Sample records for yorks ls23 7bq

  1. 7 CFR 929.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 929.23 Section 929.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... LONG ISLAND IN THE STATE OF NEW YORK Order Regulating Handling Administrative Body § 929.23 Selection...

  2. Molecular and functional characterization of CYP6BQ23, a cytochrome P450 conferring resistance to pyrethroids in European populations of pollen beetle, Meligethes aeneus.

    PubMed

    Zimmer, Christoph T; Bass, Chris; Williamson, Martin S; Kaussmann, Martin; Wölfel, Katharina; Gutbrod, Oliver; Nauen, Ralf

    2014-02-01

    The pollen beetle (Meligethes aeneus F.) is widespread throughout much of Europe where it is a major coleopteran pest of oilseed rape (Brassica napus). The reliance on synthetic insecticides for control, particularly the pyrethroid class, has led to the development of populations with high levels of resistance. Resistance to pyrethroids is now widespread throughout Europe and is thought to be mediated by enhanced detoxification by cytochrome P450ś and/or mutation of the pyrethroid target-site, the voltage-gated sodium channel. However, in the case of cytochrome P450 mediated detoxification, the specific enzyme(s) involved has (have) not yet been identified. In this study a degenerate PCR approach was used to identify ten partial P450 gene sequences from pollen beetle. Quantitative PCR was then used to examine the level of expression of these genes in a range of pollen beetle populations that showed differing levels of resistance to pyrethroids in bioassays. The study revealed a single P450 gene, CYP6BQ23, which is significantly and highly overexpressed (up to ∼900-fold) in adults and larvae of pyrethroid resistant strains compared to susceptible strains. CYP6BQ23 overexpression is significantly correlated with both the level of resistance and with the rate of deltamethrin metabolism in microsomal preparations of these populations. Functional recombinant expression of full length CYP6BQ23 along with cytochrome P450 reductase in an insect (Sf9) cell line showed that it is able to efficiently metabolise deltamethrin to 4-hydroxy deltamethrin. Furthermore we demonstrated by detection of 4-hydroxy tau-fluvalinate using ESI-TOF MS/MS that functionally expressed CYP6BQ23 also metabolizes tau-fluvalinate. A protein model was generated and subsequent docking simulations revealed the predicted substrate-binding mode of both deltamethrin and tau-fluvalinate to CYP6BQ23. Taken together these results strongly suggest that the overexpression of CYP6BQ23 is the primary

  3. The primary structure of aspartate aminotransferase from pig heart muscle. Partial sequences determined by digestion with thermolysin and elastase

    PubMed Central

    Bossa, Francesco; Barra, Donatella; Carloni, Massimo; Fasella, Paolo; Riva, Francesca; Doonan, Shawn; Doonan, Hilary J.; Hanford, Robin; Vernon, Charles A.; Walker, John M.

    1973-01-01

    Peptides produced by thermolytic digestion of aminoethylated aspartate aminotransferase and of the oxidized enzyme were isolated and their amino acid sequences determined. Digestion by elastase of the carboxymethylated enzyme gave peptides representing approximately 40% of the primary structure. Fragments from these digests overlapped with previously reported sequences of peptides obtained by peptic and tryptic digestion (Doonan et al., 1972), giving ten composite peptides containing 395 amino acid residues. The amino acid composition of these composite peptides agrees well with that of the intact enzyme. Confirmatory results for some of the present data have been deposited as Supplementary Publication 50018 at the National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973) 131, 5. PMID:4748834

  4. 46 CFR 7.30 - New York Harbor, NY.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false New York Harbor, NY. 7.30 Section 7.30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.30 New York Harbor, NY. A line drawn from East Rockaway Inlet Breakwater Light to Ambrose Light...

  5. An assessment of radon in groundwater in New York State

    USGS Publications Warehouse

    Shaw, Stephen B.; Eckhardt, David A.V.

    2012-01-01

    Abstract: A set of 317 samples collected from wells throughout New York State (excluding Long Island) from 2003 through 2008 was used to assess the distribution of radon gas in drinking water. Previous studies have documented high concentrations of radon in groundwater from granitic and metamorphic bedrock, but there have been only limited characterizations of radon in water from sedimentary rock and unconsolidated sand-and-gravel deposits in New York. Approximately 8% of the samples from bedrock wells exceed 89 Bq L-1 (eight times the proposed regulatory limit), but only 2% of samples from sand-and-gravel wells exceed 44 Bq L-1. Specific metamorphic and sedimentary rock formations in New York are associated with the high radon concentrations, indicating that specific areas of New York could be targeted with efforts to reduce the risk of exposure to radon in groundwater. Additionally, radon in groundwater from the sand-and-gravel aquifers was found to be directly correlated to radon in indoor air when assessed by county.

  6. Mars at Ls 53o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    23 May 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 53o during a previous Mars year. This month, Mars looks similar, as Ls 53o occurred in mid-May 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  7. Mars at Ls 211o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    23 May 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 211o during a previous Mars year. This month, Mars looks similar, as Ls 211o occurred in mid-May 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Autumn/Southern Spring

  8. Mars at Ls 269o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    23 August 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 269o during a previous Mars year. This month, Mars looks similar, as Ls 269o occurred in mid-August 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: last days of Northern Autumn/Southern Spring

  9. Flood of April 2-3, 2005, Esopus Creek Basin, New York

    USGS Publications Warehouse

    Suro, Thomas P.; Firda, Gary D.

    2007-01-01

    On April 2-3, 2005, heavy rain moved into southern New York and delivered rainfall amounts that ranged from about 2 in. to almost 6 in. within a 36-hour period. Significant flooding occurred on many small streams and tributaries in the area, and extensive flooding occurred on the Esopus and Roundout Creeks in Ulster and Greene Counties, New York. The flooding damaged many homes, caused millions of dollars worth of damage, and forced hundreds of residents to evacuate their homes. A total of 20 New York counties were declared Federal disaster areas. Disaster recovery assistance for those people affected stands at almost $35 million, according to the Federal Emergency Management Agency, as more than 3,400 New Yorkers registered for Federal aid. U.S. Geological Survey stream-gaging stations on the Esopus Creek above the Ashokan Reservoir at Allaben, N.Y., and below the Ashokan Reservoir at Mount Marion, N.Y., each recorded a new record maximum water-surface elevation and discharge for the respective periods of record as a result of this storm. The peak water-surface elevation and discharge recorded during the April 2-3, 2005, storm at the U.S. Geological Survey stream-gaging station on the Esopus Creek at Cold Brook, N.Y. were the third highest elevation and discharge since the station was put into operation in 1914. Most of the study sites along the Esopus Creek indicated water-surface elevations near the 50-year flood elevations, as documented in flood-insurance studies by the Federal Emergency Management Agency.

  10. ASTROPHYSICAL PARAMETERS OF LS 2883 AND IMPLICATIONS FOR THE PSR B1259-63 GAMMA-RAY BINARY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Negueruela, Ignacio; Lorenzo, Javier; Ribo, Marc

    2011-05-01

    Only a few binary systems with compact objects display TeV emission. The physical properties of the companion stars represent basic input for understanding the physical mechanisms behind the particle acceleration, emission, and absorption processes in these so-called gamma-ray binaries. Here we present high-resolution and high signal-to-noise optical spectra of LS 2883, the Be star forming a gamma-ray binary with the young non-accreting pulsar PSR B1259-63, showing it to rotate faster and be significantly earlier and more luminous than previously thought. Analysis of the interstellar lines suggests that the system is located at the same distance as (and thus is likelymore » a member of) Cen OB1. Taking the distance to the association, d = 2.3 kpc, and a color excess of E(B - V) = 0.85 for LS 2883 results in M{sub V} {approx} -4.4. Because of fast rotation, LS 2883 is oblate (R{sub eq} {approx_equal} 9.7 R{sub sun} and R{sub pole} {approx_equal} 8.1 R{sub sun}) and presents a temperature gradient (T{sub eq}{approx} 27,500 K, log g{sub eq} = 3.7; T{sub pole}{approx} 34,000 K, log g{sub pole} = 4.1). If the star did not rotate, it would have parameters corresponding to a late O-type star. We estimate its luminosity at log(L{sub *}/L{sub sun}) {approx_equal} 4.79 and its mass at M{sub *} {approx} 30 M{sub sun}. The mass function then implies an inclination of the binary system i{sub orb} {approx} 23{sup 0}, slightly smaller than previous estimates. We discuss the implications of these new astrophysical parameters of LS 2883 for the production of high-energy and very high-energy gamma rays in the PSR B1259-63/LS 2883 gamma-ray binary system. In particular, the stellar properties are very important for prediction of the line-like bulk Comptonization component from the unshocked ultrarelativistic pulsar wind.« less

  11. Results of the radiological survey at 23 Lily Street, Albany, New York

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Espegren, M.L.; Marley, J.L.; Carrier, R.F.

    1987-12-01

    A number of properties in the Albany/Colonie area have been identified as being potentially contaminated with uranium originating from the former National Lead Company's uranium forming plant in Colonie, New York. The property at 23 Lily Street in Albany, New York (AL174), was the subject of a radiological investigation initiated July 21, 1986. The residential property consists of a two-story frame house located on a rectangular lot. An asphalt driveway connects the house to the street. A diagram of the property showing the approximate boundaries and the 5-m grid network established for measurements outside the house is shown. The lotmore » included in the radiological survey was /approximately/20 m wide by 30 m deep. Front and side views of the property are shown. 13 refs., 5 figs., 5 tabs.« less

  12. Tokamak Equilibrium Reconstruction with MSE-LS Data in DIII-D

    NASA Astrophysics Data System (ADS)

    Lao, L.; Grierson, B.; Burrell, K. H.

    2016-10-01

    Equilibrium analysis of plasmas in DIII-D using EFIT was upgraded to include the internal magnetic field determined from spectroscopic measurements of motional-Stark-effect line-splitting (MSE-LS). MSE-LS provides measurements of the magnitude of the internal magnetic field, rather than the pitch angle as provided by MSE line-polarization (MSE-LP) used in most tokamaks to date. EFIT MSE-LS reconstruction algorithms and verifications are described. The capability of MSE-LS to provide significant constraints on the equilibrium analysis is evaluated. Reconstruction results with both synthetic and experimental MSE-LS data from 10 DIII-D discharges run over a range of conditions show that MSE-LS measurements can contribute to the equilibrium reconstruction of pressure and safety factor profiles. Adequate MSE-LS measurement accuracy and number of spatial locations are necessary. The 7 available experimental measurements provide useful additional constraints when used with other internal measurements. Using MSE-LS as the only internal measurement yields less current profile information. Work supported by the PPPL Subcontract S013769-F and US DOE under DE-FC02-04ER54698.

