. Comparisons of these vehicle designs, showing the effects of using different fuels, as well as sensitivity and trending data, are presented. In addition, the automated design technique utilized for the study is described.

  15. Parametric Amplifier and Oscillator Based on Josephson Junction Circuitry

    NASA Astrophysics Data System (ADS)

    Yamamoto, T.; Koshino, K.; Nakamura, Y.

    While the demand for low-noise amplification is ubiquitous, applications where the quantum-limited noise performance is indispensable are not very common. Microwave parametric amplifiers with near quantum-limited noise performance were first demonstrated more than 20 years ago. However, there had been little effort until recently to improve the performance or the ease of use of these amplifiers, partly because of a lack of any urgent motivation. The emergence of the field of quantum information processing in superconducting systems has changed this situation dramatically. The need to reliably read out the state of a given qubit using a very weak microwave probe within a very short time has led to renewed interest in these quantum-limited microwave amplifiers, which are already widely used as tools in this field. Here, we describe the quantum mechanical theory for one particular parametric amplifier design, called the flux-driven Josephson parametric amplifier, which we developed in 2008. The theory predicts the performance of this parametric amplifier, including its gain, bandwidth, and noise temperature. We also present the phase detection capability of this amplifier when it is operated with a pump power that is above the threshold, i.e., as a parametric phase-locked oscillator or parametron.

  16. Solid rocket booster thermal protection system materials development. [space shuttle boosters

    NASA Technical Reports Server (NTRS)

    Dean, W. G.

    1978-01-01

    A complete run log of all tests conducted in the NASA-MSFC hot gas test facility during the development of materials for the space shuttle solid rocket booster thermal protection system are presented. Lists of technical reports and drawings generated under the contract are included.

  17. Integrated hydraulic booster/tool string technology for unfreezing of stuck downhole strings in horizontal wells

    NASA Astrophysics Data System (ADS)

    Tian, Q. Z.

    2017-12-01

    It is common to use a jarring tool to unfreeze stuck downhole string. However, in a horizontal well, influenced by the friction caused by the deviated section, jarring effect is poor; on the other hand, the forcing point can be located in the horizontal section by a hydraulic booster and the friction can be reduced, but it is time-consuming and easy to break downhole string using a large-tonnage and constant pull force. A hydraulic booster - jar tool string has been developed for unfreezing operation in horizontal wells. The technical solution involves three elements: a two-stage parallel spring cylinder structure for increasing the energy storage capacity of spring accelerators; multiple groups of spring accelerators connected in series to increase the working stroke; a hydraulic booster intensifying jarring force. The integrated unfreezing tool string based on these three elements can effectively overcome the friction caused by a deviated borehole, and thus unfreeze a stuck string with the interaction of the hydraulic booster and the mechanical jar which form an alternatively dynamic load. Experimental results show that the jarring performance parameters of the hydraulic booster-jar unfreezing tool string for the horizontal wells are in accordance with original design requirements. Then field technical parameters were developed based on numerical simulation and experimental data. Field application shows that the hydraulic booster-jar unfreezing tool string is effective to free stuck downhole tools in a horizontal well, and it reduces hook load by 80% and lessens the requirement of workover equipment. This provides a new technology to unfreeze stuck downhole string in a horizontal well.

  18. STS-26 solid rocket booster post flight structural assessment

    NASA Technical Reports Server (NTRS)

    Herda, David A.; Finnegan, Charles J.

    1988-01-01

    A post flight assessment of the Space Shuttle's Solid Rocket Boosters was conducted at the John F. Kennedy Space Center in Florida after the launch of STS-26. The two boosters were inspected for structural damage and the results of this inspection are presented. Overall, the boosters were in good condition. However, there was some minor damage attributed to splash down. Some of this damage is a recurring problem. Explanations of these problems are provided.

  19. NASA's Space Launch System: Developing the World's Most Powerful Solid Booster

    NASA Technical Reports Server (NTRS)

    Priskos, Alex

    2016-01-01

    NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are under way with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances the odds of mission success. SLS will be powered by four liquid fuel RS-25 engines and two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant

  20. Left atrial booster function in valvular heart disease.

    PubMed

    Heidenreich, F P; Shaver, J A; Thompson, M E; Leonard, J J

    1970-09-01

    This study was designed to assess atrial booster pump action in valvular heart disease and to dissect booster pump from reservoir-conduit functions. In five patients with aortic stenosis and six with mitral stenosis, sequential atrioventricular (A-V) pacing was instituted during the course of diagnostic cardiac catheterization. Continuous recording of valvular gradient allowed estimation of flow for each cardiac cycle by transposition of the Gorlin formula. Left ventricular ejection time and left ventricular stroke work in aortic stenosis or left ventricular mean systolic pressure in mitral stenosis were also determined. Control observations were recorded during sequential A-V pacing with well-timed atrial systole. Cardiac cycles were then produced with no atrial contraction but undisturbed atrial reservoir function by intermittently interrupting the atrial pacing stimulus during sequential A-V pacing. This intervention significantly reduced valvular gradient, flow, left ventricular ejection time, and left ventricular mean systolic pressure or stroke work. Cardiac cycles were then produced with atrial booster action eliminated by instituting synchronous A-V pacing. The resultant simultaneous contraction of the atrium and ventricle not only eliminated effective atrial systole but also placed atrial systole during the normal period of atrial reservoir function. This also significantly reduced all the hemodynamic measurements. However, comparison of the magnitude of change from these two different pacing interventions showed no greater impairment of hemodynamic state when both booster pump action and reservoir function were impaired than when booster pump action alone was impaired. The study confirms the potential benefit of well placed atrial booster pump action in valvular heart disease in man.

  1. Hypersonic aerothermal characteristics of a manned low finenes ratio shuttle booster

    NASA Technical Reports Server (NTRS)

    Bernot, P. T.; Throckmorton, D. A.

    1972-01-01

    An investigation of a winged booster model having canards and an ascent configuration comprised of the booster mounted in tandem with an orbiter model has been conducted at Mach 10.2 in the continuous flow hypersonic tunnel. Longitudinal and lateral directional force characteristics were obtained over angle of attack ranges of -12 deg to 60 deg for the booster and -11 deg to 11 deg for the ascent configuration. Interference heating effects on the booster using the phase-change coating technique were determined at 0 deg angle of attack. Some oil flow photographs of the isolated booster and orbiter and ascent configuration are also presented.

  2. 104. SIGNAL CONDITIONERS FOR BOOSTER INSTRUMENTATION, SOUTHWEST SIDE OF LANDLINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    104. SIGNAL CONDITIONERS FOR BOOSTER INSTRUMENTATION, SOUTHWEST SIDE OF LANDLINE INSTRUMENTATION ROOM (106), LSB (BLDG. 770) - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  3. Solid-liquid staged combustion space boosters

    NASA Technical Reports Server (NTRS)

    Culver, D. W.

    1990-01-01

    NASA has begun to evaluate solid-liquid hybrid propulsion for launch vehicle booster. A three-phase program was outlined to identify, acquire, and demonstrate technology needed to approximate solid and liquid propulsion state of the art. Aerojet has completed a Phase 1 study and recommends a solid-liquid staged combustion concept in which turbopump fed LO2 is burned with fuel-rich solid propellant effluent in aft-mounted thrust chambers.These reasonably sized thrust chambers are LO2 regeneratively cooled, supplemented with fuel-rich barrier cooling. Turbopumps are driven by the resulting GO2 coolant in an expander-bleed-burnoff cycle. Turbine exhaust pressurizes the LO2 tankage directly, and the excess is bled into supersonic nozzle splitlines, where it combusts with the fuel rich boundary layer. Thrust vector control is enhanced by supersonic nozzle movement on flexseal mounts. Every hybrid solid-liquid concept examined improves booster energy management and launch propellant safety compared to current solid boosters. Solid-liquid staged combustion improves hybrid performance by improving both combustion efficiency and combustion stability, especially important for large boosters. These improvements result from careful fluid management and use of smaller combustors. The study shows NASA safety, reliability, cost, and performance criteria are best met with this concept, wherein simple hardware relies on several separate emerging technologies, all of which have been demonstrated successfully.

  4. Closeup view of the Solid Rocket Booster Frustum and Nose ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster Frustum and Nose Cap assembly undergoing preparations and assembly procedures in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center. The Nose Cap contains the Pilot and Drogue Chutes and the Frustum contains the three Main Parachutes, Altitude Switches and forward booster Separation Motors. In this view the assembly is rotated so that the four Separation Motors are in view and aligned with the approximate centerline of the image. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  5. Liquid Rocket Booster Study. Volume 2, Book 1

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The recommended Liquid Rocket Booster (LRB) concept is shown which uses a common main engine with the Advanced Launch System (ALS) which burns LO2 and LH2. The central rationale is based on the belief that the U.S. can only afford one big new rocket engine development in the 1990's. A LO2/LH2 engine in the half million pound thrust class could satisfy STS LRB, ALS, and Shuttle C (instead of SSMEs). Development costs and higher production rates can be shared by NASA and USAF. If the ALS program does not occur, the LO2/RP-1 propellants would produce slight lower costs for and STS LRB. When the planned Booster Engine portion of the Civil Space Transportation Initiatives has provided data on large pressure fed LO2/RP-1 engines, then the choice should be reevaluated.

  6. Space shuttle booster separation motor design

    NASA Technical Reports Server (NTRS)

    Smith, G. W.; Chase, C. A.

    1976-01-01

    The separation characteristics of the space shuttle solid rocket boosters (SRBs) are introduced along with the system level requirements for the booster separation motors (BSMs). These system requirements are then translated into specific motor requirements that control the design of the BSM. Each motor component is discussed including its geometry, material selection, and fabrication process. Also discussed is the propellant selection, grain design, and performance capabilities of the motor. The upcoming test program to develop and qualify the motor is outlined.

  7. A comparison of self-report and direct observation of booster seat use in Latino families.

    PubMed

    Quistberg, D Alex; Lozano, Paula; Mack, Christopher D; Schwartz, Rachel; Ebel, Beth E

    2010-08-01

    To develop a reliable self-report tool for measuring child booster seat use among Latino families. Cross-sectional and observational survey of a convenience sample. Five retail stores in King County, Washington. 50 parents of children 4-8 years old that self-identified as Latino or Hispanic. Parent-reported measures of how often the child uses a booster seat, if the child used a booster seat on the last trip, how often the child complains about using a booster seat, how often the child asks to not use a booster seat, and how often other families they know use a booster seat. Observed booster seat use by child. 26 children (52%) were observed using a booster seat. Parent-reported booster seat use was a poor predictor of observed booster seat use. Although 34 parents reported that their child 'always' uses a booster seat, 8 (24%) of these children were not using a booster seat. A logistic model to predict booster seat use had a sensitivity of 81% and a specificity of 71%, and misclassified 24% of the participants' observed use. Reliance on parent-reported booster seat use significantly overstated observed booster seat use in the study. Among this study population, accurate determination of booster seat use required direct observation.

  8. SQUID amplifiers for axion search experiments

    NASA Astrophysics Data System (ADS)

    Matlashov, Andrei; Schmelz, Matthias; Zakosarenko, Vyacheslav; Stolz, Ronny; Semertzidis, Yannis K.

    2018-04-01

    In the experiments for dark-matter QCD-axion searches, very weak microwave signals from a low-temperature High-Q resonant cavity should be detected using the highest sensitivity. The best commercial low-noise cryogenic semiconductor amplifiers based on high electron mobility transistors have a lowest noise temperature above 1.0 K, even if they are cooled well below 1 K. Superconducting quantum interference devices can work as microwave amplifiers with temperature noise close to the standard quantum limit. Previous SQUID-based RF amplifiers designed for axion search experiments have a microstrip resonant input coil and are thus called micro-strip SQUID amplifiers or MSAs. Due to the resonant input coupling they usually have narrow bandwidth. In this paper we report on a SQUID-based wideband microwave amplifier fabricated using sub-micron size Josephson junctions with very low capacitance. A single amplifier can be used in a frequency range of approximately 1-5 GHz.

  9. Solid Rocket Booster Structural Test Article

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The structural test article to be used in the solid rocket booster (SRB) structural and load verification tests is being assembled in a high bay building of the Marshall Space Flight Center (MSFC). The Shuttle's two SRB's are the largest solids ever built and the first designed for refurbishment and reuse. Standing nearly 150-feet high, the twin boosters provide the majority of thrust for the first two minutes of flight, about 5.8 million pounds, augmenting the Shuttle's main propulsion system during liftoff. The major design drivers for the solid rocket motors (SRM's) were high thrust and reuse. The desired thrust was achieved by using state-of-the-art solid propellant and by using a long cylindrical motor with a specific core design that allows the propellant to burn in a carefully controlled marner. At burnout, the boosters separate from the external tank and drop by parachute to the ocean for recovery and subsequent refurbishment.

  10. NASA's Space Launch System Advanced Booster Engineering Demonstration and Risk Reduction Efforts

    NASA Technical Reports Server (NTRS)

    Crumbly, Christopher M.; May, Todd; Dumbacher, Daniel

    2012-01-01

    The National Aeronautics and Space Administration (NASA) formally initiated the Space Launch System (SLS) development in September 2011, with the approval of the program s acquisition plan, which engages the current workforce and infrastructure to deliver an initial 70 metric ton (t) SLS capability in 2017, while using planned block upgrades to evolve to a full 130 t capability after 2021. A key component of the acquisition plan is a three-phased approach for the first stage boosters. The first phase is to complete the development of the Ares and Space Shuttle heritage 5-segment solid rocket boosters for initial exploration missions in 2017 and 2021. The second phase in the booster acquisition plan is the Advanced Booster Risk Reduction and/or Engineering Demonstration NASA Research Announcement (NRA), which was recently awarded after a full and open competition. The NRA was released to industry on February 9, 2012, and its stated intent was to reduce risks leading to an affordable Advanced Booster and to enable competition. The third and final phase will be a full and open competition for Design, Development, Test, and Evaluation (DDT&E) of the Advanced Boosters. There are no existing boosters that can meet the performance requirements for the 130 t class SLS. The expected thrust class of the Advanced Boosters is potentially double the current 5-segment solid rocket booster capability. These new boosters will enable the flexible path approach to space exploration beyond Earth orbit, opening up vast opportunities including near-Earth asteroids, Lagrange Points, and Mars. This evolved capability offers large volume for science missions and payloads, will be modular and flexible, and will be right-sized for mission requirements. NASA developed the Advanced Booster Engineering Demonstration and/or Risk Reduction NRA to seek industry participation in reducing risks leading to an affordable Advanced Booster that meets the SLS performance requirements. Demonstrations and

  11. InSight Atlas V Booster Transport

    NASA Image and Video Library

    2018-03-02

    A United Launch Alliance Atlas V booster is transported to Space Launch Complex 3 at Vandenberg Air Force Base in California. The rocket will launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

  12. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – Workers prepare to lift the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, from its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  13. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is lifted from its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  14. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-19

    VANDENBERG AIR FORCE BASE, Calif. – The truck transporting the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, backs toward the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  15. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is lowered onto a transportation hardware cradle in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  16. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – Workers secure the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, onto a transportation hardware cradle in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  17. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, and its transportation hardware cradle roll into the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  18. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is positioned inside the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  19. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is towed to the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  20. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-19

    VANDENBERG AIR FORCE BASE, Calif. – Preparations are underway to offload the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, into the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  1. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, arrives at the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  2. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is suspended above its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  3. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-19

    VANDENBERG AIR FORCE BASE, Calif. – The truck transporting the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, arrives outside the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  4. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, secured in a transportation hardware cradle, is towed to the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  5. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – A worker maneuvers the transporter towing the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, at the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  6. SIMULATIONS OF BOOSTER INJECTION EFFICIENCY FOR THE APS-UPGRADE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Calvey, J.; Borland, M.; Harkay, K.

    2017-06-25

    The APS-Upgrade will require the injector chain to provide high single bunch charge for swap-out injection. One possible limiting factor to achieving this is an observed reduction of injection efficiency into the booster synchrotron at high charge. We have simulated booster injection using the particle tracking code elegant, including a model for the booster impedance and beam loading in the RF cavities. The simulations point to two possible causes for reduced efficiency: energy oscillations leading to losses at high dispersion locations, and a vertical beam size blowup caused by ions in the Particle Accumulator Ring. We also show that themore » efficiency is much higher in an alternate booster lattice with smaller vertical beta function and zero dispersion in the straight sections.« less

  7. Thermal and dynamic range characterization of a photonics-based RF amplifier

    NASA Astrophysics Data System (ADS)

    Noque, D. F.; Borges, R. M.; Muniz, A. L. M.; Bogoni, A.; Cerqueira S., Arismar, Jr.

    2018-05-01

    This work reports a thermal and dynamic range characterization of an ultra-wideband photonics-based RF amplifier for microwave and mm-waves future 5G optical-wireless networks. The proposed technology applies the four-wave mixing nonlinear effect to provide RF amplification in analog and digital radio-over-fiber systems. The experimental analysis from 300 kHz to 50 GHz takes into account different figures of merit, such as RF gain, spurious-free dynamic range and RF output power stability as a function of temperature. The thermal characterization from -10 to +70 °C demonstrates a 27 dB flat photonics-assisted RF gain over the entire frequency range under real operational conditions of a base station for illustrating the feasibility of the photonics-assisted RF amplifier for 5G networks.

  8. 7. VIEW OF BOOSTER STATION 3, FACING NORTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW OF BOOSTER STATION 3, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  9. 2. VIEW OF BOOSTER STATION 1, FACING NORTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW OF BOOSTER STATION 1, FACING NORTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  10. 11. VIEW OF BOOSTER STATION 4, FACING SOUTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. VIEW OF BOOSTER STATION 4, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  11. 10. VIEW OF BOOSTER STATION 4, FACING NORTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. VIEW OF BOOSTER STATION 4, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  12. 1. VIEW OF BOOSTER STATION 1, FACING SOUTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF BOOSTER STATION 1, FACING SOUTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  13. 8. VIEW OF BOOSTER STATION 3, FACING SOUTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF BOOSTER STATION 3, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  14. 4. VIEW OF BOOSTER STATION 2, FACING NORTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW OF BOOSTER STATION 2, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  15. 5. VIEW OF BOOSTER STATION 2, FACING SOUTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW OF BOOSTER STATION 2, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  16. Booster Synchrotron RF System Upgrade for SPEAR3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, Sanghyun; /SLAC; Corbett, Jeff

    2012-07-06

    Recent progress at the SPEAR3 includes the increase in stored current from 100 mA to 200 mA and top-off injection to allow beamlines to stay open during injection. Presently the booster injects 3.0 GeV beam to SPEAR3 three times a day. The stored beam decays to about 150 mA between the injections. The growing user demands are to increase the stored current to the design value of 500 mA, and to maintain it at a constant value within a percent or so. To achieve this goal the booster must inject once every few minutes. For improved injection efficiency, all RFmore » systems at the linac, booster and SPEAR3 need to be phase-locked. The present booster RF system is basically a copy of the SPEAR2 RF system with 358.5 MHz and 40 kW peak RF power driving a 5-cell RF cavity for 1.0 MV gap voltage. These requirements entail a booster RF system upgrade to a scaled down version of the SPEAR3 RF system of 476.3 MHz with 1.2 MW cw klystron output power capabilities. We will analyze each subsystem option for their merits within budgetary and geometric space constraints. A substantial portion of the system will come from the decommissioned PEP-II RF stations.« less

  17. Photodarkening kinetics in a high-power YDFA versus CW or short-pulse seed conditions

    NASA Astrophysics Data System (ADS)

    Jolly, Alain; Vinçont, Cyril; Boullet, Johan

    2017-02-01

    We propose an innovating model to describe the kinetics of competing photo-darkening and photo-bleaching phenomena in high-power, Ytterbium-Doped-Fibre-Amplifiers. This model makes use of aggregated species of trivalent Ytterbium and divalent ions, which operate as primarily efficient color-centers. This ensures multi-photon excitation, partly from the pump and partly from the signal. The fit of numerical computations with dedicated experiments help to validate our theoretical assumptions, in the definition of the involved physics. Potential applications of this study include further discussions for the selection of processing options with fibre-manufacturers and the optimization of operating conditions.

  18. 9. VIEW OF BOOSTER STATION 3 INTERIOR, FACING NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. VIEW OF BOOSTER STATION 3 INTERIOR, FACING NORTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  19. 6. VIEW OF BOOSTER STATION 2 INTERIOR, FACING WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF BOOSTER STATION 2 INTERIOR, FACING WEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  20. 12. VIEW OF BOOSTER STATION 4 INTERIOR, FACING SOUTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. VIEW OF BOOSTER STATION 4 INTERIOR, FACING SOUTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  1. 3. VIEW OF BOOSTER STATION 1 INTERIOR, FACING EAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW OF BOOSTER STATION 1 INTERIOR, FACING EAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  2. 47 CFR 90.219 - Use of signal boosters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., tunnels, shielded outdoor areas and other locations where these signals would otherwise be too weak for... with the rules in this paragraph. (1) Signal boosters may be used to improve coverage in weak signal... 47 Telecommunication 5 2013-10-01 2013-10-01 false Use of signal boosters. 90.219 Section 90.219...

  3. 47 CFR 90.219 - Use of signal boosters.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... fill in only weak signal areas and cannot extend the system's normal signal coverage area. (b) Class A... 47 Telecommunication 5 2010-10-01 2010-10-01 false Use of signal boosters. 90.219 Section 90.219... MOBILE RADIO SERVICES General Technical Standards § 90.219 Use of signal boosters. Licensees authorized...

  4. 47 CFR 90.219 - Use of signal boosters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., tunnels, shielded outdoor areas and other locations where these signals would otherwise be too weak for... with the rules in this paragraph. (1) Signal boosters may be used to improve coverage in weak signal... 47 Telecommunication 5 2014-10-01 2014-10-01 false Use of signal boosters. 90.219 Section 90.219...

  5. 47 CFR 90.219 - Use of signal boosters.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... fill in only weak signal areas and cannot extend the system's normal signal coverage area. (b) Class A... 47 Telecommunication 5 2011-10-01 2011-10-01 false Use of signal boosters. 90.219 Section 90.219... MOBILE RADIO SERVICES General Technical Standards § 90.219 Use of signal boosters. Licensees authorized...

  6. 47 CFR 90.219 - Use of signal boosters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... fill in only weak signal areas and cannot extend the system's normal signal coverage area. (b) Class A... 47 Telecommunication 5 2012-10-01 2012-10-01 false Use of signal boosters. 90.219 Section 90.219... MOBILE RADIO SERVICES General Technical Standards § 90.219 Use of signal boosters. Licensees authorized...

  7. InSight Atlas V Booster Transport

    NASA Image and Video Library

    2018-03-02

    A United Launch Alliance Atlas V booster departs building 7525 at Vandenberg Air Force Base in California on its way to Space Launch Complex 3. The rocket will launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

  8. Noise spectra in balanced optical detectors based on transimpedance amplifiers.

    PubMed

    Masalov, A V; Kuzhamuratov, A; Lvovsky, A I

    2017-11-01

    We present a thorough theoretical analysis and experimental study of the shot and electronic noise spectra of a balanced optical detector based on an operational amplifier connected in a transimpedance scheme. We identify and quantify the primary parameters responsible for the limitations of the circuit, in particular, the bandwidth and shot-to-electronic noise clearance. We find that the shot noise spectrum can be made consistent with the second-order Butterworth filter, while the electronic noise grows linearly with the second power of the frequency. Good agreement between the theory and experiment is observed; however, the capacitances of the operational amplifier input and the photodiodes appear significantly higher than those specified in manufacturers' datasheets. This observation is confirmed by independent tests.

  9. Noise spectra in balanced optical detectors based on transimpedance amplifiers

    NASA Astrophysics Data System (ADS)

    Masalov, A. V.; Kuzhamuratov, A.; Lvovsky, A. I.

    2017-11-01

    We present a thorough theoretical analysis and experimental study of the shot and electronic noise spectra of a balanced optical detector based on an operational amplifier connected in a transimpedance scheme. We identify and quantify the primary parameters responsible for the limitations of the circuit, in particular, the bandwidth and shot-to-electronic noise clearance. We find that the shot noise spectrum can be made consistent with the second-order Butterworth filter, while the electronic noise grows linearly with the second power of the frequency. Good agreement between the theory and experiment is observed; however, the capacitances of the operational amplifier input and the photodiodes appear significantly higher than those specified in manufacturers' datasheets. This observation is confirmed by independent tests.

  10. OFCC based voltage and transadmittance mode instrumentation amplifier

    NASA Astrophysics Data System (ADS)

    Nand, Deva; Pandey, Neeta; Pandey, Rajeshwari; Tripathi, Prateek; Gola, Prashant

    2017-07-01

    The operational floating current conveyor (OFCC) is a versatile active block due to the availability of both low and high input and output impedance terminals. This paper addresses the realization of OFCC based voltage and transadmittance mode instrumentation amplifiers (VMIA and TAM IA). It employs three OFCCs and seven resistors. The transadmittance mode operation can easily be obtained by simply connecting an OFCC based voltage to current converter at the output. The effect of non-idealities of OFCC, in particular finite transimpedance and tracking error, on system performance is also dealt with and corresponding mathematical expressions are derived. The functional verification is performed through SPICE simulation using CMOS based implementation of OFCC.

  11. Cost Effectiveness of a Shingles Vaccine Booster for Currently Vaccinated Adults in the U.S.

    PubMed

    Le, Phuc; Rothberg, Michael B

    2017-12-01

    The Advisory Committee on Immunization Practices recommends a single dose of the live attenuated herpes zoster vaccine in people aged ≥60 years. Because vaccine-induced protection decreases to zero after 10 years, many vaccinated people will soon be subject to an increased risk of the disease. The study objective was to determine the cost effectiveness of a herpes zoster vaccine booster and its optimal timing among immunocompetent adults first vaccinated at aged ≥60 years. A Markov model was built to follow vaccinated individuals for a lifetime. From the societal perspective, costs and quality-adjusted life years were compared between no booster versus booster options. A booster was given any time between 1 and 20 years after the first dose, and for those who had the first dose at different ages: 60, 70, and 80 years. Because people entered the model already vaccinated, costs and side effects of the first dose were not included. The booster was assumed to have the same efficacy and waning rate as the initial vaccination. Model inputs were based on published literature. A cost effectiveness threshold of $100,000/quality-adjusted life year was used. The analysis was conducted in 2016. Cost effectiveness of a booster varied by age and time since vaccination. The booster cost <$100,000/quality-adjusted life year if given >5 years after the initial dose, but was most cost effective at around 10 years. The finding was robust to wide variations in model inputs. Under current assumptions, a booster dose of herpes zoster vaccine would be cost effective for all vaccinated people 10 years after initial vaccination. Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  12. Note: cryogenic low-noise dc-coupled wideband differential amplifier based on SiGe heterojunction bipolar transistors.

    PubMed

    Beev, Nikolai; Kiviranta, Mikko

    2012-06-01

    Silicon-germanium heterojunction bipolar transistors can be used to construct low-noise cryogenic amplifiers. We present a dc-coupled differential amplifier capable of operating down to 10 K. In this temperature regime it has bandwidth of 15 MHz and noise temperature as low as 1.3 K. When operated at liquid nitrogen temperature of 77 K, the measured noise temperature is lower than 3 K. The amplifier is based on the commercially available transistors NESG3031 and operational amplifier OPA836 and is capable of standalone operation without any additional stages at room temperature.

  13. Large-eddy simulations of a solid-rocket booster jet

    NASA Astrophysics Data System (ADS)

    Paoli, Roberto; Poubeau, Adele; Cariolle, Daniel

    2014-11-01

    Emissions from solid-rocket boosters are responsible for a severe decrease in ozone concentration in the rocket plume during the first hours after a launch. The main source of ozone depletion is due to hydrogen chloride that is converted into chlorine in the high temperature regions of the jet (afterburning). The objective of this study is to evaluate the active chlorine concentration in the plume of a solid-rocket booster using large-eddy simulations. The gas is injected through the entire nozzle of the booster and a local time-stepping method based on coupling multi-instances of a fluid solver is used to extend the computational domain up to 600 nozzle exit diameters. The methodology is validated for a non-reactive case by analyzing the flow characteristics of supersonic co-flowing under expanded jets. Then, the chemistry of chlorine is studied offline using a complex chemistry solver and the LES data extracted from the mean trajectories of sample fluid particles. Finally, the online chemistry is analyzed by means of the multispecies version of the LES solver using a reduced chemistry scheme. The LES are able to capture the mixing of the exhaust with ambient air and the species concentrations, which is also useful to initialize atmospheric simulations on larger domains.

  14. Modeling Longitudinal Dynamics in the Fermilab Booster Synchrotron

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ostiguy, Jean-Francois; Bhat, Chandra; Lebedev, Valeri

    2016-06-01

    The PIP-II project will replace the existing 400 MeV linac with a new, CW-capable, 800 MeV superconducting one. With respect to current operations, a 50% increase in beam intensity in the rapid cycling Booster synchrotron is expected. Booster batches are combined in the Recycler ring; this process limits the allowed longitudinal emittance of the extracted Booster beam. To suppress eddy currents, the Booster has no beam pipe; magnets are evacuated, exposing the beam to core laminations and this has a substantial impact on the longitudinal impedance. Noticeable longitudinal emittance growth is already observed at transition crossing. Operation at higher intensitymore » will likely necessitate mitigation measures. We describe systematic efforts to construct a predictive model for current operating conditions. A longitudinal only code including a laminated wall impedance model, space charge effects, and feedback loops is developed. Parameter validation is performed using detailed measurements of relevant beam, rf and control parameters. An attempt is made to benchmark the code at operationally favorable machine settings.« less

  15. OCO-2 Booster Arrival

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – A worker surveys the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, secured in a transportation hardware cradle, that he delivered to the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  16. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is suspended midair during its transfer from its transportation trailer to a transportation hardware cradle in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  17. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – Workers steady the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, as it is lifted from its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  18. OCO-2 Booster Offload

    NASA Image and Video Library

    2014-03-20

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, rests on a transportation hardware cradle in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California awaiting installation on the pad. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  19. Performance evaluation of DAAF as a booster material using the onionskin test

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Morris, John S; Francois, Elizabeth G; Hooks, Daniel E

    Initiation of insensitive high explosive (IHE) formulations requires the use of a booster explosive in the initiation train. Booster material selection is crucial, as the initiation must reliably function across some spectrum of physical parameters. The interest in Diaminoazoxyfurazan (DAAF) for this application stems from the fact that it possesses many traits of an IHE but is shock sensitive enough to serve as an explosive booster. A hemispherical wave breakout test, termed the onionskin test, is one of the methods used to evaluate the performance of a booster material. The wave breakout time-position history at the surface of a hemisphericalmore » IHE charge is recorded and the relative uniformity of the breakout can be quantitatively compared between booster materials. A series of onionskin tests were performed to investigate breakout and propagation diaminoazoxyfurazan (DAAF) at low temperatures to evaluate ignition and detonation spreading in comparison to other explosives commonly used in booster applications. Some wave perturbation was observed with the DAAF booster in the onionskin tests presented. The results of these tests will be presented and discussed.« less

  20. Booster Main Engine Selection Criteria for the Liquid Fly-Back Booster

    NASA Technical Reports Server (NTRS)

    Ryan, Richard M.; Rothschild, William J.; Christensen, David L.

    1998-01-01

    The Liquid Fly-Back Booster (LFBB) Program seeks to enhance the Space Shuttle system safety performance and economy of operations through the use of an advanced, liquid propellant Booster Main Engine (BME). There are several viable BME candidates that could be suitable for this application. The objective of this study was to identify the key criteria to be applied in selecting among these BME candidates. This study involved an assessment of influences on the overall LFBB utility due to variations in the candidate rocket engines' characteristics. This includes BME impacts on vehicle system weight, perfortnance,design approaches, abort modes, margins of safety, engine-out operations, and maintenance and support concepts. Systems engineering analyses and trade studies were performed to identify the LFBB system level sensitivities to a wide variety of BME related parameters. This presentation summarizes these trade studies and the resulting findings of the LFBB design teams regarding the BME characteristics that most significantly affect the LFBB system. The resulting BME choice should offer the best combination of reliability, performance, reusability, robustness, cost, and risk for the LFBB program.

  1. Booster Main Engine Selection Criteria for the Liquid Fly-Back Booster

    NASA Technical Reports Server (NTRS)

    Ryan, Richard M.; Rothschild, William J.; Christensen, David L.

    1998-01-01

    The Liquid Fly-Back Booster (LFBB) Program seeks to enhance the Space Shuttle system safety, performance and economy of operations through the use of an advanced, liquid propellant Booster Main Engine (BME). There are several viable BME candidates that could be suitable for this application. The objective of this study was to identify the key Criteria to be applied in selecting among these BME candidates. This study involved an assessment of influences on the overall LFBB utility due to variations in the candidate rocket-engines characteristics. This includes BME impacts on vehicle system weight, performance, design approaches, abort modes, margins of safety, engine-out operations, and maintenance and support concepts. Systems engineering analyses and trade studies were performed to identify the LFBB system level sensitivities to a wide variety of BME related parameters. This presentation summarizes these trade studies and the resulting findings of the LFBB design teams regarding the BME characteristics that most significantly affect the LFBB system. The resulting BME choice should offer the best combination of reliability, performance, reusability, robustness, cost, and risk for the LFBB program.

  2. Year 5 Booster Units. The National Literacy Strategy.

    ERIC Educational Resources Information Center

    Department for Education and Employment, London (England).

    The eight units of work in this document are designed to complement existing literacy booster units. Each unit is based on teaching objectives from the National Literacy Strategy Framework. They have been produced with the help of Year 5 teachers and have been trialled with pupils in a range of schools. The units support teachers' work with Year 5…

  3. Liquid rocket booster study. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The purpose of this study was to determine the feasibility of Liquid Rocket Boosters (LRBs) replacing Solid Rocket Boosters on the Space Shuttle program. The major findings are given. The most significant conclusion is that LRBs offer significantly safety and performance advantages over the SRBs currently used by the STS without major impact to the ongoing program.

