10 CFR 1044.10 - Will your identity be protected?

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Will your identity be protected? 1044.10 Section 1044.10... SECTION 3164 OF THE NATIONAL DEFENSE AUTHORIZATION ACT FOR FISCAL YEAR 2000 § 1044.10 Will your identity..., consistent with legal requirements, your identity and any information about your disclosure. [66 FR 4642, Jan...

10 CFR 1044.10 - Will your identity be protected?

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Will your identity be protected? 1044.10 Section 1044.10... SECTION 3164 OF THE NATIONAL DEFENSE AUTHORIZATION ACT FOR FISCAL YEAR 2000 § 1044.10 Will your identity..., consistent with legal requirements, your identity and any information about your disclosure. [66 FR 4642, Jan...

Opening remarks: welcome to the Allegheny National Forest; but will we be here 10 years from now?

Treesearch

John E. Palmer

1997-01-01

In our day-to-day struggles, we must keep our eyes on what is going on. The bottomline questions are, will we be harvesting timber 10 years from now, or will the Forest Service as an agency even exist 10 years from now? The author is not optimistic, but still holds some hope. That hope is in silviculturists and others who are willing to step forward and speak out....

7 CFR 1212.10 - Honey products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Honey products. 1212.10 Section 1212.10 Agriculture..., Consumer Education, and Industry Information Order Definitions § 1212.10 Honey products. “Honey products” mean products where honey is a principal ingredient. For purposes of this subpart, a product shall be...

Characteristics of Four-years of GOSAT/TANSO-FTS TIR V1.0 CO2 and CH4 Products

NASA Astrophysics Data System (ADS)

Saitoh, N.; Kimoto, S.; Sugimura, R.; Imasu, R.; Shiomi, K.; Kuze, A.; Kataoka, F.; Knuteson, R. O.; Machida, T.; Sawa, Y.; Matsuda, H.

2015-12-01

Greenhouse Gases Observing Satellite (GOSAT) was launched on 23 January 2009, and has continued to make global observations, including both nadir and off-nadir measurements, for more than six years since its launch. The thermal infrared (TIR) band of Thermal and Near-infrared Sensor for Carbon Observation Fourier Transform Spectrometer (TANSO-FTS) on board the GOSAT has observed CO2 and CH4 profiles. We have analyzed the four-year data from 2010 through 2013 of the latest released version of the TIR Level 2 (L2) CO2 and CH4 products (V1.0). Comparisons of the TIR upper atmospheric CO2 product with CO2 data from Comprehensive Observation Network for Trace Gases by Airliner (CONTRAIL) aircraft measurements show that the growth rate estimated from the TIR CO2 data is slightly lower than that from the CONTRAIL data. Overall, the TIR V1.0 CO2 product has better quality in the upper troposphere and lower stratosphere than the a priori judging from comparisons with the collocated aircraft data. In spring and summer, however, the quality of the TIR L2 CO2 products became slightly worse than in the other seasons, especially in the low and northern-mid latitudes. This is because the corresponding a priori had a larger bias and the TIR Level 1B (L1B) radiance spectra might have a larger bias in the spring-summer seasons. Here, we have tested several types of correction methods to modify the L1B spectral bias, and then compared CO2 and CH4 concentrations retrieved after applying spectral bias correction factors with coincident CONTRAIL and HIAPER Pole-to-Pole Observation (HIPPO) aircraft data. The comparison results suggest that the L1B spectral bias correction factor should be changed depending on wavelength. In addition, it should be expressed as a function of on-board internal calibration blackbody temperatures. This is because they are weak season-dependent parameters; they were clearly lower in spring and summer.

2007-2017: 10 years of IASI CO retrievals

NASA Astrophysics Data System (ADS)

George, M.; Clerbaux, C.; Hadji-Lazaro, J.; Pierre-Francois, C.; Hurtmans, D.; Edwards, D. P.; Worden, H. M.; Deeter, M. N.; Mao, D.; August, T.; Crapeau, M.

2017-12-01

Carbon monoxide (CO) is an important trace gas for understanding air quality and atmospheric composition. It is a good tracer of pollution plumes and atmospheric dynamics. IASI CO concentrations are retrieved from the radiance data using the Fast Operational Retrievals on Layers for IASI (FORLI) algorithm, based on the Optimal Estimation theory. The operational production is performed at EUMETSAT and the products are distributed in NRT via EUMETCast under the AC SAF auspices. We present here an analysis of 10 years of global distributions of CO. Improvements of the last FORLI-CO version (v20151001) will be shown. Updates in the auxiliary parameters (temperature, cloud information) have an impact on the retrieved product. Comparison with MOPITT CO data (v7T, record starting in 2000) was performed, both for partial and total columns. Harmonizing IASI and MOPITT CO products is challenging: a method using corrective factors (developed in the framework of the QA4ECV project) will be presented.

In situ 10Be-26Al exposure ages at Meteor Crater, Arizona

USGS Publications Warehouse

Nishiizumi, K.; Kohl, C.P.; Shoemaker, E.M.; Arnold, J.R.; Klein, J.; Fink, D.; Middleton, R.

1991-01-01

A new method of dating the surface exposure of rocks from in situ production of 10Be and 26Al has been applied to determine the age of Meteor Crater, Arizona. A lower bound on the crater age of 49,200 ?? 1,700 years has been obtained by this method. ?? 1991.

Six-year beechnut production in New Hampshire

Treesearch

William B. Leak; Raymond E. Graber; Raymond E. Graber

1993-01-01

Beechnut production and losses were studied over a 6-year period in 41 northern hardwood stands ranging in age from 10 to 140 years in the White Mountains of New Hampshire. Beechnut production increased consistently with stand age or d.b.h. of dominant trees and percentage of basal area composed of beech. Losses to insects, rodents, and birds before the seed reached...

Assessing soil fluxes using meteoric 10Be: development and application of the Be2D model

NASA Astrophysics Data System (ADS)

Campforts, Benjamin; Govers, Gerard; Vanacker, Veerle; Baken, Stijn; Smolders, Erik; Vanderborght, Jan

2015-04-01

Meteoric 10Be is a promising and increasingly popular tool to better understand soil fluxes at different timescales. Unlike other, more classical, methods such as the study of sedimentary archives it enables a direct coupling between eroding and deposition sites. However, meteoric 10Be can be mobilized within the soil. Therefore, spatial variations in meteoric 10Be inventories cannot directly be translated into spatial variations in erosion and sedimentation rates: a correct interpretation of measured 10Be inventories requires that both lateral and vertical movement of meteoric 10Be are accounted for. Here, we present a spatially explicit 2D model that allows to simulate the behaviour of meteoric 10Be in the soil system over timescales of up to 1 million year and use the model to investigate the impact of accelerated erosion on meteoric 10Be inventories. The model consists of two parts. A first component deals with advective and diffusive mobility within the soil profile, whereas a second component describes lateral soil (and meteoric 10Be) fluxes over the hillslope. Soil depth is calculated dynamically, accounting for soil production through weathering and lateral soil fluxes. Different types of erosion such as creep, water and tillage erosion are supported. Model runs show that natural soil fluxes can be well reconstructed based on meteoric 10Be inventories, and this for a wide range of geomorphological and pedological conditions. However, extracting signals of human impact and distinguishing them from natural soil fluxes is only feasible when the soil has a rather high retention capacity so that meteoric 10Be is retained in the top soil layer. Application of the Be2D model to an existing data set in the Appalachian Mountains [West et al.,2013] using realistic parameter values for the soil retention capacity as well as for vertical advection resulted in a good agreement between simulated and observed 10Be inventories. This confirms the robustness of the model. We

The Surface Age of Sputnik Planum, Pluto, Must Be Less than 10 Million Years.

PubMed

Trilling, David E

2016-01-01

Data from the New Horizons mission to Pluto show no craters on Sputnik Planum down to the detection limit (2 km for low resolution data, 625 m for high resolution data). The number of small Kuiper Belt Objects that should be impacting Pluto is known to some degree from various astronomical surveys. We combine these geological and telescopic observations to make an order of magnitude estimate that the surface age of Sputnik Planum must be less than 10 million years. This maximum surface age is surprisingly young and implies that this area of Pluto must be undergoing active resurfacing, presumably through some cryo-geophysical process. We discuss three possible resurfacing mechanisms and the implications of each one for Pluto's physical properties.

The Surface Age of Sputnik Planum, Pluto, Must Be Less than 10 Million Years

PubMed Central

Trilling, David E.

2016-01-01

Data from the New Horizons mission to Pluto show no craters on Sputnik Planum down to the detection limit (2 km for low resolution data, 625 m for high resolution data). The number of small Kuiper Belt Objects that should be impacting Pluto is known to some degree from various astronomical surveys. We combine these geological and telescopic observations to make an order of magnitude estimate that the surface age of Sputnik Planum must be less than 10 million years. This maximum surface age is surprisingly young and implies that this area of Pluto must be undergoing active resurfacing, presumably through some cryo-geophysical process. We discuss three possible resurfacing mechanisms and the implications of each one for Pluto’s physical properties. PMID:26790001

77 FR 11651 - Hybrid III 10-Year-Old Child Test Dummy

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-27

... tests. Some commenters (Dorel Juvenile Group (Dorel), Graco Children's Products (Graco)) expressed... event. Because it is made from one part instead of two, the HIII-10C shoulder was able to be designed... shoulder has had problems over the years. In early versions of the design (pre-NPRM), the shoulder had a...

Be2D: A model to understand the distribution of meteoric 10Be in soilscapes

NASA Astrophysics Data System (ADS)

Campforts, Benjamin; Vanacker, Veerle; Vanderborght, Jan; Govers, Gerard

2016-04-01

Cosmogenic nuclides have revolutionised our understanding of earth surface process rates. They have become one of the standard tools to quantify soil production by weathering, soil redistribution and erosion. Especially Beryllium-10 has gained much attention due to its long half-live and propensity to be relatively conservative in the landscape. The latter makes 10Be an excellent tool to assess denudation rates over the last 1000 to 100 × 103 years, bridging the anthropogenic and geological time scale. Nevertheless, the mobility of meteoric 10Be in soil systems makes translation of meteoric 10Be inventories into erosion and deposition rates difficult. Here we present a coupled soil hillslope model, Be2D, that is applied to synthetic and real topography to address the following three research questions. (i) What is the influence of vertical meteoric Be10 mobility, caused by chemical mobility, clay translocation and bioturbation, on its lateral redistribution over the soilscape, (ii) How does vertical mobility influence erosion rates and soil residence times inferred from meteoric 10Be inventories and (iii) To what extent can a tracer with a half-life of 1.36 Myr be used to distinguish between natural and human-disturbed soil redistribution rates? The model architecture of Be2D is designed to answer these research questions. Be2D is a dynamic model including physical processes such as soil formation, physical weathering, clay migration, bioturbation, creep, overland flow and tillage erosion. Pathways of meteoric 10Be mobility are simulated using a two step approach which is updated each timestep. First, advective and diffusive mobility of meteoric 10Be is simulated within the soil profile and second, lateral redistribution because of lateral soil fluxes is calculated. The performance and functionality of the model is demonstrated through a number of synthetic and real model runs using existing datasets of meteoric 10Be from case-studies in southeastern US. Brute

The production of coenzyme Q10 in microorganisms.

PubMed

Cluis, Corinne P; Pinel, Dominic; Martin, Vincent J

2012-01-01

Coenzyme Q10 has emerged as a valuable molecule for pharmaceutical and cosmetic applications. Therefore, research into producing and optimizing coenzyme Q10 via microbial fermentation is ongoing. There are two major paths being explored for maximizing production of this molecule to commercially advantageous levels. The first entails using microbes that naturally produce coenzyme Q10 as fermentation biocatalysts and optimizing the fermentation parameters in order to reach industrial levels of production. However, the natural coenzyme Q10-producing microbes tend to be intractable for industrial fermentation settings. The second path to coenzyme Q10 production being explored is to engineer Escherichia coli with the ability to biosynthesize this molecule in order to take advantage of its more favourable fermentation characteristics and the well-understood array of genetic tools available for this bacteria. Although many studies have attempted to over-produce coenzyme Q10 in E. coli through genetic engineering, production titres still remain below those of the natural coenzyme Q10-producing microorganisms. Current research is providing the knowledge needed to alleviate the bottlenecks involved in producing coenzyme Q10 from an E. coli strain platform and the fermentation parameters that could dramatically increase production titres from natural microbial producers. Synthesizing the lessons learned from both approaches may be the key towards a more cost-effective coenzyme Q10 industry.

Methods to Prove 20+ Year Life of CPV Products (in less than 20 Years)

NASA Astrophysics Data System (ADS)

Bowman, John; Spencer, Mark

2011-12-01

Due to the long term life expectations of photovoltaic products and the short duration of most introduced CPV technologies, it is critical for CPV companies to carefully construct field trials to prove product life. Because of the complicated geometric, thermal, and spectral characteristics of CPV systems, conducting very precise power output measurements reproducibly over many months is very difficult. Robust normalization methods specific to the exact optical system and PV cell type must be developed. Once the performance over a specific duration, e.g. one year, is established, then some justification is required to extrapolate to future performance. Comparisons to accelerated test results provide this justification. SolFocus has been conducting field trials of the SF-1100S CPV system for over two years. These field trials consist of controlled populations of SF-1100P modules, operating in grid-tied systems, which have been repeatedly measured at the individual module level over the duration of the trials. In this paper, field data will be presented along with normalization methodology and statistical methods for determining power degradation slope distributions for populations of individual modules. These results will be correlated with accelerated field tests which have been ongoing for 1.5 years and are estimated to be equivalent to 10 to 15 years of non-accelerated operation.

Surrogate mothers 10 years on: a longitudinal study of psychological well-being and relationships with the parents and child.

PubMed

Jadva, V; Imrie, S; Golombok, S

2015-02-01

How do the psychological health and experiences of surrogate mothers change from 1 year to 10 years following the birth of the surrogacy child? The psychological well-being of surrogate mothers did not change 10 years following the birth, with all remaining positive about the surrogacy arrangement and the majority continuing to report good mental health. Studies have found that surrogates may find the weeks following the birth difficult, but do not experience psychological problems 6 months or 1 year later. Research has also shown that surrogates can form close relationships with the intended parents during the pregnancy which may continue after the birth. This study used a prospective longitudinal design, in which 20 surrogates were seen at two time points: 1 year following the birth of the surrogacy child and 10 years later. The 20 surrogates (representing 59% of the original sample) participated in a semi-structured interview and completed self-report questionnaires. Eleven surrogates were gestational carriers and nine surrogates had used their own oocyte (genetic surrogacy). Four were previously known to the intended parents and 16 were previously not known. Ten years following the birth of the surrogacy child, surrogate mothers scored within the normal range for self-esteem and did not show signs of depression as measured by the Beck Depression Inventory. Marital quality remained positive over time. All surrogates reported that their expectations of their relationship with the intended parents had been either met or exceeded and most reported positive feelings towards the child. In terms of expectations for the future, most surrogates reported that they would like to maintain contact or would be available to the child if the child wished to contact them. None expressed regrets about their involvement in surrogacy. The sample size of this study was small and the women may not be representative of all surrogates. Therefore the extent to which these findings can

CELBAN™: A 10-Year Retrospective Catherine Lewis & Blanche Kingdon

ERIC Educational Resources Information Center

Lewis, Catherine; Kingdom, Blanche

2016-01-01

This article provides a 10-year review by the test developers of the Canadian English Language Benchmark Assessment for Nurses (CELBAN™). From 2004 to 2014, the development, implementation, national administration, and operations of CELBAN and CELBAN-related products and services were the responsibility of the test developers and team at the…

Cosmic ray production rates of Be-10 and Al-26 in quartz from glacially polished rocks

NASA Technical Reports Server (NTRS)

Nishiizumi, K.; Kohl, C. P.; Winterer, E. L.; Klein, J.; Middleton, R.

1989-01-01

The concentrations of Be-10 and Al-26 in quartz crystals extracted from glacially polished granitic surfaces from the Sierra Nevada range are studied. These surfaces are identified with the glacial advance during the Tioga period about 11,000 yr ago. The measurements yield the most accurate estimates to date for the absolute production rates of three nuclides in SiO2 due to cosmic ray nucleons and muons for geomagnetic latitudes 43.8-44.6 N and altitudes 2.1-3.6 km.

Testing the potential of 10Be in varved sediments from two lakes for solar activity reconstruction

NASA Astrophysics Data System (ADS)

Czymzik, Markus; Muscheler, Raimund; Brauer, Achim; Adolphi, Florian; Ott, Florian; Kienel, Ulrike; Dräger, Nadine; Slowinski, Michal; Aldahan, Ala; Possnert, Göran

2015-04-01

The potential of 10Be in annually laminated (varved) lake sediments for solar activity reconstruction is, to date, largely unexplored. It is hypothesized that 10Be contents in sediments from well-chosen lakes reflect the solar induced atmospheric production signal. The varved nature of these archives provides the chance to establish solar activity time-series with very high temporal precision. However, so far solar activity reconstruction from 10Be in varved lake sediments is hampered due to a lack of detailed knowledge of the process chain from production in the atmosphere to deposition on the lake floor. Calibrating 10Be time-series from varved lake sediments against complementary proxy records from the same sediment archive as well as instrumental meteorological and solar activity data will allow a process-based understanding of 10Be deposition in these lakes and a quantitative evaluation of their potential for solar activity reconstruction. 10Be concentration and flux time-series at annual resolution were constructed for the period 1983 to 2007 (approx. solar cycles 22 and 23) conducting accelerator mass spectrometry and varve chronology on varved sediments of Lakes Tiefer See and Czechowski, located on an east-west transect at a distance of about 450 km in the lowlands of northern-central Europe. 10Be concentrations vary between 0.9 and 1.8*108atoms/g, with a mean of 1.3*108atoms/g in Lake Tiefer See and between 0.6 and 1.6*108atoms/g, with a mean of 1*108atoms/g in Lake Czechowski. Calculated mean 10Be flux is 2.3*108atoms/cm2/year for Lake Tiefer See and 0.7*108atoms/cm2/year for Lake Czechowski. Calibrating the 10Be time-series against corresponding geochemical μ-XRF profiles, varve thickness and total organic carbon records as well as precipitation data from the nearby stations Schwerin for Lake Tiefer See and Koscierzyna for Lake Czechowski and a neutron monitor record of solar activity suggests (1) a complex interaction of varying processes influencing

30 CFR 14.10 - Post-approval product audit.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Post-approval product audit. 14.10 Section 14... General Provisions § 14.10 Post-approval product audit. (a) Approved conveyor belts will be subject to... applicant and other persons agreed upon by MSHA and the applicant may be present during audit tests and...

30 CFR 14.10 - Post-approval product audit.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Post-approval product audit. 14.10 Section 14... General Provisions § 14.10 Post-approval product audit. (a) Approved conveyor belts will be subject to... applicant and other persons agreed upon by MSHA and the applicant may be present during audit tests and...

30 CFR 14.10 - Post-approval product audit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Post-approval product audit. 14.10 Section 14... General Provisions § 14.10 Post-approval product audit. (a) Approved conveyor belts will be subject to... applicant and other persons agreed upon by MSHA and the applicant may be present during audit tests and...

46 CFR 159.007-11 - Production inspections and tests: Yearly report.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 6 2010-10-01 2010-10-01 false Production inspections and tests: Yearly report. 159.007-11 Section 159.007-11 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Production Inspection and Tests of Approved Equipment an...

46 CFR 159.007-11 - Production inspections and tests: Yearly report.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 6 2011-10-01 2011-10-01 false Production inspections and tests: Yearly report. 159.007-11 Section 159.007-11 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Production Inspection and Tests of Approved Equipment an...

7 CFR 927.10 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 927.10 Section 927.10 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 927.10 Production area. Production area means and includes the...

Sensitivity and response of beryllium-10 in marine sediments to rapid production changes (geomagnetic events): A box model study

NASA Astrophysics Data System (ADS)

Christl, Marcus

2007-09-01

The response and the sensitivity of the marine beryllium-10 flux to abrupt production changes (e.g., caused by a geomagnetic event) are investigated by using a simple box model. The effect of mixing processes in the water column on the 10Be flux is simulated, and the influence of bioturbation on the sedimentary record is studied. While the effect of the oceanic residence time is found to be small, bioturbation can drastically change the shape and the amplitude of the modeled 10Be peak. The simulations indicate that 10Be production peaks persisting for more than 1500 years are recorded well in deep-sea sediments if bioturbation-induced integration times are small (tbio ≤ 1000 years), while sediment cores with tbio ≥ 1000 years are found to be not well suited for stratigraphic purposes. The results further show that the sedimentary 10Be peak lags initial signal. This time lag is almost independent of the event duration (for tbio ≤ 1000 years), ranging between about 400 and 600 years. Therefore the model results support the idea that marine 10Be peaks corresponding to geomagnetic events can be used as a global time marker to match marine, terrestrial, and ice core chronologies on the millennial and (if the time lag of (500 ± 100) years is considered) the submillennial timescale.

The Top 10 Products

ERIC Educational Resources Information Center

American School & University, 2008

2008-01-01

In 2008, American School & University showcased some of the hottest products in the industry. This article presents the 10 most requested, as determined by readers. Products include fluorescent lighting, concrete floor maintenance and exterior sheathing.

Data Assembly and Processing for Operational Oceanography: 10 Years of Achievements

DTIC Science & Technology

2009-07-20

Processing for Operational Oceanography: 10 Years of Acheivements 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 0602435N 6... operational oceanography infrastructure. They provide data and products needed by modeling and data assimilation systems; they also provide products...directly useable for applications. The paper will discuss the role and functions of the data centers for operational oceanography and describe some of

10Be and relative paleointensity signals across the last geomagnetic reversal

NASA Astrophysics Data System (ADS)

Savranskaia, T.; Valet, J. P.; Bassinot, F. C.; Meynadier, L.; Simon, Q.; Bourles, D. L.; Thouveny, N.; Thevarasan, A.; Villedieu, A.; Choy, S.; Gacem, L.

2017-12-01

Two techniques can be used to determine the evolution of the geomagnetic field intensity in the past. The first one relies on records of relative paleointensity (RPI) in sediments. Although they remain relatively sparse detailed records of 10Be production (expressed in terms of 10Be/9Be) provide an alternative approach. However integration of 10Be within the sediment is not better understood than the magnetization process, and therefore paleofield studies should greatly benefit from the integration of both datasets. In order to achieve this goal, it is crucial to compare and analyze the signals over a common time period. We selected five sedimentary cores from the Indian, Pacific and Atlantic Oceans and focused on the last reversal which is characterized by the largest intensity changes. Since 10Be is homogenized in the atmosphere, the same amount of 10Be should be recorded everywhere. We found different amounts of 10Be at each site during the last reversal which appear roughly correlated with accumulation rate. In contrast the 10Be amplitude is similar at all locations while higher amplitude signals are expected for low deposition rates. Taking advantage of the distribution of tektites layers, the beryllium signals have been deconvolved, but this procedure did not strikingly change the results. Despite atmospheric mixing we wonder whether 10Be production was slightly different at each location in presence of a multipolar transitional field. The comparison between the 10Be and RPI signals reveals large similarities but also puzzling differences. In particular, the relationship between the two signals is not the same during periods of stable polarity as during the transitional interval. A precursor with low intensity is present in several RPI records but not clearly marked on the beryllium records. We also addressed the question of a possible offset between the two signals that would be indicative of a delayed magnetization acquisition. After correlating and

Validation of 10-year SAO OMI Ozone Profile (PROFOZ) product using ozonesonde observations

NASA Astrophysics Data System (ADS)

Huang, Guanyu; Liu, Xiong; Chance, Kelly; Yang, Kai; Bhartia, Pawan K.; Cai, Zhaonan; Allaart, Marc; Ancellet, Gérard; Calpini, Bertrand; Coetzee, Gerrie J. R.; Cuevas-Agulló, Emilio; Cupeiro, Manuel; De Backer, Hugo; Dubey, Manvendra K.; Fuelberg, Henry E.; Fujiwara, Masatomo; Godin-Beekmann, Sophie; Hall, Tristan J.; Johnson, Bryan; Joseph, Everette; Kivi, Rigel; Kois, Bogumil; Komala, Ninong; König-Langlo, Gert; Laneve, Giovanni; Leblanc, Thierry; Marchand, Marion; Minschwaner, Kenneth R.; Morris, Gary; Newchurch, Michael J.; Ogino, Shin-Ya; Ohkawara, Nozomu; Piters, Ankie J. M.; Posny, Françoise; Querel, Richard; Scheele, Rinus; Schmidlin, Frank J.; Schnell, Russell C.; Schrems, Otto; Selkirk, Henry; Shiotani, Masato; Skrivánková, Pavla; Stübi, René; Taha, Ghassan; Tarasick, David W.; Thompson, Anne M.; Thouret, Valérie; Tully, Matthew B.; Van Malderen, Roeland; Vömel, Holger; von der Gathen, Peter; Witte, Jacquelyn C.; Yela, Margarita

2017-07-01

We validate the Ozone Monitoring Instrument (OMI) Ozone Profile (PROFOZ) product from October 2004 through December 2014 retrieved by the Smithsonian Astrophysical Observatory (SAO) algorithm against ozonesonde observations. We also evaluate the effects of OMI row anomaly (RA) on the retrieval by dividing the dataset into before and after the occurrence of serious OMI RA, i.e., pre-RA (2004-2008) and post-RA (2009-2014). The retrieval shows good agreement with ozonesondes in the tropics and midlatitudes and for pressure < ˜ 50 hPa in the high latitudes. It demonstrates clear improvement over the a priori down to the lower troposphere in the tropics and down to an average of ˜ 550 (300) hPa at middle (high) latitudes. In the tropics and midlatitudes, the profile mean biases (MBs) are less than 6 %, and the standard deviations (SDs) range from 5 to 10 % for pressure < ˜ 50 hPa to less than 18 % (27 %) in the tropics (midlatitudes) for pressure > ˜ 50 hPa after applying OMI averaging kernels to ozonesonde data. The MBs of the stratospheric ozone column (SOC, the ozone column from the tropopause pressure to the ozonesonde burst pressure) are within 2 % with SDs of < 5 % and the MBs of the tropospheric ozone column (TOC) are within 6 % with SDs of 15 %. In the high latitudes, the profile MBs are within 10 % with SDs of 5-15 % for pressure < ˜ 50 hPa but increase to 30 % with SDs as great as 40 % for pressure > ˜ 50 hPa. The SOC MBs increase up to 3 % with SDs as great as 6 % and the TOC SDs increase up to 30 %. The comparison generally degrades at larger solar zenith angles (SZA) due to weaker signals and additional sources of error, leading to worse performance at high latitudes and during the midlatitude winter. Agreement also degrades with increasing cloudiness for pressure > ˜ 100 hPa and varies with cross-track position, especially with large MBs and SDs at extreme off-nadir positions. In the tropics and midlatitudes, the post-RA comparison is considerably

Counting the cost of negligence in neurosurgery: Lessons to be learned from 10 years of claims in the NHS.

PubMed

Hamdan, Alhafidz; Strachan, Roger D; Nath, Fredrick; Coulter, Ian C

2015-04-01

Despite substantial progress in modernising neurosurgery, the specialty still tops the list of medico-legal claims. Understanding the factors associated with negligence claims is vital if we are to identify areas of underperformance and subsequently improve patient safety. Here we provide data on trends in neurosurgical negligence claims over a 10-year period in England. We used data provided by the National Health Service Litigation Authority to analyse negligence claims related to neurosurgery from the financial years 2002/2003 to 2011/2012. Using the abstracts provided, we extracted information pertaining to the underlying pathology, injury severity, nature of misadventure and claim value. Over the 10-year period, the annual number of claims increased significantly. In total, there were 794 negligence claims (range 50-117/year); of the 613 closed cases, 405 (66.1%) were successful. The total cost related to claims during the 10 years was £65.7 million, with a mean claim per successful case of £0.16 million (total damages, defence and claimant costs of £45.1, £6.36 and £14.3 million, respectively). Claims related to emergency cases were more costly compared to those of elective cases (£209,327 vs. £112,627; P=0.002). Spinal cases represented the most frequently litigated procedures (350; 44.1% of total), inadequate surgical performance the most common misadventure (231; 29.1%) and fatality the commonest injury implicated in claims (102; 12.8%). Negligence claims related to wrong-site surgery and cauda equina syndrome were frequently successful (26/26; 100% and 14/16; 87.5% of closed cases, respectively). In England, the number of neurosurgical negligence claims is increasing, the financial cost substantial, and the burden significant. Lessons to be learned from the study are of paramount importance to reduce future cases of negligence and improve patient care.

10 Years of Media Literacy Education in K-12 Schools

ERIC Educational Resources Information Center

Daunic, Rhys

2011-01-01

When the author started working with teachers and students on classroom multimedia productions a little over 10 years ago, he had not yet encountered the term "media literacy", nor did he realize he had joined a long standing international movement of media literacy educators. Serendipitous exposure to "old-media" texts by Neil Postman and Noam…

Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized double-blind placebo-controlled trial in elderly.

PubMed

Alehagen, Urban; Aaseth, Jan; Alexander, Jan; Johansson, Peter

2018-01-01

Selenium and coenzyme Q10 are both necessary for optimal cell function in the body. The intake of selenium is low in Europe, and the endogenous production of coenzyme Q10 decreases as age increases. Therefore, an intervention trial using selenium and coenzyme Q10 for four years as a dietary supplement was performed. The main publication reported reduced cardiovascular mortality as a result of the intervention. In the present sub-study the objective was to determine whether reduced cardiovascular (CV) mortality persisted after 12 years, in the supplemented population or in subgroups with diabetes, hypertension, ischemic heart disease or reduced functional capacity due to impaired cardiac function. From a rural municipality in Sweden, four hundred forty-three healthy elderly individuals were included. All cardiovascular mortality was registered, and no participant was lost to the follow-up. Based on death certificates and autopsy results, mortality was registered. After 12 years a significantly reduced CV mortality could be seen in those supplemented with selenium and coenzyme Q10, with a CV mortality of 28.1% in the active treatment group, and 38.7% in the placebo group. A multivariate Cox regression analysis demonstrated a reduced CV mortality risk in the active treatment group (HR: 0.59; 95%CI 0.42-0.81; P = 0.001). In those with ischemic heart disease, diabetes, hypertension and impaired functional capacity we demonstrated a significantly reduced CV mortality risk. This is a 12-year follow-up of a group of healthy elderly participants that were supplemented with selenium and coenzyme Q10 for four years. Even after twelve years we observed a significantly reduced risk for CV mortality in this group, as well as in subgroups of patients with diabetes, hypertension, ischemic heart disease or impaired functional capacity. The results thus validate the results obtained in the 10-year evaluation. The protective action was not confined to the intervention period, but

Can Climate Information be relevant to decision making for Agriculture on the 1-10 year timescale? Case studies from southern Africa

NASA Astrophysics Data System (ADS)

Fujisawa, Mariko

2016-04-01

Climate forecasts have been developed to assist decision making in sectors averse to, and affected by, climate risks, and agriculture is one of those. In agriculture and food security, climate information is now used on a range of timescales, from days (weather), months (seasonal outlooks) to decades (climate change scenarios). Former researchers have shown that when seasonal climate forecast information was provided to farmers prior to decision making, farmers adapted by changing their choice of planting seeds and timing or area planted. However, it is not always clear that the end-users' needs for climate information are met and there might be a large gap between information supplied and needed. It has been pointed out that even when forecasts were available, they were often not utilized by farmers and extension services because of lack of trust in the forecast or the forecasts did not reach the targeted farmers. Many studies have focused on the use of either seasonal forecasts or longer term climate change prediction, but little research has been done on the medium term, that is, 1 to 10 year future climate information. The agriculture and food system sector is one potential user of medium term information, as land use policy and cropping systems selection may fall into this time scale and may affect farmers' decision making process. Assuming that reliable information is provided and it is utilized by farmers for decision making, it might contribute to resilient farming and indeed to longer term food security. To this end, we try to determine the effect of medium term climate information on farmers' strategic decision making process. We explored the end-users' needs for climate information and especially the possible role of medium term information in agricultural system, by conducting interview surveys with farmers and agricultural experts. In this study, the cases of apple production in South Africa, maize production in Malawi and rice production in Tanzania

10 Year Publication Trends in Dermatology in Mainland China

PubMed Central

Xin, Shujun; Mauro, Jacqueline A; Mauro, Theodora M; Elias, Peter M; Man, Mao-Qiang

2013-01-01

Background China has been experiencing huge changes in all aspects including dermatologic research since its reform in 1978. However, how the economic and intellectual development has influenced the publication trends in the field of dermatology, which could mirror the scientific development in other medical disciplines, is unknown. In the present study, we analyzed the publication trends from departments of dermatology in mainland China from 2002 to 2011. Materials and Methods All publication data were obtained from www.pubmed.com. Only papers published from dermatology departments of mainland China were used for analysis. Results The number of publications increased 10-fold over this 10 year period. A total 1,231 of articles were published in English in 251 journals between 2002 and 2011. A total of 129 journals published only one paper from dermatology departments of mainland China. Over 60% of articles were original research and 21.7% were case reports. Among these 251 journals, foremost was the Journal of Clinical Experimental Dermatology, which published 5.9% of all papers from mainland China. 2.7% papers were published in the Journal of Investigative Dermatology. The number of publications positively correlated with the changes in gross domestic product per capita during the study period. Conclusions These results suggest that the number of publications in the dermatology field has increased markedly in mainland China over the last 10 years. This dramatic increase in publications could be, at least partially, attributed to the significant improvement in economic conditions in mainland China. PMID:23968296

Six-year beechnut production in New Hampshire. Forest Service research paper (Final)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leak, W.B.; Graber, R.E.

1993-08-01

The Beechnut production and losses were studied over a 6-year period in 41 northern hardwood stands ranging in age from 10 to 140 years in the White Mountains of New Hampshire. Beechnut production increased consistently with stand age or diameter at base height of dominant trees and percentage of basal area composed of beech. Losses to insects, rodents, and birds before the seed reached the ground ranged from 24 to 100 percent; insects caused the greatest losses. Good seed years occurred about every third year.

Breeding objectives for sheep should be customised depending on variation in pasture growth across years.

PubMed

Rose, G; Mulder, H A; Thompson, A N; van der Werf, J H J; van Arendonk, J A M

2015-08-01

Breeding programmes for livestock require economic weights for traits that reflect the most profitable animal in a given production system, which affect the response in each trait after selection. The profitability of sheep production systems is affected by changes in pasture growth as well as grain, meat and wool prices between seasons and across years. Annual pasture growth varies between regions within Australia's Mediterranean climate zone from low growth with long periods of drought to high growth with shorter periods of drought. Therefore, the objective of this study was to assess whether breeding objectives need to be adapted for regions, depending on how reliable the pasture growth is across years. We modelled farms with Merino sheep bred for wool and meat in 10 regions in Western Australia. Across these 10 regions, mean annual pasture growth decreased, and the CV of annual pasture growth increased as pasture growth for regions became less reliable. We calculated economic values for nine traits, optimising management across 11 years, including variation for pasture growth and wool, meat and grain prices between and within years from 2002 to 2012. These economic values were used to calculate responses to selection for each trait for the 10 regions. We identified two potential breeding objectives, one for regions with low or high reliability and the other for regions with medium reliability of pasture growth. Breeding objectives for high or low pasture growth reliability had more emphasis on live weight traits and number of lambs weaned. Breeding objectives for medium reliability of pasture growth had more emphasis on decreasing fibre diameter. Relative economic weights for fleece weight did not change across the regions. Regions with low or high pasture reliability had similar breeding objectives and response to selection, because the relationship between the economic values and CV of pasture growth were not linear for live weight traits and the number of

Well-being improvement in a midsize employer: changes in well-being, productivity, health risk, and perceived employer support after implementation of a well-being improvement strategy.

PubMed

Hamar, Brent; Coberley, Carter; Pope, James E; Rula, Elizabeth Y

2015-04-01

To evaluate employee well-being change and associated change in productivity, health risk including biometrics, and workplace support over 2 years after implementation of a well-being improvement strategy. This was an employer case study evaluation of well-being, productivity (presenteeism, absenteeism, and job performance), health risk, and employer support across three employee assessment spanning 2 years. Employee well-being was compared with an independent sample of workers in the community. Well-being and job performance increased and presenteeism and health risk decreased significantly over the 2 years. Employee well-being started lower and increased to exceed community worker averages, approaching significance. Well-being improvement was associated with higher productivity across all measures. Increases in employer support for well-being were associated with improved well-being and productivity. This employer's well-being strategy, including a culture supporting well-being, was associated with improved health and productivity.

Species Diversity Effects on Productivity, Persistence and Quality of Multispecies Swards in a Four-Year Experiment.

PubMed

Jing, Jingying; Søegaard, Karen; Cong, Wen-Feng; Eriksen, Jørgen

2017-01-01

Plant species diversity may benefit natural grassland productivity, but its effect in managed grassland systems is not well understood. A four-year multispecies grassland experiment was conducted to investigate the effect of species diversity-legumes and non-leguminous forbs-on productivity, persistence and sward quality under cutting or grazing regimes and with or without slurry application. Three mixtures were established- 3-mix: grass, red and white clover, 10-mix: 3-mix plus birdsfoot trefoil and six non-leguminous forbs, and 12-mix: 10-mix plus lucerne and festulolium. Species diversity increased sward production and yield persistence under cutting regime. The 12-mix had the highest yield from the second year onwards and no statistically significant yield reduction over four years, while annual yields in the 3-mix and 10-mix decreased significantly with increasing grassland age. The higher yield in the 12-mix was mainly due to the inclusion of high-yielding lucerne. The 10-mix and 12-mix had lower proportions of unsown species than the 3-mix, the difference being dependent on grassland age. Generally, the 3-mix had higher concentrations of in-vitro organic matter digestibility (IVOMD), neutral detergent fiber (NDF) and crude protein (CP), and a lower concentration of ash than the 10-mix and 12-mix. Slurry application increased annual yield production by 10% and changed the botanical composition, increasing the proportion of grass and decreasing the proportion of legumes. Compared to cutting, grazing increased forage production by 9% per cut on average and lowered legume and forb proportions in the mixtures, but yields did not differ among the three mixtures. Overall, our results suggest that species diversity increases sward productivity and persistence only under an ungrazed cutting regime. We conclude that increasing species diversity by selecting appropriate species with compatible management is key to achieving both high yields and high persistence in

Reactive and dissolved meteoric 10Be/9Be ratios in the Amazon basin

NASA Astrophysics Data System (ADS)

Wittmann, Hella; Dannhaus, Nadine; von Blanckenburg, Friedhelm; Bouchez, Julien; Suessenberger, Annette; Guyot, Jean-Loup; Maurice, Laurence; Filizola, Naziano; Gaillardet, Jerome; Christl, Marcus

2014-05-01

Recently, the ratio of the meteoric cosmogenic nuclide 10Be to stable 9Be has been established as a weathering and erosion proxy where meteoric 10Be/9Be ratios in reactive phases of secondary weathering products leached from detrital Amazonian river sediment were measured[1]. For this dataset, we derived a new 10Be-based mass balance, which compares the fluxes exported during erosion and weathering, Fout, calculated by the sum of [10Be]reac multiplied by gauging-derived sediment discharge and [10Be]dissmultiplied by water discharge, to the meteoric depositional flux Fin. This assessment allows evaluating the weathering state of the Amazon basin. Further, in order to assess equilibration of reactive phases in the water column, we measured (10Be/9Be)reac ratios leached from suspended sediments for two depth profiles of the Amazon (55m depth) and Madeira (12m depth) Rivers, their corresponding surface dissolved 10Be/9Be ratios, as well as dissolved ratios of smaller Amazon tributaries (Beni, Madre de Dios) to compare with published reactive ratios[1]. In these rivers, modest pH and salinity fluctuations help to constrain a 'simple' system that might however still be affected by seasonally changing isotopic compositions between water and suspended sediment[2] and seasonal fluctuations of TSS and TDS[3]. The 10Be-based mass balance shows that in Andean source areas Fout/Fin ≡1, indicating a balance between ingoing and exported flux, whereas in the Shield headwaters, Fout/Fin=0.3, indicating a combination of decay of 10Be during storage and little export of 10Be associated with particulate and dissolved loads. In central Amazonia, the export of 10Be decreases slightly relative to its atmospheric flux as evidenced by Fout/Fin=0.8 for the Amazon and Madeira Rivers. This value is interpreted as being close to steady state, but its modification could be due to additions of Shield-derived sediment to sediment carried in the main river[4]. Regarding the depth profiles, our

A deterministic, dynamic systems model of cow-calf production: The effects of the duration of postpartum anestrus on production parameters over a 10-year horizon.

PubMed

Shane, D D; Larson, R L; Sanderson, M W; Miesner, M; White, B J

2017-04-01

The duration of postpartum anestrus (dPPA) is important to consider for reproductive performance and efficiency in cow-calf operations. We developed a deterministic, dynamic systems model of cow-calf production over a 10-yr horizon to model the effects that dPPA had on measures of herd productivity, including the percentage of cows cycling before the end of the first 21 d of the breeding season (%C21), the percentage of cows pregnant at pregnancy diagnosis (%PPD), the distribution of pregnancy by 21-d breeding intervals, the kilograms of calf weaned (KW), the kilograms of calf weaned per cow exposed (KPC), and the replacement percentage. A 1,000-animal herd was modeled, with the beginning and ending dates for a 63-d natural service breeding season being the same for eligible replacement heifers (nulliparous cows) and cows (primiparous and multiparous cows). Herds were simulated to have a multiparous cow dPPA of 50, 60, 70, or 80 d, with the dPPA for primiparous cows being set to 50, 60, 70, 80, 90, 100, or 110 d. Only combinations where the primiparous dPPA was greater than or equal to the multiparous dPPA were included, resulting in 22 model herds being simulated in the analysis. All other model parameters were held constant between simulations. In model season 10, the %C21 was 96.2% when the multiparous cow and primiparous cow dPPA was 50 d and was 48.3% when the multiparous cow and primiparous cow dPPA was 80 d. The %PPD in model season 10 for these same herds was 95.1% and 86.0%, respectively. The percentage of the herd becoming pregnant in the first 21 d of the breeding season also differed between these herds (61.8% and 31.3%, respectively). The 10-yr total KW was more than 275,000 kg greater for the herd with a 50-d multiparous cow and primiparous cow dPPA when compared with the herd with the 80-d multiparous and primiparous cow dPPA and had a model season 10 KPC of 180.8 kg compared with 151.4 kg for the longer dPPA. The model results show that both the

Should Anthroposophic Medicinal Products Be Regulated in Europe?

PubMed

Michaux, Geneviève

2017-03-01

European Commission’s reports suggest that the European Union should address the status of anthroposophic products, i.e. products that are developed, manufactured and prescribed in accordance with the holistic approach on which anthroposophic medicine is based. Anthroposophic products cannot be placed as such on the European market because they cannot meet the marketing authorisation or even registration requirements set out by European or national pharmaceutical law. Yet, the 95-year European tradition and good safety profile of anthroposophic products justify giving them an easier access to market. Such access can result from specific rules on anthroposophic products, but can be more efficiently achieved by encouraging the Member States to better apply the existing rules on marketing authorisation procedures or on registration of homeopathic and traditional herbal medicinal products, or by including anthroposophic substances, manufacturing methods or uses in monographs.

7 CFR 52.10 - When application may be rejected.

Code of Federal Regulations, 2010 CFR

2010-01-01

... MARKETING ACT OF 1946 PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS THEREOF, AND CERTAIN OTHER PROCESSED FOOD PRODUCTS 1 Regulations Governing Inspection and Certification Inspection Service § 52.10 When...

Persistent psychological well-being predicts improved self-rated health over 9–10 years: Longitudinal evidence from MIDUS

PubMed Central

Radler, Barry T; Friedman, Elliot M

2015-01-01

Psychological well-being has been linked with better health, but mostly with cross-sectional evidence. Using MIDUS, a national sample of US adults (N = 4963), longitudinal profiles of well-being were used to predict cross-time change in self-reported health over 9–10 years. Well-being was largely stable, although adults differed in whether they had persistently high versus persistently low or moderate levels of well-being. After adjusting for sociodemographic factors, those with persistently high well-being reported better health (subjective health, chronic conditions, symptoms, and functional impairment) across time compared to those with persistently low well-being. Furthermore, persistently high well-being was protective of improved health especially among the educationally disadvantaged. The findings underscore the importance of intervention and educational programs designed to promote well-being for greater segments of society. PMID:26617988

Outdoor Cultivation of Marine Diatoms for Year-Round Production of Biofuels.

