Budget Update: June 3, 2010. Report 10-09
ERIC Educational Resources Information Center
Woolfork, Kevin
2010-01-01
On May 14, Governor Arnold Schwarzenegger released the May Revision to the proposed budget for the current year (2009-10) and budget year (2010-11). State finances have continued a three-year decline, with anticipated General Fund spending of $83 billion, their lowest in six years. To address the budget shortfall, the Governor proposes major…
Continuation Power Flow with Variable-Step Variable-Order Nonlinear Predictor
NASA Astrophysics Data System (ADS)
Kojima, Takayuki; Mori, Hiroyuki
This paper proposes a new continuation power flow calculation method for drawing a P-V curve in power systems. The continuation power flow calculation successively evaluates power flow solutions through changing a specified value of the power flow calculation. In recent years, power system operators are quite concerned with voltage instability due to the appearance of deregulated and competitive power markets. The continuation power flow calculation plays an important role to understand the load characteristics in a sense of static voltage instability. In this paper, a new continuation power flow with a variable-step variable-order (VSVO) nonlinear predictor is proposed. The proposed method evaluates optimal predicted points confirming with the feature of P-V curves. The proposed method is successfully applied to IEEE 118-bus and IEEE 300-bus systems.
Bilingual Program Application for Continuation Proposal: Compton Unified School District.
ERIC Educational Resources Information Center
Compton City Schools, CA.
This document contains the continuation proposal for the fourth grade Compton bilingual education program. A review of the third year is included with details on process evaluation, project personnel and duties, new vocabulary developed by the project for lexical references, and inservice training of teachers. Information concerning the proposed…
The Development of a Continuing Education Program for Mid-Career Professionals.
ERIC Educational Resources Information Center
Gunderson, Norman O.
The Master's Degree Program in Cybernetic Systems was proposed a decade ago as an interdisciplinary problem-solving oriented educational effort. Implemented seven years ago, it has developed into a successful continuing education vehicle for mid-career professionals. Those proposing the program recognized that without guidelines to follow, it must…
Geophysics Funding Healthy in FY 1986 Federal Budget
NASA Astrophysics Data System (ADS)
Richman, Barbara T.; Robb, David W.
Continued support for many geophysics projects is part of the fiscal year (FY) 1986 budget proposal that President Ronald Reagan sent to Congress earlier this month. Unlike many other programs that took deep cuts or were eliminated, overall funding for science held steady in the proposed budget. This budget proposal, however, did not offer the large increases that had been proposed for FY 1985 (Eos, February 14, 1984, p. 49). Figure 1 shows the trend for science outlays during the past several years.
76 FR 15039 - Commercial Space Transportation Grants Program
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-18
... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation... proposals for the Commercial Space Transportation Grant Program. SUMMARY: This notice solicits Fiscal Year (FY) 2011 grant proposals to continue the development of a Commercial Space Transportation...
77 FR 14462 - Space Transportation Infrastructure Matching Grants Program
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-09
... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Space Transportation Infrastructure... grant proposals for the Space Transportation Infrastructure Matching Grants Program. SUMMARY: This notice solicits Fiscal Year (FY) 2012 grant proposals to continue the development of a Commercial Space...
NASA Technical Reports Server (NTRS)
Elliot, James
2005-01-01
Below is the annual progress report (through 2005-01-31) on NASA Grant NNG04GF25G. It is organized according to: (I) Accomplishments in the last year against the objectives laid out in the original proposal; (II) The current status of the research; (III) The work to go in the next year; (IV) Publications. Since this program is a continuation of the occultation work supported in a predecessor grant, the "Accomplishments" section lists all the tasks written into the proposal (in June 2003) through the end of the first year of the new grant.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-01
...EPA and NHTSA, on behalf of the Department of Transportation, are issuing this joint proposal to further reduce greenhouse gas emissions and improve fuel economy for light-duty vehicles for model years 2017-2025. This proposal extends the National Program beyond the greenhouse gas and corporate average fuel economy standards set for model years 2012-2016. On May 21, 2010, President Obama issued a Presidential Memorandum requesting that NHTSA and EPA develop through notice and comment rulemaking a coordinated National Program to reduce greenhouse gas emissions of light-duty vehicles for model years 2017- 2025. This proposal, consistent with the President's request, responds to the country's critical need to address global climate change and to reduce oil consumption. NHTSA is proposing Corporate Average Fuel Economy standards under the Energy Policy and Conservation Act, as amended by the Energy Independence and Security Act, and EPA is proposing greenhouse gas emissions standards under the Clean Air Act. These standards apply to passenger cars, light-duty trucks, and medium- duty passenger vehicles, and represent a continued harmonized and consistent National Program. Under the National Program for model years 2017-2025, automobile manufacturers would be able to continue building a single light-duty national fleet that satisfies all requirements under both programs while ensuring that consumers still have a full range of vehicle choices. EPA is also proposing a minor change to the regulations applicable to MY 2012-2016, with respect to air conditioner performance and measurement of nitrous oxides.
NASA Technical Reports Server (NTRS)
Kopardekar, Parimal Hemchandra
2016-01-01
Just a year ago we laid out the UTM challenges and NASA's proposed solutions. During the past year NASA's goal continues to be to conduct research, development and testing to identify airspace operations requirements to enable large-scale visual and beyond visual line-of-sight UAS operations in the low-altitude airspace. Significant progress has been made, and NASA is continuing to move forward.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-27
... DEPARTMENT OF COMMERCE Census Bureau Proposed Information Collection; Comment Request; Survey of.... SUPPLEMENTARY INFORMATION: I. Abstract The Census Bureau conducts the SIPP, which is a household-based survey designed as a continuous series of national panels. New panels are introduced every few years with each...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-20
... DEPARTMENT OF COMMERCE Census Bureau Proposed Information Collection; Comment Request; Survey of.... SUPPLEMENTARY INFORMATION: I. Abstract The Census Bureau conducts the SIPP, which is a household-based survey designed as a continuous series of national panels. New panels are introduced every few years with each...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-21
... DEPARTMENT OF COMMERCE Census Bureau Proposed Information Collection; Comment Request; Survey of.... SUPPLEMENTARY INFORMATION: I. Abstract The Census Bureau conducts the SIPP, which is a household-based survey designed as a continuous series of national panels. New panels are introduced every few years with each...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-15
... Information Collection: Comment Request Office of Sustainable Housing Communities Progress Report Template... subject proposal. The Department of Defense and Full-Year Continuing Appropriations Act, 2011 (Pub. L. 112... be sent to: Reports Liaison Officer, Department of Housing and Urban Development, 451 7th Street SW...
Our NASA is strong on This Week @NASA – February 12, 2016
2016-02-12
During his Feb. 9 State of NASA speech at Langley Research Center in Hampton, Va, Administrator Charles Bolden characterized President Obama’s $19 billion Fiscal Year 2017 budget proposal for NASA as a vote of confidence and an indication of the agency’s strength. Bolden noted that the investments in the FY2017 budget proposal will empower NASA to continue to work with partners both in and out of government to develop the technologies that drive exploration – to build an even stronger future in which NASA continues reaching for new heights for the benefit of all humankind. Also, Space station one-year crew update, Increased land water slows sea level rise, Gravitational waves detected, and more!
77 FR 57194 - Proposed Collection; Comment Request for Form 8611
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-17
... proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995... credit against their income tax. If the property is disposed of or if it fails to meet certain requirements over a 15-year compliance period and a bond is not posted, the owner must recapture on Form 8611...
ERIC Educational Resources Information Center
Lindsay, Hilary
2016-01-01
This paper explores literature relating to continuing professional development (CPD) and lifelong learning to develop an understanding of how the learning landscape has evolved in recent years, both in the accountancy profession and more widely. Three different perspectives on learning are drawn together and this synthesis is used to develop a…
78 FR 9927 - Agency Information Collection Activities: Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-12
... the past several years, we received numerous suggestions to further revise our process to continue to... contracts. These contracts are on 3-year cycles. To better administer the program, CMS is requiring...: 36; Total Annual Hours: 108. (For policy questions regarding this collection contact Benjamin...
Ongoing Mars Missions: Extended Mission Plans
NASA Astrophysics Data System (ADS)
Zurek, Richard; Diniega, Serina; Crisp, Joy; Fraeman, Abigail; Golombek, Matt; Jakosky, Bruce; Plaut, Jeff; Senske, David A.; Tamppari, Leslie; Thompson, Thomas W.; Vasavada, Ashwin R.
2016-10-01
Many key scientific discoveries in planetary science have been made during extended missions. This is certainly true for the Mars missions both in orbit and on the planet's surface. Every two years, ongoing NASA planetary missions propose investigations for the next two years. This year, as part of the 2016 Planetary Sciences Division (PSD) Mission Senior Review, the Mars Odyssey (ODY) orbiter project submitted a proposal for its 7th extended mission, the Mars Exploration Rover (MER-B) Opportunity submitted for its 10th, the Mars Reconnaissance Orbiter (MRO) for its 4th, and the Mars Science Laboratory (MSL) Curiosity rover and the Mars Atmosphere and Volatile Evolution (MVN) orbiter for their 2nd extended missions, respectively. Continued US participation in the ongoing Mars Express Mission (MEX) was also proposed. These missions arrived at Mars in 2001, 2004, 2006, 2012, 2014, and 2003, respectively. Highlights of proposed activities include systematic observations of the surface and atmosphere in twilight (early morning and late evening), building on a 13-year record of global mapping (ODY); exploration of a crater rim gully and interior of Endeavour Crater, while continuing to test what can and cannot be seen from orbit (MER-B); refocused observations of ancient aqueous deposits and polar cap interiors, while adding a 6th Mars year of change detection in the atmosphere and the surface (MRO); exploration and sampling by a rover of mineralogically diverse strata of Mt. Sharp and of atmospheric methane in Gale Crater (MSL); and further characterization of atmospheric escape under different solar conditions (MVN). As proposed, these activities follow up on previous discoveries (e.g., recurring slope lineae, habitable environments), while expanding spatial and temporal coverage to guide new detailed observations. An independent review panel evaluated these proposals, met with project representatives in May, and made recommendations to NASA in June 2016. In this presentation, we will highlight the planned activities of these NASA Mars missions, as they start new chapters in their historic exploration of the dynamic and complex planet that is Mars.
77 FR 28606 - Agency Information Collection Activities: Proposed Collection: Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-15
... of both competitive programs will need to complete non-competing continuation (NCC) progress reports...-year project periods. Development Grant recipients will be required to complete one NCC to secure the...
Aeronautics Education, Research, and Industry Alliance (AERIAL) Year 2 Report and Year 3 Proposal
NASA Technical Reports Server (NTRS)
Bowen, Brent D.; Box, Richard C.; Fink, Mary M.; Gogos, Geroge; Lehrer, Henry R.; Narayanan, Ram M.; Nickerson, Jocelyn S.; Tarry, Scott E.; Vlasek, Karisa D.
2003-01-01
The Aeronautics Education, Research, and Industry Alliance (AERIAL): a comprehensive, multi-faceted NASA EPSCoR 2000 initiative, contributes to the strategic research and technology priorities of NASA while intensifying Nebraska s rapidly growing aeronautics research and development endeavors. AERIAL enables Nebraska researchers to: (a) continue strengthening their collaborative relationships with NASA Field Centers, Codes, and Enterprises; (b) increase the capacity of higher education throughout Nebraska to invigorate and expand aeronautics research; and (c) expedite the development of aeronautics-related research infrastructure and industry in the state. This report contains a summary of AERIAL's activities and accomplishments during the second year of implementation. The AERIAL Year 3 proposal is also included.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-04
... renewed Facility Operating License No. R-37, to be held by the Massachusetts Institute of Technology (MIT... Identification of the Proposed Action The proposed action would renew Facility Operating License No. R-37 for a... License No. R-37 to allow continued operation of the MITR for a period of twenty years at an increased...
ERIC Educational Resources Information Center
Kempen, M.; Steyn, G. M.
2016-01-01
A collaborative continuous professional (CPD) model was implemented and evaluated in six special schools in Gauteng, South Africa in order to support teachers in their professional capacity. The study which reports on a two year study aimed to establish the value of the CPD programme on teachers' learning, students' outcomes and whole school…
Division B Commission 5: Documentation and Astronomical Data
NASA Astrophysics Data System (ADS)
Hanisch, Robert; Wise, Michael; Ohishi, Masatoshi; Andernach, Heinz; Bishop, Marsha; Egret, Daniel; Griffin, Elizabeth; Kembhavi, Ajit; Murphy, Tara; Pasian, Fabio; Schroeder, Anja; Tody, Douglas
2016-04-01
IAU Commission 5, Documentation and Astronomical Data, continued its mission of promoting and supporting sound practices of data management, data dissemination, and data preservation over the past three years. The Commission also prepared its proposal for continuation, with some changes in emphasis, after the IAU's commission restructuring program. Below we report on the activities of the various Working Groups and the one Task Force in Commission 5.
A. Dennis Lemly; Joseph P. Skorupa
2012-01-01
This analysis examines wildlife poisoning from coal combustion waste (CCW) in the context of EPA's proposed policy that would allow continued use of surface impoundments as a disposal method. Data from 21 confirmed damage sites were evaluated, ranging from locations where historic poisoning has led to corrective actions that have greatly improved environmental...
Research in cosmic and gamma ray astrophysics: Cosmic physics portion
NASA Technical Reports Server (NTRS)
Stone, Edward C.; Mewaldt, Richard A.; Schindler, Stephen
1993-01-01
Research in particle astrophysics at the Space Radiation Laboratory (SRL) of the California Institute of Technology is supported under NASA Grant NAGW-1919. A three-year proposal for continuation of support was submitted a year ago and put into effect 1 October 1992. This report is the combined progress report and continuation application called for under the Federal Demonstration Project. Gamma-ray Astrophysics at SRL is separately supported under NAGW-1919 and will be separately summarized and proposed. This report will document progress and plans for our particle spectroscopy activities and for related data analysis, calibration, and community service activities. A bibliography and a budget will be attached as appendices. The Caltech SRL research program includes a heavy emphasis on elemental and isotopic spectroscopy of energetic particles in the cosmic radiation; in solar, interplanetary, and anomalous 'cosmic' radiation; and in planetary magnetospheres as discussed.
75 FR 78720 - Agency Information Collection Activities: Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-16
.... Proposed Project: 2011-2014 National Survey on Drug Use and Health: Methodological Field Tests (OMB No..., SAMHSA received a 3-year renewal of its generic clearance for methodological field tests. This will be a request for another renewal of the generic approval to continue methodological tests over the next 3 years...
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Select Committee on Indian Affairs.
The Senate Select Committee on Indian Affairs met to hear testimony on the proposed budget for the 1985 fiscal year, which calls for continued support of Indian self-determination by strengthening tribal governments and decreasing unnecessary Federal intrusion in reservation affairs. Discussion was primarily concerned with funding for Indian…
Asynchronous discrete control of continuous processes
NASA Astrophysics Data System (ADS)
Kaliski, M. E.; Johnson, T. L.
1984-07-01
The research during this second contract year continued to deal with the development of sound theoretical models for asynchronous systems. Two criteria served to shape the research pursued: the first, that the developed models extend and generalize previously developed research for synchronous discrete control; the second, that the models explicitly address the question of how to incorporate system transition times into themselves. The following sections of this report concisely delineate this year's work. Our original proposal for this research identified four general tasks of investigation: (1.1) Analysis of Qualitative Properties of Asynchronous Hybrid Systems; (1.2) Acceptance and Control for Asynchronous Hybrid Systems.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-13
... the amount of water for farming activities but would continue to replace water allocated for other... management practices, impacts to environmental resources such as surface water, groundwater levels, land...
Proposed NASA Budget Includes Asteroid Capture but Cuts Planetary Science and Education
NASA Astrophysics Data System (ADS)
Balcerak, Ernie
2013-04-01
The Obama administration's proposed 17.7 billion budget for NASA for fiscal year (FY) 2014 provides 105 million for several asteroid-related initiatives, including preliminary studies for a potential mission that would capture an asteroid and drag it into orbit around the Moon. The agency's total proposed budget is down slightly compared to FY 2012 (see Table ; comparisons are to FY 2012 because government agencies had been operating on a continuing resolution for 2013 and final spending levels for 2013 were not available at the time the president released his proposed 2014 budget).
A complete public archive for the Einstein IPC
NASA Technical Reports Server (NTRS)
Helfand, David J.
1993-01-01
This report documents progress made in the period 29 September 1992 and 28 September 1993, on the project described in our proposal 'A Complete Public Archive for the Einstein IPC,' which was approved under the Astrophysics Data Program last year. All of the principal first-year objectives were achieved and we expect to continue our efforts over the next two years toward the goal of transferring the entire activity to the HEASARC.
7 CFR 253.11 - Administrative funds.
Code of Federal Regulations, 2014 CFR
2014-01-01
... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... fiscal year and apportionment of funds by the Office of Management and Budget, administrative funds will... receiving administrative funds, State agencies must submit a proposed budget reflecting planned...
7 CFR 253.11 - Administrative funds.
Code of Federal Regulations, 2013 CFR
2013-01-01
... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... fiscal year and apportionment of funds by the Office of Management and Budget, administrative funds will... receiving administrative funds, State agencies must submit a proposed budget reflecting planned...
Haschke, F
1992-01-01
Effective preventive programs must be instituted early in the life of a child. The pediatrician plays an important role in preventive oral health care, because most children do not visit a dentist before 3 years of age. Fluoride therapy decreases the caries vulnerability of the tooth, oral hygiene measures are important to remove bacterial plaque, and dietary modifications reduce the number of carbohydrate exposures per day. Community water fluoridation is proposed in Austrian cities, because it continues to be the most cost-effective caries prevention measure available. As long as the population does not have access to optimally fluoridated water, dietary fluoride supplementation offers an effective alternative. The recommended dosage of fluoride supplements for children depends on the amount of fluoride present in their drinking water and on the child's age. Liquid fluoride supplements and chewable tablets are proposed for children between 0.5 and 3 years and children between 3 and 13 years, respectively. Home use topical fluorides and professionally applied topical fluorides are useful beyond 3 years of age. Teaching of oral hygiene measures should be continued in kindergarten and school. The 3-6 year-old children require parental assistance to achieve effective plaque removal. Semiannual dental visits should begin at the age of three and continue throughout childhood and adolescence. As far as the diet is concerned, the frequency of exposure to sugar appears to be the most important factor in the development of dental caries. It now appears that most sugars are nearly equally cariogenic in a pure form.
Presolar Grains as Tracers of Nebular Processes
NASA Technical Reports Server (NTRS)
Huss, Gary R.
2001-01-01
This grant provided two years of funding to investigate the abundances of presolar diamond, SiC, and graphite in primitive chondritic meteorites. The original proposal was for a three-year study, but two years of funding were awarded. The proposed work plan for the first year included preparation of acid residues for two meteorites and noble-gas measurements on those residues and residues of two other meteorites that had been previously prepared. The meteorites to be measured were Acfer 003, Adrar 214, RC075, and Axtell. In the second year, the plan called for measuring Renazzo and Murchison, and beginning chemical processing on another set of meteorites, including Murray, which were to be measured in the third year. All of the meteorites listed above have been measured and the results were presented in three abstracts. The project is continuing under follow-on grants and one of two planned major papers is almost ready for submission.
New Jersey's links to the 21st century : maximizing the impact of infrastructure investment
DOT National Transportation Integrated Search
2002-12-01
New Jersey has made significant investments in transportation over the last 10 years, and numerous additional projects are planned or proposed for the next decade and beyond. These investments have improved and will continue to improve accessibility ...
Geometry in Early Years: Sowing Seeds for a Mathematical Definition of Squares and Rectangles
ERIC Educational Resources Information Center
Bartolini Bussi, Maria G.; Baccaglini-Frank, Anna
2015-01-01
In early years schooling it is becoming common to propose activities that involve moving along paths, or programming robots to do so. In order to promote continuity towards the introduction of geometry in primary school, we developed a long-term teaching experiment (with 15 sessions) carried out over 4 months in a first grade classroom in northern…
ERIC Educational Resources Information Center
Boyd, Marcia D.
2014-01-01
Financial aid programs are supposed to improve access and affordability in higher education (Gillen, 2009). The effectiveness of these programs is increasingly being questioned as college attainment figures stagnate and the financial burden on students and families continues to climb year after year. The purpose of this study was to examine the…
DOT National Transportation Integrated Search
2002-04-01
The National Railroad Passenger Corporation (Amtrak) is the nation's intercity passenger rail operator. In recent years, facing the continuing deterioration of its financial condition and its attempt to eliminate its need for federal operating assist...
2013-08-07
This final rule updates the hospice payment rates and the wage index for fiscal year (FY) 2014, and continues the phase out of the wage index budget neutrality adjustment factor (BNAF). Including the FY 2014 15 percent BNAF reduction, the total 5 year cumulative BNAF reduction in FY 2014 will be 70 percent. The BNAF phase-out will continue with successive 15 percent reductions in FY 2015 and FY 2016. This final rule also clarifies how hospices are to report diagnoses on hospice claims, and provides updates to the public on hospice payment reform. Additionally, this final rule changes the requirements for the hospice quality reporting program by discontinuing currently reported measures and implementing a Hospice Item Set with seven National Quality Forum (NFQ) endorsed measures beginning July 1, 2014, as proposed. Finally, this final rule will implement the hospice Experience of Care Survey on January 1, 2015, as proposed.
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. House.
The report on the Nurse Training Act of 1975 focuses on the legislation to provide funds for nursing education through an amendment of title VIII of the Public Health Service Act. It proposes to continue, without change, for fiscal year 1975 the nurse training authorities of title VIII of the Act and to continue the authorities for fiscal years…
NASA Astrophysics Data System (ADS)
Gorjian, Varoujan; Barth, Aaron; Brandt, Niel; Dawson, Kyle; Green, Paul; Ho, Luis; Horne, Keith; Jiang, Linhua; McGreer, Ian; Schneider, Donald; Shen, Yue; Tao, Charling
2018-05-01
Previous Spitzer reverberation monitoring projects searching for UV/optical light absorbed and re-emitted in the IR by dust have been limited to low luminosity active galactic nuclei (AGN) that could potentially show reverberation within a single cycle ( 1 year). Cycle 11-12's two year baseline allowed for the reverberation mapping of 17 high-luminosity quasars from the Sloan Digital Sky Survey Reverberation Mapping project. We continued this monitoring in Cycle 13 and now propose to extend this program in Cycle 14. By combining ground-based monitoring from Pan-STARRS, CFHT, and Steward Observatory telescopes with Spitzer data we have for the first time detected dust reverberation in quasars. By continuing observations with this unqiue combination of resources we should detect reverberation in more objects and reduce the uncertainties for the remaining sources.
A Dynamic Action in the Engineering Teaching.
ERIC Educational Resources Information Center
Pegollo, Carlos Alberto Goebel; Shiga, Alberto Akio
The main proposal of this paper is to present research performed during a practical subject in the last year of the electrical engineer undergraduate course, emphasis in electrotechnics, at the Universidade Sao Judas Tadeu. Several activities are developed to provide the students variable and continued information about their performance in many…
ERIC Educational Resources Information Center
Schultz, Corey
2007-01-01
Tornados damage and destroy schools every year, but many school designers and planners continue to propose new facilities that do not incorporate storm safety techniques. They often subscribe to the "it can't happen here" idea or argue that making schools safe is too expensive. On the heels of two violent storms that damaged schools in…
Adaptive Core Requirements for an Ever Changing Electrical Engineering Curriculum.
ERIC Educational Resources Information Center
Daneshvar, K.; Tranjan, F. M.
Although in the liberal arts the main concern is comprehensive education, it is generally accepted that an engineering curriculum, while providing the fundamentals, can change continuously to accommodate technological, industrial, and economical interests. Meanwhile, in recent years many new forms of learning have been proposed that are quite…
A General Cognitive Diagnosis Model for Continuous-Response Data
ERIC Educational Resources Information Center
Minchen, Nathan; de la Torre, Jimmy
2018-01-01
Cognitive diagnosis models (CDMs) allow for the extraction of fine-grained, multidimensional diagnostic information from appropriately designed tests. In recent years, interest in such models has grown as formative assessment grows in popularity. Many dichotomous as well as several polytomous CDMs have been proposed in the last two decades, but…
The Economic Consequences of Absent Parents. JCPR Working Paper.
ERIC Educational Resources Information Center
Page, Marianne E.; Stevens, Ann Huff
In recent years, the belief that marriage bestows large economic gains has generated enthusiasm for policy proposals that encourage the formation and continuation of two-parent families. This study examined the effects of family structure on economic resources, controlling for unobservable family background characteristics. Data were drawn from…
76 FR 38943 - Notice of Order Soliciting Community Proposals
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-01
... in receiving a grant under the Small Community Air Service Development Program. The full text of the... 2011 Full-Year Continuing Appropriations Act (Pub. L. 112-10 (extending the FY 2010 Consolidated... recipient. Full community participation is a key goal of this program as demonstrated by the statute's focus...
Losing Stuff Down a Black Hole
NASA Astrophysics Data System (ADS)
Okon, Elias; Sudarsky, Daniel
2018-03-01
Over the years, the so-called black hole information loss paradox has generated an amazingly diverse set of (often radical) proposals. However, 40 years after the introduction of Hawking's radiation, there continues to be a debate regarding whether the effect does, in fact, lead to an actual problem. In this paper we try to clarify some aspect of the discussion by describing two possible perspectives regarding the landscape of the information loss issue. Moreover, we advance a fairly conservative point of view regarding the relation between evaporating black holes and the rest of physics, which leads us to advocate a generalized breakdown of unitarity. We conclude by exploring some implications of our proposal in relation with conservation laws.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-25
... Amend the Quantitative Continued Listing Standards Applicable to Companies Listed Under Sections 102.01C... Proposed Rule Change The Exchange proposes to harmonize the quantitative continued listing standards... Proposed Rule Change 1. Purpose The Exchange proposes to harmonize the quantitative continued listing...
Salinas, Maria; López-Garrigós, Maite; Gutiérrez, Mercedes; Lugo, Javier; Sirvent, Jose Vicente; Uris, Joaquin
2010-01-01
Laboratory performance can be measured using a set of model key performance indicators (KPIs). The design and implementation of KPIs are important issues. KPI results from 7 years are reported and their implementation, monitoring, objectives, interventions, result reporting and delivery are analyzed. The KPIs of the entire laboratory process were obtained using Laboratory Information System (LIS) registers. These were collected automatically using a data warehouse application, spreadsheets and external quality program reports. Customer satisfaction was assessed using surveys. Nine model laboratory KPIs were proposed and measured. The results of some examples of KPIs used in our laboratory are reported. Their corrective measurements or the implementation of objectives led to improvement in the associated KPIs results. Measurement of laboratory performance using KPIs and a data warehouse application that continuously collects registers and calculates KPIs confirmed the reliability of indicators, indicator acceptability and usability for users, and continuous process improvement.
75 FR 62403 - Agency Information Collection Activities: Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-08
... Project: 2011-2014 National Survey on Drug Use and Health: Methodological Field Tests (OMB No. 0930-0290..., SAMHSA received a three-year renewal of its generic clearance for methodological field tests. This will be a request for another renewal of the generic approval to continue methodological tests over the...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-02
... the SIPP, which is a household-based survey designed as a continuous series of national panels. New... the panel. The core is supplemented with questions designed to address specific needs, such as... be measured over time. The 2008 panel is currently scheduled for approximately 6 years and will...
ERIC Educational Resources Information Center
Marx, Helen A.; Moss, David M.
2015-01-01
International experiences through structured study abroad programs are proposed as a powerful way to impact pre-service teachers' intercultural understandings and competence. In recent years attention has been placed on the nature of such study abroad programs, seeking to illuminate design elements that might enhance intercultural learning prior…
School Finance 2005?06. Budget Sets Off Public Battle
ERIC Educational Resources Information Center
Perry, Mary
2005-01-01
For the past year, the issue of public education funding has been particularly contentious in California. A pitched political battle between education advocates and the administration of Gov. Arnold Schwarzenegger began with a December 2004 preview of the governor's budget proposal for 2005?06. The fight continued through a spring filled with…
77 FR 61411 - Proposed Data Collections Submitted for Public Comment and Recommendations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-09
... three-year clearance request for the National Hospital Care Survey includes data collection from... Bill (UB-04) administrative claims data as well as facility level data. This activity continues in 2013... sector, foundations, and a variety of users in the print media. Data collected through NHCS are essential...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-09
...)(xiv) would provide that: ``third- party business'' means an engagement by a municipal entity of a... advisory engagements while continuing to receive compensation. Accordingly, the MSRB is proposing to... provides that, in the case of employees who do not solicit investment advisory business, a two-year ``time...
ERIC Educational Resources Information Center
Scott, David A.; Belke, Stephanie L.; Barfield, Hannah G.
2011-01-01
The number of transgender college students continues to increase every year. These students face unique challenges that many college and university career centers are not prepared to handle. This article describes some of the challenges facing transgender students and college career centers. A professional development design is proposed to assist…
The Measurement of Multidimensional Gender Inequality: Continuing the Debate
ERIC Educational Resources Information Center
Permanyer, Inaki
2010-01-01
The measurement of multidimensional gender inequality is an increasingly important topic that has very relevant policy applications and implications but which has not received much attention from the academic literature. In this paper I make a comprehensive and critical review of the indices proposed in recent years in order to systematise the…
Careers Boundaries in the Arts in Brazil: An Exploratory Study
ERIC Educational Resources Information Center
Bendassolli, Pedro F.; Wood, Thomaz, Jr.
2012-01-01
Over the last years the scholarly literature on careers has been enriched by the proposal of new career models which present a rhetoric that asks for the end of career boundaries: individual, hierarchical, organizational and geographical. However, in the real world, many constrains continue to exist. This paper tries to contribute to the…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-25
... ratio requirement consistent with or similar to those in the Basel III accords. The Commission also... of customer funds that the Commission continually has promoted over the years. III. Consideration of... registered as such with the Commission; or (iii) A derivatives clearing organization. * * * * * PART 4...
78 FR 14879 - Revision of Fee Schedules; Fee Recovery for Fiscal Year 2013
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-07
...The U.S. Nuclear Regulatory Commission (NRC) is proposing to amend the licensing, inspection, and annual fees charged to its applicants and licensees. The proposed amendments are necessary to implement the Omnibus Budget Reconciliation Act of 1990 (OBRA-90), as amended, which requires the NRC to recover through fees approximately 90 percent of its budget authority in Fiscal Year (FY) 2013, not including amounts appropriated for Waste Incidental to Reprocessing (WIR) and amounts appropriated for generic homeland security activities. The NRC is currently operating under a Continuing Resolution (CR) which is set to expire on March 27, 2013. Based on the FY 2013 budget submitted to the Congress, the NRC is proposing fees in this rulemaking based on the FY 2013 budget which is estimated to be $1,053.2 million. After accounting for billing adjustments, the total amount to be billed as fees is approximately $924.8 million. These fees are subject to change pending congressional action which may include sequestration, full-year CR or issuance of an FY 2013 appropriation which differs from the FY 2013 budget submitted to Congress which could result in higher or lower fees than those proposed in this rulemaking.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-18
...This proposed rule would revise the Medicare hospital outpatient prospective payment system (OPPS) to implement applicable statutory requirements and changes arising from our continuing experience with this system. In this proposed rule, we describe the proposed changes to the amounts and factors used to determine the payment rates for Medicare hospital outpatient services paid under the OPPS. These proposed changes would be applicable to services furnished on or after January 1, 2012. In addition, this proposed rule would update the revised Medicare ambulatory surgical center (ASC) payment system to implement applicable statutory requirements and changes arising from our continuing experience with this system. In this proposed rule, we set forth the proposed relative payment weights and payment amounts for services furnished in ASCs, specific HCPCS codes to which these proposed changes would apply, and other proposed ratesetting information for the CY 2012 ASC payment system. These proposed changes would be applicable to services furnished on or after January 1, 2012. We are proposing to revise the requirements for the Hospital Outpatient Quality Reporting (IQR) Program, add new requirements for ASC Quality Reporting System, and make additional changes to provisions of the Hospital Inpatient Value-Based Purchasing (VBP) Program. We also are proposing to allow eligible hospitals and CAHs participating in the Medicare Electronic Health Record (EHR) Incentive Program to meet the clinical quality measure reporting requirement of the EHR Incentive Program for payment year 2012 by participating in the 2012 Medicare EHR Incentive Program Electronic Reporting Pilot. In addition, we are proposing to make changes to the rules governing the whole hospital and rural provider exceptions to the physician self-referral prohibition for expansion of facility capacity and changes to provider agreement regulations on patient notification requirements.
Proposed Budget for U.S. Geological Survey: A Mixed Bag of Increases and Cuts
NASA Astrophysics Data System (ADS)
Showstack, Randy
2011-03-01
Under the Obama administration's proposed fiscal year (FY) 2012 budget, the U.S. Geological Survey (USGS) would receive $1.1 billion, a scant $6.1 million more than the 2010 enacted budget. Within the agency, which is part of the Department of the Interior (DOI), some key initiatives slated for new or increased funding include the National Land Imaging Program, the USGS portion of the America's Great Outdoors Initiative, and DOI Climate Science Centers. However, the request also includes $89.1 million in program reductions and the elimination of some programs. With Congress currently considering a budget continuing resolution to fund the federal government through the end of the current fiscal year, 2011, USGS faces possible additional cuts.
Wang, Yanqin; Pu, Mingbo; Zhang, Zuojun; Li, Xiong; Ma, Xiaoliang; Zhao, Zeyu; Luo, Xiangang
2015-12-04
Two-dimensional metasurface has attracted growing interest in recent years, owing to its ability in manipulating the phase, amplitude and polarization state of electromagnetic wave within a single interface. However, most existing metasurfaces rely on the collective responses of a set of discrete meta-atoms to perform various functionalities. In this paper, we presented a quasi-continuous metasurface for high-efficiency and broadband beam steering in the microwave regime. It is demonstrated both in simulation and experiment that the incident beam deviates from the normal direction after transmitting through the ultrathin metasurface. The efficiency of the proposed metasurface approximates to the theoretical limit of the single-layer metasurface in a broad frequency range, owing to the elimination of the circuit resonance in traditional discrete structures. The proposed scheme promises potential applications in broadband electromagnetic modulation and communication systems, etc.
Pediatric Glioblastoma Therapies Based on Patient-Derived Stem Cell Resources
2013-10-01
stem cell lines have been successfully isolated from adults, in this proposal we aim to isolate and characterize GSC populations from pediatric patients. In the past two years we have successfully derived and cultured eight patient-derived pediatric glioma stem cell lines. In the past year we have continued molecular and phenotypic characterization of these lines. This characterization included analysis of gene expression and patient-specific gene mutations, and also proof-of-concept shRNA screens. In addition we have begun to identify candidate
A new experimental proposal for {sup 235}U PFNS to answer a fifty years old question
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kornilov, N.; Massey, T.; Grimes, S.
2011-07-01
The Prompt Fission Neutron Spectrum (PFNS) from {sup 235}U(n,f) is very important for various nuclear applications. It has been investigated in different experiments. In spite of {approx}50 years of experimental efforts, a continuing conflict exists at thermal neutron energy. Microscopic experimental PFNS cannot describe macroscopic data. In this report we discuss the current status of this problem and suggest a new experiment, which could possibly resolve this problem. (authors)
1988-01-01
i.e., programs gen - erally subject to control by annual appropriations) were $6.3 billion above the Administration’s original request for policy reasons...unobligated balance avail- Amounts for proposed new legislation are shown gen - able, end of year. That balance is carried forward and erally in separate...Program and Financing (in thousands of dollars) Trident strategic missile and submarine continues. Gen - lan 97-0819-0-1-051 199 actual 1909 e. 19eral
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-26
... by high equipment and operating costs, continued safety concerns and other logistical constraints... impact on a substantial number of small entities. The analysis follows: The proposed rule would extend... initial regulatory flexibility analysis is not required and none has been prepared. List of Subjects in 50...
Effective Continuing Education for Licensed Real Estate Professionals
ERIC Educational Resources Information Center
Tilton, Wendy A.
2004-01-01
Mandatory real estate education has been intensely debated for many years. New Jersey is the only state in the nation that does not require licensed real estate agents to attend an ongoing educational event after securing a license to practice. A bill was proposed to the legislature to mandate real estate education in June of 2001. (It was…
Financial Forces and the Future of American Higher Education
ERIC Educational Resources Information Center
Ehrenberg, Ronald G.; Rizzo, Michael J.
2004-01-01
Each year over the past quarter century, undergraduate tuition and fees in the United States have increased by an average of 2.5 to 3.5 percentage points above the inflation rate. This continuous rise recently led one congressman to propose that the government penalize institutions that raise their tuition by more than twice the rate of inflation…
ERIC Educational Resources Information Center
Kimball, Bruce A.
2014-01-01
This article examines the prominent narrative asserting that liberal arts colleges have continuously declined in number and status over the past 130 years. Bruce A. Kimball identifies problems in this declension narrative and proposes a revision positing that the decline of liberal arts colleges began only after 1970. Further, he maintains that…
Bioregenerative Life-Support System For Long Missions
NASA Technical Reports Server (NTRS)
Cullingford, Hatice S.
1994-01-01
Collection of four reports proposes integrated bioregenerative life-support system that sustains tens of people isolated from Earth's oxygen and sunlight. System self-sufficient for year or more; continues beyond that period with replenishment of supplies. Used in long-term spaceflights, space stations, such planet bases as those on Earth's Moon or Mars, and submarine vehicles and installations.
The Philosophy and Structure of the Curriculum in University Technical Colleges
ERIC Educational Resources Information Center
Tomlinson, Mike
2014-01-01
Arguments about the content and structure of the curriculum for 14- to 18-year-old students in England continue apace, not least as a consequence of the National Curriculum review and proposed changes to qualifications. However, the majority of initiatives aimed at providing high-quality and rigorous technical pathways from age 14 onwards have…
Science Receives Broad Support in Obama Administration's Proposed Budget
NASA Astrophysics Data System (ADS)
Showstack, Randy
2011-02-01
With the U.S. federal deficit on target to hit $1.5 trillion this year, President Barack Obama's proposed federal budget of $3.73 trillion for fiscal year (FY) 2012, which begins on 1 October, has been greeted with mixed reviews since its release on 14 February. The proposal, which calls for a 5-year overall freeze on discretionary spending outside of security, generally is favorable for science and science agencies—particularly the National Science Foundation (NSF), the Department of Energy's (DOE) Office of Science, and the National Institute of Standards and Technology's (NIST) laboratories. However, some other agencies and bureaus, including the U.S. Geological Survey (USGS) and the Environmental Protection Agency (EPA), do not fare as well. A number of Republicans in Congress have panned the budget. Rep. Paul Ryan (R-Wis.), chair of the House of Representatives Committee on the Budget, said the president “has failed to tackle the urgent fiscal and economic threats before us.” Also, with the FY 2011 budget never having been enacted, House Committee on Appropriations chair Hal Rogers (R-Ky.) introduced a continuing resolution (H.R. 1) on 11 February that would fund the federal government for the remainder of the current fiscal year at a level $100 billion below the administration's request for this year.
Future Mission Proposal Opportunities: Discovery, New Frontiers, and Project Prometheus
NASA Technical Reports Server (NTRS)
Niebur, S. M.; Morgan, T. H.; Niebur, C. S.
2003-01-01
The NASA Office of Space Science is expanding opportunities to propose missions to comets, asteroids, and other solar system targets. The Discovery Program continues to be popular, with two sample return missions, Stardust and Genesis, currently in operation. The New Frontiers Program, a new proposal opportunity modeled on the successful Discovery Program, begins this year with the release of its first Announcement of Opportunity. Project Prometheus, a program to develop nuclear electric power and propulsion technology intended to enable a new class of high-power, high-capability investigations, is a third opportunity to propose solar system exploration. All three classes of mission include a commitment to provide data to the Planetary Data System, any samples to the NASA Curatorial Facility at Johnson Space Center, and programs for education and public outreach.
Louisiana NASA EPSCoR Preparation Grant
NASA Technical Reports Server (NTRS)
Wefel, John P.; Savoie, E. Joseph
2002-01-01
In August, 1999, the National Aeronautics and Space Administration issued a Cooperative Agreement (CA) to the State of Louisiana, through the Louisiana Board of Regents (BOB), for the performance of scientific research and graduate fellowships under the NASA Experimental Program to Stimulate Competitive Research (EPSCoR) -- Preparation Grant. Originally constructed as a one year program, with an optional one year continuation, this federal-state partnership culminated on 14 August 2002, including a successful continuation proposal and a no cost extension. The total value of the project reached $450K in NASA funding, matched by state funds and institutional contributions. The purpose of the Preparation Grant program was to develop and nurture strong research ties between the state and NASA field centers and Enterprises, in order to prepare for the upcoming full competition for NASA EPSCoR.
Ancient European dog genomes reveal continuity since the Early Neolithic
Botigué, Laura R.; Song, Shiya; Scheu, Amelie; Gopalan, Shyamalika; Pendleton, Amanda L.; Oetjens, Matthew; Taravella, Angela M.; Seregély, Timo; Zeeb-Lanz, Andrea; Arbogast, Rose-Marie; Bobo, Dean; Daly, Kevin; Unterländer, Martina; Burger, Joachim; Kidd, Jeffrey M.; Veeramah, Krishna R.
2017-01-01
Europe has played a major role in dog evolution, harbouring the oldest uncontested Palaeolithic remains and having been the centre of modern dog breed creation. Here we sequence the genomes of an Early and End Neolithic dog from Germany, including a sample associated with an early European farming community. Both dogs demonstrate continuity with each other and predominantly share ancestry with modern European dogs, contradicting a previously suggested Late Neolithic population replacement. We find no genetic evidence to support the recent hypothesis proposing dual origins of dog domestication. By calibrating the mutation rate using our oldest dog, we narrow the timing of dog domestication to 20,000–40,000 years ago. Interestingly, we do not observe the extreme copy number expansion of the AMY2B gene characteristic of modern dogs that has previously been proposed as an adaptation to a starch-rich diet driven by the widespread adoption of agriculture in the Neolithic. PMID:28719574
New readout integrated circuit using continuous time fixed pattern noise correction
NASA Astrophysics Data System (ADS)
Dupont, Bertrand; Chammings, G.; Rapellin, G.; Mandier, C.; Tchagaspanian, M.; Dupont, Benoit; Peizerat, A.; Yon, J. J.
2008-04-01
LETI has been involved in IRFPA development since 1978; the design department (LETI/DCIS) has focused its work on new ROIC architecture since many years. The trend is to integrate advanced functions into the CMOS design to achieve cost efficient sensors production. Thermal imaging market is today more and more demanding of systems with instant ON capability and low power consumption. The purpose of this paper is to present the latest developments of fixed pattern noise continuous time correction. Several architectures are proposed, some are based on hardwired digital processing and some are purely analog. Both are using scene based algorithms. Moreover a new method is proposed for simultaneous correction of pixel offsets and sensitivities. In this scope, a new architecture of readout integrated circuit has been implemented; this architecture is developed with 0.18μm CMOS technology. The specification and the application of the ROIC are discussed in details.
Exponential Family Functional data analysis via a low-rank model.
Li, Gen; Huang, Jianhua Z; Shen, Haipeng
2018-05-08
In many applications, non-Gaussian data such as binary or count are observed over a continuous domain and there exists a smooth underlying structure for describing such data. We develop a new functional data method to deal with this kind of data when the data are regularly spaced on the continuous domain. Our method, referred to as Exponential Family Functional Principal Component Analysis (EFPCA), assumes the data are generated from an exponential family distribution, and the matrix of the canonical parameters has a low-rank structure. The proposed method flexibly accommodates not only the standard one-way functional data, but also two-way (or bivariate) functional data. In addition, we introduce a new cross validation method for estimating the latent rank of a generalized data matrix. We demonstrate the efficacy of the proposed methods using a comprehensive simulation study. The proposed method is also applied to a real application of the UK mortality study, where data are binomially distributed and two-way functional across age groups and calendar years. The results offer novel insights into the underlying mortality pattern. © 2018, The International Biometric Society.
Proposal Improvements That Work
NASA Technical Reports Server (NTRS)
Dunn, F.
1998-01-01
Rocketdyne Propulsion and Power, an operating location of Boeing in Canoga Park, California is under contract with NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama for design, development, production, and mission support of Space Shuttle Main Engines (SSMEs). The contract was restructured in 1996 to emphasize a mission contracting environment under which Rocketdyne supports the Space Transportation System launch manifest of seven flights a year without the need for a detailed list of contract deliverables such as nozzles, turbopumps, and combustion devices. This contract structure is in line with the overall Space Shuttle program goals established by the NASA to fly safely, meet the flight manifest, and reduce cost. Rocketdyne's Contracts, Pricing, and Estimating team has worked for the past several years with representatives from MSFC, the local Defense Contract Management Command, and the DCAA to improve the quality of cost proposals to MSFC for contract changes on the SSME. The contract changes on the program result primarily from engineering change proposals for product enhancements to improve safety, maintainability, or operability in the space environment. This continuous improvement team effort has been successful in improving proposal quality, reducing cycle time, and reducing cost. Some of the principal lessons learned are highlighted here to show how proposal improvements can be implemented to enhance customer satisfaction and ensure cost proposals can be evaluated easily by external customers.
Information system end-user satisfaction and continuance intention: A unified modeling approach.
Hadji, Brahim; Degoulet, Patrice
2016-06-01
Permanent evaluation of end-user satisfaction and continuance intention is a critical issue at each phase of a clinical information system (CIS) project, but most validation studies are concerned with the pre- or early post-adoption phases. The purpose of this study was twofold: to validate at the Pompidou University Hospital (HEGP) an information technology late post-adoption model built from four validated models and to propose a unified metamodel of evaluation that could be adapted to each context or deployment phase of a CIS project. Five dimensions, i.e., CIS quality (CISQ), perceived usefulness (PU), confirmation of expectations (CE), user satisfaction (SAT), and continuance intention (CI) were selected to constitute the CI evaluation model. The validity of the model was tested using the combined answers to four surveys performed between 2011 and 2015, i.e., more than ten years after the opening of HEGP in July 2000. Structural equation modeling was used to test the eight model-associated hypotheses. The multi-professional study group of 571 responders consisted of 158 doctors, 282 nurses, and 131 secretaries. The evaluation model accounted for 84% of variance of satisfaction and 53% of CI variance for the period 2011-2015 and for 92% and 69% for the period 2014-2015. In very late post adoption, CISQ appears to be the major determinant of satisfaction and CI. Combining the results obtained at various phases of CIS deployment, a Unified Model of Information System Continuance (UMISC) is proposed. In a meaningful CIS use situation at HEGP, this study confirms the importance of CISQ in explaining satisfaction and CI. The proposed UMISC model that can be adapted to each phase of CIS deployment could facilitate the necessary efforts of permanent CIS acceptance and continuance evaluation. Copyright © 2016 Elsevier Inc. All rights reserved.
Continuous event monitoring via a Bayesian predictive approach.