  13. Patient-related barriers to pain management: the Barriers Questionnaire II (BQ-II).

    PubMed

    Gunnarsdottir, Sigridur; Donovan, Heidi S; Serlin, Ronald C; Voge, Catherine; Ward, Sandra

    2002-10-01

    Patients' beliefs can act as barriers to optimal management of cancer pain. The Barriers Questionnaire (BQ) is a tool used to evaluate such barriers. Here, the BQ has been revised to reflect changes in pain management practices, resulting in the Barriers Questionnaire-II (BQ-II), a 27-item, self report instrument. This paper presents the results from two studies where the psychometric properties of the BQ-II were evaluated. In the first study, the responses of 27 nurses trained in pain management were compared to responses of a convenience sample of 12 patients with cancer. The results indicated that patients with cancer had higher mean scores on the BQ-II than did nurses trained in pain management. In the second study, a convenience sample of 172 patients with cancer responded to the BQ-II and a set of pain and quality of life (QOL) measures. A factor analysis supported four factors. Factor one, physiological effects, consists of 12 items addressing the beliefs that side effects of analgesics are inevitable and unmanageable, concerns about tolerance, and concerns about not being able to monitor changes in one's body when taking strong pain medications. Factor two, Fatalism, consists of three items addressing fatalistic beliefs about cancer pain and its management. Factor three, Communication, consists of six items addressing the concern that reports of pain distract the physician from treating the underlying disease, and the belief that 'good' patients do not complain of pain. The fourth and final factor, harmful effects, consists of six items addressing fear of becoming addicted to pain medication and the belief that pain medications harm the immune system. The BQ-II total had an internal consistency of 0.89, and alpha for the subscales ranged from 0.75 to 0.85. Mean (SD) scores on the total scale was 1.52 (0.73). BQ-II scores were related to measures of pain intensity and duration, mood, and QOL. Patients who used adequate analgesics for their levels of pain had

  14. Flood of April 2-3, 2005, Neversink River Basin, New York

    USGS Publications Warehouse

    Suro, Thomas P.; Firda, Gary D.

    2006-01-01

    Heavy rain on April 2-3, 2005 produced rainfall amounts of 3 inches to almost 6 inches within a 36-hour period throughout the Delaware River basin. Major flooding occurred in the East and West Branches of the Delaware River and their tributaries, the main stem of the Delaware River and the Neversink River, a major tributary to the Delaware River. The resultant flooding damaged hundreds of homes, caused millions of dollars in damage to infrastructure in Orange and Sullivan Counties, and forced more than 1,000 residents to evacuate their homes. A total of 20 New York counties were declared Federal disaster areas. Some of the most extensive flooding occurred along the Neversink and Delaware Rivers in Orange and Sullivan Counties, New York. Disaster recovery assistance from the April 2005 flooding in New York stood at almost $35 million in 2005, at which time more than 3,400 New Yorkers had registered for Federal aid. All U.S. Geological Survey stream-gaging stations on the Neversink River below the Neversink Reservoir recorded peak water-surface elevations higher than those recorded during the September 2004 flooding. Peak water-surface elevations at some study sites on the Neversink River exceeded the 500-year flood elevation as documented in flood-insurance studies by the Federal Emergency Management Agency. Flood peaks at some long-term U.S. Geological Survey stream-gaging stations were the highest ever recorded. Several U.S. Geological Survey stream-gaging stations on the Delaware River also recorded peak water-surface elevations that exceeded those recorded during the September 2004 flooding.

  15. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to the...

  16. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to the...

  17. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to the...

  18. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to the...

  19. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to the...

  20. Radon testing in schools in New York State: a 20-year summary.

    PubMed

    Kitto, Michael

    2014-11-01

    For nearly 20 years the Department of Health has conducted programs to assist in the measurement and reduction of indoor radon concentrations in 186 schools located primarily in Zone 1 areas of New York State. Although many schools had few or no rooms containing radon above 148 Bq/m(3), some rooms had >740 Bq/m(3) and remediation techniques were utilized to reduce exposure. Short-term radon measurements in the schools showed little correlation to basement and first-floor radon results from single-family homes in the towns. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Validation of GATE Monte Carlo simulations of the GE Advance/Discovery LS PET scanners.

    PubMed

    Schmidtlein, C Ross; Kirov, Assen S; Nehmeh, Sadek A; Erdi, Yusuf E; Humm, John L; Amols, Howard I; Bidaut, Luc M; Ganin, Alex; Stearns, Charles W; McDaniel, David L; Hamacher, Klaus A

    2006-01-01

    The recently developed GATE (GEANT4 application for tomographic emission) Monte Carlo package, designed to simulate positron emission tomography (PET) and single photon emission computed tomography (SPECT) scanners, provides the ability to model and account for the effects of photon noncollinearity, off-axis detector penetration, detector size and response, positron range, photon scatter, and patient motion on the resolution and quality of PET images. The objective of this study is to validate a model within GATE of the General Electric (GE) Advance/Discovery Light Speed (LS) PET scanner. Our three-dimensional PET simulation model of the scanner consists of 12 096 detectors grouped into blocks, which are grouped into modules as per the vendor's specifications. The GATE results are compared to experimental data obtained in accordance with the National Electrical Manufactures Association/Society of Nuclear Medicine (NEMA/SNM), NEMA NU 2-1994, and NEMA NU 2-2001 protocols. The respective phantoms are also accurately modeled thus allowing us to simulate the sensitivity, scatter fraction, count rate performance, and spatial resolution. In-house software was developed to produce and analyze sinograms from the simulated data. With our model of the GE Advance/Discovery LS PET scanner, the ratio of the sensitivities with sources radially offset 0 and 10 cm from the scanner's main axis are reproduced to within 1% of measurements. Similarly, the simulated scatter fraction for the NEMA NU 2-2001 phantom agrees to within less than 3% of measured values (the measured scatter fractions are 44.8% and 40.9 +/- 1.4% and the simulated scatter fraction is 43.5 +/- 0.3%). The simulated count rate curves were made to match the experimental curves by using deadtimes as fit parameters. This resulted in deadtime values of 625 and 332 ns at the Block and Coincidence levels, respectively. The experimental peak true count rate of 139.0 kcps and the peak activity concentration of 21.5 kBq

  2. 23 CFR 172.7 - Audits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Audits. 172.7 Section 172.7 Highways FEDERAL HIGHWAY... 23 U.S.C. 112 and this part provided that the consultant is given notice of each use and transfer... subrecpient's acceptance of a consultant's overhead rates pursuant to 23 U.S.C. 112 and this part without the...

  3. 23 CFR 172.7 - Audits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Audits. 172.7 Section 172.7 Highways FEDERAL HIGHWAY... 23 U.S.C. 112 and this part provided that the consultant is given notice of each use and transfer... subrecpient's acceptance of a consultant's overhead rates pursuant to 23 U.S.C. 112 and this part without the...

  4. 23 CFR 172.7 - Audits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Audits. 172.7 Section 172.7 Highways FEDERAL HIGHWAY... 23 U.S.C. 112 and this part provided that the consultant is given notice of each use and transfer... subrecpient's acceptance of a consultant's overhead rates pursuant to 23 U.S.C. 112 and this part without the...

  5. 49 CFR 23.7 - Program reviews.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Program reviews. 23.7 Section 23.7 Transportation... CONCESSIONS General § 23.7 Program reviews. In 2010, and thereafter at the discretion of the Secretary, the Department will initiate a review of the ACDBE program to determine what, if any, modifications should be...

  6. 7 CFR 774.23 - Loan servicing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Loan servicing. 774.23 Section 774.23 Agriculture... SPECIAL PROGRAMS EMERGENCY LOAN FOR SEED PRODUCERS PROGRAM § 774.23 Loan servicing. Loans will be serviced as a Non-program loan in accordance with 7 CFR part 766. If the loan is not repaid as agreed and...

  7. 7 CFR 1230.23 - Research.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Research. 1230.23 Section 1230.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PORK PROMOTION, RESEARCH, AND CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.23...

  8. 7 CFR 1230.23 - Research.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Research. 1230.23 Section 1230.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PORK PROMOTION, RESEARCH, AND CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.23...

  9. 7 CFR 1230.23 - Research.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Research. 1230.23 Section 1230.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PORK PROMOTION, RESEARCH, AND CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.23...

  10. 7 CFR 1230.23 - Research.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Research. 1230.23 Section 1230.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PORK PROMOTION, RESEARCH, AND CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.23...

  11. 7 CFR 1230.23 - Research.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Research. 1230.23 Section 1230.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PORK PROMOTION, RESEARCH, AND CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.23...

  12. 7 CFR 1221.23 - Promotion.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Promotion. 1221.23 Section 1221.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SORGHUM PROMOTION, RESEARCH, AND INFORMATION ORDER Sorghum Promotion, Research, and Information Order Definitions § 1221.23 Promotion...

  13. 7 CFR 925.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 925.23 Section 925.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... SOUTHEASTERN CALIFORNIA Administrative Body § 925.23 Selection. The Secretary shall select members and...

  14. 7 CFR 923.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 923.23 Section 923.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... COUNTIES IN WASHINGTON Order Regulating Handling Administrative Body § 923.23 Selection. From the...

  15. 7 CFR 922.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 922.23 Section 922.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... IN WASHINGTON Order Regulating Handling Administrative Body § 922.23 Selection. From the nominations...

  16. 7 CFR 1219.23 - Research.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Research. 1219.23 Section 1219.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.23 Research...

  17. 7 CFR 1219.23 - Research.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Research. 1219.23 Section 1219.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.23 Research...

  18. 7 CFR 1219.23 - Research.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Research. 1219.23 Section 1219.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.23 Research...

  19. 7 CFR 1219.23 - Research.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Research. 1219.23 Section 1219.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.23 Research...