PubMed

Matsumoto, Mitsufumi; Nojima, Daisuke; Nonoyama, Tomomi; Ikeda, Kiichi; Maeda, Yoshiaki; Yoshino, Tomoko; Tanaka, Tsuyoshi

2017-03-25

Biofuel production using microalgae is believed to have the advantage of continuous year-round production over crop plants, which have strong seasonality. However, actual year-round production of microalgal lipids using outdoor mass cultivation has rarely been demonstrated. In our previous study, it was demonstrated that the oleaginous diatom, Fistulifera solaris , was culturable in outdoor bioreactors from spring to autumn, whereas biomass and lipid production in winter failed because F. solaris did not grow below 15 °C. Therefore, another candidate strain that is culturable in winter is required. In this study, a cold-tolerant diatom, Mayamaea sp. JPCC CTDA0820, was selected as a promising candidate for biofuel production in winter. Laboratory-scale characterization revealed that this diatom was culturable at temperatures as low as 10 °C. Subsequently, F. solaris (April-October) and Mayamaea sp. JPCC CTDA0820 (November-March) were cultured in outdoor open-pond bioreactors, wherein year-round production of diatom lipids was successfully demonstrated. The maximal values of areal productivities of biomass and lipids reached to 9.79 and 1.80 g/(m² day) for F. solaris , and 8.62 and 0.92 g/(m² day) for Mayamaea sp. JPCC CTDA0820, respectively. With the combined use of these two diatom species, stable year-round production of microalgal lipids became possible.

1 CFR 10.13 - Coverage of prior years.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 1 General Provisions 1 2011-01-01 2011-01-01 false Coverage of prior years. 10.13 Section 10.13... REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.13 Coverage of prior years. The Administrative Committee may authorize the publication of volumes of papers of the Presidents covering specified years...

1 CFR 10.13 - Coverage of prior years.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Coverage of prior years. 10.13 Section 10.13... REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.13 Coverage of prior years. The Administrative Committee may authorize the publication of volumes of papers of the Presidents covering specified years...

10 CFR 430.65 - Exported products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Exported products. 430.65 Section 430.65 Energy DEPARTMENT... Enforcement § 430.65 Exported products. Pursuant to section 330 of the Act, this part shall not apply to any covered product if (a) such covered product is manufactured, sold, or held for sale for export from the...

40 CFR 247.10 - Paper and paper products.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Paper and paper products. 247.10... COMPREHENSIVE PROCUREMENT GUIDELINE FOR PRODUCTS CONTAINING RECOVERED MATERIALS Item Designations § 247.10 Paper and paper products. Paper and paper products, excluding building and construction paper grades. ...

40 CFR 247.10 - Paper and paper products.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Paper and paper products. 247.10... COMPREHENSIVE PROCUREMENT GUIDELINE FOR PRODUCTS CONTAINING RECOVERED MATERIALS Item Designations § 247.10 Paper and paper products. Paper and paper products, excluding building and construction paper grades. ...

Maternal Prenatal Nutrition and Birth Outcomes on Malnutrition among 7- to 10-Year-Old Children: A 10-Year Follow-Up.

PubMed

Zhou, Jing; Zeng, Lingxia; Dang, Shaonong; Pei, Leilei; Gao, Wenlong; Li, Chao; Yan, Hong

2016-11-01

To identify postnatal predictors of malnutrition among 7- to 10-year-old children and to assess the long-term effects of antenatal micronutrient supplementation on malnutrition. A follow-up study was conducted to assess the nutritional status of 7- to 10-year-olds (1747 children) whose mothers participated in a cluster-randomized double-blind controlled trial from 2002 to 2006. The rate of malnourished 7- to 10-year-olds was 11.1%. A mixed-effects logistic regression model adjusted for the cluster-sampling design indicated that mothers with low prepregnant midupper arm circumference had boys with an increased risk of thinness (aOR  2.05, 95% CI  1.11, 3.79) and girls who were more likely to be underweight (aOR 2.01, 95% CI 1.05, 3.85). Antenatal micronutrient supplementation was not significantly associated with malnutrition. Low birth weight was significantly associated with increased odds of malnutrition among boys (aOR 4.34, 95% CI 1.82, 10.39) and girls (aOR  7.50, 95% CI 3.48, 16.13). Being small for gestational age significantly increased the odds of malnutrition among boys (aOR 1.75, 95% CI 1.01, 3.04) and girls (aOR 4.20, 95% CI  2.39, 7.39). In addition, household wealth, parental height, being picky eater, and illness frequency also predicted malnutrition. Both maternal prenatal nutrition and adverse birth outcomes are strong predictors of malnutrition among early school-aged children. Currently, available evidence is insufficient to support long-term effects of antenatal micronutrient supplementation on children's nutrition. www.isrctn.com: ISRCTN08850194. Copyright © 2016 Elsevier Inc. All rights reserved.

31 CFR 360.10 - Amounts which may be purchased.

Code of Federal Regulations, 2013 CFR

2013-07-01

... STATES SAVINGS BONDS, SERIES I Limitations on Annual Purchases § 360.10 Amounts which may be purchased. The amount of savings bonds of Series I which may be purchased and held, in the name of any one person....13, at any time during the calendar year in which the bonds are issued. [63 FR 38049, July 14, 1998...

31 CFR 360.10 - Amounts which may be purchased.

Code of Federal Regulations, 2010 CFR

2010-07-01

... UNITED STATES SAVINGS BONDS, SERIES I Limitations on Annual Purchases § 360.10 Amounts which may be purchased. The amount of savings bonds of Series I which may be purchased and held, in the name of any one....13, at any time during the calendar year in which the bonds are issued. [63 FR 38049, July 14, 1998...

31 CFR 360.10 - Amounts which may be purchased.

Code of Federal Regulations, 2014 CFR

2014-07-01

... UNITED STATES SAVINGS BONDS, SERIES I Limitations on Annual Purchases § 360.10 Amounts which may be purchased. The amount of savings bonds of Series I which may be purchased and held, in the name of any one....13, at any time during the calendar year in which the bonds are issued. [63 FR 38049, July 14, 1998...

The Cryptophlebia Leucotreta Granulovirus—10 Years of Commercial Field Use

PubMed Central

Moore, Sean D.; Kirkman, Wayne; Richards, Garth I.; Stephen, Peter R.

2015-01-01

In the last 15 years, extensive work on the Cryptophlebia leucotreta granulovirus (CrleGV) has been conducted in South Africa, initially in the laboratory, but subsequently also in the field. This culminated in the registration of the first CrleGV-based biopesticide in 2004 (hence, the 10 years of commercial use in the field) and the second one three years later. Since 2000, more than 50 field trials have been conducted with CrleGV against the false codling moth, Thaumatotibia leucotreta, on citrus in South Africa. In a representative sample of 13 field trials reported over this period, efficacy (measured by reduction in larval infestation of fruit) ranged between 30% and 92%. Efficacy was shown to persist at a level of 70% for up to 17 weeks after application of CrleGV. This only occurred where the virus was applied in blocks rather than to single trees. The addition of molasses substantially and sometimes significantly enhanced efficacy. It was also established that CrleGV should not be applied at less than ~2 × 1013 OBs per ha in order to avoid compromised efficacy. As CrleGV-based products were shown to be at least as effective as chemical alternatives, persistent and compatible with natural enemies, their use is recommended within an integrated program for control of T. leucotreta on citrus and other crops. PMID:25809025

How do retirement dynamics influence mental well-being in later life? A 10-year panel study.

PubMed

Dingemans, Ellen; Henkens, Kène

2015-01-01

Empirical studies have consistently shown the negative impact of involuntary retirement on mental well-being. However, few studies have thus far investigated the degree to which post-retirement work affects late-life outcomes. The present study improves our understanding of the impact of retirement on the self-efficacy and life satisfaction among older adults by focusing on the combined impact of retirement voluntariness and participation in post-retirement work. By using panel data on retirement behavior in the Netherlands, we estimate fixed effects and multilevel models to explain (intra-)individual changes in self-efficacy and life satisfaction over a 10-year period in which most participants made the transition to retirement. The results indicate that involuntary retirement is associated with decreases in both self-efficacy and life satisfaction in later life. Whereas involuntary retirees who participate in bridge jobs show no changes in life satisfaction, those involuntary retirees without bridge jobs experience a decline in life satisfaction. In addition, we found enhanced levels of life satisfaction for voluntary retirees in bridge employment. The association with self-efficacy was less pronounced. These results suggest that the characteristics of the retirement process influence changes in mental well-being in later life. Specifically, bridge employment alleviates the negative consequences of involuntary retirement and even seems to enhance post-retirement well-being for voluntary retirees.

10 CFR 430.64 - Imported products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Imported products. 430.64 Section 430.64 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY CONSERVATION PROGRAM FOR CONSUMER PRODUCTS Certification and Enforcement § 430.64 Imported products. (a) Pursuant to section 331 of the Act, any person importing any...

7 CFR 1212.10 - Honey products.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Honey products. 1212.10 Section 1212.10 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HONEY PACKERS AND IMPORTERS RESEARCH, PROMOTION, CONSUMER EDUCATION AND INDUSTRY INFORMATION ORDER Honey Packers and Importers Research, Promotion...

Measurements of production cross sections of 10Be and 26Al by 120 GeV and 392 MeV proton bombardment of 89Y, 159Tb, and natCu targets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sekimoto, S.; Okumura, S.; Yashima, H.

2015-08-12

The production cross sections of 10Be and 26Al were measured by accelerator mass spectrometry using 89Y, 159Tb, and natCu targets bombarded by protons with energies E p of 120 GeV and 392 MeV. The production cross sections obtained for 10Be and 26Al were compared with those previously reported using E p = 50 MeV–24 GeV and various targets. It was found that the production cross sections of 10Be monotonically increased with increasing target mass number when the proton energy was greater than a few GeV. On the other hand, it was also found that the production cross sections of 10Bemore » decreased as the target mass number increased from that of carbon to those near the mass numbers of nickel and zinc when the proton energy was below approximately 1 GeV. They also increased as the target mass number increased from near those of nickel and zinc to that of bismuth, in the same proton energy range. Similar results were observed in the production cross sections of 26Al, though the absolute values were quite different between 10Be and 26Al. As a result, the difference between these production cross sections may depend on the impact parameter (nuclear radius) and/or the target nucleus stiffness.« less

Aqua's First 10 Years: An Overview

NASA Technical Reports Server (NTRS)

Parkinson, Claire L.

2012-01-01

NASA's Aqua spacecraft was launched at 2:55 a.m. on May 4, 2002, from Vandenberg Air Force Base in California, into a near-polar, sun-synchronous orbit at an altitude of 705 km. Aqua carries six Earth-observing instruments to collect data on water in all its forms (liquid, vapor, and solid) and on a wide variety of additional Earth system variables (Parkinson 2003). The design lifetime for Aqua's prime mission was 6 years, and Aqua is now well into its extended mission, approaching 10 years of successful operations. The Aqua data have been used for hundreds of scientific studies and continue to be used for scientific discovery and numerous practical applications.

Greenhouse gas flux and crop productivity after 10 years of reduced and no tillage in a wheat-maize cropping system.

PubMed

Tian, Shenzhong; Wang, Yu; Ning, Tangyuan; Zhao, Hongxiang; Wang, Bingwen; Li, Na; Li, Zengjia; Chi, Shuyun

2013-01-01

Appropriate tillage plays an important role in mitigating the emissions of greenhouse gases (GHG) in regions with higher crop yields, but the emission situations of some reduced tillage systems such as subsoiling, harrow tillage and rotary tillage are not comprehensively studied. The objective of this study was to evaluate the emission characteristics of GHG (CH4 and N2O) under four reduced tillage systems from October 2007 to August 2009 based on a 10-yr tillage experiment in the North China Plain, which included no-tillage (NT) and three reduced tillage systems of subsoil tillage (ST), harrow tillage (HT) and rotary tillage (RT), with the conventional tillage (CT) as the control. The soil under the five tillage systems was an absorption sink for CH4 and an emission source for N2O. The soil temperature positive impacted on the CH4 absorption by the soils of different tillage systems, while a significant negative correlation was observed between the absorption and soil moisture. The main driving factor for increased N2O emission was not the soil temperature but the soil moisture and the content of nitrate. In the two rotation cycle of wheat-maize system (10/2007-10/2008 and 10/2008-10/2009), averaged cumulative uptake fluxes of CH4 under CT, ST, HT, RT and NT systems were approximately 1.67, 1.72, 1.63, 1.77 and 1.17 t ha(-1) year(-1), respectively, and meanwhile, approximately 4.43, 4.38, 4.47, 4.30 and 4.61 t ha(-1) year(-1) of N2O were emitted from soil of these systems, respectively. Moreover, they also gained 33.73, 34.63, 32.62, 34.56 and 27.54 t ha(-1) yields during two crop-rotation periods, respectively. Based on these comparisons, the rotary tillage and subsoiling mitigated the emissions of CH4 and N2O as well as improving crop productivity of a wheat-maize cropping system.

Be-10 in terrestrial bauxite and industrial aluminum: An LDEF fallout

NASA Technical Reports Server (NTRS)

Gregory, J. C.; Albrecht, A.; Herzog, G.; Klein, J.; Middleton, R.; Harmon, B. A.; Parnell, T. A.

1995-01-01

Work has continued on the search for Be-10 on metals other than aluminum flown on LDEF. Much time-consuming extractive chemistry has been performed at Rutgers University on turnings obtained from the ends of two stainless steel trunnions from LDEF and the prepared samples will be run on the University of Pennsylvania accelerator mass spectrometer. We have continued to investigate our discovery of naturally-occurring Be-10 contamination in bauxite and industrial aluminums from different sources. Measurements of Be-10 in ores from three different sites, and from four different samples of commercial aluminum have been made. Our investigators indicate that the contamination in commercial aluminum metal originates in its principal ore, bauxite. The levels in some bauxite samples were much greater than the maximum possible for in situ production by cosmic ray secondaries. Absorption of atmospheric Be-10 by surface ores exposed to rainfall is a reasonable explanation.

Company reference estimates for productivity loss due to migraine and productivity gains using rizatriptan 10 mg in Germany.

PubMed

Yoon, M-S; Katsarava, Z; Liedert, B; Krobot, K J; Diener, H C; Limmroth, V

2006-03-01

The prevalence of migraine in Germany is up to 14% in the female and up to 8% in the male population and peaks between the age of 35 and 45. Few studies have investigated the productivity loss and resulting costs attributable to migraine in Germany or addressed the question whether these costs can be reduced by optimal treatment. In recent years, 5-HT(1B/D) agonists (so-called triptans), a generation of drugs highly specific for migraine treatment, have been introduced. Seven 5-HT(1B/D) agonists have been approved in Germany with more than 20 dosage forms. We present a model that enables employers to estimate the annual cost of migraine and the annual cost that could be saved by treatment of migraine with rizatriptan compared with the use of non-specific antimigraine medication. A representative German company with 10,000 employees is used for the reference case analysis. This company is predicted to have 580 female and 284 male employees with migraine. These employees are estimated to lose 6992 workdays or 31.8 person years of productive effort annually due to migraine, valued approximately 1,431,719 euros. The value of work loss that could be avoided by treating migraine with rizatriptan is estimated at 619,094 euros annually. These data indicate that costs arising from lost productivity can be reduced by treating migraine headaches with a triptan.

Solar cycles and depositional processes in annual 10Be from two varved lake sediment records

NASA Astrophysics Data System (ADS)

Czymzik, Markus; Muscheler, Raimund; Brauer, Achim; Adolphi, Florian; Ott, Florian; Kienel, Ulrike; Dräger, Nadine; Słowiński, Michał; Aldahan, Ala; Possnert, Göran

2015-10-01

Beryllium 10 concentrations (10Becon) were measured at annual resolution from varved sediment cores of Lakes Tiefer See (TSK) and Czechowskie (JC) for the period 1983-2009 (∼solar cycles 22 and 23). Calibrating the 10Becon time-series against complementing proxy records from the same archive as well as local precipitation and neutron monitor data, reflecting solar forced changes in atmospheric radionuclide production, allowed (i) identifying the main depositional processes and (ii) evaluating the potential for solar activity reconstruction. 10Becon in TSK and JC sediments are significantly correlated to varying neutron monitor counts (TSK: r = 0.5, p = 0.05, n = 16; JC: r = 0.46, p = 0.03, n = 22). However, the further correlations with changes in organic carbon contents in TSK as well as varying organic carbon and detrital matter contents in JC point to catchment specific biases in the 10Becon time-series. In an attempt to correct for these biases multiple regression analysis was applied to extract an atmospheric 10Be production signal (10Beatmosphere). To increase the signal to noise ratio a 10Be composite record (10Becomposite) was calculated from the TSK and JC 10Beatmosphere time-series. 10Becomposite is significantly correlated to variations in the neutron monitor record (r = 0.49, p = 0.01, n = 25) and matches the expected amplitude changes in 10Be production between solar cycle minima and maxima. This calibration study on 10Be from two sites indicates the large potential but also, partly site-specific, limitations of 10Be in varved lake sediments for solar activity reconstruction.

Assessment of 10-Year Global Record of Aerosol Products from the OMI Near-UV Algorithm

NASA Astrophysics Data System (ADS)

Ahn, C.; Torres, O.; Jethva, H. T.

2014-12-01

Global observations of aerosol properties from space are critical for understanding climate change and air quality applications. The Ozone Monitoring Instrument (OMI) onboard the EOS-Aura satellite provides information on aerosol optical properties by making use of the large sensitivity to aerosol absorption and dark surface albedo in the UV spectral region. These unique features enable us to retrieve both aerosol extinction optical depth (AOD) and single scattering albedo (SSA) successfully from radiance measurements at 354 and 388 nm by the OMI near UV aerosol algorithm (OMAERUV). Recent improvements to algorithms in conjunction with the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) and Atmospheric Infrared Sounder (AIRS) carbon monoxide data also reduce uncertainties due to aerosol layer heights and types significantly in retrieved products. We present validation results of OMI AOD against space and time collocated Aerosol Robotic Network (AERONET) measured AOD values over multiple stations representing major aerosol episodes and regimes. We also compare the OMI SSA against the inversion made by AERONET as well as an independent network of ground-based radiometer called SKYNET in Japan, China, South-East Asia, India, and Europe. The outcome of the evaluation analysis indicates that in spite of the "row anomaly" problem, affecting the sensor since mid-2007, the long-term aerosol record shows remarkable sensor stability. The OMAERUV 10-year global aerosol record is publicly available at the NASA data service center web site (http://disc.sci.gsfc.nasa.gov/Aura/data-holdings/OMI/omaeruv_v003.shtml).

Examining the 10-Year Rebuilding Dilemma for U.S. Fish Stocks

PubMed Central

Patrick, Wesley S.; Cope, Jason

2014-01-01

Worldwide, fishery managers strive to maintain fish stocks at or above levels that produce maximum sustainable yields, and to rebuild overexploited stocks that can no longer support such yields. In the United States, rebuilding overexploited stocks is a contentious issue, where most stocks are mandated to rebuild in as short a time as possible, and in a time period not to exceed 10 years. Opponents of such mandates and related guidance argue that rebuilding requirements are arbitrary, and create discontinuities in the time and fishing effort allowed for stocks to rebuild due to differences in productivity. Proponents, however, highlight how these mandates and guidance were needed to curtail the continued overexploitation of these stocks by setting firm deadlines on rebuilding. Here we evaluate the statements made by opponents and proponents of the 10-year rebuilding mandate and related guidance to determine whether such points are technically accurate using a simple population dynamics model and a database of U.S. fish stocks to parameterize the model. We also offer solutions to many of the issues surrounding this mandate and its implementation by recommending some fishing mortality based frameworks, which meet the intent of the 10-year rebuilding requirement while also providing more flexibility. PMID:25375788

1 CFR 10.13 - Coverage of prior years.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 1 General Provisions 1 2012-01-01 2012-01-01 false Coverage of prior years. 10.13 Section 10.13 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.13 Coverage of prior years. The Administrative...

1 CFR 10.13 - Coverage of prior years.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 1 General Provisions 1 2014-01-01 2012-01-01 true Coverage of prior years. 10.13 Section 10.13 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.13 Coverage of prior years. The Administrative...

1 CFR 10.13 - Coverage of prior years.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 1 General Provisions 1 2013-01-01 2012-01-01 true Coverage of prior years. 10.13 Section 10.13 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.13 Coverage of prior years. The Administrative...

A 10-year analysis of South Carolina's industrial timber products output

Treesearch

Richard L. Welch; Thomas R. Bellamy

1979-01-01

The output of industrial timber products in South Carolina increased at an average annual rate of 2 percent between 1967 and 1976. Output from roundwood increased by 36 million cubic feet, while the output from plant byproducts increased 47 million cubic feet. Pulpwood was the leading roundwood product in the State throughout the period, followed by saw logs, and then...

Plant comparative genetics after 10 years.

PubMed

Gale, M D; Devos, K M

1998-10-23

The past 10 years have seen the discovery of unexpected levels of conservation of gene content and gene orders over millions of years of evolution within grasses, crucifers, legumes, some trees, and Solanaceae crops. Within the grasses, which include the three 500-million-ton-plus-per-year crops (wheat, maize, and rice), and the crucifers, which include all the Brassica crops, colinearity looks good enough to do most map-based cloning only in the small genome model species, rice and Arabidopsis. Elsewhere, knowledge gained in a few major crops is being pooled and applied across the board. The extrapolation of information from the well-studied species to orphan crops, which include many tropical species, is providing a solid base for their improvement. Genome rearrangements are giving new insights into evolution. In fact, comparative genetics is the key that will unlock the secrets of crop plants with genomes larger than that of humans.

Hepatitis C virus recurrence after liver transplantation: a 10-year evaluation.

PubMed

Gitto, Stefano; Belli, Luca Saverio; Vukotic, Ranka; Lorenzini, Stefania; Airoldi, Aldo; Cicero, Arrigo Francesco Giuseppe; Vangeli, Marcello; Brodosi, Lucia; Panno, Arianna Martello; Di Donato, Roberto; Cescon, Matteo; Grazi, Gian Luca; De Carlis, Luciano; Pinna, Antonio Daniele; Bernardi, Mauro; Andreone, Pietro

2015-04-07

To evaluate the predictors of 10-year survival of patients with hepatitis C recurrence. Data from 358 patients transplanted between 1989 and 2010 in two Italian transplant centers and with evidence of hepatitis C recurrence were analyzed. A χ(2), Fisher's exact test and Kruskal Wallis' test were used for categorical and continuous variables, respectively. Survival analysis was performed at 10 years after transplant using the Kaplan-Meier method, and a log-rank test was used to compare groups. A P level less than 0.05 was considered significant for all tests. Multivariate analysis of the predictive role of different variables on 10-year survival was performed by a stepwise Cox logistic regression. The ten-year survival of the entire population was 61.2%. Five groups of patients were identified according to the virological response or lack of a response to antiviral treatment and, among those who were not treated, according to the clinical status (mild hepatitis C recurrence, "too sick to be treated" and patients with comorbidities contraindicating the treatment). While the 10-year survival of treated and untreated patients was not different (59.1% vs 64.7%, P = 0.192), patients with a sustained virological response had a higher 10-year survival rate than both the "non-responders" (84.7% vs 39.8%, P < 0.0001) and too sick to be treated (84.7% vs 0%, P < 0.0001). Sustained virological responders had a survival rate comparable to patients untreated with mild recurrence (84.7% vs 89.3%). A sustained virological response and young donor age were independent predictors of 10-year survival. Sustained virological response significantly increased long-term survival. Awaiting the interferon-free regimen global availability, antiviral treatment might be questionable in selected subjects with mild hepatitis C recurrence.

26 CFR 1.59-1 - Optional 10-year writeoff of certain tax preferences.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Optional 10-year writeoff of certain tax... INCOME TAX INCOME TAXES Tax Preference Regulations § 1.59-1 Optional 10-year writeoff of certain tax... 59(e) applies to be deducted ratably over the 10-year period (3-year period in the case of...

26 CFR 1.59-1 - Optional 10-year writeoff of certain tax preferences.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Optional 10-year writeoff of certain tax... INCOME TAX INCOME TAXES Tax Preference Regulations § 1.59-1 Optional 10-year writeoff of certain tax... 59(e) applies to be deducted ratably over the 10-year period (3-year period in the case of...

Closure of logging wounds after 10 years

Treesearch

H. Clay Smith; Gary W. Miller; Thomas M. Schuler

1994-01-01

Closure of logging wounds on 96 sample trees was evaluated after 2, 5, and 10 years for Appalachian hardwood trees in north-central West Virginia. For yellow-poplar, northern red oak, black cherry, and white oak, many small wounds, 1 to 50 square inches in size, closed between 5 and 10 years after logging. For larger wounds, 50 to 200 square inches, it appears that...

Cosmogenic rare gases and 10-Be in a cross section of Knyahinya

NASA Technical Reports Server (NTRS)

Wieler, R.; Signer, P.; Herpers, U.; Sarafin, R.; Bonani, G.; Hofmann, H. J.; Morenzoni, E.; Nessi, M.; Suter, M.; Woelfli, W.

1986-01-01

The concentrations of cosmogenic nuclides were studied as a function of shielding on samples from a cross section of the 293 kg main fragment of the L5 chondrite Knyahinya. The stone broke into two nearly symmetrical parts upon its fall in 1866. The planar cross section has diameters between 40 and 55 cm. He, Ne, and Ar were measured on about 20 samples by mass spectrometry and the 10-Be activities on aliquots of 10 selected samples were determined by AMS. The 10-Be data are presented and the abundances of spallogenic nuclides are compared with the model calculations reported by Reedy for spherical L chondrites. The 10-Be production rates in Knyahinya are shown versus the shielding parameter 22-Ne/21-Ne.

Swift: 10 Years of Discovery

NASA Astrophysics Data System (ADS)

2014-12-01

The conference Swift: 10 years of discovery was held in Roma at La Sapienza University on Dec. 2-5 2014 to celebrate 10 years of Swift successes. Thanks to a large attendance and a lively program, it provided the opportunity to review recent advances of our knowledge of the high-energy transient Universe both from the observational and theoretical sides. When Swift was launched on November 20, 2004, its prime objective was to chase Gamma-Ray Bursts and deepen our knowledge of these cosmic explosions. And so it did, unveiling the secrets of long and short GRBs. However, its multi-wavelength instrumentation and fast scheduling capabilities made it the most versatile mission ever flown. Besides GRBs, Swift has observed, and contributed to our understanding of, an impressive variety of targets including AGNs, supernovae, pulsars, microquasars, novae, variable stars, comets, and much more. Swift is continuously discovering rare and surprising events distributed over a wide range of redshifts, out to the most distant transient objects in the Universe. Such a trove of discoveries has been addressed during the conference with sessions dedicated to each class of events. Indeed, the conference in Rome was a spectacular celebration of the Swift 10th anniversary. It included sessions on all types of transient and steady sources. Top scientists from around the world gave invited and contributed talks. There was a large poster session, sumptuous lunches, news interviews and a glorious banquet with officials attending from INAF and ASI. All the presentations, as well as several conference pictures, can be found in the conference website (http://www.brera.inaf.it/Swift10/Welcome.html). These proceedings have been collected owing to the efforts of Paolo D’Avanzo who has followed each paper from submission to final acceptance. Our warmest thanks to Paolo for all his work. The Conference has been made possible by the support from La Sapienza University as well as from the ARAP

Can we apply the 10Be/9Be flux tracer to marine sediments along glaciated margins?

NASA Astrophysics Data System (ADS)

Valletta, R. D.; Willenbring, J. K.; Passchier, S.; Elmi, C.

2016-12-01

Radioactive cosmogenic 10Be normalized to its stable isotope 9Be is proposed as a tracer of continental deposition into the marine basins throughout the Late Cenozoic. Close to glaciated margins, 10Be/9Be may reflect shifts in ice sheet dynamics whereby ice sheet retraction is accompanied by increases in freshwater discharge and terrestrial weathering, which may both increase 10Be and 9Be delivery to the continental shelf. However, this signal is complicated by boundary scavenging during periods of warmth and increased productivity. To disentangle the environmental and biological imprint on the 10Be/9Be isotope record, we sampled extensively characterized marine sedimentary packages offshore the Wilkes Subglacial Basin in an area where East Antarctic Ice Sheet (EAIS) retraction and advance is well-established (IODP U1361A). Combining this existing data with our new measurements creates a uniquely large, multi-proxy dataset for geochemical reconstructions along a glaciated margin. We measured 10Be, 9Be and a suite of bio-reactive transition metals from alternating diatom-rich and diatom-poor clay units 1) adsorbed to authigenic clays and 2) contained within diatom frustules, making this the first dataset of its kind. Diatom-rich clay sediments mark abrupt periods of Pliocene warming and a retracted EAIS. Beryllium co-varies with diatom-rich units: maximum 10Be ( 1.3 x 109 atoms g-1) and 9Be ( 300 ng g-1) peak during warmer intervals. These data mimic patterns observed in the nearby Ross Sea (Yokoyama et al., 2016), suggesting that interglacials are marked along glaciated margins by sudden pulses in Be delivery. By accounting for the Be inventory within diatoms, we have allowed for the exciting pairing of 10Be with 26Al to obtain 1) particle flux and 2) freshwater volume discharged from the EAIS during melting events. These values may offer an approach to constraining changes in two elusive parameters: subglacial erosion and ice sheet melt.

Functional outcome and health-related quality of life 10 years after moderate-to-severe traumatic brain injury.

PubMed

Andelic, N; Hammergren, N; Bautz-Holter, E; Sveen, U; Brunborg, C; Røe, C

2009-07-01

To describe the functional outcome and health-related quality of life (HRQL) 10 years after moderate-to-severe traumatic brain injury (TBI). A retrospective, population-based study of 62 survivors of working-age with moderate-to-severe TBI injured in 1995/1996, and hospitalized at the Trauma Referral Center in Eastern Norway. Functional status was measured by the Glasgow Outcome Scale-Extended (GOS-E). HRQL was assessed by the SF-36 questionnaire. The mean current-age was 40.8 years. The frequency of epilepsy was 19% and the depression rate 31%. A majority had good recovery (48%) or moderate disability (44%). Employment rate was 58%. Functional and employment status were associated with initial injury severity in contrast to HRQL. Study patients had significantly lower scores in all SF-36 dimensions when compared with the general Norwegian population. At 10-years follow-up, our study population is still in their most productive years and affected domains should be considered in long-term follow-up and intervention programs.

No vintage year ahead, but it will be better than '89

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garb, F.A.

1989-12-01

Activities in the upstream petroleum industry react to prices received for hydrocarbons and related products. Prices, in turn, are the result of supply, demand, politics and emotions. The author presents a forecast of 1990 oil industry activities and reviews the status of the pressures establishing oil and gas. According to this analysis, 1990 should be the first of a series of transition years. Oil and gas prices should be more stable than in the past. It will not be good drilling year, but will not be as bad as 1989. Gas exploration will again dominate exploration drilling. Development drilling willmore » account for more wells, if not for more budget dollars than exploration, with horizontal drilling developments being monitored closely industry-wide. Consolidation of mature producing properties into independent oil companies will continue. Decline in domestic production and an increase in hydrocarbon use and in imports should continue.« less

24 CFR 91.10 - Consolidated program year.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Consolidated program year. 91.10 Section 91.10 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development CONSOLIDATED SUBMISSIONS FOR COMMUNITY PLANNING AND DEVELOPMENT PROGRAMS General § 91.10...

Mitochondrial ROS Metabolism: 10 Years Later

PubMed Central

Kushnareva, Y. E.; Murphy, A. N.

2015-01-01

The role of mitochondria in oxidative stress is well recognized, but many questions are still to be answered. This article is intended to update our comprehensive review in 2005 by highlighting the progress in understanding of mitochondrial reactive oxygen species (ROS) metabolism over the past 10 years. We review the recently identified or re-appraised sources of ROS generation in mitochondria, such as p66shc protein, succinate dehydrogenase, and recently discovered properties of the mitochondrial antioxidant system. We also reflect upon some controversies, disputes, and misconceptions that confound the field. PMID:26071769

7 CFR 625.9 - 10-year restoration cost-share agreements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 6 2011-01-01 2011-01-01 false 10-year restoration cost-share agreements. 625.9... CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE WATER RESOURCES HEALTHY FORESTS RESERVE PROGRAM § 625.9 10-year... 10-year cost-share agreement and its terms are incorporated therein. (b) A 10-year cost-share...

IL10 single nucleotide polymorphisms are related to upregulation of constitutive IL-10 production and susceptibility to Helicobacter pylori infection.

PubMed

Assis, Shirleide; Marques, Cintia Rodrigues; Silva, Thiago Magalhães; Costa, Ryan Santos; Alcantara-Neves, Neuza Maria; Barreto, Mauricio Lima; Barnes, Kathleen Carole; Figueiredo, Camila Alexandrina

2014-06-01

Helicobacter pylori infection is a strong risk factor for gastric cancer, likely due to the extensive inflammation in the stomach mucosa caused by these bacteria. Many studies have reported an association between IL10 polymorphisms, the risk of gastric cancer, and IL-10 production. The aim of the study was to evaluate the association between IL10 genetic variants, Helicobacter pylori infection, and IL-10 production by peripheral blood leukocytes in children. We genotyped a total of 12 single nucleotide polymorphisms in IL10 in 1259 children aged 4-11 years living in a poor urban area in Salvador, Brazil, using TaqMan probe based, 5' nuclease assay minor groove binder chemistry. Association tests were performed by logistic regression for Helicobacter pylori infection and linear regression for IL-10 spontaneous production (whole-blood cultures) including sex, age, and principal components for informative ancestry markers as covariates, using PLINK. Our results shown that IL10 single nucleotide polymorphisms rs1800896 (OR = 1.63; 95% CI = 1.11-2.39), rs3024491 (OR = 1.71; 95% CI = 1.14-2.57), rs1878672 (OR = 1.79; 95% CI = 1.19-2.68), and rs3024496 (OR = 1.48; 95% CI = 1.05-2.08) were positively associated with Helicobacter pylori infection. Eight single nucleotide polymorphisms were associated with spontaneous production of IL-10 in culture, of which three (rs1800896 and rs1878672, p = .04; rs3024491, p = .01) were strongly associated with infection by Helicobacter pylori. Our results indicate that IL10 variants rs1800896, rs3024491, rs1878672, and rs3024496 are more consistently associated with the presence of anti-H. pylori IgG by inducing increased production of IL-10. Further studies are underway to elucidate the role of additional genetic variants and to investigate their impact on the occurrence of gastric cancer. © 2014 John Wiley & Sons Ltd.

A personal perspective and update on erosive tooth wear - 10 years on: Part 1 - Diagnosis and prevention.

PubMed

Bartlett, D

2016-08-12

Tooth wear has been recognised as an increasing problem over the past 10 years. Recent data from epidemiological studies indicate that the condition is common with prevalence of dentine exposure in adults ranging between 2% and 10% and visible surface changes on teeth observed up to 30% of European adults. The Basic Erosive Wear Examination (BEWE) was designed for general practitioners to score the severity using similar protocols as the Basic Periodontal Examination (BPE). The role of the BEWE is partly to increase awareness, but also a means to record the severity in the clinical notes. Over the past 10 years toothpaste manufacturers have launched products to prevent progression of erosive tooth wear using specially formulated fluorides or calcium based products. Probably the most important preventive advice is to reduce the frequency of acidic foods and drinks, particularly outside meal times.

Technology for Distance Education: A 10 Year Prospective.

ERIC Educational Resources Information Center

Bates, A. W.

This paper provides an overview of new technologies likely to be widely available within the next 10 years for teaching in Europe. It begins by presenting a framework which draws distinctions between different technologies based on their educational applications, i.e., for teaching or operational purposes, for communicating within or between…

Current state of coenzyme Q(10) production and its applications.

PubMed

Jeya, Marimuthu; Moon, Hee-Jung; Lee, Jeong-Lim; Kim, In-Won; Lee, Jung-Kul

2010-02-01

Coenzyme Q(10) (CoQ(10)), an obligatory cofactor in the aerobic respiratory electron transfer for energy generation, is formed from the conjugation of a benzoquinone ring with a hydrophobic isoprenoid chain. CoQ(10) is now used as a nutritional supplement because of its antioxidant properties and is beneficial in the treatment of several human diseases when administered orally. Bioprocesses have been developed for the commercial production of CoQ(10) because of its increased demand, and these bioprocesses depend on microbes that produce high levels of CoQ(10) naturally. However, as knowledge of the biosynthetic enzymes and the regulatory mechanisms modulating CoQ(10) production increases, approaches arise for the genetic engineering of CoQ(10) production in Escherichia coli and Agrobacterium tumefaciens. This review focused on approaches for CoQ(10) production, strategies used to engineer CoQ(10) production in microbes, and potential applications of CoQ(10).

Pluripotent stem cells: the last 10 years.

PubMed

Kimbrel, Erin A; Lanza, Robert

2016-12-01

Pluripotent stem cells (PSCs) can differentiate into virtually any cell type in the body, making them attractive for both regenerative medicine and drug discovery. Over the past 10 years, technological advances and innovative platforms have yielded first-in-man PSC-based clinical trials and opened up new approaches for disease modeling and drug development. Induced PSCs have become the foremost alternative to embryonic stem cells and accelerated the development of disease-in-a-dish models. Over the years and with each new discovery, PSCs have proven to be extremely versatile. This review article highlights key advancements in PSC research, from 2006 to 2016, and how they will guide the direction of the field over the next decade.

Simulating the mobility of meteoric 10Be in the landscape through a coupled soil-hillslope model (Be2D)

NASA Astrophysics Data System (ADS)

Campforts, Benjamin; Vanacker, Veerle; Vanderborght, Jan; Baken, Stijn; Smolders, Erik; Govers, Gerard

2016-04-01

Meteoric 10Be allows for the quantification of vertical and lateral soil fluxes over long time scales (103-105 yr). However, the mobility of meteoric 10Be in the soil system makes a translation of meteoric 10Be inventories into erosion and deposition rates complex. Here, we present a spatially explicit 2D model simulating the behaviour of meteoric 10Be on a hillslope. The model consists of two parts. The first component deals with advective and diffusive mobility of meteoric 10Be within the soil profile, and the second component describes lateral soil and meteoric 10Be fluxes over the hillslope. Soil depth is calculated dynamically, accounting for soil production through weathering as well as downslope fluxes of soil due to creep, water and tillage erosion. Synthetic model simulations show that meteoric 10Be inventories can be related to erosion and deposition across a wide range of geomorphological and pedological settings. Our results also show that meteoric 10Be can be used as a tracer to detect human impact on soil fluxes for soils with a high affinity for meteoric 10Be. However, the quantification of vertical mobility is essential for a correct interpretation of the observed variations in meteoric 10Be profiles and inventories. Application of the Be2D model to natural conditions using data sets from the Southern Piedmont (Bacon et al., 2012) and Appalachian Mountains (Jungers et al., 2009; West et al., 2013) allows to reliably constrain parameter values. Good agreement between simulated and observed meteoric 10Be concentrations and inventories is obtained with realistic parameter values. Furthermore, our results provide detailed insights into the processes redistributing meteoric 10Be at the soil-hillslope scale.

A Numerical Model to Assess Soil Fluxes from Meteoric 10Be Data

NASA Astrophysics Data System (ADS)

Campforts, B.; Govers, G.; Vanacker, V.; Vanderborght, J.; Smolders, E.; Baken, S.

2015-12-01

Meteoric 10Be may be mobile in the soil system. The latter hampers a direct translation of meteoric 10Be inventories into spatial variations in erosion and deposition rates. Here, we present a spatially explicit 2D model that allows us to simulate the behaviour of meteoric 10Be in the soil system. The Be2D model is then used to analyse the potential impact of human-accelerated soil fluxes on meteoric 10Be inventories. The model consists of two parts. A first component deals with advective and diffusive mobility of meteoric 10Be within the soil profile including particle migration, chemical leaching and bioturbation, whereas a second component describes lateral soil (and meteoric 10Be) fluxes over the hillslope. Soil depth is calculated dynamically, accounting for soil production through weathering and lateral soil fluxes from creep, water and tillage erosion. Model simulations show that meteoric 10Be inventories can indeed be related to erosion and deposition, across a wide range of geomorphological and pedological settings. However, quantification of the effects of vertical mobility is essential for a correct interpretation of the observed spatial patterns in 10Be data. Moreover, our simulations suggest that meteoric 10Be can be used as a tracer to unravel human impact on soil fluxes when soils have a high retention capacity for meteoric meteoric 10Be. Application of the Be2D model to existing data sets shows that model parameters can reliably be constrained, resulting in a good agreement between simulated and observed meteoric 10Be concentrations and inventories. This confirms the suitability of the Be2D model as a robust tool to underpin quantitative interpretations of spatial variability in meteoric 10Be data for eroding landscapes.

30 CFR 15.10 - Post-approval product audit.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Post-approval product audit. 15.10 Section 15... General Provisions § 15.10 Post-approval product audit. (a) Approved explosives and sheathed explosive... observe any tests conducted during this audit. (c) An approved explosive or sheathed explosive unit shall...

Low energy measurements of the 10B(p ,α )7Be reaction

NASA Astrophysics Data System (ADS)

Wiescher, M.; deBoer, R. J.; Görres, J.; Azuma, R. E.

2017-04-01

Background: The 11B(p,2 α ) 4He reaction is being discussed as a prime candidate for advanced aneutronic fusion fuel systems. Particular interest in this reaction has recently emerged for laser driven plasma systems for energy generation and jet-propulsion systems. The lack of long-lived radioactive reaction products has been suggested as the main advantage of proton-boron fusion fuel. However, 19% of natural boron is 10B, with the 10B(p ,α )7Be fusion reaction producing long-lived 7Be as a side product. Purpose: A detailed measurement of the 10B(p ,α )7Be reaction over the critical energy range of hot fusion plasma environments will help to determine the amount of 7Be radioactivity being produced. This information can be used in turn to monitor the actual fusion temperature by offline measurement of the extracted 7Be activity. The goal of the here presented experiment is to expand on the results of earlier experiments, covering a wider energy range of interest for aneutronic plasma fusion applications, including also both 10B(p ,α0)7Be and the 10B(p ,α1)7Be reaction channels. Method: The reaction cross section was measured over a wide energy range from Ep=400 to 1000 keV using particle detection and from Ep=80 to 1440 keV using γ -ray spectroscopic techniques. Reaction α particles were measured at different angles to obtain angular distribution information. The results are discussed in terms of an R -matrix analysis. Results: The cross section data cover a wider energy range than previously investigated and bridge a gap in the previously available data sets. The cross sections show good agreement with previous results in the low energy region and show that the 10B(p ,α0)7Be channel is considerably larger than that of the 10B(p ,α1)7Be channel up to Ep≈1 MeV . Conclusions: The new reaction data provides important new information about the reaction cross section over the entire energy range of plasma fusion facilities. This data, when coupled with

Projected and actual biomass production of 2- to 10- year-old intensively cultured Populus 'Tristis # 1'

Treesearch

J. Zavitkovski

1983-01-01

Intensively cultured plantations of Populus 'Tristis # 1' produce more than 10 mt/ha/year of woody biomass at most spacings as long as they are harvested when mean annual biomass increment (MABI) culminates. In addition, fully stocked plantations produce up to 4.4 mt/ha of leaf litter. Plantations of other poplar clones produce about 30% more woody biomass,...

10 years' experience with regular haemodialysis and renal transplantation.