Di, Jianing; Wang, Daniel; Brashear, H Robert; Dragalin, Vladimir; Krams, Michael
2016-01-01
In clinical trials, continuous monitoring of event incidence rate plays a critical role in making timely decisions affecting trial outcome. For example, continuous monitoring of adverse events protects the safety of trial participants, while continuous monitoring of efficacy events helps identify early signals of efficacy or futility. Because the endpoint of interest is often the event incidence associated with a given length of treatment duration (e.g., incidence proportion of an adverse event with 2 years of dosing), assessing the event proportion before reaching the intended treatment duration becomes challenging, especially when the event onset profile evolves over time with accumulated exposure. In particular, in the earlier part of the study, ignoring censored subjects may result in significant bias in estimating the cumulative event incidence rate. Such a problem is addressed using a predictive approach in the Bayesian framework. In the proposed approach, experts' prior knowledge about both the frequency and timing of the event occurrence is combined with observed data. More specifically, during any interim look, each event-free subject will be counted with a probability that is derived using prior knowledge. The proposed approach is particularly useful in early stage studies for signal detection based on limited information. But it can also be used as a tool for safety monitoring (e.g., data monitoring committee) during later stage trials. Application of the approach is illustrated using a case study where the incidence rate of an adverse event is continuously monitored during an Alzheimer's disease clinical trial. The performance of the proposed approach is also assessed and compared with other Bayesian and frequentist methods via simulation. Copyright © 2015 John Wiley & Sons, Ltd.
Mental Illness and/or Mental Health? Investigating Axioms of the Complete State Model of Health
ERIC Educational Resources Information Center
Keyes, Corey L. M.
2005-01-01
A continuous assessment and a categorical diagnosis of the presence (i.e., flourishing) and the absence (i.e., languishing) of mental health were proposed and applied to the Midlife in the United States study data, a nationally representative sample of adults between the ages of 25 and 74 years (N = 3,032). Confirmatory factor analyses supported…
Memory--a century of consolidation.
McGaugh, J L
2000-01-14
The memory consolidation hypothesis proposed 100 years ago by Müller and Pilzecker continues to guide memory research. The hypothesis that new memories consolidate slowly over time has stimulated studies revealing the hormonal and neural influences regulating memory consolidation, as well as molecular and cellular mechanisms. This review examines the progress made over the century in understanding the time-dependent processes that create our lasting memories.
Donald L. Rockwood; Bijay Tamang; Matias Kirst; JY Zhu
2012-01-01
For several methods utilizing woody biomass for energy (Rockwood and others 2008), one of the challenges is the large, continuous fuel supply required. For example, proposed biomass plants in Florida may each require one million tons of biomass/year. When supplies of forest residues and urban wood wastes are limited, short rotation woody crops (SRWC) are a viable...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-26
... expansion of the survey to better reflect the current state of academic R&D. The redesigned survey was renamed the Higher Education R&D Survey and was pilot tested with a random sample of 40 institutions... proposed project will continue the annual survey cycle for three years. The FY 2010 Higher Education R&D...
1989-01-01
extensive system for cataloging books and periodical literature on Africa from all worldwide sources, forms a tribute to the years of fruitful effort...symbolic recognition that the growing African elite had valid opinions that should be taken into consider- ation in the making of decisions affecting ...constitutional proposals affecting colonial issues. From this point on, this con- servative group representing Franco-African business interests would continue to
Adverse consequences of lysergic acid diethylamide.
Abraham, H D; Aldridge, A M
1993-10-01
The continued endemic use of hallucinogenic drugs, and of LSD in particular, raises concern regarding their short and long term adverse consequences. The epidemiology of LSD abuse is reviewed suggesting an increase in LSD use among the young as the prevalence rates for other substances continues to fall. Evidence supports the association of LSD use with panic reactions, prolonged schizoaffective psychoses and post-hallucinogen perceptual disorder, the latter being present continually for as long as 5 years. Evidence does not support claims of genetic disorders arising from hallucinogens. In light of the foregoing, current data confirm earlier findings of long lasting psychopathology arising in vulnerable individuals from the use of LSD. A hypothetical long term molecular mechanism of adverse effects is proposed.
Multidimensional Conservation Laws and Low Regularity Solutions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barbara Lee Keyfitz
This is the concluding report for the project, a continuation of research by Keyfitz and co-workers on multidimensional conservation laws, and applications of nonhyperbolic conservation laws in the two-fluid model for multiphase flow. The multidimensional research project was started with Suncica Canic, at the University of Houston and with Eun Heui Kim, now at California State University Long Beach. Two postdoctoral researchers, Katarina Jegdic and Allen Tesdall, also worked on this research. Jegdic's research was supported (for a total of one year) by this grant. Work on nonhyperbolic models for two-phase flows is being pursued jointly with Michael Sever, Hebrewmore » University. Background for the project is contained in earlier reports. Note that in 2006, the project received a one-year no-cost extension that will end in September, 2007. A new proposal, for continuation of the research and for new projects, will be submitted in the Fall of 2007, with funding requested to begin in the summer of 2008. The reason for the 'funding gap' is Keyfitz's four-year stint as Director of the Fields Institute in Toronto, Canada. The research has continued, but has been supported by Canadian grant funds, as seems appropriate during this period.« less
Adolescents Exiting Homelessness Over Two Years: The Risk Amplification and Abatement Model
Milburn, Norweeta G.; Rice, Eric; Rotheram-Borus, Mary Jane; Mallett, Shelley; Rosenthal, Doreen; Batterham, Phillip; May, Susanne J.; Witkin, Andrea; Duan, Naihua
2014-01-01
The Risk Amplification and Abatement Model (RAAM), demonstrates that negative contact with socializing agents amplify risk, while positive contact abates risk for homeless adolescents. To test this model, the likelihood of exiting homelessness and returning to familial housing at 2 years and stably exiting over time are examined with longitudinal data collected from 183 newly homeless adolescents followed over 2 years in Los Angeles, CA. In support of RAAM, unadjusted odds of exiting at 2 years and stably exiting over2 years revealed that engagement with pro-social peers, maternal social support, and continued school attendance all promoted exiting behaviors. Simultaneously, exposure to family violence and reliance on shelter services discouraged stably exiting behaviors. Implications for family-based interventions are proposed. PMID:25067896
Water management in Egypt for facing the future challenges
Omar, Mohie El Din M.; Moussa, Ahmed M.A.
2016-01-01
The current water shortage in Egypt is 13.5 Billion cubic meter per year (BCM/yr) and is expected to continuously increase. Currently, this water shortage is compensated by drainage reuse which consequently deteriorates the water quality. Therefore, this research was commenced with the objective of assessing different scenarios for 2025 using the Water Evaluation and Planning (WEAP) model and by implementing different water sufficiency measures. Field data were assembled and analyzed, and different planning alternatives were proposed and tested in order to design three future scenarios. The findings indicated that water shortage in 2025 would be 26 BCM/yr in case of continuation of current policies. Planning alternatives were proposed to the irrigation canals, land irrigation timing, aquatic weeds in waterways and sugarcane areas in old agricultural lands. Other measures were suggested to pumping rates of deep groundwater, sprinkler and drip irrigation systems in new agricultural lands. Further measures were also suggested to automatic daily surveying for distribution leak and managing the pressure effectively in the domestic and industrial water distribution systems. Finally, extra measures for water supply were proposed including raising the permitted withdrawal limit from deep groundwater and the Nubian aquifer and developing the desalination resource. The proposed planning alternatives would completely eliminate the water shortage in 2025. PMID:27222745
Water management in Egypt for facing the future challenges.
Omar, Mohie El Din M; Moussa, Ahmed M A
2016-05-01
The current water shortage in Egypt is 13.5 Billion cubic meter per year (BCM/yr) and is expected to continuously increase. Currently, this water shortage is compensated by drainage reuse which consequently deteriorates the water quality. Therefore, this research was commenced with the objective of assessing different scenarios for 2025 using the Water Evaluation and Planning (WEAP) model and by implementing different water sufficiency measures. Field data were assembled and analyzed, and different planning alternatives were proposed and tested in order to design three future scenarios. The findings indicated that water shortage in 2025 would be 26 BCM/yr in case of continuation of current policies. Planning alternatives were proposed to the irrigation canals, land irrigation timing, aquatic weeds in waterways and sugarcane areas in old agricultural lands. Other measures were suggested to pumping rates of deep groundwater, sprinkler and drip irrigation systems in new agricultural lands. Further measures were also suggested to automatic daily surveying for distribution leak and managing the pressure effectively in the domestic and industrial water distribution systems. Finally, extra measures for water supply were proposed including raising the permitted withdrawal limit from deep groundwater and the Nubian aquifer and developing the desalination resource. The proposed planning alternatives would completely eliminate the water shortage in 2025.
1987-02-19
hours , to move away from things nuclear, to reject the SDI and missiles, to establish a dialogue with Eastern Europe, a new ...meeting of the leadership, Antonio Bassolino announced that the PCI was proposing a reduction of the workweek to 35 hours (until then it had been...budgetary work to become the prelude to a new 4 -year period for the Four-Leaf-Clover government and a continuation and expansion of the
Annual Report (1994) and Five-Year (1994-1998) Strategic Investment Plan.
1994-09-01
include identification of dissolved and solid-associated organic carbon compounds associated with sorption and biodegradative processes. The participation...exploiting the low surface energy of surface oriented perfluorinated alkyl compounds . This project is a continuation of the FY93 funded "innovative Very Low...adsorbed monolayers of closely packed perfluorinated compounds . Since adsorbed monolayers are not practical as hull coatings, we propose to simulate
Karhunen-Loeve Analysis of SCIGN GPS Data
NASA Technical Reports Server (NTRS)
Rundle, John B.; Tiampo, Kristy; Gross, Susanna
2004-01-01
During the final year of this project, we made substantial progress on the proposed work. Specifically, we have continued the horizontal and vertical Karhunen-Loeve (KL) analysis of SCIGN data and implemented the study of a number of particular modes. In particular, we studied the spatial and temporal interactions of these modes in an effort to better understand and model the source of each signal.
ERIC Educational Resources Information Center
Llopart, Mariona; Esteban-Guitart, Moisès
2018-01-01
Although the first educational applications of the "funds of knowledge" (FoK) concept were carried out in the late 1980s, there have been numerous developments and proposals since then, many of which have been made within the last few years. It continues to be, therefore, a valid, cutting-edge educational approach; one which seeks to…
ERIC Educational Resources Information Center
Marti, Enric; Gil, Debora; Gurguí, Antoni; Hernández-Sabaté, Aura; Rocarías, Jaume; Poveda, Ferran
2015-01-01
This report presents the organisation of PBL (Project Based Learning) for a subject included in the IT engineering degree course. It is the result of 10 years of experience of the implantation and continuous improvement of the PBL class structure. The latest innovations include the experience of part-time monitoring with PBL groups using the Open…
Astronomy Applications of Adaptive Optics at Lawrence Livermore National Laboratory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bauman, B J; Gavel, D T
2003-04-23
Astronomical applications of adaptive optics at Lawrence Livermore National Laboratory (LLNL) has a history that extends from 1984. The program started with the Lick Observatory Adaptive Optics system and has progressed through the years to lever-larger telescopes: Keck, and now the proposed CELT (California Extremely Large Telescope) 30m telescope. LLNL AO continues to be at the forefront of AO development and science.
Leveraging community support for Education and Outreach: The IRIS E&O Program
NASA Astrophysics Data System (ADS)
Taber, J.; Hubenthal, M.; Wysession, M. E.
2009-12-01
The IRIS E&O Program was initiated 10 years ago, some 15 years after the creation of the IRIS Consortium, as IRIS members increasingly recognized the fundamental need to communicate the results of scientific research more effectively and to attract more students to study Earth science. Since then, IRIS E&O has received core funding through successive 5-year cooperative agreements with NSF, based on proposals submitted by IRIS. While a small fraction of the overall Consortium budget, this consistent funding has allowed the development of strong, long-term elements within the E&O Program, including summer internships, IRIS/USGS museum displays, seismographs in schools, IRIS/SSA Distinguished Lecture series, and professional development for middle school and high school teachers. Reliable funding has allowed us to develop expertise in these areas due to the longevity of the programs and the continuous improvement resulting from ongoing evaluations. Support from Consortium members, including volunteering time and expertise, has been critical for the program, as the Consortium has to continually balance the value of E&O products versus equipment and data services for seismology research. The E&O program also provides service to the Consortium, such as PIs being able to count on and leverage IRIS resources when defining the broader impacts of their own research. The reliable base has made it possible to build on the core elements with focused and innovative proposals, allowing, for example, the expansion of our internship program into a full REU site. Developing collaborative proposals with other groups has been a key strategy where IRIS E&O's long-term viability can be combined with expertise from other organizations to develop new products and services. IRIS can offer to continue to reliably deliver and maintain products after the end of a 2-3 year funding cycle, which can greatly increase the reach of the project. Consortium backing has also allowed us to establish an educational fund in honor of the late John Lahr. This fund, which is comprised of individual donations, is being used to provide seismographs to schools along with professional development and ongoing support from the E&O program. We are also developing a plan for attracting larger private and/or foundation funds for new E&O activities, leveraging the reputation of a long-term program.
Using a Retreat to Develop a 4-Year Sexual Orientation and Gender Identity Curriculum.
Ton, Hendry; Eidson-Ton, W Suzanne; Iosif, Ana-Maria; Sitkin, Nicole; Henderson, Shelly; Callahan, Edward J
2016-10-01
Lesbian, gay, bisexual, and transgender (LGBT) populations experience significant health disparities, yet medical schools report devoting little educational time to the care of this population. In light of this, one School of Medicine utilized a daylong retreat to design a 4-year sexual orientation and gender identity (SOGI) curriculum. The participants completed pre-and post-surveys on their perspectives and knowledge towards SOGI learning, and the school's curriculum database was reviewed 2 years later to ascertain the degree of implementation of the proposed curriculum. Significant improvements were observed in participants' confidence in creating an SOGI curriculum, knowledge of SOGI teaching resources, and where in the curriculum SOGI competencies are and should be taught. A 6-month follow-up survey yielded a lower response rate, but suggested strong ongoing support for the new curriculum and some continuing challenges to implementing the proposed curriculum. A review of the school's curriculum database 2 years later showed an implementation rate of 76 %. A focused and systematic retreat can be an effective tool for curriculum design and implementation.
Emerging and continuing trends in psychotherapy: views from an editor's eye.
Gelso, Charles J
2011-06-01
It is proposed that six major trends in psychotherapy have continued or emerged over the course of the author's editorship of Psychotherapy, the past seven years. These trends are (a) the increasing integration of techniques and the therapeutic relationship; (b) increasing focus on theoretical integration; (c) increasing efforts at research-practice integration; (d) increases in more specific, integrative reviews; (e) integration of biological, neuroscience understandings; and (f) integration of diversity and cultural considerations into psychotherapy. Each trend is described and its impact on the field is discussed. Cautions about each trend are also noted. The six trends are discussed in the context of integration.
Ribas, F; Frias, J; Lucena, F
1991-10-01
A new method for the determination of biodegradable dissolved organic carbon (BDOC), which may be useful to the water industry, is proposed. It is a dynamic method that measures the BDOC of circulating water continuously pumped across a biofilm attached to a special support that fills a system of two glass columns. The BDOC value corresponds to the difference in DOC between inlet and outlet water samples. The sampling may be intermittent or continuous, but the process is continuous. The biofilms give good performances over periods of at least 1 year. The analytical results are not significantly different from those of other bioassays based on the use of indigenous bacteria and the total duration of analysis is between 2 and 3 h.
76 FR 63238 - Proximity Detection Systems for Continuous Mining Machines in Underground Coal Mines
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-12
... Detection Systems for Continuous Mining Machines in Underground Coal Mines AGENCY: Mine Safety and Health... Agency's proposed rule addressing Proximity Detection Systems for Continuous Mining Machines in... proposed rule for Proximity Detection Systems on Continuous Mining Machines in Underground Coal Mines. Due...
76 FR 677 - Requirements for Importers of Nonhuman Primates
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-05
...CDC is proposing to amend its regulations for the importation of live nonhuman primates (NHPs) by extending existing requirements for the importation of Macaca fascicularis (cynomolgus), Chlorocebus aethiops (African green), and Macaca mulatta (rhesus) monkeys to all NHPs. Filovirus testing will continue to be required only for Old World NHPs. CDC also is proposing to reduce the frequency at which importers of cynomolgus, African green, and rhesus monkeys are required to renew their registrations, (from every 180 days to every two years). CDC proposes to incorporate existing guidelines into the regulations and add new provisions to address: NHPs imported as part of a trained animal act; NHPs imported or transferred by zoological societies; The transfer of NHPs from approved laboratories; and Non-live imported NHP products. CDC is also proposing that all NHPs be imported only through ports of entry where a CDC quarantine station is located.
Space-ecology set covering problem for modeling Daiyun Mountain Reserve, China
NASA Astrophysics Data System (ADS)
Lin, Chih-Wei; Liu, Jinfu; Huang, Jiahang; Zhang, Huiguang; Lan, Siren; Hong, Wei; Li, Wenzhou
2018-02-01
Site selection is an important issue in designing the nature reserve that has been studied over the years. However, a well-balanced relationship between preservation of biodiversity and site selection is still challenging. Unlike the existing methods, we consider three critical components, the spatial continuity, spatial compactness and ecological information to address the problem of designing the reserve. In this paper, we propose a new mathematical model of set covering problem called Space-ecology Set Covering Problem (SeSCP) for designing a reserve network. First, we generate the ecological information by forest resource investigation. Then, we split the landscape into elementary cells and calculate the ecological score of each cell. Next, we associate the ecological information with the spatial properties to select a set of cells to form a nature reserve for improving the ability of protecting the biodiversity. Two spatial constraints, continuity and compactability, are given in SeSCP. The continuity is to ensure that any selected site has to be connected with adjacent sites and the compactability is to minimize the perimeter of the selected sites. In computational experiments, we take Daiyun Mountain as a study area to demonstrate the feasibility and effectiveness of the proposed model.
Earth and space science funding at risk
NASA Astrophysics Data System (ADS)
Buhrman, Joan
2011-07-01
With debt ceiling deadlines quickly approaching, U.S. lawmakers are still markedly divided over how to address the nation's economic and budgetary troubles. AGU is closely monitoring these debates and any cuts directed at funding for scientific research and development. Cuts beyond the already reduced levels from the current fiscal year 2011 continuing resolution have the potential to be devastating not only for the scientific community but also for the health, safety, and welfare of the public and America's economic competitiveness. It is not clear how the current proposals would apply to cutting scientific research and development, but it is very likely that federal funding levels for fiscal year 2012 will be even lower than those seen in 2011, a trend that could continue for a number of years. The Obama administration and congressional leadership are reported to be negotiating up to $4 trillion in reduced expenditures, with cuts of at least $1.1 trillion being made in discretionary appropriations over the next 10 years, starting in fiscal year 2012. While it is possible that a smaller, interim deal could pass, which would bring another debt ceiling vote before November 2012, there is significant opposition to such a stopgap measure.
Efficiency optimization of wireless power transmission systems for active capsule endoscopes.
Zhiwei, Jia; Guozheng, Yan; Jiangpingping; Zhiwu, Wang; Hua, Liu
2011-10-01
Multipurpose active capsule endoscopes have drawn considerable attention in recent years, but these devices continue to suffer from energy limitations. A wireless power supply system is regarded as a practical way to overcome the power shortage problem in such devices. This paper focuses on the efficiency optimization of a wireless energy supply system with size and safety constraints. A mathematical programming model in which these constraints are considered is proposed for transmission efficiency, optimal frequency and current, and overall system effectiveness. To verify the feasibility of the proposed method, we use a wireless active capsule endoscope as an illustrative example. The achieved efficiency can be regarded as an index for evaluating the system, and the proposed approach can be used to direct the design of transmitting and receiving coils.
Fabrication of 1-dimension nano-material-based device and its electrical characteristics
NASA Astrophysics Data System (ADS)
Yang, Xing; Zhou, Zhaoying; Zheng, Fuzhong; Zhang, Min
2008-12-01
In recent years, many kinds of 1-dimension nano-materials (Carbon nanotube, ZnO nanobelt and nanowire etc.) continue to emerge which exhibit distinct and unique electromechanical, piezoelectric, photoelectrical properties. In this paper, a 1-dimension nano-materials-based device was proposed. The bottom-up and top-down combined process were used for constructing CNT-array-based device and ZnO nanowire device. The electrical characteristics of the 1D nano-materials-based devices were also investigated. The measurement results of electrical characteristics demonstrate that it is ohm electrical contact behavior between the nano-material and micro-electrodes in the proposed device which also have the field effect. The proposed 1D nano-material-based device shows the application potential in the sensing fields.
DOE Office of Scientific and Technical Information (OSTI.GOV)
N /A
2002-07-30
The National Nuclear Security Administration (NNSA) has assigned a continuing role to Los Alamos National Laboratory (LANL) in carrying out NNSAs national security mission. To enable LANL to continue this enduring responsibility requires that NNSA maintain the capabilities and capacities required in support of its national mission assignments at LANL. To carry out its Congressionally assigned mission requirements, NNSA must maintain a safe and reliable infrastructure at LANL. Upgrades to the various utility services at LANL have been ongoing together with routine maintenance activities over the years. However, the replacement of a certain portion of natural gas service transmission pipelinemore » is now necessary as this delivery system element has been operating well beyond its original design life for the past 20 to 30 years and components of the line are suffering from normal stresses, strains, and general failures. The Proposed Action is to grant an easement to the Public Service Company of New Mexico (PNM) to construct, operate, and maintain approximately 15,000 feet (4,500 meters) of 12-inch (in.) (30-centimeter [cm]) coated steel natural gas transmission mainline on NNSA-administered land within LANL along Los Alamos Canyon. The new gas line would begin at the existing valve setting located at the bottom of Los Alamos Canyon near the Los Alamos County water well pump house and adjacent to the existing 12-in. (30-cm) PNM gas transmission mainline. The new gas line (owned by PNM) would then cross the streambed and continue east in a new easement obtained by PNM from the NNSA, paralleling the existing electrical power line along the bottom of the canyon. The gas line would then turn northeast near State Road (SR) 4 and be connected to the existing 12-in. (30-cm) coated steel gas transmission mainline, located within the right-of-way (ROW) of SR 502. The Proposed Action would also involve crossing a streambed twice. PNM would bore under the streambed for pipe installation. PNM would also construct and maintain a service road along the pipeline easement. In addition, when construction is complete, the easement would be reseeded. Portions of the Proposed Action are located within potential roosting and nesting habitat for the Mexican spotted owl (Strix occidentalis lucida), a Federally protected threatened species. Surveys over the last seven years have identified no owls within this area. The Proposed Action would be conducted according to the provisions of the LANL Threatened and Endangered Species Habitat Management Plan. Effects would not be adverse to either individuals or potential critical habitat for protected species. Cultural resources within the vicinity of the proposed easement would be avoided with the exception of an historic trail. However, the original trail has been affected by previous activities and no longer has sufficient historical value to be eligible for listing on the National Register of Historic Places. Minimal undisturbed areas would be involved in the Proposed Action. Most of the proposed easement follows an established ROW for the existing electrical power line. There are several potentially contaminated areas within Los Alamos Canyon; however, these areas would be avoided, where possible, or, if avoidance isn't possible or practicable under the Proposed Action, the contaminated areas would be sampled and remediated in accordance with New Mexico Environment Department requirements before construction.« less
Lin, Na; Chen, Hanning; Jing, Shikai; Liu, Fang; Liang, Xiaodan
2017-03-01
In recent years, symbiosis as a rich source of potential engineering applications and computational model has attracted more and more attentions in the adaptive complex systems and evolution computing domains. Inspired by different symbiotic coevolution forms in nature, this paper proposed a series of multi-swarm particle swarm optimizers called PS 2 Os, which extend the single population particle swarm optimization (PSO) algorithm to interacting multi-swarms model by constructing hierarchical interaction topologies and enhanced dynamical update equations. According to different symbiotic interrelationships, four versions of PS 2 O are initiated to mimic mutualism, commensalism, predation, and competition mechanism, respectively. In the experiments, with five benchmark problems, the proposed algorithms are proved to have considerable potential for solving complex optimization problems. The coevolutionary dynamics of symbiotic species in each PS 2 O version are also studied respectively to demonstrate the heterogeneity of different symbiotic interrelationships that effect on the algorithm's performance. Then PS 2 O is used for solving the radio frequency identification (RFID) network planning (RNP) problem with a mixture of discrete and continuous variables. Simulation results show that the proposed algorithm outperforms the reference algorithms for planning RFID networks, in terms of optimization accuracy and computation robustness.
NASA Astrophysics Data System (ADS)
Falcone, Abe
In the coming years, X-ray astronomy will require new soft X-ray detectors that can be read very quickly with low noise and can achieve small pixel sizes over a moderately large focal plane area. These requirements will be present for a variety of X-ray missions that will attempt to address science that was highly ranked by the 2010 Decadal Survey, including missions with science that overlaps with that of IXO and Athena, as well as other missions addressing science topics beyond those of IXO and Athena. An X-ray Surveyor mission was recently chosen by NASA for study by a Science & Technology Definition Team (STDT) so it can be considered as an option for an upcom-ing flagship mission. A mission such as this was endorsed by the NASA long term planning document entitled "Enduring Quests, Daring Visions," and a detailed description of one possible reali-zation of such a mission has been referred to as SMART-X, which was described in a recent NASA RFI response. This provides an example of a future mission concept with these requirements since it has high X-ray throughput and excellent spatial resolution. We propose to continue to modify current active pixel sensor designs, in particular the hybrid CMOS detectors that we have been working with for several years, and implement new in-pixel technologies that will allow us to achieve these ambitious and realistic requirements on a timeline that will make them available to upcoming X-ray missions. This proposal is a continuation of our program that has been work-ing on these developments for the past several years. The first 3 years of the program led to the development of a new circuit design for each pixel, which has now been shown to be suitable for a larger detector array. The proposed activity for the next four years will be to incorporate this pixel design into a new design of a full detector array (2k×2k pixels with digital output) and to fabricate this full-sized device so it can be thoroughly tested and characterized.
Evaluation of image-assisted forest monitoring: A simulation
Francis Roesch; John Coulston; Paul Van Deusen; Rafal Podlaski
2015-01-01
Fiscal uncertainties can sometimes affect national continuous forest monitoring efforts. One solution of interest is to lengthen the time it takes to collect a âfull setâ of plot data from five to 10 years in order to reduce costs. Here, we investigate using ancillary information to partially offset this proposed solutionâs negative effects. We focus our discussion on...
ERIC Educational Resources Information Center
Southern Regional Education Board (SREB), 2010
2010-01-01
While some experts say that technically the recession is over, states are still wrestling with several years of budget reductions, little --if any--revenue growth, and the increasing costs of providing services. Legislatures are continuing to shore up budgets with federal recovery funds and, in some cases, they shifted reserves from dedicated…
ERIC Educational Resources Information Center
Wilson, Patricia A.
2008-01-01
At four-year colleges and universities, particularly those at which either master's degrees or doctoral degrees are the highest degrees conferred, women continue to be underrepresented in the ranks of tenured faculty. At one time, the disparity could be explained by the paucity of women who had earned doctoral degrees and were otherwise qualified…
Why are breastfeeding rates low in Lebanon? a qualitative study
2011-01-01
Background Breastfeeding is a cost-effective public health intervention that reduces infant morbidity and mortality in developing countries. In Lebanon, breastfeeding exclusivity and continuation rates are disappointingly low. This qualitative study aims at identifying barriers and promoters of breastfeeding in the Lebanese context by exploring mothers' perceptions and experiences in breastfeeding over a one year period. Methods We conducted focus group discussions in three hospitals in Beirut, Lebanon, and followed up 36 breastfeeding mothers with serial in-depth interviews for one year post-partum or until breastfeeding discontinuation. Results Themes generated from baseline interviews revealed several positive and negative perceptions of breastfeeding. Longitudinal follow up identified insufficient milk, fear of weight gain or breast sagging, pain, sleep deprivation, exhaustion, or maternal employment, as reasons for early breastfeeding discontinuation. Women who continued breastfeeding for one year were more determined to succeed and overcome any barrier, relying mostly on family support and proper time management. Conclusions Increasing awareness of future mothers about breast feeding difficulties, its benefits to children, mothers, and society at large may further promote breastfeeding, and improve exclusivity and continuation rates in Lebanon. A national strategy for early intervention during school years to increase young women's awareness may improve their self-confidence and determination to succeed in breastfeeding later. Moreover, prolonging maternity leave, having day-care facilities at work, creation of lactation peer support groups and hotlines, and training of doctors and nurses in proper lactation support may positively impact breastfeeding exclusivity and continuation rates. Further research is needed to assess the effectiveness of proposed interventions in the Lebanese context. PMID:21878101
Why are breastfeeding rates low in Lebanon? A qualitative study.
Nabulsi, Mona
2011-08-30
Breastfeeding is a cost-effective public health intervention that reduces infant morbidity and mortality in developing countries. In Lebanon, breastfeeding exclusivity and continuation rates are disappointingly low. This qualitative study aims at identifying barriers and promoters of breastfeeding in the Lebanese context by exploring mothers' perceptions and experiences in breastfeeding over a one year period. We conducted focus group discussions in three hospitals in Beirut, Lebanon, and followed up 36 breastfeeding mothers with serial in-depth interviews for one year post-partum or until breastfeeding discontinuation. Themes generated from baseline interviews revealed several positive and negative perceptions of breastfeeding. Longitudinal follow up identified insufficient milk, fear of weight gain or breast sagging, pain, sleep deprivation, exhaustion, or maternal employment, as reasons for early breastfeeding discontinuation. Women who continued breastfeeding for one year were more determined to succeed and overcome any barrier, relying mostly on family support and proper time management. Increasing awareness of future mothers about breast feeding difficulties, its benefits to children, mothers, and society at large may further promote breastfeeding, and improve exclusivity and continuation rates in Lebanon. A national strategy for early intervention during school years to increase young women's awareness may improve their self-confidence and determination to succeed in breastfeeding later. Moreover, prolonging maternity leave, having day-care facilities at work, creation of lactation peer support groups and hotlines, and training of doctors and nurses in proper lactation support may positively impact breastfeeding exclusivity and continuation rates. Further research is needed to assess the effectiveness of proposed interventions in the Lebanese context.
Fiscal Year 2013 Trails Management Program Mitigation Action Plan Annual Report, October 2013
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pava, Daniel S.
This Trails Management Program Mitigation Action Plan Annual Report (Trails MAPAR) has been prepared for the Department of Energy (DOE)/National Nuclear Security Administration (NNSA) as part of implementing the 2003 Final Environmental Assessment for the Proposed Los Alamos National Laboratory Trails Management Program (DOE 2003). The Trails Mitigation Action Plan (MAP) is now a part of the Site-Wide Environmental Impact Statement for the Continued Operation of Los Alamos National Laboratory (DOE/EIS 0380) Mitigation Action Plan (2008 SWEIS MAP) (DOE 2008). The MAP provides guidance for the continued implementation of the Trails Management Program at Los Alamos National Laboratory (LANL) andmore » integration of future mitigation actions into the 2008 SWEIS MAP to decrease impacts associated with recreational trails use at LANL. This eighth MAPAR includes a summary of Trails Management Program activities and actions during Fiscal Year (FY) 2013, from October 2012 through September 2013.« less
NASA Astrophysics Data System (ADS)
Falcone, Abe
In the coming years, X-ray astronomy will require new soft X-ray detectors that can be read very quickly with low noise and can achieve small pixel sizes over a moderately large focal plane area. These requirements will be present for a variety of X-ray missions that will attempt to address science that was highly ranked by the Decadal Review, including missions with science that over-laps with that of IXO and ATHENA, as well as other missions addressing science topics beyond those of IXO and ATHENA. An X-ray Surveyor mission was recently endorsed by the NASA long term planning document entitled "Enduring Quests, Daring Visions," and a detailed description of one possible realization of such a mission has been referred to as SMART-X, which was described in a recent NASA RFI response. This provides an example of a future mission concept with these requirements since it has high X-ray throughput and excellent spatial resolution. We propose to continue to modify current active pixel sensor designs, in particular the hybrid CMOS detectors that we have been working with for several years, and implement new in-pixel technologies that will allow us to achieve these ambitious and realistic requirements on a timeline that will make them available to upcoming X-ray missions. This proposal is a continuation of our program that has been working on these developments for the past several years.
Code of Federal Regulations, 2014 CFR
2014-04-01
... Notice by a self-regulatory organization of proposed admission to or continuance in membership or... statutory disqualification. (1) Any self-regulatory organization proposing, conditionally or unconditionally... with a member of, a self-regulatory organization, and the terms and conditions of the proposed...
Code of Federal Regulations, 2013 CFR
2013-04-01
... Notice by a self-regulatory organization of proposed admission to or continuance in membership or... statutory disqualification. (1) Any self-regulatory organization proposing, conditionally or unconditionally... with a member of, a self-regulatory organization, and the terms and conditions of the proposed...
Code of Federal Regulations, 2011 CFR
2011-04-01
... Notice by a self-regulatory organization of proposed admission to or continuance in membership or... statutory disqualification. (1) Any self-regulatory organization proposing, conditionally or unconditionally... with a member of, a self-regulatory organization, and the terms and conditions of the proposed...
Code of Federal Regulations, 2010 CFR
2010-04-01
... Notice by a self-regulatory organization of proposed admission to or continuance in membership or... statutory disqualification. (1) Any self-regulatory organization proposing, conditionally or unconditionally... with a member of, a self-regulatory organization, and the terms and conditions of the proposed...
Code of Federal Regulations, 2012 CFR
2012-04-01
... Notice by a self-regulatory organization of proposed admission to or continuance in membership or... statutory disqualification. (1) Any self-regulatory organization proposing, conditionally or unconditionally... with a member of, a self-regulatory organization, and the terms and conditions of the proposed...
International Space Weather Initiative (ISWI)
NASA Technical Reports Server (NTRS)
Davila, Joseph M.; Gopalswamy, Nat; Thompson, Barbara
2009-01-01
The International Heliophysical Year (IHY), an international program of scientific collaboration to understand the external drivers of planetary environments, has come to an end. The IHY was a major international event of great interest to the member States, which involved the deployment of new instrumentation, new observations from the ground and in space, and an education component. We propose to continue the highly successful collaboration between the heliophysics science community and the United Nations Basic Space Science (UNBSS) program. One of the major thrust of the IHY was to deploy arrays of small instruments such as magnetometers, radio antennas, GPS receivers, all-sky cameras, particle detectors, etc. around the world to provide global measurements of heliospheric phenomena. The United Nations Basic Space Science Initiative (UNBSSI) played a major role in this effort. Scientific teams were organized through UNBSS, which consisted of a lead scientist who provided the instruments or fabrication plans for instruments in the array. As a result of the this program, scientists from UNBSS member states now participate in the instrument operation, data collection, analysis, and publication of scientific results, working at the forefront of science research. As part of this project, support for local scientists, facilities and data acquisition is provided by the host nation. In addition, support at the Government level is provided for local scientists to participate. Building on momentum of the IHY, we propose to continue the highly successful collaboration with the UNBSS program to continue the study of universal processes in the solar system that affect the interplanetary and terrestrial environments, and to continue to coordinate the deployment and operation of new and existing instrument arrays aimed at understanding the impacts of Space Weather on Earth and the near-Earth environment. Toward this end, we propose a new program, the International Space Weather Initiative (ISWI).
International Space Weather Initiative (ISWI)
NASA Technical Reports Server (NTRS)
Davila, Joseph; Gopalswamy, Nathanial; Thompson, Barbara
2010-01-01
The International Heliophysical Year (IHY), an international program of scientific collaboration to understand the external drivers of planetary environments, has come to an end. The IHY was a major international event of great interest to the member States, which involved the deployment of new instrumentation, new observations from the ground and in space, and an education component. We propose to continue the highly successful collaboration between the heliophysics science community and the United Nations Basic Space Science (UNBSS) program. One of the major thrust of the IHY was to deploy arrays of small instruments such as magnetometers, radio antennas, GPS receivers, all-sky cameras, particle detectors, etc. around the world to provide global measurements of heliospheric phenomena. The United Nations Basic Space Science Initiative (UNBSSI) played a major role in this effort. Scientific teams were organized through UNBSS, which consisted of a lead scientist who provided the instruments or fabrication plans for instruments in the array. As a result of the this program, scientists from UNBSS member states now participate in the instrument operation, data collection, analysis, and publication of scientific results, working at the forefront of science research. As part of this project, support for local scientists, facilities and data acquisition is provided by the host nation. In addition, support at the Government level is provided for local scientists to participate. Building on momentum of the IHY, we propose to continue the highly successful collaboration with the UNBSS program to continue the study of universal processes in the solar system that affect the interplanetary and terrestrial environments, and to continue to coordinate the deployment and operation of new and existing instrument arrays aimed at understanding the impacts of Space Weather on Earth and the near-Earth environment. Toward this end, we propose a new program, the International Space Weather Initiative (ISWI).
Proposed U.S. Environmental Protection Agency Budget Shows Belt-Tightening
NASA Astrophysics Data System (ADS)
Showstack, Randy
2011-03-01
President Barack Obama's proposed fiscal year (FY) 2012 budget for the Environmental Protection Agency (EPA) is $8.97 billion, a 13% decrease from the agency's FY 2010 enacted budget of $10.3 billion. While Congress has approved a moderate continuing resolution (CR) to fund the federal government until 18 March, the House of Representatives also has passed a CR (House Resolution 1; HR 1) that would call for sharp cuts to the budget for EPA and other agencies for the current fiscal year (2011). EPA administrator Lisa Jackson acknowledged the difficult budget situation during a 14 February teleconference. The proposed budget “reflects the tough choices needed for our nation's short- and long-term fiscal health and allows EPA to maintain its fundamental mission of protecting human health and the environment,” she said. “This budget focuses our resources on the most urgent health and environmental challenges we face. Though it includes significant cuts, it provides EPA with what we need to fundamentally protect the health of the American people,” Jackson added.
NASA Technical Reports Server (NTRS)
Zaretsky, Erwin V.
1990-01-01
The requirement for long-term, reliable operation of aerospace mechanisms has, with a few exceptions, pushed the state of the art in tribology. Space mission life requirements in the early 1960s were generally 6 months to a year. The proposed U.S. space station schedule to be launched in the 1990s must be continuously usable for 10 to 20 years. Liquid lubrication systems are generally used for mission life requirements longer than a year. Although most spacecraft or satellites have reached their required lifetimes without a lubrication-related failure, the application of liquid lubricants in the space environment presents unique challenges. The state of the art of liquid lubrication in space as well as the problems and their solutions are reviewed.
A Purpose-Driven Fourth Year of Medical School.
Dewan, Mantosh; Norcini, John
2017-10-03
The fourth year of medical school has been repeatedly found to be ineffective, and concerns exist about its purpose and academic quality, as well as grade inflation. Since Flexner, the purpose of undergraduate medical training has moved from readiness for independent practice to readiness for postgraduate training. However, training directors report that medical graduates are inadequately prepared to enter residency. The authors propose a fourth year with two components: first, a yearlong, longitudinal ambulatory experience of at least three days each week on an interprofessional team with consistent faculty supervision and mentoring, increasing independence, and a focus on education; and second, rigorous clinical-scales-based assessment of meaningful outcomes.In the proposed model, the medical student has generous time with a limited panel of patients, and increasing autonomy, with faculty moving from supervising physicians to collaborating physicians. There is regular assessment and formative feedback. This more independent, longitudinal clinical experience uniquely allows assessment of the most meaningful work-based performance outcomes-that is, patient outcomes assessed by validated clinical scales. The proposed fourth year will require a realignment of resources and faculty time; however, models already exist. Barriers and possible solutions are discussed.A purpose-driven, assessment-rich fourth year with patient and supervisor continuity will provide real-world experience, making medical graduates more competent and confident on the first day of residency. Use of clinical scales will also allow educators new confidence that the performance-based competence of these more experienced and expert graduates leads to demonstrable collaboration, healing, and good patient outcomes.
7 CFR 1794.25 - Proposals normally requiring an EIS.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 12 2010-01-01 2010-01-01 false Proposals normally requiring an EIS. 1794.25 Section 1794.25 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Classification of Proposals...
7 CFR 1794.25 - Proposals normally requiring an EIS.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 12 2013-01-01 2013-01-01 false Proposals normally requiring an EIS. 1794.25 Section 1794.25 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Classification of Proposals...
7 CFR 1794.25 - Proposals normally requiring an EIS.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 12 2014-01-01 2013-01-01 true Proposals normally requiring an EIS. 1794.25 Section 1794.25 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Classification of Proposals...
LAI, FAPAR and FCOVER products derived from AVHRR long time series: principles and evaluation
NASA Astrophysics Data System (ADS)
Verger, A.; Baret, F.; Weiss, M.; Lacaze, R.; Makhmara, H.; Pacholczyk, P.; Smets, B.; Kandasamy, S.; Vermote, E.
2012-04-01
Continuous and long term global monitoring of the terrestrial biosphere has draught an intense interest in the recent years in the context of climate and global change. Developing methodologies for generating historical data records from data collected with different satellite sensors over the past three decades by taking benefits from the improvements identified in the processing of the new generation sensors is a new central issue in remote sensing community. In this context, the Bio-geophysical Parameters (BioPar) service within Geoland2 project (http://www.geoland2.eu) aims at developing pre-operational infrastructures for providing global land products both in near real time and off-line mode with long time series. In this contribution, we describe the principles of the GEOLAND algorithm for generating long term datasets of three key biophysical variables, leaf area index (LAI), Fraction of Absorbed Photosynthetic Active Radiation (FAPAR) and cover fraction (FCOVER), that play a key role in several processes, including photosynthesis, respiration and transpiration. LAI, FAPAR and FCOVER are produced globally from AVHRR Long Term Data Record (LTDR) for the 1981-2000 period at 0.05° spatial resolution and 10 days temporal sampling frequency. The proposed algorithm aims to ensure robustness of the derived long time series and consistency with the ones developed in the recent years, and particularly with GEOLAND products derived from VEGETATION sensor. The approach is based on the capacity of neural networks to learn a particular biophysical product (GEOLAND) from reflectances from another sensor (AVHRR normalized reflectances in the red and near infrared bands). Outliers due to possible cloud contamination or residual atmospheric correction are iteratively eliminated. Prior information based on the climatology is used to get more robust estimates. A specific gap filing and smoothing procedure was applied to generate continuous and smooth time series of decadal products. Finally, quality assessment information as well as tentative quantitative uncertainties were proposed. The comparison of the resulting AVHRR LTDR products with actual GEOLAND series derived from VEGETATION demonstrates that they are very consistent, providing continuous time series of global observations of LAI, FAPAR and FCOVER for the last 30-year period, with continuation after 2011.
NASA Astrophysics Data System (ADS)
Valent, Peter; Paquet, Emmanuel
2017-09-01
A reliable estimate of extreme flood characteristics has always been an active topic in hydrological research. Over the decades a large number of approaches and their modifications have been proposed and used, with various methods utilizing continuous simulation of catchment runoff, being the subject of the most intensive research in the last decade. In this paper a new and promising stochastic semi-continuous method is used to estimate extreme discharges in two mountainous Slovak catchments of the rivers Váh and Hron, in which snow-melt processes need to be taken into account. The SCHADEX method used, couples a precipitation probabilistic model with a rainfall-runoff model used to both continuously simulate catchment hydrological conditions and to transform generated synthetic rainfall events into corresponding discharges. The stochastic nature of the method means that a wide range of synthetic rainfall events were simulated on various historical catchment conditions, taking into account not only the saturation of soil, but also the amount of snow accumulated in the catchment. The results showed that the SCHADEX extreme discharge estimates with return periods of up to 100 years were comparable to those estimated by statistical approaches. In addition, two reconstructed historical floods with corresponding return periods of 100 and 1000 years were compared to the SCHADEX estimates. The results confirmed the usability of the method for estimating design discharges with a recurrence interval of more than 100 years and its applicability in Slovak conditions.
32 CFR 204.7 - Legislative proposals.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Legislative proposals. 204.7 Section 204.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED... Counsel, 1600 Defense Pentagon, Washington, DC 20301-1600. Proposals to remove user fee restrictions or...
Kvitland, Levi Roestad; Melle, Ingrid; Aminoff, Sofie Ragnhild; Demmo, Christine; Lagerberg, Trine Vik; Andreassen, Ole Andreas; Ringen, Petter Andreas
2015-02-05
There is limited knowledge about how environmental factors affect the course of bipolar disorder (BD). Cannabis has been proposed as a potential risk factor for poorer course of illness, but the role of cannabis use has not been studied in a first treatment BD I sample. The present study examines the associations between course of illness in first treatment BD I and continued cannabis use, from baseline to one year follow up. Patients (N = 62) with first treatment DSM-IV BD I were included as part of the Thematically Organized Psychosis study (TOP), and completed interviews and self-report questionnaires at both baseline and follow up. Cannabis use within the last six months at baseline and use between baseline and follow up ("continued use") was recorded. After controlling for confounders, continued cannabis use was significantly associated with elevated mood (YMRS) and inferior global functioning (GAF-F) at follow up. Elevated mood mediated the effect of cannabis use on global functioning. These results suggest that cannabis use has clinical implications for the early course of BD by increasing mood level. More focus on reducing cannabis use in clinical settings seems to be useful for improving outcome in early phase of the disorder.
ERIC Educational Resources Information Center
Mars Hill Coll., NC.
On October 3, 1972 the faculty of Mars Hill College approved the extension of the present core curriculum and the modified 4-1-4 calendar through the 1973-74 academic year. The faculty further asked that the study of the competence-based curriculum be continued. This document contains a partial list of the proposals produced by the ongoing review…
2013-10-01
identify common genetic variations (i.e., single nucleotide polymorphisms [ SNPs ] and haplotypes) in cytokine genes, as well demographic, clinical, and...Center. The purpose of the proposed project is to identify common genetic variations (i.e., single nucleotide polymorphisms [ SNPs ] and haplotypes) in...research team continues to meet monthly to discuss progress with regards to recruitment, enrollment, and data collection. Training in Genetics In year
ERIC Educational Resources Information Center
Nienhusser, H. Kenny; Oshio, Toko
2017-01-01
High school students' accuracy in estimating the cost of college (AECC) was examined by utilizing a new methodological approach, the absolute-deviation-continuous construct. This study used the High School Longitudinal Study of 2009 (HSLS:09) data and examined 10,530 11th grade students in order to measure their AECC for 4-year public and private…
An interval programming model for continuous improvement in micro-manufacturing
NASA Astrophysics Data System (ADS)
Ouyang, Linhan; Ma, Yizhong; Wang, Jianjun; Tu, Yiliu; Byun, Jai-Hyun
2018-03-01
Continuous quality improvement in micro-manufacturing processes relies on optimization strategies that relate an output performance to a set of machining parameters. However, when determining the optimal machining parameters in a micro-manufacturing process, the economics of continuous quality improvement and decision makers' preference information are typically neglected. This article proposes an economic continuous improvement strategy based on an interval programming model. The proposed strategy differs from previous studies in two ways. First, an interval programming model is proposed to measure the quality level, where decision makers' preference information is considered in order to determine the weight of location and dispersion effects. Second, the proposed strategy is a more flexible approach since it considers the trade-off between the quality level and the associated costs, and leaves engineers a larger decision space through adjusting the quality level. The proposed strategy is compared with its conventional counterparts using an Nd:YLF laser beam micro-drilling process.
