Ciarka, Agnieszka; Edwards, Leah; Nilsson, Johan; Stehlik, Josef; Lund, Lars H
2017-03-15
Numerous cohort analyses suggest rapidly increasing use of mechanical circulatory support (MCS) as a bridge to heart transplantation (HTx), but the role of age in selection for MCS remains unknown. We assessed adult HTx in the International Society for Heart And Lung Transplantation Registry between 2005 and 2013 and we determined MCS use by recipient age group and transplant year. Multivariable logistic regression models were constructed to identify variables associated with continuous flow (CF) left ventricular assist device (LVAD) use within each age group. Among 16,480 HTx recipients the percentage of overall MCS use increased from 23% to 38%, 21% to 41%, and 17% to 42% in age groups 18-39 years, 40-59 years and over 60 years, respectively. This effect was mainly due to an increase in CF LVAD use and primarily in HTx recipients aged over 60. In multivariable analyses, male gender and blood group O were significantly associated with CF LVAD use in all age groups. Bridge to transplant MCS use increased dramatically between 2005 and 2013 primarily due to increased use of CF LVAD and primarily in higher ages. Pre-HTx CF LVAD use was more frequent in men and blood group O. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Tandem mass spectrometry spectral libraries and library searching.
Deutsch, Eric W
2011-01-01
Spectral library searching in the field of proteomics has been gaining visibility and use in the last few years, primarily due to the expansion of public proteomics data repositories and the large spectral libraries that can be generated from them. Spectral library searching has several advantages over conventional sequence searching: it is generally much faster, and has higher specificity and sensitivity. The speed increase is primarily, due to having a smaller, fully indexable search space of real spectra that are known to be observable. The increase in specificity and sensitivity is primarily due to the ability of a search engine to utilize the known intensities of the fragment ions, rather than just comparing with theoretical spectra as is done with sequence searching. The main disadvantage of spectral library searching is that one can only identify peptide ions that have been seen before and are stored in the spectral library. In this chapter, an overview of spectral library searching and the libraries currently available are presented.
Butterman, W.C.; McCartan, L.; Morse, D.E.; Sibley, S.F.
1999-01-01
The US coal industry had a good year in 1998, setting another production record of 1.015 Gt (1.12 billion st), an increase of 2.6% from 1997. The increase was led by coal use for electricity generation, responding primarily to a substantial decline in hydroelectric generation. Year-end coal stocks at electric utilities swelled in 1998 for the first time in four years due to unseasonably mild fall and winter weather.
A comparison of state policies for complying with the endangered species act.
DOT National Transportation Integrated Search
2007-10-01
In recent years the number of biological assessments (BAs) for the presence of endangered species conducted by KYTC has risen significantly. This was primarily due to new/additional restrictions imposed by the United States Fish and Wildlife Service ...
Testing and Evaluation of Large Stone Mixes Using Marshall Mix Design Procedures
DOT National Transportation Integrated Search
1989-11-01
Premature rutting of heavy duty asphalt pavements has been increasingly experienced in recent years primarily due to high pressure truck tires and increased wheel loads. Many asphalt technologists believe that the use of large size stone (maximum siz...
Summer moisture of forest fire fuels in Oregon and Washington in 1948 and previous years.
William G. Morris
1948-01-01
The forest fire season of 1948 in Oregon and Washington was regarded by fire suppression agencies as the most favorable for many years. The number of fires started and area burned were, in general, less than for many years. On the national forests the number of fires was the least since 1912 and the acreage burned was the least ever recorded. Was this primarily due to...
Oakton Community College Annual Budget, Fiscal Year 1998-1999, Community College District 535.
ERIC Educational Resources Information Center
Oakton Community Coll., Des Plaines, IL.
This report provides the annual budget for Oakton (Illinois) Community College's fiscal year 1998-1999. The budget contains a total of $59,751,098 in revenues and $61,697,515 in expenditures, a 5.29% increase. The deficit is due primarily to remodeling and outfitting of facilities at one of the campuses and deployment of a computing system for the…
Alexander J. Michalek; Brian Roy Lockhart; Thomas J. Dean; Bobby D. Keeland; John W. McCoy
2002-01-01
Interest in restoring bottomland hardwoods on abandoned agricultural fields has gained considerably over the past 15 years, due primarily to federal cost-share programs such as the Conservation Reserve Program and the Wetlands Reserve Program. While a variety of artificial regeneration techniques are available to afforest these lands, none have met with consistently...
HOME TREATMENT DEVICES - MICROBIOLOGY OF POINT OF USE AND POINT OF ENTRY DEVICES
Consumer concerns over the quality of their drinking water have increased steadily over the past 15-20 years. This is primarily due to the perception of consumers, significantly influenced by news media reports, that contaminants (chemical and microbiological) in municipal drinki...
Study of the Sustainability of an Integrated Ecosystem with Energy Considerations
In recent years, there has been a growing interest in the study of sustainability. This is primarily due to the realization that continuous sustenance of the current ecosystem is possible only if we carefully understand the implications of the policies that are being practiced. I...
ASSESSING THE CONDITION OF THE NATION'S COASTAL WATERS
EPA's Office of Water submits a National Water Quality Inventory every 2 years to Congress prepared under Section 305(b) of the Clean Water Act. The estimate of total estuarine area increased by 49,000 square miles in 1998 primarily due to the addition of Alaska. This resulted in...
This manuscript describes two years of field research on ground-nesting songbird species at Zumwalt Prairie Reserve, northeastern Oregon, USA. Cattle-grazing has long been suspected in declines of ground-nesting songbirds in grazed grassland, primarily due to increased trampling...
Genetic Changes in Fluctuating Vole Populations: Selective VS. Nonselective Forces
Gaines, Michael S.; Whittam, Thomas S.
1980-01-01
The Lewontin-Krakauer test for selective neutrality of polymorphisms was applied to temporal variation in gene frequency at five electrophoretic loci in each of four fluctuating vole populations over a three-year period. The results indicate that changes in gene frequencies were primarily due to nonselective forces. PMID:7021314
Fact Sheet on the Earnings Gap.
ERIC Educational Resources Information Center
Women's Bureau (DOL), Washington, DC.
A comparison of median income since 1955 shows that the salary differential between men and women has increased in recent years. Although this is due primarily to the over-representation of women in low-skilled, low-paying jobs, even within the same occupations men are better paid. Salary comparisons for professional occupations show differentials…
Developmental Trajectories of Young Girls with Fragile X Syndrome
ERIC Educational Resources Information Center
Hatton, Deborah D.; Wheeler, Anne; Sideris, John; Sullivan, Kelly; Reichardt, Alison; Roberts, Jane; Clark, Renee; Bailey, Donald B., Jr.
2009-01-01
To describe the early phenotype of girls with full mutation fragile X, we used 54 observations of 15 girls between the ages of 6 months and 9 years to examine developmental trajectories as measured by the Battelle Development Inventory. In this sample, autistic behavior was associated with poorer developmental outcomes, primarily due to…
USDA-ARS?s Scientific Manuscript database
In the past six years, pomegranate (POM) cultivation has become a popular commercial crop in San Joaquin Valley, California. The rising demand for this permanent crop is primarily due to POM juice high nutritional and antioxidants properties. In addition, it has been found POM trees are drought tole...
2014-01-01
citizens at home, to combating insurgents abroad. Providing Advanced Technologies The Army’s Science and Technology (S&T) investments support Army...Construction 29,892,790 33,309,504 (Less: Earned Revenue) $ (14,868,782) $ (14,584,858) Net Cost before Losses/(Gains) from Actuarial Assumption Changes for...Benefits consist of various employee actuarial liabilities not due and payable during the current fiscal year. These liabilities consist primarily
Recurrent herpes simplex virus type 2 meningitis in elderly persons.
Davis, Larry E; Guerre, Jenny; Gerstein, Wendy H
2010-06-01
To review the ages of patients with recurrent herpes simplex virus type 2 (HSV-2) meningitis. Case report and literature review back to 1970. Referral Veterans Affairs hospital. Our patient developed his first episode of recurrent HSV-2 meningitis at 78 years of age, 57 years after his only episode of genital herpes simplex infection. Of 223 patients in the literature with recurrent HSV-2 meningitis, 5% occurred in patients older than 60 years and 19% in patients older than 50 years. Although recurrent meningitis due to HSV is primarily seen in young, sexually active adults, a surprising number of episodes of HSV meningitis can develop in older age. Meningitis due to HSV-2 should be in the differential diagnosis of aseptic meningitis in older patients.
Human dirofilariasis due to Dirofilaria repens in southern India.
Kotigadde, Subbannayya; Ramesh, Sathyavathi Alva; Medappa, Kariyappa Thadiangada
2012-01-01
Dirofilariasis is primarily confined to animals such as dogs, cats, foxes and raccoons. Human dirofilariasis is an accidental zoonotic infection acquired through mosquitoes. Human dirofilariasis due to Dirofilaria repens though endemic in Kerala, reports from Karnataka state are rare. We report a case of solitary subcutaneous dirofilariasis of the eyelid due to D. repens in a 47-year-old woman. She presented with periorbital edema. The swelling was soft, cystic with associated tenderness. A thin, white worm was noticed in the lesion and was removed by traction which was subsequently identified to be D. repens.
Human dirofilariasis due to Dirofilaria repens in southern India
Kotigadde, Subbannayya; Ramesh, Sathyavathi Alva; Medappa, Kariyappa Thadiangada
2012-01-01
Dirofilariasis is primarily confined to animals such as dogs, cats, foxes and raccoons. Human dirofilariasis is an accidental zoonotic infection acquired through mosquitoes. Human dirofilariasis due to Dirofilaria repens though endemic in Kerala, reports from Karnataka state are rare. We report a case of solitary subcutaneous dirofilariasis of the eyelid due to D. repens in a 47-year-old woman. She presented with periorbital edema. The swelling was soft, cystic with associated tenderness. A thin, white worm was noticed in the lesion and was removed by traction which was subsequently identified to be D. repens. PMID:23508234
Water Quality Effects of Forest Roads in Bottomland Hardwood Stands
Robert B. Rummer
1999-01-01
Management of bottomland hardwood sites requires adequate access to support forest operations. A study conducted in a bottomland forest in central Georgia has evaluated the effect of forest road design on sediment movement and water quality. Five years of measurement indicate that a conventional crowned road design is a net sink for sediment, primarily due to settling...
Catherine A. Scudieri; Carolyn Hull Sieg; Sally M. Haase; Andrea E. Thode; Stephen S. Sackett
2010-01-01
Southwestern USA ponderosa pine (Pinus ponderosa C. Lawson var. scopulorum Engelm.) forests evolved with frequent surface fires and have changed dramatically over the last century. Overstory tree density has sharply increased while abundance of understory vegetation has declined primarily due to the near cessation of fires. We...
Two Degrees of Separation: Abrupt Climate Change and the Adverse Impact to US National Security
2009-04-01
concentrations of CO2 , CH4 and N2O have increased markedly as a result of human activities since 1750 and now far exceed pre-industrial values...determined from ice cores spanning many thousands of years. The atmospheric concentrations of CO2 and CH4 in 2005 exceed by far the natural range over the...last 650,000 years. Global increases in CO2 concentrations are due primarily to fossil fuel use, with land-use change providing another significant
[Twenty-five years of screening eugenics in Spain].
Mérida Donoso, Salvador
2012-01-01
Over the past 25 years, the incidence of newborns with congenital defects in Spain has fallen by 56.7% primarily due to the practice of "fetal risk" abortion, after prenatal diagnosis. In some cases, such as people with Down syndrome, the strategy involves the removal of 80-90% of those affected in pregnancy. After presenting the techniques used today and statistical data, we will make a reflection about the ethical justification for prenatal diagnosis programs and practice of "eugenic" abortion.
Selective Mutism: A Team Approach to Assessment and Treatment in the School Setting
ERIC Educational Resources Information Center
Ponzurick, Joan M.
2012-01-01
The school nurse plays a pivotal role in the assessment and treatment of selective mutism (SM), a rare disorder found in elementary school children. Due to anxiety, children with SM do not speak in uncomfortable situations, primarily the school setting. Diagnosis of SM is often missed in the formative years because the child does speak at home.…
ERIC Educational Resources Information Center
Lin, Chunn-Ying; Hsieh, Ya-Heng; Chen, Cheng-Hung
2015-01-01
Many Western researchers have found that the gaps in the learning progress between students from different socioeconomic statuses primarily occur due to the accumulated effects of long summer vacations, rather than during the school years. However, it remains to be seen whether these findings can be cross-culturally applied to children in Taiwan.…
The Debt Burden of Bachelor's Degree Recipients. Stats in Brief. NCES 2017-436
ERIC Educational Resources Information Center
Velez, Erin Dunlop; Woo, Jennie H.
2017-01-01
As of May 2013, total outstanding student loan debt in the United States had reached $1.2 trillion, up from $1 trillion fewer than 18 months before. The growth in debt is due primarily to increases in both the rate of borrowing and the average amount borrowed, especially among graduates of 4-year institutions. In 1989-90, about half (51 percent)…
Kieliger, S; Glatz, M; Cozzio, A; Bosshard, P P
2015-08-01
Tinea capitis and tinea faciei are dermatophyte infections of the scalp and glabrous skin of the face affecting mainly prepubertal children. During the past 30 years, a significant increase and a change in the pattern of infectious agents has been noted for tinea capitis. The aim of this study was to determine trends in the current epidemiological situation of tinea capitis and tinea faciei in the Zurich area, Switzerland and adjacent Central and Eastern Switzerland. Consecutive cases diagnosed between 2006 and 2013 were studied retrospectively. A total of 90 tinea capitis and 40 tinea faciei cases were observed. Anthropophilic isolates (primarily Trichophyton violaceum and Microsporum audouinii) accounted for 76% of tinea capitis cases. In contrast, zoophilic isolates (primarily T. interdigitale) were responsible for 73% of tinea faciei cases. The peak incidence in both conditions was in 4-8 year-old children. While the annual number of tinea faciei cases remained stable over the past 8 years, a trend for an increase in T. violaceum-positive tinea capitis has been observed. This was mainly due to patients of African ethnicity. Anthropophilic isolates accounted for three quarters of tinea capitis and one quarter of tinea faciei cases. T. violaceum-positive tinea capitis was primarily linked to patients of African ethnicity. Tinea capitis caused by Microsporum spp. was more refractory to therapy and needed longer treatment than Trichophyton spp.-induced infection. © 2014 European Academy of Dermatology and Venereology.
Helble, Tyler A; Ierley, Glenn R; D'Spain, Gerald L; Martin, Stephen W
2015-01-01
Time difference of arrival (TDOA) methods for acoustically localizing multiple marine mammals have been applied to recorded data from the Navy's Pacific Missile Range Facility in order to localize and track humpback whales. Modifications to established methods were necessary in order to simultaneously track multiple animals on the range faster than real-time and in a fully automated way, while minimizing the number of incorrect localizations. The resulting algorithms were run with no human intervention at computational speeds faster than the data recording speed on over forty days of acoustic recordings from the range, spanning multiple years. Spatial localizations based on correlating sequences of units originating from within the range produce estimates having a standard deviation typically 10 m or less (due primarily to TDOA measurement errors), and a bias of 20 m or less (due primarily to sound speed mismatch). An automated method for associating units to individual whales is presented, enabling automated humpback song analyses to be performed.
ERIC Educational Resources Information Center
Chou, Chin-Cheng
2017-01-01
Elementary school remedial teaching has been promoted for many years in Taiwan but it has primarily been aimed at Chinese and mathematics with little attention being paid to natural sciences. Due to the current shortage of natural science teachers, along with limitations in school budget and manpower, it is difficult to put natural science…
Yoshihara, Toshihiro; Matsumura, Hideyuki; Tsuzaki, Masaharu; Wakamatsu, Takashi; Kobayashi, Takuya; Hashida, Shin-Nosuke; Nagaoka, Toru; Goto, Fumiyuki
2014-12-01
Yearly changes in radiocesium ((137)Cs) contamination, primarily due to the Fukushima accident of March 2011, were observed in the foliar parts of 10 common woody species in Japan (Chamaecyparis obtusa, Cedrus deodara, Pinus densiflora, Cryptomeria japonica, Phyllostachys pubescens, Cinnamomum camphora, Metasequoia glyptostroboides, Prunus × yedoensis, Acer buergerianum, and Aesculus hippocastanum). The samples were obtained from Abiko (approximately 200 km SSW of the Fukushima Dai-ichi Nuclear Power Plant) during each growing season between 2011 and 2013, and the foliar parts were examined based on their year of expansion and location in each trees. The radiocesium concentrations generally decreased with time; however, the concentrations and rates of decrease varied among species, age of foliar parts, and locations. The radiocesium concentrations in the 2012 current-year foliar parts were 29%-220% of those from 2011, while those from 2013 fell to between 14% and 42% of the 2011 values. The net decontamination in the foliage was higher in evergreen species than in deciduous species. The radiocesium concentrations in the upper foliar parts were higher than those in the lower parts particularly in C. japonica. In addition, the radiocesium concentrations were higher in the current-year foliar parts than in the 1-year-old foliar parts, particularly in 2013. Thus, the influence of the direct deposition of the fallout was reduced with time, and the translocation ability of radiocesium from old to new tissues became more influential. Similar to the behavior of potassium in trees, Cs redistribution probably occurred primarily due to internal nutrient translocation mechanisms. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.
Influence of land runoff on rates and agents of bioerosion of coral substrates.
Hutchings, Pat; Peyrot-Clausade, Mireille; Osnorno, Alicia
2005-01-01
Annually large volumes of fresh water laden with sediment are washed down the Daintree River in North Queensland into the Great Barrier Reef lagoon. To investigate the effects of land runoff on bioerosion, samples of recently killed colonies of Porites were laid at 6 sites on a cross shelf transect from Snapper Island at the entrance to the river to Osprey Reef, approximately 328 km from the river mouth out in the Coral Sea. Rates and agents of bioerosion were determined over 4 years and inshore sites exhibited significantly lower rates of total bioerosion than the other sites. Offshore sites experienced high rates of bioerosion primarily due to grazing and internal bioerosion by macroborers such as sponges and bivalves was also important at some of these sites. Inshore sites were covered in heavy layers of silt which inhibited colonization and growth of microborers, primarily algae. This resulted in lower levels of grazing than at offshore sites. However the activity of macroborers (primarily sponges and bivalves) was often high at these sites. The macroboring communities differed between sites and over time and it is hypothesised that these site differences were due to different levels of terrestrial runoff. These results are compared with those from French Polynesia where contaminated terrestrial runoff greatly influenced rates and agents of bioerosion. However other factors such as overfishing may also play an important role in some locations.
Ionospheric chemistry. [minor neutrals and ionized constituents of thermosphere
NASA Technical Reports Server (NTRS)
Torr, D. G.
1979-01-01
This report deals primarily with progress in the chemistry of minor neutrals and ionized constituents of the thermosphere. Significant progress was made over the last few years in quantitative studies of many chemical processes. This success was primarily due to the advent of multiparameter multisatellite programs which permitted accurate simultaneous measurements to be made of many important parameters. In many cases studies of chemical reactions were made with laboratory-like precision. Rate coefficients have been derived as functions of temperature for a number of important reactions. New information has been acquired on nearly every major process which occurs in the thermosphere, including the recombination rates of all major molecular ions, charge transfer reactions, ion atom interchange reactions, and reactions of neutral and ionized metastable atoms and molecules.
Bilateral medial medullary infarction due to bilateral vertebral artery dissection.
Fukuda, Masafumi; Aiba, Toyotaka; Takahashi, Sho
2004-03-01
We describe a 52-year-old woman who experienced transient motor weakness and numbness of the left extremities and presented 2 days later with severe hemiparesis and sensory impairment of the right extremities and right lingual palsy. Magnetic resonance imaging (MRI) revealed bilateral upper medial medullary infarction, primarily in the left ventral portion. The findings of both three-dimensional (3D) computed tomographic and conventional angiography suggested dissection of both intracranial vertebral arteries (VAs). Medial medullary infarction is generally caused by atherosclerosis within a VA or anterior spinal artery. This is the first report of bilateral medial medullary infarction due to dissection of both intracranial VAs.
A review of recent American military space operations
NASA Astrophysics Data System (ADS)
Day, Dwayne A.
1993-12-01
The United States (US) Department of Defense (DOD) has launched a large number of satellites into Earth orbit during the past five and a half years. These range from highly classified signals intelligence and imaging satellites to more mundane scientific and experimental microsats. This period saw a dramatic overhaul in operations due to the Challenger and other launch disasters. Many of these resources were used during the war in the Persian Gulf, which highlighted some of the limitations of current systems. A significant amount of new information has emerged in recent years due to the changing political situation, leading to this general overview of American military satellite programs during this period using unclassified and declassified sources as well as informed specculation. It is primarily a review of space operations and technical developments rather than the policy and doctrine that drives them.
Spatial aspects of tree mortality strongly differ between young and old-growth forests.
Larson, Andrew J; Lutz, James A; Donato, Daniel C; Freund, James A; Swanson, Mark E; HilleRisLambers, Janneke; Sprugel, Douglas G; Franklin, Jerry F
2015-11-01
Rates and spatial patterns of tree mortality are predicted to change during forest structural development. In young forests, mortality should be primarily density dependent due to competition for light, leading to an increasingly spatially uniform pattern of surviving trees. In contrast, mortality in old-growth forests should be primarily caused by contagious and spatially autocorrelated agents (e.g., insects, wind), causing spatial aggregation of surviving trees to increase through time. We tested these predictions by contrasting a three-decade record of tree mortality from replicated mapped permanent plots located in young (< 60-year-old) and old-growth (> 300-year-old) Abies amabilis forests. Trees in young forests died at a rate of 4.42% per year, whereas trees in old-growth forests died at 0.60% per year. Tree mortality in young forests was significantly aggregated, strongly density dependent, and caused live tree patterns to become more uniform through time. Mortality in old-growth forests was spatially aggregated, but was density independent and did not change the spatial pattern of surviving trees. These results extend current theory by demonstrating that density-dependent competitive mortality leading to increasingly uniform tree spacing in young forests ultimately transitions late in succession to a more diverse tree mortality regime that maintains spatial heterogeneity through time.
Surveillance of Suicidal Behavior, January through December 2014
2015-11-01
primarily for cannabis (49%), cocaine (36%), and amphetamines (17%). In the year before their death, 10% of the suicide cases from 2001 through...tests were primarily for cannabis (40%), cocaine (40%) and opiates (20%). ASAP Screening & Enrollment: In the year preceding the suicide, 10...had a positive drug test in the year before their suicide attempt. Positive tests were primarily for cannabis (47%) and cocaine (37%). 0 5 10
Attitudinal Changes Toward Homosexuality During the Past Two Decades (1994-2014) in Korea.
Youn, Gahyun
2018-01-01
This study was conducted to examine recent Korean perspectives on homosexuality by comparing attitudes toward mental illness, crime, friendship, and civil rights related to homosexual people in 1994, 1999, 2004, 2009, and 2014. The respondents were 3,299 Korean men and women between 18 and 59 years of age, and the data were collected across 5 years. The major findings were that there has been greater acceptance of homosexuality and civil rights for homosexuals during the past two decades, but the changes have been slow; Korean homosexuals remain subjects of social stigma and discrimination primarily due to increased Christian activism.
Pharmaceutical Cocrystals and Their Physicochemical Properties
2009-01-01
Over the last 20 years, the number of publications outlining the advances in design strategies, growing techniques, and characterization of cocrystals has continued to increase significantly within the crystal engineering field. However, only within the last decade have cocrystals found their place in pharmaceuticals, primarily due to their ability to alter physicochemical properties without compromising the structural integrity of the active pharmaceutical ingredient (API) and thus, possibly, the bioactivity. This review article will highlight and discuss the advances made over the last 10 years pertaining to physical and chemical property improvements through pharmaceutical cocrystalline materials and, hopefully, draw closer the fields of crystal engineering and pharmaceutical sciences. PMID:19503732
The Socialization of Men to the Nursing Profession: A Symbolic Interactionist Approach
ERIC Educational Resources Information Center
Wise, Rita E. Mullen
2009-01-01
The profession of nursing is composed, primarily of females. Hence, the profession becomes gendered due to the persons who primarily engage in the work and the characteristic that is primarily associated with the profession--caring. When men enter the profession, they are challenging the gendered image of the profession. Those individuals who…
Karmazyn, Morris; Gan, Xiaohong Tracey
2017-10-01
Heart failure is a major medical and economic burden throughout the world. Although various treatment options are available to treat heart failure, death rates in both men and women remain high. Potential adjunctive therapies may lie with use of herbal medications, many of which possess potent pharmacological properties. Among the most widely studied is ginseng, a member of the genus Panax that is grown in many parts of the world and that has been used as a medical treatment for a variety of conditions for thousands of years, particularly in Asian societies. There are a number of ginseng species, each possessing distinct pharmacological effects due primarily to differences in their bioactive components including saponin ginsenosides and polysaccharides. While experimental evidence for salutary effects of ginseng on heart failure is robust, clinical evidence is less so, primarily due to a paucity of large-scale well-controlled clinical trials. However, there is evidence from small trials that ginseng-containing Chinese medications such as Shenmai can offer benefit when administered as adjunctive therapy to heart failure patients. Substantial additional studies are required, particularly in the clinical arena, to provide evidence for a favourable effect of ginseng in heart failure patients.
Energy Information Administration quarterly coal report, October--December 1992
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1993-05-21
The United States produced just over 1 billion short tons of coal in 1992, 0.4 percent more than in 1991. Most of the 4-million-short-ton increase in coal production occurred west of the Mississippi River, where a record level of 408 million short tons of coal was produced. The amount of coal received by domestic consumers in 1992 totaled 887 million short tons. This was 7 million short tons more than in 1991, primarily due to increased coal demand from electric utilities. The average price of delivered coal to each sector declined by about 2 percent. Coal consumption in 1992 wasmore » 893 million short tons, only 1 percent higher than in 1991, due primarily to a 1-percent increase in consumption at electric utility plants. Consumer coal stocks at the end of 1992 were 163 million short tons, a decrease of 3 percent from the level at the end of 1991, and the lowest year-end level since 1989. US coal exports fell 6 percent from the 1991 level to 103 million short tons in 1992. Less coal was exported to markets in Europe, Asia, and South America, but coal exports to Canada increased 4 million short tons.« less
Direct healthcare costs of selected diseases primarily or partially transmitted by water.
Collier, S A; Stockman, L J; Hicks, L A; Garrison, L E; Zhou, F J; Beach, M J
2012-11-01
Despite US sanitation advancements, millions of waterborne disease cases occur annually, although the precise burden of disease is not well quantified. Estimating the direct healthcare cost of specific infections would be useful in prioritizing waterborne disease prevention activities. Hospitalization and outpatient visit costs per case and total US hospitalization costs for ten waterborne diseases were calculated using large healthcare claims and hospital discharge databases. The five primarily waterborne diseases in this analysis (giardiasis, cryptosporidiosis, Legionnaires' disease, otitis externa, and non-tuberculous mycobacterial infection) were responsible for over 40 000 hospitalizations at a cost of $970 million per year, including at least $430 million in hospitalization costs for Medicaid and Medicare patients. An additional 50 000 hospitalizations for campylobacteriosis, salmonellosis, shigellosis, haemolytic uraemic syndrome, and toxoplasmosis cost $860 million annually ($390 million in payments for Medicaid and Medicare patients), a portion of which can be assumed to be due to waterborne transmission.
Direct healthcare costs of selected diseases primarily or partially transmitted by water
COLLIER, S. A.; STOCKMAN, L. J.; HICKS, L. A.; GARRISON, L. E.; ZHOU, F. J.; BEACH, M. J.
2015-01-01
SUMMARY Despite US sanitation advancements, millions of waterborne disease cases occur annually, although the precise burden of disease is not well quantified. Estimating the direct healthcare cost of specific infections would be useful in prioritizing waterborne disease prevention activities. Hospitalization and outpatient visit costs per case and total US hospitalization costs for ten waterborne diseases were calculated using large healthcare claims and hospital discharge databases. The five primarily waterborne diseases in this analysis (giardiasis, cryptosporidiosis, Legionnaires’ disease, otitis externa, and non-tuberculous mycobacterial infection) were responsible for over 40 000 hospitalizations at a cost of $970 million per year, including at least $430 million in hospitalization costs for Medicaid and Medicare patients. An additional 50 000 hospitalizations for campylobacteriosis, salmonellosis, shigellosis, haemolytic uraemic syndrome, and toxoplasmosis cost $860 million annually ($390 million in payments for Medicaid and Medicare patients), a portion of which can be assumed to be due to waterborne transmission. PMID:22233584
Europa Explorer - An Exceptional Mission Using Existing Technology
NASA Technical Reports Server (NTRS)
Clark, Karla B.
2007-01-01
A mission to Europa has been identified as a high priority by the science community for several years. The difficulty of an orbital mission, primarily due to the propulsive requirements and Jupiter's trapped radiation, led to many studies which investigated various approaches to meeting the science goals. The Europa Orbiter Mission studied in the late 1990's only met the most fundamental science objectives. The science objectives have evolved with the discoveries from the Galileo mission. JPL studied one concept, Europa Explorer, for a Europa orbiting mission which could meet a much expanded set of science objectives. A study science group was formed to verify that the science objectives and goals were being adequately met by the resulting mission design concept. The Europa Explorer design emerged primarily from two key self-imposed constraints: 1) meet the full set of identified nonlander science objectives and 2) use only existing technology.
Relative Sea Level, Tidal Range, and Extreme Water Levels in Boston Harbor from 1825 to 2016
NASA Astrophysics Data System (ADS)
Talke, S. A.; Kemp, A.; Woodruff, J. D.
2017-12-01
Long time series of water-level measurements made by tide gauges provide a rich and valuable observational history of relative sea-level change, the frequency and height of extreme water levels and evolving tidal regimes. However, relatively few locations have available tide-gauge records longer than 100 years and most of these places are in northern Europe. This spatio-temporal distribution hinders efforts to understand global-, regional- and local-scale trends. Using newly-discovered archival measurements, we constructed a 200 year, instrumental record of water levels, tides, and storm surges in Boston Harbor. We detail the recovery, datum reconstruction, digitization, quality assurance, and analysis of this extended observational record. Local, decadally-averaged relative sea-level rose by 0.28 ± 0.05 m since the 1820s, with an acceleration of 0.023 ±0.009 mm/yr2. Approximately 0.13 ± 0.02 m of the observed RSL rise occurred due to ongoing glacial isostatic adjustment, and the remainder occurred due to changes in ocean mass and volume associated with the onset of modern mean sea-level rise. Change-point analysis of the new relative sea level record confirms that anthropogenic rise began in 1924-1932, which is in agreement with global mean sea level estimates from the global tide gauge network. Tide range decreased by 5.5% between 1830 and 1910, likely due in large part to anthropogenic development. Storm tides in Boston Harbor are produced primarily by extratropical storms during the November-April time frame. The three largest storm tides occurred in 1851, 1909, and 1978. Because 90% of the top 20 storm tides since 1825 occurred during a spring tide, the secular change in tide range contributes to a slight reduction in storm tide magnitudes. However, non-stationarity in storm hazard was historically driven primarily by local relative sea-level rise; a modest 0.2 m increase in relative sea level reduces the 100 year high water mark to a once-in-10 year event.
Vertical motions in the Uranian atmosphere - An analysis of radio observations
NASA Technical Reports Server (NTRS)
Hofstadter, Mark D.; Berge, Glenn L.; Muhleman, Duane O.
1990-01-01
The present, 6-cm radio map of Uranus indicates latitudinal features which may be due to vertical motions of the atmosphere. It appears in light of Voyager IR measurements as well as previously obtained radio data that these large-scale vertical motions, which have not undergone significant changes over the course of 8 years, extend from the 0.1- to the 45-bar levels; this span corresponds to a height of the order of 250 km. The latitudinal structures are believed to be primarily caused by horizontal variations of absorber abundances.
Tuncer, Samuray; Sencer, Serra; Kebudi, Rejin; Tanyıldız, Burak; Cebeci, Zafer; Aydın, Kubilay
2016-11-01
To report our 4-year experience in Turkey, with advanced intra-ocular retinoblastoma managed primarily with intra-arterial chemotherapy (IAC). From October 2011 to September 2015, 26 group D eyes of 24 treatment-naïve retinoblastoma patients managed primarily with IAC were evaluated in this prospective study. Of 76 procedures, ophthalmic artery cannulation failed in two patients with unilateral involvement. In the remaining 22 patients (24 eyes), the mean age at diagnosis was 18 months (range, 6-55 months). Each eye received a mean of 3 IAC sessions/eye (range, 2-5 sessions). After a median follow-up of 29 months (range, 6-55 months), complete regression of the main tumour was achieved in 23 of 24 eyes. One eye with partial regression required enucleation due to ciliary body involvement by the tumour. Overall, 16 eyes (66.6%) were salvaged with primary IAC with or without additional local treatments, and eight (33.3%) required enucleation. The main IAC-related periocular complications included transient eyelid oedema (n = 13), ptosis (n = 6) and forehead hyperpigmentation (n = 3), each resolving in 2 weeks to 4 months. Intra-ocular complications included chorioretinal atrophy (n = 9), newly noted retinal detachment (n = 5) and vitreous haemorrhage (n = 1). Kaplan-Meier eye estimates of enucleation-free survival rates were 83.3% (95% CI, 68.4-98.1%), 69.1% (95% CI, 49.8-88.3%) and 62.9 (95% CI, 41.9-83.8%) at 6 months, 1 and 2 years, respectively, and stable thereafter. Our first 4-year experience in Turkey showed that enucleation or external-beam radiotherapy could be avoided in two-thirds of eyes with advanced intra-ocular retinoblastoma managed primarily with IAC. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
NASA Technical Reports Server (NTRS)
Onstott, R. G.; Kim, Y. S.; Moore, R. K.
1984-01-01
A series of measurements of the active microwave properties of sea ice under fall growing conditions was conducted. Ice in the inland waters of Mould Bay, Crozier Channel, and intrepid inlet and ice in the Arctic Ocean near Hardinge Bay was investigated. Active microwave data were acquired using a helicopter borne scatterometer. Results show that multiyear ice frozen in grey or first year ice is easily detected under cold fall conditions. Multiyear ice returns were dynamic due to response to two of its scene constituents. Floe boundaries between thick and thin ice are well defined. Multiyear pressure ridge returns are similar in level to background ice returns. Backscatter from homogeneous first year ice is seen to be primarily due to surface scattering. Operation at 9.6 GHz is more sensitive to the detailed changes in scene roughness, while operation at 5.6 GHz seems to track roughness changes less ably.
Winter foraging guild structure and habitat associations in suburban bird communities
Richard M. DeGraaf
1991-01-01
Winter bird communities were compared in three suburbs over 5 years: MT, a 70-year-old area of large houses and planted mature trees, primarily oaks (Quercus) and elms (Ulmus); YT, a 15-year-old area also built upon former open agricultural land with young planted trees, primarily maples (Acer); OP, a 15-...
Mirzaei, Lida; Kaal, Suzanne E J; Schreuder, Hendrik W B; Bartels, Ronald H M A
2015-11-01
The vertebral column is an infrequent site of primary involvement in Ewing sarcoma. Yet when Ewing sarcoma is found in the spine, the urge for decompression is high because of the often symptomatic compression of neural structures. It is unclear in alleviating a neurological deficit whether chemotherapy is preferred over decompressive laminectomy. To underline, in this case series, the efficiency of initial chemotherapy before upfront surgery in the setting of high-grade spinal cord or cauda equina compression of primary Ewing sarcoma. Fifteen patients with Ewing sarcoma primarily located in the spine were treated at our institution between 1983 and 2015. Localization, neurological deficit expressed as Frankel grade, and outcome expressed as Rankin scale before and after initial chemotherapy, the recurrence rate, and overall survival were evaluated. The multidisciplinary approach of 1 case will be discussed in detail. Nine patients (60%) were female. The age at presentation was 15.0 ± 5.5 years (range: 0.9-22.8 years). Ten patients (67%) were initially treated with chemotherapy, and 1 patient (7%) was treated primarily with radiotherapy followed by chemotherapy. The remaining 4 patients (27%) were initially treated with decompressive surgery. All patients treated primarily nonsurgically improved neurologically at follow-up, showing the importance of chemotherapy as an effective initial treatment option. Adequate and quick decompression of neural structures with similar results can be achieved by chemotherapy and radiotherapy, avoiding the local spill of malignant cells.
Global estimation of CO emissions using three sets of satellite data for burned area
NASA Astrophysics Data System (ADS)
Jain, Atul K.
Using three sets of satellite data for burned areas together with the tree cover imagery and a biogeochemical component of the Integrated Science Assessment Model (ISAM) the global emissions of CO and associated uncertainties are estimated for the year 2000. The available fuel load (AFL) is calculated using the ISAM biogeochemical model, which accounts for the aboveground and surface fuel removed by land clearing for croplands and pasturelands, as well as the influence on fuel load of various ecosystem processes (such as stomatal conductance, evapotranspiration, plant photosynthesis and respiration, litter production, and soil organic carbon decomposition) and important feedback mechanisms (such as climate and fertilization feedback mechanism). The ISAM estimated global total AFL in the year 2000 was about 687 Pg AFL. All forest ecosystems account for about 90% of the global total AFL. The estimated global CO emissions based on three global burned area satellite data sets (GLOBSCAR, GBA, and Global Fire Emissions Database version 2 (GFEDv2)) for the year 2000 ranges between 320 and 390 Tg CO. Emissions from open fires are highest in tropical Africa, primarily due to forest cutting and burning. The estimated overall uncertainty in global CO emission is about ±65%, with the highest uncertainty occurring in North Africa and Middle East region (±99%). The results of this study suggest that the uncertainties in the calculated emissions stem primarily from the area burned data.
Rangeland -- Plant responses to elevated CO sub 2
DOE Office of Scientific and Technical Information (OSTI.GOV)
Owensby, C.E.; Coyne, P.I.; Ham, J.M.
1992-01-01
Several broad conclusions which can be drawn from the work that was accomplished during the first 3-year phase of the study is described. In prairie ecosystems dominated by C{sub 4} grasses, it is likely that elevated atmospheric CO{sub 2} will increase ecosystem level productivity, with a greater increase in belowground productivity. The increased productivity will primarily result from increased water use efficiency due to the anti-transpirant action of CO{sub 2}. Fumigation chambers are directly confounded with elevated CO{sub 2} effects, in that both reduce evapotranspiration. The reduced evapotranspiration of the fumigation chamber is primarily through reduced wind speeds and reducedmore » radiation. In very dry years, fumigation chamber effects are negligible, but in years with normal precipitation, chamber effects and elevated CO{sub 2} effects are essentially equal with respect to reduced evapotranspiration effects. Increased production under elevated CO{sub 2} results in reduced nitrogen concentration in the herbage and increased fiber concentrations. Consequently, digestibility of the herbage is reduced, and microbial degradation of surface litter and soil organic matter is slowed. On the negative side, ruminant productivity will likely be reduced substantially, but increased carbon storage in the soil may buffer against future rise in atmospheric CO{sub 2}. Tallgrass prairie will not likely change greatly in botanical composition, since the C{sub 4} dominants responded to elevated CO{sub 2} more than the C{sub 3} subdominants.« less
Water Resources of Beauregard Parish
Prakken, Lawrence B.; Griffith, Jason M.; Fendick, Robert B.
2012-01-01
In 2005, about 30.6 million gallons per day (Mgal/d) of water was withdrawn in Beauregard Parish, Louisiana, including about 30.4 Mgal/d from groundwater sources and 0.1 Mgal/d from surface water sources. Industrial use, primarily for wood products, accounted for about 72 percent (22.0 Mgal/d) of the total water withdrawn. Other categories of use included public supply, rural domestic, livestock, rice irrigation, general irrigation, and aquaculture. Water-use data collected at 5-year intervals from 1960 to 2005 indicate water withdrawals in the parish peaked at about 43.5 Mgal/d in 1985. The large increase in groundwater usage from 1970 to 1975 was primarily due to industrial withdrawals, which increased from 3.64 Mgl/d in 1970 to 29.0 Mgal/d in 1975. This fact sheet summarizes information on the water resources of Beauregard Parish, La. Information on groundwater and surface-water availability, quality, development, use, and trends is based on previously published reports listed in the Selected References section.
Early and middle adolescents' disclosure to parents about activities in different domains.
Smetana, Judith G; Villalobos, Myriam; Tasopoulos-Chan, Marina; Gettman, Denise C; Campione-Barr, Nicole
2009-06-01
Disclosure, disclosure strategies, and justifications for nondisclosure for prudential, peer, multifaceted, and personal acts were assessed using a sorting task with 118 lower-middle class early and middle adolescents (Ms=12.77 and 15.68 years). Adolescents were less involved in prudential than other behaviors, although prudential behavior was greater among middle than early adolescents; adolescents disclosed more about prudential and personal than multifaceted and peer behaviors. Nondisclosure was primarily due to concerns about parental disapproval (for prudential acts), claims that acts were personal or not harmful (for personal acts), and their mixture (for peer and multifaceted acts). When concerned about parental disapproval, older adolescents fully disclosed less (and lied somewhat more) than younger adolescents, whereas adolescents primarily avoided discussing the issue when they viewed acts as personal. Full disclosure was associated with better relationships with parents and less depressed mood; lying was associated with more parental behavioral control over personal issues and poorer relationships with fathers.
Singh, Ashutosh; Singh, Pradeep Kumar; Kumar, Anil; Chander, Jagdish; Khanna, Geetika; Roy, Pradip; Meis, Jacques F; Chowdhary, Anuradha
2017-04-01
Melanized or black fungi are a heterogeneous group of fungi causing cutaneous to systemic diseases with high mortality. These fungi are rarely reported as agents of human infections, primarily due to difficulties in their classical identification. In this study, we examined, using molecular methods and matrix-assisted laser desorption ioniazation-time of flight mass spectrometry (MALDI-TOF MS), the diversity of melanized fungi (MF) isolated from patients in 19 medical centers in India. Overall, during a 4-year period, 718 (5.3%) clinical specimens yielded MF. Of these, 72 (10%) isolates had clinical significance and were identified primarily by sequencing the internal transcribed spacer and large subunit (LSU) regions. MF represented 21 genera comprising 29 species, the majority of them belonging to the orders Pleosporales (50%) and Chaetothyriales (22%). Among the 29 fungal species identified in this study, only 6 (20%) species were identified by the MALDI-TOF MS due to the limited commercial database of Bruker Daltonics for MF. However, a 100% identification rate of 20 additional species identified in this study was obtained by constructing an in-house database using 24- to 96-h-old liquid cultures. Further, the CLSI broth microdilution method revealed low MICs for posaconazole (≤1 μg/ml) and voriconazole (≤2 μg/ml) in 96% and 95% of isolates, respectively. Skin/subcutaneous and sino-nasal and pulmonary phaeohyphomycosis due to MF were diagnosed in 21.4% ( n = 15) and 28.5% ( n = 20) of cases. Also, 10% of patients had central nervous system involvement ( n = 7), and 3 cases of fungal osteomyelitis due to Cladophialophora bantiana and Corynespora spp. were observed. Copyright © 2017 American Society for Microbiology.
NASA Astrophysics Data System (ADS)
Heyerdahl, Håkon; Høydal, Øyvind
2016-04-01
The Gudbrandsdalen valley in Eastern Norway lies in a region where annual precipitation is generally low (down to 300 mm/year). The landslide activity has consequently historically been low, although the lower part of the valley sides generally is draped with thick layers of Quaternary deposits, primarily of glacial or glaciofluvial origin. The perception of natural hazards in the valley was previously primarily connected to flooding in the main river in the valley bottom during early summer, due to large discharges resulting from snowmelt in the mountainous regions west and east of the valley. However, several high-intensity events have changed the image of the region. Starting with a localized, but intense, landslide event in the Northern part of the valley in year 2008, two larger events covering almost the entire valley occurred in the years 2011 and 2013. A high number of landslides was triggered in all these events, including many flash floods and debris flows/debris slides in small and steep tributary rivers along the valley slopes. Landslide triggering covers different release mechanisms: In 2008, landslides were triggered without precipitation in not-frozen soil deposits without snow cover in the lower part of the valley. Groundwater flow through the permeable bedrock ("Otta schist") resulting from snow-melt in the elevated mountainous areas caused landslide triggering due to positive pore-water pressures forming at the bedrock surface below soil deposits, or at depressions in the terrain. Subsequent rainfall resulted in even more landslides being released. In later events (years 2011 and 2013) many landslides were caused by surface water taking new paths downslope, often due to man-made changes in existing waterways (typically poorly planned drainage solutions or new roads). Relatively small discharges in slopes with unconsolidated and easily erodible glacial deposits (typically lateral moraine) in many cases lead to small initial slides that down-slope developed into large erosional debris slides/floods of considerable size. Also along existing tributary rivers, the intense rainfall events resulted in flash-floods with heavy erosion and entrainment of deposits from the riverbed, including massive transport of trees. Also on open slopes a number of landslides were observed, assumedly triggered primarily by direct infiltration of rainfall, and possibly assisted by groundwater flow in underlying bedrock. Considerable damage to infrastructure and also dwellings has resulted from the events. A new approach has proved necessary to capture the risk elements connect to landslide and flood for this valley region when it comes to planning purposes. Among others, there is a need to consider the potential damage resulting from under-dimensioned culverts leading to complete failure of railroad or road embankments). Work is underway in order to improve the understanding of release mechanisms for typical landslides in the valley, which also will be highly relevant for other areas in Norway were similar natural hazards are encountered, and where climatic change may change the regional landslide activity.
Interface fluid syndrome in human eye bank corneas after LASIK: causes and pathogenesis.
Dawson, Daniel G; Schmack, Ingo; Holley, Glenn P; Waring, George O; Grossniklaus, Hans E; Edelhauser, Henry F
2007-10-01
To evaluate the effects of corneal edema on human donor corneas that had previous LASIK using a laboratory model with histologic and ultrastructural correlations. Experimental study. Thirty human eye bank corneas from 15 donors (mean age +/- standard deviation, 49.9+/-8.9 years) who had had previous LASIK surgery (2-8 years before death). The corneas were mounted in an artificial anterior chamber and the corneal endothelium was perfused for up to 5.0 hours with 0.9% saline solution (endothelial cell damage group) or BSS Plus at a pressure of 15 mmHg (control group), or BSS Plus at a pressure of 55 mmHg (high-pressure group). The corneas were evaluated by confocal and specular microscopy before, during, and at the end of the experimental period. Subsequently, the specimens were evaluated by light and electron microscopy. Corneal thickness, reflectivity, histology, and ultrastructure. Endothelial cell damage resulted in an increased (141.5+/-38.8 microm) total corneal thickness relative to controls (52.3+/-33.7 microm), whereas high pressure resulted in a decreased thickness (24.8+/-14.1 microm) relative to controls. This ultimately was due to swelling of the LASIK interface in both groups and swelling of the residual stromal bed (RSB) in the endothelial cell damage group or compression of the RSB and, possibly, the flap in the high-pressure group. A significant increase in corneal reflectivity at the LASIK interface occurred in both groups, primarily due to varying degrees of fluid accumulation and associated hydropic keratocyte degeneration, as well as increased corneal reflectivity in the RSB only in the endothelial cell damage group. After LASIK surgery, edematous corneas preferentially hydrate and swell in the paracentral and central interface wound, commonly resulting in a hazy corneal appearance primarily due to keratocyte hydropic degeneration. More severe corneal edema is characterized by the formation of an optically empty space corresponding to an interface fluid pocket. The spectrum of interface fluid syndrome can be described in 3 stages.
Papilloedema due to Chiari I malformation
Zhang, Jason Chao; Bakir, Belal; Lee, Andrew; Yalamanchili, Sushma S
2011-01-01
The Chiari I malformation is a congenital abnormality characterised by downward displacement of the cerebellar tonsils through the foramen magnum into the cervical spine. It presents clinically most often in young adult women. Known ocular manifestations linked to Chiari I consist primarily of oculomotor paresis with cranial nerve VI palsy and convergence/divergence abnormalities. Papilloedema is a rare manifestation of Chiari I with a clinical presentation often similar to that of idiopathic intracranial hypertension. To highlight this unusual complication, the authors report a 64-year-old female who developed papilloedema as the only presenting neurological symptom resulting from a Chiari I malformation. PMID:22675036
[Hepatocellular tumours in noncirrhotic liver tissue].
Goltz, D; Fischer, H-P
2015-11-01
In recent years, the spectrum of tissue-based diagnostics of hepatocellular tumours has changed due to novel molecular pathological findings. Innovative radiographics filter out small lesions and ambiguous tumours for bioptical sampling. The spectrum of these tumours includes hepatocellular carcinoma, hepatocellular adenomas, focal nodular hyperplasia and macroregenerative nodules. Primarily, morphological analysis should identify the dignity of a lesion. After exclusion of HCC and reactive liver cell nodules, hepatocellular adenomas should be further subclassified based on immunohistochemical/molecular pathological criteria according to the WHO classification of liver tumours. This procedure provides significant additional information regarding the prognosis and therapeutic implications of hepatocellular adenomas.
Luengo-Fernandez, Ramon; Silver, Louise E; Gutnikov, Sergei A; Gray, Alastair M; Rothwell, Peter M
2013-01-01
High hospitalization rates, prolonged length of stay, and increased risks of subsequent events mean a steep increase in health care usage after stroke. No study, however, has examined to what extent increased costs after transient ischemic attack (TIA) or stroke are due to hospitalizations for the initial event, recurrent events, and/or nonvascular hospitalizations, and how costs compare with the year prior to the event. We studied patients in a population-based cohort study (Oxford Vascular Study) in the United Kingdom from 2003 to 2007. Hospitalization and cost details were obtained from patients' individualized Hospital Episode Statistics records. A total of 295 incident TIA and 439 incident stroke patients were included. For patients with stroke, average costs increased from £1437 in the year pre-event to £6629 in the year post-event (P<0.0001). Sixty-four percent (£4224) of poststroke costs were due to hospitalizations linked to the index stroke, more than 30% of which were given nonvascular primary diagnoses on Hospital Episode Statistics, and £653 (10%) were due to hospitalizations linked to subsequent vascular events. For patients with TIA, costs increased from £876 1 year before the event to £2410 in the year post-event (P<0.0001). Patients with TIA incurred nonsignificantly higher costs due to hospitalizations linked to subsequent vascular events (£774) than for hospitalizations linked to the index TIA (£720). Hospital costs increased after TIA or stroke, primarily because of increased initial cerebrovascular hospitalizations. The finding that costs due to nonvascular diagnoses also increased after TIA or stroke appears, in part, to be explained by the miscoding of TIA/stroke-related hospitalizations in electronic information systems. Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.
Pesticide-induced quadriplegia in a 55-year-old woman.
Beavers, Charles T; Parker, Joseph J; Flinchum, Dane A; Weakley-Jones, Barbara A; Jortani, Saeed A
2014-12-01
Acephate is a commercial organophosphate pesticide formerly used in households and now used primarily for agriculture. Poisoning symptoms include salivation, lacrimation, urination, defecation, gastrointestinal illness, and emesis. In addition to these classic symptoms, neurodegeneration can result from increased and continued exposure of organophosphates. This 55-year-old woman presented with organophosphate-induced delayed neuropathy in the form of quadriplegia due to the commonly used pesticide acephate. She was exposed to this pesticide through multiple sprayings in her work office with underrecognized poisoning symptoms. She presented to her primary care physician with neuropathic pain and paralysis in her arm following the sprayings and eventual complete paralysis. The patient lived for 2 years following her toxic exposure and quadriplegia. A complete autopsy after her death confirmed a transverse myelitis in her spinal cord. We conclude that in susceptible individuals, acephate in excessive amounts can produce severe delayed neurotoxicity as demonstrated in animal studies.
The Cost of Uncertain Life Span*
Edwards, Ryan D.
2012-01-01
A considerable amount of uncertainty surrounds the length of human life. The standard deviation in adult life span is about 15 years in the U.S., and theory and evidence suggest it is costly. I calibrate a utility-theoretic model of preferences over length of life and show that one fewer year in standard deviation is worth about half a mean life year. Differences in the standard deviation exacerbate cross-sectional differences in life expectancy between the U.S. and other industrialized countries, between rich and poor countries, and among poor countries. Accounting for the cost of life-span variance also appears to amplify recently discovered patterns of convergence in world average human well-being. This is partly for methodological reasons and partly because unconditional variance in human length of life, primarily the component due to infant mortality, has exhibited even more convergence than life expectancy. PMID:22368324
Fourier Phase Domain Steganography: Phase Bin Encoding Via Interpolation
NASA Astrophysics Data System (ADS)
Rivas, Edward
2007-04-01
In recent years there has been an increased interest in audio steganography and watermarking. This is due primarily to two reasons. First, an acute need to improve our national security capabilities in light of terrorist and criminal activity has driven new ideas and experimentation. Secondly, the explosive proliferation of digital media has forced the music industry to rethink how they will protect their intellectual property. Various techniques have been implemented but the phase domain remains a fertile ground for improvement due to the relative robustness to many types of distortion and immunity to the Human Auditory System. A new method for embedding data in the phase domain of the Discrete Fourier Transform of an audio signal is proposed. Focus is given to robustness and low perceptibility, while maintaining a relatively high capacity rate of up to 172 bits/s.