  20. 7 CFR 1219.23 - Research.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Research. 1219.23 Section 1219.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.23 Research...

  1. 7 CFR 1216.23 - Promotion.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Promotion. 1216.23 Section 1216.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.23 Promotion. Promotion...

  2. 7 CFR 3015.23 - Microfilm.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Microfilm. 3015.23 Section 3015.23 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Record Retention and Access Requirements § 3015.23...

  3. 7 CFR 905.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 905.23 Section 905.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... TANGELOS GROWN IN FLORIDA Order Regulating Handling Administrative Bodies § 905.23 Selection. (a) From the...

  4. 7 CFR 1781.23 - Servicing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Servicing. 1781.23 Section 1781.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) RESOURCE CONSERVATION AND DEVELOPMENT (RCD) LOANS AND WATERSHED (WS) LOANS AND ADVANCES § 1781.23...

  5. 7 CFR 1781.23 - Servicing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Servicing. 1781.23 Section 1781.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) RESOURCE CONSERVATION AND DEVELOPMENT (RCD) LOANS AND WATERSHED (WS) LOANS AND ADVANCES § 1781.23...

  6. 7 CFR 1781.23 - Servicing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Servicing. 1781.23 Section 1781.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) RESOURCE CONSERVATION AND DEVELOPMENT (RCD) LOANS AND WATERSHED (WS) LOANS AND ADVANCES § 1781.23...

  7. 7 CFR 1781.23 - Servicing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Servicing. 1781.23 Section 1781.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) RESOURCE CONSERVATION AND DEVELOPMENT (RCD) LOANS AND WATERSHED (WS) LOANS AND ADVANCES § 1781.23...

  8. 7 CFR 1781.23 - Servicing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Servicing. 1781.23 Section 1781.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) RESOURCE CONSERVATION AND DEVELOPMENT (RCD) LOANS AND WATERSHED (WS) LOANS AND ADVANCES § 1781.23...

  9. 7 CFR 915.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 915.23 Section 915.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Administrative Body § 915.23 Selection. From the nominations made pursuant to § 915.22...

  10. 7 CFR 924.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 924.23 Section 924.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements....23 Selection. From the nominations made pursuant to § 924.22, or from other qualified persons, the...

  11. 7 CFR 916.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 916.23 Section 916.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Administrative Body § 916.23 Selection. From the nominations made pursuant to § 916.22...

  12. 7 CFR 920.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 920.23 Section 920.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Administrative Body § 920.23 Selection. From the nominations made pursuant to § 920.22, or from other qualified...

  13. 7 CFR 23.10 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Administration. 23.10 Section 23.10 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.10 Administration. (a) The Regional Programs will be administered through four Regional Rural Development Centers...

  14. 7 CFR 23.10 - Administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Administration. 23.10 Section 23.10 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.10 Administration. (a) The Regional Programs will be administered through four Regional Rural Development Centers...

  15. 7 CFR 1425.23 - Reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Reports. 1425.23 Section 1425.23 Agriculture... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COOPERATIVE MARKETING ASSOCIATIONS § 1425.23 Reports. (a) CMA's shall annually provide CCC a report of all commodity deliveries involved in loans and LDP's by...

  16. 7 CFR 1425.23 - Reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Reports. 1425.23 Section 1425.23 Agriculture... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COOPERATIVE MARKETING ASSOCIATIONS § 1425.23 Reports. (a) CMA's shall annually provide CCC a report of all commodity deliveries involved in loans and LDP's by...

  17. 7 CFR 23.10 - Administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Administration. 23.10 Section 23.10 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.10 Administration. (a) The Regional Programs will be administered through four Regional Rural Development Centers...

  18. [Quality of advanced practice nurse counseling in home care settings (APN-BQ): psychometric testing of the instrument].

    PubMed

    Petry, Heidi; Suter-Riederer, Susanne; Kerker-Specker, Carmen; Imhof, Lorenz

    2014-12-01

    Patient centred and individually-tailored counselling of older people with a chronic condition who live at home is a useful intervention to support their independence. The paper presents the development and psychometric testing of the APN-BQ Instrument, to measure patient-centeredness. To measure the quality of an in-home counselling intervention, a 23-item questionnaire was developed and tested with 206 people 80 years and older. Principal component analysis with Varimax Rotation was conducted (n = 206). Analysis revealed a four factor (fs = 0.91) model scoring in 19 items. All factors loaded > 0.45. Cronbach's alpha was 0.86. The utility and acceptance of the instrument was confirmed by the high response rate (100 %) and the fact that participants answered 98.8 % of all questions. The APN-BQ has shown to be a reliable Instrument with good content and construct validity. It is a tool for APNs to measure structure, process, and outcome quality of a patient-centred and individually-tailored counselling program, including the degree of patient participation, and patient empowerment.

  19. 7 CFR 989.23 - File.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false File. 989.23 Section 989.23 Agriculture Regulations of... CALIFORNIA Order Regulating Handling Definitions § 989.23 File. File means transmit or deliver to the... time: (a) Of actual receipt by the Secretary or committee in the event of personal delivery; (b) Of...

  20. 7 CFR 989.23 - File.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false File. 989.23 Section 989.23 Agriculture Regulations of... CALIFORNIA Order Regulating Handling Definitions § 989.23 File. File means transmit or deliver to the... time: (a) Of actual receipt by the Secretary or committee in the event of personal delivery; (b) Of...

  1. Radar Images of Asteroid 2017 BQ6

    NASA Image and Video Library

    2017-02-10

    This composite of 11 images of asteroid 2017 BQ6 was generated with radar data collected using NASA's Goldstone Solar System Radar in California's Mojave Desert on Feb. 5, 2017, between 5:24 and 5:52 p.m. PST (8:24 to 8:52 p.m. EST / 1:24 to 1:52 UTC). The images have resolutions as fine as 12 feet (3.75 meters) per pixel. http://photojournal.jpl.nasa.gov/catalog/PIA21453

  2. 36 CFR 7.23 - Badlands National Park.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Badlands National Park. 7.23 Section 7.23 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.23 Badlands National Park. (a) Commercial vehicles. (1...

  3. 36 CFR 7.23 - Badlands National Park.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Badlands National Park. 7.23 Section 7.23 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.23 Badlands National Park. (a) Commercial vehicles. (1...

  4. 36 CFR 7.23 - Badlands National Park.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Badlands National Park. 7.23 Section 7.23 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.23 Badlands National Park. (a) Commercial vehicles. (1...

  5. 36 CFR 7.23 - Badlands National Park.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Badlands National Park. 7.23 Section 7.23 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.23 Badlands National Park. (a) Commercial vehicles. (1...

  6. 36 CFR 7.23 - Badlands National Park.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Badlands National Park. 7.23 Section 7.23 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.23 Badlands National Park. (a) Commercial vehicles. (1...

  7. United States and New York State History, Grade 7. A Multicultural Perspective. Volume I.

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY.

    This resource guide, designed for use by New York City teachers, provides a wide range of suggested approaches and materials from which teachers can select as they teach the grade 7 and grade 8 course "United States and New York State History." The resource guide strives to include the histories, perspectives, and contributions of all…

  8. Mars at Ls 137o

    NASA Technical Reports Server (NTRS)

    2006-01-01

    13 November 2006 These images capture what Mars typically looks like in mid-afternoon at Ls 137o. In other words, with the exception of occasional differences in weather and polar frost patterns, this is what the red planet looks like this month (November 2006).

    Six views are shown, including the two polar regions. These are composites of 24-26 Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global mapping images acquired at red and blue wavelengths. The 'hole' over the south pole is an area where no images were obtained, because this polar region is enveloped in wintertime darkness.

    Presently, it is summer in the northern hemisphere and winter in the southern hemisphere. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn. Northern summer/southern winter begins at Ls 90o, northern autumn/southern spring start at Ls 180o, and northern winter/southern summer begin at Ls 270o.

    Ls 137o occurs in the middle of this month (November 2006). The pictures show how Mars appeared to the MOC wide angle cameras at a previous Ls 137o in March 2001. The six views are centered on the Tharsis region (upper left), Acidalia and Mare Eyrthraeum (upper right), Syrtis Major and Hellas (middle left), Elysium and Mare Cimmeria (middle right), the north pole (lower left), and the south pole (lower right).

  9. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors.

    PubMed

    Inserra, Marco C; Kompella, Shiva N; Vetter, Irina; Brust, Andreas; Daly, Norelle L; Cuny, Hartmut; Craik, David J; Alewood, Paul F; Adams, David J; Lewis, Richard J

    2013-09-15

    A new α-conotoxin LsIA was isolated from the crude venom of Conus limpusi using assay-guided RP-HPLC fractionation. Synthetic LsIA was a potent antagonist of α3β2, α3α5β2 and α7 nAChRs, with half-maximal inhibitory concentrations of 10, 31 and 10 nM, respectively. The structure of LsIA determined by NMR spectroscopy comprised a characteristic disulfide bond-stabilized α-helical structure and disordered N-terminal region. Potency reductions of up to 9-fold were observed for N-terminally truncated analogues of LsIA at α7 and α3β2 nAChRs, whereas C-terminal carboxylation enhanced potency 3-fold at α3β2 nAChRs but reduced potency 3-fold at α7 nAChRs. This study gives further insight into α-conotoxin pharmacology and the molecular basis of nAChR selectivity, highlighting the influence of N-terminal residues and C-terminal amidation on conotoxin pharmacology. Copyright © 2013. Published by Elsevier Inc.

  10. 7 CFR 920.23 - Selection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Selection. 920.23 Section 920.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  11. 7 CFR 920.23 - Selection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Selection. 920.23 Section 920.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  12. 7 CFR 920.23 - Selection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Selection. 920.23 Section 920.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  13. 7 CFR 920.23 - Selection.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Selection. 920.23 Section 920.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  14. 7 CFR 1217.23 - Research.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Research. 1217.23 Section 1217.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOFTWOOD LUMBER RESEARCH, PROMOTION, CONSUMER EDUCATION AND INDUSTRY INFORMATION ORDER Softwood Lumber Research, Promotion, Consumer Education...

  15. 7 CFR 1217.23 - Research.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Research. 1217.23 Section 1217.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOFTWOOD LUMBER RESEARCH, PROMOTION, CONSUMER EDUCATION AND INDUSTRY INFORMATION ORDER Softwood Lumber Research, Promotion, Consumer Education...