PubMed Central

Chantler, C; Carter, J E; Bewick, M; Counahan, R; Cameron, J S; Ogg, C S; Williams, D G; Winder, E

1980-01-01

75 children aged under 15 years have entered the regular haemodialysis/renal transplant programme at Guy's Hospital in the 10 years since its inception; 13 children have subsequently died. A combination of hospital and home haemodialysis and renal transplantation was used. 64 children received 80 renal allografts; 37 1st grafts were from live, related donors and 27 were from cadaver donors. The 5-year acturial patient survival for the whole group and for those who had transplants was 76%. Live donor graft survival was 65% at 3 years, and 55% at 5 years; 1st cadaver graft survival was 42% at 3 years. Results obtained during the last 6 years of the 10-year period showed an improvement with a live related donor graft survival rate of 71%, and a 1st cadaver graft survival rate of 47% at 3 years. Particular experience was gained with home haemodialysis and live, related donor transplantation. Despite growth, and psychosocial and rehabilitation problems, the overall results were encouraging, particularly for the 46 children who had successful transplants. These children grew better, had fewer psychosocial difficulties, and were rehabilitated more successfully into normal life than those on long-term dialysis. We conclude that dialysis and transplantation should be offered to all suitable children with terminal renal failure. PMID:7002057

Tropical Andean and African glacier extent through the Holocene assessed with proglacial in situ 14C and 10Be measurements

NASA Astrophysics Data System (ADS)

Vickers, A. C.; Shakun, J. D.; Goehring, B. M.; Kelly, M. A.; Jackson, M. S.; Jomelli, V.

2017-12-01

We present measurements of the in situ cosmogenic radionuclides 14C and 10Be from recently exposed proglacial bedrock samples at the margin of the Quelccaya Ice Cap in Peru (n=5) and the Rwenzori mountains in Africa (n=3) to calculate cumulative exposure, burial, and erosion histories at these sites over the Holocene. The Holocene history (11 ka - present) of tropical glaciers gives important context to their observed retreat over the last century, insight into their sensitivity to climate forcing, and constraints on past climate change. Paired in situ 14C/10Be methods are used to exploit the multiple controls on nuclide concentrations and their differing half-lives (5730 years vs 1.38 Myr). In particular, the concentrations of both 14C and 10Be increase with exposure and decrease with glacial erosion; however,14C decreases not only due to glacial erosion, but also in appreciable amounts due to radio-decay during periods of burial as short as 800 years. Our results show similarities at both sites, with moderately high 10Be concentrations but 14C/10Be ratios approximately one-third of the production value, suggesting that both sites experienced several thousand years of exposure followed by burial during the mid-to-late Holocene. Our results are consistent with recently exposed subfossil plant remains at the Quelccaya margin that imply ice extended beyond its current position since 5.2 ka We will also present 10Be ages of several boulders from probable Little Ice Age moraines of the Charquini Sur Glacier in Bolivia (n=2) and Ritacuba Negro Glacier in Colombia (n=4) to better understand the timing of Little Ice Age advances in the tropical Andes.

The Flux of Galactic Cosmic Rays over the last 200,000 Years calculated from Beryllium-10 Records in deep Sea Sediments

NASA Astrophysics Data System (ADS)

Christl, M.; Strobl, C.; Mangini, A.; Kubik, P.

2003-04-01

The production of cosmogenic radionuclides like 10Be and 14C in the Earth's atmosphere is directly related to the flux of galactic cosmic rays (GCR) reaching the Earth's orbit. Measuring the depositional flux of 10Be, as deposited in marine sediments, therefore provides a good tool to reconstruct the GCR-flux and to study the presumed GCR-climate connection on millennial time scales. However, the deposition of 10Be into deep sea sediments also can be influenced strongly by climatically induced oceanic transport processes like sediment redistribution of adsorbed 10Be and lateral transport of dissolved 10Be. Consequently, the bulk deposition of 10Be can not be used to reconstruct the global GCR-flux. The global 10Be-production is separated from the transport signal by applying a correction procedure. While sediment redistribution is corrected by using the well established 230Thex-normalization methoda, the transport of dissolved 10Be is quantified by using a simple box model that is able to describe water mass transport and sedimentation of 10Be in the ocean. The transport-corrected 10Be-profiles represent global production changes. They can be used to calculate the flux of GCRs during the last 200,000 years (based on simulations presented by Masarik and Beerb). The comparison of the GCR-flux with climate records from stalagmites from lowc and midd latitudes shows a correlation between the growth periodes of stalagmites and times of low GCR-flux. The 10Be-based record of the GCR-flux also can be used in paleoclimate models to study the presumed GCR-climate connection on millennial timescales. begin{small} aFrank et al., in Use of Proxies in Paleoceanography: Examples from the South Atlantic (eds. Fischer, G. &Wefer, G.), 409-426 (Springer-Verlag, New York, 1999). bMasarik and Beer, Simulation of particle fluxes and cosmogenic nuclide production in the Earth's atmosphere. JGR-Atmospheres 104, 12099-12111 (1999). cNeff et al., Strong coherence between solar variability

Symptomatic oral lesions may be associated with contact allergy to substances in oral hygiene products.

PubMed

Larsen, K R; Johansen, J D; Reibel, J; Zachariae, C; Pedersen, A M L

2017-11-01

Dental materials and oral hygiene products may be responsible for oral contact allergic reactions. We aimed to determine the occurrence of allergies in patients with symptomatic oral lichen planus (OLP), oral lichenoid lesions (OLLs) and stomatitis and investigate if patch testing could identify contact allergies to dental materials and oral hygiene products in these patients. Forty-nine patients (7 men, 42 women) aged 31 to 77 years (61 ± 10.3 years) with symptomatic OLP, OLL or stomatitis and 29 healthy age- and gender-matched control subjects were included. They underwent an interview, clinical examination, oral mucosal biopsy and epicutan testing to the European baseline series, a toothpaste and dental material series. Nineteen patients had OLP, 19 OLL and 11stomatitis. Oral burning/itching was the most common symptom (83.7%), and 65.3% patients had more than one symptom. Patients visited their dentist more often than the healthy subjects and had statistically higher DMF-T and DMF-S scores. Nineteen patients (38.8%) and 10 healthy control subjects (34.5%) had allergic contact reactions primarily to fragrance ingredients. No differences could be found between OLP, OLL, stomatitis and healthy controls with regard to allergic contact reactions. However, contact allergy to aroma substances differed significantly between the patients and the healthy control subjects (p = 0.02). This type of contact allergy was most common in patients with OLP and OLL (p = 0.01). Avoidance cleared symptoms in all cases. Allergic reactions to aroma substances in oral hygiene products are common in patients with symptomatic OLP, OLL and stomatitis.

Federal R&D funding: 10-year trends

NASA Astrophysics Data System (ADS)

Bell, Peter M.

Research and development (R&D) funded by the federal government has grown steadily since 1971, according to the National Science Foundation (NSF). The total federal R&D funding gained at an annual rate of 8.6% in actual dollars. Substantial gains, on the order of 15% over 1981, had originally been planned but later revised downward, close to 0%, for the fiscal year 1982. The essential features of the 10-year trend are that federal R&D funding has been mostly directed toward the military—over twice the amount of all other types of R&D funding—and while military research funding is accelerating sharply, other research funding is on the decline. In simple terms, the 10-year increases are only for national defense.

Constraining processes of landscape change with combined in situ cosmogenic 14C-10Be analysis

NASA Astrophysics Data System (ADS)

Hippe, Kristina

2017-10-01

Reconstructing Quaternary landscape evolution today frequently builds upon cosmogenic-nuclide surface exposure dating. However, the study of complex surface exposure chronologies on the 102-104 years' timescale remains challenging with the commonly used long-lived radionuclides (10Be, 26Al, 36Cl). In glacial settings, key points are the inheritance of nuclides accumulated in a rock surface during a previous exposure episode and (partial) shielding of a rock surface after the main deglaciation event, e.g. during phases of glacier readvance. Combining the short-lived in situ cosmogenic 14C isotope with 10Be dating provides a valuable approach to resolve and quantify complex exposure histories and burial episodes within Lateglacial and Holocene timescales. The first studies applying the in situ14C-10Be pair have demonstrated the great benefit from in situ14C analysis for unravelling complex glacier chronologies in various glacial environments worldwide. Moreover, emerging research on in situ14C in sedimentary systems highlights the capacity of combined in situ14C-10Be analysis to quantify sediment transfer times in fluvial catchments or to constrain changes in surface erosion rates. Nevertheless, further methodological advances are needed to obtain truly routine and widely available in situ14C analysis. Future development in analytical techniques has to focus on improving the analytical reproducibility, reducing the background level and determining more accurate muonic production rates. These improvements should allow extending the field of applications for combined in situ14C-10Be analysis in Earth surface sciences and open up a number of promising applications for dating young sedimentary deposits and the quantification of recent changes in surface erosion dynamics.

Increased production of cosmogenic 10Be recorded in oceanic sediment sequences: Information on the age, duration, and amplitude of the geomagnetic dipole moment minimum over the Matuyama-Brunhes transition

NASA Astrophysics Data System (ADS)

Simon, Quentin; Thouveny, Nicolas; Bourlès, Didier L.; Bassinot, Franck; Savranskaia, Tatiana; Valet, Jean-Pierre; Aster Team

2018-05-01

New high-resolution authigenic 10Be/9Be ratio (Be-ratio) records covering the last geomagnetic reversal, i.e. the Matuyama-Brunhes transition (MBT), have been obtained and set on a time scale using benthic δ18O (Cibicides wuellerstorfi) records. The geographic distribution of the four studied sites allows global comparison between the North Atlantic, Indian and Pacific Oceans. All Be-ratio records contain a two-fold increase triggered by the geomagnetic dipole moment (GDM) collapse associated with the MBT. The stratigraphic position of the Be-ratio spike, relative to marine isotope stages, allows establishment of a robust astrochronological framework for the MBT, anchoring its age between 778 and 766 ka (average mid-peaks at 772 ka), which is consistent with all other available 10Be-proxy records from marine, ice and loess archives. The global 10Be atmospheric production doubling represents an increase of more than 300 atoms m-2 s-1 that is compatible with the increased magnitude of atmospheric 10Be production obtained by simulations between the present GDM and a null-GDM. The minimum 10Be-derived GDM average computed for the 776-771 ka interval is 1.7 ± 0.4 ×1022 Am2, in agreement with model simulations and absolute paleointensities of transitional lava flows.

40 CFR 422.10 - Applicability; description of the phosphorus production subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... phosphorus production subcategory. 422.10 Section 422.10 Protection of Environment ENVIRONMENTAL PROTECTION... Phosphorus Production Subcategory § 422.10 Applicability; description of the phosphorus production... production of phosphorus and ferrophosphorus by smelting of phosphate ore. ...

40 CFR 422.10 - Applicability; description of the phosphorus production subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... phosphorus production subcategory. 422.10 Section 422.10 Protection of Environment ENVIRONMENTAL PROTECTION... Phosphorus Production Subcategory § 422.10 Applicability; description of the phosphorus production... production of phosphorus and ferrophosphorus by smelting of phosphate ore. ...

GENIE Production Release 2.10.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alam, M.; Andreopoulos, C.; Athar, M.

2015-12-25

GENIE is a neutrino Monte Carlo event generator that simulates the primary interaction of a neutrino with a nuclear target, along with the subsequent propagation of the reaction products through the nuclear medium. It additionally contains libraries for fully-featured detector geometries and for managing various types of neutrino flux. This note details recent updates to GENIE, in particular, changes introduced into the newest production release, version 2.10.0.

Perceived Partner Responsiveness Predicts Diurnal Cortisol Profiles 10 Years Later.

PubMed

Slatcher, Richard B; Selcuk, Emre; Ong, Anthony D

2015-07-01

Several decades of research have demonstrated that marital relationships have a powerful influence on physical health. However, surprisingly little is known about how marriage affects health--both in terms of psychological processes and biological ones. Over a 10-year period, we investigated the associations between perceived partner responsiveness--the extent to which people feel understood, cared for, and appreciated by their romantic partners--and diurnal cortisol in a large sample of married and cohabitating couples in the United States. Partner responsiveness predicted higher cortisol values at awakening and steeper (i.e., healthier) cortisol slopes at the 10-year follow-up. These associations remained strong after we controlled for demographic factors, depressive symptoms, agreeableness, and other positive and negative relationship factors. Furthermore, declines in negative affect over the 10-year period mediated the prospective association between responsiveness and cortisol slope. These findings suggest that diurnal cortisol may be a key biological pathway through which social relationships affect long-term health. © The Author(s) 2015.

Validation of 10-year SAO OMI ozone profile (PROFOZ) product using Aura MLS measurements

NASA Astrophysics Data System (ADS)

Huang, Guanyu; Liu, Xiong; Chance, Kelly; Yang, Kai; Cai, Zhaonan

2018-01-01

We validate the Ozone Monitoring Instrument (OMI) ozone profile (PROFOZ v0.9.3) product including ozone profiles between 0.22 and 261 hPa and stratospheric ozone columns (SOCs) down to 100, 215, and 261 hPa from October 2004 through December 2014 retrieved by the Smithsonian Astrophysical Observatory (SAO) algorithm against the latest Microwave Limb Sound (MLS) v4.2x data. We also evaluate the effects of OMI row anomaly (RA) on the retrieval by dividing the data set into before and after the occurrence of serious RA, i.e., pre-RA (2004-2008) and post-RA (2009-2014). During the pre-RA period, OMI ozone profiles agree very well with MLS data. After applying OMI averaging kernels to MLS data, the global mean biases (MBs) are within 3 % between 0.22 and 100 hPa, negative biases are within 3-9 % for lower layers, and the standard deviations (SDs) are 3.5-5 % from 1 to 40 hPa, 6-10 % for upper layers, and 5-20 % for lower layers. OMI shows biases dependent on latitude and solar zenith angle (SZA), but MBs and SDs are mostly within 10 % except for low and high altitudes of high latitudes and SZAs. Compared to the retrievals during the pre-RA period, OMI retrievals during the post-RA period degrade slightly between 5 and 261 hPa with MBs and SDs typically larger by 2-5 %, and degrade much more for pressure less than ˜ 5 hPa, with larger MBs by up to 8 % and SDs by up to 15 %, where the MBs are larger by 10-15 % south of 40° N due to the blockage effect of RA and smaller by 15-20 % north of 40° N due to the solar contamination effect of RA. The much worse comparisons at high altitudes indicate the UV1 channel of pixels that are not flagged as RA is still affected by the RA. During the pre-RA period, OMI SOCs show very good agreement with MLS data with global mean MBs within 0.6 % and SDs of 1.9 % for SOCs down to 215 and 261 hPa and of 2.30 % for SOC down to 100 hPa. Despite clearly worse ozone profile comparisons during the post-RA period, OMI SOCs only slightly degrade

Maximal exercise testing variables and 10-year survival: fitness risk score derivation from the FIT Project.

PubMed

Ahmed, Haitham M; Al-Mallah, Mouaz H; McEvoy, John W; Nasir, Khurram; Blumenthal, Roger S; Jones, Steven R; Brawner, Clinton A; Keteyian, Steven J; Blaha, Michael J

2015-03-01

To determine which routinely collected exercise test variables most strongly correlate with survival and to derive a fitness risk score that can be used to predict 10-year survival. This was a retrospective cohort study of 58,020 adults aged 18 to 96 years who were free of established heart disease and were referred for an exercise stress test from January 1, 1991, through May 31, 2009. Demographic, clinical, exercise, and mortality data were collected on all patients as part of the Henry Ford ExercIse Testing (FIT) Project. Cox proportional hazards models were used to identify exercise test variables most predictive of survival. A "FIT Treadmill Score" was then derived from the β coefficients of the model with the highest survival discrimination. The median age of the 58,020 participants was 53 years (interquartile range, 45-62 years), and 28,201 (49%) were female. Over a median of 10 years (interquartile range, 8-14 years), 6456 patients (11%) died. After age and sex, peak metabolic equivalents of task and percentage of maximum predicted heart rate achieved were most highly predictive of survival (P<.001). Subsequent addition of baseline blood pressure and heart rate, change in vital signs, double product, and risk factor data did not further improve survival discrimination. The FIT Treadmill Score, calculated as [percentage of maximum predicted heart rate + 12(metabolic equivalents of task) - 4(age) + 43 if female], ranged from -200 to 200 across the cohort, was near normally distributed, and was found to be highly predictive of 10-year survival (Harrell C statistic, 0.811). The FIT Treadmill Score is easily attainable from any standard exercise test and translates basic treadmill performance measures into a fitness-related mortality risk score. The FIT Treadmill Score should be validated in external populations. Copyright © 2015 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

10Be measured in a GRIP snow pit and modeled using the ECHAM5-HAM general circulation model

NASA Astrophysics Data System (ADS)

Heikkilä, U.; Beer, J.; Jouzel, J.; Feichter, J.; Kubik, P.

2008-03-01

10Be measured in a Greenland Ice Core Project (GRIP) snow pit (1986-1990) with a seasonal resolution is compared with the ECHAM5-HAM GCM run. The mean modeled 10Be concentration in ice (1.0.104 atoms/g) agrees well with the measured value (1.2.104 atoms/g). The measured 10Be deposition flux (88 atoms/m2/s) also agrees well with the modeled flux (69 atoms/m2/s) and the measured precipitation rate (0.67 mm/day) agrees with the modeled rate (0.61 mm/day). The mean surface temperature of -31°C estimated from δ 18O is lower than the temperature measured at a near-by weather station (-29°C) and the modeled temperature (-26°C). During the 5-year period the concentrations and deposition fluxes, both measured and modeled, show a decreasing trend consistent with the increase in the solar activity. The variability of the measured and modeled concentrations and deposition fluxes is very similar suggesting that the variability is linked to a variability in production rather than the local meteorology.

An 18-year-old man with recurrent pneumothorax since he was 10-year-old.

PubMed

Demir, Meral; Çobanoğlu, Nazan

2016-12-01

An 18-year-old male patient was referred to the department of pediatric pulmonology with a history of recurrent pneumothorax. Initial pneumothorax occurred at the age of 10. Following diagnosis of congenital lobar emphysema, he had five episodes of pneumothorax and subsequently underwent right-lower lobe anterobasal segmentectomy. Based on thoracic computed tomography (CT) and clinical manifestation, Birt-Hogg-Dube (BHD) syndrome was suspected and confirmed following genetic testing. BHD syndrome is a rare tumor predisposition syndrome first described in 1977. The syndrome is characterized by skin fibrofolliculomas, lung cysts, recurrent spontaneous pneumothorax, and renal cell cancer. The underlying cause is a germline mutation in the folliculin (FLCN) gene located on chromosome 17p11.2. Clinical manifestation usually appears after the age of 20 years. In this case, we report a case of BHD with episodes of recurrent pneumothorax, the first of which occurred at the age of 10 years. Pulmonologists should be aware of this syndrome in patients with a personal and family history of pneumothoraces and CT findings of multiple pulmonary cysts as additional evaluation and testing may be warranted. Pediatr Pulmonol. 2016;51:E41-E43. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

A bibliometric analysis of toxicology research productivity in Middle Eastern Arab countries during a 10-year period (2003-2012).

PubMed

Zyoud, Sa'ed H; Al-Jabi, Samah W; Sweileh, Waleed M; Awang, Rahmat

2014-01-21

Bibliometric studies are increasingly being used for research assessment by involving the application of statistical methods to scientific publications to obtain the bibliographics for each country. The main objective of this study was to analyse the research productivity originating from 13 Middle Eastern Arab (MEA) countries with articles published in toxicology journals. Data from January 1, 2003 till December 31, 2012 were searched for documents with specific words in the toxicology field as a "source title" in any one of the 13 MEA countries. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies. Research productivity was adjusted to the national population and nominal gross domestic product (GDP) per capita. Documents (n = 1,240) were retrieved from 73 international peer-reviewed toxicology journals. The h-index of the retrieved documents was 39. Of the 73 journal titles, 52 (69.9%) have their IF listed in the ISI Journal Citation Reports 2012; 198 documents (16.0%) were published in journals that had no official IF. After adjusting for economy and population power, Egypt (193.6), Palestine (18.1), Kingdom of Saudi Arabia (KSA) (13.0), and Jordan (11.5) had the highest research productivity. Countries with large economies, such as the Kuwait, United Arab Emirates (UAE), and Oman, tended to rank relatively low after adjustment of GDP. The total number of citations at the time of data analysis (August 4, 2013) was 10,991, with a median (interquartile range) of 4 (1-11). MEA collaborated more with countries in the MEA regions (16.7%), especially KSA, Egypt, and UAE, followed by Europe (14.4%), especially with the United Kingdom and Germany. The present data show a promising rise and a good start for toxicology research activity in toxicology journals in the Arab world. Research output is low in some countries, which can be improved by investing in more international and national collaborative research

One year test-retest reliability of neurocognitive baseline scores in 10- to 12-year olds.

PubMed

Moser, Rosemarie Scolaro; Schatz, Philip; Grosner, Emily; Kollias, Kelly

2017-01-01

How often youth athletes 10-12 years of age should undergo neurocognitive baseline testing remains an unanswered question. We sought to examine the test-retest reliability of annual ImPACT data in a sample of middle school athletes. Participants were 30 youth athletes, ages 10-12 years (Mean = 11.6, SD = 0.6) selected from a larger database of 10-18 year old athletes, who completed two consecutive annual baseline evaluations using the online version of ImPACT. Athlete assent and parental consent were obtained for all participants. Assessments were conducted either individually or in small groups of 2 to 3 athletes, under the supervision of a neuropsychologist or post-doctoral fellow. Test-retest coefficients were as follows: Verbal Memory .71, Visual Memory .35, Visual Motor Speed .69, Reaction Time .34. Intra-class Correlation Coefficients (single/average) were as follows: Verbal Memory .70/.83, Visual Memory .35/.52, Visual Motor Speed .69/.82, Reaction Time .34/.50. Regression-based measures to correct for practice effects revealed that only a small percentage of cases fell outside 90 and 95% confidence intervals, reflecting stability across assessments. Findings indicate that test-retest reliability of Verbal Memory and Visual Motor Speed are generally stable in 10-12 year old athletes. Nevertheless, Visual Memory Index, Reaction Time Index, and Symptom Checklist scores appear to be less reliable over time, especially compared to published data on high school athletes, suggesting the utility of re-testing on an annual basis in this younger age group.

Drowning in Pretoria, South Africa: A 10-year review.

PubMed

Morris, N K; du Toit-Prinsloo, L; Saayman, G

2016-01-01

Drowning is classified as the 3rd leading cause of accidental deaths worldwide and is deemed to be a preventable cause of death. Bodies retrieved from a water medium pose several challenges to the forensic pathologist with the diagnosis of drowning being primarily one of exclusion. The aim of this study was to do a retrospective descriptive case audit of bodies retrieved from water and immersion related deaths, which were investigated at the Pretoria Medico-Legal Laboratory (PMLL) over a 10 year period (January 2002 through December 2011). A total of 346 cases were identified for inclusion into this study. In 6% (20) of these cases, the death was not related to drowning; in 14% (48) no clear cause of death could be ascertained and in 278 cases (80%) the cause of death was considered to have been due to drowning. Infants (under 1 year, of age) constituted 41 (15%) of the cases; toddlers (aged 1-2 years) comprised 52 (19%) cases; children (aged 2-13 years) 49 (18%) cases; adolescents (aged 13-18 years) comprised 10 (3%) cases; adults (above 18, years) made up 126 (45%) of the cases. The majority of the drownings, occurred in swimming pools [125 cases (38%)]. In infants 23 (56%) of, drownings occurred in swimming pools followed by buckets [7 cases (17%)]. Sixty-nine per cent of toddler drownings (36 cases) occurred in swimming, pools. In the adult population, 40 (32%) of cases occurred in pools and 35 cases (28%) in rivers. Positive blood alcohol results were recorded in 48, (42%) out of 113 cases where the test was requested, 40 (35%) of these, cases higher than 0.05 g per 100 ml. This study suggests that many drowning deaths in Pretoria may be preventable by introducing greater public awareness of the risks and instituting relatively simple, protective measures. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Analytical similarity assessment of rituximab biosimilar CT-P10 to reference medicinal product

PubMed Central

Lee, Kyoung Hoon; Kim, Yeon Jung; Kang, Hyun Ah; Kim, Sung Hwan; Lee, So Jung; Lim, Ki Jung; Jung, Soon Kwan; Chang, Shin Jae

2018-01-01

ABSTRACT CT-P10 (Truxima™) was recently approved as the world's first rituximab biosimilar product in the European Union (EU) and South Korea. To demonstrate biosimilarity of CT-P10 with the reference medicinal product (RMP), extensive 3-way similarity assessment has been conducted between CT-P10, EU-Rituximab and US-Rituximab, focusing on the physicochemical and biological quality attributes. A multitude of state-of-the-art analyses revealed that CT-P10 has identical primary and higher order structures compared to the original product. Purity/impurity profiles of CT-P10 measured by the levels of aggregates, fragments, non-glycosylated form and process-related impurities were also found to be comparable with those of RMPs. In terms of the post-translational modification, CT-P10 contains slightly less N-terminal pyro-glutamate variant, which has been known not to affect product efficacy or safety. Oligosaccharide profiling has revealed that, although CT-P10 contains the same conserved glycan species and relative proportion with the RMPs, the content of total afucosylated glycan in CT-P10 was slightly higher than in EU- or US-Rituximab. Nevertheless, the effect of the observed level of afucosylation in CT-P10 drug product on Fc receptor binding affinity or antibody-dependent cell-mediated cytotoxicity was found to be negligible based on the spiking study with highly afucosylated sample. Arrays of biological assays representative of known and putative mechanisms of action for rituximab have shown that biological activities of CT-P10 are within the quality range of RMPs. Recent results of clinical studies have further confirmed that the CT-P10 exhibits equivalent clinical efficacy and safety profiles compared to EU- and US-Rituximab. The current 3-way similarity assessment together with clinical study results confidently demonstrate that CT-P10 is highly similar with EU- and US-Rituximab in terms of physicochemical properties, biological activities, efficacy, and

Analytical similarity assessment of rituximab biosimilar CT-P10 to reference medicinal product.

PubMed

Lee, Kyoung Hoon; Lee, Jihun; Bae, Jin Soo; Kim, Yeon Jung; Kang, Hyun Ah; Kim, Sung Hwan; Lee, So Jung; Lim, Ki Jung; Lee, Jung Woo; Jung, Soon Kwan; Chang, Shin Jae

2018-04-01

CT-P10 (Truxima™) was recently approved as the world's first rituximab biosimilar product in the European Union (EU) and South Korea. To demonstrate biosimilarity of CT-P10 with the reference medicinal product (RMP), extensive 3-way similarity assessment has been conducted between CT-P10, EU-Rituximab and US-Rituximab, focusing on the physicochemical and biological quality attributes. A multitude of state-of-the-art analyses revealed that CT-P10 has identical primary and higher order structures compared to the original product. Purity/impurity profiles of CT-P10 measured by the levels of aggregates, fragments, non-glycosylated form and process-related impurities were also found to be comparable with those of RMPs. In terms of the post-translational modification, CT-P10 contains slightly less N-terminal pyro-glutamate variant, which has been known not to affect product efficacy or safety. Oligosaccharide profiling has revealed that, although CT-P10 contains the same conserved glycan species and relative proportion with the RMPs, the content of total afucosylated glycan in CT-P10 was slightly higher than in EU- or US-Rituximab. Nevertheless, the effect of the observed level of afucosylation in CT-P10 drug product on Fc receptor binding affinity or antibody-dependent cell-mediated cytotoxicity was found to be negligible based on the spiking study with highly afucosylated sample. Arrays of biological assays representative of known and putative mechanisms of action for rituximab have shown that biological activities of CT-P10 are within the quality range of RMPs. Recent results of clinical studies have further confirmed that the CT-P10 exhibits equivalent clinical efficacy and safety profiles compared to EU- and US-Rituximab. The current 3-way similarity assessment together with clinical study results confidently demonstrate that CT-P10 is highly similar with EU- and US-Rituximab in terms of physicochemical properties, biological activities, efficacy, and safety for

'FIFA 11 for Health' for Europe. 1: effect on health knowledge and well-being of 10- to 12-year-old Danish school children.

PubMed

Fuller, Colin W; Ørntoft, Christina; Larsen, Malte Nejst; Elbe, Anne-Marie; Ottesen, Laila; Junge, Astrid; Dvorak, Jiri; Krustrup, Peter

2017-10-01

To modify the 'FIFA 11 for Health' programme to the European situation, and to assess its effects on health knowledge and well-being in Danish school children. A two-cohort study with seven intervention and two control schools. Of the 546 Danish children (boys 269; girls 277) of mean age 11.1 (±0.4) years from five city and four country-side schools, 402 undertook the 'FIFA 11 for Health' programme and 144 acted as controls. As part of each school's PE curriculum, seven intervention schools received a 45 min Play Football period (football skills and 3 vs 3 games) and a 45 min Play Fair period (health issues and football drills) on a weekly-basis for 11 weeks. Control participants continued with their regular school PE activities. Participants completed preintervention and postintervention health knowledge and well-being questionnaires. Overall, health knowledge increase was significantly (p<0.05) greater for the intervention group (11.9%) than the control group (2.6%). Significant (p<0.05) between-group differences were obtained for 8 of 10 health topics (6.1-20.2%) related to physical activity, nutrition, hygiene and well-being. The social dimension of the well-being questionnaire was significantly (p<0.05) improved in the intervention group compared to the control group, but there were no significant between-group effects for the physical, emotional and school dimensions. Positive reporting about the programme was given by 72.4% of the children and only 4.8% reported negatively. The 'FIFA 11 for Health' programme modified for Europe demonstrated positive effects on children's health knowledge and social dimension of well-being, thereby providing evidence that the football-based health education programme can be used effectively within a European school's curriculum to increase physical activity, well-being and health knowledge. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Chronic pain in multiple sclerosis: A 10-year longitudinal study.

PubMed

Young, Jamie; Amatya, Bhasker; Galea, Mary P; Khan, Fary

2017-07-01

as it could be'. Pain types were similar to 7-years follow-up but remained higher than baseline. There was a significant deterioration in quality of life in those with more severe CPG over time. Almost half of the participants 31 (44%) required care either from a private carer, institution or from a family member. Although fear of taking medications and side effects were common barriers to treatment for pain, there was an increase in the use of pharmacological treatment over time and an increase in the use of healthcare services, mainly neurologists and general practitioners. The pain measures reported by the participants were similar to those at the 7-year follow-up except there was a greater representation of bilateral pain locations (limb, trunk and facial pain) compared to baseline and 7-year follow-up. At 10-year follow-up, more participants used medications compared to 7-year follow-up and there was an increase in the use of health professionals at the 10-year follow-up. At the 10-year follow up QoL of the participants deteriorated significantly and more participants had progressed to higher CPG III and CPG IV. This study demonstrates that chronic pain is a significant issue over time in MS, with clinical and health implications, impact on quality of life, disability and healthcare utilization. Greater awareness of chronic pain in pwMS, cognitive classifications and an interdisciplinary approach is required to improve long-term patient outcomes and well-being. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

10Be accumulation in a soil chronosequence

USGS Publications Warehouse

Pavich, M.J.; Brown, L.; Klein, J.; Middleton, R.

1984-01-01

We have measured the concentration of the cosmogenic isotope 10Be in soil samples from various horizons at six sites, including three independently dated Rappahannock River terraces and a previously undated Piedmont soil to which we have assigned an age. All of the incident 10Be can be accounted for in one of these soils and a second is within a factor of two. In three soils, whose concentrations vary widely with depth, a significant fraction of the incident 10Be cannot be accounted for. Incomplete sampling, and enhanced Be mobility caused by organic components, are the probable reasons for the low inventory of Be from these three soils. Overall, the data from these six sites indicate that 10Be accumulation could be used to assign ages to soils if Be is not mobilized and lost from the soil profile. ?? 1984.

Responses to televised alcohol advertisements associated with drinking behaviour of 10-17-year-olds.

PubMed

Wyllie, A; Zhang, J F; Casswell, S

1998-03-01

To examine the nature of the relationships between 10-17-year-old New Zealanders' responses to alcohol advertisements and their drinking behaviour and future drinking expectations, with consideration also being given to the role of positive and negative beliefs about drinking. Survey involving 500 face-to-face interviews, with selection based on random cluster sampling. In respondents' homes in New Zealand's three largest urban areas. Ten-17-year-old New Zealanders. Response to specific alcohol advertisements was measured by recalled exposure (how often they recalled having seen the advertisements) and liking (a measure of positive response). An exploratory structural equation model provided tentative support for the theory-based hypothesis that positive responses to beer advertisements increased the frequency of current drinking and expected future drinking, among this age group. There was no evidence for the hypothesized reciprocal effects; the frequency of drinking (including non-drinking) did not significantly affect the respondent's liking of beer advertisements. There was also no support for a hypothesis that linking of the beer advertisements was a product of a general liking for alcohol. Many of the young people themselves felt that alcohol advertising encouraged teenagers to drink. This was especially the case among 10-13-year-old males, who were the most likely to accept the portrayals in alcohol advertising as realistic. Although there are limitations on the confidence with which conclusions can be drawn, the findings are consistent with qualitative and quantitative research and different theoretical perspectives on advertising processes which suggest alcohol advertising is likely to have some influence on young people.

River fluxes to the sea from the ocean's 10Be/9Be ratio

NASA Astrophysics Data System (ADS)

von Blanckenburg, F.; Bouchez, J.

2013-12-01

The ratio of the meteoric cosmogenic radionuclide 10Be to the stable isotope 9Be is proposed here to be a flux proxy of terrigenous input into the oceans. The ocean's dissolved 10Be/9Be is set by (1) the flux of meteoric 10Be produced in the atmosphere; (2) the denudational flux of the rivers discharging into a given ocean basin; (3) the fraction of 9Be that is released from primary minerals during weathering (meaning the 9Be transported by rivers in either the dissolved form or adsorbed onto sedimentary particles and incorporated into secondary oxides); and (4) the fraction of riverine 10Be and 9Be actually released into seawater. Using published 10Be/9Be data of rivers for which independent denudation rate estimates exist we first find that the global average fraction of 9Be released during weathering into river waters and their particulate load is 20% and does not depend on denudation rate. We then evaluate this quantitative denudation rate proxy by using published dissolved seawater Be isotope data and a compilation of global river loads (15Gt/yr). We find that the measured global average oceanic dissolved 10Be/9Be ratio of about 0.9E-7 is satisfied by the mass balance if only 6.5% of the dissolved and reactive riverine Be is eventually released to the open ocean by boundary exchange. Except for the South Atlantic and the South Pacific, in which the 10Be/9Be ratio is dominated by Be advected through ocean circulation, good agreement results between 10Be/9Be ratios predicted by denudation rates and measured ocean 10Be/9Be ratios when we establish this mass balance for individual ocean basins. As the seawater 10Be/9Be ratio is faithfully recorded in marine chemical precipitates the 10Be/9Be ratio extracted from authigenic sediments can now serve to estimate relative changes in terrigenous input into the oceans back through time on a global and on a basin scale.

Brunhes-Matuyama Magnetic Polarity Reversal Tracing using Chinese loess10Be

NASA Astrophysics Data System (ADS)

Zhou, W.; Beck, W.; Kong, X.; An, Z.; Qiang, X.; Wu, Z.; Xian, F.; Ao, H.

2014-12-01

The geomagnetic polarity reversal is generally considered to occur synchronously around the world, and is commonly used as a time marker. However, in the case of the most recent reversal, the Brunhes-Matuyama (B-M) reversal (~780 ka), comparison of paleomagnetic studies in Chinese loess-paleosol sequences versus marine sediments revealed a marked discrepancy in timing of this event (Tauxe et al., 1996; Zhou and Shackleton, 1999), leading to the debate on uncertainties of paleoclimatic correlation between the Chinese loess-paleosol sequences and marine sediments (Wang et al., 2006; Liu et al., 2008; Jin and Liu, 2011). Based on this issue, here we propose to use the cosmogenic 10Be to address this conundrum. 10Be is a long-lived radionuclide produced in the atmosphere by cosmic ray spallation reactions and carried to the ground attached to aerosols. Its atmospheric production rate is inversely proportional to the geomagnetic field intensity (Masarik and Beer, 1999). This allows us to reconstruct past geomagnetic field intensity variations using 10Be concentrations recorded in different sedimentary archives. We carried out the 10Be studies in Luochuan and Xifeng sections in Chinese Loess Plateau, both loess profiles show that 10Be production rate was at a maximum-an indication of the dipole field reversal-at ca. 780 ± 3 ka BP., in paleosol unit S7corresponding to MIS 19. These results have proven that the timing of B-M reversal recorded in Chinese loess is synchronous with that seen in marine records (Tauxe et al., 1996) and reaffirmed the conventional paleoclimatic correlation of loess-paleosol sequences with marine isotope stages and the standard loess timescale as correct. However, it is ~25 ka younger than the age (depth) of the magnetic polarity reversal recorded in these same Chinese loess-paleosol sequences, demonstrating that loess magnetic overprinting has occurred. 1.Jin, C.S.,et al., 2011,PALAEOGEOGR PALAEOCL, 299, 309-3172.Liu, Q.S., et al., 2008, EARTH

Productivity change of surgeons in an academic year.

PubMed

Nakata, Yoshinori; Watanabe, Yuichi; Otake, Hiroshi; Nakamura, Toshihito; Oiso, Giichiro; Sawa, Tomohiro

2015-01-01

The goal of this study was to calculate total factor productivity of surgeons in an academic year and to evaluate the effect of surgical trainees on their productivity. We analyzed all the surgical procedures performed from April 1 through September 30, 2013 in the Teikyo University Hospital. The nonradial and nonoriented Malmquist model under the variable returns-to-scale assumptions was employed. A decision-making unit is defined as a surgeon with the highest academic rank in the surgery. Inputs were defined as the number of physicians who assisted in surgery, and the time of surgical operation from skin incision to skin closure. The output was defined as the surgical fee for each surgery. April is the beginning month of a new academic year in Japan, and we divided the study period into April to June and July to September 2013. We computed each surgeon's Malmquist index, efficiency change, and technical change. We analyzed 2789 surgical procedures that were performed by 105 surgeons. The Malmquist index of all surgeons was significantly greater than 1 (p = 0.0033). The technical change was significantly greater than 1 (p < 0.0001). However, the efficiency change was not statistically significantly different from 1 (p = 0.1817). The surgeons are less productive in the beginning months of a new academic year. The main factor of this productivity loss is considered to be surgical training. Copyright © 2014 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

Oblique metatarsal osteotomy for intractable plantar keratosis: 10-year follow-up.

PubMed

Idusuyi, O B; Kitaoka, H B; Patzer, G L

1998-06-01

Twenty patients (14 women and 6 men) (23 feet) had a single oblique osteotomy operation of the 2nd, 3rd, or 4th metatarsal without fixation during an 8-year period. The mean age was 46 years (range, 21-64 years). Each patient had a painful intractable plantar keratosis preoperatively. The average follow-up was 10 years (range, 3-14 years). Postoperatively, reoperation was performed in four feet because of painful callosities. For 13 of the 19 feet that did not have reoperation, patients were limited in footwear or required a shoe insert. Overall results were good for 10 feet, fair for 7 feet, and poor for 6 feet. The only complication was a deep infection that occurred in one foot (good result). Nonunion occurred in one foot and delayed union in one. The average decrease in metatarsal length after osteotomy was 6+/-6 mm. The single oblique lesser metatarsal osteotomy may be successful, but one half of the patients continued to have some degree of pain and most patients had limitations in footwear. Overall results were disappointing, and patients who are offered this procedure should be advised of its limitations.

Cast metal, resin-bonded prostheses: a 10-year retrospective study.

PubMed

Williams, V D; Thayer, K E; Denehy, G E; Boyer, D B

1989-04-01

A sample of 99 resin-bonded prostheses placed over a 10-year period were examined by four clinicians using a standardized criteria sheet. Areas examined included hard tissues, periodontium, retainer and pontic design, retention, the effect of occlusion on framework design and retention rate, and bonding media. The data from 7- and 10-year retrospective studies were compared for meaningful trends. Results showed (1) caries on retainer teeth was 3%, (2) gingival index of the retainer teeth was less than the gingival index of the rest of the mouth (0.7 +/- 0.5 versus 0.9 +/- 0.6), (3) the respective mean probing depths of retainer teeth of 34 patients in the 7- and 10-year studies were 2.2 +/- 0.4 mm and 1.9 +/- 0.7 mm, (4) the debond rate of all the prostheses from all causes was 31%, (5) the debond rate comparing etched metal and perforated retainers from all causes was 32% and 31% [corrected], respectively, and (6) 83% liked the prosthesis; 17% were noncommittal. The authors concluded that the resin-bonded prosthesis may be considered a permanent restoration and a valuable asset in the clinician's armamentarium.

Weight-loss maintenance for 10 years in the National Weight Control Registry.

PubMed

Thomas, J Graham; Bond, Dale S; Phelan, Suzanne; Hill, James O; Wing, Rena R

2014-01-01

The challenge of weight-loss maintenance is well known, but few studies have followed successful weight losers over an extended period or evaluated the effect of behavior change on weight trajectories. To study the weight-loss trajectories of successful weight losers in the National Weight Control Registry (NWCR) over a 10-year period, and to evaluate the effect of behavior change on weight-loss trajectories. A 10-year observational study of self-reported weight loss and behavior change in 2886 participants (78% female; mean age 48 years) in the NWCR who at entry had lost at least 30 lbs (13.6 kg) and kept it off for at least one year. Data were collected in 1993-2010; analysis was conducted in 2012. Weight loss (kilograms; percent weight loss from maximum weight). Mean weight loss was 31.3 kg (95% CI=30.8, 31.9) at baseline, 23.8 kg (95% CI=23.2, 24.4) at 5 years and 23.1±0.4 kg (95% CI=22.3, 23.9) at 10 years. More than 87% of participants were estimated to be still maintaining at least a 10% weight loss at Years 5 and 10. Larger initial weight losses and longer duration of maintenance were associated with better long-term outcomes. Decreases in leisure-time physical activity, dietary restraint, and frequency of self-weighing and increases in percentage of energy intake from fat and disinhibition were associated with greater weight regain. The majority of weight lost by NWCR members is maintained over 10 years. Long-term weight-loss maintenance is possible and requires sustained behavior change. © 2013 American Journal of Preventive Medicine Published by American Journal of Preventive Medicine All rights reserved.

CUORE project: implementation of the 10-year risk score.

PubMed

Palmieri, Luigi; Rielli, Rita; Demattè, Luca; Donfrancesco, Chiara; Ciccarelli, Paola; De Sanctis Caiola, Patrizia; Dima, Francesco; Lo Noce, Cinzia; Brignoli, Ovidio; Cuffari, Alfredo; Giampaoli, Simona

2011-08-01

The Italian national prevention plan 2005-2008 included 10-year cardiovascular risk (10-CR) assessment of the general population aged 35-69 years using the CUORE project risk score. General practitioners (GPs) were encouraged to collect data on risk factors and 10-CR and to contribute to the Cardiovascular Risk Observatory (CRO). The aim is to demonstrate feasibility and effectiveness of 10-CR assessment as a first step to implement primary preventive actions at the individual level. Data were collected using CUORE.EXE software, easily and freely downloadable by GPs from the CUORE project website (www.cuore.iss.it). CRO provides a web platform to analyse and compare data on 10-CR and risk factors at regional and national levels with the aim of supporting health policy decision processes. From January 2007 to May 2010, 2,858 GPs downloaded cuore.exe; 139,269 CR assessments on 117,345 persons were sent to CRO. CR mean was 3.0% in women, 8.3% in men; 30% of men and 65% of women were at lower risk (CR < 3%), 9.2% of men and 0.4% of women were at high risk (CR ≥ 20%). Among those with at least two risk assessments (n = 5,948), 8% (95% CI 7-9%) shifted to a lower risk class after 1 year. Systolic blood pressure mean levels decreased by 1.6 mmHg (95% CI 1.2-2.1 mmHg), diastolic blood pressure by 0.9 mmHg (95% CI 0.5-1.3 mmHg), total cholesterol by 5.6 mg/dl (95% CI 4.3-6.8 mg/dl), and smokers prevalence by 3.5% (95% CI 2.5-4.6%); high-density lipoprotein cholesterol increased in women by 1 mg/dl (95% CI 0.5-1.4 mg/dl). Data demonstrate that 10-CR assessment can be the first step to implement preventive actions in primary care.

The past 10 years of gastroenterology and hepatology-reflections and predictions.