NASA Astrophysics Data System (ADS)
Zhang, Zhiqiang; Chen, Liang; Wang, Weiping; Li, Tuanjie; Zu, Tingting
2017-04-01
We analyzed heavy metal concentrations in a number of surface sediments and cores from the Qiongzhou Strait and surrounding marine areas. The areas of high concentrations are primarily outside the eastern mouth of the Qiongzhou Strait and on the west side of the Leizhou Peninsula, whereas the areas of low concentrations are located primarily in the eastern Qiongzhou Strait. The maximum Cd, Pb and Zn concentrations in the samples collected in our study do not exceed the official standards for marine sediments, whereas the concentrations of Cr and Cu slightly exceed the standards. Correlations exist between the concentrations of Cu, Pb, Zn, Cr and Cd, and the concentrations of these metals are positively correlated with the mean particle size (φ value), indicating that the finer sediments have adsorbed greater amounts of heavy metal elements than the coarser sediments. An evaluation of the potential environmental risks demonstrates that certain indices of heavy metal pollution and environmental risks are relatively low and may be assigned low risk levels, thereby indicating that, in terms of heavy metals, the marine sedimentary environment in this region is only mildly impacted. Our analysis of the contaminant origins shows that the heavy metals in this region primarily originate in the Pearl River Estuary and that a small amount of them is derived from local runoff. The elevated heavy metal concentrations from the upper sections of the cores started 130 years ago, which indicats that heavy metals in the surface sediments are primarily due to human activities associated with industrialization.
Impact on short-lived climate forcers increases projected warming due to deforestation.
Scott, C E; Monks, S A; Spracklen, D V; Arnold, S R; Forster, P M; Rap, A; Äijälä, M; Artaxo, P; Carslaw, K S; Chipperfield, M P; Ehn, M; Gilardoni, S; Heikkinen, L; Kulmala, M; Petäjä, T; Reddington, C L S; Rizzo, L V; Swietlicki, E; Vignati, E; Wilson, C
2018-01-11
The climate impact of deforestation depends on the relative strength of several biogeochemical and biogeophysical effects. In addition to affecting the exchange of carbon dioxide (CO 2 ) and moisture with the atmosphere and surface albedo, vegetation emits biogenic volatile organic compounds (BVOCs) that alter the formation of short-lived climate forcers (SLCFs), which include aerosol, ozone and methane. Here we show that a scenario of complete global deforestation results in a net positive radiative forcing (RF; 0.12 W m -2 ) from SLCFs, with the negative RF from decreases in ozone and methane concentrations partially offsetting the positive aerosol RF. Combining RFs due to CO 2 , surface albedo and SLCFs suggests that global deforestation could cause 0.8 K warming after 100 years, with SLCFs contributing 8% of the effect. However, deforestation as projected by the RCP8.5 scenario leads to zero net RF from SLCF, primarily due to nonlinearities in the aerosol indirect effect.
NASA Astrophysics Data System (ADS)
Emerson, Hilary P.; Hart, Ashley E.; Baldwin, Jonathon A.; Waterhouse, Tyler C.; Kitchens, Christopher L.; Mefford, O. Thompson; Powell, Brian A.
2014-02-01
In recent years, there has been increasing concern regarding the fate and transport of engineered nanoparticles (NPs) in environmental systems and the potential impacts on human and environmental health due to the exponential increase in commercial and industrial use worldwide. To date, there have been relatively few field-scale studies or laboratory-based studies on environmentally relevant soils examining the chemical/physical behavior of the NPs following release into natural systems. The objective of this research is to demonstrate the behavior and transformations of iron oxide and silver NPs with different capping ligands within the unsaturated zone. Here, we show that NP transport within the vadose zone is minimal primarily due to heteroaggregation with soil surface coatings with results that >99 % of the NPs remained within 5 cm of the original source after 1 year in intermediate-scale field lysimeters. These results suggest that transport may be overestimated when compared to previous laboratory-scale studies on pristine soils and pure minerals and that future work must incorporate more environmentally relevant parameters.
Rangeland -- Plant responses to elevated CO{sub 2}. Progress report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Owensby, C.E.; Coyne, P.I.; Ham, J.M.
1992-10-01
Several broad conclusions which can be drawn from the work that was accomplished during the first 3-year phase of the study is described. In prairie ecosystems dominated by C{sub 4} grasses, it is likely that elevated atmospheric CO{sub 2} will increase ecosystem level productivity, with a greater increase in belowground productivity. The increased productivity will primarily result from increased water use efficiency due to the anti-transpirant action of CO{sub 2}. Fumigation chambers are directly confounded with elevated CO{sub 2} effects, in that both reduce evapotranspiration. The reduced evapotranspiration of the fumigation chamber is primarily through reduced wind speeds and reducedmore » radiation. In very dry years, fumigation chamber effects are negligible, but in years with normal precipitation, chamber effects and elevated CO{sub 2} effects are essentially equal with respect to reduced evapotranspiration effects. Increased production under elevated CO{sub 2} results in reduced nitrogen concentration in the herbage and increased fiber concentrations. Consequently, digestibility of the herbage is reduced, and microbial degradation of surface litter and soil organic matter is slowed. On the negative side, ruminant productivity will likely be reduced substantially, but increased carbon storage in the soil may buffer against future rise in atmospheric CO{sub 2}. Tallgrass prairie will not likely change greatly in botanical composition, since the C{sub 4} dominants responded to elevated CO{sub 2} more than the C{sub 3} subdominants.« less
Precursor B-cell lymphoblastic lymphoma of oral cavity: A case report with its diagnostic workup
Talreja, Komal Ladharam; Barpande, Suresh Ramchandra; Bhavthankar, Jyoti Dilip; Mandale, Mandakini S
2016-01-01
Lymphoblastic lymphoma (LBL), seen primarily in children or young adults, is a malignant neoplasia that originates from B or T lymphocyte precursors and rarely occurs in the oral cavity. In this localization, neither the clinical features nor the radiologic appearances are pathognomic and can pose significant diagnostic problems. Histopathologically, it presents as a round blue cell tumor. An early and accurate diagnosis of this entity is very important due to its high cure rate. We report a case of B-cell LBL involving oral cavity in a 10-year-old child. The purpose of this report is to explore the diagnostic workup. PMID:27194876
[Cardiac myopathy due to overt hypothyroidism].
Harbeck, B; Berndt, M J; Lehnert, H
2014-03-01
A 51-year-old man presented with progressive tiredness, proximal muscle weakness, hair loss and weight gain for months. The patient showed mild pretibial myxedema and dry skin. Laboratory findings revealed strongly elevated cardiac enzymes as well as marked hypothyroidism. The electrocardiogram, echocardiography, abdominal sonography and chest X-ray were unremarkable. Thyroid ultrasound demonstrated features of Hashimoto thyroiditis. The findings supported the diagnosis of an overt hypothyroidism with myxedema and rhabdomyolysis. After starting levothyroxine and volume substitution laboratory parameters and clinical condition slowly normalized. Severe overt hypothyroidism may rarely present primarily as myopathy with myositis and cardiac involvement. © Georg Thieme Verlag KG Stuttgart · New York.
Chakrabortty, Shushovan; Gupta, Deepak; Rustom, David; Berry, Hussein; Rai, Ajit
2014-01-01
The current retrospective study was completed with the aim to identify demographic characteristics and clinical predictors (if any) of the patients discharged from our pain clinic due to breach in narcotic use contract (BNUC). Retrospective patient charts' review and data audit. University hospital-affiliated pain clinic in the United States. All patient charts in our pain clinic for a 2-year period (2011-2012). The patients with BNUC were delineated from the patients who had not been discharged from our pain clinic. Pain characteristics, pain management, and substance abuse status were compared in each patient with BNUC between the time of admission and the time of discharge. The patients with BNUC discharges showed significant variability for the discharging factors among the pain physicians within a single pain clinic model with this variability being dependent on their years of experience and their proactive interventional pain management. The patients with BNUC in our pain clinic setting were primarily middle-aged, obese, unmarried males with nondocumented stable occupational history who were receiving only noninterventional pain management. Substance abuse, doctor shopping, and potential diversion were the top three documented reasons for BNUC discharges. In 2011-2012, our pain clinic discharged 1-in-16 patients due to breach in narcotic use contract.
Declines in Sexual Frequency among American Adults, 1989-2014.
Twenge, Jean M; Sherman, Ryne A; Wells, Brooke E
2017-11-01
American adults had sex about nine fewer times per year in the early 2010s compared to the late 1990s in data from the nationally representative General Social Survey, N = 26,620, 1989-2014. This was partially due to the higher percentage of unpartnered individuals, who have sex less frequently on average. Sexual frequency declined among the partnered (married or living together) but stayed steady among the unpartnered, reducing the marital/partnered advantage for sexual frequency. Declines in sexual frequency were similar across gender, race, region, educational level, and work status and were largest among those in their 50s, those with school-age children, and those who did not watch pornography. In analyses separating the effects of age, time period, and cohort, the decline was primarily due to birth cohort (year of birth, also known as generation). With age and time period controlled, those born in the 1930s (Silent generation) had sex the most often, whereas those born in the 1990s (Millennials and iGen) had sex the least often. The decline was not linked to longer working hours or increased pornography use. Age had a strong effect on sexual frequency: Americans in their 20s had sex an average of about 80 times per year, compared to about 20 times per year for those in their 60s. The results suggest that Americans are having sex less frequently due to two primary factors: An increasing number of individuals without a steady or marital partner and a decline in sexual frequency among those with partners.
Assessment of public vs private MSW management: a case study.
Massoud, M A; El-Fadel, M; Abdel Malak, A
2003-09-01
Public-private partnerships in urban environmental services have witnessed increased interest in recent years primarily to reform the weak performance of the public sector, reduce cost, improve efficiency, and ensure environmental protection. In this context, successful public-private partnerships require a thorough analysis of opportunities, a deliberate attention to process details, and a continuous examination of services to determine whether they are more effectively performed by the private sector. A comparative assessment of municipal solid waste collection services in the two largest cities in Lebanon where until recently municipal solid waste collection is private in one and public in the other is conducted. While quality of municipal solid waste collection improved, due to private sector participation, the corresponding cost did not, due to monopoly and an inadequate organizational plan defining a proper division of responsibilities between the private and the public sector.
Slegers, C A D; Keuter, M; Günther, S; Schmidt-Chanasit, J; van der Ven, A J; de Mast, Q
2014-07-01
The 2014 FIFA World Cup and the 2016 Olympic Games will attract large groups of visitors to Brazil. These visitors will be at risk for different arboviral infections, some of which not well known outside endemic areas. We report a case of a 52-year-old Dutch woman who presented with persistent arthralgia due to a Mayaro virus (MAYV) infection which she contracted in the Amazon basin in Brazil. MAYV is a mosquito-borne alphavirus which primarily circulates in humid tropical forests of South America. Infections are rarely reported in travelers and are characterized by an acute febrile illness which is often followed by a prolonged and sometimes incapacitating polyarthralgia. Both travelers and physicians should be aware of the risk of these arboviral infections and the importance of mosquito bite prevention should be stressed. Copyright © 2014 Elsevier B.V. All rights reserved.
Rapid Resolution of Grief with IV Infusion of Ketamine: A Unique Phenomenological Experience
Gowda, Mahesh Ramanna; Srinivasa, Preethi; Kumbar, Prabha S.; Ramalingaiah, Vinay Hosagavi; Muthyalappa, Chandrashekar; Durgoji, Sumit
2016-01-01
Ketamine, a primarily FDA-approved anaesthetic agent is also used as recreational drug. Based on preclinical findings and later the clinical observations it is noted to have rapid antidepressant effect due to its mechanisms related to NMDA antagonism. In spite of established evidence of ketamine being effective in depression with significant role in treatment resistant cases as well, there was absolute dearth of literature regarding its utility in grief-related disorders. In this context we present a case of 28-year-old graduate male who presented to us in complicated grief following death of his wife due to obstetric complications. With the patient and immediate family members consenting for use of ketamine as off-label use, patient had single IV infusion of ketamine following which he had unique phenomenological experience ultimately resolving his grief in few minutes. Through this case we highlight the enormous therapeutic promise of ketamine in complicated grief. PMID:27011405
Longitudinal Effects on Early Adolescent Language: A Twin Study
DeThorne, Laura Segebart; Smith, Jamie Mahurin; Betancourt, Mariana Aparicio; Petrill, Stephen A.
2016-01-01
Purpose We evaluated genetic and environmental contributions to individual differences in language skills during early adolescence, measured by both language sampling and standardized tests, and examined the extent to which these genetic and environmental effects are stable across time. Method We used structural equation modeling on latent factors to estimate additive genetic, shared environmental, and nonshared environmental effects on variance in standardized language skills (i.e., Formal Language) and productive language-sample measures (i.e., Productive Language) in a sample of 527 twins across 3 time points (mean ages 10–12 years). Results Individual differences in the Formal Language factor were influenced primarily by genetic factors at each age, whereas individual differences in the Productive Language factor were primarily due to nonshared environmental influences. For the Formal Language factor, the stability of genetic effects was high across all 3 time points. For the Productive Language factor, nonshared environmental effects showed low but statistically significant stability across adjacent time points. Conclusions The etiology of language outcomes may differ substantially depending on assessment context. In addition, the potential mechanisms for nonshared environmental influences on language development warrant further investigation. PMID:27732720
40 CFR 464.36 - Pretreatment standards for new sources.
Code of Federal Regulations, 2014 CFR
2014-07-01
... that are casting primarily gray iron where greater than 1,784 tons of metal are poured per year. PSNS... primarily gray iron where equal to or less than 1,784 tons of metal are poured per year. PSNS Pollutant or pollutant property Maximum for any 1 day Maximum for monthly average kg/1,000 kkg (pounds per million pounds...
Insect and Canker Disease Impact in Cottonwood Nurseries
J. D. Solomon; J. R. Cook; F. L. Oliveria; T. H. Filer
1976-01-01
Insects (primarily cottonwood leaf beetle) reduced height growth in nurseries an average of 48.8 cm (19 in) per switch. Such a growth loss would mean a 20-25 percent drop in cuttings produced. In a survey of nine nursery plantings, cull due to borers (primarily clearwing borers)and disease cankers reduced the number of potential cuttings from 1.6 to 25.6 percent and...
Hilderbrand, Grant V.; Jenkins, S.G.; Schwartz, C.C.; Hanley, Thomas A.; Robbins, C.T.
1999-01-01
The influence of seasonal dietary meat intake on changes in body mass and composition in wild and captive brown bears (Ursus arctos) was investigated because the importance and availability of meat to brown bear populations is currently an important management consideration in several North American ecosystems. Adult female brown bears on the Kenai Peninsula, Alaska, utilized meat heavily in both spring and fall. Meat accounted for 76.2 ± 26.0% (mean ± 1 SD; primarily moose carrion and calves) of assimilated carbon and nitrogen in the spring and 80.4 ± 22.2% (primarily salmon) in the fall. Mass increases in the spring (71.8 ± 28.2%) were mostly lean body mass, but increases in the fall (81.0 ± 19.5%) were primarily fat. Daily intake by captive brown bears fed meat ad libitum during 12-day trials was positively related to body mass. Mass change was positively related to intake in both seasons, but the composition of the gain varied by season, with spring gains primarily lean body mass (64.2 ± 9.4%), while fall gains were 78.8 ± 19.6% lipid. Absolute rates of gain by wild bears occasionally equaled, but were usually much less than, those of captive bears. This was likely due to a combination of factors, which included the time required to locate and handle meat resources, the limited availability of or access to meat resources, and (or) the duration of meat resource availability. Estimated intake by bears not feeding selectively on high-energy components of moose and salmon were 8.5 ± 1.5 kg/day and 541 ± 156 kg/year and 10.8 ± 4.6 kg/day and 1003 ± 489 kg/year, respectively. Intake would drop by as much as 58% for bears feeding exclusively on salmon roe. Management strategies for areas with brown bears that consume significant amounts of meat should address the perpetuation and availability of these meat resources.
Equal Protection and Due Process: Contrasting Methods of Review under Fourteenth Amendment Doctrine.
ERIC Educational Resources Information Center
Hughes, James A.
1979-01-01
Argues that the Court has, at times, confused equal protection and due process methods of review, primarily by employing interest balancing in certain equal protection cases that should have been subjected to due process analysis. Available from Harvard Civil Rights-Civil Liberties Law Review, Harvard Law School, Cambridge, MA 02138; sc $4.00.…
Partial diel migration: A facultative migration underpinned by long-term inter-individual variation.
Harrison, Philip M; Gutowsky, Lee F G; Martins, Eduardo G; Patterson, David A; Cooke, Steven J; Power, Michael
2017-09-01
The variations in migration that comprise partial diel migrations, putatively occur entirely as a consequence of behavioural flexibility. However, seasonal partial migrations are increasingly recognised to be mediated by a combination of reversible plasticity in response to environmental variation and individual variation due to genetic and environmental effects. Here, we test the hypothesis that while partial diel migration heterogeneity occurs primarily due to short-term within-individual flexibility in behaviour, long-term individual differences in migratory behaviour also underpin this migration variation. Specifically, we use a hierarchical behavioural reaction norm approach to partition within- and among-individual variation in depth use and diel plasticity in depth use, across short- and long-term time-scales, in a group of 47 burbot (Lota lota) tagged with depth-sensing acoustic telemetry transmitters. We found that within-individual variation at the among-dates-within-seasons and among-seasons scale, explained the dominant proportion of phenotypic variation. However, individuals also repeatedly differed in their expression of migration behaviour over the 2 year study duration. These results reveal that diel migration variation occurs primarily due to short-term within-individual flexibility in depth use and diel migration behaviour. However, repeatable individual differences also played a key role in mediating partial diel migration. These findings represent a significant advancement of our understanding of the mechanisms generating the important, yet poorly understood phenomena of partial diel migration. Moreover, given the pervasive occurrence of diel migrations across aquatic taxa, these findings indicate that individual differences have an important, yet previously unacknowledged role in structuring the temporal and vertical dynamics of aquatic ecosystems. © 2017 The Authors. Journal of Animal Ecology © 2017 British Ecological Society.
The Air-Carbon-Water Synergies and Trade-Offs in China's Natural Gas Industry
NASA Astrophysics Data System (ADS)
Qin, Yue
China's coal-dominated energy structure is partly responsible for its domestic air pollution, local water stress, and the global climate change. Primarily to tackle the haze issue, China has been actively promoting a nationwide coal to natural gas end-use switch. My dissertation focuses on evaluating the air quality, carbon, and water impacts and their interactions in China's natural gas industry. Chapter 2 assesses the lifecycle climate performance of China's shale gas in comparison to coal based on stage-level energy consumption and methane leakage rates. I find the mean lifecycle carbon footprint of shale gas is about 30-50% lower than that of coal under both 20 year and 100 year global warming potentials (GWP20 and GWP100). However, primarily due to large uncertainties in methane leakage, the lifecycle carbon footprint of shale gas in China could be 15-60% higher than that of coal across sectors under GWP20. Chapter 3 evaluates the air quality, human health, and the climate impacts of China's coal-based synthetic natural gas (SNG) development. Based on earlier 2020 SNG production targets, I conduct an integrated assessment to identify production technologies and end-use applications that will bring as large air quality and health benefits as possible while keeping carbon penalties as small as possible. I find that, due to inefficient and uncontrolled coal combustion in households, allocating currently available SNG to the residential sector proves to be the best SNG allocation option. Chapter 4 compares the air quality, carbon, and water impacts of China's six major gas sources under three end-use substitution scenarios, which are focused on maximizing air pollutant emission reductions, CO 2 emission reductions, and water stress index (WSI)-weighted water consumption reductions, respectively. I find striking national air-carbon/water trade-offs due to SNG, which also significantly increases water demands and carbon emissions in regions already suffering from severe water stress and having the largest per capita carbon footprint. Gas sources other than SNG may bring national air-carbon-water co-benefits. However, end-use deployment can cause enormous variations in air quality, carbon, and water impacts, with notable air-carbon synergies but air-water trade-offs.
The Role of the Corps Air Defense Artillery Brigade
1990-06-01
literature pertaining to the corps air defense artillery brigades. In most air defense artillery field manuals (FM), reference to a unit above brigade...available information and focus on the information which directly applies to the thesis. I primarily used U.S. Army field manuals to research the...The brigade will be primarily operating in a decentralized mode due to the inevitable communications breakdowns that will occur. Therefore, manual
Land use effects on green water fluxes from agricultural production in Mato Grosso, Brazil
NASA Astrophysics Data System (ADS)
Lathuilliere, M. J.; Johnson, M. S.; Donner, S. D.
2010-12-01
The blue water/green water paradigm is increasingly used to differentiate between subsequent routing of precipitation once it reaches the soil. “Blue” water is that which infiltrates deep in the soil to become streams and aquifers, while “green” water is that which remains in the soil and is either evaporated (non-productive green water) or transpired by plants (productive green water). This differentiation in the fate of precipitation has provided a new way of thinking about water resources, especially in agriculture for which better use of productive green water may help to relieve stresses from irrigation (blue water). The state of Mato Grosso, Brazil, presents a unique case for the study of green water fluxes due to an expanding agricultural land base planted primarily to soybean, maize, sugar cane, and cotton. These products are highly dependent on green water resources in Mato Grosso where crops are almost entirely rain-fed. We estimate the change in green water fluxes from agricultural expansion for the 2000-2008 period in the state of Mato Grosso based on agricultural production data from the Instituto Brasileiro de Geografia e Estatísticas and a modified Penman-Monteith equation. Initial results for seven municipalities suggest an increase in agricultural green water fluxes, ranging from 1-10% per year, due primarily to increases in cropped areas. Further research is underway to elucidate the role of green water flux variations from land use practices on the regional water cycle.
Olds, David L; Kitzman, Harriet J; Cole, Robert E; Hanks, Carole A; Arcoleo, Kimberly J; Anson, Elizabeth A; Luckey, Dennis W; Knudtson, Michael D; Henderson, Charles R; Bondy, Jessica; Stevenson, Amanda J
2010-05-01
To test, among an urban primarily African American sample, the effects of prenatal and infancy home visiting by nurses on mothers' fertility, partner relationships, and economic self-sufficiency and on government spending through age 12 years of their firstborn child. Randomized controlled trial. Public system of obstetric and pediatric care in Memphis, Tennessee. A total of 594 urban primarily African American economically disadvantaged mothers (among 743 who registered during pregnancy). Intervention Prenatal and infancy home visiting by nurses. Mothers' cohabitation with and marriage to the child's biological father, intimate partner violence, duration (stability) of partner relationships, role impairment due to alcohol and other drug use, use and cost of welfare benefits, arrests, mastery, child foster care placements, and cumulative subsequent births. By the time the firstborn child was 12 years old, nurse-visited mothers compared with control subjects reported less role impairment owing to alcohol and other drug use (0.0% vs 2.5%, P = .04), longer partner relationships (59.58 vs 52.67 months, P = .02), and greater sense of mastery (101.04 vs 99.60, P = .005). During this 12-year period, government spent less per year on food stamps, Medicaid, and Aid to Families with Dependent Children and Temporary Assistance for Needy Families for nurse-visited than control families ($8772 vs $9797, P = .02); this represents $12 300 in discounted savings compared with a program cost of $11 511, both expressed in 2006 US dollars. No statistically significant program effects were noted on mothers' marriage, partnership with the child's biological father, intimate partner violence, alcohol and other drug use, arrests, incarceration, psychological distress, or reports of child foster care placements. The program improved maternal life course and reduced government spending among children through age 12 years.
Musculoskeletal injuries among Malaysian badminton players.
Shariff, A H; George, J; Ramlan, A A
2009-11-01
The purpose of this study was to investigate the pattern of musculoskeletal injuries sustained by Malaysian badminton players. This is a retrospective case notes review of all badminton players who attended the National Sports Institute (NSI) Clinic, Kuala Lumpur, Malaysia, and were diagnosed with musculoskeletal injuries. In a two and a half year period, from January 2005 to June 2007, 469 musculoskeletal injuries were diagnosed among badminton players at the NSI Clinic. The mean age of the players who attended the clinic was 19.2 (range 13-52) years. Approximately 60 percent of the injuries occurred in players younger than 20 years of age. The majority of injuries (91.5 percent) were categorised as mild overuse injury and mostly involved the knee. The majority of the injuries sustained by badminton players in this study were due to overuse, primarily in the knee. The majority of the injuries were diagnosed in younger players and occurred during training/practice sessions. There was no difference in terms of incidence and types of injuries between the genders.
[Foreign bodies aspiration in pediatrics. 15-year experience. Analysis of 337 cases].
Aguirre Vázquez, I R; Blanco Rodríguez, G; Penchyna Grub, J; Teyssier Morales, G; Serrano Salas, A L
2013-01-01
Foreign body aspiration is a pediatric urgency that occurs primarily between 1 and 3 years old. The aim of this paper is to present the symptomatology, clinical and radiological findings, and the therapeutic used in our hospital with patients with foreign body aspiration diagnosis from 1995 until 2011. Patient's age was between 0 and 16 years old. We included 337 patients; where males predominate (205). The medium age was 23 months. The most frequent foreign bodies founded were seeds (192) in 57% and metallic objects in 18.3%. Cough (74.5%), dyspnea (70%), cyanosis (42.4%) and stridor (26%), were the main symptoms. Right bronchus was the most frequent localization (37.7%). In 21% of the patients the reference diagnostic was wrong due to treating it as a respiratory infection. All foreign bodies were extracted by rigid bronchoscopy. No deaths were reported in any proceeding. In our experience, infants are the most affected group, and the primordial symptoms are cough and dyspnea. Organic objects had the highest prevalence of aspiration.
Routine operation of an Elliott 903 computer in a clinical chemistry laboratory
Whitby, L. G.; Simpson, D.
1973-01-01
Experience gained in the last four years concerning the capabilities and limitations of an 8K Elliott 903 (18-bit word) computer with magnetic tape backing store in the routine operation of a clinical chemistry laboratory is described. Designed as a total system, routine operation has latterly had to be confined to data acquisition and process control functions, due primarily to limitations imposed by the choice of hardware early in the project. In this final report of a partially successful experiment the opportunity is taken to review mistakes made, especially at the start of the project, to warn potential computer users of pitfalls to be avoided. PMID:4580240
Recent Earth oblateness variations: unraveling climate and postglacial rebound effects.
Dickey, Jean O; Marcus, Steven L; de Viron, Olivier; Fukumori, Ichiro
2002-12-06
Earth's dynamic oblateness (J2) has been decreasing due to postglacial rebound (PGR). However, J2 began to increase in 1997, indicating a pronounced global-scale mass redistribution within Earth's system. We have determined that the observed increases in J2 are caused primarily by a recent surge in subpolar glacial melting and by mass shifts in the Southern, Pacific, and Indian oceans. When these effects are removed, the residual trend in J2 (-2.9 x 10(-11) year-1) becomes consistent with previous estimates of PGR from satellite and eclipse data. The climatic significance of these rapid shifts in glacial and oceanic mass, however, remains to be investigated.
McGinley, Jacqueline M
2016-04-01
Individuals with intellectual and developmental disabilities are living unprecedentedly longer lives primarily due to the long-term benefits of the deinstitutionalization movement and widespread improvements in health outcomes. However, the consequences of this protracted aging process are significant, complex, and often poor not only for the individuals and their caregivers but for the mainstream healthcare community. This article will explore, utilizing a constructionist perspective, how these challenges evolved from a nonissue to an impending crisis in less than 25 years. Additionally, present-day efforts by researchers, policymakers, and practitioners to address these challenges will be explored and recommendations will be made for future directions.
Optimization of large matrix calculations for execution on the Cray X-MP vector supercomputer
NASA Technical Reports Server (NTRS)
Hornfeck, William A.
1988-01-01
A considerable volume of large computational computer codes were developed for NASA over the past twenty-five years. This code represents algorithms developed for machines of earlier generation. With the emergence of the vector supercomputer as a viable, commercially available machine, an opportunity exists to evaluate optimization strategies to improve the efficiency of existing software. This result is primarily due to architectural differences in the latest generation of large-scale machines and the earlier, mostly uniprocessor, machines. A sofware package being used by NASA to perform computations on large matrices is described, and a strategy for conversion to the Cray X-MP vector supercomputer is also described.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bartlett, J. E.; Margolis, R. M.; Jennings, C. E.
To examine how the financial crisis has impacted expectations of photovoltaic production, demand and pricing over the next several years, we surveyed the market forecasts of industry analysts that had issued projections in 2008 and 2009. We find that the financial crisis has had a significant impact on the PV industry, primarily through increasing the cost and reducing the availability of investment into the sector. These effects have been more immediately experienced by PV installations than by production facilities, due to the different types and duration of investments, and thus PV demand has been reduced by a greater proportion thanmore » PV production. By reducing demand more than production, the financial crisis has accelerated previously expected PV overcapacity and resulting price declines.« less
Profile of an individual supporting member
NASA Astrophysics Data System (ADS)
During the past 2 years, the number of Individual Supporting Members in AGU has more than doubled. This increase in interest is primarily due to the AGU-GIFT program and its efforts to seek the voluntary support of all members. Your response has been encouraging, and we believe the number can be doubled again in the next 18 months.Who is the typical Individual Supporting Member? The first step in the development of a “profile” was to find the age pattern. The eldest was born in 1892—Congratulations on your 90th year!—and the youngest in 1948. One would hardly expect to find a Gaussian distribution. In fact there was no evidence of a “peak,” but 50% were born between 1910 and 1930—with the median age being 62—just beginning to harvest the fruits of senior citizenship. For comparison, the median age for the total membership of AGU is 42.
FY96-98 Summary Report Mercury: Next Generation Laser for High Energy Density Physics SI-014
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bayramian, A.; Beach, R.; Bibeau, C.
The scope of the Mercury Laser project encompasses the research, development, and engineering required to build a new generation of diode-pumped solid-state lasers for Inertial Confinement Fusion (ICF). The Mercury Laser will be the first integrated demonstration of laser diodes, crystals, and gas cooling within a scalable laser architecture. This report is intended to summarize the progress accomplished during the first three years of the project. Due to the technological challenges associated with production of 900 nm diode-bars, heatsinks, and high optical-quality Yb:S-FAP crystals, the initial focus of the project was primarily centered on the R&D in these three areas.more » During the third year of the project, the R&D continued in parallel with the development of computer codes, partial activation of the laser, component testing, and code validation where appropriate.« less
Comparison of Field Measurements to Methane Emissions Models at a New Landfill
Due to both technical and economic limitations, estimates of methane emissions from landfills rely primarily on models. While models are easy to implement, there is uncertainty due to the use of parameters that are difficult to validate. The objective of this research was to comp...
Elucidating the Population Dynamics of Japanese Knotweed Using Integral Projection Models
Dauer, Joseph T.; Jongejans, Eelke
2013-01-01
Plant demographic studies coupled with population modeling are crucial components of invasive plant management because they inform managers when in a plant’s life cycle it is most susceptible to control efforts. Providing land managers with appropriate data can be especially challenging when there is limited data on potentially important transitions that occur belowground. For 2 years, we monitored 4 clonal Japanese knotweed ( Polygonum cuspidatum ) infestations for emergence, survival, shoot height until leaf senescence, dry shoot biomass after senescence, and rhizome connections for 424 shoots. We developed an integral projection model using both final autumn shoot height and shoot biomass as predictors of survival between years, growth from year to year, and number of rhizomes produced by a shoot (fecundity). Numbers of new shoots within an infestation (population growth rate λ) were projected to increase 13-233% in a year, with the greatest increase at the most frequently disturbed site. Elasticity analysis revealed population growth at 3 of the 4 sites was primarily due to ramet survival between years and to year-to-year growth in shoot height and shoot biomass. Population growth at the fourth site, the most disturbed, was due to the large production of new rhizomes and associated shoots. In contrast to previous studies, our excavation revealed that most of the shoots were not interconnected, suggesting rhizome production may be limited by the size or age of the plants, resource availability, disturbance frequency, or other factors. Future integration of plant population models with more data on belowground growth structures will clarify the critical stages in Japanese knotweed life cycle and support land managers in their management decisions. PMID:24073249
Warming experiments elucidate the drivers of observed directional changes in tundra vegetation
Hollister, Robert D; May, Jeremy L; Kremers, Kelseyann S; Tweedie, Craig E; Oberbauer, Steven F; Liebig, Jennifer A; Botting, Timothy F; Barrett, Robert T; Gregory, Jessica L
2015-01-01
Few studies have clearly linked long-term monitoring with in situ experiments to clarify potential drivers of observed change at a given site. This is especially necessary when findings from a site are applied to a much broader geographic area. Here, we document vegetation change at Barrow and Atqasuk, Alaska, occurring naturally and due to experimental warming over nearly two decades. An examination of plant cover, canopy height, and community indices showed more significant differences between years than due to experimental warming. However, changes with warming were more consistent than changes between years and were cumulative in many cases. Most cases of directional change observed in the control plots over time corresponded with a directional change in response to experimental warming. These included increases in canopy height and decreases in lichen cover. Experimental warming resulted in additional increases in evergreen shrub cover and decreases in diversity and bryophyte cover. This study suggests that the directional changes occurring at the sites are primarily due to warming and indicates that further changes are likely in the next two decades if the regional warming trend continues. These findings provide an example of the utility of coupling in situ experiments with long-term monitoring to accurately document vegetation change in response to global change and to identify the underlying mechanisms driving observed changes. PMID:26140204
NASA Astrophysics Data System (ADS)
Hong, Xiaowei; Lu, Riyu; Li, Shuanglin
2018-04-01
In previous work, a significant relationship was identified between the meridional displacement of the Asian westerly jet (JMD) and the Silk Road Pattern (SRP) in summer. The present study reveals that this relationship is robust in northward JMD years but absent in southward JMD years. In other words, the amplitude of the SRP increases with northward displacement of the jet but shows little change with southward displacement. Further analysis indicates that, in northward JMD years, the Rossby wave source (RWS) anomalies, which are primarily contributed by the planetary vortex stretching, are significantly stronger around the entrance of the Asian jet, i.e., the Mediterranean Sea-Caspian Sea area, with the spatial distribution being consistent with that related to the SRP. By contrast, in southward JMD years, the RWS anomalies are much weaker. Therefore, this study suggests that the RWS plays a crucial role in inducing the asymmetry of the JMD-SRP relationship. The results imply that climate anomalies may be stronger in strongly northward-displaced JMD years due to the concurrence of the JMD and SRP, and thus more attention should be paid to these years.
Interannual Variability of Boreal Summer Rainfall in the Equatorial Atlantic
NASA Technical Reports Server (NTRS)
Gu, Guojun; Adler, Robert F.
2007-01-01
Tropical Atlantic rainfall patterns and variation during boreal summer [June-July-August (JJA)] are quantified by means of a 28-year (1979-2006) monthly precipitation dataset from the Global Precipitation Climatology Project (GPCP). Rainfall variability during boreal spring [March-April-May (MAM)] is also examined for comparison in that the most intense interannual variability is usually observed during this season. Comparable variabilities in the Intertropical Convergence Zone (ITCZ) strength and the basin-mean rainfall are found during both seasons. Interannual variations in the ITCZ's latitudinal location during JJA however are generally negligible, in contrasting to intense year-to-year fluctuations during MAM. Sea surface temperature (SST) oscillations along the equatorial region (usually called the Atlantic Nino events) and in the tropical north Atlantic (TNA) are shown to be the two major local factors modulating the tropical Atlantic climate during both seasons. During MAM, both SST modes tend to contribute to the formation of an evident interhemispheric SST gradient, thus inducing anomalous shifting of the ITCZ and then forcing a dipolar structure of rainfall anomalies across the equator primarily in the western basin. During JJA the impacts however are primarily on the ITCZ strength likely due to negligible changes in the ITCZ latitudinal location. The Atlantic Nino reaches its peak in JJA, while much weaker SST anomalies appear north of the equator in JJA than in MAM, showing decaying of the interhemispheric SST mode. SST anomalies in the tropical central-eastern Pacific (the El Nino events) have a strong impact on tropical Atlantic including both the tropical north Atlantic and the equatorial-southern Atlantic. However, anomalous warming in the tropical north Atlantic following positive SST anomalies in the tropical Pacific disappears during JJA because of seasonal changes in the large-scale circulation cutting off the ENSO influence passing through the mid-latitudes. Hence the anomalies associated with the tropical Pacific during JJA are forced through an anomalous Walker circulation primarily working on the western basin, and likely a lagged oceanic response in the equatorial region.
Kohlsdorf, Katja; Nunziata, Adriana; Funcke, Jan-Bernd; Brandt, Stephanie; von Schnurbein, Julia; Vollbach, Heike; Lennerz, Belinda; Fritsch, Maria; Greber-Platzer, Susanne; Fröhlich-Reiterer, Elke; Luedeke, Manuel; Borck, Guntram; Debatin, Klaus-Michael; Fischer-Posovszky, Pamela; Wabitsch, Martin
2018-02-27
To evaluate whether early childhood body mass index (BMI) is an appropriate indicator for monogenic obesity. A cohort of n = 21 children living in Germany or Austria with monogenic obesity due to congenital leptin deficiency (group LEP, n = 6), leptin receptor deficiency (group LEPR, n = 6) and primarily heterozygous MC4 receptor deficiency (group MC4R, n = 9) was analyzed. A control group (CTRL) was defined that consisted of n = 22 obese adolescents with no mutation in the above mentioned genes. Early childhood (0-5 years) BMI trajectories were compared between the groups at selected time points. The LEP and LEPR group showed a tremendous increase in BMI during the first 2 years of life with all patients displaying a BMI >27 kg/m 2 (27.2-38.4 kg/m 2 ) and %BMI P95 (percentage of the 95th percentile BMI for age and sex) >140% (144.8-198.6%) at the age of 2 years and a BMI > 33 kg/m 2 (33.3-45.9 kg/m 2 ) and %BMI P95 > 184% (184.1-212.6%) at the age of 5 years. The MC4R and CTRL groups had a later onset of obesity with significantly lower BMI values at both time points (p < 0.01). As result of the investigation of early childhood BMI trajectories in this pediatric cohort with monogenic obesity we suggest that BMI values >27.0 kg/m 2 or %BMI P95 > 140% at the age of 2 years and BMI values >33.0 kg/m 2 or %BMI P95 > 184% at the age of 5 years may be useful cut points to identify children who should undergo genetic screening for monogenic obesity due to functionally relevant mutations in the leptin gene or leptin receptor gene.
Twenty-three years of height changes on Antarctic Peninsula ice shelves
NASA Astrophysics Data System (ADS)
Adusumilli, S.; Siegfried, M. R.; Paolo, F. S.; Fricker, H. A.; Padman, L.
2017-12-01
Over the past few decades, several ice shelves in the Antarctic Peninsula (AP), the northernmost region of Antarctica, have collapsed or undergone significant retreat. While the disintegration of these ice shelves appears to be linked primarily to hydrofracture initiated by widespread surface melting, it has also been proposed that some of these ice shelves could have weakened prior to collapse due to increased basal melt rates induced by thermal ocean forcing. To determine the long-term evolution of ice shelves in this region, we compiled data from four radar altimeters (ERS-1, ERS-2, Envisat, and CryoSat-2) spanning twenty-three years (1994-2017). Over Larsen C, the largest AP ice shelf, a surface lowering of around 1 m between 1992 and 2009 has been partially offset by a height increase of around 0.75 m between 2009 and 2017. We use four independent, repeat airborne laser altimetry surveys from NASA's Operation IceBridge to confirm the recent height increase, and a firn densification model (IMAU-FDM) forced by a regional atmospheric model (RACMO), to show that the recent height increase is primarily due to density changes in the firn column. In contrast, George VI Ice Shelf in the Bellingshausen Sea remains in a state of continuous thinning through excess basal melting attributed to higher fluxes of ocean heat under the ice shelf. Changes such as these, which can occur on seasonal to decadal timescales, can potentially impact the dynamics of the grounded ice sheet behind the floating ice shelves, consequently affecting sea-level rise. Therefore, it is vital to continue the long-term, uninterrupted monitoring of ice shelves through the modern satellite and airborne altimetry missions, and lengthen our existing time series to investigate the climate drivers causing changes in the ice shelves from above (accumulation and density changes) and below (basal melting).
Results of Mechanical Testing for Pyroceram(tm) Glass-Ceramic
NASA Technical Reports Server (NTRS)
Choi, Sung R.; Gyekenyesi, John P.
2003-01-01
Mechanical testing for Pyroceram (trademark) 9606 glass-ceramic fabricated by Corning was conducted to determine mechanical properties of the material including slow crack growth.Valid testing was not achieved in tension, compression, and shear testing due to inappropriate test specimen configurations provided and primarily due to the existence of fortified layer( in tension).
On the Regulation of the Pacific Warm Pool Temperature
NASA Technical Reports Server (NTRS)
Chou, Ming-Dah; Chou, Sue-Hsien; Chan, Pui-King; Lau, William K. M. (Technical Monitor)
2002-01-01
In the tropical western Pacific, regions of the highest sea surface temperature (SST) and the largest cloud cover are found to have the largest surface heating, primarily due to the weak evaporative cooling associated with weak winds. This situation is in variance with the suggestions that the temperature in the Pacific warm pool is regulated either by the reduced solar heating due to an enhanced cloudiness or by the enhanced evaporative cooling due to an elevated SST. It is clear that an enhanced surface heating in an enhanced convection region is not sustainable and must be interrupted by variations in large-scale atmospheric circulation. As the deep convective regions shift away from regions of high SST due primarily to seasonal variation and secondarily to interannual variation of the large-scale atmospheric and oceanic circulation, both trade wind and evaporative cooling in the high SST region increase, leading to a reduction in SST. We conclude that the evaporative cooling associated with the seasonal and interannual variations of trade winds in the primary factor that prevent the warm pool SST from increasing to a value much higher than what is observed.
Review of ultra-high density optical storage technologies for big data center
NASA Astrophysics Data System (ADS)
Hao, Ruan; Liu, Jie
2016-10-01
In big data center, optical storage technologies have many advantages, such as energy saving and long lifetime. However, how to improve the storage density of optical storage is still a huge challenge. Maybe the multilayer optical storage technology is the good candidate for big data center in the years to come. Due to the number of layers is primarily limited by transmission of each layer, the largest capacities of the multilayer disc are around 1 TB/disc and 10 TB/ cartridge. Holographic data storage (HDS) is a volumetric approach, but its storage capacity is also strictly limited by the diffractive nature of light. For a holographic disc with total thickness of 1.5mm, its potential capacities are not more than 4TB/disc and 40TB/ cartridge. In recent years, the development of super resolution optical storage technology has attracted more attentions. Super-resolution photoinduction-inhibition nanolithography (SPIN) technology with 9 nm feature size and 52nm two-line resolution was reported 3 years ago. However, turning this exciting principle into a real storage system is a huge challenge. It can be expected that in the future, the capacities of 10TB/disc and 100TB/cartridge can be achieved. More importantly, due to breaking the diffraction limit of light, SPIN technology will open the door to improve the optical storage capacity steadily to meet the need of the developing big data center.
Eco-driving: behavioural pattern change in Polish passenger vehicle drivers
NASA Astrophysics Data System (ADS)
Czechowski, Piotr Oskar; Oniszczuk-Jastrząbek, Aneta; Czuba, Tomasz
2018-01-01
In Poland, as in the rest of Europe, air quality depends primarily on emissions from municipal, domestic and road transport sources. The problems of appropriate air quality are especially important within urban areas due to numerous sources of emissions being concentrated in relatively small spaces in both large cities and small/medium-sized towns. Due to the steadily increasing share of urban population in the overall number of population, the issue of providing clean air will over the years become a more significant problem for human health, and therefore a stronger incentive to intensify research. The key challenge faced by a modern society is, therefore, to limit harmful substance emissions in order to minimise the contribution of transport to pollution and health hazards. Increasingly stringent emission standards are being imposed on car manufacturers; on the other hand, scant regard is paid to the issue of drivers, i.e. how they can help reduce emissions and protect their life and health by applying eco-driving rules.
Brightening and Volatile Distribution Within Shackleton Crater Observed by the LRO Laser Altimeter.
NASA Technical Reports Server (NTRS)
Smith, D. E.; Zuber, M. T.; Head, J. W.; Neumann, G. A.; Mazarico, E.; Torrence, M. H.; Aharonson, O.; Tye, A. R.; Fassett, C. I.; Rosengurg, M. A.;
2012-01-01
Shackleton crater, whose interior lies largely in permanent shadow, is of interest due to its potential to sequester volatiles. Observations from the Lunar Orbiter Laser Altimeter onboard the Lunar Reconnaissance Orbiter have enabled an unprecedented topographic characterization, revealing Shackleton to be an ancient, unusually well-preserved simple crater whose interior walls are fresher than its floor and rim. Shackleton floor deposits are nearly the same age as the rim, suggesting little floor deposition since crater formation over 3 billion years ago. At 1064 nm the floor of Shackleton is brighter than the surrounding terrain and the interiors of nearby craters, but not as bright as the interior walls. The combined observations are explainable primarily by downslope movement of regolith on the walls exposing fresher underlying material. The relatively brighter crater floor is most simply explained by decreased space weathering due to shadowing, but a 1-mm-thick layer containing approx 20% surficial ice is an alternative possibility.
Texture evolution during nitinol martensite detwinning and phase transformation
NASA Astrophysics Data System (ADS)
Cai, S.; Schaffer, J. E.; Ren, Y.; Yu, C.
2013-12-01
Nitinol has been widely used to make medical devices for years due to its unique shape memory and superelastic properties. However, the texture of the nitinol wires has been largely ignored due to inherent complexity. In this study, in situ synchrotron X-ray diffraction has been carried out during uniaxial tensile testing to investigate the texture evolution of the nitinol wires during martensite detwinning, variant reorientation, and phase transformation. It was found that the thermal martensitic nitinol wire comprised primarily an axial (1¯20), (120), and (102)-fiber texture. Detwinning initially converted the (120) and (102) fibers to the (1¯20) fiber and progressed to a (1¯30)-fiber texture by rigid body rotation. At strains above 10%, the (1¯30)-fiber was shifted to the (110) fiber by (21¯0) deformation twinning. The austenitic wire exhibited an axial (334)-fiber, which transformed to the near-(1¯30) martensite texture after the stress-induced phase transformation.
[A case of phenytoin intoxication caused by interaction between phenytoin and capecitabine].
Taguchi, Yoshiharu; Takashima, Shutaro; Tanaka, Kortaro
2015-02-01
We report a case of phenytoin intoxication caused by an interaction between phenytoin and capecitabine. A 41-year-old woman was started on phenytoin (200 mg p.o. daily) for convulsive attacks due to breast cancer brain metastasis. Three months later, chemotherapy with 2,400 mg/d capecitabine (3 weeks on and 1 week off) and 1,250 mg/d lapatinib was initiated for the treatment of breast cancer. Approximately 10 weeks after starting chemotherapy, the patient began to complain of nausea, vomiting, and unsteadiness, and she was admitted to our hospital. Since her serum phenytoin level was more than 40 μg/mL, she was diagnosed with phenytoin intoxication. Phenytoin is metabolized in the liver, primarily by the CYP2C9 isozyme, which can be competitively inhibited by capecitabine. Thus, we determined that the patient developed phenytoin intoxication due to the interaction between phenytoin and capecitabine. This indicates the importance of considering the potential drug-drug interactions while prescribing anticancer agents and antiepileptic drugs simultaneously.
Testa, A; Stronati, L; Ranaldi, R; Spanò, M; Steinhäusler, F; Gastberger, M; Hubmer, A; Ptitskaya, L; Akhmetov, M
2001-06-01
The Semipalatinsk region (Kazakhstan Republic) has been affected by extensive radioactive contamination due to more than 450 nuclear tests of which almost 100 were exploded in the atmosphere. The present results refer to cytogenetic assessments in a study cohort of the population of Dolon, a settlement located on the NE boundary of the nuclear weapon test site, which was exposed to elevated doses of ionising radiation primarily due to the first Soviet nuclear test in 1949. Conventional cytogenetic analyses were carried out on 21 blood samples from individuals (more than 50 years old) living in Dolon since the very beginning of nuclear testing. A matched control group included 20 individuals living in non-contaminated areas. Higher frequencies of chromosome aberrations were found in the Dolon cohort compared to the control group, even though they remain within the range of the background levels reported for large normal human population studies on elderly individuals.
NASA Astrophysics Data System (ADS)
Sarkar, Ritabrata; Chakrabarti, Sandip K.; Pal, Partha Sarathi; Bhowmick, Debashis; Bhattacharya, Arnab
2017-09-01
Cosmic ray flux in our planetary system is primarily modulated by solar activity. Radiation effects of cosmic rays on the Earth strongly depend on latitude due to the variation of the geomagnetic field strength. To study these effects we carried out a series of measurements of the radiation characteristics in the atmosphere due to cosmic rays from various places (geomagnetic latitude: ∼14.50°N) in West Bengal, India, located near the Tropic of Cancer, for several years (2012-2016) particularly covering the solar maximum in the 24th solar cycle. We present low energy (15-140 keV) secondary radiation measurement results extending from the ground till the near space (∼40 km) using a scintillator detector on board rubber weather balloons. We also concentrate on the cosmic ray intensity at the Regener-Pfotzer maxima and find a strong anti-correlation between this intensity and the solar activity even at low geomagnetic latitudes.
2002-12-13
This portion of NASA Mars Odyssey image covers NASA Viking 2 landing site shown with the X. The second landing on Mars took place September 3, 1976 in Utopia Planitia. The exact location of Lander 2 is not as well established as Lander 1 because there were no clearly identifiable features in the lander images as there were for the site of Lander 1. The Utopia landing site region contains pedestal craters, shallow swales and gentle ridges. The crater Goldstone was named in honor of the Tracking Station in the desert of California. The two Viking Landers operated for over 6 years (nearly four martian years) after landing. This one band IR (band 9 at 12.6 microns) image shows bright and dark textures, which are primarily due to differences in the abundance of rocks on the surface. The relatively cool (dark) regions during the day are rocky or indurated materials, fine sand and dust are warmer (bright). Many of the temperature variations are due to slope effects, with sun-facing slopes warmer than shaded slopes. The dark rings around several of the craters are due to the presence of rocky (cool) material ejected from the crater. These rocks are well below the resolution of any existing Mars camera, but THEMIS can detect the temperature variations they produce. Daytime temperature variations are produced by a combination of topographic (solar heating) and thermophysical (thermal inertia and albedo) effects. Due to topographic heating the surface morphologies seen in THEMIS daytime IR images are similar to those seen in previous imagery and MOLA topography. http://photojournal.jpl.nasa.gov/catalog/PIA04023
The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines
Landgraeber, Stefan; Jäger, Marcus; Jacobs, Joshua J.; Hallab, Nadim James
2014-01-01
All of the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after 15–25 years of use, due to slow progressive subtle inflammation at the bone implant interface. This inflammatory disease state is caused by implant debris acting, primarily, on innate immune cells, that is, macrophages. This slow progressive pathological bone loss or “aseptic loosening” is a potentially life-threatening condition due to the serious complications in older people (>75 yrs) of total joint replacement revision surgery. In some people implant debris (particles and ions from metals) can influence the adaptive immune system as well, giving rise to the concept of metal sensitivity. However, a consensus of studies agrees that the dominant form of this response is due to innate reactivity by macrophages to implant debris where both danger (DAMP) and pathogen (PAMP) signalling elicit cytokine-based inflammatory responses. This paper discusses implant debris induced release of the cytokines and chemokines due to activation of the innate (and the adaptive) immune system and the subsequent formation of osteolysis. Different mechanisms of implant-debris reactivity related to the innate immune system are detailed, for example, danger signalling (e.g., IL-1β, IL-18, IL-33, etc.), toll-like receptor activation (e.g., IL-6, TNF-α, etc.), apoptosis (e.g., caspases 3–9), bone catabolism (e.g., TRAP5b), and hypoxia responses (Hif1-α). Cytokine-based clinical and basic science studies are in progress to provide diagnosis and therapeutic intervention strategies. PMID:24891761
Eren, Suat; Yildirgan, Ilhan; Kantarci, A Mecit
2005-12-01
Hydatid disease presents as hydatid cysts primarily in the liver and lungs. Although hepatic hydatid cysts (HHCs) may be asymptomatic for many years, they may be symptomatic due to expansion, rupture, and pyogenic infection. Rupture of the HHC into the biliary tract is one of the most serious complications and is frequently related to overenlargement of the cyst or major trauma. Patients with this disease usually have jaundice or fever. We report an asymptomatic HHC ruptured after minor trauma. While the ruptured cyst was presented as the subdiaphragmatic gas on the chest radiography, it was detected as a large cyst with multiple daughter cysts on ultrasound, computed tomography scan, and magnetic resonance imaging.
Sources of plutonium in the atmosphere and stratosphere-troposphere mixing
Hirose, Katsumi; Povinec, Pavel P.
2015-01-01
Plutonium isotopes have primarily been injected to the stratosphere by the atmospheric nuclear weapon tests and the burn-up of the SNAP-9A satellite. Here we show by using published data that the stratospheric plutonium exponentially decreased with apparent residence time of 1.5 ± 0.5 years, and that the temporal variations of plutonium in surface air followed the stratospheric trends until the early 1980s. In the 2000s, plutonium and its isotope ratios in the atmosphere varied dynamically, and sporadic high concentrations of 239,240Pu reported for the lower stratospheric and upper tropospheric aerosols may be due to environmental events such as the global dust outbreaks and biomass burning. PMID:26508010
Optical Fiber In The Loop: Features And Applications
NASA Astrophysics Data System (ADS)
Shariati, Ross
1986-01-01
It is expected that there would be various demands for digital capacity, from a few kilobits per second for such services as facsimile, data entry, and provision of audio and graphic for teleconferencing, to about 56Kb/sec for electronic mail and integrated work stations, and higher speeds for cable television, high resolution TV, and computer-aided engineering. Fiber optics has been proven-in from an economic standpoint to provide the above-mentioned services. This is primarily due to the fact that in less than five years optical line rates have leaped from 45Mb/s to gigabit rates, therefore reducing the cost per DS3 of capacity, and the price of high quality fiber cable has taken a nosedive.