  4. Space Launch System Accelerated Booster Development Cycle

    NASA Technical Reports Server (NTRS)

    Arockiam, Nicole; Whittecar, William; Edwards, Stephen

    2012-01-01

    With the retirement of the Space Shuttle, NASA is seeking to reinvigorate the national space program and recapture the public s interest in human space exploration by developing missions to the Moon, near-earth asteroids, Lagrange points, Mars, and beyond. The would-be successor to the Space Shuttle, NASA s Constellation Program, planned to take humans back to the Moon by 2020, but due to budgetary constraints was cancelled in 2010 in search of a more "affordable, sustainable, and realistic" concept2. Following a number of studies, the much anticipated Space Launch System (SLS) was unveiled in September of 2011. The SLS core architecture consists of a cryogenic first stage with five Space Shuttle Main Engines (SSMEs), and a cryogenic second stage using a new J-2X engine3. The baseline configuration employs two 5-segment solid rocket boosters to achieve a 70 metric ton payload capability, but a new, more capable booster system will be required to attain the goal of 130 metric tons to orbit. To this end, NASA s Marshall Space Flight Center recently released a NASA Research Announcement (NRA) entitled "Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction." The increased emphasis on affordability is evident in the language used in the NRA, which is focused on risk reduction "leading to an affordable Advanced Booster that meets the evolved capabilities of SLS" and "enabling competition" to "enhance SLS affordability. The purpose of the work presented in this paper is to perform an independent assessment of the elements that make up an affordable and realistic path forward for the SLS booster system, utilizing advanced design methods and technology evaluation techniques. The goal is to identify elements that will enable a more sustainable development program by exploring the trade space of heavy lift booster systems and focusing on affordability, operability, and reliability at the system and subsystem levels5. For this study

  5. Response to booster doses of hepatitis B vaccine among young adults who had received neonatal vaccination.

    PubMed

    Chan, Paul K S; Ngai, Karry L K; Lao, Terence T; Wong, Martin C S; Cheung, Theresa; Yeung, Apple C M; Chan, Martin C W; Luk, Scotty W C

    2014-01-01

    Newborns who have received hepatitis B immunization in 1980s are now young adults joining healthcare disciplines. The need for booster, pre- and post-booster checks becomes a practical question. The aim of this study is to refine the HBV vaccination policy for newly admitted students in the future. A prospective study on medical and nursing school entrants to evaluate hepatitis B serostatus and the response to booster doses among young adults. Among 212 students, 17-23-year-old, born after adoption of neonatal immunization, 2 (0.9%) were HBsAg positive, 40 (18.9%) were anti-HBs positive. At 1 month after a single-dose booster for anti-HBs-negative students, 14.5% had anti-HBs <10 mIU/mL, 29.0% and 56.5% were 10-100 and >100 mIU/mL, respectively. The anti-HBs levels were significantly higher for females than males (mean [SD]: 431 [418] vs. 246 [339] mIU/mL, P = 0.047). At 2-4 month after the third booster dose, 97.1% had anti-HBs >100 mIU/mL and 2.9% had 10-100 mIU/mL. Pre-booster check is still worthwhile to identify carriers among newly recruited healthcare workers born after adoption of neonatal immunization. A 3-dose booster, rather than a single dose, is required for the majority to achieve an anti-HBs level >100 mIU/mL, as memory immunity has declined in a substantial proportion of individuals. Cost-effectiveness of post-booster check for anti-HBs is low and should be further evaluated based on contextual specific utilization of results.

  6. InSight Atlas V Booster Transport

    NASA Image and Video Library

    2018-03-02

    A United Launch Alliance Atlas V booster arrives at Space Launch Complex 3 at Vandenberg Air Force Base in California. The rocket will be positioned on the pad to launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

  7. NASA's Space Launch System Advanced Booster Engineering Demonstration and/or Risk Reduction Efforts

    NASA Technical Reports Server (NTRS)

    Crumbly, Christopher M.; Dumbacher, Daniel L.; May, Todd A.

    2012-01-01

    The National Aeronautics and Space Administration (NASA) formally initiated the Space Launch System (SLS) development in September 2011, with the approval of the program s acquisition plan, which engages the current workforce and infrastructure to deliver an initial 70 metric ton (t) SLS capability in 2017, while using planned block upgrades to evolve to a full 130 t capability after 2021. A key component of the acquisition plan is a three-phased approach for the first stage boosters. The first phase is to complete the development of the Ares and Space Shuttle heritage 5-segment solid rocket boosters (SRBs) for initial exploration missions in 2017 and 2021. The second phase in the booster acquisition plan is the Advanced Booster Risk Reduction and/or Engineering Demonstration NASA Research Announcement (NRA), which was recently awarded after a full and open competition. The NRA was released to industry on February 9, 2012, with a stated intent to reduce risks leading to an affordable advanced booster and to enable competition. The third and final phase will be a full and open competition for Design, Development, Test, and Evaluation (DDT&E) of the advanced boosters. There are no existing boosters that can meet the performance requirements for the 130 t class SLS. The expected thrust class of the advanced boosters is potentially double the current 5-segment solid rocket booster capability. These new boosters will enable the flexible path approach to space exploration beyond Earth orbit (BEO), opening up vast opportunities including near-Earth asteroids, Lagrange Points, and Mars. This evolved capability offers large volume for science missions and payloads, will be modular and flexible, and will be right-sized for mission requirements. NASA developed the Advanced Booster Engineering Demonstration and/or Risk Reduction NRA to seek industry participation in reducing risks leading to an affordable advanced booster that meets the SLS performance requirements

  8. Closeup view of the Solid Rocket Booster (SRB) Frustum mounted ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster (SRB) Frustum mounted on ground support equipment in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center as it is being prepared to be mated with the Nose Cap and Forward Skirt. The Frustum contains the three Main Parachutes, Altitude Switches and forward booster Separation Motors. The Separation Motors burn for one second to ensure the SRBs drift away from the External Tank and Orbiter at separation. The three main parachutes are deployed to reduce speed as the SRBs descend to a splashdown in the Atlantic Ocean where they are recovered refurbished and reused. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  9. Closeup view of the Solid Rocket Booster (SRB) Forward Skirt, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster (SRB) Forward Skirt, Frustum and Nose Cap mated assembly undergoing final preparations in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center. In this view the access panel on the Forward Skirt is removed and you can see a small portion of the interior of the Forward Skirt. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  10. The StarBooster System: A Cargo Aircraft for Space

    NASA Technical Reports Server (NTRS)

    Davis, Hubert P.; Dula, Arthur M.; McLaughlin, Don; Frassanito, John; Andrews, Jason (Editor)

    1999-01-01

    Starcraft Boosters has developed a different approach for lowering the cost of access to space. We propose developing a new aircraft that will house an existing expendable rocket stage. This vehicle, termed StarBooster, will be the first stage of a family of launch vehicles. By combining these elements, we believe we can reduce the cost and risk of fielding a new partially reusable launch system. This report summarizes the work performed on the StarBooster concept since the company's inception in 1996. Detailed analyses are on-going and future reports will focus on the maturation of the vehicle and system design.

  11. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    One of two new work platforms for NASA's Space Launch System booster engines is secured on dunnage inside the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  12. A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording.

    PubMed

    Crescentini, Marco; Bennati, Marco; Saha, Shimul Chandra; Ivica, Josip; de Planque, Maurits; Morgan, Hywel; Tartagni, Marco

    2016-05-19

    High-throughput screening (HTS) using ion channel recording is a powerful drug discovery technique in pharmacology. Ion channel recording with planar bilayer lipid membranes (BLM) is scalable and has very high sensitivity. A HTS system based on BLM ion channel recording faces three main challenges: (i) design of scalable microfluidic devices; (ii) design of compact ultra-low-noise transimpedance amplifiers able to detect currents in the pA range with bandwidth >10 kHz; (iii) design of compact, robust and scalable systems that integrate these two elements. This paper presents a low-noise transimpedance amplifier with integrated A/D conversion realized in CMOS 0.35 μm technology. The CMOS amplifier acquires currents in the range ±200 pA and ±20 nA, with 100 kHz bandwidth while dissipating 41 mW. An integrated digital offset compensation loop balances any voltage offsets from Ag/AgCl electrodes. The measured open-input input-referred noise current is as low as 4 fA/√Hz at ±200 pA range. The current amplifier is embedded in an integrated platform, together with a microfluidic device, for current recording from ion channels. Gramicidin-A, α-haemolysin and KcsA potassium channels have been used to prove both the platform and the current-to-digital converter.

  13. A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording

    PubMed Central

    Crescentini, Marco; Bennati, Marco; Saha, Shimul Chandra; Ivica, Josip; de Planque, Maurits; Morgan, Hywel; Tartagni, Marco

    2016-01-01

    High-throughput screening (HTS) using ion channel recording is a powerful drug discovery technique in pharmacology. Ion channel recording with planar bilayer lipid membranes (BLM) is scalable and has very high sensitivity. A HTS system based on BLM ion channel recording faces three main challenges: (i) design of scalable microfluidic devices; (ii) design of compact ultra-low-noise transimpedance amplifiers able to detect currents in the pA range with bandwidth >10 kHz; (iii) design of compact, robust and scalable systems that integrate these two elements. This paper presents a low-noise transimpedance amplifier with integrated A/D conversion realized in CMOS 0.35 μm technology. The CMOS amplifier acquires currents in the range ±200 pA and ±20 nA, with 100 kHz bandwidth while dissipating 41 mW. An integrated digital offset compensation loop balances any voltage offsets from Ag/AgCl electrodes. The measured open-input input-referred noise current is as low as 4 fA/√Hz at ±200 pA range. The current amplifier is embedded in an integrated platform, together with a microfluidic device, for current recording from ion channels. Gramicidin-A, α-haemolysin and KcsA potassium channels have been used to prove both the platform and the current-to-digital converter. PMID:27213382

  14. PULSE AMPLIFIER

    DOEpatents

    Johnstone, C.W.

    1958-06-17

    The improvement of pulse amplifiers used with scintillation detectors is described. The pulse amplifier circuit has the advantage of reducing the harmful effects of overloading cause by large signal inputs. In general the pulse amplifier circuit comprises two amplifier tubes with the input pulses applied to one amplifier grid and coupled to the second amplifier tube through a common cathode load. The output of the second amplifier is coupled from the plate circuit to a cathode follower tube grid and a diode tube in connected from grid to cathode of the cathode follower tube. Degenerative feedback is provided in the second amplifier by coupling a signal from the cathode follower cathode to the second amplifier grid. The circuit proqides moderate gain stability, and overload protection for subsequent pulse circuits.

  15. Lessons Learned for Follow-up Phone Booster Counseling Calls with Substance Abusing Emergency Department Patients

    PubMed Central

    Donovan, Dennis M.; Hatch-Maillette, Mary A.; Phares, Melissa M.; McGarry, Ernest; Peavy, K. Michelle; Taborsky, Julie

    2014-01-01

    Background Post-visit “booster” sessions have been recommended to augment the impact of brief interventions delivered in the Emergency Department (ED). This paper, which focuses on implementation issues, presents descriptive information and interventionists’ qualitative perspectives on providing brief interventions over the phone, challenges, “lessons learned”, and recommendations for others attempting to implement adjunctive booster calls. Method Attempts were made to complete two 20-minute telephone “booster” calls within a week following a patient’s ED discharge with 425 patients who screened positive for and had recent problematic substance use other than alcohol or nicotine. Results Over half (56.2%) of participants completed the initial call; 66.9% of those who received the initial call also completed the second call. Median number of attempts to successfully contact participants for the first and second calls was 4 and 3, respectively. Each completed call lasted an average of about 22 minutes. Common challenges/barriers identified by booster callers included unstable housing, limited phone access, unavailability due to additional treatment, lack of compensation for booster calls, and booster calls coming from an area code different than the participants’ locale and from someone other than ED staff. Conclusions Specific recommendations are presented with respect to implementing a successful centralized adjunctive booster call system. Future use of booster calls might be informed by research on contingency management (e.g., incentivizing call completions), smoking cessation quitlines, and phone-based continuing care for substance abuse patients. Future research needs to evaluate the incremental benefit of adjunctive booster calls on outcomes over and above that of brief motivational interventions delivered in the ED setting. PMID:25534151

  16. High-power microwave amplifier based on overcritical relativistic electron beam without external magnetic field

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kurkin, S. A., E-mail: KurkinSA@gmail.com; Koronovskii, A. A.; Saratov State Technical University, Politechnicheskaja 77, Saratov 410028

    2015-04-13

    The high-power scheme for the amplification of powerful microwave signals based on the overcritical electron beam with a virtual cathode (virtual cathode amplifier) has been proposed and investigated numerically. General output characteristics of the virtual cathode amplifier including the dependencies of the power gain on the input signal frequency and amplitude have been obtained and analyzed. The possibility of the geometrical working frequency tuning over the range about 8%–10% has been shown. The obtained results demonstrate that the proposed virtual cathode amplifier scheme may be considered as the perspective high-power microwave amplifier with gain up to 18 dB, and with themore » following important advantages: the absence of external magnetic field, the simplicity of construction, the possibility of geometrical frequency tuning, and the amplification of relatively powerful microwave signals.« less

  17. Do parental decision-making patterns predict compliance with use of child booster seats?

    PubMed

    Shimony-Kanat, Sarit; Gofin, Rosa; Kienski Woloski Wruble, Anna C; Mann, Leon

    2018-03-01

    Booster seat use for 4-9 year olds remains the lowest of all age groups in many countries. The objective of this study is to examine whether parents' decision-making patterns, as measured by the Melbourne Decision Making Questionnaire, relate to car booster seat use. Israeli parents of 4-7 years old children (n = 398) answered a questionnaire about car safety and decision-making habits. Ninety per cent of parents reported having a booster seat; 70.5% reported consistent booster seat use in general and on short drives during the last month (booster seat use compliance index). Greater compliance index was positively related to a vigilant decision-making pattern, passenger compliance with rear seat belts and families with fewer children. Lower booster seat use compliance index was associated with buck-passing decision-making pattern. Health professionals and policy-makers should take into account parents' habitual decision-making patterns when designing interventions for car booster seat compliance.

  18. Space transportation booster engine configuration study. Volume 1: Executive Summary

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The objective of the Space Transportation Booster Engine (STBE) Configuration Study is to contribute to the Advanced Launch System (ALS) development effort by providing highly reliable, low cost booster engine concepts for both expendable and reusable rocket engines. The objectives of the Space Transportation Booster Engine (STBE) Configuration Study were to identify engine configurations which enhance vehicle performance and provide operational flexibility at low cost, and to explore innovative approaches to the follow-on full-scale development (FSD) phase for the STBE.

  19. Update on Risk Reduction Activities for a Liquid Advanced Booster for NASA's Space Launch System

    NASA Technical Reports Server (NTRS)

    Crocker, Andy; Greene, William D.

    2017-01-01

    Goals of NASA's Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) are to: (1) Reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS. (2) Enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. SLS Block 1 vehicle is being designed to carry 70 mT to LEO: (1) Uses two five-segment solid rocket boosters (SRBs) similar to the boosters that helped power the space shuttle to orbit. Evolved 130 mT payload class rocket requires an advanced booster with more thrust than any existing U.S. liquid-or solid-fueled boosters

  20. Gain-clamped semiconductor optical amplifiers based on compensating light: Theoretical model and performance analysis

    NASA Astrophysics Data System (ADS)

    Jia, Xin-Hong; Wu, Zheng-Mao; Xia, Guang-Qiong

    2006-12-01

    It is well known that the gain-clamped semiconductor optical amplifier (GC-SOA) based on lasing effect is subject to transmission rate restriction because of relaxation oscillation. The GC-SOA based on compensating effect between signal light and amplified spontaneous emission by combined SOA and fiber Bragg grating (FBG) can be used to overcome this problem. In this paper, the theoretical model on GC-SOA based on compensating light has been constructed. The numerical simulations demonstrate that good gain and noise figure characteristics can be realized by selecting reasonably the FBG insertion position, the peak reflectivity of FBG and the biasing current of GC-SOA.

  1. Aerodynamic characterisation and trajectory simulations for the Ariane-5 booster recovery system

    NASA Astrophysics Data System (ADS)

    Meiboom, F. P.

    One of the most critical aspects of the early phases of the development of the Ariane-5 booster recovery system was the determination of the behavior of the booster during its atmospheric reentry, since this behavior determines the start conditions for the parachute system elements. A combination of wind-tunnel tests (subsonic and supersonic) and analytical methods was applied to define the aerodynamic characteristics of the booster. This aerodynamic characterization in combination with information of the ascent trajectory, atmospheric properties and booster mass and inertia were used as input for the 6-DOF trajectory simulations of the vehicle. Uncertainties in aerodynamic properties and deviations in atmospheric and booster properties were incorporated to define the range of initial conditions for the parachute system, utilizing stochastic (Monte-Carlo) methods.

  2. Ram booster

    NASA Technical Reports Server (NTRS)

    Brand, Vance D. (Inventor); Morgan, Walter Ray (Inventor)

    2011-01-01

    The present invention is a space launch system and method to propel a payload bearing craft into earth orbit. The invention has two, or preferably, three stages. The upper stage has rocket engines capable of carrying a payload to orbit and provides the capability of releasably attaching to the lower, or preferably, middle stage. Similar to the lower stage, the middle stage is a reusable booster stage that employs all air breathing engines, is recoverable, and can be turned-around in a short time between missions.

  3. Combating pertussis resurgence: One booster vaccination schedule does not fit all.

    PubMed

    Riolo, Maria A; Rohani, Pejman

    2015-02-03

    Pertussis has reemerged as a major public health concern in many countries where it was once considered well controlled. Although the mechanisms responsible for continued pertussis circulation and resurgence remain elusive and contentious, many countries have nevertheless recommended booster vaccinations, the timing and number of which vary widely. Here, using a stochastic, age-stratified transmission model, we searched for cost-effective booster vaccination strategies using a genetic algorithm. We did so assuming four hypothesized mechanisms underpinning contemporary pertussis epidemiology: (I) insufficient coverage, (II) frequent primary vaccine failure, (III) waning of vaccine-derived protection, and (IV) vaccine "leakiness." For scenarios I-IV, successful booster strategies were identified and varied considerably by mechanism. Especially notable is the inability of booster schedules to alleviate resurgence when vaccines are leaky. Critically, our findings argue that the ultimate effectiveness of vaccine booster schedules will likely depend on correctly pinpointing the causes of resurgence, with misdiagnosis of the problem epidemiologically ineffective and economically costly.

  4. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines nears the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be delivered to the VAB, where they will be stored and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  5. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines backs up inside the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  6. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines backs in to the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  7. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines arrives inside the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  8. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines arrives at the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  9. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    New service platforms for NASA's Space Launch System booster engines, secured on two flatbed trucks, are on their way to the agency's Kennedy Space Center in Florida. They are being transported from fabricator Met-Con Inc. in Cocoa, Florida. The platforms will be delivered to the Vehicle Assembly Building, where they will be stored and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  10. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines makes its way along the NASA Causeway to the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be delivered to the Vehicle Assembly Building, where they will be stored and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  11. Segmented amplifier configurations for laser amplifier

    DOEpatents

    Hagen, Wilhelm F.

    1979-01-01

    An amplifier system for high power lasers, the system comprising a compact array of segments which (1) preserves high, large signal gain with improved pumping efficiency and (2) allows the total amplifier length to be shortened by as much as one order of magnitude. The system uses a three dimensional array of segments, with the plane of each segment being oriented at substantially the amplifier medium Brewster angle relative to the incident laser beam and with one or more linear arrays of flashlamps positioned between adjacent rows of amplifier segments, with the plane of the linear array of flashlamps being substantially parallel to the beam propagation direction.

  12. Fast optimization of multipump Raman amplifiers based on a simplified wavelength and power budget heuristic

    NASA Astrophysics Data System (ADS)

    de O. Rocha, Helder R.; Castellani, Carlos E. S.; Silva, Jair A. L.; Pontes, Maria J.; Segatto, Marcelo E. V.

    2015-01-01

    We report a simple budget heuristic for a fast optimization of multipump Raman amplifiers based on the reallocation of the pump wavelengths and the optical powers. A set of different optical fibers are analyzed as the Raman gain medium, and a four-pump amplifier setup is optimized for each of them in order to achieve ripples close to 1 dB and gains up to 20 dB in the C band. Later, a comparison between our proposed heuristic and a multiobjective optimization based on a nondominated sorting genetic algorithm is made, highlighting the fact that our new approach can give similar solutions after at least an order of magnitude fewer iterations. The results shown in this paper can potentially pave the way for real-time optimization of multipump Raman amplifier systems.

  13. 13. VIEW OF BOOSTER STATION 4 CHLORINATOR INTERIOR, FACING NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. VIEW OF BOOSTER STATION 4 CHLORINATOR INTERIOR, FACING NORTH - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  14. 39. VIEW OF CHRYSLER WORKERS LOADING A SATURN IB BOOSTER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. VIEW OF CHRYSLER WORKERS LOADING A SATURN IB BOOSTER INTO THE EAST POSITION ON THE STATIC TEST TOWER. AS THE MAIN CONTRACTOR OF THE SATURN IB BOOSTER, CHRYSLER TOOK OVER OPERATIONS OF THE EAST POSITION OF THE STATIC TEST TOWER IN 1963. THAT SAME YEAR, THE WEST POSITION OF THE TEST TOWER WAS MODIFIED (AS SEEN IN THE PHOTO) FOR RESEARCH AND DEVELOPMENT TESTS OF THE SATURN V BOOSTER'S ENGINE, THE F-1. MARCH 1963, MSFC PHOTO LAB. - Marshall Space Flight Center, Saturn Propulsion & Structural Test Facility, East Test Area, Huntsville, Madison County, AL

  15. Closeup view of the Solid Rocket Booster (SRB) Forward Skirt, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster (SRB) Forward Skirt, Frustum and Nose Cap mated assembly undergoing final preparations in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center. The prominent feature in this view is the Forward Thrust Attach Fitting which mates up with the Forward Thrust Attach Fitting of the External Tank (ET) at the ends of the SRB Beam that runs through the ET's Inter Tank Assembly. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  16. Closeup view of the Solid Rocket Booster (SRB) Nose Caps ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster (SRB) Nose Caps mounted on ground support equipment in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center as they are being prepared for attachment to the SRB Frustum. The Nose Cap contains the Pilot and Drogue Chutes that are deployed prior to the main chutes as the SRBs descend to a splashdown in the Atlantic Ocean where they are recovered refurbished and reused. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  17. Booster dose vaccination for preventing hepatitis B.

    PubMed

    Poorolajal, Jalal; Hooshmand, Elham

    2016-06-07

    Antibodies against hepatitis B surface antigen (HBsAg) wane over time following hepatitis B immunisation; hence, it is unclear whether people vaccinated in three-dose or four-dose schedules of the hepatitis B vaccine are still immune when the hepatitis B surface antibody (anti-HBs) level in their body is undetectable, or lower than the level usually considered protective. This question may potentially be answered indirectly by measuring the anamnestic immune response to a booster dose of vaccine. The term 'booster' (or revaccination) refers to an additional dose of hepatitis B vaccine (HBV) given some time post-primary vaccination to induce immune memory and improve protection against hepatitis B virus (HBV) infection. To assess the benefits and harms of booster dose hepatitis B vaccination, more than five years after the primary vaccination, for preventing HBV infection in healthy individuals previously vaccinated with the hepatitis B vaccine, and with hepatitis B surface antibody (anti-HBs) levels below 10 mIU/mL. We searched the Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, Science Citation Index Expanded, conference databases, and reference lists of articles to January 2016. We also contacted authors of articles. In addition, we searched ClinicalTrials.gov and the World Health Organization (WHO) International Clinical Trials Registry Platform for ongoing trials (May 2016). Randomised clinical trials addressing anamnestic immune response to a booster dose of hepatitis B vaccine, more than five years after the primary vaccination, in apparently healthy participants, vaccinated in a three-dose or four-dose schedule of the hepatitis B vaccine during the primary vaccination, without receiving an additional dose or immunoglobulin. Both review authors decided if the identified studies met the inclusion criteria or not. Primary outcomes included the proportion of participants

  18. A small signal amplifier based on ionic liquid gated black phosphorous field effect transistor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Das, Saptarshi; Zhang, Wei; Thoutam, Laxman Raju

    2015-04-10

    In this article we report an analog small signal amplifier based on semiconducting black phosphorus (BP), the most recent addition to the family of two dimensional crystals. The amplifier, consisting of a BP load resistor and a BP field effect transistor (FET) was integrated on a single flake. The gain of the amplifier was found to be ~9 and it remained undistorted for input signal frequencies up to 15 kHz. In addition, we also report record high ON current of 200 µA/µm at V DD = -0.5V in BP FETs. Our results demonstrates the possibility for the implementation of BPmore » in the future generations of analog devices.« less

  19. Fiber Based Optical Amplifier for High Energy Laser Pulses Final Report CRADA No. TC02100.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Messerly, M.; Cunningham, P.

    This was a collaborative effort between Lawrence Livermore National Security, LLC (formerly The Regents of the University of California)/Lawrence Livermore National Laboratory (LLNL), and The Boeing Company to develop an optical fiber-based laser amplifier capable of producing and sustaining very high-energy, nanosecond-scale optical pulses. The overall technical objective of this CRADA was to research, design, and develop an optical fiber-based amplifier that would meet specific metrics.

  20. STABILIZED TRANSISTOR AMPLIFIER

    DOEpatents

    Noe, J.B.

    1963-05-01

    A temperature stabilized transistor amplifier having a pair of transistors coupled in cascade relation that are capable of providing amplification through a temperature range of - 100 un. Concent 85% F to 400 un. Concent 85% F described. The stabilization of the amplifier is attained by coupling a feedback signal taken from the emitter of second transistor at a junction between two serially arranged biasing resistances in the circuit of the emitter of the second transistor to the base of the first transistor. Thus, a change in the emitter current of the second transistor is automatically corrected by the feedback adjustment of the base-emitter potential of the first transistor and by a corresponding change in the base-emitter potential of the second transistor. (AEC)

  1. Identifying strategies to improve the effectiveness of booster seat laws

    DOT National Transportation Integrated Search

    2008-05-01

    The objective of this project was to identify strategies to improve the effectiveness of booster seat laws. The project explored the possible factors that relate to the use and nonuse of booster seats, and examined the attitudes of law enforcement of...

  2. Study of solid rocket motors for a space shuttle booster. Appendix D: Recovery and reuse 156-inch diameter solid rocket motor booster

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The baseline for a space shuttle configuration utilizing two parallel-burn, 156-in.-diameter SRMs with three segments and techroll seal movable nozzles is presented. The concept and general economic benefits of SRM recovery are equally valid for the series-burn SRMs, provided that those SRMs are also designed for the same strength, stiffness, segmentation, and interchangeability as the present design, and that those SRMs are also recovered as individual units. Feasibility studies were initiated to investigate SRM recoverability. These studies were based upon recovery of the SRM boosters for the Titan 3C. Ground rules precluded SRM modification that required significant changes in motor qualification or schedule. Even with this restriction, the study determined that the recoverable booster concept was completely feasible, both technically and economically. Parachute recovery has been selected as the best method, principally because it can accomplish the task with a minimum development cost and time to achieve operational recovery status. This system affords the highest probability for achieving large cost reductions.

  3. Dual Liquid Flyback Booster for the Space Shuttle

    NASA Technical Reports Server (NTRS)

    Blum, C.; Jones, P.; Meinders, B.

    1998-01-01

    Liquid Flyback Boosters provide an opportunity to improve shuttle safety, increase performance, and reduce operating costs. The objective of the LFBB study is to establish the viability of a LFBB configuration to integrate into the shuffle vehicle and meet the goals of the Space Shuttle upgrades program. The design of a technically viable LFBB must integrate into the shuffle vehicle with acceptable impacts to the vehicle elements, i.e. orbiter and external tank and the shuttle operations infrastructure. The LFBB must also be capable of autonomous return to the launch site. The smooth integration of the LFBB into the space shuttle vehicle and the ability of the LFBB to fly back to the launch site are not mutually compatible capabilities. LFBB wing configurations optimized for ascent must also provide flight quality during the powered return back to the launch site. This paper will focus on the core booster design and ascent performance. A companion paper 'Conceptual Design for a Space Shuttle Liquid Flyback Booster' will focus on the flyback system design and performance. The LFBB study developed design and aerodynamic data to demonstrate the viability of a dual booster configuration to meet the shuttle upgrade goals, i.e. enhanced safety, improved performance and reduced operations costs.

  4. Dual Liquid Flyback Booster for the Space Shuttle

    NASA Technical Reports Server (NTRS)

    Blum, C.; Jones, Patti; Meinders, B.

    1998-01-01

    Liquid Flyback Boosters provide an opportunity to improve shuttle safety, increase performance, and reduce operating costs. The objective of the LFBB study is to establish the viability of a LFBB configuration to integrate into the shuttle vehicle and meet the goals of the Space Shuttle upgrades program. The design of a technically viable LFBB must integrate into the shuttle vehicle with acceptable impacts to the vehicle elements, i.e. orbiter and external tank and the shuttle operations infrastructure. The LFBB must also be capable of autonomous return to the launch site. The smooth integration of the LFBB into the space shuttle vehicle and the ability of the LFBB to fly back to the launch site are not mutually compatible capabilities. LFBB wing configurations optimized for ascent must also provide flight quality during the powered return back to the launch site. This paper will focus on the core booster design and ascent performance. A companion paper, "Conceptual Design for a Space Shuttle Liquid Flyback Booster" will focus on the flyback system design and performance. The LFBB study developed design and aerodynamic data to demonstrate the viability of a dual booster configuration to meet the shuttle upgrade goals, i.e. enhanced safety, improved performance and reduced operations costs.

  5. Space Launch System NASA Research Announcement Advanced Booster Engineering Demonstration and/or Risk Reduction

    NASA Technical Reports Server (NTRS)

    Crumbly, Christopher M.; Craig, Kellie D.

    2011-01-01

    The intent of the Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) effort is to: (1) Reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS (2) Enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. Key Concepts (1) Offerors must propose an Advanced Booster concept that meets SLS Program requirements (2) Engineering Demonstration and/or Risk Reduction must relate to the Offeror s Advanced Booster concept (3) NASA Research Announcement (NRA) will not be prescriptive in defining Engineering Demonstration and/or Risk Reduction

  6. Initiation Capacity of a Specially Shaped Booster Pellet and Numerical Simulation of Its Initiation Process

    NASA Astrophysics Data System (ADS)

    Hu, Li-Shuang; Hu, Shuang-Qi; Cao, Xiong; Zhang, Jian-Ren

    2014-01-01

    The insensitive main charge explosive is creating new requirements for the booster pellet of detonation trains. The traditional cylindrical booster pellet has insufficient energy output to reliably initiate the insensitive main charge explosive. In this research, a concave spherical booster pellet was designed. The initiation capacity of the concave spherical booster pellet was studied using varied composition and axial steel dent methods. The initiation process of the concave spherical booster pellet was also simulated by ANSYS/LS-DYNA. The results showed that using a concave spherical booster allows a 42% reduction in the amount of explosive needed to match the initiation capacity of a conventional cylindrical booster of the same dimensions. With the other parameters kept constant, the initiation capacity of the concave spherical booster pellet increases with decreased cone angle and concave radius. The numerical simulation results are in good agreement with the experimental data.

  7. General view of a fully assembled Solid Rocket Booster sitting ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of a fully assembled Solid Rocket Booster sitting atop the Mobile Launch Platform in the Vehicle Assembly Building at Kennedy Space Center - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  8. Booster and higher antigen doses of inactivated influenza vaccine in HIV-infected patients.

    PubMed

    Johnston, Jessica A; Tincher, Lindsey B; Lowe, Denise K

    2013-12-01

    To review the literature regarding booster or higher doses of influenza antigen for increasing immunogenicity of inactivated influenza vaccine (IIV) in HIV-infected patients. MEDLINE (1966 to September 2013) was searched using the terms immunize, influenza, vaccine, and HIV or AIDS in combination with two-dose, booster-dose, increased antigen, or high-dose. One trial of booster dosing with standard doses (SDs) of IIV, trivalent (IIV3); 2 trials of booster dosing with intermediate doses (ID) of H1N1 IIV or IIV3; and 1 trial of high-dose (HD) IIV3 were identified. Trials administering 2-dose, booster-dose, or increased antigen of influenza vaccine to patients with HIV were reviewed. Because adjuvanted IIV is not available and IIV, quadrivalent was recently approved in the United States, studies evaluating these vaccines were excluded. HIV-infected individuals are at high risk for influenza-related complications; however, vaccination with SD IIV may not confer optimal protection. It has been postulated that booster or higher doses of influenza antigen may lead to increased immunogenicity. When ID and SD or ID with boosters were evaluated in HIV-infected patients, significant increases in surrogate markers for influenza protection were not achieved. However, HD IIV3 did result in significant increases in seroprotective antibody levels, though 'clinical' influenza was not evaluated. Currently, evidence is insufficient to reach conclusions about the efficacy of booster dosing, ID, or HD influenza vaccine in HIV-infected patients. Trials evaluating booster or higher-antigen doses of IIV for 'clinical' influenza are necessary before routinely recommending for HIV-infected patients.

  9. Closeup view of the Solid Rocket Booster (SRB) Frustum mounted ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster (SRB) Frustum mounted on ground support equipment in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center as it is being prepared to be mated with the Nose Cap and Forward Skirt. The Frustum contains the three Main Parachutes, Altitude Switches and forward booster Separation Motors. The Separation Motors burn for one second to ensure the SRBs drift away from the External Tank and Orbiter at separation. The three main parachutes are deployed to reduce speed as the SRBs descend to a splashdown in the Atlantic Ocean where they are recovered refurbished and reused. In this view the assembly is rotated so that the four Separation Motors are in view and aligned with the approximate centerline of the image. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  10. Exercise, manual therapy, and use of booster sessions in physical therapy for knee osteoarthritis: a multi-center, factorial randomized clinical trial.

    PubMed

    Fitzgerald, G K; Fritz, J M; Childs, J D; Brennan, G P; Talisa, V; Gil, A B; Neilson, B D; Abbott, J H

    2016-08-01

    (1) Do treatment effects differ between participants receiving manual therapy (MT) with exercise compared to subjects who don't, (2) are treatment effects sustained better when participants receive booster sessions compared to those who don't over a one year period in subjects with knee osteoarthritis (KOA)? Multi-center, 2 × 2 factorial randomized clinical trial. 300 participants with knee OA were randomized to four groups: exercise-no boosters (Ex), exercise-with boosters (Ex+B), manual therapy+exercise-no boosters (MT+Ex), manual therapy+exercise-with boosters (MT+Ex+B). The primary outcome was the Western Ontario and McMaster osteoarthritis index (WOMAC) at 1 year. Secondary outcomes included knee pain, physical performance tests, and proportions of participants meeting treatment responder criteria. There were no differences between groups on the WOMAC at 1 year or on any performance-based measures. Secondary analyses indicated a) better scores on the WOMAC and greater odds of being a treatment responder at 9 weeks for participants receiving MT, b) greater odds of being a treatment responder at 1 year for participants receiving boosters. Exploratory interaction analysis suggested knee pain decreases for participants receiving boosters and increases for participants not receiving boosters from 9 weeks to 1 year. MT or use of boosters with exercise did not result in additive improvement in the primary outcome at 1 year. Secondary outcomes suggest MT may have some short term benefit, and booster sessions may improve responder status and knee pain at 1 year. However, the role of booster sessions remains unclear in sustaining treatment effects and warrants further study. gov (NCT01314183). Copyright © 2016 Osteoarthritis Research Society International. All rights reserved.