PubMed

Friedman, Scott L; Quigley, Eamonn M M; Sharkey, Keith A; Sung, Joseph J Y; Whitcomb, David C

2014-11-01

In November 2004, the very first issue of this journal featured articles on the pathogenesis of ulcerative colitis, mechanisms leading to chronic pancreatitis, and treatment of recurrent Clostridium-difficile-associated diarrhoea. Although those topics might seem familiar, much has changed in the intervening years in our understanding, diagnosis and treatment of many different diseases across the field of gastroenterology and hepatology. Nonetheless, many challenges remain. Here, we have asked five of our Advisory Board members-international experts across different subspecialties in gastroenterology and hepatology-to reflect on the progress and frustrations of the past 10 years. They also comment on where effort and money should be invested now, as well as their predictions for progress in the next 10 years.

Dental age estimation: the role of probability estimates at the 10 year threshold.

PubMed

Lucas, Victoria S; McDonald, Fraser; Neil, Monica; Roberts, Graham

2014-08-01

The use of probability at the 18 year threshold has simplified the reporting of dental age estimates for emerging adults. The availability of simple to use widely available software has enabled the development of the probability threshold for individual teeth in growing children. Tooth development stage data from a previous study at the 10 year threshold were reused to estimate the probability of developing teeth being above or below the 10 year thresh-hold using the NORMDIST Function in Microsoft Excel. The probabilities within an individual subject are averaged to give a single probability that a subject is above or below 10 years old. To test the validity of this approach dental panoramic radiographs of 50 female and 50 male children within 2 years of the chronological age were assessed with the chronological age masked. Once the whole validation set of 100 radiographs had been assessed the masking was removed and the chronological age and dental age compared. The dental age was compared with chronological age to determine whether the dental age correctly or incorrectly identified a validation subject as above or below the 10 year threshold. The probability estimates correctly identified children as above or below on 94% of occasions. Only 2% of the validation group with a chronological age of less than 10 years were assigned to the over 10 year group. This study indicates the very high accuracy of assignment at the 10 year threshold. Further work at other legally important age thresholds is needed to explore the value of this approach to the technique of age estimation. Copyright © 2014. Published by Elsevier Ltd.

Can concomitant-boost accelerated radiotherapy be adopted as routine treatment for head-and-neck cancers? A 10-year single-institution experience.

PubMed

Allal, Abdelkarim S; Taussky, Daniel; Mach, Nicolas; Becker, Minerva; Bieri, Sabine; Dulguerov, Pavel

2004-04-01

Accelerated schedules are effective in overcoming repopulation during radiotherapy (RT) for head-and-neck cancers, but their feasibility is compromised by increased toxicity. The therapeutic ratio may be particularly favorable for 5-week regimens. This study reports the 10-year experience of a single institution in the routine use of concomitant boost RT as standard radical treatment in all but the most favorable stage patients. Between February 1991 and June 2001, 296 patients (mean age, 59 years) were treated with concomitant boost RT either alone (67%) or combined with cisplatin-based chemotherapy (33%), with a median tumor dose of 69.9 Gy. Tumors were located in the oropharynx in 52%, hypopharynx in 20%, larynx in 15%, nasopharynx in 7%, and oral cavity in 6%. International Union Against Cancer Stage III-IV disease represented 77% of tumors. The median follow-up for surviving patients was 55 months (range, 10-138 months). The RT schedule was completed to the prescribed dose in all but 1 patient. Twenty patients (7%) had a treatment interruption (median, 5 days; range, 2-35 days). Grade 3-4 Radiation Therapy Oncology Group acute toxicity was observed in 77% of patients, and nutritional support was required in 110 patients (37%). For all patients, the 5-year actuarial locoregional control and disease-free survival rate was 72% and 61%, respectively. In a multivariate analysis, only T and N stage was significantly associated with locoregional control and disease-free survival. Grade 3-4 late toxicity occurred in 14%, mostly bone and cartilage necrosis. The present, moderately accelerated, concomitant boost regimen is logistically feasible, causing minimal inconvenience to the technical staff and yielding a high rate of patient compliance. Concomitant chemotherapy administration is feasible provided that patients are carefully selected and supportive care is introduced in a timely fashion. Considering the manageable toxicity and the satisfactory tumor control

Comparison of MODIS and VIIRS Snow Cover Products for the 2016 Hydrological Year

NASA Astrophysics Data System (ADS)

Klein, A. G.; Thapa, S.

2017-12-01

The VIIRS (Visible Infrared Imaging Radiometer Suite) instrument on board the Suomi-NPP satellite aims to provide long-term continuity of several environmental data series including snow cover initiated with MODIS. While it is speculated that MODIS and VIIRS snow cover products may differ because of their differing spatial resolutions and spectral coverage quantitative comparisons between their snow products are currently limited. Therefore this study intercompares MODIS and VIIRS snow products for the 2016 Hydrological Year over the Midwestern United States and southern Canada. Two hundred and forty-four swath snow products from MODIS/Aqua (MYD10L2) and the VIIRS EDR (VSCMO/binary) were intercompared using confusion matrices, comparison maps and false color imagery. Thresholding the MODIS NDSI Snow Cover product at a snow cover fraction of 30% generated binary snow maps most comparable to the NOAA VIIRS binary snow product. Overall agreement between MODIS and VIIRS was found to be approximately 98%. This exceeds the VIIRS accuracy requirements of 90% probability of correct typing. Agreement was highest during the winter but lower during late fall and spring. Comparability was lowest over forest. MODIS and VIIRS often mapped snow/no-snow transition zones as cloud. The assessment of total snow and cloud pixels and comparison snow maps of MODIS and VIIRS indicates that VIIRS is mapping more snow cover and less cloud cover compared to MODIS. This is evidenced by the average area of snow in MYD10L2 and VSCMO being 5.72% and 11.43%, no-snow 26.65% and 28.67%, and cloud 65.02% and 59.91%, respectively. Visual comparisons depict good qualitative agreement between snow cover area visible in MODIS and VIIRS false color imagery and mapped in their respective snow cover products. While VIIRS and MODIS have similar capacity to map snow cover, VIIRS has the potential to more accurately map snow cover area for the successive development of climate data records.

Can Good Infection Control Be Obtained in One-stage Exchange of the Infected TKA to a Rotating Hinge Design? 10-year Results.

PubMed

Zahar, Akos; Kendoff, Daniel O; Klatte, Till O; Gehrke, Thorsten A

2016-01-01

Prosthetic joint infection (PJI) occurs in 1% to 2% of total knee arthroplasties (TKAs). Although two-stage exchange is the preferred management method of patients with chronic PJI in TKA in North America, one-stage exchange is an alternative treatment method, but long-term studies of this approach have not been conducted. We reviewed our minimum 9-year results of 70 patients who underwent one-stage exchange arthroplasty with a rotating hinge design to determine: (1) What was the proportion of patients free of infection? (2) What was the patient rate of survival free of any reoperation? (3) What were the clinical outcomes as measured by Hospital for Special Surgery scores? (4) What proportion of patients developed radiographic evidence of loosening? All one-stage revision TKAs for infection between January 1 and December 31, 2002, with a minimum 9-year followup (mean, 10 years; range, 9-11 years), in which patients had been seen within the last 1 year, were included in this retrospective review. During that period, 11 patients with infected TKAs were treated with other approaches (including two-stage approaches in eight); the general indication for one-stage revision was the diagnosis of PJI with a known causative organism. Exclusion criteria were culture-negative preoperative aspiration, known allergy to local antibiotics or bone cement, or cases in which radical débridement was impossible as a result of the involvement of important anatomical structures. Eighty-one patients with PJI were seen during this period; 70 underwent one-stage exchange using our strict protocol and were reimplanted with a rotating hinge TKA. Eleven patients (15.7%) were lost to followup. Hospital for Special Surgery scores were recorded and all radiographs were evaluated for prosthetic loosening. Failure was defined as revision surgery for infection or any other cause. Our 10-year infection-free survival was 93% (mean, 4.1; 95% confidence interval [CI], 89%-96%; p < 0.007); and the

A bibliometric analysis of toxicology research productivity in Middle Eastern Arab countries during a 10-year period (2003–2012)

PubMed Central

2014-01-01

Background Bibliometric studies are increasingly being used for research assessment by involving the application of statistical methods to scientific publications to obtain the bibliographics for each country. The main objective of this study was to analyse the research productivity originating from 13 Middle Eastern Arab (MEA) countries with articles published in toxicology journals. Methods Data from January 1, 2003 till December 31, 2012 were searched for documents with specific words in the toxicology field as a “source title” in any one of the 13 MEA countries. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies. Research productivity was adjusted to the national population and nominal gross domestic product (GDP) per capita. Results Documents (n = 1,240) were retrieved from 73 international peer-reviewed toxicology journals. The h-index of the retrieved documents was 39. Of the 73 journal titles, 52 (69.9%) have their IF listed in the ISI Journal Citation Reports 2012; 198 documents (16.0%) were published in journals that had no official IF. After adjusting for economy and population power, Egypt (193.6), Palestine (18.1), Kingdom of Saudi Arabia (KSA) (13.0), and Jordan (11.5) had the highest research productivity. Countries with large economies, such as the Kuwait, United Arab Emirates (UAE), and Oman, tended to rank relatively low after adjustment of GDP. The total number of citations at the time of data analysis (August 4, 2013) was 10,991, with a median (interquartile range) of 4 (1–11). MEA collaborated more with countries in the MEA regions (16.7%), especially KSA, Egypt, and UAE, followed by Europe (14.4%), especially with the United Kingdom and Germany. Conclusions The present data show a promising rise and a good start for toxicology research activity in toxicology journals in the Arab world. Research output is low in some countries, which can be improved by investing in more

[Epidemiologic outbreak of Legionnaire's disease in an open community: 10 years later].

PubMed

Císcar, M A; Barranco, M J; Peris, R; Ramón, M; Juan, G

1994-01-01

The aim of this study was to describe an outbreak of pneumonia due to L. pneumophila in Llutxent (Valencia) and to know the evolution of these patients 10 years after. The definition and identification of cases was carried out with the use of IFI techniques. An environmental and epidemiological study was performed for determining the origin and route of disease dissemination. The patients were clinically, functionally and serologically reviewed 10 years after. From July to August 1983, 35 cases of pneumonia were reported in Llutxent (rate = 1.5%). L. pneumophila serotype 1 was serologically identified and was also found in shower heads and toilet tanks (in the context of the entry of sand into the drinking water supply). Ten years after, the patients had no respiratory symptoms with titers of antibodies versus Legionella sp. being under 1/64. The authors emphasize the involvement of the distribution system for drinking water to the population in this first outbreak of Legionnaires disease in an open community. The health care measures taken were effective as demonstrated by no further pneumonias being recorded and after normalization of the rate of antibodies on a 10 year review.

Haiti's progress in achieving its 10-year plan to eliminate cholera: hidden sickness cannot be cured.

PubMed

Koski-Karell, Victoria; Farmer, Paul E; Isaac, Benito; Campa, Elizabeth M; Viaud, Loune; Namphy, Paul C; Ternier, Ralph; Ivers, Louise C

2016-01-01

Since the beginning of the cholera epidemic in Haiti 5 years ago, the prevalence of this deadly water-borne disease has fallen far below the initial rates registered during its explosive outset. However, cholera continues to cause extensive suffering and needless deaths across the country, particularly among the poor. The urgent need to eliminate transmission of cholera persists: compared to the same period in 2014, the first 4 months of 2015 saw three times the number of cholera cases. Drawing upon epidemiology, clinical work (and clinical knowledge), policy, ecology, and political economy, and informed by ethnographic data collected in a rural area of Haiti called Bocozel, this paper evaluates the progress of the nation's 10-year Plan for the Elimination of Cholera. Bocozel is a rice-producing region where most people live in extreme poverty. The irrigation network is decrepit, the land is prone to environmental shocks, fertilizer is not affordable, and the government's capacity to assist farmers is undermined by resource constraints. When peasants do have rice to sell, the price of domestically grown rice is twice that of US-imported rice. Canal water is not only used to irrigate thousands of acres of rice paddies and sustain livestock, but also to bathe, wash, and play, while water from wells, hand pumps, and the river is used for drinking, cooking, and bathing. Only one out of the three government-sponsored water treatment stations in the research area is still functional and utilized by those who can afford it. Latrines are scarce and often shared by up to 30 people; open defecation remains common. Structural vulnerabilities cut across all sectors - not just water, sanitation, health care, and education, but agriculture, environment, (global and local) commerce, transportation, and governance as well. These are among the hidden sicknesses that impede Haiti and its partners' capacity to eliminate cholera.

Evaluation of fire-safety programs that use 10-year smoke alarms.

PubMed

Jackson, Mark; Wilson, Jonathan; Akoto, Judith; Dixon, Sherry; Jacobs, David E; Ballesteros, Michael F

2010-10-01

The Centers for Disease Control and Prevention began funding a Smoke Alarm Installation and Fire Safety Education (SAIFE) program in 1998. This program involves the installation of lithium-powered "10-year" smoke alarms in homes at high risk for fires and injuries. This study aimed to (1) determine among original SAIFE homes if the lithium-powered alarms were still present and functional 8-10 years after installation and (2) understand factors related to smoke alarm presence and functionality. Data on a total of 384 homes and 601 smoke alarms in five states were collected and analyzed. Only one-third of alarms were still functional; 37% of installed alarms were missing; and 30% of alarms were present, but not functioning. Alarms were less likely to be functioning if they were installed in the kitchen and if homes had a different resident at follow-up. Of the 351 alarms that were present and had a battery at the time of the evaluation, only 21% contained lithium-powered batteries. Of these, 78% were still functioning. Programs that install lithium-powered alarms should use units that have sealed-in batteries and "hush" buttons. Additionally, education should be given on smoke alarm maintenance that includes a message that batteries in these alarms should not be replaced. Lithium-powered smoke alarms should last up to 10 years if maintained properly.

40 CFR 415.10 - Applicability; description of the aluminum chloride production subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... aluminum chloride production subcategory. 415.10 Section 415.10 Protection of Environment ENVIRONMENTAL... SOURCE CATEGORY Aluminum Chloride Production Subcategory § 415.10 Applicability; description of the aluminum chloride production subcategory. The provisions of this subpart are applicable to discharges and...

Production Program - Operational - SNAP 10A Units

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1961-08-07

This planning report is provided to describe the lead time, approximate costs, and major decisions and approvals required to enter a production program for the 500 watt SNAP 10A nuclear space power system.

7 CFR 1219.10 - Fiscal period or marketing year.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Fiscal period or marketing year. 1219.10 Section 1219.10 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass...

Cosmogenic 10Be signature of geomagnetic dipole moment variations over the last 2 Ma

NASA Astrophysics Data System (ADS)

Simon, Q.; Thouveny, N.; Bourlès, D. L.; Valet, J. P.; Bassinot, F. C.; Savranskaia, T.; Duvivier, A.; Choy, S.; Gacem, L.; Villedieu, A.

2017-12-01

Long-term variations of the geomagnetic dipole moment (GDM) during periods of stable polarity and in transitional states (reversals and excursions) provide key information for understanding the geodynamo regime. Authigenic 10Be/9Be ratios (Be-ratio, proxy of atmospheric 10Be production) from marine sedimentary cores give independent and additional insights on the evolution of the geomagnetic intensity, completing information from absolute and relative paleointensity (RPI) records. Here we present new Be-ratio results obtained on several marine cores from the North Atlantic, Indian and Pacific Oceans which permit to extent into the Matuyama chron our previous 10Be-derived GDM reconstructions (Simon et al., 2016 JGR 121). Stratigraphic offsets measured between Be-ratio peaks and the corresponding RPI minima in each studied cores are assigned to (post-) detrital remanent magnetization (pDRM) effects leading to magnetization locking-in delays varying from 0 to 16 cm (up to 12 ka). All these results were compiled in order to obtain a continuous Be-ratio record covering the last 2 Ma. 10Be overproduction episodes triggered by geomagnetic dipole moment lows (GDL) linked to polarity reversals and excursions confirm the global control exerted by the GDM on cosmogenic radionuclides production. A dipole moment reconstruction derived from the Be-ratio stack (BeDiMo2Ma) was calibrated using absolute paleointensity data. This independent record completes the available paleomagnetic RPI records and permits: 1) to confront and increase the robustness and precision of GDM reconstructions; and, 2) to better constrain geomagnetic field instabilities during the mid- to late- Matuyama chron. Our new 10Be derived inventory is fully compatible with the GDL series linked to polarity reversals (Matuyama-Brunhes transition, Jaramillo and Olduvai boundaries), geomagnetic events (Cobb Mountain, Réunion) and Brunhes' excursions (e.g. Laschamp, Blake, Iceland-Basin, Big Lost). It further

Predictors of subjective health status 10 years post-PCI.

PubMed

van den Berge, Jan C; Dulfer, Karolijn; Utens, Elisabeth M W J; Hartman, Eline M J; Daemen, Joost; van Geuns, Robert J; van Domburg, Ron T

2016-06-01

Subjective health status is an increasingly important parameter to assess the effect of percutaneous coronary intervention (PCI) in clinical practice. Aim of this study was to determine medical and psychosocial predictors of poor subjective health status over a 10 years' post-PCI period. We included a series of consecutive PCI patients (n = 573) as part of the RESEARCH registry, a Dutch single-center retrospective cohort study. These patients completed the 36-item Short-Form Health Survey (SF-36) at baseline and 10 years post-PCI. We found 6 predictors of poor subjective health status 10 years post-PCI: SF-36 at baseline, age, previous PCI, obesity, acute myocardial infarction as indication for PCI, and diabetes mellitus (arranged from most to least numbers of sub domains). SF-36 scores at baseline, age, and previous PCI were significant predictors of subjective health status 10 years post-PCI. Specifically, the SF-36 score at baseline was an important predictor. Thus assessment of subjective health status at baseline is useful as an indicator to predict long-term subjective health status. Subjective health status becomes better by optimal medical treatment, cardiac rehabilitation and psychosocial support. This is the first study determining predictors of subjective health status 10 years post-PCI.

Delayed vaginal and urethral mesh exposure: 10 years after TVT surgery.

PubMed

Khanuengkitkong, Siwatchaya; Lo, Tsia-Shu; Dass, Anil Krishna

2013-03-01

Delayed mesh exposure after tension-free vaginal tape (TVT) procedure is rare. We report a case of mesh exposure into the vagina and urethra that developed 10 years after TVT surgery. A 58-year-old postmenopausal woman presented with mixed urinary incontinence. She was investigated, and her stress urinary incontinence was cured with a TVT procedure 10 years ago. She was then scheduled follow-up annually. Two years postsurgery, a granulation tissue was observed and excised at the vaginal incision site. Vaginal examination 10 years postsurgery showed vaginal mesh erosion 0.5 cm from urethral meatus. Cystoscopy revealed concomitant urethral erosion at the posterior urethral wall. Mesh excision was performed, and urethra and vagina were repaired in layers. Postoperative recovery was uneventful. This finding shows that, although rare, complications can occur even after 10 years of TVT surgery.

The CREp program, a fully parameterizable program to compute exposure ages (3He, 10Be)

NASA Astrophysics Data System (ADS)

Martin, L.; Blard, P. H.; Lave, J.; Delunel, R.; Balco, G.

2015-12-01

Over the last decades, cosmogenic exposure dating permitted major advances in Earth surface sciences, and particularly in paleoclimatology. Yet, exposure age calculation is a dense procedure. It requires numerous choices of parameterization and the use of an appropriate production rate. Nowadays, Earth surface scientists may either calculate exposure ages on their own or use the available programs. However, these programs do not offer the possibility to include all the most recent advances in Cosmic Ray Exposure (CRE) dating. Notably, they do not propose the most recent production rate datasets and they only offer few possibilities to test the impact of the atmosphere model and the geomagnetic model on the computed ages. We present the CREp program, a Matlab © code that computes CRE ages for 3He and 10Be over the last 2 million years. The CREp program includes the scaling models of Lal-Stone in the "Lal modified" version (Balco et al., 2008; Lal, 1991; Stone, 2000) and the LSD model (Lifton et al., 2014). For any of these models, CREP allows choosing between the ERA-40 atmosphere model (Uppala et al., 2005) and the standard atmosphere (National Oceanic and Atmospheric Administration, 1976). Regarding the geomagnetic database, users can opt for one of the three proposed datasets: Muscheler et al. 2005, GLOPIS-75 (Laj et al. 2004) and the geomagnetic framework proposed in the LSD model (Lifton et al., 2014). They may also import their own geomagnetic database. Importantly, the reference production rate can be chosen among a large variety of possibilities. We made an effort to propose a wide and homogenous calibration database in order to promote the use of local calibration rates: CREp includes all the calibration data published until July 2015 and will be able to access an updated online database including all the newly published production rates. This is crucial for improving the ages accuracy. Users may also choose a global production rate or use their own data

9 CFR 145.10 - Terminology and classification; flocks, products, and States.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Terminology and classification; flocks, products, and States. 145.10 Section 145.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE LIVESTOCK IMPROVEMENT NATIONAL POULTRY IMPROVEMENT PLAN FOR BREEDING...

9 CFR 145.10 - Terminology and classification; flocks, products, and States.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Terminology and classification; flocks, products, and States. 145.10 Section 145.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE LIVESTOCK IMPROVEMENT NATIONAL POULTRY IMPROVEMENT PLAN FOR BREEDING...

Laparoscopic Heller myotomy for achalasia: results after 10 years.

PubMed

Cowgill, Sarah M; Villadolid, Desiree; Boyle, Robert; Al-Saadi, Sam; Ross, Sharona; Rosemurgy, Alexander S

2009-12-01

Laparoscopic Heller myotomy was first undertaken in the early 1990s, and appreciable numbers of patients with 10-year follow-up periods are now available. This study was undertaken to determine long-term outcomes after laparoscopic Heller myotomy used to treat achalasia. Of 337 patients who have undergone laparoscopic Heller myotomy since 1992, 47 who underwent myotomy more than 10 years ago have been followed through a prospectively maintained registry. Among many symptoms, patients scored dysphagia, chest pain, vomiting, regurgitation, choking, and heartburn before and after myotomy using a Likert scale with choices ranging from 0 (never/not bothersome) to 10 (always/very bothersome). Symptom scores before and after myotomy were compared using a Wilcoxon matched-pairs test. Data are reported as median (mean ± standard deviation). The median length of the hospital stay was 2 days (mean, 3 ± 8.6 days; range, 1-60 days). Notable complications were infrequent after myotomy. There were no perioperative deaths. One patient required a redo myotomy after 5 years due to recurrence of symptoms. At this writing, 33 patients (70%) are still alive. The causes of death after discharge were unrelated to myotomy. The frequency and severity scores for dysphagia, chest pain, vomiting, regurgitation, choking, and heartburn all decreased significantly after laparoscopic Heller myotomy (p < 0.0001 for all). Laparoscopic Heller myotomy can be undertaken with few complications. This procedure significantly decreases the frequency and severity of achalasia symptoms without promoting heartburn. The symptoms of achalasia are durably ameliorated by laparoscopic Heller myotomy during long-term follow-up evaluation, thereby promoting application of this procedure.

Production of interleukin-10 by human bronchogenic carcinoma.

PubMed Central

Smith, D. R.; Kunkel, S. L.; Burdick, M. D.; Wilke, C. A.; Orringer, M. B.; Whyte, R. I.; Strieter, R. M.

1994-01-01

Interleukin-10 (IL-10) is a recently characterized cytokine with suppressive activity against various aspects of the cellular immune response. Our laboratory has previously demonstrated that another anti-inflammatory cytokine, IL-1 receptor antagonist (IRAP) is produced and secreted by human bronchogenic carcinomas. We speculated that tumor production of IRAP may mitigate host responses and confer increased tumor viability. In this study, we investigated the capacity of human bronchogenic tumors to produce IL-10 as another possible mechanism to attenuate host defenses. We found increased levels of antigenic IL-10 in tissue homogenates of human bronchogenic carcinomas compared with normal lung tissue (13.69 +/- 2.87 versus 5.84 +/- 0.84 ng/mg total protein). Immunohistochemical staining of tumors illustrate primary localization of antigenic IL-10 to individual tumor cells. Analysis of supernatants of several unstimulated human bronchogenic cell lines in vitro demonstrated the ability of tumor cells to constitutively produce IL-10. Functional studies of mononuclear cells, cultured in the presence of conditioned medium from a bronchogenic cell line, demonstrated their increased tumor necrosis factor and IL-6 production with the addition of neutralizing antibodies to IL-10. These findings demonstrate that human bronchogenic carcinomas elaborate functional IL-10, which may significantly impair immune effector cell function and enable the tumor to evade host defenses. Images Figure 1 Figure 2 PMID:8030748

Nonfatal Assaults Among Persons Aged 10-24 Years - United States, 2001-2015.

PubMed

David-Ferdon, Corinne F; Haileyesus, Tadesse; Liu, Yang; Simon, Thomas R; Kresnow, Marcie-Jo

2018-02-09

In 2015, persons aged 10-24 years who were treated for nonfatal assault injuries in emergency departments (EDs) in the United States accounted for 32% of the approximately 1.5 million patients of all ages that EDs treated for nonfatal assault injuries (1). CDC analyzed data from the National Electronic Injury Surveillance System-All Injury Program (NEISS-AIP) to examine 2001-2015 trends in nonfatal assault injuries among youths treated in EDs, by sex and age group, and to assess current rates by sex, age group, mechanism of injury, and disposition (1). Rates for 2001-2015 were significantly higher among males than among females and among young adults aged 20-24 years than among youths aged 10-14 and 15-19 years. During 2011-2015, rates declined for all groups. The 2015 rate among persons aged 10-24 years was 753.2 per 100,000 population, the lowest in the 15-year study period. Despite encouraging trends, the assault rate among young persons remains high. Rates in 2015 were higher among males, persons aged 20-24 years, and those who incurred intentional strike or hit injuries. Nearly one in 10 patients were admitted to the hospital, transferred to another hospital, or held for observation. Youth violence prevention strategies, including primary prevention approaches that build individual skills, strengthen family relationships, or connect young persons treated in EDs to immediate and ongoing support, can be implemented to decrease injuries and fatalities (2).

After 10 years of service, NOAA retires GOES-12 satellite

Science.gov Websites

Destinations After 10 years of service, NOAA retires GOES-12 satellite Progress continuing toward launch of next-generation GOES-R satellite August 19, 2013 GOES-12 captured this visible image of Hurricane 10 years of stellar service, NOAA's Geostationary Operational Environmental Satellite (GOES)-12

Antipsychotic medication and remission of psychotic symptoms 10years after a first-episode psychosis.

PubMed

Wils, Regitze Sølling; Gotfredsen, Ditte Resendal; Hjorthøj, Carsten; Austin, Stephen F; Albert, Nikolai; Secher, Rikke Gry; Thorup, Anne Amalie Elgaard; Mors, Ole; Nordentoft, Merete

2017-04-01

Several national guidelines recommend continuous use of antipsychotic medication after a psychotic episode in order to minimize the risk of relapse. However some studies have identified a subgroup of patients who obtain remission of psychotic symptoms while not being on antipsychotic medication for a period of time. This study investigated the long-term outcome and characteristics of patients in remission of psychotic symptoms with no use of antipsychotic medication at the 10-year follow-up. The study was a cohort study including 496 patients diagnosed with schizophrenia spectrum disorders (ICD 10: F20 and F22-29). Patients were included in the Danish OPUS Trial and followed up 10years after inclusion, where patient data was collected on socio-demographic factors, psychopathology, level of functioning and medication. 61% of the patients from the original cohort attended the 10-year follow up and 30% of these had remission of psychotic symptoms at the time of the 10-year follow up with no current use of antipsychotic medication. This outcome was associated with female gender, high GAF-F score, participation in the labour market and absence of substance abuse. Our results describe a subgroup of patients who obtained remission while not being on antipsychotic medication at the 10-year follow-up. The finding calls for further investigation on a more individualized approach to long-term treatment with antipsychotic medication. Copyright © 2016 Elsevier B.V. All rights reserved.

7 CFR 625.9 - 10-year restoration cost-share agreements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false 10-year restoration cost-share agreements. 625.9... CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE WATER RESOURCES HEALTHY FORESTS RESERVE PROGRAM § 625.9 10-year restoration cost-share agreements. (a) The restoration plan developed under § 625.12 forms the basis for the...

Shift in sodium chloride sources in past 10 years of salt reduction campaign in Japan.

PubMed

Shimbo, S; Hatai, I; Saito, T; Yokota, M; Imai, Y; Watanabe, T; Moon, C S; Zhang, Z W; Ikeda, M

1996-11-01

Twenty four-hr total food duplicate samples were collected from nonsmoking house-wives (aged mostly 30 to 60 years) twice at a 10-year interval in winter seasons, once in around 1980 and then in around 1990 in 11 prefectures in Japan. In practice, 342 and 472 samples were obtained in the 1980 and 1990 studies, respectively. Sodium chloride (NaCl) intake via each food item was estimated from the weight of the item in the duplicate. The comparison of 1990 results with 1980 results showed that the total NaCl intake (i.e., NaCl intake via all food items) decreased after a 10-year campaign to lower salt intake. The NaCl/energy ratio however stayed essentially unchanged. Whereas NaCl intake via pickles decreased remarkably and that via miso paste [a fermentation product of soy bean, rice (or wheat) and salt] slightly, the decreases were counteracted by a substantial increase in NaCl intake via soy bean sauce. Meaning of this unexpected counteraction was discussed in relation to the difficulties in the campaign to lower salt intake.

IL-29 Enhances CXCL10 Production in TNF-α-stimulated Human Oral Epithelial Cells.

PubMed

Hosokawa, Yoshitaka; Hosokawa, Ikuko; Shindo, Satoru; Ozaki, Kazumi; Matsuo, Takashi

2017-08-01

Interleukin-29 (IL-29) is a cytokine belonging to the Type III interferon family. It was recently detected in the gingival crevicular fluid of periodontitis patients. However, the role of IL-29 in the pathogenesis of periodontal disease remains unknown. The aim of this study was to examine the effects of IL-29 on C-X-C motif chemokine ligand 10 (CXCL10) production in human oral epithelial cells. We measured CXCL10 production in TR146 cells, which is a human oral epithelial cell line, using an enzyme-linked immunosorbent assay. We used a Western blot analysis to detect IL-29 receptor expression and the phosphorylation levels of signal transduction molecules, including p38 mitogen-activated protein kinases (MAPK), signal transducer and activator of transcription 3 (STAT3), and nuclear factor (NF)- κB p65, in the TR146 cells. The TR146 cells expressed the IL-29 receptor. IL-29 induced CXCL10 production in the TR146 cells. IL-29 significantly enhanced CXCL10 production in tumor necrosis factor (TNF)-α-stimulated TR146 cells. The p38 MAPK, STAT3, and NF-κB pathways were found to be related to the IL-29-induced enhancement of CXCL10 production in TNF-α-stimulated TR146 cells. IL-29 promotes T helper 1-cell accumulation in periodontal lesions by inducing CXCL10 production in oral epithelial cells.

Five- and 10-Year Follow-Up of Nonvascularized Toe Phalanx Transfers.

PubMed

Kawabata, Hidehiko; Tamura, Daisuke

2018-05-01

The purpose of this study was to evaluate long-term outcomes of nonvascularized toe phalanx transfer. We retrospectively reviewed 54 nonvascularized toe phalanx transfers in 29 children with symbrachydactyly. Forty-seven transfers in 24 children were evaluated at 5-year follow-up and 27 transfers in 14 children were evaluated at 10-year follow-up. We recorded the incidence of the early physeal closure and the length of the transferred toe phalanx on plain radiographs at 5- and 10-year follow-up. Growth rate in the first 5 years and the following 5 years were calculated. Function of the metacarpophalangeal joint (motion, stability, and alignment) was also evaluated. The mean age at surgery was 1.5 years. Seven toe phalanges were trimmed because the skin pocket was tight. Five transfers required revision surgery for partial necrosis of the skin pocket. At 5-year follow-up, the physis was closed in 23%, and at 10 years, 78% of physes were closed. The phalanx length was 87% of expected at 5-year follow-up and 71% at 10-year follow-up. Growth rate was 0.83 mm/y in the first 5 years and 0.22 mm/y in the following 5 years. Active motion was rated as good in 24, fair in 7, and poor in 16. Stability and alignment were rated as good in 37 and 33, fair in 8 and 5, and poor in 2 and 9, respectively. Nonvascularized toe phalanx transfer offered a relatively simple method to lengthen short digits and to provide satisfactory function. The transferred toe phalanges grew at a near-normal rate in the first 5 years, but the growth rate decreased between 5 and 10 years. Therapeutic IV. Copyright © 2018 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

Nodular hidradenoma and hidradenocarcinoma. A 10-year review.

PubMed

Hernández-Pérez, E; Cestoni-Parducci, R

1985-01-01

We studied eighty-nine nodular hidradenomas (NHs) and six clear cell hidradenocarcinomas (CCHs) reported in a 10-year period. NHs were more commonly seen in women (ratio of 1.7 to 1); the average age was 37.2 years, and they were located mainly on the head. One CCH had widely disseminated metastasis that led to death. Other CCHs underwent spontaneous regression.

Productivity patterns in the equatorial Pacific over the last 30,000 years

NASA Astrophysics Data System (ADS)

Costa, Kassandra M.; Jacobel, Allison W.; McManus, Jerry F.; Anderson, Robert F.; Winckler, Gisela; Thiagarajan, Nivedita

2017-05-01

The equatorial Pacific traverses a number of productivity regimes, from the highly productive coastal upwelling along Peru to the near gyre-like productivity lows along the international dateline, making it an ideal target for investigating how biogeochemical systems respond to changing oceanographic conditions over time. However, conflicting reconstructions of productivity during periods of rapid climate change, like the last deglaciation, render the spatiotemporal response of equatorial Pacific productivity ambiguous. In this study, surface productivity since the last glacial period (30,000 years ago) is reconstructed from seven cores near the Line Islands, central equatorial Pacific, and integrated with productivity records from across the equatorial Pacific. Three coherent deglacial patterns in productivity are identified: (1) a monotonic glacial-Holocene increase in productivity, primarily along the Equator, associated with increasing nutrient concentrations over time; (2) a deglacial peak in productivity 15,000 years ago due to transient entrainment of nutrient rich southern-sourced deep waters; and (3) possible precessional cycles in productivity in the eastern equatorial Pacific that may be related to Intertropical Convergence Zone migration and potential interactions with El Niño-Southern Oscillation dynamics. These findings suggest that productivity was generally lower during the glacial period, a trend observed zonally across the equatorial Pacific, while deglacial peaks in productivity may be prominent only in the east.

High-level production of human interleukin-10 fusions in tobacco cell suspension cultures

PubMed Central

Kaldis, Angelo; Ahmad, Adil; Reid, Alexandra; McGarvey, Brian; Brandle, Jim; Ma, Shengwu; Jevnikar, Anthony; Kohalmi, Susanne E; Menassa, Rima

2013-01-01

The production of pharmaceutical proteins in plants has made much progress in recent years with the development of transient expression systems, transplastomic technology and humanizing glycosylation patterns in plants. However, the first therapeutic proteins approved for administration to humans and animals were made in plant cell suspensions for reasons of containment, rapid scale-up and lack of toxic contaminants. In this study, we have investigated the production of human interleukin-10 (IL-10) in tobacco BY-2 cell suspension and evaluated the effect of an elastin-like polypeptide tag (ELP) and a green fluorescent protein (GFP) tag on IL-10 accumulation. We report the highest accumulation levels of hIL-10 obtained with any stable plant expression system using the ELP fusion strategy. Although IL-10-ELP has cytokine activity, its activity is reduced compared to unfused IL-10, likely caused by interference of ELP with folding of IL-10. Green fluorescent protein has no effect on IL-10 accumulation, but examining the trafficking of IL-10-GFP over the cell culture cycle revealed fluorescence in the vacuole during the stationary phase of the culture growth cycle. Analysis of isolated vacuoles indicated that GFP alone is found in vacuoles, while the full-size fusion remains in the whole-cell extract. This indicates that GFP is cleaved off prior to its trafficking to the vacuole. On the other hand, IL-10-GFP-ELP remains mostly in the ER and accumulates to high levels. Protein bodies were observed at the end of the culture cycle and are thought to arise as a consequence of high levels of accumulation in the ER. PMID:23297698

Parental stress and perceived vulnerability at 5 and 10 years after pediatric SCT.

PubMed

Vrijmoet-Wiersma, C M J; Egeler, R M; Koopman, H M; Bresters, D; Norberg, A L; Grootenhuis, M A

2010-06-01

With the aim of assessing parental stress after SCT, 73 parents of children and adolescents who underwent SCT 5 or 10 years ago responded to questionnaires on general distress (General Health Questionnaire (GHQ)), disease-related stress (Pediatric Inventory for Parents-short form (PIP-SF)) and perceptions of child vulnerability (Child Vulnerability Scale (CVS)). General distress scores were comparable with the reference groups, but 40% of the mothers at 5 years after SCT reported increased stress levels as compared with 26% in the community-based reference group. Disease-related stress was comparable with the reference group of parents of children who were just off cancer treatment, 5 years after SCT. At 10 years after SCT, scores were lower than the reference group. Perceived child vulnerability did diminish over time, but remained high in parents of SCT survivors, compared with parents of healthy children: 96% of the parents at 5 years after SCT and 76% of the parents at 10 years after SCT scored above the cutoff point. Perceived vulnerability was found to be a predictor for parental disease-related stress. To conclude, although most parents of SCT survivors are resilient, the majority of parents perceive their child to be much more vulnerable as compared with parents of healthy children. This perception is associated with disease-related stress and may induce overprotective parenting.

Anterior Cervical Discectomy and Fusion Outcomes over 10 Years: A Prospective Study.

PubMed

Buttermann, Glenn R

2018-02-01

Prospective cohort study with >10-year follow-up. To assess the long-term, >10-year clinical outcomes of anterior cervical discectomy and fusion (ACDF) and to compare outcomes based on primary diagnosis of disc herniation, stenosis or advanced degenerative disc disease (DDD), number of levels treated, and preexisting adjacent level degeneration. ACDF is a proven treatment for patients with stenosis and disc herniation and results in significantly improved short- and intermediate-term outcomes. Motion preservation treatments may result in improved long-term outcomes but need to be compared to long-term ACDF outcomes reference. Patients who had disc herniation, stenosis, and DDD and underwent ACDF with or without decompression were prospectively enrolled and followed for a minimum of 10 years with outcome assessment at various intervals. All 159 consecutive patients had autogenous tricortical iliac crest bone graft and plate instrumentation used. Outcomes included visual analog scale for neck and arm pain. pain drawing, Oswestry Disability Index, and self-assessment of procedure success. Preoperative adjacent-level disc degeneration, pseudarthrosis, and secondary operations were analyzed. For all diagnostic groups, significant outcomes improvement was seen at all follow-up periods for all scales relative to preoperative scores. Outcomes were not related to age, gender, number of levels treated, and minimally to preexisting degeneration at the adjacent level. The use of narcotic pain medication decreased substantially. Neurological deficits almost all resolved. Patient self-reported success ranged from 85% to 95%. Over the long term, additional surgery for pseudarthrosis (10%) occurred in the early follow-up period, and for adjacent segment degeneration (21%), which occurred linearly during the >10-year follow-up period. ACDF leads to significantly improved outcomes for all primary diagnoses and was sustained for >10 years' follow-up. Secondary surgeries were

Neogene basin infilling from cosmogenic nuclides (10Be and 21Ne) in Atacama, Chile

NASA Astrophysics Data System (ADS)

Sanchez, Caroline; Regard, Vincent; Carretier, Sébastien; Riquelme, Rodrigo; Blard, Pierre-Henri; Campos, Eduardo; Brichau, Stéphanie; Lupker, Marteen; Hérail, Gérard

2017-04-01

In the hyperarid Atacama Desert, northern Chile, Neogene sediments host copper rich layers (exotic supergene mineralization). Current mines are excavated into relatively thin (<200-300 m) Neogene basins whose infilling chronology is poorly constrained. We took advantage of one of these mining pits, and sampled for 10Be and 21Ne cosmogenic nuclide dosing. These cosmogenic nuclides help constraining the infilling chronology. Indeed, basin sediments were deposited with a cosmogenic nuclide content acquired on hillslopes. Then within the basin, cosmogenic nuclide concentrations evolved through the competing production (quickly decreasing with depth) and disintegration (not for 21Ne). Sampling depths are at ˜100 m and at ˜50 m below the desert surface. First, 21Ne gives lower boundaries for upstream erosion rates or local sedimentation rate. These bounds are between 2 and 10 m/Ma, which is quite important for the area. The ratio between the two cosmogenic nuclides indicate a maximum burial age of 12 Ma (minimal erosion rate of 15 m/Ma) and is surprisingly similar from bottom to top, indicating a probable rapid infilling. We finally processed a Monte-Carlo inversion. This inversion helps taking into account the post-deposition muonic production of cosmogenic nuclides. Inversion results is dependent on the muonic production scheme. Interestingly, the similarity in concentrations from bottom to top pleads for quite low production at depth. Our data finally indicates a quick infilling between 12.5 and 10 Ma BP accounting for ˜100 m of deposition (minimum sedimentation rate of 40 m/Ma).

Predictors Associated with Changes of Weight and Total Cholesterol among two Occupational Cohorts over 10 Years

PubMed Central

Stanford, Joseph B.; Murtaugh, Maureen A.; Greenwood, Jessica L.J.; Gren, Lisa H.; Hegmann, Kurt T.; Thiese, Matthew S.

2015-01-01

Objective To ascertain worker health characteristics and psychosocial factors associated with changes in body weight and total cholesterol (TC) among two production operation populations. Methods We performed descriptive and predictive analysis of questionnaire data and biomedical measurements from two prospective cohort studies. Our key outcomes were changes in weight, and TC over 5–10 years between baseline and exit assessments. Results 146 subjects were analyzed. Increases in weight were associated with belief in being overweight and baseline overweight and obesity. Increases in TC levels were associated with female gender, belief that TC levels were “not good,” and feeling depressed. Conclusion Most of the reported associations with increases in weight and TC levels are amenable to interventions and may be a target for workplace intervention programs. PMID:26147542

Prospective Predictors of Body Dissatisfaction in Young Adults: 10-year Longitudinal Findings

PubMed Central

Quick, Virginia; Eisenberg, Marla E.; Bucchianeri, Michaela M.; Neumark-Sztainer, Dianne

2014-01-01

This study identified longitudinal risk factors for body dissatisfaction (BD) over a 10-year period from adolescence to young adulthood. Participants (N = 2134; age at baseline: M =15.0, SD =1.6 years) provided two waves of survey data. A 6-step hierarchical linear regression analysis examined the predictive contribution of Time 1 BD, weight status, demographics, family and peer environmental factors, and psychological factors. Among females, Asian race/ethnicity, low self-esteem, greater BD, and higher body mass index during adolescence contributed significantly to predicting greater BD at 10-year follow up (R2 = 0.27). Among males, demographics (i.e., Asian, other-mixed ethnicity, education attainment), depressive symptoms, greater BD, higher body mass index, more parent communication, and less peer weight teasing during adolescence contributed to BD at follow-up (R2 = 0.27). Findings indicate who may be at greatest risk for BD in young adulthood and the types of factors that should be addressed during adolescence. PMID:25045599

10Be in ice at high resolution: Solar activity and climate signals observed and GCM-modeled in Law Dome ice cores

NASA Astrophysics Data System (ADS)

Pedro, Joel; Heikkilä, Ulla; van Ommen, T. D.; Smith, A. M.

2010-05-01

Changes in solar activity modulate the galactic cosmic ray flux, and in turn, the production rate of 10Be in the earth's atmosphere. The best archives of past changes in 10Be production rate are the polar ice cores. Key challenges in interpreting these archives as proxies for past solar activity lie in separating the useful solar activity (or production) signal from the interfering meteorological (or climate) signal, and furthermore, in determining the atmospheric source regions of 10Be deposited to the ice core site. In this study we use a new monthly resolution composite 10Be record, which spans the past decade, and a general circulation model (ECHAM5-HAM), to constrain both the production and climate signals in 10Be concentrations at the Law Dome ice core site, East Antarctica. This study differs from most previous work on 10Be in Antarctica due to the very high sample resolution achieved. This high resolution, through a time period where accurate instrumental measurements of solar activity and climate are available, allows us to examine the response of 10Be concentrations in ice to short-term (monthly to annual) variations in solar activity, and to short-term variations in climate, including seasonality. We find a significant correlation (r2 = 0.56, P < 0.005, n = 92) between observed 10Be concentrations and solar activity (represented by the neutron counting rate). The most pervasive climate influence is a seasonal cycle, which shows maximum concentrations in mid-to-late-summer and minimum concentrations in winter. Model results show reasonable agreement with observations; both a solar activity signal and seasonal cycle in 10Be are captured. However, the modeled snow accumulation rate is too high by approximately 60%. According to the model, the main atmospheric source region of 10Be deposited to Law Dome is the 30-90°S stratosphere (~50%), followed by the 30-90°S troposphere (~30%). An enhancement in the fraction of 10Be arriving to Law Dome from the

Ten-year growth in the scientific production of Brazilian Psychiatry: the impact of the new evaluation policies.