Ritchie, Marylyn D
2012-10-01
Pharmacogenomics is emerging as a popular type of study for human genetics in recent years. This is primarily due to the many success stories and high potential for translation to clinical practice. In this review, the strengths and limitations of pharmacogenomics are discussed as well as the primary epidemiologic, clinical trial, and in vitro study designs implemented. A brief discussion of molecular and analytic approaches will be reviewed. Finally, several examples of bench-to-bedside clinical implementations of pharmacogenetic traits will be described. Pharmacogenomics continues to grow in popularity because of the important genetic associations identified that drive the possibility of precision medicine.
New and Future Drug Development for Gastroesophageal Reflux Disease
Maradey-Romero, Carla
2014-01-01
Medical therapy remains the most popular treatment for gastroesophageal reflux disease (GERD). Whilst interest in drug development for GERD has declined over the last few years primarily due to the conversion of most proton pump inhibitor (PPI)'s to generic and over the counter compounds, there are still numerous areas of unmet needs in GERD. Drug development has been focused on potent histamine type 2 receptor antagonist's, extended release PPI's, PPI combination, potassium-competitive acid blockers, transient lower esophageal sphincter relaxation reducers, prokinetics, mucosal protectants and esophageal pain modulators. It is likely that the aforementioned compounds will be niched for specific areas of unmet need in GERD, rather than compete with the presently available anti-reflux therapies. PMID:24466441
NASA Technical Reports Server (NTRS)
Haertling, Gene; Grabert, Gregory; Gilmour, Phillip
1993-01-01
Results on this project over the past three years have shown that the Bi and Tl-based superconducting materials in bulk form are noticeably different from the Y-based 123 material in that superconductivity is considerably harder to achieve, maintain and reproduce. This is due primarily to the difficulty in obtaining the higher Tc phase in pure form since it commonly co-exists with other undesirable, lower Tc phases. In particular, it has been found that long processing times for calcining and firing (20 - 200 hrs.) and close control of temperatures which are very near the melting point are required in order to obtain higher proportions of the desirable, high Tc (2223) phase.
Mosaic maternal ancestry in the Great Lakes region of East Africa.
Gomes, Verónica; Pala, Maria; Salas, Antonio; Álvarez-Iglesias, Vanesa; Amorim, António; Gómez-Carballa, Alberto; Carracedo, Ángel; Clarke, Douglas J; Hill, Catherine; Mormina, Maru; Shaw, Marie-Anne; Dunne, David W; Pereira, Rui; Pereira, Vânia; Prata, Maria João; Sánchez-Diz, Paula; Rito, Teresa; Soares, Pedro; Gusmão, Leonor; Richards, Martin B
2015-09-01
The Great Lakes lie within a region of East Africa with very high human genetic diversity, home of many ethno-linguistic groups usually assumed to be the product of a small number of major dispersals. However, our knowledge of these dispersals relies primarily on the inferences of historical, linguistics and oral traditions, with attempts to match up the archaeological evidence where possible. This is an obvious area to which archaeogenetics can contribute, yet Uganda, at the heart of these developments, has not been studied for mitochondrial DNA (mtDNA) variation. Here, we compare mtDNA lineages at this putative genetic crossroads across 409 representatives of the major language groups: Bantu speakers and Eastern and Western Nilotic speakers. We show that Uganda harbours one of the highest mtDNA diversities within and between linguistic groups, with the various groups significantly differentiated from each other. Despite an inferred linguistic origin in South Sudan, the data from the two Nilotic-speaking groups point to a much more complex history, involving not only possible dispersals from Sudan and the Horn but also large-scale assimilation of autochthonous lineages within East Africa and even Uganda itself. The Eastern Nilotic group also carries signals characteristic of West-Central Africa, primarily due to Bantu influence, whereas a much stronger signal in the Western Nilotic group suggests direct West-Central African ancestry. Bantu speakers share lineages with both Nilotic groups, and also harbour East African lineages not found in Western Nilotic speakers, likely due to assimilating indigenous populations since arriving in the region ~3000 years ago.
Comparative optimism in older adults' future health expectations.
Vanderzanden, Karen; Ruthig, Joelle C
2018-05-13
Despite a common belief that health declines with age, many older adults remain optimistic about their future health. However, the longitudinal impact of personal and comparatively optimistic future health estimates (FHEs) is unclear. Among 408 older adults (M age = 70.32 years), this study identified the prevalence, source, and two-year stability of comparatively optimistic FHEs; examined demographic, psychosocial, and health correlates of comparative FHEs; and assessed the role of comparative FHEs in predicting eight-year survival odds. Nearly half of participants were comparatively optimistic due to interpersonal pessimism more so than personal optimism. Regarding stability, comparative optimism declined over the two-year period. Being younger and having more perceived control, dispositional optimism, and recent positive emotions were associated with better FHEs for oneself and a similar other. Beyond effects of age, gender, relationship status, and dispositional optimism, optimistic personal FHEs predicted eight-year survival odds. Findings have implications for predicting survival and advancing the conceptual understanding of comparative FHEs. Statement of contribution What is already known on the subject? Previous research has demonstrated that older adults tend to believe diminished health accompanies increasing age. Despite this notion, older adults remain comparatively optimistic about their health. What does this study add? The longitudinal results of the current study indicated that nearly half of participants were categorized as comparative optimists, primarily due to interpersonal pessimism. The current study demonstrated that there is little distinction between personal FHEs and those for a similar other in terms of demographic, psychosocial, and health correlates. The current study identified factors that predicted eight-year survival among older adults, such as being female, younger, in a committed relationship, and better personal FHEs. © 2018 The British Psychological Society.
USDA-ARS?s Scientific Manuscript database
Pathogen contamination of surface water is a health hazard in agricultural environments primarily due to the potential for contamination of crops. Furthermore, pathogen levels in surface water are often unreported or under reported due to difficulty with culture of the bacteria. The pathogens are of...
Trends in Intimate Partner Violence: 1980-2008
ERIC Educational Resources Information Center
Powers, Rachael A.; Kaukinen, Catherine Elizabeth
2012-01-01
Research on trends in partner violence has primarily relied on official measures of victimization focusing primarily on women's risk for intimate partner homicide. The current study uses 28 years of data from the National Crime Victimization Survey (NCVS) to examine the trends of intimate partner violence against female victims and identify…
Luo, Zhengxiang; Zhang, Yansong; Zhao, Penglai; Lu, Hucheng; Yang, Kun; Zhang, Yuhai; Zeng, Yanjun
2017-01-01
This study aimed to summarize the clinical characteristics of Rosai-Dorfman disease primarily involving the central nervous system and to explore diagnosis and treatment. We analyzed the clinical, imaging, and pathologic characteristics; treatment; and prognosis in 3 cases of Rosai-Dorfman disease primarily involving the central nervous system. We also performed a literature review. The largest of multiple intracranial lesions was totally resected, and steroid administration and radiotherapy were performed in phases for the remaining lesions. During the 1-year follow-up period, the excised lesion did not recur, and no obvious variations were observed in the other lesions. Subtotal resection was performed of the largest of another group of multiple intracranial lesions, and the residual did not show any obvious variations during the 1-year follow-up period. The isolated lesion was totally resected and did not recur during a 2-year follow-up period. Rosai-Dorfman disease with multiple lesions primarily involving the central nervous system is rare. Imaging characteristics are similar to meningiomas, and the pathological features include lymphocytes and plasma cells reaching tissue cells with large volume and abundant cytoplasm. Surgery is the preferred treatment, as the effects of steroid administration and radiotherapy are not apparent. Copyright © 2016 Elsevier Inc. All rights reserved.
Yuksel, Tugce; Michalek, Jeremy J
2015-03-17
We characterize the effect of regional temperature differences on battery electric vehicle (BEV) efficiency, range, and use-phase power plant CO2 emissions in the U.S. The efficiency of a BEV varies with ambient temperature due to battery efficiency and cabin climate control. We find that annual energy consumption of BEVs can increase by an average of 15% in the Upper Midwest or in the Southwest compared to the Pacific Coast due to temperature differences. Greenhouse gas (GHG) emissions from BEVs vary primarily with marginal regional grid mix, which has three times the GHG intensity in the Upper Midwest as on the Pacific Coast. However, even within a grid region, BEV emissions vary by up to 22% due to spatial and temporal ambient temperature variation and its implications for vehicle efficiency and charging duration and timing. Cold climate regions also encounter days with substantial reduction in EV range: the average range of a Nissan Leaf on the coldest day of the year drops from 70 miles on the Pacific Coast to less than 45 miles in the Upper Midwest. These regional differences are large enough to affect adoption patterns and energy and environmental implications of BEVs relative to alternatives.
MPS Li-Ion Batteries Qualified to Fly on Canadian Sapphire Spacecraft
NASA Astrophysics Data System (ADS)
Remy, S.; Carre, A.; Kimber, R.; Alcindor, P.; Krabel, E.
2014-08-01
Saft Li-ion 8S3P MPS (Medium Prismatic cell for Space Battery) autonomous battery has been designed and qualified primarily to meet LEO power requirements. It has been available for more than 8 years, the original battery concept qualification program being successfully carried-out with CNES support in year 2005. This module has been selected for the first time by the UK satellite manufacturer SSTL for the Sapphire spacecraft platform, on behalf of the spacecraft prime MDA Systems Ltd (MDA) and customer the Canadian DND. Due to the high mechanical load demand in the specifications, a delta qualification campaign was launched to make sure that the MPS battery was able to cope with this requirement. A partner approach between Saft and SSTL led Saft to build some dedicated representative 5S packs, which have been step by step tested by SSTL shaker. Based on the results, the battery was made and finally installed inside the Sapphire spacecraft which was successfully launched on February 25th 2013 after battery storage of about 3.5 years.
Modeling the basal melting and marine ice accretion of the Amery Ice Shelf
NASA Astrophysics Data System (ADS)
Galton-Fenzi, B. K.; Hunter, J. R.; Coleman, R.; Marsland, S. J.; Warner, R. C.
2012-09-01
The basal mass balance of the Amery Ice Shelf (AIS) in East Antarctica is investigated using a numerical ocean model. The main improvements of this model over previous studies are the inclusion of frazil formation and dynamics, tides and the use of the latest estimate of the sub-ice-shelf cavity geometry. The model produces a net basal melt rate of 45.6 Gt year-1 (0.74 m ice year-1) which is in good agreement with reviewed observations. The melting at the base of the ice shelf is primarily due to interaction with High Salinity Shelf Water created from the surface sea-ice formation in winter. The temperature difference between the coldest waters created in the open ocean and the in situ freezing point of ocean water in contact with the deepest part of the AIS drives a melt rate that can exceed 30 m of ice year-1. The inclusion of frazil dynamics is shown to be important for both melting and marine ice accretion (refreezing). Frazil initially forms in the supercooled water layer adjacent to the base of the ice shelf. The net accretion of marine ice is 5.3 Gt year-1, comprised of 3.7 Gt year-1 of frazil accretion and 1.6 Gt year-1 of direct basal refreezing.
Merenstein, D J; Smith, K H; Scriven, M; Roberts, R F; Sanders, M E; Petterson, S
2010-07-01
Probiotic functional foods are widely advertised to consumers primarily based on probiotic supplements. Determine if consumption of yogurt containing a high dose of probiotics improves health in children ages 1-3 years attending daycare/school centers. Double-blinded, randomized, placebo-controlled, allocation concealment clinical trial. Outpatient participants in the Washington, DC area. 182 healthy children between the age of 1 and 3 years attending daycare/school at least 3 days a week. Active was a strawberry yogurt-based drink supplemented with Bifidobacterium animalis ssp. lactis (B. lactis) BB-12. The placebo was indistinguishable from the active drink, differing only in absence of the probiotic BB-12. Primary objective was to determine if consumption of a probiotic-containing yogurt-based drink decreases absences due to illnesses from daycare for children ages 1-3 years. Secondary was to determine if probiotic-containing yogurt-based drink improves overall parental satisfaction due to decreased absences from work and an overall healthier child. There were no significant differences in the days of missed school per group, with 51.9% in the active group and 47.1% in the placebo group missing at least 1 day of school throughout the study. Additionally, there were no differences in any secondary outcomes among the groups. Consumption of a yogurt-based drink delivering 10(10) CFU of Bifidobacterium animalis ssp. lactis (B. lactis) BB-12 per day did not decrease the number of days missed of school due to an illness. Additional independent research on the potential of BB-12 to reduce illness in children needs to be conducted.
Characteristics of retractions related to faked peer reviews: an overview.
Qi, Xingshun; Deng, Han; Guo, Xiaozhong
2017-08-01
A faked peer review is a novel cause for retraction. We reviewed the characteristics of papers retracted due to a faked peer review. All papers retracted due to faked peer reviews were identified by searching the Retraction Watch website and by conducting a manual search. All identified papers were confirmed in published journals. The information of retracted papers was collected, which primarily included publisher, journal, journal impact factor, country, as well as publication and retraction year. Overall, 250 retracted papers were identified. They were published in 48 journals by six publishers. The top 5 journals included the Journal of Vibration and Control (24.8%), Molecular Biology Reports (11.6%), Immunopharmacology and Immunotoxicology (8.0%), Tumour Biology (6.8%) and European Journal of Medical Research (6.4%). The publishers included SAGE (31%), Springer (26%), BioMed Central (18%), Elsevier (13%), Informa (11%) and LWW (1%). A minority (4%) of retracted papers were published in Science Citation Index (SCI) journals with an impact factor of >5. A majority (74.8%) of retracted papers were written by Chinese researchers. In terms of the publication year, the retracted papers were published since 2010, and the number of retracted papers peaked in 2014 (40.8%). In terms of the retraction year, the retractions started in 2012, and the number of retractions peaked in 2015 (59.6%). The number of papers retracted due to faked peer reviews differs largely among journals and countries. With the improvement of the peer review mechanism and increased education about publishing ethics, such academic misconduct may gradually disappear in future. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Changes in premiums of cancelled nongroup plans under the Affordable Care Act.
Maeda, Jared Lane L K; Chen, Jersey; Plemons, Brent R
2016-07-01
To examine the effect of the Affordable Care Act (ACA) on changes in premiums for subscribers of nongrandfathered, nongroup insurance plans that were "cancelled." Retrospective multivariate analyses. Changes in annual premiums post ACA were evaluated across subgroups of subscriber and health plan characteristics. Data was derived from databases containing information on premiums, plan benefit, and demographics for subscribers aged 18 to 64 years within Kaiser Permanente of the Mid-Atlantic States. A linear regression model was used to examine the independent association between subscriber and health plan characteristics on the relative change in premiums. In 2013, 4169 nongroup subscribers were enrolled in plans that were cancelled as a result of the ACA. The median pre-ACA premium was $3240 (range = $780-$39,492), which increased by a median of 21.3% (range = -77.4% to 193.6%), or $685 (range = -$27,464 to $8676), post ACA in 2014. Premiums increased more for high-deductible plans (median = 63.7%) than standard-deductible plans (median = 8.4%). Due to shifts in the age curve, premiums decreased for more than half of women aged 18 to 44 years, but increased by 35.2% for women aged 55 to 64 years. Premiums fell by 15.5% for subscribers who did not pass standard medical underwriting due to preexisting conditions. Changes in premiums in the nongroup market post ACA, varied substantially across subgroups, primarily due to differences in the amount of coverage, changes in rating criteria, shifts in the age curve, and anticipated differences in risk selection and composition of the risk pool. Given the extent of this variation, it would be incorrect to conclude the ACA as being uniformly beneficial or detrimental to subscribers of these cancelled plans.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hoffman, Matthew J.; Fountain, Andrew G.; Liston, Glen E.
Here, the McMurdo Dry Valleys of Antarctica host the coldest and driest ecosystem on Earth, which is acutely sensitive to the availability of water coming from glacial runoff. We modeled the spatial variability in ablation and assessed climate sensitivity of the glacier ablation zones using 16 years of meteorological and surface mass-balance observations collected in Taylor Valley. Sublimation was the primary form of mass loss over much of the ablation zones, except for near the termini where melt, primarily below the surface, dominated. Microclimates in ~10 m scale topographic basins generated melt rates up to ten times higher than overmore » smooth glacier surfaces. In contrast, the vertical terminal cliffs on the glaciers can have higher or lower melt rates than the horizontal surfaces due to differences in incoming solar radiation. The model systematically underpredicted ablation for the final 5 years studied, possibly due to an increase of windblown sediment. Surface mass-balance sensitivity to temperature was ~–0.02 m w.e. K –1, which is among the smallest magnitudes observed globally. We also identified a high sensitivity to ice albedo, with a decrease of 0.02 having similar effects as a 1 K increase in temperature, and a complex sensitivity to wind speed.« less
Hoffman, Matthew J.; Fountain, Andrew G.; Liston, Glen E.
2016-02-24
Here, the McMurdo Dry Valleys of Antarctica host the coldest and driest ecosystem on Earth, which is acutely sensitive to the availability of water coming from glacial runoff. We modeled the spatial variability in ablation and assessed climate sensitivity of the glacier ablation zones using 16 years of meteorological and surface mass-balance observations collected in Taylor Valley. Sublimation was the primary form of mass loss over much of the ablation zones, except for near the termini where melt, primarily below the surface, dominated. Microclimates in ~10 m scale topographic basins generated melt rates up to ten times higher than overmore » smooth glacier surfaces. In contrast, the vertical terminal cliffs on the glaciers can have higher or lower melt rates than the horizontal surfaces due to differences in incoming solar radiation. The model systematically underpredicted ablation for the final 5 years studied, possibly due to an increase of windblown sediment. Surface mass-balance sensitivity to temperature was ~–0.02 m w.e. K –1, which is among the smallest magnitudes observed globally. We also identified a high sensitivity to ice albedo, with a decrease of 0.02 having similar effects as a 1 K increase in temperature, and a complex sensitivity to wind speed.« less
Demographic history of an English coal-mining parish: Houghton-le-Spring, County Durham, 1660-1820
DOE Office of Scientific and Technical Information (OSTI.GOV)
Peck, T.R.
In 1666 the size of the population of Houghton-le-Spring was 2332. By 1821, the population had grown to 12,889 persons. The population of the village grew primarily due to increasing fertility during the period. The Total Martial Fertility Ratio (20-49) increased from 6.98 to 8.37 between the late seventeenth and the early nineteenth centuries. The mean age at first marriage for brides and grooms declined on average by three years. During the 160 years of the study the level of mortality actually increased. In the parish of Houghton-le-Spring, the coal miners, who were prime examples of proletarians, did marry muchmore » younger than a person engaged in the traditional occupations. Thus, the primary cause of the increasing level of fertility in the parish was the process of proletarianization. The study of mortality revealed that coal miners and their dependents suffered higher rates of mortality than persons in other occupations. These higher rates were partly caused by a greater incidence of deaths due to mining accidents. The population proved to be surprisingly immobile. Approximately 90% of the population lived their entire life within fifteen miles of their place of birth. This was true of all occupational groups.« less
Postural Tachycardia Syndrome (POTS)
Low, Phillip A.; Sandroni, Paola; Joyner, Michael; Shen, Win-Kuang
2014-01-01
Introduction POTS is defined as the development of orthostatic symptoms associated with a heart rate (HR) increment ≥30, usually to ≥120 bpm without orthostatic hypotension. Symptoms of orthostatic intolerance are those due to brain hypoperfusion and those due to sympathetic overaction. Methods We provide a review of POTS based primarily on work from the Mayo Clinic. Results Females predominate over males by 5:1. Mean age of onset in adults is about 30 years and most patients are between the ages of 20–40 years. Pathophysiologic mechanisms (not mutually exclusive) include peripheral denervation, hypovolemia, venous pooling, β-receptor supersensitivity, psychologic mechanisms, and presumed impairment of brain stem regulation. Prolonged deconditioning may also interact with these mechanisms to exacerbate symptoms. The evaluation of POTS requires a focused history and examination, followed by tests that should include HUT, some estimation of volume status and preferably some evaluation of peripheral denervation and hyperadrenergic state. All patients with POTS require a high salt diet, copious fluids, and postural training. Many require β-receptor antagonists in small doses and low-dose vasoconstrictors. Somatic hypervigilance and psychologic factors are involved in a significant proportion of patients. Conclusions POTS is heterogeneous in presentation and mechanisms. Major mechanisms are denervation, hypovolemia, deconditioning, and hyperadrenergic state. Most patients can benefit from a pathophysiologically based regimen of management. PMID:19207771
[The results of strontium-90 contact therapy to prevent the recurrence of pterygium].
Schultze, J; Hinrichs, M; Kimmig, B
1996-08-01
Aim of the study was the evaluation of the role of adjuvant radiation therapy in the prevention of recurrence after excision. Between July 1, 1985 and April 1, 1993, 64 patients (43 male, 21 female) were referred to radiation therapy after excision of a nasal pterygium. Radiation therapy was done with a strontium-90 eye applicator and a total dose of 30 Gy, fractionated in 6 fractions of 5 Gy each, 3 times a week. Forty-nine patients were treated primarily, 15 patients underwent radiation therapy for the first time in case of recurrent pterygium after multiple re-excisions. All patients had a following of 1 to 9 years with a median of 5.5 years. In 8 of 64 irradiated patients recurrent pterygium was detected (12.5%). Differentiated into the 2 groups 4 of the primarily treated patients had recurrent pterygium (8.16%), the other 4 were in the group with multiple former re-excisions (26.7%). With regard to the initiation of the irradiation after surgery pterygium did not recur in any of the primarily treated patients who were irradiated in between 3 days after surgery. In contrary 3 of 7 primarily treated patients (42.9%) who started radiation therapy between 7 and 10 days after surgery had recurrent pterygium. For the patients with primarily recurrent pterygium no dependence of the initiation of radiation therapy after surgery could be detected. Adjuvant radiation therapy after excision of pterygium lowers the rate of recurrence from about 40% to 12.5%, in a primarily adjuvant situation to 8.16%. In these patients radiation therapy should be initiated within 3 days after surgery. Patients with primarily recurrent pterygium have an elevated risk of recurrence independently of the initiation of radiation therapy.
Tinea corporis due to Trichophyton violaceum: A report of two cases.
Smriti, C; Anuradha, S; Kamlesh, T; Isampreet, K; Nitin, K
2015-01-01
Dermatophytes are Fungi which infect keratinized tissues, that is, skin epidermis, hair and nails. Trichophyton violaceum is an anthropophilic, cosmopolitan dermatophyte. It primarily causes tinea capitis and less commonly tinea corporis and tinea unguium. We present a report of two cases of tinea corporis due to T. violaceum in children. Infections due to T. violaceum are important because of its transmissibility within families and community and its potential to spread and establish in new geographical areas.
75 FR 54222 - Petition for Waiver of Compliance
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-03
... passenger car Tioga Pass is primarily equipped with double pane laminated safety glass, with the exception..., and no injuries have occurred to passengers or crew due to broken glass. Aronco additionally states...
Three-Dimensional Behavior of a Central Core Dam.
differences are primarily due to the effect of arching caused by the valley walls. A short discussion of stress conditions leading to conditions favorable to horizontal hydraulic fracturing is also given. (Author)
Melse, J M; Essink-Bot, M L; Kramers, P G; Hoeymans, N
2000-01-01
OBJECTIVES: This study estimated the burden of disease due to 48 major causes in the Netherlands in 1994 in disability-adjusted life-years (DALYs), using national epidemiologic data and disability weights, and explored associated problems and uncertainties. METHODS: We combined data from Dutch vital statistics, registrations, and surveys with Dutch disability weights to calculate disease-specific health loss in DALYs, which are the sum of years of life lost (YLLs) and years lived with disability (YLDs) weighted for severity. RESULTS: YLLs were primarily lost by cardiovascular diseases and cancers, while YLDs were mostly lost by mental disorders and a range of chronic somatic disorders (such as chronic nonspecific lung disease and diabetes). These 4 diagnostic groups caused approximately equal numbers of DALYs. Sensitivity analysis calls for improving the accuracy of the epidemiologic data in connection with disability weights, especially for mild and frequent diseases. CONCLUSIONS: The DALY approach appeared to be feasible at a national Western European level and produced interpretable results, comparable to results from the Global Burden of Disease Study for the Established Market Economies. Suggestions for improving the methodology and its applicability are presented. PMID:10937004
Long-term follow-up of cadaveric breast augmentation: what can we learn?
Modarressi, Ali; Villard, Jean; Tille, Jean-Christophe; Pittet, Brigitte
2015-05-01
Breast augmentation with cadaveric fat graft has long been available to patients in Eastern European countries, primarily in the Soviet Union and Eastern Germany. Most such procedures were performed from the 1970s to the 1990s. Although only a few case reports have been published, all of which involved complications that appeared several years after the procedure, it appears that, surprisingly, this nonvascularized and incompatible immunologic tissue is relatively well tolerated. We present the case of a 45-year-old Russian woman who underwent breast explantation, due to breast hardness and pain, 15 years after breast augmentation with cadaveric fat grafting. Through genetic studies, we confirmed that the host and the graft were HLA incompatible. Moreover, results of analyses excluded the possibility of an acute or chronic immunologic rejection by the host. We suppose that the early complications that often occur in such cases might result from a nonspecific, inflammatory reaction induced by acute tissue ischemia and necrosis, and the late local complications that occur years later may relate more to chronic inflammation, due to nonvascularized tissue, than to immunologic rejection. Therefore, we propose that different mechanisms may explain how this allogenic fat tissue could have been tolerated by the patient's immune system. We particularly underline the immunomodulatory effect of mesenchymal stem cells, which are abundant in adipose tissues. This characteristic of fat tissue should be investigated further to assess its potential in treating autoimmune diseases or reducing the likelihood of allograft rejections. © 2015 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.
NASA Astrophysics Data System (ADS)
Wagner, M.; Wang, M.; Miguez-Macho, G.; Miller, J. N.; Bagley, J. E.; Bernacchi, C.; Georgescu, M.
2016-12-01
Perennial bioenergy crops, such as switchgrass and miscanthus, have been posed as a more sustainable energy pathway relative to annual bioenergy crops due to their reduced carbon footprint and ability to grow on abandoned and degraded land, thereby, avoiding competition with food crops. Previous studies that replaced annual bioenergy crops with perennial crops noted regional cooling associated with enhanced ET due to their deeper rooting systems extracting deeper soil moisture. This study provides a more realistic assessment by (1) analyzing perennial bioenergy expansion only in suitable abandoned and degraded farmlands, and (2) using field scale measurements of albedo in conjunction with known vegetation fraction and leaf area index (LAI) values. High-resolution (2 km grid spacing) simulations were performed using a state-of-the-art atmospheric model (Weather Research and Forecasting system) dynamically coupled to a land surface model system over the Southern Plains of the U.S., during a normal precipitation year (2007) and a drought year (2011). Our results show that perennial bioenergy crop expansion leads to regional cooling (1-2 oC), that is driven primarily by enhanced reflection of shortwave radiation, and secondarily, by enhanced ET. Perennial bioenergy crop expansion was also shown to mitigate drought impacts through moistening and cooling of the near-surface environment. These impacts, however, were reduced during the drought year as a result of differential environmental conditions, when compared to those of the normal cimate year. This study serves as a major step towards assessing the sustainability of perennial bioenergy crop expansion under diverse hydrometeorological conditions by highlighting the driving mechanisms and processes associated with this energy pathway.
Risk factors for invasive reptile-associated salmonellosis in children.
Meyer Sauteur, Patrick M; Relly, Christa; Hug, Martina; Wittenbrink, Max M; Berger, Christoph
2013-06-01
Reptile-associated salmonellosis (RAS) in children has been reported primarily due to direct contact with turtles, but recently also due to indirect contact with more exotic reptiles, causing disease in infants. To evaluate risk factors for RAS, we reviewed the RAS cases published in the literature since 1965. A case was defined as a child ≤18 years of age with an epidemiological link by identification of Salmonella enterica in cultures from both the affected child and the exposed reptile. We identified a total of 177 otherwise healthy children (median age 1.0 years, range 2 days to 17.0 years). RAS manifested mainly with gastrointestinal disease, but 15% presented with invasive RAS, including septicemia, meningitis, and bone and joint infection. The children with invasive RAS were significantly younger than children with noninvasive disease (median age 0.17 and 2.0 years, p<0.0001). RAS is most frequently seen after exposure to turtles (42%). However, children with invasive RAS had been exposed more often (p≤0.001) to reptiles other than turtles, including iguanas, bearded dragons, snakes, chameleons, and geckos. Children exposed to those latter reptiles usually kept indoors were younger than children exposed to turtles mostly kept outdoors (p<0.0001). RAS in children is significantly associated with invasive disease at young age, in particular infants <6 months of age. Exposure to reptiles, other than turtles, kept indoors is associated with RAS at younger age and more invasive disease. This finding is helpful for recognizing or even preventing invasive RAS in young infants that are at highest risk.
Post-silking Factor Consequences for N Efficiency Changes Over 38 Years of Commercial Maize Hybrids.
Chen, Keru; Vyn, Tony J
2017-01-01
Hybrid selection in maize ( Zea mays L.) over the decades has increased post-silking dry matter (PostDM) and nitrogen (PostN) accumulation, often with an accompanying increase in one or more N use efficiency (NUE) metrics such as partial factor productivity (PFP), N conversion efficiency (NCE), and N internal efficiency (NIE). More certainty on the underlying mechanisms of how PostDM and PostN changes over time have contributed to NUE gains or losses in modern-era hybrids can only be realized by directly comparing hybrids of different eras in the context of production-system-relevant management systems. A two-year and two-location field study was conducted in Indiana with two N rates (55 and 220 kg N ha -1 ), three plant densities (54,000, 79,000, and 104,000 plants ha -1 ) and eight commercial hybrids that were released by a single seed company from 1967 to 2005. The main treatment effects of N rate, density, and hybrid dominated the PostDM and PostN responses, and there were no significant two-way or three-way interactions. Total dry matter at maturity gains averaged 80 kg ha -1 year -1 of hybrid release when averaged over locations, plant densities and N rates. Total N contents at maturity increased 0.68 kg ha -1 year -1 , primarily due to annual increases in grain N content (0.8 kg ha -1 year -1 ). Post-silking N uptake rate increased 0.44 kg ha -1 year -1 for these era hybrids in more favorable production site-years. Slopes of grain N concentration increases per unit PostN gain were similar for all hybrids. Gains in average PFP over time were considerably higher at the low N rate (0.9 kg ha -1 year -1 ) than at the high N rate (0.3 kg kg -1 year -1 ). Hybrid gains in NIE were evident from 1967 to 1994, but not thereafter. The low N rate and higher plant densities also increased relative NIE and NCE values, but without hybrid interactions. There was no consistent trend of NIE or NCE gains in these hybrids primarily because grain and whole-plant N concentrations didn't decline over the decades at either N rate, and because NIE and NCE were often plant-density dependent.
Lessons from 150 years of UK maternal hemorrhage deaths.
Kerr, Robert Stuart; Weeks, Andrew David
2015-06-01
We have reviewed maternal hemorrhage death rates in the UK over the past 150 years in order to draw lessons from this material for current attempts to reduce global maternal mortality. Mortality rates from data in the UK Annual Reports from the Registrar General were entered into a database. Charts were created to display trends in hemorrhage mortality, allowing comparison with historical medical advances. Hemorrhage death rates fell steadily before the 1930s; between 1874 and 1926 they fell by 56%. In contrast, there was no consistent reduction in overall maternal mortality rates until the 1930s; from 1932 to 1952 they fell by 85%, primarily due to a reduction in sepsis deaths. In conclusion the majority of maternal hemorrhage mortality reductions in the UK occurred prior to the availability of effective oxytocics, antibiotics, and blood transfusion. Improving access to and standards of maternal care is key to addressing global maternal mortality today. © 2015 Nordic Federation of Societies of Obstetrics and Gynecology.
How Do They Do It? The Immigrant Paradox in the Transition to Adulthood
Moon, Ui Jeong
2016-01-01
How do children of immigrants consistently outperform children of native-born U.S. parents, in spite of lower familial resources? Using the Transition to Adulthood Study of the Panel Study of Income Dynamics, children of immigrant and native-born parents completing high school in 2005–13 are followed they move into the young adult years. Children of immigrants are more likely to enroll in college, be employed or in school, and less likely to have a criminal record as young adults or to have a child than children of nonimmigrants. This is not a result of immigrant parentage but due primarily to greater parental educational expectations; immigrants enjoy a differential return to parental expectations for boys’ college enrollment as well. Reading skills and activity patterns in the secondary school years also contribute to better outcomes. Children of immigrants are better able to translate their reading comprehension skills to college or employment later on. PMID:26973039
NASA Technical Reports Server (NTRS)
Miller, James R.; Russell, Gary L.
1996-01-01
The annual flux of freshwater into the Arctic Ocean by the atmosphere and rivers is balanced by the export of sea ice and oceanic freshwater. Two 150-year simulations of a global climate model are used to examine how this balance might change if atmospheric greenhouse gases (GHGs) increase. Relative to the control, the last 50-year period of the GHG experiment indicates that the total inflow of water from the atmosphere and rivers increases by 10% primarily due to an increase in river discharge, the annual sea-ice export decreases by about half, the oceanic liquid water export increases, salinity decreases, sea-ice cover decreases, and the total mass and sea-surface height of the Arctic Ocean increase. The closed, compact, and multi-phased nature of the hydrologic cycle in the Arctic Ocean makes it an ideal test of water budgets that could be included in model intercomparisons.
Ren, Feiyue; Reilly, Kim; Kerry, Joseph P; Gaffney, Michael; Hossain, Mohammad; Rai, Dilip K
2017-06-28
We carried out a 6-year study to assess the effect of conventional, organic, and mixed cultivation practices on bioactive compounds (flavonoids, anthocyanins) and antioxidant capacity in onion. Total flavonoids, total anthocyanins, individual flavonols, individual anthocyanins, and antioxidant activity were measured in two varieties ('Hyskin' and 'Red Baron') grown in a long-term split-plot factorial systems comparison trial. This is the first report of repeated measurements of bioactive content over an extensive time period in a single crop type within the same trial. Antioxidant activity (DPPH and FRAP), total flavonol content, and levels of Q 3,4' D and Q 3 G were higher in both varieties under fully organic compared to fully conventional management. Total flavonoids were higher in 'Red Baron' and when onions were grown under organic soil treatment. Differences were primarily due to different soil management practices used in organic agriculture rather than pesticide/ herbicide application.
Mycosis fungoides of the true vocal cord: a case report and review of the literature.
Maleki, Zahra; Azmi, Farrukh
2010-09-01
Mycosis fungoides is the most common type of cutaneous malignant T cell lymphoma which primarily affects skin. However, extracutaneous manifestation may occur in advanced stages, mostly observed in postmortem studies. We present a case of mycosis fungoides that disseminated to the true vocal cord of a 48-year-old African American man who presented with hoarseness. Only two cases that have also demonstrated a rare involvement of the true vocal cord have been reported in the English literature. In both cases, mycosis fungoides infiltration of the true vocal cord was seen postmortem, along with visceral dissemination of mycosis fungoides. We herein describe a single extracutaneous manifestation of mycosis fungoides in the true vocal cord of a living patient with a 21-year diagnosis of mycosis fungoides. Vocal cord involvement by mycosis fungoides must be considered as one of the differential diagnoses in any mycosis fungoides patients who complain of persistent hoarseness. Awareness of this entity is clinically important due to the necessity of a different management.
Liu, Yu; Wang, Yi-Feng
2017-07-01
We report a case of successful vaginal delivery after vaginal reconstruction with labium minus flaps in a 23-year-old patient with congenital vaginal atresia. The patient primarily presented with amenorrhea and cyclic abdominal pain; transabdominal ultrasonography revealed an enlarged uterus due to hematometra and absence of the lower segment of the vagina. Eight years ago, she had undergone an unsuccessful attempt at canalization at a local hospital. Upon referral to our hospital, she underwent vaginal reconstruction with labium minus flaps. Four months after this procedure, she became pregnant and, subsequently, successfully and safely vaginally delivered a healthy female baby weighing 3250 g at 38 +1 weeks' gestation. The delivery did not involve perineal laceration by lateral episiotomy. To the best of our knowledge, this is the first reported case of successful vaginal delivery at term after vaginal reconstruction with labium minus flaps in a patient with vaginal atresia. © 2017 Japan Society of Obstetrics and Gynecology.
Visual Acuity Improvement of Amblyopia in an Adult With Levodopa/Carbidopa Treatment.
Orge, Faruk H; Dar, Suhail A
2015-09-09
Amblyopia is the leading cause of visual loss in children, affecting 2% to 3% of the population. Occlusion of the dominant eye is the primary and best treatment, although efficacy decreases after 6 years of age. As a result, levodopa/carbidopa has been explored as an adjunct to conventional therapy and has been shown to have an immediate impact on visual acuity. Several studies to date have shown mixed results on the benefit of supplementing occlusion therapy with levodopa/carbidopa, although they have primarily studied children. The authors describe the oldest patient (46 years old) documented in the literature to have shown improvement in visual acuity using levodopa/carbidopa. He was given a 16-week course at a dose in line with previous studies while being effectively occluded full time due to a glaucomatous right eye with no light perception. On 3-month follow-up, his left eye improved two lines and stabilized at 6 months. Copyright 2015, SLACK Incorporated.
Harlaar, Nicole; Deater-Deckard, Kirby; Thompson, Lee A.; DeThorne, Laura S.; Petrill, Stephen A.
2013-01-01
This study used a cross-lagged twin design to examine reading achievement and independent reading from 10 to 11 years (n = 436 twin pairs). Reading achievement at age 10 significantly predicted independent reading at age 11. The alternative path, from independent reading at age 10 to reading achievement at age 11, was not significant. Individual differences in reading achievement and independent reading at both ages were primarily due to genetic influences. Furthermore, individual differences in independent reading at age 11 partly reflected genetic influences on reading achievement at age 10. These findings suggest that genetic influences that contribute to individual differences in children’s reading abilities also influence the extent to which children actively seek out and create opportunities to read. PMID:22026450
Symptomatic Spinal Epidural Lipomatosis After a Single Local Epidural Steroid Injection
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tok, Chung Hong, E-mail: rogertok@gmail.com; Kaur, Shaleen; Gangi, Afshin
Spinal epidural lipomatosis is a rare disorder that can manifest with progressive neurological deficits. It is characterized by abnormal accumulation of unencapsulated epidural fat commonly associated with the administration of exogenous steroids associated with a variety of systemic diseases, endocrinopathies, and Cushing syndrome (Fogel et al. Spine J 5:202-211, 2005). Occasionally, spinal epidural lipomatosis may occur in patients not exposed to steroids or in patients with endocrinopathies, primarily in obese individuals (Fogel et al. Spine J 5:202-211, 2005). However, spinal lumbar epidural lipomatosis resulting from local steroid injection has rarely been reported. We report the case of a 45-year-old diabeticmore » man with claudication that was probably due to symptomatic lumbar spinal lipomatosis resulting from a single local epidural steroid injection.« less
Super Resolution Imaging of the Bottomside Ionosphere with the LWA
NASA Astrophysics Data System (ADS)
Obenberger, K.; Parris, R. T.; Taylor, G. B.; Dowell, J.; Malins, J. B.; Pedersen, T.
2017-12-01
Standard ionospheric sounding instruments typically only utilize a handful HF antennas to receive their transmitted signal, and therefore are limited in their ability to image reflections from the bottomside ionosphere. This limitation is primarily due to the low signal to noise ratio of only a few receiving elements. However, recent advancements in digital processing have ushered in a new era of many-element radio telescopes, capable of sub degree all-sky imaging in the HF band. The Long Wavelength Array station at Sevilleta National Wildlife Refuge, New Mexico (LWA-SV), which was specifically designed with improved HF performance for imaging bottomside propagation, began observations this year. I will discuss the new capabilities and imaging techniques of LWA-SV, and show some preliminary measurements of small scale ionospheric structure.
Metagenomics uncovers gaps in amplicon-based detection of microbial diversity
Eloe-Fadrosh, Emiley A.; Ivanova, Natalia N.; Woyke, Tanja; ...
2016-02-01
Our view of microbial diversity has expanded greatly over the past 40 years, primarily through the wide application of PCR-based surveys of the small-subunit ribosomal RNA (SSU rRNA) gene. Yet significant gaps in knowledge remain due to well-recognized limitations of this method. Here in this paper, we systematically survey primer fidelity in SSU rRNA gene sequences recovered from over 6,000 assembled metagenomes sampled globally. Our findings show that approximately 10% of environmental microbial sequences might be missed from classical PCR-based SSU rRNA gene surveys, mostly members of the Candidate Phyla Radiation (CPR) and as yet uncharacterized Archaea. In conclusion, thesemore » results underscore the extent of uncharacterized microbial diversity and provide fruitful avenues for describing additional phylogenetic lineages.« less
Khan, Sana; Waqar Elahi, Muhammad; Ullah, Waqas; Ahmad, Ejaz; Al Mohajer, Mayar; Majeed, Aneela
2017-01-01
Mucor and Rhizopus cause life-threatening infections primarily involving the lungs and sinuses, which disseminate very rapidly by necrosis and infarction of the contiguous tissues. We present a case of a 64-year-old African American posttransplant patient who presented with a productive cough and weight loss. He had a past surgical history of renal transplant for renal cell carcinoma and was on dual immunosuppressive therapy, that is, mycophenolate and tacrolimus. During his hospital stay, he developed a pneumopericardium due to the direct extension of a lung lesion. The diagnosis was made by radiological imaging and PCR result which was consistent with Mucor species. He was treated with antifungal therapy. The purpose of this report is to highlight the unusual association of mucormycosis with pneumopericardium. PMID:28596926
Ahmed, Farhan; El-Kadiki, Alia; Gibbons, Stephen
2017-06-01
Dysbetalipoproteinemia is often associated with apolipoprotein E2E2 homozygosity; however, lipoprotein electrophoresis may also be used to assist in the diagnosis. The aim of this study was to compare apolipoprotein E (apo E) genotyping and lipoprotein electrophoresis in investigating dysbetalipoproteinemia. Data were collected over a three-year period from a lipid clinic in a tertiary referral centre and reviewed for apo E genotyping and lipoprotein electrophoresis. Sixty-two patients had both apo E genotyping and lipoprotein electrophoresis. Of these, 16 patients showed broad beta band on electrophoresis. However, only 3 of them had apo E2E2 homozygosity on genotyping. Lipoprotein electrophoresis and apo E genotyping results showed poor concordance. This was primarily due to visual interpretation error of lipoprotein electrophoresis which may over diagnose dysbetalipoproteinemia.
Satisfactory results at 8 years mean follow-up after ADVANCE® medial-pivot total knee arthroplasty.
Chinzei, Nobuaki; Ishida, Kazunari; Tsumura, Nobuhiro; Matsumoto, Tomoyuki; Kitagawa, Atsushi; Iguchi, Tetsuhiro; Nishida, Kotaro; Akisue, Toshihiro; Kuroda, Ryosuke; Kurosaka, Masahiro
2014-03-01
Although good overall results have been reported with TKA, certain problems and limitations remain, primarily due to postoperative differences in joint kinematics, when compared with the normal knee. ADVANCE® Medial-Pivot TKA involves replicating the medial pivoting behavior observed in normal knees. Here, we aimed to investigate the clinical and radiological results and complications of TKA using this implant, at mid-term follow-up. From January 2001 to March 2012, we retrospectively selected 76 patients (85 knees; mean age at operation, 70.2±8.1 years; range, 51-88 years) with a mean follow-up period of 93.1±14.3 months (range, 72-132 months). Indications for TKA included primary degenerative osteoarthritis (60 knees), rheumatoid arthritis (22 knees), osteonecrosis (two knees), and osteoarthritis following high tibial osteotomy (one knee). The clinical and radiographic results were evaluated. Kaplan-Meier survivorship analysis indicated a success rate of 98.3% (95% confidence interval, 96.6-99.9%). Comparison of pre- and postoperative knee extension angles and ranges of motion showed significant improvement postoperatively, in both the Knee Society Scores (KSS) and Knee Society Functional Scores (KSFS) (p<0.05). In one case, radiographic assessment indicated implant loosening due to infection; however, despite this complication, significant improvement of postoperative varus or valgus deformity angles were noted in all cases (p<0.05). Patients undergoing ADVANCE® Medial-Pivot TKA achieved excellent clinical and radiographic results without any implant-related failures at mid-term follow-up. Level IV. © 2013.
Summer distributions of forage fish in the eastern Bering Sea
NASA Astrophysics Data System (ADS)
Parker-Stetter, Sandra L.; Horne, John K.; Farley, Edward V.; Barbee, David H.; Andrews, Alexander G.; Eisner, Lisa B.; Nomura, Jennifer M.
2013-10-01
Juvenile and small adult fish, typically called forage fish, are an important but poorly studied part of the eastern Bering Sea (EBS) ecosystem. Acoustic and trawl data from a non-target survey were used to evaluate distributions of capelin (Mallotus villosus), age-0 Pacific cod (Gadus macrocephalus), and age-0 walleye pollock (Theragra chalcogramma, herein pollock) in 2006-2010. Within the surface zone (15 m to ~35 m, evaluated 2006-2010), capelin occurred throughout the EBS but primarily in the middle shelf. Capelin were also present in the midwater zone (~35 m to 0.5 m off-bottom) in both 2009 and 2010 (evaluated 2009-2010), and resulted in water column zone (15 m to 0.5 m off-bottom) distributions that differed from surface zone characterizations. Age-0 Pacific cod occurred primarily in the surface zone of the middle and outer shelf regions in all years. As midwater and surface zone age-0 Pacific cod were often coincident, water column zone distributions in 2009-2010 were similar to surface zone distributions. Age-0 pollock were found in the EBS surface zone in all years, primarily in the middle and outer shelf regions. High densities of age-0 pollock occurred in the midwater zone in 2006-2007 and 2009-2010. Water column zone distributions of age-0 pollock were similar to surface zone distributions in 2006-2007, but differed in 2009-2010 due to low numbers of age-0 pollock in the surface zone and presence of high densities in the midwater zone of the outer shelf region. While general patterns in capelin distribution in the surface zone were similar between the present and the previous studies, the acoustic-trawl characterization suggested that capelin densities were high in the middle shelf region. As expected, surface zone distributions of age-0 Pacific cod and age-0 pollock were similar to previous characterizations. Observed high densities of midwater age-0 pollock have not been described by previous studies. Annual abundance indices based on bottom or surface trawl data alone will not be sufficient in all years. Data and conclusions from non-target surveys may be constrained compared to dedicated survey efforts, but can provide baseline distributions, potential abundance indices, and insight for planning future research.
Iron deficiency--facts and fallacies.
Oski, F A
1985-04-01
Iron deficiency occurs in all strata of society, is primarily a result of postnatal feeding practices and not due to congenital deficiencies of iron, can be prevented by appropriate dietary guidance, and, when present, produces important nonhematologic manifestations.
Wessman, Laurel L; Andersen, Louise K; Davis, Mark D P
2018-01-29
Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature. Using the Rochester Epidemiology Project, population-based epidemiologic studies have been performed to estimate the incidence of specific skin diseases over the past 50 years. In older persons (>65 years), nonmelanoma skin cancer, lentigo maligna, herpes zoster, delusional infestation, venous stasis syndrome, venous ulcer, and burning mouth syndrome were more commonly diagnosed. In those younger than 65 years, atypical nevi, psoriatic arthritis, pityriasis rosea, herpes progenitalis, genital warts, alopecia areata, hidradenitis suppurativa, infantile hemangioma, Behçet's disease, and sarcoidosis (isolated cutaneous, with sarcoidosis-specific cutaneous lesions and with erythema nodosum) had a higher incidence. Many of the incidence rates by age group of diseases primarily affecting the skin derived from the Rochester Epidemiology Project were similar to those reported elsewhere. © 2018 The International Society of Dermatology.
Life history of a large flake biface
NASA Astrophysics Data System (ADS)
Baena Preysler, Javier; Torres Navas, Concepción; Sharon, Gonen
2018-06-01
Bifaces, primarily handaxes and cleavers, are the hallmark of the Acheulian techno-complex lithic industry. They spread across Africa and Eurasia during the Early to Middle Pleistocene. While many attempts have been made to define and describe the typology and technology of these tools, most focus on a single stage in their manufacture and usage, from quarry to discard. These attempts are fragmented, primarily due to the fact that at no single site are all stages of biface manufacture and use represented. An additional factor that appears to impede attempts to present the full "life cycle" of bifaces is the view of all Acheulian assemblages as belonging to a single cultural entity. While all assemblages belong to the same techno-complex, distinct stages and phases should be recognized, each different in typology, technology, and probably also in chronology. This research focuses on the large flake stage of the Acheulian. Data accumulated over many years of research from different regions are analyzed together in an attempt to present a holistic view of the life cycle of a biface. The study of particular Acheulian sites from the Levant and Western Europe enables us to reconstruct all stages of the biface, from raw material exploitation to final discard. The result is a model more comprehensive and precise than those suggested previously for understanding the Large Flake Acheulian.
Calculus Students' Representation Use in Group-Work and Individual Settings
ERIC Educational Resources Information Center
Zazkis, Dov
2013-01-01
The study of student representation use and specifically the distinction between analytic and visual representations has fueled a long line of mathematics education literature that began more than 35 years ago. This literature can be partitioned into two bodies of work, one that is primarily cognitive and one that is primarily social. In spite of…
Code of Federal Regulations, 2011 CFR
2011-01-01
... Product Safety Improvement Act provides for specific lead limits in children's products. Section 101(a) of the CPSIA provides that by February 10, 2009, products designed or intended primarily for children 12... designed or intended primarily for children 12 years of age or younger cannot contain more than 300 ppm of...
Peiso, Onneile O.; Bronsvoort, Barend M. de C.; Handel, Ian G.; Volkova, Victoriya V.
2011-01-01
Background Incursions of contagious diseases of livestock into disease-free zones are inevitable as long as the diseases persist elsewhere in the world. Knowledge of where, when and how incursions have occurred helps assess the risks, and regionalize preventative and reactive measures. Methodology Based on reports of British governmental veterinary services, we review occurrence of the former OIE List A diseases, and of Aujeszky's disease, anthrax and bovine tuberculosis (bTB) in farm-animals in Great Britain (GB) between 1938 and 2007. We estimate incidence of each disease on GB agricultural holdings and fraction of susceptible farm-animals culled to control the disease each year. We then consider the frequency and incidence of the diseases in Scotland alone. The limitations of available data on historical disease occurrence and denominator populations are detailed in Text S2. Conclusions The numbers of livestock and poultry farmed in GB grew over the years 1938–2007; the number of agricultural holdings decreased. An amalgamation of production on larger holdings took place from the 1940s to the 1980s. The maximum annual incidence of a reviewed disease in GB 1938–2007 was reported for bTB, 1.69% of holdings in 1961. This was followed by Newcastle disease, 1.50% of holdings in 1971, and classical swine fever, 1.09% of holdings in 1940. The largest fractional cull of susceptible livestock in a single year in each of the four decades 1950s–1980s was due to a viral disease primarily affecting swine. During the periods 1938–1949 and 2000–2007 this was due to outbreaks of foot and mouth disease. In the absence of incursions of the former OIE List A diseases in the 1990s, this was due to bTB. Over the 70 years, the diseases were reported with lower frequency and lower annual incidence in Scotland, as compared to when these statistics are considered for GB as a whole. PMID:21818292
Population structure and genetic diversity in North American Hedysarum boreale Nutt.
Bradley S. Bushman; Steven R. Larson; Michael D. Peel; Michael E. Pfrender
2007-01-01
Hedysarum boreale Nutt. is a perennial legume native to western North America, with robust foliage in the late spring season. Due to its wide native range, forage value, and N2 fixation, H. boreale is of interest for rangeland revegetation and production. Seed cost is a major obstacle for utilization of H. boreale, primarily due to seed shattering and unreliable seed...
Responses of skeletal muscle to unloading, a review
NASA Technical Reports Server (NTRS)
Tischler, M. E.; Jaspers, S. R.; Henriksen, E. J.; Jacob, S.
1985-01-01
Suspension models were used to study muscle response to reduced activity. During 6 days of tail casting, the soleus (SOL) atrophies while the extensor digitorum longus grows relatively normally. After discounting those changes in both muscles due primarily to increased secretion of adrenal hormones, the following conclusions regarding the specific responses of the SOL could be drawn: (1) Atrophy is probably due primarily to increased protein degradation; (2) Decreased synthesis of glutamine may result from reduced availability of ammonia due to diminished use of ATP; (3) Greater muscle glycogen seems to reflect an increased response to insulin of glucose uptake which leads to greater glucose metabolism; and (4) Faster catabolism of branched-chain amino acids can be attributed to enhanced flux through ketoacid dehydrogenase. Studies by others using tail casted suspended rats showed in the SOL: (1) a gradual switch from type 1 to type 2 fibers; (2) increased acid protease activity; and (3) altered muscle function and contractile duration. Using harness suspended rats, others showed in the SOL: (1) significant atrophy; (2) increased numbers of glucocorticoid receptors; and (3) no change in muscle fatigability.
Responses of skeletal muscle to unloading - A review
NASA Technical Reports Server (NTRS)
Tischler, M. E.; Jaspers, S. R.; Henriksen, E. J.; Jacob, S.
1985-01-01
Suspension models were used to study muscle response to reduced activity. During 6 days of tail casting, the soleus (SOL) atrophies while the extensor digitorum longus grows relatively normally. After discounting those changes in both muscles due primarily to increased secretion of adrenal hormones, the following conclusions regarding the specific responses of the SOL could be drawn: (1) Atrophy is probably due primarily to increased protein degradation; (2) Decreased synthesis of glutamine may result from reduced availability of ammonia due to diminished use of ATP; (3) Greater muscle glycogen seems to reflect an increased response to insulin of glucose uptake which leads to greater glucose metabolism; and (4) Faster catabolism of branched-chain amino acids can be attributed to enhanced flux through ketoacid dehydrogenase. Studies by others using tail casted suspended rats showed in the SOL: (1) a gradual switch from type 1 to type 2 fibers; (2) increased acid protease activity; and (3) altered muscle function and contractile duration. Using harness suspended rats, others showed in the SOL: (1) significant atrophy; (2) increased numbers of glucocorticoid receptors; and (3) no change in muscle fatigability.