40 CFR 77.4 - Administrator's action on proposed offset plans.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Administrator's action on proposed offset plans. 77.4 Section 77.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) EXCESS EMISSIONS § 77.4 Administrator's action on proposed offset plans. (a...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-20
...The EPA has made a proposed determination that a reduction in recurring expenditures of non-Federal funds for the Lane Regional Air Protection Agency (LRAPA) in Eugene, Oregon is a result of agency wide non-selective reductions in expenditures. This determination, when final, will permit the LRAPA to continue to receive grant funding under Section 105 of the Clean Air Act for the state fiscal year (SFY) 2014. This determination will also reset the LRAPA required maintenance of effort level for SFY 2012 and 2013 to reflect the non-selective reductions made to address reductions in revenue due to adverse economic conditions in Lane County, Oregon.
Australian university proposes academic program changes
NASA Astrophysics Data System (ADS)
Zielinski, Sarah
The University of Melbourne in Australia has adopted a 10-year plan to create a U.S.-style of education where undergraduate university students would first have to complete a three-year general degree in science or the arts before being allowed to continue onto graduate or professional studies. Unlike in the United States, most Australian students are able to move from secondary school directly into professional studies.A major change for Earth science students would be the replacement of the one-year Bachelor of Science Honours with a two-year Masters program. According to Janet Hergt, head of the university's School of Earth Sciences, the longer program could allow students more time to develop and complete research projects, and would provide them with a better understanding of Ph.D.studies.
Law, A; Yu, J S; Wang, W; Lin, J; Lynen, R
2017-09-01
Three measures to assess the provision of effective contraception methods among reproductive-aged women have recently been endorsed for national public reporting. Based on these measures, this study examined real-world trends and regional variations of contraceptive provision in a commercially insured population in the United States. Women 15-44years old with continuous enrollment in each year from 2005 to 2014 were identified from a commercial claims database. In accordance with the proposed measures, percentages of women (a) provided most effective or moderately effective (MEME) methods of contraception and (b) provided a long-acting reversible contraceptive (LARC) method were calculated in two populations: women at risk for unintended pregnancy and women who had a live birth within 3 and 60days of delivery. During the 10-year period, the percentages of women at risk for unintended pregnancy provided MEME contraceptive methods increased among 15-20-year-olds (24.5%-35.9%) and 21-44-year-olds (26.2%-31.5%), and those provided a LARC method also increased among 15-20-year-olds (0.1%-2.4%) and 21-44-year-olds (0.8%-3.9%). Provision of LARC methods increased most in the North Central and West among both age groups of women. Provision of MEME contraceptives and LARC methods to women who had a live birth within 60days postpartum also increased across age groups and regions. This assessment indicates an overall trend of increasing provision of MEME contraceptive methods in the commercial sector, albeit with age group and regional variations. If implemented, these proposed measures may have impacts on health plan contraceptive access policy. Copyright © 2017 Elsevier Inc. All rights reserved.
40 CFR 78.17 - Proposed findings and conclusions and supporting brief.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Proposed findings and conclusions and supporting brief. 78.17 Section 78.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPEAL PROCEDURES § 78.17 Proposed findings and conclusions and supporting...
The Properties of Single Interstellar Clouds Cycle 2
NASA Astrophysics Data System (ADS)
Hobbs, Lewis
1991-07-01
IN THIS CONTINUATION PROPOSAL, WE PROPOSE TO USE THE ECHELLEAND 160M GRATINGS OF THE HIGH RESOLUTION SPECTROGRAPH TO OBSERVE THE PZROFILES OF INTERSTELLAR ABSORPTION LINES, DURING THE SECOND YEAR OF A TWO-YEAR PROGRAM. IN THE TWO CYCLES TOGETHER, THE COLUMN DENSITES OF 17 NEUTRAL OR IONIZED FORMS OF THE ELEMENTS C,N,O,Mg,Si,P,S,Fe, AND Zn WILL BE MEASURED IN THE APPROXIMATELY 100 INDIVIDUAL INTERSTELLAR CLOUDS ALONG THE LIGHT PATHS TO 12 BRIGHT, BROAD-LINED STARS OF EARLY SPECTRAL TYPE WITHIN 1 KPC OF THE SUN. THE PRIMARY PURPOSE OF THE OBSERVATIONS IS TO DETERMINE MORE ACCURATELY THAN WAS HITHERTO POSSIBLE THE FUNDAMENTAL PHYSICAL PROPERTIES OF THE RESOLVED CLOUDS, INCLUDING LINEAR SIZE, TEMPERATURE, TOTAL DENSITY, FRACTIONAL IONIZATION AND THE RELATIVE ABUNDANCES OF THE 9 SELECTED ELEMENTS. THIS SECOND-YEAR PROGRAM CONSISTS OF ECH-B AND G160M OBSERVATIONS OF EACH OF 4 STARS AT 21 OR MORE WAVELENGTHS, AND OF A SUBSET OF THESE OBSERVATIONS FOR A FIFTH STAR, PI SCO. PROGRAMS 2251 AND 3993 SHOULD BE CONSULTED FOR DETAILS OF THE PREVIOUS OBSERVATIONS OBTAINED DURING CYCLE 1.
MMI's Metadata and Vocabulary Solutions: 10 Years and Growing
NASA Astrophysics Data System (ADS)
Graybeal, J.; Gayanilo, F.; Rueda-Velasquez, C. A.
2014-12-01
The Marine Metadata Interoperability project (http://marinemetadata.org) held its public opening at AGU's 2004 Fall Meeting. For 10 years since that debut, the MMI guidance and vocabulary sites have served over 100,000 visitors, with 525 community members and continuous Steering Committee leadership. Originally funded by the National Science Foundation, over the years multiple organizations have supported the MMI mission: "Our goal is to support collaborative research in the marine science domain, by simplifying the incredibly complex world of metadata into specific, straightforward guidance. MMI encourages scientists and data managers at all levels to apply good metadata practices from the start of a project, by providing the best guidance and resources for data management, and developing advanced metadata tools and services needed by the community." Now hosted by the Harte Research Institute at Texas A&M University at Corpus Christi, MMI continues to provide guidance and services to the community, and is planning for marine science and technology needs for the next 10 years. In this presentation we will highlight our major accomplishments, describe our recent achievements and imminent goals, and propose a vision for improving marine data interoperability for the next 10 years, including Ontology Registry and Repository (http://mmisw.org/orr) advancements and applications (http://mmisw.org/cfsn).
NASA Astrophysics Data System (ADS)
Min, Huang; Na, Cai
2017-06-01
These years, ant colony algorithm has been widely used in solving the domain of discrete space optimization, while the research on solving the continuous space optimization was relatively little. Based on the original optimization for continuous space, the article proposes the improved ant colony algorithm which is used to Solve the optimization for continuous space, so as to overcome the ant colony algorithm’s disadvantages of searching for a long time in continuous space. The article improves the solving way for the total amount of information of each interval and the due number of ants. The article also introduces a function of changes with the increase of the number of iterations in order to enhance the convergence rate of the improved ant colony algorithm. The simulation results show that compared with the result in literature[5], the suggested improved ant colony algorithm that based on the information distribution function has a better convergence performance. Thus, the article provides a new feasible and effective method for ant colony algorithm to solve this kind of problem.
Vasudevan, Srivathsan; Chen, George C K; Ahluwalia, Balpreet Singh
2008-12-01
Photothermal response (PTR) is an established pump and probe technique for real-time sensing of biological assays. Continuous and selective PTR monitoring is difficult owing to the Brownian motion changing the relative position of the target with respect to the beams. Integration of laser trapping with PTR is proposed as a solution. The proposed method is verified on red polystyrene microparticles. PTR is continuously monitored for 30 min. Results show that the mean relaxation time variation of the acquired signals is less than 5%. The proposed method is then applied to human red blood cells for continuous and selective PTR.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-11
... Change To Amend Rule 640, Continuing Education for Registered Persons and Adopt a Corresponding Fee... Substance of the Proposed Rule Change The Exchange proposes to amend Rule 640, Continuing Education for... 640. Continuing Education for Registered Persons (a) Regulatory Element (1) Requirements--No member...
Continuation of the Resource Conservation and Development Program Raises Questions.
1981-08-11
almost any measure proposed to be counted toward helping accomplish the plan’s objectives and furthering its goals. SOME PLANS ARE NOT UP TO DATE...FUNDS THEY HAD RECEIVED AS OF SEPTEMBER 1980 Year Project project Amount area (State) authorized received (000 omitted) Sangre de Cristo (Colo.) 1968...Minn.) 1975 711 Northeast (miss.) 1967 4,605 Southeast (Miss.) 1971 1,868 Top of the Ozarks (Mo.) 1965 1,954 Bitter Root Valley ( Mont .) 1965 2,605
1994-05-01
concludes that "decisions on doctrine ... become a precondition and guidance for integrating the research and development of new technologies .ř One...recognition that in developing doctrine, some weapons will not be effective until other technological advances occur. The machine gun, for instance, had...civilian and military level with the development of doctrine and technology . In the interwar years, for example, de Gaulle’s proposal for a professional
Reconstructing the past outburst history of Eta Carinae from WFPC2 proper motions
NASA Astrophysics Data System (ADS)
Smith, Nathan
2016-10-01
The HST archive contains multiple epochs of WFPC2 images of the nebula around Eta Carinae taken over a 15-year timespan, although only the earliest few years of data have been analyzed and published. The fact that all these images were taken with the same instrument, with the same pixel sampling and field distortion, makes them an invaluable resource for accurately measuring the expanding ejecta. The goal of a previously accepted AR proposal was to analyze the full set of appropriate continuum-filter HST images to place precise constraints on the avereage ejection date of the Homunculus Nebula; this analysis is now complete (Smith et al 2016) and the nebula appears to have been ejected in the second half of 1847. Here we propose to continue this project by constraining the motion of the more extended and much older Outer Ejecta around Eta Carinae. Older material outside the main bipolar nebula traces previous major outbursts of the star with no recorded historical observations. We propose an ambitious reduction and analysis of the complete WFPC2 imaging dataset of Eta Car. These data can reconstruct its violent mass-loss history over the past thousand years. We have already started this by analyzing two epochs of ACS F658N images, and astonishingly, these data suggested two previous eruptions in the 13th and 15th centuries assuming ballistic motion. WFPC2 images will extend the baseline by 10 yr, and critically, more than 2 epochs allow us to measure any deceleration in the ejecta. We will also analyze Doppler shifts in ground-based spectra in order to reconstruct the 3D geometry of past mass ejection. This AR proposal will fund the final year of a PhD thesis.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Socolof, M.L.; Curtis, A.H.; Blasing, T.J.
1995-08-01
DOE needs to continue the safe and efficient management of SNF on ORR, based on the requirement for future SNF storage capacity and implementation of the ROD for the PEIS. DOE is proposing to implement the ROD through proper management of SNF on ORR, including the possible construction and operation of a dry cask storage facility. This report describes the potentially affected environment and analyzes impacts on various resources due to the proposed action. The information provided in this report is intended to support the Environmental Assessment being prepared for the proposed activities. Construction of the dry cask storage facilitymore » would result in minimal or no impacts on groundwater, surface water, and ecological resources. Contaminated soils excavated during construction would result in negligible risk to human health and to biota. Except for noise from trucks and equipment, operation of the dry cask storage facility would not be expected to have any impact on vegetation, wildlife, or rare plants or animals. Noise impacts would be minimal. Operation exposures to the average SNF storage facility worker would not exceed approximately 0.40 mSv/year (40 mrem/year). The off-site population dose within an 80-km (50-mile) radius of ORR from SNF operations would be less than 0.052 person-Sv/year (5.2 person-rem/year). Impacts from incident-free transportation on ORR would be less than 1.36 X 10{sup -4} occupational fatal cancers and 4.28 X 10{sup -6} public fatal cancers. Credible accident scenarios that would result in the greatest probable risks would cause less than one in a million cancer fatalities to workers and the public.« less
Continuous Human Action Recognition Using Depth-MHI-HOG and a Spotter Model
Eum, Hyukmin; Yoon, Changyong; Lee, Heejin; Park, Mignon
2015-01-01
In this paper, we propose a new method for spotting and recognizing continuous human actions using a vision sensor. The method is comprised of depth-MHI-HOG (DMH), action modeling, action spotting, and recognition. First, to effectively separate the foreground from background, we propose a method called DMH. It includes a standard structure for segmenting images and extracting features by using depth information, MHI, and HOG. Second, action modeling is performed to model various actions using extracted features. The modeling of actions is performed by creating sequences of actions through k-means clustering; these sequences constitute HMM input. Third, a method of action spotting is proposed to filter meaningless actions from continuous actions and to identify precise start and end points of actions. By employing the spotter model, the proposed method improves action recognition performance. Finally, the proposed method recognizes actions based on start and end points. We evaluate recognition performance by employing the proposed method to obtain and compare probabilities by applying input sequences in action models and the spotter model. Through various experiments, we demonstrate that the proposed method is efficient for recognizing continuous human actions in real environments. PMID:25742172
Shallow Water Optical Water Quality Buoy
NASA Technical Reports Server (NTRS)
Bostater, Charles
1998-01-01
This NASA grant was funded as a result of an unsolicited proposal submission to Kennedy Space Center. The proposal proposed the development and testing of a shallow water optical water quality buoy. The buoy is meant to work in shallow aquatic systems (ponds, rivers, lagoons, and semi-enclosed water areas where strong wind wave action is not a major environmental During the project period of three years, a demonstration of the buoy was conducted. The last demonstration during the project period was held in November, 1996 when the buoy was demonstrated as being totally operational with no tethered communications line. During the last year of the project the buoy was made to be solar operated by large gel cell batteries. Fund limitations did not permit the batteries in metal enclosures as hoped for higher wind conditions, however the system used to date has worked continuously for in- situ operation of over 18 months continuous deployment. The system needs to have maintenance and somewhat continuous operational attention since various components have limited lifetime ages. For example, within the last six months the onboard computer has had to be repaired as it did approximately 6 months after deployment. The spectrograph had to be repaired and costs for repairs was covered by KB Science since no ftmds were available for this purpose after the grant expired. Most recently the computer web page server failed and it is currently being repaired by KB Science. In addition, the cell phone operation is currently being ftmded by Dr. Bostater in order to maintain the system's operation. The above points need to be made to allow NASA to understand that like any sophisticated measuring system in a lab or in the field, necessary funding and maintenance is needed to insure the system's operational state and to obtain quality factor. The proposal stated that the project was based upon the integration of a proprietary and confidential sensor and probe design that was developed by KB Science and Engineering and is currently patented by KB Science. The buoy's purpose was to collected hyperspectral optical signatures for analysis and resulting estimation of water quality parameters such as chlorophyll-a, seston and dissolved organic matter (DOC). The ultimate goal of the project was to develop a buoy that would integrate a probe to measure upwelling light from a source and thus relate this backscattered light to water quality parameters.
Sparacino, Giovanni; Zanon, Mattia; Facchinetti, Andrea; Zecchin, Chiara; Maran, Alberto; Cobelli, Claudio
2012-01-01
Monitoring glucose concentration in the blood is essential in the therapy of diabetes, a pathology which affects about 350 million people around the World (three million in Italy), causes more than four million deaths per year and consumes a significant portion of the budget of national health systems (10% in Italy). In the last 15 years, several sensors with different degree of invasiveness have been proposed to monitor glycemia in a quasi-continuous way (up to 1 sample/min rate) for relatively long intervals (up to 7 consecutive days). These continuous glucose monitoring (CGM) sensors have opened new scenarios to assess, off-line, the effectiveness of individual patient therapeutic plans from the retrospective analysis of glucose time-series, but have also stimulated the development of innovative on-line applications, such as hypo/hyper-glycemia alert systems and artificial pancreas closed-loop control algorithms. In this review, we illustrate some significant Italian contributions, both from industry and academia, to the growth of the CGM sensors research area. In particular, technological, algorithmic and clinical developments performed in Italy will be discussed and put in relation with the advances obtained in the field in the wider international research community. PMID:23202020
Sparacino, Giovanni; Zanon, Mattia; Facchinetti, Andrea; Zecchin, Chiara; Maran, Alberto; Cobelli, Claudio
2012-10-12
Monitoring glucose concentration in the blood is essential in the therapy of diabetes, a pathology which affects about 350 million people around the World (three million in Italy), causes more than four million deaths per year and consumes a significant portion of the budget of national health systems (10% in Italy). In the last 15 years, several sensors with different degree of invasiveness have been proposed to monitor glycemia in a quasi-continuous way (up to 1 sample/min rate) for relatively long intervals (up to 7 consecutive days). These continuous glucose monitoring (CGM) sensors have opened new scenarios to assess, off-line, the effectiveness of individual patient therapeutic plans from the retrospective analysis of glucose time-series, but have also stimulated the development of innovative on-line applications, such as hypo/hyper-glycemia alert systems and artificial pancreas closed-loop control algorithms. In this review, we illustrate some significant Italian contributions, both from industry and academia, to the growth of the CGM sensors research area. In particular, technological, algorithmic and clinical developments performed in Italy will be discussed and put in relation with the advances obtained in the field in the wider international research community.
"I had a good time when I was young": Interpreting descriptions of continuity among older people.
Breheny, Mary; Griffiths, Zoë
2017-04-01
Messages describing how best to age are prominent in gerontological theory, research and the media. These prescriptions for ageing may foster positive experiences in later life; however, they may also obscure the social and situated nature of expectations for ageing well. Continuity Theory proposes ageing well is achieved through continuity of activity and stability of relationships and identity over the life course. Continuity seems adaptive, yet prioritising continuity may not match the expectations, desires and realities of older people. To understand continuity among older people, the present study used interpretative phenomenological analysis (IPA) to analyse transcripts from eleven participants over the age of 79 years. Continuity was important for older people in this study, who described a range of practices that supported internal and external continuity. Participants acknowledged both positive and negative changes in roles and obligations as they aged which impacted on continuity of identity. Continuity of identity was linked both to being 'just like always' and 'just like everyone else'. Examining these accounts shows how they are tied to expectations that older people should both maintain earlier patterns of behaviour while also negotiating changing social expectations for behaviour that are linked to age. These tensions point to the balance between physical, environmental and interpersonal change and the negotiation of social expectations which together structure possibilities for ageing well. Copyright © 2017 Elsevier Inc. All rights reserved.
Analytical Assessment for Transient Stability Under Stochastic Continuous Disturbances
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ju, Ping; Li, Hongyu; Gan, Chun
Here, with the growing integration of renewable power generation, plug-in electric vehicles, and other sources of uncertainty, increasing stochastic continuous disturbances are brought to power systems. The impact of stochastic continuous disturbances on power system transient stability attracts significant attention. To address this problem, this paper proposes an analytical assessment method for transient stability of multi-machine power systems under stochastic continuous disturbances. In the proposed method, a probability measure of transient stability is presented and analytically solved by stochastic averaging. Compared with the conventional method (Monte Carlo simulation), the proposed method is many orders of magnitude faster, which makes itmore » very attractive in practice when many plans for transient stability must be compared or when transient stability must be analyzed quickly. Also, it is found that the evolution of system energy over time is almost a simple diffusion process by the proposed method, which explains the impact mechanism of stochastic continuous disturbances on transient stability in theory.« less
Tan, Ziwen; Qin, Guoyou; Zhou, Haibo
2016-01-01
Outcome-dependent sampling (ODS) designs have been well recognized as a cost-effective way to enhance study efficiency in both statistical literature and biomedical and epidemiologic studies. A partially linear additive model (PLAM) is widely applied in real problems because it allows for a flexible specification of the dependence of the response on some covariates in a linear fashion and other covariates in a nonlinear non-parametric fashion. Motivated by an epidemiological study investigating the effect of prenatal polychlorinated biphenyls exposure on children's intelligence quotient (IQ) at age 7 years, we propose a PLAM in this article to investigate a more flexible non-parametric inference on the relationships among the response and covariates under the ODS scheme. We propose the estimation method and establish the asymptotic properties of the proposed estimator. Simulation studies are conducted to show the improved efficiency of the proposed ODS estimator for PLAM compared with that from a traditional simple random sampling design with the same sample size. The data of the above-mentioned study is analyzed to illustrate the proposed method. PMID:27006375
Persistence of carbon release events through the peak of early Eocene global warmth
NASA Astrophysics Data System (ADS)
Kirtland Turner, Sandra; Sexton, Philip F.; Charles, Christopher D.; Norris, Richard D.
2014-10-01
The Early Eocene Climatic Optimum (53-50 million years ago) was preceded by approximately six million years of progressive global warming. This warming was punctuated by a series of rapid hyperthermal warming events triggered by the release of greenhouse gases. Over these six million years, the carbon isotope record suggests that the events became more frequent but smaller in magnitude. This pattern has been suggested to reflect a thermodynamic threshold for carbon release that was more easily crossed as global temperature rose, combined with a decrease in the size of carbon reservoirs during extremely warm conditions. Here we present a continuous, 4.25-million-year-long record of the stable isotope composition of carbonate sediments from the equatorial Atlantic, spanning the peak of early Eocene global warmth. A composite of this and pre-existing records shows that the carbon isotope excursions that identify the hyperthermals exhibit continuity in magnitude and frequency throughout the approximately 10-million-year period covering the onset, peak and termination of the Early Eocene Climate Optimum. We suggest that the carbon cycle processes behind these events, excluding the largest event, the Palaeocene-Eocene Thermal Maximum (about 56 million years ago), were not exceptional. Instead, we argue that the hyperthermals may reflect orbital forcing of the carbon cycle analogous to the mechanisms proposed to operate in the cooler Oligocene and Miocene.
Medicare+Choice: what lies ahead?
Layne, R Jeffrey
2002-03-01
Health plans have continued to exit the Medicare+Choice program in recent years, despite efforts of Congress and the Centers for Medicare and Medicaid Services (CMS) to reform the program. Congress and CMS therefore stand poised to make additional, substantial reforms to the program. CMS has proposed to consolidate its oversight of the program, extend the due date for Medicare+Choice plans to file their adjusted community rate proposals, revise risk-adjustment processes, streamline the marketing review process, enhance quality-improvement requirements, institute results based performance assessment audits, coordinate policy changes to coincide with contracting cycles, expand its fall advertising campaign for the program, provide better employer-based Medicare options for beneficiaries, and take steps to minimize beneficiary costs. Congressional leaders have proposed various legislative remedies to improve the program, including creation of an entirely new pricing structure for the program based on a competitive bidding process.
Sobel, Mark E; Dreyfus, Jennifer C
2017-01-01
Academic pathology departments will be dramatically affected by proposed United States federal government regulatory initiatives. Pathology research will be substantially altered if proposed changes to the Common Rule (Code of Federal Regulations: Protection of Human Subjects title 45 CFR 46) and regulations governing the return of individual research results are approved and finalized, even more so now that the Precision Medicine initiative has been launched. Together, these changes are disruptive influences on academic pathology research as we know it, straining limited resources and compromising advances in diagnostic and academic pathology. Academic research pathologists will be challenged over the coming years and must demonstrate leadership to ensure the continued availability of and the ethical use of research pathology specimens. Copyright © 2017 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.
Rules regarding the health insurance premium tax credit. Final and temporary regulations.
2014-07-28
This document contains final and temporary regulations relating to the health insurance premium tax credit enacted by the Patient Protection and Affordable Care Act and the Health Care and Education Reconciliation Act of 2010, as amended by the Medicare and Medicaid Extenders Act of 2010, the Comprehensive 1099 Taxpayer Protection and Repayment of Exchange Subsidy Overpayments Act of 2011, and the Department of Defense and Full-Year Continuing Appropriations Act of 2011 and the 3% Withholding Repeal and Job Creation Act. These regulations affect individuals who enroll in qualified health plans through Affordable Insurance Exchanges (Exchanges) and claim the premium tax credit, and Exchanges that make qualified health plans available to individuals. The text of the temporary regulations in this document also serves as the text of proposed regulations set forth in a notice of proposed rulemaking (REG-104579-13) on this subject in the Proposed Rules section in this issue of the Federal Register.
Czarnecki, John B.
2006-01-01
The Grand Prairie Water Users Association, located in Lonoke County, Arkansas, plans to increase ground-water withdrawals from the Mississippi River Valley alluvial aquifer from their current (2005) rate of about 400 gallons per minute to 1,400 gallons per minute (2,016,000 gallons per day). The effect of pumping from a proposed well was simulated using a digital model of ground-water flow. The proposed additional withdrawals were added to an existing pumping cell specified in the model, with increased pumping beginning in 2005, and specified to pump at a total combined rate of 2,016,000 gallons per day for a period of 46 years. In addition, pumping from wells owned by Cabot Water Works, located about 2 miles from the proposed pumping, was added to the model beginning in 2001 and continuing through to the end of 2049. Simulated pumping causes a cone of depression to occur in the alluvial aquifer with a maximum decline in water level of about 8.5 feet in 46 years in the model cell of the proposed well compared to 1998 withdrawals. However, three new dry model cells occur south of the withdrawal well after 46 years. This total water-level decline takes into account the cumulative effect of all wells pumping in the vicinity, although the specified pumping rate from all other model cells in 2005 is less than for actual conditions in 2005. After 46 years with the additional pumping, the water-level altitude in the pumped model cell was about 177.4 feet, which is 41.7 feet higher than 135.7 feet, the altitude corresponding to half of the original saturated thickness of the alluvial aquifer (a metric used to determine if the aquifer should be designated as a Critical Ground-Water Area (Arkansas Natural Resources Commission, 2006)).
Andromeda's SMBH Projected Accretion Rate
NASA Astrophysics Data System (ADS)
Wilson, John
2014-03-01
A formula for calculating the half-life of galaxy clusters is proposed. A galactic half-life is the estimated amount of time that the most massive supermassive black hole (SMBH) in the galaxy cluster will have accreted one half of the mass in the cluster. The calculation is based on a projection of the SMBH continuing its exponentially decreasing rate of accretion that it had in its first 13 billion years. The calculated half-life for the Andromeda SMBH is approximately 1.4327e14 years from the Big Bang. Several proposals have suggested that black holes could be significant factors in the formation of new universes. Part of the verification or falsification of this hypothesis could be done by an N-body simulation. These simulations require an enormous amount of computer power and time. Some plausible projection of the growth of the supermassive black hole is needed to prepare an N-body simulation budget proposal. For now, this method provides an estimate for the growth rate of the Andromeda SMBH and deposition of the outcome of most of the galaxy cluster's mass which is either accreted by the SMBH, lost by ejection from the cluster, or lost in the form of energy.
Entrepreneurship in continuing dental education: a dental school perspective.
Liberto, Vincent N
2005-01-01
The definition of continuing dental education is presented, along with its benefits to the profession. The preeminence of dental schools in providing lifelong learning opportunities and freedom from commercial involvement that existed even twenty years ago has changed. Less than a quarter of CE takes place in school, and the focus there is increasingly on material with deep scientific background and hands-on learning. The newest innovations and those with the greatest commercial potential are taught elsewhere. Proposed changes in the ADA CERP standards would take on a "purist" approach that could place dental schools at a severe disadvantage while allowing "for profit" institutes to flourish and thus further undermine the role dental schools can play in providing quality professional development experiences.
All-printed capacitors with continuous solution dispensing technology
NASA Astrophysics Data System (ADS)
Ge, Yang; Plötner, Matthias; Berndt, Andreas; Kumar, Amit; Voit, Brigitte; Pospiech, Doris; Fischer, Wolf-Joachim
2017-09-01
Printed electronics have been introduced into the commercial markets in recent years. Various printing technologies have emerged aiming to process printed electronic devices with low cost, environmental friendliness, and compatibility with large areas and flexible substrates. The aim of this study is to propose a continuous solution dispensing technology for processing all-printed thin-film capacitors on glass substrates using a leading-edge printing instrument. Among all printing technologies, this study provides concrete proof of the following outstanding advantages of this technology: high tolerance to inks, high throughput, low cost, and precise pattern transfers. Ag nanoparticle ink based on glycol ethers was used to print the electrodes. To obtain dielectric ink, a copolymer powder of poly(methyl methacrylate-co-benzoylphenyl methacrylate) containing crosslinkable side groups was dissolved in anisole. Various layouts were designed to support multiple electronic applications. Scanning electron microscopy and atomic force microscopy were used to investigate the all-printed capacitor layers formed using the proposed process. Additionally, the printed capacitors were electrically characterized under direct current and alternating current. The measured electrical properties of the printed capacitors were consistent with the theoretical results.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-11
...Recent EPA gas audit results indicate that some gas cylinders used to calibrate continuous emission monitoring systems on stationary sources do not meet EPA's performance specification. Reviews of stack test reports in recent years indicate that some stack testers do not properly follow EPA test methods or do not correctly calculate test method results. Therefore, EPA is proposing to amend its Protocol Gas Verification Program (PGVP) and the minimum competency requirements for air emission testing (formerly air emission testing body requirements) to improve the accuracy of emissions data. EPA is also proposing to amend other sections of the Acid Rain Program continuous emission monitoring system regulations by adding and clarifying certain recordkeeping and reporting requirements, removing the provisions pertaining to mercury monitoring and reporting, removing certain requirements associated with a class-approved alternative monitoring system, disallowing the use of a particular quality assurance option in EPA Reference Method 7E, adding an incorporation by reference that was inadvertently left out of the January 24, 2008 final rule, and clarifying the language and applicability of certain provisions.
Accelerating the pace of progress.
Chinery-hesse, M
1995-01-01
During the past 20 years, the proportion of women in paid employment has increased significantly. Yet women still do not have equal opportunity or receive equal treatment in the workplace. Under these conditions, society loses because it does not completely utilize all its human resources toward sustainable development. All levels of preparation for the Fourth World Conference on Women, scheduled for September 1995 in Beijing, have allowed participants to review the current social status of women. Globalization of the economy, technological transformation, and restructuring of the labor market pose difficult problems and emerging challenges for women: feminization of poverty, increasing instability of women's work, continued inequality in the sharing of family responsibilities, and inadequacy of social infrastructure to allow women both to work and to attend to their family's needs. Working women's rights continue to be neglected. The International Labor Organization's (ILO) 75 years of experience suggest that a comprehensive integrated approach and participation of all relevant actors are needed to address gender inequality in the workplace. ILO has proposed such a strategy.
Heimann, David C.; Krempa, Heather M.
2011-01-01
The effects of proposed impoundments and resulting streamflow regulation on riparian wetlands in the Marmaton River Basin, Missouri, USA were determined using measurements and numerical simulations of wetland water budgets. Calibrated and validated Soil-Plant-Air-Water (SPAW) models were used to simulate daily water depths of four riparian wetlands for Current (model scenario of existing impoundments) and Proposed (model scenario of existing and proposed impoundments) impoundment conditions. The simulated frequency of flooding decreased 19–65% at the wetlands following the additions of proposed impoundments. The reduced flooding resulted in decreases in wetland water depths at all sites during the 10 simulated growing seasons under Proposed conditions with an average duration of continuous water-depth declines of 289 days at the upstream (most regulated) site. Downstream wetlands within the zone of least regulation had an average duration of water level decreases of about 20 days. Decreased water levels under Proposed conditions resulted in a range of 65–365 additional dry days at the study wetlands during the simulated 10-year period of Proposed conditions. The areas of the four wetlands meeting the hydrologic criteria of a formal jurisdictional wetland definition decreased ranging from zero to 31% under Proposed impoundment conditions.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL... deciding a provider's contest of proposed penalties and assessments. (a) Documentary material and written...
Multivariate Cryptography Based on Clipped Hopfield Neural Network.
Wang, Jia; Cheng, Lee-Ming; Su, Tong
2018-02-01
Designing secure and efficient multivariate public key cryptosystems [multivariate cryptography (MVC)] to strengthen the security of RSA and ECC in conventional and quantum computational environment continues to be a challenging research in recent years. In this paper, we will describe multivariate public key cryptosystems based on extended Clipped Hopfield Neural Network (CHNN) and implement it using the MVC (CHNN-MVC) framework operated in space. The Diffie-Hellman key exchange algorithm is extended into the matrix field, which illustrates the feasibility of its new applications in both classic and postquantum cryptography. The efficiency and security of our proposed new public key cryptosystem CHNN-MVC are simulated and found to be NP-hard. The proposed algorithm will strengthen multivariate public key cryptosystems and allows hardware realization practicality.
Postoperative hypoxemia due to fat embolism
Bhalla, Tarun; Sawardekar, Amod; Klingele, Kevin; Tobias, Joseph D.
2011-01-01
Although the reported incidence of fat embolism syndrome (FES) is low (approximately 1%), it is likely that microscopic fat emboli are showered during manipulation of long bone fractures. Even though there continues to be debate regarding the etiology and proposed mechanism responsible for FES, significant systemic manifestations may occur. Treatment is generally symptomatic based on the clinical presentations. We report a 10-year-old girl who developed hypoxemia following treatment of a displaced Salter-Harris type II fracture of the distal tibia. The subsequent evaluation and hospital course pointed to fat embolism as the most likely etiology for the hypoxemia. We discuss the etiology for FES, review the proposed pathophysiological mechanisms responsible for its clinical manifestations, present currently accepted diagnostic criteria, and discuss its treatment. PMID:21957420
Hybrid Active-Passive Systems for Control of Aircraft Interior Noise
NASA Technical Reports Server (NTRS)
Fuller, Chris R.; Palumbo, Dan (Technical Monitor)
2002-01-01
It was proposed to continue with development and application in the two active-passive areas of Active Tuned Vibration Absorbers (ATVA) and smart foam applied to the reduction of interior noise in aircraft. In general the work was focused on making both techniques more efficient, practical and robust thus increasing their application potential. The work was also concerned with demonstrating the potential of these two technologies under realistic implementations as well as understanding the fundamental physics of the systems. The proposed work consisted of a three-year program and was tightly coordinated with related work being carried out in the Structural Acoustics Branch at NASA LaRC. The work was supervised and coordinated through all phases by Prof Chris Fuller of Va Tech.
Mild traumatic brain injury literature review and proposed changes to classification.
Krainin, Benjamin M; Forsten, Robert D; Kotwal, Russ S; Lutz, Robert H; Guskiewicz, Kevin M
2011-01-01
Mild traumatic brain injury (mTBI) reportedly occurs in 8-22% of U.S. servicemembers who conduct combat operations in Afghanistan and Iraq. The current definition for mTBI found in the medical literature, to include the Department of Defense (DoD) and Veterans Administration (VA) clinical practice guidelines is limited by the parameters of loss of consciousness, altered consciousness, or post-traumatic amnesia, and does not account for other constellations of potential symptoms. Although mTBI symptoms typically resolve within seven days, some servicemembers experience symptoms that continue for weeks, months, or years following an injury. Mild TBI is one of few disorders in medicine where a benign and misleading diagnostic classification is bestowed on patients at the time of injury, yet still can be associated with lifelong complications. This article comprehensively reviews the clinical literature over the past 20 years and proposes a new classification for TBI that addresses acute, sub-acute, and chronic phases, and includes neurocognitive, somatic, and psychological symptom presentation. 2011.
Novel optoacoustic system for noninvasive continuous monitoring of cerebral venous blood oxygenation
NASA Astrophysics Data System (ADS)
Petrov, Yuriy; Petrov, Irene Y.; Prough, Donald S.; Esenaliev, Rinat O.
2012-02-01
Traumatic brain injury (TBI) and spinal cord injury are a major cause of death for individuals under 50 years of age. In the USA alone, 150,000 patients per year suffer moderate or severe TBI. Moreover, TBI is a major cause of combatrelated death. Monitoring of cerebral venous blood oxygenation is critically important for management of TBI patients because cerebral venous blood oxygenation below 50% results in death or severe neurologic complications. At present, there is no technique for noninvasive, accurate monitoring of this clinically important variable. We proposed to use optoacoustic technique for noninvasive monitoring of cerebral venous blood oxygenation by probing cerebral veins such as the superior sagittal sinus (SSS) and validated it in animal studies. In this work, we developed a novel, medical grade optoacoustic system for continuous, real-time cerebral venous blood oxygenation monitoring and tested it in human subjects at normal conditions and during hyperventilation to simulate changes that may occur in patients with TBI. We designed and built a highly-sensitive optoacoustic probe for SSS signal detection. Continuous measurements were performed in the near infrared spectral range and the SSS oxygenation absolute values were automatically calculated in real time using a special algorithm developed by our group. Continuous measurements performed at normal conditions and during hyperventilation demonstrated that hyperventilation resulted in approximately 12% decrease of cerebral venous blood oxygenation.
5 CFR 890.1022 - Contesting proposed permissive debarments.
Code of Federal Regulations, 2014 CFR
2014-01-01
.... 890.1022 Section 890.1022 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1022 Contesting proposed permissive debarments...
5 CFR 890.1022 - Contesting proposed permissive debarments.
Code of Federal Regulations, 2013 CFR
2013-01-01
.... 890.1022 Section 890.1022 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1022 Contesting proposed permissive debarments...
NASA Astrophysics Data System (ADS)
Li, Changgang; Sun, Yanli; Yu, Yawei
2017-05-01
Under frequency load shedding (UFLS) is an important measure to tackle with frequency drop caused by load-generation imbalance. In existing schemes, loads are shed by relays in a discontinuous way, which is the major reason leading to under-shedding and over-shedding problems. With the application of power electronics technology, some loads can be controlled continuously, and it is possible to improve the UFSL with continuous loads. This paper proposes an UFLS scheme by shedding loads continuously. The load shedding amount is proportional to frequency deviation before frequency reaches its minimum during transient process. The feasibility of the proposed scheme is analysed with analytical system frequency response model. The impacts of governor droop, system inertia, and frequency threshold on the performance of the proposed UFLS scheme are discussed. Cases are demonstrated to validate the proposed scheme by comparing it with conventional UFLS schemes.
2016-03-01
contributions not begin until completion of 4 YOS , in order to reduce the incentive to accumulate savings and separate [2]. Under the commission’s plan...3 who reach 12 YOS and are willing and able to incur an additional 4 -year obligation. DOD’s proposal, however, recommends that the...on returns on federal employees’ TSP accounts. 4 . On completing their 12th YOS , enlisted personnel will receive a continuation bonus that is equal
Fabric-based Pressure Sensor Array for Decubitus Ulcer Monitoring
Chung, Philip; Rowe, Allison; Etemadi, Mozziyar; Lee, Hanmin; Roy, Shuvo
2015-01-01
Decubitus ulcers occur in an estimated 2.5 million Americans each year at an annual cost of $11 billion to the U.S. health system. Current screening and prevention techniques for assessing risk for decubitus ulcer formation and repositioning patients every 1–2 hours are labor-intensive and can be subjective. We propose use of a Bluetooth-enabled fabric-based pressure sensor array as a simple tool to objectively assess and continuously monitor decubitus ulcer risk. PMID:24111232
Synthesis of thermally stable polypyrazoles, polypyrimidines and other heteroaromatic polymers
NASA Technical Reports Server (NTRS)
Bass, R. G.
1986-01-01
As part of a continuing effort to prepare high performance-high temperature polymers for functional and structural applications, the reactions of aromatic dipropynones with aromatic dihydrazine, aromatic dithiols, and aromatic diamidines to provide polypyrazoles, polyenonesulfides, and polypyrimidines respectively were investigated. During the past year, it was demonstrated that polypyrazoles and polyenonesulfides may be prepared by the proposed procedures. However, the preparation of polypyrimidines was not achieved. The preparation and characterization of some polypyrazolones by reaction or aromatic dihydrazines with an activated diacetylenic diester was achieved.
1989-09-01
motivation and employee retention has been a subject of research for years. One of the most popular theories was proposed by Abraham Maslow in the 1940...free from threats to continued existence. 3. Belongingness Needs. The desire to be accepted by ones peers, to have friendships, and to be loved...Frederick Herzberg in the way employees are motivated. Herzberg divided the factors which were intrinsic to the job itself into two categories. The
From Mild to WildLV14378 Fluctuations in Crystal Plasticity
NASA Astrophysics Data System (ADS)
Weiss, J.; Rhouma, W. Ben; Richeton, T.; Dechanel, S.; Louchet, F.; Truskinovsky, L.
2015-03-01
Macroscopic crystal plasticity is classically viewed as an outcome of uncorrelated dislocation motions producing Gaussian fluctuations. An apparently conflicting picture emerged in recent years emphasizing highly correlated dislocation dynamics characterized by power-law distributed fluctuations. We use acoustic emission measurements in crystals with different symmetries to show that intermittent and continuous visions of plastic flow are not incompatible. We demonstrate the existence of crossover regimes where strongly intermittent events coexist with a Gaussian quasiequilibrium background and propose a simple theoretical framework compatible with these observations.
A national medical register: balancing public transparency and professional privacy.
Healy, Judith M; Maffi, Costanza L; Dugdale, Paul
2008-02-18
The first aim of a medical registration scheme should be to protect patients. Medical registration boards currently offer variable information to the public on doctors' registration status. Current reform proposals for a national registration scheme should include free public access to professional profiles of registered medical practitioners. Practitioner profiles should include: practitioner's full name and practice address; type of qualifications; year first registered, and duration and type of registration; any conditions on registration and practice; any disciplinary action taken; and participation in continuing professional education.
A population policy for Zimbabwe Rhodesia.
Hanks, J
1979-01-01
The author offers suggestions for the implementation of a population policy in Zimbabwe, with the aim of substantially reducing that country's birth rate within the next 10 years. He briefly examines the consequences of continued population growth and suggests steps to be taken by the government in preparation for the introduction of a population policy. Courses of action for policy implementation are proposed, including organization of public information programs, provision of family planning services, introduction of incentive programs, and promotion of reproductive research
Status and Needs Research for On-line Monitoring of VOCs Emissions from Stationary Sources
NASA Astrophysics Data System (ADS)
Zhou, Gang; Wang, Qiang; Zhong, Qi; Zhao, Jinbao; Yang, Kai
2018-01-01
Based on atmospheric volatile organic compounds (VOCs) pollution control requirements during the twelfth-five year plan and the current status of monitoring and management at home and abroad, instrumental architecture and technical characteristics of continuous emission monitoring systems (CEMS) for VOCs emission from stationary sources are investigated and researched. Technological development needs of VOCs emission on-line monitoring techniques for stationary sources in china are proposed from the system sampling pretreatment technology and analytical measurement techniques.
Director's Discretionary Research and Development Program: Annual Report, Fiscal Year 2005
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
2005-12-01
The Director's Discretionary Research and Development (DDRD) program is designed to encourage technical innovation and build new research and development capabilities at the National Renewable Energy Laboratory (NREL). Technical innovation is critical to the long-term viability of NREL (also referred to as the Laboratory) and to the success of the U.S. Department of Energy (DOE). The strategic value of DDRD is being continuously enhanced by expanding the opportunities to propose and pursue innovative ideas for building new and enhanced capabilities.
Analysis and design of continuous class-E power amplifier at sub-nominal condition
NASA Astrophysics Data System (ADS)
Chen, Peng; Yang, Kai; Zhang, Tianliang
2017-12-01
The continuous class-E power amplifier at sub-nominal condition is proposed in this paper. The class-E power amplifier at continuous mode means it can be high efficient on a series matching networks while at sub-nominal condition means it only requires the zero-voltage-switching condition. Comparing with the classical class-E power amplifier, the proposed design method releases two additional design freedoms, which increase the class-E power amplifier's design flexibility. Also, the proposed continuous class-E power amplifier at sub-nominal condition can perform high efficiency over a broad bandwidth. The performance study of the continuous class-E power amplifier at sub-nominal condition is derived and the design procedure is summarised. The normalised switch voltage and current waveforms are investigated. Furthermore, the influences of different sub-nominal conditions on the power losses of the switch-on resistor and the output power capability are also discussed. A broadband continuous class-E power amplifier based on a Gallium Nitride (GaN) transistor is designed and testified to verify the proposed design methodology. The measurement results show, it can deliver 10-15 W output power with 64-73% power-added efficiency over 1.4-2.8 GHz.
Breastfeeding indicators trends in Brazil for three decades
Boccolini, Cristiano Siqueira; Boccolini, Patricia de Moraes Mello; Monteiro, Fernanda Ramos; Venâncio, Sonia Isoyama; Giugliani, Elsa Regina Justo
2017-01-01
ABSTRACT OBJECTIVE Update breastfeeding indicators trend in Brazil for the last three decades, incorporating more up-to-date information from the National Health Survey. METHODS We used secondary data from national surveys with information on breastfeeding (1986, 1996, 2006, and 2013) to construct the time series of prevalence for the following indicators: exclusive breastfeeding in children under six months of age (EBF6m), breastfeeding in toddlers under 2 years of age (BF), continued breastfeeding at one year of age (BF1year), and continued breastfeeding at two years of age (BF2years). RESULTS The prevalence of EBF6m, BF, and BF1year increased until 2006 (rising from 4.7%, 37.4%, and 25.5% in 1986 to 37.1%, 56.3%, and 47.2% in 2006, respectively). For these three indicators, there was relative stabilization between 2006 and 2013 (36.6%, 52.1%, and 45.4%, respectively). The BF2years indicator had a distinct behavior – relatively stable prevalence, around 25% between 1986 and 2006, and a subsequent increase, reaching 31.8% in 2013. CONCLUSIONS The time series of breastfeeding indicators in Brazil shows an upward trend until 2006, stabilizing from that date onwards on three of the four indicators evaluated. This result, which can be considered as a warning sign, requires evaluation and revision of policies and programs to promote, protect and support breastfeeding, strengthening existing ones and proposing new strategies so that the prevalence of breastfeeding indicators returns to an upwards trend. PMID:29166437
76 FR 10900 - Agency Information Collection Activities: Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-28
... activity is designed to raise awareness of and utility of comparative effectiveness research by providing... proposed information collection project: ``Comparative Effectiveness Research--Continuing Education.'' In... Comparative Effectiveness Research--Continuing Education Previous dissemination efforts in health care...
29 CFR 1990.141 - Advance notice of proposed rulemaking.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 1990.141 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) IDENTIFICATION, CLASSIFICATION, AND REGULATION OF POTENTIAL OCCUPATIONAL CARCINOGENS Regulation of Potential Occupational Carcinogens § 1990.141 Advance notice of proposed rulemaking...
29 CFR 1990.141 - Advance notice of proposed rulemaking.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 1990.141 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) IDENTIFICATION, CLASSIFICATION, AND REGULATION OF POTENTIAL OCCUPATIONAL CARCINOGENS Regulation of Potential Occupational Carcinogens § 1990.141 Advance notice of proposed rulemaking...
5 CFR 890.1009 - Contesting proposed mandatory debarments.
Code of Federal Regulations, 2010 CFR
2010-01-01
.... 890.1009 Section 890.1009 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Mandatory Debarments § 890.1009 Contesting proposed mandatory debarments. (a...
5 CFR 890.1009 - Contesting proposed mandatory debarments.
Code of Federal Regulations, 2013 CFR
2013-01-01
.... 890.1009 Section 890.1009 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Mandatory Debarments § 890.1009 Contesting proposed mandatory debarments. (a...
5 CFR 890.1009 - Contesting proposed mandatory debarments.
Code of Federal Regulations, 2014 CFR
2014-01-01
.... 890.1009 Section 890.1009 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Mandatory Debarments § 890.1009 Contesting proposed mandatory debarments. (a...