  11. Closeup view of the Solid Rocket Booster (SRB) Forward Skirt ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster (SRB) Forward Skirt sitting on ground support equipment in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center while being prepared for mating with the Frustum-Nose Cap Assembly and the Forward Rocket Motor Segment. The prominent feature in this view is the electrical, data, telemetry and safety systems terminal which connects to the Aft Skirt Assembly systems via the Systems Tunnel that runs the length of the Rocket Motor. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  12. Engine protection system for recoverable rocket booster

    NASA Technical Reports Server (NTRS)

    Shelby, Jr., Jerry A. (Inventor)

    1994-01-01

    A rocket engine protection system for a recoverable rocket booster which is arranged to land in a salt water body in substantially a nose down attitude. The system includes an inflatable bag which is stowed on a portion of a flat annular rim of the aft skirt of the booster. The bag is hinged at opposing sides and is provided with springs that urge the bag open. The bag is latched in a stowed position during launch and prior to landing for recovery is unlatched to permit the bag to be urged open and into sealing engagement with the rim. A source of pressurized gas further inflates the bag and urges it into sealing engagement with the rim of the skirt where it is locked into position. The gas provides a positive pressure upon the interior of the bag to preclude entry of salt water into the skirt and into contact with the engine. A flotation arrangement may assist in precluding the skirt of the booster from becoming submerged.

  13. Hepatitis B vaccine booster dose: low-dose recombinant hepatitis B vaccines as a booster dose.

    PubMed

    Bryan, J P; MacArthy, P; Rudock, A; Fogarty, J P; Dowd, H; Legters, L J; Perine, P L

    1997-06-01

    The timing and best regimen for a booster dose of hepatitis B vaccine have not been determined. Two studies were conducted to determine the response to a booster dose of 5 micrograms recombinant hepatitis B vaccine. In the first study, a 5 micrograms (0.5 ml) dose of Recombivax HB was administered intramuscularly 38 months after the initial dose to 71 volunteers. In a second study, we offered a 5 micrograms dose recombinant hepatitis B vaccine, either Recombivax HB (0.5 ml) or Engerix B (0.25 ml), to students who had previously been immunized with three doses of vaccine. In the first study, among the 44 persons for whom postbooster sera were available, the geometric mean concentration of anti-hepatitis B surface antigens increased from 42 to 2090 mIU/ml after the 5 micrograms (0.5 ml) dose of Recombivax. In the second study, after a 5 micrograms (0.5 ml) dose of Recombivax, the geometric mean concentration increased from 43 to 990 mIU/ml (n = 48), and in the group that received a 5 micrograms (0.25 ml) dose of Engerix B, the concentration increased from 83 to 2337 mIU/ml (n = 45) (p = 0.18 for postdose concentrations). A 5 micrograms dose of recombinant vaccine results in an excellent booster response at a cost one fourth to one half that of a full 1 ml dose of vaccine.

  14. TDRS-M Atlas V Booster and Centaur Stages Arrival, Offload, and Transport (Booster) to ASOC

    NASA Image and Video Library

    2017-06-26

    The United Launch Alliance (ULA) Mariner arrives at Port Canaveral in Florida carrying an Atlas V rocket booster and centaur upper stage bounded for Cape Canaveral Air Force Station. The centaur upper stage is transported from the company's Mariner ship to the Delta Operations Center. The booster stage is transported to the Atlas Spaceflight Operations Center. The rocket is scheduled to launch the Tracking and Data Relay Satellite, TDRS-M. It will be the latest spacecraft destined for the agency's constellation of communications satellites that allows nearly continuous contact with orbiting spacecraft ranging from the International Space Station and Hubble Space Telescope to the array of scientific observatories. Liftoff atop the ULA Atlas V rocket is scheduled to take place from Cape Canaveral's Space Launch Complex 41 on Aug. 3, 2017 at 9:02 a.m. EDT.

  15. Optimal design and operation of booster chlorination stations layout in water distribution systems.

    PubMed

    Ohar, Ziv; Ostfeld, Avi

    2014-07-01

    This study describes a new methodology for the disinfection booster design, placement, and operation problem in water distribution systems. Disinfectant residuals, which are in most cases chlorine residuals, are assumed to be sufficient to prevent growth of pathogenic bacteria, yet low enough to avoid taste and odor problems. Commonly, large quantities of disinfectants are released at the sources outlets for preserving minimum residual disinfectant concentrations throughout the network. Such an approach can cause taste and odor problems near the disinfectant injection locations, but more important hazardous excessive disinfectant by-product formations (DBPs) at the far network ends, of which some may be carcinogenic. To cope with these deficiencies booster chlorination stations were suggested to be placed at the distribution system itself and not just at the sources, motivating considerable research in recent years on placement, design, and operation of booster chlorination stations in water distribution systems. The model formulated and solved herein is aimed at setting the required chlorination dose of the boosters for delivering water at acceptable residual chlorine and TTHM concentrations for minimizing the overall cost of booster placement, construction, and operation under extended period hydraulic simulation conditions through utilizing a multi-species approach. The developed methodology links a genetic algorithm with EPANET-MSX, and is demonstrated through base runs and sensitivity analyses on a network example application. Two approaches are suggested for dealing with water quality initial conditions and species periodicity: (1) repetitive cyclical simulation (RCS), and (2) cyclical constrained species (CCS). RCS was found to be more robust but with longer computational time. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines is being prepared for the move into the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platform was transported from fabricator Met-Con Inc. in Cocoa, Florida. It will be stored in the VAB, and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  17. Study of solid rocket motor for a space shuttle booster

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The study of solid rocket motors for a space shuttle booster was directed toward definition of a parallel-burn shuttle booster using two 156-in.-dia solid rocket motors. The study effort was organized into the following major task areas: system studies, preliminary design, program planning, and program costing.

  18. Space shuttle with common fuel tank for liquid rocket booster and main engines (supertanker space shuttle)

    NASA Technical Reports Server (NTRS)

    Thorpe, Douglas G.

    1991-01-01

    An operation and schedule enhancement is shown that replaces the four-body cluster (Space Shuttle Orbiter (SSO), external tank, and two solid rocket boosters) with a simpler two-body cluster (SSO and liquid rocket booster/external tank). At staging velocity, the booster unit (liquid-fueled booster engines and vehicle support structure) is jettisoned while the remaining SSO and supertank continues on to orbit. The simpler two-bodied cluster reduces the processing and stack time until SSO mate from 57 days (for the solid rocket booster) to 20 days (for the liquid rocket booster). The areas in which liquid booster systems are superior to solid rocket boosters are discussed. Alternative and future generation vehicles are reviewed to reveal greater performance and operations enhancements with more modifications to the current methods of propulsion design philosophy, e.g., combined cycle engines, and concentric propellant tanks.

  19. Identifying information that promotes belt-positioning booster use. Volume 2, Appendices

    DOT National Transportation Integrated Search

    2008-07-01

    Many parents with low educational attainment prematurely graduate their children to seat belt restraint rather than use belt-positioning booster seats. This study aimed to identify interventions that promoted booster seat use among this population. F...

  20. Liquid rocket booster study addendum

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Liquid rocket booster study (LRB) addendum to final report is presented in the form of the view-graphs. The following subject areas are covered: LRB launch vehicle concepts; LRB design; propulsion system configurations; LRB boattail for Shuttle-C application; and manned transportation systems.

  1. SQUARE WAVE AMPLIFIER

    DOEpatents

    Leavitt, M.A.; Lutz, I.C.

    1958-08-01

    An amplifier circuit is described for amplifying sigmals having an alternating current component superimposed upon a direct current component, without loss of any segnnent of the alternating current component. The general circuit arrangement includes a vibrator, two square wave amplifiers, and recombination means. The amplifier input is connected to the vibrating element of the vibrator and is thereby alternately applied to the input of each square wave amplifier. The detailed circuitry of the recombination means constitutes the novelty of the annplifier and consists of a separate, dual triode amplifier coupled to the output of each square wave amplifier with a recombination connection from the plate of one amplifier section to a grid of one section of the other amplifier. The recombination circuit has provisions for correcting distortion caused by overlapping of the two square wave voltages from the square wave amplifiers.

  2. An instrumentation amplifier based readout circuit for a dual element microbolometer infrared detector

    NASA Astrophysics Data System (ADS)

    de Waal, D. J.; Schoeman, J.

    2014-06-01

    The infrared band is widely used in many applications to solve problems stretching over very diverse fields, ranging from medical applications like inflammation detection to military, security and safety applications employing thermal imaging in low light conditions. At the heart of these optoelectrical systems lies a sensor used to detect incident infrared radiation, and in the case of this work our focus is on uncooled microbolometers as thermal detectors. Microbolometer based thermal detectors are limited in sensitivity by various parameters, including the detector layout and design, operating temperature, air pressure and biasing that causes self heating. Traditional microbolometers use the entire membrane surface for a single detector material. This work presents the design of a readout circuit amplifier where a dual detector element microbolometer is used, rather than the traditional single element. The concept to be investigated is based on the principle that both elements will be stimulated with a similar incoming IR signal and experience the same resistive change, thus creating a common mode signal. However, such a common mode signal will be rejected by a differential amplifier, thus one element is placed within a negative resistance converter to create a differential mode signal that is twice the magnitude of the comparable single mode signal of traditional detector designs. An instrumentation amplifier is used for the final stage of the readout amplifier circuit, as it allows for very high common mode rejection with proper trimming of the Wheatstone bridge to compensate for manufacturing tolerance. It was found that by implementing the above, improved sensitivity can be achieved.

  3. Does a booster intervention augment the preventive effects of an abbreviated version of the coping power program for aggressive children?

    PubMed

    Lochman, John E; Baden, Rachel E; Boxmeyer, Caroline L; Powell, Nicole P; Qu, Lixin; Salekin, Karen L; Windle, Michel

    2014-01-01

    Booster interventions have been presumed to be important methods for maintaining the effects of evidence-based programs for children with behavioral problems, but there has been remarkably little empirical attention to this assumption. The present study examines the effect of a child-oriented booster preventive intervention with children who had previously received an abbreviated version (24 child sessions, 10 parent sessions) of the Coping Power targeted prevention program. Two hundred and forty-one children (152 boys, 89 girls) were screened as having moderate to high levels of aggressive behavior in 4th grade, then half were randomly assigned to receive the abbreviated Coping Power program in 5th grade, and half of the preventive intervention children were then randomly assigned to a Booster condition in 6th grade. The Booster sessions consisted of brief monthly individual contacts, and were primarily with the children. Five assessments across 4 years were collected from teachers, providing a three-year follow-up for all children who participated in the project. Results indicated that the abbreviated Coping Power program (one-third shorter than the full intervention) had long-term effects in reducing children's externalizing problem behaviors, proactive and reactive aggression, impulsivity traits and callous-unemotional traits. The Booster intervention did not augment these prevention effects. These findings indicate that a briefer and more readily disseminated form of an evidence-based targeted preventive intervention was effective. The findings have potential implications for policy and guidelines about possible intervention length and booster interventions.

  4. Closeup view of the Solid Rocket Booster (SRB) Forward Skirt ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of the Solid Rocket Booster (SRB) Forward Skirt sitting on ground support equipment in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center while being prepared for mating with the Frustum-Nose Cap Assembly and the Forward Rocket Motor Segment. The prominent feature in this view is the Forward Thrust Attach Fitting which mates up with the Forward Thrust Attach Fitting of the External Tank (ET) at the ends of the SRB Beam that runs through the ET's Inter Tank Assembly. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  5. Mars Science Laboratory Atlas V First Stage Booster

    NASA Image and Video Library

    2011-09-07

    NASA Administrator Charles Bolden walks around the United Launch Alliance Atlas V first stage booster with United Launch Alliance Vice President of Mission operations Jim Sponnick, NASA Mission Manager for Launch Services Wanda Harding, NASA Senior Advisor Mike French, and White House Fellow Debra Kurshan, Wednesday, Sept. 7, 2011, at the Cape Canaveral Air Force Station in Cape Canaveral, Fla. The booster will help send NASA's Mars Science Laboratory Curiosity rover to Mars later this year. Photo Credit: (NASA/Bill Ingalls)

  6. Development of the beam extraction synchronization system at the Fermilab Booster

    NASA Astrophysics Data System (ADS)

    Seiya, K.; Chaurize, S.; Drennan, C. C.; Pellico, W.; Sullivan, T.; Triplett, A. K.; Waller, A. M.

    2015-11-01

    The new beam extraction synchronization control system called "Magnetic Cogging" was developed at the Fermilab Booster and it replaces a system called "RF Cogging" as part of the Proton Improvement Plan (PIP).[1] The flux throughput goal for the PIP is 2.2×1017 protons per hour, which is double the present flux. The flux increase will be accomplished by doubling the number of beam cycles which, in turn, will double the beam loss in the Booster accelerator if nothing else is done. The Booster accelerates beam from 400 MeV to 8 GeV and extracts it to the Main Injector (MI) or Recycler Ring (RR). Cogging controls the beam extraction gap position which is created early in the Booster cycle and synchronizes the gap to the rising edge of the Booster extraction kicker and the MI/RR injection kicker. The RF Cogging system controls the gap position by changing only the radial position of the beam thus limiting the beam aperture and creating beam loss due to beam scraping. The Magnetic Cogging system controls the gap position with the magnetic field of the dipole correctors while the radial position feedback keeps the beam on a central orbit. Also with Magnetic Cogging the gap creation can occur earlier in the Booster cycle when the removed particles are at a lower energy. Thus Magnetic Cogging reduces the deposited energy of the lost particles (beam energy loss) and results in less beam loss activation. Energy loss was reduced by 40% by moving the gap creation energy from 700 MeV to 400 MeV when the Booster Cogging system was switched from RF Cogging to Magnetic Cogging in March 2015.

  7. Did two booster doses for schoolchildren change the epidemiology of pertussis in Israel?

    PubMed

    Anis, Emilia; Moerman, Larisa; Ginsberg, Gary; Karakis, Isabella; Slater, Paul E; Warshavsky, Bruce; Gosinov, Ruslan; Grotto, Itamar; Marva, Esther

    2018-05-28

    Pertussis is the only vaccine-preventable disease that has re-emerged in Israel. In the last two decades, despite high primary immunization coverage, crude incidence increased over tenfold, with especially high morbidity among infants and adolescents and with 19 infant deaths. Two pertussis vaccine boosters were added, in 2005 for 7-year-olds and in 2011 for 13-year-olds. We reviewed age group incidence from 1999 to 2016, before and after the booster program introduction. We compared three groups of 13-15 year-olds with identical primary immunization but different booster immunization histories. Vaccine effectiveness was calculated before and after adjustment for specific incidence in those aged 65 and over. Two years after one booster, adjusted vaccine effectiveness was 74.5%. Two years after two boosters, adjusted vaccine effectiveness was 91.8%. However, crude morbidity rates were not reduced. The booster program has been effective only among recipient groups. The program will be continued. Israel is now encouraging pregnant women to be vaccinated against pertussis to improve protection of infants.

  8. Economics of the solid rocket booster for space shuttle

    NASA Technical Reports Server (NTRS)

    Rice, W. C.

    1979-01-01

    The paper examines economics of the solid rocket booster for the Space Shuttle. Costs have been held down by adapting existing technology to the 146 in. SRB selected, with NASA reducing the cost of expendables and reusing the expensive nonexpendable hardware. Drop tests of Titan III motor cases and nozzles proved that boosters can survive water impact at vertical velocities of 100 ft/sec so that SRB components can be reused. The cost of expendables was minimized by selecting proven propellants, insulation, and nozzle ablatives of known costs; the propellant has the lowest available cost formulation, and low cost ablatives, such as pitch carbon fibers, will be used when available. Thus, the use of proven technology and low cost expendables will make the SRB an economical booster for the Space Shuttle.

  9. Exercise, Manual Therapy, and Booster Sessions in Knee Osteoarthritis: Cost-Effectiveness Analysis From a Multicenter Randomized Controlled Trial.

    PubMed

    Bove, Allyn M; Smith, Kenneth J; Bise, Christopher G; Fritz, Julie M; Childs, John; Brennan, Gerard P; Abbott, J Haxby; Fitzgerald, G Kelley

    2018-01-01

    Limited information exists regarding the cost-effectiveness of rehabilitation strategies for individuals with knee osteoarthritis (OA). The study objective was to compare the cost-effectiveness of 4 different combinations of exercise, manual therapy, and booster sessions for individuals with knee OA. This economic evaluation involved a cost-effectiveness analysis performed alongside a multicenter randomized controlled trial. The study took place in Pittsburgh, Pennsylvania; Salt Lake City, Utah; and San Antonio, Texas. The study participants were 300 individuals taking part in a randomized controlled trial investigating various physical therapy strategies for knee OA. Participants were randomized into 4 treatment groups: exercise only (EX), exercise plus booster sessions (EX+B), exercise plus manual therapy (EX+MT), and exercise plus manual therapy and booster sessions (EX+MT+B). For the 2-year base case scenario, a Markov model was constructed using the United States societal perspective and a 3% discount rate for costs and quality-adjusted life years (QALYs). Incremental cost-effectiveness ratios were calculated to compare differences in cost per QALY gained among the 4 treatment strategies. In the 2-year analysis, booster strategies (EX+MT+B and EX+B) dominated no-booster strategies, with both lower health care costs and greater effectiveness. EX+MT+B had the lowest total health care costs. EX+B cost ${\\$}$1061 more and gained 0.082 more QALYs than EX+MT+B, for an incremental cost-effectiveness ratio of ${\\$}$12,900/QALY gained. The small number of total knee arthroplasty surgeries received by individuals in this study made the assessment of whether any particular strategy was more successful at delaying or preventing surgery in individuals with knee OA difficult. Spacing exercise-based physical therapy sessions over 12 months using periodic booster sessions was less costly and more effective over 2 years than strategies not containing booster sessions for

  10. [Results of Booster Vaccination in Children with Primary Vaccine Failure after Initial Varicella Vaccination].

    PubMed

    Ozakiv, Takao; Nishimura, Naoko; Gotoh, Kensei; Funahashi, Keiji; Yoshii, Hironori; Okuno, Yoshinobu

    2016-05-01

    In October 2014, the varicella vaccination policy in Japan was changed from a single voluntary inoculation to two routine inoculations. This paper reports the results of booster vaccination in children who did not show seroconversion after initial vaccination (i.e., primary vaccine failure : PVF) over a 7-year period prior to the introduction of routine varicella vaccination. Between November 2007 and May 2014, 273 healthy children aged between 1.1 and 14.5 years (median : 1.7 years) underwent varicella vaccination. Before and 4 to 6 weeks after vaccination, the antibody titers were measured using an immune adherence hemagglutination (IAHA) assay and a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). In addition, side reactions were examined during the four-week period after vaccination. Children who did not show IAHA seroconversion (PVF) were recommended to receive a booster vaccination, and the measurement of antibody titers and an assessment of side reactions were performed after the booster dose. In May 2015, a questionnaire was mailed to each of the 273 participants to investigate whether they had developed varicella and/or herpes zoster after vaccination. After initial vaccination, the IAHA seroconversion rate was 75% and the mean antibody titer (Log2) with seroconversion was 4.7, while the gpELISA seroconversion rate was 84% and the mean antibody titer (Log10) with seroconversion was 2.4. Among children with PVF, 54 received booster vaccination within 81 to 714 days (median : 139 days) after the initial vaccination. After booster vaccination, the IAHA seroconversion rate was 98% and the mean antibody titer (Log2) with seroconversion was 5.8. Both the seroconversion rate and the antibody titer were higher compared with the values after the initial vaccination (p < 0.01). After booster vaccination, the gpELISA seropositive rate was 100% and the mean positive antibody titer (Log 10) was 3.6 ; similar results were obtained for the IAHA assay, with

  11. Space shuttle: Aerodynamic heating tests of the MDAC delta wing orbiter and canard booster

    NASA Technical Reports Server (NTRS)

    Andresen, T. L.

    1972-01-01

    Design of an efficient thermal protection system for the space shuttle orbiter and booster is discussed, based on knowledge of the thermal environment to be experienced by the vehicles in all flight phases. The complex configurations of these vehicles limit the level of confidence which can be associated with purely analytical thermal environment predictions. Tests were conducted during April and May 1971 using an orbiter and booster model at a 96-in. hypersonic shock tunnel. Both models were tested separately as well as together. A sufficiently large range in Reynolds number was covered so that laminar, transitional, and turbulent data could be obtained.

  12. 47 CFR 74.1290 - FM translator and booster station information available on the Internet.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

  13. 47 CFR 74.780 - Broadcast regulations applicable to translators, low power, and booster stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., low power, and booster stations. 74.780 Section 74.780 Telecommunication FEDERAL COMMUNICATIONS... PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.780 Broadcast regulations applicable to translators, low power, and booster stations. The following rules are applicable to...

  14. 47 CFR 74.780 - Broadcast regulations applicable to translators, low power, and booster stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., low power, and booster stations. 74.780 Section 74.780 Telecommunication FEDERAL COMMUNICATIONS... PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.780 Broadcast regulations applicable to translators, low power, and booster stations. The following rules are applicable to...

  15. 47 CFR 74.1290 - FM translator and booster station information available on the Internet.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

  16. 47 CFR 74.1290 - FM translator and booster station information available on the Internet.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

  17. 47 CFR 74.780 - Broadcast regulations applicable to translators, low power, and booster stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., low power, and booster stations. 74.780 Section 74.780 Telecommunication FEDERAL COMMUNICATIONS... PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.780 Broadcast regulations applicable to translators, low power, and booster stations. The following rules are applicable to...

  18. LOGARITHMIC AMPLIFIER

    DOEpatents

    De Shong, J.A. Jr.

    1957-12-31

    A logarithmic current amplifier circuit having a high sensitivity and fast response is described. The inventor discovered the time constant of the input circuit of a system utilizing a feedback amplifier, ionization chamber, and a diode, is inversely proportional to the input current, and that the amplifier becomes unstable in amplifying signals in the upper frequency range when the amplifier's forward gain time constant equals the input circuit time constant. The described device incorporates impedance networks having low frequency response characteristic at various points in the circuit to change the forward gain of the amplifler at a rate of 0.7 of the gain magnitude for every two times increased in frequency. As a result of this improvement, the time constant of the input circuit is greatly reduced at high frequencies, and the amplifier response is increased.

  19. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines, secured on a flatbed truck, has arrived at the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. It was transported from fabricator Met-Con Inc. in Cocoa, Florida. The platform will be stored in the VAB and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1 (EM-1). During EM-1, an uncrewed Orion spacecraft will launch on the SLS to a stable orbit beyond the Moon and return to Earth for a splashdown in the Pacific Ocean.

  20. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines has been offloaded from a flatbed truck and is being prepared for the move into the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platform was transported from fabricator Met-Con Inc. in Cocoa, Florida. It will be stored in the VAB, and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  1. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines, secured on a flatbed truck, is on its way to the agency's Kennedy Space Center in Florida. It was transported from fabricator Met-Con Inc. in Cocoa, Florida. The platform will be delivered to the Vehicle Assembly Building, where it will be stored and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1 (EM-1). During EM-1, an uncrewed Orion spacecraft will launch on the SLS to a stable orbit beyond the Moon and return to Earth for a splashdown in the Pacific Ocean.

  2. Advanced Booster Composite Case/Polybenzimidazole Nitrile Butadiene Rubber Insulation Development

    NASA Technical Reports Server (NTRS)

    Gentz, Steve; Taylor, Robert; Nettles, Mindy

    2015-01-01

    The NASA Engineering and Safety Center (NESC) was requested to examine processing sensitivities (e.g., cure temperature control/variance, debonds, density variations) of polybenzimidazole nitrile butadiene rubber (PBI-NBR) insulation, case fiber, and resin systems and to evaluate nondestructive evaluation (NDE) and damage tolerance methods/models required to support human-rated composite motor cases. The proposed use of composite motor cases in Blocks IA and II was expected to increase performance capability through optimizing operating pressure and increasing propellant mass fraction. This assessment was to support the evaluation of risk reduction for large booster component development/fabrication, NDE of low mass-to-strength ratio material structures, and solid booster propellant formulation as requested in the Space Launch System NASA Research Announcement for Advanced Booster Engineering Demonstration and/or Risk Reduction. Composite case materials and high-energy propellants represent an enabling capability in the Agency's ability to provide affordable, high-performing advanced booster concepts. The NESC team was requested to provide an assessment of co- and multiple-cure processing of composite case and PBI-NBR insulation materials and evaluation of high-energy propellant formulations.

  3. Booster seat laws and child fatalities: a case-control study.

    PubMed

    Farmer, P; Howard, A; Rothman, L; Macpherson, A

    2009-10-01

    A case-control study examined, primarily, the association between booster seat laws and fatalities among children in frontal collisions and, secondarily, the association between booster seat laws and reported restraint use, and restraint use and child fatalities. Children who died in a crash in the US were cases, and children who survived a fatal crash were controls. Subjects were child passengers (4-8 years old) in the Fatality Analysis Reporting System Database, 1995-2005. In states with a booster seat law, children were less likely to die than in states without a law (OR 0.80; 95% CI 0.66 to 0.98). They were also more likely to be restrained (adjusted OR 1.59; 95% CI 1.21 to 2.09) and were more likely to be correctly restrained (adjusted OR 4.44; 95% CI 3.18 to 6.20). It is concluded that booster seat laws are associated with a decrease in child deaths and an increase in correct restraint use among children involved in a fatal crash in the USA.

  4. Study on the Structures of Two Booster Pellets Having High Initiation Capacity

    NASA Astrophysics Data System (ADS)

    Shuang-Qi, Hu; Hong-Rong, Liu; Li-shuang, Hu; Xiong, Cao; Xiang-Chao, Mi; Hai-Xia, Zhao

    2014-05-01

    Insensitive munitions (IM) improve the survivability of both weapons and their associated platforms, which can lead to a reduction in casualties, mission losses, and whole life costs. All weapon systems contain an explosive train that needs to meet IM criteria but reliably initiate a main charge explosive. To ensure that these diametrically opposed requirements can be achieved, new highly effective booster charge structures were designed. The initiation capacity of the two booster pellets was studied using varied composition and axial-steel-dent methods. The results showed that the two new booster pellets can initiate standard main charge pellets with less explosive mass than the ordinary cylindrical booster pellet. The numerical simulation results were in good agreement with the experiment results.

  5. Feasibility demonstration of booster cross-over system for 3 1/2 inch SRB/MLP frangible nut system

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Recent testing of the SRB/MLP Frangible Nut System (SOS Part Number 114850-9/Boosters P/N 114848-3) at NASA indicated a need to reduce the function time between boosters (2) within a single frangible nut. These boosters are initiated separately by electrical impulse(s). Coupling the output of each detonator with an explosive cross-over would reduce the function time between boosters (independent of electrical impulse) while providing additional redundancy to the system. The objectives of this program were to: provide an explosive cross-over between boosters, reduce function time between boosters to less than one (1) millisecond within a given nut, reduce cost of boosters, be compatible with the existing frangible nut system, and meet requirements of USBI Spec's (nut 10SPC-0030, booster 10SPC-0031).

  6. NASA's Space Launch System Booster Passes Major Milestone on Journey to Mars (QM-2)

    NASA Image and Video Library

    2016-06-28

    A booster for the most powerful rocket in the world, NASA’s Space Launch System (SLS), was fired up Tuesday, June 28 at 11:05 a.m. EDT for a second qualification ground test at Orbital ATK's test facilities in Promontory, Utah. This was the last full-scale test for the booster before SLS is ready in 2018 for the first uncrewed test flight with NASA’s Orion spacecraft, marking a key milestone on the agency’s Journey to Mars. The booster was tested at a cold motor conditioning target of 40 degrees Fahrenheit –the colder end of its accepted propellant temperature range. When ignited, temperatures inside the booster reached nearly 6,000 degrees. The two-minute, full-duration ground qualification test provided NASA with critical data on 82 qualification objectives that will support certification of the booster for flight. Engineers now will evaluate test data captured by more than 530 instrumentation channels on the booster.

  7. A study of two statistical methods as applied to shuttle solid rocket booster expenditures

    NASA Technical Reports Server (NTRS)

    Perlmutter, M.; Huang, Y.; Graves, M.

    1974-01-01

    The state probability technique and the Monte Carlo technique are applied to finding shuttle solid rocket booster expenditure statistics. For a given attrition rate per launch, the probable number of boosters needed for a given mission of 440 launches is calculated. Several cases are considered, including the elimination of the booster after a maximum of 20 consecutive launches. Also considered is the case where the booster is composed of replaceable components with independent attrition rates. A simple cost analysis is carried out to indicate the number of boosters to build initially, depending on booster costs. Two statistical methods were applied in the analysis: (1) state probability method which consists of defining an appropriate state space for the outcome of the random trials, and (2) model simulation method or the Monte Carlo technique. It was found that the model simulation method was easier to formulate while the state probability method required less computing time and was more accurate.

  8. Electronic amplifiers: A compilation

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Several types of amplifiers and amplifier systems are considered. These include preamplifiers, high power amplifiers, buffer and isolation amplifiers, amplifier circuits, and general purpose amplifiers.

  9. Immunisation of chickens with live Salmonella vaccines - Role of booster vaccination.

    PubMed

    Methner, U

    2018-05-17

    It is accepted that booster vaccinations of chickens with live Salmonella vaccines are essential part of vaccinations schemes to induce an effective adaptive immune response. As manufacturer of registered live Salmonella vaccines recommend different times of booster the question raises whether the duration between the first and second immunisation might influence the protective effect against Salmonella exposure. Chickens were immunised with a live Salmonella Enteritidis vaccine on day 1 of age followed by a booster vaccination at different intervals (day 28, 35 or 42 of age) to study the effects on the colonisation and invasion of the Salmonella vaccine strain, the humoral immune response and the efficacy against infection with Salmonella Enteritidis on day 56 of age. Immunisation of all groups resulted in a very effective adaptive immune response and a high degree of protection against severe Salmonella exposure, however, the time of booster had only an unverifiable influence on either the colonisation of the vaccine strain, the development of the humoral immune response or the colonisation of the Salmonella challenge strain. Therefore, the first oral immunisation of the chicks on day 1 of age seems to be of special importance and prerequisite for the development of the effective immune response. A booster immunisation should be carried out, however, the time of booster may vary between week 3 and week 7 of age of the chickens without adversely impact on the efficacy of the adaptive immune response or the protective effects. Copyright © 2018 Elsevier Ltd. All rights reserved.

  10. Advanced Concepts in Josephson Junction Reflection Amplifiers

    NASA Astrophysics Data System (ADS)

    Lähteenmäki, Pasi; Vesterinen, Visa; Hassel, Juha; Paraoanu, G. S.; Seppä, Heikki; Hakonen, Pertti

    2014-06-01

    Low-noise amplification at microwave frequencies has become increasingly important for the research related to superconducting qubits and nanoelectromechanical systems. The fundamental limit of added noise by a phase-preserving amplifier is the standard quantum limit, often expressed as noise temperature . Towards the goal of the quantum limit, we have developed an amplifier based on intrinsic negative resistance of a selectively damped Josephson junction. Here we present measurement results on previously proposed wide-band microwave amplification and discuss the challenges for improvements on the existing designs. We have also studied flux-pumped metamaterial-based parametric amplifiers, whose operating frequency can be widely tuned by external DC-flux, and demonstrate operation at pumping, in contrast to the typical metamaterial amplifiers pumped via signal lines at.

  11. Immunogenicity and reactogenicity of a decennial booster dose of a combined reduced-antigen-content diphtheria-tetanus-acellular pertussis and inactivated poliovirus booster vaccine (dTpa-IPV) in healthy adults.

    PubMed

    Kovac, Martina; Rathi, Niraj; Kuriyakose, Sherine; Hardt, Karin; Schwarz, Tino F

    2015-05-21

    Pertussis in adults and adolescents could be reduced by replacing traditional tetanus and diphtheria (Td) boosters with reduced-antigen-content diphtheria-tetanus-acellular pertussis (dTpa) vaccines. This study evaluated the administration of dTpa-IPV (dTpa-inactivated poliovirus) in adults ten years after they received a booster dose of either dTpa-IPV, dTpa+IPV or Td-IPV in trial NCT01277705. Open multicentre, phase IV study (www.clinicaltrials.govNCT01323959) in which healthy adults, who had received a previous dose of dTpa-IPV, dTpa+IPV or Td-IPV ten years earlier, received a single decennial booster dose of dTpa-IPV (Boostrix-polio, GlaxoSmithKline Vaccines). Blood samples were collected before and one month after booster vaccination. Antibody concentrations against all vaccine antigens were measured and reactogenicity and safety were assessed. A total of 211 subjects (mean age 50.3 years) received vaccination of whom 201 were included in the according-to-protocol cohort for immunogenicity. Before the decennial dTpa-IPV booster, ≥71.0% subjects were seroprotected/seropositive against all vaccine antigens. One month after the booster dose, all subjects were seroprotected against tetanus and poliovirus types 2 and 3; ≥95.7% subjects were seroprotected against diphtheria and ≥98.3% against poliovirus type 1. Anti-pertussis booster responses for the various antigens were observed in ≥76.5% (pertussis toxoid; PT), ≥85.1% (filamentous haemagglutinin; FHA) and ≥63.2% (pertactin; PRN) of subjects. During the 4-day follow-up, the overall incidence of local AEs was 71.6%, 75.0% and 72.2% in dTpa-IPV, dTpa+IPV and Td-IPV groups, respectively. Pain was the most frequent solicited local adverse event (AE; ≥62.7% subjects) and fatigue the most frequent solicited general AE (≥18.5%). No serious AEs were reported during the study. A booster dose of dTpa-IPV was immunogenic and well tolerated in adults who had received a booster dose of either dTpa-IPV, d

  12. Does a Booster Intervention Augment the Preventive Effects of an Abbreviated Version of the Coping Power Program for Aggressive Children?