  16. 7 CFR 1217.23 - Research.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Research. 1217.23 Section 1217.23 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOFTWOOD LUMBER RESEARCH, PROMOTION, CONSUMER EDUCATION AND INDUSTRY INFORMATION ORDER Softwood Lumber Research, Promotion, Consumer Education...

  17. 7 CFR 989.23 - File.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false File. 989.23 Section 989.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE RAISINS PRODUCED FROM GRAPES GROWN IN...

  18. 7 CFR 989.23 - File.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false File. 989.23 Section 989.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE RAISINS PRODUCED FROM GRAPES GROWN IN...

  19. 7 CFR 989.23 - File.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false File. 989.23 Section 989.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE RAISINS PRODUCED FROM GRAPES GROWN IN...

  20. 7 CFR 322.23 - Documentation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Documentation. 322.23 Section 322.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE BEES, BEEKEEPING BYPRODUCTS, AND BEEKEEPING EQUIPMENT Transit of Restricted...

  1. 7 CFR 322.23 - Documentation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 5 2013-01-01 2013-01-01 false Documentation. 322.23 Section 322.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE BEES, BEEKEEPING BYPRODUCTS, AND BEEKEEPING EQUIPMENT Transit of Restricted...

  2. 7 CFR 322.23 - Documentation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 5 2011-01-01 2011-01-01 false Documentation. 322.23 Section 322.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE BEES, BEEKEEPING BYPRODUCTS, AND BEEKEEPING EQUIPMENT Transit of Restricted...

  3. 7 CFR 322.23 - Documentation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Documentation. 322.23 Section 322.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE BEES, BEEKEEPING BYPRODUCTS, AND BEEKEEPING EQUIPMENT Transit of Restricted...

  4. 7 CFR 322.23 - Documentation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 5 2014-01-01 2014-01-01 false Documentation. 322.23 Section 322.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE BEES, BEEKEEPING BYPRODUCTS, AND BEEKEEPING EQUIPMENT Transit of Restricted...

  5. 7 CFR 955.23 - Selection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Selection. 955.23 Section 955.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE VIDALIA ONIONS GROWN IN GEORGIA...

  6. 7 CFR 955.23 - Selection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Selection. 955.23 Section 955.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE VIDALIA ONIONS GROWN IN GEORGIA...

  7. 7 CFR 955.23 - Selection.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Selection. 955.23 Section 955.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE VIDALIA ONIONS GROWN IN GEORGIA...

  8. 7 CFR 955.23 - Selection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Selection. 955.23 Section 955.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE VIDALIA ONIONS GROWN IN GEORGIA...

  9. 7 CFR 955.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 955.23 Section 955.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE VIDALIA ONIONS GROWN IN GEORGIA...

  10. 7 CFR 915.23 - Selection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Selection. 915.23 Section 915.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE AVOCADOS GROWN IN SOUTH FLORIDA Order...

  11. 7 CFR 915.23 - Selection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Selection. 915.23 Section 915.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE AVOCADOS GROWN IN SOUTH FLORIDA Order...

  12. 7 CFR 925.23 - Selection.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Selection. 925.23 Section 925.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE GRAPES GROWN IN A DESIGNATED AREA OF...

  13. 7 CFR 925.23 - Selection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Selection. 925.23 Section 925.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE GRAPES GROWN IN A DESIGNATED AREA OF...

  14. 7 CFR 925.23 - Selection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Selection. 925.23 Section 925.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE GRAPES GROWN IN A DESIGNATED AREA OF...

  15. 7 CFR 925.23 - Selection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Selection. 925.23 Section 925.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE GRAPES GROWN IN A DESIGNATED AREA OF...

  16. 7 CFR 956.23 - Selection.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Selection. 956.23 Section 956.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE SWEET ONIONS GROWN IN THE WALLA WALLA...

  17. 7 CFR 956.23 - Selection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Selection. 956.23 Section 956.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE SWEET ONIONS GROWN IN THE WALLA WALLA...

  18. 7 CFR 956.23 - Selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Selection. 956.23 Section 956.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE SWEET ONIONS GROWN IN THE WALLA WALLA...

  19. 7 CFR 956.23 - Selection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Selection. 956.23 Section 956.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE SWEET ONIONS GROWN IN THE WALLA WALLA...

  20. 7 CFR 956.23 - Selection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Selection. 956.23 Section 956.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE SWEET ONIONS GROWN IN THE WALLA WALLA...

  1. A two-step spin crossover mononuclear iron(II) complex with a [HS-LS-LS] intermediate phase.

    PubMed

    Bonnet, Sylvestre; Siegler, Maxime A; Costa, José Sánchez; Molnár, Gábor; Bousseksou, Azzedine; Spek, Anthony L; Gamez, Patrick; Reedijk, Jan

    2008-11-21

    The two-step spin crossover of a new mononuclear iron(ii) complex is studied by magnetic, crystallographic and calorimetric methods revealing two successive first-order phase transitions and an ordered intermediate phase built by the repetition of the unprecedented [HS-LS-LS] motif.

  2. 7 CFR 1206.23 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false United States. 1206.23 Section 1206.23 Agriculture... INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.23 United States. United... Rico, and the territories and possessions of the United States. ...

  3. 7 CFR 1206.23 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false United States. 1206.23 Section 1206.23 Agriculture... INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.23 United States. United... Rico, and the territories and possessions of the United States. ...

  4. 7 CFR 1206.23 - United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false United States. 1206.23 Section 1206.23 Agriculture... INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.23 United States. United... Rico, and the territories and possessions of the United States. ...

  5. 7 CFR 1206.23 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false United States. 1206.23 Section 1206.23 Agriculture... INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.23 United States. United... Rico, and the territories and possessions of the United States. ...

  6. 23 CFR 940.7 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Applicability. 940.7 Section 940.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INTELLIGENT TRANSPORTATION SYSTEMS INTELLIGENT TRANSPORTATION SYSTEM ARCHITECTURE AND STANDARDS § 940.7 Applicability. (a) All ITS projects that are funded in...

  7. Serotoninergic neuronal systems and ethanol sensitivity in long-sleep (LS) and short-sleep (SS) mice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    French, T.A.; Weiner, N.

    LS and SS mice selectively bred for differences in CNS sensitivity to ethanol (EtOH) exhibit markedly different sleep times (LS = 120 min; SS = 13 min) and differ considerably in hypothermic response following EtOH< 4 g/kg i.p. Basal levels of serotonin (5HT), 5-hydroxyindole acetic acid and 5HT turnover (defined as 5-hydroxy-tryptophan accumulation after inhibition of aromatic L-amino acid decarboxylase) in 6 brain regions (hypthalamus (HYP), dorsal raphe (DR), pontine-medullary raphe (PMR), striatum (STR), hippocampus (HIP) and cortex (CTX)) differ minimally between the two lines. 5 HT turnover in STR, HIP, CTX and PMR of either LS or SS micemore » or in HYP or DR of SS mice was not altered at either 20 or 120 min after EtOH, 4 g/kg. However, in LS mice, 5HT turnover was decreased 23% in HYP at 20 min and 30-34% in HYP and DR at 120 min. LS mice become 1.2 and 2.2/sup 0/ more hypothermic than SS mice at 20 and 120 min after EtOH, 4 g/kg. When approximately equi-effective hypothermic doses of EtOH were administered to LS (3.5 g/kg) and SS (5.0 g/kg) mice, differences in 5HT turnover were still apparent. Pentobarbital administration (65 mg/kg) both decreased brain 5HT turnover 30-60% and produced comparable degrees of hypothermia in LS and SS mice. These data suggest that the apparent increase in sensitivity to inhibition by EtOH of 5HT neurons of HYP and DR of LS mice may contribute to the greater degree of hypothermia induced in this line.« less

  8. In vitro and in vivo activity of LS 4477 and LS 4559, novel analogues of the tubulin binder estramustine.

    PubMed

    Nicholson, K M; Phillips, R M; Shnyder, S D; Bibby, M C

    2002-01-01

    LS 4477 and LS 4559, two of a series of N-acyl-aminoalkyl phenyl ethers, are rationally designed compounds based on the tubulin binder estramustine. This study investigated their mechanism of action and compared their effectiveness in relation to estramustine in vitro against a panel of human and murine cell lines and in vivo against two murine colon tumour models (MAC). At biologically relevant concentrations, LS 4477 and LS 4559 caused a 59.9 and 56% reduction in tubulin assembly, respectively, compared with a 28.4% reduction in tubulin assembly by estramustine. The analogues were approximately 100 times more potent in chemosensitivity tests in vitro than the parent compound. Both analogues were orally active against the MAC 15A murine tumour model, to a greater extent than estramustine, producing significant growth delays (P<0.01). Significant activity was also shown against the slower growing MAC 26 tumour for LS 4577 (the soluble pro-drug of LS 4559). The results presented in this study suggest these compounds warrant further development with a view to assessing their clinical activity.

  9. 23 CFR 751.7 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Definitions. 751.7 Section 751.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT JUNKYARD CONTROL AND ACQUISITION § 751.7 Definitions. For purposes of this part, the following definitions shall apply: (a...

  10. A morphological study of the pacemaker cells of the aganglionic intestine in Hirschsprung's disease utilizing ls/ls model mice.

    PubMed

    Taniguchi, Kan; Matsuura, Kimio; Matsuoka, Takanori; Nakatani, Hajime; Nakano, Takumi; Furuya, Yasuo; Sugimoto, Takeki; Kobayashi, Michiya; Araki, Keijiro

    2005-06-01

    Hirschsprung's disease is a congenital aganglionic neural disorder of the segmental distal intestine characterized by unsettled pathogenesis. The relationship between Hirschsprung's disease and pacemaker cells (PMC), which almost corresponds to that of the interstitial cells of Cajal (ICC), was morphologically observed at the level of the intermuscular layer corresponding to Auerbach's plexus using ls/ls mice. These mice are an ideal model because of their large intestinal aganglionosis and gene abnormalities, which are similar to the human form of the disease. Immunostaining using anti-c-kit receptor antibody (ACK2), a marker of PMC, applied to whole-mount muscle-layer specimens, revealed the presence of c-kit immunopositive multipolar cells with many cytoplasmic processes in normal mice. For ls/ls mice, however, there were significantly fewer processes. The average number of processes per positive cell of 2.5 for the aganglionic large intestine was fewer than 3.5 for the large and small intestine of normal mice, indicating the inability to form connections between nerves and PMC in the aganglionic intestine. For normal mice with an Auerbach's plexus, the process attachment of ICC to the Auerbach's plexus was observed by scanning electron microscopy. However, for ls/ls mice no attachment to the intermuscular nerve without Auerbach's plexus was found, although transmission electron microscopy showed no difference in the cell structure and organelles of the c-kit immunopositive cells between the normal and ls/ls mice. These findings suggest that in the aganglionic intestine of Hirschsprung's disease, aplasia of enteric ganglia induces secondary disturbances during the normal development of intestinal PMC.