Suppression of ASR through aggregate coating.
DOT National Transportation Integrated Search
2013-08-01
Many highways, runways, parking lots and bridges are suffering from premature deterioration due to : alkali silica reaction (ASR) that takes place between the alkalis contributed primarily by the cement and : a reactive form of silica from specific s...
Iowa pavement asset management decision-making framework.
DOT National Transportation Integrated Search
2015-10-01
Most local agencies in Iowa currently make their pavement treatment decisions based on their limited experience due primarily to : lack of a systematic decision-making framework and a decision-aid tool. The lack of objective condition assessment data...
Improvements to video imaging detection for dilemma zone protection.
DOT National Transportation Integrated Search
2009-02-01
The use of video imaging vehicle detection systems (VIVDS) at signalized intersections in Texas has : increased significantly due primarily to safety issues and costs. Installing non-intrusive detectors at : intersections is almost always safer than ...
Field study of an integral backwall bridge : final report.
DOT National Transportation Integrated Search
1996-01-01
Integral bridges offer reduced maintenance expenditures, primarily due to the elimination of deck expansion joints. The design of an integral bridge, however, is complicated by the soil-structure interaction associated with thermal movements. It has ...
State of Practice for Emerging Waste Conversion Technologies
New technologies to convert municipal and other waste streams into fuels and chemical commodities, termed conversion technologies, are rapidly developing. Conversion technologies are garnering increasing interest and demand due primarily to alternative energy initiatives. These t...
NASA Astrophysics Data System (ADS)
Hawtree, D.; Nunes, J. P.; Keizer, J. J.; Jacinto, R.; Santos, J.; Rial-Rivas, M. E.; Boulet, A.-K.; Tavares-Wahren, F.; Feger, K.-H.
2015-07-01
The north-central region of Portugal has undergone significant land cover change since the early 1900s, with large-scale replacement of natural vegetation types with plantation forests. This transition consisted of an initial conversion primarily to Pinus pinaster, followed by a secondary transition to Eucalyptus globulus. This land cover change is likely to have altered the hydrologic functioning of this region; however, these potential impacts are not fully understood. To contribute to a better understanding of the potential hydrologic impacts of this land cover change, this study examines the temporal trends in 75 years of data from the Águeda watershed (part of the Vouga Basin) over the period of 1936-2010. A number of hydrometeorological variables were analyzed using a combined Thiel-Sen/Mann-Kendall trend-testing approach, to assess the magnitude and significance of patterns in the observed data. These trend tests indicated that there have been no significant reductions in streamflow over either the entire test period, or during sub-record periods, despite the large-scale afforestation which has occurred. This lack of change in streamflow is attributed to the specific characteristics of the watershed and land cover change. By contrast, a number of significant trends were found for baseflow index, with positive trends in the early data record (primarily during Pinus pinaster afforestation), followed by negative trends later in the data record (primarily during Eucalyptus globulus afforestation). These trends are attributed to land use and vegetation impacts on streamflow generating processes, both due to species differences and to alterations in soil properties (i.e., infiltration capacity, soil water repellency). These results highlight the importance of considering both vegetation types/dynamics and watershed characteristic when assessing hydrologic impacts, in particular with respect to soil properties.
How Many Kinds of Birds Are There and Why Does It Matter?
Barrowclough, George F; Cracraft, Joel; Klicka, John; Zink, Robert M
2016-01-01
Estimates of global species diversity have varied widely, primarily based on variation in the numbers derived from different inventory methods of arthropods and other small invertebrates. Within vertebrates, current diversity metrics for fishes, amphibians, and reptiles are known to be poor estimators, whereas those for birds and mammals are often assumed to be relatively well established. We show that avian evolutionary diversity is significantly underestimated due to a taxonomic tradition not found in most other taxonomic groups. Using a sample of 200 species taken from a list of 9159 biological species determined primarily by morphological criteria, we applied a diagnostic, evolutionary species concept to a morphological and distributional data set that resulted in an estimate of 18,043 species of birds worldwide, with a 95% confidence interval of 15,845 to 20,470. In a second, independent analysis, we examined intraspecific genetic data from 437 traditional avian species, finding an average of 2.4 evolutionary units per species, which can be considered proxies for phylogenetic species. Comparing recent lists of species to that used in this study (based primarily on morphology) revealed that taxonomic changes in the past 25 years have led to an increase of only 9%, well below what our results predict. Therefore, our molecular and morphological results suggest that the current taxonomy of birds understimates avian species diversity by at least a factor of two. We suggest that a revised taxonomy that better captures avian species diversity will enhance the quantification and analysis of global patterns of diversity and distribution, as well as provide a more appropriate framework for understanding the evolutionary history of birds.
Foraminifera Record the Good Years More than the Bad
NASA Astrophysics Data System (ADS)
Hull, P. M.
2014-12-01
Past ocean conditions are primarily discerned from geochemical and community-based analyses of fossilized taxa, each of which have unique environmental niches and dynamics. A key requirement of such paleoceanographic studies is that some unbiased or well-constrained record of the living ecosystem and climate is deposited on the sea floor and preserved through the post-depositional processes that act to distort them. It is widely known that foraminiferal species exhibit varying seasonal preferences and that seasonality is a key variable to account for in paleoceanographic reconstructions. However, on longer time scales (> year), it is generally assumed that species record the 'average' environmental conditions or typical variance (e.g., El Nino intensity) that existed in a given, time-averaged sediment sample. Here I examine planktonic foraminiferal population dynamics on yearly and longer time scales, in order to quantify their effect on paleoceanographic reconstructions. Using a previously published record of >250 years of population dynamics in the Santa Barbara Basin sediments, I find that the majority of individuals in a given species lived during a small subset of the total years (~15- 37% of years depending on the species). Populations of shallow, mixed layer species primarily represent the warmest, youngest years, while thermocline species primarily represent the cooler, older years. Importantly, the seasonality of species does not always predict their interannual dynamics. The general importance of long time-scale population dynamics on paleoceanographic reconstructions will also be considered in a theoretical model parameterized with temporally explicit species co-variances and temperature variability. Such modeling is needed to constrain the relative impact that a very good year can have on our interpretation of the 'average' of hundreds to thousands of years.
Bobowski, Nuala
2015-01-01
Dietary salt reduction of Americans has been a focus of public health initiatives for more than 40 years primarily due to the association between high salt intake and development of hypertension. Despite past efforts, salt intake of Americans has remained at levels well above dietary recommendations, likely due in part to the hedonic appeal of salty taste. As such, in 2010 the Institute of Medicine suggested a strategy of gradual salt reduction of processed foods, the primary source of Americans’ dietary salt intake, via an approach intended to minimize impact on consumer acceptability of lower-sodium foods. This brief review discusses the ontogeny and development of human salt taste preference, the role of experience in shifting salt preference, and sources of dietary salt. Our current understanding of shifting human salt taste preference is discussed within the context of potential opportunities for success in reducing dietary salt, and gaps in the research that both limit our ability to predict effectiveness of gradual salt reduction and that need be addressed before a strategy to shift salt preference can realistically be implemented. PMID:26451233
Racial Convergence in Cigarette Use from Adolescence to the Mid-Thirties*
PAMPEL, FRED C.
2011-01-01
Cigarette smoking by whites and African Americans shows puzzling age differences: An African American advantage during the teen years no longer appears in mid-adulthood. This study uses two data sets to examine whether the life-course change is real–and not due to misleading comparisons across different cohorts–and then whether the racial convergence is consistent with resource or stress arguments emphasizing, respectively, cessation among whites or late initiation among African Americans. First, multilevel growth models using data from the National Youth Survey–a prospective, longitudinal study of a randomly selected national sample of teens followed from ages 12 to 18 in 1977 to ages 26 to 34 in 1992–reveal that the racial convergence in smoking prevalence over the life course among this cohort is due primarily to greater white cessation. Second, consecutive cross-sectional samples of the National Health Survey replicate the broad patterns found in the NYS and show that convergence in smoking trajectories by race has strengthened over time. Together, the results most favor a resource explanation of the different life-course patterns of smoking among whites and African Americans. PMID:19181051
Liu, Yinzhan; Reich, Peter B; Li, Guoyong; Sun, Shucun
2011-06-01
Phenological mismatches due to climate change may have important ecological consequences. In a three-year study, phenological shifts due to experimental warming markedly altered trophic relationships between plants and insect herbivores, causing a dramatic decline of reproductive capacity for one of the plant species. In a Tibetan meadow, the gentian (Gentiana formosa) typically flowers after the peak larva density of a noctuid moth (Melanchra pisi) that primarily feeds on a dominant forb (anemone, Anemone trullifolia var. linearis). However, artificial warming of approximately 1.5 degrees C advanced gentian flower phenology and anemone vegetative phenology by a week, but delayed moth larvae emergence by two weeks. The warming increased larval density 10-fold, but decreased anemone density by 30%. The phenological and density shifts under warmed conditions resulted in the insect larvae feeding substantially on the gentian flowers and ovules; there was approximately 100-fold more damage in warmed than in unwarmed chambers. This radically increased trophic connection reduced gentian plant reproduction and likely contributed to its reduced abundance in the warmed chambers.
ERIC Educational Resources Information Center
Enyeart, Christine; Diehl, Juliet; Hampden-Thompson, Gillian; Scotchmer, Marion
2006-01-01
This Issue Brief describes school-to-home communication practices and opportunities for parent involvement at school as reported by parents of U.S. school-age students from primarily English-and primarily Spanish-speaking households during the 2002-03 school year. Data are drawn from the Parent and Family Involvement in Education Survey of the…
ERIC Educational Resources Information Center
Boseovski, Janet J.; Shallwani, Sadaf; Lee, Kang
2009-01-01
The present study examined children's use of behavioural outcome information to make personality attributions in social and non-social contexts. One hundred and twenty-eight 3- to 6-year-olds were told about a story actor who engaged in primarily successful or primarily unsuccessful interactions with several different people (social context) or…
deBruyn, Jennifer C; Jacobson, Kevan; El-Matary, Wael; Carroll, Matthew; Wine, Eytan; Wrobel, Iwona; Van Woudenberg, Mariel; Huynh, Hien Q
2018-02-01
Data on long-term real-world outcomes of infliximab in pediatric Crohn disease are limited. The aim of the study was to evaluate infliximab optimization and durability in children with Crohn disease. We performed a retrospective review of children with Crohn disease who started infliximab from January 2008 to December 2012 in 4 Canadian tertiary care centers. A priori factors associated with optimization and discontinuation from loss of response were evaluated using logistic regression and Cox proportional hazards model, respectively. One hundred eighty children (54.4% boys) started infliximab; all completed induction. Median age at infliximab start was 14.3 years (Q1, Q3: 12.8, 15.9 years) and median time from diagnosis to infliximab start was 1.5 years (Q1, Q3: 0.6, 3.5 years). At last follow-up, 87.1% were maintained on infliximab (median duration follow-up 85.9 weeks [Q1, Q3: 43.8, 138.8 weeks]). Infliximab optimization occurred in 57.3% (dose escalation 15.2%, interval shortening 3.9%, both 38.2%), primarily due to loss of response. Younger age at diagnosis (<10 years old) and nonstricturing, nonpenetrating behavior were associated with optimization (odds ratio 6.5, 95% confidence interval [CI] 2.0-21.1 and odds ratio 2.1, 95% CI 1.0-4.2, respectively). The 1- and 2-year durability of infliximab (percentage in follow-up who were continuing on infliximab) were 95.5% (95% CI 90.4-98.3) and 91.0% (95% CI 82.4-96.3), respectively. Annual discontinuation due to loss of response occurred at 3.2% per year (95% CI 1.1-5.2). Children with Crohn disease maintain a durable response to infliximab. Optimization occurs frequently and allows for continued use. Younger age at diagnosis and nonstricturing, nonpenetrating behavior are associated with increased need for infliximab optimization.
Quality of life and near vision impairment due to functional presbyopia among rural Chinese adults.
Lu, Qing; Congdon, Nathan; He, Xiangdong; Murthy, Gudlavalleti V S; Yang, Amy; He, Wei
2011-06-13
To evaluate the impact of near-vision impairment on visual functioning and quality of life in a rural adult population in Shenyang, northern China. A population-based, cross-sectional study was conducted among persons aged 40+ years, during which functional presbyopia (correctable presenting near vision < 20/50 [N8] at 40 cm) was assessed. Near-vision-related quality of life and spectacle usage questionnaires were administered by trained interviewers to determine the degree of self-rated difficulty with near tasks. A total of 1008 respondents (91.5% of 1102 eligible persons) were examined, and 776 (78%) of completed the questionnaires (mean age, 57.0 ± 10.2 years; 63.3% women). Near-vision spectacle wearers obtained their spectacles primarily from markets (74.5%) and optical shops (21.7%), and only 1.14% from eye clinics. Among 538 (69.3%) persons with functional presbyopia, self-rated overall (distance and near) vision was worse (P < 0.001) and difficulty with activities of daily living greater (P < 0.001) than among nonpresbyopes. Odds of reporting any difficulty with daily tasks remained higher (OR = 2.32; P < 0.001) for presbyopes after adjustment for age, sex, education and distance vision. Compared to persons without presbyopia, presbyopic persons were more likely to report diminished accomplishment due to vision (P = 0.01, adjusted for age, sex, education, and distance vision.) Difficulties with activities of daily living and resulting social impediments are common due to presbyopia in this setting. Most spectacle wearers with presbyopia in rural China obtain near correction from sources that do not provide comprehensive vision care.
RECOVERY OF VOCS FROM SURFACTANT SOLUTION BY PERVAPORATION
Surfactant-based processes are emerging as promising technologies to enhance conventional pump-and-treat methods for remediating soils contaminated with nonaqueous phase liquids (NAPLs), primarily due to the potential to significantly reduce the remediation time. In order to reus...
AN IMPROVED METHOD FOR DETECTING VIRUSES IN WATER
Enteroviruses are important etiological agents of waterborne disease and are responsible for outbreaks of gastroenteritis. However, the prevalence and occurrence of these pathogens in raw drinking water sources is poorly understood. This is primarily due to the limited methods ...
Hell, A K; Campbell, R M; Hefti, F
2005-01-01
Children with congenital thoracic scoliosis associated with fused ribs and unilateral unsegmented bars adjacent to convex hemivertebrae will inevitably develop thoracic insufficiency syndrome and curve progression with hemithorax compression without treatment. It is assumed that the concave side of such curves and their unilateral unsegmented bars do not grow. In the past early spinal fusion was performed with consecutive short thoracic spines and loss of lung volume. Little attention has been paid to lung function. These patients often suffered from lung failure and early death due to a small thorax. A new surgical technique is based on an indirect deformity correction and enlargement of the thorax due to a longitudinal implant, the vertical expandable prosthetic titanium rib (VEPTR). The spine is not fused, thus promoting growth of the spine, the thorax and the lungs. Elongation of the implant is done every six months. Since 2002 this method has been performed on fifteen children in Basel as the first European center. Patients (mean age 6 years; 11 months to 12 years) were suffering from thoracic insufficiency syndrome due to unilateral unsegmented bars with fused ribs (n = 4), absent ribs (n = 2), bilaterally fused ribs (n = 2), hemivertebrae (n = 3) or neuromuscular scoliosis (n = 6). Doing fifteen primarily implantations and thirteen elongations there were three complications (two hook dislocations, one skin breakage). All patients improved cosmetically, functionally and radiologically which was shown on X-rays as a reduction of the Cobb angle from an average of 76 degrees (40-110 degrees ) to 55 degrees (30-67 degrees ). Expansion thoracoplasty and VEPTR implantation is a new treatment concept for children with thoracic insufficiency syndrome due to spinal deformities, which is based on distraction and expansion of the thorax thus allowing growth of the spine, the thorax and probably lungs. Presently it seems to be superior to any other method for the treatment of small children with progressive scoliosis and thoracic insufficiency syndrome.
Knee joint pain potentially due to bone alterations in a knee osteoarthritis patient.
Komatsu, Masatoshi; Nakamura, Yukio; Kamimura, Mikio; Uchiyama, Shigeharu; Mukaiyama, Keijiro; Ikegami, Shota; Kato, Hiroyuki
2014-12-01
Osteoarthritis (OA) is the leading cause of musculoskeletal pain and functional disability worldwide. However, the etiology of this condition is still largely unknown. We report the clinical course of an elderly man with knee OA. Plain radiographs and MRI examinations performed during follow-up suggested that the pathophysiology of the patient's knee OA and joint pain may have been primarily due to bone alterations.
Mechanisms of poliovirus inactivation by the direct and indirect effects of ionizing radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ward, R.L.
1980-08-01
This study was designed to measure the effects of ionizing radiation on poliovirus particles when given under conditions where either direct (in broth) or indirect (in water) effects were predominant. Under direct conditions, inactivation of poliovirus was found to be due primarily to RNA damage, although capsid damage could account for about one-third of the viral inactivation. RNA damage did not appear to be due to strand breakage and therefore was probably caused primarily by base damage or crosslink formation. Capsid damage under direct irradiation conditions did not result in significant alterations of either the sedimentation coefficients or the isoelectricmore » points of the poliovirus particles or detectable modification of the sizes of the viral proteins. It did, however, cause loss of availability to bind to host cells. Under indirect conditions no more than 25% of viral inactivation appeared to be due to RNA damage. However, the sedimentation coefficients and isoelectric points of the viral particles were greatly altered, and their abilities to bind to cells were lost at about three-fourths the rate of loss of infectivity. Capsid damage in this case did result in changes in the sizes of capsid proteins. Therefore, the majority of the radiation inactivation under indirect conditions appeared to be due to protein damage.« less
The Jewish child, adolescent, and family.
Rube, David M; Kibel, Rabbi Nechemiah
2004-01-01
This brief review addresses the history, beliefs, and practices of Jewish families that have implications for clinical management of the problems and disorders of children and adolescents. It focuses primarily on the problems of the Orthodox family due, in part, to the limitations of space. There remains, however, little doubt that the clinician must be aware of the impact that Jewish heritage may have on the clinical issues at hand. This impact is significant whether the worldview of the family is characterized by strict Orthodoxy or is primarily that of an ethnic identification with less concern for belief and practice.
Harn, H J; Shen, K L; Ho, L I; Yu, K W; Liu, G C; Yueh, K C; Lee, J H
1997-01-01
AIMS: To determine, by strain identification of Mycobacterium tuberculosis, whether transmission has occurred between individuals or whether new strains are present. METHODS: A rapid protocol for random amplified polymorphic DNA (RAPD) analysis was developed. This protocol was applied to 64 strains of M tuberculosis that had been confirmed by culture and microbiological methods. RESULTS: There are five groups of M tuberculosis prevalent in Taipei city, Taiwan. The major types are groups I and III. Groups I and II had been prevalent until the end of last year when, according to our group analysis, they had been eradicated. However, group III was continuously present from the middle of 1995 to the middle of 1996, and group IV was present at the end of both years, which indicated that both groups were transmitted continuously. These clustered strains had demographic characteristics consistent with a finding of transmission tuberculosis. Also, there were 13 of 64 strains with unique RAPD fingerprints that were inferred to be due primarily to the reactivation of infection. In the drug resistance analysis, the major type represented included group III and part of group IV. CONCLUSIONS: Our preliminary data imply, not only that the prevalence of M tuberculosis in Taipei city is due to transmission rather than reactivation, but that drug resistance also may play a role in tuberculosis transmission. Images PMID:9378819
Earthquake and Tsunami History and Hazards of Eastern Indonesia
NASA Astrophysics Data System (ADS)
Major, J. R.; Robinson, J. S.; Harris, R. A.
2008-12-01
Western Indonesia (i.e. Java and Sumatra) has received much attention by geoscientists, especially in recent years due to events such as the Sumatra-Andaman event of 2004. However, the seismic history of eastern Indonesia is not widely known, notwithstanding the high rate of seismic activity in the area and high convergence rates. Not only do geologic hazards (i.e. strong earthquakes, tsunami, and explosive volcanoes) comparable to those in western part of the country exist, but population has increased nearly 10 fold in the last century. Our historical research of earthquakes and tsunami in eastern Indonesia based primarily on records of Dutch Colonists has uncovered a violent history of earthquakes and tsunami from 1608 to 1877. During this time eastern Indonesia experienced over 30 significant earthquakes and 35 tsunamis. Most of these events are much larger than any recorded in the last century. Due to this marked quiescence over the past century, and recent events in the Sunda arc over the past several years, we have initiated a new investigation of the region that integrates these historic events, field investigations, and, in the future, tsunami modeling. A more complete and comprehensive seismic history of eastern Indonesia is necessary for effective risk assessment. This information, along with renewed efforts by scientists and government will be crucial for disaster mitigation and to save lives.
The critical roles of information and nonequilibrium thermodynamics in evolution of living systems.
Gatenby, Robert A; Frieden, B Roy
2013-04-01
Living cells are spatially bounded, low entropy systems that, although far from thermodynamic equilibrium, have persisted for billions of years. Schrödinger, Prigogine, and others explored the physical principles of living systems primarily in terms of the thermodynamics of order, energy, and entropy. This provided valuable insights, but not a comprehensive model. We propose the first principles of living systems must include: (1) Information dynamics, which permits conversion of energy to order through synthesis of specific and reproducible, structurally-ordered components; and (2) Nonequilibrium thermodynamics, which generate Darwinian forces that optimize the system.Living systems are fundamentally unstable because they exist far from thermodynamic equilibrium, but this apparently precarious state allows critical response that includes: (1) Feedback so that loss of order due to environmental perturbations generate information that initiates a corresponding response to restore baseline state. (2) Death due to a return to thermodynamic equilibrium to rapidly eliminate systems that cannot maintain order in local conditions. (3) Mitosis that rewards very successful systems, even when they attain order that is too high to be sustainable by environmental energy, by dividing so that each daughter cell has a much smaller energy requirement. Thus, nonequilibrium thermodynamics are ultimately responsible for Darwinian forces that optimize system dynamics, conferring robustness sufficient to allow continuous existence of living systems over billions of years.
Modeling long-term carbon residue in the ocean-atmosphere system following large CO2 emissions
NASA Astrophysics Data System (ADS)
Towles, N. J.; Olson, P.; Gnanadesikan, A.
2013-12-01
We use the LOSCAR carbon cycle model (Zeebe et al., 2009; Zeebe, 2012) to calculate the residual carbon in the ocean and atmosphere following large CO2 emissions. We consider the system response to CO2 emissions ranging from 100 to 20000 PgC, and emission durations from 100 yr to 100 kyr, subject to a wide range of system parameters such as the strengths of silicate weathering and the oceanic biological carbon pump. We define the carbon gain factor as the ratio of residual carbon in the ocean-atmosphere to the total emitted carbon. For moderate sized emissions shorter than about 50 kyr, we find that the carbon gain factor grows during the emission and peaks at about 1.7, primarily due to the erosion of carbonate marine sediments. In contrast, for longer emissions, the carbon gain factor peaks at a smaller value, and for very large emissions (more than 5000 PgC), the gain factor decreases with emission size due to carbonate sediment exhaustion. This gain factor is sensitive to model parameters such as low latitude efficiency of the biological pump. The timescale for removal of the residual carbon (reducing the carbon gain factor to zero) depends strongly on the assumed sensitivity of silicate weathering to atmospheric pCO2, and ranges from less than one million years to several million years.
Comparison of Field Measurements to Methane Emissions ...
Due to both technical and economic limitations, estimates of methane emissions from landfills rely primarily on models. While models are easy to implement, there is uncertainty due to the use of parameters that are difficult to validate. The objective of this research was to compare modeled emissions using several greenhouse gas (GHG) emissions reporting protocols including: (1) Intergovernmental Panel on Climate Change (IPCC); (2) U.S. Environmental Protection Agency Greenhouse Gas Reporting Program (EPA GHGRP); (3) California Air Resources Board (CARB); (4) Solid Waste Industry for Climate Solutions (SWICS); and (5) an industry model from the Dutch waste company Afvalzorg, with measured data collected over 3 calendar years from a young landfill with no gas collection system. By working with whole landfill measurements of fugitive methane emissions and methane oxidation, the collection efficiency could be set to zero, thus eliminating one source of parameter uncertainty. The models consistently overestimated annual methane emissions by a factor ranging from 4 – 32.Varying input parameters over reasonable ranges reduced this range to 1.3 - 8. Waste age at the studied landfill was less than four years and the results suggest the need for measurements at additional landfills to evaluate the accuracy of the tested models to young landfills. This is a submission to a peer reviewed journal. The paper discusses landfill emission measurements and models for a new la
A rare case of non-surgical vocal cord paralysis: Vocal cord hematoma.
Arıkan, Akif Enes; Teksöz, Serkan; Bilgin, İsmail Ahmet; Tarhan, Özge; Özyeğin, Ateş
2017-01-01
Although vocal cord paralysis (VCP) following thyroidectomy is primarily associated with surgical trauma, it is not the sole etiology. Vocal cord paralysis following thyroidectomy can be caused by a vocal cord hematoma with an incidence of 1.4% due to direct injury during orotracheal intubation. In this article, we present a case of VCP caused by vocal cord hematoma. A 32-year-old male patient who has been receiving propylthiouracil treatment for toxic multinodular goiter since 10 years was admitted to our hospital to be operated because of persisting complaints. The patient was hospitalized for sutureless thyroidectomy after he became euthyroid. Preoperative fiberoptic laryngoscopy performed by the ear, nose, and throat department revealed bilaterally motile vocal folds and a completely open airway. Patient underwent sutureless total thyroidectomy with a vessel sealing device (Ligasure TM LF1212, Covidien, CO), and a minivac drainage system was placed in the thyroid lodge. On the morning of the first postoperative day, 50 mL of serosanguinous fluid was drained. The patient's voice was normal, and there was no ecchymosis. Postoperative fiberoptic laryngoscopy revealed a hematoma near the right vocal fold and paralysis of the right vocal fold; however, the airway was open. It should be kept in mind that VCP is not solely due to surgery but can also result from intubation, as observed in this case.
A rare case of non-surgical vocal cord paralysis: Vocal cord hematoma
Arıkan, Akif Enes; Teksöz, Serkan; Bilgin, İsmail Ahmet; Tarhan, Özge; Özyeğin, Ateş
2017-01-01
Although vocal cord paralysis (VCP) following thyroidectomy is primarily associated with surgical trauma, it is not the sole etiology. Vocal cord paralysis following thyroidectomy can be caused by a vocal cord hematoma with an incidence of 1.4% due to direct injury during orotracheal intubation. In this article, we present a case of VCP caused by vocal cord hematoma. A 32-year-old male patient who has been receiving propylthiouracil treatment for toxic multinodular goiter since 10 years was admitted to our hospital to be operated because of persisting complaints. The patient was hospitalized for sutureless thyroidectomy after he became euthyroid. Preoperative fiberoptic laryngoscopy performed by the ear, nose, and throat department revealed bilaterally motile vocal folds and a completely open airway. Patient underwent sutureless total thyroidectomy with a vessel sealing device (LigasureTM LF1212, Covidien, CO), and a minivac drainage system was placed in the thyroid lodge. On the morning of the first postoperative day, 50 mL of serosanguinous fluid was drained. The patient’s voice was normal, and there was no ecchymosis. Postoperative fiberoptic laryngoscopy revealed a hematoma near the right vocal fold and paralysis of the right vocal fold; however, the airway was open. It should be kept in mind that VCP is not solely due to surgery but can also result from intubation, as observed in this case. PMID:29260141
Epidemiology of childhood diabetes mellitus in Japan.
Tajima, Naoko; Morimoto, Aya
2012-10-01
The incidence of type 1 diabetes mellitus (T1DM) in Japan among those below 15 years of age is reportedly 1.5-2.5 per 100,000; however, population-based data have not been available in recent years. Although the incidence of T1DM in Japan is extremely low compared with that in Caucasians, the vast majority of Japanese children who are diagnosed with diabetes before the age of 10 years have T1DM. The incidence of type 2 diabetes mellitus (T2DM) in childhood is approximately 3.0 per 100,000, with the figure among junior high school children being 3-6 times higher than that among primary school children. The most common type of diabetes in children appears to shift from T1DM to T2DM with advancing age, especially after puberty. The mortality risk of patients with childhood-onset T1DM diagnosed between 1965 and 1979 is 12.9-fold higher than that of the general population. However, due to efforts aimed at improving medical care and ameliorating the effects of diabetes among children and adolescents, the standardized mortality ratio (SMR) has declined markedly over the past 30 years. The progression of complications in T2DM appears to be more rapid than that in T1DM, primarily due to the number of drop-out cases. Therefore, appropriate education and treatment programs are necessary to protect against diabetic complications in the younger generation. The establishment of an ongoing population-based national T1DM and T2DM registry system is critical for identifying risk factors associated with diabetes and its complications.
Sbordone, Carolina; Toti, Paolo; Guidetti, Franco; Califano, Luigi; Bufo, Pantaleo; Sbordone, Ludovico
2013-04-01
To evaluate long-term bone remodelling of autografts over time (annually, for 6 years), comparing the block and particulate bone procedures for sinus floor elevation, as well as to evaluate the survival of positioned dental implants. Twenty-three sinus lift procedures with autogenous bone were performed: seven sinus lift procedures using particulate graft and 10 with block autogenous bone were performed in 17 patients. Employing a software program, pre- and post-surgical computerized tomography (CT) scans were used to compare the volume (V) and density (D) of inlay grafts over time (up to 6 years), and to determine the percentage of remaining bone (%R). All variable (V, D and %R) measurements were then compared statistically. At the 6-year survey for block form, a resorption of 21.5% was seen, whereas for particulate grafts there was a resorption of 39.2%. Both groups exhibited bone remodelling between the first and second follow-up which was significant regarding volume for the block form and regarding density for the particulate group. During the initial period of healing, the cortico-cancellous block bone grafted into the maxillary sinus underwent a negative remodelling of the volume, which is most probably due to graft cortex resorption, coupled with, primarily, an increase in density in the spongious area; for the particulate grafts, significant augmentations in density were obtained. The lack of significant differences among volumes was due to the wide degree of dispersion of the data. The rough data presented in this paper seem to support the use of a bone-block grafting procedure in maxillary sinus augmentation. Copyright © 2012 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
Surveillance of Suicidal Behavior January through December 2013
2015-06-01
primarily for cannabis and cocaine. The prevalence of being screened for ASAP was: - 19%, suicide cases; of those, 57% enrolled in the program...year of their death. Positive tests were primarily for cannabis (50%), cocaine (35%), and amphetamines (18%). Of suicide cases from 2001...their death. Drugs with Positive Tests: Positive tests were for cannabis (50%), oxycodone (33%) and cocaine (17%). ASAP Screening
ERIC Educational Resources Information Center
Woodruff, Barbara Bilson, Ed.
1988-01-01
Designed primarily for English faculty at community colleges in California, "Inside English" includes articles on instructional innovations in teaching remedial writing, literature courses, and freshman composition, and on major curricular, administrative, and employment issues in the field. The first issue of volume 15 focuses primarily on…
The acute neurobehavioral effects of acetylcholinesterase-inhibiting pesticides are primarily due to overstimulation of the cholinergic system. Lowered motor activity levels represent a sensitive endpoint with which to monitor functional changes in laboratory animals exposed to ...
MERCURY CONTROL IN MUNICIPAL WASTE COMBUSTORS AND COAL-FIRED UTILITIES
Control of mercury (Hg) emissions from municipal waste combustors (MWCs) and coal-fired utilities has attracted attention due to current and potential regulations. Among several techniques evaluated for Hg control, dry sorbent injection (primarily injection of activated carbon) h...
Connecting People to Places : Spatiotemporal Analysis of Transit Supply Using Travel Time Cubes
DOT National Transportation Integrated Search
2016-06-01
Despite its importance, temporal measures of accessibility are rarely used in transit research or practice. This is primarily due to the inherent difficulty and complexity in computing time-based accessibility metrics. Estimating origin-to-destinatio...
TRANSPORT OF TRICHLOROETHYLENE (TCE) IN NATURAL SOIL BY ELECTROOSMOSIS
Contamination in low permeability soils poses a significant technical challenge to in-situ remediation, primarily due to low mobilization of the contaminants and difficulty in uniform delivery of treatment reagents. An alternative approach using electroosmosis (EO) is used to mob...
Design parameters and methodology for mechanically stabilized earth (MSE) walls.
DOT National Transportation Integrated Search
2014-10-01
Since its appearance in 1970s, mechanically stabilized earth (MSE) walls have become a majority among all types of retaining walls due to their economics and satisfactory performance. The Texas Department of Transportation (TxDOT) has primarily adopt...
AIR TOXICS EMISSIONS FROM ELECTRONICS INCINERATION
The purpose of this project is to examine the emissions of air toxics from the combustion of electronics equipment, primarily personal computer components. Due to a shortage of recycling programs for personal computers and other personal electronics equipment, most of these mate...
7 CFR 1980.302 - Definitions and abbreviations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... of years but has during such years worked primarily without remuneration to care for the home and... custody of one or more minor children or is pregnant. State Director. Director of RHS programs within a...
Clinical utility of curcumin extract.
Asher, Gary N; Spelman, Kevin
2013-01-01
Turmeric root has been used medicinally in China and India for thousands of years. The active components are thought to be the curcuminoids, primarily curcumin, which is commonly available worldwide as a standardized extract. This article reviews the pharmacology of curcuminoids, their use and efficacy, potential adverse effects, and dosage and standardization. Preclinical studies point to mechanisms of action that are predominantly anti-inflammatory and antineoplastic, while early human clinical trials suggest beneficial effects for dyspepsia, peptic ulcer, inflammatory bowel disease, rheumatoid arthritis, osteoarthritis, uveitis, orbital pseudotumor, and pancreatic cancer. Curcumin is well-tolerated; the most common side effects are nausea and diarrhea. Theoretical interactions exist due to purported effects on metabolic enzymes and transport proteins, but clinical reports do not support any meaningful interactions. Nonetheless, caution, especially with chemotherapy agents, is advised. Late-phase clinical trials are still needed to confirm most beneficial effects.
Effects of cognitive training on change in accuracy in inductive reasoning ability.
Boron, Julie Blaskewicz; Turiano, Nicholas A; Willis, Sherry L; Schaie, K Warner
2007-05-01
We investigated cognitive training effects on accuracy and number of items attempted in inductive reasoning performance in a sample of 335 older participants (M = 72.78 years) from the Seattle Longitudinal Study. We assessed the impact of individual characteristics, including chronic disease. The reasoning training group showed significantly greater gain in accuracy and number of attempted items than did the comparison group; gain was primarily due to enhanced accuracy. Reasoning training effects involved a complex interaction of gender, prior cognitive status, and chronic disease. Women with prior decline on reasoning but no heart disease showed the greatest accuracy increase. In addition, stable reasoning-trained women with heart disease demonstrated significant accuracy gain. Comorbidity was associated with less change in accuracy. The results support the effectiveness of cognitive training on improving the accuracy of reasoning performance.
Instability of multistage compressor K1501
NASA Technical Reports Server (NTRS)
Zhou, Ren-Mu
1987-01-01
The K1501 compressor, driven by a steam turbine, is used to transport synthetic gas in fertilizer plants of 1000 tons daily production. The turbo-compressor set, which had been in operation since 1982, vibrated rather intensely, and its maximum load was only about 95 percent of the normal value. Damaging vibration to pads and gas-sealing labyrinths occurred three times from 1982 to 1983 and resulted in considerable economic loss. From the characteristics of the vibration, we suspected its cause to be rotor instability due to labyrinth-seal excitation. But, for lack of experience, the problem was not addressed for two years. Finally, we determined that the instability was indeed produced by labyrinth-seal excitation and corrected this problem by injecting gas into the middle-diaphragm labyrinths. This paper primarily discusses the failure and the remedy described above.
Schenker, Victoria J.; Petrill, Stephen A.
2015-01-01
This study investigated the genetic and environmental influences on observed associations between listening comprehension, reading motivation, and reading comprehension. Univariate and multivariate quantitative genetic models were conducted in a sample of 284 pairs of twins at a mean age of 9.81 years. Genetic and nonshared environmental factors accounted for statistically significant variance in listening and reading comprehension, and nonshared environmental factors accounted for variance in reading motivation. Furthermore, listening comprehension demonstrated unique genetic and nonshared environmental influences but also had overlapping genetic influences with reading comprehension. Reading motivation and reading comprehension each had unique and overlapping nonshared environmental contributions. Therefore, listening comprehension appears to be related to reading primarily due to genetic factors whereas motivation appears to affect reading via child-specific, nonshared environmental effects. PMID:26321677
Schenker, Victoria J; Petrill, Stephen A
2015-01-01
This study investigated the genetic and environmental influences on observed associations between listening comprehension, reading motivation, and reading comprehension. Univariate and multivariate quantitative genetic models were conducted in a sample of 284 pairs of twins at a mean age of 9.81 years. Genetic and nonshared environmental factors accounted for statistically significant variance in listening and reading comprehension, and nonshared environmental factors accounted for variance in reading motivation. Furthermore, listening comprehension demonstrated unique genetic and nonshared environmental influences but also had overlapping genetic influences with reading comprehension. Reading motivation and reading comprehension each had unique and overlapping nonshared environmental contributions. Therefore, listening comprehension appears to be related to reading primarily due to genetic factors whereas motivation appears to affect reading via child-specific, nonshared environmental effects. Copyright © 2015 Elsevier Inc. All rights reserved.
Ten-year cardiovascular risk assessment in university students.
Uvacsek, Martina; Kneffel, Zs; Tóth, M; Johnson, A W; Vehrs, P; Myrer, J W; Hager, R
2014-09-01
Cardiovascular disease (CVD) is responsible for more than half of all deaths in the European region. The aim of the study was to compare body composition, blood pressure, total cholesterol (TC) and high density lipoprotein cholesterol (HDL-C), family history, activity behaviors, and the 10-year risk of having a heart attack between 166 university students (21.62 ± 2.59 yrs) from Utah (USA) and 198 students (22.11 ± 2.51 yrs) from Hungary. Ninety-two percent of the Hungarian students and 100% of the Utah students had an estimated 10-year Framingham risk score of 1% or less. The high prevalence of low risk was primarily due to the young age of study participants, healthy body composition and non-smoking behavior. Hungarians who had higher 10-year risk of heart attack had significantly higher waist hip ratio (WHR), TC, diastolic blood pressure (DBP) and were smokers compared to those Hungarians with lower risk. The self-reported physical activity levels between the two groups of students were not different. In conclusion the young men and women who participated in this study were, for the most part healthy; however the smoking habits and the lower physical activity of the Hungarian students likely elevated their risk of CVD.
Keage, Hannah A D; Smith, Ashleigh; Loetscher, Tobias; Psaltis, Peter
2016-12-01
Older individuals can now undergo invasive cardiovascular procedures without serious concern about mortality, and the numbers and proportions of the over 65s and 85s doing so in Australia has been increasing over the last 20 years. There is overwhelming evidence linking cardiovascular conditions to late-life (65 years and over) cognitive impairment and dementia including Alzheimer's Disease, primarily due to impaired cerebrovascularisation and cascading neuropathological processes. Somewhat paradoxically, these cardiovascular interventions, carried out with the primary aim of revascularisation, are not usually associated with short- or long-term improvements in cognitive function in older adults. We discuss factors associated with cognitive outcomes post-cardiovascular surgeries in patients over 65 years of age. There are many opportunities for future research: we know almost nothing about cognitive outcomes following invasive cardiac procedures in the oldest old (85 years and over) nor how to predict the cognitive/delirium outcome using pre-surgical data, and lastly, intervention opportunities exist both pre and postoperatively that have not been tested. As our population ages with increased cardiovascular burden and rates of cardiovascular interventions and surgeries, it is critical that we understand the cognitive consequences of these procedures, who is at greatest risk, and ways to optimise cognition. Copyright © 2016. Published by Elsevier B.V.
Chlorophyll-a Concentrations Affected by Discharge and Climate Conditions in Galveston Bay, Texas
NASA Astrophysics Data System (ADS)
Shen, X.; Gao, H.; Zhang, S.
2017-12-01
As the transition zones between river and ocean, estuaries face increasing pressure on their ecosystem health due to changes of freshwater quantity and quality—especially under the impacts of population growth, land use/land cover change, and climate change. Located at the northeast of Houston, Galveston Bay is of particular social economic importance for the State of Texas. Its freshwater inflow primarily arises from two rivers, the San Jacinto and the Trinity. While it is well recognized that Chlorophyll a (chla) concentration—an indicator of ecosystem health—is closely linked to river inflows and other environmental factors, no quantitative relationships have been established. The objectives of this study are to identify the spatial-temporal variations of chla, and to investigate the impacts of freshwater inflow and climatic factors on chla variability—so that prediction models can be developed for chla forecasting to provide scientific support for ecological management (in Galveston Bay). A 10-year validated remote sensing dataset is used in this analysis. The results show that chla has higher concentrations near the shoreline, as compared to the center of the bay. Temporally, chla tends to be higher in wet years than in dry years. Similarly, the seasonal fluctuations of chla are more significant during the wet months (from February to May) than the dry months (especially from August to December). Chla in the bay is primarily determined by discharge from the Trinity River in AMJ (April, May, June) and JAS (July, August, September). However, the driving factor is mainly water temperature in OND (October, November, December). In JFM (January, February, March), almost all of the factors (except discharge from the San Jacinto River) show significant correlation with chla. Based on these analyses, a chla prediction model is developed and tested. This result can provide scientific support for coastal environmental management in Galveston Bay, maintaining the eco-environmental health and reducing eutrophication risk in the future.
Alpizar, D; Fallas, M; Oehlschlager, A C; Gonzalez, L M
2012-03-01
Mass trapping Cosmopolites sordidus (Coleoptera, Curculionidae) using a pheromone-baited pitfall trap and Metamasius hemipterus (Coleoptera, Curculionidae) using a pheromone-sugarcane-baited open gallon trap was conducted in commercial banana. Four traps for each insect per hectare were placed in each of two 5-hectare plots of banana. Two additional 5-hectare plots were designated as controls and treated according to the plantation protocol. Capture rates of C. sordidus and M. hemipterus declined by >75 % over 10-12 months. In the banana growing region studied, corm damage was due primarily to C. sordidus, while only a minor amount of damage was attributable to M. hemipterus. Corm damage reduction in trapping plots was, thus, attributed primarily to C. sordidus trapping. In trapping plots, corm damage decreased by 61-64 % during the experiment. Banana bunch weights increased 23 % relative to control plots after 11-12 months of trapping. Fruit diameter did not vary between bunches harvested from trapping plots vs. control plots. Plant vigor, however, as determined by stem circumference at one meter above ground increased in plots with traps compared to control plots. Trapping for C. sordidus in two plantations of over 200 hectares each, reduced corm damage 62-86 % relative to pre-trapping levels. Insecticide control measures in place when the experiment commenced resulted in about 20-30 % corm damage, while use of pheromone trapping to manage C. sordidus lowered corm damage to 10 % or less. It is estimated that the increase in value of increased yield obtained in this trial (23 %) is about $4,240 USD per year per hectare, while the cost of pheromone trapping is approximately $185 USD per year per hectare. The trapping program becomes revenue neutral if bunch weights increase by an average of 1 % per year of trapping. Approximately 10 % of all plantation area in Costa Rica use the pheromone trapping system described here. The system also is used in Martinique, Guadeloupe, and the Canary Islands.
Wilson, R.R.; Twedt, D.J.; Fredrickson, L.H.; King, S.L.; Kaminski, R.M.
2005-01-01
Reforestation of bottomland hardwood sites in the Mississippi Alluvial Valley has markedly increased in recent years, primarily due to financial incentive programs such as the Wetland Reserve Program, Partners for Wildlife Program, and state and private conservation programs. An avian conservation plan for the Mississippi Alluvial Valley proposes returning a substantial area of cropland to forested wetlands. Understanding how birds colonize reforested sites is important to assess the effectiveness of avian conservation. We evaluated establishment of woody species and assessed bird colonization on 89 reforested sites. These reforested sites were primarily planted with heavy-seeded oaks (Quercus spp.) and pecans (Carya illinoensis). Natural invasion of light-seeded species was expected to diversify these forests for wildlife and sustainable timber harvest. Planted tree species averaged 397 + 36 stems/ha-1, whereas naturally invading trees averaged 1675 + 241 stems/ha. However, naturally invading trees were shorter than planted trees and most natural invasion occurred <100 m from an existing forested edge. Even so, planted trees were relatively slow to develop vertical structure, especially when compared with tree species planted and managed for pulpwood production. Slow development of vertical structure resulted in grassland bird species, particularly dickcissel (Spiza americana) and red-winged blackbird (Agelaius phoeniceus), being the dominant avian colonizers for the first 7 years post-planting. High priority bird species (as defined by Partners in Flight), such as prothonotary warbler (Protonotaria citrea) and wood thrush (Hylocichla mustelina), were not frequently detected until stands were 15 years old. Canonical correspondence analysis revealed tree height had the greatest influence on the bird communities colonizing reforested sites. Because colonization by forest birds is dependent on tree height, we recommend inclusion of at least one fast-growing tree species (e.g., cottonwood [Populus deltoides], or sycamore [Platanus occidentalis]) in the planting stock to encourage rapid avian colonization.
Rao, Leela E; Allen, Edith B
2010-04-01
Primary production in deserts is limited by soil moisture and N availability, and thus is likely to be influenced by both anthropogenic N deposition and precipitation regimes altered as a consequence of climate change. Invasive annual grasses are particularly responsive to increases in N and water availabilities, which may result in competition with native forb communities. Additionally, conditions favoring increased invasive grass production in arid and semi-arid regions can increase fire risk, negatively impacting woody vegetation that is not adapted to fire. We conducted a seeded garden experiment and a 5-year field fertilization experiment to investigate how winter annual production is altered by increasing N supply under a range of water availabilities. The greatest production of invasive grasses and native forbs in the garden experiment occurred under the highest soil N (inorganic N after fertilization = 2.99 g m(-2)) and highest watering regime, indicating these species are limited by both water and N. A classification and regression tree (CART) analysis on the multi-year field fertilization study showed that winter annual biomass was primarily limited by November-December precipitation. Biomass exceeded the threshold capable of carrying fire when inorganic soil N availability was at least 3.2 g m(-2) in piñon-juniper woodland. Due to water limitation in creosote bush scrub, biomass exceeded the fire threshold only under very wet conditions regardless of soil N status. The CART analyses also revealed that percent cover of invasive grasses and native forbs is primarily dependent on the timing and amount of precipitation and secondarily dependent on soil N and site-specific characteristics. In total, our results indicate that areas of high N deposition will be susceptible to grass invasion, particularly in wet years, potentially reducing native species cover and increasing the risk of fire.
NASA Astrophysics Data System (ADS)
Charalampidis, C.; van As, D.; Machguth, H.; Smeets, P.; van den Broeke, M. R.; Box, J. E.
2014-12-01
We present five years (2009-2013) of automatic weather station (AWS) data from the lower accumulation area (1840 m above sea level) of the Kangerlussuaq region, western Greenland ice sheet. The summers of 2010 and 2012 were both exceptionally warm, but only 2012 resulted in negative surface mass budget (SMB) and surface runoff. The observed runoff was due to a large ice fraction in the upper 10 m of firn that prevented melt water from percolating to available pore space below. Analysis of the in situ data reveals a relatively low 2012 summer albedo of ~0.7 as melt water was present at the surface. Consequently, during the 2012 melt season the surface absorbed 30% (213 MJ m-2) more solar radiation than in 2010. We drive a surface energy balance model with the AWS data to evaluate the seasonal and interannual variability of all surface energy fluxes. The model is able to reproduce the observed melt rates as well as the SMB for each season. While the drive for melt is solar radiation, year-to-year differences are controlled by terrestrial radiation, apart from 2012 when solar radiation dominated melt. Sensitivity tests reveal that 72% of the excess solar energy in 2012 was used for melt, corresponding to 40% (0.67 m) of the 2012 surface ablation. The remaining ablation (0.99 m) was primarily due to the relatively high atmospheric temperatures up to +2.6 °C daily average, indicating that 2012 would have been a negative SMB year in the lower accumulation area even without the melt-albedo feedback. Longer time series of SMB, regional temperature and remotely sensed albedo (MODIS) suggest that 2012 was the first negative SMB year with the lowest albedo at this elevation on record. The warming conditions of the last years resulted in enhanced melt and reduction of the refreezing capacity of the lower accumulation area. If the warming continues the lower accumulation area will be transformed into superimposed ice.
Rickets–vitamin D deficiency and dependency
Sahay, Manisha; Sahay, Rakesh
2012-01-01
Rickets is an important problem even in countries with adequate sun exposure. The causes of rickets/osteomalacia are varied and include nutritional deficiency, especially poor dietary intake of vitamin D and calcium. Non-nutritional causes include hypophosphatemic rickets primarily due to renal phosphate losses and rickets due to renal tubular acidosis. In addition, some varieties are due to inherited defects in vitamin D metabolism and are called vitamin D dependent rickets. This chapter highlights rickets/osteomalacia related to vitamin D deficiency or to inherited defects in vitamin D metabolism. Hypophosphatemic rickets and rickets due to renal tubular acidosis are discussed in other sections of the journal. PMID:22470851
NIH's National Institute of General Medical Sciences celebrates 45 years of Discovery for Health
... Alison Davis NIH's National Institute of General Medical Sciences celebrates 45 years of Discovery for Health The National Institute of General Medical Sciences (NIGMS) is the NIH institute that primarily supports ...
Physiology and biochemistry of honey bees
USDA-ARS?s Scientific Manuscript database
Despite their tremendous economic importance, honey bees are not a typical model system for studying general questions of insect physiology. This is primarily due to the fact that honey bees live in complex social settings which impact their physiological and biochemical characteristics. Not surpris...
DOT National Transportation Integrated Search
2016-05-23
In spite of various advancements in vehicle safety technologies and improved roadway design practices, roadway crashes remain a major challenge. While certain hotspots may be unsafe primarily due to the geometric features of these locations, in many ...
Malignant catarrhal fever: understanding molecular diagnostics in context of epidemiology
USDA-ARS?s Scientific Manuscript database
Malignant catarrhal fever (MCF) is a frequently fatal disease, primarily of ruminants, caused by a group of gammaherpesviruses. Due to complexities of pathogenesis and epidemiology in various species which are either clinically-susceptible or reservoir hosts, veterinary clinicians face significant ...
Academic Misguidance in Colleges and Universities.
ERIC Educational Resources Information Center
Zirkel, Perry A.; Hugel, Paul S.
1989-01-01
Examines the various legal remedies that students, believing that they have been victims of misguidance, have pursued against institutions of higher education. The legal theories available primarily fit in four categories: (1) estoppel; (2) fraud; (3) breach of contract; and (4) due process. (MLF)
Epidemiology: Malaria in a warmer West Africa
NASA Astrophysics Data System (ADS)
Caminade, C.; Jones, A. E.
2016-11-01
Malaria risk in West Africa is expected to fall (western region) or remain the same (eastern region) in response to climate change over the twenty-first century. This is primarily due to extreme temperature conditions projected under a high greenhouse gas emissions scenario.
POLYBROMINATED DIPHENYL ETHERS IN SOUTHERN MISSISSIPPI CATFISH
Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide variety of consumer products. Concerns surrounding these compounds are primarily due do their ubiquitous presence in the environment as well as in human tissue, such as milk, coupled with evidence indi...
Performance and design of bridge approach panels in Wisconsin.
DOT National Transportation Integrated Search
2015-02-01
Within the recent past, the Wisconsin DOT changed the bridge approach slab design from a system using only one expansion joint to a system using three expansion joints. This change was due primarily to the need to accommodate differential expansion a...
Bovine tuberculosis research: Immune mechanisms relevant to biomedical applications
USDA-ARS?s Scientific Manuscript database
Pioneer studies on infectious disease and immunology by Jenner, Pasteur, Koch, Von Behring, Nocard, Roux, and Ehrlich forged a path for the dual-purpose with dual benefit approach, clearly demonstrating the relevance of veterinary studies for biomedical applications. Tuberculosis (TB), primarily due...
RELATIVE BINDING AFINITY OF ALKYLPHENOLS TO RAINBOW TROUT ESTROGEN RECEPTOR
The USEPA has been mandated to screen industrial chemicals and pesticides for potential endocrine activity. The appropriateness of extrapolating mammalian results to non-mammalian species is uncertain; primarily due to the lack of non-mammalian data for making such an assessment....
ERIC Educational Resources Information Center
Schumacker, Randall E.; Smith, Everett V., Jr.
2007-01-01
Measurement error is a common theme in classical measurement models used in testing and assessment. In classical measurement models, the definition of measurement error and the subsequent reliability coefficients differ on the basis of the test administration design. Internal consistency reliability specifies error due primarily to poor item…
Spehar, Daniel D.; Wolf, Peter J.