    PubMed Central

    Lochman, John E.; Baden, Rachel E.; Boxmeyer, Caroline L.; Powell, Nicole P.; Qu, Lixin; Salekin, Karen L.; Windle, Michel

    2013-01-01

    Booster interventions have been presumed to be important methods for maintaining the effects of evidence-based programs for children with behavioral problems, but there has been remarkably little empirical attention to this assumption. The present study examines the effect of a child-oriented booster preventive intervention with children who had previously received an abbreviated version (24 child sessions, 10 parent sessions) of the Coping Power targeted prevention program. Two hundred and forty-one children (152 boys, 89 girls) were screened as having moderate to high levels of aggressive behavior in 4th grade, then half were randomly assigned to receive the abbreviated Coping Power program in 5th grade, and half of the preventive intervention children were then randomly assigned to a Booster condition in 6th grade. The Booster sessions consisted of brief monthly individual contacts, and were primarily with the children. Five assessments across four years were collected from teachers, providing a three-year follow-up for all children who participated in the project. Results indicated that the abbreviated Coping Power program (one-third shorter than the full intervention) had long-term effects in reducing children’s externalizing problem behaviors, proactive and reactive aggression, impulsivity traits and callous-unemotional traits. The Booster intervention did not augment these prevention effects. These findings indicate that a briefer and more readily disseminated form of an evidence-based targeted preventive intervention was effective. The findings have potential implications for policy and guidelines about possible intervention length and booster interventions. PMID:23417235

  13. Implantable neurotechnologies: a review of integrated circuit neural amplifiers.

    PubMed

    Ng, Kian Ann; Greenwald, Elliot; Xu, Yong Ping; Thakor, Nitish V

    2016-01-01

    Neural signal recording is critical in modern day neuroscience research and emerging neural prosthesis programs. Neural recording requires the use of precise, low-noise amplifier systems to acquire and condition the weak neural signals that are transduced through electrode interfaces. Neural amplifiers and amplifier-based systems are available commercially or can be designed in-house and fabricated using integrated circuit (IC) technologies, resulting in very large-scale integration or application-specific integrated circuit solutions. IC-based neural amplifiers are now used to acquire untethered/portable neural recordings, as they meet the requirements of a miniaturized form factor, light weight and low power consumption. Furthermore, such miniaturized and low-power IC neural amplifiers are now being used in emerging implantable neural prosthesis technologies. This review focuses on neural amplifier-based devices and is presented in two interrelated parts. First, neural signal recording is reviewed, and practical challenges are highlighted. Current amplifier designs with increased functionality and performance and without penalties in chip size and power are featured. Second, applications of IC-based neural amplifiers in basic science experiments (e.g., cortical studies using animal models), neural prostheses (e.g., brain/nerve machine interfaces) and treatment of neuronal diseases (e.g., DBS for treatment of epilepsy) are highlighted. The review concludes with future outlooks of this technology and important challenges with regard to neural signal amplification.

  14. Implantable neurotechnologies: a review of integrated circuit neural amplifiers

    PubMed Central

    Greenwald, Elliot; Xu, Yong Ping; Thakor, Nitish V.

    2016-01-01

    Neural signal recording is critical in modern day neuroscience research and emerging neural prosthesis programs. Neural recording requires the use of precise, low-noise amplifier systems to acquire and condition the weak neural signals that are transduced through electrode interfaces. Neural amplifiers and amplifier-based systems are available commercially or can be designed in-house and fabricated using integrated circuit (IC) technologies, resulting in very large-scale integration or application-specific integrated circuit solutions. IC-based neural amplifiers are now used to acquire untethered/portable neural recordings, as they meet the requirements of a miniaturized form factor, light weight and low power consumption. Furthermore, such miniaturized and low-power IC neural amplifiers are now being used in emerging implantable neural prosthesis technologies. This review focuses on neural amplifier-based devices and is presented in two interrelated parts. First, neural signal recording is reviewed, and practical challenges are highlighted. Current amplifier designs with increased functionality and performance and without penalties in chip size and power are featured. Second, applications of IC-based neural amplifiers in basic science experiments (e.g., cortical studies using animal models), neural prostheses (e.g., brain/nerve machine interfaces) and treatment of neuronal diseases (e.g., DBS for treatment of epilepsy) are highlighted. The review concludes with future outlooks of this technology and important challenges with regard to neural signal amplification. PMID:26798055

  15. Space Launch System Booster Passes Major Ground Test

    NASA Image and Video Library

    2015-03-11

    The largest, most powerful rocket booster ever built successfully fired up Wednesday for a major-milestone ground test in preparation for future missions to help propel NASA’s Space Launch System (SLS) rocket and Orion spacecraft to deep space destinations, including an asteroid and Mars. The booster fired for two minutes, the same amount of time it will fire when it lifts the SLS off the launch pad, and produced about 3.6 million pounds of thrust. The test was conducted at the Promontory, Utah test facility of commercial partner Orbital ATK.

  16. Mars Science Laboratory Atlas V First Stage Booster

    NASA Image and Video Library

    2011-09-07

    NASA Administrator Charles Bolden, second from left, talks with United Launch Alliance Vice President of Mission operations Jim Sponnick, along with NASA Mission Manager for Launch Services Wanda Harding, left, White House Fellow Debra Kurshan, right, and NASA Senior Advisor Mike French, background, in front of the United Launch Alliance Atlas V first stage booster, Wednesday, Sept. 7, 2011, at the Cape Canaveral Air Force Station in Cape Canaveral, Fla. The booster will help send NASA's Mars Science Laboratory Curiosity rover to Mars later this year. Photo Credit: (NASA/Bill Ingalls)

  17. InSight Atlas V Booster Prep for Transport

    NASA Image and Video Library

    2018-03-01

    A United Launch Alliance Atlas V booster is prepared for transport to Space Launch Complex 3 at Vandenberg Air Force Base in California. The rocket will launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

  18. Modeling a Common-Source Amplifier Using a Ferroelectric Transistor

    NASA Technical Reports Server (NTRS)

    Sayyah, Rana; Hunt, Mitchell; MacLeond, Todd C.; Ho, Fat D.

    2010-01-01

    This paper presents a mathematical model characterizing the behavior of a common-source amplifier using a FeFET. The model is based on empirical data and incorporates several variables that affect the output, including frequency, load resistance, and gate-to-source voltage. Since the common-source amplifier is the most widely used amplifier in MOS technology, understanding and modeling the behavior of the FeFET-based common-source amplifier will help in the integration of FeFETs into many circuits.

  19. Competence in Lexical Boosters and Nativeness in Academic Writing of English: The Possible Relation

    ERIC Educational Resources Information Center

    Demir, Cüneyt

    2017-01-01

    Boosters are an important metadiscourse device for writers because it creates an emphatic impression in the reader. In addition, the competence of metadiscourse devices such as boosters is crucial in having native-fluency in academic writing. Therefore, this avoidance of using boosters may spawn foreignness in non-native writers' academic texts.…

  20. General view of the Solid Rocket Booster's (SRB) Solid Rocket ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the Solid Rocket Booster's (SRB) Solid Rocket Motor Segments in the Surge Building of the Rotation Processing and Surge Facility at Kennedy Space Center awaiting transfer to the Vehicle Assembly Building and subsequent mounting and assembly on the Mobile Launch Platform. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  1. Ares I First Stage Booster Deceleration System: An Overview

    NASA Technical Reports Server (NTRS)

    King, Ron; Hengel, John E.; Wolf, Dean

    2009-01-01

    In 2005, the Congressional NASA Authorization Act enacted a new space exploration program, the "Vision for Space Exploratien". The Constellation Program was formed to oversee the implementation of this new mission. With an intent not simply to support the International Space Station, but to build a permanent outpost on the Moon and then travel on to explore ever more distant terrains, the Constellation Program is supervising the development of a brand new fleet of launch vehicles, the Ares. The Ares lineup will include two new launch vehicles: the Ares I Crew Launch Vehicle and the Ares V Cargo Launch Vehicle. A crew exploration vehicle, Orion, will be launched on the Ares I. It will be capable of docking with the Space Station, the lunar lander, Altair, and the Earth Departure Stage of Ares V. The Ares V will be capable of lifting both large-scale hardware and the Altair into space. The Ares First Stage Team is tasked with developing the propulsion system necessary to liftoff from the Earth and loft the entire Ares vehicle stack toward low Earth orbit. The Ares I First Stage booster is a 12-foot diameter, five-segment, reusable solid rocket booster derived from the Space Shuttle's four segment reusable solid rocket booster (SRB). It is separated from the Upper Stage through the use of a Deceleration Subsystem (DSS). Booster Tumble Motors are used to induce the pitch tumble following separation from the Upper Stage. The spent Ares I booster must be recoverable using a parachute deceleration system similar to that of the Shuttle SRB heritage system. Since Ares I is much heavier and reenters the Earth's atmosphere from a higher altitude at a much higher velocity than the SRB, all of the parachutes must be redesigned to reliably meet the operational requisites of the new launch vehicles. This paper presents an overview of this new booster deceleration system. It includes comprehensive detail of the parachute deceleration system, its design and deployment sequences

  2. Ultrasensitive low noise voltage amplifier for spectral analysis.

    PubMed

    Giusi, G; Crupi, F; Pace, C

    2008-08-01

    Recently we have proposed several voltage noise measurement methods that allow, at least in principle, the complete elimination of the noise introduced by the measurement amplifier. The most severe drawback of these methods is that they require a multistep measurement procedure. Since environmental conditions may change in the different measurement steps, the final result could be affected by these changes. This problem is solved by the one-step voltage noise measurement methodology based on a novel amplifier topology proposed in this paper. Circuit implementations for the amplifier building blocks based on operational amplifiers are critically discussed. The proposed approach is validated through measurements performed on a prototype circuit.

  3. Shuttle Liquid Fly Back Booster Configuration Options

    NASA Technical Reports Server (NTRS)

    Healy, T. J., Jr.

    1998-01-01

    This paper surveys the basic configuration options available to a Liquid Fly Back Booster (LFBB), integrated with the Space Shuttle system. The background of the development of the LFBB concept is given. The influence of the main booster engine (BME) installations and the Fly Back Engine (FBE) installation on the aerodynamic configurations are also discussed. Limits on the LFBB configuration design space imposed by the existing Shuttle flight and ground elements are also described. The objective of the paper is to put the constrains and design space for an LFBB in perspective. The object of the work is to define LFBB configurations that significantly improve safety, operability, reliability and performance of the Shuttle system and dramatically lower operations costs.

  4. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines, secured on a flatbed truck, is on its way to the Vehicle Assembly Building (VAB), in view in the distance, at the agency's Kennedy Space Center in Florida. It was transported from fabricator Met-Con Inc. in Cocoa, Florida. The platform will be delivered to the VAB, where it will be stored and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1 (EM-1). During EM-1, an uncrewed Orion spacecraft will launch on the SLS to a stable orbit beyond the Moon and return to Earth for a splashdown in the Pacific Ocean.

  5. Input-output Transfer Function Analysis of a Photometer Circuit Based on an Operational Amplifier.

    PubMed

    Hernandez, Wilmar

    2008-01-09

    In this paper an input-output transfer function analysis based on the frequencyresponse of a photometer circuit based on operational amplifier (op amp) is carried out. Opamps are universally used in monitoring photodetectors and there are a variety of amplifierconnections for this purpose. However, the electronic circuits that are usually used to carryout the signal treatment in photometer circuits introduce some limitations in theperformance of the photometers that influence the selection of the op amps and otherelectronic devices. For example, the bandwidth, slew-rate, noise, input impedance and gain,among other characteristics of the op amp, are often the performance limiting factors ofphotometer circuits. For this reason, in this paper a comparative analysis between twophotodiode amplifier circuits is carried out. One circuit is based on a conventional currentto-voltage converter connection and the other circuit is based on a robust current-to-voltageconverter connection. The results are satisfactory and show that the photodiode amplifierperformance can be improved by using robust control techniques.

  6. Space shuttle phase B wind tunnel model and test information. Volume 1: Booster configuration

    NASA Technical Reports Server (NTRS)

    Glynn, J. L.; Poucher, D. E.

    1988-01-01

    Archived wind tunnel test data are available for flyback booster or other alternative recoverable configurations as well as reusable orbiters studied during initial development (Phase B) of the Space Shuttle. Considerable wind tunnel data was acquired by the competing contractors and the NASA Centers for an extensive variety of configurations with an array of wing and body planforms. All contractor and NASA wind tunnel test data acquired in the Phase B development have been compiled into a database and are available for application to current winged flyback or recoverable booster aerodynamic studies. The Space Shuttle Phase B Wind Tunnel Database is structured by vehicle component and configuration type. Basic components include the booster, the orbiter, and the launch vehicle. Booster configuration types include straight and delta wings, canard, cylindrical, retroglide and twin body. Orbiter configuration types include straight and delta wings, lifting body, drop tanks and double delta wings. Launch configurations include booster and orbiter components in various stacked and tandem combinations. This is Volume 1 (Part 2) of the report -- Booster Configuration.

  7. Space shuttle phase B wind tunnel model and test information. Volume 1: Booster configuration

    NASA Technical Reports Server (NTRS)

    Glynn, J. L.; Poucher, D. E.

    1988-01-01

    Archived wind tunnel test data are available for flyback booster or other alternative recoverable configurations as well as reusable orbiters studied during initial development (Phase B) of the Space Shuttle. Considerable wind tunnel data was acquired by the competing contractors and the NASA Centers for an extensive variety of configurations with an array of wing and body planforms. All contractor and NASA wind tunnel test data acquired in the Phase B development have been compiled into a database and are available for application to current winged flyback or recoverable booster aerodynamic studies. The Space Shuttle Phase B Wind Tunnel Database is structured by vehicle component and configuration type. Basic components include the booster, the orbiter and the launch vehicle. Booster configuration types include straight and delta wings, canard, cylindrical, retroglide and twin body. Orbiter configuration types include straight and delta wings, lifting body, drop tanks, and double delta wings. Launch configurations include booster and orbiter components in various stacked and tandem combinations. This is Volume 1 (Part 1) of the report -- Booster Configuration.

  8. Cross-differential amplifier

    NASA Technical Reports Server (NTRS)

    Hajimiri, Seyed-Ali (Inventor); Kee, Scott D. (Inventor); Aoki, Ichiro (Inventor)

    2010-01-01

    A cross-differential amplifier is provided. The cross-differential amplifier includes an inductor connected to a direct current power source at a first terminal. A first and second switch, such as transistors, are connected to the inductor at a second terminal. A first and second amplifier are connected at their supply terminals to the first and second switch. The first and second switches are operated to commutate the inductor between the amplifiers so as to provide an amplified signal while limiting the ripple voltage on the inductor and thus limiting the maximum voltage imposed across the amplifiers and switches.

  9. Cross-differential amplifier

    NASA Technical Reports Server (NTRS)

    Hajimiri, Seyed-Ali (Inventor); Kee, Scott D. (Inventor); Aoki, Ichiro (Inventor)

    2011-01-01

    A cross-differential amplifier is provided. The cross-differential amplifier includes an inductor connected to a direct current power source at a first terminal. A first and second switch, such as transistors, are connected to the inductor at a second terminal. A first and second amplifier are connected at their supply terminals to the first and second switch. The first and second switches are operated to commutate the inductor between the amplifiers so as to provide an amplified signal while limiting the ripple voltage on the inductor and thus limiting the maximum voltage imposed across the amplifiers and switches.

  10. Hybrid matrix amplifier

    DOEpatents

    Martens, J.S.; Hietala, V.M.; Plut, T.A.

    1995-01-03

    The present invention comprises a novel matrix amplifier. The matrix amplifier includes an active superconducting power divider (ASPD) having N output ports; N distributed amplifiers each operatively connected to one of the N output ports of the ASPD; and a power combiner having N input ports each operatively connected to one of the N distributed amplifiers. The distributed amplifier can included M stages of amplification by cascading superconducting active devices. The power combiner can include N active elements. The resulting (N[times]M) matrix amplifier can produce signals of high output power, large bandwidth, and low noise. 6 figures.

  11. Cross-differential amplifier

    NASA Technical Reports Server (NTRS)

    Aoki, Ichiro (Inventor); Hajimiri, Seyed-Ali (Inventor); Kee, Scott D. (Inventor)

    2013-01-01

    A cross-differential amplifier is provided. The cross-differential amplifier includes an inductor connected to a direct current power source at a first terminal. A first and second switch, such as transistors, are connected to the inductor at a second terminal. A first and second amplifier are connected at their supply terminals to the first and second switch. The first and second switches are operated to commutate the inductor between the amplifiers so as to provide an amplified signal while limiting the ripple voltage on the inductor and thus limiting the maximum voltage imposed across the amplifiers and switches.

  12. Hybrid matrix amplifier

    DOEpatents

    Martens, Jon S.; Hietala, Vincent M.; Plut, Thomas A.

    1995-01-01

    The present invention comprises a novel matrix amplifier. The matrix amplifier includes an active superconducting power divider (ASPD) having N output ports; N distributed amplifiers each operatively connected to one of the N output ports of the ASPD; and a power combiner having N input ports each operatively connected to one of the N distributed amplifiers. The distributed amplifier can included M stages of amplification by cascading superconducting active devices. The power combiner can include N active elements. The resulting (N.times.M) matrix amplifier can produce signals of high output power, large bandwidth, and low noise.

  13. Cross-differential amplifier

    NASA Technical Reports Server (NTRS)

    Hajimiri, Seyed-Ali (Inventor); Kee, Scott D. (Inventor); Aoki, Ichiro (Inventor)

    2008-01-01

    A cross-differential amplifier is provided. The cross-differential amplifier includes an inductor connected to a direct current power source at a first terminal. A first and second switch, such as transistors, are connected to the inductor at a second terminal. A first and second amplifier are connected at their supply terminals to the first and second switch. The first and second switches are operated to commutate the inductor between the amplifiers so as to provide an amplified signal while limiting the ripple voltage on the inductor and thus limiting the maximum voltage imposed across the amplifiers and switches.

  14. 76 FR 11680 - Digital Low Power Television, Television Translator, and Television Booster Stations and Digital...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ...] Digital Low Power Television, Television Translator, and Television Booster Stations and Digital Class A... Commission's Rules to Establish Rules for Digital Low Power, Television Translator, and Television Booster... Digital Low Power Television Translator, Television Booster Stations, and to Amend Rules for Digital Class...

  15. Liquid flyback booster pre-phase: A study assessment

    NASA Technical Reports Server (NTRS)

    Peterson, W.; Ankney, W.; Bell, J.; Berning, M.; Bryant, L.; Bufkin, A.; Cain, L.; Caram, J.; Cockrell, B.; Curry, D.

    1994-01-01

    The concept of a flyback booster has been around since early in the shuttle program. The original two-stage shuttle concepts used a manned flyback booster. These boosters were eliminated from the program for funding and size reasons. The current shuttle uses two Redesigned Solid Rocket Motors (RSRM's), which are recovered and refurbished after each flight; this is one of the major cost factors of the program. Replacement options have been studied over the past ten years. The conclusion reached by the most recent study is that the liquid flyback booster (LFBB) is the only competitive option from a life-cycle cost perspective. The purpose of this study was to assess the feasibility and practicality of LFBB's. The study provides an expansion of the recommendations made during the aforementioned study. The primary benefits are the potential for enhanced reusability and a reduction of recurring costs. The potential savings in vehicle turnaround could offset the up-front costs. Development of LFBB's requires a commitment to the shuttle program for 20 to 30 years. LFBB's also offer enhanced safety and abort capabilities. Currently, any failure of an RSRM can be considered catastrophic, since there are no intact abort capabilities during the burn of the RSRM's. The performance goal of the LFBB's was to lift a fully loaded orbiter under optimal conditions, so as not to be the limiting factor of the performance capability of the shuttle. In addition, a final benefit is the availability of growth paths for applications other than shuttle.

  16. Early Beam Injection Scheme for the Fermilab Booster: A Path for Intensity Upgrade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhat, C. M.

    Over the past decade, Fermilab has focused efforts on the intensity frontier physics and is committed to increase the average beam power delivered to the neutrino and muon programs substantially. Many upgrades to the existing injector accelerators, namely, the current 400 MeV LINAC and the Booster, are in progress under the Proton Improvement Plan (PIP). Proton Improvement Plan-II (PIP-II) proposes to replace the existing 400 MeV LINAC by a new 800 MeV LINAC, as an injector to the Booster which will increase Booster output power by nearly a factor of two from the PIP design value by the end ofmore » its completion. In any case, the Fermilab Booster is going to play a very significant role for nearly next two decades. In this context, I have developed and investigated a new beam injection scheme called "early injection scheme" (EIS) for the Booster with the goal to significantly increase the beam intensity output from the Booster thereby increasing the beam power to the HEP experiments even before PIP-II era. The scheme, if implemented, will also help improve the slip-stacking efficiency in the MI/RR. Here I present results from recent simulations, beam studies, current status and future plans for the new scheme.« less

  17. Isolated thermocouple amplifier system for stirred fixed-bed gasifier

    DOEpatents

    Fasching, George E.

    1992-01-01

    A sensing system is provided for determining the bed temperature profile of the bed of a stirred, fixed-bed gasifier including a plurality of temperature sensors for sensing the bed temperature at different levels, a transmitter for transmitting data based on the outputs of the sensors to a remote operator's station, and a battery-based power supply. The system includes an isolation amplifier system comprising a plurality of isolation amplifier circuits for amplifying the outputs of the individual sensors. The isolation amplifier circuits each comprise an isolation operational amplifier connected to a sensor; a first "flying capacitor" circuit for, in operation, controlling the application of power from the power supply to the isolation amplifier; an output sample and hold circuit connected to the transmitter; a second "flying capacitor" circuit for, in operation, controlling the transfer of the output of the isolation amplifier to the sample and hold circuit; and a timing and control circuit for activating the first and second capacitor circuits in a predetermined timed sequence.

  18. Microwave power amplifiers based on AlGaN/GaN transistors with a two-dimensional electron gas

    NASA Astrophysics Data System (ADS)

    Vendik, O. G.; Vendik, I. B.; Tural'chuk, P. A.; Parnes, Ya. M.; Parnes, M. D.

    2016-11-01

    A technique for synthesis of microwave power amplifiers based on transistors with a AlGaN/GaN heterojunction is discussed. Special focus is on the development of a technique for synthesis of transformation circuits of the power amplifier to increase efficiency with a retained high output power. The use of independent matching at the harmonic frequencies and fundamental frequency makes it possible to control the attainable efficiency in a wide frequency band along with the total suppression of harmonics beyond the operational band. Microwave power amplifiers for operation at 4 and 9 GHz have been developed and experimentally investigated.

  19. Theoretical Analysis and Bench Tests of a Control-Surface Booster Employing a Variable Displacement Hydraulic Pump

    NASA Technical Reports Server (NTRS)

    Mathews, Charles W.; Kleckner, Harold F.

    1947-01-01

    The NACA is conducting a general investigation of servo-mechanisms for use in powering aircraft control surfaces. This paper presents a theoretical analysis and the results of bench tests of a control-booster system which employs a variable displacement hydraulic pump. The booster is intended for use in a flight investigation to determine the effects of various booster parameters on the handling qualities of airplanes. Such a flight investigation would aid in formulating specific requirements concerning the design of control boosters in general. Results of the theoretical analysis and the bench tests indicate that the subject booster is representative of types which show promise of satisfactory performance. The bench tests showed that the following desirable features were inherent in this booster system: (1) No lost motion or play in any part of the system; (2) no detectable lag between motion of the contra1 stick and control surface; and (3) Good agreement between control displacements and stick-force variations with no hysteresis in the stick-force characteristics. The final design configuration of this booster system showed no tendency to oscillate, overshoot, or have other undesirable transient characteristics common to boosters.

  20. Booster seat law enforcement : examples from Delaware, New Jersey, Pennsylvania, and Washington.

    DOT National Transportation Integrated Search

    2010-02-01

    The objective of this study was to evaluate the implementation of State booster seat laws : (enhanced child restraint laws) and examine the most effective strategies that law enforcement agencies can : use to enforce booster seat laws. The research i...

  1. X-Band, 17-Watt Solid-State Power Amplifier

    NASA Technical Reports Server (NTRS)

    Mittskus, Anthony; Stone, Ernest; Boger, William; Burgess, David; Honda, Richard; Nuckolls, Carl

    2005-01-01

    An advanced solid-state power amplifier that can generate an output power of as much as 17 W at a design operating frequency of 8.4 GHz has been designed and constructed as a smaller, lighter, less expensive alternative to traveling-wave-tube X-band amplifiers and to prior solid-state X-band power amplifiers of equivalent output power. This amplifier comprises a monolithic microwave integrated circuit (MMIC) amplifier module and a power-converter module integrated into a compact package (see Figure 1). The amplifier module contains an input variable-gain amplifier (VGA), an intermediate driver stage, a final power stage, and input and output power monitors (see Figure 2). The VGA and the driver amplifier are 0.5-m GaAs-based metal semiconductor field-effect transistors (MESFETs). The final power stage contains four parallel high-efficiency, GaAs-based pseudomorphic high-electron-mobility transistors (PHEMTs). The gain of the VGA is voltage-variable over a range of 10 to 24 dB. To provide for temperature compensation of the overall amplifier gain, the gain-control voltage is generated by an operational-amplifier circuit that includes a resistor/thermistor temperature-sensing network. The driver amplifier provides a gain of 14 dB to an output power of 27 dBm to drive the four parallel output PHEMTs, each of which is nominally capable of putting out as much as 5 W. The driver output is sent to the input terminals of the four parallel PHEMTs through microstrip power dividers; the outputs of these PHEMTs are combined by microstrip power combiners (which are similar to the microstrip power dividers) to obtain the final output power of 17 W.

  2. Survey of Advanced Booster Options for Potential Shuttle Derivative Vehicles

    NASA Technical Reports Server (NTRS)

    Sackheim, Robert L.; Ryan, Richard; Threet, Ed; Kennedy, James W. (Technical Monitor)

    2001-01-01

    A never-ending major goal for the Space Shuttle program is to continually improve flight safety, as long as this launch system remains in operational service. One of the options to improve system safety and to enhance vehicle performance as well, that has been seriously studied over the past several decades, is to replace the existing strap-on four segment solid rocket boosters (SRB's) with more capable units. A number of booster upgrade options have been studied in some detail, ranging from five segment solids through hybrids and a wide variety of liquid strap-ons (both pressure and pump fed with various propellants); all the way to a completely reusable liquid fly back booster (complete with air breathing engines for controlled landing and return). All of these possibilities appear to offer improvements in varying degrees; and each has their strengths and weaknesses from both programmatic and technical points of view. The most beneficial booster upgrade/design, if the shuttle program were to continue long enough to justify the required investment, would be an approach that greatly increased both vehicle and crew safety. This would be accomplished by increasing the minimum range/minimum altitude envelope that would readily allow abort to orbit (ATO), possibly even to zero/zero, and possibly reduce or eliminate the Return to Launch Site (RTLS) and even the Trans Atlantic Landing (TAL) abort mode requirements. This paper will briefly survey and discuss all of the various booster'upgrade options studied previously, and compare their relative attributes. The survey will explicitly discuss, in summary comparative form, options that include: five segment solids; several hybrid possibilities; pressure and/or pump-fed liquids using either LO2/kerosene, H2O/kerosene and LO2/J2, any of which could be either fully expendable, partly or fully reusable; and finally a fully reusable liquid fly back booster system, with a number of propellant and propulsion system options

  3. Orion EM-1 Booster Preps - Aft Skirt Preps/Painting

    NASA Image and Video Library

    2016-10-28

    A technician with Orbital ATK, prime contractor for the Space Launch System (SLS) Booster, preps a section of the right hand aft skirt for primer and paint in a support building at the Hangar AF facility at Cape Canaveral Air Force Station in Florida. The space shuttle-era aft skirt will be used on the right hand booster of NASA's SLS rocket for Exploration Mission 1 (EM-1). NASA is preparing for EM-1, deep space missions, and the Journey to Mars.

  4. The effectiveness of booster sessions in CBT treatment for child and adolescent mood and anxiety disorders.

    PubMed

    Gearing, Robin E; Schwalbe, Craig S J; Lee, RaeHyuck; Hoagwood, Kimberly E

    2013-09-01

    To investigate the effects of booster sessions in cognitive behavioral therapy (CBT) for children and adolescents with mood or anxiety disorders, whereas controlling for youth demographics (e.g., gender, age), primary diagnosis, and intervention characteristics (e.g., treatment modality, number of sessions). Electronic databases were searched for CBT interventions for youth with mood and anxiety disorders. Fifty-three (k = 53) studies investigating 1,937 youth met criteria for inclusion. Booster sessions were examined using two case-controlled effect sizes: pre-post and pre-follow-up (6 months) effect sizes and employing weighted least squares (WLSs) regressions. Meta-analyses found pre-post studies with booster sessions had a larger effect size r = .58 (k = 15; 95% CI = 0.52-0.65; P < .01) than those without booster sessions r = .45 (k = 38; 95% CI = 0.41-0.49; P < .001). In the WLS regression analyses, controlling for demographic factors, primary diagnosis, and intervention characteristics, studies with booster sessions showed larger pre-post effect sizes than those without booster sessions (B = 0.13, P < .10). Similarly, pre-follow-up studies with booster sessions showed a larger effect size r = .64 (k = 10; 95% CI = 0.57-0.70; P < .10) than those without booster sessions r = .48 (k = 20; 95% CI = 0.42-0.53; P < .01). Also, in the WLS regression analyses, pre-follow-up studies showed larger effect sizes than those without booster sessions (B = 0.08, P < .01) after accounting for all control variables. Result suggests that CBT interventions with booster sessions are more effective and the effect is more sustainable for youth managing mood or anxiety disorders than CBT interventions without booster sessions. © 2013 Wiley Periodicals, Inc.

  5. Reduced transposed flicker noise in microwave oscillators using gaas-based feedforward amplifiers.

    PubMed

    Everard, Jeremy K A; Broomfield, Carl D

    2007-06-01

    Transposed flicker noise reduction and removal is demonstrated in 7.6 GHz microwave oscillators for offsets greater than 10 kHz. This is achieved by using a GaAs-based feedforward power amplifier as the oscillation-sustaining stage and incorporating a limiter and resonator elsewhere in the loop. 20 dB noise suppression is demonstrated at 12.5 kHz offset when the error correcting amplifier is switched on. Three oscillator pairs have been built. A transmission line feedback oscillator with a Qo of 180 and two sapphire-based, dielectric resonator oscillators (DROs) with a Qo of 44,500. The difference between the two DROs is a change in the limiter threshold power level of 10 dB. The phase noise rolls-off at (1/f)(2) for offsets greater than 10 kHz for the transmission line oscillator and is set by the thermal noise to within 0-1 dB of the theoretical minimum. The noise performance of the DROs is within 6-12 dB of the theory. Possible reasons for this discrepancy are presented.

  6. Common base amplifier with 7 - dB gain at 176 GHz in InP mesa DHBT technology

    NASA Technical Reports Server (NTRS)

    Samoska, Lorene; Paidi, V.; Griffith, Z.; Dahlstrom, M.; Wei, Y.; Urteaga, M.; Rodell, M. J. W.; Fung, A.

    2004-01-01

    We report a single stage tunded amplifier that exhibits 7 dB small signal gain at 176 GHz. Common Base topology is chosen as it has the best maximum stable gain (MSG) in this frequency band when compared to common emitter and common collector topologies. The amplifiers are designed and fabricated in InP mesa double heterojunction bipolar transistor (DHBT) technology.

  7. Pr3 + -doped GeSx-based glasses for fiber amplifiers at 1.3 µm

    NASA Astrophysics Data System (ADS)

    Simons, D. R.; Faber, A. J.; de Waal, H.

    1995-03-01

    The photoluminescence properties of Pr3+ -doped GeS x -based glasses are studied and compared with those of other sulfide and fluoride glasses. The possibility of highly pump-power-efficient fiber amplifiers based on these GeSx-containing glasses in the telecommunications window at 1.3 mu m is discussed.

  8. First demonstration of high-order QAM signal amplification in PPLN-based phase sensitive amplifier.

    PubMed

    Umeki, T; Tadanaga, O; Asobe, M; Miyamoto, Y; Takenouchi, H

    2014-02-10

    We demonstrate the phase sensitive amplification of a high-order quadrature amplitude modulation (QAM) signal using non-degenerate parametric amplification in a periodically poled lithium niobate (PPLN) waveguide. The interaction between the pump, signal, and phase-conjugated idler enables us to amplify arbitrary phase components of the signal. The 16QAM signals are amplified without distortion because of the high gain linearity of the PPLN-based phase sensitive amplifier (PSA). Both the phase and amplitude noise reduction capabilities of the PSA are ensured. Phase noise cancellation is achieved by using the interaction with the phase-conjugated idler. A degraded signal-to-noise ratio (SNR) is restored by using the gain difference between a phase-correlated signal-idler pair and uncorrelated excess noise. The applicability of the simultaneous amplification of multi-carrier signals and the amplification of two independent polarization signals are also confirmed with a view to realizing ultra-high spectrally efficient signal amplification.

  9. Radiofrequency amplifier based on a dc superconducting quantum interference device

    DOEpatents

    Hilbert, Claude; Martinis, John M.; Clarke, John

    1986-01-01

    A low noise radiofrequency amplifier (10), using a dc SQUID (superconducting quantum interference device) as the input amplifying element. The dc SQUID (11) and an input coil (12) are maintained at superconductivity temperatures in a superconducting shield (13), with the input coil (12) inductively coupled to the superconducting ring (17) of the dc SQUID (11). A radiofrequency signal from outside the shield (13) is applied to the input coil (12), and an amplified radiofrequency signal is developed across the dc SQUID ring (17) and transmitted to exteriorly of the shield (13). A power gain of 19.5.+-.0.5 dB has been achieved with a noise temperature of 1.0.+-.0.4 K. at a frequency of 100 MHz.

  10. Multifrequency Raman amplifiers

    NASA Astrophysics Data System (ADS)

    Barth, Ido; Fisch, Nathaniel J.

    2018-03-01

    In its usual implementation, the Raman amplifier features only one pump carrier frequency. However, pulses with well-separated frequencies can also be Raman amplified while compressed in time. Amplification with frequency-separated pumps is shown to hold even in the highly nonlinear, pump-depletion regime, as derived through a fluid model, and demonstrated via particle-in-cell simulations. The resulting efficiency is similar to single-frequency amplifiers, but, due to the beat-wave waveform of both the pump lasers and the amplified seed pulses, these amplifiers feature higher seed intensities with a shorter spike duration. Advantageously, these amplifiers also suffer less noise backscattering, because the total fluence is split between the different spectral components.

  11. Optimal packing for cascaded regenerative transmission based on phase sensitive amplifiers.

    PubMed

    Sorokina, Mariia; Sygletos, Stylianos; Ellis, Andrew D; Turitsyn, Sergei

    2013-12-16

    We investigate the transmission performance of advanced modulation formats in nonlinear regenerative channels based on cascaded phase sensitive amplifiers. We identify the impact of amplitude and phase noise dynamics along the transmission line and show that after a cascade of regenerators, densely packed single ring PSK constellations outperform multi-ring constellations. The results of this study will greatly simplify the design of future nonlinear regenerative channels for ultra-high capacity transmission.