PubMed

Gerolin, Jerônimo; Bressan, Rodrigo A; Pietrobon, Ricardo; Mari, Jair de Jesus

2010-03-01

Developed by the Ministry of Education, the Qualis evaluation criteria have strongly impacted the scientific production of Post-Graduation Programs. A new set of more stringent criteria has been proposed for Qualis. Our aim was to evaluate the impact of the new Qualis criteria on the scientific production of Post-Graduation Programs in psychiatry over the last 10 years. We extracted data from annual reports published between 1998 and 2008, and compared performance measured in terms of the old Qualis rating criteria and the new set of criteria. There was a 25% increase in the number of Information Science Institute-indexed articles in the second five-year period, which rose from 1,213 to 1,518. While, according to the old Qualis criteria, 84% of the Information Science Institute production would have been classified as highly-rated (IF > 1), only 17% of the papers were classified as highly-rated (A1) according to the new Qualis rating criteria. Most papers (65%) were assigned to intermediate categories (B1 and B2) with an IF < 2.29. All psychiatric Post-Graduation Programs have increased their production, but by favoring quality over quantity, the new rules have proved to be more useful for discriminating among the scientific production.

Gender differences in the associations between age trends of social media interaction and well-being among 10-15 year olds in the UK.

PubMed

Booker, Cara L; Kelly, Yvonne J; Sacker, Amanda

2018-03-20

Adolescents are among the highest consumers of social media while research has shown that their well-being decreases with age. The temporal relationship between social media interaction and well-being is not well established. The aim of this study was to examine whether the changes in social media interaction and two well-being measures are related across ages using parallel growth models. Data come from five waves of the youth questionnaire, 10-15 years, of the Understanding Society, the UK Household Longitudinal Study (pooled n = 9859). Social media interaction was assessed through daily frequency of chatting on social websites. Well-being was measured by happiness with six domains of life and the Strengths and Difficulties Questionnaire. Findings suggest gender differences in the relationship between interacting on social media and well-being. There were significant correlations between interacting on social media and well-being intercepts and between social media interaction and well-being slopes among females. Additionally higher social media interaction at age 10 was associated with declines in well-being thereafter for females, but not for males. Results were similar for both measures of well-being. High levels of social media interaction in early adolescence have implications for well-being in later adolescence, particularly for females. The lack of an association among males suggests other factors might be associated with their reduction in well-being with age. These findings contribute to the debate on causality and may inform future policy and interventions.

MMI's Metadata and Vocabulary Solutions: 10 Years and Growing

NASA Astrophysics Data System (ADS)

Graybeal, J.; Gayanilo, F.; Rueda-Velasquez, C. A.

2014-12-01

The Marine Metadata Interoperability project (http://marinemetadata.org) held its public opening at AGU's 2004 Fall Meeting. For 10 years since that debut, the MMI guidance and vocabulary sites have served over 100,000 visitors, with 525 community members and continuous Steering Committee leadership. Originally funded by the National Science Foundation, over the years multiple organizations have supported the MMI mission: "Our goal is to support collaborative research in the marine science domain, by simplifying the incredibly complex world of metadata into specific, straightforward guidance. MMI encourages scientists and data managers at all levels to apply good metadata practices from the start of a project, by providing the best guidance and resources for data management, and developing advanced metadata tools and services needed by the community." Now hosted by the Harte Research Institute at Texas A&M University at Corpus Christi, MMI continues to provide guidance and services to the community, and is planning for marine science and technology needs for the next 10 years. In this presentation we will highlight our major accomplishments, describe our recent achievements and imminent goals, and propose a vision for improving marine data interoperability for the next 10 years, including Ontology Registry and Repository (http://mmisw.org/orr) advancements and applications (http://mmisw.org/cfsn).

Natrelle round silicone breast implants: Core Study results at 10 years.

PubMed

Spear, Scott L; Murphy, Diane K

2014-06-01

Allergan's Natrelle round silicone-filled breast implants were approved by the U.S. Food and Drug Administration in 2006 based on interim results from the Core Study; final 10-year study results are now available. Seven hundred fifteen subjects were implanted with smooth and Biocell textured Natrelle round silicone implants and attended clinic visits at 0 to 4 weeks, 6 months, 1 year, and annually through 10 years. Approximately one-third of subjects underwent magnetic resonance imaging at years 1, 3, 5, 7, and 9 to assess rupture. Complication rates showed modest increases over the previously published 6-year rates. The Kaplan-Meier capsular contracture rate was 18.9 percent for augmentation, 28.7 percent for revision-augmentation, and 24.6 percent for reconstruction. Among augmentation subjects, capsular contracture was significantly lower (p = 0.023) for submuscular (15.7 percent) versus subglandular (26.3 percent) placement. The overall rupture rate in the magnetic resonance imaging cohort was 13.0 percent for subjects and 7.7 percent for implants. By the end of the study, 81.8 percent of augmentation subjects still had an original implant in place. Using a five-point scale, 94.2 percent of augmentation, 83.8 percent of revision-augmentation, and 90.7 percent of reconstruction subjects reported being satisfied or definitely satisfied with their implants. Significant improvement over baseline was also seen in overall breast satisfaction and satisfaction with breast size, shape, feel, and how well they matched. The 10-year data from the Natrelle Core Study, which can guide surgeons and patients in decision-making, demonstrate safety and high levels of patient satisfaction. Therapeutic, III.

NASA Administrator Dan Goldin greets 10-year-old VIP.

NASA Technical Reports Server (NTRS)

2000-01-01

NASA Administrator Dan Goldin (left) watches as 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA, shakes hands with astronaut Dog Wheelock. Behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

Delayed introduction of solid feeding reduces child overweight and obesity at 10 years.

PubMed

Seach, K A; Dharmage, S C; Lowe, A J; Dixon, J B

2010-10-01

The function that the timing of introduction of solid foods may have in the development of child obesity has not been adequately explored, either as a potential confounder of the relationship between breastfeeding and child obesity, or as an independent modifiable risk factor. To determine the association between infant feeding practices and child overweight/obesity. Six hundred and twenty subjects were recruited antenatally from 1990 to 1994. A total of 18 telephone interviews over the first 2 years of life recorded infant feeding practices. At mean age of 10 years, height and weight were measured for 307 subjects. Multiple logistic regression was used to determine whether infant feeding practices (duration of exclusive and any breastfeeding, and age at introduction of solid foods) were associated with odds of being overweight/obese (internationally age- and sex-standardized body mass index category) at age 10 years, after adjustment for confounders. Delayed introduction of solid foods was associated with reduced odds of being overweight/obese at age 10 years, after controlling for socioeconomic status, parental smoking and childcare attendance (adjusted odds ratio (aOR)=0.903 per week, 95% CI=0.841-0.970, P=0.005). Antenatal parental smoking was associated with overweight/obesity at age 10 years (aOR=3.178, 95% CI=1.643-6.147, P=0.001). Duration of exclusive or any breastfeeding was not associated with the outcome. Delayed introduction of solids is associated with reduced odds of child overweight/obesity. Wider promotion of current infant feeding guidelines could have a significant impact on the rates of child overweight and obesity.

500 years of mercury production: global annual inventory by region until 2000 and associated emissions.

PubMed

Hylander, Lars D; Meili, Markus

2003-03-20

2000. Mining is thus still of similar magnitude as all current anthropogenic Hg emissions to the atmosphere, and mined Hg may account for more than one third of these emissions. Also before use, mercury is emitted from Hg mines locally during the mining and refining processes and from mining waste. Global direct emissions to the atmosphere amount to 10-30 t per year currently (up to 10 at Almadén alone), and probably exceed 10000 t historically. Termination of Hg mining will reduce associated local emissions to the atmosphere and biosphere. Since several economically viable Hg-free alternatives exist for practically all applications of Hg, the production and use of Hg can be further reduced and all primary production of Hg other than by-production terminated.

Haiti’s progress in achieving its 10-year plan to eliminate cholera: hidden sickness cannot be cured

PubMed Central

Koski-Karell, Victoria; Farmer, Paul E; Isaac, Benito; Campa, Elizabeth M; Viaud, Loune; Namphy, Paul C; Ternier, Ralph; Ivers, Louise C

2016-01-01

Since the beginning of the cholera epidemic in Haiti 5 years ago, the prevalence of this deadly water-borne disease has fallen far below the initial rates registered during its explosive outset. However, cholera continues to cause extensive suffering and needless deaths across the country, particularly among the poor. The urgent need to eliminate transmission of cholera persists: compared to the same period in 2014, the first 4 months of 2015 saw three times the number of cholera cases. Drawing upon epidemiology, clinical work (and clinical knowledge), policy, ecology, and political economy, and informed by ethnographic data collected in a rural area of Haiti called Bocozel, this paper evaluates the progress of the nation’s 10-year Plan for the Elimination of Cholera. Bocozel is a rice-producing region where most people live in extreme poverty. The irrigation network is decrepit, the land is prone to environmental shocks, fertilizer is not affordable, and the government’s capacity to assist farmers is undermined by resource constraints. When peasants do have rice to sell, the price of domestically grown rice is twice that of US-imported rice. Canal water is not only used to irrigate thousands of acres of rice paddies and sustain livestock, but also to bathe, wash, and play, while water from wells, hand pumps, and the river is used for drinking, cooking, and bathing. Only one out of the three government-sponsored water treatment stations in the research area is still functional and utilized by those who can afford it. Latrines are scarce and often shared by up to 30 people; open defecation remains common. Structural vulnerabilities cut across all sectors – not just water, sanitation, health care, and education, but agriculture, environment, (global and local) commerce, transportation, and governance as well. These are among the hidden sicknesses that impede Haiti and its partners’ capacity to eliminate cholera. PMID:27307774

10 CFR 100.10 - Factors to be considered when evaluating sites.

Code of Federal Regulations, 2013 CFR

2013-01-01

... reactor incorporates unique or unusual features having a significant bearing on the probability or consequences of accidental release of radioactive materials; (4) The safety features that are to be engineered... radioactive fission products. In addition, the site location and the engineered features included as...

10 CFR 100.10 - Factors to be considered when evaluating sites.

Code of Federal Regulations, 2012 CFR

2012-01-01

... reactor incorporates unique or unusual features having a significant bearing on the probability or consequences of accidental release of radioactive materials; (4) The safety features that are to be engineered... radioactive fission products. In addition, the site location and the engineered features included as...

10 CFR 100.10 - Factors to be considered when evaluating sites.

Code of Federal Regulations, 2014 CFR

2014-01-01

... reactor incorporates unique or unusual features having a significant bearing on the probability or consequences of accidental release of radioactive materials; (4) The safety features that are to be engineered... radioactive fission products. In addition, the site location and the engineered features included as...

Validation of ‘POIBA-How do we eat?’ questionnaire in 9-10 years old schoolchildren

PubMed Central

Ariza, Carles; Arechavala, Teresa; Valmayor, Sara; Serral, Gemma; Moncada, Albert; Rajmil, Luis; Schiaffino, Anna; Sánchez-Martínez, Francesca

2017-01-01

ABSTRACT Background: It is difficult to obtain good food reports with Food Frequency Questionnaires (FFQ) among children. In addition, validated questionnaires are scarce. Objective: The aim of this study was to validate the ‘POIBA-How do we eat?’ (POIBA-HDWE) FFQ and whether it could be administered to children under 10 years of age. Design: We validated the FFQ POIBA-HDWE as part of the Childhood Obesity Prevention Program (POIBA project) in Barcelona. Forty-two out of 63 primary school students (9–10 years old) answered three questionnaires: FFQ POBA-HDWE; another questionnaire, ‘POIBA-How do our children eat?’ (POIBA-HDOCE), which was administered to the children’s parents; and the 24-h recall computer program ‘Young Adolescents’ Nutrition Assessment on Computer’ (YANA-C), which was used on three different days as a gold standard. We tested for correlations using the Spearman test for non-parametric variables. Results: We found low compliance with food recommendations (<50%). The POIBA-HDWE and POIBA-HDOCE questionnaires showed a moderate correlation for soft drinks (r = 0.49; p < 0.01), nuts (r = 0.59; p < 0.01), dairy products (r = 0.41; p < 0.01) and juices (r = 0.49; p < 0.01). There were moderate correlations between POIBA-HDWE and YANA-C for fried potatoes (r = 0.42; p = 0.01), dairy products (r = 0.53; p < 0.01), juices (r = 0.41; p < 0.01), and grains(r = 0.50; p < 0.01). Food frequency questions showed a homogeneity of 0.69, and a sensitivity of over 60% for all food items except chips (37.5%) and sweets (51.7%). Conclusions: The POIBA-HDWE FFQ showed moderate correlations with the gold standard, high sensitivity for most food types and acceptable internal consistency. It is an easy and affordable tool for recording food frequency in children under 10 years old. PMID:29151829

Atypical presentation of macrophagic myofasciitis 10 years post vaccination.

PubMed

Ryan, Aisling M; Bermingham, Niamh; Harrington, Hugh J; Keohane, Catherine

2006-12-01

Macrophagic myofasciitis (MMF) is an uncommon inflammatory disorder of muscle believed to be due to persistence of vaccine-derived aluminium hydroxide at the site of injection. The condition is characterised by diffuse myalgias, arthralgia and fatigue. We describe a patient with histologically confirmed MMF whose presentation was atypical with left chest and upper limb pain beginning more than 10 years post vaccination. Treatment with steroids led to symptomatic improvement. Although rare, clinicians should consider MMF in cases of atypical myalgia.

River fluxes to the sea from the oceanʼs 10Be/9Be ratio

NASA Astrophysics Data System (ADS)

von Blanckenburg, Friedhelm; Bouchez, Julien

2014-02-01

The ratio of the meteoric cosmogenic radionuclide 10Be to the stable isotope 9Be is proposed here to be a flux proxy of terrigenous input into the oceans. The ocean's dissolved 10Be/9Be is set by (1) the flux of meteoric 10Be produced in the atmosphere; (2) the denudational flux of the rivers discharging into a given ocean basin; (3) the fraction of 9Be that is released from primary minerals during weathering (meaning the 9Be transported by rivers in either the dissolved form or adsorbed onto sedimentary particles and incorporated into secondary oxides); and (4) the fraction of riverine 10Be and 9Be actually released into seawater. Using published 10Be/9Be data of rivers for which independent denudation rate estimates exist we first find that the global average fraction of 9Be released during weathering into river waters and their particulate load is 20% and does not depend on denudation rate. We then evaluate this quantitative proxy for terrigenous inputs by using published dissolved seawater Be isotope data and a compilation of global river loads. We find that the measured global average oceanic dissolved 10Be/9Be ratio of about 0.9×10-7 is satisfied by the mass balance if only about 6% of the dissolved and adsorbed riverine Be is eventually released to the open ocean after escaping the coastal zone. When we establish this mass balance for individual ocean basins good agreement results between 10Be/9Be ratios predicted from known river basin denudation rates and measured ocean 10Be/9Be ratios. Only in the South Atlantic and the South Pacific the 10Be/9Be ratio is dominated by advected Be and in these basins the ratio is a proxy for ocean circulation. As the seawater 10Be/9Be ratio is faithfully recorded in marine chemical precipitates the 10Be/9Be ratio extracted from authigenic sediments can now serve to estimate relative changes in terrigenous input into the oceans back through time on a global and on an ocean basin scale.

Past and next 10 years of medical informatics.

PubMed

Ückert, Frank; Ammenwerth, Elske; Dujat, Carl; Grant, Andrew; Haux, Reinhold; Hein, Andreas; Hochlehnert, Achim; Knaup-Gregori, Petra; Kulikowski, Casimir; Mantas, John; Maojo, Victor; Marschollek, Michael; Moura, Lincoln; Plischke, Maik; Röhrig, Rainer; Stausberg, Jürgen; Takabayashi, Katsuhiko; Winter, Alfred; Wolf, Klaus-Hendrik; Hasman, Arie

2014-07-01

More than 10 years ago Haux et al. tried to answer the question how health care provision will look like in the year 2013. A follow-up workshop was held in Braunschweig, Germany, for 2 days in May, 2013, with 20 invited international experts in biomedical and health informatics. Among other things it had the objectives to discuss the suggested goals and measures of 2002 and how priorities on MI research in this context should be set from the viewpoint of today. The goals from 2002 are now as up-to-date as they were then. The experts stated that the three goals: "patient-centred recording and use of medical data for cooperative care"; "process-integrated decision support through current medical knowledge" and "comprehensive use of patient data for research and health care reporting" have not been reached yet and are still relevant. A new goal for ICT in health care should be the support of patient centred personalized (individual) medicine. MI as an academic discipline carries out research concerning tools that support health care professionals in their work. This research should be carried out without the pressure that it should lead to systems that are immediately and directly accepted in practice.

Eating habits and caloric intake of physically active young boys, ages 10 to 14 years.

PubMed

Thomson, M J; Cunningham, D A; Wearring, G A

1980-03-01

Eating habits of 104 male participants (ages 10 to 14 years) in organized ice hockey were compared across age groups and levels of competition. The boys were members of either a highly skilled and intensively active competitive league group (CL) or a less skilled, moderately active house league group (HL). Eating habits were recorded during a school day from a 24 hour recall questionnaire administered by a trained interviewer. The types and amounts of foods eaten were recorded and caloric intake was calculated. The total caloric intakes were not significantly different by age or competitive group. The boys had higher caloric intakes by age (200 kcal day-1) than reported by other studies but the caloric intake by kilogram of body weight was similar. There was a trend towards larger caloric intake by the CL boys (ages 10 and 11 years), however when divided by body weight the differences were not significant suggesting that this trend was due to a greater body weight of the CL boys and not a significantly increased caloric expenditure. The types of foods eaten (fruit, vegetables, dairy, meat, bread or "empty calories") were similar for the two activity groups and across ages 10 to 14 years. The caloric intakes of dairy and meat products of both groups were significantly higher than for the other food groups.

Loess 10Be evidence for an asynchronous Brunhes-Matuyama magnetic polarity reversal

NASA Astrophysics Data System (ADS)

Zhou, Weijian; Beck, J. Warren; Kong, Xianghui; An, Zhisheng; Qiang, Xiaoke; Wu, Zhenkun; Xian, Feng; Ao, Hong

2015-04-01

In Chinese loess the Brunhes-Matuyama (B-M) geomagnetic reversal appears to occur about 25 ka prior to the established axial dipole reversal age found in many marine sediments, i.e., in Chinese loess this magnetic reversal boundary is found in glacial loess unit L8 which is thought to be correlated with Marine Isotope Stage 20 (MIS 20), in marine sediment records, however, this boundary is commonly found in interglacial period of MIS 19 (Tauxe et al., 1996; Zhou and Shackleton, 1999), leading to the debate on uncertainties of paleoclimatic correlation between the Chinese loess-paleosol sequences and marine sediments (Wang et al., 2006; Liu et al., 2008; Jin and Liu, 2011). Based on this issue, here we propose to use the cosmogenic 10Be to address this conundrum. 10Be is a long-lived radionuclide produced in the atmosphere by cosmic ray spallation reactions and carried to the ground attached to aerosols. Its atmospheric production rate is inversely proportional to the geomagnetic field intensity (Masarik and Beer, 1999). This allows us to reconstruct past geomagnetic field intensity variations using 10Be concentrations recorded in different sedimentary archives. We carried out both the 10Be studies and paleogeomagnetic measurements in Luochuan and Xifeng sections in Chinese Loess Plateau. Both loess profiles show that 10Be production rate was at a maximum-an indication of the dipole field reversal-at ca. 780 ± 3 ka BP., in paleosol unit S7 corresponding to MIS 19, proving that the timing of B-M reversal recorded in Chinese loess is synchronous with that seen in marine records (Tauxe et al., 1996). These results reaffirmed the conventional paleoclimatic correlation of loess-paleosol sequences with marine isotope stages and the standard loess timescale as correct. However, it is ~25 ka younger than the age (depth) of the paleogeomagnetic measurements which show that the B-M boundary is in L8 in these two Chinese loess-paleosol sequences, demonstrating that loess

10 CFR 719.10 - What information must be included in the legal management plan?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false What information must be included in the legal management plan? 719.10 Section 719.10 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Legal Management Plan § 719.10 What information must be included in the legal management plan? The legal management...

10 CFR 719.10 - What information must be included in the legal management plan?

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false What information must be included in the legal management plan? 719.10 Section 719.10 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Legal Management Plan § 719.10 What information must be included in the legal management plan? The legal management...

10 CFR 719.10 - What information must be included in the legal management plan?

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false What information must be included in the legal management plan? 719.10 Section 719.10 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Legal Management Plan § 719.10 What information must be included in the legal management plan? The legal management...

True fir spacing trials: 10-year results.

Treesearch

Robert O. Curtis

2008-01-01

Eighteen precommercial thinning trials were established in true fir-hemlock stands in the Olympic Mountains and the west side of the Cascade Range during the period 1987 through 1994. This paper updates a previous report, with results for the first 10 years after establishment. Results are given for (1) all trees, (2) the largest 80 per acre of any species, and (3)...

A First-Year Teacher's Top 10 Mistakes

ERIC Educational Resources Information Center

Nourie, Meredith C.

2011-01-01

In June the author completed her first full year of high school teaching. In this article, she shares her top 10 mistakes for several reasons: (1) so that other beginners will know what to expect; (2) so that teacher educators will share with candidates for licensure; (3) so that she won't make the same mistakes again; (4) so that veteran teachers…

A 10-Year Follow-Up Study of a Japanese Family with Ferroportin Disease A: Mild Iron Overload with Mild Hyperferritinemia Co-Occurring with Hyperhepcidinemia May be Benign.

PubMed

Hayashi, Hisao; Yano, Motoyoshi; Urawa, Naohito; Mizutani, Akane; Hamaoka, Shima; Araki, Jun; Kojima, Yuji; Naito, Yutaka; Kato, Ayako; Tatsumi, Yasuaki; Kato, Koichi

2018-05-18

This is a 10-year follow-up study of a family with ferroportin disease A. The proband, a 59-year-old man showed no noteworthy findings with the exception of an abnormal iron level. The proband's 90-year-old father showed reduced abilities in gait and cognition; however, with the exception of his iron level, his biochemistry results were almost normal. Brain imaging showed age-matched atrophy and iron deposition. In both patients, the serum levels of ferritin and hepcidin25, and liver CT scores declined over a 10-year period. These changes were mainly due to a habitual change to a low-iron diet. The iron disorder in this family was not associated with major organ damage.

Findings from a Pilot Study into Student Retention beyond Year 10

ERIC Educational Resources Information Center

Cranston, Neil; Allen, Jeanne Maree; Watson, Jane; Hay, Ian; Beswick, Kim

2012-01-01

This paper reports on early findings from a pilot study into student retention beyond Year 10. Located in rural, regional and disadvantaged communities in Tasmania, the research has implications at State, national and international levels. It is being funded by a nationally competitive Australian Research Council Linkage grant and the Tasmanian…

Total knee replacement-cementless tibial fixation with screws: 10-year results.

PubMed

Ersan, Önder; Öztürk, Alper; Çatma, Mehmet Faruk; Ünlü, Serhan; Akdoğan, Mutlu; Ateş, Yalım

2017-12-01

The aim of this study was to evaluate the long term clinical and radiological results of cementless total knee replacement. A total of 51 knees of 49 patients (33 female and 16 male; mean age: 61.6 years (range, 29-66 years)) who underwent TKR surgery with a posterior stabilized hydroxyapatite coated knee implant were included in this study. All of the tibial components were fixed with screws. The HSS scores were examined preoperatively and at the final follow-up. Radiological assessment was performed with Knee Society evaluating and scoring system. Kaplan-Meier survival analysis was performed to rule out the survival of the tibial component. The mean HSS scores were 45.8 (range 38-60) and 88.1 (range 61-93), preoperatively and at the final follow-up respectively. Complete radiological assessment was performed for 48 knees. Lucent lines at the tibial component were observed in 4 patients; one of these patients underwent a revision surgery due to the loosening of the tibial component. The 10-year survival rate of a tibial component was 98%. Cementless total knee replacement has satisfactory long term clinical results. Primary fixation of the tibial component with screws provides adequate stability even in elderly patients with good bone quality. Level IV, Therapeutic study. Copyright © 2017 Turkish Association of Orthopaedics and Traumatology. Production and hosting by Elsevier B.V. All rights reserved.

IL-10 Gene Polymorphisms Are Associated with Post-Bronchiolitis Lung Function Abnormalities at Six Years of Age

PubMed Central

Lauhkonen, Eero; Koponen, Petri; Teräsjärvi, Johanna; Gröndahl-Yli-Hannuksela, Kirsi; Vuononvirta, Juho; Nuolivirta, Kirsi; Toikka, Jyri O.; Helminen, Merja; He, Qiushui; Korppi, Matti

2015-01-01

Aim Interleukin-10 (IL-10) has been associated with wheezing and asthma in children and the genetic variation of the IL-10 cytokine production may be linked to post-bronchiolitis lung function. We used impulse oscillometry (IOS) to evaluate the associations of IL10 polymorphisms with lung function at a median age of 6.3 years in children hospitalised for bronchiolitis before six months of age. Methods We performed baseline and post-exercise IOS on 103 former bronchiolitis patients. Data on single nucleotide polymorphisms (SNP) of IL10 rs1800896 (–1082G/A), rs1800871 (–819C/T), rs1800872 (–592C/A) were available for 99 children and of IL10 rs1800890 (–3575T/A) for 98 children. Results IL10 rs1800896, rs1800871 and rs1800872 combined genotype AA+CT+CA and carriage of haplotype ATA, respectively, were associated with higher resistance and lower reactance in baseline IOS in adjusted analyses. At IL10 rs1800890, the A/A-genotype and carriers of A-allele were associated with lower reactance in baseline IOS. There were no significant associations between the studied SNPs and airway hyper-reactivity to exercise. Conclusion Low-IL-10-producing polymorphisms in the IL-10 encoding gene were associated with obstructive lung function parameters, suggesting an important role for IL-10 in development of lung function deficit in early bronchiolitis patients. PMID:26473365

Dysthymic Disorder and Double Depression: Prediction of 10-Year Course Trajectories and Outcomes

PubMed Central

Klein, Daniel N.; Shankman, Stewart A.; Rose, Suzanne

2008-01-01

We sought to identify baseline predictors of 10-year course trajectories and outcomes in patients with dysthymic disorder and double depression. Eighty-seven outpatients with early-onset (< 21 years) dysthymic disorder, with or without superimposed major depression, were assessed five times at 30-month intervals for 10 years. Baseline evaluations included semi-structured diagnostic interviews for Axis I and II psychopathology and childhood adversity. Direct interview and family history data were collected on first-degree relatives. Follow-up assessments included the Longitudinal Follow-up Evaluation and Hamilton Depression Rating Scale. Using mixed effects growth curve models, univariate predictors of depression severity and functional impairment at 10-year outcome included older age, less education, concurrent anxiety disorder, greater familial loading for chronic depression, a history of a poorer maternal relationship in childhood, and a history of childhood sexual abuse. In addition, longer duration of dysthymic disorder also predicted greater impairment 10 years later. Predictors of a poorer trajectory of depressive symptoms over time included ethnicity and personality disorders; predictors of a poorer trajectory of social functioning included familial loading of chronic depression and quality of the childhood maternal relationship. Thus, demographic, clinical, family history, and early adversity variables all contribute to predicting the long term trajectory and outcome of DD. These variables should be routinely assessed in clinical evaluations and can provide clinicians with valuable prognostic information. PMID:17466334

Dysthymic disorder and double depression: prediction of 10-year course trajectories and outcomes.

PubMed

Klein, Daniel N; Shankman, Stewart A; Rose, Suzanne

2008-04-01

We sought to identify baseline predictors of 10-year course trajectories and outcomes in patients with dysthymic disorder and double depression. Eighty-seven outpatients with early-onset (<21 years) dysthymic disorder, with or without superimposed major depression, were assessed five times at 30-month intervals for 10 years. Baseline evaluations included semi-structured diagnostic interviews for Axis I and II psychopathology and childhood adversity. Direct interview and family history data were collected on first-degree relatives. Follow-up assessments included the Longitudinal Follow-up Evaluation and Hamilton Depression Rating Scale. Using mixed effects growth curve models, univariate predictors of depression severity and functional impairment at 10-year outcome included older age, less education, concurrent anxiety disorder, greater familial loading for chronic depression, a history of a poorer maternal relationship in childhood, and a history of childhood sexual abuse. In addition, longer duration of dysthymic disorder also predicted greater impairment 10 years later. Predictors of a poorer trajectory of depressive symptoms over time included ethnicity and personality disorders; predictors of a poorer trajectory of social functioning included familial loading of chronic depression and quality of the childhood maternal relationship. Thus, demographic, clinical, family history, and early adversity variables all contribute to predicting the long-term trajectory and outcome of DD. These variables should be routinely assessed in clinical evaluations and can provide clinicians with valuable prognostic information.

10-year results of a new low-monomer cement: follow-up of a randomized RSA study.

PubMed

Söderlund, Per; Dahl, Jon; Röhrl, Stephan; Nivbrant, Bo; Nilsson, Kjell G

2012-12-01

The properties and performance of a new low-monomer cement were examined in this prospective randomized, controlled RSA study. 5-year data have already been published, showing no statistically significant differences compared to controls. In the present paper we present the 10-year results. 44 patients were originally randomized to receive total hip replacement with a Lubinus SPII titanium-aluminum-vanadium stem cemented either with the new Cemex Rx bone cement or with control bone cement, Palacos R. Patients were examined using RSA, Harris hip score, and conventional radiographs. At 10 years, 33 hips could be evaluated clinically and 30 hips could be evaluated with RSA (16 Cemex and 14 Palacos). 9 patients had died and 4 patients were too old or infirm to be investigated. Except for 1 hip that was revised for infection after less than 5 years, no further hips were revised before the 10-year follow-up. There were no statistically significant clinical differences between the groups. The Cemex cement had magnitudes of migration similar to or sometimes lower than those of Palacos cement. In both groups, most hips showed extensive radiolucent lines, probably due to the use of titanium alloy stems. At 10 years, the Cemex bone cement tested performed just as well as the control (Palacos bone cement).

The Beryllium-10 Abundance in an Unusual Hibonite-Perovskite Refractory Inclusion from Allende: Implications for the Origin of Be-10

NASA Technical Reports Server (NTRS)

Liu, M-C.; Keller, L. P.

2017-01-01

Beryllium-10 (decays to B-10, t1/2 = t(sub 1/2) = 1.3 Myr) 1.3 Myr) is a radionuclide that exclusively requires a is a radionuclide that exclusively requires a spallation origin. Therefore, one could obtain important insights into the irradiation environment in the solar nebula by understanding the distribution and abundance of this radionuclide in meteoritic inclusions. Most previous data are derived from B isotopic analysis of coarse-grained CV3 Ca-Al-rich Inclusions (CAIs) that have AL-26.Al-27 Al close to the canonical level of 5 x 10 (exp -5) and inferred Be-10/Be-9 ratios between 4 x 10(exp -4) and 1 x 10 (exp -2=3) [1-5]. Al-26-depleted FUN (Fractionaed and Unknown Nuclear anomalies) CAIs are less studied due to their rarity. FUN CAIs are thought to have formed prior to homogenization of Al-26/Al-27 Al and stable isotope anomalies (e.g., Ti-50) in the solar nebula, and thus represent one of the oldest Solar System solids [6]. So far, only three FUN CAIs (Axtell 2771, KT-1 and HAL) from CV3 chondrites have been measured for Be-10. They are characterized by variable Be-10/Be-9 ratios between (2.7-4.4) × 10(exp -4) [4,7]. Another group of rare, Al-26-free and and isotopically more anomalous inclusions, namely platy hibonite crystals (PLACs) from CM2 chondrites, have well-defined Be-10/Be-9 = (5.3 +/- 1.0) x 10 (exp -4) [9]. Al-26-free CAIs appear to have lower Be-1-/Be-9 than Al-26-bearing CAIs, although large analytical errors associated with some data would allow for an apparent overlap. It has been argued that the observed Be-10 variation resulted from the in-situ production of this radionuclide in CAIs (or their precursors) by irradiation, and the ratio difference simply reflects the fluctuation in projectile fluences [e.g., 9]. Another observation in support of this explanation comes from these CAIs' initial B-10/B-11 ratios, most of which are higher than the chondritic value 0.2478 [10]. This has been interpreted as a result of mixing between spallogenic

NASA Administrator Dan Goldin greets 10-year-old VIP.

NASA Technical Reports Server (NTRS)

2000-01-01

NASA Administrator Dan Goldin (left) listens intently to 10-year- old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. Behind Goldin is astronaut Doug Wheelock; behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS- 99.

NASA Administrator Dan Goldin greets 10-year-old VIP.

NASA Technical Reports Server (NTRS)

2000-01-01

NASA Administrator Dan Goldin (left) shares a light moment during his meeting with 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. Behind Goldin is astronaut Doug Wheelock; behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

NASA Administrator Dan Goldin greets 10-year-old VIP.

NASA Technical Reports Server (NTRS)

2000-01-01

NASA Administrator Dan Goldin (left) shares a laugh with VIP 10- year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. Behind Goldin is astronaut Doug Wheelock; behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS- 99.

Spectacle prescribing among 10-year-old children.

PubMed Central

Stewart-Brown, S

1985-01-01

Between 10 and 12% of the 10-year-old children in the 1970 national birth cohort were prescribed a pair of spectacles. One-fifth of these children had no impairment of visual acuity and a further 15-20% had only minimal visual defects. Only two-thirds of children with spectacles could produce them when asked to do so at the survey school medical examination; this was particularly common among those in the lower social classes and among children who had no detectable impairment. The information presented in this paper combined with that from earlier national birth cohort studies suggests that overprescribing of spectacles to school children is very common. The financial implications of this overprescribing are discussed. PMID:4084477

Drivers of inter-year variability of plant production and decomposers across contrasting island ecosystems.

PubMed

Wardle, David A; Jonsson, Micael; Kalela-Brundin, Maarit; Lagerström, Anna; Bardgett, Richard D; Yeates, Gregor W; Nilsson, Marie-Charlotte

2012-03-01

Despite the likely importance of inter-year dynamics of plant production and consumer biota for driving community- and ecosystem-level processes, very few studies have explored how and why these dynamics vary across contrasting ecosystems. We utilized a well-characterized system of 30 lake islands in the boreal forest zone of northern Sweden across which soil fertility and productivity vary considerably, with larger islands being more fertile and productive than smaller ones. In this system we assessed the inter-year dynamics of several measures of plant production and the soil microbial community (primary consumers in the decomposer food web) for each of nine years, and soil microfaunal groups (secondary and tertiary consumers) for each of six of those years. We found that, for measures of plant production and each of the three consumer trophic levels, inter-year dynamics were strongly affected by island size. Further, many variables were strongly affected by island size (and thus bottom-up regulation by soil fertility and resources) in some years, but not in other years, most likely due to inter-year variation in climatic conditions. For each of the plant and microbial variables for which we had nine years of data, we also determined the inter-year coefficient of variation (CV), an inverse measure of stability. We found that CVs of some measures of plant productivity were greater on large islands, whereas those of other measures were greater on smaller islands; CVs of microbial variables were unresponsive to island size. We also found that the effects of island size on the temporal dynamics of some variables were related to inter-year variability of macroclimatic variables. As such, our results show that the inter-year dynamics of both plant productivity and decomposer biota across each of three trophic levels, as well as the inter-year stability of plant productivity, differ greatly across contrasting ecosystems, with potentially important but largely overlooked

Risk factors for revision within 10 years of total knee arthroplasty.

PubMed

Dy, Christopher J; Marx, Robert G; Bozic, Kevin J; Pan, Ting Jung; Padgett, Douglas E; Lyman, Stephen

2014-04-01

institutional characteristics affect the risk for revision within 10 years of index TKA. These data can be used to develop process improvement and implant surveillance strategies among high-risk patients. Level III, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

7 CFR 1424.10 - Succession and control of facilities and production.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

7 CFR 1424.10 - Succession and control of facilities and production.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

7 CFR 1424.10 - Succession and control of facilities and production.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

7 CFR 1424.10 - Succession and control of facilities and production.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

7 CFR 1424.10 - Succession and control of facilities and production.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

National SAFE KIDS Campaign releases 10-year report.

PubMed

Pike-Paris, A

1999-01-01

Unintentional injury is the leading cause of death and disability in children 14 years and under. The National SAFE KIDS Campaign, a nationwide organization aimed at education and prevention of unintentional injury, recently released its 10-year report that describes areas of success, areas in need of improvement, and goals for the future. The full 61-page report is worthy of reading and referencing for all those involved with children and their health care. Highlights of the report are summarized below.

Consumption of dairy products and the 15-year incidence of age-related macular degeneration.

PubMed

Gopinath, Bamini; Flood, Victoria M; Louie, Jimmy C Y; Wang, Jie Jin; Burlutsky, George; Rochtchina, Elena; Mitchell, Paul

2014-05-01

Habitual consumption of dairy products has been shown to play an important role in the prevention of several chronic diseases. We aimed to prospectively assess the relationship between the change in dairy product consumption (both regular fat and low/reduced fat) and the 15-year incidence of age-related macular degeneration (AMD). In the Blue Mountains Eye Study, 2037 participants aged 49 years or above at baseline were re-examined at follow-up in 1997-9, 2002-4 and/or 2007-9. AMD was assessed from retinal photographs. Dietary data were collected using a semi-quantitative FFQ, and servings of dairy product consumption calculated. Over the 15-year follow-up, there were 352, 268 and eighty-four incident cases of any, early and late AMD, respectively. After adjusting for age, sex, current smoking, white cell count and fish consumption, a significant linear trend (P for trend = 0·003) was observed with decreasing consumption of total dairy foods and the 15-year incidence of late AMD, comparing the lowest v. highest quintile of intake (OR 2·80, 95 % CI 1·21, 3·04). Over the 15 years, decreased consumption of reduced-fat dairy foods was associated with an increased risk of incident late AMD, comparing the lowest to highest quintile of intake (OR 3·10, 95 % CI 1·18, 8·14, P for trend = 0·04). Decreasing total dietary Ca intake over the 15 years was also associated with an increased risk of developing incident late AMD (multivariable-adjusted P for trend = 0·03). A lower consumption of dairy products (regular and low fat) and Ca was independently associated with a higher risk of developing incident late AMD in the long term. Additional cohort studies are needed to confirm these findings.

Polymer-impregnated bridge slabs : performance over 10 years.

DOT National Transportation Integrated Search

1990-01-01

This report presents the results of a study to evaluate the performance over a 10-year period of slabs that were impregnated to a depth of about 1 in with a monomer that was subsequently polymerized (shallow polymer impregnation). The slabs were used...

Factors predicting high estimated 10-year stroke risk: thai epidemiologic stroke study.

PubMed

Hanchaiphiboolkul, Suchat; Puthkhao, Pimchanok; Towanabut, Somchai; Tantirittisak, Tasanee; Wangphonphatthanasiri, Khwanrat; Termglinchan, Thanes; Nidhinandana, Samart; Suwanwela, Nijasri Charnnarong; Poungvarin, Niphon

2014-08-01

The purpose of the study was to determine the factors predicting high estimated 10-year stroke risk based on a risk score, and among the risk factors comprising the risk score, which factors had a greater impact on the estimated risk. Thai Epidemiologic Stroke study was a community-based cohort study, which recruited participants from the general population from 5 regions of Thailand. Cross-sectional baseline data of 16,611 participants aged 45-69 years who had no history of stroke were included in this analysis. Multiple logistic regression analysis was used to identify the predictors of high estimated 10-year stroke risk based on the risk score of the Japan Public Health Center Study, which estimated the projected 10-year risk of incident stroke. Educational level, low personal income, occupation, geographic area, alcohol consumption, and hypercholesterolemia were significantly associated with high estimated 10-year stroke risk. Among these factors, unemployed/house work class had the highest odds ratio (OR, 3.75; 95% confidence interval [CI], 2.47-5.69) followed by illiterate class (OR, 2.30; 95% CI, 1.44-3.66). Among risk factors comprising the risk score, the greatest impact as a stroke risk factor corresponded to age, followed by male sex, diabetes mellitus, systolic blood pressure, and current smoking. Socioeconomic status, in particular, unemployed/house work and illiterate class, might be good proxy to identify the individuals at higher risk of stroke. The most powerful risk factors were older age, male sex, diabetes mellitus, systolic blood pressure, and current smoking. Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.

Cosmogenic 10Be Dating of Early and Latest Holocene Moraines on Nevado Salcantay in the Southern Peruvian Andes

NASA Astrophysics Data System (ADS)

Licciardi, J. M.; Schaefer, J. M.; Lund, D. C.

2007-12-01

A two-fold sequence of nested lateral and end moraines was mapped in a glacial trough emanating from the southwest flank of Nevado Salcantay (6271 m; ~13°S latitude), the highest peak in the Cordillera Vilcabamba of southern Peru. The field area is situated 25 km due south of the archaeological site of Machu Picchu. Outer and inner moraines in the sequence were deposited by valley glaciers that terminated ~5 km and ~3 km, respectively, from their headwall on the Salcantay summit massif. Cosmogenic 10Be surface exposure dating of granitic boulders sampled on the Salcantay moraines is underway and has provided the first numerical ages for these deposits. Initial results indicate ages of 8.1 ± 0.1 10Be ka for the outer moraine and 200 ± 20 10Be years for the sharp-crested inner moraine. These ages are derived using the CRONUS-Earth 10Be exposure age calculator (version 2.0) and expressed with respect to the Lal- Stone production rate scaling scheme using the standard atmosphere. The outer and inner moraine ages correspond to glacial events during the early and latest Holocene, respectively. Further 10Be dating of the mapped moraines and similar deposits observed in adjacent drainages on Nevado Salcantay is anticipated to yield a high-resolution chronology of valley glaciation in this segment of the southern Peruvian Andes. The new results bridge an important gap between existing Andean glacier records to the north and south, and complement available ice core and lacustrine paleoclimate records in the vicinity, thereby expanding spatial and temporal coverage for identifying patterns of Holocene climate change in the tropical Andes. Notably, the inner moraine age correlates with the timing of the Little Ice Age as defined in northern mid- and high latitude glacier records, and suggests considerable expansion of valley glaciers in the southern Peruvian Andes during this climatic minimum. Apart from their paleoclimatic significance, the initial results also demonstrate

Evolution of migraine after a 10-year follow-up.