5 CFR 890.1014 - Notice of proposed permissive debarment.
Code of Federal Regulations, 2010 CFR
2010-01-01
.... 890.1014 Section 890.1014 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1014 Notice of proposed permissive debarment...
5 CFR 890.1014 - Notice of proposed permissive debarment.
Code of Federal Regulations, 2013 CFR
2013-01-01
.... 890.1014 Section 890.1014 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1014 Notice of proposed permissive debarment...
5 CFR 890.1014 - Notice of proposed permissive debarment.
Code of Federal Regulations, 2012 CFR
2012-01-01
.... 890.1014 Section 890.1014 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1014 Notice of proposed permissive debarment...
5 CFR 890.1014 - Notice of proposed permissive debarment.
Code of Federal Regulations, 2014 CFR
2014-01-01
.... 890.1014 Section 890.1014 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1014 Notice of proposed permissive debarment...
5 CFR 890.1014 - Notice of proposed permissive debarment.
Code of Federal Regulations, 2011 CFR
2011-01-01
.... 890.1014 Section 890.1014 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1014 Notice of proposed permissive debarment...
Transportation Electrification Education Partnership for Green Jobs and Sustainable Mobility
DOE Office of Scientific and Technical Information (OSTI.GOV)
Peng, Huei; Mi, Chris; Gover, James
This collaborative educational project between the University of Michigan—Ann Arbor, University of Michigan—Dearborn and the Kettering University successfully executed almost all the elements we proposed to do. In the original proposal, we proposed to develop four graduate courses, six undergraduate courses, four professional short courses, a K-12 electric vehicle education kit, a Saturday morning seminar series, and a set of consumer education material to support the advancement of transportation electrification. The first four deliverables were all successfully developed and offered. When we held the kick-off meeting in NETL in Morgantown back in early 2010 with all the ten ARRA educationmore » teams, however, it quickly became clear that among the ten ARRA education grantee teams, our proposed “consume education” activities are not better or with the potential to create bigger impact than some of activities proposed in other teams. For example, the Odyssey 2010 event held by the West Virginia University team had planned and successfully reached to more than 230,000 attendees, which is way more than what our proposed 100k event could ever reach. It was under the suggestion of Joseph Quaranta, the ARRA education Program Director at that time, that we should coordinate and eliminate redundancy. The resources should then be focused on activities that have less overlap. Therefore, the originally proposed activities: Saturday morning seminar series, and a set of consumer education material were dropped from our scope. We expanded the scope of our “education kit” activity to include some educational materials, mainly in the form of videos. The target audience also changed from general public to K-12 students. The majority of the project cost (~70%) goes toward the establishment of three undergraduate laboratories, which provides critically needed hands-on learning experience for next-generation green mobility engineers. We are very proud that the ARRA money, which was distributed as part of the economy stimulus package back in 2009, was used to invest in laboratories which are already impacting the learning experience of our undergraduate and graduate students, and will continue to do so in the coming decades. The offering and enrollments of the ten undergraduate and graduate courses developed under the support of this educational grant is summarized in the table below. The grant was finalized in September 2009, and four new courses were developed and offered soon after in Winter 2010. The other six courses were developed thereafter. The total number of students who took these new courses over the duration of this grant is just over 1,000. In the first 2 years, under the DOE funding, the courses are offered more regularly. After that, the courses were considered together with other existing courses in the planning of teaching schedule and may not be offered each year. Almost all of the 10 courses have healthy enrollments and we do expect them to be offered continuously in the future. The graduate courses perhaps will be offered every 2-3 years, and the undergraduate courses most likely on a yearly basis.« less
High Temperature Boost (HTB) Power Processing Unit (PPU) Formulation Study
NASA Technical Reports Server (NTRS)
Chen, Yuan; Bradley, Arthur T.; Iannello, Christopher J.; Carr, Gregory A.; Mohammad, Mojarradi M.; Hunter, Don J.; DelCastillo, Linda; Stell, Christopher B.
2013-01-01
This technical memorandum is to summarize the Formulation Study conducted during fiscal year 2012 on the High Temperature Boost (HTB) Power Processing Unit (PPU). The effort is authorized and supported by the Game Changing Technology Division, NASA Office of the Chief Technologist. NASA center participation during the formulation includes LaRC, KSC and JPL. The Formulation Study continues into fiscal year 2013. The formulation study has focused on the power processing unit. The team has proposed a modular, power scalable, and new technology enabled High Temperature Boost (HTB) PPU, which has 5-10X improvement in PPU specific power/mass and over 30% in-space solar electric system mass saving.
76 FR 30364 - Agency Information Collection Activities: Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-25
... professionals, and other clinicians. This activity is designed to raise awareness of and utility of comparative... proposed information collection project: ``Comparative Effectiveness Research-Continuing Education.'' In... Comparative Effectiveness Research-Continuing Education Previous dissemination efforts in health care research...
Conventional armed forces in Europe: Technology scenario development
DOE Office of Scientific and Technical Information (OSTI.GOV)
Houser, G.M.
1990-07-01
In January 1986, the Soviet Union's Mikhail Gorbachev proposed elimination of all nuclear weapons by the year 2000. In April of that year, Mr. Gorbachev proposed substantial reductions of conventional weapons in Europe, from the Atlantic Ocean to the Ural Mountains, including reductions in operational-tactical nuclear weapons. In May 1986, the North Atlantic Treaty Organization (NATO) responded with the Brussels Declaration on Conventional Arms Control,'' which indicated readiness to open East/West discussions on establishing a mandate for negotiating conventional arms control throughout Europe. The Group of 23,'' which met in Vienna beginning in February 1987, concluded the meeting in Januarymore » 1989 with a mandate for the Conventional Armed Forced in Europe (CFE) negotiations. On 6 March 1989, CFE talks began, and these talks have continued through six rounds (as of April 1990). Although US President George Bush, on 30 May 1989, called for agreement within six months to a year, and the Malta meeting of December 1989 called for completion of a CFE agreement by the end of 1990, much remains to be negotiated. This report provides three types of information. First, treaty provisions brought to the table by both sides are compared. Second, on the basis of these provisions, problem areas for each of the provision elements are postulated and possible scenarios for resolving these problem areas are developed. Third, the scenarios are used as requirements for tasks assigned program elements for possible US implementation of a CFE treaty. As progress is achieved during the negotiations, this report could be updated, as necessary, in each of the areas to provide a continuing systematic basis for program implementation and technology development. 8 refs.« less
NASA Institute for Advanced Concepts
NASA Technical Reports Server (NTRS)
Cassanova, Robert A.
1999-01-01
The purpose of NASA Institute for Advanced Concepts (NIAC) is to provide an independent, open forum for the external analysis and definition of space and aeronautics advanced concepts to complement the advanced concepts activities conducted within the NASA Enterprises. The NIAC will issue Calls for Proposals during each year of operation and will select revolutionary advanced concepts for grant or contract awards through a peer review process. Final selection of awards will be with the concurrence of NASA's Chief Technologist. The operation of the NIAC is reviewed biannually by the NIAC Science, Exploration and Technology Council (NSETC) whose members are drawn from the senior levels of industry and universities. The process of defining the technical scope of the initial Call for Proposals was begun with the NIAC "Grand Challenges" workshop conducted on May 21-22, 1998 in Columbia, Maryland. These "Grand Challenges" resulting from this workshop became the essence of the technical scope for the first Phase I Call for Proposals which was released on June 19, 1998 with a due date of July 31, 1998. The first Phase I Call for Proposals attracted 119 proposals. After a thorough peer review, prioritization by NIAC and technical concurrence by NASA, sixteen subgrants were awarded. The second Phase I Call for Proposals was released on November 23, 1998 with a due date of January 31, 1999. Sixty-three (63) proposals were received in response to this Call. On December 2-3, 1998, the NSETC met to review the progress and future plans of the NIAC. The next NSETC meeting is scheduled for August 5-6, 1999. The first Phase II Call for Proposals was released to the current Phase I grantees on February 3,1999 with a due date of May 31, 1999. Plans for the second year of the contract include a continuation of the sequence of Phase I and Phase II Calls for Proposals and hosting the first NIAC Annual Meeting and USRA/NIAC Technical Symposium in NASA HQ.
Doubly Robust Additive Hazards Models to Estimate Effects of a Continuous Exposure on Survival.
Wang, Yan; Lee, Mihye; Liu, Pengfei; Shi, Liuhua; Yu, Zhi; Abu Awad, Yara; Zanobetti, Antonella; Schwartz, Joel D
2017-11-01
The effect of an exposure on survival can be biased when the regression model is misspecified. Hazard difference is easier to use in risk assessment than hazard ratio and has a clearer interpretation in the assessment of effect modifications. We proposed two doubly robust additive hazards models to estimate the causal hazard difference of a continuous exposure on survival. The first model is an inverse probability-weighted additive hazards regression. The second model is an extension of the doubly robust estimator for binary exposures by categorizing the continuous exposure. We compared these with the marginal structural model and outcome regression with correct and incorrect model specifications using simulations. We applied doubly robust additive hazard models to the estimation of hazard difference of long-term exposure to PM2.5 (particulate matter with an aerodynamic diameter less than or equal to 2.5 microns) on survival using a large cohort of 13 million older adults residing in seven states of the Southeastern United States. We showed that the proposed approaches are doubly robust. We found that each 1 μg m increase in annual PM2.5 exposure was associated with a causal hazard difference in mortality of 8.0 × 10 (95% confidence interval 7.4 × 10, 8.7 × 10), which was modified by age, medical history, socioeconomic status, and urbanicity. The overall hazard difference translates to approximately 5.5 (5.1, 6.0) thousand deaths per year in the study population. The proposed approaches improve the robustness of the additive hazards model and produce a novel additive causal estimate of PM2.5 on survival and several additive effect modifications, including social inequality.
A Proposed Robotic Astronomy Mission to the Lunar South Polar Regions
NASA Technical Reports Server (NTRS)
Lowman, Paul D., Jr.
2003-01-01
This paper outlines a possible mission to emplace a robotic infrared / submillimeter wave interferometer array near the lunar south pole. This region has now been investigated by the Clementine and Lunar Prospector missions, and by Earth-based radar, and its topography and thermal environment are fairly well-known. The area would be exceptionally suitable for infrared / submillimeter astronomy because of the continually low temperatures, approaching that of liquid nitrogen (77K) in some places. A submillimeter spaceborne interferometer mission, Submillimeter Probe of the Evolution of the Cosmic Structure (SPECS) has been proposed by John Mather and others, covering the 40 - 500 micron region with 3 formation flying telescopes. The present paper proposes a lunar adaptation of the SPECS concept, LSPECS. This adaptation would involve landing 4 telescopes on the area north of Shackleton crater at zero degrees longitude. This is in nearly year round darkness but is continually radar visible from Earth. The landed payload of LSPECS would include a telerobotic rover, 4 three meter submm telescopes, a solar power array to be emplaced on the continually sunlit north rim of Shackleton crater, and an S-band antenna for data relay to Earth. Passive cooling without the use of expendable cryogenics. might be possible, trading long exposure time for instrument temperatures above that of liquid helium. The LSPECS would permit long-term study of an extremely wide range of cosmic and solar system phenomena in the southern celestial hemisphere. For complete sky coverage, a similar installation near the north pole would be required. The LSPECS site would also be suitable other types of observation, such as optical interferometry or centimeter wavelength radio astronomy. The lunar south pole is also of great interest because of its extensive ice deposits, which may represent cometary infall with pre-biotic compounds.
47 CFR 43.43 - Reports of proposed changes in depreciation rates.
Code of Federal Regulations, 2010 CFR
2010-10-01
... rates. 43.43 Section 43.43 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) REPORTS OF COMMUNICATION COMMON CARRIERS AND CERTAIN AFFILIATES § 43.43 Reports of proposed changes in depreciation rates. (a) Each communication common carrier with annual...
5 CFR 890.1013 - Deciding whether to propose a permissive debarment.
Code of Federal Regulations, 2013 CFR
2013-01-01
... debarment. 890.1013 Section 890.1013 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1013 Deciding whether to propose a...
5 CFR 890.1013 - Deciding whether to propose a permissive debarment.
Code of Federal Regulations, 2014 CFR
2014-01-01
... debarment. 890.1013 Section 890.1013 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1013 Deciding whether to propose a...
5 CFR 890.1013 - Deciding whether to propose a permissive debarment.
Code of Federal Regulations, 2010 CFR
2010-01-01
... debarment. 890.1013 Section 890.1013 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1013 Deciding whether to propose a...
Modeling and Experiment of Melt Impregnation of Continuous Fiber-reinforced Thermoplastic with Pins
NASA Astrophysics Data System (ADS)
Yang, Jian-Jun; Xin, Chun-Ling; Tang, Ke; Zhang, Zhi-Cheng; Yan, Bao-Rui; Ren, Feng; He, Ya-Dong
2016-05-01
Melt impregnation is a crucial method for continuous fiber-reinforced thermoplastic. It was developed several years ago for thermosetting plastic, but it is very popular now in the thermoplastic matrices, with a much higher viscosity. In this paper, we propose a mathematic model based on Darcy's law, which combined with processing parameters and material physical parameters. Then we use this model to predict the influence of processing parameters on the degree of impregnation of the prepreg, and the trend of prediction is consistent with the experimental results. Therefore, the exhaustive numerical study enables to define the optimal processing conditions for a perfect impregnation. The results are shown to be effective tools for finding optimal pulling speed, pin number and pressure for a given fluid/fibers pair.
Why older nurses leave the workforce and the implications of them staying.
Duffield, Christine; Graham, Elizabeth; Donoghue, Judith; Griffiths, Rhonda; Bichel-Findlay, Jen; Dimitrelis, Sofia
2015-03-01
To identify factors that motivate older nurses to leave the workforce. As many older nurses are now reaching retirement age and will be eligible for government-funded pensions, governments are concerned about the impending financial burden. To prepare for this scenario, many are looking at increasing the age of retirement to 67 or 70 years. Little is known about how this will affect the continuing employment of older nurses and the consequences for employers and the nurses themselves if they remain longer in the workforce. Prospective randomised quantitative survey study. The Mature Age Workers Questionnaire, Job Descriptive Index and Job in General Scale were used to measure job satisfaction, intention to retire and factors encouraging retirement in registered nurses aged 45 years and over (n = 352) in Australia (July-August 2007). There were 319 respondents. The mean age proposed for leaving the workforce was 61·7 years. Key motivators were: financial considerations (40·1%), primarily financial security; nurse health (17·4%) and retirement age of partner (13·3%). Older nurses are leaving the workforce prior to retirement or pension age, primarily for financial, social and health reasons, taking with them significant experience and knowledge. As financial considerations are important in older nurses decisions to continue to work, increasing the age of retirement may retain them. However, consideration will need to be given to ensure that they continue to experience job satisfaction and are physically and mentally able to undertake demanding work. Increasing retirement age may retain older nurses in the workforce, however, the impact on the health of older nurses is not known, nor is the impact for employers of older nurses continuing to work known. Employers must facilitate workplace changes to accommodate older nurses. © 2014 John Wiley & Sons Ltd.
SPIRITS: SPitzer InfraRed Intensive Transients Survey
NASA Astrophysics Data System (ADS)
Kasliwal, Mansi; Lau, Ryan; Cao, Yi; Masci, Frank; Helou, George; Williams, Robert; Bally, John; Bond, Howard; Whitelock, Patricia; Cody, Ann Marie; Gehrz, Robert; Jencson, Jacob; Tinyanont, Samaporn; Smith, Nathan; Surace, Jason; Armus, Lee; Cantiello, Matteo; Langer, Norbert; Levesque, Emily; Mohamed, Shazrene; Ofek, Eran; Parthasarathy, Mudumba; van Dyk, Schuyler; Boyer, Martha; Phillips, Mark; Hsiao, Eric; Morrell, Nidia; Perley, Dan; Gonzalez, Consuelo; Contreras, Carlos; Jones, Olivia; Ressler, Michael; Adams, Scott; Moore, Anna; Cook, David; Fox, Ori; Johansson, Joel; Khan, Rubab; Monson, Andy
2016-08-01
Spitzer is pioneering a systematic exploration of the dynamic infrared sky. Our SPitzer InfraRed Intensive Transients Survey (SPIRITS) has already discovered 147 explosive transients and 1948 eruptive variables. Of these 147 infrared transients, 35 are so red that they are devoid of optical counterparts and we call them SPRITEs (eSPecially Red Intermediate-luminosity Transient Events). The nature of SPRITEs is unknown and progress on deciphering the explosion physics depends on mid-IR spectroscopy. Multiple physical origins have been proposed including stellar merger, birth of a massive binary, electron capture supernova and stellar black-hole formation. Hence, we propose a modest continuation of SPIRITS, focusing on discovering and monitoring SPRITEs, in preparation for follow-up with the James Webb Space Telescope (JWST). As the SPRITEs evolve and cool, the bulk of the emission shifts to longer wavelengths. MIRI aboard JWST will be the only available platform in the near future capable of characterizing SPRITEs out to 28um. Specifically, the low resolution spectrometer would determine dust mass, grain chemistry, ice abundance and energetics to disentangle the proposed origins. The re-focused SPIRITS program consists of continued Spitzer monitoring of only those 104 luminous galaxies that are known SPRITE hosts or are most likely to host new SPRITEa. Scaling from the SPIRITS discovery rate, we estimate finding 22 new SPRITEs and 6 new supernovae over the next two years. The SPIRITS team remains committed to extensive ground-based follow-up. The Spitzer observations proposed here are essential for determining the final fates of active SPRITEs as well as bridging the time lag between the current SPIRITS survey and JWST launch.
López-Torres, M; Pérez-Campo, R; Fernandez, A; Barba, C; Barja de Quiroga, G
1993-02-01
Brain catalase was continuously depleted throughout the life span starting with a large population of initially young and old frogs. Free radical-related parameters were measured in the brain tissue once per year after 2.5, 14.5, and 26.5 months of experimentation. Brain lipofuscin accumulation was observed after 14.5 and 26.5 months, and survival was continuously followed during 33 months. The age of the animal did not decrease endogenous antioxidants nor increase tissue peroxidation either in cross-sectional or longitudinal comparisons. Continuous catalase depletion similarly affected young and old animals, inducing glutathione reductase, tending to decrease oxidized glutathione/reduced glutathione (GSSG/GSH) ratio, decreasing lipofuscin accumulation in the brain, and increasing survival from 46% to 91% after 14.5 months. At 26.5 months of experimentation the loss of the glutathione reductase induction in catalase-depleted animals was accompanied by the presence of higher lipofuscin deposits than in controls and was followed by a great increase in mortality rate. Even though the maximal life span (7 years) was the same in the control and treated animals which were already old (4.2 years) at the beginning of the experiment, the treated animals showed a strong reduction in the rates of early death. It is proposed that the maintenance of a high antioxidant/prooxidant balance in the vertebrate brain greatly increases the probability of the individual to reach the final segments of its species-specific life span.
NATIONAL SYNCHROTRON LIGHT SOURCE ACTIVITY REPORT 2004
DOE Office of Scientific and Technical Information (OSTI.GOV)
MILLER,L.; EDITOR)
2005-05-01
The NSLS remains a viable and productive facility, as can be seen by the rich and diverse science produced in 2004. In one of these exciting research projects published in Nature, researchers detected a rare 'hole crystal' in a cuprate superconductor, which may provide insight into high-temperature superconductivity. In another Nature publication, the crystal structure of a segment of RNA was determined, opening a new window of knowledge into that crucial molecule. These are just a couple of the science highlights of 2004, and many others are displayed in the pages of this report. All told, more than 700 publicationsmore » resulted from NSLS research this year, the facility hosted 2,299 users, and the number of experiments performed rose from 1,145 in 2003 to 1,374 nuclear indications that the NSLS continues to thrive. As the NSLS accelerator complex enters its third decade of operations, it continues to perform very well. For 2004, the overall reliability of the VUV-IR ring was excellent at 99 percent. The reliability of the x-ray ring was just shy of 92 percent, primarily due to the need to replace the injection septum vacuum chamber, which developed a leak during the middle of the year. The Operations Division did a tremendous job of installing our spare chamber in minimal time, despite the complexity of the job and the inaccessibility of its location in the ring, as well as keeping downtime to a minimum throughout the rest of the year. In order to continue to meet the needs of users, several key beamline upgrades took place this year that will enrich our scientific programs, including upgrades to beamlines U12IR, X1A, X13A, and X21. We are very excited about two brand-new beamlines that were commissioned in 2004: X29 and X27A. X29 is the new mini-gap undulator beamline designed for macromolecular crystallography, and it will meet the growing demand of NSLS users who perform research in that area. The establishment of an x-ray microprobe at beamline X27A, optimized for the environmental science community, is also very important, as it will help to satisfy the large over subscription rate for this technique at the NSLS. Two other important upgrades that were initiated this past year are the replacement of the X25 wiggler with an undulator and the construction of the X9 undulator beamline for small-angle scattering, with an emphasis on nanoscience research. Another key activity that will benefit all users was the restoration of the x-ray ring lattice symmetry, which reduced the horizontal emittance and made the operational lattice more robust. Similarly, all users will benefit from the introduction of the PASS (Proposal Allocation Safety Scheduling) system this past year, which has greatly improved the process of proposal submission, review, allocation, and scheduling. This coming year we will work to add Rapid Access to the capabilities of PASS. Overall, the success of these and the many other projects that space does not permit listing is a testament to the dedication, hard work, and skill of the NSLS staff. Safety has always been an important issue at a large, complex scientific facility like the NSLS and in 2004 it received renewed attention. Safety is our highest priority and we spent a great deal of time reviewing and refining our safety practices and procedures. A new 'Safety Highlights' web page was created for safety news, and a large number of safety meetings and discussions were held. These reviews and meetings generated many ideas on how the NSLS might improve its safety practices, and we are committed to putting these in place and improving our already very good safety program. We had no lost-time accidents in 2004, which is a notable accomplishment. Our goal is to be best in class and I'm confident that by working together we can achieve that status. Several activities took place this past year to advance our proposal to replace the NSLS with a new National Synchrotron Light Source-II facility. These included a major workshop in support of the proposed facility in March, a mail review of our proposal outlinin« less
32 CFR 204.7 - Legislative proposals.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 2 2010-07-01 2010-07-01 false Legislative proposals. 204.7 Section 204.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED... provided on a substantially self-sustaining basis and thus is dependent upon adequate collections. (1) The...
32 CFR 204.7 - Legislative proposals.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 2 2011-07-01 2011-07-01 false Legislative proposals. 204.7 Section 204.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED... provided on a substantially self-sustaining basis and thus is dependent upon adequate collections. (1) The...
32 CFR 204.7 - Legislative proposals.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 2 2013-07-01 2013-07-01 false Legislative proposals. 204.7 Section 204.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED... provided on a substantially self-sustaining basis and thus is dependent upon adequate collections. (1) The...
A New Continuous-Time Equality-Constrained Optimization to Avoid Singularity.
Quan, Quan; Cai, Kai-Yuan
2016-02-01
In equality-constrained optimization, a standard regularity assumption is often associated with feasible point methods, namely, that the gradients of constraints are linearly independent. In practice, the regularity assumption may be violated. In order to avoid such a singularity, a new projection matrix is proposed based on which a feasible point method to continuous-time, equality-constrained optimization is developed. First, the equality constraint is transformed into a continuous-time dynamical system with solutions that always satisfy the equality constraint. Second, a new projection matrix without singularity is proposed to realize the transformation. An update (or say a controller) is subsequently designed to decrease the objective function along the solutions of the transformed continuous-time dynamical system. The invariance principle is then applied to analyze the behavior of the solution. Furthermore, the proposed method is modified to address cases in which solutions do not satisfy the equality constraint. Finally, the proposed optimization approach is applied to three examples to demonstrate its effectiveness.
A secure RFID-based WBAN for healthcare applications.
Ullah, Sana; Alamri, Atif
2013-10-01
A Wireless Body Area Network (WBAN) allows the seamless integration of small and intelligent invasive or non-invasive sensor nodes in, on or around a human body for continuous health monitoring. These nodes are expected to use different power-efficient protocols in order to extend the WBAN lifetime. This paper highlights the power consumption and security issues of WBAN for healthcare applications. Numerous power saving mechanisms are discussed and a secure RFID-based protocol for WBAN is proposed. The performance of the proposed protocol is analyzed and compared with that of IEEE 802.15.6-based CSMA/CA and preamble-based TDMA protocols using extensive simulations. It is shown that the proposed protocol is power-efficient and protects patients' data from adversaries. It is less vulnerable to different attacks compared to that of IEEE 802.15.6-based CSMA/CA and preamble-based TDMA protocols. For a low traffic load and a single alkaline battery of capacity 2.6 Ah, the proposed protocol could extend the WBAN lifetime, when deployed on patients in hospitals or at homes, to approximately five years.
Weather related continuity and completeness on Deep Space Ka-band links: statistics and forecasting
NASA Technical Reports Server (NTRS)
Shambayati, Shervin
2006-01-01
In this paper the concept of link 'stability' as means of measuring the continuity of the link is introduced and through it, along with the distributions of 'good' periods and 'bad' periods, the performance of the proposed Ka-band link design method using both forecasting and long-term statistics has been analyzed. The results indicate that the proposed link design method has relatively good continuity and completeness characteristics even when only long-term statistics are used and that the continuity performance further improves when forecasting is employed. .
Gill, Jan S; Gibson, Caroline; Nicol, Maggie
2010-01-01
This study compares the views of final year medical, and nursing and allied health professional (NAHP) students in relation to four governmental proposals impacting on the sale and purchase of alcohol. Against a background of political will to address alcohol abuse in Scotland and moves within the National Health Service promoting a shifting of professional roles, self-completed questionnaires were administered in spring 2009 through course websites and lectures to final year medical and NAHP students. Questionnaires were returned by 406 NAHPs and 121 medical students. Over three quarters of all students agreed with the proposed change to reduce the drink driving limit to 50 mg/100 ml blood. Less support was evident for the raising of the minimum legal purchase age for off-sales (37%), the banning of below cost price promotions of alcohol (47%) and minimum retail pricing (37%). However, there were differences between the NAHP and medical students in the case of the final two proposals; over 60% of the medical students agreed they would have a positive impact. For NAHPs, figures were 41% and 31%, respectively. Support for four key proposals outlined by the Scottish Government to address alcohol misuse varied. Only the suggestion to lower the drink driving limit received backing overall and within students in these professions. Effectiveness of proposed restrictions on the price of alcohol was less well regarded except by medical students. Evident gaps in knowledge around health guidelines, and the finding that almost half of NAHPs disagreed that they had the appropriate knowledge to advise patients about responsible drinking advice and alcohol misuse problems, suggest a need for improved undergraduate education and continued professional development with respect to public health aspects of alcohol use.
2007-09-19
This final rule will establish a system of revisit user fees applicable to health care facilities that have been cited for deficiencies during initial certification, recertification, or substantiated complaint surveys and require a revisit to confirm that corrections to previously-identified deficiencies have been remedied. Consistent with the President's long-term goal to promote quality of health care and to cut the deficit in half by fiscal year (FY) 2009, the FY 2007 Department of Health and Human Services' (HHS) budget request included both new mandatory savings proposals and a requirement that user fees be applied to health care providers that have failed to comply with Federal quality of care requirements. The "Revisit User Fees" will affect only those providers or suppliers for which a revisit is required to confirm that previously-identified failures to meet federal quality of care requirements have been remedied. The fees are estimated at $37.3 million annually and will recover the costs associated with the Medicare Survey and Certification program's revisit surveys. The fees will take effect on the date of publication of the final rule and will be in effect until the date that the continued authority provided by Congress expires. At the time of publication of this regulation the applicable date is September 30, 2007. If no legislation is enacted, the fees are not retroactive to the beginning of the fiscal year. Any provider or supplier that has a revisit survey conducted on or after the date of publication will be assessed a revisit user fee and will be notified of the assessment upon data system reconciliation which can occur following the closing of the fiscal year. The fees will be available to CMS until expended. The revisit user fee is included in the President's proposed FY 2008 budget. We note through the publication of this final rule that if authority for the revisit user fee is continued, we will use the current fee schedule in this rule for the assessment of such fees until such time as a new fee schedule notice is proposed and published in final form.
Schneider, Harald J; Buchfelder, Michael; Wallaschofski, Henri; Luger, Anton; Johannsson, Gudmundur; Kann, Peter H; Mattsson, Anders
2015-12-01
There is no single clinical marker to reliably assess the clinical response to growth hormone replacement therapy (GHRT) in adults with growth hormone deficiency (GHD). The objective of this study was to propose a clinical response score to GHRT in adult GHD and to establish clinical factors that predict clinical response. This was a prospective observational cohort study from the international KIMS database (Pfizer International Metabolic Database). We included 3612 adult patients with GHD for proposing the response score and 844 patients for assessing predictors of response. We propose a clinical response score based on changes in total cholesterol, waist circumference and QoL-AGHDA quality of life measurements after 2 years of GHRT. A score point was added for each quintile of change in each variable, resulting in a sum score ranging from 3 to 15. For clinical response at 2 years, we analysed predictors at baseline and after 6 months using logistic regression analyses. In a baseline prediction model, IGF1, QoL-AGHDA, total cholesterol and waist circumference predicted response, with worse baseline parameters being associated with a favourable response (AUC 0.736). In a combined baseline and 6-month prediction model, baseline QoL-AGHDA, total cholesterol and waist circumference, and 6-month change in waist circumference were significant predictors of response (AUC 0.815). A simple clinical response score might be helpful in evaluating the success of GHRT. The baseline prediction model may aid in the decision to initiate GHRT and the combined prediction model may be helpful in the decision to continue GHRT. © 2015 European Society of Endocrinology.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-01
... Effectiveness of Proposed Rule Change Regarding Cancellation or Rescheduling Fees for Qualification Examinations and Continuing Education Sessions July 26, 2011. Pursuant to Section 19(b)(1) of the Securities... for qualification examinations and continuing education sessions. Specifically, the proposed rule...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-21
... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Proposed Information...: The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden.../or continuing information collections, as required by the Paperwork Reduction Act of 1995. DATES...
NASA Technical Reports Server (NTRS)
Eastman, L. F.; Wicks, G. W.
1987-01-01
This project was proposed to be a three-year contract, but was cut off after one year (1987) of support. Sufficient progress was made to allow continuation for a year on minimal internal funds before proper support levels were received from a combination of ONR, RADC, and IBM contracts at about the start of 1989. A major DARPA grant, expected to start August 1, 1990, will sharply expand this effort to include several faculty members. During the course of this project, two students did thesis research, one Ph.D. on lasers and one M.S. on high speed photodetectors. These theses were finished in September 1988, nine months after the contract was cut off. This report covers excerpts from those theses as well as information obtained on other programs since that time.
NASA Astrophysics Data System (ADS)
Tsiok, E. N.; Fomin, Y. D.; Ryzhov, V. N.
2018-01-01
Despite about forty years of investigations, the nature of the melting transition in two dimensions is not completely clear. In the framework of the most popular Berezinskii-Kosterlitz-Thouless-Halperin-Nelson-Young (BKTHNY) theory, 2D systems melt through two continuous Berezinskii-Kosterlitz-Thouless (BKT) transitions with intermediate hexatic phase. The conventional first-order transition is also possible. On the other hand, recently on the basis of computer simulations the new melting scenario was proposed with continuous BKT type solid-hexatic transition and first order hexatic-liquid transition. However, in the simulations the hexatic phase is extremely narrow that makes its study difficult. In the present paper, we propose to apply the random pinning to investigate the hexatic phase in more detail. The results of molecular dynamics simulations of two dimensional system having core-softened potentials with narrow repulsive step which is similar to the soft disk system are outlined. The system has a small fraction of pinned particles giving quenched disorder. Random pinning widens the hexatic phase without changing the melting scenario and gives the possibility to study the behavior of the diffusivity and order parameters in the vicinity of the melting transition and inside the hexatic phase.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-20
... Organizations; International Securities Exchange, LLC; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Amend Rule 604, Continuing Education for Registered Persons, and To Adopt a... proposing to amend Rule 604 to clarify the current continuing education requirements for registered persons...
76 FR 22672 - Shoshone Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-22
... Committee Act. The purpose of the meeting is to continue to review Title II project proposals and start... to the public. The following business will be conducted: (1) Continue to review Title II project proposals (2) Start selecting projects to recommend to the Designated Federal Official (3) Make a decision...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-13
... Amend the Quantitative Continued Listing Standards Applicable to Companies Listed Under Sections 102.01C...-4 thereunder,\\2\\ a proposed rule change to amend the quantitative continued listing standards...\\ companies with such securities listed on the Exchange must also meet certain quantitative financial...
Computation of non-monotonic Lyapunov functions for continuous-time systems
NASA Astrophysics Data System (ADS)
Li, Huijuan; Liu, AnPing
2017-09-01
In this paper, we propose two methods to compute non-monotonic Lyapunov functions for continuous-time systems which are asymptotically stable. The first method is to solve a linear optimization problem on a compact and bounded set. The proposed linear programming based algorithm delivers a CPA1
Forecasting continuously increasing life expectancy: what implications?
Le Bourg, Eric
2012-04-01
It has been proposed that life expectancy could linearly increase in the next decades and that median longevity of the youngest birth cohorts could reach 105 years or more. These forecasts have been criticized but it seems that their implications for future maximal lifespan (i.e. the lifespan of the last survivors) have not been considered. These implications make these forecasts untenable and it is less risky to hypothesize that life expectancy and maximal lifespan will reach an asymptotic limit in some decades from now. Copyright © 2012 Elsevier B.V. All rights reserved.
Peng, Jen -Chieh; Qiu, Jian -Wei
2016-09-01
The Drell-Yan process, proposed over 45 years ago by Sid Drell and Tung-Mow Yan to describe high-mass lepton-pair production in hadron-hadron collision, has played an important role in validating QCD as the correct theory for strong interaction. This process has also become a powerful tool for probing the partonic structures of hadrons. The Drell-Yan mechanism has led to the discovery of new particles, and will continue to be an important tool to search for new physics. In this study, we review some highlights and future prospects of the Drell-Yan process.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-14
...EPA is proposing to determine that the Birmingham, Alabama, nonattainment area for the 2006 24-hour fine particulate matter (PM2.5) National Ambient Air Quality Standard (NAAQS) has attained the 2006 24-hour PM2.5 NAAQS. This proposed determination is based upon complete, quality assured, quality controlled, and certified ambient air monitoring data for the years 2007-2009 showing that this area has monitored attainment of the 2006 24-hour PM2.5 NAAQS. If this proposed determination is made final, the requirement for the State of Alabama to submit an attainment demonstration and associated reasonably available control measures (RACM), reasonable further progress (RFP) plan, contingency measures, and other planning State Implementation Plans (SIPs) related to attainment of the 2006 24-hour PM2.5 standard for the Birmingham, Alabama, PM2.5 nonattainment area, shall be suspended for as long as this area continues to meet the 2006 24-hour PM2.5 NAAQS.
NASA Astrophysics Data System (ADS)
Kiani, Keivan
2014-06-01
Novel nonlocal discrete and continuous models are proposed for dynamic analysis of two- and three-dimensional ensembles of single-walled carbon nanotubes (SWCNTs). The generated extra van der Waals forces between adjacent SWCNTs due to their lateral motions are evaluated via Lennard-Jones potential function. Using a nonlocal Rayleigh beam model, the discrete and continuous models are developed for both two- and three-dimensional ensembles of SWCNTs acted upon by transverse dynamic loads. The capabilities of the proposed continuous models in capturing the vibration behavior of SWCNTs ensembles are then examined through various numerical simulations. A reasonably good agreement between the results of the continuous models and those of the discrete ones is also reported. The effects of the applied load frequency, intertube spaces, and small-scale parameter on the transverse dynamic responses of both two- and three-dimensional ensembles of SWCNTs are explained. The proposed continuous models would be very useful for dynamic analyses of large populated ensembles of SWCNTs whose discrete models suffer from both computational efforts and labor costs.
Raus, Kasper; Chambaere, Kenneth; Sterckx, Sigrid
2016-06-29
Continuous deep sedation at the end of life is a practice that has been the topic of considerable ethical debate, for example surrounding its perceived similarity or dissimilarity with physician-assisted dying. The practice is generally considered to be legal as a form of symptom control, although this is mostly only assumed. France has passed an amendment to the Public Health Act that would grant certain terminally ill patients an explicit right to continuous deep sedation until they pass away. Such a framework would be unique in the world. In this paper we will highlight and reflect on four relevant aspects and shortcomings of the proposed bill. First, that the bill suggests that continuous deeps sedation should be considered as a sui generis practice. Second, that it requires that sedation should always be accompanied by the withholding of all artificial nutrition and hydration. In the most recently amended version of the legal proposal it is stated that life sustaining treatments are withheld unless the patient objects. Third, that the French bill would not require that the suffering for which continuous deep sedation is initiated is unbearable. Fourth, the question as to whether the proposal should be considered as a way to avoid having to decriminalise euthanasia and/or PAS or, on the contrary, as a veiled way to decriminalise these practices. The French proposal to amend the Public Health Act to include a right to continuous deep sedation for some patients is a unique opportunity to clarify the legality of continuous deep sedation as an end-of-life practice. Moreover, it would recognize that the practice of continuous deep sedation raises ethical and legal issues that are different from those raised by symptom control on the one hand and assisted dying on the other hand. Nevertheless, there are still various issues of significant ethical concern in the French legislative proposal.
Bread and Butter Astro-kinetics with GEST
NASA Astrophysics Data System (ADS)
Rhie, S. H.
2001-12-01
The Galactic Exoplanet Survey Telescope (GEST) is a proposed MIDEX mission to survey microlensing extrasolar planets of Mars mass and upward. GEST/MIDEX telescope has a relatively small diameter (1m) and a large focal plane ( 2.2 square degrees) filled with 0.6 billion red-sensitive 10 micron pixels with large well-depths (> 100,000 electrons). The polar orbit allows continuous view of the target field near the Galactic center and stable PSFs necessary for efficient dithering and undersampling. The mission is designed to be able to monitor about 100 million stars continuously 8 months per year for three consecutive years, and this will produce 50,000 close-in transit giant planets as well as terrestrial microlensing planets and free-floating planets. An impressive database of variable stars will be one of the biproducts of such a massive survey as is well proved from ground-based microlensing surveys. Here we analyse the effects and utilities of astrometric and parallactic measurements that are more or less uniquely allowed by the fine angular resolutions and high precision photometries of the survey from space.
NSF Programs That Support Research in the Two-Year College Classroom
NASA Astrophysics Data System (ADS)
Carter, V.; Ryan, J. G.; Singer, J.
2011-12-01
The National Science Foundation recognizes the significant role provided by two-year institutions in providing high quality STEM courses to large numbers of students. For some students the STEM courses completed while attending a two-year institution represent the only STEM courses a student may take; for others the courses serve as the foundation to continue on into a STEM major at a four-year institution; and some students complete STEM courses that lead directly into the workforce. Several programs in the Division of Undergraduate Research, including the Advanced Technological Education (ATE) program, STEM Talent Expansion Program (STEP), and the Transforming Undergraduate Education in STEM (TUES) program, support the inclusion of student research experiences at two-year institutions. Information about these programs and examples of successful funded projects will be provided. Resources for faculty considering applying for support will be shared with special attention to a faculty development program designed to help faculty learn about funding opportunities and prepare proposals for submission to the TUES and ATE programs.
NASA Technical Reports Server (NTRS)
Atwood, Christopher A.
1993-01-01
The June 1992 to May 1993 grant NCC-2-677 provided for the continued demonstration of Computational Fluid Dynamics (CFD) as applied to the Stratospheric Observatory for Infrared Astronomy (SOFIA). While earlier grant years allowed validation of CFD through comparison against experiments, this year a new design proposal was evaluated. The new configuration would place the cavity aft of the wing, as opposed to the earlier baseline which was located immediately aft of the cockpit. This aft cavity placement allows for simplified structural and aircraft modification requirements, thus lowering the program cost of this national astronomy resource. Three appendices concerning this subject are presented.
Overview of research in progress at the Center of Excellence
NASA Technical Reports Server (NTRS)
Wandell, Brian A.
1993-01-01
The Center of Excellence (COE) was created nine years ago to facilitate active collaboration between the scientists at Ames Research Center and the Stanford Psychology Department. Significant interchange of ideas and personnel continues between Stanford and participating groups at NASA-Ames; the COE serves its function well. This progress report is organized into sections divided by project. Each section contains a list of investigators, a background statement, progress report, and a proposal for work during the coming year. The projects are: Algorithms for development and calibration of visual systems, Visually optimized image compression, Evaluation of advanced piloting displays, Spectral representations of color, Perception of motion in man and machine, Automation and decision making, and Motion information used for navigation and control.
Fernandez-Mendoza, Julio
2017-01-01
It was first proposed in the late 1990s that objective markers of sleep disturbance could serve as an index of the biological severity of insomnia. In 2013, a heuristic model of two insomnia phenotypes based on objective sleep duration was proposed. Herein, we review the studies conducted in the past 3 years on the insomnia with short sleep duration phenotype and its implications for a clinical research agenda. Studies have shown that insomnia with objective short sleep duration is associated with physiologic hyperarousal and cardiometabolic and neurocognitive morbidity, whereas insomnia with normal sleep duration is not. Both insomnia phenotypes are associated with psychiatric morbidity albeit through different psychobiological mechanisms. Novel recent studies have included occupational outcomes, developmental approaches, at-home objective sleep testing, diagnostic accuracy measures, and response to cognitive-behavioral treatment. Accumulating evidence in the past years has continued to support that insomnia with short sleep duration is a more severe phenotype of the disorder associated with physiologic changes, significant morbidity and mortality and, potentially, a differential response to treatment.
Taylor, D; Woods, N
2001-01-01
In this first chapter, we trace the historical roots of nursing research and scholarship focused on protecting and promoting women's health. Beginning with Florence Nightingale, modern nursing's first researcher, who focused on the health impact of women's daily lives through her detailed observations of human behavior. More recently, nursing's contributions to women's health over the past 30 years have redefined women's health, proposed new frameworks for understanding women's health; provided reviews of the women's health literature across disciplines; developed communities of nurse scholars and researchers focused on new areas of women's health research; generated and expanded the knowledge base for women's health practice and education; promoted a global view of women's health; and proposed new models for women's health care delivery. Clearly, a community of nursing scholars, developed over the past 25 years, has contributed to advancing women's health knowledge and improving the health and well-being of women. Without the benefit of a crystal ball, we suggest that nursing will continue to provide leadership in the conduct and the application of research to improve women's health and women's lives.
NASA Astrophysics Data System (ADS)
Yuki, Akiyama; Satoshi, Ueyama; Ryosuke, Shibasaki; Adachi, Ryuichiro
2016-06-01
In this study, we developed a method to detect sudden population concentration on a certain day and area, that is, an "Event," all over Japan in 2012 using mass GPS data provided from mobile phone users. First, stay locations of all phone users were detected using existing methods. Second, areas and days where Events occurred were detected by aggregation of mass stay locations into 1-km-square grid polygons. Finally, the proposed method could detect Events with an especially large number of visitors in the year by removing the influences of Events that occurred continuously throughout the year. In addition, we demonstrated reasonable reliability of the proposed Event detection method by comparing the results of Event detection with light intensities obtained from the night light images from the DMSP/OLS night light images. Our method can detect not only positive events such as festivals but also negative events such as natural disasters and road accidents. These results are expected to support policy development of urban planning, disaster prevention, and transportation management.
Continuous-variable quantum homomorphic signature
NASA Astrophysics Data System (ADS)
Li, Ke; Shang, Tao; Liu, Jian-wei
2017-10-01
Quantum cryptography is believed to be unconditionally secure because its security is ensured by physical laws rather than computational complexity. According to spectrum characteristic, quantum information can be classified into two categories, namely discrete variables and continuous variables. Continuous-variable quantum protocols have gained much attention for their ability to transmit more information with lower cost. To verify the identities of different data sources in a quantum network, we propose a continuous-variable quantum homomorphic signature scheme. It is based on continuous-variable entanglement swapping and provides additive and subtractive homomorphism. Security analysis shows the proposed scheme is secure against replay, forgery and repudiation. Even under nonideal conditions, it supports effective verification within a certain verification threshold.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-16
... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Proposed Information Collection; Comment Request; Fisheries in the Western Pacific; Proposed Information Collection; Seabird... opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork...
Jones, Alison; Jones, Kelly; Holmes, Sheila; Ewers, Leon; Cabianca, Tiberio
2013-03-01
The aim of this work is to assess the possible radiological impact on the population of the United Kingdom (UK) from new nuclear power stations proposed for up to eight sites in England and Wales. The radiological impact was measured in terms of collective dose to the UK, European and world populations from a single year's discharge integrated to 500 and 100 000 years and the annual dose to an average member of the UK population (known as the per-caput dose). The doses were calculated for two reactor types, UK EPR™ and AP1000™, using the annual expected discharges estimated by the designers of the reactors and assuming two reactors per site. In addition, typical individual doses to adults living close to the sites were calculated on the basis of continuous discharges for 60 years (the assumed lifetime of the reactors). The dose to a representative person (previously known as the critical group) was not calculated, as this has been done elsewhere. The assessments were carried out using the software program PC-CREAM 08(®) which implements the updated European Commission methodology for assessing the radiological impact of routine releases of radionuclides to the environment. The collective dose truncated to 500 years to the UK population was estimated to be 0.5 manSv assuming UK EPR reactors on all sites and 0.6 manSv assuming AP1000s on three sites with UK EPRs on the other sites. The most significant contribution to the collective dose to the UK population is due to the global circulation of carbon-14 released to the atmosphere. The annual dose to an average member of the UK population from all sites was calculated to be around 10 nSv y(-1) and would therefore contribute little to an individual's total radiation dose. All the calculated doses to a typical adult living near the sites assuming continuous discharges for 60 years were found to be below 1 μSv y(-1).
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-14
... 1219-AB64 Lowering Miners' Exposure to Respirable Coal Mine Dust, Including Continuous Personal Dust... comment period on the proposed rule addressing Lowering Miners' Exposure to Respirable Coal Mine Dust...), MSHA published a proposed rule, Lowering Miners' Exposure to Respirable Coal Mine Dust, Including...
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Applications and proposals lacking definite plans for involvement of human subjects. 219.118 Section 219.118 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219...
32 CFR 219.123 - Early termination of research support: Evaluation of applications and proposals.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Early termination of research support: Evaluation of applications and proposals. 219.123 Section 219.123 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-14
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995.