  11. 7 CFR 91.23 - Analytical methods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Analytical methods. 91.23 Section 91.23 Agriculture... SERVICES AND GENERAL INFORMATION Method Manuals § 91.23 Analytical methods. Most analyses are performed according to approved procedures described in manuals of standardized methodology. These standard methods...

  12. 7 CFR 91.23 - Analytical methods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Analytical methods. 91.23 Section 91.23 Agriculture... SERVICES AND GENERAL INFORMATION Method Manuals § 91.23 Analytical methods. Most analyses are performed according to approved procedures described in manuals of standardized methodology. These standard methods...

  13. 7 CFR 91.23 - Analytical methods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Analytical methods. 91.23 Section 91.23 Agriculture... SERVICES AND GENERAL INFORMATION Method Manuals § 91.23 Analytical methods. Most analyses are performed according to approved procedures described in manuals of standardized methodology. These standard methods...

  14. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures ...

  15. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures ...

  16. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures ...

  17. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures ...

  18. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures ... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1205.23 Section 1205.23 Agriculture...

  19. 27 CFR 7.23 - Brand names.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Brand names. 7.23 Section... Beverages § 7.23 Brand names. (a) General. The product shall bear a brand name, except that if not sold under a brand name, then the name of the person required to appear on the brand label shall be deemed a...

  20. 7 CFR 1206.23 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.23 United States. United States or U.S. means collectively the 50 states, the District of Columbia, the Commonwealth of Puerto... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1206.23 Section 1206.23 Agriculture...

  1. 7 CFR 23.2 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Administration. 23.2 Section 23.2 Agriculture Office... Administration. (a) Title V will be administered by the Administrators of the Extension Service and the... Act of 1914 and the Hatch Act (as amended), August 11, 1955, the administration of the programs shall...

  2. 7 CFR 23.2 - Administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Administration. 23.2 Section 23.2 Agriculture Office... Administration. (a) Title V will be administered by the Administrators of the Extension Service and the... Act of 1914 and the Hatch Act (as amended), August 11, 1955, the administration of the programs shall...

  3. 23 CFR 172.7 - Audits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Audits. 172.7 Section 172.7 Highways FEDERAL HIGHWAY... SERVICE CONTRACTS § 172.7 Audits. (a) Performance of audits. When State procedures call for audits of contracts or subcontracts for engineering design services, the audit shall be performed to test compliance...

  4. 7 CFR 283.23 - Procedural matters.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

  5. 7 CFR 283.23 - Procedural matters.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

  6. 7 CFR 283.23 - Procedural matters.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

  7. 7 CFR 283.23 - Procedural matters.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

  8. 7 CFR 283.23 - Procedural matters.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

  9. 7 CFR 550.23 - Program income.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Program income. 550.23 Section 550.23 Agriculture... Financial Management § 550.23 Program income. (a) REE Agencies shall apply the standards set forth in this section in requiring Cooperator organizations to account for program income related to projects financed...

  10. 7 CFR 319.8-23 - Treatment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Treatment. 319.8-23 Section 319.8-23 Agriculture....8-23 Treatment. (a)(1) Vacuum fumigation as required in this subpart shall consist of fumigation, in... the substitution of processing, utilization, or other form of treatment for vacuum fumigation when in...

  11. 7 CFR 15a.23 - Recruitment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Recruitment. 15a.23 Section 15a.23 Agriculture Office... FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 15a.23 Recruitment. (a) Nondiscriminatory recruitment. A recipient to which this subpart applies shall...

  12. Mars at Ls 145o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 145 during a previous Mars year. This month, Mars looked similar, as Ls 145 occurred in mid-January 2005.

    This picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year were posted for MOC Picture of the Day.

    Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360 around the Sun in 1 Mars year. The year begins at Ls 0 -- the start of northern spring and southern summer. In January 2005, it is northern summer and southern winter. The seasons on Mars occur according to Ls, described in the following table:

    Ls Season 0 - 90 northern spring, southern autumn 90 - 180 northern summer, southern winter 180 - 270 northern autumn, southern spring 270 - 360 northern winter, southern summer

  13. Mars at Ls 288°: Syrtis Major

    NASA Image and Video Library

    2005-09-21

    This picture, released 21 September 2005, is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 288° during a previous Mars year. This month, Mars looks similar, as Ls 288° occurred in mid-September 2005. The picture shows the Syrtis Major face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, are a measure of the time of year on Mars. Mars travels 360° around the Sun in 1 Mars year. The year begins at Ls 0°, the start of northern spring and southern autumn.

  14. 23 CFR 658.7 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Applicability. 658.7 Section 658.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS TRUCK SIZE AND... access thereto. However, nothing in this regulation shall be construed to prevent any State from applying...

  15. 23 CFR 658.7 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Applicability. 658.7 Section 658.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS TRUCK SIZE AND... access thereto. However, nothing in this regulation shall be construed to prevent any State from applying...

  16. 23 CFR 658.7 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Applicability. 658.7 Section 658.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS TRUCK SIZE AND... access thereto. However, nothing in this regulation shall be construed to prevent any State from applying...

  17. 23 CFR 658.7 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Applicability. 658.7 Section 658.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS TRUCK SIZE AND... access thereto. However, nothing in this regulation shall be construed to prevent any State from applying...

  18. 23 CFR 658.7 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Applicability. 658.7 Section 658.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS TRUCK SIZE AND... access thereto. However, nothing in this regulation shall be construed to prevent any State from applying...

  19. 23 CFR 657.7 - Objective.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of an enforcement process which identifies vehicles of excessive size and weight and provides a... 23 Highways 1 2010-04-01 2010-04-01 false Objective. 657.7 Section 657.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS CERTIFICATION OF SIZE AND WEIGHT...

  20. Amino acid sequence of the smaller basic protein from rat brain myelin

    PubMed Central

    Dunkley, Peter R.; Carnegie, Patrick R.

    1974-01-01

    1. The complete amino acid sequence of the smaller basic protein from rat brain myelin was determined. This protein differs from myelin basic proteins of other species in having a deletion of a polypeptide of 40 amino acid residues from the centre of the molecule. 2. A detailed comparison is made of the constant and variable regions in a group of myelin basic proteins from six species. 3. An arginine residue in the rat protein was found to be partially methylated. The ratio of methylated to unmethylated arginine at this position differed from that found for the human basic protein. 4. Three tryptic peptides were isolated in more than one form. The differences between the two forms of each peptide are discussed in relation to the electrophoretic heterogeneity of myelin basic proteins, which is known to occur at alkaline pH values. 5. Detailed evidence for the amino acid sequence of the protein has been deposited as Supplementary Publication SUP 50029 at the British Library (Lending Division) (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms given in Biochem. J. (1973) 131, 5. PMID:4141893

  1. Mars at Ls 145o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    11 January 2004 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 145o during a previous Mars year. This month, Mars looks similar, as Ls 145o occurs in mid-January 2005.

    This picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day.

    Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o--the start of northern spring and southern summer. In January 2005, it is northern summer and southern winter. The seasons on Mars occur according to Ls, described in thefollowing table:

    Ls Season 0 - 90 northern spring, southern autumn 90 - 180 northern summer, southern winter 180 - 270 northern autumn, southern spring 270 - 360 northern winter, southern summer

  2. LifeSkills for Men (LS4M): Pilot Evaluation of a Gender-Affirmative HIV and STI Prevention Intervention for Young Adult Transgender Men Who Have Sex with Men.

    PubMed

    Reisner, Sari L; Hughto, Jaclyn M White; Pardee, Dana J; Kuhns, Lisa; Garofalo, Rob; Mimiaga, Matthew J

    2016-02-01

    Young adult transgender men who have sex with men (TMSM) engage in sexual behaviors that place them at risk of sexually transmitted infections (STIs) including HIV. To date, no HIV and STI prevention interventions have been developed specifically for young adult TMSM. To address this gap, the current study aimed to (1) adapt a small group-based behavioral HIV prevention intervention designed for young transgender women ("LifeSkills") to address the unique HIV and STI prevention needs of young TMSM ages 18-29 years and (2) conduct a pilot evaluation of the intervention ("LifeSkills for Men"; LS4M). LS4M was carried out in an iterative approach with community input along the way, which allowed for refinement of the intervention manual and enhanced participant acceptability. A LS4M Task Force was convened to guide intervention development/adaptation and study implementation. Initially, focus groups were conducted to examine the sexual health needs, concerns, and stressors facing young TMSM (n = 12; mean age = 23.8 years; 16.7% people of color). Next, LS4M was pilot tested (n = 17; mean age = 24.3 years; 23.5% people of color) to assess acceptability with the study population and feasibility of all study procedures. Overall attendance, participation rates, and positive feedback from participants demonstrate that LS4M is highly acceptable and feasible to carry out with young TMSM. Trends in outcome measures across 4 months of follow-up suggest that participation in the intervention may improve mental health, reduce internalized stigma, and reduce HIV- and STI-related risk behaviors. Further testing of the intervention enrolling young TMSM with recent sexual risk behavior at baseline and with a control group is warranted. Lessons learned for future work with young TMSM are discussed.

  3. Studies with pyrethroids (kadethrin and deltamethrin) and lindane in ethanol sensitive (LS) and insensitive (SS) mouse strains

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Doherty, J.; Baker, R.C.; Deitrich, R.