PubMed

Nachit-Ouinekh, Fatima; Dartigues, Jean-François; Chrysostome, Virginie; Henry, Patrick; Sourgen, Christophe; El Hasnaoui, Abdelkader

2005-01-01

To assess the evolution of headaches in a workplace cohort over a 10-year period. Migraine headaches are associated with significant handicap in everyday activities and poor quality of life. The prevalence of migraine shows a bell-shaped age distribution with a peak during the third and fourth decades. However, there is little longitudinal data available on the natural history of this condition. A prospective health survey undertaken in a large workplace cohort since 1989 provides an opportunity to assess the evolution of migraine and other headache syndromes over a 10-year period. A sample of 2500 subjects who reported regular headaches was chosen at random from those with headache identified in a cohort of 46,244 employees of the French national power company aged between 35 and 50 years in 1989 participating in a yearly health survey. In 1993, all subjects were sent a headache questionnaire to complete and return. In 2003, an identical questionnaire was sent to all subjects who had returned exploitable data in 1993. Headache diagnosis was assigned retrospectively using the International Headache Society (IHS) criteria to migraine (IHS categories 1.1 and 1.2), migrainous disorder (IHS category 1.7), or other episodic headaches. Of 2500 subjects sampled, 2051 (82%) returned exploitable data for the first questionnaire in 1993. In 2003, 1250 (61%) of these provided a second data set. In 1993, 623 (30.4%) of subjects fulfilled diagnostic criteria for migraine. However, only 37% of these retained the diagnosis 10 years later. In contrast, the proportion of subjects with other forms of episodic headache rose from 23.7% to 31.6%. In 2003, 9.5% of the sample were headache-free. Retention or acquisition of a diagnosis of migraine was more common in women than in men, and age was associated with evolution to a less severe headache syndrome. In those subjects who continued to have headaches, frequency and severity were lower at the second assessment. Only a minority of

Evaluating steady-state soil thickness by coupling uranium series and 10Be cosmogenic radionuclides

NASA Astrophysics Data System (ADS)

Vanacker, Veerle; Schoonejans, Jerome; Opfergelt, Sophie; Granet, Matthieu; Christl, Marcus; Chabaux, Francois

2017-04-01

Within the Critical Zone, the development of the regolith mantle is controlled by the downwards propagation of the weathering front into the bedrock and denudation at the surface of the regolith by mass movements, water and wind erosion. When the removal of surface material is approximately balanced by the soil production, the soil system is assumed to be in steady-state. The steady state soil thickness (or so-called SSST) can be considered as a dynamic equilibrium of the system, where the thickness of the soil mantle stays relatively constant over time. In this study, we present and compare analytical data from two independent isotopic techniques: in-situ produced cosmogenic nuclides and U-series disequilibria to constrain soil development under semi-arid climatic conditions. The Spanish Betic Cordillera (Southeast Spain) was selected for this study, as it offers us a unique opportunity to analyze soil thickness steady-state conditions for thin soils of semiarid environments. Three soil profiles were sampled across the Betic Ranges, at the ridge crest of zero-order catchments with distinct topographic relief, hillslope gradient and 10Be-derived denudation rate. The magnitude of soil production rates determined based on U-series isotopes (238U, 234U, 230Th and 226Ra) is in the same order of magnitude as the 10Be-derived denudation rates, suggesting steady state soil thickness in two out of three sampling sites. The results suggest that coupling U-series isotopes with in-situ produced radionuclides can provide new insights in the rates of soil development; and also illustrate the potential frontiers in applying U-series disequilibria to track soil production in rapidly eroding landscapes characterized by thin weathering depths.

A probabilistic model framework for evaluating year-to-year variation in crop productivity

NASA Astrophysics Data System (ADS)

Yokozawa, M.; Iizumi, T.; Tao, F.

2008-12-01

Most models describing the relation between crop productivity and weather condition have so far been focused on mean changes of crop yield. For keeping stable food supply against abnormal weather as well as climate change, evaluating the year-to-year variations in crop productivity rather than the mean changes is more essential. We here propose a new framework of probabilistic model based on Bayesian inference and Monte Carlo simulation. As an example, we firstly introduce a model on paddy rice production in Japan. It is called PRYSBI (Process- based Regional rice Yield Simulator with Bayesian Inference; Iizumi et al., 2008). The model structure is the same as that of SIMRIW, which was developed and used widely in Japan. The model includes three sub- models describing phenological development, biomass accumulation and maturing of rice crop. These processes are formulated to include response nature of rice plant to weather condition. This model inherently was developed to predict rice growth and yield at plot paddy scale. We applied it to evaluate the large scale rice production with keeping the same model structure. Alternatively, we assumed the parameters as stochastic variables. In order to let the model catch up actual yield at larger scale, model parameters were determined based on agricultural statistical data of each prefecture of Japan together with weather data averaged over the region. The posterior probability distribution functions (PDFs) of parameters included in the model were obtained using Bayesian inference. The MCMC (Markov Chain Monte Carlo) algorithm was conducted to numerically solve the Bayesian theorem. For evaluating the year-to-year changes in rice growth/yield under this framework, we firstly iterate simulations with set of parameter values sampled from the estimated posterior PDF of each parameter and then take the ensemble mean weighted with the posterior PDFs. We will also present another example for maize productivity in China. The

Self-Esteem during University Studies Predicts Career Characteristics 10 Years Later

ERIC Educational Resources Information Center

Salmela-Aro, Katariina; Nurmi, Jari-Erik

2007-01-01

To examine how self-esteem measured during university studies would impact on the characteristics of the work career 10 years later, 297 university students completed the Rosenberg's self-esteem inventory four times while at university and various career-related questionnaires 10 years later. Latent Growth Curve Modeling showed that a high overall…

29 CFR 788.10 - “Preparing * * * other forestry products.”

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false âPreparing * * * other forestry products.â 788.10 Section... products.” As used in the exemption, “other forestry products” mean plants of the forest and the natural... preparing such forestry products as well as transporting them to the mill, processing plant, railroad, or...

A preliminary study on the use of (10)Be in forensic radioecology of nuclear explosion sites.

PubMed

Whitehead, N E; Endo, S; Tanaka, K; Takatsuji, T; Hoshi, M; Fukutani, S; Ditchburn, R G; Zondervan, A

2008-02-01

Cosmogenic (10)Be, known for use in dating studies, unexpectedly is also produced in nuclear explosions with an atom yield almost comparable to (e.g.) (137)Cs. There are major production routes via (13)C(n, alpha)(10)Be, from carbon dioxide in the air and the organic explosives, possibly from other bomb components and to a minor extent from the direct fission reaction. Although the detailed bomb components are speculative, carbon was certainly present in the explosives and an order of magnitude calculation is possible. The (n, alpha) cross-section was determined by irradiating graphite in a nuclear reactor, and the resulting (10)Be estimated by Accelerator Mass Spectrometry (AMS) giving a cross-section of 34.5+/-0.7mb (6-9.3MeV), within error of previous work. (10)Be should have applications in forensic radioecology. Historical environmental samples from Hiroshima, and Semipalatinsk (Kazakhstan) showed two to threefold (10)Be excesses compared with the background cosmogenic levels. A sample from Lake Chagan (a Soviet nuclear cratering experiment) contained more (10)Be than previously reported soils. (10)Be may be useful for measuring the fast neutron dose near the Hiroshima bomb hypocenter at neutron energies double those previously available.

The Production "To Be or Not To Be? That Is the Question"

ERIC Educational Resources Information Center

Schroeter, Gillian

2010-01-01

Background: The high school production offers our students a creative way to develop their literacy, numeracy and social skills to mention a few. Why then do we permit anyone to teach the production and usually expect teachers to volunteer? Purpose: To do research into why the school production should be adopted as an integral part of our…

Meteoric 10Be in soil profiles - A global meta-analysis

USGS Publications Warehouse

Graly, Joseph A.; Bierman, Paul R.; Reusser, Lucas J.; Pavich, Milan J.

2010-01-01

In order to assess current understanding of meteoric 10Be dynamics and distribution in terrestrial soils, we assembled a database of all published meteoric 10Be soil depth profiles, including 104 profiles from 27 studies in globally diverse locations, collectively containing 679 individual measurements. This allows for the systematic comparison of meteoric 10Be concentration to other soil characteristics and the comparison of profile depth distributions between geologic settings. Percent clay, 9Be, and dithionite-citrate extracted Al positively correlate to meteoric 10Be in more than half of the soils where they were measured, but the lack of significant correlation in other soils suggests that no one soil factor controls meteoric 10Be distribution with depth. Dithionite-citrate extracted Fe and cation exchange capacity are only weakly correlated to meteoric 10Be. Percent organic carbon and pH are not significantly related to meteoric 10Be concentration when all data are complied.The compilation shows that meteoric 10Be concentration is seldom uniform with depth in a soil profile. In young or rapidly eroding soils, maximum meteoric 10Be concentrations are typically found in the uppermost 20 cm. In older, more slowly eroding soils, the highest meteoric 10Be concentrations are found at depth, usually between 50 and 200 cm. We find that the highest measured meteoric 10Be concentration in a soil profile is an important metric, as both the value and the depth of the maximum meteoric 10Be concentration correlate with the total measured meteoric 10Be inventory of the soil profile.In order to refine the use of meteoric 10Be as an estimator of soil erosion rate, we compare near-surface meteoric 10Be concentrations to total meteoric 10Be soil inventories. These trends are used to calibrate models of meteoric 10Be loss by soil erosion. Erosion rates calculated using this method vary based on the assumed depth and timing of erosional events and on the reference data selected.

What We are Learning from (and About) the 10 Plus Year MISR Aerosol Data Record

NASA Technical Reports Server (NTRS)

Kahn, Ralph A.

2010-01-01

Having a 10+ year data record from the Multi-angle Imaging SpectroRadiometer (MISR) significantly improves our opportunities to validate the retrieved aerosol optical depth (AOD) and especially particle microphysical property products. It also begins to raise the possibility of using the data to look for changes or even trends, at least on a regional basis. Further, we have had the opportunity to expand the database of wildfire smoke plume heights derived from the multiangle observations. This presentation will review the latest aerosol validation results and algorithm upgrades under consideration by the MISR team, and will summarize the current status of MISR global aerosol air mass type, and regional dust transport and smoke injection height products. The strengths and limitations of these data for constraining aerosol transport model simulations will receive special emphasis.

Production induced subsidence and seismicity in the Groningen gas field - can it be managed?

NASA Astrophysics Data System (ADS)

de Waal, J. A.; Muntendam-Bos, A. G.; Roest, J. P. A.

2015-11-01

Reliable prediction of the induced subsidence resulting from gas production is important for a near sea level country like the Netherlands. Without the protection of dunes, dikes and pumping, large parts of the country would be flooded. The predicted sea-level rise from global warming increases the challenge to design proper mitigation measures. Water management problems from gas production induced subsidence can be prevented if measures to counter its adverse effects are taken timely. This requires reliable subsidence predictions, which is a major challenge. Since the 1960's a number of large, multi-decade gas production projects were started in the Netherlands. Extensive, well-documented subsidence prediction and monitoring technologies were applied. Nevertheless predicted subsidence at the end of the Groningen field production period (for the centre of the bowl) went from 100 cm in 1971 to 77 cm in 1973 and then to 30 cm in 1977. In 1984 the prediction went up again to 65 cm, down to 36 cm in 1990 and then via 38 cm (1995) and 42 cm (2005) to 47 cm in 2010 and 49 cm in 2013. Such changes can have large implications for the planning of water management measures. Until 1991, when the first event was registered, production induced seismicity was not observed nor expected for the Groningen field. Thereafter the number of observed events rose from 5 to 10 per year during the 1990's to well over a hundred in 2013. The anticipated maximum likely magnitude rose from an initial value of less than 3.0 to a value of 3.3 in 1993 and then to 3.9 in 2006. The strongest tremor to date occurred near the village of Huizinge in August 2012. It had a magnitude of 3.6, caused significant damage and triggered the regulator into an independent investigation. Late 2012 it became clear that significantly larger magnitudes cannot be excluded and that values up to magnitude 5.0 cannot be ruled out. As a consequence the regulator advised early 2013 to lower Groningen gas production by as

40 CFR 716.10 - Studies to be reported.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.10 Studies to be reported. (a) In general, health and safety studies, as defined in § 716.3, on any substance or listed mixture listed in... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Studies to be reported. 716.10 Section...

40 CFR 716.10 - Studies to be reported.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.10 Studies to be reported. (a) In general, health and safety studies, as defined in § 716.3, on any substance or listed mixture listed in... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Studies to be reported. 716.10 Section...

40 CFR 716.10 - Studies to be reported.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.10 Studies to be reported. (a) In general, health and safety studies, as defined in § 716.3, on any substance or listed mixture listed in... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Studies to be reported. 716.10 Section...

40 CFR 716.10 - Studies to be reported.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Studies to be reported. 716.10 Section... ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.10 Studies to be reported. (a) In general, health and safety studies, as defined in § 716.3, on any substance or listed mixture listed in...

40 CFR 716.10 - Studies to be reported.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Studies to be reported. 716.10 Section... ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.10 Studies to be reported. (a) In general, health and safety studies, as defined in § 716.3, on any substance or listed mixture listed in...

Ten-year results from the long-term soil productivity study in aspen ecosystems of the northern Great Lakes region

Treesearch

Richard Voldseth; Brian J. Palik; John Elioff

2011-01-01

Impacts of organic matter removal and compaction on soil properties and productivity are reported from the first 10 years of the Long-Term Soil Productivity Study in Great Lakes aspen ecosystems. Organic matter removal treatments included main bole, total tree harvest, and total tree harvest with forest floor removal. Compaction treatments included minimal compaction,...

NASA Administrator Dan Goldin greets 10-year-old VIP.

NASA Technical Reports Server (NTRS)

2000-01-01

NASA Administrator Dan Goldin (center) talks to 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. In the background, between them, are Jonathan's mother, Penny; his grandfather, John Janocka; and his sister, Jaimie. At left is Mrs. Goldin. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

NASA Administrator Dan Goldin greets 10-year-old VIP.

NASA Technical Reports Server (NTRS)

2000-01-01

NASA Administrator Dan Goldin (center) presents a bag of special gifts to 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. In the background, between them, are Jonathan's mother, Penny; his grandfather, John Janocka; and his sister, Jaimie.. At left is Mrs. Goldin. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

NASA Administrator Dan Goldin greets 10-year-old VIP.

NASA Technical Reports Server (NTRS)

2000-01-01

NASA Administrator Dan Goldin (center) greets 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. In the background, between them, are Jonathan's mother, Penny; his grandfather, John Janocka; and his sister, Jaimie.. At left is Mrs. Goldin. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

Mental and somatic health in a non-clinical sample 10 years after a diagnosis of encopresis.

PubMed

Hultén, Ib; Jonsson, Jakob; Jonsson, Carl-Otto

2005-12-01

The aim of this study was to assess the relation between the diagnosis of encopresis at 8 and 10 years of age, and mental and somatic health 10 years later. The importance of type of encopresis (primary or secondary) at 8 years was also studied. Subjects were a non-clinical encopretic sample (N=73) and control subjects (N=75) [2]. Seven assessment variables from conscription surveys provided information about mental and somatic health status at 18 years of age. Former encopretics (n=66) did not differ significantly from the controls (n=67) at 18 years of age, although there were consistent, small negative differences. The boys who at 10 years of age had still been encopretic did not differ significantly at 18 years of age from the boys who at 10 years had recovered from encopresis, and the signs indicating the small differences varied. For former primary and secondary encopretic boys, there were two significant differences, the men in the secondary group being more often exempted from conscription than the primary group and the control cases. The results indicate that boys with non-clinical encopresis show only small, if any, mental and somatic disturbances at the beginning of adulthood. Comprehensive investigations of encopretic patients are recommended as important clinical problems, in addition to encopresis, might be present.

Landscape disequilibrium on 1000-10,000 year scales Marsyandi River, Nepal, central Himalaya

NASA Astrophysics Data System (ADS)

Pratt-Sitaula, Beth; Burbank, Douglas W.; Heimsath, Arjun; Ojha, Tank

2004-03-01

In an actively deforming orogen, maintenance of a topographic steady state requires that hillslope erosion, river incision, and rock uplift rates are balanced over timescales of 10 5-10 7 years. Over shorter times, <10 5 years, hillslope erosion and bedrock river incision rates fluctuate with changes in climate. On 10 4-year timescales, the Marsyandi River in the central Nepal Himalaya has oscillated between bedrock incision and valley alluviation in response to changes in monsoon intensity and sediment flux. Stratigraphy and 14C ages of fill terrace deposits reveal a major alluviation, coincident with a monsoonal maximum, ca. 50-35 ky BP. Cosmogenic 10Be and 26Al exposure ages define an alluviation and reincision event ca. 9-6 ky BP, also at a time of strong South Asian monsoons. The terrace deposits that line the Lesser Himalayan channel are largely composed of debris flows which originate in the Greater Himalayan rocks up to 40 km away. The terrace sequences contain many cubic kilometers of sediment, but probably represent only 2-8% of the sediments which flushed through the Marsyandi during the accumulation period. At ˜10 4-year timescales, maximum bedrock incision rates are ˜7 mm/year in the Greater Himalaya and ˜1.5 mm/year in the Lesser Himalayan Mahabarat Range. We propose a model in which river channel erosion is temporally out-of-phase with hillslope erosion. Increased monsoonal precipitation causes an increase in hillslope-derived sediment that overwhelms the transport capacity of the river. The resulting aggradation protects the bedrock channel from erosion, allowing the river gradient to steepen as rock uplift continues. When the alluvium is later removed and the bedrock channel re-exposed, bedrock incision rates probably accelerate beyond the long-term mean as the river gradient adjusts downward toward a more "equilibrium" profile. Efforts to document dynamic equilibrium in active orogens require quantification of rates over time intervals

GCR flux reconstruction during the last three centuries validated by the Ti-44 in meteorites and Be-10 in ice

NASA Astrophysics Data System (ADS)

Cini Castagnoli, G.; Cane, D.; Taricco, C.; Bhandari, N.

2003-04-01

In a previous work [1] we deduced that during prolonged minima of solar activity since 1700 the galactic cosmic rays (GCR) flux was much higher (˜2 times) respect to what we can infer from GCR modulation deduced solely by the Sunspot Number series. This flux was higher respect to what we observe in the last decades by Neutron Monitor or balloon and spacecraft-borne detectors and confirmed by the three fresh-fall meteorites that we have measured during solar cycle 22. Recently we have deduced the GCR annual mean spectra for the last 300 years [2], starting from the open solar magnetic flux proposed by Solanki et al. [3]. Utilizing the GCR flux we have calculated the 44Ti (T1/2 = 59.2 y) activity in meteorites taking into account the cross sections for its production from the main target element Fe and Ni. We compare the calculated activity with our measurements of the cosmogenic 44Ti in different chondrites fell in the period 1810-1997. The results are in close agreement both in phase and amplitude. The same procedure has been adopted for calculating the production rate of 10Be in atmosphere. Normalizing to the concentration in ice in the solar cycles 20 and 21 we obtain a good agreement with the 10Be profile in Dye3 core [4]. These results demonstrate that our inference of the GCR flux in the past 300 years is reliable. [1] Bonino G., Cini Castagnoli G., Bhandari N., Taricco C., textit {Science}, 270, 1648, 1995 [2] Bonino G., Cini Castagnoli G., Cane D., Taricco C. and Bhandari N., textit {Proc. XXVII Intern. Cosmic Ray Conf.} (Hamburg, 2001) 3769-3772. [3] Solanki S.K., Schüssler M. and Fligge M.,Nature, 408, 445, 2000 [4] Beer J. et al., private communication

Effect of cooking and in vitro digestion on the stability of co-enzyme Q10 in processed meat products.

PubMed

Tobin, Brian D; O'Sullivan, Maurice G; Hamill, Ruth; Kerry, Joseph P

2014-05-01

The use of CoQ10 fortification in the production of a functional food has been demonstrated in the past but primarily for dairy products. This study aimed to determine the bio-accessibility of CoQ10 in processed meat products, beef patties and pork breakfast sausages, fortified with CoQ10. Both the patties and sausages were fortified with a micellarized form of CoQ10 to enhance solubility to a concentration of 1mg/g of sample (NovaSolQ®). An assay was developed combining in vitro digestion and HPLC analysis to quantify the CoQ10 present in fortified products (100mg/g). The cooking retention level of CoQ10 in the products was found to be 74±1.42% for patties and 79.69±0.75% for sausages. The digestibility for both products ranged between 93% and 95%, sausages did have a higher digestibility level than patties but this was not found to be significant (P<0.01). Copyright © 2013 Elsevier Ltd. All rights reserved.

21 CFR 1040.10 - Laser products.

Code of Federal Regulations, 2012 CFR

2012-04-01

... laser(s). (13) Demonstration laser product means any laser product manufactured, designed, intended, or..., designed, intended, or promoted for such purposes, even though they may be used for those purposes or are... laser product which is a medical device as defined in 21 U.S.C. 321(h) and is manufactured, designed...

21 CFR 1040.10 - Laser products.

Code of Federal Regulations, 2014 CFR

2014-04-01

... laser(s). (13) Demonstration laser product means any laser product manufactured, designed, intended, or..., designed, intended, or promoted for such purposes, even though they may be used for those purposes or are... laser product which is a medical device as defined in 21 U.S.C. 321(h) and is manufactured, designed...

21 CFR 1040.10 - Laser products.

Code of Federal Regulations, 2013 CFR

2013-04-01

... laser(s). (13) Demonstration laser product means any laser product manufactured, designed, intended, or..., designed, intended, or promoted for such purposes, even though they may be used for those purposes or are... laser product which is a medical device as defined in 21 U.S.C. 321(h) and is manufactured, designed...

Prevalence of Irritable Bowel Syndrome and Chronic Fatigue 10 Years After Giardia Infection.

PubMed

Litleskare, Sverre; Rortveit, Guri; Eide, Geir Egil; Hanevik, Kurt; Langeland, Nina; Wensaas, Knut-Arne

2018-03-06

Irritable bowel syndrome (IBS) is a complication that can follow gastrointestinal infection, but it is not clear if patients also develop chronic fatigue. We investigated the prevalence and odds ratio of IBS and chronic fatigue 10 years after an outbreak of Giardia lamblia, compared with a control cohort, and changes in prevalence over time. We performed a prospective follow-up study of 1252 laboratory-confirmed cases of giardiasis (exposed), which developed in Bergen, Norway in 2004. Statistics Norway provided us with information from 2504 unexposed individuals from Bergen, matched by age and sex (controls). Questionnaires were mailed to participants 3, 6, and 10 years after the outbreak. Results from the 3- and 6-year follow-up analyses have been published previously. We report the 10-year data and changes in prevalence among time points, determined by logistic regression using generalized estimating equations. The prevalence of IBS 10 years after the outbreak was 43% (n = 248) among 576 exposed individuals and 14% (n = 94) among 685 controls (adjusted odds ratio for development of IBS in exposed individuals, 4.74; 95% CI, 3.61-6.23). At this time point, the prevalence of chronic fatigue was 26% (n = 153) among 587 exposed individuals and 11% (n = 73) among 692 controls (adjusted odds ratio, 3.01; 95% CI, 2.22-4.08). The prevalence of IBS among exposed persons did not change significantly from 6 years after infection (40%) to 10 years after infection (43%; adjusted odds ratio for the change 1.03; 95% CI, 0.87-1.22). However, the prevalence of chronic fatigue decreased from 31% at 6 years after infection to 26% at 10 years after infection (adjusted odds ratio for the change 0.74; 95% CI, 0.61-0.90). The prevalence of IBS did not change significantly from 6 years after an outbreak of Giardia lamblia infection in Norway to 10 years after. However, the prevalence of chronic fatigue decreased significantly from 6 to 10 years afterward. IBS and chronic fatigue were

Process and product in writing--a methodological contribution to the assessment of written narratives in 8-12-year-old Swedish children using ScriptLog.

PubMed

Asker-Arnason, Lena; Wengelin, Asa; Sahlén, Birgitta

2008-01-01

Twenty-seven children, with typical language development (TLD), 8-10 years old and 10-12 years old, were assessed with keystroke-logging in order to investigate their narrative writing. Measures of the writing process and the written product were used. One purpose was to explore how children produce written narratives in on-line production, and to relate the writing process to the written product. The results showed that those children who produced the final text faster, also wrote stories that comprised of more words. In the group of older children, children with better narrative ability used less pause time than those with worse ability, and the girls were faster writers than the boys. We believe that keystroke-logging gives valuable information for the assessment of young children's writing and that it is a potentially valid assessment tool for children from about 10 years of age.

Interleukin-10-1082 promoter polymorphism in association with cytokine production and sepsis susceptibility.

PubMed

Stanilova, Spaska A; Miteva, Lyuba D; Karakolev, Zhivko T; Stefanov, Chavdar S

2006-02-01

To investigate the -1082 (A/G) polymorphism in the promoter of the IL-10 gene in terms of IL-10 production from stimulated peripheral blood mononuclear cells (PBMC) and to evaluate the relationship of this polymorphism with susceptibility to severe sepsis and the outcome of the disease. Case-control study. Research laboratory of Molecular Biology and Immunology and University Hospital ICU, Faculty of Medicine, Trakia University. A total of 53 healthy volunteers and 33 patients in ICU meeting the criteria for severe sepsis were included. The amplification refractory mutation system PCR was used for IL-10-1082 polymorphism detection. Isolated PBMC were stimulated with either C3-binding glycoprotein (C3bgp), lipopolysaccharide (LPS), phytohemagglutinin (PHA),or pokeweed mitogen (PWM). IL-10 production was measured in culture supernatants. The AA genotype was associated with lower IL-10 production in LPS-, PHA- or PWM-stimulated healthy PBMC. Patients with severe sepsis had significant elevation of A allele, compared with healthy controls (74.2% vs 52.8%; p=0.0062). Carriage of at least one copy of IL-10-1082 G allele in sepsis patients and in healthy controls resulted in a statistically significant increase in IL-10 production from stimulated PBMC. Surviving sepsis patients had a significant decrease of IL-10-1082 allele G frequency, compared with controls (17% vs 47.2%; p=0.012). An association between increased IL-10 production and poor outcome from sepsis was observed. The A allele of the -1082 polymorphism in the interleukin-10 gene promoter is associated with sepsis susceptibility, whereas G allele is associated with higher stimulated interleukin-10 production and increased mortality in severe sepsis.

Association of chronic insomnia symptoms and recurrent extreme sleep duration over 10 years with well-being in older adults: a cohort study

PubMed Central

Abell, Jessica G; Shipley, Martin J; Ferrie, Jane E; Kivimäki, Mika; Kumari, Meena

2016-01-01

Objectives The extent to which aspects of sleep affect well-being in the long-term remains unclear. This longitudinal study examines the association between chronic insomnia symptoms, recurrent sleep duration and well-being at older ages. Setting A prospective cohort of UK civil servants (the Whitehall II study). Participants 4491 women and men (25.2% women) with sleep measured 3 times over 10 years and well-being once at age 55–79 years. Insomnia symptoms and sleep duration were assessed through self-reports in 1997–1999, 2003–2004 and 2007–2009. Primary outcome measures Indicators of well-being, measured in 2007–2009, were the Control, Autonomy, Self-realisation and Pleasure measure (CASP-19) of overall well-being (range 0–57) and the physical and mental well-being component scores (range 0–100) of the Short Form Health Survey (SF-36). Results In maximally adjusted analyses, chronic insomnia symptoms were associated with poorer overall well-being (difference between insomnia at 3 assessments vs none −7.0 (SE=0.4) p<0.001), mental well-being (difference −6.9 (SE=0.4), p<0.001) and physical well-being (difference −2.8 (SE=0.4), p<0.001) independently of the other sleep measures. There was a suggestion of a dose–response pattern in these associations. In addition, recurrent short sleep (difference between ≤5 h sleep reported at 3 assessments vs none −1.7 (SE=0.7), p<0.05) and recurrent long sleep (difference between >9 h reported at 2 or 3 assessments vs none −3.5 (SE=0.9), p<0.001) were associated with poorer physical well-being. Conclusions We conclude that in older people, chronic insomnia symptoms are negatively associated with all aspects of well-being, whereas recurrent long and short sleep is only associated with reduced physical well-being. PMID:26832429

Maxillary Three-Implant Overdentures Opposing Mandibular Two-Implant Overdentures: 10-Year Surgical Outcomes of a Randomized Controlled Trial.

PubMed

Ma, Sunyoung; Tawse-Smith, Andrew; De Silva, Rohana K; Atieh, Momen A; Alsabeeha, Nabeel H M; Payne, Alan G T

2016-06-01

The surgical placement of four maxillary implants for overdentures may not be obligatory when opposing mandibular two-implant overdentures. To determine 10-year surgical outcomes and implant success of three narrow diameter implants in edentulous maxillae with conventional loading. Forty participants with mandibular two-implant overdentures were randomly allocated for surgery for maxillary overdentures. Using osteotomes, three implants of similar systems were placed with a one-stage procedure and 12-week loading with splinted and unsplinted prosthodontic designs. Marginal bone and stability measurements were done at surgery, 12 weeks, 1-, 2-, 5-, 7-, 10 years. One hundred seventeen implants were placed in 39 participants, with 35 being seen at 1 year; 29 at 2 years; 28 at 5 years; 26 at 7 years; and 23 (59%) at 10 years. Marginal bone loss was 1.35 mm between surgery and 12 weeks; 0.36 mm between 12 weeks and 1 year; 0.48 mm between 1 and 5 years; and 0.22 mm between 5 and 10 years. Implant stability quotients were 56.05, 57.54, 60.88, 58.80, 61.17 at surgery, 12 weeks, 1 year, 5 years, and 10 years. Four-field tables by implant showed success rates of 82% at 1 year; 69.2% at 2 years; 66.7% at 5 years; 61.5% at 7 years; 51.3% at 10 years. Data showed no differences between surgical technique, systems, or prosthodontic designs. Surgical placement with osteotomes of three narrow diameter implants for maxillary overdentures, opposing mandibular two-implant overdentures, is an acceptable approach, subject to strict patient selection. Implant success is independent of prosthodontic design. © 2015 Wiley Periodicals, Inc.

Synthesis of 10-years of Ecohydrologic studies on Turkey Creek watershed

Treesearch

Devendra Amatya; Timothy Callahan; Carl Trettin

2016-01-01

Since the establishment of a collaborative study 10 years ago, research on the third-order, 5240 ha forested Turkey Creek watershed in South Carolina’s coastal plain has advanced the understanding of rainfall-runoff relationships, stream hydrograph characteristics, and water table dynamics for dominant soil types. Surface water dynamics were shown to be regulated...

Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials.

PubMed

Darby, S; McGale, P; Correa, C; Taylor, C; Arriagada, R; Clarke, M; Cutter, D; Davies, C; Ewertz, M; Godwin, J; Gray, R; Pierce, L; Whelan, T; Wang, Y; Peto, R

2011-11-12

cancer death from 51·3% to 42·8% (absolute reduction 8·5%, 1·8-15·2, 2p=0·01). Overall, about one breast cancer death was avoided by year 15 for every four recurrences avoided by year 10, and the mortality reduction did not differ significantly from this overall relationship in any of the three prediction categories for pN0 disease or for pN+ disease. After breast-conserving surgery, radiotherapy to the conserved breast halves the rate at which the disease recurs and reduces the breast cancer death rate by about a sixth. These proportional benefits vary little between different groups of women. By contrast, the absolute benefits from radiotherapy vary substantially according to the characteristics of the patient and they can be predicted at the time when treatment decisions need to be made. Cancer Research UK, British Heart Foundation, and UK Medical Research Council. Copyright © 2011 Elsevier Ltd. All rights reserved.

Frequency of Cushing's syndrome due to ACTH-secreting adrenal medullary lesions: a retrospective study over 10 years from a single center.

PubMed

Falhammar, Henrik; Calissendorff, Jan; Höybye, Charlotte

2017-01-01

Cushing's syndrome due to ectopic adrenocorticotropic hormone production from adrenal medullary lesions has occasionally been described. We retrospectively reviewed all 164 cases of Cushing's syndrome and 77 cases of pheochromocytomas during 10 years. Of all cases with Cushing's syndrome, only two cases (1.2 %) were due to ectopic adrenocorticotropic hormone production from adrenal medullary lesions (one case of pheochromocytoma and one case of adrenal medullary hyperplasia). Of all pheochromocytomas only the above-mentioned case (1.3 %) also gave rise to an ectopic adrenocorticotropic hormone syndrome. The clinical presentation of adrenocorticotropic hormone-secreting pheochromocytoma and adrenal medullary hyperplasia can be anything from mild to dramatic. These are rare conditions important to bear in mind in the workup of a patient with Cushing's syndrome or with pheochromocytoma. The identification of ectopic adrenocorticotropic hormone secretion from adrenal medullary lesions can be life-saving.

Changes in Perceptions of Studying for the GCSE among Year 10 and Year 11 Pupils

ERIC Educational Resources Information Center

Rogers, Lynne; Hallam, Susan

2010-01-01

This research aimed to explore whether pupils' perceptions of studying for the General Certificate of Secondary Education (GCSE) altered during the two-year period of study of this qualification. Six hundred and forty four pupils from eight schools in outer London completed a self-report questionnaire on two occasions, once in Year 10 and once in…

Prediction of transition from common adolescent bipolar experiences to bipolar disorder: 10-year study.

PubMed

Tijssen, Marijn J A; van Os, Jim; Wittchen, Hans-Ulrich; Lieb, Roselind; Beesdo, Katja; Mengelers, Ron; Wichers, Marieke

2010-02-01

Although (hypo)manic symptoms are common in adolescence, transition to adult bipolar disorder is infrequent. To examine whether the risk of transition to bipolar disorder is conditional on the extent of persistence of subthreshold affective phenotypes. In a 10-year prospective community cohort study of 3021 adolescents and young adults, the association between persistence of affective symptoms over 3 years and the 10-year clinical outcomes of incident DSM-IV (hypo)manic episodes and incident use of mental healthcare was assessed. Transition to clinical outcome was associated with persistence of symptoms in a dose-dependent manner. Around 30-40% of clinical outcomes could be traced to prior persistence of affective symptoms. In a substantial proportion of individuals, onset of clinical bipolar disorder may be seen as the poor outcome of a developmentally common and usually transitory non-clinical bipolar phenotype.

19 CFR 10.133 - Conditions required to be met.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Conditions required to be met. 10.133 Section 10.133 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... Duty Dependent Upon Actual Use § 10.133 Conditions required to be met. When the tariff classification...

19 CFR 10.133 - Conditions required to be met.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Conditions required to be met. 10.133 Section 10.133 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... Duty Dependent Upon Actual Use § 10.133 Conditions required to be met. When the tariff classification...

Optimal parameters for marking upper blepharoplasty incisions: a 10-year experience.

PubMed

Halvorson, Eric G; Husni, Nicholas R; Pandya, Sonal N; Seckel, Brooke R

2006-05-01

Although a variety of techniques for upper blepharoplasty have been described, few studies illustrate and clinically evaluate a system for marking incisions. Presented is a 10-year experience using a specific method for marking upper blepharoplasty incisions that consistently yielded excellent esthetic results. All upper blepharoplasties performed by the senior author between April, 1994 and April, 2004 were reviewed. Markings were designed to end the medial incision 6 mm from the angular vein, end the lateral incision 12 mm from the palpebral fissure, and to extend the incisions superiorly at 45 degrees. Over 10 years, 476 patients underwent cosmetic upper blepharoplasty. There were 22 (4.6%) revisions. Eighteen (3.8%) were performed in clinic using CO2 laser, and 4 (0.8%) patients required surgical revision. Patient satisfaction was high, and no scars were visible outside the brow. Excellent outcomes can be expected using this simple, reproducible, and widely applicable system for marking upper blepharoplasty incisions.

"JPBI" 10 Years Later: Trends in Research Studies

ERIC Educational Resources Information Center

O'Dell, Sean M.; Vilardo, Brigid A.; Kern, Lee; Kokina, Anastasia; Ash, Allison N.; Seymour, Kimberly J.; Castrantas, Lauren M.; Kollar, Rachel B.; Wagner, Andrea M.; Bartholomew, Audrey; Thomas, Lisa B.

2011-01-01

In 2008, the "Journal of Positive Behavior Interventions" ("JPBI") celebrated 10 years in publication. As the flagship journal of positive behavior support (PBS), it is important to periodically examine the research published in "JPBI" to determine whether it reflects the basic principles of PBS, to explore the ways in which PBS is being…

Year-round behaviour of soil microarthropod communities under plant protection product application.

PubMed

Vaj, Claudia; Van Gestel, Cornelis A M; Vighi, Marco

2014-07-01

The use of plant protection products (PPPs) in agro-environments can lead to undesired exposure of non-target organisms in non-target compartments. A year-round field survey was conducted in a vineyard in Northern Italy, for monitoring the changes in the structure of soil microarthropod communities under the application of PPPs, focusing on springtails and mites, both inside and 4 and 10 m outside the vineyard. Exposure to PPPs was estimated as time-weighted average soil concentrations. The fluctuations in the abundances of the different organisms after the application of PPPs, especially insecticides, were recorded. A recovery in abundances was observed at the end of the productive season outside the field and at the beginning of the next spring within the vineyard. Using multivariate statistical tools, the behaviour of each taxon in relation to the stressors was assessed. Some organisms were affected by the stressors, while others were favoured because of low vulnerability to PPPs and the indirect effect of the absence of other taxa. The principal response curves (PRC) method was the most sensitive tool for assessing PPP effects on soil arthropod communities. Strong differences were evident in the structure of the communities inside and outside the vineyard, with the communities sampled 4 and 10 m outside the vineyard being fairly similar, the latter considered as control. The role of physical stressors on community composition is recognised. However, chemical stressors, and in particular PPP exposure seemed to have larger effects on structural and functional characteristics of soil arthropod communities than physical stressors.

10 CFR 719.10 - What information must be included in the legal management plan?

Code of Federal Regulations, 2011 CFR

2011-01-01

... be ensured; and, (6) The contractor's corporate approach to legal decision making. ... 10 Energy 4 2011-01-01 2011-01-01 false What information must be included in the legal management... Management Plan § 719.10 What information must be included in the legal management plan? The legal management...

Adherence to Dietary Guidelines and Successful Aging Over 10 Years.

PubMed

Gopinath, Bamini; Russell, Joanna; Kifley, Annette; Flood, Victoria M; Mitchell, Paul

2016-03-01

We aimed to prospectively examine the relationship between overall diet quality (reflecting adherence to dietary guidelines) and successful aging in a population-based cohort of older adults. In this population-based cohort study, we analyzed 10-year follow-up data from 1,609 adults aged 49 years and older, who were free of cancer, coronary artery disease, and stroke at the baseline and who had complete dietary data. Dietary data were collected using a semiquantitative food frequency questionnaire. Total diet scores (TDS) were allocated for intake of selected food groups and nutrients for each participant as described in the national dietary guidelines. Higher scores indicated closer adherence to dietary guidelines. Successful aging was defined as the absence of disability, depressive symptoms, cognitive impairment, respiratory symptoms, and chronic diseases (cancer, coronary artery disease, and stroke). At 10-year follow-up, 610 (37.9%) participants had died and 249 (15.5%) participants aged successfully. After multivariable adjustment, each 1-unit increase in TDS at baseline was associated with a 8% increased odds of successful aging 10 years later, odds ratio 1.08 (95% confidence interval 1.00-1.15). Participants in the highest (high adherence to dietary guidelines) versus lowest quartile (poor adherence to guidelines) of TDS at baseline had 58% higher odds of successful aging after 10 years, odds ratio 1.58 (95% confidence interval 1.02-2.46). Greater compliance with recommended national dietary guidelines (higher diet quality) was associated with an increased likelihood of successful aging, as determined through a multidomain approach. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Avian response to bottomland hardwood reforestation: the first 10 years

USGS Publications Warehouse

Twedt, D.J.; Wilson, R.R.; Henne-Kerr, J.L.; Grosshuesch, D.A.

2002-01-01

Bttomland hardwood forests were planted on agricultural fields in Mississippi and Louisiana using either predominantly Quercus species (oaks) or Populus deltoides (eastern cottonwood). We assessed avian colonization of these reforested sites between 2 and 10 years after planting. Rapid vertical growth of cottonwoods (circa 2 - 3 m / yr) resulted in sites with forest structure that supported greater species richness of breeding birds, increased Shannon diversity indices, and supported greater territory densities than on sites planted with slower-growing oak species. Grassland birds (Spiza americana [Dickcissel], and Sturnella magna [Eastern Meadowlark]) were indicative of species breeding on oak-dominated reforestation # 10 years old. Agelaius phoeniceus (Red-winged Blackbird) and Colinus virginianus (Northern Bobwhite) characterized cottonwood reforestation # 4 years old, whereas 14 species of shrub-scrub birds (e.g., Passerina cyanea [Indigo Bunting]) and early-successional forest birds (e.g., Vireo gilvus [Warbling Vireo]) typified cottonwood reforestation 5 to 9 years after planting. Rates of daily nest survival did not differ between reforestation strategies. Nest parasitism increased markedly in older cottonwood stands, but was overwhelmed by predation as a cause of nest failure. Based on Partners in Flight prioritization scores and territory densities, the value of cottonwood reforestation for avian conservation was significantly greater than that of oak reforestation during their first 10 years. Because of benefits conferred on breeding birds, we recommend reforestation of bottomland hardwoods include a high proportion of fast-growing, early successional species such as cottonwood.

[Lessons from 10 years of the Advanced Glaucoma Intervention Study (AGIS)].

PubMed

Dietlein, T S

2005-03-01

The 10-year results of the AGIS have revealed different outcomes of therapeutic strategies depending on ethnic factors, but also different success rates of trabeculectomy depending on age, preoperative intraocular pressure, and presence of diabetes or postoperative complications. Conclusions from the study may be limited by the fact that medical options and surgical strategies in glaucoma treatment have obviously changed during the last decade.

Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women.

PubMed

Sinaki, M; Itoi, E; Wahner, H W; Wollan, P; Gelzcer, R; Mullan, B P; Collins, D A; Hodgson, S F

2002-06-01

The long-term protective effect of stronger back muscles on the spine was determined in 50 healthy white postmenopausal women, aged 58-75 years, 8 years after they had completed a 2 year randomized, controlled trial. Twenty-seven subjects had performed progressive, resistive back-strengthening exercises for 2 years and 23 had served as controls. Bone mineral density, spine radiographs, back extensor strength, biochemical marker values, and level of physical activity were obtained for all subjects at baseline, 2 years, and 10 years. Mean back extensor strength (BES) in the back-exercise (BE) group was 39.4 kg at baseline, 66.8 kg at 2 years (after 2 years of prescribed exercises), and 32.9 kg at 10 years (8 years after cessation of the prescribed exercises). Mean BES in the control (C) group was 36.9 kg at baseline, 49.0 kg at 2 years, and 26.9 kg at 10 years. The difference between the two groups was still statistically significant at 10 year follow-up (p = 0.001). The difference in bone mineral density, which was not significant between the two groups at baseline and 2 year follow-up, was significant at 10 year follow-up (p = 0.0004). The incidence of vertebral compression fracture was 14 fractures in 322 vertebral bodies examined (4.3%) in the C group and 6 fractures in 378 vertebral bodies examined (1.6%) in the BE group (chi-square test, p = 0.0290). The relative risk for compression fracture was 2.7 times greater in the C group than in the BE group. To our knowledge, this is the first study reported in the literature demonstrating the long-term effect of strong back muscles on the reduction of vertebral fractures in estrogen-deficient women.

10 CFR 490.8 - Replacement fuel production goal.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 3 2014-01-01 2014-01-01 false Replacement fuel production goal. 490.8 Section 490.8 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM General... sufficient to replace, on an energy equivalent basis, at least 30 percent of motor fuel consumption in the...

10 CFR 490.8 - Replacement fuel production goal.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 3 2013-01-01 2013-01-01 false Replacement fuel production goal. 490.8 Section 490.8 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM General... sufficient to replace, on an energy equivalent basis, at least 30 percent of motor fuel consumption in the...

10 CFR 490.8 - Replacement fuel production goal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Replacement fuel production goal. 490.8 Section 490.8 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM General... sufficient to replace, on an energy equivalent basis, at least 30 percent of motor fuel consumption in the...

10 CFR 490.8 - Replacement fuel production goal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 3 2011-01-01 2011-01-01 false Replacement fuel production goal. 490.8 Section 490.8 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM General... sufficient to replace, on an energy equivalent basis, at least 30 percent of motor fuel consumption in the...

10 CFR 490.8 - Replacement fuel production goal.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 3 2012-01-01 2012-01-01 false Replacement fuel production goal. 490.8 Section 490.8 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM General... sufficient to replace, on an energy equivalent basis, at least 30 percent of motor fuel consumption in the...

Predictors for Employment Status in People With Multiple Sclerosis: A 10-Year Longitudinal Observational Study.

PubMed

Forslin, Mia; Fink, Katharina; Hammar, Ulf; von Koch, Lena; Johansson, Sverker

2018-01-31

To identify predictors for employment status after 10 years in a cohort of people with multiple sclerosis (MS), with the aim to increase knowledge concerning factors present at an early stage that are important for working life and work-life balance. A 10-year longitudinal observational cohort study. University hospital. A consecutive sample of people with MS (N=154) of working age were included at baseline, of which a total of 116 people participated in the 10-year follow-up; 27 people declined participation and 11 were deceased. Not applicable. Baseline data on personal factors and functioning were used as independent variables. Employment status 10 years after baseline, categorized as full-time work, part-time work, and no work, was used as the dependent variable. A generalized ordinal logistic regression was used to analyze the predictive value of the independent variables. Predictors for full- or part-time work after 10 years were young age (P=.002), low perceived physical impact of MS (P=.02), fatigue (P=.03), full-time work (P=.001), and high frequency of social/lifestyle activities (P=.001) at baseline. Low perceived physical impact of MS (P=.02) at baseline also predicted full-time work after 10 years. This study underlines the complexity of working life for people with MS, and indicates that it may be valuable to give more attention to the balance between working and private life, both in clinical practice and future research, to achieve a sustainable working life over time. Copyright © 2018 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

The HLA-matching effect in different cohorts of kidney transplant recipients: 10 years later.