NASA Astrophysics Data System (ADS)
Van Noten, Koen; Lecocq, Thomas
2016-04-01
Estimating the resonance frequency (f0) and amplification factor of unconsolidated sediments by H/V spectral ratio (HVSR) analysis of seismic ambient noise has been widely used since Nakamura's proposal in 1989. To measure f0 properly, Nakamura suggested to perform microzonation surveys at night when the artificial microtremor is small and does not fully disrupt the ambient seismic noise. As nightly fieldwork is not always a reasonable demand, we propose an alternative workflow of Nakamura's technique to improve the quality of HVSR results obtained by ambient noise measurements of mobile stations during the day. This new workflow includes the automated H/V calculation of continuous seismic data of a stationary or permanent station installed near the microzonation site for as long as the survey lasts in order to control the error in the HVSR analysis obtained by the mobile stations. In this presentation, we apply this workflow on one year of seismic data at two different case studies; i.e. a rural site with a shallow bedrock depth of 30 m and an urban site (Brussels, capital of Belgium, bedrock depth of 110 m) where human activity is continuous 24h/day. By means of an automated python script, the fundamental peak frequency and the H/V amplitude are automatically picked from H/V spectra that are calculated from 50% overlapping, 30 minute windows during the whole year. Afterwards, the f0 and amplitude picks are averaged per hour/per day for the whole year. In both case studies, the H/V amplitude and the fundamental frequencies range considerable, up to ˜15% difference between the daily and nightly measurements. As bedrock depth is known from boreholes at both sites, we concluded that the nightly picked f0 is the true one. Our results thus suggest that changes in the determined f0 and H/V amplitude are dominantly caused by the human behaviour which is stored in the ambient seismic noise (e.g. later onset of traffic in a weekend, quiet Sundays, differences between daily/nightly activity,…). Consequently, performing a continuous HVSR analysis next to your microzonation site allows you to characterise the deviation of the measured f0 to the true f0 during the period of investigation (in our case during the whole year)! As mobile stations are affected by the same variation stored in the ambient noise, then a correction factor can be applied on the calculated f0 of individual measurements during the microzonation survey and a proper Vs can be estimated. Based on these results we recommend that microzonation with mobile stations should always be accompanied by a stationary seismic station to characterise the ambient noise and to control the error.
Leadership and Funding: Changes Ahead for Agricultural Safety and Health.
Murphy, Dennis J; Lee, Barbara C
2018-01-01
For the last several decades, financial support for agricultural safety and health programs and professionals has primarily been covered by public dollars through federal and state government grant programs and appropriations. This federal and state funding provided a tremendous boost to farm safety and health professionals and program efforts for 30+ years and has provided the foundation and structure for current agricultural safety and health efforts and activities. However, there is reason to question long-term sustainability of a sufficient level of federal and state dollars for agricultural safety and health. Public funding for agricultural safety and health has never quite kept up to inflation, but even more ominous is that the entire agricultural safety and health program has been proposed for elimination each year by the White House budget beginning with the fiscal year 2012. It seems prudent, perhaps even imperative, for the agricultural safety and health community to find alternative support mechanisms. We suggest that now is a great time for agricultural businesses, services, and organizations to step up their financial support. Fortunately, several positive examples have recently surfaced within the agricultural community. As the agricultural industry continues to be a dominant enterprise in the United States, the integration of significant funding and the role of leadership from within the industry must continue to expand.
The GGOS Global Space Geodesy Network and its Evolution
NASA Astrophysics Data System (ADS)
Pearlman, M. R.; Pavlis, E. C.; Ma, C.; Noll, C. E.; Neilan, R. E.; Stowers, D. A.; Wetzel, S.
2013-12-01
The improvements in the reference frame and other space geodesy data products spelled out in the GGOS 2020 plan will evolve over time as new space geodesy sites enhance the global distribution of the network and new technologies are implemented at the sites thus enabling improved data processing and analysis. The goal of 30 globally distributed core sites with VLBI, SLR, GNSS and DORIS (where available) will take time to materialize. Co-location sites with less than the full core complement will continue to play a very important role in filling out the network while it is evolving and even after full implementation. GGOS through its Call for Participation, bi-lateral and multi-lateral discussions and work through the IAG Services has been encouraging current groups to upgrade and new groups to join the activity. Simulations examine the projected accuracy and stability of the network that would exist in five- and ten-years time, were the proposed expansion to fully materialize by then. Over the last year additional sites have joined the GGOS network, and ground techniques have continued to make progress in new technology systems. This talk will give an update on the current expansion of the global network and the projection for the network configuration that we forecast over the next 10 years.
Schenck, C H; Mahowald, M W
1995-11-01
A case of childhood-onset somnambulism is reported in which a 43-year-old man presented with repeated sleep-related injuries incurred during violent nocturnal activity, which included frenzied running, throwing punches and wielding knives. He had also driven an automobile a long distance during a presumed somnambulistic state. His wife had been repeatedly injured, and she felt that her life was threatened by his nocturnal violence 2-3 times yearly. Polysomnography (PSG) documented multiple episodes of complex and violent behaviors arising exclusively from stage 3/4 sleep, thus confirming the diagnosis of somnambulism. Other causes of sleep-related violence were excluded. The patient responded promptly to treatment with bedtime clonazepam, and benefit was maintained at 5-year follow-up. Although this strictly clinical case did not have any legal repercussions, it does carry forensic implications, particularly when placed in the context of the published medical literature on PSG-documented parasomnias (somnambulism, rapid eye movement sleep behavior disorder) containing explicit examples of recurrent violence, at times life-threatening, directed toward the bed partner and others. Thus, a new medical-legal concept is proposed, consisting of "parasomnia with continuing danger" as a noninsane automatism. Treatment guidelines, within the context of forensic medicine, are presented.
A food industry perspective on folic acid fortification.
Schaller, D R; Olson, B H
1996-03-01
The U.S. Public Health Service (PHS) has recommended that all women of childbearing years, capable of becoming pregnant, consume 400 micrograms folic acid/d to reduce their risk of having a neural tube defect (NTD)-affected pregnancy. The U.S. Food and Drug Administration subsequently proposed a folate fortification scheme for cereal grains, which also allowed the continued fortification of breakfast cereals at 0.1 mg per serving. To determine the contribution of ready-to-eat breakfast cereals (RTEC) to folate intakes in women of childbearing years, data were analyzed from the U.S. Department of Agriculture's 1989-1991 Continuing Survey of Food Intakes by Individuals and 1987-1988 Nationwide Food Consumption Survey. Women consuming RTEC have higher intakes of folate than women reporting no RTEC consumption. Recent reports indicate that most women are unaware of the PHS recommendation to consume more folate, and many health professionals are not advising women of the need to consume adequate folate during childbearing years. The food industry has been an effective communicator of health and nutrition messages and should be encouraged to raise awareness about the role of folate in NTDs. Better analysis also needs to be conducted to identify women at risk of low folate intakes, so that targeted education efforts can be made and appropriate vehicles identified for delivering folate to these women.
Amaral, Ricardo Abrantes; Malbergier, André; Lima, Danielle Ruiz; Santos, Verena Castellani Vitor; Gorenstein, Clarice; Andrade, Arthur Guerra de
The aim of this study was to investigate whether cognitive variables proposed by the protection motivation theory (PMT) were predictive of occasional and frequent intention to drive after drinking in medical students. One hundred fifty-five students attending preclinical years at a Medical School in São Paulo, Brazil, participated in the study. They were asked about their last month substance use, history of drinking and driving, including driving after binge drinking, and risk perceptions based on a self-report questionnaire with statements about protection motivation, threat, and coping appraisals from the PMT model. Fifty-two students (33%) had previous experience of driving after drinking during the last year, and 54 students (35%) reported intention to drive after drinking within the next year. Regression analysis showed that higher scores in perception of personal vulnerability to risks were associated with occasional and frequent intention to continue pursuing this particular behavior. Poorer evaluations about short-term consequences of alcohol consumption and cognitions regarding external rewards were significantly associated with reported intention to continue driving after drinking. Considering the social and health impact of alcohol-impaired behaviors, our findings suggest the need of interventional efforts focused in increasing students' awareness about the negative consequences of drinking and driving aiming to enhance their motivation towards more adaptive behaviors.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rockett, L.R.
1985-01-01
The study evaluates the operation of the Price-Anderson Act in the light of 10 years of experience and the changes that have occurred during the period in the law and regulations and in the nuclear and insurance industries. It provides an independent analysis of various proposals to extend or amend the Act prior to its 1987 expiration. The five chapters deal with historical background and scope, financial protection under the Act, financial protection without the Act, legislative goals and issues, and alternative proposals. The report concludes that no scheme can fully satisfy all of the criteria, bu a careful balancingmore » will depend upon congressional decision on the extent to which federal policy should encourage continued participation by private industry in the nuclear field. Selected footnotes follow each chapter.« less
Just, Pierre-Alexandre; Verkarre, Virginie; Mansuet-Lupo, Audrey; Rabant, Marion; Daniliuc, Cristina; Radenen, Brigitte; Harent, Marion; Cassanelli, Lucien; Cherel, Éric; Javaux, Hubert; Tesniere, Antoine; Terris, Benoît; Badoual, Cécile
2016-08-01
At the Paris Descartes medicine faculty, we tested some newly developed tools to enhance the pedagogic value of the pathology teaching. In our faculty, this teaching is largely multidisciplinary and integrated in various teaching units; a large part is dedicated to practice works with thirteen 90min sessions. Virtual slides have been used for years in numerous medicine faculties; we successfully implemented this tool by adding contextual annotations, which facilitate students revising. We showed that rewarding students' assiduity enhanced their exam success. To do so, we now propose a short continuous assessment exam at the beginning of each practice session in the form of electronic multi-choice questions. Finally, we now propose a completely computerized final exam, on touchpads, that enhanced its docimologic value. Copyright © 2016 Elsevier Masson SAS. All rights reserved.
Decision Making in Kidney Paired Donation Programs with Altruistic Donors*
Li, Yijiang; Song, Peter X.-K.; Leichtman, Alan B.; Rees, Michael A.; Kalbfleisch, John D.
2014-01-01
In recent years, kidney paired donation (KPD) has been extended to include living non-directed or altruistic donors, in which an altruistic donor donates to the candidate of an incompatible donor-candidate pair with the understanding that the donor in that pair will further donate to the candidate of a second pair, and so on; such a process continues and thus forms an altruistic donor-initiated chain. In this paper, we propose a novel strategy to sequentially allocate the altruistic donor (or bridge donor) so as to maximize the expected utility; analogous to the way a computer plays chess, the idea is to evaluate different allocations for each altruistic donor (or bridge donor) by looking several moves ahead in a derived look-ahead search tree. Simulation studies are provided to illustrate and evaluate our proposed method. PMID:25309603
NASA Technical Reports Server (NTRS)
Schmid, Beat
2005-01-01
The Bay Area Environmental Research Institute (BAER) scientists have worked with the NASA Ames Research Center sunphotometer group led by Dr. Philip Russell for many years researching the climatic effects of aerosol particles in the stratosphere and troposphere. We have continued to work with the NASA Ames sunphotometer group in research activities representing funded, peer-reviewed proposals to NASA, NOAA and DOE. The activities are described in those proposals and also in the documents provided to the Grants Office earlier. This is the final report from January 1,2002 - June 30, 2005. The report consists of a compilation of 41 peer-reviewed publications (published, in press or submitted) produced under this Cooperative Agreement and 43 first-authored conference presentations. To save paper, reprints are not included but will, of course, be provided upon request.
Tereskerz, Patricia M; Moreno, Jonathan
2005-01-01
Financial liaisons between clinical researchers, research institutions, and industrial sponsors have gained momentum in recent years. In the process, it has been argued by many that trust in the research infrastructure is being eroded by the financial conflicts of interest that emerge from these arrangements. Yet, the financial resources of industry are needed to continue technology transfer from the bench to the bedside. Policy makers and government regulators are currently struggling to determine how to best manage financial conflicts of interest that emerge from these liaisons. Various organizations and government entities have proposed different strategies. This paper explores the limitations of existing measures and recommends that a unified national agenda is needed. We propose 10 steps to develop an agenda to address financial conflicts of interest in industry-sponsored clinical research.
7 CFR 3406.19 - Proposal review-research.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 15 2010-01-01 2010-01-01 false Proposal review-research. 3406.19 Section 3406.19 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION... Review and Evaluation of a Research Proposal § 3406.19 Proposal review—research. The proposal evaluation...
7 CFR 3405.14 - Proposal review.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 15 2011-01-01 2011-01-01 false Proposal review. 3405.14 Section 3405.14 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Proposal Review and Evaluation § 3405.14 Proposal review. The proposal...
7 CFR 3405.14 - Proposal review.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 15 2012-01-01 2012-01-01 false Proposal review. 3405.14 Section 3405.14 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Proposal Review and Evaluation § 3405.14 Proposal review. The proposal...
7 CFR 3405.14 - Proposal review.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 15 2013-01-01 2013-01-01 false Proposal review. 3405.14 Section 3405.14 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Proposal Review and Evaluation § 3405.14 Proposal review. The proposal...
7 CFR 3405.14 - Proposal review.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 15 2014-01-01 2014-01-01 false Proposal review. 3405.14 Section 3405.14 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Proposal Review and Evaluation § 3405.14 Proposal review. The proposal...
NASA Astrophysics Data System (ADS)
Shao, Zhongshi; Pi, Dechang; Shao, Weishi
2017-11-01
This article proposes an extended continuous estimation of distribution algorithm (ECEDA) to solve the permutation flow-shop scheduling problem (PFSP). In ECEDA, to make a continuous estimation of distribution algorithm (EDA) suitable for the PFSP, the largest order value rule is applied to convert continuous vectors to discrete job permutations. A probabilistic model based on a mixed Gaussian and Cauchy distribution is built to maintain the exploration ability of the EDA. Two effective local search methods, i.e. revolver-based variable neighbourhood search and Hénon chaotic-based local search, are designed and incorporated into the EDA to enhance the local exploitation. The parameters of the proposed ECEDA are calibrated by means of a design of experiments approach. Simulation results and comparisons based on some benchmark instances show the efficiency of the proposed algorithm for solving the PFSP.
NASA Astrophysics Data System (ADS)
Smittarello, D.; Grandin, R.; De Chabalier, J.-B.; Doubre, C.; Deprez, A.; Masson, F.; Socquet, A.; Saad, I. A.
2016-08-01
The Asal-Ghoubbet Rift (AG Rift) in Djibouti lies in the subaerial continuation of the Aden ridge system, thereby constituting a unique location to study rifting processes and mechanisms involved in continental breakup and oceanic spreading. Continually upgraded and expanded geodetic technology has been used to record the 1978 Asal rifting event and postdiking deformation. In light of recent results obtained for the Manda Hararo-Dabbahu rifting event (2005-2010), we propose that the horizontal and vertical geodetic data can be modeled with a double source, involving a dike-like inflation component aligned along the rift axis and a spherical pressure source located at midsegment below the Fieale caldera. By revisiting the codiking data, we propose that the reservoir below Fieale could have fed, at least partially, the 1978 injection and the contemporaneous Ardoukôba eruption and potentially induced local subsidence due to magma draining out of the central reservoir. As an alternative to previously proposed viscoelastic relaxation models, we reinterpret postdiking observations using a purely elastic rheology. We determine the relative contribution of a midsegment reservoir inflation and a dike-like opening component, together with their respective time evolutions. Our results suggest that interactions between steadily accumulating tectonic strain and temporal variations in melt supply to the shallow magma plumbing system below the AG Rift may entirely explain the geodetic observations and that viscoelastic deformation processes played a minor role in the 30 years following the 1978 rifting event.
Consequences of a changing US strategy in the global HIV investment landscape.
McGillen, Jessica B; Sharp, Alana; Honermann, Brian; Millett, Gregorio; Collins, Chris; Hallett, Timothy B
2017-11-28
The global fight against HIV/AIDS in Africa has long been a focus of US foreign policy, but this could change if the federal budget for 2018 proposed by the US Office of Management and Budget is adopted. We aim to inform public and Congressional debate around this issue by evaluating the historical and potential future impact of US investment in the African HIV response. We use a previously published mathematical model of HIV transmission to characterize the possible impact of a series of financial scenarios for the historical and future AIDS response across Sub-Saharan Africa. We find that US funding has saved nearly five million adults in Sub-Saharan Africa from AIDS-related deaths. In the coming 15 years, if current numbers on antiretroviral treatment are maintained without further expansion of programs (the proposed US strategy), nearly 26 million new HIV infections and 4.4 million AIDS deaths may occur. A 10% increase in US funding, together with ambitious domestic spending and focused attention on optimizing resources, can avert up to 22 million HIV infections and save 2.3 million lives in Sub-Saharan Africa compared with the proposed strategy. Our synthesis of available evidence shows that the United States has played, and could continue to play, a vital role in the global HIV response. Reduced investment could allow more than two million avoidable AIDS deaths by 2032, whereas continued leadership by the United States and other countries could bring UNAIDS targets for ending the epidemic into reach.
Subjective and objective evaluation of visual fatigue on viewing 3D display continuously
NASA Astrophysics Data System (ADS)
Wang, Danli; Xie, Yaohua; Yang, Xinpan; Lu, Yang; Guo, Anxiang
2015-03-01
In recent years, three-dimensional (3D) displays become more and more popular in many fields. Although they can provide better viewing experience, they cause extra problems, e.g., visual fatigue. Subjective or objective methods are usually used in discrete viewing processes to evaluate visual fatigue. However, little research combines subjective indicators and objective ones in an entirely continuous viewing process. In this paper, we propose a method to evaluate real-time visual fatigue both subjectively and objectively. Subjects watch stereo contents on a polarized 3D display continuously. Visual Reaction Time (VRT), Critical Flicker Frequency (CFF), Punctum Maximum Accommodation (PMA) and subjective scores of visual fatigue are collected before and after viewing. During the viewing process, the subjects rate the visual fatigue whenever it changes, without breaking the viewing process. At the same time, the blink frequency (BF) and percentage of eye closure (PERCLOS) of each subject is recorded for comparison to a previous research. The results show that the subjective visual fatigue and PERCLOS increase with time and they are greater in a continuous process than a discrete one. The BF increased with time during the continuous viewing process. Besides, the visual fatigue also induced significant changes of VRT, CFF and PMA.
An Novel Continuation Power Flow Method Based on Line Voltage Stability Index
NASA Astrophysics Data System (ADS)
Zhou, Jianfang; He, Yuqing; He, Hongbin; Jiang, Zhuohan
2018-01-01
An novel continuation power flow method based on line voltage stability index is proposed in this paper. Line voltage stability index is used to determine the selection of parameterized lines, and constantly updated with the change of load parameterized lines. The calculation stages of the continuation power flow decided by the angle changes of the prediction of development trend equation direction vector are proposed in this paper. And, an adaptive step length control strategy is used to calculate the next prediction direction and value according to different calculation stages. The proposed method is applied clear physical concept, and the high computing speed, also considering the local characteristics of voltage instability which can reflect the weak nodes and weak area in a power system. Due to more fully to calculate the PV curves, the proposed method has certain advantages on analysing the voltage stability margin to large-scale power grid.
Liu, Chongxin; Liu, Hang
2017-01-01
This paper presents a continuous composite control scheme to achieve fixed-time stabilization for nonlinear systems with mismatched disturbances. The composite controller is constructed in two steps: First, uniformly finite time exact disturbance observers are proposed to estimate and compensate the disturbances. Then, based on adding a power integrator technique and fixed-time stability theory, continuous fixed-time stable state feedback controller and Lyapunov functions are constructed to achieve global fixed-time system stabilization. The proposed control method extends the existing fixed-time stable control results to high order nonlinear systems with mismatched disturbances and achieves global fixed-time system stabilization. Besides, the proposed control scheme improves the disturbance rejection performance and achieves performance recovery of nominal system. Simulation results are provided to show the effectiveness, the superiority and the applicability of the proposed control scheme. PMID:28406966
Smooth integral sliding mode controller for the position control of Stewart platform.
Kumar P, Ramesh; Chalanga, Asif; Bandyopadhyay, B
2015-09-01
This paper proposes the application of a new algorithm for the position control of a Stewart platform. The conventional integral sliding mode controller is a combination of nominal control and discontinuous feedback control hence the overall control is discontinuous in nature. The discontinuity in the feedback control is undesirable for practical applications due to chattering which causes the wear and tear of the mechanical actuators. In this paper the existing integral sliding mode control law for systems with matched disturbances is modified by replacing the discontinuous part by a continuous modified twisting control. This proposed controller is continuous in nature due to the combinations of two continuous controls. The desired position of the platform has been achieved using the proposed controller even in the presence of matched disturbances. The effectiveness of the proposed controller has been proved with the simulation results. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.
Swann, Don E.; Bucci, Melanie; Kuenzi, Amy J.; Alberti, Barbara N.; Schwalbe, Cecil R.; Halvorson, William L.; van Riper, Charles; Schwalbe, Cecil R.
2010-01-01
Long-term monitoring in national parks is essential to meet National Park Service and other important public goals. Terrestrial mammals are often proposed for monitoring because large mammals are of interest to visitors and small mammals are important as prey. However, traditional monitoring strategies for mammals are often too expensive and complex to sustain for long periods, particularly in small parks. To evaluate potential strategies for long-term monitoring in small parks, we conducted an intensive one-year inventory of terrestrial mammals at Coronado National Memorial, located in Arizona on the U.S.-Mexico international border, then continued less-intensive monitoring at the site for 7 additional years. During 1996-2003 we confirmed 44 species of terrestrial mammals. Most species (40) were detected in the intensive first year of the study, but we continued to detect new species in later years. Mark-recapture data on small mammals indicated large inter-annual fluctuations in population size, but no significant trend over the 7-year period. Issues associated with the international border affected monitoring efforts and increased sampling costs. Our study confirms that sustained annual monitoring of mammals is probably not feasible in small park units like Coronado. However, comparisons of our data with past studies provide insight into important changes in the mammal community since the 1970s, including an increase in abundance and diversity of grassland rodents. Our results suggest that intensive inventories every 10-20 years may be a valuable and cost-effective approach for detecting long-term trends in terrestrial mammal communities in small natural areas.
Use of generalised additive models to categorise continuous variables in clinical prediction
2013-01-01
Background In medical practice many, essentially continuous, clinical parameters tend to be categorised by physicians for ease of decision-making. Indeed, categorisation is a common practice both in medical research and in the development of clinical prediction rules, particularly where the ensuing models are to be applied in daily clinical practice to support clinicians in the decision-making process. Since the number of categories into which a continuous predictor must be categorised depends partly on the relationship between the predictor and the outcome, the need for more than two categories must be borne in mind. Methods We propose a categorisation methodology for clinical-prediction models, using Generalised Additive Models (GAMs) with P-spline smoothers to determine the relationship between the continuous predictor and the outcome. The proposed method consists of creating at least one average-risk category along with high- and low-risk categories based on the GAM smooth function. We applied this methodology to a prospective cohort of patients with exacerbated chronic obstructive pulmonary disease. The predictors selected were respiratory rate and partial pressure of carbon dioxide in the blood (PCO2), and the response variable was poor evolution. An additive logistic regression model was used to show the relationship between the covariates and the dichotomous response variable. The proposed categorisation was compared to the continuous predictor as the best option, using the AIC and AUC evaluation parameters. The sample was divided into a derivation (60%) and validation (40%) samples. The first was used to obtain the cut points while the second was used to validate the proposed methodology. Results The three-category proposal for the respiratory rate was ≤ 20;(20,24];> 24, for which the following values were obtained: AIC=314.5 and AUC=0.638. The respective values for the continuous predictor were AIC=317.1 and AUC=0.634, with no statistically significant differences being found between the two AUCs (p =0.079). The four-category proposal for PCO2 was ≤ 43;(43,52];(52,65];> 65, for which the following values were obtained: AIC=258.1 and AUC=0.81. No statistically significant differences were found between the AUC of the four-category option and that of the continuous predictor, which yielded an AIC of 250.3 and an AUC of 0.825 (p =0.115). Conclusions Our proposed method provides clinicians with the number and location of cut points for categorising variables, and performs as successfully as the original continuous predictor when it comes to developing clinical prediction rules. PMID:23802742
The Clustering of Galaxies and Dark Matter at Intermediate Redshifts
NASA Technical Reports Server (NTRS)
Jain, Bhuvnesh; Szalay, Alexander
2003-01-01
Theoretical work in the study of weak lensing was begun while the Scientific PI (Jain) was at the Johns Hopkins University. A new postdoctoral fellow, Rita Kim, was hired to work for 0.5 years on the proposed research. She was unable to join JHU until March 2001 owing to delays in her PhD work. Meanwhile PI Jain moved to the University of Pennsylvania in January 2001. Owing to the above circumstances, the work for the proposed research was delayed and was expected to be carried out in the remainder of 2001. New measures of lensing based on the magnification effect were to be investigated by Drs. Jain and Kim. The simulations needed to test the analytical computations were already in place; hence the work was expected to proceed fairly rapidly. Owing to the close proximity of JHU and UPenn, the collaborative work was expected to proceed smoothly. It was requested therefore that the funds for the first grant year (2000-2001) be transferred to the second year. Part of the funding was spent at JHU on the salary for the Postdoctoral Fellow, Rita Kim, and the remainder at the University of Pennsylvania. The work from this grant is incomplete and will be continued under another grant.
Zipf rank approach and cross-country convergence of incomes
NASA Astrophysics Data System (ADS)
Shao, Jia; Ivanov, Plamen Ch.; Urošević, Branko; Stanley, H. Eugene; Podobnik, Boris
2011-05-01
We employ a concept popular in physics —the Zipf rank approach— in order to estimate the number of years that EU members would need in order to achieve "convergence" of their per capita incomes. Assuming that trends in the past twenty years continue to hold in the future, we find that after t≈30 years both developing and developed EU countries indexed by i will have comparable values of their per capita gross domestic product {\\cal G}_{i,t} . Besides the traditional Zipf rank approach we also propose a weighted Zipf rank method. In contrast to the EU block, on the world level the Zipf rank approach shows that, between 1960 and 2009, cross-country income differences increased over time. For a brief period during the 2007-2008 global economic crisis, at world level the {\\cal G}_{i,t} of richer countries declined more rapidly than the {\\cal G}_{i,t} of poorer countries, in contrast to EU where the {\\cal G}_{i,t} of developing EU countries declined faster than the {\\cal G}_{i,t} of developed EU countries, indicating that the recession interrupted the convergence between EU members. We propose a simple model of GDP evolution that accounts for the scaling we observe in the data.
32 CFR 724.218 - Limitation-Continuance and Postponements.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 5 2010-07-01 2010-07-01 false Limitation-Continuance and Postponements. 724... Limitation—Continuance and Postponements. (a) A continuance of a discharge review hearing may be authorized... continuance is of reasonable duration and is essential to achieving a full and fair hearing. When a proposal...
Smith, F; Singleton, A; Hilton, S
1998-10-01
The accreditation and provision of continuing education for general practitioners (GPs) is set to change with new proposals from the General Medical Council, the Government, and the Chief Medical Officer. To review the theories, policies, strategies, and effectiveness in GP continuing education in the past 10 years. A systematic review of the literature by computerized and manual searches of relevant journals and books. Educational theory suggests that continuing education (CE) should be work-based and use the learner's experiences. Audit can play an important role in determining performance and needs assessment, but at present is largely a separate activity. Educational and professional support, such as through mentors or co-tutors, has been successfully piloted but awaits larger scale evaluation. Most accredited educational events are still the postgraduate centre lecture, and GP Tutors have a variable role in CE management and provision. Controlled trials of CE strategies suggest effectiveness is enhanced by personal feedback and work prompts. Qualitative studies have demonstrated that education plays only a small part in influencing doctors' behavior. Maintaining good clinical practice is on many stakeholders' agendas. A variety of methods may be effective in CE, and larger scale trials or evaluations are needed.
Continued Bullying Victimization in Adolescents: Maladaptive Schemas as a Mediational Mechanism.
Calvete, Esther; Fernández-González, Liria; González-Cabrera, Joaquín M; Gámez-Guadix, Manuel
2018-03-01
Bullying victimization in adolescence is a significant social problem that can become persistent over time for some victims. However, there is an overall paucity of research examining the factors that contribute to continued bullying victimization. Schema therapy proposes a model that can help us understand why bullying victimization can be persistent for some victims. This study examines the role of maladaptive schemas, the key concept in schema therapy, as a mechanism of continued bullying victimization. The hypothesis was that maladaptive schemas of rejection mediate the predictive association between victimization in both the family and at school and future bullying victimization. Social anxiety was also considered, as previous research suggests that it can increase the risk of victimization. The participants were 1328 adolescents (45% female) with a mean age of 15.05 years (SD = 1.37), who completed questionnaires at three time points with a 6-month interval between them. Time 2 maladaptive schemas of rejection significantly mediated the predictive association from Time 1 bullying victimization, family abuse and social anxiety to Time 3 bullying victimization. The findings pertaining to potentially malleable factors, such as maladaptive schemas that maintain continued interpersonal victimization, have important implications for prevention and treatment strategies with adolescents.
African dust and the demise of Caribbean coral reefs
Shinn, E.A.; Smith, G.W.; Prospero, J.M.; Betzer, P.; Hayes, M.L.; Garrison, V.; Barber, R.T.
2000-01-01
The vitality of Caribbean coral reefs has undergone a continual state of decline since the late 1970s, a period of time coincidental with large increases in transatlantic dust transport. It is proposed that the hundreds of millions of tons/year of soil dust that have been crossing the Atlantic during the last 25 years could be a significant contributor to coral reef decline and may be affecting other ecosystems. Benchmark events, such as near synchronous Caribbean-wide mortalities of acroporid corals and the urchin Diadema in 1983, and coral bleaching beginning in 1987, correlate with the years of maximum dust flux into the Caribbean. Besides crustal elements, in particular Fe, Si, and aluminosilicate clays, the dust can serve as a substrate for numerous species of viable spores, especially the soil fungus Aspergillus. Aspergillus sydowii, the cause of an ongoing Caribbean-wide seafan disease, has been cultured from Caribbean air samples and used to inoculate sea fans.
Simulation-Based Prediction of Equivalent Continuous Noises during Construction Processes
Zhang, Hong; Pei, Yun
2016-01-01
Quantitative prediction of construction noise is crucial to evaluate construction plans to help make decisions to address noise levels. Considering limitations of existing methods for measuring or predicting the construction noise and particularly the equivalent continuous noise level over a period of time, this paper presents a discrete-event simulation method for predicting the construction noise in terms of equivalent continuous level. The noise-calculating models regarding synchronization, propagation and equivalent continuous level are presented. The simulation framework for modeling the noise-affected factors and calculating the equivalent continuous noise by incorporating the noise-calculating models into simulation strategy is proposed. An application study is presented to demonstrate and justify the proposed simulation method in predicting the equivalent continuous noise during construction. The study contributes to provision of a simulation methodology to quantitatively predict the equivalent continuous noise of construction by considering the relevant uncertainties, dynamics and interactions. PMID:27529266
Simulation-Based Prediction of Equivalent Continuous Noises during Construction Processes.
Zhang, Hong; Pei, Yun
2016-08-12
Quantitative prediction of construction noise is crucial to evaluate construction plans to help make decisions to address noise levels. Considering limitations of existing methods for measuring or predicting the construction noise and particularly the equivalent continuous noise level over a period of time, this paper presents a discrete-event simulation method for predicting the construction noise in terms of equivalent continuous level. The noise-calculating models regarding synchronization, propagation and equivalent continuous level are presented. The simulation framework for modeling the noise-affected factors and calculating the equivalent continuous noise by incorporating the noise-calculating models into simulation strategy is proposed. An application study is presented to demonstrate and justify the proposed simulation method in predicting the equivalent continuous noise during construction. The study contributes to provision of a simulation methodology to quantitatively predict the equivalent continuous noise of construction by considering the relevant uncertainties, dynamics and interactions.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Evaluation and disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. 219.120 Section 219.120 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED...
NASA Astrophysics Data System (ADS)
Tang, Jianguan; Li, Liang; Guo, Huiyong; Yu, Haihu; Wen, Hongqiao; Yang, Minghong
2017-04-01
A distributed acoustic sensing system (DAS) with low-coherence ASE and Michelson interferometer based on continuous width-band ultra-weak fiber Bragg grating (UW-FBG) array is proposed and experimentally demonstrated. The experimental result shows that the proposed system has better performance in detecting acoustic waves than the conventional hydrophone.
ERIC Educational Resources Information Center
Sorebo, Oystein; Halvari, Hallgier; Gulli, Vebjorn Flaata; Kristiansen, Roar
2009-01-01
Based on self-determination theory, this study proposes an extended information systems continuance theory in the context of teachers' utilization of e-learning technology in connection with on-site courses. In the proposed model teachers' extrinsic motivation (i.e. perceived usefulness), confirmation of pre-acceptance expectations and intrinsic…
An Immunized Aircraft Maneuver Selection System
NASA Technical Reports Server (NTRS)
Karr, Charles L.
2003-01-01
The objective of this project, as stated in the original proposal, was to develop an immunized aircraft maneuver selection (IAMS) system. The IAMS system was to be composed of computational and informational building blocks that resemble structures in natural immune systems. The ultimate goal of the project was to develop a software package that could be flight tested on aircraft models. This report describes the work performed in the first year of what was to have been a two year project. This report also describes efforts that would have been made in the final year to have completed the project, had it been continued for the final year. After introductory material is provided in Section 2, the end-of-year-one status of the effort is discussed in Section 3. The remainder of the report provides an accounting of first year efforts. Section 4 provides background information on natural immune systems while Section 5 describes a generic ar&itecture developed for use in the IAMS. Section 6 describes the application of the architecture to a system identification problem. Finally, Section 7 describes steps necessary for completing the project.
Freak Waves In The Ocean A~é We Need Continuous Measurements!
NASA Astrophysics Data System (ADS)
Liu, P.; Teng, C.; Mori, N.
Freak waves, sometimes also known as rogue waves, are a particular kind of ocean waves that displays a singular, unexpected, and unusually high wave profile with an extraordinarily large and steep trough or crest. The existence of freak waves has be- come widely accepted while it always poses severe hazard to the navy fleets, merchant marines, offshore structures, and virtually all oceanic ventures. Multitudes of seagoing vessels and mariners have encountered freak waves over the years, many had resulted in disasters. The emerging interest in freak waves and the quest to grasp an understand- ing of the phenomenon have inspired numerous theoretical conjectures in recent years. But the practical void of actual field observation on freak waves renders even the well- developed theories remain unverified. Furthermore, the present wave measurement systems, which have been in practice for the last 5 decades, are not at all designed to capture freak waves. We wish therefore to propose and petition to all oceanic scientist and engineers to consider undertaking an unprecedented but technologically feasible practice of making continuous and uninterrupted wave measurements. As freak waves can happen anywhere in the ocean and at anytime, the continuous and uninterrupted measurements at a fixed station would certainly be warranted to document the occur- rence of freak waves, if present, and thus lead to basic realizations of the underlying driving mechanisms.
Borgelt, B B; Stone, C
1999-10-01
To evaluate the impact of the proposed Ambulatory Patient Classification (APC) system on reimbursement for hospital outpatient Medicare procedures at the Massachusetts General Hospital (MGH) Department of Radiation Oncology. Treatment and cost data for the MGH Department of Radiation Oncology for the fiscal year 1997 were analyzed. This represented 66,981 technical procedures and 41 CPT-4 codes. The cost of each procedure was calculated by allocating departmental costs to the relative value units (RVUs) for each procedure according to accepted accounting principles. Net reimbursement for each CPT-4 procedure was then calculated by subtracting its cost from the allowed 1998 Boston area Medicare reimbursement or from the proposed Boston area APC reimbursement. The impact of the proposed APC reimbursement system on changes in reimbursement per procedure and on volume-adjusted changes in overall net reimbursements per procedure was determined. Although the overall effect of APCs on volume-adjusted net reimbursements for Medicare patients was projected to be budget-neutral, treatment planning revenues would have decreased by 514% and treatment delivery revenues would have increased by 151%. Net reimbursements for less complicated courses of treatment would have increased while those for treatment courses requiring more complicated or more frequent treatment planning would have decreased. Net reimbursements for a typical prostate interstitial implant and a three-treatment high-dose-rate intracavitary application would have decreased by 481% and 632%, respectively. The financial incentives designed into the proposed APC reimbursement structure could lead to compromises in currently accepted standards of care, and may make it increasingly difficult for academic institutions to continue to fulfill their missions of research and service to their communities. The ability of many smaller, low patient volume, high Medicare mix hospital-based radiation oncology departments to continue to deliver their current level of care could be compromised. APC reform may carry monetary and opportunity costs which far outweigh its apparent savings. As payment systems continue to place pressure on operating margins, it becomes even more critical that both academic and community radiation oncology practices know the cost of providing services.
78 FR 12040 - Proposed Information Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-21
... CORPORATION FOR NATIONAL AND COMMUNITY SERVICE Proposed Information Collection; Comment Request... with an opportunity to comment on proposed and/or continuing collections of information in accordance... Minnesota Reading [[Page 12041
40 CFR 57.810 - Filing of briefs, proposed findings, and proposed recommendations.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Filing of briefs, proposed findings, and proposed recommendations. 57.810 Section 57.810 Protection of Environment ENVIRONMENTAL PROTECTION... Requirement for Use of Continuous Emission Reduction Technology § 57.810 Filing of briefs, proposed findings...
Gamma ray astrophysics to the year 2000. Report of the NASA Gamma Ray Program Working Group
NASA Technical Reports Server (NTRS)
1988-01-01
Important developments in gamma-ray astrophysics up to energies of 100 GeV during the last decade are reviewed. Also, the report seeks to define the major current scientific goals of the field and proposes a vigorous program to pursue them, extending to the year 2000. The goals of gamma-ray astronomy include the study of gamma rays which provide the most direct means of studying many important problems in high energy astrophysics including explosive nucleosynthesis, accelerated particle interactions and sources, and high-energy processes around compact objects. The current research program in gamma-ray astronomy in the U.S. including the space program, balloon program and foreign programs in gamma-ray astronomy is described. The high priority recommendations for future study include an Explorer-class high resolution gamma-ray spectroscopy mission and a Get Away Special cannister (GAS-can) or Scout class multiwavelength experiment for the study of gamma-ray bursts. Continuing programs include an extended Gamma Ray Observatory mission, continuation of the vigorous program of balloon observations of the nearby Supernova 1987A, augmentation of the balloon program to provide for new instruments and rapid scientific results, and continuation of support for theoretical research. Long term recommendations include new space missions using advanced detectors to better study gamma-ray sources, the development of these detectors, continued study for the assembly of large detectors in space, collaboration with the gamma-ray astronomy missions initiated by other countries, and consideration of the Space Station attached payloads for gamma-ray experiments.
The impact of buffer strips and stream-side grazing on small mammals in southwestern Wisconsin
Chapman, Erik W.; Ribic, C.A.
2002-01-01
The practice of continuously grazing cattle along streams has caused extensive degradation of riparian habitats. Buffer strips and managed intensive rotational grazing (MIRG) have been proposed to protect and restore stream ecosystems in Wisconsin. However, the ecological implications of a switch from traditional livestock management to MIRG or buffer strip establishment have not been investigated. Differences in small mammal communities associated with riparian areas on continuously grazed and MIRG pastures, as well as vegetative buffer strips adjacent to row crops, were investigated in southwestern Wisconsin during May-September 1997 and 1998. More species (mean of 6-7) were found on the buffer sites than on the pasture sites (mean of 2-5). Total small mammal abundance on buffer sites was greater than on the pastures as well: there were 3-5 times as many animals on the buffer sites compared to the pasture sites, depending on year. There were no differences in species richness or total abundance between MIRG and continuously grazed pastures in either year. Total small mammal abundance was greater near the stream than away from the stream, regardless of farm management practice but there were no differences in species richness. Buffer strips appear to support a particularly rich and abundant small mammal community. Although results did not detect a difference in small mammal use between pasture types, farm-wide implications of a conversion from continuous to MIRG styles of grazing may benefit small mammals indirectly by causing an increase in the prevalence of pasture in the agricultural landscape.
Huang, Yu-An; You, Zhu-Hong; Chen, Xing; Yan, Gui-Ying
2016-12-23
Protein-protein interactions (PPIs) are essential to most biological processes. Since bioscience has entered into the era of genome and proteome, there is a growing demand for the knowledge about PPI network. High-throughput biological technologies can be used to identify new PPIs, but they are expensive, time-consuming, and tedious. Therefore, computational methods for predicting PPIs have an important role. For the past years, an increasing number of computational methods such as protein structure-based approaches have been proposed for predicting PPIs. The major limitation in principle of these methods lies in the prior information of the protein to infer PPIs. Therefore, it is of much significance to develop computational methods which only use the information of protein amino acids sequence. Here, we report a highly efficient approach for predicting PPIs. The main improvements come from the use of a novel protein sequence representation by combining continuous wavelet descriptor and Chou's pseudo amino acid composition (PseAAC), and from adopting weighted sparse representation based classifier (WSRC). This method, cross-validated on the PPIs datasets of Saccharomyces cerevisiae, Human and H. pylori, achieves an excellent results with accuracies as high as 92.50%, 95.54% and 84.28% respectively, significantly better than previously proposed methods. Extensive experiments are performed to compare the proposed method with state-of-the-art Support Vector Machine (SVM) classifier. The outstanding results yield by our model that the proposed feature extraction method combing two kinds of descriptors have strong expression ability and are expected to provide comprehensive and effective information for machine learning-based classification models. In addition, the prediction performance in the comparison experiments shows the well cooperation between the combined feature and WSRC. Thus, the proposed method is a very efficient method to predict PPIs and may be a useful supplementary tool for future proteomics studies.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-26
... (Business Continuity and Contingency Plans) and adopt new Rule 4370--NYSE Amex Equities (Business Continuity... Continuity and Contingency Plans) as substantively duplicative of NASD Rules 3510 (Business Continuity Plans... Equities (Business Continuity and Contingency Plans) to remove the existing text and incorporate NASD Rules...
Usability, Quality, Value and E-Learning Continuance Decisions
ERIC Educational Resources Information Center
Chiu, Chao-Min; Hsu, Meng-Hsiang; Sun, Szu-Yuan; Lin, Tung-Ching; Sun, Pei-Chen
2005-01-01
Previous research suggests that an eventual information technology (IT) success depend on both its initial adoption (acceptance) and subsequent continued usage (continuance). Expectancy disconfirmation theory (EDT) has been successfully used to predict users' intention to continue using information technologies. This study proposed a decomposed…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-06
... NATIONAL SCIENCE FOUNDATION Proposed Collection of Information; Comment Request: Biological Sciences Proposal Classification Form AGENCY: National Science Foundation. ACTION: Notice. SUMMARY: The... Biological Sciences has a continuing commitment to monitor its information collection in order to preserve...
49 CFR 845.27 - Proposed findings.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 7 2010-10-01 2010-10-01 false Proposed findings. 845.27 Section 845.27 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL TRANSPORTATION SAFETY BOARD... Proposed findings. Any party may submit proposed findings to be drawn from the testimony and exhibits, a...
Laboratory Directed Research and Development 1998 Annual Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pam Hughes; Sheila Bennett eds.
1999-07-14
The Laboratory's Directed Research and Development (LDRD) program encourages the advancement of science and the development of major new technical capabilities from which future research and development will grow. Through LDRD funding, Pacific Northwest continually replenishes its inventory of ideas that have the potential to address major national needs. The LDRD program has enabled the Laboratory to bring to bear its scientific and technical capabilities on all of DOE's missions, particularly in the arena of environmental problems. Many of the concepts related to environmental cleanup originally developed with LDRD funds are now receiving programmatic support from DOE, LDRD-funded work inmore » atmospheric sciences is now being applied to DOE's Atmospheric Radiation Measurement Program. We also have used concepts initially explored through LDRD to develop several winning proposals in the Environmental Management Science Program. The success of our LDRD program is founded on good management practices that ensure funding is allocated and projects are conducted in compliance with DOE requirements. We thoroughly evaluate the LDRD proposals based on their scientific and technical merit, as well as their relevance to DOE's programmatic needs. After a proposal is funded, we assess progress annually using external peer reviews. This year, as in years past, the LDRD program has once again proven to be the major enabling vehicle for our staff to formulate new ideas, advance scientific capability, and develop potential applications for DOE's most significant challenges.« less
Exploring the Full Range of Properties of Quasar Spectral Distributions
NASA Technical Reports Server (NTRS)
Wilkes, B.
1998-01-01
The aim of this work is to support our ISO, far-infrared (IR) observing program of quasars and active galaxies. We have obtained, as far as possible, complete spectral energy distributions (radio-X-ray) of the ISO sample in order to fully delineate the continuum shapes and to allow detailed modelling of that continuum. This includes: ground-based optical, near-IR and mm data, the spectral ranges closest to the ISO data, within 1-2 years of the ISO observations themselves. ISO was launched in Nov 1995 and is currently observing routinely. It has an estimated lifetime is 2 years. All near-IR and optical imaging and spectroscopy are now in hand and in the process of being reduced, mm data collection and proposal writing continues.
Advanced Global Atmospheric Gases Experiment (AGAGE)
NASA Technical Reports Server (NTRS)
Prinn, Ronald G.; Kurylo, Michael (Technical Monitor)
2004-01-01
We seek funding from NASA for the third year (2005) of the four-year period January 1, 2003 - December 31, 2006 for continued support of the MIT contributions to the multi-national global atmospheric trace species measurement program entitled Advanced Global Atmospheric Gases Experiment (AGAGE). The case for real-time high-frequency measurement networks like AGAGE is very strong and the observations and their interpretation are widely recognized for their importance to ozone depletion and climate change studies and to verification issues arising from the Montreal Protocol (ozone) and Kyoto Protocol (climate). The proposed AGAGE program is distinguished by its capability to measure over the globe at high frequency almost all of the important species in the Montreal Protocol and almost all of the significant non-CO2 gases in the Kyoto Protocol.
Biobjective planning of an active debris removal mission
NASA Astrophysics Data System (ADS)
Madakat, Dalal; Morio, Jérôme; Vanderpooten, Daniel
2013-03-01
The growth of the orbital debris population has been a concern to the international space community for several years. Recent studies have shown that the debris environment in Low Earth Orbit (LEO, defined as the region up to 2000 km altitude) has reached a point where the debris population will continue to increase even if all future launches are suspended. As the orbits of these objects often overlap the trajectories of satellites, debris create a potential collision risk. However, several studies show that about 5 objects per year should be removed in order to keep the future LEO environment stable. In this article, we propose a biobjective time dependent traveling salesman problem (BiTDTSP) model for the problem of optimally removing debris and use a branch and bound approach to deal with it.
NASA Astrophysics Data System (ADS)
Kazakis, Nikolaos A.
2018-01-01
The present comment concerns the correct presentation of an algorithm proposed in the above paper for the glow-curve deconvolution in the case of continuous distribution of trapping states. Since most researchers would use directly the proposed algorithm as published, they should be notified of its correct formulation during the fitting of TL glow curves of materials with continuous trap distribution using this Equation.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Weisbin, C.R.
1987-03-01
This document reviews research accomplishments achieved by the staff of the Center for Engineering Systems Advanced Research (CESAR) during the fiscal years 1984 through 1987. The manuscript also describes future CESAR objectives for the 1988-1991 planning horizon, and beyond. As much as possible, the basic research goals are derived from perceived Department of Energy (DOE) needs for increased safety, productivity, and competitiveness in the United States energy producing and consuming facilities. Research areas covered include the HERMIES-II Robot, autonomous robot navigation, hypercube computers, machine vision, and manipulators.
No longer simply a Practice-based Research Network (PBRN) health improvement networks.