2018-01-01
Simple Summary Dramatic declines in the number of cats admitted to and euthanized at U.S. shelters have taken place in recent decades. Still, millions of cats, many of them free-roaming, enter shelters each year. At some facilities, as many as 70% of feline admissions are euthanized, and it is estimated that, nationally, up to one million or more cats are euthanized each year. New approaches, including return-to-field (RTF) and targeted trap-neuter-return (TNR) appear to have transformative potential. The present study examines changes in feline intake and euthanasia, as well as impacts on associated metrics, at a municipal animal shelter in Albuquerque, New Mexico, after formal RTF and targeted TNR protocols, collectively referred to as a community cat program (CCP), were added to ongoing community-based TNR efforts and a pilot RTF initiative. As part of the three-year CCP, 11,746 cats were trapped, sterilized, vaccinated and returned or adopted. Feline euthanasia at the Albuquerque Animal Welfare Department (AAWD) declined by 84.1% and feline intake dropped by 37.6%; the live release rate (LRR) increased by 47.7% due primarily to these reductions in both intake and euthanasia. Modest increases in the percentage of cats returned to owner (RTO) and the adoption rate were also observed, although both metrics decreased on an absolute basis, while the number of calls to the city about dead cats declined. Abstract Available evidence indicates that overall levels of feline intake and euthanasia at U.S. shelters have significantly declined in recent decades. Nevertheless, millions of cats, many of them free-roaming, continue to be admitted to shelters each year. In some locations, as many as 70% of cats, perhaps up to one million or more per year nationally, are euthanized. New approaches, including return-to-field (RTF) and targeted trap-neuter-return (TNR) appear to have transformative potential. The purpose of the present study was to examine changes in feline intake and euthanasia, as well as additional associated metrics, at a municipal animal shelter in Albuquerque, New Mexico, after institutionalized RTF and targeted TNR protocols, together referred to as a community cat program (CCP), were added to ongoing community-based TNR efforts and a pilot RTF initiative. Over the course of the CCP, which ran from April 2012 to March 2015, 11,746 cats were trapped, sterilized, vaccinated, and returned or adopted. Feline euthanasia at the Albuquerque Animal Welfare Department (AAWD) declined by 84.1% and feline intake dropped by 37.6% over three years; the live release rate (LRR) increased by 47.7% due primarily to these reductions in both intake and euthanasia. Modest increases in the percentage of cats returned to owner (RTO) and the adoption rate were also observed, although both metrics decreased on an absolute basis, while the number of calls to the city about dead cats declined. PMID:29652808
Quality-of-life effects of prostate-specific antigen screening
Heijnsdijk, EAM; Wever, EM; Auvinen, A; Hugosson, J; Ciatto, S; Nelen, V; Kwiatkowski, M; Villers, A; Páez, A; Moss, SM; Zappa, M; Tammela, TLJ; Mäkinen, T; Carlsson, S; Korfage, IJ; Essink-Bot, ML; Otto, SJ; Draisma, G; Bangma, CH; Roobol, MJ; Schröder, FH; de Koning, HJ
2016-01-01
Background The European Randomized Study of Screening for Prostate Cancer (ERSPC) reported a 29% prostate cancer mortality reduction among screened men after 11 years. However, it is uncertain to what extent harms from overdiagnosis and treatment on quality of life counterbalance this benefit. Methods Based on ERSPC follow-up data, we used micro-simulation modeling (MISCAN) to predict the number of prostate cancers, treatments, deaths and quality-adjusted life-years (QALYs) gained following the introduction of screening. Various screening strategies, efficacies, and quality of life assumptions were modeled. Results Per 1,000 men of all ages followed for their entire lifespan we predicted for annual screening from age 55–69 years: 9 fewer deaths due to prostate cancer (28% reduction), 14 fewer men receiving palliative therapy (35% reduction), and 73 life-years gained (average 8.4 years per prostate cancer death avoided). QALYs gained were 56 (range: −21, 97), a reduction of 23% from unadjusted life-years gained. The number needed to screen (NNS) was 98 and number needed to detect (NND) 5. Also inviting men aged 70–74 resulted in more life-years (82) but similar QALYs (56). Conclusions Although NNS and NND are more favorable than previously calculated, the benefit of PSA screening is diminished by loss of QALYs, that is dependent primarily on post-diagnosis long-term effects. Longer follow-up data from both the ERSPC and quality of life are essential before making universal recommendations regarding screening. PMID:22894572
Sculley, John B.; Lowe, Rex L.; Nittrouer, Charles A.; Drexler, Tina M.; Power, Mary E.
2017-01-01
Little is known about the importance of food-web processes as controls of river primary production due to the paucity of both long-term studies and of depositional environments which would allow retrospective fossil analysis. To investigate how freshwater algal production in the Eel River, northern California, varied over eight decades, we quantified siliceous shells (frustules) of freshwater diatoms from a well-dated undisturbed sediment core in a nearshore marine environment. Abundances of freshwater diatom frustules exported to Eel Canyon sediment from 1988 to 2001 were positively correlated with annual biomass of Cladophora surveyed over these years in upper portions of the Eel basin. Over 28 years of contemporary field research, peak algal biomass was generally higher in summers following bankfull, bed-scouring winter floods. Field surveys and experiments suggested that bed-mobilizing floods scour away overwintering grazers, releasing algae from spring and early summer grazing. During wet years, growth conditions for algae could also be enhanced by increased nutrient loading from the watershed, or by sustained summer base flows. Total annual rainfall and frustule densities in laminae over a longer 83-year record were weakly and negatively correlated, however, suggesting that positive effects of floods on annual algal production were primarily mediated by “top-down” (consumer release) rather than “bottom-up” (growth promoting) controls. PMID:28874576
Schamber, Jason L.
2010-01-01
Abundance indices of Black Scoters (Melanitta nigra. americana) breeding in Alaska indicate a long-term population decline without obvious cause (s). However, few life history data are available for the species in North America. In 2001–2004, information was collected on nesting habitat and reproductive parameters (i.e. components of productivity) from a population of Black Scoters nesting on the Yukon-Kuskokwim Delta, Alaska. A total of 157 nests were found over four years. Primarily, nests were among dense vegetation in shrub edge habitat, predominantly dwarf birch (Betula glandulosa) and Alaska spiraea (Spiraea beauverdiana), an average of 58 m from water. Females initiated nests from 11 June and 17 July across years. Clutch size averaged 7.5 eggs and did not vary annually. Nest success was highly variable among years and ranged from 0.01 to 0.37. Duckling survival to 30 days old varied among years, and ranged from 0.09 – 0.35. Nest success was poor in three of four years, likely due to predation by Red Fox (Vulpes vulpes). Black Scoters appear to have low but variable productivity, consistent with life-history patterns of other sea duck species. Information gained will direct future demographic research on Black Scoters, and highlights knowledge gaps impeding management strategies needed for population recovery.
Sculley, John B; Lowe, Rex L; Nittrouer, Charles A; Drexler, Tina M; Power, Mary E
2017-09-19
Little is known about the importance of food-web processes as controls of river primary production due to the paucity of both long-term studies and of depositional environments which would allow retrospective fossil analysis. To investigate how freshwater algal production in the Eel River, northern California, varied over eight decades, we quantified siliceous shells (frustules) of freshwater diatoms from a well-dated undisturbed sediment core in a nearshore marine environment. Abundances of freshwater diatom frustules exported to Eel Canyon sediment from 1988 to 2001 were positively correlated with annual biomass of Cladophora surveyed over these years in upper portions of the Eel basin. Over 28 years of contemporary field research, peak algal biomass was generally higher in summers following bankfull, bed-scouring winter floods. Field surveys and experiments suggested that bed-mobilizing floods scour away overwintering grazers, releasing algae from spring and early summer grazing. During wet years, growth conditions for algae could also be enhanced by increased nutrient loading from the watershed, or by sustained summer base flows. Total annual rainfall and frustule densities in laminae over a longer 83-year record were weakly and negatively correlated, however, suggesting that positive effects of floods on annual algal production were primarily mediated by "top-down" (consumer release) rather than "bottom-up" (growth promoting) controls.
Soh, May Ching; Nelson-Piercy, Catherine; Dib, Fadia; Westgren, Magnus; McCowan, Lesley; Pasupathy, Dharmintra
2015-09-01
To determine if maternal placental syndromes (MPS) are associated with an increased risk of death from cardiovascular causes in women with systemic lupus erythematosus (SLE). Between 1973 and 2011, women with SLE and a history of pregnancy were identified using linked Swedish population registries. The outcome was death from primarily cardiovascular causes, defined as death from acute coronary syndrome or coronary artery disease, stroke, or peripheral vascular disease. The exposure was MPS, defined as any hypertensive disorders in pregnancy, stillbirth, placental abruption, or delivery of a small-for-gestational-age infant. The association of preterm delivery (delivery at <34 weeks of gestation) with death from cardiovascular causes was also explored. Risk of death from cardiovascular causes was determined using logistic regression, adjusting for the year of first delivery, duration of SLE, number of inpatient admissions, and cardiovascular risk factors. A total of 3,977 women with SLE had 7,410 pregnancies during the study interval. Death from primarily cardiovascular causes occurred in 44 of the 325 women who died (13.5%). The median age at death from cardiovascular causes was 54 years (interquartile range 48-58 years), and these women were more likely to have had hypertension and renal disease. MPS was associated with an increased risk of death from primarily cardiovascular causes (adjusted odds ratio [OR] 2.19 [95% confidence interval (95% CI) 1.14-4.22]), specifically, a history of placental abruption (adjusted OR 5.78 [95% CI 1.61-20.72]). Delivery at <34 weeks of gestation, particularly when combined with MPS, was also associated with an increased risk of death from primarily cardiovascular causes (adjusted OR 2.49 [95% CI 1.06-5.85]). MPS in pregnancy is associated with a higher risk of death from primarily cardiovascular causes in women with SLE. © 2015, American College of Rheumatology.
NASA Astrophysics Data System (ADS)
Woodgate, Rebecca A.
2018-01-01
Year-round in situ Bering Strait mooring data (1990-2015) document a long-term increase (∼0.01 Sv/yr) in the annual mean transport of Pacific waters into the Arctic. Between 2002 and 2015, all annual mean transports (except 2005 and 2012) are greater than the previously accepted climatology (∼0.8 Sv). The record-length maximum (2014: 1.2 ± 0.1 Sv) is 70% higher than the record-length minimum (2001: 0.7 ± 0.1 Sv), corresponding to a reduction in the flushing time of the Chukchi Sea (to ∼4.5 months from ∼7.5 months). The transport increase results from stronger northward flows (not fewer southward flow events), yielding a 150% increase in kinetic energy, presumably with impacts on bottom suspension, mixing, and erosion. Curiously, we find no significant trends in annual mean flow in the Alaskan Coastal Current (ACC), although note that these data are only available 2002-2015. Record-length trends in annually integrated heat and freshwater fluxes (primarily driven by volume flux trends) are large (0.06 ± 0.05 × 1020 J/yr; 30 ± 20 km3/yr; relative to -1.9 °C and 34.8 psu), with heat flux lows in 2001 and 2012 (∼3 × 1020 J) and highs in 2007 and 2015 (∼5.5 × 1020 J), and a freshwater range of ∼2300 km3 (2001) to ∼3500 km3 (2014). High-flow year 2015 (volume transport ∼1.1 Sv) has the highest annual mean temperature recorded, ∼0.7 °C, astoundingly warmer than the record-length mean of 0.0 ± 0.2 °C, while low-flow year 2012 (∼0.8 Sv) is also remarkably cold (∼-0.6 °C), likely due to anomalously weak northward flow in January-March, partly driven by anomalously strong southward winds in March. A seasonal decomposition of properties of the main flow shows significant freshening in winter (∼0.03 psu/yr, January-March) likely due to sea-ice changes, but no trend (or perhaps salinization) in the rest of the year. A seasonal warming trend in the strait proper in May and June (∼0.04 °C/yr) is reflected in a trend to earlier arrival (0.9 ± 0.8 days/yr) of waters warmer than 0 °C. Contrastingly, no significant trend is found in the time of cooling of the strait. The strait's seasonal increasing transport trends (∼0.02 Sv/yr) are largest from May-November, likely due to the large wind-driven variability masking the signal in other months. We show that Ekman set-up of waters along the coast in the strait can explain the strong correlation of the water velocity with along-strait winds (as opposed to across-strait winds). We highlight the strong seasonality of this relationship (r ∼ 0.8 in winter, but only ∼0.4 in summer), which reflects the weak influence of the (seasonally weak) winds in summer. By separating the flow into portions driven by (a) the local wind and (b) a far-field (Pacific-Arctic "pressure-head") forcing, we find the increase in the Bering Strait throughflow is primarily due to a strong increase in the far-field forcing, not changes in the wind. We propose a higher annual mean transport for the strait for the 2000s, (1.0 ± 0.05 Sv) based on recent flow increases, and present estimated seasonal climatologies for properties and fluxes for the strait and for the ACC. Heat and freshwater seasonalities are strongly influenced by the ACC and stratification. Finally we conclude that year-round in situ mooring are still the only currently viable way of obtaining accurate quantifications of the properties of the Pacific input to the Arctic.
Genetic and Environmental Stability Differs in Reactive and Proactive Aggression
Tuvblad, Catherine; Raine, Adrian; Zheng, Mo; Baker, Laura A.
2009-01-01
The aim of this study was to examine stability and change in genetic and environmental influences on reactive (impulsive and affective) and proactive (planned and instrumental) aggression from childhood to early adolescence. The sample was drawn from an ongoing longitudinal twin study of risk factors for antisocial behavior at the University of Southern California (USC). The twins were measured on two occasions: ages 9–10 years (N = 1,241) and 11–14 years (N = 874). Reactive and proactive aggressive behaviors were rated by parents. The stability in reactive aggression was due to genetic and nonshared environmental influences, whereas the continuity in proactive aggression was primarily genetically mediated. Change in both reactive and proactive aggression between the two occasions was mainly explained by nonshared environmental influences, although some evidence for new genetic variance at the second occasion was found for both forms of aggression. These results suggest that proactive and reactive aggression differ in their genetic and environmental stability, and provide further evidence for some distinction between reactive and proactive forms of aggression. PMID:19688841
Dependence of global radiation on cloudiness and surface albedo in Tartu, Estonia
NASA Astrophysics Data System (ADS)
Tooming, H.
The dependence of global and diffuse radiation on surface albedo due to multiple reflection of radiation between the surface and the atmosphere (base of clouds) is found on the basis of data obtained at the Tartu-Tõravere Actinometric Station over the period 1955-2000. It is found that the monthly totals of global radiation increase by up to 1.38-1.88 times, particularly in the winter half-year between November and March, when snow cover albedo may be high. A semi-empirical formula is derived for calculating with sufficient accuracy the monthly totals of global radiation, considering the amount of cloudiness and the surface albedo. In the time series of the monthly total by global radiation a downward trend occurs in winter months. A decrease in global radiation by up to 20% in the past 46 years can be explained primarily by a relatively high negative trend in the snow cover duration and surface albedo (up to -0.24). As a result, days are growing darker, a new phenomenon associated with climate change, which undoubtedly affects human mood to some extent.
Synthetic cannabinoids 2015: An update for pediatricians in clinical practice
Castellanos, Daniel; Gralnik, Leonard M
2016-01-01
Synthetic cannabinoids are a group of substances in the world of designer drugs that have become increasingly popular over the past few years. Synthetic cannabinoids are a chemically diverse group of compounds functionally similar to THC. Since first appearing on the world market a few years ago these compounds have evolved rapidly. Newer more potent analogues have been developed. Identifying youth who abuse these substances can be difficult. Newer forms of consumption have also evolved. These products are now manufactured in products that look like natural cannabis resin and in liquid cartridges used in electronic cigarettes. Synthetic cannabinoids appear to be associated with potentially dangerous health effects that are more severe than that of marijuana. Some synthetic cannabinoid compounds have been associated with serious physical consequences, such as, seizures, myocardial infarction and renal damage. In addition, psychoactive effects, such as aggression, confusion, anxiety and psychosis have also been reported. The diagnosis remains primarily clinical with toxicological confirmation difficult due to manufacturers constantly developing new analogues to avoid detection. Pediatricians are urged to familiarize themselves with these drugs and the typical presentations of patients who use them. PMID:26862498
DOE Office of Scientific and Technical Information (OSTI.GOV)
Helali, A.N.; Jafolla, A.K.; Oumsiych, M.B.
1994-09-01
A 10-year-old white male presented with mild microcephaly, slight growth and psychomotor retardation, soft fleshy ears, and normal facial features except for thin lips. No other significant anomalies were reported except for tethered cord discovered at age 8 years. The karyotype was found to be 46,XY,der(18)t(13;18)(q32;p11.32)pat. The mild phenotype appears to be primarily due to the duplication of 13q32{yields}qter. None of the cardinal features of trisomy 13 are found in cases of duplication of bands 13q22 to qter. This case shows that Patau syndrome phenotype does not originate by duplication of 13q32{yields}qter and may thus be restricted to 13q22 tomore » 13q32. The variability in phenotypes points to an alternative explanation to the classical one of additive and interactive gene effects. This model involves effects of changes in chromosome position in the interphase nucleus on gene expression.« less
An Interdisciplinary Study of the SARS Virus: A One-Semester First-Year Seminar
ERIC Educational Resources Information Center
Ealy, Julie; Dorward, Adrienne
2005-01-01
The rationale for the first-year seminar is to introduce freshmen to the university. The basic components of a first-year seminar are academic integrity, skill development, a sense of community, active and collaborative learning strategies, and technology. All freshmen must take a first-year seminar that consists primarily of freshmen, although…
Fostering Interdisciplinary Thinking through an International Development Case Study
ERIC Educational Resources Information Center
Ellett, Rachel L.; Esperanza, Jennifer; Phan, Diep
2016-01-01
Despite widespread acknowledgment of the importance of interdisciplinary pedagogy, disciplinary teaching remains the norm on most campuses, primarily due to cost and institutional constraints. Bridging the gap between literature on interdisciplinary teaching and active-learning techniques, this article describes an innovative and less costly…
Novel method to identify probiotic isolates against enteric foodborne pathogens
USDA-ARS?s Scientific Manuscript database
Campylobacter is the leading cause of foodborne illness worldwide, primarily caused by consumption of contaminated poultry products. One potential strategy to reduce Campylobacter colonization in poultry is by the use of oral probiotics, but this produces variable results, possibly due to destructio...
Highway Safety Data : costs, quality, and strategies for improvement : final report
DOT National Transportation Integrated Search
1978-05-01
The objective of the experiment is to establish the influence of various types of trucks, buses and recreational vehicles on traffic flow on rural non-controlled access highways. This influence is due primarily to the low speeds which are common for ...
ERIC Educational Resources Information Center
McClung, Merle
1974-01-01
Since 1954 school children have sought and secured constitutional protection -- primarily under the First Amendment and the due process and equal protection clauses of the Fourteenth Amendment. Outlines some of the constitutional developments and recurring issues in education under (1) exclusion, (2) functional exclusion, (3) free expression, (4)…
Curative control of the peachtree borer using entomopathogenic nematodes
USDA-ARS?s Scientific Manuscript database
The peachtree borer, Synanthedon exitiosa, is a major pest of stone fruit trees in North America. Current management relies upon preventative control using broad spectrum chemical insecticides, primarily chlorpyrifos, applied in the late summer or early fall. However, due to missed applications, p...
DIETARY INTAKE OF PBDES BASED ON CONSUMPTION OF CATFISH IN SOUTHERN MISSISSIPPI
Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide variety of consumer products. Concerns surrounding these compounds are primarily due to their ubiquitous presence in the environment as well as human tissues, coupled with evidence indicating the poten...
Doroudi, Maryam; Schoen, Robert E; Pinsky, Paul F
2017-12-15
Screening for colorectal cancer (CRC) with flexible sigmoidoscopy (FS) has been shown to reduce CRC mortality. The current study examined whether the observed mortality reduction was due primarily to the prevention of incident CRC via removal of adenomatous polyps or to the early detection of cancer and improved survival. The Prostate, Lung, Colorectal, and Ovarian (PLCO) cancer screening trial randomized 154,900 men and women aged 55 to 74 years. Individuals underwent FS screening at baseline and at 3 or 5 years versus usual care. CRC-specific survival was analyzed using Kaplan-Meier curves and proportional hazards modeling. The authors estimated the percentage of CRC deaths averted by early detection versus primary prevention using a model that applied intervention arm survival rates to CRC cases in the usual-care arm and vice versa. A total of 1008 cases of CRC in the intervention arm and 1291 cases of CRC in the usual-care arm were observed. Through 13 years of follow-up, there was no significant difference noted between the trial arms with regard to CRC-specific survival for all CRC (68% in the intervention arm vs 65% in the usual-care arm; P =.16) or proximal CRC (68% vs 62%, respectively; P = .11) cases; however, survival in distal CRC cases was found to be higher in the intervention arm compared with the usual-care arm (77% vs 66%; P<.0001). Within each arm, symptom-detected cases had significantly worse survival compared with screen-detected cases. Overall, approximately 29% to 35% of averted CRC deaths were estimated to be due to early detection and 65% to 71% were estimated to be due to primary prevention. CRC-specific survival was similar across arms in the PLCO trial, suggesting a limited role for early detection in preventing CRC deaths. Modeling suggested that approximately two-thirds of avoided deaths were due to primary prevention. Future CRC screening guidelines should emphasize primary prevention via the identification and removal of precursor lesions. Cancer 2017;123:4815-22. © 2017 American Cancer Society. © 2017 American Cancer Society.
Injuries associated with police use of force.
Bozeman, William P; Stopyra, Jason P; Klinger, David A; Martin, Brian P; Graham, Derrel D; Johnson, James C; Mahoney-Tesoriero, Katherine; Vail, Sydney J
2018-03-01
Use of force [UOF] by police can result in serious injuries and fatalities. The risk of significant injuries associated with different force modalities is poorly defined. We sought to determine the incidence of police UOF and compare the likelihood of significant injury with different force modalities. A prospective multicenter observational study of all UOF incidents was conducted via mandatory UOF investigations at three mid-sized police agencies over a two year period. Expert physicians reviewed police and medical records to determine injury severity using a priori injury severity stratification criteria. There were 893 UOF incidents, representing a UOF rate of 0.086% of 1,041,737 calls for service (1 in 1167) and 0.78% of 114,064 criminal arrests(1 in 128). Suspects were primarily young (mean age, 31 years; range, 12-86 years) males (89%). The 1,399 force utilizations included unarmed physical force (n = 710, 51%), CEWs (504, 30%), chemical (88, 6.3%), canines (47, 3.4%), impact weapons (9, 0.6%), kinetic impact munitions (8, 0.6%), firearms (6, 0.4%), and other (27, 1.9%). Among 914 suspects, 898 (98%) sustained no or mild injury after police UOF. Significant (moderate or severe) injuries occurred in 16 (1.8%) subjects. Logistic regression analysis shows these are most associated with firearm and canine use. There was one fatality (0.1%) due to gunshots. No significant injuries occurred among 504 CEW uses (0%; 95% confidence interval, 0.0-0.9%). Of the 355 suspects transported to a medical facility, 78 (22%) were hospitalized. The majority of hospitalizations were unrelated to UOF (n = 59, 76%), whereas a minority (n = 19, 24%) were due to injuries related to police UOF. Police UOF is rare. When force is used officers most commonly rely on unarmed physical force and CEWs. Significant injuries are rare. Transport for medical evaluation is a poor surrogate for significant injury due to UOF. Epidemiological, level II.
Instability of the Present LEO Satellite Populations
NASA Technical Reports Server (NTRS)
Liou, Jer-Chyi; Johnson, Nicholas L.
2006-01-01
Several studies conducted during 1991-2001 demonstrated, with some assumed launch rates, the future unintended growth potential of the Earth satellite population, resulting from random, accidental collisions among resident space objects. In some low Earth orbit (LEO) altitude regimes where the number density of satellites is above a critical spatial density, the production rate of new breakup debris due to collisions would exceed the loss of objects due to orbital decay. A new study has been conducted in the Orbital Debris Program Office at the NASA Lyndon B. Johnson Space Center, using higher fidelity models to evaluate the current debris environment. The study assumed no satellites were launched after December 2005. A total of 150 Monte Carlo runs were carried out and analyzed. Each Monte Carlo run simulated the current debris environment and projected it 200 years into the future. The results indicate that the LEO debris environment has reached a point such that even if no further space launches were conducted, the Earth satellite population would remain relatively constant for only the next 50 years or so. Beyond that, the debris population would begin to increase noticeably, due to the production of collisional debris. Detailed analysis shows that this growth is primarily driven by high collision activities around 900 to 1000 km altitude - the region which has a very high concentration of debris at present. In reality, the satellite population growth in LEO will undoubtedly be worse than this study indicates, since spacecraft and their orbital stages will continue to be launched into space. Postmission disposal of vehicles (e.g., limiting postmission orbital lifetimes to less than 25 years) will help, but will be insufficient to constrain the Earth satellite population. To preserve better the near-Earth environment for future space activities, it might be necessary to remove existing large and massive objects from regions where high collision activities are expected.
Skeletal muscle metabolism in hypokinetic rats
NASA Technical Reports Server (NTRS)
Tischler, M. E.
1984-01-01
Muscle growth, protein metabolism, and amino acid metabolism were studied in various groups of rats. Certain groups were adrenaliectomized; some rats were suspended while others (the controls) were weight bearing. Results show that: (1) metabolic changes in the extensor digitorum longus muscle of suspended rats are due primarily to increased circulating glucocorticoids; (2) metabolic changes in the soleus muscle due to higher steroid levels are probably potentiated by greater numbers of steroid receptors; and (3) not all metabolic responses of the soleus muscle to unloading are due to the elevated levels of glucocorticoids or the increased sensitivity of this muscle to these hormones.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Richins, W.D.; Snow, S.D.; Miller, G.K.
1995-12-01
Some motor operated valves now have higher torque switch settings due to regulatory requirements to ensure valve operability with appropriate margins at design basis conditions. Verifying operability with these settings imposes higher stem loads during periodic inservice testing. These higher test loads increase stresses in the various valve internal parts which may in turn increase the fatigue usage factors. This increased fatigue is judged to be a concern primarily in the valve disks, seats, yokes, stems, and stem nuts. Although the motor operators may also have significantly increased loading, they are being evaluated by the manufacturers and are beyond themore » scope of this study. Two gate valves representative of both relatively weak and strong valves commonly used in commercial nuclear applications were selected for fatigue analyses. Detailed dimensional and test data were available for both valves from previous studies at the Idaho National Engineering Laboratory. Finite element models were developed to estimate maximum stresses in the internal parts of the valves and to identity the critical areas within the valves where fatigue may be a concern. Loads were estimated using industry standard equations for calculating torque switch settings prior and subsequent to the testing requirements of USNRC Generic Letter 89--10. Test data were used to determine both; (1) the overshoot load between torque switch trip and final seating of the disk during valve closing and (2) the stem thrust required to open the valves. The ranges of peak stresses thus determined were then used to estimate the increase in the fatigue usage factors due to the higher stem thrust loads. The usages that would be accumulated by 100 base cycles plus one or eight test cycles per year over 40 and 60 years of operation were calculated.« less
Obesity and injury-related absenteeism in a population-based firefighter cohort.
Poston, Walker S C; Jitnarin, Nattinee; Haddock, C Keith; Jahnke, Sara A; Tuley, Brianne C
2011-10-01
A consistent relationship has been demonstrated between obesity and absenteeism in the workplace. However, most studies have focused on primarily sedentary occupational groups. Firefighting is a physically demanding profession that involves significant potential for exposure to dangerous situations and strenuous work. No studies to date have evaluated the impact of obesity on risk for absenteeism among firefighters. We examined the cross-sectional association between BMI and obesity and injury-related absenteeism. BMI, body fat percentage (BF%), waist circumference (WC), injury, and injury-related absenteeism were assessed in 478 career male firefighters. One hundred and fifteen firefighters reported an injury in the previous year and the number of days absent from work due to their injury. BMI was an independent predictor of absenteeism due to injury even after adjustment for confounding variables. Firefighters meeting the definition of class II and III obesity had nearly five times (odds ratio (OR) = 4.89; 95% confidence interval (CI) = 3.63-6.58) the number missed work days due to injury when compared to their normal weight counterparts and their elevated risk was greater than firefighters with class I obesity (OR = 2.71; 95% CI = 2.01-3.65) or those who were overweight (OR = 2.55; 95% CI = 1.90-3.41). The attributable per capita costs of class II and III obesity-related absenteeism over the last year were $1,682.90 per firefighter, $254.00 per firefighter for class I obesity, and $74.41 per firefighter for overweight. Our findings suggest that class II and III obesity were associated with substantial attributable costs to employers and our cost estimates probably underestimate the actual financial burden.
Obesity and Injury-Related Absenteeism in a Population-Based Firefighter Cohort
Poston, Walker S.C.; Jitnarin, Nattinee; Haddock, C. Keith; Jahnke, Sara A.; Tuley, Brianne C.
2018-01-01
A consistent relationship has been demonstrated between obesity and absenteeism in the workplace. However, most studies have focused on primarily sedentary occupational groups. Firefighting is a physically demanding profession that involves significant potential for exposure to dangerous situations and strenuous work. No studies to date have evaluated the impact of obesity on risk for absenteeism among firefighters. We examined the cross-sectional association between BMI and obesity and injury-related absenteeism. BMI, body fat percentage (BF%), waist circumference (WC), injury, and injury-related absenteeism were assessed in 478 career male firefighters. One hundred and fifteen firefighters reported an injury in the previous year and the number of days absent from work due to their injury. BMI was an independent predictor of absenteeism due to injury even after adjustment for confounding variables. Firefighters meeting the definition of class II and III obesity had nearly five times (odds ratio (OR) = 4.89; 95% confidence interval (CI) = 3.63–6.58) the number missed work days due to injury when compared to their normal weight counterparts and their elevated risk was greater than firefighters with class I obesity (OR = 2.71; 95% CI = 2.01–3.65) or those who were overweight (OR = 2.55; 95% CI = 1.90–3.41). The attributable per capita costs of class II and III obesity-related absenteeism over the last year were $1,682.90 per firefighter, $254.00 per firefighter for class I obesity, and $74.41 per firefighter for overweight. Our findings suggest that class II and III obesity were associated with substantial attributable costs to employers and our cost estimates probably underestimate the actual financial burden. PMID:21633400
Chesapeake Bay Low Freshwater Inflow Study. Biota Assessment. Phase II. Main Report.
1982-05-01
organisms in shallow water with a sensitive life stage occurring in the spring of the year. This indicates that aquatic vegetation and sessile animals are...variety of animals, primarily waterfowl and aquatic mammals, although the fresh water marsh species are primarily used directly. The major pathway through...of the diverse freshwater /oligohaline SAV community, all of which would be *: similarly impacted by fresh water inflow reductions. In addition, input
Opportunities for Student Development in Two-Year Colleges. Monograph Series, Volume 6.
ERIC Educational Resources Information Center
Creamer, Don G., Ed.; Dassance, Charles R., Ed.
This monograph, addressed primarily to the concerns of practitioners, was written mostly by two-year college practitioners. Chapter 1, "Opportunities in Legacy" (Charles R. Dassance), discusses qualities of the two-year college, its special commitment to guidance of students, and its commitment to teaching as a primary thrust of educational…
Field Testing Of An Expert Model: Can The Model Predict Habitat Potential For Saltmarsh Birds?
Salt marshes are valuable resources, which provide numerous ecosystem services, including flood protection, fish nursery habitat, and nesting habitat for a number of threatened and endangered species. At the present time, due primarily to coastal development and sea level rise,...
Military Transformation: Intelligence, Surveillance and Reconnaissance
2003-01-17
http:// ww2 .pstripes.osd.mil/01/research1.html]. The Air Force is the largest military provider of surveillance and reconnaissance as it operates most... Infrared System both had funding requests reduced. The cuts were due primarily to seriously escalating costs and program management issues.101 The DOD
Assessment of the DoD Establishment of the Office of Security Cooperation -- Iraq
2012-03-16
a notable shortage of experienced foreign area officers, and • difficulty coordinating travel within Iraq, primarily due to the security situation...and assists in preparing for the receipt of medical team staff to conduct their training and exercises. Additionally, military veterinarians can
38 CFR 4.40 - Functional loss.
Code of Federal Regulations, 2011 CFR
2011-07-01
... DISABILITIES Disability Ratings The Musculoskeletal System § 4.40 Functional loss. Disability of the musculoskeletal system is primarily the inability, due to damage or infection in parts of the system, to perform... absence of part, or all, of the necessary bones, joints and muscles, or associated structures, or to...
38 CFR 4.40 - Functional loss.
Code of Federal Regulations, 2014 CFR
2014-07-01
... DISABILITIES Disability Ratings The Musculoskeletal System § 4.40 Functional loss. Disability of the musculoskeletal system is primarily the inability, due to damage or infection in parts of the system, to perform... absence of part, or all, of the necessary bones, joints and muscles, or associated structures, or to...
38 CFR 4.40 - Functional loss.
Code of Federal Regulations, 2013 CFR
2013-07-01
... DISABILITIES Disability Ratings The Musculoskeletal System § 4.40 Functional loss. Disability of the musculoskeletal system is primarily the inability, due to damage or infection in parts of the system, to perform... absence of part, or all, of the necessary bones, joints and muscles, or associated structures, or to...
38 CFR 4.40 - Functional loss.
Code of Federal Regulations, 2012 CFR
2012-07-01
... DISABILITIES Disability Ratings The Musculoskeletal System § 4.40 Functional loss. Disability of the musculoskeletal system is primarily the inability, due to damage or infection in parts of the system, to perform... absence of part, or all, of the necessary bones, joints and muscles, or associated structures, or to...
Validation of Fusarium Head Blight resistance QTL in US winter wheat
USDA-ARS?s Scientific Manuscript database
Fusarium head blight (FHB), primarily caused by Fusarium graminearum Schwabe [telemorph: Gibberella zeae Schw. (Petch)], can significantly reduce the grain quality of wheat (Triticum aestivum L.) due to mycotoxin contamination. Two US soft red winter wheat cultivars, Bess and NC-Neuse, have moderate...
Validation of fusarium head blight resistance QTL in US winter wheat
USDA-ARS?s Scientific Manuscript database
Fusarium head blight (FHB), primarily caused by Fusarium graminearum Schwabe [telemorph: Gibberella zeae Schw. (Petch)], can significantly reduce the grain quality of wheat (Triticum aestivum L.) due to mycotoxin contamination. Two US soft red winter wheat cultivars, Bess and NC-Neuse, have moderate...
Nixon's Checkers: A Rhetoric-Communication Criticism.
ERIC Educational Resources Information Center
Kneupper, Charles W.; Mabry, Edward A.
Richard Nixon's "Checkers" speech, a response to charges brought against the "Nixon fund," was primarily an effort to explain the behavior of Eisenhower's 1952 presidential-campaign staff. The effectiveness of this speech was largely due to Nixon's self-disclosure within the context of the speech's narrative mode. In…
NASA Technical Reports Server (NTRS)
Jayaraman, Sumita
1999-01-01
The report presents the results of the data analyses of the DIRBE-COBE data set to study the structure of the zodiacal cloud in the near-infrared wavebands at 1.2, 2.2, and 3.4 microns. The cloud has been divided into two components which have been analyzed and studied separately. The annual variation of the flux in the smooth or low frequency component has been measured in all three bands and the presence of any asymmetries due to the Earth's resonant ring have been studied. The high frequency component which primarily consisted of the asteroidal dust bands. Extensive and careful co-addition was done to extract the central bands in all three wavebands. The ten-degree bands are present in the 1.2 and 2.2 microns but not in the 3.4 micron waveband.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moreira, Airton Mota, E-mail: motamoreira@gmail.com; Marques, Carlos Frederico Sparapan, E-mail: sparapanmarques@gmail.com; Antunes, Alberto Azoubel, E-mail: antunesuro@uol.com.br
Prostatic artery embolization (PAE) is an alternative treatment for benign prostatic hyperplasia. Complications are primarily related to non-target embolization. We report a case of ischemic rectitis in a 76-year-old man with significant lower urinary tract symptoms due to benign prostatic hyperplasia, probably related to nontarget embolization. Magnetic resonance imaging revealed an 85.5-g prostate and urodynamic studies confirmed Inferior vesical obstruction. PAE was performed bilaterally. During the first 3 days of follow-up, a small amount of blood mixed in the stool was observed. Colonoscopy identified rectal ulcers at day 4, which had then disappeared by day 16 post PAE without treatment.more » PAE is a safe, effective procedure with a low complication rate, but interventionalists should be aware of the risk of rectal nontarget embolization.« less
Cuestas, Giselle; Rodríguez, Verónica; Doormann, Flavia; Pringe, Alejandra; Bellia Munzón, Patricio; Bellia Munzón, Gastón; Ortega, Carlos; Álvarez, Rubén
2017-04-01
Wegener's granulomatosis is a necrotizing granulomatous vasculitis of autoimmune origin that primarily affects the upper and lower airways and kidneys. It is very rare in children and adolescents. When started at a young age it is often associated with subglottic stenosis. Subglottic stenosis is a potentially fatal manifestation of Wegener's granulomatosis. Its diagnosis requires a high index of suspicion since it might develop in the absence of other signs of activity. Occasionally, subglottic stenosis may present as the initial manifestation of the disease. Diagnosis is confirmed by endoscopic visualization of the lesion. The treatment is complex, and it often requires repeated interventions due to restenosis. We present a 13-year-old patient with subglottic stenosis secondary to Wegener's granulomatosis. We describe the clinical manifestations, diagnosis and treatment of this rare cause of respiratory distress in the pediatric population. Sociedad Argentina de Pediatría.
Selective mutism: a team approach to assessment and treatment in the school setting.
Ponzurick, Joan M
2012-02-01
The school nurse plays a pivotal role in the assessment and treatment of selective mutism (SM), a rare disorder found in elementary school children. Due to anxiety, children with SM do not speak in uncomfortable situations, primarily the school setting. Diagnosis of SM is often missed in the formative years because the child does speak at home. Early diagnosis and treatment provide the key to addressing this rare disorder. The school nurse plays a critical role as a member of the Instructional Support Team (IST). The school nurse, as team liaison, provides communication between parents, school staff, and medical personnel. School nurses make a difference by advocating for the child with SM and possessing the necessary knowledge to effectively intervene. This article discusses a team approach to the assessment and treatment of SM and the role of the school nurse in the school setting.
Clinical manifestations and diagnosis of acromegaly.
Lugo, Gloria; Pena, Lara; Cordido, Fernando
2012-01-01
Acromegaly and gigantism are due to excess GH production, usually as a result of a pituitary adenoma. The incidence of acromegaly is 5 cases per million per year and the prevalence is 60 cases per million. Clinical manifestations in each patient depend on the levels of GH and IGF-I, age, tumor size, and the delay in diagnosis. Manifestations of acromegaly are varied and include acral and soft tissue overgrowth, joint pain, diabetes mellitus, hypertension, and heart and respiratory failure. Acromegaly is a disabling disease that is associated with increased morbidity and reduced life expectancy. The diagnosis is based primarily on clinical features and confirmed by measuring GH levels after oral glucose loading and the estimation of IGF-I. It has been suggested that the rate of mortality in patients with acromegaly is correlated with the degree of control of GH. Adequately treated, the relative mortality risk can be markedly reduced towards normal.
Clinical Manifestations and Diagnosis of Acromegaly
Lugo, Gloria; Pena, Lara; Cordido, Fernando
2012-01-01
Acromegaly and gigantism are due to excess GH production, usually as a result of a pituitary adenoma. The incidence of acromegaly is 5 cases per million per year and the prevalence is 60 cases per million. Clinical manifestations in each patient depend on the levels of GH and IGF-I, age, tumor size, and the delay in diagnosis. Manifestations of acromegaly are varied and include acral and soft tissue overgrowth, joint pain, diabetes mellitus, hypertension, and heart and respiratory failure. Acromegaly is a disabling disease that is associated with increased morbidity and reduced life expectancy. The diagnosis is based primarily on clinical features and confirmed by measuring GH levels after oral glucose loading and the estimation of IGF-I. It has been suggested that the rate of mortality in patients with acromegaly is correlated with the degree of control of GH. Adequately treated, the relative mortality risk can be markedly reduced towards normal. PMID:22518126
Isene, Rune; Bernklev, Tomm; Høie, Ole; Langholz, Ebbe; Tsianos, Epameonondas; Stockbrügger, Reinhold; Odes, Selwyn; Småstuen, Milada; Moum, Bjørn
2014-07-01
Patients with inflammatory bowel disease (IBD) have proven an increased risk of venous thromboembolism (VTE), particularly when hospitalized. The estimate of the true risk varies considerably between studies, primarily due to differences in methodology. We set out to determine the incidence of VTE in a population-based European inception cohort. IBD patients were incepted into a cohort that was prospectively followed from the early 1990s to the early 2000s. A total of 1145 patients were followed for a total of 10,634 patient-years (p.y.). A total of 19 thromboembolic events were identified - 13 deep vein thrombosis and 6 with pulmonary embolism. The incidence rate of VTE was 1.8 per 1000 p.y. The risk of VTE was elevated in this IBD cohort but lower than previously reported. The highest risk was seen in hospitalized patients, but corticosteroids-requiring disease in outpatients also conferred some risk.
Education and Health: the Role of Cognitive Ability*
Bijwaard, Govert; Veenman, Justus
2015-01-01
We aim to disentangle the relative impact of (i) cognitive ability, and (ii) education on health and mortality using a structural equation model suggested by Conti et al. (2010). We extend their model by allowing for a duration dependent variable (mortality), and an ordinal educational variable. Data come from a Dutch cohort born between 1937 and 1941, including detailed measures of cognitive ability and family background in the final grade of primary school. The data are linked to the mortality register 1995–2011, such that we observe mortality between ages 55 and 75. The results suggest that at least half of the unconditional survival differences between educational groups are due to a ‘selection effect’, primarily on the basis of cognitive ability. Conditional survival differences across those having finished just primary school and those entering secondary education are still substantial, and amount to a 4 years gain in life expectancy, on average. PMID:25912224
Spacecraft Charging in Low Temperature Environments
NASA Technical Reports Server (NTRS)
Parker, Linda N.
2007-01-01
Spacecraft charging in plasma and radiation environments is a temperature dependent phenomenon due to the reduction of electrical conductivity in dielectric materials at low temperatures. Charging time constants are proportional to l/conductivity may become very large (on the order of days to years) at low temperatures and accumulation of charge densities in insulators in charging environments traditionally considered benign at ambient temperatures may be sufficient to produce charge densities and electric fields of concern in insulators at low temperatures. Low temperature charging is of interest because a number of spacecraft-primarily infrared astronomy and microwave cosmology observatories-are currently being design, built, and or operated at very cold temperatures on the order of 40K to 100K. This paper reviews the temperature dependence of spacecraft charging processes and material parameters important to charging as a function of temperature with an emphasis on low temperatures regimes.
Temperature preference as an indicator of the chronic toxicity of cupric ions to Mozambique Tilapia
DOE Office of Scientific and Technical Information (OSTI.GOV)
Welch, T.J.; Stauffer, J.R. Jr.; Morgan, R.P. II
1989-11-01
Evaluation of the effects of environmental contaminants on aquatic communities has focused primarily on acute bioassays. These bioassays provide rapid and reproducible concentration response curves based on death as an endpoint. In recent years, however, emphasis has shifted towards monitoring sublethal effects of toxicants. Temperature is an easily quantifiable parameter influencing both the behavior and survival of fishes. As poikilotherms, fish use behavioral responses to help regulate body temperature. Fish thermoregulatory behavior may be altered by various toxic substances. Some researchers found that a 24 hr exposure of sublethal concentrations of copper caused a significant decrease in preferred temperature ofmore » fathead minnows (Pimephales promelas), although the results were confounded due to variations in copper concentrations. In this study, the authors examined the feasibility of using acute temperature preference tests to assess the chronic toxicity of low concentrations of free cupric ions to Mozambique tilapia, Oreochromis mossambicus (Peters).« less
Temperature, Sowing and Harvest Dates, and Yield of Maize in the Southwestern US
NASA Astrophysics Data System (ADS)
Kafatos, M.; Stack, D.; Myoung, B.; Kim, S. H.; Kim, J.
2014-12-01
Since sowing date of maize is sensitive to climate variability and changes, it is of a practical importance to examine how sowing dates affect maize yields in various temperature regimes in the southwestern US. A 21-year (1991-2011) simulation of maize yield using Agricultural Production Systems sIMulator (APSIM) with observed meteorological forcing, shows that earlier sowing dates are favorable for higher yields primarily by increasing the length of growing season in cold mountaineous regions. In these regions, warmer conditions in the sowing period tend to advance the sowing date and then enhance yield. Over low-elevation warm regions, yields are less correlated with sowing dates and the length of growing season, perhaps because growing season temperatures are high enough for fast growth. Instead, in the warm regions, maize yields are sensitive to temperature variations during the late growing season due to adverse effects of extreme high temperature events on maize development.
Earth observational research using multistage EOS-like data
NASA Technical Reports Server (NTRS)
Johannsen, C. J.; Landgrebe, D. A.
1994-01-01
This grant was funded as a part of a program in which both research and educational impact were intended. Research work under this grant is directed at the understanding and use of future hyperspectral data such as that from imaging spectrometers. Specifically, the objectives of the work were: to prepare suitable means for analyzing data from sensors which have large numbers of spectral bands, to advance the fundamental understanding of the manner in which soils and vegetative materials reflect high spectral resolution optical wavelength radiation, and to maximize the impact of the results on the educational community. Over the life of the grant, the work has thus involved basic earth science research and information system technique understanding and development in a mutually supportive way. However, during the later years it became necessary to focus the work primarily on the first and last areas, due to a steadily decreasing level of effort.
Potential advantages of solar electric propulsion for outer planet orbiters.
NASA Technical Reports Server (NTRS)
Sauer, C. G.; Atkins, K. L.
1972-01-01
Past studies of solar electric propulsion for outer planet orbiters have generally emphasized the advantages of flight time reduction and payload increases. However, several subtle advantages exist, which may become important in an environment of increasingly difficult requirements as ways to extend current technology are sought. These advantages accrue primarily because of the inherent capability, unique to electric propulsion, to efficiently shape a trajectory while enroute. Stressed in this paper are: the ability to meet orbital constraints due to assumed radiation belts, science flexibility in a dual launch program, increased numbers of observational passes, and the lengthening of launch periods. These are examined for years representative of relatively easy and difficult ballistic missions. The results indicate that an early investment in solar electric technology will provide a strong performance foundation for a long range outer planet exploration program which evolves from current spacecraft technology.
The Hypersensitivity of Horses to Culicoides Bites in British Columbia
Anderson, Gail S.; Belton, Peter; Kleider, Nicholas
1988-01-01
Culicoides hypersensitivity is a chronic, recurrent, seasonal dermatitis of horses that has a worldwide distribution, but has only recently been reported in Canada. It is characterized by intense pruritus resulting in lesions associated with self-induced trauma. A survey of veterinarians and horse-owners in British Columbia showed no differences in susceptibility due to the sex, color, breed, or height of the horses. The prevalence of the disease in the 209 horses surveyed was 26%. Horses sharing the same pasture could be unaffected. The disease was reported primarily from southwestern British Columbia; it occurred between April and October and usually affected the ventral midline, mane, and tail. Horses were generally less than nine years old when the clinical signs first appeared ([unk]=5.9 yr). Culicoides hypersensitivity was common in the lineage of several affected horses, possibly indicating a genetic susceptibility. Most cases were severe enough to require veterinary attention and some horses were euthanized. PMID:17423117
A Case Report About Cluster-Tic Syndrome Due to Venous Compression of the Trigeminal Nerve.
de Coo, Ilse; van Dijk, J Marc C; Metzemaekers, Jan D M; Haan, Joost
2017-04-01
The term "cluster-tic syndrome" is used for the rare ipsilateral co-occurrence of attacks of cluster headache and trigeminal neuralgia. Medical treatment should combine treatment for cluster headache and trigeminal neuralgia, but is very often unsatisfactory. Here, we describe a 41-year-old woman diagnosed with cluster-tic syndrome who underwent microvascular decompression of the trigeminal nerve, primarily aimed at the "trigeminal neuralgia" part of her pain syndrome. After venous decompression of the trigeminal nerve both a decrease in trigeminal neuralgia and cluster headache attacks was seen. However, the headache did not disappear completely. Furthermore, she reported a decrease in pain intensity of the remaining cluster headache attacks. This case description suggests that venous vascular decompression in cluster-tic syndrome can be remarkably effective, both for trigeminal neuralgia and cluster headache. © 2016 American Headache Society.
Hagfish predatory behaviour and slime defence mechanism
Zintzen, Vincent; Roberts, Clive D.; Anderson, Marti J.; Stewart, Andrew L.; Struthers, Carl D.; Harvey, Euan S.
2011-01-01
Hagfishes (Myxinidae), a family of jawless marine pre-vertebrates, hold a unique evolutionary position, sharing a joint ancestor with the entire vertebrate lineage. They are thought to fulfil primarily the ecological niche of scavengers in the deep ocean. However, we present new footage from baited video cameras that captured images of hagfishes actively preying on other fish. Video images also revealed that hagfishes are able to choke their would-be predators with gill-clogging slime. This is the first time that predatory behaviour has been witnessed in this family, and also demonstrates the instantaneous effectiveness of hagfish slime to deter fish predators. These observations suggest that the functional adaptations and ecological role of hagfishes, past and present, might be far more diverse than previously assumed. We propose that the enduring success of this oldest extant family of fishes over 300 million years could largely be due to their unique combination of functional traits. PMID:22355648
Medium-density fibreboard and occupational asthma. A case series.
Burton, C; Bradshaw, L; Agius, R; Burge, S; Huggins, V; Fishwick, D
2011-08-01
Medium-density fibreboard (MDF) is a wood composite material, composed primarily of softwood, bonded with a synthetic formaldehyde-based resin. It is increasingly used, as it has various advantages over natural woods. Enquiry of the national reporting scheme data and three case reports were used to further the evidence base linking this exposure to occupational asthma (OA). From 1991 to 2007, 21 cases of occupational sensitization to MDF were reported to the UK voluntary reporting scheme, Surveillance of Work Related Occupational Respiratory Disease (SWORD): 18 reported as occupational asthma (OA) and 3 as occupational rhinitis. All workers were male, with a mean age of 48 years, working in education, furniture manufacturing or joinery among other employments. Whilst reporting scheme data identified relatively small numbers of cases of OA likely to be due to MDF, the evidence base supporting this link is generally lacking. The three cases presented, where OA was attributed to MDF exposure, add to this evidence.
Brachytherapy devices and methods employing americium-241
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gray, L. A.
1985-04-16
Sources and methods for radiation therapy, particularly brachytherapy, employing americium-241 (60 keV gamma emission and 433 year half-life) provide major advantages for radiotherapy, including simplified radiation protection, dose reduction to healthy tissue, increased dose to tumor, and improved dose distributions. A number of apparent drawbacks and unfavorable considerations including low gamma factor, high self-absorption, increased activity required and alpha-particle generation leading to helium gas pressure buildup and potential neutron contamination in the generated radiation are all effectively dealt with and overcome through recognition of subtle favorable factors unique to americium-241 among brachytherapy sources and through suitable constructional techniques. Due tomore » an additional amount of radiation, in the order of 50%, provided primarily to nearby regions as a result of Compton scatter in tissue and water, higher dose rates occur than would be predicted by conventional calculations.« less
NASA Astrophysics Data System (ADS)
van den Haute, P.
1984-11-01
Fission-track method dating of 27 apatite samples recovered from Precambrian intrusive rocks has yielded ages in the 75-423 million year range, which is noted to be younger than the ages of emplacement or metamorphism for these rocks according to other radiometric methods. On the basis of the regional geology and the length ratios of spontaneous-to-induced tracks for 18 of the 27 samples, it can be inferred that the fission-track ages are not mixed ages due to a recent thermal event, but rather that they date the last cooling history of the studied massifs. This last cooling is interpreted as primarily the result of a slow, epirogenetic uplift which affected the area during the major part of the Phanerozoic. In this way, the large age variations can be ascribed to differential cooling caused by regional epirogenetic uplift rate differences.
The Science and technology Behind Galileo - Europes GPS
NASA Astrophysics Data System (ADS)
Saaj, C.; Underwood, C. I.; Noakes, C.; Park, D. W. G.; Moore, T.
Over recent years, the public has become increasingly aware of the existence of global satellite positioning systems, such as the American Global Positioning System (GPS), for which the generic term is Global Navigation Satellite System (GNSS). This is primarily due to high-profile use in various military conflicts, the acceptance of the technology by the leisure market (hill walking, yachting, etc) and the rapid development of mass-market applications (such as in-vehicle navigation). However, the public is still largely unaware of how GNSS is currently being utilized by researchers across a wide range of scientific applications. The aim of this paper is to provide answers to public's basic questions on GNSS and thereby raise public awareness on the science and technology behind the nascent Galileo project; a European initiative to design, build and deploy a global satellite positioning system similar to the GPS.
Sonographic diagnosis of vesicouterine fistula.
Park, O-R; Kim, T-S; Kim, H-J
2003-07-01
Vesicouterine fistula is one of the least common types of urogenital fistula, accounting for only 1-4% of all cases. We report a case of vesicouterine fistula after vacuum delivery in a woman with a history of a previous Cesarean section. The 29-year-old woman was hospitalized due to continuous serosanguinous vaginal leakage and hematuria. Transvaginal sonography demonstrated the presence of a fistulous tract between the uterus and the bladder. Cystoscopy demonstrated a small opening in the posterior bladder wall and a cystogram revealed a fistulous tract between the posterior portion of the bladder and the uterine cavity. Since the patient could not tolerate her symptoms, we decided to close the fistulous tract surgically. The fistulous tract was excised and the bladder and uterus were closed primarily. The bladder was drained with a Foley catheter for 12 days and subsequent follow-up of the patient has demonstrated urinary continence. Copyright 2003 ISUOG. Published by John Wiley & Sons, Ltd.
[All-ceramic peripheral restorations: crowns and bridges].