PubMed

Sasaki, Nori; Idica, Adam

2010-01-01

% lower for the 5 or 6 mismatch cases. Utilizing the transplant cases of 2005 through 2009, we projected their 10-year graft survivals for year 2020. The 10-year graft survival for 0 ABDR mismatched patients is expected to be over 85% and nearly 70% for 5 or 6 ABDR mismatched patients. The general upward trend of graft survival we have observed in the last 10 years has been dependent upon the development of novel transplant protocols and use of novel immunomodulatory reagents. This trend is likely to continue given the promise of new drugs and personalized healthcare. The decreasing range of the differences in the 10-year graft survival between best matched and worst matched HLA groups is also likely to continue. One interesting trend that is clearly evident is the increasing difference between the best and worst HLA-matching in terms of the associated graft half-life. The positive HLA-matching effect on long-term graft survival is clearly evident and should be taken into consideration for all kidney transplants.

An Analysis of the Development of Auricular Acupuncture in China in the Past 10 Years.

PubMed

Zhao, Baixiao; Meng, Xiaonan; Sun, Jie

2018-06-01

Objective: The aim of this research was to analyze recent developments of auricular acupuncture in China during the past 10 years, from 2007 to 2016. Methods: The articles evaluated related to auricular acupuncture studies published in the last 10 years, from 2007 to 2016. The articles were retrieved from the China National Knowledge Infrastructure (CNKI) full-text journal database and from Tsinghua Tongfang, the Chinese Knowledge net. The history of auricular acupuncture, the overall status of the research, and the current use of standardization were analyzed and summarized. Results: The literature research of auricular acupuncture in China revealed that there was a high frequency of publications over the last 10 years. Conclusions: Development of more auricular acupuncture research teams, improvement of the level and quality of the research, and basic and clinical research investigations on auricular acupuncture in China have demonstrated continuous improvement in the past 10 years. It is hoped that this research will continue into the future, offering greater contributions to the development of auricular acupuncture for the health care of human beings.

Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor

PubMed Central

Rahim, Sheikh Showkat; Khan, Nooruddin; Boddupalli, Chandra Sekhar; Hasnain, Seyed E; Mukhopadhyay, Sangita

2005-01-01

Interleukin-10 (IL-10) is known to inhibit IL-12 production in macrophages primarily at the transcriptional level with the involvement of p50 and p65 nuclear factor-κB (NF-κB). We demonstrate that the c-rel transcription factor also plays a major role in IL-10-mediated IL-12 suppression. Treatment of macrophages with recombinant IL-10 inhibited nuclear c-rel levels, whereas addition of neutralizing anti-IL-10 antibody up-regulated both nuclear c-rel levels and IL-12 production by macrophages. Decreased nuclear c-rel was associated with a reduction in phosphorylation of inhibitory kappa B alpha (IκBα) in the cytoplasm, indicating that IL-10 prevents degradation of IκBα and the subsequent translocation of c-rel into the nucleus. Treatment with leptomycin B, a known inhibitor of c-rel at a concentration of 10 nm, when used with anti-IL-10 antibody, resulted in reduced expression of IL-12. In a complementary experiment, in vitro transient expression of p65 NF-κB could not rescue the inhibitory effect of IL-10 on IL-12 production, suggesting that NF-κB alone was not sufficient to restore IL-12 production during IL-10 treatment. However, over-expression of c-rel resulted in IL-12 restoration upon stimulation with lipopolysaccharide plus interferon-γ during IL-10 treatment. Our studies highlight the involvement of c-rel in IL-10-mediated IL-12 regulation. PMID:15720433

Heterotrophic bacterioplankton in the Arabian Sea:. Basinwide response to year-round high primary productivity

NASA Astrophysics Data System (ADS)

Ducklow, H. W.; Smith, D. C.; Campbell, L.; Landry, M. R.; Quinby, H. L.; Steward, G. F.; Azam, F.

Heterotrophic bacterial abundance and productivity were measured during five and four cruises, respectively, in the northwest Arabian Sea as part of the US JGOFS Process Study, which provided a new view of seasonal bacterial dynamics in that part of the basin influenced by monsoonal forcing. In this paper, surface layer data are used to address two questions concerning the influence of the monsoon cycle on bacterial dynamics: (1) Is there a bacterial bloom in the SW Monsoon? and (2) Is bacterial production low during the oligotrophic Spring Intermonsoon? An extensive comparison of epifluorescence microscopy and flow cytometry, unprecedented at this scale, detected essentially the same heterotrophic bacterial populations and distributions, with some between-cruise differences. Use of the two methods allowed us to extend our observations in space and time. Bacterial productivity, both in the surface layer and integrated over the euphotic zone, was elevated less than 2-fold during the Southwest Monsoon. Levels of bacterial abundance and production were low during the Northeast Monsoon, then increased in March during the Spring Intermonsoon. There was some stimulation of abundance or production inshore in response to coastal upwelling. In general, the basin was enriched in bacterial biomass >5×10 8 cells l -1 throughout the year, relative to other tropical regimes, presumably in response to overall high PP and DOC levels. Seasonally uniform DOC levels may be regulated in part by intense bacterial utilization rates, but also reflect seasonal consistency in PP.

Is maternal education level associated with diet in 10-year-old children?

PubMed

Cribb, Victoria L; Jones, Louise R; Rogers, Imogen S; Ness, Andrew R; Emmett, Pauline M

2011-11-01

To examine the associations between maternal education level and diet in 10-year-old children. Three-day diet diaries (child completed with parental help) were collected. Height and weight were measured in research clinics. Maternal education level was derived from a questionnaire completed during pregnancy and classified into low, medium or high. One-way ANOVA was undertaken to compare maternal education groups for nutrient intakes and the Kruskal-Wallis test used for food consumption. Avon Longitudinal Study of Parents and Children (ALSPAC), Bristol, UK. Children (n 7474) who provided dietary data at age 10 years. A large proportion (60 %) of the sample was classified as plausible reporters, with under-reporting accounting for 36 %. No clear differences were found for intakes of energy or macronutrients between maternal education groups for plausible reporters. However, there were marked differences in micronutrient intakes especially for vitamin C, retinol equivalents and folate, highlighting lower diet quality with lower maternal education level. Intakes of fruit and vegetables showed a positive gradient with increasing maternal education (57 % v. 79 % consumed fresh fruit in low and high educational groups, respectively). A trend towards higher intake in the lower educated group was shown for less healthy foods (meat pies P < 0·001; sausages, burgers and kebabs P < 0·001). The quality of children's diet at 10 years was related to maternal education level. Lower maternal education was associated with less healthy food choices that could be detrimental to health. Further research is needed to establish if these associations can be explained by other socio-economic factors.

Bibliometric Analysis of Orthopedic Literature on Total Knee Arthroplasty in Asian Countries: A 10-year Analysis.

PubMed

Eom, Sang Hwa; Bamne, Ankur B; Chowdhry, Madhav; Chae, Ihn Seok; Kim, Tae Kyun

2015-09-01

We aimed to determine the quantity and quality of research output of selected Asian countries in the field of total knee arthroplasty (TKA) in the last 10 years. Top 15 Asian countries were selected according to their gross domestic product. The Science Citation Index Expanded database was used to search for the literature published between 2004 and 2013 using "Total Knee Arthroplasty". The numbers of articles, journals and citations and the contribution of each country were analyzed. The articles were classified according to the type of study and the relative proportion of each type was analyzed. Asian surgeons have increasingly contributed to orthopedic literature on TKA for the past 10 years, but the dominant contribution came from only a few countries. The total number of articles published by Asian countries increased by 261%, with Japan producing most of the studies and China showing the maximum growth rate. The majority of studies were published in low impact factor journals. Korea published the highest proportion of articles in high impact factor journals. Clinical papers were most frequent. Our identification of research productivity pertaining to TKA among Asian countries gives a unique insight into the level of academic research in the field of TKA in these countries. There is a need to improve the quality of research to enhance the publishing power in high impact journals as well as the need for more basic research and epidemiological studies considering the unique differences among Asian patients undergoing TKA.

[Collagenous gastritis and colitis in a 10-year-old girl].

PubMed

Hangard, P; Lasfargue, M; Rubio, A

2016-07-01

There are few data in the literature on microscopic gastritis and colitis in the pediatric population. The diagnosis is often made after the occurrence of complications. We report the case of a 10.5 year-old girl for whom the diagnosis was made several years after the initial symptoms. Test for infections, inflammation, and auto-immunity yielded normal results. Upper endoscopy and colonoscopy revealed an abnormal mucosa. However, histology showed microscopic inflammation and fibrotic lesions in the lamina propria, and a thick subepithelial collagenous band. This led to the diagnosis of collagenous gastritis and colitis. Budesonide treatment resulted in the cessation of diarrhea and significant weight gain. Treatment by oral budesonide indeed seems to be highly effective but relapses are frequent when the treatment is stopped. This case shows the importance of being vigilant regarding transit disorders with impact on growth kinetics. Upper endoscopy and colonoscopy need to be carried out when children have organic diarrhea with normal blood tests. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Apitherapy Products for Medicinal Use.

PubMed

Fratellone, Patrick M; Tsimis, Flora; Fratellone, Gregory

2016-12-01

For the past 10 years, beekeeping has increased due to a growing awareness of the disappearance of bees since Colony Collapse Disorder. Most of the disappearance of honey bees can be attributed to the use of pesticides. Apitherapy is the science and art of maintaining health with the use of products from the honeybee hive: honey, bee pollen, propolis, royal jelly, and bee venom. We have been beekeeping for the last 10 years. We use every product from the beehive for both personal and patient use.

Community structure and quality after 10 years in two central Ohio mitigation bank wetlands.

PubMed

Spieles, Douglas J; Coneybeer, Meagan; Horn, Jonathan

2006-11-01

We evaluate two 10-year-old mitigation bank wetlands in central Ohio, one created and one with restored and enhanced components, by analysis of vegetation characteristics and by comparison of the year-10 vegetation and macroinvertebrate communities with reference wetlands. To assess different measures of wetland development, we compare the prevalence of native hydrophytes with an index of floristic quality and we evaluate the predictability of these parameters in year 10, given 5 years of data. Results show that the mitigation wetlands in this study meet vegetation performance criteria of native hydrophyte establishment by year 5 and maintain these characteristics through year 10. Species richness and floristic quality, as well as vegetative similarity with reference wetlands, differ among mitigation wetlands in year 1 and also in their rate of change during the first 10 years. The prevalence of native hydrophytes is reasonably predictable by year 10, but 5 years of monitoring is not sufficient to predict future trends of floristic quality in either the created or restored wetland. By year 10, macroinvertebrate taxa richness does not statistically differ among these wetlands, but mitigation wetlands differ from reference sites by tolerance index and by trophic guild dominance. The created wetland herbivore biomass is significantly smaller than its reference, whereas detritivore biomass is significantly greater in the created wetland and smaller in the restored wetland as compared with respective reference wetlands. These analyses illustrate differences in measures of wetland performance and contrast the monitoring duration necessary for legal compliance with the duration required for development of more complex indicators of ecosystem integrity.

Dynamics of erosion in a compressional mountain range revealed by 10Be paleoerosion rates

NASA Astrophysics Data System (ADS)

Val, P.; Hoke, G. D.; Fosdick, J. C.; Wittmann, H.

2015-12-01

The temporal evolution of erosion over million-year timescales is key to understanding the evolution of mountain ranges and adjacent fold-and-thrust belts. While models of orogenic wedge evolution predict an instantaneous response of erosion to pulses of rock uplift, stream-power based landscape evolution models predict catchment-wide erosion maxima that lag behind a rock uplift pulse. Here, we explore the relationships between rock uplift, erosion, and sediment deposition in the Argentine Precordillera fold-and-thrust belt at 30°S where extensive previous work documents deformation, climate and sediment accumulation histories. Sandstone samples spanning 8.8 to 1.8 Ma were collected from the previously dated wedge-top (Iglesia) and foredeep basins (Bermejo) for quartz purification and 10Be extraction. 10Be concentrations due to burial and exhumation were estimated and subtracted from the measured concentrations and yielded the inherited 10Be concentrations, which were then corrected for sample magnetostratigraphic age. The inherited concentrations were then used to calculate paleoerosion rates. We modeled various pre-burial and post-burial exposure scenarios in order to assess potential sources of uncertainty in the recovered paleoerosion rates. The modeling results reveal that pre-burial and post-burial exposure periods only marginally affect our results. By combining the 10Be-derived paleoerosion rates and geomorphic observations with detrital zircon provenance, we document the isolation of the wedge-top basin, which was later reconnected by an upstream migrating pulse of erosion in a process that was directly controlled by thrust activity and base level. The data further indicate that the attainment of maximum upland erosion rates lags maximum rates of deformation and subsidence over million-year timescales. The magnitudes and causes of the erosional delays shed new light on the catchment erosional response to tectonic deformation and rock uplift in orogenic

Solar Spectral Irradiance Reconstruction over 9 Millennia from a Composite 14C and 10Be Series

NASA Astrophysics Data System (ADS)

Wu, C. J.; Usoskin, I. G.; Krivova, N.; Kovaltsov, G.; Solanki, S. K.

2017-12-01

The Sun is the main external energy source to the Earth and thus the knowledge of solar variability on different time scales is important for understanding the solar influence on the terrestrial atmosphere and climate. The overall energy input and its spectral distribution are described by the total (TSI) and spectral (SSI) solar irradiance, respectively. Direct measurements of the solar irradiance provide information on solar variability on the decadal and shorter time scales, while the sunspot number record covers four centuries. On yet longer time scales only indirect proxies can be used, such as the concentrations of the cosmogenic isotopes 10Be and 14C in terrestrial archives. These isotopes are produced in the terrestrial atmosphere by impinging cosmic rays, whose flux is modulated by solar activity. Therefore the isotope data retrieved from various natural archives around the globe show a very high degree of similarity reflecting changes in the solar activity. Nevertheless, significant short-term deviations can be observed due to the different geochemical production processes and local climatic conditions. We will present the newest TSI/SSI reconstruction over the last 9000 years based on a new consistent composite multi-isotope proxy series. The solar irradiance reconstruction reveals the global and robust pattern of solar variability in the past.

Studying 10Be and 11Be Halo States through the (p,d) Single-Neutron Transfer Reaction

NASA Astrophysics Data System (ADS)

Kuhn, Keri; Sarazin, Fred; Tigress Collaboration; ^{(Pcb) 2} Collaboration

2017-09-01

One-neutron transfer reactions are being used to study single-particle neutron states in nuclei. For one-neutron halo nuclei, such as 11Be, the (p,d) reaction enables the removal of the halo neutron or of one of the core neutrons. This way, it is possible to simultaneously study the halo wavefunction of the 11Be ground-state but also a possible excited halo state in 10Be. The 11Be(p, d)10Be transfer reaction at 10 MeV/nucleon is being investigated at the TRIUMF-ISAC II facility with the Printed Circuit Board Based Charged Particle ((PCB)2) array inside the TRIUMF ISAC Gamma-Ray Escape-Suppressed Spectrometer (TIGRESS). The ground state and first excited state of 10Be can be directly identified using deuteron identification and kinematics from the charged particle array, while the four excited states in 10Be around 6 MeV, including the suspected halo state (2- state), are identified using coincident gamma rays from TIGRESS with the identified deuterons. Angular distributions for the 10Be populated states will be shown along with their FRESCO fits. This work is partially supported by the US Department of Energy through Grant/Contract No. DE-FG03- 93ER40789 (Colorado School of Mines).

10 years with Planet Earth essence in the primary school children drawings

NASA Astrophysics Data System (ADS)

D'Addezio, Giuliana

2016-04-01

"10 years with Planet Earth" is the title of the 2016 INGV calendar for primary schools representing the review of a project conceived as support and complement of 15 years long INGV dissemination activities with schools. We realized 10 calendars together with and for primary schools, every year with a subject related to a World in constant evolution. Earthquakes, volcanic eruptions, tsunami waves, magnetic storms and other phenomena are manifestations of the complexity and dynamicity, which began more than four billion years ago and never halted. Since the Earth originated to the first presence of water, life and oxygen, the Cambrian explosion of species, the domain of dinosaurs, the great extinctions and glaciations, the surface of our planet experiences continents collisions, mountains and oceans formation and life forms emerging and disappearing. Every year we have launched a competition asking children to send drawings on themes chosen to stimulate learning about Earth Sciences and Planet Earth dynamics. We intended to raise awareness on issues as water resources availability, protection against natural disasters and control of environmental degradation. For each competition, we chose the most significant drawings to be included in the yearly calendar about the Earth. The authors of drawings were awarded by scientists, journalists, artists and science communicators and even by a minister. Besides the competitions, these drawings depict their own impressions and reflections, providing an opportunity to illustrate the children's point of view. From drawings and texts arise a great consideration and respect for the Planet, raising hopes that similar initiatives can contribute to increase the knowledge of the Earth and of the fragile human ecosystem in the hearts and minds of future active citizens. The project was made possible thanks to the teachers and to the wonderful students of more than 200 schools that sent about 10,000 drawings that have intrigued

Penile injuries: A 10-year experience

PubMed Central

Krishna Reddy, S.V.; Shaik, Ahammad Basha; Sreenivas, K.

2014-01-01

We report our 10-year experience with penile injuries. We retrospectively reviewed the records of 156 cases of male external genitalia injuries between May 2002 and December 2012. Of these, only 26 patients presented without urethral injuries and were included in this study. Patients were divided into 4 groups: Group 1 (n = 12) with patients with penile fractures injuries; Group 2 (n = 5) with patients with penile amputation injuries; Group 3 (n = 2) with patients with penile penetrating injuries; and Group 4 (n = 7) with patients with penile soft tissue injuries. Grading of injury was done using the American Association for the Surgery of Trauma (AAST)-Organ injury scale of penile injury. Penile injuries without urethral injuries are urological emergencies which require immediate attention. PMID:25295134

Illness Perception Profiles and Their Association with 10-Year Survival Following Cardiac Valve Replacement.

PubMed

Crawshaw, Jacob; Rimington, Helen; Weinman, John; Chilcot, Joseph

2015-10-01

The aim of the present study was to examine whether profiles of illness perceptions are associated with 10-year survival following cardiac valve replacement surgery. Illness perceptions were evaluated in 204 cardiac patients awaiting first-time valve replacement and again 1 year post-operatively using cluster analysis. All-cause mortality was recorded over a 10-year period. At 1 year, 136 patients were grouped into one of four profiles (stable positive, stable negative, changed from positive to negative, changed from negative to positive). The median follow-up was 3063 days (78 deaths). After controlling for clinical covariates, including markers of function, patients who changed illness perceptions from positive to negative beliefs 1 year post-surgery had an increased mortality risk (hazard ratio (HR) = 3.2, 95% confidence interval (CI) 1.2-8.3, p = .02) compared to patients who held positive stable perceptions. Following cardiac valve replacement, developing negative illness perceptions over the first post-operative year predicts long-term mortality. Early screening and intervention to alter this pattern of beliefs may be beneficial.

Do gender disparities persist in gastroenterology after 10 years of practice?

PubMed

Singh, Aparajita; Burke, Carol A; Larive, Brett; Sastri, Suriya V

2008-07-01

Cross-sectional studies confirm gender disparity in many aspects of the practice of medicine and surgery. Some data suggest the disparities diminish after 10 yr of practice. This study aims to examine gender discrepancies in income, social, and professional status of gastroenterologists after 10 yr of practice. Prospective, observational, cohort study of gastroenterologists incepted upon graduation from a U.S. GI fellowship program in 1993 and 1995. A 36-item questionnaire was sent to the cohort at 3, 5, and 10 yr after graduation from GI fellowship training. The following are the results of the final, 10th year survey. A total of 168 men and 25 women (mean age 45.5 yr) responded. Men and women were equally likely to be board certified and married, however, women had fewer children. Men earned a mean annual gross income of $375,000 versus$245,000 for women (P= 0.001). After adjusting for practice setting, work hours, practice-ownership, free endoscopy center practice, and vacation time, female gastroenterologists earned $82,000 (22%) less per year than their male colleagues (95% CI $34,000-130,000, P= 0.001). Women were more frequently in academic practice (38%vs 17%), but were less likely to hold the most advanced academic positions. After 10 yr of practice, significant economic, professional, and social disparities persist between male and female gastroenterologists in this cohort. Women were more likely to practice in a setting with flexible work hours, a family leave provision, and in a practice with other women. Initiatives to equalize pay and ensure opportunities for professional advancement for women may diminish the significant practice disparities incurred by women in gastroenterology.

Constraints on Water Reservoir Lifetimes From Catchment-Wide 10Be Erosion Rates—A Case Study From Western Turkey

NASA Astrophysics Data System (ADS)

Heineke, Caroline; Hetzel, Ralf; Akal, Cüneyt; Christl, Marcus

2017-11-01

The functionality and retention capacity of water reservoirs is generally impaired by upstream erosion and reservoir sedimentation, making a reliable assessment of erosion indispensable to estimate reservoir lifetimes. Widely used river gauging methods may underestimate sediment yield, because they do not record rare, high-magnitude events and may underestimate bed load transport. Hence, reservoir lifetimes calculated from short-term erosion rates should be regarded as maximum values. We propose that erosion rates from cosmogenic 10Be, which commonly integrate over hundreds to thousands of years, are useful to complement short-term sediment yield estimates and should be employed to estimate minimum reservoir lifetimes. Here we present 10Be erosion rates for the drainage basins of six water reservoirs in Western Turkey, which are located in a tectonically active region with easily erodible bedrock. Our 10Be erosion rates for these catchments are high, ranging from ˜170 to ˜1,040 t/km2/yr. When linked to reservoir volumes, they yield minimum reservoir lifetimes between 25 ± 5 and 1,650 ± 360 years until complete filling, with four reservoirs having minimum lifespans of ≤110 years. In a neighboring region with more resistant bedrock and less tectonic activity, we obtain much lower catchment-wide 10Be erosion rates of ˜33 to ˜95 t/km2/yr, illustrating that differences in lithology and tectonic boundary conditions can cause substantial variations in erosion even at a spatial scale of only ˜50 km. In conclusion, we suggest that both short-term sediment yield estimates and 10Be erosion rates should be employed to predict the lifetimes of reservoirs.

Residual lifetime and 10 year absolute risks of osteoporotic fractures in Chinese men and women.

PubMed

Si, Lei; Winzenberg, Tania M; Chen, Mingsheng; Jiang, Qicheng; Palmer, Andrew J

2015-06-01

To determine the residual lifetime and 10 year absolute risks of osteoporotic fractures in Chinese men and women. A validated state-transition microsimulation model was used. Microsimulation and probabilistic sensitivity analyses were performed to address the uncertainties in the model. All parameters including fracture incidence rates and mortality rates were retrieved from published literature. Simulated subjects were run through the model until they died to estimate the residual lifetime fracture risks. A 10 year time horizon was used to determine the 10 year fracture risks. We estimated the risk of only the first osteoporotic fracture during the simulation time horizon. The residual lifetime and 10 year risks of having the first osteoporotic (hip, clinical vertebral or wrist) fracture for Chinese women aged 50 years were 40.9% (95% CI: 38.3-44.0%) and 8.2% (95% CI: 6.8-9.3%) respectively. For men, the residual lifetime and 10 year fracture risks were 8.7% (95% CI: 7.5-9.8%) and 1.2% (95% CI: 0.8-1.7%) respectively. The residual lifetime fracture risks declined with age, whilst the 10 year fracture risks increased with age until the short-term mortality risks outstripped the fracture risks. Residual lifetime and 10 year clinical vertebral fracture risks were higher than those of hip and wrist fractures in both sexes. More than one third of the Chinese women and approximately one tenth of the Chinese men aged 50 years are expected to sustain a major osteoporotic fracture in their remaining lifetimes. Due to increased fracture risks and a rapidly ageing population, osteoporosis will present a great challenge to the Chinese healthcare system. While national data was used wherever possible, regional Chinese hip and clinical vertebral fracture incidence rates were used, wrist fracture rates were taken from a Norwegian study and calibrated to the Chinese population. Other fracture sites like tibia, humerus, ribs and pelvis were not included in the analysis, thus these

Tuskegee Bioethics Center 10th anniversary presentation: "Commemorating 10 years: ethical perspectives on origin and destiny".

PubMed

Prograis, Lawrence J

2010-08-01

More than 70 years have passed since the beginning of the Public Health Service syphilis study in Tuskegee, Alabama, and it has been over a decade since President Bill Clinton formally apologized for it and held a ceremony for the Tuskegee study participants. The official launching of the Tuskegee University National Center for Bioethics in Research and Health Care took place two years after President Clinton's apology. How might we fittingly discuss the Center's 10th Anniversary and the topic 'Commemorating 10 Years: Ethical Perspectives on Origin and Destiny'? Over a decade ago, a series of writers, many of them African Americans, wrote a text entitled 'African-American Perspectives on Biomedical Ethics'; their text was partly responsible for a prolonged reflection by others to produce a subsequent work, 'African American Bioethics: Culture, Race and Identity'. What is the relationship between the discipline of bioethics and African American culture? This and related questions are explored in this commentary.

Validation of 10 years of SAO OMI Ozone Profiles with Ozonesonde and MLS Observations

NASA Astrophysics Data System (ADS)

Huang, G.; Liu, X.; Chance, K.; Bhartia, P. K.

2015-12-01

To evaluate the accuracy and long-term stability of the SAO OMI ozone profile product, we validate ~10 years of ozone profile product (Oct. 2004-Dec. 2014) against collocated ozonesonde and MLS data. Ozone profiles as well stratospheric, tropospheric, lower tropospheric ozone columns are compared with ozonesonde data for different latitude bands, and time periods (e.g., 2004-2008/2009-2014 for without/with row anomaly. The mean biases and their standard deviations are also assessed as a function of time to evaluate the long-term stability and bias trends. In the mid-latitude and tropical regions, OMI generally shows good agreement with ozonesonde observations. The mean ozone profile biases are generally within 6% with up to 30% standard deviations. The biases of stratospheric ozone columns (SOC) and tropospheric ozone columns (TOC) are -0.3%-2.2% and -0.2%-3%, while standard deviations are 3.9%-5.8% and 14.4%-16.0%, respectively. However, the retrievals during 2009-2014 show larger standard deviations and larger temporal variations; the standard deviations increase by ~5% in the troposphere and ~2% in the stratosphere. Retrieval biases at individual levels in the stratosphere and upper troposphere show statistically significant trends and different trends for 2004-2008 and 2009-2014 periods. The trends in integrated ozone partial columns are less significant due to cancellation from various layers, except for significant trend in tropical SOC. These results suggest the need to perform time dependent radiometric calibration to maintain the long-term stability of this product. Similarly, we are comparing the OMI stratospheric ozone profiles and SOC with collocated MLS data, and the results will be reported.

CO2 and N-fertilization effects on fine-root length, production, and mortality: a 4-year ponderosa pine study.

PubMed

Phillips, Donald L; Johnson, Mark G; Tingey, David T; Storm, Marjorie J; Ball, J Timothy; Johnson, Dale W

2006-06-01

We conducted a 4-year study of juvenile Pinus ponderosa fine root (< or =2 mm) responses to atmospheric CO2 and N-fertilization. Seedlings were grown in open-top chambers at three CO2 levels (ambient, ambient+175 mumol/mol, ambient+350 mumol/mol) and three N-fertilization levels (0, 10, 20 g m(-2) year(-1)). Length and width of individual roots were measured from minirhizotron video images bimonthly over 4 years starting when the seedlings were 1.5 years old. Neither CO2 nor N-fertilization treatments affected the seasonal patterns of root production or mortality. Yearly values of fine-root length standing crop (m m(-2)), production (m m(-2) year(-1)), and mortality (m m(-2) year(-1)) were consistently higher in elevated CO2 treatments throughout the study, except for mortality in the first year; however, the only statistically significant CO2 effects were in the fine-root length standing crop (m m(-2)) in the second and third years, and production and mortality (m m(-2) year(-1)) in the third year. Higher mortality (m m(-2) year(-1)) in elevated CO2 was due to greater standing crop rather than shorter life span, as fine roots lived longer in elevated CO2. No significant N effects were noted for annual cumulative production, cumulative mortality, or mean standing crop. N availability did not significantly affect responses of fine-root standing crop, production, or mortality to elevated CO2. Multi-year studies at all life stages of trees are important to characterize belowground responses to factors such as atmospheric CO2 and N-fertilization. This study showed the potential for juvenile ponderosa pine to increase fine-root C pools and C fluxes through root mortality in response to elevated CO2.

Modeling of process parameters for enhanced production of coenzyme Q10 from Rhodotorula glutinis.

PubMed

Balakumaran, Palanisamy Athiyaman; Meenakshisundaram, Sankaranarayanan

2015-01-01

Coenzyme Q10 (CoQ10) plays an indispensable role in ATP generation through oxidative phosphorylation and helps in scavenging superoxides generated during electron transfer reactions. It finds extensive applications specifically related to oxidative damage and metabolic dysfunctions. This article reports the use of a statistical approach to optimize the concentration of key variables for the enhanced production of CoQ10 by Rhodotorula glutinis in a lab-scale fermenter. The culture conditions that promote optimum growth and CoQ10 production were optimized and the interaction of significant variables para-hydroxybenzoic acid (PHB, 819.34 mg/L) and soybean oil (7.78% [v/v]) was studied using response surface methodology (RSM). CoQ10 production increased considerably from 10 mg/L (in control) to 39.2 mg/L in batch mode with RSM-optimized precursor concentration. In the fed-batch mode, PHB and soybean oil feeding strategy enhanced CoQ10 production to 78.2 mg/L.

Deterioration of mental health in bariatric surgery after 10 years despite successful weight loss.

PubMed

Canetti, L; Bachar, E; Bonne, O

2016-01-01

The present study evaluated the mental health and psychological functioning of bariatric patients before surgery, and after 1 year and 10 year follow-ups, and compared them with participants in a dietary program. Such long follow-up is rare, but strongly recommended by the American Association of Bariatric Surgeons. Thirty-six bariatric surgery patients and 34 participants of a weight loss program were weighed and assessed at all 3 points in time. Participants were administered the mental health inventory, neuroticism, sense of control and fear of intimacy scales. Along with these mental and psychological measurements, the medical outcome short form (SF-36) was used. The surgery group achieved successful weight loss outcomes (27% reduction of pre-operative weight) after 10 years and better than baseline health-related quality-of-life scores. However, their general mental health, neuroticism, sense of control and fear of intimacy scores showed significant deterioration in comparison to pre-operative levels after 10 years. The dietary group participants remained psychologically stable among all three points in time. This study highlights the importance of identifying a risk group among bariatric patients for which the dietary and psychological follow-up may be of special significance.

10 years of surveillance of human tularaemia in France.

PubMed

Mailles, A; Vaillant, V

2014-11-13

Tularaemia has been mandatorily notifiable in France since October 2002. The surveillance aims to detect early any infection possibly due to bioterrorism and to follow up disease trends. We report the results of national surveillance from 2002 to 2012. A case is defined as a patient with clinical presentation suggestive of tularaemia and biological confirmation of infection or an epidemiological link with a biologically confirmed case. Clinical, biological and epidemiological data are collected using a standardised notification form. From 2002 to 2012, 433 cases were notified, with a median age of 49 years (range 2 to 95 years) and a male–female sex ratio of 1.8. Most frequent clinical presentations were glandular tularaemia (n=200; 46%) and ulceroglandular tularaemia (n=113; 26%). Most frequent at-risk exposures were handling hares (n=179; 41%) and outdoor leisure exposure to dust aerosols (n=217; 50%). Tick bites were reported by 82 patients (19%). Ten clusters (39 cases) were detected over the 10-year period, as well as a national outbreak during winter 2007/2008. The tularaemia surveillance system is able to detect small clusters as well as major outbreaks. Surveillance data show exposure to dust aerosols during outdoor leisure activities to be a major source of contamination in France.

The relationship between household income and dietary intakes of 1-10 year old urban Malaysian.

PubMed

Mohd Shariff, Zalilah; Lin, Khor Geok; Sariman, Sarina; Lee, Huang Soo; Siew, Chin Yit; Mohd Yusof, Barakatun Nisak; Mun, Chan Yoke; Mohamad, Maznorila

2015-06-01

Diet plays an important role in growth and development of children. However, dietary intakes of children living in either rural or urban areas can be influenced by household income. This cross-sectional study examined energy, nutrient and food group intakes of 749 urban children (1-10 years old) by household income status. Children's dietary intakes were obtained using food recall and record for two days. Diet adequacy was assessed based on recommended intakes of energy and nutrients and food group servings. For toddlers, all nutrients except dietary fiber (5.5 g) exceeded recommended intakes. Among older children (preschoolers and school children), calcium (548 mg, 435 mg) and dietary fiber (7.4 g, 9.4 g) did not meet recommendations while percentage of energy from total fat and saturated fats exceeded 30% and 10%, respectively. The mean sodium intakes of preschoolers (1,684 mg) and school children (2,000 mg) were relatively high. Toddlers in all income groups had similar energy and nutrient intakes and percentages meeting the recommended intakes. However, low income older children had lowest intakes of energy (P < 0.05) and most nutrients (P < 0.05) and highest proportions that did not meet recommended energy and nutrient intakes. For all food groups, except milk and dairy products, all age groups had mean intakes below the recommended servings. Compared to middle and high income groups, low income preschoolers had the lowest mean intake of fruits (0.07 serving), meat/poultry (0.78 serving) and milk/dairy products (1.14 serving) while low income toddlers and school children had the least mean intake of fruits (0.09 serving) and milk/dairy products (0.54 serving), respectively. Low socioeconomic status, as indicated by low household income, could limit access to adequate diets, particularly for older children. Parents and caregivers may need dietary guidance to ensure adequate quantity and quality of home food supply and foster healthy eating habits in children.

Alpine Cliff Backwearing Rates Derived From Cosmogenic 10-Be in Active Medial Moraines

NASA Astrophysics Data System (ADS)

Ward, D. J.; Anderson, R. S.

2008-12-01

-order interpretation of these results yields minimum erosion rates of 0.2 to 0.5 mm/yr, consistent with erosion rates measured by various means in other glacial environments. This interpretation assumes a simple source area geometry and 10Be production rate scaling. To interpret these measurements in their full geological and topographic context, we present numerical models to describe how the expected distribution of 10Be concentrations should vary with erosion rate. This relationship is affected by source area hypsography and the distributions of size and recurrence interval of rockfall events. We randomly sample events based on a power-law size-recurrence relationship (constrained by field observations) from a numerical grid of production rates derived from a DEM of the source area. This yields the expected probability distribution of 10Be concentrations in the rockfall debris for a given mean erosion rate, weighted by event volume and source hypsography. The measured 10Be concentrations are low enough that accumulation during burial, exhumation, and transport in the medial moraine could account for up to ~1/4 of the signal, given our best estimates of glacier's surface speed (~30 m/yr). The slight downvalley increase in the concentrations supports a component of exposure in the moraine during transport. The amount of exposure depends on factors such as the entry and exit points of debris incorporated into the glacial ice, and the glacial mass balance pattern, and downvalley surface speed. We assess these effects with analytical and numerical models of debris transport in medial moraines, following Anderson (2000).

Insights into Meteoric 10Be Dynamics and Climate Stability along the Hawaiian Kohala Climosequence

NASA Astrophysics Data System (ADS)

Dixon, J. L.; Chadwick, O.

2017-12-01

We measure meteoric 10Be in soils across a well-studied climate gradient spanning Kohala, Hawaii to provide new understanding of the isotope behavior in soils and constraints on nuclide delivery rates to Earth's surface. Annual rainfall across the Kohala climogradient varies from 16 - 300 cm, with Hawaiian soils reflecting evolution over the past 150 ka, the nominal age of the volcanic parent material. We analyzed a sequence of nine soil profiles for meteoric 10Be and compared with previously measured data on soil chemistry and dust fluxes. In the Kohala system, soil inventories of 10Be span 40-300 x 109 atom/cm2 and generally increase linearly with rainfall, consistent with precipitation-driven fluxes and the high retention of 10Be in clay-rich soil horizons. However, nuclide inventories dramatically decrease for soils at rainfall >140 cm/y. The observed decrease corresponds with other strong changes in weathering intensity across the climate gradient, associated with previously studied and recognized pedogenic thresholds. These thresholds represent abrupt transitions in soil chemistry related to increased throughflow of soil solutions, decreases in base saturation and pH, and the destruction of phyllosilicates and replacement with amorphous oxyhydroxides. Meteoric-derived ages, based on 10Be-flux estimates and measured inventories are uniform for dry soils ( 60ka), but far less than the known substrate age (150ka), indicating that actual delivery rates are lower than predicted from current models in this region. Despite the offset in predicted and substrate ages, the consistency in pattern suggests that the rainfall gradient over the 150 thousand years of soil development has not deviated significantly from its present structure. Furthermore, based on clear 10Be losses in soils with high moisture availability, our results indicate meteoric 10Be may not be a robust tracer of soil age and movement in systems with high rainfall and weathering intensity and low soil

40 CFR 35.910-10 - Allotment of Fiscal Year 1979 appropriation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Allotment of Fiscal Year 1979 appropriation. 35.910-10 Section 35.910-10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.910-10 Allotment of Fiscal Yea...

40 CFR 35.910-10 - Allotment of Fiscal Year 1979 appropriation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Allotment of Fiscal Year 1979 appropriation. 35.910-10 Section 35.910-10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.910-10 Allotment of Fiscal Yea...

40 CFR 35.910-10 - Allotment of Fiscal Year 1979 appropriation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Allotment of Fiscal Year 1979 appropriation. 35.910-10 Section 35.910-10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.910-10 Allotment of Fiscal Yea...

40 CFR 35.910-10 - Allotment of Fiscal Year 1979 appropriation.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Allotment of Fiscal Year 1979 appropriation. 35.910-10 Section 35.910-10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.910-10 Allotment of Fiscal Yea...

40 CFR 35.910-10 - Allotment of Fiscal Year 1979 appropriation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Allotment of Fiscal Year 1979 appropriation. 35.910-10 Section 35.910-10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.910-10 Allotment of Fiscal Yea...

Just the right age: well-clustered exposure ages from a global glacial 10Be compilation

NASA Astrophysics Data System (ADS)

Heyman, Jakob; Margold, Martin

2017-04-01

Cosmogenic exposure dating has been used extensively for defining glacial chronologies, both in ice sheet and alpine settings, and the global set of published ages today reaches well beyond 10,000 samples. Over the last few years, a number of important developments have improved the measurements (with well-defined AMS standards) and exposure age calculations (with updated data and methods for calculating production rates), in the best case enabling high precision dating of past glacial events. A remaining problem, however, is the fact that a large portion of all dated samples have been affected by prior and/or incomplete exposure, yielding erroneous exposure ages under the standard assumptions. One way to address this issue is to only use exposure ages that can be confidently considered as unaffected by prior/incomplete exposure, such as groups of samples with statistically identical ages. Here we use objective statistical criteria to identify groups of well-clustered exposure ages from the global glacial "expage" 10Be compilation. Out of ˜1700 groups with at least 3 individual samples ˜30% are well-clustered, increasing to ˜45% if allowing outlier rejection of a maximum of 1/3 of the samples (still requiring a minimum of 3 well-clustered ages). The dataset of well-clustered ages is heavily dominated by ages <30 ka, showing that well-defined cosmogenic chronologies primarily exist for the last glaciation. We observe a large-scale global synchronicity in the timing of the last deglaciation from ˜20 to 10 ka. There is also a general correlation between the timing of deglaciation and latitude (or size of the individual ice mass), with earlier deglaciation in lower latitudes and later deglaciation towards the poles. Grouping the data into regions and comparing with available paleoclimate data we can start to untangle regional differences in the last deglaciation and the climate events controlling the ice mass loss. The extensive dataset and the statistical analysis

Mistakes in diagnosing non-accidental injury: 10 years' experience

PubMed Central

Wheeler, David M; Hobbs, Christopher J

1988-01-01

Fifty children who were referred to the child abuse team in Leeds over the 10 years 1976-86 with suspected non-accidental injury were found to have conditions which mimicked non-accidental injury. These included impetigo (nine children) and blue spots (five children). Five children who presented with multiple bruising had haemostatic disorders. Eight children had disorders of the bone. Five children had been previously abused physically. Four showed evidence of neglect. One had evidence of non-accidental injury as well as the condition mimicking abuse. It is emphasised that when child abuse is suspected a sensitive and thorough assessment should be carried out by a paediatrician who is experienced in this. ImagesFIG 1 PMID:3133026

Years of potential life lost and productivity costs because of cancer mortality and for specific cancer sites where human papillomavirus may be a risk factor for carcinogenesis-United States, 2003.

PubMed

Ekwueme, Donatus U; Chesson, Harrell W; Zhang, Kevin B; Balamurugan, Appathurai

2008-11-15

Although years of potential life lost (YPLL) and mortality-related productivity costs comprise a substantial portion of the burden of cancers where human papillomavirus (HPV) may be a risk factor for carcinogenesis (called HPV-associated cancers in this report), estimates of these costs are limited. The authors estimated the mortality-related burden (in terms of YPLL and productivity costs) of HPV-associated cancers (without regard to the percentage of each of these cancers that could be attributed to HPV) and all malignant cancers in the United States in 2003. The authors used 2003 national mortality data and US life tables to estimate YPLL for HPV-associated cancers and all malignant cancers. YPLL was estimated by using the life expectancy method. The human capital approach was used to estimate the value of the expected future lifetime productivity losses caused by premature deaths from HPV-associated cancers and all malignant cancers. Indirect mortality costs were estimated as the product of the number of deaths and the expected value of individuals' future earnings, including an imputed value of housekeeping services. In 2003, HPV-associated cancers accounted for 181,026 YPLL, which represented 2.4% of the estimated 7.5 million YPLL attributable to all malignant cancers in the United States. The average number of YPLL was 21.8 per HPV-associated cancer death and 16.3 per death from overall malignant cancers. Overall, HPV-associated cancers had the largest relative contribution to YPLL in women ages 30 to 34 years. The lifetime productivity cost from mortality in 2003 was $3.7 billion for HPV-associated cancer mortality and $133.5 billion for overall malignant cancer mortality. HPV-associated cancers impose a considerable burden in terms of premature deaths and productivity losses.

Global outcome, productivity and epilepsy 3--8 years after severe head injury. The impact of injury severity.

PubMed

Skandsen, Toril; Ivar Lund, Tom; Fredriksli, Oddrun; Vik, Anne

2008-07-01

To assess long-term outcome in survivors after severe head injury and relate outcome to injury severity. Follow-up 3-8 years post injury in a retrospectively collected sample. A neurosurgical department in a regional trauma centre. Of 146 individuals admitted, 135 were actively treated. Twenty-four per cent of these died within six months. Ninety-three of the 94 (aged 1-88 years) who survived more than three years were included in the follow-up. They were separated into groups based on their level of consciousness at four weeks post injury: oriented (n = 39), confused (n = 22) or in a minimally conscious/vegetative state (MCS/VS) (n = 26) and not possible to assess (n = 6). Glasgow Outcome Scale Extended (GOSE), participation in work/education (productivity) and posttraumatic epilepsy. GOSE scores were: vegetative state: 3%, severe disability: 28% (22% lower level, 6% upper level), moderate disability: 39% (22% lower level, 17% upper level) and good recovery: 27% (10% lower level, 17% upper level). Productivity was 34% (aged 7-64 years). The three severity groups had different GOSE scores (P<0.001) and different proportion of productive individuals (P<0.001). Twenty-three per cent experienced posttraumatic epilepsy and this was significantly associated with the highest injury severity (P<0.001) and intracranial surgery (P = 0.01). Being independent in daily life but unable to work was the typical long-term outcome. Stratifying the patients based on consciousness at four weeks we found different outcomes. Among oriented patients, almost all regained independency, whereas in the most severe group, poor outcomes and posttraumatic epilepsy was common.