  12. Implications of a 20-Hz Booster cycle-rate for Slip-stacking

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eldred, Jeffrey; Zwaska, Robert

    2014-06-10

    We examine the potential impacts to slip-stacking from a change of the Booster cycle-rate from 15- to 20-Hz. We find that changing the Booster cycle-rate to 20-Hz would greatly increase the slip-stacking bucket area, while potentially requiring greater usage of the Recycler momentum aperture and additional power dissipation in the RF cavities. In particular, the losses from RF interference can be reduced by a factor of 4-10 (depending on Booster beam longitudinal parameters). We discuss the aspect ratio and beam emittance requirements for efficient slip-stacking in both cycle-rate cases. Using a different injection scheme can eliminate the need for greatermore » momentum aperture in the Recycler.« less

  13. Laser amplifier chain

    DOEpatents

    Hackel, R.P.

    1992-10-20

    A laser amplifier chain has a plurality of laser amplifiers arranged in a chain to sequentially amplify a low-power signal beam to produce a significantly higher-power output beam. Overall efficiency of such a chain is improved if high-gain, low efficiency amplifiers are placed on the upstream side of the chain where only a very small fraction of the total pumped power is received by the chain and low-gain, high-efficiency amplifiers are placed on the downstream side where a majority of pumping energy is received by the chain. 6 figs.

  14. Laser amplifier chain

    DOEpatents

    Hackel, Richard P.

    1992-01-01

    A laser amplifier chain has a plurality of laser amplifiers arranged in a chain to sequentially amplify a low-power signal beam to produce a significantly higher-power output beam. Overall efficiency of such a chain is improved if high-gain, low efficiency amplifiers are placed on the upstream side of the chain where only a very small fraction of the total pumped power is received by the chain and low-gain, high-efficiency amplifiers are placed on the downstream side where a majority of pumping energy is received by the chain.

  15. Wideband pulse amplifiers for the NECTAr chip

    NASA Astrophysics Data System (ADS)

    Sanuy, A.; Delagnes, E.; Gascon, D.; Sieiro, X.; Bolmont, J.; Corona, P.; Feinstein, F.; Glicenstein, J.-F.; Naumann, C. L.; Nayman, P.; Ribó, M.; Tavernet, J.-P.; Toussenel, F.; Vincent, P.; Vorobiov, S.

    2012-12-01

    The NECTAr collaboration's FE option for the camera of the CTA is a 16 bits and 1-3 GS/s sampling chip based on analog memories including most of the readout functions. This works describes the input amplifiers of the NECTAr ASIC. A fully differential wideband amplifier, with voltage gain up to 20 V/V and a BW of 400 MHz. As it is impossible to design a fully differential OpAmp with an 8 GHz GBW product in a 0.35 CMOS technology, an alternative implementation based on HF linearized transconductors is explored. The output buffer is a class AB miller operational amplifier, with special non-linear current boost.

  16. Optically pre-amplified lidar-radar

    NASA Astrophysics Data System (ADS)

    Morvan, Loic; Dolfi, Daniel; Huignard, Jean-Pierre

    2001-09-01

    We present the concept of an optically pre-amplified intensity modulated lidar, where the modulation frequency is in the microwave domain (1-10 GHz). Such a system permits to combine directivity of laser beams with mature radar processing. As an intensity modulated or dual-frequency laser beam is directed on a target, the backscattered intensity is collected by an optical system, pass through an optical preamplifier, and is detected on a high speed photodiode in a direct detection scheme. A radar type processing permits then to extract range, speed and identification information. The association of spatially multimode amplifier and direct detection allows low sensitivity to atmospheric turbulence and large field of view. We demonstrated theoretically that optical pre-amplification can greatly enhance sensitivity, even in spatially multimode amplifiers, such as free-space amplifier or multimode doped fiber. Computed range estimates based on this concept are presented. Laboratory demonstrations using 1 to 3 GHz modulated laser sources and >20 dB gain in multimode amplifiers are detailed. Preliminary experimental results on range and speed measurements and possible use for large amplitude vibrometry will be presented.

  17. Long-term persistence of protective antibodies in Dutch adolescents following a meningococcal serogroup C tetanus booster vaccination.

    PubMed

    van Ravenhorst, Mariëtte B; Marinovic, Axel Bonacic; van der Klis, Fiona R M; van Rooijen, Debbie M; van Maurik, Marjan; Stoof, Susanne P; Sanders, Elisabeth A M; Berbers, Guy A M

    2016-12-07

    Due to waning immunity, infant vaccination with meningococcal serogroup C conjugated (MenCC) vaccines is insufficient to maintain long-term individual protection. Adolescent booster vaccination is thought to offer direct protection against invasive meningococcal disease (IMD) but also to reduce meningococcal carriage and transmission and in this way establish herd protection in the population. Previously, we studied antibody levels after adolescent MenCC booster vaccination. In the present study, the adolescent vaccinees were revisited after three years to determine antibody persistence and to predict long-term protection. Meningococcal serogroup C tetanus toxoid conjugated (MenC-TT) vaccine was administered to 10-, 12- and 15-year old participants who had been primed nine years earlier with a single dose of MenC-TT vaccine. Blood samples were collected before, 1month, 1year and 3years after the adolescent booster vaccination. Functional antibody levels were measured with serum bactericidal assay using rabbit complement (rSBA). Meningococcal serogroup C polysaccharide and tetanus toxoid specific antibody levels were measured using fluorescent-bead-based multiplex immunoassay. Long-term protection was estimated using longitudinal multilevel antibody decay modeling. Of the original 268 participants, 201 (75%) were revisited after 3years. All participants still had an rSBA titer above the protective threshold of ⩾8 and 98% ⩾128. The 15-year-olds showed the highest antibody titers. Using a bi-exponential decay model, the median time to fall below the protection threshold (rSBA titer <8) was 16.3years, 45.9years and around 270years following the booster for the 10-, 12- and 15-year-olds, respectively. After a first steep decline in antibody levels in the first year after the booster, antibody levels slowly declined between one and three years post-booster. A routine MenC-TT booster vaccination for adolescents in the Netherlands will likely provide long

  18. Ultra-short-course booster is effective in recurrent grass pollen-induced allergic rhinoconjunctivitis.

    PubMed

    Pfaar, O; Lang, S; Pieper-Fürst, U; Astvatsatourov, A; Gerich, F; Klimek, L; Kramer, M F; Reydelet, Y; Shah-Hosseini, K; Mösges, R

    2018-01-01

    A relevant proportion of allergic rhinoconjunctivitis (ARC) patients experience recurrent symptoms after successfully completing allergen immunotherapy (AIT). This prospective, controlled, noninterventional study used internationally standardized instruments to determine the clinical effects of a preseasonal, ultra-short-course booster AIT on clinical outcome parameters. This two-arm study included patients aged ≥12 years with recurrent grass pollen-induced seasonal AR who had completed a successful course of any grass pollen AIT at least 5 years before enrolment. Overall, 56 patients received one preseasonal short-course booster AIT using tyrosine-absorbed grass pollen allergoids containing the adjuvant monophosphoryl lipid A (MPL ® ); 51 control patients received symptomatic medication. The combined symptom and medication score (CSMS) was recorded in the (peak) grass pollen season. Furthermore, concomitant (antiallergic) medication use, the patients' state of health, Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) results and safety/tolerability of the treatment were assessed. The CSMS in the peak grass pollen season was significantly lower in the booster AIT group (Δ=38.4%, P<.01). Moreover, significantly more patients in this group used no concomitant antiallergic medication throughout the peak grass pollen season. Twice as many patients in the booster AIT group as in the control group reported having a better state of health than in the preceding season. MiniRQLQ results showed significant differences favouring the booster AIT. The booster AIT was generally well tolerated, with only two patients reporting mild, grade 1 systemic adverse events. Booster AIT using tyrosine-absorbed allergoids containing the adjuvant MPL ® effectively prevents re-occurrence of symptoms in patients with grass pollen-induced ARC. © 2017 The Authors. Allergy Published by John Wiley & Sons Ltd.

  19. Persistence of antibodies six years after booster vaccination with inactivated vaccine against Japanese encephalitis.

    PubMed

    Paulke-Korinek, Maria; Kollaritsch, Herwig; Kundi, Michael; Zwazl, Ines; Seidl-Friedrich, Claudia; Jelinek, Tomas

    2015-07-09

    Japanese Encephalitis (JE) virus occurs in wide regions of Asia with over 3 billion people living in areas at risk for JE. An estimated 68,000 clinical cases of JE occur every year, and vaccination is the most effective prophylactic measure. One internationally licensed vaccine containing the inactivated JE virus strain SA14-14-2 is Ixiaro (Valneva, Austria). According to recommendations, basic immunization consists of vaccinations on day 0, day 28, and a booster dose 12-24 months later. Protection in terms of neutralizing antibody titers has been assessed up to 12 months after the third dose of the vaccine. The current investigation was designed to evaluate antibody decline over time and to predict long-term duration of seroprotection after a booster dose. In a preceding trial, volunteers received basic immunization (day 0, day 28) and one booster dose against JE 15 months later. A follow up blood draw 6 years following their booster dose was carried out in 67 subjects. For antibody testing, a 50% plaque reduction neutralization test (PRNT50-test) was used. PRNT50 values of 10 and above are surrogate levels of protection according to WHO standards. Seventy-six months following the booster dose, 96% of the tested subjects had PRNT50 titers of 10 or higher. Geometric mean titer (GMT) was 148 (95% CI confidence interval: 107-207). Antibody titers were lower in volunteers 50 years of age and older. Vaccination history against other flaviviruses (yellow fever or tick borne encephalitis) did not significantly influence PRNT50 titers. A two-step log-linear decline model predicted protection against JE of approximately 14 years after the booster dose. Six years after a booster dose against JE, long-term protection could be demonstrated. According to our results, further booster doses should be scheduled 10 years following the first booster dose. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Multifrequency Raman amplifiers

    DOE PAGES

    Barth, Ido; Fisch, Nathaniel J.

    2018-03-08

    In its usual implementation, the Raman amplifier features only one pump carrier frequency. However, pulses with well-separated frequencies can also be Raman amplified while compressed in time. Amplification with frequency-separated pumps is shown to hold even in the highly nonlinear, pump-depletion regime, as derived through a fluid model, and demonstrated via particle-in-cell (PIC) simulations. The resulting efficiency is similar to single-frequency amplifiers, but, due to the beat-wave waveform of both the pump lasers and the amplified seed pulses, these amplifiers feature higher seed intensities with a shorter spike duration. Advantageously, these amplifiers also suffer less noise backscattering, because the totalmore » fluence is split between the different spectral components.« less

  1. Multifrequency Raman amplifiers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barth, Ido; Fisch, Nathaniel J.

    In its usual implementation, the Raman amplifier features only one pump carrier frequency. However, pulses with well-separated frequencies can also be Raman amplified while compressed in time. Amplification with frequency-separated pumps is shown to hold even in the highly nonlinear, pump-depletion regime, as derived through a fluid model, and demonstrated via particle-in-cell (PIC) simulations. The resulting efficiency is similar to single-frequency amplifiers, but, due to the beat-wave waveform of both the pump lasers and the amplified seed pulses, these amplifiers feature higher seed intensities with a shorter spike duration. Advantageously, these amplifiers also suffer less noise backscattering, because the totalmore » fluence is split between the different spectral components.« less

  2. Booster Breaks in the workplace: participants’ perspectives on health-promoting work breaks

    PubMed Central

    Taylor, Wendell C.; King, Kathryn E.; Shegog, Ross; Paxton, Raheem J.; Evans-Hudnall, Gina L.; Rempel, David M.; Chen, Vincent; Yancey, Antronette K.

    2013-01-01

    Increasing sedentary work has been associated with greater cardiovascular and metabolic risk, as well as premature mortality. Interrupting the sedentary workday with health-promoting work breaks can counter these negative health effects. To examine the potential sustainability of work-break programs, we assessed the acceptance of these breaks among participants in a Booster Break program. We analyzed qualitative responses from 35 participants across five worksites where one 15-min physical activity break was taken each workday. Two worksites completed a 1-year intervention and three worksites completed a 6-month intervention. Responses to two open-ended questions about the acceptance and feasibility of Booster Breaks were obtained from a survey administered after the intervention. Three themes for benefits and two themes for barriers were identified. The benefit themes were (i) reduced stress and promoted enjoyment, (ii) increased health awareness and facilitated behavior change, and (iii) enhanced workplace social interaction. The barrier themes were the need for (iv) greater variety in Booster Break routines and (v) greater management support. This study provides empirical support for the acceptance and feasibility of Booster Breaks during the workday. Emphasizing the benefits and minimizing the barriers are strategies that can be used to implement Booster Breaks in other workplaces. PMID:23466367

  3. 78 FR 29062 - Signal Booster Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 2 [WT Docket No. 10-4; FCC 13-21] Signal Booster Rules AGENCY: Federal Communications Commission. ACTION: Final rule; correcting amendment. SUMMARY: The Federal Communications Commission published in the Federal Register of 78 FR 21555, April 11, 2013, a...

  4. Mercury: testing of the Little Joe booster

    NASA Image and Video Library

    1959-08-02

    Testing of the Little Joe booster on its launcher. The launcher is positioned at its normal launch angle of 80 degrees. Joseph Shortal wrote (vol. 3, p. 33): The Little Joe booster was assembled at Wallops on its special launcher in a vertical attitude. It is shown in the on the left with the work platform in place. The launcher was located on a special concrete slab in Launching Area 1. The capsule was lowered onto the booster by crane.... After the assembly was completed, the scaffolding was disassembled and the launcher pitched over to its normal launch angle of 80 degrees.... Little Joe had a diameter of 80 inches and an overall length, including the capsule and escape tower of 48 feet. The total weight at launch was about 43,000 pounds. The overall span of the stabilizing fins was 21.3 feet. Although in comparison with the overall Mercury Project, Little Joe was a simple undertaking, the fact that an attempt was made to condense a normal two-year project into a 6-month one with in house labor turned it into a major undertaking for Langley. -- Published in Joseph A. Shortal, History of Wallops Station: Origins and Activities Through 1949, (Wallops Island, VA: National Aeronautics and Space Administration, Wallops Station, nd), Comment Edition.

  5. Boosters and barriers for direct cardiac reprogramming.

    PubMed

    Talkhabi, Mahmood; Zonooz, Elmira Rezaei; Baharvand, Hossein

    2017-06-01

    Heart disease is currently the most significant cause of morbidity and mortality worldwide, which accounts for approximately 33% of all deaths. Recently, a promising and alchemy-like strategy has been developed called direct cardiac reprogramming, which directly converts somatic cells such as fibroblasts to cardiac lineage cells such as cardiomyocytes (CMs), termed induced CMs or iCMs. The first in vitro cardiac reprogramming study, mediated by cardiac transcription factors (TFs)-Gata4, Tbx5 and Mef2C-, was not enough efficient to produce an adequate number of fully reprogrammed, functional iCMs. As a result, numerous combinations of cardiac TFs exist for direct cardiac reprogramming of mouse and human fibroblasts. However, the efficiency of direct cardiac reprogramming remains low. Recently, a number of cellular and molecular mechanisms have been identified to increase the efficiency of direct cardiac reprogramming and the quality of iCMs. For example, microgrooved substrate, cardiogenic growth factors [VEGF, FGF, BMP4 and Activin A], and an appropriate stoichiometry of TFs boost the direct cardiac reprogramming. On the other hand, serum, TGFβ signaling, activators of epithelial to mesenchymal transition, and some epigenetic factors (Bmi1 and Ezh2) are barriers for direct cardiac reprogramming. Manipulating these mechanisms by the application of boosters and removing barriers can increase the efficiency of direct cardiac reprogramming and possibly make iCMs reliable for cell-based therapy or other potential applications. In this review, we summarize the latest trends in cardiac TF- or miRNA-based direct cardiac reprogramming and comprehensively discuses all molecular and cellular boosters and barriers affecting direct cardiac reprogramming. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. [Immunogenicity and safety of a booster dose of inactivated polio vaccine].

    PubMed

    Li, Xiao-mei; Zhang, Zhu-jia-zi; Wang, Hai-hong; Liu, Fang; Zhang, Li-wen; Chu, Ping; Xu, Ying; Zhang, He-run; Li, Juan; Liu, Dong-lei; Lu, Li

    2013-10-01

    To evaluate the immunogenicity and safety of a boost dose of inactivated polio vaccine (IPV) among children aged 18 months who had been administered with primary doses of IPV. Form 2011 to 2012, a total of 97 children were enrolled in the present study who were vaccinated with IPV at 2, 3, 4 months of age and boosted with the same vaccine at 18 months of age. Anti-poliovirus neutralizing antibody titers in serum were measured before and after booster vaccination, geometric mean titers (GMT) and seroprotection rate were calculated. Adverse events occurring within 30 days after booster vaccination were observed, including pain, redness/swelling and induration at the injection site, fever, vomit, abnormal crying, drowsiness, loss of appetite, irritability, and all other physical discomfort and related medications were also recorded. A descriptive analysis was performed for the safety assessment. Immunogenicity was assessed in 84 subjects. The pre-booster seropositivity rates of neutralizing antibody against poliovirus type 1, 2, 3 before booster were all 100% (84/84) and the corresponding GMT (95% CI) was 1: 148.5 (116.49-189.29) , 1: 237.68 (178.39-316.67) and 1: 231.87 (181.27-296.58) , respectively. The seropositivity rates of neutralizing antibody against the three types of poliovirus after booster were all 100% (84/84) and the corresponding GMT (95% CI) was 1: 1612.14 (1470.57-1767.34) , 1: 1854.92 (1715.83-2005.29) and 1: 1625.50 (1452.12-1819.58) , respectively. The pre-booster titer of neutralizing antibody against poliovirus type 1, 2, 3 mainly ranged 1: 128-1: 512, which accounted for 65% (55/84) , 55% (46/84) , 74% (62/84) in each type. After the booster immunization, titers of neutralizing antibody against type 1, 2, 3 were increased as subjects with titer ≥ 1: 1024 accounted for 94% (78/84) , 95% (80/84) , 92% (77/84) , respectively.Safety was evaluated in 96 subjects, of which 16 subjects reported adverse events with the rate of 17%. The observed local

  7. Design and Evaluation of a Clock Multiplexing Circuit for the SSRL Booster Accelerator Timing System - Oral Presentation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Araya, Million

    2015-08-25

    SPEAR3 is a 234 m circular storage ring at SLAC’s synchrotron radiation facility (SSRL) in which a 3 GeV electron beam is stored for user access. Typically the electron beam decays with a time constant of approximately 10hr due to electron lose. In order to replenish the lost electrons, a booster synchrotron is used to accelerate fresh electrons up to 3GeV for injection into SPEAR3. In order to maintain a constant electron beam current of 500mA, the injection process occurs at 5 minute intervals. At these times the booster synchrotron accelerates electrons for injection at a 10Hz rate. A 10Hzmore » 'injection ready' clock pulse train is generated when the booster synchrotron is operating. Between injection intervalswhere the booster is not running and hence the 10 Hz ‘injection ready’ signal is not present-a 10Hz clock is derived from the power line supplied by Pacific Gas and Electric (PG&E) to keep track of the injection timing. For this project I constructed a multiplexing circuit to 'switch' between the booster synchrotron 'injection ready' clock signal and PG&E based clock signal. The circuit uses digital IC components and is capable of making glitch-free transitions between the two clocks. This report details construction of a prototype multiplexing circuit including test results and suggests improvement opportunities for the final design.« less

  8. Design and Evaluation of a Clock Multiplexing Circuit for the SSRL Booster Accelerator Timing System - Final Paper

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Araya, Million

    2015-08-21

    SPEAR3 is a 234 m circular storage ring at SLAC’s synchrotron radiation facility (SSRL) in which a 3 GeV electron beam is stored for user access. Typically the electron beam decays with a time constant of approximately 10hr due to electron lose. In order to replenish the lost electrons, a booster synchrotron is used to accelerate fresh electrons up to 3GeV for injection into SPEAR3. In order to maintain a constant electron beam current of 500mA, the injection process occurs at 5 minute intervals. At these times the booster synchrotron accelerates electrons for injection at a 10Hz rate. A 10Hzmore » 'injection ready' clock pulse train is generated when the booster synchrotron is operating. Between injection intervals-where the booster is not running and hence the 10 Hz ‘injection ready’ signal is not present-a 10Hz clock is derived from the power line supplied by Pacific Gas and Electric (PG&E) to keep track of the injection timing. For this project I constructed a multiplexing circuit to 'switch' between the booster synchrotron 'injection ready' clock signal and PG&E based clock signal. The circuit uses digital IC components and is capable of making glitch-free transitions between the two clocks. This report details construction of a prototype multiplexing circuit including test results and suggests improvement opportunities for the final design.« less

  9. Orion EM-1 Booster Preps - Aft Skirt Preps/Painting

    NASA Image and Video Library

    2016-10-28

    Technicians with Orbital ATK, prime contractor for the Space Launch System (SLS) Booster, prepare the right hand aft skirt for NASA’s SLS rocket for primer and painting inside a support building at the Hangar AF facility at Cape Canaveral Air Force Station in Florida. The space shuttle-era aft skirt, was inspected and resurfaced and will be primed and painted for use on the right hand booster of the SLS rocket for Exploration Mission 1 (EM-1). NASA is preparing for EM-1, deep-space missions, and the journey to Mars.

  10. Orion EM-1 Booster Preps - Aft Skirt Preps/Painting

    NASA Image and Video Library

    2016-10-28

    Technicians with Orbital ATK, prime contractor for the Space Launch System (SLS) Booster, prepare a paint mixture for the right hand aft skirt for NASA’s SLS in a support building at the Hangar AF facility at Cape Canaveral Air Force Station in Florida. The space shuttle-era aft skirt, was inspected and resurfaced, and will be primed and painted for use on the right hand booster of the SLS rocket for Exploration Mission 1 (EM-1). NASA is preparing for EM-1, deep-space missions, and the Journey to Mars.

  11. Debris control design achievements of the booster separation motors

    NASA Technical Reports Server (NTRS)

    Smith, G. W.; Chase, C. A.

    1985-01-01

    The stringent debris control requirements imposed on the design of the Space Shuttle booster separation motor are described along with the verification program implemented to ensure compliance with debris control objectives. The principal areas emphasized in the design and development of the Booster Separation Motor (BSM) relative to debris control were the propellant formulation and nozzle closures which protect the motors from aerodynamic heating and moisture. A description of the motor design requirements, the propellant formulation and verification program, and the nozzle closures design and verification are presented.

  12. Misuse of booster cushions among children and adults in Shanghai-an observational and attitude study during buckling up.

    PubMed

    Bohman, Katarina; Jorlöv, Sofia; Zhou, Shengqi; Zhao, Cloud; Sui, Bo; Ding, Chengkai

    2016-10-02

    Traffic crashes are one of the leading causes of fatalities among Chinese children. Booster cushion usage in China is low, and there are no studies showing how a population with limited experience handles booster cushions during buckling up. The purpose of this study was to evaluate the handling of and explore the attitudes toward booster cushions among children, parents, and grandparents in Shanghai. An observational study including a convenience sample of 254 children aged 4-12 years was conducted in 2 passenger cars at a shopping center in Shanghai. Parents, grandparents, or the children themselves buckled up the child on 2 types of booster cushions, a 2-stage integrated booster cushion (IBC) and an aftermarket booster cushion (BC). The test participants were observed during buckling up, first without and then with instructions. The test leaders conducted structured interviews. Ninety-eight percent of the uninstructed participants failed to buckle up without identified misuse on the aftermarket booster cushion and 31% of those uninstructed on the integrated booster cushion. The majority of misuse was severe, including placing the belt behind the arm and the lap belt routing above the guiding loops. Instruction reduced misuse to 58% (BC) and 12% (IBC), respectively, and, in particular, severe misuse. Some misuse was related to limited knowledge of how to buckle up on the booster cushion, and some misuse was intentional in order to reduce discomfort. The participants, both children and adults, reported that they preferred the IBC due to good comfort and convenience. Safety was reported as the main reason for adults using booster cushions in general, whereas children reported comfort as the most important motivation. Education is needed to ensure frequent and correct use of booster cushions in China and to raise safety awareness among children and adults. Furthermore, it is important that the booster cushions offer intuitively correct usage to a population with

  13. Robust Humoral and Cellular Immune Responses to Pertussis in Adults After a First Acellular Booster Vaccination.

    PubMed

    van der Lee, Saskia; van Rooijen, Debbie M; de Zeeuw-Brouwer, Mary-Lène; Bogaard, Marjan J M; van Gageldonk, Pieter G M; Marinovic, Axel Bonacic; Sanders, Elisabeth A M; Berbers, Guy A M; Buisman, Anne-Marie

    2018-01-01

    To reduce the pertussis disease burden, nowadays several countries recommend acellular pertussis (aP) booster vaccinations for adults. We aimed to evaluate the immunogenicity of a first adult aP booster vaccination at childbearing age. In 2014, healthy adults aged 25-29 years ( n  = 105), vaccinated during infancy with four doses of whole-cell pertussis (wP) vaccine, received a Tdap (tetanus, diphtheria, and aP) booster vaccination. Blood samples were collected longitudinally pre-booster, 2 and 4 weeks, and 1 year and 2 years post-booster. Tdap vaccine antigen-specific antibody levels and memory B- and T-cell responses were determined at all time points. Antibody persistence was calculated using a bi-exponential decay model. Upon booster vaccination, the IgG levels specific to all Tdap vaccine antigens were significantly increased. After an initial rapid decline in the first year, PT-IgG antibody decay was limited (15%) in the second year post-booster. The duration of a median level of PT-IgG ≥20 IU/mL was estimated to be approximately 9 years. Vaccine antigen-specific memory B- and T-cell numbers increased and remained at high levels although a significant decline was observed after 4 weeks post-booster. However, Th1, Th2, and Th17 cytokine production remained above pre-booster levels for 2 years. The Tdap booster vaccination in wP-primed Dutch adults induced robust long-term humoral and cellular immune responses to pertussis antigens. Furthermore, PT-IgG levels are predicted to remain above the presumed protective cut-off for at least 9 years which might deserves further attention in evaluating the current recommendation to revaccinate women during every new pregnancy.

  14. Identifying information that promotes belt-positioning booster use. Volume 1, Summary and findings

    DOT National Transportation Integrated Search

    2008-07-01

    Many parents with low educational attainment prematurely graduate their children to seat belt restraint rather than use belt-positioning booster seats. This study aimed to identify interventions that promoted booster seat use among this population. F...

  15. Longitudinal emittance measurements in the Booster and AGS during the 2014 RHIC gold run

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zeno, K.

    2014-08-18

    This note describes longitudinal emittance measurements that were made in the Booster and AGS during the 2014 RHIC Gold run. It also contains an overview of the longitudinal aspects of their setup during this run. Each bunch intended for RHIC is composed of beam from 4 Booster cycles, and there are two of them per AGS cycle. For each of the 8 Booster cycles required to produce the 2 bunches in the AGS, a beam pulse from EVIS is injected into the Booster and captured in four h=4 buckets. Then those bunches are accelerated to a porch where they aremore » merged into 2 bunches and then into 1 bunch.« less

  16. Officials Stand Before Mercury-Redstone Booster

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This photograph shows a group of officials standing before a Mercury-Redstone booster at the Marshall Space Flight Center (MSFC). Among those in the photograph are astronauts James Lovell, Walter Schirra, and Gus Grissom. Also pictured is Joachim Kuettner who managed responsibilities of MSFC's Mercury-Redstone program.

  17. 30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

  18. 30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

  19. 30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

  20. 30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

  1. Power-Amplifier Module for 145 to 165 GHz

    NASA Technical Reports Server (NTRS)

    Samoska, Lorene; Peralta, Alejandro

    2007-01-01

    A power-amplifier module that operates in the frequency range of 145 to 165 GHz has been designed and constructed as a combination of (1) a previously developed monolithic microwave integrated circuit (MMIC) power amplifier and (2) a waveguide module. The amplifier chip was needed for driving a high-electron-mobility-transistor (HEMT) frequency doubler. While it was feasible to connect the amplifier and frequency-doubler chips by use of wire bonds, it was found to be much more convenient to test the amplifier and doubler chips separately. To facilitate separate testing, it was decided to package the amplifier and doubler chips in separate waveguide modules. Figure 1 shows the resulting amplifier module. The amplifier chip was described in "MMIC HEMT Power Amplifier for 140 to 170 GHz" (NPO-30127), NASA Tech Briefs, Vol. 27, No. 11, (November 2003), page 49. To recapitulate: This is a three-stage MMIC power amplifier that utilizes HEMTs as gain elements. The amplifier was originally designed to operate in the frequency range of 140 to 170 GHz. The waveguide module is based on a previously developed lower frequency module, redesigned to support operation in the frequency range of 140 to 220 GHz. Figure 2 presents results of one of several tests of the amplifier module - measurements of output power and gain as functions of input power at an output frequency of 150 GHz. Such an amplifier module has many applications to test equipment for power sources above 100 GHz.

  2. OCO-2 1st Stage Booster Preps

    NASA Image and Video Library

    2014-03-21

    VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, rests on a transportation cradle in the Horizontal Integration Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  3. OCO-2 1st Stage Booster Preps

    NASA Image and Video Library

    2014-03-21

    VANDENBERG AIR FORCE BASE, Calif. – A worker in the Horizontal Integration Facility inspects the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, before its move to Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  4. OCO-2 1st Stage Booster Preps

    NASA Image and Video Library

    2014-03-21

    VANDENBERG AIR FORCE BASE, Calif. – A tethered worker in the Horizontal Integration Facility prepares the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, for its move to Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  5. Auto-Zero Differential Amplifier

    NASA Technical Reports Server (NTRS)

    Quilligan, Gerard T. (Inventor); Aslam, Shahid (Inventor)

    2017-01-01

    An autozero amplifier may include a window comparator network to monitor an output offset of a differential amplifier. The autozero amplifier may also include an integrator to receive a signal from a latched window comparator network, and send an adjustment signal back to the differential amplifier to reduce an offset of the differential amplifier.

  6. Tailored interventions for screening mammography among a sample of initially non-adherent women: when is a booster dose important?

    PubMed

    Skinner, Celette Sugg; Kobrin, Sarah C; Monahan, Patrick O; Daggy, Joanne; Menon, Usha; Todora, Helen Smith; Champion, Victoria L

    2007-01-01

    To assess added value of a booster dose of a tailored mammography intervention. Participants, non-adherent at baseline, were randomly assigned to usual care or one of three tailored interventions. Intervention group members (n=657) were further randomly assigned to receive/not receive a booster intervention dose. Electronic record mammography data were collected following initial intervention and at 6 and 15 months post-booster. Booster had no effect among women not screened after first intervention dose (n=337). Among women screened after initial dose (n=320), booster predicted re-screening at 6 but not 15 months. A boosterxrace interaction showed a booster effect at 6 months for African Americans (OR=4.66, p=.0005) but not Caucasians (OR=0.74, p=.44). Findings suggest if a first-dose intervention does not facilitate screening, neither will a booster dose. However, among women for whom a first dose is effective, boosters can facilitate timely repeat adherence, especially among African Americans. At 6 months booster recipients were less likely to be off-schedule but, by 15 months, the groups were similar. Boosters may effect when, but not whether, women continue screening.

  7. Ferroelectric Field-Effect Transistor Differential Amplifier Circuit Analysis

    NASA Technical Reports Server (NTRS)

    Phillips, Thomas A.; MacLeod, Todd C.; Ho, Fat D.

    2008-01-01

    There has been considerable research investigating the Ferroelectric Field-Effect Transistor (FeFET) in memory circuits. However, very little research has been performed in applying the FeFET to analog circuits. This paper investigates the use of FeFETs in a common analog circuit, the differential amplifier. The two input Metal-Oxide-Semiconductor (MOS) transistors in a general MOS differential amplifier circuit are replaced with FeFETs. Resistors are used in place of the other three MOS transistors. The FeFET model used in the analysis has been previously reported and was based on experimental device data. Because of the FeFET hysteresis, the FeFET differential amplifier has four different operating modes depending on whether the FeFETs are positively or negatively polarized. The FeFET differential amplifier operation in the different modes was analyzed by calculating the amplifier voltage transfer and gain characteristics shown in figures 2 through 5. Comparisons were made between the FeFET differential amplifier and the standard MOS differential amplifier. Possible applications and benefits of the FeFET differential amplifier are discussed.

  8. Fred Hutchinson Cancer Research Center (FHCRC-1): Functional Exploration of the Druggable Genome in MYCN Amplified and Non-amplified Neuroblastoma | Office of Cancer Genomics

    Cancer.gov

    To identify candidate drugs targets for neuroblastoma with MYCN amplification we performed parallel siRNA screens with a druggable genome collection of ~6,700 genes comparing MYCN amplified and non-MYCN amplified cell lines: SK-N-BE2 (MYCN amplified) and SK-N-AS (non amplified).  The Hits from each cell lines were determined based on their significance with respect to their differential activity in the presence or absence of RA within each cell line.  Hits for each cell line were also ranked according to their P-value, based on the three replicates.  Integration with gene exp

  9. Fred Hutchinson Cancer Research Center (FHCRC-1): Functional Exploration of the Druggable Genome in MYCN Amplified and Non-amplified Neuroblastoma | Office of Cancer Genomics

    Cancer.gov

    To identify candidate drugs targets for neuroblastoma with MYCN amplification we performed parallel siRNA screens with a druggable genome collection of ~6,700 genes comparing MYCN amplified and non-MYCN amplified cell lines: SK-N-BE2 (MYCN amplified) and SK-N-AS (non amplified). The Hits from each cell lines were determined based on their significance with respect to their differential activity in the presence or absence of RA within each cell line. Hits for each cell line were also ranked according to their P-value, based on the three replicates. Integration with gene expres

  10. Sensitivity Enhancement of an Inductively Coupled Local Detector Using a HEMT-based Current Amplifier

    PubMed Central

    Qian, Chunqi; Duan, Qi; Dodd, Steve; Koretsky, Alan; Murphy-Boesch, Joe

    2015-01-01

    Purpose To improve the signal transmission efficiency and sensitivity of a local detection coil that is weakly inductively coupled to a larger receive coil. Methods The resonant detection coil is connected in parallel with the gate of a HEMT transistor without impedance matching. When the drain of the transistor is capacitively shunted to ground, current amplification occurs in the resonator by feedback that transforms a capacitive impedance on the transistor’s source to a negative resistance on its gate. Results High resolution images were obtained from a mouse brain using a small, 11 mm diameter surface coil that was inductively coupled to a commercial, phased array chest coil. Although the power consumption of the amplifier was only 88 µW, 14 dB gain was obtained with excellent noise performance. Conclusion An integrated current amplifier based on a High Electron Mobility Transistor (HEMT) can enhance the sensitivity of inductively coupled local detectors when weakly coupled. This amplifier enables efficient signal transmission between customized user coils and commercial clinical coils, without the need for a specialized signal interface. PMID:26192998

  11. 47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

  12. 47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) Interference to the direct... continue to operate if an FM translator or FM booster station demonstrates that the LPFM station is causing...