Legros, Caroline; Vanheusden, Alain
2006-01-01
Over the last years, current technologies in dental ceramics are strongly improved, constantly producing new materials for the restoration of the single or plural teeth. Feldspathic porcelains fused to a cast metal substructure, the so-called "metal-ceramic crown," has been long time the gold standard; this is primarily due to their predictable long-term strength characteristics. All-ceramic systems are a focus of interest, because they offer aesthetic results that may be difficult to achieve with metal-ceramic systems. Nowadays, the new ceramics associate aesthetic and good mechanical qualities, biocompatibility, accurate marginal fit and low invasive preparations. Thanks to the diversification of all-ceram processes, materials properties and clinical situations are now the prime criteria which determine the practitioner's choice. In this article, we try to summarize different clinical concepts for peripheric all-ceram restoration, such as crowns and bridges used in a daily dental practice.
Sex differences in work-related traumatic brain injury due to assault.
Mollayeva, Tatyana; Mollayeva, Shirin; Lewko, John; Colantonio, Angela
2016-06-16
To examine the etiology, prevalence and severity of assault-precipitated work-related traumatic brain injury (wrTBI) in Ontario, Canada through a sex lens. Cross-sectional study using data abstracted from the Ontario Workplace Safety and Insurance Board (WSIB) claims files in 2004. Descriptive analyses were conducted to determine the distribution of worker/employment/incident characteristics. Workplace physical violence that resulted in a TBI accounted for 6.6% percent of all TBI injury claims. Female workers, primarily in the health care/social services sector, accounted for over half of all TBIs. Most workers were assaulted by consumers/clients. Forty five percent of injuries occurred among workers with less than 3 years of employment. This paper identifies profiles of workers and workplaces for targeted preventive efforts. Future studies are needed to further address risk factors by sex and outcomes, such as length of disability and health care cost.
Goldman, Dana; Lakdawalla, Darius; Gailey, Adam; Zheng, Yuhui
2011-01-01
In 1975, 50 year-old Americans could expect to live slightly longer than most of their Western European counterparts. By 2005, American life expectancy had fallen behind that of most Western European countries. We find that this growing longevity gap is primarily due to real declines in the health of near-elderly Americans, relative to their Western European peers. We use a microsimulation approach to project what US longevity would look like, if US health trends approximated those in Western Europe. The model implies that differences in health can explain most of the growing gap in remaining life expectancy. In addition, we quantify the public finance consequences of this deterioration in health. The model predicts that gradually moving American cohorts to the health status enjoyed by Western Europeans could save up to $1.1 trillion in discounted total health expenditures from 2004 to 2050. PMID:21719178
Michaud, Pierre-Carl; Goldman, Dana; Lakdawalla, Darius; Gailey, Adam; Zheng, Yuhui
2011-07-01
In 1975, 50-year-old Americans could expect to live slightly longer than most of their Western European counterparts. By 2005, American life expectancy had fallen behind that of most Western European countries. We find that this growing longevity gap is primarily due to real declines in the health of near-elderly Americans, relative to their Western European peers. We use a microsimulation approach to project what US longevity would look like, if US health trends approximated those in Western Europe. The model implies that differences in health can explain most of the growing gap in remaining life expectancy. In addition, we quantify the public finance consequences of this deterioration in health. The model predicts that gradually moving American cohorts to the health status enjoyed by Western Europeans could save up to $1.1 trillion in discounted total health expenditures from 2004 to 2050. Copyright © 2011 Elsevier Ltd. All rights reserved.
Invisibility, Difference, and Disparity: Alcohol and Substance Abuse on Two-Year College Campuses
ERIC Educational Resources Information Center
Eren, Colleen; Keeton, André
2015-01-01
The impact of alcohol and substance abuse on college students' behavior has become a ripe area of focus and research. However, interest and research has primarily been focused on traditional four- year college students. Thus, the four-year college experience is taken as the default against which two-year colleges are compared. Nearly 12 million…
Projection display technologies for the new millennium
NASA Astrophysics Data System (ADS)
Kahn, Frederic J.
2000-04-01
Although analog CRTs continue to enable most of the world's electronic projection displays such as US consumer rear projection televisions, discrete pixel (digital) active matrix LCD and DLP reflective mirror array projectors have rapidly created large nonconsumer markets--primarily for business. Recent advances in image quality, compactness and cost effectiveness of digital projectors have the potential to revolutionize major consumer and entertainment markets as well. Digital penetration of the mainstream consumer projection TV market will begin in the hear 2000. By 2005 digital projection HDTVs could take the major share of the consumer HDTV projection market. Digital projection is expected to dominate both the consumer HDTV and the cinema market by 2010, resulting in potential shipments for all projection markets exceeding 10 M units per year. Digital projection is improving at a rate 10X faster than analog CRT projectors and 5X faster than PDP flat panels. Continued rapid improvement of digital projection is expected due to its relative immaturity and due to the wide diversity of technological improvements being pursued. Key technology enablers are the imaging panels, light sources and micro-optics. Market shares of single panel projectors, MEMs panels, LCOS panels and low T p-Si TFT LCD panel variants are expected to increase.
Tics and other stereotyped movements as side effects of pharmacological treatment.
Madruga-Garrido, Marcos; Mir, Pablo
2013-01-01
Tics and other stereotyped abnormal movements can be seen as adverse effects of some pharmacologic drugs. Among these drugs, antipsychotics may provoke tardive syndromes after a chronic exposure, primarily in the case of typical antipsychotics. These syndromes include tardive tics, tardive dyskinesia, or tardive akathisia, which present with tics or stereotyped movements as a clinical phenomenon. Psychostimulants (mainly methylphenidate) have traditionally been associated with the appearance of tics due to the increased dopamine activity caused by stimulants. Nevertheless, in recent years, several studies have concluded not only that methylphenidate does not exacerbate or reactivate tics but also that tics can improve with its use in patients with associated attention deficit and hyperactivity disorder and tic disorder. Antiepileptic drugs, although infrequently, can also induce tics, with carbamazepine and lamotrigine described as tic inducers. Other antiepileptics, including levetiracetam and topiramate, have been proposed as a potential treatment for tic disorders due to a positive effect on tics, especially in those with associated epileptic disorder. Clinical and therapeutic approaches to tics and stereotyped movements after exposure to antipsychotics, stimulants, and antiepileptic drugs will be reviewed in this chapter. © 2013 Elsevier Inc. All rights reserved.
Simulated effects of nitrogen saturation the global carbon budget using the IBIS model
Lu, Xuehe; Jiang, Hong; Liu, Jinxun; Zhang, Xiuying; Jin, Jiaxin; Zhu, Qiuan; Zhang, Zhen; Peng, Changhui
2016-01-01
Over the past 100 years, human activity has greatly changed the rate of atmospheric N (nitrogen) deposition in terrestrial ecosystems, resulting in N saturation in some regions of the world. The contribution of N saturation to the global carbon budget remains uncertain due to the complicated nature of C-N (carbon-nitrogen) interactions and diverse geography. Although N deposition is included in most terrestrial ecosystem models, the effect of N saturation is frequently overlooked. In this study, the IBIS (Integrated BIosphere Simulator) was used to simulate the global-scale effects of N saturation during the period 1961–2009. The results of this model indicate that N saturation reduced global NPP (Net Primary Productivity) and NEP (Net Ecosystem Productivity) by 0.26 and 0.03 Pg C yr−1, respectively. The negative effects of N saturation on carbon sequestration occurred primarily in temperate forests and grasslands. In response to elevated CO2 levels, global N turnover slowed due to increased biomass growth, resulting in a decline in soil mineral N. These changes in N cycling reduced the impact of N saturation on the global carbon budget. However, elevated N deposition in certain regions may further alter N saturation and C-N coupling.
NASA Technical Reports Server (NTRS)
Wood, S. E.; Paige, D. A.
1993-01-01
Using a Leighton-Murray type diurnal and seasonal Mars thermal model, we found that it is possible to reproduce the seasonal variation in daily-averaged pressures (approximately 680-890 Pa) measured by Viking Lander 1 (VL1), during years without global dust storms, with a standard deviation of less than 5 Pa. In this simple model, surface CO2, frost condensation, and sublimation rates at each latitude are determined by the net effects of radiation, latent heat, and heat conduction in subsurface soil layers. An inherent assumption of our model is that the seasonal pressure variation is due entirely to the exchange of mass between the atmosphere and polar caps. However, the results of recent Mars GCM modeling have made it clear that there is a significant dynamical contribution to the seasonal pressure variation. This 'weather' component is primarily due to large-scale changes in atmospheric circulation, and its magnitude depends somewhat on the dust content of the atmosphere. The overall form of the theoretical weather component at the location of VL1, as calculated by the AMES GCM, remains the same over the typical range of Mars dust opacities.
A review of treatment strategies for hydrofluoric acid burns: current status and future prospects.
Wang, Xingang; Zhang, Yuanhai; Ni, Liangfang; You, Chuangang; Ye, Chunjiang; Jiang, Ruiming; Liu, Liping; Liu, Jia; Han, Chunmao
2014-12-01
Hydrofluoric acid (HF), a dangerous inorganic acid, can cause severe corrosive effects and systemic toxicity. HF enters the human body via where it contacts, such as skin and mucosa, alimentary and respiratory tracts, and ocular surfaces. In the recent years, the incidence of HF burn has tended to increase over time. The injury mechanism of HF is associated primarily with the massive absorption of HF and the release of hydrogen ions. Correct diagnosis and timely treatment are especially important for HF burns. The critical procedure to treat HF burn is to prevent on-going HF absorption, and block the progressive destruction caused by fluoride ions. Due to the distinct characteristics of HF burns, the topical treatment, as well as systemic support, has been emphasised. Whereas, management of patients with HF burns remains a great challenge in some situations. To date, there has been no widely accepted protocol for the rescue of HF burns, partly due to the diversity of HF burns. This paper overviews the current status and problems of treatment strategies for HF burns, for the purpose of promoting the future researches and improvement. Copyright © 2014 Elsevier Ltd and ISBI. All rights reserved.
[REASONS OF DELAYED DIAGNOSIS OF BLADDER TUBERCULOSIS].
Kul'chavenja, E V; Holtobin, D P
2015-01-01
The fourth, terminal, stage of bladder tuberculosis (BT) manifests itself in irreversible changes and requires surgical treatment. To identify the reasons for delayed diagnosis of this urogenital tuberculosis complication. Medical history of 26 urogenital tuberculosis patients with a complicated form of stage 4 BT, referred to the Novosibirsk TB Research Institute for reconstructive surgery were analysed. In 22 patients, bladder volume ranged from 55 to 100 ml, 4 patients previously underwent cystostomy due to extremely small bladder volume. Average duration of BT hidden in the guise of "urogenital infection" was 6.2 years. Patients were treated with norfloxacin (a total of 104 courses), ciprofloxacin (86 courses), amikacin (43 courses), nitroxoline (27 courses), third generation cephalosporins (32 courses), lomefloxacin (17 courses), levofloxacin (11 courses), Amoxicillin clavulanate (4 courses), ampicillin (2 courses). It was demonstrated that all cases of BT stage 4 were iatrogenic. Irreversible debilitating complications occurred due to suboptimal therapy, primarily due to administration of amikacin and fluoroquinolones for urogenital infections, which was tuberculosis in disguise. Absence of M. tuberculosis growth does not exclude tuberculosis; pathological specimens must be further examined at least by PCR. Interventional material must be mandatory examined histologically and stained by Ziehl-Neelsen method to identify M. tuberculosis. Effective and not masking tuberculosis, optimal therapy for urogenital infections includes fosfomycin, furazidin (nitrofurantoin), gentamicin, III generation cephalosporins (in outpatient settings dispersible form of efixime should be preferable).
Medical Surveillance Monthly Report (MSMR). Volume 18, Number 01, January 2011
2011-01-01
pressure, diabetes, sleep apnea ) (16%); disorders of joints/back (7%); and tobacco use (5%). Th e epidemic of obesity in the general U.S. population is...nearly one million deaths worldwide; most deaths were due to P . falciparum infections of young children.1 Malaria’s health and economic impacts are...malaria incidence among U.S. service members, primarily due to P . vivax infections acquired near the DMZ in Korea.4,5, 9-11 Since 2001, U.S. service
Three eyelid localized cutaneous anthrax cases.
Esmer, Oktay; Karadag, Remzi; Bilgili, Serap Gunes; Gultepe, Bilge; Bayramlar, Huseyin; Karadag, Ayse Serap
2014-12-01
Anthrax is primarily seen in the developing countries, but it can be a worldwide medical concern due to bioterrorism threats. Palpebral anthrax is a rare form of cutaneous anthrax. Untreated cutaneous anthrax can be lethal. Patients with palpebral anthrax can develop complications including cicatrisation and ectropion. Thus, anthrax should be considered in differential diagnosis for patients presenting with preseptal cellulitis in high-risk regions. Herein, we report three anthrax cases (with different age) involving eyelids that were cured without any complications due to early diagnosis and treatment.
Thirty-year solid waste generation forecast for facilities at SRS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-07-01
The information supplied by this 30-year solid waste forecast has been compiled as a source document to the Waste Management Environmental Impact Statement (WMEIS). The WMEIS will help to select a sitewide strategic approach to managing present and future Savannah River Site (SRS) waste generated from ongoing operations, environmental restoration (ER) activities, transition from nuclear production to other missions, and decontamination and decommissioning (D&D) programs. The EIS will support project-level decisions on the operation of specific treatment, storage, and disposal facilities within the near term (10 years or less). In addition, the EIS will provide a baseline for analysis ofmore » future waste management activities and a basis for the evaluation of the specific waste management alternatives. This 30-year solid waste forecast will be used as the initial basis for the EIS decision-making process. The Site generates and manages many types and categories of waste. With a few exceptions, waste types are divided into two broad groups-high-level waste and solid waste. High-level waste consists primarily of liquid radioactive waste, which is addressed in a separate forecast and is not discussed further in this document. The waste types discussed in this solid waste forecast are sanitary waste, hazardous waste, low-level mixed waste, low-level radioactive waste, and transuranic waste. As activities at SRS change from primarily production to primarily decontamination and decommissioning and environmental restoration, the volume of each waste s being managed will change significantly. This report acknowledges the changes in Site Missions when developing the 30-year solid waste forecast.« less
Seward, Adam M; Beale, Colin M; Gilbert, Lucy; Jones, T Hefin; Thomas, Robert J
2014-01-01
Many populations of migratory songbirds are declining or shifting in distribution. This is likely due to environmental changes that alter factors such as food availability that may have an impact on survival and/or breeding success. We tested the impact of experimentally supplemented food on the breeding success over three years of northern wheatears (Oenanthe oenanthe), a species in decline over much of Europe. The number of offspring fledged over the season was higher for food-supplemented birds than for control birds. The mechanisms for this effect were that food supplementation advanced breeding date, which, together with increased resources, allowed further breeding attempts. While food supplementation did not increase the clutch size, hatching success or number of chicks fledged per breeding attempt, it did increase chick size in one year of the study. The increased breeding success was greater for males than females; males could attempt to rear simultaneous broods with multiple females as well as attempting second broods, whereas females could only increase their breeding effort via second broods. Multiple brooding is rare in the study population, but this study demonstrates the potential for changes in food availability to affect wheatear breeding productivity, primarily via phenotypic flexibility in the number of breeding attempts. Our results have implications for our understanding of how wheatears may respond to natural changes in food availability due to climate changes or changes in habitat management.
Foredune morphodynamics and seasonal sediment budget patterns at Humboldt Bay, Arcata, California.
NASA Astrophysics Data System (ADS)
Rader, A. M.; Walker, I. J.; Pickart, A.; Bauer, B. O.; Hesp, P.
2017-12-01
Coastal dune erosion, rebuilding, and ecosystem restoration are examined along a dune barrier system at Humboldt Bay, Arcata California. The long-term evolution of the system indicates progradation in the north (up to +0.51 m a-1) with densely vegetated, tall and topographically simple foredunes and landward retreat in the south (up to -0.49 m a-1) with sparsely vegetated, hummocky foredunes and blowouts. Spatial-temporal patterns of change from seasonal bare-Earth models during the early stages of a dynamic restoration project indicate that, in the year following initial removal of invasive vegetation (May 2015 - September 2016), the foredune system experienced a net positive sediment budget (+0.54 m3 m-2) while net erosion occurred on the beach (-0.38 m3 m-2). Five years of cross-shore profiles show a seaward migration of the foredune crest (+0.15 m mo-1) during the same time period. However, net erosion of the beach occurred during winter (November 2015 - April 2016), due to high-water and wave run-up during intense storms. Summer monitoring reveals site-wide accretion due to beach rebuilding and increased aeolian activity. As such, seasonal sediment budgets may be controlled primarily by the amount of beach sediment available for aeolian transport and secondarily by localized vegetation zonation on the upper beach and foredune. Further monitoring of the dune barrier system at Humboldt Bay throughout the remaining dynamic restoration process will provide further insight into the role of vegetation zonation and foredune morphodynamics.
Seed reserves diluted during surface soil reclamation in eastern Mojave Desert
Scoles-Sciulla, S. J.; DeFalco, L.A.
2009-01-01
Surface soil reclamation is used to increase the re-establishment of native vegetation following disturbance through preservation and eventual replacement of the indigenous seed reserves. Employed widely in the mining industry, soil reclamation has had variable success in re-establishing native vegetation in arid and semi-arid regions. We tested whether variable success could be due in part to a decrease of seed reserves during the reclamation process by measuring the change in abundance of germinable seed when surface soil was mechanically collected, stored in a soil pile for 4 months, and reapplied upon completion of a roadway. Overall seed reserve declines amounted to 86% of the original germinable seed in the soil. The greatest decrease in seed reserves occurred during soil collection (79% of original reserves), compared to the storage and reapplication stages. At nearby sites where stored surface soil had been reapplied, no perennial plant cover occurred from 0.5 to 5 years after application and <1% cover after 7 years compared to 5% cover in nearby undisturbed areas. The reduction in abundance of germinable seed during reclamation was primarily due to dilution of seed reserves when deeper soil fractions without seed were mixed with the surface soil during collection. Unless more precise techniques of surface soil collection are utilized, soil reclamation alone as a means for preserving native seed reserves is a method ill-suited for revegetating disturbed soils with a shallow seed bank, such as those found in the Mojave Desert. Copyright ?? Taylor & Francis Group, LLC.
Report on Research at AFGL, January 1979-December 1980.
1982-04-01
Labora- tory. It covers a two-year interval. Although written primarily for Air Force and DOD managers of research and development it is intended to...also includes an introductory chap- ter on AFGL management and logistic activities related to the reporling period. DD IJAN73 1473 EDITIONO I NOV 6S IS...the Air Force Cambridge Research Laboratories (AFCRL). Written primarily for Air Force and DOD managers of research and devel- opment, it shows how
All washed out? Foliar nutrient resorption and leaching in senescing switchgrass
USDA-ARS?s Scientific Manuscript database
Ideal bioenergy feedstocks are low in nutrients that act as anti-quality factors during conversion processes. Research has shown that delaying harvest of temperate perennial grasses until late winter reduces nutrient content, primarily due to end-season resorption, but also indicates a role for foli...
USDA-ARS?s Scientific Manuscript database
Discrepancies can arise among surface flux measurements collected using disparate techniques due to differences in both the instrumentation and theoretical underpinnings of the different measurement methods. Using data collected primarily over a pair of irrigated cotton fields as a part of the Bushl...
Development of a D genome specific marker resource for diploid and hexaploid wheat
USDA-ARS?s Scientific Manuscript database
Mapping and map-based cloning of genes that control agriculturally and economically important traits remain great challenges for plants with complex highly repetitive genomes such as those of the grass tribe, Triticeae. Mapping limitations in the Triticeae are primarily due to low frequencies of po...
Novel use of lipid-producing bacteria to increase circulating triglycerides in swine
USDA-ARS?s Scientific Manuscript database
Weanling pigs are at a high risk of succumbing to illness primarily due to an insufficient supply of available energy, and therefore, a weakened immune system. Solutions have been presented to supplement feed with alternate energy sources, yet limitations still arise with the utilization of these so...
A framework to build scientific confidence in read across results. (SOT CE course presentation)
Read-across acceptance is remains a major hurdle primarily due to the lack of objectivity and clarity on how to practically address uncertainties. One avenue that can be exploited to build scientific confidence in the development and evaluation of read-across is by taking advant...
Sugar Beet, Energy Beet, and Industrial Beet
USDA-ARS?s Scientific Manuscript database
Sugar beet (Beta vulgaris) is a temperate root crop grown primarily as a source of sucrose for human diets. Breeding has focused on sucrose yield, which is simply the product of total root yield times the proportion of sucrose in the harvested roots, minus loss of sucrose in molasses due to impuriti...
The Intersectionality of Religious Belief and Sexual Identity
ERIC Educational Resources Information Center
Yadron, Christopher
2016-01-01
The potential for conflict or tension between the cultural variables of sexual identity and religious belief for counselors, clients, and counseling students is well-documented by the counseling literature. The tension has existed primarily due to competing religious values for counselors and clients most often with respect to the phenomena of…
Notes from North America: On the Road
ERIC Educational Resources Information Center
Alper, Paul
2010-01-01
The new objects of public and open prejudice are Hispanics, primarily Mexicans due to their large population and their proximity to the United States. Because the Iraq War is such a disaster on all fronts, conservatives and reactionaries have shifted their patriotic fervour from invading foreign countries to inveighing against brown-skinned…
Analysis of induction and establishment of dwarf bunt of wheat under marginal climatic conditions.
USDA-ARS?s Scientific Manuscript database
Dwarf bunt caused by Tilletia contraversa has limited distribution due to essential climatic requirements; primarily persistent snow cover. The pathogen is a quarantine organism in several countries outside of the USA, some of which may have marginal climate for the disease, including the People’s ...
Cultivating Bilingual Learners' Language Arts Knowledge: A Framework for Successful Teaching
ERIC Educational Resources Information Center
Almaguer, Isela; Esquierdo, J. Joy
2013-01-01
It is essential to support bilingual learners' language and academic development; however, teaching second language learners English has taken precedence over teaching content area knowledge and vocabulary, specifically for language arts. The focus has shifted from content area instruction to primarily second language instruction due to an…
Genetic analyses of anthocyanin concentrations and the intensity of red color in onion
USDA-ARS?s Scientific Manuscript database
Higher concentrations of anthocyanins in vegetables are important for attractive appearance and may offer health benefits for consumers. The red color of onion bulbs is due primarily to the accumulation of anthocyanins. Segregating haploid plants from the cross of yellow and red inbreds were asexual...
Sensitivity Analysis of SWAT Nitrogen Simulations with and without In-Stream Processes
Nitrogen (N) losses to surface waters are of great concern on both national and regional scales. Scientists have concluded that large areas of hypoxia in the northern Gulf of Mexico are due to excessive nutrients derived primarily from agricultural runoff via the Mississippi Rive...
Photosynthesis, growth and maize yields in the context of global change
USDA-ARS?s Scientific Manuscript database
Maize is the third most important grain crop behind wheat and rice. Global mean temperatures are rising primarily due to anthropogenic carbon dioxide emissions into the earth’s atmosphere. Warmer temperatures over major landmasses are predicted to alter precipitation patterns and to increase the f...
USDA-ARS?s Scientific Manuscript database
Pioneer studies on infectious disease and immunology by Jenner, Pasteur, Koch, Von Behring, Nocard, Roux, and Ehrlich forged a path for the dual-purpose with dual benefit approach, demonstrating a profound relevance of veterinary studies for biomedical applications. Tuberculosis (TB), primarily due ...
Applying Sustainable Systems Development Approach to Educational Technology Systems
ERIC Educational Resources Information Center
Huang, Albert
2012-01-01
Information technology (IT) is an essential part of modern education. The roles and contributions of technology to education have been thoroughly documented in academic and professional literature. Despite the benefits, the use of educational technology systems (ETS) also creates a significant impact on the environment, primarily due to energy…
High-Ability Women and Men in Undergraduate Mathematics and Chemistry Courses.
ERIC Educational Resources Information Center
Bali, John; And Others
1985-01-01
Using samples of college students of very high ability and strong academic background, sex differences in performance and perceptions of performance in introductory chemistry and mathematics courses were studied. Considerable differences favoring men were found, and these appeared to be due primarily to differences in mathematics background.…
DAILY INTAKE ESTIMATES OF PBDES ASSOCIATED WITH CONSUMPTION OF CATFISH IN THE U.S.
Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide variety of consumer products. Concerns surrounding these compounds are primarily due do their ubiquitous presence in the environment as well as in human tissue, such as milk, coupled with evidence indi...
Case Report: Emergence of bovine viral diarrhea virus persistently infected calves in a closed herd
USDA-ARS?s Scientific Manuscript database
Bovine viral diarrhea virus (BVDV) continues to have significant economic impact on the cattle industry worldwide. The virus is primarily maintained in the cattle population due to persistently infected animals. Herd surveillance along with good vaccination programs and biosecurity practices are the...
Performance of a logging truck with a central tire inflation system.
John A. Sturos; Douglas B. Brumm; Andrew Lehto
1995-01-01
Describes the performance of an 11-axle logging truck with a central tire inflation system. Results included reduced damages to roads, improved ride of the truck, improved drawbar pull, and reduced rolling resistance. Road construction costs were reduced 62%, primarily due to using 33% less gravel.
Impacts of habitat loss, climate change and pesticide exposure on kit fox populations
Background / Question / Methods The San Joaquin kit fox is an endangered sub-species in decline due primarily to loss of habitat. This small, desert-adapted fox was once widely distributed across the floor of the southern San Joaquin Valley, but agriculture and development have ...
Sanitary sewer overflows (SSOs) occur when untreated sewage is discharged into water sources potentially causing contamination. SSOs are primarily caused by heavy rainfall, which is expected to become heavier and more episodic due to climate change. We conducted a case-crossover ...
Viewing Agricultural Education Research through a Qualitative Lens
ERIC Educational Resources Information Center
Dooley, Kim E.
2007-01-01
The Journal of Agricultural Education has primarily published research that uses quantitative research methods. Perhaps this is due partly to the lack of a qualitative research conceptual framework to guide our profession. Most researchers in agricultural education were academically prepared to conduct empirical research. Those who are in the…
Personal Reflections of a First Lay President
ERIC Educational Resources Information Center
Doud, Jacqueline Powers
2014-01-01
While this article is not about women's colleges or exclusively women presidents, the author notes, it is women's colleges that have experienced the greatest challenges, due primarily to financial constraints and competition. As operational costs escalated and choices for students increased, many small struggling colleges with little or no…
B-52 and KC-135 Mission Qualification and Continuation Training: A review and Analysis
1991-08-01
physical resources for completing the training requirements. Training is developed, scheduled, verified, and tracked primarily by the unit DOT, in...experienced EWs to develop their programs. To date, standard academic materials to support them, such as coursebooks , have not been produced. Due to
Preventing Boredom in the Language Laboratory
ERIC Educational Resources Information Center
Obanya, Pai
1978-01-01
An experimental year of oral testing using the language laboratory at Victoria University is described. A new first-year 12-credit course is primarily a language course based on audiovisual/lingual methods. The content, evaluation, and administration of oral expression tests and performance tapes are covered. (SW)
Maiti, Raman; Cowie, Raelene M; Fisher, John; Jennings, Louise M
2017-01-01
Complications of patellofemoral arthroplasty often occur soon after implantation and, as well as other factors, can be due to the design of the implant or its surgical positioning. A number of studies have previously considered the wear of ultra-high-molecular-weight polyethylene patellae following suboptimal implantation; however, studies have primarily been carried out under a limited number of degrees of freedom. The aim of this study was to develop a protocol to assess the wear of patellae under a malaligned condition in a six-axis patellofemoral joint simulator. The malalignment protocol hindered the tracking of the patella centrally in the trochlear groove and imparted a constant 5° external rotation (tilt) on the patella button. Following 3 million cycles of wear simulation, this condition had no influence on the wear of ultra-high-molecular-weight polyethylene patellae aged for 4 years compared to well-positioned non-aged implants (p > 0.05). However, under the malaligned condition, ultra-high-molecular-weight polyethylene patellae aged 8–10 years after unpacking (following sterilisation by gamma irradiation in an inert atmosphere) and worn ultra-high-molecular-weight polyethylene components also aged 4 years after unpacking (following the same sterilisation process) exhibited a high rate of wear. Fatigue failure due to elevated contact stress led to delamination of the ultra-high-molecular-weight polyethylene and in some cases complete failure of the patellae. The results suggest that suboptimal tracking of the patella in the trochlear groove and tilt of the patella button could have a significant effect on the wear of ultra-high-molecular-weight polyethylene and could lead to implant failure. PMID:28661229
Maiti, Raman; Cowie, Raelene M; Fisher, John; Jennings, Louise M
2017-07-01
Complications of patellofemoral arthroplasty often occur soon after implantation and, as well as other factors, can be due to the design of the implant or its surgical positioning. A number of studies have previously considered the wear of ultra-high-molecular-weight polyethylene patellae following suboptimal implantation; however, studies have primarily been carried out under a limited number of degrees of freedom. The aim of this study was to develop a protocol to assess the wear of patellae under a malaligned condition in a six-axis patellofemoral joint simulator. The malalignment protocol hindered the tracking of the patella centrally in the trochlear groove and imparted a constant 5° external rotation (tilt) on the patella button. Following 3 million cycles of wear simulation, this condition had no influence on the wear of ultra-high-molecular-weight polyethylene patellae aged for 4 years compared to well-positioned non-aged implants (p > 0.05). However, under the malaligned condition, ultra-high-molecular-weight polyethylene patellae aged 8-10 years after unpacking (following sterilisation by gamma irradiation in an inert atmosphere) and worn ultra-high-molecular-weight polyethylene components also aged 4 years after unpacking (following the same sterilisation process) exhibited a high rate of wear. Fatigue failure due to elevated contact stress led to delamination of the ultra-high-molecular-weight polyethylene and in some cases complete failure of the patellae. The results suggest that suboptimal tracking of the patella in the trochlear groove and tilt of the patella button could have a significant effect on the wear of ultra-high-molecular-weight polyethylene and could lead to implant failure.
Waldrop, M.P.; Firestone, M.K.
2006-01-01
Soil microbial communities are closely associated with aboveground plant communities, with multiple potential drivers of this relationship. Plants can affect available soil carbon, temperature, and water content, which each have the potential to affect microbial community composition and function. These same variables change seasonally, and thus plant control on microbial community composition may be modulated or overshadowed by annual climatic patterns. We examined microbial community composition, C cycling processes, and environmental data in California annual grassland soils from beneath oak canopies and in open grassland areas to distinguish factors controlling microbial community composition and function seasonally and in association with the two plant overstory communities. Every 3 months for up to 2 years, we monitored microbial community composition using phospholipid fatty acid (PLFA) analysis, microbial biomass, respiration rates, microbial enzyme activities, and the activity of microbial groups using isotope labeling of PLFA biomarkers (13C-PLFA) . Distinct microbial communities were associated with oak canopy soils and open grassland soils and microbial communities displayed seasonal patterns from year to year. The effects of plant species and seasonal climate on microbial community composition were similar in magnitude. In this Mediterranean ecosystem, plant control of microbial community composition was primarily due to effects on soil water content, whereas the changes in microbial community composition seasonally appeared to be due, in large part, to soil temperature. Available soil carbon was not a significant control on microbial community composition. Microbial community composition (PLFA) and 13C-PLFA ordination values were strongly related to intra-annual variability in soil enzyme activities and soil respiration, but microbial biomass was not. In this Mediterranean climate, soil microclimate appeared to be the master variable controlling microbial community composition and function. ?? 2006 Springer Science+Business Media, Inc.
Challenging the First Year of College: Old Models and New Imperatives
ERIC Educational Resources Information Center
Mills, Shala A.; Mehaffy, George L.
2016-01-01
This chapter argues that the first year of college needs to be reconsidered. The authors offer, as an alternative, a new kind of course, one created by groups of faculty members from different campuses, multidisciplinary in focus, delivered in a blended format, focused on civic outcomes, and intended primarily for first-year students.
Avian guild structure and habitat associations in suburban bird communities
Richard M. DeGraaf; James M. Wentworth
1986-01-01
Breeding bird communities were compared in three suburbs: a 70-year-old area of large houses along streets shaded by mature trees (MT), primarily oaks (Quercus) and elms (Ulmus); a 15-year-old area built upon open agricultural land with young maple (Acer) street trees (YT); and a 15-year-old area on which...
Bills, Bruce G.; James, Thomas S.; Mengel, John G.
1999-01-01
Precessional motion of Earth's rotation axis relative to its orbit is a well-known source of long-period climatic variation. It is less well appreciated that growth and decay of polar ice sheets perturb the symmetry of the global mass distribution enough that the geographic location of the rotation axis will change by at least 15 km and possibly as much as 100 km during a single glacial cycle. This motion of the pole will change the seasonal and latitudinal pattern of temperatures. We present calculations, based on a diurnal average energy balance, which compare the summer and winter temperature anomalies due to a 1° decrease in obliquity with those due to a 1° motion of the rotation pole toward Hudson Bay. Both effects result in peak temperature perturbations of about 1° Celsius. The obliquity change primarily influences the amplitude of the seasonal cycle, while the polar motion primarily changes the annual mean temperatures. The polar motion induced temperature anomaly is such that it will act as a powerful negative feedback on ice sheet growth. We also explore the evolution of the coupled system composed of ice sheet mass and pole position. Oscillatory solutions result from the conflicting constraints of rotational and thermal stability. A positive mass anomaly on an otherwise featureless Earth is in rotational equilibrium only at the poles or the equator. The two polar equilibria are rotationally unstable, and the equatorial equilibrium, though rotationally stable, is thermally unstable. We find that with a plausible choice for the strength of coupling between the thermal and rotational systems, relatively modest external forcing can produce significant response at periods of 104–106 years, but it strongly attenuates polar motion at longer periods. We suggest that these coupled oscillations may contribute to the observed dominance of 100 kyr glacial cycles since the mid-Pleistocene and will tend to stabilize geographic patterns that are suitable to glaciations.
NASA Astrophysics Data System (ADS)
Flores, R. P.; Rijnsburger, S.; Horner-Devine, A.; Souza, A. J.; Pietrzak, J.
2016-02-01
This work will describe dominant processes affecting suspended sediment transport along the Dutch coast, in the mid-field plume region of the Rhine River. We will present field observations from two long-term deployments conducted in the vicinity of the Sand Engine, a mega-nourishment experiment located 10 km north of the Rhine river mouth. To investigate the role of density stratification, winds, tides, waves and river plume processes on sediment transport, frames and moorings were deployed within the excursion of the tidal plume front generated by the freshwater outflow from the Rhine River for 4 and 6 weeks during years 2013 and 2014, respectively. The moorings were designed to measure vertical profiles of suspended sediment concentration (SSC) and salinity, using arrays of CTDs and OBS sensors. Mean tidal velocities were measured using bottom-mounted ADCPs. The near-bed dynamics and the near-bottom sediment concentrations were measured as well using a set of synchronized ADVs and OBSs. By combining the two deployments we observe hydrodynamics and suspended sediment dynamics under a wide range of forcing conditions. Preliminary observations indicate that stratification is highly dependent on wind magnitude and direction, and its role is primarily identified as to induce significant cross-shore sediment transport product of the generation of cross-shore velocities due to the modification of the tidal ellipses and the passage of the surface plume front. The passage of the surface plume front generates strong offshore currents near the bottom, producing transport events that can be similar in magnitude to the dominant alongshore transport. Preliminary results also indicate that storms play an important role in alongshore transport primarily by wave-induced sediment resuspension, but as stratification is suppressed due to the enhancement of mixing processes, no significant cross-shore transport is observed during very energetic conditions.
The pharmacology and toxicology of kratom: from traditional herb to drug of abuse.
Warner, Marcus L; Kaufman, Nellie C; Grundmann, Oliver
2016-01-01
Mitragyna speciosa (Rubiaceae), commonly known as kratom, is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. In recent years, kratom has gained popularity for use as a recreational drug across the globe. Relatively new to the illicit market and used in a manner different from its traditional applications, preparations of kratom are touted by many as a safe and legal psychoactive product that improves mood, relieves pain, and may provide benefits in opiate addiction. Available literature was reviewed for M. speciosa via PubMed, Google Scholar, CINAHL, and EBSCO to summarize its traditional uses, phytochemical composition, pharmacology and toxicology of proposed active constituents, and potential for misuse and abuse. Research has demonstrated that both stimulant and sedative dose-dependent effects do exist, but a growing concern for the drug's effects and safety of use has resulted in national and international attention primarily due to an increase in hospital visits and deaths in several countries that are said to have been caused by extracts of the plant. The main active alkaloid substances in kratom, mitragynine and 7-hydroxymitragynine, present with a range of CNS stimulant and depressant effects mediated primarily through monoaminergic and opioid receptors. Recently, Palm Beach County, located in the southeastern corridor of Florida, has considered regulating kratom due to public safety concerns following the death of a young adult. At the local, state, and even federal levels, governments are now being confronted with the task of determining the safety and the possible regulation of kratom extracts. There are currently no standard analytical screening techniques for mitragynine and its metabolites following ingestion limiting its detection to more sophisticated techniques like liquid chromatography-mass spectrometry to determine kratom use. The growing concern of the abuse potential of kratom requires careful evaluation of its benefits and potential toxicities.
Cassini Ion Mass Spectrometer Peak Calibrations from Statistical Analysis of Flight Data
NASA Astrophysics Data System (ADS)
Woodson, A. K.; Johnson, R. E.
2017-12-01
The Cassini Ion Mass Spectrometer (IMS) is an actuating time-of-flight (TOF) instrument capable of resolving ion mass, energy, and trajectory over a field of view that captures nearly the entire sky. One of three instruments composing the Cassini Plasma Spectrometer, IMS sampled plasma throughout the Kronian magnetosphere from 2004 through 2012 when it was permanently disabled due to an electrical malfunction. Initial calibration of the flight instrument at Southwest Research Institute (SwRI) was limited to a handful of ions and energies due to time constraints, with only about 30% of planned measurements carried out prior to launch. Further calibration measurements were subsequently carried out after launch at SwRI and Goddard Space Flight Center using the instrument prototype and engineering model, respectively. However, logistical differences among the three calibration efforts raise doubts as to how accurately the post-launch calibrations describe the behavior of the flight instrument. Indeed, derived peak parameters for some ion species differ significantly from one calibration to the next. In this study we instead perform a statistical analysis on 8 years of flight data in order to extract ion peak parameters that depend only on the response of the flight instrument itself. This is accomplished by first sorting the TOF spectra based on their apparent compositional similarities (e.g. primarily water group ions, primarily hydrocarbon ions, etc.) and normalizing each spectrum. The sorted, normalized data are then binned according to TOF, energy, and counts in order to generate energy-dependent probability density maps of each ion peak contour. Finally, by using these density maps to constrain a stochastic peak fitting algorithm we extract confidence intervals for the model parameters associated with various measured ion peaks, establishing a logistics-independent calibration of the body of IMS data gathered over the course of the Cassini mission.
Dinsmore, K J; Billett, M F; Dyson, K E
2013-07-01
The aquatic pathway is increasingly being recognized as an important component of catchment carbon and greenhouse gas (GHG) budgets, particularly in peatland systems due to their large carbon store and strong hydrological connectivity. In this study, we present a complete 5-year data set of all aquatic carbon and GHG species from an ombrotrophic Scottish peatland. Measured species include particulate and dissolved forms of organic carbon (POC, DOC), dissolved inorganic carbon (DIC), CO2 , CH4 and N2 O. We show that short-term variability in concentrations exists across all species and this is strongly linked to discharge. Seasonal cyclicity was only evident in DOC, CO2 and CH4 concentration; however, temperature correlated with monthly means in all species except DIC. Although the temperature correlation with monthly DOC and POC concentrations appeared to be related to biological productivity in the terrestrial system, we suggest the temperature correlation with CO2 and CH4 was primarily due to in-stream temperature-dependent solubility. Interannual variability in total aquatic carbon concentration was strongly correlated with catchment gross primary productivity (GPP) indicating a strong potential terrestrial aquatic linkage. DOC represented the largest aquatic carbon flux term (19.3 ± 4.59 g C m(-2) yr(-1) ), followed by CO2 evasion (10.0 g C m(-2) yr(-1) ). Despite an estimated contribution to the total aquatic carbon flux of between 8 and 48%, evasion estimates had the greatest uncertainty. Interannual variability in total aquatic carbon export was low in comparison with variability in terrestrial biosphere-atmosphere exchange, and could be explained primarily by temperature and precipitation. Our results therefore suggest that climatic change is likely to have a significant impact on annual carbon losses through the aquatic pathway, and as such, aquatic exports are fundamental to the understanding of whole catchment responses to climate change. © 2013 Blackwell Publishing Ltd.
Oki, Ryo; Ito, Kazuto; Suzuki, Rie; Fujizuka, Yuji; Arai, Seiji; Miyazawa, Yoshiyuki; Sekine, Yoshitaka; Koike, Hidekazu; Matsui, Hiroshi; Shibata, Yasuhiro; Suzuki, Kazuhiro
2018-04-26
Japan has experienced a drastic increase in the incidence of prostate cancer (PC). To assess changes in the risk for PC, we investigated baseline prostate specific antigen (PSA) levels in first-time screened men, across a 25-year period. In total, 72,654 men, aged 50-79, underwent first-time PSA screening in Gunma prefecture between 1992 and 2016. Changes in the distribution of PSA levels were investigated, including the percentage of men with a PSA above cut-off values and linear regression analyses comparing log 10 PSA with age. The 'ultimate incidence' of PC and clinically significant PC (CSPC) were estimated using the PC risk calculator. Changes in the age-standardized incidence rate (AIR) during this period were analyzed. The calculated coefficients of linear regression for age versus log 10 PSA fluctuated during the 25-year period, but no trend was observed. In addition, the percentage of men with a PSA above cut-off values varied in each 5-year period, with no specific trend. The 'risk calculator (RC)-based AIR' of PC and CSPC were stable between 1992 and 2016. Therefore, the baseline risk for developing PC has remained unchanged in the past 25 years, in Japan. The drastic increase in the incidence of PC, beginning around 2000, may be primarily due to increased PSA screening in the country. © 2018 UICC.
Measuring and modeling the lifetime of nitrous oxide including its variability
NASA Astrophysics Data System (ADS)
Prather, Michael J.; Hsu, Juno; DeLuca, Nicole M.; Jackman, Charles H.; Oman, Luke D.; Douglass, Anne R.; Fleming, Eric L.; Strahan, Susan E.; Steenrod, Stephen D.; Søvde, O. Amund; Isaksen, Ivar S. A.; Froidevaux, Lucien; Funke, Bernd
2015-06-01
The lifetime of nitrous oxide, the third-most-important human-emitted greenhouse gas, is based to date primarily on model studies or scaling to other gases. This work calculates a semiempirical lifetime based on Microwave Limb Sounder satellite measurements of stratospheric profiles of nitrous oxide, ozone, and temperature; laboratory cross-section data for ozone and molecular oxygen plus kinetics for O(1D); the observed solar spectrum; and a simple radiative transfer model. The result is 116 ± 9 years. The observed monthly-to-biennial variations in lifetime and tropical abundance are well matched by four independent chemistry-transport models driven by reanalysis meteorological fields for the period of observation (2005-2010), but all these models overestimate the lifetime due to lower abundances in the critical loss region near 32 km in the tropics. These models plus a chemistry-climate model agree on the nitrous oxide feedback factor on its own lifetime of 0.94 ± 0.01, giving N2O perturbations an effective residence time of 109 years. Combining this new empirical lifetime with model estimates of residence time and preindustrial lifetime (123 years) adjusts our best estimates of the human-natural balance of emissions today and improves the accuracy of projected nitrous oxide increases over this century.
Measuring and modeling the lifetime of nitrous oxide including its variability
Prather, Michael J.; Hsu, Juno; DeLuca, Nicole M.; ...
2015-05-14
The lifetime of nitrous oxide, the third-most-important human-emitted greenhouse gas, is based to date primarily on model studies or scaling to other gases. This work calculates a semiempirical lifetime based on Microwave Limb Sounder satellite measurements of stratospheric profiles of nitrous oxide, ozone, and temperature; laboratory cross-section data for ozone and molecular oxygen plus kinetics for O( 1D); the observed solar spectrum; and a simple radiative transfer model. The result is 116 ± 9 years. The observed monthly-to-biennial variations in lifetime and tropical abundance are well matched by four independent chemistry-transport models driven by reanalysis meteorological fields for the periodmore » of observation (2005–2010), but all these models overestimate the lifetime due to lower abundances in the critical loss region near 32 km in the tropics. These models plus a chemistry-climate model agree on the nitrous oxide feedback factor on its own lifetime of 0.94 ± 0.01, giving N 2O perturbations an effective residence time of 109 years. Combining this new empirical lifetime with model estimates of residence time and preindustrial lifetime (123 years) adjusts our best estimates of the human-natural balance of emissions today and improves the accuracy of projected nitrous oxide increases over this century.« less
Breastfeeding and Mental and Motor Development at 5 ½ Years
Clark, Katy M.; Castillo, Marcela; Calatroni, Agustin; Walter, Tomas; Cayazzo, Marisol; Pino, Paulina; Lozoff, Betsy
2006-01-01
Objective Breastfeeding is associated with better child development outcomes, but uncertainty remains primarily due to the close relationship between breastfeeding and socioeconomic status. This study assesses the issue in a low socioeconomic status sample where breastfeeding was close to universal. Methods 784 Chilean children were followed longitudinally from infancy. All but 4 were initially breastfed, 40% nursed beyond 12 months, and infant growth was normal. Child development was assessed at 5 ½ years by a cognitive, language, and motor test battery. The duration of breastfeeding as the sole milk source was analyzed as a continuous variable, adjusting for a comprehensive set of background factors. Results The relationship between breastfeeding and most 5 ½ -year developmental outcomes was non-linear, with poorer outcome for periods of breastfeeding as the sole milk source for < 2 months or > 8 months – statistically significant for language, motor, and one comprehensive cognitive test, with a suggestive trend for IQ. Conclusions The observed non-linear relationships showed that breastfeeding as the sole milk source for < 2 months or > 8 months, compared to 2–8 months, was associated with poorer development in this sample. The latter finding requires replication in other samples where long breastfeeding is common and socioeconomic status is relatively homogeneous. PMID:16530141
Productivity patterns in the equatorial Pacific over the last 30,000 years
NASA Astrophysics Data System (ADS)
Costa, Kassandra M.; Jacobel, Allison W.; McManus, Jerry F.; Anderson, Robert F.; Winckler, Gisela; Thiagarajan, Nivedita
2017-05-01
The equatorial Pacific traverses a number of productivity regimes, from the highly productive coastal upwelling along Peru to the near gyre-like productivity lows along the international dateline, making it an ideal target for investigating how biogeochemical systems respond to changing oceanographic conditions over time. However, conflicting reconstructions of productivity during periods of rapid climate change, like the last deglaciation, render the spatiotemporal response of equatorial Pacific productivity ambiguous. In this study, surface productivity since the last glacial period (30,000 years ago) is reconstructed from seven cores near the Line Islands, central equatorial Pacific, and integrated with productivity records from across the equatorial Pacific. Three coherent deglacial patterns in productivity are identified: (1) a monotonic glacial-Holocene increase in productivity, primarily along the Equator, associated with increasing nutrient concentrations over time; (2) a deglacial peak in productivity 15,000 years ago due to transient entrainment of nutrient rich southern-sourced deep waters; and (3) possible precessional cycles in productivity in the eastern equatorial Pacific that may be related to Intertropical Convergence Zone migration and potential interactions with El Niño-Southern Oscillation dynamics. These findings suggest that productivity was generally lower during the glacial period, a trend observed zonally across the equatorial Pacific, while deglacial peaks in productivity may be prominent only in the east.
[Prescription drug abuse in elderly psychiatric patients].
Wetterling, Tilman; Schneider, Barbara
2012-08-01
Due to demographic changes there will be a fraction of elderly patients with substance use disorders. However, only a few data have been published about elderly abusers of prescription drugs. Since substance abuse is frequently comorbid with psychiatric disorders, treatment in a psychiatric hospital is often needed. In this explorative study elderly people with prescription drug abuse who required psychiatric inpatient treatment should be characterized. This study was part of the gerontopsychiatry study Berlin (Gepsy-B), an investigation of the data of all older inpatients (≥ 65 years) admitted to a psychiatric hospital within a period of 3 years. Among 1266 documented admissions in 110 cases (8.7 %) (mean age: 75.7 ± 7.1 years) prescription drug abuse, mostly of benzodiazepines was diagnosed. Females showed benzodiazepine abuse more often than males. In only a small proportion of the cases the reason for admission was withdrawal of prescribed drugs. 85.5 % suffered from psychiatric comorbidity, mostly depression. As risk factors for abuse depressive symptoms (OR: 3.32) as well as concurrent nicotine (OR: 2.69) or alcohol abuse (OR: 2.14) were calculated. Psychiatric inpatient treatment was primarily not necessary because of prescription drug abuse but because of other psychopathological symptoms. © Georg Thieme Verlag KG Stuttgart · New York.
Eco-exergy and emergy based self-organization of three forest plantations in lower subtropical China
Lu, Hongfang; Fu, Fangyan; Li, Hao; Campbell, Daniel E.; Ren, Hai
2015-01-01
The bio-thermodynamic structures of a mixed native species plantation, a conifer plantation and an Acacia mangium plantation in Southern China were quantified over a period of 15 years based on eco-exergy methods. The efficiencies of structural development and maintenance were quantified through an integrated application of eco-exergy and emergy methods. The results showed that the storage of eco-exergy increased over 3 times in all three plantations, as predicted by the maximum eco-exergy principle. This trend was primarily seen due to the accumulation of biomass, instead of an increase in the specific eco-exergy (eco-exergy per unit biomass), although species richness did increase. The eco-exergy to emergy and eco-exergy to empower ratios of the three plantations generally increased during the study period, but the rate of increase slowed down after 20 years. The dominant trees are the largest contributors to the eco-exergy stored in the plantations, and thus, the introduction of suitable indigenous tree species should be considered after the existing trees pass through their period of most rapid growth or around 20 years after planting. The combined application of C-values and suggested weighting factors in the eco-exergy calculation can imply opposite results, but may also supply useful information for forest management. PMID:26486821
Growing Physics and Astronomy at James Madison University
NASA Astrophysics Data System (ADS)
Whisnant, C. Steven
2010-02-01
James Madison University is a public, primarily undergraduate institution with a student enrollment of over 18,000. We have a 10.8% minority population and a 60:40 female/male ratio. Drawing 29% of its students from other states, JMU serves a diverse student body. Since the mid '90's, the Department of Physics and Astronomy has grown to 110 majors. There are 15 tenured/tenure-track and 6 non-tenure-track full-time faculty in the department. Graduation rates have grown from five or fewer/year to typically 15-20/year. Eleven faculty are currently engaged in externally funded research with undergraduates. In the 2007-2008 academic year, 45 students were engaged in research. We produced a total of 89 publications and presentations that included 27 students as authors or co-authors. The growth of our department over the last decade is due to a variety of reforms. Foremost among the changes under the control of the department are the initiation of our multi-track BS and BA degree programs and a renewed focus on undergraduate research. These and other significant factors contributing to our success such as student recruiting, outreach, teaching and research integration/balance, promotion of a department culture, visibility on-and off-campus, and university support will be discussed. )
Kornilova, Marina S; Batluk, Julia V; Yorick, Roman V; Baughman, Andrew L; Hillis, Susan D; Vitek, Charles R
2017-03-01
A 2006 survey of street youth at pre-mapped street youth locations in St. Petersburg, Russia, found extremely high HIV seroprevalence (37.4%) among 313 street youth aged 15-19 years of age, strongly associated with injection drug use, which was reported by 50.6% of participants. In response, multi-sectoral social support and prevention measures were instituted. In 2012, we conducted a follow-up survey of 15- to 19-year-old street youth using the same study procedures as in 2006. Of 311 participants, 45 (14.5%) reported injection drug use; 31 participants (10.0%, 95% confidence interval, 6.0%-16.2%) were HIV-seropositive . Predictors independently associated with HIV seropositivity included injection drug use (adjusted prevalence ratio 53.1) and transactional sex (adjusted prevalence ratio 1.3). None of the 178 participants aged 15-17 years were HIV-positive. Thirty of 31 (96.8%) HIV-seropositive individuals reported injection drug use. Street youth in St Petersburg had a 73% decrease in HIV seroprevalence from 2006 to 2012, primarily due to decreased initiation of injection drug use. This marked reduction in the HIV epidemic among street youth occurred after implementation of extensive support programs and socio-economic improvements.
ERIC Educational Resources Information Center
Coffin, Caroline; O'Halloran, Kieran A.
2009-01-01
Just over 10 years ago, "Educational Review" published an article "Reconceiving argument" by Richard Andrews. In the article, Andrews traced some of the changes in the conception of argument that had taken place within educational contexts (primarily within the UK) over the previous few years. An important aim of the authors'…
Software Deficiency Issues Confronting the Utilization of ’Non-von Neumann’ Architectures
1989-01-01
upon work done by Charles Babbage nearly 100 years before. Hence, the " Babbage " machine that was designed in the 1820’s and 1830’s is generally...functionality. For example, consider the world’s first computer designer, Charles Babbage , who primarily designed in the 1820’s what is considered to be the...primarily considered as direct descendants of ideas that were devised in the 1930’s, these ideas were basically rediscoveries of what Charles Babbage
Proteomic analyses of host and pathogen responses during bovine mastitis.