    1990-02-26

    Ethanol (E) sensitive (LS) and insensitive (SS) mouse strains are distinguished by their sleeping time to a given dose of E and the locus for this difference is at the level of the neuron. In attempts to understand the neuropharmacological basis of insecticide action and to further define the differences in these mouse lines, LS and SS mice were dosed with type I (kadethrine, K) and II (deltamethrin, D) pyrethroids and lindane (L). These compounds were selected because their proposed modes of action are on the Na+ channel (K and D) and/or the GABA receptor ionophore (D and L). Nomore » consistent differences in the effects of K, D or L in the SS and LS mouse lines were evident. In preliminary studies both SS and LS mice dosed with 50 or 100 {mu}g/brain of L (intracerebroventricularly) but not D slept much longer (2-3X) than when dosed with E alone, an effect opposite of that predicted from L's known excitatory action. These data indicate that as far as can be distinguished by pyrethroids and L, the Na+ channel and GABA receptor/ionophore complex are similar in both the LS and SS mouse lines.« less

  4. TES/Aura L2 Ozone (O3) Limb V6 (TL2O3LS)

    Atmospheric Science Data Center

    2018-03-01

    TES/Aura L2 Ozone (O3) Limb (TL2O3LS) News:  TES News Join ... Project Title:  TES Discipline:  Tropospheric Composition Version:  V6 Level:  L2 Platform:  TES/Aura L2 Ozone Spatial Coverage:  27 x 23 km Limb Spatial ...

  5. 76 FR 68804 - New York Disaster Number NY-00113

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12858 and 12859] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the State of New York, dated 09/23/2011, is hereby amended to include the following areas as adversely...

  6. 76 FR 62131 - New York Disaster Number NY-00113

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12858 and 12859] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance only for the State of New York... the State of New York, dated 09/23/2011, is hereby amended to include the following areas as adversely...

  7. 76 FR 64420 - New York Disaster Number NY-00113

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12858 and 12859] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the State of New York, dated 09/23/2011, is hereby amended to include the following areas as adversely...

  8. 76 FR 67245 - New York Disaster Number NY-00113

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12858 and 12859] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the State of New York, dated 09/23/2011, is hereby amended to include the following areas as adversely...

  9. 76 FR 63699 - New York Disaster Number NY-00113

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12858 and 12859] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the State of New York, dated 09/23/2011, is hereby amended to include the following areas as adversely...

  10. 76 FR 66111 - New York Disaster Number NY-00113

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12858 and 12859] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the State of New York, dated 09/23/2011, is hereby amended to include the following areas as adversely...

  11. DISCOVERY OF EXTENDED AND VARIABLE RADIO STRUCTURE FROM THE GAMMA-RAY BINARY SYSTEM PSR B1259-63/LS 2883

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moldon, Javier; Ribo, Marc; Paredes, Josep M.

    2011-05-01

    PSR B1259-63 is a 48 ms pulsar in a highly eccentric 3.4 year orbit around the young massive star LS 2883. During the periastron passage the system displays transient non-thermal unpulsed emission from radio to very high energy gamma rays. It is one of the three galactic binary systems clearly detected at TeV energies, together with LS 5039 and LS I +61 303. We observed PSR B1259-63 after the 2007 periastron passage with the Australian Long Baseline Array at 2.3 GHz to trace the milliarcsecond (mas) structure of the source at three different epochs. We have discovered extended and variablemore » radio structure. The peak of the radio emission is detected outside the binary system near periastron, at projected distances of 10-20 mas (25-45 AU assuming a distance of 2.3 kpc). The total extent of the emission is {approx}50 mas ({approx}120 AU). This is the first observational evidence that non-accreting pulsars orbiting massive stars can produce variable extended radio emission at AU scales. Similar structures are also seen in LS 5039 and LS I +61 303, in which the nature of the compact object is unknown. The discovery presented here for the young non-accreting pulsar PSR B1259-63 reinforces the link with these two sources and supports the presence of pulsars in these systems as well. A simple kinematical model considering only a spherical stellar wind can approximately trace the extended structures if the binary system orbit has a longitude of the ascending node of {Omega} {approx} -40{sup 0} and a magnetization parameter of {sigma} {approx} 0.005.« less

  12. A RADIO PULSAR SEARCH OF THE {gamma}-RAY BINARIES LS I +61 303 AND LS 5039

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Virginia McSwain, M.; Ray, Paul S.; Ransom, Scott M.

    2011-09-01

    LS I +61 303 and LS 5039 are exceptionally rare examples of high-mass X-ray binaries with MeV-TeV emission, making them two of only five known '{gamma}-ray binaries'. There has been disagreement within the literature over whether these systems are microquasars, with stellar winds accreting onto a compact object to produce high energy emission and relativistic jets, or whether their emission properties might be better explained by a relativistic pulsar wind colliding with the stellar wind. Here we present an attempt to detect radio pulsars in both systems with the Green Bank Telescope. The upper limits of flux density are betweenmore » 4.1 and 14.5 {mu}Jy, and we discuss the null results of the search. Our spherically symmetric model of the wind of LS 5039 demonstrates that any pulsar emission will be strongly absorbed by the dense wind unless there is an evacuated region formed by a relativistic colliding wind shock. LS I +61 303 contains a rapidly rotating Be star whose wind is concentrated near the stellar equator. As long as the pulsar is not eclipsed by the circumstellar disk or viewed through the densest wind regions, detecting pulsed emission may be possible during part of the orbit.« less

  13. 7 CFR 1779.21-1779.23 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1779.21-1779.23 Section 1779.21-1779.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS §§ 1779.21-1779.23 [Reserved] ...

  14. Influence of Terraced area DEM Resolution on RUSLE LS Factor

    NASA Astrophysics Data System (ADS)

    Zhang, Hongming; Baartman, Jantiene E. M.; Yang, Xiaomei; Gai, Lingtong; Geissen, Viollette

    2017-04-01

    Topography has a large impact on the erosion of soil by water. Slope steepness and slope length are combined (the LS factor) in the universal soil-loss equation (USLE) and its revised version (RUSLE) for predicting soil erosion. The LS factor is usually extracted from a digital elevation model (DEM). The grid size of the DEM will thus influence the LS factor and the subsequent calculation of soil loss. Terracing is considered as a support practice factor (P) in the USLE/RUSLE equations, which is multiplied with the other USLE/RUSLE factors. However, as terraces change the slope length and steepness, they also affect the LS factor. The effect of DEM grid size on the LS factor has not been investigated for a terraced area. We obtained a high-resolution DEM by unmanned aerial vehicles (UAVs) photogrammetry, from which the slope steepness, slope length, and LS factor were extracted. The changes in these parameters at various DEM resolutions were then analysed. The DEM produced detailed LS-factor maps, particularly for low LS factors. High (small valleys, gullies, and terrace ridges) and low (flats and terrace fields) spatial frequencies were both sensitive to changes in resolution, so the areas of higher and lower slope steepness both decreased with increasing grid size. Average slope steepness decreased and average slope length increased with grid size. Slope length, however, had a larger effect than slope steepness on the LS factor as the grid size varied. The LS factor increased when the grid size increased from 0.5 to 30-m and increased significantly at grid sizes >5-m. The LS factor was increasingly overestimated as grid size decreased. The LS factor decreased from grid sizes of 30 to 100-m, because the details of the terraced terrain were gradually lost, but the factor was still overestimated.

  15. A gene encoding an abscisic acid biosynthetic enzyme (LsNCED4) collocates with the high temperature germination locus Htg6.1 in lettuce (Lactuca sp.)

    PubMed Central

    Argyris, Jason; Truco, María José; Ochoa, Oswaldo; McHale, Leah; Dahal, Peetambar; Van Deynze, Allen; Michelmore, Richard W.

    2010-01-01

    Thermoinhibition, or failure of seeds to germinate when imbibed at warm temperatures, can be a significant problem in lettuce (Lactuca sativa L.) production. The reliability of stand establishment would be improved by increasing the ability of lettuce seeds to germinate at high temperatures. Genes encoding germination- or dormancy-related proteins were mapped in a recombinant inbred line population derived from a cross between L. sativa cv. Salinas and L. serriola accession UC96US23. This revealed several candidate genes that are located in the genomic regions containing quantitative trait loci (QTLs) associated with temperature and light requirements for germination. In particular, LsNCED4, a temperature-regulated gene in the biosynthetic pathway for abscisic acid (ABA), a germination inhibitor, mapped to the center of a previously detected QTL for high temperature germination (Htg6.1) from UC96US23. Three sets of sister BC3S2 near-isogenic lines (NILs) that were homozygous for the UC96US23 allele of LsNCED4 at Htg6.1 were developed by backcrossing to cv. Salinas and marker-assisted selection followed by selfing. The maximum temperature for germination of NIL seed lots with the UC96US23 allele at LsNCED4 was increased by 2–3°C when compared with sister NIL seed lots lacking the introgression. In addition, the expression of LsNCED4 was two- to threefold lower in the former NIL lines as compared to expression in the latter. Together, these data strongly implicate LsNCED4 as the candidate gene responsible for the Htg6.1 phenotype and indicate that decreased ABA biosynthesis at high imbibition temperatures is a major factor responsible for the increased germination thermotolerance of UC96US23 seeds. Electronic supplementary material The online version of this article (doi:10.1007/s00122-010-1425-3) contains supplementary material, which is available to authorized users. PMID:20703871

  16. 7 CFR 634.23 - Water quality plan.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Water quality plan. 634.23 Section 634.23 Agriculture... AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Participant RCWP Contracts § 634.23 Water quality plan. (a) The participant's water quality plan, developed with technical assistance by the NRCS or its...

  17. 7 CFR 634.23 - Water quality plan.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Water quality plan. 634.23 Section 634.23 Agriculture... AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Participant RCWP Contracts § 634.23 Water quality plan. (a) The participant's water quality plan, developed with technical assistance by the NRCS or its...

  18. 7 CFR 634.23 - Water quality plan.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Water quality plan. 634.23 Section 634.23 Agriculture... AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Participant RCWP Contracts § 634.23 Water quality plan. (a) The participant's water quality plan, developed with technical assistance by the NRCS or its...

  19. 23 CFR 627.7 - VE programs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false VE programs. 627.7 Section 627.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS VALUE ENGINEERING § 627.7 VE programs. (a) The STA shall establish and sustain a VE program under which VE analyses are...