  13. 47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

  14. 47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) Interference to the direct... authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster...

  15. 47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

  16. Optics Corrections with LOCO in the Fermilab Booster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tan, Cheng-Yang; Prost, Lionel; Seiya, Kiyomi

    2016-06-01

    The optics of the Fermilab Booster has been corrected with LOCO (Linear Optics from Closed Orbits). However, the first corrections did not show any improvement in capture efficiency at injection. A detailed analysis of the results showed that the problem lay in the MADX optics file. Both the quadrupole and chromatic strengths were originally set as constants independent of beam energy. However, careful comparison between the measured and calculated tunes and chromatcity show that these strengths are energy dependent. After the MADX model was modified with these new energy dependent strengths, the LOCO corrected lattice has been applied to Booster.more » The effect of the corrected lattice will be discussed here.« less

  17. A multichannel EEG acquisition scheme based on single ended amplifiers and digital DRL.

    PubMed

    Haberman, Marcelo Alejandro; Spinelli, Enrique Mario

    2012-12-01

    Single ended (SE) amplifiers allow implementing biopotential front-ends with a reduced number of parts, being well suited for preamplified electrodes or compact EEG headboxes. On the other hand, given that each channel has independent gain; mismatching between these gains results in poor common-mode rejection ratios (CMRRs) (about 30 dB considering 1% tolerance components). This work proposes a scheme for multichannel EEG acquisition systems based on SE amplifiers and a novel digital driven right leg (DDRL) circuit, which overcome the poor CMRR of the front-end stage providing a high common mode reduction at power line frequency (up to 80 dB). A functional prototype was built and tested showing the feasibility of the proposed technique. It provided EEG records with negligible power line interference, even in very aggressive EMI environments.

  18. Low noise tuned amplifier

    NASA Technical Reports Server (NTRS)

    Kleinberg, L. L. (Inventor)

    1984-01-01

    A bandpass amplifier employing a field effect transistor amplifier first stage is described with a resistive load either a.c. or directly coupled to the non-inverting input of an operational amplifier second stage which is loaded in a Wien Bridge configuration. The bandpass amplifier may be operated with a signal injected into the gate terminal of the field effect transistor and the signal output taken from the output terminal of the operational amplifier. The operational amplifier stage appears as an inductive reactance, capacitive reactance and negative resistance at the non-inverting input of the operational amplifier, all of which appear in parallel with the resistive load of the field effect transistor.

  19. Reusable Boosters in a European-Russian Perspective

    NASA Astrophysics Data System (ADS)

    Deneu, François; Ramiandrasoa, Fabienne

    2002-01-01

    In 2001, EADS and Khrunichev SRPSC have initiated and carried out a working group devoted to the analysis of potential common studies and developments in the field of space activities. This working group came up with several propositions of interest, among which, the use of reusable boosters issued from Khrunichev previous design appeared to be promising when applied to heavy type launchers. Although the results required to be confirmed by detailed studies prior to final conclusions, preliminary studies have shown the interest of Ariane 5 configurations using such reusable booster in view of reducing the specific and launch cost as well as potentially increasing the performance. In November 2001, EADS and KHRUNICHEV SRPSC have started a study on an Ariane 5 plus reusable boosters configuration. This study aims at obtaining a better understanding of the advantages and drawbacks attached to such a use. Technical feasibility is more in depth analysed, with all recurring and not recurring aspects (including launch infrastructure modifications). Programmatic aspects are also addressed in order to better assess potential economic advantages and unavoidable drawbacks. Beyond that the identification of what could be, for western Europe and Russian players, an efficient and pay- off industrial organisation, is also a study theme of importance. This papers intends to present the main results achieved within this study and the propositions for the future which are likely to provide western Europe and Russia with stronger positions in the competitive field of launch business.

  20. Multi-Physics Analysis of the Fermilab Booster RF Cavity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Awida, M.; Reid, J.; Yakovlev, V.

    After about 40 years of operation the RF accelerating cavities in Fermilab Booster need an upgrade to improve their reliability and to increase the repetition rate in order to support a future experimental program. An increase in the repetitio n rate from 7 to 15 Hz entails increasing the power dissipation in the RF cavities, their ferrite loaded tuners, and HOM dampers. The increased duty factor requires careful modelling for the RF heating effects in the cavity. A multi-physic analysis invest igating both the RF and thermal properties of Booster cavity under various operating conditions is presented in this paper.

  1. Multi-Physics Analysis of the Fermilab Booster RF Cavity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Awida, M.; Reid, J.; Yakovlev, V.

    After about 40 years of operation the RF accelerating cavities in Fermilab Booster need an upgrade to improve their reliability and to increase the repetition rate in order to support a future experimental program. An increase in the repetition rate from 7 to 15 Hz entails increasing the power dissipation in the RF cavities, their ferrite loaded tuners, and HOM dampers. The increased duty factor requires careful modelling for the RF heating effects in the cavity. A multi-physic analysis investigating both the RF and thermal properties of Booster cavity under various operating conditions is presented in this paper.

  2. Orion EM-1 Booster Preps - Aft Skirt Preps/Painting

    NASA Image and Video Library

    2016-10-28

    A paint technician with Orbital ATK, prime contractor for the Space Launch System (SLS) Booster, uses an air gun to apply paint to the right hand aft skirt for NASA’s SLS rocket inside a support building at the Hangar AF facility at Cape Canaveral Air Force Station. The space shuttle-era aft skirt, was inspected and resurfaced to prepare it for primer and paint. The aft skirt will be used on the right hand booster of the SLS rocket for Exploration Mission 1 (EM-1). NASA is preparing for EM-1, deep-space missions, and the journey to Mars.

  3. A new one-man submarine is tested as vehicle for solid rocket booster retrieval

    NASA Technical Reports Server (NTRS)

    2000-01-01

    A mockup of a solid rocket booster nozzle is lowered into the waters of the Atlantic during a test of a new booster retrieval method. A one-man submarine known as DeepWorker 2000 is being tested on its ability to duplicate the sometimes hazardous job United Space Alliance (USA) divers perform to recover the expended boosters in the ocean after a launch. The boosters splash down in an impact area about 140 miles east of Jacksonville and after recovery are towed back to KSC for refurbishment by the specially rigged recovery ships. DeepWorker 2000 will be used in a demonstration during retrieval operations after the upcoming STS-101 launch. The submarine pilot will demonstrate capabilities to cut tangled parachute riser lines using a manipulator arm and attach a Diver Operator Plug to extract water and provide flotation for the booster. DeepWorker 2000 was built by Nuytco Research Ltd., North Vancouver, British Columbia. It is 8.25 feet long, 5.75 feet high, and weighs 3,800 pounds. USA is a prime contractor to NASA for the Space Shuttle program.

  4. Amplify-and-forward cooperative diversity for green UWB-based WBSNs.

    PubMed

    Shaban, Heba; Abou El-Nasr, Mohamad

    2013-01-01

    This paper proposes a novel green cooperative diversity technique based on suboptimal template-based ultra-wideband (UWB) wireless body sensor networks (WBSNs) using amplify-and-forward (AF) relays. In addition, it analyzes the bit-error-rate (BER) performance of the proposed nodes. The analysis is based on the moment-generating function (MGF) of the total signal-to-noise ratio (SNR) at the destination. It also provides an approximate value for the total SNR. The analysis studies the performance of equally correlated binary pulse position modulation (EC-BPPM) assuming the sinusoidal and square suboptimal template pulses. Numerical results are provided for the performance evaluation of optimal and suboptimal template-based nodes with and without relay cooperation. Results show that one relay node provides ~23 dB performance enhancement at 1e - 3 BER, which mitigates the effect of the nondesirable non-line-of-sight (NLOS) links in WBSNs.

  5. Amplify-and-Forward Cooperative Diversity for Green UWB-Based WBSNs

    PubMed Central

    2013-01-01

    This paper proposes a novel green cooperative diversity technique based on suboptimal template-based ultra-wideband (UWB) wireless body sensor networks (WBSNs) using amplify-and-forward (AF) relays. In addition, it analyzes the bit-error-rate (BER) performance of the proposed nodes. The analysis is based on the moment-generating function (MGF) of the total signal-to-noise ratio (SNR) at the destination. It also provides an approximate value for the total SNR. The analysis studies the performance of equally correlated binary pulse position modulation (EC-BPPM) assuming the sinusoidal and square suboptimal template pulses. Numerical results are provided for the performance evaluation of optimal and suboptimal template-based nodes with and without relay cooperation. Results show that one relay node provides ~23 dB performance enhancement at 1e − 3 BER, which mitigates the effect of the nondesirable non-line-of-sight (NLOS) links in WBSNs. PMID:24307880

  6. Solid rocket booster internal flow analysis by highly accurate adaptive computational methods

    NASA Technical Reports Server (NTRS)

    Huang, C. Y.; Tworzydlo, W.; Oden, J. T.; Bass, J. M.; Cullen, C.; Vadaketh, S.

    1991-01-01

    The primary objective of this project was to develop an adaptive finite element flow solver for simulating internal flows in the solid rocket booster. Described here is a unique flow simulator code for analyzing highly complex flow phenomena in the solid rocket booster. New methodologies and features incorporated into this analysis tool are described.

  7. Portable musical instrument amplifier

    DOEpatents

    Christian, David E.

    1990-07-24

    The present invention relates to a musical instrument amplifier which is particularly useful for electric guitars. The amplifier has a rigid body for housing both the electronic system for amplifying and processing signals from the guitar and the system's power supply. An input plug connected to and projecting from the body is electrically coupled to the signal amplifying and processing system. When the plug is inserted into an output jack for an electric guitar, the body is rigidly carried by the guitar, and the guitar is operatively connected to the electrical amplifying and signal processing system without use of a loose interconnection cable. The amplifier is provided with an output jack, into which headphones are plugged to receive amplified signals from the guitar. By eliminating the conventional interconnection cable, the amplifier of the present invention can be used by musicians with increased flexibility and greater freedom of movement.

  8. Environmentally friendly procedure based on VA-MSPD for the determination of booster biocides in fish tissue.

    PubMed

    Vieira, Augusto A; Caldas, Sergiane S; Escarrone, Ana Laura Venquiaruti; Arias, Jean Lucas de Oliveira; Primel, Ednei Gilberto

    2018-03-01

    Booster biocides have been widely applied to ships and other submerged structures. These compounds can be released into the marine environment as the result of vessel hull leaching and may remain in different environmental compartments. This study aimed at introducing an environmentally friendly procedure for the extraction of irgarol and diuron from fish samples by vortex-assisted matrix solid phase dispersion (VA-MSPD) with detection by liquid chromatography tandem mass spectrometry. Different types of solid supports and solvents were evaluated. The best results were found when 0.5g mussel shell, 0.5g sodium sulfate and 5mL ethanol were used. Analytical recoveries ranged from 81 to 110%, with RSD below 10%, whereas the matrix effect was between -17 and 1% (for all samples under study). LOQ values of irgarol and diuron were 5 and 50ngg -1 , respectively. The method under investigation proved to be a promising alternative to controlling contamination of fish by booster biocides, with low consumption of biodegradable reagents. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Aerodynamic stability and control characteristics of TBC shuttle booster AR-11981-3

    NASA Technical Reports Server (NTRS)

    Phelps, E. R.; Watts, L. L.; Ainsworth, R. W.

    1972-01-01

    A scale model of the Boeing Company space shuttle booster configuration 3 was tested in the MSFC 14-inch trisonic wind tunnel. This test was proposed to fill-in the original test run schedule as well as to investigate the aerodynamic stability and control characteristics of the booster with three wing configurations not previously tested. The configurations tested included: (1) a cylindrical booster body with an axisymmetric nose, (2) clipped delta canards that had variable incidence from 0 deg to -60 deg, (3) different aft body mounted wing configurations, (4) two vertical fin configurations, and (5) a Grumman G-3 orbiter configuration. Tests were conducted over a Mach range from 0.6 to 5.0.

  10. Study of solid rocket motors for a space shuttle booster. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The design, development, production, and launch support analysis for determining the solid propellant rocket engine to be used with the space shuttle are discussed. Specific program objectives considered were: (1) definition of engine designs to satisfy the performance and configuration requirements of the various vehicle/booster concepts, (2) definition of requirements to produce booster stages at rates of 60, 40, 20, and 10 launches per year in a man-rated system, and (3) estimation of costs for the defined SRM booster stages.

  11. 78 FR 55648 - Signal Booster Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Parts 1, 20, 22, 24, 27, and 90 [WT Docket No. 10-4; FCC 13-21] Signal Booster Rules AGENCY: Federal Communications Commission. ACTION: Final rule... information is contained in Sections 4(i), 303(g), 303(r), and 332(a) of the Communications Act of 1934, as...

  12. High-Efficiency Microwave Power Amplifier

    NASA Technical Reports Server (NTRS)

    Sims, Williams H.

    2005-01-01

    A high-efficiency power amplifier that operates in the S band (frequencies of the order of a few gigahertz) utilizes transistors operating under class-D bias and excitation conditions. Class-D operation has been utilized at lower frequencies, but, until now, has not been exploited in the S band. Nominally, in class D operation, a transistor is switched rapidly between "on" and "off" states so that at any given instant, it sustains either high current or high voltage, but not both at the same time. In the ideal case of zero "on" resistance, infinite "off" resistance, zero inductance and capacitance, and perfect switching, the output signal would be a perfect square wave. Relative to the traditional classes A, B, and C of amplifier operation, class D offers the potential to achieve greater power efficiency. In addition, relative to class-A amplifiers, class-D amplifiers are less likely to go into oscillation. In order to design this amplifier, it was necessary to derive mathematical models of microwave power transistors for incorporation into a larger mathematical model for computational simulation of the operation of a class-D microwave amplifier. The design incorporates state-of-the-art switching techniques applicable only in the microwave frequency range. Another major novel feature is a transmission-line power splitter/combiner designed with the help of phasing techniques to enable an approximation of a square-wave signal (which is inherently a wideband signal) to propagate through what would, if designed in a more traditional manner, behave as a more severely band-limited device (see figure). The amplifier includes an input, a driver, and a final stage. Each stage contains a pair of GaAs-based field-effect transistors biased in class D. The input signal can range from -10 to +10 dBm into a 50-ohm load. The table summarizes the performances of the three stages

  13. ION BEAM POLARIZATION DYNAMICS IN THE 8 GEV BOOSTER OF THE JLEIC PROJECT AT JLAB

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kondratenko, A. M.; Kondratenko, M. A.; Morozov, Vasiliy

    2016-05-01

    In the Jefferson Lab’s Electron-Ion Collider (JLEIC) project, an injector of polarized ions into the collider ring is a superconducting 8 GeV booster. Both figure-8 and racetrack booster versions were considered. Our analysis showed that the figure-8 ring configuration allows one to preserve the polarization of any ion species during beam acceleration using only small longitudinal field with an integral less than 0.5 Tm. In the racetrack booster, to pre-serve the polarization of ions with the exception of deu-terons, it suffices to use a solenoidal Siberian snake with a maximum field integral of 30 Tm. To preserve deuteron polarization, wemore » propose to use arc magnets for the race-track booster structure with a field ramp rate of the order of 1 T/s. We calculate deuteron and proton beam polari-zations in both the figure-8 and racetrack boosters includ-ing alignment errors of their magnetic elements using the Zgoubi code.« less

  14. High-gain cryogenic amplifier assembly employing a commercial CMOS operational amplifier.

    PubMed

    Proctor, J E; Smith, A W; Jung, T M; Woods, S I

    2015-07-01

    We have developed a cryogenic amplifier for the measurement of small current signals (10 fA-100 nA) from cryogenic optical detectors. Typically operated with gain near 10(7) V/A, the amplifier performs well from DC to greater than 30 kHz and exhibits noise level near the Johnson limit. Care has been taken in the design and materials to control heat flow and temperatures throughout the entire detector-amplifier assembly. A simple one-board version of the amplifier assembly dissipates 8 mW to our detector cryostat cold stage, and a two-board version can dissipate as little as 17 μW to the detector cold stage. With current noise baseline of about 10 fA/(Hz)(1/2), the cryogenic amplifier is generally useful for cooled infrared detectors, and using blocked impurity band detectors operated at 10 K, the amplifier enables noise power levels of 2.5 fW/(Hz)(1/2) for detection of optical wavelengths near 10 μm.

  15. Space shuttle solid rocket booster recovery system definition, volume 1

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The performance requirements, preliminary designs, and development program plans for an airborne recovery system for the space shuttle solid rocket booster are discussed. The analyses performed during the study phase of the program are presented. The basic considerations which established the system configuration are defined. A Monte Carlo statistical technique using random sampling of the probability distribution for the critical water impact parameters was used to determine the failure probability of each solid rocket booster component as functions of impact velocity and component strength capability.

  16. OCO-2 1st Stage Booster Preps

    NASA Image and Video Library

    2014-03-21

    VANDENBERG AIR FORCE BASE, Calif. – A technician working inside the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, completes final tasks in preparation for its move from the Horizontal Integration Facility to Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

  17. Achieving Space Shuttle Abort-to-Orbit Using the Five-Segment Booster

    NASA Technical Reports Server (NTRS)

    Craft, Joe; Ess, Robert; Sauvageau, Don

    2003-01-01

    The Five-Segment Booster design concept was evaluated by a team that determined the concept to be feasible and capable of achieving the desired abort-to-orbit capability when used in conjunction with increased Space Shuttle main engine throttle capability. The team (NASA Johnson Space Center, NASA Marshall Space Flight Center, ATK Thiokol Propulsion, United Space Alliance, Lockheed-Martin Space Systems, and Boeing) selected the concept that provided abort-to-orbit capability while: 1) minimizing Shuttle system impacts by maintaining the current interface requirements with the orbiter, external tank, and ground operation systems; 2) minimizing changes to the flight-proven design, materials, and processes of the current four-segment Shuttle booster; 3) maximizing use of existing booster hardware; and 4) taking advantage of demonstrated Shuttle main engine throttle capability. The added capability can also provide Shuttle mission planning flexibility. Additional performance could be used to: enable implementation of more desirable Shuttle safety improvements like crew escape, while maintaining current payload capability; compensate for off nominal performance in no-fail missions; and support missions to high altitudes and inclinations. This concept is a low-cost, low-risk approach to meeting Shuttle safety upgrade objectives. The Five-Segment Booster also has the potential to support future heavy-lift missions.

  18. Fermilab Booster Transition Crossing Simulations and Beam Studies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhat, C. M.; Tan, C. Y.

    2016-01-01

    The Fermilab Booster accelerates beam from 400 MeV to 8 GeV at 15 Hz. In the PIP (Proton Improvement Plan) era, it is required that Booster deliver 4.2 xmore » $$10^{12}$$ protons per pulse to extraction. One of the obstacles for providing quality beam to the users is the longitudinal quadrupole oscillation that the beam suffers from right after transition. Although this oscillation is well taken care of with quadrupole dampers, it is important to understand the source of these oscillations in light of the PIP II requirements that require 6.5 x $$10^{12}$$ protons per pulse at extraction. This paper explores the results from machine studies, computer simulations and solutions to prevent the quadrupole oscillations after transition.« less

  19. Aerodynamic characteristics of a 142-inch diameter solid rocket booster, configuration 139 (SA2FA/SA2FB)

    NASA Technical Reports Server (NTRS)

    Radford, W. D.; Johnson, J. D.

    1974-01-01

    Tests of a 2.112 percent scale model of the space shuttle solid rocket booster model were conducted in a transonic pressure tunnel. Tests were conducted at Mach numbers ranging from 0.4 to 1.2, angles of attack from minus one degree to plus 181 degrees, and Reynolds numbers from 0.6 million to 6.1 million per foot. The model configurations investigated were as follows: (1) solid rocket booster without external protuberances, (2) solid rocket booster with an electrical tunnel and a solid rocket booster/external tank thrust attachment structure, and (3) solid rocket booster with two body strakes.

  20. [Safety and immunogenicity of a 7-valent pneumococcal conjugate vaccine (Prevenar) booster dose in healthy Chinese toddlers].

    PubMed

    Li, Rong-cheng; Li, Feng-xiang; Li, Yan-ping

    2009-06-01

    To evaluate the safety and immunogenicity of the booster dose of 7 valent pneumococcal conjugate vaccine (PCV7) to the healthy Chinese toddlers who had received 3 primary doses. Four hundred and eighty-eight Chinese toddlers received a booster dose of PCV7 at age of 12-15 months following a primary series of the vaccine given at ages 3, 4, 5 months separately with Diphtheria Tetanus Acellular Pertussis Combined Vaccine (DTaP) in Group 1 or concurrently with DTaP in Group 2. Following the booster dose immunization, each subject was followed up for 30 days to observe the safety of the vaccine. Blood samples were taken from a subset of subjects prior and post 30 days the booster dose immunization to evaluate immunogenicity. A high proportion of subjects in Group 1 (89%) and Group 2 (91%) remained afebrile after the booster dose. Local reactions to the PCV7 booster dose were generally mild. For each serotype, the rise in GMC (post-/pre-vaccination) showed a statistically significant difference (P<0.0001) between both groups. PCV7 administered as a booster dose is generally safe, well tolerate, and immunogenic in healthy Chinese toddlers.

  1. TDRS-M Atlas V Booster and Centaur Stages Offload, Booster Trans

    NASA Image and Video Library

    2017-06-27

    A United Launch Alliance Atlas V rocket booster arrives at the Atlas Spaceflight Operations Center at Cape Canaveral Air Force Station in Florida. The rocket is scheduled to launch the Tracking and Data Relay Satellite, TDRS-M. It will be the latest spacecraft destined for the agency's constellation of communications satellites that allows nearly continuous contact with orbiting spacecraft ranging from the International Space Station and Hubble Space Telescope to the array of scientific observatories. Liftoff atop the ULA Atlas V rocket is scheduled to take place from Cape Canaveral's Space Launch Complex 41 on Aug. 3, 2017 at 9:02 a.m. EDT.

  2. TDRS-M Atlas V Booster and Centaur Stages Offload, Booster Trans

    NASA Image and Video Library

    2017-06-27

    A United Launch Alliance Atlas V rocket booster is transported to the Atlas Spaceflight Operations Center at Cape Canaveral Air Force Station in Florida. The rocket is scheduled to launch the Tracking and Data Relay Satellite, TDRS-M. It will be the latest spacecraft destined for the agency's constellation of communications satellites that allows nearly continuous contact with orbiting spacecraft ranging from the International Space Station and Hubble Space Telescope to the array of scientific observatories. Liftoff atop the ULA Atlas V rocket is scheduled to take place from Cape Canaveral's Space Launch Complex 41 on Aug. 3, 2017 at 9:02 a.m. EDT.

  3. TDRS-M Atlas V Booster and Centaur Stages Offload, Booster Trans

    NASA Image and Video Library

    2017-06-27

    The United Launch Alliance (ULA) Mariner arrives at Port Canaveral in Florida carrying an Atlas V rocket booster bound for nearby Cape Canaveral Air Force Station. The rocket is scheduled to launch the Tracking and Data Relay Satellite, TDRS-M. It will be the latest spacecraft destined for the agency's constellation of communications satellites that allows nearly continuous contact with orbiting spacecraft ranging from the International Space Station and Hubble Space Telescope to the array of scientific observatories. Liftoff atop the ULA Atlas V rocket is scheduled to take place from Cape Canaveral's Space Launch Complex 41 on Aug. 3, 2017 at 9:02 a.m. EDT.

  4. Towards a THz backward wave amplifier in European OPTHER project

    NASA Astrophysics Data System (ADS)

    Dispenza, M.; Brunetti, F.; Cojocaru, C.-S.; de Rossi, A.; Di Carlo, A.; Dolfi, D.; Durand, A.; Fiorello, A. M.; Gohier, A.; Guiset, P.; Kotiranta, M.; Krozer, V.; Legagneux, P.; Marchesin, R.; Megtert, S.; Bouamrane, F.; Mineo, M.; Paoloni, C.; Pham, K.; Schnell, J. P.; Secchi, A.; Tamburri, E.; Terranova, M. L.; Ulisse, G.; Zhurbenko, V.

    2010-10-01

    Within the EC funded international project OPTHER (OPtically Driven TeraHertz AmplifiERs) a considerable technological effort is being undertaken, in terms of technological development, THz device design and integration. The ultimate goal is to develop a miniaturised THz amplifier based on vacuum-tube principles The main target specifications of the OPTHER amplifier are the following: - Operating frequency: in the band 0.3 to 2 THz - Output power: > 10 mW ( 10 dBm ) - Gain: 10 to 20 dB. The project is in the middle of its duration. Design and simulations have shown that these targets can be met with a proper device configuration and careful optimization of the different parts of the amplifier. Two parallel schemes will be employed for amplifier realisation: THz Drive Signal Amplifier and Optically Modulated Beam THz Amplifier.

  5. Space transportation booster engine configuration study. Volume 2: Design definition document and environmental analysis

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The objective of the Space Transportation Booster Engine (STBE) Configuration Study is to contribute to the Advanced Launch System (ALS) development effort by providing highly reliable, low cost booster engine concepts for both expendable and reusable rocket engines. The objectives of the space Transportation Booster Engine (STBE) Configuration Study were: (1) to identify engine configurations which enhance vehicle performance and provide operational flexibility at low cost, and (2) to explore innovative approaches to the follow-on Full-Scale Development (FSD) phase for the STBE.

  6. Experimental implementation of a nonlinear beamsplitter based on a phase-sensitive parametric amplifier

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fang, Yami; Feng, Jingliang; Cao, Leiming

    2016-03-28

    Beamsplitters have played an important role in quantum optics experiments. They are often used to split and combine two beams, especially in the construct of an interferometer. In this letter, we experimentally implement a nonlinear beamsplitter using a phase-sensitive parametric amplifier, which is based on four-wave mixing in hot rubidium vapor. Here we show that, despite the different frequencies of the two input beams, the output ports of the nonlinear beamsplitter exhibit interference phenomena. We make measurements of the interference fringe visibility and study how various parameters, such as the intensity gain of the amplifier, the intensity ratio of themore » two input beams, and the one and two photon detunings, affect the behavior of the nonlinear beamsplitter. It may find potential applications in quantum metrology and quantum information processing.« less

  7. What A Booster Club Can Do.

    ERIC Educational Resources Information Center

    Hidinger, George

    This speech was presented at the 1976 American Alliance for Health, Physical Education, and Recreation national convention by the principal of an Iowa high school. It discusses the development and effectiveness of the Jefferson High School Booster Club which was developed by an interested parent and has been quite successful. The club has assisted…

  8. Josephson junction microwave amplifier in self-organized noise compression mode

    PubMed Central

    Lähteenmäki, Pasi; Vesterinen, Visa; Hassel, Juha; Seppä, Heikki; Hakonen, Pertti

    2012-01-01

    The fundamental noise limit of a phase-preserving amplifier at frequency is the standard quantum limit . In the microwave range, the best candidates have been amplifiers based on superconducting quantum interference devices (reaching the noise temperature at 700 MHz), and non-degenerate parametric amplifiers (reaching noise levels close to the quantum limit at 8 GHz). We introduce a new type of an amplifier based on the negative resistance of a selectively damped Josephson junction. Noise performance of our amplifier is limited by mixing of quantum noise from Josephson oscillation regime down to the signal frequency. Measurements yield nearly quantum-limited operation, at 2.8 GHz, owing to self-organization of the working point. Simulations describe the characteristics of our device well and indicate potential for wide bandwidth operation. PMID:22355788

  9. High stability amplifier

    NASA Technical Reports Server (NTRS)

    Adams, W. A.; Reinhardt, V. S. (Inventor)

    1983-01-01

    An electrical RF signal amplifier for providing high temperature stability and RF isolation and comprised of an integrated circuit voltage regulator, a single transistor, and an integrated circuit operational amplifier mounted on a circuit board such that passive circuit elements are located on side of the circuit board while the active circuit elements are located on the other side is described. The active circuit elements are embedded in a common heat sink so that a common temperature reference is provided for changes in ambient temperature. The single transistor and operational amplifier are connected together to form a feedback amplifier powered from the voltage regulator with transistor implementing primarily the desired signal gain while the operational amplifier implements signal isolation. Further RF isolation is provided by the voltage regulator which inhibits cross-talk from other like amplifiers powered from a common power supply. Input and output terminals consisting of coaxial connectors are located on the sides of a housing in which all the circuit components and heat sink are located.

  10. Seropersistence of TBE virus antibodies 10 years after first booster vaccination and response to a second booster vaccination with FSME-IMMUN 0.5mL in adults.

    PubMed

    Konior, R; Brzostek, J; Poellabauer, E M; Jiang, Q; Harper, L; Erber, W

    2017-06-16

    Tick-borne encephalitis (TBE) is a viral disease that can have a severe acute clinical course and considerable long-term morbidity. As there is no causal treatment currently available for TBE, vaccination is the only way to combat the disease in endemic areas. The studies presented here were conducted to obtain prospective long-term TBE serum antibody persistence data of subjects up to 10years after the first booster with FSME-IMMUN. This report presents the results of 2 follow-up studies in the same study population of 315 healthy adults. Blood was drawn to assess the seropersistence of TBE virus antibodies yearly, from 2-5 and 7-10years after the first booster vaccination with FSME-IMMUN administered during a previous study. The timing of the second booster vaccination was dependent on the level of serum TBE antibodies observed during yearly follow-up serology observations. The current follow up showed that adult recipients were 84.9% seropositive 10years after a 3 dose primary series and the first booster vaccination of FSME-IMMUN. Seropositivity rates were even higher (88.6%) in subjects below 50years of age. ClinicalTrials.gov Identifier: NCT00503529. ClinicalTrials.gov Identifier: NCT01582698. Copyright © 2017. Published by Elsevier Ltd.

  11. Is there a role for amplifiers in sexual selection?

    PubMed

    Gualla, Filippo; Cermelli, Paolo; Castellano, Sergio

    2008-05-21

    The amplifier hypothesis states that selection could favour the evolution of traits in signallers that improve the ability of receivers to extract honest information from other signals or cues. We provide a formal definition of amplifiers based on the receiver's mechanisms of signal perception and we present a game-theoretical model in which males advertise their quality and females use sequential-sampling tactics to choose among prospective mates. The main effect of an amplifier on the female mating strategy is to increase her mating threshold, making the female more selective as the effectiveness of the amplifier increases. The effects of the amplifier on male advertising strategy depends both on the context and on the types of the amplifier involved. We consider two different contexts for the evolution of amplifiers (when the effect of amplifiers is on signals and when it is on cues) and two types of amplifiers (the 'neutral amplifier', when it improves quality assessment without altering male attractiveness, and the 'attractive amplifier', when it improves both quality assessment and male attractiveness). The game-theoretical model provides two main results. First, neutral and attractive amplifiers represent, respectively, a conditional and an unconditional signalling strategy. In fact, at the equilibrium, neutral amplifiers are displayed only by males whose advertising level lays above the female acceptance threshold, whereas attractive amplifiers are displayed by all signalling males, independent of their quality. Second, amplifiers of signals increase the differences in advertising levels between amplifying and not-amplifying males, but they decrease the differences within each group, so that the system converges towards an 'all-or-nothing' signalling strategy. By applying concepts from information theory, we show that the increase in information transfer at the perception level due to the amplifier of signals is contrasted by a decrease in information

  12. On-Ramp: Improving students' understanding of lock-in amplifiers

    NASA Astrophysics Data System (ADS)

    DeVore, Seth; Singh, Chandralekha; Levy, Jeremy

    2013-03-01

    A lock-in amplifier is a powerful and versatile instrument which is used frequently in condensed matter physics research. However, many students struggle with the basics of a lock-in amplifier and they have difficulty in interpreting the data obtained with this device in diverse applications. To improve students' understanding, we are developing an ``On-Ramp'' tutorial based on physics education research which makes use of a computer simulation of a lock-in amplifier. During the development of the tutorial we interviewed several faculty members and graduate students. The tutorial is based on a field-tested approach in which students realize their difficulties after predicting the outcome of experiments that use a lock-in amplifier; students can check their predictions using simulations. The tutorial then guides students toward a coherent understanding of the basics of a lock-in amplifier. This poster will discuss the development and assessment process. This work is supported by NSF NEB (DMR-1124131) and NSF (PHY-1202909).

  13. Single mode terahertz quantum cascade amplifier

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ren, Y., E-mail: yr235@cam.ac.uk; Wallis, R.; Shah, Y. D.

    2014-10-06

    A terahertz (THz) optical amplifier based on a 2.9 THz quantum cascade laser (QCL) structure has been demonstrated. By depositing an antireflective coating on the QCL facet, the laser mirror losses are enhanced to fully suppress the lasing action, creating a THz quantum cascade (QC) amplifier. Terahertz radiation amplification has been obtained, by coupling a separate multi-mode THz QCL of the same active region design to the QC amplifier. A bare cavity gain is achieved and shows excellent agreement with the lasing spectrum from the original QCL without the antireflective coating. Furthermore, a maximum optical gain of ∼30 dB with single-modemore » radiation output is demonstrated.« less

  14. Effects of hepatitis B vaccine boosters on anti-HBs-negative children after primary immunization.

    PubMed

    Lu, Shunshun; Ren, Jingjing; Li, Qian; Jiang, Zhenggang; Chen, Yongdi; Xu, Kaijin; Ruan, Bing; Yang, Shigui; Xie, Tiansheng; Yang, Linna; Li, Jing; Yao, Jun

    2017-04-03

    This study was aimed at evaluating the changes of hepatitis B surface antibody (anti-HBs) titer after booster vaccinations in 5-15-year-old children with negative antibodies (<10 mIU/mL). 225 subjects (mean age, 9.28 ± 2.95 years) included in the study consisted of 123 males and 102 females, with a complete hepatitis B vaccination during infancy. The participants were divided into 3 groups according to their pre-booster anti-HBs level: Group I, <0.1 mIU/mL; Group II, 0.1 to <1.0 mIU/mL; Group III, 1.0 to <10.0 mIU/mL. All the participants were administered 3 doses of booster hepatitis B vaccination (0-1-6 month, 20 µg), and changes in the levels of antibodies were examined at 4 time-points (one month after the first and the third dose, one year and 5 years after the third dose). The seroprotective rate (defined as anti-HBs ≥10.0 mIU/mL) among 225 subjects at the 4 time-points were 93.8%, 100%, 83.6% and 73.4%, respectively (χ 2 = 90.29, p < 0.05). The seroprotective rate (≥10 mIU/mL) and anti-HBs geometric mean titer (GMT) in Group III were always higher than those in the other 2 groups (all p < 0.05). The immune effect of a 3 -dose booster revaccination is good, and the booster-induced immune response was correlated with the pre-booster titer level, and ≥1.0 mIU/mL ensuring a robust positive response, whereas titers below this value may indicate the need for a course of booster vaccination.