Boehmer, Jamie L
2011-12-01
The pursuit of biomarkers for use as clinical screening tools, measures for early detection, disease monitoring, and as a means for assessing therapeutic responses has steadily evolved in human and veterinary medicine over the past two decades. Concurrently, advances in mass spectrometry have markedly expanded proteomic capabilities for biomarker discovery. While initial mass spectrometric biomarker discovery endeavors focused primarily on the detection of modulated proteins in human tissues and fluids, recent efforts have shifted to include proteomic analyses of biological samples from food animal species. Mastitis continues to garner attention in veterinary research due mainly to affiliated financial losses and food safety concerns over antimicrobial use, but also because there are only a limited number of efficacious mastitis treatment options. Accordingly, comparative proteomic analyses of bovine milk have emerged in recent years. Efforts to prevent agricultural-related food-borne illness have likewise fueled an interest in the proteomic evaluation of several prominent strains of bacteria, including common mastitis pathogens. The interest in establishing biomarkers of the host and pathogen responses during bovine mastitis stems largely from the need to better characterize mechanisms of the disease, to identify reliable biomarkers for use as measures of early detection and drug efficacy, and to uncover potentially novel targets for the development of alternative therapeutics. The following review focuses primarily on comparative proteomic analyses conducted on healthy versus mastitic bovine milk. However, a comparison of the host defense proteome of human and bovine milk and the proteomic analysis of common veterinary pathogens are likewise introduced.
Abookire, Alisa A.; Norcross, Brenda L.
1998-01-01
Three transects in Kachemak Bay, Alaska, were sampled in September 1994, May and August 1995, and February, May, and August 1996. Juvenile flathead sole, Hippoglossoides elassodon, and rock sole, Pleuronectes bilineatus, were the most abundant flatfishes, comprising 65-85% of all fiatfishes captured at any period. Collections of fish and sediments were made at regular depth contour intervals of l0 m. Habitat distribution was described by depth at 10 m increments and sediment percent weights of gravel, sand, and mud. Year-round habitat of flathead sole age-0 was primarily from 40 to 60 m, and age-1 habitat was primarily from 40 to 80 m. Summer habitat of rock sole age-0 and -1 was from 10 to 30 m, and in winter they moved offshore to depths of up to 150 m. Both age classes of flathead sole were most abundant on mixed mud sediments, while age-1 were also in high abundance on muddy sand sediments. Rock sole age-0 and -1 were most abundant on sand, though age-1 were also found on a variety of sediments both finer and coarser grained than sand. Flathead sole and rock sole had distinctive depth and sediment habitats. When habitat overlap occurred between the species, it was most often due to rock sole moving offshore in the winter. Abundances were not significantly different among seasons for age-1 flatfishes.
Lefcheck, Jonathan S; Wilcox, David J; Murphy, Rebecca R; Marion, Scott R; Orth, Robert J
2017-09-01
Interactions among global change stressors and their effects at large scales are often proposed, but seldom evaluated. This situation is primarily due to lack of comprehensive, sufficiently long-term, and spatially extensive datasets. Seagrasses, which provide nursery habitat, improve water quality, and constitute a globally important carbon sink, are among the most vulnerable habitats on the planet. Here, we unite 31 years of high-resolution aerial monitoring and water quality data to elucidate the patterns and drivers of eelgrass (Zostera marina) abundance in Chesapeake Bay, USA, one of the largest and most valuable estuaries in the world, with an unparalleled history of regulatory efforts. We show that eelgrass area has declined 29% in total since 1991, with wide-ranging and severe ecological and economic consequences. We go on to identify an interaction between decreasing water clarity and warming temperatures as the primary drivers of this trend. Declining clarity has gradually reduced eelgrass cover the past two decades, primarily in deeper beds where light is already limiting. In shallow beds, however, reduced visibility exacerbates the physiological stress of acute warming, leading to recent instances of decline approaching 80%. While degraded water quality has long been known to influence underwater grasses worldwide, we demonstrate a clear and rapidly emerging interaction with climate change. We highlight the urgent need to integrate a broader perspective into local water quality management, in the Chesapeake Bay and in the many other coastal systems facing similar stressors. © 2017 John Wiley & Sons Ltd.
History of nutrient inputs to the northeastern United States, 1930-2000
NASA Astrophysics Data System (ADS)
Hale, Rebecca L.; Hoover, Joseph H.; Wollheim, Wilfred M.; Vörösmarty, Charles J.
2013-04-01
Humans have dramatically altered nutrient cycles at local to global scales. We examined changes in anthropogenic nutrient inputs to the northeastern United States (NE) from 1930 to 2000. We created a comprehensive time series of anthropogenic N and P inputs to 437 counties in the NE at 5 year intervals. Inputs included atmospheric N deposition, biological N2 fixation, fertilizer, detergent P, livestock feed, and human food. Exports included exports of feed and food and volatilization of ammonia. N inputs to the NE increased throughout the study period, primarily due to increases in atmospheric deposition and fertilizer. P inputs increased until 1970 and then declined due to decreased fertilizer and detergent inputs. Livestock consistently consumed the majority of nutrient inputs over time and space. The area of crop agriculture declined during the study period but consumed more nutrients as fertilizer. We found that stoichiometry (N:P) of inputs and absolute amounts of N matched nutritional needs (livestock, humans, crops) when atmospheric components (N deposition, N2 fixation) were not included. Differences between N and P led to major changes in N:P stoichiometry over time, consistent with global trends. N:P decreased from 1930 to 1970 due to increased inputs of P, and increased from 1970 to 2000 due to increased N deposition and fertilizer and decreases in P fertilizer and detergent use. We found that nutrient use is a dynamic product of social, economic, political, and environmental interactions. Therefore, future nutrient management must take into account these factors to design successful and effective nutrient reduction measures.
ERIC Educational Resources Information Center
Perez-Felkner, Lara; Thomas, Kirby; Hopkins, Jordan; Nix, Samantha
2015-01-01
Given the explosion of theoretical and empirical interest in the STEM gender gap in recent years, almost exclusively focused on four-year colleges, this paper primarily investigates the following question: How does the nature of the gender gap differ among two- and four-year college students, if at all? This study seeks to answer the following…
Forage response to nitrogen and phosphorus fertilization in a 25-year-old plantation of slash pine
Ralph H. Hughes; George W. Bengston; Thaddeus a. Harrington
1971-01-01
In a 25-year-old plantation of slash pine near Olustee, Florida, a single application of 200 lb. of nitrogen and 44 lb. of phosphorus per acre increased production of herbaccous understory (primarily native bluestem grasses) to more than a ton per acre the first year, a fifefold increase. Production declined sharply the second year, and the response disappeared in the...
ERIC Educational Resources Information Center
Hsueh, JoAnn; Lowenstein, Amy E.; Morris, Pamela; Mattera, Shira K.; Bangser, Michael
2014-01-01
This report presents exploratory impact findings for 3-year-olds from the Head Start CARES demonstration, a large-scale randomized controlled trial implemented in Head Start centers for one academic year across the country. The study was designed primarily to test the effects of the enhancements on 4-year-olds, but it also provides an opportunity…
ERIC Educational Resources Information Center
Inside English, 1976
1976-01-01
Designed primarily for English faculty at two-year colleges in California, "Inside English" includes articles on major instructional, curricular, administrative, and employment issues of concern to teachers in the field as well as information on the activities of the English Council of the California Two-Year Colleges (ECCTYC). The December 1975…
ERIC Educational Resources Information Center
Booth, Richard E., Ed.
1978-01-01
Designed primarily for English faculty at two-year colleges in California, "Inside English" includes articles on major instructional, curricular, administrative, and employment issues of concern to teachers in the field as well as information on the activities of the English Council of the California Two-Year Colleges (ECCTYC). The Fall 1977, and…
ERIC Educational Resources Information Center
Southard, Jonathan N.
2014-01-01
Instrumentation for real-time PCR is used primarily for amplification and quantitation of nucleic acids. The capability to measure fluorescence while controlling temperature in multiple samples can also be applied to the analysis of proteins. Conformational stability and changes in stability due to ligand binding are easily assessed. Protein…
USDA-ARS?s Scientific Manuscript database
Human illness due to the foodborne bacterial pathogen Listeria monocytogenes frequently involves certain widely disseminated clonal complexes (CCs), primarily of serotype 4b. CC1, CC2 and CC6, previously also designated epidemic clone (EC) I, Ia and II, respectively, have been frequently implicate...
Submicron Surface-Patterned Fibers and Textiles
2016-11-04
These authors contributed equally Keywords: grating, fiber, polymer , patterning, textile Distribution A: approved for public release...requirements. Second, textile materials are primarily polymer -based, while most surface-patterning techniques have been developed for silicon...Alternative substrates, especially flexible polymers , remain challenging to pattern [25,26] due to the highly specific surface chemistry of different
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-07
... public forum and to submit written comments. Southeastern will evaluate all comments received in this... due primarily to revenue from stream-flow energy that has been less than previously estimated as a..., Incorporated. The customer is responsible for providing a scheduling arrangement with the Government. Rate...
EFFECTS OF HABITAT DEGRADATION ON BIOLOGICAL ENDPOINTS IN THE SOUTH FORK BROAD RIVER BASIN, GEORGIA
Many of the streams of the lower Piedmont ecoregion in Georgia have been negatively impacted to some degree by habitat degradation due primarily to sedimentation. The South Fork of the Broad River watershed has been designated as sediment impacted under Section 303(d) of the Clea...
Properties, flowback, and wellbore displacement
DOE Office of Scientific and Technical Information (OSTI.GOV)
Poulson, D.K.
1981-10-19
Carbon dioxide was introduced as an additive to acid and fracture jobs in 1962. Since then, its use as a well-servicing medium has grown rapidly. This has been due primarily to its excellent flowback properties, although it also offers other advantages. These advantages are described along with methods for making calculations with CO/sub 2/. 7 refs.
Altered States of Consciousness and Alcohol.
ERIC Educational Resources Information Center
Jones, Ben Morgan; And Others
This document contains the reports of research at a symposium on "Altered States of Consciousness and Alcohol." The participants primarily agreed that alcohol induces an altered state of consciousness similar to other drugs, but that this phenomenon has not been explicitly stated due to the current interest in newer and more novel drugs. The…
Aerobic Exercise and Other Healthy Lifestyle Factors That Influence Vascular Aging
ERIC Educational Resources Information Center
Santos-Parker, Jessica R.; LaRocca, Thomas J.; Seals, Douglas R
2014-01-01
Cardiovascular diseases (CVDs) remain the leading cause of death in the United States and other modern societies. Advancing age is the major risk factor for CVD, primarily due to stiffening of the large elastic arteries and the development of vascular endothelial dysfunction. In contrast, regular aerobic exercise protects against the development…
USDA-ARS?s Scientific Manuscript database
Tuberculosis (TB) in elephants is a re-emerging zoonotic disease caused primarily by Mycobacterium tuberculosis. Current methods for screening and diagnosis rely on trunk wash culture, which has serious limitations due to low test sensitivity, slow turn-around time, and variable sample quality. Inn...
The Salivary Anti-A and Anti-B Isoantibody System in Group O Males.
agglutinins increased significantly in two individuals and anti-B in four, and parotid saliva anti-A agglutinins in one and anti-B in three. Both whole...and parotid saliva agglutinating activity were demonstrated to be primarily due to secretory IgA, both pre- and postimmunization. IgG coating activity
ERIC Educational Resources Information Center
Barriga, Alvaro Q.; Doran, Jeffrey W.; Newell, Stephanie B.; Morrison, Elizabeth M.; Barbetti, Victor; Robbins, Brent Dean
2002-01-01
This study examined relationships among eight teacher-reported problem behavior syndromes and standardized measures of academic achievement among 58 adolescents in an alternative school. Analysis suggested association between attention problems and academic achievement was primarily due to inattention component of the syndrome rather than the…
Development of soybean with novel sources of resistance to Phomopsis seed decay
USDA-ARS?s Scientific Manuscript database
Phomopsis seed decay (PSD) is an important soybean disease that results in poor seed quality in most soybean production areas of the United States. PSD is caused primarily by the fungal pathogen Phomopsis longicolla. In 2009, due to the prevalence of hot and humid environments from pod fill to harve...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-14
... species' use of live pines may have evolved in response to living in a fire-maintained ecosystem where... declined primarily due to conversion of mature pine forests to young pine plantations, agricultural fields... wetlands, pine flatwoods, and agricultural fields, which are currently the only remaining foraging habitat...
FT–Raman investigation of bleaching of spruce thermomechanical pulp
U.P. Agarwal; L.L. Landucci
2004-01-01
Spruce thermomechanical pulp was bleached initially by alkaline hydrogen peroxide and then by sodium dithionite and sodium borohydride. Near-infrared Fourier-transformâRaman spectroscopy revealed that spectral differences were due primarily to coniferaldehyde and p-quinone structures in lignin, new direct evidence that bleaching removes p-quinone structures. In...
Towards a Theory of Psychosocial Development and Fertility Control.
ERIC Educational Resources Information Center
Cvetkovich, George
It is popularly held that the low rate of birth control use among sexually-active American teenagers is primarily due to their immaturity. Many teenagers are commencing their sexual careers prior to acquisition of the social and cognitive abilities demanded by responsible contraceptive use. A general decision-making framework can be used to create…
USDA-ARS?s Scientific Manuscript database
For many sugarcane producers in Louisiana the only fertilizer that is routinely applied to their crop is nitrogen that is side-dressed in the spring. This is due, primarily to the high cost of potassium and phosphorus fertilizers. Recent cooperative research conducted between the USDA/ARS Sugarcane ...
ERIC Educational Resources Information Center
Giallourakis, Michael C.; Lorenz, Margaret A.
One factor identified as vital to managerial success is that of being a part of a mentor relationship. That this is primarily a male relationship is due to subtle communication patterns within organizations that have grown out of male experiences with team sports and therefore exclude women. Among the various barriers women in organizations must…
ERIC Educational Resources Information Center
Thomson, Margareta Maria; Kaufmann, Elisha
2013-01-01
This study explored primarily the elementary teachers' motivations and expectations for engagement in a science professional development. Participants (N=20) were elementary teachers in two public schools from the United States and were enrolled in a yearlong science professional development; however, due to various factors teachers did not…
Pre-Teens' Informal Learning with ICT and Web 2.0
ERIC Educational Resources Information Center
Ferguson, Rebecca; Faulkner, Dorothy; Whitelock, Denise; Sheehy, Kieron
2015-01-01
Information and communication technology (ICT) and Web 2.0 have the potential to impact on learning by supporting inquiry, literacies, collaboration and publication. Restrictions on the use of these tools within schools, primarily due to concerns about discipline and child safety, make it difficult to make full use of this potential in formal…
Model Minority, Self-Perception and Schooling: Multiple Voices of Korean Students in China
ERIC Educational Resources Information Center
Gao, Fang
2009-01-01
Koreans have been successful in nesting their educational achievement in places like China, where they have earned the title of the "model minority", due primarily to their educational success. Drawing on data from ethnographic research on fourth-grade Korean students in a bilingual Korean school, this article examines the relationship…
Manpower Requirements Report FY 1994
1993-06-01
decrease in FY 1993 is primarily due to reductions in advanced weapons (-144), aerospace avionics (-48), materials (-37), and test and evaluation support...sub- sistence, medical goods, industrial and construction material , general and electronic supplies, and petroleum products. Logistic services include...efficiencies resulting from streamlining depots, modernizing/automating materials handling, and a projected decline in contract administration and
USDA-ARS?s Scientific Manuscript database
Tuberculosis (TB), primarily due to Mycobacterium tuberculosis in humans and Mycobacterium bovis in cattle, is an exemplary model of the One Health Concept. The human TB vaccine, M. bovis bacille Calmette-Guerin (BCG), was first proven effective in cattle prior to use in humans. Recent experimental ...
Synthesis of metal nanoparticles (NPs) has been the topic of intense research during the last decade. This is primarily due to their unique properties and potential applications from the technological point of view. The optical,[1] electronic,[2] magnetic,[3] and catalytic [4] pr...
Experiences of LGBTQ Students at a Primarily White Institution in the South
ERIC Educational Resources Information Center
Cain, Leia Kristin
2015-01-01
In the United States, often Lesbian, Gay, Bisexual, Transgender, Queer, and/or Questioning (LGBTQ) students are targets of verbal harassment and violence due to their sexual orientation or gender identity and gender expression. Further, 31 states do not offer protection against sexuality- or gender identity-based discrimination (ACLU, 2015).…
T.J. Antrobus; M.P. Guilfoyle; W.C. Barrow; Paul B. Hamel; J.S. Wakeley
2000-01-01
Neotropical migrants are birds that breed in North America and winter primarily in Central and South America. Longterm population studies of birds in the Eastern United States indicated declines of some forest-dwelling birds, many of which winter in the Neotropics (Peterjohn and others 1995). These declines were attributed to loss of wintering and breeding habitat due...
Using Forest Health Monitoring to assess aspen forest cover change in the southern Rockies ecoregion
Paul Rogers
2002-01-01
Long-term qualitative observations suggest a marked decline in quaking aspen (Populus tremuloides Michx.) primarily due to advancing succession and fire suppression. This study presents an ecoregional coarse-grid analysis of the current aspen situation using Forest Health Monitoring (FHM) data from Idaho, Wyoming, and Colorado. A...
USDA-ARS?s Scientific Manuscript database
Tuberculosis (TB), primarily due to Mycobacterium tuberculosis in humans and Mycobacterium bovis in cattle, is a classic model of the One Health Concept. M. bovis Bacillus Calmette Guerin (BCG) was first proven effective in cattle prior to use in humans. Recent experimental trials with cattle have d...
USDA-ARS?s Scientific Manuscript database
Tuberculosis (TB), primarily due to Mycobacterium tuberculosis in humans and Mycobacterium bovis in cattle, is a classic model for demonstration of the One Health Concept. Early studies with cattle were instrumental in the development of the use of Koch’s tuberculin as an in vivo measure of cell-med...
Whitebark and limber pine restoration and monitoring in Glacier National Park
Jennifer M. Asebrook; Joyce Lapp; Tara. Carolin
2011-01-01
Whitebark pine (Pinus albicaulis) and limber pine (Pinus flexilis) are keystone species important to watersheds, grizzly and black bears, squirrels, birds, and other wildlife. Both high elevation five-needled pines have dramatically declined in Glacier National Park primarily due to white pine blister rust (Cronartium ribicola) and fire exclusion, with mountain pine...
The health effects of long-term exposure to volatile organic compounds (VOCs) are poorly understood, due primarily to insufficient human exposure data and inconsistent animal models. To develop a rodent model of long-term exposure to VOCs, a sub-chronic inhalation study with mult...
USDA-ARS?s Scientific Manuscript database
Higher concentrations of anthocyanins in vegetables are important for attractive appearance and may offer health benefits for consumers. The red color of onion bulbs is due primarily to the accumulation of anthocyanins. The goals of this study were to identify chromosome regions that condition yello...
The Program of Special Directed Studies: A Five Year Summary.
ERIC Educational Resources Information Center
Mornell, Eugene S.
The report described one relatively small but extensively researched special admission and compensatory education program at The Claremont Colleges, California. The Program of Special Directed Studies for Transition to College (PSDS) was administered by the Claremont University Center. PSDS was a 5-year experimental project primarily funded by the…
Evaluation of Innovative Schools: OCDQ Results for Fifth-Year Teachers, 1970-1971.
ERIC Educational Resources Information Center
Broward County School Board, Fort Lauderdale, FL.
A random sample is reported of fifth-year teachers from conventional schools and from open or innovative schools who completed the Organizational Climate Descriptions Questionnaire (OCDQ), administered anonymously, which measured subjective rather than objective dimensions. The instrument is interpreted as being primarily a measure of teacher…
Change in Teachers' Knowledge of Subject Matter: A 17-Year Longitudinal Study
ERIC Educational Resources Information Center
Arzi, Hanna J.; White, Richard T.
2008-01-01
This longitudinal study explored change in teachers' knowledge of subjects they teach from preservice training through 17 years of professional experience. It followed secondary school science teachers in Australia, through sequences of individual interviews in which change in content knowledge (mainly energy-related) was probed primarily via…
Emerging Understanding of Patterning in 4-Year-Olds
ERIC Educational Resources Information Center
Rittle-Johnson, Bethany; Fyfe, Emily R.; McLean, Laura E.; McEldoon, Katherine L.
2013-01-01
Young children have an impressive amount of mathematics knowledge, but past psychological research has focused primarily on their number knowledge. Preschoolers also spontaneously engage in a form of early algebraic thinking-patterning. In the current study, we assessed 4-year-old children's knowledge of repeating patterns on two occasions…
Masting characteristics of white oak: implications for management
Marcus A. Lashley; John M. McCord; Cathryn H. Greenberg; Craig A. Harper
2009-01-01
Acorn production is variable from year to year and among species. Weather, insect damage, and genetics are primary causes for variation. Silvicultural techniques have been recommended to improve acorn production; however, those recommendations primarily address variation among red oaks (Quercus rubra). Variability among individual white oaks (Quercus alba) has not been...
Anatomy of a bottleneck: diagnosing factors limiting population growth in the Puerto Rican parrot
Beissenger, S.R.; Wunderle, J.M.; Meyers, J.M.; Saether, B.-E.; Engen, S.
2008-01-01
The relative importance of genetic, demographic, environmental, and catastrophic processes that maintain population bottlenecks has received little consideration. We evaluate the role of these factors in maintaining the Puerto Rican Parrot (Amazona vittata) in a prolonged bottleneck from 1973 through 2000 despite intensive conservation efforts. We first conduct a risk analysis, then examine evidence for the importance of specific processes maintaining the bottleneck using the multiple competing hypotheses approach, and finally integrate these results through a sensitivity analysis of a demographic model using life-stage simulation analysis (LSA) to determine the relative importance of genetic, demographic, environmental, and catastrophic processes on population growth. Annual population growth has been slow and variable (1.0 6 5.2 parrots per year, or an average k?1.05 6 0.19) from 16 parrots (1973) to a high of 40-42 birds (1997-1998). A risk analysis based on population prediction intervals (PPI) indicates great risk and large uncertainty, with a range of 22?83 birds in the 90% PPI only five years into the future. Four primary factors (reduced hatching success due to inbreeding, failure of adults to nest, nest failure due to nongenetic causes, and reduced survival of adults and juveniles) were responsible for maintaining the bottleneck. Egghatchability rates were low (70.6% per egg and 76.8% per pair), and hatchability increased after mate changes, suggesting inbreeding effects. Only an average of 34% of the population nested annually, which was well below the percentage of adults that should have reached an age of first breeding (41-56%). This chronic failure to nest appears to have been caused primarily by environmental and/or behavioral factors, and not by nest-site scarcity or a skewed sex ratio. Nest failure rates from nongenetic causes (i.e., predation, parasitism, and wet cavities) were low (29%) due to active management (protecting nests and fostering captive young into wild nests), diminishing the importance of nest failure as a limiting factor. Annual survival has been periodically reduced by catastrophes (hurricanes), which have greatly constrained population growth, but survival rates were high under non-catastrophic conditions. Although the importance of factors maintaining the Puerto Rican Parrot bottleneck varied throughout the 30-year period of study, we determined their long-term influence using LSA simulations to correlate variation in demographic rates with variation in population growth (k). The bottleneck appears to have been maintained primarily by periodic catastrophes (hurricanes) that reduced adult survival, and secondarily by environmental and/or behavioral factors that resulted in a failure of many adults to nest. The influence of inbreeding through reduced hatching success played a much less significant role, even when additional effects of inbreeding on the production and mortality of young were incorporated into the LSA. Management actions needed to speed recovery include (1) continued nest guarding to minimize the effects of nest failure due to nongenetic causes; (2) creating a second population at another location on the island --a process that was recently initiated--to reduce the chance that hurricane strikes will cause extinction; and (3) determining the causes of the low percentage of breeders in the population and ameliorating them, which would have a large impact on population growth.
Indonesia Country Analysis Brief
2015-01-01
Indonesia is reorienting energy production from serving primarily export markets to meeting its growing domestic consumption. Indonesia's energy industry has faced challenges in recent years from regulatory uncertainty and inadequate investment.
Butler, C; Watson-Wright, W M; Wilkinson, M; Johnstone, D E; Armour, J A
1988-03-01
Electrical stimulation of an acutely decentralized stellate or middle cervical ganglion or cardiopulmonary nerve augments cardiac chronotropism or inotropism; as the stimulation continues there is a gradual reduction of this augmentation following the peak response, i.e., an inhibition of augmentation. The amount of this inhibition was found to be dependent upon the region of the heart investigated and the neural structure stimulated. The cardiac parameters which were augmented the most displayed the greatest inhibition. Maximum augmentation or inhibition occurred, in most instances, when 5-20 Hz stimuli were used. Inhibition of augmentation was overcome when the stimulation frequency was subsequently increased or following the administration of nicotine or tyramine, indicating that the inhibition was not primarily due to the lack of availability of noradrenaline in the nerve terminals of the efferent postganglionic sympathetic neurons. Furthermore, as infusions of isoproterenol or noradrenaline during the period of inhibition could still augment cardiac responses, whereas during the early peak responses they did not, the inhibition of augmentation does not appear to be due primarily to down regulation of cardiac myocyte beta-adrenergic receptors. The inhibition was modified by hexamethonium but not by phentolamine or atropine. Inhibition occurred when all ipsilateral cardiopulmonary nerves connected with acutely decentralized middle cervical and stellate ganglia were stimulated, whereas significant inhibition did not occur when these nerves were stimulated after they had been disconnected from the ipsilateral decentralized ganglia. Taken together these data indicate that the inhibition of cardiac augmentation which occurs during relatively long-term stimulation of intrathoracic sympathetic neural elements is due in large part to nicotinic cholinergic synaptic mechanisms that lie primarily in the major thoracic autonomic ganglia. They also indicate that long-term stimulation in intrathoracic sympathetic neural elements with frequencies as low as 2 Hz may augment the heart as much as higher stimulation frequencies, depending upon the structure stimulated and the cardiovascular parameter monitored.
Modernization of the migrant women in Dhaka, Bangladesh: analysis of some demographic variables.
Huq-hussain, S
1995-04-01
This study examines demographic factors as signs of change among female rural migrants who settled in the slums of Dhaka, Bangladesh, in 1988. Data are obtained from structured and open-ended interviews among 399 migrant women working in selected clusters of Dhaka in 1988. Short-term migrants lived in Dhaka city for 6 months to 5 years. Long-term migrants lived longer than 5 years in Dhaka city. Findings indicate that 81% of all migrant families were nuclear, 18% were joint, and only 1% were extended. A greater proportion of recent migrants had nuclear families (89%) compared to long-term migrants (78%). 90% of recent migrants and 81% of long-term migrants favored nuclear families. Migrant women indicated that small nuclear families were preferred due to economic hardship and the shortage of housing. Interpersonal quarrels were another reason for their preference for nuclear families. Women who desired joint families found their domestic burdens relieved with more people to share responsibilities. 17% of all migrant households were headed by women (15% among recent migrants and 18% among long-term migrants). Female heads reported that their family structure was due to the death of or divorce from their spouse and the preference of independence from family dependency. 43% of families had 4 members, 36% had 5-7 members, and 21% had over 7 members. 52% of recent migrants and 40% of long-term migrants had small families under 4 members. 39% of long-term migrants and 26% of recent migrants had families with 5-7 members. Recent female migrants were characterized as primarily aged 11-30 years compared to long-term female migrants who were aged mainly under 10 years. A distinctive feature of marriage among migrant women was the larger proportion of women marrying at early ages. 43% were married at ages 11-14 years. 29% of recent migrants and only 11% of long-term migrants supported early age at marriage, but over 50% supported a marriage age of 18-20 years. It is argued that the long-term migrants support for lower fertility and modern values was an adjustment to urban life.
1982-10-01
to dinosaurs , they immediately were faced with - the most fundamental question, "What is a living cell?" One may well say that k the degree of our...primarily a tiny * droplet of water containing proteins and K+ saltskept apart from the body of N 0similar aqueous solution of Na salts by a microscopic...experimental evidence, besides those already mentioned, included the successful demonstration that proteins with its polypeptLde iJl existing in an extended
1981-10-01
documt has bees apoved foz public zeleae and 301 4 C Idixtribution is uaiaIed.83 12 20 1. " Annual Progress Report November 1980 - October 1, 1981...a brief sketch of the historical background. Background Information The most abundant components of the living cells are water, proteins and K7...sites and (b) electrostatic adsorption on fixed anionic sites (primarily 0- and Y-carboxyl groups of cell protein ) favors the smaller hydrated K over Na
Tinea capitis and tinea corporis with a severe inflammatory response due to Trichophyton tonsurans.
Hryncewicz-Gwóźdź, Anita; Beck-Jendroschek, Vera; Brasch, Jochen; Kalinowska, Katarzyna; Jagielski, Tomasz
2011-10-01
Trichophyton tonsurans is an anthropophilic dermatophyte, with a worldwide distribution, although its prevalence varies considerably between different geographical regions. Whereas in North America infections due to this fungus are exceptionally common, on the European continent they appear relatively seldom. Although T. tonsurans is primarily associated with tinea capitis, it can also be the cause of tinea corporis and tinea unguium. The course of infection is usually only mildly symptomatic. We describe here two cases of urease-positive T. tonsurans infections with atypically extensive cutaneous lesions and severe inflammatory responses. .
NASA Astrophysics Data System (ADS)
Schmidt, Cynthia L.
Global forests are experiencing dramatic changes due to changes in climate as well as anthropogenic activities. Increased warming is causing the advancement of some species upslope and northward, while it is also causing widespread mortality due to increased drought conditions. In addition, increasing human population in mountain regions is resulting in elevated risk of human life and property loss due to larger and more severe wildfires. My research focuses on assessing the current vulnerability of forests and their communities in the Sierra Nevada, and how forests are projected to change in the future based on different climate change scenarios. In the first chapter I use Landsat satellite imagery to identify and attribute cause of forest disturbance between 1985 and 2011, primarily focusing on disturbances due to insect, diseases and drought. The change-detection algorithm, Landtrendr, was successfully used to identify forest disturbance, but identifying cause of disturbance was challenging due to the spectral similarities between disturbance types. Landtrendr was most successful in identifying disturbance due to insect, disease and drought in the San Bernardino National Forest, where there is little forest management activity. In the second chapter, I assess whether state or local land use policies in high-fire prone regions exist to reduce the vulnerability of residential developments to wildfire. Three specific land-use tools associated with reducing wildfire vulnerability are identified: (1) buffers around developments; (2) clustered developments; (3) restricting construction on slopes greater than 25%. The study also determines whether demographic and physical characteristics of selected California counties were related to implementing land use policies related to reducing wildfire vulnerability. Results indicate that land use policies related to preventing wildfire-related losses focus on building materials, road access, water availability and vegetation management, not the three identified land-use tools. San Diego County, the county that has experienced the most devastating fires, had the highest percentage of residential developments with both clustering and buffering. The third chapter focuses on future forest conditions. I used a Dynamic Global Vegetation Model (DGVM) to assess future vegetation dynamics and productivity under changing climate and atmospheric CO2 concentrations in the Sierra Nevada. Model results suggest that Temperate Broadleaved Evergreen Plant Functional Types (PFTs) will move upslope and eastward, replacing Temperate Needleleaved PFTs. Boreal Needleleaved Evergreen PFTs, found primarily at higher elevations, will decline dramatically as temperatures continue to increase. Gross Primary Productivity (GPP) will increase as atmospheric CO2 concentration increases, due primarily to the increase in the more productive broadleaved PFTs. Forest ecosystems play an important role in maintaining climate stability at the regional and global scales as a vital carbon sink, so understanding the role of disturbance and climate change will be vital to both scientists and policy makers in the future.
Evidence of global-scale As, Mo, Sb, and Tl atmospheric pollution in the antarctic snow.
Hong, Sungmin; Soyol-Erdene, Tseren-Ochir; Hwang, Hee Jin; Hong, Sang Bum; Hur, Soon Do; Motoyama, Hidaeki
2012-11-06
We report the first comprehensive and reliable time series for As, Mo, Sb, and Tl in the snowpack from Dome Fuji in the central East Antarctic Plateau. Our results show significant enrichment of these elements due to either anthropogenic activities or large volcanic eruptions during the past 50 years. With respect to the values reported from 1960 to 1964, we observed the maximum increases in crustal enrichment factors (EFs) for As (a factor of ~15), Mo (~4), Sb (~4), and Tl (~2) during the period between the 1970s and 1990s, reflecting the global dispersion of anthropogenic pollutants of these elements, even to the most remote areas on Earth. Such enrichments are likely related to emissions of trace elements from nonferrous metal smelting and fossil fuel combustion processes in South America, especially in Chile. A drastic decrease in the As concentration and its EF values was observed after the year 2000 in response to the introduction of environmental regulations in the 1990s to reduce As emissions from the copper industry, primarily in Chile. The observed decrease suggests that governmental regulations for pollution control are effective in reducing air pollution at both the regional and global level.
Cervical artificial disc extrusion after a paragliding accident
Niu, Tianyi; Hoffman, Haydn; Lu, Daniel C.
2017-01-01
Background: Cervical total disc replacement (TDR) is an established alternative to anterior cervical discectomy and fusion (ACDF) with excellent long-term outcomes and low failure rates. Cases of implant failure and migration are scarce and primarily limited to several years postoperatively. The authors report a case of anterior extrusion of a C4-C5 ProDisc-C (DePuy Synthes, West Chester, PA, USA) cervical artificial disc (CAD) 14 months after placement due to minor trauma. Case Description: A 33-year-old female who had undergone C4-C5 CAD implantation presented with neck pain and spasm after experiencing a paragliding accident. A 4 mm anterior protrusion of the CAD was seen on x-ray. She underwent removal of the CAD followed by anterior fusion. Other cases of CAD extrusion in the literature are discussed and the device's durability and testing are considered. Conclusion: Overall, CAD extrusion is a rare event. This case is likely the result of insufficient osseous integration. Patients undergoing cervical TDR should avoid high-risk activities to prevent trauma that could compromise the disc's placement, and future design/research should focus on how to enhance osseous integration at the interface while minimizing excessive heterotopic ossification. PMID:28781915
Cervical artificial disc extrusion after a paragliding accident.
Niu, Tianyi; Hoffman, Haydn; Lu, Daniel C
2017-01-01
Cervical total disc replacement (TDR) is an established alternative to anterior cervical discectomy and fusion (ACDF) with excellent long-term outcomes and low failure rates. Cases of implant failure and migration are scarce and primarily limited to several years postoperatively. The authors report a case of anterior extrusion of a C4-C5 ProDisc-C (DePuy Synthes, West Chester, PA, USA) cervical artificial disc (CAD) 14 months after placement due to minor trauma. A 33-year-old female who had undergone C4-C5 CAD implantation presented with neck pain and spasm after experiencing a paragliding accident. A 4 mm anterior protrusion of the CAD was seen on x-ray. She underwent removal of the CAD followed by anterior fusion. Other cases of CAD extrusion in the literature are discussed and the device's durability and testing are considered. Overall, CAD extrusion is a rare event. This case is likely the result of insufficient osseous integration. Patients undergoing cervical TDR should avoid high-risk activities to prevent trauma that could compromise the disc's placement, and future design/research should focus on how to enhance osseous integration at the interface while minimizing excessive heterotopic ossification.
Advances and Environmental Conditions of Spring Migration Phenology of American White Pelicans
NASA Astrophysics Data System (ADS)
King, D. Tommy; Wang, Guiming; Yang, Zhiqiang; Fischer, Justin W.
2017-01-01
Spring migration phenology of birds has advanced under warming climate. Migration timing of short-distance migrants is believed to be responsive to environmental changes primarily under exogenous control. However, understanding the ecological causes of the advancement in avian spring migration phenology is still a challenge due to the lack of long-term precise location data. We used 11 years of Global Positioning System relocation data to determine four different migration dates of the annual migration cycle of the American white pelican (Pelecanus erythrorhynchos), a short-distance migrant. We also tested the hypothesis that increases in winter temperature and precipitation on the wintering grounds would advance pelican spring migration. Pelican spring departures and arrivals advanced steadily from 2002 to 2011. Spring departure timing exhibited high repeatability at the upper end of migration timing repeatability reported in literature. However, individual spring departure and arrival dates were not related to winter daily temperature, total winter precipitation, and detrended vegetation green-up dates indexed by the normalized difference vegetation index. Despite high repeatability, the observed between-year variation of spring departure dates was still sufficient for the advancement of spring departure timing.
Hernandez-Milian, Almudena; Payeras-Cifre, Antoni
2014-01-01
Listeriosis is a disease caused by Listeria monocytogenes (L. monocytogenes). L. monocytogenes is bacteria that usually infects some determined inhabitants, especially high risk patients such as the elderly, immunosuppressed patients and pregnant women. However, it can also affect people who do not have these risk factors. L. monocytogenes is widespread in nature being part of the faecal flora of many mammals and it is a common foodborne source. It is acquired by humans primarily through consumption of contaminated food. Besides, between 1% and 10% of the population is a faecal carrier of L.monocytogenes. Listeriosis may occur sporadically or in outbreaks. Infection causes a spectrum of illness, ranging from febrile gastroenteritis to invasive disease, including bacteraemia, sepsis, and meningoencephalitis. This infection has a low incidence, although it is undeniably increasing, particularly due to the rise of population of over 60 years old or of under 60 years olds with a predisposing condition. The diagnosis is complicated because of its incubation period and the different clinical manifestations. Also listeriosis has a high mortality despite adequate and early treatment. The importance of bacteraemia for L. monocytogenes lies in the infrequency of this bacterium and the high mortality, even with appropriate antibiotic treatment. PMID:24822197
Attentional Disengagement in Adults with Williams syndrome
Lense, Miriam D.; Key, Alexandra P.; Dykens, Elisabeth M.
2011-01-01
Williams syndrome (WS) is a neurodevelopmental disorder characterized by a distinctive behavioral and cognitive profile, including widespread problems with attention. However, the specific nature of their attentional difficulties, such as inappropriate attentional allocation and/or poor attentional disengagement abilities, has yet to be elucidated. Furthermore, it is unknown if there is an underlying difficulty with the temporal dynamics of attention in WS or if their attentional difficulties are task-dependent, because previous studies have examined attention in established areas of deficit and atypicality (specifically, visuospatial and face processing). In this study, we examined attentional processing in 14 adults with WS (20-59 years) and 17 typically developing controls (19-39 years) using an attentional blink (AB) paradigm. The AB is the decreased ability to detect a second target when it is presented in close proximity to an initial target. Overall, adults with WS had an AB that was prolonged in duration, but no different in magnitude, compared with typically developing control participants. AB performance was not explained by IQ, working memory, or processing speed in either group. Thus, results suggest that the attention problems in WS are primarily due to general attentional disengagement difficulties rather than inappropriate attentional allocation. PMID:21885176
A review of methods for the chemical characterization of cannabis natural products.
Leghissa, Allegra; Hildenbrand, Zacariah L; Schug, Kevin A
2018-01-01
Cannabis has garnered a great deal of new attention in the past couple of years in the United States due to the increasing instances of its legalization for recreational use and indications for medicinal benefit. Despite a growing number of laboratories focused on cannabis analysis, the separation science literature pertaining to the determination of cannabis natural products is still in its infancy despite the plant having been utilized by humans for nearly 30 000 years and it being now the most widely used drug worldwide. This is largely attributable to the restrictions associated with cannabis as it is characterized as a schedule 1 drug in the United States. Presented here are reviewed analytical methods for the determination of cannabinoids (primarily) and terpenes (secondarily), the primary natural products of interest in cannabis plants. Focus is placed foremost on analyses from plant extracts and the various instrumentation and techniques that are used, but some coverage is also given to analysis of cannabinoid metabolites found in biological fluids. The goal of this work is to provide a collection of relevant separation science information, upon which the field of cannabis analysis can continue to grow. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Rural settlements dynamics and the prospects of densification strategy in rural Bangladesh.
Alam, A F M Ashraful; Asad, Rumana; Enamul Kabir, Md
2016-01-01
Given the year on year decrease of rural farmland and various forms of land degradation through the intrusion of non-farm land uses, the government of Bangladesh has drafted the agrarian reform strategies, primarily to protect the agricultural land from encroachment, conversion, and indiscriminate use. The draft Agricultural Land Protection and Land Use Bill since its inception in 2011 is facing serious uncertainties of implementation due to its borrowed nature from the developed contexts and inadequacy to recognize the local complexities. With a particular focus on the densification component of the draft bill, a semester-long design studio was conducted in consultation with the existing villagers to explore the practicability of the draft bill in the villages of Tetultala and Chhoygharia in the south-western coastal Bangladesh. The findings from the two villages hint that in Bangladesh, the unique and evolving nature of rural settlements dynamics that are disintegrating the rural society from farming practices and the farmland, thereby, unsettling the traditional village-morphology. The settlements dynamics vary from those of the western context; hence, there is an emerging need to build locally situated knowledge towards a feasible rural land reform.
Posterior chamber lens implantation with scleral fixation in children with traumatic cataract.
Caca, Ihsan; Sahin, Alparslan; Ari, Seyhmus; Alakus, Fuat
2011-01-01
To evaluate the outcomes of posterior chamber lens implantation with scleral fixation (SF-PCIOL) in children with traumatic cataract. Twenty-four eyes of 24 cases were included. All patients had corneal or corneoscleral lacerations that were primarily repaired. Traumatic cataract subsequently developed and SF-PCIOL was performed due to insufficient posterior capsule support. The average age of the patients was 5.8 years (range: 4 to 10 years). All cases had SF-PCIOL implanted via internal route using triangular double scleral flaps made of 9-0 polypropylene after a complete anterior vitrectomy. Average follow-up was 14.6 ± 4.3 months (range: 11 to 18 months). Visual acuity was increased at the last visit in 23 (96%) patients. Common postoperative complications were fibrinous reaction in 6 (25%) patients, transient intraocular pressure increase in 4 (17%) patients, membrane formation requiring removal in 1 (4%) patient, transient intraocular hemorrhage as vitreous hemorrhage in 1 (4%) patient, and retinal detachment in 1 (4%) patient after the postoperative second month. SF-PCIOL is an effective and reliable method in patients with pediatric traumatic cataract who had insufficient posterior capsule support. Copyright 2011, SLACK Incorporated.
Musculoskeletal trauma services in Uganda.
Naddumba, E K
2008-10-01
Approximately 2000 lives are lost in Uganda annually through road traffic accidents. In Kampala, they account for 39% of all injuries, primarily in males aged 16-44 years. They are a result of rapid motorization and urbanization in a country with a poor economy. Uganda's population is an estimated 28 million with a growth rate of 3.4% per year. Motorcycles and omnibuses, the main taxi vehicles, are the primary contributors to the accidents. Poor roads and drivers compound the situation. Twenty-three orthopaedic surgeons (one for every 1,300,000 people) provide specialist services that are available only at three regional hospitals and the National Referral Hospital in Kampala. The majority of musculoskeletal injuries are managed nonoperatively by 200 orthopaedic officers distributed at the district, regional and national referral hospitals. Because of the poor economy, 9% of the national budget is allocated to the health sector. Patients with musculoskeletal injuries in Uganda frequently fail to receive immediate care due to inadequate resources and most are treated by traditional bonesetters. Neglected injuries typically result in poor outcomes. Possible solutions include a public health approach for prevention of road traffic injuries, training of adequate human resources, and infrastructure development.
Advances and Environmental Conditions of Spring Migration Phenology of American White Pelicans.
King, D Tommy; Wang, Guiming; Yang, Zhiqiang; Fischer, Justin W
2017-01-16
Spring migration phenology of birds has advanced under warming climate. Migration timing of short-distance migrants is believed to be responsive to environmental changes primarily under exogenous control. However, understanding the ecological causes of the advancement in avian spring migration phenology is still a challenge due to the lack of long-term precise location data. We used 11 years of Global Positioning System relocation data to determine four different migration dates of the annual migration cycle of the American white pelican (Pelecanus erythrorhynchos), a short-distance migrant. We also tested the hypothesis that increases in winter temperature and precipitation on the wintering grounds would advance pelican spring migration. Pelican spring departures and arrivals advanced steadily from 2002 to 2011. Spring departure timing exhibited high repeatability at the upper end of migration timing repeatability reported in literature. However, individual spring departure and arrival dates were not related to winter daily temperature, total winter precipitation, and detrended vegetation green-up dates indexed by the normalized difference vegetation index. Despite high repeatability, the observed between-year variation of spring departure dates was still sufficient for the advancement of spring departure timing.
Ceramic Composite Development for Gas Turbine Engine Hot Section Components
NASA Technical Reports Server (NTRS)
DiCarlo, James A.; VANrOODE, mARK
2006-01-01
The development of ceramic materials for incorporation into the hot section of gas turbine engines has been ongoing for about fifty years. Researchers have designed, developed, and tested ceramic gas turbine components in rigs and engines for automotive, aero-propulsion, industrial, and utility power applications. Today, primarily because of materials limitations and/or economic factors, major challenges still remain for the implementation of ceramic components in gas turbines. For example, because of low fracture toughness, monolithic ceramics continue to suffer from the risk of failure due to unknown extrinsic damage events during engine service. On the other hand, ceramic matrix composites (CMC) with their ability to display much higher damage tolerance appear to be the materials of choice for current and future engine components. The objective of this paper is to briefly review the design and property status of CMC materials for implementation within the combustor and turbine sections for gas turbine engine applications. It is shown that although CMC systems have advanced significantly in thermo-structural performance within recent years, certain challenges still exist in terms of producibility, design, and affordability for commercial CMC turbine components. Nevertheless, there exist some recent successful efforts for prototype CMC components within different engine types.
Slotved, Hans-Christian; Dalby, Tine; Hoffmann, Steen
2016-02-03
Surveillance data on invasive pneumococcal disease (IPD) in Denmark (1999-2014) was analysed regarding the incidence and age-distribution due to ten selected non-PCV serotypes (10-Non-PCV). The effect of PCV-7 and PCV-13 vaccines on the 10-Non-PCV IPD incidence was examined. IPD cases caused by serotypes included in PCV-7, the additional six serotypes included in PCV-13 and 10-Non-PCV serotypes were identified (8, 9N, 11A, 12F, 15A, 22F, 24F, 20, 23B, 33F). The IPD incidence was stratified by three age groups: 0-4 years, 5-64 years and 65+ years. The predominant IPD cases were caused by serotypes that are not included in PCV-13 (71%), followed by the six additional PCV-13 serotypes. The IPD incidence of serotypes included in the PCV-7 decreased markedly after PCV-7 introduction but are still diagnosed at a low level. The IPD incidence for the 10-Non-PCV serotypes was low for age groups 0-4 years and 5-64 years but high for 65+ years. Future vaccinations of the young age group alone with a vaccine targeting some of the 10-Non-PCV serotypes may not elicit the desired effect on herd protection since these serotypes are primarily causing IPD among the elderly. Future pneumococcal vaccination strategies in Denmark may therefore need carriage studies in order to identify among whom the pneumococcal serotypes causing IPD are carried. Copyright © 2016 Elsevier Ltd. All rights reserved.
High rate of translocation-based gene birth on the Drosophila Y chromosome.
Tobler, Ray; Nolte, Viola; Schlötterer, Christian
2017-10-31
The Y chromosome is a unique genetic environment defined by a lack of recombination and male-limited inheritance. The Drosophila Y chromosome has been gradually acquiring genes from the rest of the genome, with only seven Y-linked genes being gained over the past 63 million years (0.12 gene gains per million years). Using a next-generation sequencing (NGS)-powered genomic scan, we show that gene transfers to the Y chromosome are much more common than previously suspected: at least 25 have arisen across three Drosophila species over the past 5.4 million years (1.67 per million years for each lineage). The gene transfer rate is significantly lower in Drosophila melanogaster than in the Drosophila simulans clade, primarily due to Y-linked retrotranspositions being significantly more common in the latter. Despite all Y-linked gene transfers being evolutionarily recent (<1 million years old), only three showed evidence for purifying selection ( ω ≤ 0.14). Thus, although the resulting Y-linked functional gene acquisition rate (0.25 new genes per million years) is double the longer-term estimate, the fate of most new Y-linked genes is defined by rapid degeneration and pseudogenization. Our results show that Y-linked gene traffic, and the molecular mechanisms governing these transfers, can diverge rapidly between species, revealing the Drosophila Y chromosome to be more dynamic than previously appreciated. Our analytical method provides a powerful means to identify Y-linked gene transfers and will help illuminate the evolutionary dynamics of the Y chromosome in Drosophila and other species. Copyright © 2017 the Author(s). Published by PNAS.
Trust and Deception in Children with Autism Spectrum Disorders: A Social Learning Perspective.
Yang, Yiying; Tian, Yuan; Fang, Jing; Lu, Haoyang; Wei, Kunlin; Yi, Li
2017-03-01
Previous research has demonstrated abnormal trust and deception behaviors in children with Autism Spectrum Disorders (ASD), and we aimed to examine whether these abnormalities were primarily due to their specific deficits in social learning. We tested 42 high-functioning children with ASD and 38 age- and ability-matched typically developing (TD) children in trust and deception tasks and a novel condition with reduced social components. Results indicated that while TD children improved their performance with more social components, children with ASD lacked this additional performance gain, though they performed similarly as TD children in the condition with reduced social components. Our findings highlight that deficits of ASD in trust and deception are primarily associated with failure of use of social cues.
SIG Galileo final converter technical summary report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hinderman, J.D.
1979-05-01
The report is primarily concerned with the work performed for DOE on converter development and fabrication for the NASA Galileo Jupiter mission as a DOE prime contractor with interface primarily with Teledyne Energy Systems. The activities reported on were directed toward design, analysis and testing of modules and converters SN-1 thru SN-7 and attendant Quality Control and Reliability effort. Although assembly and testing of SN-1 was not accomplished due to the stop work order, the design was virtually completed and a significant amount of subcontracting and manufacturing of both module and converter components was underway. These subcontracting and manufacturing activitiesmore » were selectively closed down depending upon degree of completion and material or hardware potential usage in the Technology Program.« less
Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50-59 years.
Schmader, Kenneth E; Levin, Myron J; Gnann, John W; McNeil, Shelly A; Vesikari, Timo; Betts, Robert F; Keay, Susan; Stek, Jon E; Bundick, Nickoya D; Su, Shu-Chih; Zhao, Yanli; Li, Xiaoming; Chan, Ivan S F; Annunziato, Paula W; Parrino, Janie
2012-04-01
Herpes zoster (HZ) adversely affects individuals aged 50-59, but vaccine efficacy has not been assessed in this population. This study was designed to determine the efficacy, safety, and tolerability of zoster vaccine for preventing HZ in persons aged 50-59 years. This was a randomized, double-blind, placebo-controlled study of 22 439 subjects aged 50-59 years conducted in North America and Europe. Subjects were given 1 dose of licensed zoster vaccine (ZV) (Zostavax; Merck) and followed for occurrence of HZ for ≥1 year (mean, 1.3 years) postvaccination until accrual of ≥96 confirmed HZ cases (as determined by testing lesions swabs for varicella zoster virus DNA by polymerase chain reaction). Subjects were followed for all adverse events (AEs) from day 1 to day 42 postvaccination and for serious AEs (SAEs) through day 182 postvaccination. The ZV reduced the incidence of HZ (30 cases in vaccine group, 1.99/1000 person-years vs 99 cases in placebo group, 6.57/1000 person-years). Vaccine efficacy for preventing HZ was 69.8% (95% confidence interval, 54.1-80.6). AEs were reported by 72.8% of subjects in the ZV group and 41.5% in the placebo group, with the difference primarily due to higher rates of injection-site AEs and headache. The proportion of subjects reporting SAEs occurring within 42 days postvaccination (ZV, 0.6%; placebo, 0.5%) and 182 days postvaccination (ZV, 2.1%; placebo, 1.9%) was similar between groups. In subjects aged 50-59 years, the ZV significantly reduced the incidence of HZ and was well tolerated. NCT00534248.
Effects of electrofishing gear type on spatial and temporal variability in fish community sampling
Meador, M.R.; McIntyre, J.P.
2003-01-01
Fish community data collected from 24 major river basins between 1993 and 1998 as part of the U.S. Geological Survey's National Water-Quality Assessment Program were analyzed to assess multiple-reach (three consecutive reaches) and multiple-year (three consecutive years) variability in samples collected at a site. Variability was assessed using the coefficient of variation (CV; SD/mean) of species richness, the Jaccard index (JI), and the percent similarity index (PSI). Data were categorized by three electrofishing sample collection methods: backpack, towed barge, and boat. Overall, multiple-reach CV values were significantly lower than those for multiple years, whereas multiple-reach JI and PSI values were significantly greater than those for multiple years. Multiple-reach and multiple-year CV values did not vary significantly among electrofishing methods, although JI and PSI values were significantly greatest for backpack electrofishing across multiple reaches and multiple years. The absolute difference between mean species richness for multiple-reach samples and mean species richness for multiple-year samples was 0.8 species (9.5% of total species richness) for backpack samples, 1.7 species (10.1%) for towed-barge samples, and 4.5 species (24.4%) for boat-collected samples. Review of boat-collected fish samples indicated that representatives of four taxonomic families - Catostomidae, Centrarchidae, Cyprinidae, and Ictaluridae - were collected at all sites. Of these, catostomids exhibited greater interannual variability than centrarchids, cyprinids, or ictalurids. Caution should be exercised when combining boat-collected fish community data from different years because of relatively high interannual variability, which is primarily due to certain relatively mobile species. Such variability may obscure longer-term trends.
ERIC Educational Resources Information Center
Bilson, Barbara, Ed.; Kurilich, Frances, Ed.
1979-01-01
Designed primarily for English faculty at two-year colleges in California, "Inside English" includes articles on instructional innovations and major curricular, administrative, and employment issues of concern to teachers in the field as well as information on the activities of the English Council of the California Two-Year Colleges (ECCTYC). The…
Visible-Light Responsive Catalysts Using Quantum Dot-Modified TiO2 for Air and Water Purification
NASA Technical Reports Server (NTRS)
Coutts, Janelle L.; Hintze, Paul E.; Clausen, Christian A.; Richards, Jeffrey T.