  20. 23 CFR 627.7 - VE programs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false VE programs. 627.7 Section 627.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS VALUE ENGINEERING § 627.7 VE programs. (a) The STA shall establish and sustain a VE program under which VE analyses are...

  1. 7 CFR 634.23 - Water quality plan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... quality management plan. Such BMP's must reduce the amount of pollutants that enter a stream or lake by... 7 Agriculture 6 2010-01-01 2010-01-01 false Water quality plan. 634.23 Section 634.23 Agriculture... AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Participant RCWP Contracts § 634.23 Water quality...

  2. Testing Two Alternative Pathological Personality Measures in the Assessment of Psychopathy: An Examination of the Snap and DAPP-BQ.

    PubMed

    Pryor, Lauren R; Miller, Joshua D; Gaughan, Eric T

    2009-02-01

    The current study examined the interrelations between two measures of pathological personality, the Schedule for Nonadaptive and Adaptive Personality (SNAP; Clark, 1993) and the Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ; Livesley, 1990), and their respective relations with psychopathy. Two hundred and twenty-nine undergraduate students completed the SNAP, DAPP-BQ, and two self-report psychopathy inventories, the Levenson Self-Report Psychopathy Scale (LSRP; Levenson, Kiehl, & Fitzpatrick, 1995) and the Psychopathic Personality Inventory-Revised (PPI-R; Lilienfeld & Widows, 2005). Results revealed good convergence between conceptually related SNAP and DAPP-BQ subscales. Both the SNAP and DAPP-BQ accounted for a substantial amount of variance in psychopathy scores although the DAPP-BQ accounted for a larger percentage of the variance and demonstrated greater incremental validity. Results suggest that both measures can be successfully used to assess traits associated with psychopathy.

  3. Mars at Ls 211°: Elysium/Mare Cimmerium

    NASA Image and Video Library

    2005-05-24

    This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 211° during a previous Mars year. This month, Mars looks similar, as Ls 211° occurred in mid-May 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360° around the Sun in 1 Mars year. The year begins at Ls 0°, the start of northern spring and southern autumn. http://photojournal.jpl.nasa.gov/catalog/PIA07988

  4. Mars at Ls 160o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 160o during a previous Mars year. This month, Mars looks similar, as Ls 160o occurred in mid-February 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o--the start of northern spring and southern summer.

    Season: Northern Summer/Southern Winter

  5. Mars at Ls 66o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    27 June 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 66o during a previous Mars year. This month, Mars looks similar, as Ls 66o occurred in mid-June 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Northern Spring/Southern Autumn

  6. 7 CFR 23.13 - Plan of Work.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Plan of Work. 23.13 Section 23.13 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.13 Plan of Work. (a) A Regional Plan of Work for carrying out the programs authorized to be funded under...

  7. 7 CFR 23.6 - Plan of Work.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Plan of Work. 23.6 Section 23.6 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK State Program § 23.6 Plan of Work. (a) A State Annual Plan of Work for carrying out the programs authorized under title V shall be...

  8. 7 CFR 23.6 - Plan of Work.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Plan of Work. 23.6 Section 23.6 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK State Program § 23.6 Plan of Work. (a) A State Annual Plan of Work for carrying out the programs authorized under title V shall be...

  9. 7 CFR 23.12 - Availability of funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Availability of funds. 23.12 Section 23.12 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.12... Programs for expenditures authorized by section 503(c) of title V, in the fiscal year for which the funds...

  10. 23 CFR 924.7 - Program structure.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Program structure. 924.7 Section 924.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HIGHWAY SAFETY HIGHWAY SAFETY IMPROVEMENT PROGRAM... implementation through highway safety improvement projects. The HSIP includes construction and operational...

  11. 23 CFR 924.7 - Program structure.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Program structure. 924.7 Section 924.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HIGHWAY SAFETY HIGHWAY SAFETY IMPROVEMENT PROGRAM... implementation through highway safety improvement projects. The HSIP includes construction and operational...

  12. Optical Observations of BQ Cam (V 0332+53) During Outburst

    NASA Astrophysics Data System (ADS)

    Ozbey Arabaci, Mehtap; Beklen, Elif; Donmez, Burcin; Shameoni Niaei, Mohammad

    2016-10-01

    Recent MAXI/GSC observations reported an X-ray brightening of the Be/X-ray system V 0332+53 (ATel #9596). Following this report, we performed optical spectroscopic and photometric observations of BQ Cam, identified as the optical counterpart of the system, with the 1.5 m Russian-Turkish telescope of TUBITAK National Observatory (Antalya, Turkey) on 2016 October 6 (MJD 57667).

  13. Mars at Ls 79o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    11 July 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 79o during a previous Mars year. This month, Mars looks similar, as Ls 79o occurs in mid-July 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  14. Mars at Ls 12o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    28 February 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 12o during a previous Mars year. This month, Mars looks similar, as Ls 12o occurred in mid-February 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  15. Mars at Ls 12o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    15 February 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 12o during a previous Mars year. This month, Mars looks similar, as Ls 12o occurs in mid-February 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  16. Mars at Ls 25o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    28 March 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 25o during a previous Mars year. This month, Mars looks similar, as Ls 25o occurred in mid-March 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  17. Mars at Ls 53o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    9 May 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 53o during a previous Mars year. This month, Mars looks similar, as Ls 53o occurs in mid-May 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  18. Mars at Ls 230o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    28 June 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 230o during a previous Mars year. This month, Mars looks similar, as Ls 230o occurred in mid-June 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season Northern Autumn/Southern Spring

  19. Mars at Ls 249o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    26 July 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 249o during a previous Mars year. This month, Mars looks similar, as Ls 249o occurred in mid-July 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Autumn/Southern Spring

  20. Mars at Ls 66o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    13 June 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 66o during a previous Mars year. This month, Mars looks similar, as Ls 66o occurs in mid-June 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  1. Mars at Ls 176°: Acidalia/Mare Erythraeum

    NASA Image and Video Library

    2005-03-08

    This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 176° during a previous Mars year. This month, Mars looks similar, as Ls 176° occurs in mid-March 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360° around the Sun in 1 Mars year. The year begins at Ls 0°, the start of northern spring and southern autumn. Season: Northern Summer/Southern Winter. http://photojournal.jpl.nasa.gov/catalog/PIA07443

  2. Mars at Ls 288o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    13 September 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 288o during a previous Mars year. This month, Mars looks similar, as Ls 288o occurs in mid-September 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  3. Mars at Ls 324o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    22 November 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 324o during a previous Mars year. This month, Mars looks similar, as Ls 324o occurred in mid-November 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  4. Mars at Ls 306o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    11 October 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 306o during a previous Mars year. This month, Mars looks similar, as Ls 306o occurs in mid-October 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  5. Mars at Ls 39o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    11 April 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 39o during a previous Mars year. This month, Mars looks similar, as Ls 39o occurs in mid-April 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  6. Mars at Ls 341o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    27 December 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 341o during a previous Mars year. This month, Mars looks similar, as Ls 341o occurred in mid-December 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  7. Mars at Ls 211o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    10 May 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 211o during a previous Mars year. This month, Mars looks similar, as Ls 211o occurs in mid-May 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Autumn/Southern Spring

  8. Mars at Ls 324o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    8 November 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 324o during a previous Mars year. This month, Mars looks similar, as Ls 324o occurs in mid-November 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  9. Mars at Ls 193o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    26 April 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 193o during a previous Mars year. This month, Mars looks similar, as Ls 193o occurred in mid-April 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern summer.

    Season: Northern Autumn/Southern Spring

  10. Mars at Ls 25o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    14 March 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 25o during a previous Mars year. This month, Mars looks similar, as Ls 25o occurs in mid-March 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  11. Mars at Ls 176o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    8 March 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 176o during a previous Mars year. This month, Mars looks similar, as Ls 176o occurs in mid-March 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Summer/Southern Winter

  12. Mars at Ls 288o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    27 September 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 288o during a previous Mars year. This month, Mars looks similar, as Ls 288o occurred in mid-September 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  13. Mars at Ls 357o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    25 January 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 357o during a previous Mars year. This month, Mars looks similar, as Ls 357o occurred in mid-January 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  14. Mars at Ls 39o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    25 April 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 39o during a previous Mars year. This month, Mars looks similar, as Ls 39o occurred in mid-April 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  15. Mars at Ls 230o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    14 June 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 230o during a previous Mars year. This month, Mars looks similar, as Ls 230o occurs in mid-June 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Autumn/Southern Spring

  16. Mars at Ls 269o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    9 August 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 269o during a previous Mars year. This month, Mars looks similar, as Ls 269o occurs in mid-August 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: last days of Northern Autumn/Southern Spring

  17. Mars at Ls 160o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    8 February 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 160o during a previous Mars year. This month, Mars looks similar, as Ls 160o occurs in mid-February 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o--the start of northern spring and southern summer.

    Season: Northern Summer/Southern Winter

  18. Mars at Ls 93o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    8 August 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 93o during a previous Mars year. This month, Mars looks similar, as Ls 93o occurs in mid-August 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Summer/Southern Winter

  19. Mars at Ls 306o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    25 October 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 306o during a previous Mars year. This month, Mars looks similar, as Ls 306o occurred in mid-October 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  20. Mars at Ls 79o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    25 July 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 79o during a previous Mars year. This month, Mars looks similar, as Ls 79o occurred in mid-July 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Spring/Southern Autumn

  1. Mars at Ls 107o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    13 September 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 107o during a previous Mars year. This month, Mars looks similar, as Ls 107o occurs in mid-September 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Summer/Southern Winter

  2. Mars at Ls 357o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2006-01-01

    10 January 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 357o during a previous Mars year. This month, Mars looks similar, as Ls 357o occurs in mid-January 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Winter/Southern Summer

  3. Mars at Ls 249o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    12 July 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 249o during a previous Mars year. This month, Mars looks similar, as Ls 249o occurs in mid-July 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Season: Northern Autumn/Southern Spring

  4. 30 CFR 23.7 - Specific requirements for approval.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS TELEPHONES AND SIGNALING DEVICES § 23.7 Specific requirements for... apply. (g) Line powered telephones and signaling devices or systems shall be equipped with standby power... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Specific requirements for approval. 23.7...