  15. Effect of Booster Seat Design on Children’s Choice of Seating Positions During Naturalistic Riding

    PubMed Central

    Andersson, Marianne; Bohman, Katarina; Osvalder, Anna-Lisa

    2010-01-01

    The purpose of this naturalistic study was to investigate the effect of booster seat design on the choice of children’s seating positions during naturalistic riding. Data was collected through observations of children during in-vehicle riding by means of a film camera. The children were positioned in high back boosters in the rear seat while a parent drove the car. The study included two different booster designs: one with large head and torso side supports, and one with small head side supports and no torso side supports. Six children between three and six years of age participated in the study. Each child was observed in both boosters. The duration of the seating positions that each child assumed was quantified. The design with large side head supports resulted more often in seating positions without head and shoulder contact with the booster’s back. There was shoulder-to-booster back contact during an average of 45% of riding time in the seat with the large head side supports compared to 75% in the seat with the small head supports. The children in the study were seated with the head in front of the front edge of the head side supports more than half the time, in both boosters. Laterally, the children were almost constantly positioned between the side supports of the booster in both seats. The observed seating positions probably reduce the desired protective effect by the side supports in side impact, and may increase the probability of head impact with the vehicle interior in frontal impact. PMID:21050601

  16. Interventions for promoting booster seat use in four to eight year olds traveling in motor vehicles.

    PubMed

    Ehiri, J E; Ejere, H O D; Magnussen, L; Emusu, D; King, W; Osberg, J S

    2006-01-25

    Public health and traffic safety agencies recommend use of booster seats in motor vehicles for children aged four to eight years, and various interventions have been implemented to increase their use by individuals who transport children in motor vehicles. There is little evidence regarding the effectiveness of these interventions, hence the need to examine what works and what does not. To assess the effectiveness of interventions intended to increase acquisition and use of booster seats in motor vehicles among four to eight year olds. We searched the Cochrane Injuries Group's Specialized Register, the Cochrane Central Register of Controlled Trials, MEDLINE (January 1966 to April 2005), EMBASE (1980 to April 2005), LILACS, Transport Research Databases (1988 to April 2005), Australian Transport Index (1976 to April 2005), additional databases and reference lists of relevant articles. We also contacted experts in the field. We included randomized and controlled before-and-after trials that investigated the effects of interventions to promote booster seat use. Two authors independently assessed trial quality and extracted data. Study authors were contacted for additional information. Five studies involving 3,070 individuals met the criteria for inclusion in the meta-analysis. All interventions for promoting use of booster seats among 4 to 8 year olds demonstrated a positive effect (relative risk (RR) 1.43; 95% confidence intervals (CI) 1.05 to 1.96). Incentives combined with education demonstrated a beneficial effect (RR 1.32, 95% CI 1.12 to 1.55; n = 1,898). Distribution of free booster seats combined with education also had a beneficial effect (RR 2.34; 95% CI 1.50 to 3.63; n = 380) as did education-only interventions (RR 1.32; 95% CI 1.16 to 1.49; n = 563). One study which evaluated enforcement of booster seat law met the criteria for inclusion in the meta-analysis, but demonstrated no marked beneficial effect. Available evidence suggests that interventions to

  17. Broadband laser amplifier based on gas-phase dimer molecules pumped by the Sun.

    PubMed

    Pe'er, I; Vishnevitsky, I; Naftali, N; Yogev, A

    2001-09-01

    We report the design and experimental realization of a solar-pumped dimer gas-laser amplifier. The amplifying medium is Te(2) gas, which is capable of amplifying laser signals over a broad spectral range. A gain of 42% was measured at a wavelength of 632.8 nm. We also present studies of the material characteristics and a brief review of the study of other candidate materials for solar pumping.

  18. Design of a lock-amplifier circuit

    NASA Astrophysics Data System (ADS)

    Liu, H.; Huang, W. J.; Song, X.; Zhang, W. Y.; Sa, L. B.

    2017-01-01

    The lock-in amplifier is recovered by phase sensitive detection technique for the weak signal submerged in the noise background. This design is based on the TI ultra low power LM358, INA129, OPA227, OP07 and other chips as the core design and production of the lock-in amplifier. Signal generator by 10m ohms /1K ohm resistance points pressure network 10 mu V 1mV adjustable sine wave signal s (T). The concomitant interference signal together through the AC amplifier and band-pass filter signal x (T), on the other hand reference signal R (T) driven by square wave phase shift etc. steps to get the signal R (T), two signals and by phase sensitive detector are a DC full wave, again through its low pass filter and a DC amplifier to be measured signal more accurate detection, the final circuit through the AD conversion and the use of single-chip will display the output.

  19. Integration & Validation of LCU with Different Sub-systems for Diacrode based amplifier

    NASA Astrophysics Data System (ADS)

    Rajnish, Kumar; Verma, Sriprakash; Soni, Dipal; Patel, Hriday; Suthar, Gajendra; Dalicha, Hrushikesh; Dhola, Hitesh; Patel, Amit; Upadhayay, Dishang; Jha, Akhil; Patel, Manoj; Trivedi, Rajesh; Machchhar, Harsha; Singh, Raghuraj; Mukherjee, Aparajita

    2017-04-01

    ITER-India is responsible to deliver nine (8+1 spare) ICH & CD Power Sources to ITER. Each power source is capable to deliver 2.5 MW at 35 to 65 MHz frequency range with a load condition up to VSWR 2:1. For remote operation of different subsystems, Local Control Unit (LCU) is developed. LCU is developed using PXI hardware and Schneider PLC with Lab VIEW-RT developmental environment. All the protection function of the amplifier is running on PXI 7841 R module that ensures hard wired protection logic. There are three level of protection function- first by power supply itself that detects overcurrent/overvoltage and trips itself and generate trip signal for further action. There are some direct hardwired signal interfaces between power supplies to protect the amplifier. Second level of protection is generated through integrated controller of amplifier i.e. Command Control Embedded (CCE) against arc and Anode over current. Third level of Protection is through LCU where different fault signals are received and processed to generate off command for different sub-systems. Before connecting different subsystem with High power RF amplifiers (Driver & Final stage), each subsystem is individually tested through LCU. All protection functions are tested before hooking up the subsystems with main amplifier and initiating RF operation.

  20. Investigation of Post-Flight Solid Rocket Booster Thermal Protection System

    NASA Technical Reports Server (NTRS)

    Nelson, Linda A.

    2006-01-01

    After every Shuttle mission, the Solid Rocket Boosters (SRBs) are recovered and observed for missing material. Most of the SRB is covered with a cork-based thermal protection material (MCC-l). After the most recent shuttle mission, STS-114, the forward section of the booster appeared to have been impacted during flight. The darkened fracture surfaces indicated that this might have occurred early in flight. The scope of the analysis included microscopic observations to assess the degree of heat effects and locate evidence of the impact source as well as chemical analysis of the fracture surfaces and recovered foreign material using Fourier Transform Infrared Spectroscopy and Scanning Electron Microscopy/Energy Dispersive Spectroscopy. The amount of heat effects and presence of soot products on the fracture surface indicated that the material was impacted prior to SRB re-entry into the atmosphere. Fragments of graphite fibers found on these fracture surfaces were traced to slag inside the Solid Rocket Motor (SRM) that forms during flight as the propellant is spent and is ejected throughout the descent of the SRB after separation. The direction of the impact mark matches with the likely trajectory of SRBs tumbling prior to re-entry.

  1. Operational Amplifiers.

    ERIC Educational Resources Information Center

    Foxcroft, G. E.

    1986-01-01

    Addresses the introduction of low cost equipment into high school and college physical science classes. Examines the properties of an "ideal" operational amplifier and discusses how it might be used under saturated and non-saturated conditions. Notes the action of a "real" operational amplifier. (TW)

  2. A low-power CMOS operational amplifier IC for a heterogeneous paper-based potentiostat

    NASA Astrophysics Data System (ADS)

    Bezuidenhout, P.; Land, K.; Joubert, T.-H.

    2016-02-01

    Electrochemical biosensing is used to detect specific analytes in fluids, such as bacterial and chemical contaminants. A common implementation of an electrochemical readout is a potentiostat, which usually includes potentiometric, amperometric, and impedimetric detection. Recently several researchers have developed small, low-cost, single-chip silicon-based potentiostats. With the advances in heterogeneous integration technology, low-power potentiostats can be implemented on paper and similar low cost substrates. This paper deals with the design of a low-power paper-based amperometric front-end for a low-cost and rapid detection environment. In amperometric detection a voltage signal is provided to a sensor system, while a small current value generated by an electrochemical redox reaction in the system is measured. In order to measure low current values, the noise of the circuit must be minimized, which is accomplished with a pre-amplification front-end stage, typically designed around an operational amplifier core. An appropriate circuit design for a low-power and low-cost amperometric front-end is identified, taking the heterogeneous integration of various components into account. The operational amplifier core is on a bare custom CMOS chip, which will be integrated onto the paper substrate alongside commercial off-the-shelf electronic components. A general-purpose low-power two-stage CMOS amplifier circuit is designed and simulated for the ams 350 nm 5 V process. After the layout design and verification, the IC was submitted for a multi-project wafer manufacturing run. The simulated results are a bandwidth of 2.4 MHz, a common-mode rejection ratio of 70.04 dB, and power dissipation of 0.154 mW, which are comparable with the analytical values.

  3. Figures of merit for microwave photonic phase shifters based on semiconductor optical amplifiers.

    PubMed

    Sancho, Juan; Lloret, Juan; Gasulla, Ivana; Sales, Salvador; Capmany, José

    2012-05-07

    We theoretically and experimentally compare the performance of two fully tunable phase shifter structures based on semiconductor optical amplifiers (SOA) by means of several figures of merit common to microwave photonic systems. A single SOA stage followed by a tailored notch filter is compared with a cascaded implementation comprising three SOA-based phase shifter stages. Attention is focused on the assessment of the RF net gain, noise figure and nonlinear distortion. Recommendations on the performance optimization of this sort of approaches are detailed.

  4. Cabling design of booster and storage ring construction progress of TPS

    NASA Astrophysics Data System (ADS)

    Wong, Y.-S.; Liu, K.-B.; Liu, C.-Y.; Wang, b.-S.

    2017-06-01

    The 2012 Taiwan Photon Source (TPS) cable construction project started after 10 months to complete the cable laying and installation of power supply. The circumference of the booster ring (BR) is 496.8 m, whereas that of the storage ring (SR) is 518.4 m. Beam current is set to 500 mA at 3.3 GeV. The paper on grounding systems discusses the design of the ground wire (< 0.2 Ω) with low impedance, power supply of the accelerator and cabling tray. The flow and size of the ground current are carefully evaluated to avoid grounded current from flowing everywhere, which causes interference problems. In the design of the TPS, special shielding will be established to isolate the effects of electromagnetic interference on the magnet and ground current. Booster ring dipoles are connected by a series of 54-magnet bending dipole; the cable size of its stranded wire measures 250 mm2, with a total length of 5000 m. Booster ring and storage ring quadrupoles have 150 magnets; the cable size of their stranded wire is 250 mm2, with a total length of 17000 m. Storage ring dipole consists of 48 magnets; the cable size of its stranded wire is 325 mm2, with a total length of 6000 m. This study discusses the power supply cabling design of the storage ring and booster ring construction progress of TPS. The sections of this paper are divided into discussions of the construction of the control and instrument area, cabling layout of booster ring and storage ring, as well as the installation and commission machine. This study also discusses the use of a high-impedance meter to determine the effect of cabling insulation and TPS power supply machine on energy transfer to ensure the use of safe and correct magnet.

  5. Seroprevalence of tetanus toxoid antibody and booster vaccination efficacy in Japanese travelers.

    PubMed

    Mizuno, Yasutaka; Yamamoto, Akihiko; Komiya, Takako; Takeshita, Nozomi; Takahashi, Motohide

    2014-01-01

    Tetanus can be prevented by vaccination, which is especially important for overseas travelers. However, despite booster vaccination every 10 years being recommended, most Japanese adults do not receive it in the absence of physical injury or overseas travel. We aimed to investigate the level of protective immunity against tetanus among Japanese travelers, which may provide valuable information for formulating booster vaccination recommendations. 113 Japanese travelers given tetanus toxoid were recruited. The collected samples included paired samples prior to and 3-5 weeks after receiving the booster vaccination. Travelers who did not return and those lacking sample collection at the second visit were excluded. Finally, 96 paired blood samples were collected. History of immunization against tetanus, including DPT and DT vaccines, was determined from interviews or immunization records. The pre-vaccination geometric mean titer for the 96 participants was 1.07 IU/mL; 76% had a protective antitoxin level (>0.1 IU/mL), and 50% had a long-term protective antitoxin level (>1.0 IU/mL). Most participants <40 years old had protective immunity without receiving booster vaccination, whereas only 30.8% of those >50 years of age had protective immunity. Among the 23 participants without protective antitoxin levels (<0.1 IU/mL), booster vaccination was efficient in 100% of those <40 years but in only 28.6% of those >50 years of age. Although the tetanus antitoxin level decreases with age, booster vaccination helped to achieve an adequate protective antitoxin levels in Japanese travelers <40 years of age. Furthermore, the individuals who have never been vaccinated against tetanus especially in those >50 years old need to obtain protective immunity against tetanus according to a basic immunization schedule to prevent tetanus in travelers and residents of Japan. Copyright © 2013 Japanese Society of Chemotherapy and the Japanese Association for Infectious Diseases. Published by

  6. Ultrasensitive aptamer-based protein detection via a dual amplified biocatalytic strategy

    PubMed Central

    Xiang, Yun; Zhang, Yuyong; Qian, Xiaoqing; Chai, Yaqin; Wang, Joseph; Yuan, Ruo

    2010-01-01

    We present an ultrasensitive aptasensor for electronic monitoring of proteins through a dual amplified strategy in this paper. The target protein thrombin is sandwiched between an electrode surface confined aptamer and an aptamer-enzyme-carbon nanotube bioconjugate. The analytical signal amplification is achieved by coupling the signal amplification nature of multiple enzymes with the biocatalytic signal enhancement of redox-recycling. Our novel dramatic signal amplification strategy, with a detection limit of 8.3 fM, shows about 4 orders of magnitude improvement in sensitivity for thrombin detection compared to other universal single enzyme-based assay. This makes our approach an attractive alternative to other common PCR-based signal amplification in ultralow level of protein detection. PMID:20452761

  7. Clinical and economic assessment of different general population strategies of pertussis vaccine booster regarding number of doses and age of application for reducing whooping cough disease burden: a systematic review.

    PubMed

    Rodríguez-Cobo, Iria; Chen, Yen-Fu; Olowokure, Babatunde; Litchfield, Ian

    2008-12-09

    Pertussis continues to be an important cause of morbidity and mortality in children too young to be fully protected despite high vaccination coverage. This has been attributed to waning immunity in older people, leading to the development of strategies to increase levels of immunity. A systematic review was conducted to assess the clinical and cost effectiveness of four population-based strategies for pertussis booster vaccination: single booster at 12-24 months old, single pre-school booster, single adolescent booster and multiple boosters in adulthood every 10 years. Electronic databases and Internet resources were searched to June 2006. Nine observational studies, four mathematical models and eight economic evaluations were included, evaluating four different strategies. Strong evidence to recommend any of these strategies was not found.

  8. Development of Cogging at the Fermilab Booster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seiya, K.; Chaurize, S.; Drennan, C.

    2015-01-30

    The development of magnetic cogging is part of the Fermilab Booster upgrade within the Proton Improvement Plan (PIP). The Booster is going to send 2.25E17 protons/hour which is almost double the present flux, 1.4E17 protons/hour to the Main Injector (MI) and Recycler (RR). The extraction kicker gap has to synchronize to the MI and RR injection bucket in order to avoid a beam loss at the rising edge of the extraction and injection kickers. Magnetic cogging is able to control the revolution frequency and the position of the gap using the magnetic field from dipole correctors while radial position feedbackmore » keeps the beam at the central orbit. The new cogging is expected to reduce beam loss due to the orbit changes and reduce beam energy loss when the gap is created. The progress of the magnetic cogging system development is going to be discussed in this paper.« less

  9. X-43A hypersonic research aircraft mated to its modified Pegasus booster rocket.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The first of three X-43A hypersonic research aircraft was mated to its modified Pegasus booster rocket in late January at NASA's Dryden Flight Research Center, Edwards, Calif. FIRST X-43A MATED TO BOOSTER -- The first of three X-43A hypersonic research aircraft was mated to its modified Pegasus booster rocket in late January at NASA's Dryden Flight Research Center, Edwards, Calif. Mating of the X-43A and its specially-designed adapter to the first stage of the booster rocket marks a major milestone in the Hyper-X hypersonic research program. The 12-foot, unpiloted research vehicle was developed and built by MicroCraft Inc., Tullahoma, Tenn., for NASA. The booster, built by Orbital Sciences Corp., Dulles, Va., will accelerate the X-43A after the X-43A booster 'stack' is air-launched from NASA's venerable NB-52 mothership. The X-43A will separate from the rocket at a predetermined altitude and speed and fly a pre-programmed trajectory, conducting aerodynamic and propulsion experiments until it impacts into the Pacific Ocean. Three research flights are planned, two at Mach 7 and one at Mach 10 (seven and 10 times the speed of sound respectively) with the first tentatively scheduled for early summer of 2001. The X-43A is powered by a revolutionary supersonic-combustion ramjet ('scramjet') engine, and will use the underbody of the aircraft to form critical elements of the engine. The forebody shape helps compress the intake airflow, while the aft section acts as a nozzle to direct thrust. The X-43A flights will be the first actual flight tests of an aircraft powered by an air-breathing scramjet engine.

  10. [Immune response to one booster dose of inactivated hepatitis A vaccine in college students].

    PubMed

    Liao, Z; Feng, X W; Liu, X E; Zhou, Y S; Wen, H R; Peng, S H; Zhang, Y X; Xu, B; Zhuang, H; Chen, H Y

    2017-05-10

    Objective: To evaluate the safety and immunogenicity of one booster dose of inactivated hepatitis A vaccine in young adults. Methods: The subjects were selected from participants in the clinical trial of immunogenicity of inactivated and attenuated live hepatitis A vaccine in young adults. Eligible subjects were those who had received one dose of inactivated or attenuated hepatitis A vaccine, could be contacted and were sero-negative before primary vaccination. All qualified subjects were immunized with one booster dose of inactivated hepatitis A vaccine. The blood samples were collected before booster dose vaccination and 28 days after the immunization. Anti-HAV antibody titer ≥20 mIU/ml was considered to be sero-protected against hepatitis A virus. Results: The GMCs in the inactivated HAV vaccine group and attenuated live vaccine group before booster dose vaccination were 70.80 mIU/ml and 50.12 mIU/ml, respectively, and the sero-protection rates were 94.7 % and 65.0 % , respectively. After the vaccination of the booster dose, the sero-protection rates in both groups were 100.0 % , and the GMCs were 2 816.09 mIU/ml and 2 654.55 mIU/ml, respectively. Conclusion: The GMCs and sero-protection rates of anti-HAV antibody in young adults declined after three years of the primary vaccination. However, the higher GMC and sero-protection rate were observed in the inactivated vaccine group than in the attenuated live vaccine group. Significant increases of GMC levels were observed in both groups after one booster dose vaccination.

  11. Long-term immunogenicity of an initial booster dose of an inactivated, Vero cell culture-derived Japanese encephalitis vaccine (JE-VC) and the safety and immunogenicity of a second JE-VC booster dose in children previously vaccinated with an inactivated, mouse brain-derived Japanese encephalitis vaccine.

    PubMed

    Yun, Ki Wook; Lee, Hoan Jong; Park, Ji Young; Cho, Hye-Kyung; Kim, Yae-Jean; Kim, Kyung-Hyo; Kim, Nam Hee; Hong, Young Jin; Kim, Dong Ho; Kim, Hwang Min; Cha, Sung-Ho

    2018-03-07

    This study was performed with the aim of determining the long-term immunogenicity of an inactivated, Vero cell culture-derived Japanese encephalitis (JE) vaccine (JE-VC) and an inactivated, mouse brain-derived JE vaccine (JE-MB) after the 1st booster dose at 2 years of age, as well as the safety and immunogenicity of the 2nd booster dose of JE-VC at 6 years of age, in children primed and given a 1st booster dose of either JE-VC or JE-MB. In this multicenter, open-label clinical trial, the study population consisted of healthy Korean children (aged 6 years) who participated in the previous JE vaccine trial. All subjects were subcutaneously vaccinated once for the booster immunization with Boryung Cell Culture Japanese Encephalitis Vaccine® (JE-VC). Approximately 4 years after the 1st booster dose of JE-VC, the seroprotection rate (SPR) and geometric mean titer (GMT) of the neutralizing antibody were 100% and 1113.8, respectively. In children primed and given a 1st booster dose of JE-MB, the SPR and GMT were 88.5% and 56.3, respectively. After the 2nd booster dose of JE-VC, all participants primed and given a 1st booster dose of either JE-MB or JE-VC were seroprotective against JE virus. The GMT of the neutralizing antibody was higher in children primed and given a 1st booster dose of JE-VC (8144.1) than in those primed and given a 1st booster dose of JE-MB (942.5) after the vaccination (p < 0.001). In addition, the 2nd booster dose of JE-VC showed a good safety profile with no serious vaccine-related adverse events. The 1st booster dose of JE-VC and JE-MB showed long-term immunogenicity of at least 4 years, and the 2nd booster dose of JE-VC showed a good safety and immunogenicity profile in children primed and given a 1st booster dose of either JE-VC or JE-MB. ClinicalTtrials.gov Identifier: NCT02532569. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51.

    PubMed

    Olsen, S C; McGill, J L; Sacco, R E; Hennager, S G

    2015-04-01

    Thirty-one bison heifers were randomly assigned to receive saline or a single vaccination with 10(10) CFU of Brucella abortus strain RB51. Some vaccinated bison were randomly selected for booster vaccination with RB51 at 11 months after the initial vaccination. Mean antibody responses to RB51 were greater (P < 0.05) in vaccinated bison after initial and booster vaccination than in nonvaccinated bison. The proliferative responses by peripheral blood mononuclear cells (PBMC) from the vaccinated bison were greater (P < 0.05) than those in the nonvaccinated bison at 16 and 24 weeks after the initial vaccination but not after the booster vaccination. The relative gene expression of gamma interferon (IFN-γ) was increased (P < 0.05) in the RB51-vaccinated bison at 8, 16, and 24 weeks after the initial vaccination and at 8 weeks after the booster vaccination. The vaccinated bison had greater (P < 0.05) in vitro production of IFN-γ at all sampling times, greater interleukin-1β (IL-1β) production in various samplings after the initial and booster vaccinations, and greater IL-6 production at one sampling time after the booster vaccination. Between 170 and 180 days of gestation, the bison were intraconjunctivally challenged with approximately 1 × 10(7) CFU of B. abortus strain 2308. The incidences of abortion and infection were greater (P < 0.05) in the nonvaccinated bison after experimental challenge than in the bison receiving either vaccination treatment. Booster-vaccinated, but not single-vaccinated bison, had a reduced (P < 0.05) incidence of infection in fetal tissues and maternal tissues compared to that in the controls. Compared to the nonvaccinated bison, both vaccination treatments lowered the colonization (measured as the CFU/g of tissue) of Brucella organisms in all tissues, except in retropharyngeal and supramammary lymph nodes. Our study suggests that RB51 booster vaccination is an effective vaccination strategy for enhancing herd immunity against

  13. Immune Responses of Bison and Efficacy after Booster Vaccination with Brucella abortus Strain RB51

    PubMed Central

    McGill, J. L.; Sacco, R. E.; Hennager, S. G.

    2015-01-01

    Thirty-one bison heifers were randomly assigned to receive saline or a single vaccination with 1010 CFU of Brucella abortus strain RB51. Some vaccinated bison were randomly selected for booster vaccination with RB51 at 11 months after the initial vaccination. Mean antibody responses to RB51 were greater (P < 0.05) in vaccinated bison after initial and booster vaccination than in nonvaccinated bison. The proliferative responses by peripheral blood mononuclear cells (PBMC) from the vaccinated bison were greater (P < 0.05) than those in the nonvaccinated bison at 16 and 24 weeks after the initial vaccination but not after the booster vaccination. The relative gene expression of gamma interferon (IFN-γ) was increased (P < 0.05) in the RB51-vaccinated bison at 8, 16, and 24 weeks after the initial vaccination and at 8 weeks after the booster vaccination. The vaccinated bison had greater (P < 0.05) in vitro production of IFN-γ at all sampling times, greater interleukin-1β (IL-1β) production in various samplings after the initial and booster vaccinations, and greater IL-6 production at one sampling time after the booster vaccination. Between 170 and 180 days of gestation, the bison were intraconjunctivally challenged with approximately 1 × 107 CFU of B. abortus strain 2308. The incidences of abortion and infection were greater (P < 0.05) in the nonvaccinated bison after experimental challenge than in the bison receiving either vaccination treatment. Booster-vaccinated, but not single-vaccinated bison, had a reduced (P < 0.05) incidence of infection in fetal tissues and maternal tissues compared to that in the controls. Compared to the nonvaccinated bison, both vaccination treatments lowered the colonization (measured as the CFU/g of tissue) of Brucella organisms in all tissues, except in retropharyngeal and supramammary lymph nodes. Our study suggests that RB51 booster vaccination is an effective vaccination strategy for enhancing herd immunity against brucellosis in

  14. Delta II ICESat-2 Booster Arrival

    NASA Image and Video Library

    2018-03-09

    A United Launch Alliance Delta II booster arrives at NASA's Building 836, the Spacecraft Labs Telemetry Station at Vandenberg Air Force Base in California. It will be offloaded and begin preliminary checkouts and preflight processing for launch of the agency's Ice, Cloud and land Elevation Satellite-2, or ICESat-2. Liftoff from Space Launch Complex-2 at Vandenberg is scheduled for Sept. 12, 2018, and will be the last for the venerable Delta II rocket. Once in orbit, the satellite is designed to measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much, Earth's frozen and icy areas are changing. These area make up Earth's the cryosphere.

  15. TDRS-M Atlas V Booster and Centaur Stages Offload, Booster Trans

    NASA Image and Video Library

    2017-06-27

    At Port Canaveral in Florida, a United Launch Alliance Atlas V rocket booster is transported from the company's Mariner ship to the Atlas Spaceflight Operations Center at Cape Canaveral Air Force Station. The rocket is scheduled to launch the Tracking and Data Relay Satellite, TDRS-M. It will be the latest spacecraft destined for the agency's constellation of communications satellites that allows nearly continuous contact with orbiting spacecraft ranging from the International Space Station and Hubble Space Telescope to the array of scientific observatories. Liftoff atop the ULA Atlas V rocket is scheduled to take place from Cape Canaveral's Space Launch Complex 41 on Aug. 3, 2017 at 9:02 a.m. EDT.

  16. Liquid Flyback Booster Pre-Phase A Study Assessment. Volume 1

    NASA Technical Reports Server (NTRS)

    Peterson, W.; Ankney, W.; Bell, J.; Berning, M.; Bryant, L.; Bufkin, A.; Cain, L.; Caram, J.; Cockrell, B.; Curry, D.; hide

    1994-01-01

    Mw concept of a flyback booster has been around since early in the Shuttle program. The original two-stage Shuttle concepts used a manned flyback booster. These boosters were eliminated from the program for funding and size reasons. The current Shuttle uses two Redesigned Solid Rocket Motors (RSRMs), which are recovered and refurbished after each flight; this is one of the major cost factors of the program. Replacement options have been studied over the past ten years. The conclusion reached by the most recent study is that the liquid flyback booster (LFBB) is the only competitive option from a life-cycle cost perspective. The purpose of this study was to assess the feasibility and practicality of LFBBs. The study provides an expansion of the recommendations made during the during the aforementioned study. The primary benefits are the potential for enhanced reusability and a reuction of recurring costs. The potential savings in vehicle turnaround could offset the up-front costs. Development of LFBBs requires a commitment to the Shuttle program for 20 to 30 years. LFBBs also offer enhanced safety and abort capabilities. Currently, any failure of an RSRM can be considered catastrophic since them we no intact abort capabilities during the burn of the RSRMS. The performance goal of the LFBBs was to lift a fully loaded Orbiter under optimal conditions, so as not to be the limiting factor of the performance capability of the Shuttle. In addition, a final benefit is the availability of growth paths for applications other than the Shuttle.

  17. GOES-S Atlas V Booster and Centaur Stages Arrival, Offload, and

    NASA Image and Video Library

    2018-01-22

    The United Launch Alliance Atlas V booster for NOAA's Geostationary Operational Environmental Satellite-S (GOES-S) was offloaded from the Mariner transport ship at the Army Wharf at Cape Canaveral Air Force Station in Florida. The booster will be transported to the Atlas Spaceflight Operations Center near Space Launch Complex 41 at CCAFS. GOES-S is the second in a series of four advanced geostationary weather satellites. The satellite is slated to launch aboard the Atlas V rocket March 1.

  18. GOES-S Atlas V Booster and Centaur Stages Arrival, Offload, and

    NASA Image and Video Library

    2018-01-22

    The United Launch Alliance Atlas V booster for NOAA's Geostationary Operational Environmental Satellite-S (GOES-S) is offloaded from the Mariner transport ship at the Army Wharf at Cape Canaveral Air Force Station in Florida. The booster will be transported to the Atlas Spaceflight Operations Center near Space Launch Complex 41 at CCAFS. GOES-S is the second in a series of four advanced geostationary weather satellites. The satellite is slated to launch aboard the Atlas V rocket March 1.

  19. Quantitative Index and Abnormal Alarm Strategy Using Sensor-Dependent Vibration Data for Blade Crack Identification in Centrifugal Booster Fans

    PubMed Central

    Chen, Jinglong; Sun, Hailiang; Wang, Shuai; He, Zhengjia

    2016-01-01

    Centrifugal booster fans are important equipment used to recover blast furnace gas (BFG) for generating electricity, but blade crack faults (BCFs) in centrifugal booster fans can lead to unscheduled breakdowns and potentially serious accidents, so in this work quantitative fault identification and an abnormal alarm strategy based on acquired historical sensor-dependent vibration data is proposed for implementing condition-based maintenance for this type of equipment. Firstly, three group dependent sensors are installed to acquire running condition data. Then a discrete spectrum interpolation method and short time Fourier transform (STFT) are applied to preliminarily identify the running data in the sensor-dependent vibration data. As a result a quantitative identification and abnormal alarm strategy based on compound indexes including the largest Lyapunov exponent and relative energy ratio at the second harmonic frequency component is proposed. Then for validation the proposed blade crack quantitative identification and abnormality alarm strategy is applied to analyze acquired experimental data for centrifugal booster fans and it has successfully identified incipient blade crack faults. In addition, the related mathematical modelling work is also introduced to investigate the effects of mistuning and cracks on the vibration features of centrifugal impellers and to explore effective techniques for crack detection. PMID:27171083

  20. Blood Pressure Directed Booster Trainings Improve Intensive Care Unit Provider Retention of Excellent Cardiopulmonary Resuscitation Skills.

    PubMed

    Wolfe, Heather; Maltese, Matthew R; Niles, Dana E; Fischman, Elizabeth; Legkobitova, Veronika; Leffelman, Jessica; Berg, Robert A; Nadkarni, Vinay M; Sutton, Robert M

    2015-11-01

    Brief, intermittent cardiopulmonary resuscitation (CPR) training sessions, "Booster Trainings," improve CPR skill acquisition and short-term retention. The objective of this study was to incorporate arterial blood pressure (ABP) tracings into Booster Trainings to improve CPR skill retention. We hypothesized that ABP-directed CPR "Booster Trainings" would improve intensive care unit (ICU) provider 3-month retention of excellent CPR skills without need for interval retraining. A CPR manikin creating a realistic relationship between chest compression depth and ABP was used for training/testing. Thirty-six ICU providers were randomized to brief, bedside ABP-directed CPR manikin skill retrainings: (1) Booster Plus (ABP visible during training and testing) versus (2) Booster Alone (ABP visible only during training, not testing) versus (3) control (testing, no intervention). Subjects completed skill tests pretraining (baseline), immediately after training (acquisition), and then retention was assessed at 12 hours, 3 and 6 months. The primary outcome was retention of excellent CPR skills at 3 months. Excellent CPR was defined as systolic blood pressure of 100 mm Hg or higher and compression rate 100 to 120 per minute. Overall, 14 of 24 (58%) participants acquired excellent CPR skills after their initial training (Booster Plus 75% vs 50% Booster Alone, P = 0.21). Adjusted for age, ABP-trained providers were 5.2× more likely to perform excellent CPR after the initial training (95% confidence interval [95% CI], 1.3-21.2; P = 0.02), and to retain these skills at 12 hours (adjusted odds ratio, 4.4; 95% CI, 1.3-14.9; P = 0.018) and 3 months (adjusted odds ratio, 4.1; 95% CI, 1.2-13.9; P = 0.023) when compared to baseline performance. The ABP-directed CPR booster trainings improved ICU provider 3-month retention of excellent CPR skills without the need for interval retraining.

  1. Inviscid and Viscous CFD Analysis of Booster Separation for the Space Launch System Vehicle

    NASA Technical Reports Server (NTRS)

    Dalle, Derek J.; Rogers, Stuart E.; Chan, William M.; Lee, Henry C.

    2016-01-01

    This paper presents details of Computational Fluid Dynamic (CFD) simulations of the Space Launch System during solid-rocket booster separation using the Cart3D inviscid and Overflow viscous CFD codes. The discussion addresses the use of multiple data sources of computational aerodynamics, experimental aerodynamics, and trajectory simulations for this critical phase of flight. Comparisons are shown between Cart3D simulations and a wind tunnel test performed at NASA Langley Research Center's Unitary Plan Wind Tunnel, and further comparisons are shown between Cart3D and viscous Overflow solutions for the flight vehicle. The Space Launch System (SLS) is a new exploration-class launch vehicle currently in development that includes two Solid Rocket Boosters (SRBs) modified from Space Shuttle hardware. These SRBs must separate from the SLS core during a phase of flight where aerodynamic loads are nontrivial. The main challenges for creating a separation aerodynamic database are the large number of independent variables (including orientation of the core, relative position and orientation of the boosters, and rocket thrust levels) and the complex flow caused by exhaust plumes of the booster separation motors (BSMs), which are small rockets designed to push the boosters away from the core by firing partially in the direction opposite to the motion of the vehicle.

  2. Microwave phase shifter with controllable power response based on slow- and fast-light effects in semiconductor optical amplifiers.