Williams, Robert L; Rhyne, Robert L
2011-01-01
While primary care Practice-based Research Networks are best known for their original, research purpose, evidence accumulating over the last several years is demonstrating broader values of these collaborations. Studies have demonstrated their role in quality improvement and practice change, in continuing professional education, in clinician retention in medically underserved areas, and in facilitating transition of primary care organization. A role in informing and facilitating health policy development is also suggested. Taking into account this more robust potential, we propose a new title, the Health Improvement Network, and a new vision for Practice-based Research Networks.
Role of Ionizing Radiation in Neurodegenerative Diseases
Sharma, Neel K.; Sharma, Rupali; Mathur, Deepali; Sharad, Shashwat; Minhas, Gillipsie; Bhatia, Kulsajan; Anand, Akshay; Ghosh, Sanchita P.
2018-01-01
Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, whereas chronic effects may persist for a number of years. Radiation can increase many circulatory, age related and neurodegenerative diseases. Neurodegenerative diseases occur a long time after exposure to radiation, as demonstrated in atomic bomb survivors, and are still controversial. This review discuss the role of IR in neurodegenerative diseases and proposes an association between neurodegenerative diseases and exposure to IR. PMID:29867445
Investigating La Réunion Hot Spot From Crust to Core
NASA Astrophysics Data System (ADS)
Barruol, Guilhem; Sigloch, Karin
2013-06-01
Whether volcanic intraplate hot spots are underlain by deep mantle plumes continues to be debated 40 years after the hypothesis was proposed by Morgan [1972]. Arrivals of buoyant plume heads may have been among the most disruptive agents in Earth's history, initiating continental breakup, altering global climate, and triggering mass extinctions. Further, with the temporary shutdown of European air traffic in 2010 caused by the eruption of Eyjafjallajökull, a geologically routine eruption in the tail end of the presumed Iceland plume, the world witnessed an intrusion of hot spot activity into modern-day life.
77 FR 13076 - Proposed Information Collection; Comment Request; Quarterly Services Survey
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-05
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)).
A 0.4-2.3 GHz broadband power amplifier extended continuous class-F design technology
NASA Astrophysics Data System (ADS)
Chen, Peng; He, Songbai
2015-08-01
A 0.4-2.3 GHz broadband power amplifier (PA) extended continuous class-F design technology is proposed in this paper. Traditional continuous class-F PA performs in high-efficiency only in one octave bandwidth. With the increasing development of wireless communication, the PA is in demand to cover the mainstream communication standards' working frequencies from 0.4 GHz to 2.2 GHz. In order to achieve this objective, the bandwidths of class-F and continuous class-F PA are analysed and discussed by Fourier series. Also, two criteria, which could reduce the continuous class-F PA's implementation complexity, are presented and explained to investigate the overlapping area of the transistor's current and voltage waveforms. The proposed PA design technology is based on the continuous class-F design method and divides the bandwidth into two parts: the first part covers the bandwidth from 1.3 GHz to 2.3 GHz, where the impedances are designed by the continuous class-F method; the other part covers the bandwidth from 0.4 GHz to 1.3 GHz, where the impedance to guarantee PA to be in high-efficiency over this bandwidth is selected and controlled. The improved particle swarm optimisation is employed for realising the multi-impedances of output and input network. A PA based on a commercial 10 W GaN high electron mobility transistor is designed and fabricated to verify the proposed design method. The simulation and measurement results show that the proposed PA could deliver 40-76% power added efficiency and more than 11 dB power gain with more than 40 dBm output power over the bandwidth from 0.4-2.3 GHz.
Continuing Development of a Hybrid Model (VSH) of the Neutral Thermosphere
NASA Technical Reports Server (NTRS)
Burns, Alan
1996-01-01
We propose to continue the development of a new operational model of neutral thermospheric density, composition, temperatures and winds to improve current engineering environment definitions of the neutral thermosphere. This model will be based on simulations made with the National Center for Atmospheric Research (NCAR) Thermosphere-Ionosphere- Electrodynamic General Circulation Model (TIEGCM) and on empirical data. It will be capable of using real-time geophysical indices or data from ground-based and satellite inputs and provides neutral variables at specified locations and times. This "hybrid" model will be based on a Vector Spherical Harmonic (VSH) analysis technique developed (over the last 8 years) at the University of Michigan that permits the incorporation of the TIGCM outputs and data into the model. The VSH model will be a more accurate version of existing models of the neutral thermospheric, and will thus improve density specification for satellites flying in low Earth orbit (LEO).
NASA Technical Reports Server (NTRS)
Bowen, Brent; Fink, Mary; Gogos, George; Moussavi, Massoum; Nickerson, Jocelyn; Rundquist, Donald; Russell, Valerie; Tarry, Scott
2004-01-01
The Aeronautics Education, Research, and Industry Alliance (AERIAL), which began as a comprehensive, multi-faceted NASA EPSCoR 2000 initiative, has contributed substantially to the strategic research and technology priorities of NASA, while intensifying Nebraska's rapidly growing aeronautics research and development endeavors. AERIAL has enabled Nebraska researchers to: (a) continue strengthening their collaborative relationships with NASA Field Centers, Codes, and Enterprises; (b) increase the capacity of higher education throughout Nebraska to invigorate and expand aeronautics research; and (c) expedite the development of aeronautics-related research infrastructure and industry in the state. Nebraska has placed emphasis on successfully securing additional funds from non-EPSCoR and non-NASA sources. AERIAL researchers have aggressively pursued additional funding opportunities offered by NASA, industry, and other agencies. This report contains a summary of AERIAL's activities and accomplishments during its first three years of implementation.
Payload advisory panel recommendations
NASA Technical Reports Server (NTRS)
Moore, Berrien, III
1991-01-01
The Payload Advisory Panel proposes a restructured Earth Observing System (EOS) mission to address high-priority science and environmental policy issues in Earth System Science. These issues have been identified through studies conducted by the Intergovernmental Panel on Climate Change (IPCC), the United States Environmental Protection Agency (EPA), and the Committee on Earth and Environmental Sciences (CEES). The restructured EOS defers efforts to improve the understanding of the middle and upper stratosphere and solid earth geophysics. The strategy of the mission combines high priority new measurements with continuation of critical data sets begun by missions which precede EOS. Collaborative arrangements with international partners are an essential part of the program and additional arrangements are posed. The need for continuity in Earth observations and the urgency of environmental questions require launch of some EOS elements as soon as possible. They further require maintenance of the EOS objective of obtaining consistent 15-year measurement records.
Payload advisory panel recommendations
NASA Astrophysics Data System (ADS)
Moore, Berrien, III
1991-11-01
The Payload Advisory Panel proposes a restructured Earth Observing System (EOS) mission to address high-priority science and environmental policy issues in Earth System Science. These issues have been identified through studies conducted by the Intergovernmental Panel on Climate Change (IPCC), the United States Environmental Protection Agency (EPA), and the Committee on Earth and Environmental Sciences (CEES). The restructured EOS defers efforts to improve the understanding of the middle and upper stratosphere and solid earth geophysics. The strategy of the mission combines high priority new measurements with continuation of critical data sets begun by missions which precede EOS. Collaborative arrangements with international partners are an essential part of the program and additional arrangements are posed. The need for continuity in Earth observations and the urgency of environmental questions require launch of some EOS elements as soon as possible. They further require maintenance of the EOS objective of obtaining consistent 15-year measurement records.
Navarro, Roberto Campos; Sánchez, Edith Yesenia Peña; Maya, Alfredo Paulo
2017-01-01
Over the last 26 years, the Mexican government has developed a number of activities and discourses around what has been called "intercultural health," directed especially at indigenous peoples in Mexico (some 62, according to linguistic criteria). In this way, the government has built health care institutions (rural centers, clinics, and hospitals) in states like Puebla, Nayarit, Oaxaca, Chiapas, Queretaro, and Jalisco, proposing the implementation of cultural pertinence indicators (which are minimal and inadequate). Nevertheless, the health conditions among indigenous populations and the quality of health care provided by public institutions continue to be precarious in terms of human and material resources (health personnel, drugs, etc.) and discriminatory with respect to the form and content of the provided services. This paper describes some of the governmental interventions that purport to be institutional improvements in the field of interculturality, but that actually represent the continuity of arbitrary and exclusive policies.
With or without rafts? Alternative views on cell membranes.
Sevcsik, Eva; Schütz, Gerhard J
2016-02-01
The fundamental mechanisms of protein and lipid organization at the plasma membrane have continued to engage researchers for decades. Among proposed models, one idea has been particularly successful which assumes that sterol-dependent nanoscopic phases of different lipid chain order compartmentalize proteins, thereby modulating protein functionality. This model of membrane rafts has sustainably sparked the fields of membrane biophysics and biology, and shifted membrane lipids into the spotlight of research; by now, rafts have become an integral part of our terminology to describe a variety of cell biological processes. But is the evidence clear enough to continue supporting a theoretical concept which has resisted direct proof by observation for nearly twenty years? In this essay, we revisit findings that gave rise to and substantiated the raft hypothesis, discuss its impact on recent studies, and present alternative mechanisms to account for plasma membrane heterogeneity. © 2015 WILEY Periodicals, Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-30
... http://www.msha.gov/REGS/FEDREG/PROPOSED/2010PROP/2010-25249.pdf . The proposed rule would revise the.../PROPOSED/2010PROP/2010-25249.pdf . The following error in the preamble to the proposed rule is corrected to...
7 CFR 3403.10 - Proposal review.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 15 2014-01-01 2014-01-01 false Proposal review. 3403.10 Section 3403.10 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Submission and Evaluation of Proposals § 3403.10 Proposal...
7 CFR 3403.10 - Proposal review.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 15 2013-01-01 2013-01-01 false Proposal review. 3403.10 Section 3403.10 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Submission and Evaluation of Proposals § 3403.10 Proposal...
7 CFR 3403.10 - Proposal review.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 15 2012-01-01 2012-01-01 false Proposal review. 3403.10 Section 3403.10 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Submission and Evaluation of Proposals § 3403.10 Proposal...
A preferred provider organization (PPO) case study for mental health and substance abuse.
Gomillion, I; Self, D R
1988-01-01
The Preferred Provider Organization concept is quickly becoming more popular because of its relative cost-effectiveness and recent successes. Managed care through means of this mental health and substance abuse PPO may well serve as the prototype for the general health care cost containment efforts of the future for the self-insured insurance plans for Alabama state employees and teachers. The first year also revealed several problems in the original proposal especially with respect to the unintended attractiveness of inpatient/residential care. Consequently, copayment plans were added to dissuade unnecessary lengthy stays (see Table 2). Second, a new quality assurance mechanism has been added to further evaluate the need for admissions to facilities, as well as for the need for continued inpatient treatment. The Alabama Quality Assurance Foundation (AQAF) began on January 1, 1988, conducting the preadmission certification on all admissions based upon criteria established jointly by AQAF and the PPO providers. In addition, AQAF will conduct continuing stay reviews at predetermined time periods to ensure that continued treatment in an inpatient setting is indeed necessary.
Deng, Yun; Hou, Jinghui; Ma, Xiao; Cai, Shuqin
2013-05-01
Online entertainment communities have exploded in popularity and drawn attention from researchers. However, few studies have investigated what leads people to remain active in such communities at the postadoption stage. We proposed and tested a dual model of entertainment-based and community-based mechanisms to examine the factors that affect individuals' continued participation in online entertainment communities. Survival analysis was employed on a longitudinal dataset of 2,302 users collected over 2 years from an online game community. Our results were highly consistent with the theoretical model. Specifically, under the entertainment-based mechanism, our findings showed that the intensities of initial use and frequent use were positive predictors of players' activity lifespan. Under the community-based mechanism, the results demonstrated that the number of guilds a player was affiliated with and the average number of days of being a guild member positively predict players' lifespan in the game. Overall, our study suggests that the entertainment-based mechanism and community-based mechanism are two key drivers that determinate individuals' continued participation in online entertainment communities.
Flexible and Transparent User Authentication for Mobile Devices
NASA Astrophysics Data System (ADS)
Clarke, Nathan; Karatzouni, Sevasti; Furnell, Steven
The mobile device has become a ubiquitous technology that is capable of supporting an increasingly large array of services, applications and information. Given their increasing importance, it is imperative to ensure that such devices are not misused or abused. Unfortunately, a key enabling control to prevent this, user authentication, has not kept up with the advances in device technology. This paper presents the outcomes of a 2 year study that proposes the use of transparent and continuous biometric authentication of the user: providing more comprehensive identity verification; minimizing user inconvenience; and providing security throughout the period of use. A Non-Intrusive and Continuous Authentication (NICA) system is described that maintains a continuous measure of confidence in the identity of the user, removing access to sensitive services and information with low confidence levels and providing automatic access with higher confidence levels. An evaluation of the framework is undertaken from an end-user perspective via a trial involving 27 participants. Whilst the findings raise concerns over education, privacy and intrusiveness, overall 92% of users felt the system offered a more secure environment when compared to existing forms of authentication.
Intergenerational Continuity in Parenting Behavior: Mediating Pathways and Child Effects
Neppl, Tricia K.; Conger, Rand D.; Scaramella, Laura V.; Ontai, Lenna L.
2009-01-01
This prospective, longitudinal investigation examined mechanisms proposed to explain continuities in parenting behavior across two generations (G1, G2). Data came from 187 G2 adults, their mothers (G1), and their children (G3). Prospective information regarding G2 was collected both during adolescence and early adulthood. G1 data were collected during G2’s adolescence and G3 data were generated during the preschool years. Assessments included both observational and self-report measures. The results indicated a direct relationship between G1 and G2 harsh parenting and between G1 and G2 positive parenting. As predicted, specific mediators accounted for intergenerational continuity in particular types of parenting behavior. G2 externalizing behavior mediated the relationship between G1 and G2 harsh parenting, while G2 academic attainment mediated the relationship between G1 and G2 positive parenting. In addition, the hypothesized mediating pathways remained statistically significant after taking into account possible G2 effects on G1 parenting and G3 effects on G2 parenting. PMID:19702389
LSPECS: A Proposed Robotic Astronomy Mission to the Lunar South Polar Regions
NASA Technical Reports Server (NTRS)
Lowman, Paul D., Jr.
2003-01-01
This paper outlines a possible mission to emplace a robotic infrared/submillimeter wave interferometer array near the lunar south pole. This region has now been investigated by the Clementine and Lunar Prospector missions, and by Earth-based radar, and its topography and thermal environment are fairly well-known. The area would be exceptionally suitable for infrared/submillimeter astronomy because of the continually low temperatures, approaching that of liquid nitrogen (77K) in some places. The presence of ice has been inferred independently from Clementine and Lunar Prospector, providing another incentive for a south polar mission. A submillimeter spaceborne interferometer mission, Submillimeter Probe of the Evolution of the Cosmic Structure (SPECS) has been proposed by John Mather and others, covering the 40 - 500 micron region with 3 formation flying telescopes. The present paper proposes a lunar adaptation of the SPECS concept, LSPECS. This adaptation would involve landing 4 telescopes on the area north of Shackleton crater at zero degrees longitude. This is in nearly year round darkness but is continually radar visible from Earth. The landed payload of LSPECS would include a telerobotic rover, 4 three meter submm telescopes, a solar power array to be emplaced on the continually sunlit north rim of Shackleton crater, and an S-band antenna for data relay to Earth. Operation without the use of expendable cryogenics for cooling might be possible, trading long exposure time for instrument temperatures above that of liquid helium. The LSPECS would permit long-term study of an extremely wide range of cosmic and solar system phenomena in the southern celestial hemisphere. For complete sky coverage, a similar installation near the north pole would be required. The LSPECS site would also be suitable other types of observation, such as optical interferometry or centimeter wavelength radio astronomy. The lunar south pole is also of great interest because of its extensive ice deposits, which may represent cometary infall with pre-biotic compounds.
Training Pathology Residents to Practice 21st Century Medicine: A Proposal.
Black-Schaffer, W Stephen; Morrow, Jon S; Prystowsky, Michael B; Steinberg, Jacob J
2016-01-01
Scientific advances, open information access, and evolving health-care economics are disrupting extant models of health-care delivery. Physicians increasingly practice as team members, accountable to payers and patients, with improved efficiency, value, and quality. This change along with a greater focus on population health affects how systems of care are structured and delivered. Pathologists are not immune to these disruptors and, in fact, may be one of the most affected medical specialties. In the coming decades, it is likely that the number of practicing pathologists will decline, requiring each pathologist to serve more and often sicker patients. The demand for increasingly sophisticated yet broader diagnostic skills will continue to grow. This will require pathologists to acquire appropriate professional training and interpersonal skills. Today's pathology training programs are ill designed to prepare such practitioners. The time to practice for most pathology trainees is typically 5 to 6 years. Yet, trainees often lack sufficient experience to practice independently and effectively. Many studies have recognized these challenges suggesting that more effective training for this new century can be implemented. Building on the strengths of existing programs, we propose a redesign of pathology residency training that will meet (and encourage) a continuing evolution of American Board of Pathology and Accreditation Council for Graduate Medical Education requirements, reduce the time to readiness for practice, and produce more effective, interactive, and adaptable pathologists. The essence of this new model is clear definition and acquisition of core knowledge and practice skills that span the anatomic and clinical pathology continuum during the first 2 years, assessed by competency-based metrics with emphasis on critical thinking and skill acquisition, followed by individualized modular training with intensively progressive responsibility during the final years of training. We anticipate that implementing some or all aspects of this model will enable residents to attain a higher level of competency within the current time-based constraints of residency training.
Rockers, Peter C; Tugwell, Peter; Røttingen, John-Arne; Bärnighausen, Till
2017-09-01
Although the number of quasi-experiments conducted by health researchers has increased in recent years, there clearly remains unrealized potential for using these methods for causal evaluation of health policies and programs globally. This article proposes five prescriptions for capturing the full value of quasi-experiments for health research. First, new funding opportunities targeting proposals that use quasi-experimental methods should be made available to a broad pool of health researchers. Second, administrative data from health programs, often amenable to quasi-experimental analysis, should be made more accessible to researchers. Third, training in quasi-experimental methods should be integrated into existing health science graduate programs to increase global capacity to use these methods. Fourth, clear guidelines for primary research and synthesis of evidence from quasi-experiments should be developed. Fifth, strategic investments should be made to continue to develop new innovations in quasi-experimental methodologies. Tremendous opportunities exist to expand the use of quasi-experimental methods to increase our understanding of which health programs and policies work and which do not. Health researchers should continue to expand their commitment to rigorous causal evaluation with quasi-experimental methods, and international institutions should increase their support for these efforts. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Christoudias, T.; Proestos, Y.; Lelieveld, J.
2014-05-01
We estimate the global risk from the release and atmospheric dispersion of radionuclides from nuclear power plant accidents using the EMAC atmospheric chemistry-general circulation model. We included all nuclear reactors that are currently operational, under construction and planned or proposed. We implemented constant continuous emissions from each location in the model and simulated atmospheric transport and removal via dry and wet deposition processes over 20 years (2010-2030), driven by boundary conditions based on the IPCC A2 future emissions scenario. We present global overall and seasonal risk maps for potential surface layer concentrations and ground deposition of radionuclides, and estimate potential doses to humans from inhalation and ground-deposition exposures to radionuclides. We find that the risk of harmful doses due to inhalation is typically highest in the Northern Hemisphere during boreal winter, due to relatively shallow boundary layer development and limited mixing. Based on the continued operation of the current nuclear power plants, we calculate that the risk of radioactive contamination to the citizens of the USA will remain to be highest worldwide, followed by India and France. By including stations under construction and those that are planned and proposed, our results suggest that the risk will become highest in China, followed by India and the USA.
NASA Astrophysics Data System (ADS)
Christoudias, T.; Proestos, Y.; Lelieveld, J.
2014-12-01
We estimate the global risk from the release and atmospheric dispersion of radionuclides from nuclear power plant accidents using the EMAC atmospheric chemistry-general circulation model. We included all nuclear reactors that are currently operational, under construction and planned or proposed. We implemented constant continuous emissions from each location in the model and simulated atmospheric transport and removal via dry and wet deposition processes over 20 years (2010-2030), driven by boundary conditions based on the IPCC A2 future emissions scenario. We present global overall and seasonal risk maps for potential surface layer concentrations and ground deposition of radionuclides, and estimate potential doses to humans from inhalation and ground-deposition exposures to radionuclides. We find that the risk of harmful doses due to inhalation is typically highest in the Northern Hemisphere during boreal winter, due to relatively shallow boundary layer development and limited mixing. Based on the continued operation of the current nuclear power plants, we calculate that the risk of radioactive contamination to the citizens of the USA will remain to be highest worldwide, followed by India and France. By including stations under construction and those that are planned and proposed, our results suggest that the risk will become highest in China, followed by India and the USA.
Automating the self-scheduling process of nurses in Swedish healthcare: a pilot study.
Rönnberg, Elina; Larsson, Torbjörn
2010-03-01
Hospital wards need to be staffed by nurses round the clock, resulting in irregular working hours for many nurses. Over the years, the nurses' influence on the scheduling has been increased in order to improve their working conditions. In Sweden it is common to apply a kind of self-scheduling where each nurse individually proposes a schedule, and then the final schedule is determined through informal negotiations between the nurses. This kind of self-scheduling is very time-consuming and does often lead to conflicts. We present a pilot study which aims at determining if it is possible to create an optimisation tool that automatically delivers a usable schedule based on the schedules proposed by the nurses. The study is performed at a typical Swedish nursing ward, for which we have developed a mathematical model and delivered schedules. The results of this study are very promising and suggest continued work along these lines.
Improved color constancy in honey bees enabled by parallel visual projections from dorsal ocelli.
Garcia, Jair E; Hung, Yu-Shan; Greentree, Andrew D; Rosa, Marcello G P; Endler, John A; Dyer, Adrian G
2017-07-18
How can a pollinator, like the honey bee, perceive the same colors on visited flowers, despite continuous and rapid changes in ambient illumination and background color? A hundred years ago, von Kries proposed an elegant solution to this problem, color constancy, which is currently incorporated in many imaging and technological applications. However, empirical evidence on how this method can operate on animal brains remains tenuous. Our mathematical modeling proposes that the observed spectral tuning of simple ocellar photoreceptors in the honey bee allows for the necessary input for an optimal color constancy solution to most natural light environments. The model is fully supported by our detailed description of a neural pathway allowing for the integration of signals originating from the ocellar photoreceptors to the information processing regions in the bee brain. These findings reveal a neural implementation to the classic color constancy problem that can be easily translated into artificial color imaging systems.
Artificial immune system via Euclidean Distance Minimization for anomaly detection in bearings
NASA Astrophysics Data System (ADS)
Montechiesi, L.; Cocconcelli, M.; Rubini, R.
2016-08-01
In recent years new diagnostics methodologies have emerged, with particular interest into machinery operating in non-stationary conditions. In fact continuous speed changes and variable loads make non-trivial the spectrum analysis. A variable speed means a variable characteristic fault frequency related to the damage that is no more recognizable in the spectrum. To overcome this problem the scientific community proposed different approaches listed in two main categories: model-based approaches and expert systems. In this context the paper aims to present a simple expert system derived from the mechanisms of the immune system called Euclidean Distance Minimization, and its application in a real case of bearing faults recognition. The proposed method is a simplification of the original process, adapted by the class of Artificial Immune Systems, which proved to be useful and promising in different application fields. Comparative results are provided, with a complete explanation of the algorithm and its functioning aspects.
An all-electric single-molecule motor.
Seldenthuis, Johannes S; Prins, Ferry; Thijssen, Joseph M; van der Zant, Herre S J
2010-11-23
Many types of molecular motors have been proposed and synthesized in recent years, displaying different kinds of motion, and fueled by different driving forces such as light, heat, or chemical reactions. We propose a new type of molecular motor based on electric field actuation and electric current detection of the rotational motion of a molecular dipole embedded in a three-terminal single-molecule device. The key aspect of this all-electronic design is the conjugated backbone of the molecule, which simultaneously provides the potential landscape of the rotor orientation and a real-time measure of that orientation through the modulation of the conductivity. Using quantum chemistry calculations, we show that this approach provides full control over the speed and continuity of motion, thereby combining electrical and mechanical control at the molecular level over a wide range of temperatures. Moreover, chemistry can be used to change all key parameters of the device, enabling a variety of new experiments on molecular motors.
The Case for a Smoker's License
Chapman, Simon
2012-01-01
Background to the debate Tobacco continues to kill millions of people around the world each year and its use is increasing in some countries, which makes the need for new, creative, and radical efforts to achieve the tobacco control endgame vitally important. One such effort is discussed in this PLOS Medicine Debate, where Simon Chapman presents his proposal for a “smoker's license” and Jeff Collin argues against. Chapman sets out a case for introducing a smart card license for smokers designed to limit access to tobacco products and encourage cessation. Key elements of the smoker's license include smokers setting daily limits, financial incentives for permanent license surrender, and a test of health risk knowledge for commencing smokers. Collin argues against the proposal, saying that it would shift focus away from the real vector of the epidemic—the tobacco industry—and that by focusing on individuals it would censure victims, increase stigmatization of smokers, and marginalize the poor. PMID:23152726
76 FR 70075 - Proximity Detection Systems for Continuous Mining Machines in Underground Coal Mines
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-10
... Detection Systems for Continuous Mining Machines in Underground Coal Mines AGENCY: Mine Safety and Health... proposed rule addressing Proximity Detection Systems for Continuous Mining Machines in Underground Coal... Detection Systems for Continuous Mining Machines in Underground Coal Mines. MSHA conducted hearings on...
ERIC Educational Resources Information Center
Wilcock, Peter M.; Janes, Gillian; Chambers, Alison
2009-01-01
Health care improvement and continuing professional education must be better understood if we are to promote continuous service improvement through interprofessional learning in the workplace. We propose that situating interprofessional working, interprofessional learning, work-based learning, and service improvement within a framework of social…
Continuity Between DSM-5 Section II and III Personality Disorders in a Dutch Clinical Sample.
Orbons, Irene M J; Rossi, Gina; Verheul, Roel; Schoutrop, Mirjam J A; Derksen, Jan L L; Segal, Daniel L; van Alphen, Sebastiaan P J
2018-05-14
The goal of this study was to evaluate the continuity across the Section II personality disorders (PDs) and the proposed Section III model of PDs in the Diagnostic and Statistical Manual of Mental Disorders (5th ed. [DSM-5]; American Psychiatric Association, 2013a ). More specifically, we analyzed association between the DSM-5 Section III pathological trait facets and Section II PDs among 110 Dutch adults (M age = 35.8 years, range = 19-60 years) receiving mental health care. We administered the Structured Clinical Interview for DSM-IV Axis II Disorders to all participants. Participants also completed the self-report Personality Inventory for DSM-5 (PID-5) as a measure of pathological trait facets. The distributions underlying the dependent variable were modeled as criterion counts, using negative binomial regression. The results provided some support for the validity of the PID-5 and the DSM-5 Section III Alternative Model, although analyses did not show a perfect match. Both at the trait level and the domain level, analyses showed mixed evidence of significant relationships between the PID-5 trait facets and domains with the traditional DSM-IV PDs.
NASA Astrophysics Data System (ADS)
Palilingan, V. R.; Mario, T. P.
2018-01-01
Industry in Indonesia continues to grow from year to year. Along with these developments, the use of information technology, which is the basis of information systems, should be considered as a handy tool to survive in the competition in the industry. Various previous studies have discussed much the use of information systems and their role at the strategic level. But more in-depth research is still needed to find out the extent to which the maturity of the use of information systems through its elements can affect the performance of companies in various sectors industries in Indonesia. It is hoped that this concept can be used as a subsequent research by distributing questionnaires based on the method of statements that have been defined by researchers. With this concepts, the next development will continue to measure the relationship information systems maturity in general with the organizations performance. The result of the concept proposed by the researcher is expected to be able to measure the maturity relationship of an information system with the connection with the consumer, demand/supply planning element, innovation, performance measurement, IT impact management and also internal process.
Urban noise functional stratification for estimating average annual sound level.
Rey Gozalo, Guillermo; Barrigón Morillas, Juan Miguel; Prieto Gajardo, Carlos
2015-06-01
Road traffic noise causes many health problems and the deterioration of the quality of urban life; thus, adequate spatial noise and temporal assessment methods are required. Different methods have been proposed for the spatial evaluation of noise in cities, including the categorization method. Until now, this method has only been applied for the study of spatial variability with measurements taken over a week. In this work, continuous measurements of 1 year carried out in 21 different locations in Madrid (Spain), which has more than three million inhabitants, were analyzed. The annual average sound levels and the temporal variability were studied in the proposed categories. The results show that the three proposed categories highlight the spatial noise stratification of the studied city in each period of the day (day, evening, and night) and in the overall indicators (L(And), L(Aden), and L(A24)). Also, significant differences between the diurnal and nocturnal sound levels show functional stratification in these categories. Therefore, this functional stratification offers advantages from both spatial and temporal perspectives by reducing the sampling points and the measurement time.
Who Is a Cancer Survivor? A Systematic Review of Published Definitions.
Marzorati, Chiara; Riva, Silvia; Pravettoni, Gabriella
2017-06-01
The term "cancer survivor" is commonly used by different persons, clinical institutions, academic bodies, and political organizations although it lacks of a unanimous and detailed definition. The objective of the study is to make a systematic review of published and proposed definitions of "cancer survivor." Utilizing a systematic search strategy with different strings of "cancer survivor," we searched the following databases: Medline (June 1975-June 2015), Scopus (all the years), Web of Science (all the years), Google Scholar (all the years), ERIC (all the years). This review suggests that there is not a unique definition of who is a "cancer survivor" and what is "cancer survivorship." However, the most widely used definition sees cancer survivorship as a process that begins at the moment of diagnosis and continues through the balance of life. This definition highlights psychological and legal patient's needs-as well as medical ones-to receive care and assistance from the beginning and, at the same time, it establishes valid criteria for making scientific and statistical sampling research. The extensive use of the term "cancer survivor" indicates that it is a significant term. This review has been written to outline the state of the art and it invites to reflect on a shared definition that could satisfy both clinical and research aspects. Implication for cancer survivors: this compendium of proposed definitions may improve communication among the many patients and patient organizations that use and work with this term.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 22 2010-07-01 2010-07-01 false How can a person served by the public water system obtain EPA review of a State proposed small system variance? 142.310 Section 142.310 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-26
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)).
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-28
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)).
76 FR 32950 - Proposed Information Collection; Comment Request; 2012 Economic Census of Island Areas
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-07
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)).
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 23 2014-07-01 2014-07-01 false How can a person served by the public water system obtain EPA review of a State proposed small system variance? 142.310 Section 142.310 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-20
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)).
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-04
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)).
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-26
...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)).
Silva, Mauricio Rocha e
2011-01-01
OBJECTIVE: Impact Factors (IF) are widely used surrogates to evaluate single articles, in spite of known shortcomings imposed by cite distribution skewness. We quantify this asymmetry and propose a simple computer-based procedure for evaluating individual articles. METHOD: (a) Analysis of symmetry. Journals clustered around nine Impact Factor points were selected from the medical “Subject Categories” in Journal Citation Reports 2010. Citable items published in 2008 were retrieved and ranked by granted citations over the Jan/2008 - Jun/2011 period. Frequency distribution of cites, normalized cumulative cites and absolute cites/decile were determined for each journal cluster. (b) Positive Predictive Value. Three arbitrarily established evaluation classes were generated: LOW (1.3≤IF<2.6); MID: (2.6≤IF<3.9); HIGH: (IF≥3.9). Positive Predictive Value for journal clusters within each class range was estimated. (c) Continuously Variable Rating. An alternative evaluation procedure is proposed to allow the rating of individually published articles in comparison to all articles published in the same journal within the same year of publication. The general guiding lines for the construction of a totally dedicated software program are delineated. RESULTS AND CONCLUSIONS: Skewness followed the Pareto Distribution for (1
Development and Implementation of Degree Programs in Electric Drive Vehicle Technology
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ng, Simon
2013-09-30
The Electric-drive Vehicle Engineering (EVE) MS degree and graduate certificate programs have been continuing to make good progress, thanks to the funding and the guidance from DOE grant management group, the support from our University and College administrations, and to valuable inputs and feedback from our Industrial Advisory Board as well as our project partners Macomb Community College and NextEnergy. Table 1 below lists originally proposed Statement of Project Objectives (SOPO), which have all been completed successfully. Our program and course enrollments continue to be good and increasing, as shown in later sections. Our graduating students continue to get goodmore » job offers from local EV-related companies. Following the top recommendation from our Industrial Advisory Board, we were fortunate enough to be accepted into the prestigious EcoCAR2 (http://www.ecocar2.org/) North America university design competition, and have been having some modest success with the competition. But most importantly, EcoCAR2 offers the most holistic educational environment for integrating real-world engineering and design with our EVE graduate curriculum. Such integrations include true real-world hands-on course projects based on EcoCAR2 related tasks for the students, and faculty curricular and course improvements based on lessons and best practices learned from EcoCAR2. We are in the third and last year of EcoCAR2, and we have already formed a core group of students in pursuit of EcoCAR”3”, for which the proposal is due in early December.« less
49 CFR 389.15 - Contents of notices of proposed rule making.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 5 2010-10-01 2010-10-01 false Contents of notices of proposed rule making. 389.15 Section 389.15 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL... § 389.15 Contents of notices of proposed rule making. (a) Each notice of proposed rule making is...
49 CFR 389.15 - Contents of notices of proposed rule making.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 5 2011-10-01 2011-10-01 false Contents of notices of proposed rule making. 389.15 Section 389.15 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL... § 389.15 Contents of notices of proposed rule making. (a) Each notice of proposed rule making is...
Bajantri, Bharat; Lvovsky, Dmitry
2018-01-01
Obstructive sleep apnea syndrome is a disorder of sleep breathing that is a result of recurrent and intermittent hypoxia during sleep induced by the repeated partial or complete collapse of the upper airway, eventually causing chronic intermittent hypoxia. Non-alcoholic fatty liver disease is divided into non-alcoholic fatty liver and non-alcoholic steatohepatitis. Animal and human studies showed that obesity is associated with chronic liver hypoxia, even in the presence of systemic normoxia causing inflammation and release of cytokines. A “two-hit” model has been proposed. The first hit is characterized by insulin resistance and excess hepatic lipid accumulation secondary to abnormal fatty acid metabolism. Oxidative stress and inflammation are thought to comprise the second hit. Gold standard for the diagnosis of non-alcoholic steatohepatitis is a liver biopsy. Many clinical scores and non-invasive tools are used for the diagnosis of non-alcoholic steatohepatitis. Conservative management with lifestyle modifications including diet, exercise and weight loss remains the therapy of choice today. We present a case report of a 39-year-old man who was diagnosed with concomitant non-alcoholic steatohepatitis and severe obstructive sleep apnea. He was started treatment with continuous positive airway pressure and demonstrated excellent adherence to therapy for 6 years, with concomitant obstructive sleep apnea and non-alcoholic steatohepatitis which reversed with prolonged optimal continuous positive airway pressure therapy. Physical examination remained unremarkable except for morbid obesity. His abdominal girth, as well as body mass index, remained unchanged. After 6 years of optimal continuous positive airway pressure therapy, liver enzymes and relevant lipid panel normalized, suggesting reversal of non-alcoholic steatohepatitis. PMID:29915639
Continuity of care: an Italian clinical experience.
Tarquini, Roberto; Coletta, Davide; Mazzoccoli, Gianluigi; Gensini, Gian Franco
2013-10-01
Recently, there is a growing interest in the concept of "continuity of care," since patients, being older and more complex, are increasingly seen by an array of providers in a wide variety of organizations and places. Different models of continuity of care have been proposed, yet no single model of care coordination has been proven to be universally applicable across patient (and disease) populations. In the present paper, we introduce a novel model of continuity of care, the Ospedale Santa Verdiana, in Castelfiorentino (Tuscany, Italy), and its first period (1 year) of implementation, since January 2010. There are two main cornerstones: (a) the clinical and urgent need to bridge the gap between primary care and hospital care; and (b) the development and implementation of a model of continuity and coordination of care, which target the so-called complex patient. It is not specific for a single disease but it works "across diseases." There are three driving forces: (a) "primary care" since one of the two Hospital Coordinators is a primary care physician; (b) "hospital care" since patients in the decompensated phase often require hospitalization; and (c) the "University of Florence", which is the "glue". The duties of the Hospital Coordinator, who is an assistant professor at University of Florence, are to guarantee an efficacious and dynamic communication between primary care physicians and hospitalists, and by creating a school for practitioners of the continuity and coordination of care, to make this model exportable.
Li, Longyun; Wu, Xiaoli; Wang, Yu
2018-01-01
In this study, effects of continuous cropping on soil properties, enzyme activities, and relative abundance, community composition and diversity of fungal taxa were investigated. Rhizosphere soil from field continuously cropped for one-year, three-year and five-year by Coptis chinensis Franch. was collected and analyzed. Illumina high-throughput sequencing analysis showed that continuous cropping of C. chinensis resulted in a significant and continuous decline in the richness and diversity of soil fungal population. Ascomycota, Zygomycota, Basidiomycota, and Glomeromycota were the dominant phyla of fungi detected in rhizosphere soil. Fungal genera such as Phoma, Volutella, Pachycudonia, Heterodermia, Gibberella, Cladosporium, Trichocladium, and Sporothrix, were more dominant in continuously cropped samples for three-year and five-year compared to that for one-year. By contrast, genera, such as Zygosaccharomyces, Pseudotaeniolina, Hydnum, Umbelopsis, Humicola, Crustoderma, Psilocybe, Coralloidiomyces, Mortierella, Polyporus, Pyrenula, and Monographella showed higher relative abundance in one-year samples than that in three-year and five-year samples. Cluster analysis of the fungal communities from three samples of rhizosphere soil from C. chinensis field revealed that the fungal community composition, diversity, and structure were significantly affected by the continuous cropping. Continuous cropping of C. chinensis also led to significant declines in soil pH, urease, and catalase activities. Redundancy analysis showed that the soil pH had the most significant effect on soil fungal population under continuous cropping of C. chinensis. PMID:29538438
Song, Xuhong; Pan, Yuan; Li, Longyun; Wu, Xiaoli; Wang, Yu
2018-01-01
In this study, effects of continuous cropping on soil properties, enzyme activities, and relative abundance, community composition and diversity of fungal taxa were investigated. Rhizosphere soil from field continuously cropped for one-year, three-year and five-year by Coptis chinensis Franch. was collected and analyzed. Illumina high-throughput sequencing analysis showed that continuous cropping of C. chinensis resulted in a significant and continuous decline in the richness and diversity of soil fungal population. Ascomycota, Zygomycota, Basidiomycota, and Glomeromycota were the dominant phyla of fungi detected in rhizosphere soil. Fungal genera such as Phoma, Volutella, Pachycudonia, Heterodermia, Gibberella, Cladosporium, Trichocladium, and Sporothrix, were more dominant in continuously cropped samples for three-year and five-year compared to that for one-year. By contrast, genera, such as Zygosaccharomyces, Pseudotaeniolina, Hydnum, Umbelopsis, Humicola, Crustoderma, Psilocybe, Coralloidiomyces, Mortierella, Polyporus, Pyrenula, and Monographella showed higher relative abundance in one-year samples than that in three-year and five-year samples. Cluster analysis of the fungal communities from three samples of rhizosphere soil from C. chinensis field revealed that the fungal community composition, diversity, and structure were significantly affected by the continuous cropping. Continuous cropping of C. chinensis also led to significant declines in soil pH, urease, and catalase activities. Redundancy analysis showed that the soil pH had the most significant effect on soil fungal population under continuous cropping of C. chinensis.
NASA Astrophysics Data System (ADS)
Mufti Azis, Muhammad; Sudibyo, Hanifrahmawan; Budhijanto, Wiratni
2018-03-01
Indonesia is aiming to produce 30 million tones/year of crude palm oil (CPO) by 2020. As a result, 90 million tones/year of POME will be produced. POME is highly polluting wastewater which may cause severe environmental problem due to its high chemical oxygen demand (COD) and biochemical oxygen demand (BOD). Due to the limitation of open pond treatment, the use of AFBR has been considered as a potential technology to treat POME. This study aims to develop mathematical models of lab-sized Anaerobic Fluidized Bed Reactor (AFBR) in batch and continuous processes. In addition, the AFBR also utilized natural zeolite as an immobilized media for microbes. To initiate the biomass growth, biodiesel waste has been used as an inoculum. In the first part of this study, a batch AFBR was operated to evaluate the COD, VFA, and CH4 concentrations. By comparing the batch results with and without zeolite, it showed that the addition of 17 g/gSCOD zeolite gave larger COD decrease within 20 days of operation. In order to elucidate the mechanism, parameter estimations of 12 kinetic parameters were proposed to describe the batch reactor performance. The model in general could describe the batch experimental data well. In the second part of this study, the kinetic parameters obtained from batch reactor were used to simulate the performance of double column AFBR where the acidogenic and methanogenic biomass were separated. The simulation showed that a relatively long residence time (Hydraulic Residence Time, HRT) was required to treat POME using the proposed double column AFBR. Sensitivity analyses was conducted and revealed that μm1 appeared to be the most sensitive parameter to reduce the HRT of double column AFBR.
Influenza immunizations in the elderly: a continuous quality improvement project.
Juma, A; Evans, M F; Bloom, J
2000-08-01
As part of the continuous quality improvement program at The Toronto Hospital's Department of Family & Community Medicine (TTH-DFCM), it was considered necessary to examine the structures, processes and outcomes of influenza immunization for the elderly. The study sought to (a) document the current influenza immunization process; (b) quantify influenza immunization rates for elderly patients during two consecutive immunization seasons (1996 and 1997), and compare these rates across physician teams, attending staff vs. residents, patient gender, and patient age groups; (c) compare influenza immunization rates with other centers; and (d) identify barriers and propose solutions to improve influenza immunization rates in the elderly. Evaluation Formative Research. A computerized roster of 15,000 patients at The Toronto Hospital, Department of Family and Community Medicine, a University of Toronto academic teaching center. Active patients age 65 years and over. Influenza immunization. Physician Teams, Physician status, Patient gender, and Patient age group. Immunization rates of attendees increased from 75.4% to 78.7%; over 3% increase from 1996 to 1997. Major subgroups which benefited from increased immunization rates were patients in the Blue team, patients age 70-74 years, and female patients. This study presents a rigorous examination of the components of the influenza immunization program, and demonstrates improved immunization rates over a two-year period. Suggestions for future action have been identified. The study design can also serve as a model for future clinical quality improvement projects.
78 FR 58291 - TRICARE; Fiscal Year 2014 Continued Health Care Benefit Program Premium Update
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-23
... DEPARTMENT OF DEFENSE Office of the Secretary TRICARE; Fiscal Year 2014 Continued Health Care... Health Care Benefit Program Premiums for Fiscal Year 2014. SUMMARY: This notice provides the updated Continued Health Care Benefit Program Premiums for Fiscal Year 2014. DATES: The Fiscal Year 2014 rates...
Youth exposure to alcohol advertising on television--25 markets, United States, 2010.
2013-11-08
Excessive alcohol consumption accounted for an estimated 4,700 deaths and 280,000 years of potential life lost among youths aged <21 years each year during 2001-2005. Exposure to alcohol marketing increases the likelihood to varying degrees that youths will initiate drinking and drink at higher levels. By 2003, the alcohol industry voluntarily agreed not to advertise on television programs where >30% of the audience is reasonably expected to be aged <21 years. However, the National Research Council/Institute of Medicine (NRC/IOM) proposed in 2003 that "the industry standard should move toward a 15% threshold for television advertising". Because local media markets might have different age distributions, the Center on Alcohol Marketing and Youth, Johns Hopkins Bloomberg School of Public Health, evaluated the proportion of advertisements that appeared on television programs in 25 local television markets* and resulting youth exposure that exceeded the industry standard (i.e., >30% aged 2-20 years) or the proposed NRC/IOM standard (i.e., >15% aged 12-20 years). Among national television programs with alcohol advertising, placements were assessed for the 10 programs with the largest number of youth viewers within each of four program categories: network sports, network nonsports, cable sports, and cable nonsports (40 total). Of the 196,494 alcohol advertisements that aired on television programs with the largest number of youth viewers in these local markets, placement of 23.7% exceeded the industry threshold and 35.4% exceeded the NRC/IOM threshold. These results indicate that the alcohol industry's self-regulation of its advertising could be improved, and youth exposure to alcohol advertising could be further reduced by adopting and complying with the NRC/IOM standard. In addition, continued public health surveillance would allow for sustained assessment of youth exposure to alcohol advertising and inform future interventions.
Su, G; Madsen, P; Lund, M S
2009-05-01
Crossbreeding is currently increasing in dairy cattle production. Several studies have shown an environment-dependent heterosis [i.e., an interaction between heterosis and environment (H x E)]. An H x E interaction is usually estimated from a few discrete environment levels. The present study proposes a reaction norm model to describe H x E interaction, which can deal with a large number of environment levels using few parameters. In the proposed model, total heterosis consists of an environment-independent part, which is described as a function of heterozygosity, and an environment-dependent part, which is described as a function of heterozygosity and environmental value (e.g., herd-year effect). A Bayesian approach is developed to estimate the environmental covariates, the regression coefficients of the reaction norm, and other parameters of the model simultaneously in both linear and nonlinear reaction norms. In the nonlinear reaction norm model, the H x E is approximated using linear splines. The approach was tested using simulated data, which were generated using an animal model with a reaction norm for heterosis. The simulation study includes 4 scenarios (the combinations of moderate vs. low heritability and moderate vs. low herd-year variation) of H x E interaction in a nonlinear form. In all scenarios, the proposed model predicted total heterosis very well. The correlation between true heterosis and predicted heterosis was 0.98 in the scenarios with low herd-year variation and 0.99 in the scenarios with moderate herd-year variation. This suggests that the proposed model and method could be a good approach to analyze H x E interactions and predict breeding values in situations in which heterosis changes gradually and continuously over an environmental gradient. On the other hand, it was found that a model ignoring H x E interaction did not significantly harm the prediction of breeding value under the simulated scenarios in which the variance for environment-dependent heterosis effects was small (as it generally is), and sires were randomly used over production environments.
Gould, Elise
2007-01-01
In 2005, the percentage of Americans with employer-provided health insurance fell for the fifth year in a row. Workers and their families have been falling into the ranks of the uninsured at alarming rates. The downward trend in employer-provided coverage for children also continued into 2005. In the previous four years, children were less likely to become uninsured as public sector health coverage expanded, but in 2005 the rate of uninsured children increased. While Medicaid and SCHIP still work for many, the government has not picked up coverage for everybody who lost insurance. The weakening of this system-notably for children-is particularly difficult for workers and their families in a time of stagnating incomes. Furthermore, these programs are not designed to prevent low-income adults or middle- or high-income families from becoming uninsured. Government at the federal and state levels has responded to medical inflation with policy changes that reduce public insurance eligibility or with proposals to reduce government costs. Federal policy proposals to lessen the tax advantage of workplace insurance or to encourage a private purchase system could further destabilize the employer-provided system. Now is a critical time to consider health insurance reform. Several promising solutions could increase access to affordable health care. The key is to create large, varied, and stable risk pools.
A Summary History of Reusable Spaceplane Development in the Soviet Union
NASA Astrophysics Data System (ADS)
Siddiqi, A. A.