2014-01-01
Photocatalysis, the oxidation or reduction of contaminants by light-activated catalysts, utilizing titanium dioxide (TiO2) as the catalytic substrate has been widely studied for trace contaminant control in both air and water applications. The interest in this process is due primarily to its low energy consumption and capacity for catalyst regeneration. Titanium dioxide requires ultraviolet light for activation due to its relatively large band gap energy of 3.2 eV. Traditionally, Hg-vapor fluorescent light sources are used in PCO reactors; however, the use of mercury precludes the use of this PCO technology in a spaceflight environment due to concerns over crew Hg exposure.
First Footing Inter-Faith Dialogue
ERIC Educational Resources Information Center
Luby, Antony
2014-01-01
This article examines an action research project on inter-faith dialogue within the sensitive context of Catholic pupils being taught Catholic religious education in state-funded secondary schools. Twenty pupils in S3 and S4 (Year 10 and Year 11) participated in a series of three paired conversations that focused primarily on science and religion,…
So What Now? Practical Strategies for Shifting the Cost Conversation
ERIC Educational Resources Information Center
Delta Project on Postsecondary Education Costs, Productivity and Accountability, 2012
2012-01-01
Policy discussions about funding in higher education focus primarily on revenues needed to balance budgets from year to year, rather than on how funds need to be invested to meet strategic priorities. The data in "Trends" show that the incremental approach to fundraising and spending has resulted in a slow disinvestment in core…
Guidance and Counseling Personnel and Programs in Nevada.
ERIC Educational Resources Information Center
Nevada Univ., Reno. Research and Educational Planning Center.
Data were collected on guidance and counseling programs and guidance personnel in Nevada schools. Questionnaires were mailed to all 309 practicing school counselors in Nevada; the response rate was 72%. Guidance counselors in Nevada were primarily female, Caucasian, and middle-aged. Mean number of years as a counselor was 9 years, and most…
Horizons: A Guide to Post-Secondary Education in Ontario, 1983-84. Revised.
ERIC Educational Resources Information Center
Ontario Ministry of Colleges and Universities, Toronto.
Information is presented on offerings and student costs at colleges of applied arts and technology in Ontario, Canada. These colleges are comprehensive institutions offering primarily diploma programs (2-3 years), and certificate programs (less than 1 year). Credit courses leading toward a diploma may be offered through continuing education on a…
Alternative Fuels Data Center: State Alternative Fuel and Advanced Vehicle
2017, the number of new state-level legislative, executive, private, and utility activities related to 2016 (54 total), but in line with previous years. The analysis below provides detail on trends in new (PEVs). Also consistent with recent prior years, new utility and private incentives primarily addressed
Oakton Community College Comprehensive Annual Financial Report, Fiscal Year Ended June 30, 1996.
ERIC Educational Resources Information Center
Hilquist, David E.
Consisting primarily of tables, this report provides financial data on Oakton Community College in Illinois for the fiscal year ending on June 30, 1996. This comprehensive annual financial report consists of an introductory section, financial section, statistical section, and special reports section. The introductory section includes a transmittal…
The Year in Forestry Fiscal Year 2006
Northeastern Area
2006-01-01
The Northeastern Area State and Private Forestry is a major unit of the Forest Service, U.S. Department of Agriculture. The Northeastern Area works in partnership with State forestry agencies and others to promote the wise management, protection, and sustainable use of urban and rural forest resources, primarily on non-Federal lands. Most often, specialists provide...
Annual Report: Discipline, Crime, and Violence, School Year 2008-2009
ERIC Educational Resources Information Center
Virginia Department of Education, 2011
2011-01-01
The "Code of Virginia" requires school divisions statewide to submit data to the Virginia Department of Education (VDOE) on incidents of discipline, crime, and violence (DCV). School divisions began reporting such data in 1991. This annual report focuses primarily on DCV data submitted for school year 2008-2009, with selected comparisons…
Annual Report: Discipline, Crime, and Violence, School Year 2009-2010
ERIC Educational Resources Information Center
Virginia Department of Education, 2011
2011-01-01
The "Code of Virginia" requires school divisions statewide to submit data to the Virginia Department of Education (VDOE) on incidents of discipline, crime, and violence (DCV). School divisions began reporting such data in 1991. This annual report focuses primarily on DCV data submitted for school year 2009-2010, with selected comparisons…
A history of the Florence Nightingale International Foundation.
Beck, F S
1989-01-01
For 55 years the Florence Nightingale International Foundation (FNIF) has been associated with ICN. Although it has changed in form over the years, its content and focus--primarily on education--have perpetuated a lasting memorial to its namesake. Below, the author, who was responsible for its early accomplishments, relates FNIF's beginnings and subsequent history.
Annual Report: Discipline, Crime, and Violence, School Year 2007-2008
ERIC Educational Resources Information Center
Virginia Department of Education, 2009
2009-01-01
The "Code of Virginia" requires school divisions statewide to submit data to the Virginia Department of Education (VDOE) on incidents of discipline, crime, and violence (DCV). School divisions began reporting such data in 1991. This annual report focuses primarily on DCV data submitted for school year 2007-2008, with selected comparisons…
Annual Report: Discipline, Crime, and Violence, School Year 2006-2007
ERIC Educational Resources Information Center
Virginia Department of Education, 2008
2008-01-01
The "Code of Virginia" requires school divisions statewide to submit data to the Virginia Department of Education (VDOE) on incidents of discipline, crime, and violence (DCV). School divisions began reporting such data in 1991. This annual report focuses primarily on DCV data submitted for school year 2006-2007, with selected comparisons…
DISTRIBUTION OF RESIDENTIAL ORGANOCHLORINE PESTICIDE RESIDUALS ALONG THE ARIZONA/MEXICO BORDER
The use of DDT has been banned for many years in the United States. Mexico began a 10-year phase out of DDT in 1997. DDT was banned in the U.S. primarily because of its environmental persistence. Thus, DDT is still found in the outdoor and indoor environment. We report the ...
29 CFR 4211.12 - Modifications to the presumptive, modified presumptive and rolling-5 methods.
Code of Federal Regulations, 2014 CFR
2014-07-01
... presumptive method (including a plan that primarily covers employees in the building and construction industry... the building and construction industry, the plan year designated by a plan amendment pursuant to... after the designated plan year are reduced by the value of all outstanding claims for withdrawal...
29 CFR 4211.12 - Modifications to the presumptive, modified presumptive and rolling-5 methods.
Code of Federal Regulations, 2010 CFR
2010-07-01
... presumptive method (including a plan that primarily covers employees in the building and construction industry... the building and construction industry, the plan year designated by a plan amendment pursuant to... after the designated plan year are reduced by the value of all outstanding claims for withdrawal...
29 CFR 4211.12 - Modifications to the presumptive, modified presumptive and rolling-5 methods.
Code of Federal Regulations, 2011 CFR
2011-07-01
... presumptive method (including a plan that primarily covers employees in the building and construction industry... the building and construction industry, the plan year designated by a plan amendment pursuant to... after the designated plan year are reduced by the value of all outstanding claims for withdrawal...
76 FR 75427 - Farm Loan Programs Loan Making Activities
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-02
... prior farming experience of the applicant. This amendment is required by sections 5001 and 5101 of the... years prior to the date of the application, if all prior farming occurred more than five years prior to...: (1) Is a beginning farmer or socially disadvantaged farmer engaged primarily in farming in the United...
Age-related differences in the rhythmic structure of the golf swing.
Kim, Tae Hoon; Jagacinski, Richard J; Lavender, Steven A
2011-01-01
Participants were 20 younger golfers (M age=19.8 years, SD=1.84 years) and 20 older golfers (M age=63.0 years, SD=2.55 years) who attempted 40- and 80-yard eight-iron shots requiring an adjustment of their force and timing. No age-related differences were found in the tempo or speed of the shot; however, there were differences in the rhythmic relationship between the clubhead force and the weight shift. Whereas younger golfers primarily exhibited a 3 versus 2 polyrhythmic pattern between the peak forces of the clubhead and weight shift, older golfers primarily exhibited a simpler 3 versus 3 rhythmic force pattern by adding a forward weight shift at the beginning of the shot. Additionally, older golfers exhibited less independence between the timing of the clubhead force and weight shift, which indicated greater use of a single integrated coordinative unit rather than 2 units. These findings are interpreted as compensations for age-related slowing and increased temporal variability that help to preserve tempo at a speed comparable to younger adults.
Marine mammal acoustic detections in the northeastern Chukchi Sea, September 2007-July 2011
NASA Astrophysics Data System (ADS)
Hannay, David E.; Delarue, Julien; Mouy, Xavier; Martin, Bruce S.; Leary, Del; Oswald, Julie N.; Vallarta, Jonathan
2013-09-01
Several cetacean and pinniped species use the northeastern Chukchi Sea as seasonal or year-round habitat. This area has experienced pronounced reduction in the extent of summer sea ice over the last decade, as well as increased anthropogenic activity, particularly in the form of oil and gas exploration. The effects of these changes on marine mammal species are presently unknown. Autonomous passive acoustic recorders were deployed over a wide area of the northeastern Chukchi Sea off the coast of Alaska from Cape Lisburne to Barrow, at distances from 8 km to 200 km from shore: up to 44 each summer and up to 8 each winter. Acoustic data were acquired at 16 kHz continuously during summer and on a duty cycle of 40 or 48 min within each 4-h period during winter. Recordings were analyzed manually and using automated detection and classification systems to identify calls. Bowhead (Balaena mysticetus) and beluga (Delphinapterus leucas) whale calls were detected primarily from April through June and from September to December during their migrations between the Bering and Beaufort seas. Summer detections were rare and usually concentrated off Wainwright and Barrow, Alaska. Gray (Eschrichtius robustus) whale calls were detected between July and October, their occurrence decreasing with increasing distance from shore. Fin (Balaenoptera physalus), killer (Orcinus orca), minke (Balaenoptera acutorostrata), and humpback (Megaptera novaeangliae) whales were detected sporadically in summer and early fall. Walrus (Odobenus rosmarus) was the most commonly detected species between June and October, primarily occupying the southern edge of Hanna Shoal and haul-outs near coastal recording stations off Wainwright and Point Lay. Ringed (Pusa hispida) and bearded (Erignathus barbatus) seals occur year-round in the Chukchi Sea. Ringed seal acoustic detections occurred throughout the year but detection numbers were low, likely due to low vocalization rates. Bearded seal acoustic detections peaked in April and May during their breeding season, with much lower detection numbers in July and August, likely as a result of reduced calling rates after breeding season. Ribbon seals (Histriophoca fasciata) were only detected in the fall as they migrated south through the study area toward the Bering Sea. These results suggest a regular presence of marine mammals in the Chukchi Sea year-round, with species-dependent seasonal and spatial density variations.
Smith, Merryn G; Miller, Rebecca E; Arndt, Stefan K; Kasel, Sabine; Bennett, Lauren T
2018-04-01
Non-structural carbohydrates (NSCs) form a fundamental yet poorly quantified carbon pool in trees. Studies of NSC seasonality in forest trees have seldom measured whole-tree NSC stocks and allocation among organs, and are not representative of all tree functional types. Non-structural carbohydrate research has primarily focussed on broadleaf deciduous and coniferous evergreen trees with distinct growing seasons, while broadleaf evergreen trees remain under-studied despite their different growth phenology. We measured whole-tree NSC allocation and temporal variation in Eucalyptus obliqua L'Hér., a broadleaf evergreen tree species typically occurring in mixed-age temperate forests, which has year-round growth and the capacity to resprout after fire. Our overarching objective was to improve the empirical basis for understanding the functional importance of NSC allocation and stock changes at the tree- and organ-level in this tree functional type. Starch was the principal storage carbohydrate and was primarily stored in the stem and roots of young (14-year-old) trees rather than the lignotuber, which did not appear to be a specialized starch storage organ. Whole-tree NSC stocks were depleted during spring and summer due to significant decreases in starch mass in the roots and stem, seemingly to support root and crown growth but potentially exacerbated by water stress in summer. Seasonality of stem NSCs differed between young and mature trees, and was not synchronized with stem basal area increments in mature trees. Our results suggest that the relative magnitude of seasonal NSC stock changes could vary with tree growth stage, and that the main drivers of NSC fluctuations in broadleaf evergreen trees in temperate biomes could be periodic disturbances such as summer drought and fire, rather than growth phenology. These results have implications for understanding post-fire tree recovery via resprouting, and for incorporating NSC pools into carbon models of mixed-age forests.
Prevalence and characteristics of femoral injection among Seattle-area injection drug users.
Coffin, Phillip O; Coffin, Lara S; Murphy, Shilo; Jenkins, Lindsay M; Golden, Matthew R
2012-04-01
Injection drug use (IDU) into central veins, most common among long-term IDUs with no other options, can lead to severe infectious, vascular, and traumatic medical consequences. To follow-up on anecdotal reports of femoral vein injection and related medical problems in Seattle, we analyzed data from the annual survey of a community-based syringe exchange program. A total of 276 (81%) of 343 program attendees completed the survey in August 2010. Among 248 IDUs, 66% were male, 78% white, and 86% primarily injected opiates. One hundred respondents (40%) had injected into the femoral vein, 55% of whom were actively doing so, and 58% of whom reported medical complications that they attributed to the practice. Most (66%) used the femoral vein due to difficulty accessing other veins, although 61% reported other veins they could access and 67% reporting using other sites since initiating femoral injection. While injecting into muscle was more frequent among older IDUs with longer injection careers, the prevalence of femoral injection was highest among respondents in their late twenties with 2.5-6 years of injecting drugs. Multivariate analysis demonstrated an increased risk of initiating femoral injection each calendar year after 2007. Injecting into the femoral vein was also associated with white versus other race (odds ratio [OR] 2.7, 95% CI 1.3-5.4) and injection of primarily opiates versus other drugs (OR 6.3, 95% CI 1.2-32.9) and not associated with age, length of IDU career, or a history of injecting into muscle. These findings suggest a secular trend of increasing femoral injection among Seattle-area IDUs with a high rate of related medical problems. Interventions, such as education regarding the hazards of central venous injection and guidance on safe injection into peripheral veins, are needed to minimize the health consequences of femoral injection.
Davy, Brenda M; Jahren, A Hope; Hedrick, Valisa E; You, Wen; Zoellner, Jamie M
2017-01-01
Objective Controversy exists surrounding the health effects of added sugar (AS) and sugar-sweetened beverage (SSB) intakes, primarily due to a reliance on self-reported dietary intake. The purpose of the current investigation was to determine if a 6-month intervention targeting reduced SSB intake would impact δ13C AS intake biomarker values. Design A randomized controlled intervention trial. At baseline and at 6 months, participants underwent assessments of anthropometrics and dietary intake. Fasting fingerstick blood samples were obtained and analysed for δ13C value using natural abundance stable isotope MS. Statistical analysis included descriptive statistics, correlational analyses and multilevel mixed-effects linear regression analysis using an intention-to-treat approach. Setting Rural Southwest Virginia, USA. Subjects Adults aged ≥18 years who consumed ≥200 kcal SSB/d (≥837 kJ/d) were randomly assigned to either the intervention (n 155) or a matched-contact group (n 146). Participants (mean age 42·1 (SD 13·4) years) were primarily female and overweight (21·5 %) or obese (57·0 %). Results A significant group by time difference in δ13C value was detected (P < 0·001), with mean (SD) δ13C value decreasing in the intervention group (pre: −18·92 (0·65) ‰, post: −18·97 (0·65) ‰) and no change in the comparison group (pre: −18·94 (0·72) ‰, post: −18·92 (0·73) ‰). Significant group differences in weight and BMI change were also detected. Changes in biomarker δ13C values were consistent with changes in self-reported AS and SSB intakes. Conclusions The δ13C sugar intake biomarker assessed using fingerstick blood samples shows promise as an objective indicator of AS and SSB intakes which could be feasibly included in community-based research trials. PMID:27297740
The effect of antiresorptives on bone quality.
Recker, Robert R; Armas, Laura
2011-08-01
Currently, antiresorptive therapy in the treatment and prevention of osteoporosis includes bisphosphonates, estrogen replacement, selective estrogen receptor modulators (raloxifene), and denosumab (a human antibody that inactivates RANKL). The original paradigm driving the development of antiresorptive therapy was that inhibition of bone resorption would allow bone formation to continue and correct the defect. However, it is now clear increases in bone density account for little of the antifracture effect of these treatments. We examined the antifracture benefit of antiresorptives deriving from bone quality changes. We searched the archive of nearly 30,000 articles accumulated over more than 40 years in our research center library using a software program (Refman™). Approximately 250 publications were identified in locating the 69 cited here. The findings document antiresorptive agents are not primarily anabolic. All cause a modest increase in bone density due to a reduction in the bone remodeling space; however, the majority of their efficacy is due to suppression of the primary cause of osteoporosis, ie, excessive bone remodeling not driven by mechanical need. All of them improve some element(s) of bone quality. Antiresorptive therapy reduces risk of fracture by improving bone quality through halting removal of bone tissue and the resultant destruction of microarchitecture of bone and, perhaps to some extent, by improving the intrinsic material properties of bone tissue. Information presented here may help clinicians to improve selection of patients for antiresorptive therapy by avoiding them in cases clearly not due to excessive bone remodeling.
Mesoamerican Nephropathy or Global Warming Nephropathy?
Roncal-Jimenez, Carlos A; García-Trabanino, Ramon; Wesseling, Catharina; Johnson, Richard J
2016-01-01
An epidemic of chronic kidney disease (CKD) of unknown cause has emerged along the Pacific Coast of Central America. The disease primarily affects men working manually outdoors, and the major group affected is sugarcane workers. The disease presents with an asymptomatic rise in serum creatinine that progresses to end-stage renal disease over several years. Renal biopsies show chronic tubulointerstitial disease. While the cause remains unknown, recent studies suggest that it is driven by recurrent dehydration in the hot climate. Potential mechanisms include the development of hyperosmolarity with the activation of the aldose reductase-fructokinase pathway in the proximal tubule leading to local injury and inflammation, and the possibility that renal injury may be the consequence of repeated uricosuria and urate crystal formation as a consequence of both increased generation and urinary concentration, similar to a chronic tumor lysis syndrome. The epidemic is postulated to be increasing due to the effects of global warming. An epidemic of CKD has led to the death of more than 20,000 lives in Central America. The cause is unknown, but appears to be due to recurrent dehydration. Potential mechanisms for injury are renal damage as a consequence of recurrent hyperosmolarity and/or injury to the tubules from repeated episodes of uricosuria. The epidemic of CKD in Mesoamerica may be due to chronic recurrent dehydration as a consequence of global warming and working conditions. This entity may be one of the first major diseases attributed to climate change and the greenhouse effect. © 2016 S. Karger AG, Basel.
[The history of polio in Sweden - from infantile paralysis to polio vaccine].
Axelsson, Per
2004-01-01
Although other epidemics declined due to improved hygiene and sanitation, legislation, and vaccination, polio epidemics appeared in Sweden in 1881 and at the turn of the 20th century the disease became and annual feature in the Swedish epidemiological pattern. Due to the vaccination starting in 1957 epidemics ceased to exist in Sweden around 1965. This article deals with the history polio epidemics in Sweden, 1880-1965 and gives a brief description of: the demographical influence of polio, how did the medical authorities investigate and try to combat it, and the different comprehensions of how polio affected its victims.A study of polio incidence in Sweden at the national level during 1905-1962 reveals that the disease caused major epidemics in 1911-1913 and 1953. At the beginning of the 20th century polio primarily attacked children up to 10 years of age, and at the end of the period victims were represented in all age groups, but mainly in the ages 20-39. Due to its enigmatic appearance, polio was not considered as an epidemic infectious disease during the 19th century. Sweden's early epidemics enabled Swedish medical science to act and together with American research institutes it acquired a leading role in international medical research on the disease. In the 1955 Jonas Salk produced the first successful vaccine against polio but also Sweden developed its own vaccine, different in choice of methods and materials from the widely used Salk-vaccine.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-09
... speed limit is proposed because there have been numerous accidents along the main access/canyon road in Zone 1. These accidents have primarily been a result of excess speed due to no posted or enforceable..., or irritant gas device. Motor vehicle includes, but is not limited to, automobiles, motorcycles, all...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-08
.... Simplot, a phosphate fertilizer manufacturing facility which is 86 km from Craters of the Moon National... any type is primarily due to emissions of organic carbon and elemental carbon, and to a lesser extent... organic carbon emissions in 2018 from natural fires compared to 4,100 tons from anthropogenic fires. With...
USDA-ARS?s Scientific Manuscript database
Container-grown nursery crops in the Southeastern United States are typically grown in a rooting substrate comprised primarily of the ground bark of pine trees. However pine bark is becoming less available and more costly due to changes in production and marketed practices within Southeastern pine f...
Hypotheses for common persimmon stand development in mixed-species bottomland hardwood forests
Brian Roy Lockhart
2013-01-01
Common persimmon (Diospyros virginiana L.) is a shade-tolerant tree species found in southern bottomland hardwood forests. It is a desired species due primarily to its large fruit used by many wildlife species. While it has been observed as a component in natural reproduction, persimmon is rarely found as an overstory species in maturing bottomland...
Free to Be...You and Me: Gender, Identity, and Education in Urban Schools
ERIC Educational Resources Information Center
Brown, Cory Terrell
2012-01-01
The Title IX legislation of 1972 was established to promote gender equity among public entities (primarily schools) that utilize federal funding to support and sustain their operation. However, the United States (U.S.) Government developed new regulations for Title IX due to No Child Left Behind (NCLB). This change allowed public school districts…
POPULATION DECLINES OF THE PUERTO RICAN VIREO IN GUANICA FOREST.
JOHN FAABORG; KATE M. DUGGER; WAYNE J. ARENDT; BETHANY L. WOODWORTH; MICHAEL E. BALTZ
1997-01-01
Abundance of the Puerto Rican Vireo (Vireo Zutimeri) in Guanica Forest, Puerto Rico, has declined gradually over the period 1973-1996 as determined by constant effort mist netting. Concurrent studies of breeding vireos show low nesting success, primarily due to parasitism by Shiny Cowbirds (Molothrus bonariensis). This decline may reflect the rather recent entry of the...
Shifts in Student Motivation during Usage of a Multi-User Virtual Environment for Ecosystem Science
ERIC Educational Resources Information Center
Metcalf, Shari; Chen, Jason; Kamarainen, Amy; Frumin, Kim; Vickrey, Trisha; Grotzer, Tina; Dede, Chris
2014-01-01
In incorporating technology in science education, some have expressed concern that the value added by technology is primarily due to the novelty or excitement about using the devices, resulting in no lasting effect on student motivation or learning in science. This research addresses this concern through evaluation of student motivation during a…
ERIC Educational Resources Information Center
Dietze, Stefan; Gugliotta, Alessio; Domingue, John
2009-01-01
Current E-Learning technologies primarily follow a data and metadata-centric paradigm by providing the learner with composite content containing the learning resources and the learning process description, usually based on specific metadata standards such as ADL SCORM or IMS Learning Design. Due to the design-time binding of learning resources,…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-03
..., Global Business Travel Association (GBTA), McAfee & Taft P.C. (a law firm), and Patton Boggs LLP (a law... complete information, due primarily to concerns of the National Business Aviation Association (NBAA) to... business according to a published listing of service and schedule, general aviation operators do not. It is...
Differences in Computed Individual-Tree Volumes Caused by Differences in Field Measurements
James A. Westfall
2008-01-01
Individual-tree volumes are primarily predicted using volume equations that rely on measured tree attributes. In the northeastern United States, the Forest Inventory and Analysis program determines tree volume using dbh, bole height, proportion of cull, and species information. These measurements are subject to variability due to a host of factors. The sensitivity of...
USDA-ARS?s Scientific Manuscript database
The Chesapeake Bay (CB) is the largest and most productive estuary in the United States (US). Despite significant restoration efforts, the health of the Bay has continued to deteriorate, primarily due to excessive nutrient and sediment loadings from agricultural land. The water quality problem is ex...
ERIC Educational Resources Information Center
Olson, Joann S.; Kim, Junghwan; Hwang, Jihee
2017-01-01
This article explores the workplace learning experiences of professional staff at a small private college who changed jobs, primarily due to a departmental reorganization. In many cases, the emerging jobs were ill-defined, and participants found it challenging to be released from the responsibilities of their previous positions. A…
ERIC Educational Resources Information Center
Sumida, Anna Y.; Meyer, Meleanna A.
2006-01-01
Educational practice has focused primarily upon a transmission model of education dealing with dominant, mainstream, western ideology. This model often alienates student learners due to the absence of cultural relevance. This article focuses on a theoretical framework teachers in Hawaii are using to become transformative practitioners who promote…
Testing tree seeds for vigor: a review
F.T. Bonner
1998-01-01
This review examines the use of vigor tests for tree seeds. It suggests that precise evaluations of these tests and their application with seeds of woody plants is not yet possible. This is due to the wide genetic variation, primarily manifested in variable maturity and dormancy, that exists in most tree seed lots. Sensitive measurements of germination rate during...
Aberrant expression of liver microRNA in chickens infected with subgroup J avian leukosis virus
USDA-ARS?s Scientific Manuscript database
Subgroup J avian leukosis virus (ALV-J) is an oncogenic retrovirus primarily causing myeloid leukosis (ML) in broilers. Although ALV is well under control in a few countries including the U.S.A., poultry industry in many parts of the world continues suffering from serious economic loss due to sporad...
USDA-ARS?s Scientific Manuscript database
Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins (ACDMPV) is a developmental disorder of the lungs, primarily affecting their vasculature. FOXF1 haploinsufficiency due to heterozygous genomic deletions and point mutations have been reported in most patients with ACDMPV. The majority...
ERIC Educational Resources Information Center
Abu-Tineh, Abdullah
2013-01-01
Senior leadership positions in Jordanian Ministry of Education are held predominantly by men. Women are teachers and/or school principals. This under-representation of women is primarily due to culturally derived stereotypes that see women as teachers or school principals, but not as superintendents. The purpose of this study was to investigate,…
ERIC Educational Resources Information Center
Traynor, Anne
2017-01-01
It has long been argued that U.S. states' differential performance on nationwide assessments may reflect differences in students' opportunity to learn the tested content that is primarily due to variation in curricular content standards, rather than in instructional quality or educational investment. To quantify the effect of differences in…
Spatio-temporal variability of hyporheic exchange through a pool-riffle-pool sequence
Frank P. Gariglio; Daniele Tonina; Charles H. Luce
2013-01-01
Stream water enters and exits the streambed sediment due to hyporheic fluxes, which stem primarily from the interaction between surface water hydraulics and streambed morphology. These fluxes sustain a rich ecotone, whose habitat quality depends on their direction and magnitude. The spatio-temporal variability of hyporheic fluxes is not well understood over several...
2016-07-31
the relatively narrow focus on Wechsler’s IQ test (WAIS-IV) – a test chosen primarily due to budget constraints. Thus, to meet the requests from the...consultants allows us to re-allocate financial resources to address the limitations of our study 7 raised by the reviewers. Jens Richardt Møllegaard
ERIC Educational Resources Information Center
Hutson, David J.
2017-01-01
While most sociology students are well prepared to think critically about inequalities involving race, gender, social class, and sexuality, the topics of body weight and health present some challenges for classroom discussion. Primarily, this is due to the body's status in contemporary society as simultaneously malleable (able to be changed) and…
L.A. Ryan; A.B. Carey
1995-01-01
The western gray squirrel (Sciurus griseus Ord, 1818) has been accorded "threatened species" status by the state of Washington. populations are small, scattered, and declining primarily due to the loss and fragmentation of suitable habitat. Western gray squirrels are closely associated with Oregon white oak (Quercus garryana...
ERIC Educational Resources Information Center
Heuston, Edward Benjamin Hull
2010-01-01
Academic learning time (ALT) has long had the theoretical underpinnings sufficient to claim a causal relationship with academic achievement, but to this point empirical evidence has been lacking. This dearth of evidence has existed primarily due to difficulties associated with operationalizing ALT in traditional educational settings. Recent…
26 CFR 25.2502-2 - Donor primarily liable for tax.
Code of Federal Regulations, 2010 CFR
2010-04-01
... extent of the value of their inheritances, bequests, devises, or distributive shares of the donor's... third party during any “calendar period” (as defined in § 25.2502-1(c)(1)) considered as made one-half... much thereof as may remain due and unpaid. As used in such section 3467, the word “debt” includes a...
Harmonizing estimates of forest land area from national-level forest inventory and satellite imagery
Bonnie Ruefenacht; Mark D. Nelson; Mark Finco
2009-01-01
Estimates of forest land area are derived both from national-level forest inventories and satellite image-based map products. These estimates can differ substantially within subregional extents (e.g., states or provinces) primarily due to differences in definitions of forest land between inventory- and image-based approaches. We present a geospatial modeling approach...
Biogenic Magnetite Formation through Anaerobic Biooxidation of Fe(II)
Chaudhuri, Swades K.; Lack, Joseph G.; Coates, John D.
2001-01-01
The presence of isotopically light carbonates in association with fine-grained magnetite is considered to be primarily due to the reduction of Fe(III) by Fe(III)-reducing bacteria in the environment. Here, we report on magnetite formation by biooxidation of Fe(II) coupled to denitrification. This metabolism offers an alternative environmental source of biogenic magnetite. PMID:11375205
United States housing, second quarter 2013
Delton Alderman
2017-01-01
The U.S. housing marketâs quarter two results were disap¬pointing compared with the first quarter. Although overall expected gains did not materialize, certain sectors improved slightly. Housing under construction, completions, and new and existing home sales exhibited slight increases. Overall permit data declined, and the decrease in starts was due primarily to a...
Trust and Deception in Children with Autism Spectrum Disorders: A Social Learning Perspective
ERIC Educational Resources Information Center
Yang, Yiying; Tian, Yuan; Fang, Jing; Lu, Haoyang; Wei, Kunlin; Yi, Li
2017-01-01
Previous research has demonstrated abnormal trust and deception behaviors in children with Autism Spectrum Disorders (ASD), and we aimed to examine whether these abnormalities were primarily due to their specific deficits in social learning. We tested 42 high-functioning children with ASD and 38 age- and ability-matched typically developing (TD)…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-05
... by habitat loss due primarily to residential development and recreational encroachment (Big Wildlife... Great Basin ecosystem (Big Wildlife and NoBearHuntNV.org 2011, p. 13). The petition asserts that loss of... hair) from two American black bear populations: Lake Tahoe Basin, Nevada, and Yosemite National Park...
Thomas E. Olson; M. Violet Gray
1989-01-01
Due primarily to alteration of riparian vegetation and nest parasitism by brown-headed cowbirds (Molothrus ater), the least Bell's vireo (Vireo bellii pusillus) has under-gone a tremendous decline in range and numbers since the 1920's. In 1987, we sampled vegetation at 32 nest sites to characterize nesting habitat of...
ERIC Educational Resources Information Center
Kustusch, Mary Bridget
2016-01-01
Students in introductory physics struggle with vector algebra and these challenges are often associated with contextual and representational features of the problems. Performance on problems about cross product direction is particularly poor and some research suggests that this may be primarily due to misapplied right-hand rules. However, few…
USDA-ARS?s Scientific Manuscript database
Yield reduction and reduced crop vigor, resulting from soil acidification, are of increasing concern in eastern Washington and northern Idaho. In this region, soil pH has been decreasing at an accelerated rate, primarily due to the long-term use of ammonium based fertilizers. In no-till systems, the...
Positive Emotion in Nature as a Precursor to Learning
ERIC Educational Resources Information Center
Coleman, Tamara Chase
2014-01-01
This study was designed to examine the perception of learning in adults generated by the effect of a positive emotion-in this case, awe. For the study, a working definition of awe is an "impact-provoking reverence due to a powerful, positive emotional response to the natural world." This qualitative study used primarily face-to-face…
Effect of Hearing Loss on Peer Victimization in School-Age Children
ERIC Educational Resources Information Center
Warner-Czyz, Andrea D.; Loy, Betty; Pourchot, Hannah; White, Trissan; Cokely, Elika
2018-01-01
Nearly one third of school-age children report being bullied, primarily enduring teasing or rumors. Children with hearing loss (HL) are at increased risk of victimization due to being "different" from the general population. This project assesses effects of auditory status on bullying by comparing incidence and type of bullying in 87…
A temporal study of urban development for the municipality of Anchorage, Alaska
Markon, Carl J.
2003-01-01
A land use/land cover database was produced for a portion of the Municipality of Anchorage, Alaska to document the temporal and spatial extent of urbanization to assist in the analysis of changes in impervious cover and water quality. Data were derived from black and white and color infrared aerial photography, and satellite imagery from the early 1970's to 2000 in roughly ten‐year increments. Aerial photographs and satellite data were manually interpreted to identify and map land use/land cover classes which were then entered into a geographic information system, attributed, and georeferenced to a U.S. Geological Survey topographic map base. The spatial extent of the study was 31,117 hectares. In the early 1970's, approximately 7,356 hectares (24%) of the study area were mapped as urban developed. During the 30‐year analysis period, the largest increase in urban development occurred between the late 1970's and early 1980's when urban area increased to 12,263 hectares (39%). Between 1980 and 1990, and 1990 and 2000, urban area increased to 12,762 hectares (41%), and 13,980 hectares (45%) respectively. Most development occurred in forested or tall shrub areas, although some also occurred in wetlands. Between 1970 and 2000, close to 1,300 hectares of wetlands were lost due to development. Contrary to this, the amount of lake and pond area increased slightly from 261 hectares in 1973 to 334 hectares in 1980, and reduced to 310 hectares by 2000. The increase was primarily due to the filling in of gravel pits with spring melt water.
Patterns and sources of personality development in old age.
Kandler, Christian; Kornadt, Anna E; Hagemeyer, Birk; Neyer, Franz J
2015-07-01
Despite abundant evidence that personality development continues in adulthood, little is known about the patterns and sources of personality development in old age. We thus investigated mean-level trends and individual differences in change as well as the genetic and environmental sources of rank-order continuity and change in several personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness, perceived control, and affect intensity) and well-being. In addition, we analyzed the interrelation between perceived control and change in other personality traits as well as between change in personality traits and change in well-being. We analyzed data from older adult twins, aged 64-85 years at Time 1 (N = 410; 135 males and 275 females; 134 monozygotic and 63 dizygotic twin pairs), collected at 2 different time points about 5 years apart. On average, neuroticism increased, whereas extraversion, conscientiousness, and perceived control significantly decreased over time. Change in perceived control was associated with change in neuroticism and conscientiousness, pointing to particular adaptation mechanisms specific to old age. Whereas individual differences in personality traits were fairly stable due to both genetic and environmental sources, individual differences in change were primarily due to environmental sources (beyond random error) indicating plasticity in old age. Even though the average level of well-being did not significantly change over time, individual well-being tended to decrease with strongly increasing levels of neuroticism as well as decreasing extraversion, conscientiousness, and perceived control, indicating that personality traits predict well-being but not vice versa. We discuss implications for theory on personality development across the lifespan. (c) 2015 APA, all rights reserved).
Lewis, Jack; Rhodes, Jonathan J; Bradley, Curtis
2018-04-11
The Battle Creek watershed in northern California was historically important for its Chinook salmon populations, now at remnant levels due to land and water uses. Privately owned portions of the watershed are managed primarily for timber production, which has intensified since 1998, when clearcutting became widespread. Turbidity has been monitored by citizen volunteers at 13 locations in the watershed. Approximately 2000 grab samples were collected in the 5-year analysis period as harvesting progressed, a severe wildfire burned 11,200 ha, and most of the burned area was salvage logged. The data reveal strong associations of turbidity with the proportion of area harvested in watersheds draining to the measurement sites. Turbidity increased significantly over the measurement period in 10 watersheds and decreased at one. Some of these increases may be due to the influence of wildfire, logging roads and haul roads. However, turbidity continued trending upwards in six burned watersheds that were logged after the fire, while decreasing or remaining the same in two that escaped the fire and post-fire logging. Unusually high turbidity measurements (more than seven times the average value for a given flow condition) were very rare (0.0% of measurements) before the fire but began to appear in the first year after the fire (5.0% of measurements) and were most frequent (11.6% of measurements) in the first 9 months after salvage logging. Results suggest that harvesting contributes to road erosion and that current management practices do not fully protect water quality.
Response of barley to grasshopper defoliation in interior Alaska: dry matter and grain yield.
Begna, Sultan H; Fielding, Dennis J
2005-12-01
Barley, Hordeum vulgare L., is well adapted to subarctic Alaska growing conditions, but little is known about its response to grasshopper defoliation. A field experiment was conducted to study dry matter and grain yield in response to a combination of grasshopper defoliation and weeds in 2002 and 2003 near Delta Junction, AK (63 degrees 55' N, 145 degrees 20' W). Barley plants at third to fourth leaf stage were exposed to a combination of two levels of weeds (present or absent) and four densities of grasshoppers (equivalent to 0, 25, 50, and 75 grasshoppers per m2) of third to fourth instars of Melanoplus sanguinipes (F). Dry matter accumulation by the barley plants was determined at three times during the growing seasons: approximately 10 d after introduction of the grasshoppers, shortly after anthesis, and at maturity. Dry matter accumulation and grain yield were much lower in 2003 than in 2002, probably due to very low levels of soil moisture early in the growing season of 2003. Head clipping accounted for a greater portion of yield loss in 2003 than in 2002. The percentage of reduction in harvestable yield due to grasshoppers remained fairly constant between years (1.9 and 1.4 g per grasshopper per m2 in 2002 and 2003, respectively) despite a large difference in overall yield. Examination of the yield components suggest that yields were reduced by the early season drought in 2003 primarily through fewer seeds per head, whereas grasshoppers in both years reduced average seed weight, but not numbers of seeds.
Amyotrophic lateral sclerosis (ALS), a novel rare cause of elevated plasma troponin T levels.
Von Lueder, Thomas G; Melsom, Morten Nissen; Atar, Dan; Agewall, Stefan
2011-01-01
In this article, we report on a patient with chronic and modestly elevated plasma troponin T (TnT) levels and frequent hospitalizations following the first admission until his death one year later. The patient was initially admitted for dyspnea and discharged from hospital with a diagnosis of non-ST elevation acute myocardial infarction (AMI). Coronary angiography and echocardiography were normal, but the patient received the (false) diagnosis of AMI at two further admissions, based purely on elevated TnT. Shortly thereafter, severe respiratory failure with restrictive-type spirometry pattern became the predominant clinical symptom, with constantly elevated TnT levels at frequent re-admissions. Due to inconsistent follow-up by primarily junior and non-specialist staff at a number of different wards, pulmonary function tests and previous smoking history were mis-interpreted as typical of chronic obstructive pulmonary disease (COPD). The patient received standard COPD treatment without any improvement. After a year of gradually worsening respiratory failure and repeated hospitalizations, thorough assessment by a pulmonologist and neurologist established the final diagnosis of amyotrophic lateral sclerosis (ALS). The patient died shortly thereafter. While progressive respiratory failure is well-known to determine morbidity and mortality in patients with ALS, chronically elevated TnT levels in the absence of coronary artery disease have, to our best knowledge, not been described so far. We suggest that chronic myocardial hypoxia due to ALS-related hypoxic respiratory failure was the most likely underlying etiology for the elevated TnT levels seen here but other mechanism such as immune-mediated myocardial injury cannot be excluded.
NASA Astrophysics Data System (ADS)
Yamasaki, Mami; Aono, Mikina; Ogawa, Naoto; Tanaka, Koichiro; Imoto, Zenji; Nakamura, Yohei
2014-06-01
Evidence is accumulating that the invasion and extinction of habitat-forming seaweed species alters coastal community structure and ecological services, but their effects on the pelagic environment have been largely ignored. Thus, we examined the seasonal occurrence patterns of indigenous temperate and invasive tropical drifting algae and associated fish species every month for 2 years (2009-2011) in western Japan (Tosa Bay), where a rapid shift from temperate to tropical Sargassum species has been occurring in the coastal area since the late 1980s due to rising seawater temperatures. Of the 19 Sargassum species (31.6%) in drifting algae, we found that six were tropical species, whereas a study in the early 1980s found only one tropical species among 12 species (8.3%), thereby suggesting an increase in the proportion of tropical Sargassum species in drifting algae during the last 30 years. Drifting temperate algae were abundantly present from late winter to summer, whereas tropical algal clumps occurred primarily during summer. In the warm season, fish assemblages did not differ significantly between drifting temperate and tropical algae, suggesting the low host-algal specificity of most fishes. We also found that yellowtail juveniles frequently aggregated with drifting temperate algae from late winter to spring when drifting tropical algae were unavailable. Local fishermen collect these juveniles for use as aquaculture seed stock; therefore, the occurrence of drifting temperate algae in early spring is important for local fisheries. These results suggest that the further extinction of temperate Sargassum spp. may have negative impacts on the pelagic ecosystem and associated regional fisheries.
Meeting the future. Where will the resources for the USSR's family planning programs come from?
Laskin, M
1991-09-01
Providing resources for family planning programs in the USSR, where an extremely high rate of abortions threatens the lives of women, will require a multi-sectoral approach involving the government, international agencies, and the private sector. Every year, some 10-13 million of the USSR's 70 million women of fertile age undergo an abortion (only 7 million of the abortions every year are considered legal). A recent report indicates that only 15-18% of Soviet women have not had at least one abortion in their lifetimes. A result of the high rate of illegal abortions, morbidity and mortality affects many Soviet mothers. Additionally, infant mortality rates is as high as 58.5% in some areas of the USSR, a figure similar to that found in developing countries. Knowledge of modern contraception is high, but use remains low. This is due primarily to the lack of contraceptive availability. IUD's injectables, implants, and oral contraceptives are scarce. And even when oral contraceptives are available, few women opt for this method, due to the rampant misinformation and exaggeration concerning its side-effects. While the USSR does produce condoms, their quality is poor. Part of the solution to the lack of available contraception rests in the transition to a market economy. As the demand for these services increases, the market will begin meeting this demand. The government also has a important role to play, which includes the provision of information, medical and paramedical education, sex education, and service delivery. And international agencies will need to provide the necessary technical assistance.
NASA Technical Reports Server (NTRS)
Smith, D. F.
1985-01-01
Observations are reviewed which indicate that hard X-rays during the impulsive phase of a flare typically start with a primarily nonthermal phase which undergoes a transition to a primarily thermal phase as the flare progresses. Recent theoretical work on the modified two-stream instability as an efficient electron accelerator and modeling of thermal hard X-ray sources is considered. A scenario which is termed the dissipative thermal model is proposed to explain the observations. Fast tearing modes occurring in a loop give rise to cross-field ion motion. This in turn excites the modified two-stream instability which converts about 50 percent of the ion energy into accelerated electrons along the loop as long as the plasma beta is less than 0.3. These electrons impact the chromosphere and boil off a part of it which rises up the loop. This density increase coupled with the temperature increase due to tearing causes the beta to increase beyond 0.3 and efficient electron acceleration ceases. This leads to the primarily thermal phase.
Characteristics of Norplant users.
McClanahan, P; Edwards, M R; Wise, R
2000-01-01
To determine whether a profile can be developed to indicate which clients are the best candidates for Norplant by describing the characteristics of clients who use this contraceptive for 5 years and those who have it removed early. A descriptive study of data collected from a convenience sample. SELLING: A state-supported university hospital's obstetric and gynecology outpatient clinic serving primarily indigent clients in the southern United States. Women (N = 256), primarily with low incomes, being seen for removal of Norplant contraceptive capsules. Of these, 166 women had completed the recommended 5 years. Characteristics of the clients who retained the contraceptive for the recommended 5 years and characteristics of clients who came for early removal. Clients who retained the contraceptive for 5 years differed from those who did not on only three characteristics: race, age, and parity. No significant differences were found in education or marital status. No clear profile of successful Norplant users emerged. Instead, thorough counseling of each individual is essential to the client's completion of 5 years with Norplant. Advantages and disadvantages must be explained and the client's tolerance of possible side effects must be assessed, thereby helping the client to make an informed choice.
Health and economic benefits of physical activity for patients with spinal cord injury.
Miller, Larry E; Herbert, William G
2016-01-01
Spinal cord injury (SCI) is a traumatic, life-disrupting event with an annual incidence of 17,000 cases in the US. SCI is characterized by progressive physical deconditioning due to limited mobility and lack of modalities to allow safe physical activity that may partially offset these deleterious physical changes. Approximately, 50% of patients with SCI report no leisure-time physical activity and 15% report leisure-time physical activity below the threshold where meaningful health benefits could be realized. Collectively, about 363,000 patients with SCI, or 65% of the entire spinal cord injured population in the US, engages in insufficient physical activity and represents a target population that could derive considerable health benefits from even modest physical activity levels. Currently, the annual direct costs related to SCI exceed US$45 billion in the US. Rehabilitation protocols and technologies aimed to improve functional mobility have potential to significantly reduce the risk of medical complications and cost associated with SCI. Patients who commence routine physical activity in the first post-injury year and experience typical motor function improvements would realize US$290,000 to US$435,000 in lifetime cost savings, primarily due to fewer hospitalizations and less reliance on assistive care. New assistive technologies that allow patients with SCI to safely engage in routine physical activity are desperately needed.
Hospital separations for cannabis- and methamphetamine-related psychotic episodes in Australia.
Degenhardt, Louisa; Roxburgh, Amanda; McKetin, Rebecca
2007-04-02
To examine trends in hospital separations related to "drug-induced" psychosis for cannabis and methamphetamine, in the context of patterns of cannabis and methamphetamine use in the Australian population. Analysis of prospectively collected data from the National Hospital Morbidity Database on hospital separations primarily attributed to drug-induced psychosis (July 1993 - June 2004), and specifically for cannabis and amphetamines (1999-2004). Calculation of Australian population-adjusted rates of drug-induced psychosis hospital separations using estimated resident population data from the Australian Bureau of Statistics (at 30 June each year) and data on cannabis and methamphetamine use from the 2004 National Drug Strategy Household Survey. Number of hospital separations due to drug-induced psychosis, and standardised (age-specific) rates per million population and per million users. There have been notable increases in hospital separations due to drug-induced psychosis, which appear to have been driven by amphetamine-related rather than cannabis-related episodes. The rate of hospital separations was higher for amphetamine users than for cannabis users in all age groups, and the rate increased among older amphetamine users. The risk of hospitalisation for a drug-induced psychotic episode associated with amphetamine use appears to be greater than that for cannabis use in all age groups.
Losacco, T; Cagiano, R; Luperto, P; Bera, I; Santacroce, L
2009-01-01
Foreign bodies of the upper aerodigestive tract are common problems encountered by the otolaryngologist and general surgeons. While the diagnosis seems straightforward, it is sometimes delayed until after serious complications have occurred. The treatment of choice is endoscopic retrieval under general anesthesia. The procedure should be preceded by the completion of appropriate studies (radiographic and other specifically indicated for the patient) planned and performed by the endoscopy team. Time invested in preparation and planning will usually yield a speedy recovery of the patient. Bran is a natural fiber that undergoes considerable expansion and thickening when hydrated. Due to this property, it has been used in "weight loss" tablets that in the stomach undergo expansion and are expected to cause early satiety. These tablets are usually marketed as over-the-counter (OTC) diet products by a number of pharmaceutical manufacturers. These supplements consisting primarily of dietary fibers, so common and inoffensive-seeming, rarely may have severe side effects, such a sudden esophageal obstruction. We report a case of a bran dietary product impacted in the cervical esophagus in a 45 year old woman, presenting as an emergency complaining of retrosternal discomfort and difficult to swallow or drink. The technique for removal of such object that is also reported.
Phytoremediation of landfill leachate.
Jones, D L; Williamson, K L; Owen, A G
2006-01-01
Leachate emissions from landfill sites are of concern, primarily due to their toxic impact when released unchecked into the environment, and the potential for landfill sites to generate leachate for many hundreds of years following closure. Consequently, economically and environmentally sustainable disposal options are a priority in waste management. One potential option is the use of soil-plant based remediation schemes. In many cases, using either trees (including short rotation coppice) or grassland, phytoremediation of leachate has been successful. However, there are a significant number of examples where phytoremediation has failed. Typically, this failure can be ascribed to excessive leachate application and poor management due to a fundamental lack of understanding of the plant-soil system. On balance, with careful management, phytoremediation can be viewed as a sustainable, cost effective and environmentally sound option which is capable of treating 250m(3)ha(-1)yr(-1). However, these schemes have a requirement for large land areas and must be capable of responding to changes in leachate quality and quantity, problems of scheme establishment and maintenance, continual environmental monitoring and seasonal patterns of plant growth. Although the fundamental underpinning science is well understood, further work is required to create long-term predictive remediation models, full environmental impact assessments, a complete life-cycle analysis and economic analyses for a wide range of landfill scenarios.
NASA Astrophysics Data System (ADS)
van Dam, T.; Wahr, J.; LavalléE, David
2007-03-01
We compare approximately 3 years of GPS height residuals (with respect to the International Terrestrial Reference Frame) with predictions of vertical surface displacements derived from the Gravity Recovery and Climate Experiment (GRACE) gravity fields for stations in Europe. An annual signal fit to the residual monthly heights, corrected for atmospheric pressure and barotropic ocean loading effects, should primarily represent surface displacements due to long-wavelength variations in water storage. A comparison of the annual height signal from GPS and GRACE over Europe indicates that at most sites, the annual signals do not agree in amplitude or phase. We find that unlike the annual signal predicted from GRACE, the annual signal in the GPS heights is not coherent over the region, displaying significant variability from site to site. Confidence in the GRACE data and the unlikely possibility of large-amplitude small-scale features in the load field not captured by the GRACE data leads us to conclude that some of the discrepancy between the GPS and GRACE observations is due to technique errors in the GPS data processing. This is evidenced by the fact that the disagreement between GPS and GRACE is largest at coastal sites, where mismodeling of the semidiurnal ocean tidal loading signal can result in spurious annual signals.
Robotic weld overlay coatings for erosion control
NASA Astrophysics Data System (ADS)
The erosion of materials by the impact of solid particles has received increasing attention during the past twenty years. Recently, research has been initiated with the event of advanced coal conversion processes in which erosion plays an important role. The resulting damage, termed Solid Particle Erosion (SPE), is of concern primarily because of the significantly increased operating costs which result in material failures. Reduced power plant efficiency due to solid particle erosion of boiler tubes and waterfalls has led to various methods to combat SPE. One method is to apply coatings to the components subjected to erosive environments. Protective weld overlay coatings are particularly advantageous in terms of coating quality. The weld overlay coatings are essentially immune to spallation due to a strong metallurgical bond with the substrate material. By using powder mixtures, multiple alloys can be mixed in order to achieve the best performance in an erosive environment. However, a review of the literature revealed a lack of information on weld overlay coating performance in erosive environments which makes the selection of weld overlay alloys a difficult task. The objective of this project is to determine the effects of weld overlay coating composition and microstructure on erosion resistance. These results will lead to a better understanding of erosion mitigation in CFB's.
Application of time-variable process noise in terrestrial reference frames determined from VLBI data
NASA Astrophysics Data System (ADS)
Soja, Benedikt; Gross, Richard S.; Abbondanza, Claudio; Chin, Toshio M.; Heflin, Michael B.; Parker, Jay W.; Wu, Xiaoping; Balidakis, Kyriakos; Nilsson, Tobias; Glaser, Susanne; Karbon, Maria; Heinkelmann, Robert; Schuh, Harald
2018-05-01
In recent years, Kalman filtering has emerged as a suitable technique to determine terrestrial reference frames (TRFs), a prime example being JTRF2014. The time series approach allows variations of station coordinates that are neither reduced by observational corrections nor considered in the functional model to be taken into account. These variations are primarily due to non-tidal geophysical loading effects that are not reduced according to the current IERS Conventions (2010). It is standard practice that the process noise models applied in Kalman filter TRF solutions are derived from time series of loading displacements and account for station dependent differences. So far, it has been assumed that the parameters of these process noise models are constant over time. However, due to the presence of seasonal and irregular variations, this assumption does not truly reflect reality. In this study, we derive a station coordinate process noise model allowing for such temporal variations. This process noise model and one that is a parameterized version of the former are applied in the computation of TRF solutions based on very long baseline interferometry data. In comparison with a solution based on a constant process noise model, we find that the station coordinates are affected at the millimeter level.
Patients with 47, XXX karyotype who experienced premature ovarian failure (POF): two case reports.
Sugawara, Nobuo; Maeda, Machiko; Manome, Tomomi; Nagai, Rie; Araki, Yasuhisa
2013-10-01
Pubertal onset and sexual development are usually normal in 47, XXX individuals; however, we report two cases of premature ovarian failure (POF) in infertile women with trisomy X. Chromosome analysis was conducted with G-banding and fluorescence in situ hybridization using X- and Y-bearing probe. Hormonal administration was primarily Kaufmann's treatment or long-term estradiol treatment, followed by withdrawal bleeding from estrogen and progesterone. Two patients with trisomy X, aged 31 (patient 1) and 27 years (patient 2), were diagnosed with POF due to hypergonadotropic hypogonadism. Their ovaries were small. Patient 1 had a FSH level of 44.6 mIU/ml and patient 2 had a FSH level of 74.6 mIU/ml. In patient 1, with Kaufmann's treatment, the FSH decreased to 13.5 mIU/ml; however, follicle growth did not occur following HMG stimulation. In patient 2, FSH did not decrease despite Kaufmann's treatment; therefore, she was given a GnRH agonist and her FSH level decreased to 7.1 mIU/ml. However, her ovaries never responded to HMG stimulation. We report on two patients with a 47, XXX karyotype who became infertile due to POF. We recommend that when a patient is diagnosed with trisomy X, the possibility of POF must be strongly considered.