    PubMed

    Xue, Weiqi; Sales, Salvador; Capmany, José; Mørk, Jesper

    2009-04-01

    We suggest and experimentally demonstrate a method for increasing the tunable rf phase shift of semiconductor waveguides while at the same time enabling control of the rf power. This method is based on the use of slow- and fast-light effects in a cascade of semiconductor optical amplifiers combined with the use of spectral filtering to enhance the role of refractive index dynamics. A continuously tunable phase shift of approximately 240 degrees at a microwave frequency of 19 GHz is demonstrated in a cascade of two semiconductor optical amplifiers, while maintaining an rf power change of less than 1.6 dB. The technique is scalable to more amplifiers and should allow realization of an rf phase shift of 360 degrees.

  3. EM-1 Booster Prep, Right Aft Skirt Work-In-Progress

    NASA Image and Video Library

    2016-10-30

    The right hand aft skirt for NASA's Space Launch System (SLS) rocket has been refurbished and painted and is ready for the assembly process in the Booster Fabrication Facility at the agency's Kennedy Space Center in Florida. The aft skirt was refurbished and painted in support facilities at the Hangar AF facility at Cape Canaveral Air Force Station in Florida. The space shuttle-era aft skirt will be used on the right hand booster of the SLS for Exploration Mission 1 (EM-1). NASA is preparing for EM-1, deep space missions, and the Journey to Mars.

  4. Phase noise in RF and microwave amplifiers.

    PubMed

    Boudot, Rodolphe; Rubiola, Enrico

    2012-12-01

    Understanding amplifier phase noise is a critical issue in many fields of engineering and physics, such as oscillators, frequency synthesis, telecommunication, radar, and spectroscopy; in the emerging domain of microwave photonics; and in exotic fields, such as radio astronomy, particle accelerators, etc. Focusing on the two main types of base noise in amplifiers, white and flicker, the power spectral density of the random phase φ(t) is Sφ(f) = b(0) + b(-1)/f. White phase noise results from adding white noise to the RF spectrum in the carrier region. For a given RF noise level, b(0) is proportional to the reciprocal of the carrier power P(0). By contrast, flicker results from a near-dc 1/f noise-present in all electronic devices-which modulates the carrier through some parametric effect in the semiconductor. Thus, b(-1) is a parameter of the amplifier, constant in a wide range of P(0). The consequences are the following: Connecting m equal amplifiers in parallel, b(-1) is 1/m times that of one device. Cascading m equal amplifiers, b(-1) is m times that of one amplifier. Recirculating the signal in an amplifier so that the gain increases by a power of m (a factor of m in decibels) as a result of positive feedback (regeneration), we find that b(-1) is m(2) times that of the amplifier alone. The feedforward amplifier exhibits extremely low b(-1) because the carrier is ideally nulled at the input of its internal error amplifier. Starting with an extensive review of the literature, this article introduces a system-oriented model which describes the phase flickering. Several amplifier architectures (cascaded, parallel, etc.) are analyzed systematically, deriving the phase noise from the general model. There follow numerous measurements of amplifiers using different technologies, including some old samples, and in a wide frequency range (HF to microwaves), which validate the theory. In turn, theory and results provide design guidelines and give suggestions for CAD and

  5. Noise reduction in plasmonic amplifiers

    NASA Astrophysics Data System (ADS)

    Vyshnevyy, Andrey A.; Fedyanin, Dmitry Yu.

    2018-06-01

    Surface plasmon polaritons amplification give the possibility to overcome strong absorption in metals and design truly nanoscale devices for on-chip photonic circuits. However, the process of stimulated emission in the gain medium is inevitably accompanied by spontaneous emission, which greatly increases the noise power. Herein we present an efficient strategy for noise reduction in plasmonic amplifiers,which is based on gain redistribution along the amplifier. We show that even a very small gain redistribution (∼3%) makes it possible to increase the signal-to-noise ratio by ∼100% and improve the bit error ratio by orders of magnitude.

  6. 47 CFR 74.780 - Broadcast regulations applicable to translators, low power, and booster stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Broadcast regulations applicable to translators... PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.780 Broadcast regulations applicable to translators, low power, and booster stations. The following rules are applicable to...

  7. Broadband linearisation of high-efficiency power amplifiers

    NASA Technical Reports Server (NTRS)

    Kenington, Peter B.; Parsons, Kieran J.; Bennett, David W.

    1993-01-01

    A feedforward-based amplifier linearization technique is presented which is capable of yielding significant improvements in both linearity and power efficiency over conventional amplifier classes (e.g. class-A or class-AB). Theoretical and practical results are presented showing that class-C stages may be used for both the main and error amplifiers yielding practical efficiencies well in excess of 30 percent, with theoretical efficiencies of much greater than 40 percent being possible. The levels of linearity which may be achieved are required for most satellite systems, however if greater linearity is required, the technique may be used in addition to conventional pre-distortion techniques.

  8. Performance evaluation of Space Shuttle SRB parachutes from air drop and scaled model wind tunnel tests. [Solid Rocket Booster recovery system

    NASA Technical Reports Server (NTRS)

    Moog, R. D.; Bacchus, D. L.; Utreja, L. R.

    1979-01-01

    The aerodynamic performance characteristics have been determined for the Space Shuttle Solid Rocket Booster drogue, main, and pilot parachutes. The performance evaluation on the 20-degree conical ribbon parachutes is based primarily on air drop tests of full scale prototype parachutes. In addition, parametric wind tunnel tests were performed and used in parachute configuration development and preliminary performance assessments. The wind tunnel test data are compared to the drop test results and both sets of data are used to determine the predicted performance of the Solid Rocket Booster flight parachutes. Data from other drop tests of large ribbon parachutes are also compared with the Solid Rocket Booster parachute performance characteristics. Parameters assessed include full open terminal drag coefficients, reefed drag area, opening characteristics, clustering effects, and forebody interference.

  9. The Effect of Booster Seat Use on Pediatric Injuries in Motor Vehicle Frontal Crashes.

    PubMed

    Caskey, Sean; Hammond, Joshua; Peck, Jeffery; Sardelli, Matthew; Atkinson, Theresa

    2018-04-20

    Motor vehicle crashes are a significant source of pediatric mortality and morbidity. Studies indicate that booster seats significantly improve seat belt fit for children who have not attained a height of 145 cm (4' 9"). This study examined injuries occurring in booster age children up to age 12, as the majority of children do not attain 145 cm until this age. The purpose of the study was to identify differences in injuries due to the type of restraint used, with attention to musculoskeletal injuries. Vehicle and occupant data were obtained from a publically available statistical sample of tow-away crashes. Frontal crashes over an 8-year period were examined. A data set of cases was created involving children ages 5 to 12 years who were unrestrained, restrained using the vehicle's lap and shoulder belt, and restrained using a booster seat with the vehicle's lap and shoulder seat belt. Injury severity, frequency, and patterns of distribution were compared. Unrestrained children experienced moderate to severe injuries 3.8 to 19 times more frequently than children using restraints. There were more injuries to the head and face in unrestrained versus restrained children, but the head and face was the most frequently injured region for all groups. There were no serious cervical spine injuries reported for any group. Lower extremity fractures were not observed in booster seat users but occurred at similar rates in both unrestrained and seat belt restrained children. These fractures occurred in older children who were involved in more severe crashes. Unrestrained children were more likely to experience moderate and severe injuries than restrained children. The data sample suggests that booster use may reduce the risk of extremity fracture, as there were no extremity fractures in children restrained with booster seats. This work provides evidence for the efficacy of booster use for preventing orthopaedic injury in children. This evidence can be used to inform parents

  10. Magnetic booster fast ignition macron accelerator

    NASA Astrophysics Data System (ADS)

    Winterberg, F.

    2006-11-01

    A new fast ignition scheme was recently proposed where the ignition is done by the impact of a small solid projectile accelerated to velocities in excess of 108cm/s, with the acceleration done in two steps: first, by laser ablation of a flyer plate, and second by injecting the flyer plate into a conical duct. The two principal difficulties of this scheme are as follows: first, the required large mass ratio for the laser ablation rocket propelled flyer plate, and second, the Rayleigh-Taylor instability of the flyer plate during its implosive compression in the conical duct. To overcome these difficulties, it is suggested to accelerate a projectile by a magnetic fusion booster stage, made up of a dense, wall-confined magnetized plasma brought to thermonuclear temperatures. After ignition, this plasma undergoes a thermonuclear excursion greatly increasing its pressure, resulting in the explosion of a weakened segment of the wall, with the segment becoming a fast moving projectile. The maximum velocity this projectile can reach is the velocity of sound of the booster stage plasma, which at a temperature of 108K is of the order 108cm/s.

  11. LOGARITHMIC AMPLIFIER

    DOEpatents

    Wade, E.J.; Stone, R.S.

    1959-03-10

    Electronic,amplifier circuits, especially a logai-ithmic amplifier characterizxed by its greatly improved strability are discussed. According to the in ention, means are provided to feed bach the output valtagee to a diode in the amplifier input circuit, the diode being utilized to produce the logarithmic characteristics. The diode is tics, The diode isition therewith and having its filament operated from thc same source s the filament of the logarithmic diode. A bias current of relatively large value compareii with the signal current is continuously passed through the compiting dioie to render the diode insensitivy to variations in the signal current. by this odes kdu to variaelled, so that the stability of the amlifier will be unimpaired.

  12. Space shuttle abort separation pressure investigation. Volume 1, Part A: Booster data at Mach 5

    NASA Technical Reports Server (NTRS)

    Trimmer, L. L.; Love, D. A.; Rampy, J. M.; Decker, J. P.; Blackwell, K. L.; Strike, W. T.

    1972-01-01

    Pressure data obtained from a joint Langley Research Center (LaRC)/Marshall Space Flight Center (MSFC) Space Shuttle about stage separation wind tunnel test are presented. The .00556 scale models of the McDonnell-Douglas orbiter and booster configurations were tested in proximity in Tunnel A of the Von Karman Facility (VKF), Arnold Engineering Development Center (AEDC). Mach numbers were 5.0, 3.0, and 2.0 and nominal Reynolds numbers were 1.09, 1.60, and 1.74 million per foot, respectively. Pressure data were obtained for the booster upper surface and orbiter lower surface at angles of attack of -10 deg, -5, 0, 5, and 10 deg for zero degrees sideslip. The models were tested at incidence angles of 0 and 5 deg for several separation distances and power conditions. Plug nozzles utilizing air were used to simulate booster and orbiter plumes at various altitudes along a nominal ascent trajectory. Powered conditions were 100, 50, and 0 percent of full power for the orbiter and 100, 50 and 0 percent of full power for the booster. Data were also obtained with the booster canard off in close proximity.

  13. State Machine Modeling of the Space Launch System Solid Rocket Boosters

    NASA Technical Reports Server (NTRS)

    Harris, Joshua A.; Patterson-Hine, Ann

    2013-01-01

    The Space Launch System is a Shuttle-derived heavy-lift vehicle currently in development to serve as NASA's premiere launch vehicle for space exploration. The Space Launch System is a multistage rocket with two Solid Rocket Boosters and multiple payloads, including the Multi-Purpose Crew Vehicle. Planned Space Launch System destinations include near-Earth asteroids, the Moon, Mars, and Lagrange points. The Space Launch System is a complex system with many subsystems, requiring considerable systems engineering and integration. To this end, state machine analysis offers a method to support engineering and operational e orts, identify and avert undesirable or potentially hazardous system states, and evaluate system requirements. Finite State Machines model a system as a finite number of states, with transitions between states controlled by state-based and event-based logic. State machines are a useful tool for understanding complex system behaviors and evaluating "what-if" scenarios. This work contributes to a state machine model of the Space Launch System developed at NASA Ames Research Center. The Space Launch System Solid Rocket Booster avionics and ignition subsystems are modeled using MATLAB/Stateflow software. This model is integrated into a larger model of Space Launch System avionics used for verification and validation of Space Launch System operating procedures and design requirements. This includes testing both nominal and o -nominal system states and command sequences.

  14. Radiofrequency amplifier based on a dc superconducting quantum interference device

    DOEpatents

    Hilbert, C.; Martinis, J.M.; Clarke, J.

    1984-04-27

    A low noise radiofrequency amplifer, using a dc SQUID (superconducting quantum interference device) as the input amplifying element. The dc SQUID and an input coil are maintained at superconductivity temperatures in a superconducting shield, with the input coil inductively coupled to the superconducting ring of the dc SQUID. A radiofrequency signal from outside the shield is applied to the input coil, and an amplified radiofrequency signal is developed across the dc SQUID ring and transmitted to exteriorly of the shield. A power gain of 19.5 +- 0.5 dB has been achieved with a noise temperature of 1.0 +- 0.4 K at a frequency of 100 MHz.

  15. Expendable second stage reusable space shuttle booster. Volume 4: Detail mass properties data

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Mass properties data are presented to describe the characteristics of an expendable second stage with a reusable space shuttle booster. The final mass characteristics of the vehicle configurations for three specified payloads are presented in terms of weight, center of gravity, and mass moments of inertia. Three basic subjects are the integrated vehicle system, the expendable second stage, and the booster modifications.

  16. Tunable multi-wavelength fiber lasers based on an Opto-VLSI processor and optical amplifiers.

    PubMed

    Xiao, Feng; Alameh, Kamal; Lee, Yong Tak

    2009-12-07

    A multi-wavelength tunable fiber laser based on the use of an Opto-VLSI processor in conjunction with different optical amplifiers is proposed and experimentally demonstrated. The Opto-VLSI processor can simultaneously select any part of the gain spectrum from each optical amplifier into its associated fiber ring, leading to a multiport tunable fiber laser source. We experimentally demonstrate a 3-port tunable fiber laser source, where each output wavelength of each port can independently be tuned within the C-band with a wavelength step of about 0.05 nm. Experimental results demonstrate a laser linewidth as narrow as 0.05 nm and an optical side-mode-suppression-ratio (SMSR) of about 35 dB. The demonstrated three fiber lasers have excellent stability at room temperature and output power uniformity less than 0.5 dB over the whole C-band.

  17. 47 CFR 74.501 - Classes of aural broadcast auxiliary stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... their co-owned FM booster stations, between noncommercial educational FM radio stations and their co... microwave booster station. A fixed station in the broadcast auxiliary service that receives and amplifies...

  18. 47 CFR 74.501 - Classes of aural broadcast auxiliary stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... their co-owned FM booster stations, between noncommercial educational FM radio stations and their co... microwave booster station. A fixed station in the broadcast auxiliary service that receives and amplifies...

  19. 47 CFR 74.501 - Classes of aural broadcast auxiliary stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... their co-owned FM booster stations, between noncommercial educational FM radio stations and their co... microwave booster station. A fixed station in the broadcast auxiliary service that receives and amplifies...

  20. 47 CFR 74.501 - Classes of aural broadcast auxiliary stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... their co-owned FM booster stations, between noncommercial educational FM radio stations and their co... microwave booster station. A fixed station in the broadcast auxiliary service that receives and amplifies...

  1. Anti-pertussis antibody kinetics following DTaP-IPV booster vaccination in Norwegian children 7-8 years of age.

    PubMed

    Aase, Audun; Herstad, Tove Karin; Jørgensen, Silje Bakken; Leegaard, Truls Michael; Berbers, Guy; Steinbakk, Martin; Aaberge, Ingeborg

    2014-10-14

    At the age of 7-8 years a booster of diphtheria, tetanus, acellular pertussis and polio vaccine is recommended for children in Norway. In this cross-sectional study we have analysed the antibody levels against pertussis vaccine antigens in sera from 498 children aged 6-12 years. The purposes of this study were to investigate the duration of the booster response against the pertussis vaccine antigens pertussis toxin (PT) and filamentous haemagglutinin (FHA); to determine the presence of high levels of pertussis antibodies in absence of recent vaccination; and to analyse how booster immunisation may interfere with the serological pertussis diagnostics. Prior to the booster the IgG antibody levels against PT revealed a geometric mean of 7.3IU/ml. After the booster the geometric mean peak anti-PT IgG response reached to 45.6IU/ml, followed by a steady decline in antibody levels over the next few years. The IgG anti-FHA levels followed the anti-PT IgG profiles. Three years after the booster the geometric mean IgG levels were only slightly above pre-booster levels. Prior to the booster 44% of the sera contained ≤5IU/ml of anti-PT IgG compared to18% 3 years after and 30% 4 years after the booster. When recently vaccinated children were excluded, 6.2% of the children had anti-PT IgG levels above 50IU/ml which may indicate pertussis infection within the last 2 years. This study indicates that the currently used acellular pertussis vaccines induce moderate immune responses to the pertussis antigens and that the antibodies wane within few years after the booster. This lack of sustained immune response may partly be responsible for the increased number of pertussis cases observed in this age group during the last years. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  2. ULTRA-STABILIZED D. C. AMPLIFIER

    DOEpatents

    Hartwig, E.C.; Kuenning, R.W.; Acker, R.C.

    1959-02-17

    An improved circuit is described for stabilizing the drift and minimizing the noise and hum level of d-c amplifiers so that the output voltage will be zero when the input is zero. In its detailed aspects, the disclosed circuit incorporates a d-c amplifier having a signal input, a second input, and an output circuit coupled back to the first input of the amplifier through inverse feedback means. An electronically driven chopper having a pair of fixed contacts and a moveable contact alternately connects the two inputs of a difference amplifier to the signal input. The A. E. error signal produced in the difference amplifier is amplified, rectified, and applied to the second input of the amplifier as the d-c stabilizing voltage.

  3. NASA's B-52 mother ship carries the X-43A and its booster rocket on a captive carry flight Jan. 26, 2004

    NASA Image and Video Library

    2004-01-26

    NASA's historic B-52 mother ship carried the X-43A and its Pegasus booster rocket on a captive carry flight from Edwards Air Force Base Jan. 26, 2004. The X-43A and its booster remained mated to the B-52 throughout the two-hour flight, intended to check its readiness for launch. The hydrogen-fueled aircraft is autonomous and has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  4. Control techniques to improve Space Shuttle solid rocket booster separation

    NASA Technical Reports Server (NTRS)

    Tomlin, D. D.

    1983-01-01

    The present Space Shuttle's control system does not prevent the Orbiter's main engines from being in gimbal positions that are adverse to solid rocket booster separation. By eliminating the attitude error and attitude rate feedback just prior to solid rocket booster separation, the detrimental effects of the Orbiter's main engines can be reduced. In addition, if angular acceleration feedback is applied, the gimbal torques produced by the Orbiter's engines can reduce the detrimental effects of the aerodynamic torques. This paper develops these control techniques and compares the separation capability of the developed control systems. Currently with the worst case initial conditions and each Shuttle system dispersion aligned in the worst direction (which is more conservative than will be experienced in flight), the solid rocket booster has an interference with the Shuttle's external tank of 30 in. Elimination of the attitude error and attitude rate feedback reduces that interference to 19 in. Substitution of angular acceleration feedback reduces the interference to 6 in. The two latter interferences can be eliminated by atess conservative analysis techniques, that is, by using a root sum square of the system dispersions.

  5. Spacecraft and their Boosters. Aerospace Education I.

    ERIC Educational Resources Information Center

    Coard, E. A.

    This book, one in the series on Aerospace Education I, provides a description of some of the discoveries that spacecraft have made possible and of the experience that American astronauts have had in piloting spacecraft. The basic principles behind the operation of spacecraft and their boosters are explained. Descriptions are also included on…

  6. A Mathematical Model of a Simple Amplifier Using a Ferroelectric Transistor

    NASA Technical Reports Server (NTRS)

    Sayyah, Rana; Hunt, Mitchell; MacLeod, Todd C.; Ho, Fat D.

    2009-01-01

    This paper presents a mathematical model characterizing the behavior of a simple amplifier using a FeFET. The model is based on empirical data and incorporates several variables that affect the output, including frequency, load resistance, and gate-to-source voltage. Since the amplifier is the basis of many circuit configurations, a mathematical model that describes the behavior of a FeFET-based amplifier will help in the integration of FeFETs into many other circuits.

  7. Development of the beam extraction synchronization system at the Fermilab Booster

    DOE PAGES

    Seiya, K.; Chaurize, S.; Drennan, C. C.; ...

    2015-07-28

    The new beam extraction synchronization control system called “Magnetic Cogging” was developed at the Fermilab Booster and it replaces a system called “RF Cogging” as part of the Proton Improvement Plan (PIP). [1] The flux throughput goal for the PIP is 2.2×10 17 protons per hour, which is double the present flux. Thus, the flux increase will be accomplished by doubling the number of beam cycles which, in turn, will double the beam loss in the Booster accelerator if nothing else is done.

  8. [Preparation of O/W ginseng saponins-based nanoemulsion and its amplified immune response].

    PubMed

    Cao, Fahao; Ouyang, Wuqing; Wang, Yanping

    2010-02-01

    To prepare an O/W ginseng saponins-based nanoemulsion and investigate its amplified immune response. The formulation of ginseng saponins-based nanoemulsion was optimized via the range of nanoemulsion zone in phase diagrams and the solubility of ginseng saponins. Its physicochemical properties were investigated, including morphology, particle size distribution, pH, viscosity and stability. Ginseng saponins-based nanoemulsion as adjuvant was co-administrated with a model antigen ovalbumin (OVA) in mice. Two weeks after the boosting, the serum levels of OVA-specific antibody and its isotypes were determined. The optimized ginseng saponins-based nanoemulsion formulation consisted of ginseng saponins, IPM, Cremophor RH 40, glycerol and water (with the weight ratio of 2 : 4 : 17.8 : 17.8 : 58.4), which was a light yellow fluid. The shape of droplets was spherical under transmission electron microscopy with an average diameter of 72.20 nm and a polydispersity index of 0.052. The viscosity and pH value of it were 4.20 s and 6.02, respectively. And it showed good stability. When co-administered with OVA, no obvious side effects were observed in the mice immunized with ginseng saponin-based nanoemulsion. The serum levels of IgG, IgG1 and IgG2a antibody in the group of ginseng saponin-based nanoemulsion immunized mice was significantly increased compared to the groups of OVA and the saline solution of ginseng saponin. Compared with the adjuvant aluminium hydroxide, the serum levels of IgG and IgG1 antibodys in the groups of ginseng saponins-based nanoemulsion had no significant difference, but the level of IgG2a was obviously higher. ginseng saponin-based nanoemulsion could amplify the Th1 and Th2 immune responses, and can be used as the vaccine adjuvant.

  9. First Test Results of the bERLinPro 2-cell Booster Cavities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burrill, Andrew; Anders, W.; Frahm, A.

    2015-09-01

    The bERLinPro Energy Recovery Linac (ERL) is currently being built at Helmholtz-Zentrum Berlin in order to study the physics of operating a high-current, a 100 mA, 50 MeV ERL utilizing all SRF cavity technology. This machine will utilize three unique SRF cryomodules for the photoinjector, booster and linac cryomodules respectively. The focus of this paper will be on the cavities contained within the booster cryomodule. Here there will be three 2-cell SRF cavities, based on the original design by Cornell University, but optimized to meet the needs of the project. All of the cavity fabrication, processing and testing was carriedmore » out at Jefferson Laboratory, where 4 cavities were produced, and the 3 cavities with the best RF performance were fitted with helium vessels for installation in the cryomodule. This paper will report on the test results of the cavities as measured in the vertical testing dewar at JLab after fabrication and again after outfitting with the helium vessels.« less

  10. An analysis of booster tone noise using a time-linearized Navier-Stokes solver

    NASA Astrophysics Data System (ADS)

    Wukie, Nathan A.

    This thesis details a computational investigation of tone noise generated from a booster(low-pressure compressor) in a fan test rig. The computational study consisted of sets of time-linearized Navier-Stokes simulations in the booster region to investigate the blade-wake interactions that act as the primary noise-generating mechanism for the booster blade-passing frequency and harmonics. An acoustic test database existed with data at several operating points for the fan test rig that was used to compare against the predicted noise data from the computational study. It is shown that the computational methodology is able to capture trends in sound power for the 1st and 2nd booster tones along the operating line for the rig. It is also shown that the computational study underpredicts one of the tones at low power and is not able to capture a peak in the data at the Cutback condition. Further investigation of this type is warranted to quantify the source of discrepancies between the computational and experimental data as the reflected transmisison of sound off the fan through the bypass duct was not accounted for in this study.

  11. Delta II ICESat-2 Booster Transport

    NASA Image and Video Library

    2018-04-17

    At Vandenberg Air Force Base in California, on Tuesday, April 17, 2018, a United Launch Alliance (ULA) Delta II booster is transported to Space Launch Complex-2 where it will launch NASA's Ice, Cloud and land Elevation Satellite-2, or ICESat-2, satellite. This will be the last flight for the venerable Delta II rocket. ICESat-2, which is being built and tested by Orbital ATK in Gilbert, Arizona, will carry a single instrument called the Advanced Topographic Laser Altimeter System, or ATLAS. The ATLAS instrument is being built and tested at NASA’s Goddard Space Flight Center in Greenbelt Maryland. Once in orbit, the satellite is designed to measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. ICESat-2 will help scientists investigate why, and how much, Earth’s frozen and icy areas, called the cryosphere, are changing.

  12. Delta II ICESat-2 Booster Transport

    NASA Image and Video Library

    2018-04-17

    At Vandenberg Air Force Base in California, on Tuesday, April 17, 2018, a United Launch Alliance (ULA) Delta II booster arrives at Space Launch Complex-2 where it will launch NASA's Ice, Cloud and land Elevation Satellite-2, or ICESat-2, satellite. This will be the last flight for the venerable Delta II rocket. ICESat-2, which is being built and tested by Orbital ATK in Gilbert, Arizona, will carry a single instrument called the Advanced Topographic Laser Altimeter System, or ATLAS. The ATLAS instrument is being built and tested at NASA’s Goddard Space Flight Center in Greenbelt Maryland. Once in orbit, the satellite is designed to measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. ICESat-2 will help scientists investigate why, and how much, Earth’s frozen and icy areas, called the cryosphere, are changing.

  13. Self-amplifying mRNA vaccines.

    PubMed

    Brito, Luis A; Kommareddy, Sushma; Maione, Domenico; Uematsu, Yasushi; Giovani, Cinzia; Berlanda Scorza, Francesco; Otten, Gillis R; Yu, Dong; Mandl, Christian W; Mason, Peter W; Dormitzer, Philip R; Ulmer, Jeffrey B; Geall, Andrew J

    2015-01-01

    This chapter provides a brief introduction to nucleic acid-based vaccines and recent research in developing self-amplifying mRNA vaccines. These vaccines promise the flexibility of plasmid DNA vaccines with enhanced immunogenicity and safety. The key to realizing the full potential of these vaccines is efficient delivery of nucleic acid to the cytoplasm of a cell, where it can amplify and express the encoded antigenic protein. The hydrophilicity and strong net negative charge of RNA impedes cellular uptake. To overcome this limitation, electrostatic complexation with cationic lipids or polymers and physical delivery using electroporation or ballistic particles to improve cellular uptake has been evaluated. This chapter highlights the rapid progress made in using nonviral delivery systems for RNA-based vaccines. Initial preclinical testing of self-amplifying mRNA vaccines has shown nonviral delivery to be capable of producing potent and robust innate and adaptive immune responses in small animals and nonhuman primates. Historically, the prospect of developing mRNA vaccines was uncertain due to concerns of mRNA instability and the feasibility of large-scale manufacturing. Today, these issues are no longer perceived as barriers in the widespread implementation of the technology. Currently, nonamplifying mRNA vaccines are under investigation in human clinical trials and can be produced at a sufficient quantity and quality to meet regulatory requirements. If the encouraging preclinical data with self-amplifying mRNA vaccines are matched by equivalently positive immunogenicity, potency, and tolerability in human trials, this platform could establish nucleic acid vaccines as a versatile new tool for human immunization. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Efficacy and Duration of Immunity after Yellow Fever Vaccination: Systematic Review on the Need for a Booster Every 10 Years

    PubMed Central

    Gotuzzo, Eduardo; Yactayo, Sergio; Córdova, Erika

    2013-01-01

    Current regulations stipulate a yellow fever (YF) booster every 10 years. We conducted a systematic review of the protective efficacy and duration of immunity of YF vaccine in residents of disease-endemic areas and in travelers to assess the need for a booster in these two settings and in selected populations (human immunodeficiency virus–infected persons, infants, children, pregnant women, and severely malnourished persons). Thirty-six studies and 22 reports were included. We identified 12 studies of immunogenicity, 8 of duration of immunity, 8 of vaccine response in infants and children, 7 of human-immunodeficiency virus–infected persons, 2 of pregnant women, and 1 of severely malnourished children. Based on currently available data, a single dose of YF vaccine is highly immunogenic and confers sustained life-long protective immunity against YF. Therefore, a booster dose of YF vaccine is not needed. Special considerations for selected populations are detailed. PMID:24006295

  15. DISTRIBUTED AMPLIFIER INCORPORATING FEEDBACK

    DOEpatents

    Bell, P.R. Jr.

    1958-10-21

    An improved distributed amplifier system employing feedback for stabilization is presented. In accordance with the disclosed invention, a signal to be amplified is applled to one end of a suitable terminated grid transmission line. At intervals along the transmission line, the signal is fed to stable, resistance-capacitance coupled amplifiers incorporating feedback loops therein. The output current from each amplifier is passed through an additional tube to minimize the electrostatic capacitance between the tube elements of the last stage of the amplifier, and fed to appropriate points on an output transmission line, similar to the grid line, but terminated at the opposite (input) end. The output taken from the unterminated end of the plate transmission line is proportional to the input voltage impressed upon the grid line.

  16. 75 FR 68664 - Federal Motor Vehicle Safety Standards; Child Restraint Systems; Booster Seat Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    ... early graduation from booster seats to lap and shoulder belts. Estimates are computed by double-pair... 3-4-year-olds there is evidence of increased risk of injury when restrained in booster seats rather.... Among 4-8-year-olds there is strong evidence of increased risk of injury when restrained by lap and...

  17. [Mathematic modeling for prediction of waning immunity and timing of booster doses].

    PubMed

    Matuo, Fujio; Okada, Kenji

    2008-10-01

    Under an environment that a vaccination rate is low and an infectious disease is prevalent, it is thought that most vaccinee got additional immunity by natural infection. On the other hand, in the area where the incidence of disease has been reduced by high rate vaccination, it is also decreased the chance of additional immunity by natural infection. Therefore susceptible individuals are increased because of the waning immunity. In the community where a vaccination rate is high, it may be necessary to consider the booster vaccination for adolescent and adult even if one completed the primary vaccinations. It may also be important to explore the timing of booster dose. In this paper, we attempt to give a comprehensive explanation of mathematical model for predicting the antibody duration, and we introduce the role of mathematical model on a consideration to the need and timing of booster doses after the primary series.

  18. Humoral and Cell-Mediated Immune Responses to Alternate Booster Schedules of Anthrax Vaccine Adsorbed in Humans

    PubMed Central

    Sabourin, Carol L.; Schiffer, Jarad M.; Niemuth, Nancy A.; Semenova, Vera A.; Li, Han; Rudge, Thomas L.; Brys, April M.; Mittler, Robert S.; Ibegbu, Chris C.; Wrammert, Jens; Ahmed, Rafi; Parker, Scott D.; Babcock, Janiine; Keitel, Wendy; Poland, Gregory A.; Keyserling, Harry L.; El Sahly, Hana; Jacobson, Robert M.; Marano, Nina; Plikaytis, Brian D.; Wright, Jennifer G.

    2016-01-01

    Protective antigen (PA)-specific antibody and cell-mediated immune (CMI) responses to annual and alternate booster schedules of anthrax vaccine adsorbed (AVA; BioThrax) were characterized in humans over 43 months. Study participants received 1 of 6 vaccination schedules: a 3-dose intramuscular (IM) priming series (0, 1, and 6 months) with a single booster at 42 months (4-IM); 3-dose IM priming with boosters at 18 and 42 months (5-IM); 3-dose IM priming with boosters at 12, 18, 30, and 42 months (7-IM); the 1970 licensed priming series of 6 doses (0, 0.5, 1, 6, 12, and 18 months) and two annual boosters (30 and 42 months) administered either subcutaneously (SQ) (8-SQ) or IM (8-IM); or saline placebo control at all eight time points. Antibody response profiles included serum anti-PA IgG levels, subclass distributions, avidity, and lethal toxin neutralization activity (TNA). CMI profiles included frequencies of gamma interferon (IFN-γ)- and interleukin 4 (IL-4)-secreting cells and memory B cells (MBCs), lymphocyte stimulation indices (SI), and induction of IFN-γ, IL-2, IL-4, IL-6, IL-1β, and tumor necrosis factor alpha (TNF-α) mRNA. All active schedules elicited high-avidity PA-specific IgG, TNA, MBCs, and T cell responses with a mixed Th1-Th2 profile and Th2 dominance. Anti-PA IgG and TNA were highly correlated (e.g., month 7, r2 = 0.86, P < 0.0001, log10 transformed) and declined in the absence of boosters. Boosters administered IM generated the highest antibody responses. Increasing time intervals between boosters generated antibody responses that were faster than and superior to those obtained with the final month 42 vaccination. CMI responses to the 3-dose IM priming remained elevated up to 43 months. (This study has been registered at ClinicalTrials.gov under registration no. NCT00119067.) PMID:26865594

  19. Fred Hutchinson Cancer Research Center (FHCRC1): Functional Landscape of the Human Kinome in MYCN Amplified and Non-amplified Neuroblastoma | Office of Cancer Genomics

    Cancer.gov

    In order to identify candidate drugs targets that exhibit lethality only in the context of MYCN amplification, we carried out a set of siRNA screens focused on the kinome, targeting ~713 kinases, utilizing human neuroblastoma cells lines with or without MYCN amplification. The neuroblastoma cell lines were: SK-N-BE2 (MYCN amplified) and SK-N-AS (non-amplified).  The kinase Hits for the MYCN amplified cell line were selected using a combination of their differential activity when compared to the non-MYCN amplified cells and also ranked by P-values, based on the replicates.

  20. Fred Hutchinson Cancer Research Center (FHCRC-1): Functional Landscape of the Human Kinome in MYCN Amplified and Non-amplified Neuroblastoma | Office of Cancer Genomics

    Cancer.gov

    In order to identify candidate drugs targets that exhibit lethality only in the context of MYCN amplification, we carried out a set of siRNA screens focused on the kinome, targeting ~713 kinases, utilizing human neuroblastoma cells lines with or without MYCN amplification. The neuroblastoma cell lines were: SK-N-BE2 (MYCN amplified) and SK-N-AS (non-amplified). The kinase Hits for the MYCN amplified cell line were selected using a combination of their differential activity when compared to the non-MYCN amplified cells and also ranked by P-values, based on the replicates.