2002-01-01
Beginning the early years of space advocacy in the 1920s, the Soviets proposed a large number of winged space vehicle concepts as part of broader work on space transportation systems. These designs left an important legacy that has remained unexamined. In the 1920s, theorists and publicists such as Konstantin Tsiolkovskiy and Fridrikh Tsander were the earliest proponents of spaceplane designs. These were followed in the 1930s by the first concrete projects for rocket-propelled aircraft designed by the young Sergey Korolev. During World War II, the Soviets experimented with a number of rocket-planes, not for spaceflight, but for battle purposes. Subsequently, in the postwar years, the Soviet government for the first time funded a research project into a hypersonic winged vehicle for delivery of nuclear weapons. In later years, in the 1960s, with the growth of the Soviet space program, Soviet designers fielded a multitude of spaceplane programs that all culminated in the development of the famous Buran space shuttle. In this article, I will summarize all known hypersonic and spaceplane proposals during the Soviet era. Despite considerable funding, none of the spaceplane designs ever reached operational status. My goal is to highlight the technological lineage of Soviet and Russian reusable spaceplane concepts in the hope of illuminating design approaches that have continued to influence approaches to developing space transportation systems.
Smith, F; Singleton, A; Hilton, S
1998-01-01
BACKGROUND: The accreditation and provision of continuing education for general practitioners (GPs) is set to change with new proposals from the General Medical Council, the Government, and the Chief Medical Officer. AIM: To review the theories, policies, strategies, and effectiveness in GP continuing education in the past 10 years. METHOD: A systematic review of the literature by computerized and manual searches of relevant journals and books. RESULTS: Educational theory suggests that continuing education (CE) should be work-based and use the learner's experiences. Audit can play an important role in determining performance and needs assessment, but at present is largely a separate activity. Educational and professional support, such as through mentors or co-tutors, has been successfully piloted but awaits larger scale evaluation. Most accredited educational events are still the postgraduate centre lecture, and GP Tutors have a variable role in CE management and provision. Controlled trials of CE strategies suggest effectiveness is enhanced by personal feedback and work prompts. Qualitative studies have demonstrated that education plays only a small part in influencing doctors' behavior. CONCLUSION: Maintaining good clinical practice is on many stakeholders' agendas. A variety of methods may be effective in CE, and larger scale trials or evaluations are needed. PMID:10071406
Estimating conditional proportion curves by regression residuals.
Han, Bing; Lim, Nelson
2010-06-15
Researchers often derive a categorical outcome from an observed continuous measurement y. For example, human obesity status can be defined by the body mass index. They proceed to estimate the conditional proportion curve p(x) = P(y
5 CFR 890.1022 - Contesting proposed permissive debarments.
Code of Federal Regulations, 2010 CFR
2010-01-01
... SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Permissive Debarments § 890.1022 Contesting proposed permissive debarments...
Celiac disease: management of persistent symptoms in patients on a gluten-free diet.
Dewar, David H; Donnelly, Suzanne C; McLaughlin, Simon D; Johnson, Matthew W; Ellis, H Julia; Ciclitira, Paul J
2012-03-28
To investigate all patients referred to our center with non-responsive celiac disease (NRCD), to establish a cause for their continued symptoms. We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period. These individuals were investigated to establish the eitiology of their continued symptoms. The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement. They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion. A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible. Colonoscopy, lactulose hydrogen breath testing, pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted. Their clinical progress was followed over a minimum of 2 years. One hundred and twelve consecutive patients were referred with NRCD. Twelve were found not to have celiac disease (CD). Of the remaining 100 patients, 45% were not adequately adhering to a strict gluten-free diet, with 24 (53%) found to be inadvertently ingesting gluten, and 21 (47%) admitting non-compliance. Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%. Refractory CD was diagnosed in 9%. Three of these were diagnosed with intestinal lymphoma. After 2 years, 78 patients remained well, eight had continuing symptoms, and four had died. In individuals with NRCD, a remediable cause can be found in 90%: with continued gluten ingestion as the leading cause. We propose an algorithm for investigation.
76 FR 72505 - Agency Information Collection Activity; Proposed Collection
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-23
... DEPARTMENT OF THE TREASURY Internal Revenue Service Agency Information Collection Activity; Proposed Collection AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for... on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of...
7 CFR 3405.14 - Proposal review.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 15 2010-01-01 2010-01-01 false Proposal review. 3405.14 Section 3405.14 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Proposal Review and...
Bovine Pancreatic Ribonuclease: 50 Years of the First Enzymatic Reaction Mechanism†
Cuchillo, Claudi M.; Nogués, M. Victòria; Raines, Ronald T.
2011-01-01
Fifty years ago, the group of Tony Mathias and Bob Rabin at University College London, deduced the first mechanism for catalysis by an enzyme—ribonuclease (Findlay, D., Herries, D. G., Mathias, A. P., Rabin, B. R., and Ross, C.A. (1961). The active site and mechanism of action of bovine pancreatic ribonuclease, Nature 190, 781–784). Here, we celebrate this historic accomplishment by surveying knowledge of enzymology and protein science at that time, facts that led to the formulation of the mechanism, criticisms and alternative mechanisms, data that supported the proposed mechanism, and some of the refinements that have since provided a more precise picture of catalysis of RNA cleavage by ribonucleases. The Mathias and Rabin mechanism has appeared in numerous textbooks, monographs, and reviews, and continues to have a profound impact on biochemistry. PMID:21838247
A biometric analysis of brain size in micrencephalics.
Hofman, M A
1984-01-01
Brain weight and head circumference in micrencephalic patients were analysed as a function of age, height and sex in relation to normal human standards. A quantitative definition of micrencephaly is proposed, which is based on these analyses. Evidence is presented, furthermore, that micrencephalics have a significantly lower brain weight in adolescence than in early childhood, and that this cerebral dystrophy continues throughout adulthood, leading to death in more than 85% of the males and 78% of the females before they reach the age of 30 years. Since this decline in brain weight after approximately 3-5 years of age is not accompanied by a similar reduction in head circumference, the brains of elderly micrencephalic patients no longer occupy the entire cranial cavity. It is evident, therefore, that head circumference in the case of micrencephaly is an unsuitable parameter for estimating brain size.
40+ Years of Instrumentation for the La Silla Paranal Observatory
NASA Astrophysics Data System (ADS)
D'Odorico, S.
2018-03-01
As ESO Period 100 comes to a close, I look back at the development of ESO's instrumentation programme over more than 40 years. Instrumentation and detector activities were initially started by a small group of designers, engineers, technicians and astronomers while ESO was still at CERN in Geneva in the late 1970s. They have since led to the development of a successful suite of optical and infrared instruments for the La Silla Paranal Observatory, as testified by the continuous growth in the number of proposals for observing time and in the publications based on data from ESO telescopes. The instrumentation programme evolved significantly with the VLT and most instruments were developed by national institutes in close cooperation with ESO. This policy was a cornerstone of the VLT programme from the beginning and a key to its success.
EDUCATION IN BUSINESS AND INDUSTRY.
ERIC Educational Resources Information Center
DECARLO, CHARLES R.; ROBINSON, ORMSBEE W.
CONTINUING EDUCATION IS DISCUSSED AS VITAL TO THE PROSPERITY OF BUSINESS AND INDUSTRY WHEN TECHNOLOGICAL CHANGES REQUIRE CONTINUAL READJUSTMENT OF JOB REQUIREMENTS. ROLES OF INDUSTRY, UNIVERSITIES, AND GOVERNMENT COOPERATING TO PROVIDE THE RESOURCES, MATERIALS, AND INCENTIVES FOR CONTINUING EDUCATION ARE PROPOSED. DISCUSSIONS INCLUDE--(1) PROBLEMS…
Phillips, Steven P.; Carlson, Carl S.; Metzger, Loren F.; Howle, James F.; Galloway, Devin L.; Sneed, Michelle; Ikehara, Marti E.; Hudnut, Kenneth W.; King, Nancy E.
2003-01-01
Ground-water levels in Lancaster, California, declined more than 200 feet during the 20th century, resulting in reduced ground-water supplies and more than 6 feet of land subsidence. Facing continuing population growth, water managers are seeking solutions to these problems. Injection of imported, treated fresh water into the aquifer system when it is most available and least expensive, for later use during high-demand periods, is being evaluated as part of a management solution. The U.S. Geological Survey, in cooperation with the Los Angeles County Department of Public Works and the Antelope Valley-East Kern Water Agency, monitored a pilot injection program, analyzed the hydraulic and subsidence-related effects of injection, and developed a simulation/optimization model to help evaluate the effectiveness of using existing and proposed wells in an injection program for halting the decline of ground-water levels and avoiding future land subsidence while meeting increasing ground-water demand. A variety of methods were used to measure aquifer-system response to injection. Water levels were measured continuously in nested (multi-depth) piezometers and monitoring wells and periodically in other wells that were within several miles of the injection site. Microgravity surveys were done to estimate changes in the elevation of the water table in the absence of wells and to estimate specific yield. Aquifer-system deformation was measured directly and continuously using a dual borehole extensometer and indirectly using continuous Global Positioning System (GPS), first-order spirit leveling, and an array of tiltmeters. The injected water and extracted water were sampled periodically and analyzed for constituents, including chloride and trihalomethanes. Measured injection rates of about 750 gallons per minute (gal/min) per well at the injection site during a 5-month period showed that injection at or above the average extraction rates at that site (about 800 gal/min) was hydraulically feasible. Analyses of these data took many forms. Coupled measurements of gravity and water-level change were used to estimate the specific yield near the injection wells, which, in turn, was used to estimate areal water-table changes from distributed measurements of gravity change. Values of the skeletal components of aquifer-system storage, which are key subsidence-related characteristics of the system, were derived from continuous measurements of water levels and aquifer-system deformation. A numerical model of ground-water flow was developed for the area surrounding Lancaster and used to estimate horizontal and vertical hydraulic conductivities. A chemical mass balance was done to estimate the recovery of injected water. The ground-water-flow model was used to project changes in ground-water levels for 10 years into the future, assuming no injection, no change in pumping distribution, and forecasted increases in ground-water demand. Simulated ground-water levels decreased throughout the Lancaster area, suggesting that land subsidence would continue as would the depletion of ground-water supplies and an associated loss of well production capacity. A simulation/optimization model was developed to help identify optimal injection and extraction rates for 16 existing and 13 proposed wells to avoid future land subsidence and to minimize loss of well production capacity while meeting increasing ground-water demands. Results of model simulations suggest that these objectives can be met with phased installation of the proposed wells during the 10-year period. Water quality was not considered in the optimization, but chemical-mass-balance results indicate that a sustained injection program likely would have residual effects on the chemistry of ground water.
7 CFR 3406.21 - Intent to submit a proposal.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Submission of a Teaching or Research Proposal § 3406.21 Intent to submit a proposal. To assist CSREES in... 7 Agriculture 15 2010-01-01 2010-01-01 false Intent to submit a proposal. 3406.21 Section 3406.21 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION...
7 CFR 3406.22 - When and where to submit a proposal.
Code of Federal Regulations, 2010 CFR
2010-01-01
... PROGRAM Submission of a Teaching or Research Proposal § 3406.22 When and where to submit a proposal. The... 7 Agriculture 15 2010-01-01 2010-01-01 false When and where to submit a proposal. 3406.22 Section 3406.22 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH...
Krishnan, Shankar
2013-01-01
The worldwide need for rapid expansion and diversification of medical devices and the corresponding requirements in industry pose arduous challenges for educators to train undergraduate biomedical engineering (BME) students. Preparing BME students for working in the research and development (R&D) in medical device industry is not easily accomplished by adopting traditional pedagogical methods. Even with the inclusion of the design and development elements in capstone projects, medical device industry may be still experience a gap in fulfilling their needs in R&D. This paper proposes a new model based on interdisciplinary project-based learning (IDPBL) to address the requirements of building the necessary skill sets in academia for carrying out R&D in medical device industry. The proposed model incorporates IDPBL modules distributed in a stepwise fashion through the four years of a typical BME program. The proposed model involves buy-in and collaboration from faculty as well as students. The implementation of the proposed design in an undergraduate BME program is still in process. However, a variant of the proposed IDPBL method has been attempted at a limited scale at the postgraduate level and has shown some success. Extrapolating the previous results, the adoption of the IDPBL to BME training seems to suggest promising outcomes. Despite numerous implementation challenges, with continued efforts, the proposed IDPBL will be valuable n academia for skill sets building for medical device R&D.
5 CFR 890.1009 - Contesting proposed mandatory debarments.
Code of Federal Regulations, 2011 CFR
2011-01-01
... SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Mandatory Debarments § 890.1009 Contesting proposed mandatory debarments. (a...
Isolated laryngeal myasthenia gravis for 26 years.
Renard, Dimitri; Hedayat, Amir; Gagnard, Corinne
2015-02-01
Laryngeal myasthenia gravis is a relatively rare variant of myasthenia gravis. A vast portion of patients with initial laryngeal myasthenia gravis develop involvement of ocular and/or extra-ocular muscles during the years after symptom onset although a minority of laryngeal myasthenia gravis patients continues to have isolated laryngeal muscle involvement for several years. We present a 58-year-old woman with recurrent episodic isolated dysphonia (associated with diffuse bilateral vocal cord paresis on laryngoscopy) since the age of 32. Dysphonia became permanent since 6 months. A diagnosis of laryngeal myasthenia gravis was made based on abnormal single-fiber electromyography and spectacular response to pyridostigmine treatment. Repetitive nerve stimulation was normal and anti-acetylcholine receptor and anti-muscle specific tyrosine kinase antibodies were absent. This case shows that laryngeal myasthenia gravis can be isolated during 26 years of follow-up. We propose that even when myasthenia gravis seems unlikely as underlying mechanism of isolated dysphonia (because of lack of antibodies, normal repetitive nerve stimulation, and absence of extra-laryngeal involvement after years of follow-up), single-fiber electromyography should be performed and myasthenia gravis treatment should be tried. Copyright © 2014 Elsevier B.V. All rights reserved.
Code of Federal Regulations, 2010 CFR
2010-01-01
... of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... Procedure Governing Proceedings To Formulate Marketing Agreements and Marketing Orders § 900.3 Proposals. (a) A marketing agreement or a marketing order may be proposed by the Secretary or by any other person...
78 FR 64293 - Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-28
... DEPARTMENT OF THE TREASURY Internal Revenue Service [Form 1120-RIC] Proposed Collection; Comment... proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995... to the form at this time. Type of Review: Extension of a currently approved collection. Affected...
77 FR 13154 - Proposed Collection; Comments Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-05
... NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES Proposed Collection; Comments Request AGENCY: National Endowment for the Arts, National Foundation on the Arts and Humanities. ACTION: Proposed collection; comments request. SUMMARY: The National Endowment for the Arts (NEA), as part of its continuing...
Continuous spin fields of mixed-symmetry type
NASA Astrophysics Data System (ADS)
Alkalaev, Konstantin; Grigoriev, Maxim
2018-03-01
We propose a description of continuous spin massless fields of mixed-symmetry type in Minkowski space at the level of equations of motion. It is based on the appropriately modified version of the constrained system originally used to describe massless bosonic fields of mixed-symmetry type. The description is shown to produce generalized versions of triplet, metric-like, and light-cone formulations. In particular, for scalar continuous spin fields we reproduce the Bekaert-Mourad formulation and the Schuster-Toro formulation. Because a continuous spin system inevitably involves infinite number of fields, specification of the allowed class of field configurations becomes a part of its definition. We show that the naive choice leads to an empty system and propose a suitable class resulting in the correct degrees of freedom. We also demonstrate that the gauge symmetries present in the formulation are all Stueckelberg-like so that the continuous spin system is not a genuine gauge theory.
Segmenting Continuous Motions with Hidden Semi-markov Models and Gaussian Processes
Nakamura, Tomoaki; Nagai, Takayuki; Mochihashi, Daichi; Kobayashi, Ichiro; Asoh, Hideki; Kaneko, Masahide
2017-01-01
Humans divide perceived continuous information into segments to facilitate recognition. For example, humans can segment speech waves into recognizable morphemes. Analogously, continuous motions are segmented into recognizable unit actions. People can divide continuous information into segments without using explicit segment points. This capacity for unsupervised segmentation is also useful for robots, because it enables them to flexibly learn languages, gestures, and actions. In this paper, we propose a Gaussian process-hidden semi-Markov model (GP-HSMM) that can divide continuous time series data into segments in an unsupervised manner. Our proposed method consists of a generative model based on the hidden semi-Markov model (HSMM), the emission distributions of which are Gaussian processes (GPs). Continuous time series data is generated by connecting segments generated by the GP. Segmentation can be achieved by using forward filtering-backward sampling to estimate the model's parameters, including the lengths and classes of the segments. In an experiment using the CMU motion capture dataset, we tested GP-HSMM with motion capture data containing simple exercise motions; the results of this experiment showed that the proposed GP-HSMM was comparable with other methods. We also conducted an experiment using karate motion capture data, which is more complex than exercise motion capture data; in this experiment, the segmentation accuracy of GP-HSMM was 0.92, which outperformed other methods. PMID:29311889
Liu, Kai-Chun; Chan, Chia-Tai
2017-01-01
The proportion of the aging population is rapidly increasing around the world, which will cause stress on society and healthcare systems. In recent years, advances in technology have created new opportunities for automatic activities of daily living (ADL) monitoring to improve the quality of life and provide adequate medical service for the elderly. Such automatic ADL monitoring requires reliable ADL information on a fine-grained level, especially for the status of interaction between body gestures and the environment in the real-world. In this work, we propose a significant change spotting mechanism for periodic human motion segmentation during cleaning task performance. A novel approach is proposed based on the search for a significant change of gestures, which can manage critical technical issues in activity recognition, such as continuous data segmentation, individual variance, and category ambiguity. Three typical machine learning classification algorithms are utilized for the identification of the significant change candidate, including a Support Vector Machine (SVM), k-Nearest Neighbors (kNN), and Naive Bayesian (NB) algorithm. Overall, the proposed approach achieves 96.41% in the F1-score by using the SVM classifier. The results show that the proposed approach can fulfill the requirement of fine-grained human motion segmentation for automatic ADL monitoring. PMID:28106853
A proposed campaign to increase the use of restraint systems for young children who ride in cars.
Shaw, C E; Fluke, D M
1983-01-01
In the United States, motor vehicle accidents are the number one killer of children under 5 years of age, according to the National Highway Traffic Safety Administration (NHTSA). Repeated studies show that correct, consistent use of child restraint systems is a proven method of preventing many unnecessary deaths. Yet current data from NHTSA's National Accident Sampling Survey show that only 35 percent of infants under 1 year of age, and only 25 percent of toddlers between 1 and 4, are protected by child restraints when they ride in cars. The authors believe that an innovative public awareness campaign, based on a Presidential proclamation giving national priority to encouraging correct use of child restraint systems, would serve both to increase the public's knowledge of car safety issues and to increase the number of parents who provide restraint protection for their children. Our proposal is unique in that it is a multidimensional approach with its main focus on children under 5 as a target population. We advocate continued appeal to the adult consumer population but believe that long-term results will be more significant if children are addressed as well. The main emphasis of our proposal is on local community involvement, yet Federal acknowledgement of the problem of safety for small children in cars--and support of efforts to solve this problem--are necessary to reinforce the efforts of grassroots organizations. PMID:6414038
Obeidat, Akef S; Alhaqwi, Ali Ibrahim; Abdulghani, Hamza Mohammad
2015-04-01
There are numerous national efforts to determine and develop research priorities of medical education in Saudi Arabia. These priorities were first proposed in 2010 by "Dr Al-Khuli's Chair for Developing Medical Education in Saudi Arabia". The proposed priority domains were: curriculum, students, faculty, and quality assurance and accreditation. To investigate publications in medical education at the national and international levels in areas relating to these proposed priorities. Electronic search within PubMed database for papers relating to each domain of priority was conducted at national and international levels in the last three years, using the same keywords as the priority domains, but only confined to undergraduate medical education. Out of 3145 articles retrieved when searching with keyword as broad as "undergraduate medical curriculum" only 81 articles worldwide and 3 articles from Saudi Arabia were dealing with curriculum related issues as a whole. Further search on the sub-domains "effective strategies to manage undergraduate curriculum" and "undergraduate medical education models", resulted in the retrieval of few articles worldwide and none from Saudi Arabia. At the national level, there were 63 publications from Saudi Arabia that were either course (topic)-specific or could not be classified under the four domains specified by Dr Al-Khuli's Chair. Research activities in medical education in Saudi Arabia in the last 3 years showed diversity and lack of focus in the research priorities. Efforts of academic and research centers should continue to monitor and encourage these activities toward achieving the recommended priorities.
22 CFR 513.220 - Continuation of covered transactions.
Code of Federal Regulations, 2010 CFR
2010-04-01
... and participants shall not renew or extend covered transactions (other than no-cost time extensions... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Continuation of covered transactions. 513.220... Continuation of covered transactions. (a) Notwithstanding the debarment, suspension, proposed debarment under...
Sustaining Nursing and Midwifery Grand Rounds in a Regional Australian Health Service.
Smyth, Wendy; Abernethy, Gail
2016-07-01
This article reports the success, or otherwise, of strategies implemented to sustain nursing grand rounds in a large regional health service in North Queensland, Australia. Nursing grand rounds had been introduced in late 2010 to increase nurses' engagement with research and evidence-based practice. Although the format, topics, and purpose of grand rounds have changed, attendees continue to positively evaluate each presentation. However, after 5 years, the initiative has expanded and somewhat modified its focus. This article describes these changes and proposes options for the future progression of this professional development activity. J Contin Educ Nurs. 2016;47(7):316-320. Copyright 2016, SLACK Incorporated.
Dystrophic calcification of the prostate after cryotherapy.
Dru, Christopher; Bender, Leon
2014-01-01
We present a previously undocumented complication of dystrophic calcification of the prostate after cryotherapy. An 87-year-old male presented with recurrent lower urinary tract infections and was found to have an obstructing large calcified mass in the right lobe of the prostate. Subsequently, he underwent transurethral resection of the prostate (TURP) and bladder neck with laser lithotripsy to remove the calculus. We propose that chronic inflammation and necrosis of the prostate from cryotherapy resulted in dystrophic calcification of the prostate. As the use of cryotherapy for the treatment of localized prostate cancer continues to increase, it is important that clinicians be aware of this scenario and the technical challenges it poses.
The principles of teratology: are they still true?
Friedman, Jan M
2010-10-01
James Wilson originally proposed a set of "Principles of Teratology" in 1959, the year before he helped to found the Teratology Society. By 1977, when these Principles were presented in a more definitive form in Wilson and Fraser's Handbook of Teratology, they had become a standard formulation of the basic tenets of the field. Wilson's Principles have continued to guide scientific research in teratology, and they are widely used in teaching. Recent advances in our knowledge of the molecular and cellular bases of embryogenesis serve only to provide a deeper understanding of the fundamental developmental mechanisms that underlie Wilson's Principles of Teratology. © 2010 Wiley-Liss, Inc.
Preliminary studies of elevated atmospheric CO/sub 2/ on conifers, May 1-December 30, 1985
DOE Office of Scientific and Technical Information (OSTI.GOV)
Helms, J.A.
1985-01-01
The original scope of work consisted of two parts: Intensive physiological studies of Pinus ponderosa seedlings and saplings that were continuously exposed to various levels of CO/sub 2/ and SO/sub 2/ in open-topped chambers. Site selection and preparation in anticipation of DOE approval of a proposed 5-year project on effects of long-term exposure of forest vegetation to enhanced CO/sub 2/. Establishment of 5 Nelder-type plots utilizing 5 western conifers to permit fundamental studies on the physiological bases of tree-to-tree competition. Because the DOE project was not funded, site selection was abandoned.
Continuous EEG signal analysis for asynchronous BCI application.
Hsu, Wei-Yen
2011-08-01
In this study, we propose a two-stage recognition system for continuous analysis of electroencephalogram (EEG) signals. An independent component analysis (ICA) and correlation coefficient are used to automatically eliminate the electrooculography (EOG) artifacts. Based on the continuous wavelet transform (CWT) and Student's two-sample t-statistics, active segment selection then detects the location of active segment in the time-frequency domain. Next, multiresolution fractal feature vectors (MFFVs) are extracted with the proposed modified fractal dimension from wavelet data. Finally, the support vector machine (SVM) is adopted for the robust classification of MFFVs. The EEG signals are continuously analyzed in 1-s segments, and every 0.5 second moves forward to simulate asynchronous BCI works in the two-stage recognition architecture. The segment is first recognized as lifted or not in the first stage, and then is classified as left or right finger lifting at stage two if the segment is recognized as lifting in the first stage. Several statistical analyses are used to evaluate the performance of the proposed system. The results indicate that it is a promising system in the applications of asynchronous BCI work.
Proposal for an Evaluation Method for the Performance of Work Procedures.
Mohammed, Mouda; Mébarek, Djebabra; Wafa, Boulagouas; Makhlouf, Chati
2016-12-01
Noncompliance of operators with work procedures is a recurrent problem. This human behavior has been said to be situational and studied by many different approaches (ergonomic and others), which consider the noncompliance with work procedures to be obvious and seek to analyze its causes as well as consequences. The object of the proposed method is to solve this problem by focusing on the performance of work procedures and ensuring improved performance on a continuous basis. This study has multiple results: (1) assessment of the work procedures' performance by a multicriteria approach; (2) the use of a continuous improvement approach as a framework for the sustainability of the assessment method of work procedures' performance; and (3) adaptation of the Stop-Card as a facilitator support for continuous improvement of work procedures. The proposed method emphasizes to put in value the inputs of continuous improvement of the work procedures in relation with the conventional approaches which adopt the obvious evidence of the noncompliance to the working procedures and seek to analyze the cause-effect relationships related to this unacceptable phenomenon, especially in strategic industry.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Allen, Melissa R
2013-10-01
The following pages represent the status of policy regarding adaptation of the electric grid to climate change and proposed directions for new policy development. While strides are being made to understand the current climate and to predict hazards it may present to human systems, both the science and the policy remain at present in an analytical state. The policy proposed in this document involves first continued computational modeling of outcomes which will produce a portfolio of options to be considered in light of specific region-related risks. It is proposed that the modeling continue not only until reasonable policy at variousmore » levels of jurisdiction can be derived from its outcome but also on a continuing basis so that as improvements in the understanding of the state and trajectory of climate science along with advancements in technology arise, they can be incorporated into an appropriate and evolving policy.« less
Kwonjoon Lee; Kiseok Song; Taehwan Roh; Hoi-Jun Yoo
2016-08-01
The wrist patch-type ECG/APW sensor system is proposed for continuous and comprehensive monitoring of the patient's cardiovascular system. The wrist patch-type ECG/APW sensor system is consists of ECG/APW sensor, ECG/APW electrodes, and base station for real-time monitoring of the patient's status. The ECG/APW sensor and electrodes are composed of wrist patch, bandage-type ECG electrode and fabric APW electrode, respectively so that the patient's cardiovascular system can be continuously monitored in daily life with free hand-movement. Since the proposed wrist patchtype ECG/APW sensor simultaneously measures ECG/APW, the cardiac indicators, such as HR and PAT, can be extracted for comprehensive and accurate monitoring of the patient's cardiovascular system. The proposed wrist patch-type ECG/APW sensor system is successfully verified using the commercial PPG sensor (RP520) and demonstrated with the customized Android application on the smart phone.
An analysis of the early-warning system in emerging markets for reducing the financial crisis
NASA Astrophysics Data System (ADS)
Shen, Xiangguang; Song, Xiaozhong
2009-07-01
The large number of financial crises in emerging markets over the past ten years has left many observers, both from academia and financial institutions, puzzled by an apparent lack of homogenous causal relations between endogenous economic variables and the bursting of large financial shocks. The frequency of financial crises in the last 20 years can be attributed to the lack of a comprehensive theory of financial regulation to guide policy makers. Existing theories fail to define the range of regulatory models, the causes of regulatory failure, and how to measure and prevent it. Faulty design of regulatory models, and the lack of ongoing performance monitoring incorporating early warning systems, is disrupting economic and social development. The main aim of this article is to propose an early warning system (EWS) which purposes issuing warning signal against the possible financial crisis in the emerging market, and makes the emerging market survived the first wave of the crisis be able to continue their operation in the following years.
On the possibility of producing definitive magnetic observatory data within less than one year
NASA Astrophysics Data System (ADS)
Mandić, Igor; Korte, Monika
2017-04-01
Geomagnetic observatory data are fundamental in geomagnetic field studies and are widely used in other applications. Often they are combined with satellite and ground survey data. Unfortunately, the observatory definitive data are only available with a time lag ranging from several months up to more than a year. The reason for this lag is the annual production of the final calibration values, i.e. baselines that are used to correct preliminary data from continuously recording magnetometers. In this paper, we will show that the preparation of definitive geomagnetic data is possible within a calendar year and presents an original method for prompt and automatic estimation of the observatory baselines. The new baselines, obtained in a mostly automatic manner, are compared with the baselines reported on INTERMAGNET DVDs for the 2009-2011 period. The high quality of the baselines obtained by the proposed method indicates its suitability for data processing in fully automatic observatories when automated absolute instruments will be deployed at remote sites.
Evolution of Mass Movements near Epicentre of Wenchuan Earthquake, the First Eight Years
Zhang, Shuai; Zhang, Limin; Lacasse, Suzanne; Nadim, Farrokh
2016-01-01
It is increasingly clear that landslides represent a major cause of economic costs and deaths in earthquakes in mountains. In the Wenchuan earthquake case, post-seismic cascading landslides continue to represent a major problem eight years on. Failure to anticipate the impact of cascading landslides could lead to unexpected losses of human lives and properties. Previous studies tended to focus on separate landslide processes, with little attention paid to the quantification of long-term evolution of multiple processes or the evolution of mass movements. The very active mass movements near the epicentre of the Wenchuan earthquake provided us a unique opportunity to understand the complex processes of the evolving cascading landslides after a strong earthquake. This study budgets the mass movements on the hillslopes and in the channels in the first eight years since the Wenchuan earthquake and verify a conservation in mass movements. A system illustrating the evolution and interactions of mass movement after a strong earthquake is proposed. PMID:27824077
Elenchezhiyan, M; Prakash, J
2015-09-01
In this work, state estimation schemes for non-linear hybrid dynamic systems subjected to stochastic state disturbances and random errors in measurements using interacting multiple-model (IMM) algorithms are formulated. In order to compute both discrete modes and continuous state estimates of a hybrid dynamic system either an IMM extended Kalman filter (IMM-EKF) or an IMM based derivative-free Kalman filters is proposed in this study. The efficacy of the proposed IMM based state estimation schemes is demonstrated by conducting Monte-Carlo simulation studies on the two-tank hybrid system and switched non-isothermal continuous stirred tank reactor system. Extensive simulation studies reveal that the proposed IMM based state estimation schemes are able to generate fairly accurate continuous state estimates and discrete modes. In the presence and absence of sensor bias, the simulation studies reveal that the proposed IMM unscented Kalman filter (IMM-UKF) based simultaneous state and parameter estimation scheme outperforms multiple-model UKF (MM-UKF) based simultaneous state and parameter estimation scheme. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.
Efficient 3D multi-region prostate MRI segmentation using dual optimization.
Qiu, Wu; Yuan, Jing; Ukwatta, Eranga; Sun, Yue; Rajchl, Martin; Fenster, Aaron
2013-01-01
Efficient and accurate extraction of the prostate, in particular its clinically meaningful sub-regions from 3D MR images, is of great interest in image-guided prostate interventions and diagnosis of prostate cancer. In this work, we propose a novel multi-region segmentation approach to simultaneously locating the boundaries of the prostate and its two major sub-regions: the central gland and the peripheral zone. The proposed method utilizes the prior knowledge of the spatial region consistency and employs a customized prostate appearance model to simultaneously segment multiple clinically meaningful regions. We solve the resulted challenging combinatorial optimization problem by means of convex relaxation, for which we introduce a novel spatially continuous flow-maximization model and demonstrate its duality to the investigated convex relaxed optimization problem with the region consistency constraint. Moreover, the proposed continuous max-flow model naturally leads to a new and efficient continuous max-flow based algorithm, which enjoys great advantages in numerics and can be readily implemented on GPUs. Experiments using 15 T2-weighted 3D prostate MR images, by inter- and intra-operator variability, demonstrate the promising performance of the proposed approach.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-07
... DEPARTMENT OF LABOR Employee Benefits Security Administration Proposed Extension of Information Collection Requests Submitted for Public Comment: Disclosures by Insurers to General Account Policyholders... with an opportunity to comment on proposed and continuing collections of information. This helps the...
7 CFR 3403.9 - Submission of proposals.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 15 2011-01-01 2011-01-01 false Submission of proposals. 3403.9 Section 3403.9 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Submission and Evaluation of Proposals § 3403.9...
7 CFR 3403.9 - Submission of proposals.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 15 2013-01-01 2013-01-01 false Submission of proposals. 3403.9 Section 3403.9 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Submission and Evaluation of Proposals § 3403.9...
7 CFR 3403.9 - Submission of proposals.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 15 2014-01-01 2014-01-01 false Submission of proposals. 3403.9 Section 3403.9 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Submission and Evaluation of Proposals § 3403.9...
7 CFR 3403.9 - Submission of proposals.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 15 2012-01-01 2012-01-01 false Submission of proposals. 3403.9 Section 3403.9 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Submission and Evaluation of Proposals § 3403.9...
40 CFR 231.3 - Procedures for proposed determinations.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Procedures for proposed determinations. 231.3 Section 231.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.3 Procedures for proposed determinations. (a) If the Regional...
40 CFR 231.3 - Procedures for proposed determinations.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Procedures for proposed determinations. 231.3 Section 231.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.3 Procedures for proposed determinations. (a) If the Regional...
49 CFR 553.13 - Notice of proposed rulemaking.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 6 2010-10-01 2010-10-01 false Notice of proposed rulemaking. 553.13 Section 553.13 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC... Rules § 553.13 Notice of proposed rulemaking. Unless the Administrator, for good cause, finds that...
40 CFR 750.2 - Notice of proposed rulemaking.
Code of Federal Regulations, 2014 CFR
2014-07-01
..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...
40 CFR 750.2 - Notice of proposed rulemaking.
Code of Federal Regulations, 2013 CFR
2013-07-01
..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...
40 CFR 750.2 - Notice of proposed rulemaking.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...
40 CFR 750.2 - Notice of proposed rulemaking.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...
40 CFR 750.2 - Notice of proposed rulemaking.
Code of Federal Regulations, 2012 CFR
2012-07-01
..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...
ASTER system operating achievement for 15 years on orbit
NASA Astrophysics Data System (ADS)
Inada, Hitomi; Ito, Yoshiyuki; Kikuchi, Masakuni; Sakuma, Fumihiro; Tatsumi, Kenji; Akagi, Shigeki; Ono, Hidehiko
2015-10-01
ASTER (Advanced Spaceborne Thermal Emission and Reflection Radiometer) System is operating more than 15 years since launched on board of NASA's Terra spacecraft in December 1999. ASTER System is composed of 3 radiometers (VNIR (Visible and Near Infrared Radiometer), SWIR (Short-Wave Infrared Radiometer), and TIR (Thermal Infrared Radiometer)), CSP (Common Signal Processor) and MSP (Master Power Supply). This paper describes the ASTER System operating history and the achievement of ASTER System long term operation since the initial checkout operation, the normal operation, and the continuous operation. Through the 15 years operation, ASTER system had totally checked the all subsystems (MPS, VNIR, TIR, SWIR, and CSP) health and safety check using telemetry data trend evaluation, and executed the necessary action. The watch items are monitored as the life control items. The pointing mechanics for VNIR, SWIR and TIR, and the cooler for SWIR and TIR are all operating with any problem for over 15 years. In 2003, ASTER was successfully operated for the lunar calibration. As the future plan, ASTER team is proposing the 2nd lunar calibration before the end of mission.
The limits of two-year bioassay exposure regimens for identifying chemical carcinogens.
Huff, James; Jacobson, Michael F; Davis, Devra Lee
2008-11-01
Chemical carcinogenesis bioassays in animals have long been recognized and accepted as valid predictors of potential cancer hazards to humans. Most rodent bioassays begin several weeks after birth and expose animals to chemicals or other substances, including workplace and environmental pollutants, for 2 years. New findings indicate the need to extend the timing and duration of exposures used in the rodent bioassay. In this Commentary, we propose that the sensitivity of chemical carcinogenesis bio-assays would be enhanced by exposing rodents beginning in utero and continuing for 30 months (130 weeks) or until their natural deaths at up to about 3 years. Studies of three chemicals of different structures and uses-aspartame, cadmium, and toluene-suggest that exposing experimental animals in utero and continuing exposure for 30 months or until their natural deaths increase the sensitivity of bioassays, avoid false-negative results, and strengthen the value and validity of results for regulatory agencies. Government agencies, drug companies, and the chemical industry should conduct and compare the results of 2-year bioassays of known carcinogens or chemicals for which there is equivocal evidence of carcinogenicity with longer-term studies, with and without in utero exposure. If studies longer than 2 years and/or with in utero exposure are found to better identify potential human carcinogens, then regulatory agencies should promptly revise their testing guidelines, which were established in the 1960s and early 1970s. Changing the timing and dosing of the animal bioassay would enhance protection of workers and consumers who are exposed to potentially dangerous workplace or home contaminants, pollutants, drugs, food additives, and other chemicals throughout their lives.
The Limits of Two-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens
Huff, James; Jacobson, Michael F.; Davis, Devra Lee
2008-01-01
Background Chemical carcinogenesis bioassays in animals have long been recognized and accepted as valid predictors of potential cancer hazards to humans. Most rodent bioassays begin several weeks after birth and expose animals to chemicals or other substances, including workplace and environmental pollutants, for 2 years. New findings indicate the need to extend the timing and duration of exposures used in the rodent bioassay. Objectives In this Commentary, we propose that the sensitivity of chemical carcinogenesis bio-assays would be enhanced by exposing rodents beginning in utero and continuing for 30 months (130 weeks) or until their natural deaths at up to about 3 years. Discussion Studies of three chemicals of different structures and uses—aspartame, cadmium, and toluene—suggest that exposing experimental animals in utero and continuing exposure for 30 months or until their natural deaths increase the sensitivity of bioassays, avoid false-negative results, and strengthen the value and validity of results for regulatory agencies. Conclusions Government agencies, drug companies, and the chemical industry should conduct and compare the results of 2-year bioassays of known carcinogens or chemicals for which there is equivocal evidence of carcinogenicity with longer-term studies, with and without in utero exposure. If studies longer than 2 years and/or with in utero exposure are found to better identify potential human carcinogens, then regulatory agencies should promptly revise their testing guidelines, which were established in the 1960s and early 1970s. Changing the timing and dosing of the animal bioassay would enhance protection of workers and consumers who are exposed to potentially dangerous workplace or home contaminants, pollutants, drugs, food additives, and other chemicals throughout their lives. PMID:19057693
Albiach-Serrano, Anna; Sebastián-Enesco, Carla; Seed, Amanda; Colmenares, Fernando; Call, Josep
2015-11-01
When presented with the broken cloth problem, both human children and nonhuman great apes prefer to pull a continuous cloth over a discontinuous cloth in order to obtain a desired object resting on top. This has been interpreted as evidence that they preferentially attend to the functionally relevant cues of the task (e.g., presence or absence of a gap along the cloth). However, there is controversy regarding whether great apes' behavior is underpinned by causal knowledge, involving abstract concepts (e.g., support, connection), or by perceptual knowledge, based on percepts (e.g., contact, continuity). We presented chimpanzees, orangutans, and 2-, 3-, and 4-year-old children with two versions of the broken cloth problem. The Real condition, made with paper strips, could be solved based on either perceptual cues or causal knowledge. The Painted condition, which looked very similar, could be solved only by attending to perceptual cues. All groups mastered the Real condition, in line with previous results. Older children (3- and 4-year-olds) performed significantly better in this condition than all other groups, but the performance of apes and children did not differ sharply, with 2-year-olds and apes obtaining similar results. In contrast, only 4-year-olds solved the Painted condition. We propose causal knowledge to explain the general good performance of apes and humans in the Real condition compared with the Painted condition. In addition, we suggest that symbolic knowledge might account for 4-year-olds' performance in the Painted condition. Our findings add to the growing literature supporting the idea that learning from arbitrary cues is not a good explanation for the performance of apes and humans on some kinds of physical task. Copyright © 2015 Elsevier Inc. All rights reserved.
Robust Adaptive Dynamic Programming of Two-Player Zero-Sum Games for Continuous-Time Linear Systems.
Fu, Yue; Fu, Jun; Chai, Tianyou
2015-12-01
In this brief, an online robust adaptive dynamic programming algorithm is proposed for two-player zero-sum games of continuous-time unknown linear systems with matched uncertainties, which are functions of system outputs and states of a completely unknown exosystem. The online algorithm is developed using the policy iteration (PI) scheme with only one iteration loop. A new analytical method is proposed for convergence proof of the PI scheme. The sufficient conditions are given to guarantee globally asymptotic stability and suboptimal property of the closed-loop system. Simulation studies are conducted to illustrate the effectiveness of the proposed method.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-06
...The Department of the Treasury, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to comment on proposed and continuing information collections, as required by the Paperwork Reduction Act of 1995, 44 U.S.C. 3507. The Office of Thrift Supervision within the Department of the Treasury will submit the proposed information collection requirement described below to the Office of Management and Budget (OMB) for review, as required by the Paperwork Reduction Act. Today, OTS is soliciting public comments on its proposal to extend this information collection.
Fifty years of longitudinal continuity in general practice: a retrospective observational study.
White, Eleanor S; Pereira Gray, Denis; Langley, Peter; Evans, Philip H
2016-04-01
Continuity of care has been defined as relational continuity between patient and doctor and longitudinal continuity describing the duration of the relationship. Measurement of longitudinal continuity alone is associated with outcomes including patient satisfaction, medical costs, hospital admissions and mortality. In one UK general practice, records were searched for patients with continuous registration for 50 or more years. Characteristics of these patients were analysed for age, gender, social deprivation, partner registration and length of registration. Trends in numbers and proportions of this group over the previous 14 years were determined. A comparison group of patients, aged 50 or more, and registered in the same practice within the last 2-4 years, was identified. Patients registered for 50 years or more with a median registration of 56.2 years numbered 190 out of a population of 8420 (2.3%). These patients increased in number by 35.3% (1.7-2.3%) over 14 consecutive years. There were no differences between groups for GP consultation rate, number of repeat medications and hospital use, despite the significantly higher prevalence of multi-morbidity, depression and diabetes in patients with high continuity. This is the first report of 50-year continuity in general practice. Numbers of such patients and proportions are increasing. Longitudinal continuity is easily measured in general practice and associated with important clinical outcomes. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
An Update on the NASA Planetary Science Division Research and Analysis Program
NASA Astrophysics Data System (ADS)
Bernstein, Max; Richey, Christina; Rall, Jonathan
2015-11-01
Introduction: NASA’s Planetary Science Division (PSD) solicits its research and analysis (R&A) programs each year in Research Opportunities in Space and Earth Sciences (ROSES). Beginning with the 2014 ROSES solicitation, PSD changed the structure of the program elements under which the majority of planetary science R&A is done. Major changes included the creation of five core research program elements aligned with PSD’s strategic science questions, the introduction of several new R&A opportunities, new submission requirements, and a new timeline for proposal submission.ROSES and NSPIRES: ROSES contains the research announcements for all of SMD. Submission of ROSES proposals is done electronically via NSPIRES: http://nspires.nasaprs.com. We will present further details on the proposal submission process to help guide younger scientists. Statistical trends, including the average award size within the PSD programs, selections rates, and lessons learned, will be presented. Information on new programs will also be presented, if available.Review Process and Volunteering: The SARA website (http://sara.nasa.gov) contains information on all ROSES solicitations. There is an email address (SARA@nasa.gov) for inquiries and an area for volunteer reviewers to sign up. The peer review process is based on Scientific/Technical Merit, Relevance, and Level of Effort, and will be detailed within this presentation.ROSES 2015 submission changes: All PSD programs will continue to use a two-step proposal submission process. A Step-1 proposal is required and must be submitted electronically by the Step-1 due date. The Step-1 proposal should include a description of the science goals and objectives to be addressed by the proposal, a brief description of the methodology to be used to address the science goals and objectives, and the relevance of the proposed research to the call submitted to.
Wu, Mixia; Zhang, Dianchen; Liu, Aiyi
2016-01-01
New biomarkers continue to be developed for the purpose of diagnosis, and their diagnostic performances are typically compared with an existing reference biomarker used for the same purpose. Considerable amounts of research have focused on receiver operating characteristic curves analysis when the reference biomarker is dichotomous. In the situation where the reference biomarker is measured on a continuous scale and dichotomization is not practically appealing, an index was proposed in the literature to measure the accuracy of a continuous biomarker, which is essentially a linear function of the popular Kendall's tau. We consider the issue of estimating such an accuracy index when the continuous reference biomarker is measured with errors. We first investigate the impact of measurement errors on the accuracy index, and then propose methods to correct for the bias due to measurement errors. Simulation results show the effectiveness of the proposed estimator in reducing biases. The methods are exemplified with hemoglobin A1c measurements obtained from both the central lab and a local lab to evaluate the accuracy of the mean data obtained from the metered blood glucose monitoring against the centrally measured hemoglobin A1c from a behavioral intervention study for families of youth with type 1 diabetes.