Case Report: Bullous Scabies in Two Children below 10 Years.

PubMed

Luo, Ze-Yu; Zeng, Mei; Gao, Qian; Zhao, Yu-Kun; Sarkar, Rashmi; Liao, Shu-Ping; Luo, Di-Qing

2017-12-01

Bullous scabies is an infrequent and atypical presentation of scabies, with predilection for elderly and males. Its median age of presentation is 70 years. We report two male cases of bullous scabies who were 7 years and 6 months old. Both patients had excellent response to sulfur 10% ointment alone and have had no recurrence in more than 3 months of follow-up.

Twenty-million-year relationship between mammalian diversity and primary productivity

NASA Astrophysics Data System (ADS)

Fritz, Susanne A.; Eronen, Jussi T.; Schnitzler, Jan; Hof, Christian; Janis, Christine M.; Mulch, Andreas; Böhning-Gaese, Katrin; Graham, Catherine H.

2016-09-01

At global and regional scales, primary productivity strongly correlates with richness patterns of extant animals across space, suggesting that resource availability and climatic conditions drive patterns of diversity. However, the existence and consistency of such diversity-productivity relationships through geological history is unclear. Here we provide a comprehensive quantitative test of the diversity-productivity relationship for terrestrial large mammals through time across broad temporal and spatial scales. We combine >14,000 occurrences for 690 fossil genera through the Neogene (23-1.8 Mya) with regional estimates of primary productivity from fossil plant communities in North America and Europe. We show a significant positive diversity-productivity relationship through the 20-million-year record, providing evidence on unprecedented spatial and temporal scales that this relationship is a general pattern in the ecology and paleo-ecology of our planet. Further, we discover that genus richness today does not match the fossil relationship, suggesting that a combination of human impacts and Pleistocene climate variability has modified the 20-million-year ecological relationship by strongly reducing primary productivity and driving many mammalian species into decline or to extinction.

Cost savings associated with 10 years of road safety policies in Catalonia, Spain

PubMed Central

Suelves, Josep M; Barbería, Eneko

2013-01-01

Abstract Objective To determine whether the road safety policies introduced between 2000 and 2010 in Catalonia, Spain, which aimed primarily to reduce deaths from road traffic collisions by 50% by 2010, were associated with economic benefits to society. Methods A cost analysis was performed from a societal perspective with a 10-year time horizon. It considered the costs of: hospital admissions; ambulance transport; autopsies; specialized health care; police, firefighter and roadside assistance; adapting to disability; and productivity lost due to institutionalization, death or sick leave of the injured or their caregivers; as well as material and administrative costs. Data were obtained from a Catalan hospital registry, the Catalan Traffic Service information system, insurance companies and other sources. All costs were calculated in euros (€) at 2011 values. Findings A substantial reduction in deaths from road traffic collisions was observed between 2000 and 2010. Between 2001 and 2010, with the implementation of new road safety policies, there were 26 063 fewer road traffic collisions with victims than expected, 2909 fewer deaths (57%) and 25 444 fewer hospitalizations. The estimated total cost savings were around €18 000 million. Of these, around 97% resulted from reductions in lost productivity. Of the remaining cost savings, 63% were associated with specialized health care, 15% with adapting to disability and 8.1% with hospital care. Conclusion The road safety policies implemented in Catalonia in recent years were associated with a reduction in the number of deaths and injuries from traffic collisions and with substantial economic benefits to society. PMID:23397348

Meteoric 10Be as a tool to investigate human induced soil fluxes: a conceptual model

NASA Astrophysics Data System (ADS)

Campforts, Benjamin; Govers, Gerard; Vanacker, Veerle; De Vente, Joris; Boix-Fayos, Carolina; Minella, Jean; Baken, Stijn; Smolders, Erik

2014-05-01

The use of meteoric 10Be as a tool to understand long term landscape behavior is becoming increasingly popular. Due its high residence time, meteoric 10Be allows in principle to investigate in situ erosion rates over time scales exceeding the period studied with classical approaches such as 137Cs. The use of meteoric 10Be strongly contributes to the traditional interpretation of sedimentary archives which cannot be unequivocally coupled to sediment production and could provide biased information over longer time scales (Sadler, 1981). So far, meteoric 10Be has successfully been used in geochemical fingerprinting of sediments, to date soil profiles, to assess soil residence times and to quantify downslope soil fluxes using accumulated 10Be inventories along a hill slope. However, less attention is given to the potential use of the tracer to directly asses human induced changes in soil fluxes through deforestation, cultivation and reforestation. A good understanding of the processes governing the distribution of meteoric 10Be both within the soil profile and at landscape scale is essential before meteoric 10Be can be successfully applied to assess human impact. We developed a spatially explicit 2D-model (Be2D) in order to gain insight in meteoric 10Be movement along a hillslope that is subject to human disturbance. Be2D integrates both horizontal soil fluxes and vertical meteoric 10Be movement throughout the soil prolife. Horizontal soil fluxes are predicted using (i) well studied geomorphical laws for natural erosion and soil formation as well as (ii) human accelerated water and tillage erosion. Vertical movement of meteoric 10Be throughout the soil profile is implemented by inserting depth dependent retardation calculated using experimentally determined partition coefficients (Kd). The model was applied to different environments such as (i) the Belgian loess belt, characterized by aeolian deposits enriched in inherited meteoric 10Be, (ii) highly degraded and stony

Foreign body aspiration and language spoken at home: 10-year review.

PubMed

Choroomi, S; Curotta, J

2011-07-01

To review foreign body aspiration cases encountered over a 10-year period in a tertiary paediatric hospital, and to assess correlation between foreign body type and language spoken at home. Retrospective chart review of all children undergoing direct laryngobronchoscopy for foreign body aspiration over a 10-year period. Age, sex, foreign body type, complications, hospital stay and home language were analysed. At direct laryngobronchoscopy, 132 children had foreign body aspiration (male:female ratio 1.31:1; mean age 32 months (2.67 years)). Mean hospital stay was 2.0 days. Foreign bodies most commonly comprised food matter (53/132; 40.1 per cent), followed by non-food matter (44/132; 33.33 per cent), a negative endoscopy (11/132; 8.33 per cent) and unknown composition (24/132; 18.2 per cent). Most parents spoke English (92/132, 69.7 per cent; vs non-English-speaking 40/132, 30.3 per cent), but non-English-speaking patients had disproportionately more food foreign bodies, and significantly more nut aspirations (p = 0.0065). Results constitute level 2b evidence. Patients from non-English speaking backgrounds had a significantly higher incidence of food (particularly nut) aspiration. Awareness-raising and public education is needed in relevant communities to prevent certain foods, particularly nuts, being given to children too young to chew and swallow them adequately.

The reductions in monetary cost and gains in productivity with methadone maintenance treatment: one year follow-up.

PubMed

Hsiao, Chih Yin; Chen, Kao Chin; Lee, Lan-Ting; Tsai, Hsin Chun; Chang, Wei Hung; Lee, I Hui; Chen, Po See; Lu, Ru-Band; Yang, Yen Kuang

2015-02-28

While methadone maintenance treatment (MMT) is beneficial for heroin dependence, there is little information regarding the reductions in monetary cost and gains in productivity following MMT. The aim of this study was to evaluate the changes in the monetary cost of heroin addiction and productivity after one year of MMT. Twenty-nine participants from an MMT clinic were included. The monetary cost, productivity, quality of life (QOL) and mental health status were assessed at both baseline and one year follow-up. The average annual total cost was approximately US$26,485 (1.43 GDP per capita in 2010) at baseline, and decreased by 59.3% to US$10,784 (0.58 GDP) at follow-up. The mean number of months of unemployment dropped from 6.03 to 2.79, the mean income increased to exceed the basic salary, but only reached 45.3% of the national average monthly earnings. The participants׳ mental health improved, but their QOL scores did not increase significantly. After one year of MMT, the monetary cost of heroin addiction fell, both the productivity and mental health of the participants׳ improved, but limited gains were seen with regard to their QOL. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Maxillofacial Injuries in Children: A 10 year Retrospective Study.

PubMed

Kambalimath, H V; Agarwal, S M; Kambalimath, Deepashri H; Singh, Mamta; Jain, Neha; Michael, P

2013-06-01

Fractures of facial bones in children are relatively uncommon although both children and adults are subjected to similar types of injuries. This study aims to evaluate the epidemiology of facial bone fractures among children under 14 years, their management and outcome. This retrospective study included maxillofacial injuries treated in 112 children under 14 years admitted due to maxillofacial injuries during the period from 2001 to 2011. Of them ten (8.93 %) were below 5 years, 44 (39.29 %) between 6 and 10 years and 58 (51.78 %) between 11 and 14 years of age. Male to female ratio was 1.8:1. Fall from a height was the most common etiology. The most common jaw involved in the fracture was the mandible. Conservative management was done in 83.04 % of cases and open reduction and internal fixation was performed in 16.96 % of cases. Five (4.46 %) cases accounted for post-operative wound infection. Fracture of the mandible is the most common maxillofacial injury in children, most often caused by fall from a height. The osteogenic potential of the mandible in children leads to conservative management of these fractures. Opportunities for prevention of maxillofacial trauma should be taken into consideration by parents and care takers.

Long-term outcomes after Roux-en-Y gastric bypass: 10- to 13-year data.

PubMed

Obeid, Nabeel R; Malick, Waqas; Concors, Seth J; Fielding, George A; Kurian, Marina S; Ren-Fielding, Christine J

2016-01-01

Short- and mid-term data on Roux-en-Y gastric bypass (RYGB) indicate sustained weight loss and improvement in co-morbidities. Few long-term studies exist, some of which are outdated, based on open procedures or different techniques. To investigate long-term weight loss, co-morbidity remission, nutritional status, and complication rates among patients undergoing RYGB. An academic, university hospital in the United States. Between October 2000 and January 2004, patients who underwent RYGB≥10 years before study onset were eligible for chart review, office visits, and telephone interviews. Revisional surgery was an endpoint, ceasing eligibility for study follow-up. Outcomes included weight loss measures and rates of co-morbidity remission, complications, and nutritional deficiencies. RYGB was performed in 328 patients with a mean preoperative body mass index of 47.5 kg/m(2). Of 294 eligible patients, 134 (46%) were contacted for follow-up at ≥ 10 years (10+Year follow-up). Mean percentage excess weight loss (%EWL) was 58.9% at 10+Year. Higher %EWL was achieved by non-super-obese versus super-obese (61.3% versus 52.9%, P = .034). Blood pressure, lipid panel, and hemoglobin A1c improved significantly. At 10 years, remission of co-morbidities was 46% for hypertension and hyperlipidemia and 58% for diabetes mellitus. Thirty patients (9%) had revisional surgery for weight regain. Sixty-four patients (19.5%) had long-term complications requiring surgery. All-cause mortality was 2.7%. Nutritional deficiencies were seen in 87% of patients. Weight loss after RYGB appears to be significant and sustainable, especially in the non-super-obese. Co-morbidities are improved, with a substantial number in remission a decade later. Nutritional deficiencies are almost universal. Copyright © 2016 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

20 CFR 639.10 - When may notice be extended?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false When may notice be extended? 639.10 Section... ADJUSTMENT AND RETRAINING NOTIFICATION § 639.10 When may notice be extended? Additional notice is required when the date or schedule of dates of a planned plant closing or mass layoff is extended beyond the...

20 CFR 639.10 - When may notice be extended?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 3 2014-04-01 2014-04-01 false When may notice be extended? 639.10 Section... ADJUSTMENT AND RETRAINING NOTIFICATION § 639.10 When may notice be extended? Additional notice is required when the date or schedule of dates of a planned plant closing or mass layoff is extended beyond the...

20 CFR 639.10 - When may notice be extended?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false When may notice be extended? 639.10 Section... ADJUSTMENT AND RETRAINING NOTIFICATION § 639.10 When may notice be extended? Additional notice is required when the date or schedule of dates of a planned plant closing or mass layoff is extended beyond the...

20 CFR 639.10 - When may notice be extended?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 3 2013-04-01 2013-04-01 false When may notice be extended? 639.10 Section... ADJUSTMENT AND RETRAINING NOTIFICATION § 639.10 When may notice be extended? Additional notice is required when the date or schedule of dates of a planned plant closing or mass layoff is extended beyond the...

20 CFR 639.10 - When may notice be extended?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false When may notice be extended? 639.10 Section... ADJUSTMENT AND RETRAINING NOTIFICATION § 639.10 When may notice be extended? Additional notice is required when the date or schedule of dates of a planned plant closing or mass layoff is extended beyond the...

Stress Generation, Avoidance Coping, and Depressive Symptoms: A 10-Year Model

PubMed Central

Holahan, Charles J.; Moos, Rudolf H.; Holahan, Carole K.; Brennan, Penny L.; Schutte, Kathleen K.

2011-01-01

This study examined (a) the role of avoidance coping in prospectively generating both chronic and acute life stressors and (b) the stress-generating role of avoidance coping as a prospective link to future depressive symptoms. Participants were 1,211 late-middle-aged individuals (500 women and 711 men) assessed 3 times over a 10-year period. As predicted, baseline avoidance coping was prospectively associated with both more chronic and more acute life stressors 4 years later. Furthermore, as predicted, these intervening life stressors linked baseline avoidance coping and depressive symptoms 10 years later, controlling for the influence of initial depressive symptoms. These findings broaden knowledge about the stress-generation process and elucidate a key mechanism through which avoidance coping is linked to depressive symptoms. PMID:16173853

Preteen insulin levels interact with caloric intake to predict increases in obesity at ages 18 to 19 years: a 10-year prospective study of black and white girls.

PubMed

Morrison, John A; Glueck, Charles J; Wang, Ping

2010-05-01

We evaluated the associations of teenage insulin and adolescent diet with 10-year weight gain in an analysis sample of black and white girls matched for pubertal stage, body mass index (BMI) (or fat mass), and insulin at ages 9 to 10 years. We hypothesized that preteen insulin and insulin resistance would interact with dietary factors to positively predict increases in BMI. Furthermore, we hypothesized that increased insulin and insulin resistance, interacting with higher caloric intake during adolescence, would lead to greater increments in BMI in black girls than in white girls. Prospective 10-year follow-up was performed on 215 pairs of black and white schoolgirls matched at baseline by BMI (or fat mass), insulin, and pubertal stage, with repeated measures of body habitus, insulin, and dietary intake. When matched for BMI, black girls had higher fat-free mass and white girls had higher fat mass at ages 9 to 10 years. Black-white differences in caloric intake were not significant at ages 9 to 10 years, but black girls consumed more calories at age 19 years. Black girls consumed a greater percentage of calories from fat throughout. At age 19 years, black girls had higher BMI, fat mass index, and insulin. When matched at ages 9 to 10 years for fat mass, black girls were heavier, had higher BMI, and had greater fat-free mass. By ages 18 to 19 years, black girls continued to have higher BMI, but had accrued higher fat mass and a higher percentage of body fat. By stepwise multiple regression, 10-year increases in BMI were predicted by ages 9 to 10 years BMI, 10-year change in insulin, and a 3-way interaction between ages 9 to 10 years insulin, adolescent caloric intake, and race (higher in black girls) (all Ps < .0001). Insulin at ages 9 to 10 years interacts with caloric intake to increase BMI by age 19 years. There appear to be intrinsic black-white metabolic differences that lead to greater gains in fat during adolescence in black girls. Evaluating BMI and insulin

Life expectancy in a birth cohort of Boxers followed up from weaning to 10 years of age.

PubMed

van Hagen, Marjan A E; Ducro, Bart J; van den Broek, Jan; Knol, Bart W

2005-09-01

To determine mortality rate over time, risk factors for death, and heritability of life expectancy in Boxers. 1,733 purebred Boxers born in The Netherlands between January 1994 and March 1995. Dogs were followed up from weaning (ie, 49 days of age) to 10 years of age through use of a written questionnaire sent to owners every 6 months. Mortality rate over time, risk factors potentially associated with death, and heritability of life expectancy were examined by use of a proportional hazards model based on the Weibull distribution. stimated mortality rate during the 10-year study period for this birth cohort of Boxers was 45%. The probability of surviving to 5 years of age was 88%; the probability of surviving to 10 years of age was 55%. Estimated effective heritability of life expectancy was 0.076, meaning that in this population, an estimated 76% of the observed variation in life expectancy could be attributed to genetic differences among dogs that were passed from parents to their offspring. Results suggest that cumulative incidence of death from weaning to 10 years of age among this birth cohort of Boxers was 45%. The estimated heritability of life expectancy suggested that life expectancy can be improved by use of selective breeding.

The Brunhes/Matuyama polarity transition recorded as Be-10 flux changes in deep-sea sediments

NASA Astrophysics Data System (ADS)

Suganuma, Y.; Yokoyama, Y.; Yamazaki, T.

2008-12-01

Fluxes of meteoric cosmogenic radionuclide, Be-10, is thought to be varied due to changes of incoming comic-ray flux modulated by geomagnetic field intensity variation. Enhanced production rate of the nuclides during a geomagnetic polarity transition period is expected as a result of the low dipole field strength. We therefore measured Be-10 concentrations in deep-sea sediments including the Brunhes/Matuyama geomagnetic polarity transition to reconstruct the detailed structures of the geomagnetic field behavior. A piston core, MD982187 was taken from the West Caroline Basin, the western equatorial Pacific Ocean, during the IMAGES IV campaign. The water depth of the site of MD982187 core is about 4600 m, which is close to the carbonate compensation depth (CCD) in this area at present (Berger et al., 1976). Measurement of Be-10 was conducted using the accelerator mass spectrometry (AMS) of the University of Tokyo, Japan. The result shows significant increase of Be-10 concentration during the polarity transition, indicating that the geomagnetic field intensity was low during this interval. In detail, well-defined double highs of Be-10 concentration are recognized. These highs are thought to correspond to the B/M polarity boundary and the "precursor" event, 15 kyr before the M/B boundary (e.g., Hartl and Tauxe, 1996; Singer et al., 2005), respectively. This feature is very similar to the relative paleointensity record of MR982187 core by Yamazaki and Oda (2005) and other published relative paleointensity records of the Brunhes/Matuyama geomagnetic polarity transition, indicating that Be-10 concentration of the deep-sea sedimentary sequence well records the variation of the geomagnetic field intensity. However, ca. 18 cm of clear depth offset between the Be-10 concentration and the relative paleointensity record was observed from the same sedimentary sequence of MR982187 core. This indicates that the relative paleointensity record of MR982187 core is offset by ca. 18 cm

Attitudes to HPV Vaccination among Parents of Children Aged 10 to 13 Years.

PubMed

Seven, Memnun; Güvenç, Gülten; Şahin, Eda; Akyüz, Aygül

2015-10-01

This study aimed to determine the willingness of parents to allow their sons and/or daughters aged 10-13 years to be vaccinated for human papillomavirus (HPV). This was a descriptive study conducted in an elementary school to recruit students' parents into the study. The sample consisted of 368 (69.1%) parents of children aged 10-13 years who were willing to participate in the study as a couple. Questionnaire-based data were collected from the couples. Prior information regarding HPV and vaccination and the opinions of parents of children aged 10-13 about HPV vaccination for their daughter or son. Only 26.9% of mothers and 25.0% of fathers claimed to be aware of HPV, and only 24.5% of mothers and 21.2% of fathers claimed to be aware of its vaccine. If the vaccine were available in Turkey, 21.6% of mothers and 22.4% of fathers would be willing to vaccinate their sons; although the vaccine for girls is available in Turkey, only 14.4% of mothers and 15.5% of fathers were willing to vaccinate their daughters. Few participants reported knowing about the HPV vaccine, while far fewer intended to vaccinate their daughters and sons against the infection. Both males and females should be informed about HPV and its vaccine, and initiatives to increase both awareness and the information of health care professionals should be encouraged. Copyright © 2015 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

A new standardized treadmill walking test requiring low motor skills in children aged 4-10 years.

PubMed

Wäffler-Kammermann, Nathalie; Lacorcia, Ruth Stauffer; Wettstein, Markus; Radlinger, Lorenz; Frey, Urs

2008-02-01

Exercise intolerance may be reported by parents of young children with respiratory diseases. There is, however, a lack of standardized exercise protocols which allow verification of these reports especially in younger children. Consequently the aims of this pilot study were to develop a standardized treadmill walking test for children aged 4-10 years demanding low sensorimotor skills and achieving high physical exhaustion. In a prospective experimental cross sectional pilot study, 33 healthy Caucasian children were separated into three groups: G1 (4-6 years, n = 10), G2 (7-8 years, n = 12), and G3 (9-10 years, n = 11). Children performed the treadmill walking test with increasing exercise levels up to peak condition with maximal exhaustion. Gas exchange, heart rate, and lactate were measured during the test, spirometry before and after. Parameters were statistically calculated at all exercise levels as well as at 2 and 4 mmol/L lactate level for group differences (Kruskal-Wallis H-test, alpha = 0.05; post hoc: Mann-Whitney U-test with Bonferroni correction alpha = 0.05/n) and test-retest differences (Wilcoxon-rank-sum test) with SPSS. The treadmill walking test could be demonstrated to be feasible with a good repeatability within groups for most of the parameters. All children achieved a high exhaustion level. At peak level under exhaustion condition only the absolute VO2 and VCO2 differed significantly between age groups. In conclusion this newly designed treadmill walking test indicates a good feasibility, safety, and repeatability. It suggests the potential usefulness of exercise capacity monitoring for children aged from early 4 to 10 years. Various applications and test modifications will be investigated in further studies. Copyright 2007 Wiley-Liss, Inc.

Men's Aggression toward Women: A 10-Year Panel Study

ERIC Educational Resources Information Center

Kim, Hyoun K.; Laurent, Heidemarie K.; Capaldi, Deborah M.; Feingold, Alan

2008-01-01

The present study examined the longitudinal course of men's physical and psychological aggression toward a partner across 10 years, using a community sample of young couples (N = 194) from at-risk backgrounds. Findings indicated that men's aggression decreased over time and that women's antisocial behavior and depressive symptoms predicted changes…

Lost productive life years caused by chronic conditions in Australians aged 45-64 years, 2010-2030.

PubMed

Schofield, Deborah J; Shrestha, Rupendra N; Cunich, Michelle; Tanton, Robert; Kelly, Simon; Passey, Megan E; Veerman, Lennert J

2015-09-21

To estimate (1) productive life years (PLYs) lost because of chronic conditions in Australians aged 45-64 years from 2010 to 2030, and (2) the impact of this loss on gross domestic product (GDP) over the same period. A microsimulation model, Health&WealthMOD2030, was used to project lost PLYs caused by chronic conditions from 2010 to 2030. The base population consisted of respondents aged 45-64 years to the Australian Bureau of Statistics Survey of Disability, Ageing and Carers 2003 and 2009. The national impact of lost PLYs was assessed with Treasury's GDP equation. Lost PLYs due to chronic disease at 2010, 2015, 2020, 2025 and 2030 (ie, whole life years lost because of chronic disease); the national impact of lost PLYs at the same time points (GDP loss caused by PLYs); the effects of population growth, labour force trends and chronic disease trends on lost PLYs and GDP at each time point. Using Health&WealthMOD2030, we estimated a loss of 347,000 PLYs in 2010; this was projected to increase to 459,000 in 2030 (32.28% increase over 20 years). The leading chronic conditions associated with premature exits from the labour force were back problems, arthritis and mental and behavioural problems. The percentage increase in the number of PLYs lost by those aged 45-64 years was greater than that of population growth for this age group (32.28% v 27.80%). The strongest driver of the increase in lost PLYs was population growth (accounting for 89.18% of the increase), followed by chronic condition trends (8.28%). Our study estimates an increase of 112 000 lost PLYs caused by chronic illness in older workers in Australia between 2010 and 2030, with the most rapid growth projected to occur in men aged 55-59 years and in women aged 60-64 years. The national impact of this lost labour force participation on GDP was estimated to be $37.79 billion in 2010, increasing to $63.73 billion in 2030.

Studies of Be migration in the JET tokamak using AMS with 10Be marker

NASA Astrophysics Data System (ADS)

Bykov, I.; Bergsåker, H.; Possnert, G.; Zhou, Y.; Heinola, K.; Pettersson, J.; Conroy, S.; Likonen, J.; Petersson, P.; Widdowson, A.

2016-03-01

The JET tokamak is operated with beryllium limiter tiles in the main chamber and tungsten coated carbon fiber composite tiles and solid W tiles in the divertor. One important issue is how wall materials are migrating during plasma operation. To study beryllium redistribution in the main chamber and in the divertor, a 10Be enriched limiter tile was installed prior to plasma operations in 2011-2012. Methods to take surface samples have been developed, an abrasive method for bulk Be tiles in the main chamber, which permits reuse of the tiles, and leaching with hot HCl to remove all Be deposited at W coated surfaces in the divertor. Quantitative analysis of the total amount of Be in cm2 sized samples was made with inductively coupled plasma atomic emission spectroscopy (ICP-AES). The 10Be/9Be ratio in the samples was measured with accelerator mass spectrometry (AMS). The experimental setup and methods are described in detail, including sample preparation, measures to eliminate contributions in AMS from the 10B isobar, possible activation due to plasma generated neutrons and effects of diffusive isotope mixing. For the first time marker concentrations are measured in the divertor deposits. They are in the range 0.4-1.2% of the source concentration, with moderate poloidal variation.

Inverse association between docosahexaenoic acid and mortality in patients on hemodialysis during over 10 years.

PubMed

Terashima, Yoshihiro; Hamazaki, Kei; Itomura, Miho; Tomita, Shin; Kuroda, Masahiro; Hirata, Hitoshi; Hamazaki, Tomohito; Inadera, Hidekuni

2014-07-01

We have previously conducted a cohort study to investigate n-3 polyunsaturated fatty acids (PUFAs) in red blood cells (RBCs) and risk of all-cause mortality in hemodialysis (HD) patients over 5 years and found that n-3 PUFAs, especially docosahexaenoic acid (DHA), might be an independent predictor of all-cause mortality. In the present study, we extended the study for another 5 years to determine whether DHA levels in RBCs still predict the mortality of HD patients during a 10-year study period. The study cohort consisted of 176 patients (64.1 ± 12.0 [mean ± standard deviation] years of age, 96 men and 80 women) under HD treatment. The fatty acid composition of patients' RBCs was analyzed by gas chromatography. During the study period of 10 years, 97 deaths occurred. After adjustment for 10 confounding factors, the hazard ratio of all-cause mortality of the HD patients in the highest DHA tertile (>8.1%) was 0.52 (95% confidence interval 0.30-0.91) compared with those in the lowest DHA tertile (<7.2%). However, other n-3 PUFAs such as eicosapentaenoic acid and docosapentaenoic acid (n-3) did not reveal any significant correlations. The level of DHA in RBCs could be an independent predictor of all-cause mortality in HD patients even during a long period of follow-up. © 2014 International Society for Hemodialysis.

A longitudinal study of grapheme-color synesthesia in childhood: 6/7 years to 10/11 years

PubMed Central

Simner, Julia; Bain, Angela E.

2013-01-01

Grapheme-color synesthesia is a condition characterized by enduring and consistent associations between letter/digits and colors. This study is the continuation of longitudinal research begun by Simner et al. (2009) which aimed to explore the development of this condition in real time within a childhood population. In that earlier study we randomly sampled over 600 children and tested them aged 6/7 and 7/8 years. We identified the child synesthetes within that cohort and measured their development over 1 year, in comparison to a group of non-synesthetic children with both average and superior memories. We were able to show the beginnings of a developmental progression in which synesthetic associations (e.g., A = red) mature over time from relatively chaotic pairings into a system of fixed consistent associations. In the current study we return to this same population three years later when participants are now 10/11 years. We used the same paired-association memory task to determine the synesthetic status of our participants and to also establish synesthetes' inventories of grapheme-color associations. We compared their inventories to those from age 6/7 and 7/8 years to examine how synesthesia matures over time. Together with earlier findings, our study shows that grapheme-color synesthesia emerges with a protracted trajectory, with 34% of letters/digits fixed at age 6/7 years, 48% fixed at 7/8 years and 71% fixed at 10/11 years. We also show several cases where synesthesia is not developing in the same time-frame as peers, either because it has died out at an older age, or because it was slower to develop than other cases. Our study paints the first picture of the emergence of synesthesia in real-time over four years within a randomly sampled population of child synesthetes. PMID:24312035

10-year evaluation of train accidents.

PubMed

Akkaş, Meltem; Ay, Didem; Metin Aksu, Nalan; Günalp, Müge

2011-09-01

Although less frequent than automobile accidents, train accidents have a major impact on victims' lives. Records of patients older than 16 years of age admitted to the Adult Emergency Department of Hacettepe University Medical Center due to train accidents were retrospectively evaluated. 44 patients (30 males, 14 females) with a mean age of 31.8±11.4 years were included in the study. The majority of the accidents occurred during commuting hours. 37 patients were discharged, 22 of them from the emergency department. The mortality rate was 7/44 (16%). Overall mean Revised Trauma Score (RTS) was 10.5 (3 in deaths and 11.9 in survivors). In 5 patients, the cause of death was pelvic trauma leading to major vascular injury and lower limb amputation. In 1 patient, thorax and abdomen trauma and in 1 patient head injury were the causes of mortality. Primary risk factors for mortality were alcohol intoxication (100%), cardiopulmonary resuscitation on admittance (100%), recurrent suicide attempt (75%), presence of psychiatric illness (60%), and low RTS. In this study, most train accidents causing minor injuries were due to falling from the train prior to acceleration. Nevertheless, train accidents led to a mortality rate of 16% and morbidity rate of 37%. These findings draw attention to the importance of developing preventive strategies.

Gardening practices in a rural village in South Africa 10 years after completion of a home garden project.

PubMed

Zimpita, Tisungeni; Biggs, Chara; Faber, Mieke

2015-03-01

Few studies have documented whether the behavior changes produced by home garden projects have been maintained after completion of the projects. To determine the benefits and challenges affecting production and consumption of β-carotene-rich vegetables and fruits in a rural South African village 10 years after completion of a home garden project. This cross-sectional survey assessed gardening practices and household consumption of β-carotene-rich vegetables and fruits using a questionnaire (n = 186). Benefits and challenges affecting production and consumption of β-carotene-rich vegetables and fruits were assessed through focus group discussions. Thirty-nine percent of the households currently planted β-carotene-rich vegetables and fruits. Major challenges included lack of fencing, animals eating crops, and lack or shortage of water. Planting materials for β-carotene-rich vegetables were sourced from the community nursery, while papaya was grown from its own seed. Shops were the most likely alternative sources of β-carotene-rich vegetables. The frequency of consumption of orange-fleshed sweet potato, butternut, spinach, and papaya when in season differed significantly, with households planting β-carotene-rich vegetables and fruits having more frequent consumption than households not planting these vegetables and fruits. Households planting β-carotene-rich vegetables and fruits were perceived as "well-to-do" and "healthy" households and as "givers". This study showed that 10 years after the endline evaluation of a home garden project, approximately one-third of the households in the village planted β-carotene-rich vegetables and fruits, which is very similar to the proportion at project completion and a postintervention study that was done 6 years later, despite various challenges, indicating that the practice of planting these vegetables and fruits was continued over the years.

Twenty-million-year relationship between mammalian diversity and primary productivity

PubMed Central

Fritz, Susanne A.; Eronen, Jussi T.; Schnitzler, Jan; Hof, Christian; Janis, Christine M.; Mulch, Andreas; Böhning-Gaese, Katrin; Graham, Catherine H.

2016-01-01

At global and regional scales, primary productivity strongly correlates with richness patterns of extant animals across space, suggesting that resource availability and climatic conditions drive patterns of diversity. However, the existence and consistency of such diversity–productivity relationships through geological history is unclear. Here we provide a comprehensive quantitative test of the diversity–productivity relationship for terrestrial large mammals through time across broad temporal and spatial scales. We combine >14,000 occurrences for 690 fossil genera through the Neogene (23–1.8 Mya) with regional estimates of primary productivity from fossil plant communities in North America and Europe. We show a significant positive diversity–productivity relationship through the 20-million-year record, providing evidence on unprecedented spatial and temporal scales that this relationship is a general pattern in the ecology and paleo-ecology of our planet. Further, we discover that genus richness today does not match the fossil relationship, suggesting that a combination of human impacts and Pleistocene climate variability has modified the 20-million-year ecological relationship by strongly reducing primary productivity and driving many mammalian species into decline or to extinction. PMID:27621451

Can the Results of Biodiversity-Ecosystem Productivity Studies Be Translated to Bioenergy Production?

DOE PAGES

Dickson, Timothy L.; Gross, Katherine L.

2015-09-11

Biodiversity experiments show that increases in plant diversity can lead to greater biomass production, and some researchers suggest that high diversity plantings should be used for bioenergy production. However, many methods used in past biodiversity experiments are impractical for bioenergy plantings. For example, biodiversity experiments often use intensive management such as hand weeding to maintain low diversity plantings and exclude unplanted species, but this would not be done for bioenergy plantings. Also, biodiversity experiments generally use high seeding densities that would be too expensive for bioenergy plantings. Here we report the effects of biodiversity on biomass production from two studiesmore » of more realistic bioenergy crop plantings in southern Michigan, USA. One study involved comparing production between switchgrass (Panicum virgatum) monocultures and species-rich prairie plantings on private farm fields that were managed similarly to bioenergy plantings. The other study was an experiment where switchgrass was planted in monoculture and in combination with increasingly species-rich native prairie mixtures. Overall, we found that bioenergy plantings with higher species richness did not produce more biomass than switchgrass monocultures. The lack of a positive relationship between planted species richness and production in our studies may be due to several factors. Non-planted species (weeds) were not removed from our studies and these non-planted species may have competed with planted species and also prevented realized species richness from equaling planted species richness. Also, we found that low seeding density of individual species limited the biomass production of these individual species. Finally, production in future bioenergy plantings with high species richness may be increased by using a high density of inexpensive seed from switchgrass and other highly productive species, and future efforts to translate the results of

Can the Results of Biodiversity-Ecosystem Productivity Studies Be Translated to Bioenergy Production?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dickson, Timothy L.; Gross, Katherine L.

Biodiversity experiments show that increases in plant diversity can lead to greater biomass production, and some researchers suggest that high diversity plantings should be used for bioenergy production. However, many methods used in past biodiversity experiments are impractical for bioenergy plantings. For example, biodiversity experiments often use intensive management such as hand weeding to maintain low diversity plantings and exclude unplanted species, but this would not be done for bioenergy plantings. Also, biodiversity experiments generally use high seeding densities that would be too expensive for bioenergy plantings. Here we report the effects of biodiversity on biomass production from two studiesmore » of more realistic bioenergy crop plantings in southern Michigan, USA. One study involved comparing production between switchgrass (Panicum virgatum) monocultures and species-rich prairie plantings on private farm fields that were managed similarly to bioenergy plantings. The other study was an experiment where switchgrass was planted in monoculture and in combination with increasingly species-rich native prairie mixtures. Overall, we found that bioenergy plantings with higher species richness did not produce more biomass than switchgrass monocultures. The lack of a positive relationship between planted species richness and production in our studies may be due to several factors. Non-planted species (weeds) were not removed from our studies and these non-planted species may have competed with planted species and also prevented realized species richness from equaling planted species richness. Also, we found that low seeding density of individual species limited the biomass production of these individual species. Finally, production in future bioenergy plantings with high species richness may be increased by using a high density of inexpensive seed from switchgrass and other highly productive species, and future efforts to translate the results of

25 CFR 309.10 - What are some sample categories and examples of Indian products?

Code of Federal Regulations, 2011 CFR

2011-04-01

... products? 309.10 Section 309.10 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR PROTECTION OF INDIAN ARTS AND CRAFTS PRODUCTS § 309.10 What are some sample categories and examples of Indian.... Additionally, although the Indian Arts and Crafts Act of 1990 and the Indian Arts and Crafts Enforcement Act of...

25 CFR 309.10 - What are some sample categories and examples of Indian products?

Code of Federal Regulations, 2010 CFR

2010-04-01

... products? 309.10 Section 309.10 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR PROTECTION OF INDIAN ARTS AND CRAFTS PRODUCTS § 309.10 What are some sample categories and examples of Indian.... Additionally, although the Indian Arts and Crafts Act of 1990 and the Indian Arts and Crafts Enforcement Act of...

Tennessee long-range transportation plan : 10-year strategic investments program

DOT National Transportation Integrated Search

2005-12-01

The 10-Year Strategic Investments Program report identifies proposed spending priorities and policy initiatives that will address many of Tennessees transportation needs and help implement the states new Long-Range Transportation Plan (LRTP) ov...

41Ca, 14C and 10Be concentrations in coral sand from the Bikini atoll.

PubMed

Lachner, Johannes; Christl, Marcus; Alfimov, Vasily; Hajdas, Irka; Kubik, Peter W; Schulze-König, Tim; Wacker, Lukas; Synal, Hans-Arno

2014-03-01

Activation measurements of materials exposed to nuclear bomb explosions are widely used to reconstruct the neutron flux for retrospective dosimetry. In this study the applicability of coral CaCO3 as a biogenic neutron fluence dosimeter is tested. The long-lived radioisotopes (41)Ca, (14)C and (10)Be, which had been produced in nuclear bomb explosions, are measured in several coral sand samples from the Bikini atoll at the 600 kV and 200 kV AMS facilities of ETH Zurich. Elevated concentrations of all studied isotopes are found in a sample from the crater that was initially formed by the high-yield nuclear explosion Castle Bravo in 1954 and that had been used as site for several tests afterward. The observed (14)C concentration is considered too large to originate from neutron irradiation of CaCO3 alone. The relatively low concentration of (10)Be found in the crater sample indicates that production of (10)Be during nuclear bomb testing is generally minor. A simple neutron fluence reconstruction is performed on basis of the (41)Ca/(40)Ca ratio. Copyright © 2013 Elsevier Ltd. All rights reserved.

24 CFR 203.203 - Issuance and nature of insured 10-year protection plans.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Issuance and nature of insured 10-year protection plans. 203.203 Section 203.203 Housing and Urban Development Regulations Relating to... Underwriting Procedures Insured Ten-Year Protection Plans (plan) § 203.203 Issuance and nature of insured 10...

24 CFR 203.203 - Issuance and nature of insured 10-year protection plans.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Issuance and nature of insured 10-year protection plans. 203.203 Section 203.203 Housing and Urban Development Regulations Relating to... Underwriting Procedures Insured Ten-Year Protection Plans (plan) § 203.203 Issuance and nature of insured 10...

24 CFR 203.203 - Issuance and nature of insured 10-year protection plans.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Issuance and nature of insured 10-year protection plans. 203.203 Section 203.203 Housing and Urban Development Regulations Relating to... Underwriting Procedures Insured Ten-Year Protection Plans (plan) § 203.203 Issuance and nature of insured 10...

24 CFR 203.203 - Issuance and nature of insured 10-year protection plans.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Issuance and nature of insured 10-year protection plans. 203.203 Section 203.203 Housing and Urban Development Regulations Relating to... Underwriting Procedures Insured Ten-Year Protection Plans (plan) § 203.203 Issuance and nature of insured 10...

24 CFR 203.203 - Issuance and nature of insured 10-year protection plans.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Issuance and nature of insured 10-year protection plans. 203.203 Section 203.203 Housing and Urban Development Regulations Relating to... Underwriting Procedures Insured Ten-Year Protection Plans (plan) § 203.203 Issuance and nature of insured 10...

Prostate-specific antigen (PSA) testing of men in UK general practice: a 10-year longitudinal cohort study.

PubMed

Young, Grace J; Harrison, Sean; Turner, Emma L; Walsh, Eleanor I; Oliver, Steven E; Ben-Shlomo, Yoav; Evans, Simon; Lane, J Athene; Neal, David E; Hamdy, Freddie C; Donovan, Jenny L; Martin, Richard M; Metcalfe, Chris

2017-10-30

Cross-sectional studies suggest that around 6% of men undergo prostate-specific antigen (PSA) testing each year in UK general practice (GP). This longitudinal study aims to determine the cumulative testing pattern of men over a 10-year period and whether this testing can be considered equivalent to screening for prostate cancer (PCa). Patient-level data on PSA tests, biopsies and PCa diagnoses were obtained from the UK Clinical Practice Research Datalink (CPRD) for the years 2002 to 2011. The cumulative risks of PSA testing and of being diagnosed with PCa were estimated for the 10-year study period. Associations of a man's age, region and index of multiple deprivation with the cumulative risk of PSA testing and PCa diagnosis were investigated. Rates of biopsy and diagnosis, following a high test result, were compared with those from the programme of PSA testing in the Prostate Testing for Cancer and Treatment (ProtecT) study. The 10-year risk of exposure to at least one PSA test in men aged 45 to 69 years in UK GP was 39.2% (95% CI 39.0 to 39.4%). The age-specific risks ranged from 25.2% for men aged 45-49 years to 53.0% for men aged 65-69 years (p for trend <0.001). For those with a PSA level ≥3, a test in UK GP was less likely to result in a biopsy (6%) and/or diagnosis of PCa (15%) compared with ProtecT study participants (85% and 34%, respectively). A high proportion of men aged 45-69 years undergo PSA tests in UK GP: 39% over a 10-year period. A high proportion of these tests appear to be for the investigation of lower urinary tract symptoms and not screening for PCa. ISRCTN20141297,NCT02044172. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Prostate-specific antigen (PSA) testing of men in UK general practice: a 10-year longitudinal cohort study

PubMed Central

Young, Grace J; Harrison, Sean; Turner, Emma L; Walsh, Eleanor I; Oliver, Steven E; Ben-Shlomo, Yoav; Evans, Simon; Lane, J Athene; Neal, David E; Hamdy, Freddie C; Donovan, Jenny L; Martin, Richard M; Metcalfe, Chris

2017-01-01

Objectives Cross-sectional studies suggest that around 6% of men undergo prostate-specific antigen (PSA) testing each year in UK general practice (GP). This longitudinal study aims to determine the cumulative testing pattern of men over a 10-year period and whether this testing can be considered equivalent to screening for prostate cancer (PCa). Setting, participants and outcome measures Patient-level data on PSA tests, biopsies and PCa diagnoses were obtained from the UK Clinical Practice Research Datalink (CPRD) for the years 2002 to 2011. The cumulative risks of PSA testing and of being diagnosed with PCa were estimated for the 10-year study period. Associations of a man’s age, region and index of multiple deprivation with the cumulative risk of PSA testing and PCa diagnosis were investigated. Rates of biopsy and diagnosis, following a high test result, were compared with those from the programme of PSA testing in the Prostate Testing for Cancer and Treatment (ProtecT) study. Results The 10-year risk of exposure to at least one PSA test in men aged 45 to 69 years in UK GP was 39.2% (95% CI 39.0 to 39.4%). The age-specific risks ranged from 25.2% for men aged 45–49 years to 53.0% for men aged 65–69 years (p for trend <0.001). For those with a PSA level ≥3, a test in UK GP was less likely to result in a biopsy (6%) and/or diagnosis of PCa (15%) compared with ProtecT study participants (85% and 34%, respectively). Conclusion A high proportion of men aged 45–69 years undergo PSA tests in UK GP: 39% over a 10-year period. A high proportion of these tests appear to be for the investigation of lower urinary tract symptoms and not screening for PCa. Trial registration number ISRCTN20141297, NCT02044172. PMID:29084797

Guidance for Product Category Rule Development, Version 1.0

EPA Science Inventory

Environmental claims based on life cycle assessment (LCA) can provide quantitative, full life cycle information on products in a format that can permit comparisons and thereby inform purchasing decisions. In recent years, a number of standards and guides have emerged for making b...

Dollars and sense: Mitigating budget risk for ICD-10.

PubMed

Newell, Lucy Mancini; DeSilva, Joseph J

2013-02-01

The extended deadline for ICD-10 implementation is time that should not be wasted. Healthcare leaders should keep three things in mind: CFOs should approach the effort knowing the costs of ICD-10 implementation will be high and spread over multiple budget years. Training, productivity, and contractual issues are among key areas that will be challenged by ICD-10 implementation. Healthcare finance leaders should work to improve cash-on-hand and cash reserves prior to the ICD-10 deadline to ensure liquidity post-compliance.