Epilepsy Care in Ontario: An Economic Analysis of Increasing Access to Epilepsy Surgery
Bowen, James M.; Snead, O. Carter; Chandra, Kiran; Blackhouse, Gord; Goeree, Ron
2012-01-01
Background In August 2011 a proposed epilepsy care model was presented to the Ontario Health Technology Advisory Committee (OHTAC) by an Expert Panel on a Provincial Strategy for Epilepsy Care in Ontario. The Expert Panel recommended leveraging existing infrastructure in the province to provide enhanced capacity for epilepsy care. The point of entry for epilepsy care and the diagnostic evaluation for surgery candidacy and the epilepsy surgery would occur at regional and district epilepsy centres in London, Hamilton, Toronto, and Ottawa and at new centres recommended for northern and eastern Ontario. This economic analysis report was requested by OHTAC to provide information about the estimated budgetary impact on the Ontario health care system of increasing access to epilepsy surgery and to examine the cost-effectiveness of epilepsy surgery in both children and adults. Methods A prevalence-based “top-down” health care system budgetary impact model from the perspective of the Ministry of Health and Long-Term Care was developed to estimate the potential costs associated with expanding health care services to increase access to epilepsy care in general and epilepsy surgery in particular. A 5-year period (i.e., 2012–2016) was used to project annual costs associated with incremental epilepsy care services. Ontario Health Survey estimates of epilepsy prevalence, published epilepsy incidence data, and Canadian Census results for Ontario were used to approximate the number of individuals with epilepsy in the province. Applying these population estimates to data obtained from a recent field evaluation study that examined patterns of care and costs associated with epilepsy surgery in children, a health care system budget impact was calculated and the total costs and incremental costs associated with increasing access to surgery was estimated. In order to examine the cost-effectiveness of epilepsy surgery in children, a decision analysis compared epilepsy surgery to continued medical management in children with medically intractable epilepsy. Data from the field evaluation were combined with various published data to estimate the costs and outcomes for children with drug-refractory epilepsy over a 20-year period. Outcomes were defined as the number of quality-adjusted life years (QALYs) accumulated over 20 years following epilepsy surgery. Results There are about 20,981 individuals with medically intractable epilepsy in Ontario. Of these, 9,619 (1,441 children and 8,178 adults) could potentially be further assessed at regional epilepsy centres for suitability for epilepsy surgery, following initial evaluation at a district epilepsy care centre. The health care system impact analysis related to increasing access to epilepsy surgery in the Ontario through the addition of epilepsy monitoring unit (EMU) beds with video electroencephalography (vEEG) monitoring (total capacity of 15 pediatric EMU beds and 35 adult EMU beds distributed across the province) and the associated clinical resources is estimated to require an incremental $18.1 million (Cdn) annually over the next 5 years from 2012 to 2016. This would allow for about 675 children and 1050 adults to be evaluated each year for suitability for epilepsy surgery representing a 150% increase in pediatric epilepsy surgery evaluation and a 170% increase in adult epilepsy surgery evaluation. Epilepsy surgery was found to be cost-effective compared to continued medical management in children with drug-refractory epilepsy with the incremental cost-effectiveness ratio of $25,020 (Cdn) to $69,451 (Cdn) per QALY for 2 of the scenarios examined. In the case of choosing epilepsy surgery versus continued medical management in children known to be suitable for surgery, the epilepsy surgery was found to be less costly and provided greater clinical benefit, that is, it was the dominant strategy. Conclusion Epilepsy surgery for medically intractable epilepsy in suitable candidates has consistently been found to provide favourable clinical outcomes and has been demonstrated to be cost-effective in both adult and child patient populations. The first step to increasing access to epilepsy surgery is to provide access to evidence-based care for all patients with epilepsy, both adults and children, through the provision of resources to expand EMU bed capacity and associated clinical personnel across the province of Ontario. Plain Language Summary Epilepsy, characterized by recurrent, unpredictable, and spontaneous seizures, affects approximately 70,000 people in Ontario. About 30% continue to suffer from seizures despite using 2 or more anti-seizure medications. For these individuals epilepsy surgery is a treatment option to stop the seizures or at least reduce their frequency. Awareness of this treatment option is not widespread and people are not commonly referred to those hospitals in Ontario where this surgery is available. A proposal to increase access to epilepsy care and surgery has been made by an expert committee that provided a report to the Ontario Health Technology Advisory Committee (OHTAC). In order to address the lack of access of patients with medically intractable epilepsy to the possibility of curative surgical treatment, it is necessary to design a system that provides equal availability of evidence-based treatment for all epilepsy patients in Ontario, both adults and children. To this end, the establishment of district epilepsy care centres and the further development of the existing regional epilepsy care centres in the province have been proposed. This report outlines the estimated additional funds that will be required to implement the proposal. It also examines the cost-effectiveness of referral to these centres and epilepsy surgery. For the 21,000 people in the province with drug-refractory epilepsy, referral to an epilepsy monitoring unit (EMU) located at one of the epilepsy care centres is the first step to determining if epilepsy surgery is an option for them. The expert committee proposal suggests that the number of EMU beds be increased from the current 19 to 50 to allow for the assessment of those individuals with drug-refractory epilepsy. The health care system budget impact model presented in this report estimates that it would cost approximately $18 million (Cdn) each year over the next 5 years to increase the number of EMU beds and expand associated epilepsy care centres to permit the systematic evidence-based care of all Ontarians with epilepsy and evaluate more people for surgery candidacy. This amount would provide appropriate care for patients with epilepsy and ensure that about 675 children and 1050 adults could be assessed each year for suitability for epilepsy surgery. Surgery could then be made available to just over 300 people per year. Epilepsy surgery over the long term is a less expensive treatment alternative for adults and children with medically refractory epilepsy compared with continued drug treatment. In addition, drug treatment does not always work for some patients; nor does it necessarily provide improved quality of life. This report includes a cost-effectiveness analysis comparing referral for assessment for epilepsy surgery with continuing medical management in children with drug-refractory epilepsy. In all the cases examined epilepsy surgery provides good value for money over a 20-year period. Similar studies have found that the benefits from epilepsy surgery outweigh those of continuing medical management in adult patients with medically refractory epilepsy. PMID:23074428
Sitewide Environmental Assessment for the National Renewable Energy Laboratory, Golden, Colorado
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1993-05-04
The Solar Energy Research, Development, and Demonstration Act of 1974 authorized a federal program to develop solar energy as a viable source of the nation`s future energy needs. Under this authority, the National Renewable Energy Laboratory (NREL) was created as a laboratory of the Department of Energy (DOE) to research a number of renewable energy possibilities. The laboratory conducts its operations both in government-owned facilities on the NREL South Table Mountain (STM) Site near Golden, Colorado, and in a number of leased facilities, particularly the Denver West Office Park. NREL operations include research in energy technologies, and other areas ofmore » national environmental and energy technology interest. Examples of these technologies include electricity from sunlight with solar cells (photovoltaics); energy from wind (windmills or wind turbines); conversion of plants and plant products (biomass) into liquid fuels (ethanol and methanol); heat from the sun (solar thermal) in place of wood, oil, gas, coal and other forms of heating; and solar buildings. NREL proposes to continue and expand the present R&D efforts in C&R energy by making infrastructure improvements and constructing facilities to eventually consolidate the R&D and associated support activities at its STM Site. In addition, it is proposed that operations continue in current leased space at the present levels of activity until site development is complete. The construction schedule proposed is designed to develop the site as rapidly as possible, dependent on Congressional funding, to accommodate not only the existing R&D that is being conducted in leased facilities off-site but to also allow for the 20-year projected growth. Impacts from operations currently conducted off-site are quantified and added to the cumulative impacts of the STM site. This environmental assessment provides information to determine the severity of impacts on the environment from the proposed action.« less
ERIC Educational Resources Information Center
Wang, Tianyou
2008-01-01
Von Davier, Holland, and Thayer (2004) laid out a five-step framework of test equating that can be applied to various data collection designs and equating methods. In the continuization step, they presented an adjusted Gaussian kernel method that preserves the first two moments. This article proposes an alternative continuization method that…
A Continuous Identity Authentication Scheme Based on Physiological and Behavioral Characteristics.
Wu, Guannan; Wang, Jian; Zhang, Yongrong; Jiang, Shuai
2018-01-10
Wearable devices have flourished over the past ten years providing great advantages to people and, recently, they have also been used for identity authentication. Most of the authentication methods adopt a one-time authentication manner which cannot provide continuous certification. To address this issue, we present a two-step authentication method based on an own-built fingertip sensor device which can capture motion data (e.g., acceleration and angular velocity) and physiological data (e.g., a photoplethysmography (PPG) signal) simultaneously. When the device is worn on the user's fingertip, it will automatically recognize whether the wearer is a legitimate user or not. More specifically, multisensor data is collected and analyzed to extract representative and intensive features. Then, human activity recognition is applied as the first step to enhance the practicability of the authentication system. After correctly discriminating the motion state, a one-class machine learning algorithm is applied for identity authentication as the second step. When a user wears the device, the authentication process is carried on automatically at set intervals. Analyses were conducted using data from 40 individuals across various operational scenarios. Extensive experiments were executed to examine the effectiveness of the proposed approach, which achieved an average accuracy rate of 98.5% and an F1-score of 86.67%. Our results suggest that the proposed scheme provides a feasible and practical solution for authentication.
2015-01-01
To date, the Rare Cancer Network (RCN) has initiated more than 90 studies and 54 peer-reviewed publications were produced as a result. The Second International Symposium of the Rare Cancer Network recently took place in Istanbul, Turkey on April 17-18, 2015, and update was given on multiple currently ongoing projects, while also giving room for new proposals which will shape the direction of future studies for the group. This companion issue of the RCN Proceedings summarized the findings of this meeting, while also serving as a call for fresh projects and papers which will continue to energize the group and advance the oncologic science. A brief introduction to the principles, history, and vision of the RCN was also included. To review, the academic year of 2014-15 marked an enormous success for the international members of the RCN, with the generation of 8 fully published papers and more than 12 newly proposed topics. By the collective efforts of all RCN members, in the future, we look forward to the upcoming opportunities in continuing to advance the standard of chemo- and radiotherapeutic oncologic care for selected rare tumor topics. The studies of these rare cancers often do not allow the design and execution of prospectively enrolled trials; however, these uncommon malignancies do impact the humankind and add to its suffering globally in significant ways. PMID:26500735
A Continuous Identity Authentication Scheme Based on Physiological and Behavioral Characteristics
Wu, Guannan; Wang, Jian; Zhang, Yongrong; Jiang, Shuai
2018-01-01
Wearable devices have flourished over the past ten years providing great advantages to people and, recently, they have also been used for identity authentication. Most of the authentication methods adopt a one-time authentication manner which cannot provide continuous certification. To address this issue, we present a two-step authentication method based on an own-built fingertip sensor device which can capture motion data (e.g., acceleration and angular velocity) and physiological data (e.g., a photoplethysmography (PPG) signal) simultaneously. When the device is worn on the user’s fingertip, it will automatically recognize whether the wearer is a legitimate user or not. More specifically, multisensor data is collected and analyzed to extract representative and intensive features. Then, human activity recognition is applied as the first step to enhance the practicability of the authentication system. After correctly discriminating the motion state, a one-class machine learning algorithm is applied for identity authentication as the second step. When a user wears the device, the authentication process is carried on automatically at set intervals. Analyses were conducted using data from 40 individuals across various operational scenarios. Extensive experiments were executed to examine the effectiveness of the proposed approach, which achieved an average accuracy rate of 98.5% and an F1-score of 86.67%. Our results suggest that the proposed scheme provides a feasible and practical solution for authentication. PMID:29320463
Bölsterli Heinzle, Bigna Katrin; Bast, Thomas; Critelli, Hanne; Huber, Reto; Schmitt, Bernhard
2017-02-01
Epileptic encephalopathy with continuous spike-and-waves during sleep (CSWS) occurs during childhood and is characterized by an activation of spike wave complexes during slow wave sleep. The location of epileptic foci is variable, as is etiology. A relationship between the epileptic focus and age has been shown in various focal epilepsies following a posterior-anterior trajectory, and a link to brain maturation has been proposed. We hypothesize that in CSWS, maximal spike wave activity, corresponding to the epileptic focus, is related to age and shows a posterior-anterior evolution. In a retrospective cross-sectional study on CSWS (22 EEGs of 22 patients aged 3.1–13.5 years), the location of the epileptic focus is related to age and follows a posterior-anterior course. Younger patients are more likely to have posterior foci than older ones. We propose that the posterior-anterior trajectory of maximal spike waves in CSWS might reflect maturational changes of maximal expression of sleep slow waves, which follow a comparable course. Epileptic spike waves, that is, “hyper-synchronized slow waves” may occur at the place where the highest and therefore most synchronized slow waves meet brain tissue with an increased susceptibility to synchronization. Georg Thieme Verlag KG Stuttgart · New York.
45 CFR 1641.19 - Notice of proposed removal.
Code of Federal Regulations, 2010 CFR
2010-10-01
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45 CFR 1641.8 - Notice of proposed debarment.
Code of Federal Regulations, 2010 CFR
2010-10-01
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2010-07-01
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29 CFR 1690.305 - Nondisclosure of proposed issuances.
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2010-07-01
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29 CFR 1690.302 - Issuances proposed by EEOC.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 29 Labor 4 2012-07-01 2012-07-01 false Issuances proposed by EEOC. 1690.302 Section 1690.302 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES ON INTERAGENCY... EEOC. Whenever the EEOC proposes to develop a significant issuance or any issuance requiring...
29 CFR 1690.305 - Nondisclosure of proposed issuances.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 29 Labor 4 2013-07-01 2013-07-01 false Nondisclosure of proposed issuances. 1690.305 Section 1690.305 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES... discussion of these matters and expediting the coordination process, the EEOC will not discuss the proposed...
29 CFR 1690.302 - Issuances proposed by EEOC.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 29 Labor 4 2011-07-01 2011-07-01 false Issuances proposed by EEOC. 1690.302 Section 1690.302 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES ON INTERAGENCY... EEOC. Whenever the EEOC proposes to develop a significant issuance or any issuance requiring...
29 CFR 1690.302 - Issuances proposed by EEOC.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 29 Labor 4 2013-07-01 2013-07-01 false Issuances proposed by EEOC. 1690.302 Section 1690.302 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES ON INTERAGENCY... EEOC. Whenever the EEOC proposes to develop a significant issuance or any issuance requiring...
Life sciences recruitment objectives
NASA Technical Reports Server (NTRS)
Keefe, J. Richard
1992-01-01
The goals of the Life Sciences Division of the Office of Space Sciences and Application are to ensure the health, well being and productivity of humans in space and to acquire fundamental scientific knowledge in space life sciences. With these goals in mind Space Station Freedom represents substantial opportunities and significant challenges to the Life Sciences Division. For the first time it will be possible to replicate experimental data from a variety of simultaneously exposed species with appropriate controls and real-time analytical capabilities over extended periods of time. At the same time, a system for monitoring and ameliorating the physiological adaptations that occur in humans subjected to extended space flight must be evolved to provide the continuing operational support to the SSF crew. To meet its goals, and take advantage of the opportunities and overcome the challenges presented by Space Station Freedom, the Life Sciences Division is developing a suite of discipline-focused sequence. The research phase of the Life Sciences Space Station Freedom Program will commence with the utilization flights following the deployment of the U.S. laboratory module and achievement of Man Tended Capability. Investigators that want the Life Sciences Division to sponsor their experiment on SSF can do so in one of three ways: submitting a proposal in response to a NASA Research Announcement (NRA), submitting a proposal in response to an Announcement of Opportunity (AO), or submitting an unsolicited proposal. The scientific merit of all proposals will be evaluated by peer review panels. Proposals will also be evaluated based on relevance to NASA's missions and on the results of an Engineering and Cost Analyses. The Life Sciences Division expects that the majority of its funding opportunities will be announced through NRA's. It is anticipated that the first NRA will be released approximately three years before first element launch (currently scheduled for late 1995). Subsequent NRA's will be released on a rotating two year cycle.
Education of tobacco use prevention and cessation for dental professionals--a paradigm shift.
Davis, Joan M; Ramseier, Christoph A; Mattheos, Nikos; Schoonheim-Klein, Meta; Compton, Sharon; Al-Hazmi, Nadia; Polychronopoulou, Argy; Suvan, Jean; Antohé, Magda E; Forna, Doriana; Radley, Nicki
2010-02-01
The use of tobacco continues to be a substantial risk factor in the development and progression of oral cancer, periodontitis, implant failure and poor wound healing. Dental and dental hygiene education providers have made great advances towards the incorporation of tobacco education into their curricula in recent years. Unfortunately, however, both medical and dental education research has consistently reported schools providing only basic knowledge-based curricula that rarely incorporate more effective, behaviourally-based components affecting long-term change. The limited training of oral healthcare students, at least in part, is reflected in practising dental professionals continuing to report offering incomplete tobacco interventions. In order to prepare the next generation of oral healthcare providers, this paper proposes a paradigm shift in how tobacco use prevention and cessation (TUPAC) may be incorporated into existing curricula. It is suggested that schools should carefully consider: to what level of competency should TUPAC be trained in dental and dental hygiene schools; the importance of establishing rapport through good communication skills; the core knowledge level for TUPAC; suggested instructional and assessment strategies; the importance of continuing professional education for the enhancement of TUPAC.
Farias, Sarah Tomaszewski; Chand, Vineeta; Bonnici, Lisa; Baynes, Kathleen; Harvey, Danielle; Mungas, Dan; Simon, Christa; Reed, Bruce
2012-11-01
The Nun Study showed that lower linguistic ability in young adulthood, measured by idea density (ID), increased the risk of dementia in late life. The present study examined whether ID measured in late life continues to predict the trajectory of cognitive change. ID was measured in 81 older adults who were followed longitudinally for an average of 4.3 years. Changes in global cognition and 4 specific neuropsychological domains (episodic memory, semantic memory, spatial abilities, and executive function) were examined as outcomes. Separate random effects models tested the effect of ID on longitudinal change in outcomes, adjusted for age and education. Lower ID was associated with greater subsequent decline in global cognition, semantic memory, episodic memory, and spatial abilities. When analysis was restricted to only participants without dementia at the time ID was collected, results were similar. Linguistic ability in young adulthood, as measured by ID, has been previously proposed as an index of neurocognitive development and/or cognitive reserve. The present study provides evidence that even when ID is measured in old age, it continues to be associated with subsequent cognitive decline and as such may continue to provide a marker of cognitive reserve.
Car radiator burns: a prevention issue.
Rabbitts, Angela; Alden, Nicole E; Conlin, Tara; Yurt, Roger W
2004-01-01
Scald burns continue to be the major cause of injury to patients admitted to the burn center. Scald burns occurring from car radiator fluid comprise a significant subgroup. Although manufacturer warning labels have been placed on car radiators, these burns continue to occur. This retrospective review looks at all patients admitted to our burn center who suffered scald burns from car radiator fluid to assess the extent of this problem. During the study period, 86 patients were identified as having suffered scald burns as a result of contact with car radiator fluid. Seventy-one percent of the burn injuries occurred in the summer months. The areas most commonly burned were the head and upper extremities. Burn prevention efforts have improved greatly over the years; however, this study demonstrates that scald burns from car radiator fluid continue to cause physical, emotional, and financial devastation. The current radiator warning labels alone are not effective. The National Highway Traffic Safety Administration has proposed a new federal motor vehicle safety standard to aid in decreasing the number of scald burns from car radiators. The results of this study were submitted to the United States Department of Transportation for inclusion in a docket for federal legislation supporting these safety measures.
Santos, José António; Galante-Oliveira, Susana; Barroso, Carlos
2011-03-01
The current work presents an innovative statistical approach to model ordinal variables in environmental monitoring studies. An ordinal variable has values that can only be compared as "less", "equal" or "greater" and it is not possible to have information about the size of the difference between two particular values. The example of ordinal variable under this study is the vas deferens sequence (VDS) used in imposex (superimposition of male sexual characters onto prosobranch females) field assessment programmes for monitoring tributyltin (TBT) pollution. The statistical methodology presented here is the ordered logit regression model. It assumes that the VDS is an ordinal variable whose values match up a process of imposex development that can be considered continuous in both biological and statistical senses and can be described by a latent non-observable continuous variable. This model was applied to the case study of Nucella lapillus imposex monitoring surveys conducted in the Portuguese coast between 2003 and 2008 to evaluate the temporal evolution of TBT pollution in this country. In order to produce more reliable conclusions, the proposed model includes covariates that may influence the imposex response besides TBT (e.g. the shell size). The model also provides an analysis of the environmental risk associated to TBT pollution by estimating the probability of the occurrence of females with VDS ≥ 2 in each year, according to OSPAR criteria. We consider that the proposed application of this statistical methodology has a great potential in environmental monitoring whenever there is the need to model variables that can only be assessed through an ordinal scale of values.
Tilly, Jonathan L; Niikura, Yuichi; Rueda, Bo R
2009-01-01
Whether or not oogenesis continues in the ovaries of mammalian females during postnatal life was heavily debated from the late 1800s through the mid-1900s. However, in 1951 Lord Solomon Zuckerman published what many consider to be a landmark paper summarizing his personal views of data existing at the time for and against the possibility of postnatal oogenesis. In Zuckerman's opinion, none of the evidence he considered was inconsistent with Waldeyer's initial proposal in 1870 that female mammals cease production of oocytes at or shortly after birth. This conclusion rapidly became dogma, and remained essentially unchallenged until just recently, despite the fact that Zuckerman did not offer a single experiment proving that adult female mammals are incapable of oogenesis. Instead, 20 years later he reemphasized that his conclusion was based solely on an absence of data he felt would be inconsistent with the idea of a nonrenewable oocyte pool provided at birth. However, in the immortal words of Carl Sagan, an "absence of evidence is not evidence of absence." Indeed, building on the efforts of a few scientists who continued to question this dogma after Zuckerman's treatise in 1951, we reported several data sets in 2004 that were very much inconsistent with the widely held belief that germ cell production in female mammals ceases at birth. Perhaps not surprisingly, given the magnitude of the paradigm shift being proposed, this work reignited a vigorous debate that first began more than a century ago. Our purpose here is to review the experimental evidence offered in recent studies arguing support for and against the possibility that adult mammalian females replenish their oocyte reserve. "Never discourage anyone who continually makes progress, no matter how slow."-Plato (427-347 BC).
Downward continuation of airborne gravity data by means of the change of boundary approach
NASA Astrophysics Data System (ADS)
Mansi, A. H.; Capponi, M.; Sampietro, D.
2018-03-01
Within the modelling of gravity data, a common practice is the upward/downward continuation of the signal, i.e. the process of continuing the gravitational signal in the vertical direction away or closer to the sources, respectively. The gravity field, being a potential field, satisfies the Laplace's equation outside the masses and this means that it allows to unambiguously perform this analytical continuation only in a source-free domain. The analytical continuation problem has been solved both in the space and spectral domains by exploiting different algorithms. As well known, the downward continuation operator, differently from the upward one, is an unstable operator, due to its spectral characteristics similar to those of a high-pass filter, and several regularization methods have been proposed in order to stabilize it. In this work, an iterative procedure to downward/upward continue the gravity field observations, acquired at different altitudes, is proposed. This methodology is based on the change of boundary principle and it has been expressively thought for aerogravimetric observations for geophysical exploration purposes. Within this field of application, usually several simplifications can be applied, basically due to the specific characteristics of the airborne surveys which are usually flown at almost constant altitude as close as possible to the terrain. For instance, these characteristics, as shown in the present work, allow to perform the downward continuation without the need of any regularization. The goodness of the proposed methodology has been evaluated by means of a numerical test on real data, acquired in the South of Australia. The test shows that it is possible to move the aerogravimetric data, acquired along tracks with a maximum height difference of about 250 m, with accuracies of the order of 10^{-3} mGal.
Some Statistics for Assessing Person-Fit Based on Continuous-Response Models
ERIC Educational Resources Information Center
Ferrando, Pere Joan
2010-01-01
This article proposes several statistics for assessing individual fit based on two unidimensional models for continuous responses: linear factor analysis and Samejima's continuous response model. Both models are approached using a common framework based on underlying response variables and are formulated at the individual level as fixed regression…
14 CFR 302.211 - Procedures in certificate cases involving initial or continuing fitness.
Code of Federal Regulations, 2012 CFR
2012-01-01
... initial or continuing fitness. 302.211 Section 302.211 Aeronautics and Space OFFICE OF THE SECRETARY... Disposition of Applications § 302.211 Procedures in certificate cases involving initial or continuing fitness... applicant's fitness to operate. Where such applications propose the operation of scheduled service in...
14 CFR 302.211 - Procedures in certificate cases involving initial or continuing fitness.
Code of Federal Regulations, 2014 CFR
2014-01-01
... initial or continuing fitness. 302.211 Section 302.211 Aeronautics and Space OFFICE OF THE SECRETARY... Disposition of Applications § 302.211 Procedures in certificate cases involving initial or continuing fitness... applicant's fitness to operate. Where such applications propose the operation of scheduled service in...
14 CFR 302.211 - Procedures in certificate cases involving initial or continuing fitness.
Code of Federal Regulations, 2013 CFR
2013-01-01
... initial or continuing fitness. 302.211 Section 302.211 Aeronautics and Space OFFICE OF THE SECRETARY... Disposition of Applications § 302.211 Procedures in certificate cases involving initial or continuing fitness... applicant's fitness to operate. Where such applications propose the operation of scheduled service in...
14 CFR 302.211 - Procedures in certificate cases involving initial or continuing fitness.
Code of Federal Regulations, 2010 CFR
2010-01-01
... initial or continuing fitness. 302.211 Section 302.211 Aeronautics and Space OFFICE OF THE SECRETARY... Disposition of Applications § 302.211 Procedures in certificate cases involving initial or continuing fitness... applicant's fitness to operate. Where such applications propose the operation of scheduled service in...
14 CFR 302.211 - Procedures in certificate cases involving initial or continuing fitness.
Code of Federal Regulations, 2011 CFR
2011-01-01
... initial or continuing fitness. 302.211 Section 302.211 Aeronautics and Space OFFICE OF THE SECRETARY... Disposition of Applications § 302.211 Procedures in certificate cases involving initial or continuing fitness... applicant's fitness to operate. Where such applications propose the operation of scheduled service in...
Continuous and difficult discrete cognitive tasks promote improved stability in older adults.
Lajoie, Yves; Jehu, Deborah A; Richer, Natalie; Chan, Alan
2017-06-01
Directing attention away from postural control and onto a cognitive task affords the emergence of automatic control processes. Perhaps the continuous withdrawal of attention from the postural task facilitates an automatization of posture as opposed to only intermittent withdrawal; however this is unknown in the aging population. Twenty older adults (69.9±3.5years) stood with feet together on a force platform for 60s while performing randomly assigned discrete and continuous cognitive tasks. Participants were instructed to stand comfortably with their arms by their sides while verbally responding to the auditory stimuli as fast as possible during the discrete tasks, or mentally performing the continuous cognitive tasks. Participants also performed single-task standing. Results demonstrate significant reductions in sway amplitude and sway variability for the difficult discrete task as well as the continuous tasks relative to single-task standing. The continuous cognitive tasks also prompted greater frequency of sway in the anterior-posterior direction compared to single-standing and discrete tasks, and greater velocity in both directions compared to single-task standing, which could suggest ankle stiffening. No differences in the simple discrete condition were shown compared to single-task standing, perhaps due to the simplicity of the task. Therefore, we propose that the level of difficulty of the task, the specific neuropsychological process engaged during the cognitive task, and the type of task (discrete vs. continuous) influence postural control in older adults. Dual-tasking is a common activity of daily living; this work provides insight into the age-related changes in postural stability and attention demand. Copyright © 2017 Elsevier B.V. All rights reserved.
Hall, Amanda K; Backonja, Uba; Painter, Ian; Cakmak, Maya; Sung, Minjung; Lau, Timothy; Thompson, Hilaire J; Demiris, George
2017-11-29
As the number of older adults living with chronic conditions continues to rise, they will require assistance with activities of daily living (ADL) and healthcare tasks to continue living independently in their homes. One proposed solution to assist with the care needs of an aging population and a shrinking healthcare workforce is robotic technology. Using a cross-sectional survey design, we purposively sampled adults (≥18 years old) to assess generational acceptance and perceived usefulness of robots to assist with ADLs, healthcare tasks, and evaluate acceptance of robotic healthcare assistance across different settings. A total of 499 adults (age range [years] 18-98, Mean = 38.7, SD = 22.7) responded to the survey. Significant differences were found among young, middle-aged, and older adults on perceived usefulness of robots for cleaning, escorting them around town, acting as companionship, delivering meals, assessing sadness and calling for help, providing medical advice, taking vital sign assessments, and assisting with personal care (p < 0.05). The majority of younger adults reported that they would like a robot to provide healthcare assistance in the hospital, compared to middle-aged and older adults (p < 0.001). Results of this study can guide the design of robots to assist adults of all ages with useful tasks.
Nevada Test Site-Directed Research and Development, FY 2007 Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wil Lewis, editor
2008-02-20
The Nevada Test Site-Directed Research and Development (SDRD) program completed a very successful year of research and development activities in FY 2007. Twenty-nine new projects were selected for funding this year, and eight projects started in FY 2006 were brought to conclusion. The total funds expended by the SDRD program were $5.67 million, for an average per-project cost of $153 thousand. An external audit conducted in September 2007 verified that appropriate accounting practices were applied to the SDRD program. Highlights for the year included: programmatic adoption of 8 SDRD-developed technologies; the filing of 9 invention disclosures for innovation evolving frommore » SDRD projects; participation in the tri-Lab Laboratory Directed Research and Development (LDRD) and SDRD Symposium that was broadly attended by Nevada Test Site (NTS), National Nuclear Security Administration (NNSA), LDRD, U.S. Department of Homeland Security (DHS), and U.S. Department of Defense (DoD) representatives; peer reviews of all FY 2007 projects; and the successful completion of 37 R&D projects, as presented in this report. In response to a company-wide call, authors throughout the NTS complex submitted 182 proposals for FY 2007 SDRD projects. The SDRD program has seen a dramatic increase in the yearly total of submitted proposals--from 69 in FY 2002 to 182 this year--while the number of projects funded has actually decreased from a program high of 57 in FY 2004. The overall effect of this trend has helped ensure an increasingly competitive program that benefited from a broader set of innovative ideas, making project selection both challenging and rewarding. Proposals were evaluated for technical merit, including such factors as innovation, probability of success, potential benefit, and mission applicability. Authors and reviewers benefited from the use of a shortfalls list entitled the 'NTS Technology Needs Assessment' that was compiled from NTS, National Weapons Laboratory (NWL), and NNSA sources. This tool continues to be of considerable value in aligning the SDRD program with mission priorities, and was expanded in FY 2007 to include technology development needs from the DHS and other agencies with missions closely aligned to that of the NTS.« less
40 CFR 135.5 - Service of proposed consent judgment.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Service of proposed consent judgment. 135.5 Section 135.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.5 Service of proposed...
40 CFR 135.5 - Service of proposed consent judgment.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Service of proposed consent judgment. 135.5 Section 135.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.5 Service of proposed...
40 CFR 135.5 - Service of proposed consent judgment.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Service of proposed consent judgment. 135.5 Section 135.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.5 Service of proposed...
40 CFR 135.5 - Service of proposed consent judgment.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Service of proposed consent judgment. 135.5 Section 135.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.5 Service of proposed...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-07
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45 CFR 672.19 - Proposed findings, conclusions, and order.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 3 2014-10-01 2014-10-01 false Proposed findings, conclusions, and order. 672.19 Section 672.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... otherwise ordered by the Presiding Officer, any party may submit proposed findings of fact, conclusions of...
45 CFR 672.19 - Proposed findings, conclusions, and order.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 3 2010-10-01 2010-10-01 false Proposed findings, conclusions, and order. 672.19 Section 672.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... otherwise ordered by the Presiding Officer, any party may submit proposed findings of fact, conclusions of...
45 CFR 672.19 - Proposed findings, conclusions, and order.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 3 2013-10-01 2013-10-01 false Proposed findings, conclusions, and order. 672.19 Section 672.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... otherwise ordered by the Presiding Officer, any party may submit proposed findings of fact, conclusions of...
45 CFR 672.19 - Proposed findings, conclusions, and order.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 3 2011-10-01 2011-10-01 false Proposed findings, conclusions, and order. 672.19 Section 672.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... otherwise ordered by the Presiding Officer, any party may submit proposed findings of fact, conclusions of...
45 CFR 672.19 - Proposed findings, conclusions, and order.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 3 2012-10-01 2012-10-01 false Proposed findings, conclusions, and order. 672.19 Section 672.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... otherwise ordered by the Presiding Officer, any party may submit proposed findings of fact, conclusions of...
7 CFR 3405.11 - Content of a proposal.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION...) The title of the project shown on the “Higher Education Proposal Cover Page” must be brief (80... institution, the targeted need area(s), and the title of the proposal must be identified exactly as shown on...
Code of Federal Regulations, 2014 CFR
2014-01-01
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Code of Federal Regulations, 2011 CFR
2011-01-01
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7 CFR 3405.12 - Intent to submit a proposal.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 15 2012-01-01 2012-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...
7 CFR 3405.12 - Intent to submit a proposal.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 15 2013-01-01 2013-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...
7 CFR 3405.12 - Intent to submit a proposal.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 15 2014-01-01 2014-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...
7 CFR 3405.12 - Intent to submit a proposal.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 15 2011-01-01 2011-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...
Theory-led confirmation bias and experimental persona
NASA Astrophysics Data System (ADS)
Allen, Michael
2011-04-01
Questionnaire and interview findings from a survey of three Year 8 (ages 12-13 years) science practical lessons (n = 52) demonstrate how pupils' data collection and inference making were sometimes biased by desires to confirm a personal theory. A variety of behaviours are described where learners knowingly rejected anomalies, manipulated apparatus, invented results or carried out other improper operations to either collect data which they believed were scientifically correct, or achieve social conformity. It is proposed that confirmation bias was a consequence of the degree to which individuals were laden by theory, and driven by this, experimenters assumed one of three different personas: becoming right answer confirmers; good scientists; or indifferent spectators. These personas have parallels with historical instances of scientific behaviour. Implications of a continued teacher-tolerance of pupil confirmation bias include the promotion of unscientific experimenting, and the persistence of unchallenged science misconceptions. Solutions are offered in the way of practical strategies that might reduce experimenters' theory-ladeness.
Whitelaw, C Bruce A; Joshi, Akshay; Kumar, Satish; Lillico, Simon G; Proudfoot, Chris
2016-02-01
It has been thirty years since the first genetically engineered animal with altered milk composition was reported. During the intervening years, the world population has increased from 5bn to 7bn people. An increasing demand for protein in the human diet has followed this population expansion, putting huge stress on the food supply chain. Many solutions to the grand challenge of food security for all have been proposed and are currently under investigation and study. Amongst these, genetics still has an important role to play, aiming to continually enable the selection of livestock with enhanced traits. Part of the geneticist's tool box is the technology of genetic engineering. In this Invited Review, we indicate that this technology has come a long way, we focus on the genetic engineering of dairy animals and we argue that the new strategies for precision breeding demand proper evaluation as to how they could contribute to the essential increases in agricultural productivity our society must achieve.
Observatory Science with the NICER X-ray Timing Instrument
NASA Astrophysics Data System (ADS)
Remillard, Ronald A.
2016-04-01
This presentation is submitted on behalf of the NICER Observatory Science Working Group. NICER will be deployed on the International Space Station later in 2016. The X-ray sensitivity spans 0.2-12 keV, with CCD-like spectral resolution, low background rates, and unprecedented timing accuracy. A Guest Observer (GO) Program has been approved by NASA as one of the proposed Science Enhancement Options, contingent on NICER meeting its Prime Mission Science Objectives. The NICER Science team will observe limited Observatory Science targets (i.e., sources other than neutron stars) in year 1, and GO observations will constitute 50% of the exposures in year 2. Thereafter, NICER will compete for continuation via the NASA Senior Review process. NICER Instrument performance is compared with Missions such as XMM-Newton and RXTE. We briefly highlight the expected themes for Observatory Science relating to accreting black holes on all mass scales, magnetic CVs, active stars, and clusters of galaxies.
Wright, Alexandra J; Ebeling, Anne; de Kroon, Hans; Roscher, Christiane; Weigelt, Alexandra; Buchmann, Nina; Buchmann, Tina; Fischer, Christine; Hacker, Nina; Hildebrandt, Anke; Leimer, Sophia; Mommer, Liesje; Oelmann, Yvonne; Scheu, Stefan; Steinauer, Katja; Strecker, Tanja; Weisser, Wolfgang; Wilcke, Wolfgang; Eisenhauer, Nico
2015-01-20
The natural world is increasingly defined by change. Within the next 100 years, rising atmospheric CO₂ concentrations will continue to increase the frequency and magnitude of extreme weather events. Simultaneously, human activities are reducing global biodiversity, with current extinction rates at ~1,000 × what they were before human domination of Earth's ecosystems. The co-occurrence of these trends may be of particular concern, as greater biological diversity could help ecosystems resist change during large perturbations. We use data from a 200-year flood event to show that when a disturbance is associated with an increase in resource availability, the opposite may occur. Flooding was associated with increases in productivity and decreases in stability, particularly in the highest diversity communities. Our results undermine the utility of the biodiversity-stability hypothesis during a large number of disturbances where resource availability increases. We propose a conceptual framework that can be widely applied during natural disturbances.
Van Sonsbeek, H M; Beeftink, H H; Tramper, J
1993-09-01
The application of two liquid phases that are poorly miscible is a fascinating research topic for biocatalytical conversions because of the promising results. Motives for application include an increase of productivity and achievement of continuous processing, but new limitations arise, e.g., interfacial effects such as biocatalyst accumulation and loss of activity, medium component accumulation, and slow coalescence. Centrifuges, membranes, and immobilization are tools that can overcome part of the problems, but more fundamental knowledge about interfaces and coalescence is still necessary for successful application. For scaleup and further development of processes based on the obtained results, a choice must be made for the configuration of the experimental setup of a bioreactor. Aspects like aeration, shear stress, batch or continuous processing, and immobilization can play an important role. This review article describes these aspects and the proposals that have been made in recent years concerning two-liquid-phase bioreactors. It shows some adaptations to existing bioreactors, such as loop reactors and stirred-tank reactors.
Nuclear cardiology: Myocardial perfusion and function
DOE Office of Scientific and Technical Information (OSTI.GOV)
Seldin, D.W.
1991-08-01
Myocardial perfusion studies continue to be a major focus of research, with new investigations of the relationship of exercise-redistribution thallium imaging to diagnosis, prognosis, and case management. The redistribution phenomenon, which seemed to be fairly well understood a few years ago, is now recognized to be much more complex than originally thought, and various strategies have been proposed to clarify the meaning of persistent defects. Pharmacologic intervention with dipyridamole and adenosine has become available as an alternative to exercise, and comparisons with exercise imaging and catheterization results have been described. Thallium itself is no longer the sole single-photon perfusion radiopharmaceutical;more » two new technetium agents are now widely available. In addition to perfusion studies, advances in the study of ventricular function have been made, including reports of studies performed in conjunction with technetium perfusion studies, new insights into cardiac physiology, and the prognostic and case-management information that function studies provide. Finally, work has continued with monoclonal antibodies for the identification of areas of myocyte necrosis. 41 references.« less
Wang, Tianyun; Lu, Xinfei; Yu, Xiaofei; Xi, Zhendong; Chen, Weidong
2014-01-01
In recent years, various applications regarding sparse continuous signal recovery such as source localization, radar imaging, communication channel estimation, etc., have been addressed from the perspective of compressive sensing (CS) theory. However, there are two major defects that need to be tackled when considering any practical utilization. The first issue is off-grid problem caused by the basis mismatch between arbitrary located unknowns and the pre-specified dictionary, which would make conventional CS reconstruction methods degrade considerably. The second important issue is the urgent demand for low-complexity algorithms, especially when faced with the requirement of real-time implementation. In this paper, to deal with these two problems, we have presented three fast and accurate sparse reconstruction algorithms, termed as HR-DCD, Hlog-DCD and Hlp-DCD, which are based on homotopy, dichotomous coordinate descent (DCD) iterations and non-convex regularizations, by combining with the grid refinement technique. Experimental results are provided to demonstrate the effectiveness of the proposed algorithms and related analysis. PMID:24675758
Dislodgement of variceal bands after esophageal balloon tamponade for variceal bleeding.
Mogrovejo, Estela; Manickam, Palaniappan; Polidori, Gregg; Cappell, Mitchell S
2014-01-01
A 43-year-old male with alcoholic cirrhosis underwent EGD for hematemesis which revealed bleeding, grade II, lower esophageal varices that were endoscopically ligated with 6 bands. All the bands remained attached to varices at the completion of EGD. Despite apparent initial hemostasis, balloon tamponade was performed one hour later for suspected continued bleeding. Due to suspected continuing bleeding, EGD was repeated 4 h after initial EGD, and 3 h after balloon tamponade. This EGD revealed the esophageal varices; none of the bands remaining on esophageal mucosa; multiple mucosal stigmata likely from trauma at initial site of variceal bands before dislodgement; and 3 dislodged bands in gastric body, duodenal bulb, or descending duodenum. The patient expired 17 h thereafter from hypovolemic shock. This single report may suggest an apparently novel, balloon tamponade complication: dislodgement of previously placed, endoscopic bands. The proposed pathophysiology is release of bands by stretching entrapped, esophageal mucosa during esophageal balloon tamponade. This complication, if confirmed, might render balloon tamponade a less desirable option very soon after band ligation.
State-of-the-art of alkaline rechargeable batteries
NASA Astrophysics Data System (ADS)
Morioka, Y.; Narukawa, S.; Itou, T.
Alkaline rechargeable batteries represented by Ni-Cd and Ni-MH batteries are expanding their market, continuously meeting an increasing demand. Approximately 30 years have elapsed since the first sealed Ni-Cd battery was commercialized for consumer use, and the production of these alkaline batteries is still expanding. The high power performance and good cost performance of these batteries are the outstanding features, which are leading to new battery applications. Continuous R&D of many researchers and engineers has improved these features. Since first coming to the market in 1990, Ni-MH batteries have been extending their application as power sources for portable advanced information and communication equipment. Improvements in electrode materials and other components have increased the energy density of current Ni-MH batteries to values of 91 Wh/kg and 340 Wh/l. Recently, novel metallic alloys for hydrogen storage have been proposed to increase their capacity further, and further improvement in the performance of these batteries is expected.
Wang, Xuefeng; Lee, Seunggeun; Zhu, Xiaofeng; Redline, Susan; Lin, Xihong
2013-12-01
Family-based genetic association studies of related individuals provide opportunities to detect genetic variants that complement studies of unrelated individuals. Most statistical methods for family association studies for common variants are single marker based, which test one SNP a time. In this paper, we consider testing the effect of an SNP set, e.g., SNPs in a gene, in family studies, for both continuous and discrete traits. Specifically, we propose a generalized estimating equations (GEEs) based kernel association test, a variance component based testing method, to test for the association between a phenotype and multiple variants in an SNP set jointly using family samples. The proposed approach allows for both continuous and discrete traits, where the correlation among family members is taken into account through the use of an empirical covariance estimator. We derive the theoretical distribution of the proposed statistic under the null and develop analytical methods to calculate the P-values. We also propose an efficient resampling method for correcting for small sample size bias in family studies. The proposed method allows for easily incorporating covariates and SNP-SNP interactions. Simulation studies show that the proposed method properly controls for type I error rates under both random and ascertained sampling schemes in family studies. We demonstrate through simulation studies that our approach has superior performance for association mapping compared to the single marker based minimum P-value GEE test for an SNP-set effect over a range of scenarios. We illustrate the application of the proposed method using data from the Cleveland Family GWAS Study. © 2013 WILEY PERIODICALS, INC.
Arctic Sea Ice Structure and Texture over Four Decades Using Landsat Archive Data
NASA Astrophysics Data System (ADS)
Doulgeris, A. P.; Scambos, T.; Tiampo, K. F.
2017-12-01
Arctic sea ice cover is a sensitive indicator of Arctic climate change, and has shown dramatic changes in recent decades, having thinned by 70% ( 3.5 m to 1.2 m between 1980 and 2015). Age distribution of the ice has changed in a similar fashion, with over 90% of the ice older than 5 winters now lost relative to 1985. To date, most of the data have been based on the continuous passive microwave record that began in 1978, which has 25 km grid resolution, or on SAR imagery with somewhat less frequent, less continuous observations. Landsat image data exist for the Arctic sea ice region north of Alaska and the MacKenzie River Delta area in Canada, the Canadian Archipelago, and Baffin Bay, extending back over 40 years. Resolution of the earliest Landsat MSS data is 56-70 m per pixel, and after 1984 many additional images at 30 m resolution are available. This 40+ year time period is used to investigate long-term changes in sea ice properties, such as comparing image-based snapshots with the trend in seasonal extents today, as well as more novel properties like sea ice roughness, lead structure and texture. The proposed study will initially investigate Landsat image analysis techniques to extract quantitative measures of ice roughness, lead fraction and perhaps morphological measures like lead linearity (which potentially indicate strength and compression history within the ice), and to explore these measures over the 40+ year time frame.
A critical review of existing innovative science and drilling proposals within IODP
NASA Astrophysics Data System (ADS)
Behrmann, J. H.
2009-04-01
In the present phase of the Integrated Ocean Drilling Program (IODP) activities are guided by the Initial Science Plan that identified three major themes: The Deep Biosphere and the Subseafloor Ocean; Environmental Change, Processes and Effects; and Solid Earth Cycles and Geodynamics. New initiatives and complex drilling proposals were developed that required major advances in drilling platforms and technologies, and expansion of the drilling community into new areas of specialization. The guiding themes in the Initial Science Plan are instrumental for the proposal development and evaluation, and will continue to represent the goals of IODP until 2013. A number of innovative and highly ranked individual proposals and coordinated sets of proposals ready to be drilled has been forwarded by the Science Planning Committee (SPC) to the IODP Operations Task Force (OTF) for scoping, planning and scheduling. For the Deep Biosphere theme these include proposals to drill targets in the Central Atlantic, the Okinawa Trough, and the Southern Pacific. The Environmental Change, Processes and Effects theme is proposed to - among others - be studied by a coordinated approach regarding the Southeast Asian Monsoon, but also by proposals addressing sdimentation, facies evolution and the paleoclimate record in the Atlantic and Indian Oceans. The Solid Earth Cycles and Geodynamics theme is represented by several proposals addressing subduction processes, seismogenesis, and oceanic crust formation mainly in the Pacific. Some of these have shaped drilling programs that are already in the process of being carried out, such as drilling in the Nankai Trough off Japan (the NantroSEIZE project), or drilling in oceanic crust created in a superfast spreading environment in the Eastern Pacific. There are many remaining issues to be addressed, and drilling programs to be completed before the end of the present phase of IODP in 2013. Planning of expeditions needs to be done in such a way that a balance between risk, cost, and scientific impact is achieved. At least part of the dilling also is required to be a necessary precursor for future investigations in coming phases of Ocean Drilling. Presently IODP faces the challenges of tight budgetary constraints, increasing operating costs of their platforms, and the need to develop drilling schedules that allow off-contract work of the R/V Chikyu and R/V Joides Resolution drilling vessels. Chikyu will operate within IODP for an average of 7 months per year over a 5-year period with the goals of achieving major milestones in NantroSEIZE, maximizing the use of the vessel for riser drilling, and start a new IODP project that requires riser drilling. Joides Resolution will also operate an average of 7 months per year with the goal of optimizing operating days within the restrictions imposed by the prioritized science. Mission Specific Platform expeditions will be carried out once every two years on average, with the goal of pioneering drilling in new, challenging environments. For the first time in IODP history, operations of Chikyu, Joides Resolution and Mission Specific Platform expeditions will be conducted simultaneously in 2009. This new phase of operations provides an unprecedented chance of progress in scientific ocean drilling.
Efficiency of workplace surveys conducted by Finnish occupational health services.
Savinainen, Minna; Oksa, Panu
2011-07-01
In Finland, workplace surveys are used to identify and assess health risks and problems caused by work and make suggestions for continuous improvement of the work environment. With the aid of the workplace survey, occupational health services can be tailored to a company. The aims of this study were to determine how occupational health professionals gather data via the workplace survey and the effect survey results have on companies. A total of 259 occupational health nurses and 108 occupational health physicians responded to the questionnaire: 84.2% were women and 15.8% were men. The mean age of the respondents was 48.8 years (range, 26 to 65 years). Usually occupational health nurses and foremen and sometimes occupational health physicians and occupational safety and health representatives initiate the workplace survey. More than 90% of the surveys were followed by action proposals, and about 50% of these were implemented. The proposals implemented most often concerned personal protective equipment and less often leadership. Survey respondents should have both the opportunity and the authority to affect resources, the work environment, work arrangements, and tools. Teamwork among occupational health and safety professionals, management, and employees is vital for cost-effectively solving today's complex problems at workplaces around the globe. Copyright 2011, SLACK Incorporated.