  5. 30 CFR 23.7 - Specific requirements for approval.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS TELEPHONES AND SIGNALING DEVICES § 23.7 Specific requirements for... apply. (g) Line powered telephones and signaling devices or systems shall be equipped with standby power... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Specific requirements for approval. 23.7...

  6. 30 CFR 23.7 - Specific requirements for approval.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS TELEPHONES AND SIGNALING DEVICES § 23.7 Specific requirements for... apply. (g) Line powered telephones and signaling devices or systems shall be equipped with standby power... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Specific requirements for approval. 23.7...

  7. Manual for LS-DYNA Wood Material Model 143

    DOT National Transportation Integrated Search

    2007-08-01

    An elastoplastic damage model with rate effects was developed for wood and was implemented into LS-DYNA, a commercially available finite element code. This manual documents the theory of the wood material model, describes the LS-DYNA input and output...

  8. 7 CFR 4285.4-4285.23 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false [Reserved] 4285.4-4285.23 Section 4285.4-4285.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE AGREEMENTS Federal-State Research on...

  9. 7 CFR 966.23 - Term of office.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Term of office. 966.23 Section 966.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE TOMATOES GROWN IN FLORIDA Order...

  10. 7 CFR 945.23 - Redistricting and reapportionment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Redistricting and reapportionment. 945.23 Section 945... Handling Administrative Committee § 945.23 Redistricting and reapportionment. (a) The Secretary, upon... administration due to redistricting or reapportionment of members within districts; and (5) other relevant...

  11. 7 CFR 945.23 - Redistricting and reapportionment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Redistricting and reapportionment. 945.23 Section 945... Handling Administrative Committee § 945.23 Redistricting and reapportionment. (a) The Secretary, upon... administration due to redistricting or reapportionment of members within districts; and (5) other relevant...

  12. 78 FR 27414 - New York; Major Disaster and Related Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    .... FEMA-4111-DR; Docket ID FEMA-2013-0001] New York; Major Disaster and Related Determinations AGENCY... declaration of a major disaster for the State of New York (FEMA-4111-DR), dated April 23, 2013, and related... Act''), as follows: I have determined that the damage in certain areas of the State of New York...

  13. X-ray Spectral Analysis of the Cataclysmic Variable LS Peg using XMM-Newton Observatory Data

    NASA Astrophysics Data System (ADS)

    Talebpour Sheshvan, N.; Nabizadeh, A.; Balman, S.

    2017-10-01

    LS Peg is a Cataclysmic Variable (CV) suggested as Intermediate Polar (IP) because of similar properties to those observed in IP systems. We used archival XMM-Newton observation of LS Peg in order to study the X-ray characteristics of the system. We show LS Peg light curves in several different energy bands, and discuss about orbital modulations and power spectral analysis. Unlike the previous spectral analysis of the EPIC-MOS data by fitting a hot optically thin plasma emission model with a single temperature, we simultaneously fit EPIC spectrum (pn+MOS) using a composite model of absorption (tbabs) along with two different partial covering absorbers plus a multi-temperature plasma emission component in XSPEC. In addition, we find a Gaussian emission line at 6.4 keV. For LS Peg the maximum temperature of the plasma distribution is found to be ˜ 17.8 keV with a luminosity of ˜ 7.4×10^{32}erg s^{-1} translating to an accretion rate of ˜ 1.7×10 ^{-10} M_{⊙} yr^{-1}. We present spectra for orbital minimum and orbital maximum. In addition, we use SWIFT observations of the source in order to make a comparison. We elaborate on the geometry of accretion and absorption in the X-ray emitting region with articulation on the magnetic nature.

  14. Mars at Ls 193°: Acidalia/Mare Erythraeum

    NASA Image and Video Library

    2005-04-12

    This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 193° during a previous Mars year. This month, Mars looks similar, as Ls 193° occurs in mid-April 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360° around the Sun in 1 Mars year. The year begins at Ls 0°, the start of northern spring and southern autumn. Location near: 47.3°N, 294.0°W Image width: ~3 km (~1.9 mi) Illumination from: lower left Season: Northern Summer. http://photojournal.jpl.nasa.gov/catalog/PIA07837

  15. Mars at Ls 53°: Acidalia/Mare Erythraeum

    NASA Image and Video Library

    2006-05-09

    This picture is a composite of MOC daily global images acquired at Ls 53° during a previous Mars year. This month, Mars looks similar, as Ls 53° occurs in mid-May 2006. The picture shows the Acidalia/Mare Erythraeum face of Mars

  16. 7 CFR 15b.23 - Educational setting.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Educational setting. 15b.23 Section 15b.23 Agriculture Office of the Secretary of Agriculture NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... handicapped person. A recipient shall place a handicapped person in the regular educational environment...

  17. 7 CFR 15b.23 - Educational setting.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Educational setting. 15b.23 Section 15b.23 Agriculture Office of the Secretary of Agriculture NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... handicapped person. A recipient shall place a handicapped person in the regular educational environment...

  18. 7 CFR 15b.23 - Educational setting.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Educational setting. 15b.23 Section 15b.23 Agriculture Office of the Secretary of Agriculture NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... handicapped person. A recipient shall place a handicapped person in the regular educational environment...

  19. 7 CFR 15b.23 - Educational setting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Educational setting. 15b.23 Section 15b.23 Agriculture Office of the Secretary of Agriculture NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... handicapped person. A recipient shall place a handicapped person in the regular educational environment...

  20. 7 CFR 15b.23 - Educational setting.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false Educational setting. 15b.23 Section 15b.23 Agriculture Office of the Secretary of Agriculture NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... handicapped person. A recipient shall place a handicapped person in the regular educational environment...

  1. 23 CFR 190.7 - Processing of claims.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Processing of claims. 190.7 Section 190.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES INCENTIVE PAYMENTS FOR CONTROLLING OUTDOOR ADVERTISING ON THE INTERSTATE SYSTEM § 190.7 Processing of claims. Audited and approved PR...

  2. 23 CFR 190.7 - Processing of claims.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Processing of claims. 190.7 Section 190.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES INCENTIVE PAYMENTS FOR CONTROLLING OUTDOOR ADVERTISING ON THE INTERSTATE SYSTEM § 190.7 Processing of claims. Audited and approved PR...

  3. 23 CFR 190.7 - Processing of claims.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Processing of claims. 190.7 Section 190.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES INCENTIVE PAYMENTS FOR CONTROLLING OUTDOOR ADVERTISING ON THE INTERSTATE SYSTEM § 190.7 Processing of claims. Audited and approved PR...

  4. 23 CFR 190.7 - Processing of claims.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Processing of claims. 190.7 Section 190.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES INCENTIVE PAYMENTS FOR CONTROLLING OUTDOOR ADVERTISING ON THE INTERSTATE SYSTEM § 190.7 Processing of claims. Audited and approved PR...

  5. Mars at Ls 93o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2006-01-01

    22 August 2006 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 93o during a previous Mars year. This month, Mars looks similar, as Ls 93o occurred in mid-August 2006. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Location near: 86.1oN, 208.5oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Summer/Southern Winter

  6. Mars at Ls 176o: Elysium/Mare Cimmerium

    NASA Technical Reports Server (NTRS)

    2005-01-01

    22 March 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 176o during a previous Mars year. This month, Mars looks similar, as Ls 176o occurred in mid-March 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Location near: 79.1oN, 228.8oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Summer/Southern Winter

  7. Mars at Ls 193o: Acidalia/Mare Erythraeum

    NASA Technical Reports Server (NTRS)

    2005-01-01

    12 April 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 193o during a previous Mars year. This month, Mars looks similar, as Ls 193o occurs in mid-April 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn.

    Location near: 47.3oN, 294.0oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Summer

  8. 23 CFR 1.7 - Urban area boundaries.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Urban area boundaries. 1.7 Section 1.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.7 Urban area boundaries. Boundaries of an urban area shall be submitted by the State highway department...

  9. 23 CFR 1.7 - Urban area boundaries.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Urban area boundaries. 1.7 Section 1.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.7 Urban area boundaries. Boundaries of an urban area shall be submitted by the State highway department...

  10. 23 CFR 1.7 - Urban area boundaries.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Urban area boundaries. 1.7 Section 1.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.7 Urban area boundaries. Boundaries of an urban area shall be submitted by the State highway department...

  11. 23 CFR 1.7 - Urban area boundaries.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Urban area boundaries. 1.7 Section 1.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.7 Urban area boundaries. Boundaries of an urban area shall be submitted by the State highway department...

  12. 30 CFR 7.23 - Application requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... APPROVAL OF MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Brattice Cloth and Ventilation Tubing § 7.23 Application requirements. (a) Brattice cloth. A single application may address two or more...

  13. 30 CFR 7.23 - Application requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... APPROVAL OF MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Brattice Cloth and Ventilation Tubing § 7.23 Application requirements. (a) Brattice cloth. A single application may address two or more...

  14. 30 CFR 7.23 - Application requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... APPROVAL OF MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Brattice Cloth and Ventilation Tubing § 7.23 Application requirements. (a) Brattice cloth. A single application may address two or more...

  15. Extension of a GIS procedure for calculating the RUSLE equation LS factor

    NASA Astrophysics Data System (ADS)

    Zhang, Hongming; Yang, Qinke; Li, Rui; Liu, Qingrui; Moore, Demie; He, Peng; Ritsema, Coen J.; Geissen, Violette

    2013-03-01

    The Universal Soil Loss Equation (USLE) and revised USLE (RUSLE) are often used to estimate soil erosion at regional landscape scales, however a major limitation is the difficulty in extracting the LS factor. The geographic information system-based (GIS-based) methods which have been developed for estimating the LS factor for USLE and RUSLE also have limitations. The unit contributing area-based estimation method (UCA) converts slope length to unit contributing area for considering two-dimensional topography, however is not able to predict the different zones of soil erosion and deposition. The flowpath and cumulative cell length-based method (FCL) overcomes this disadvantage but does not consider channel networks and flow convergence in two-dimensional topography. The purpose of this research was to overcome these limitations and extend the FCL method through inclusion of channel networks and convergence flow. We developed LS-TOOL in Microsoft's.NET environment using C♯ with a user-friendly interface. Comparing the LS factor calculated with the three methodologies (UCA, FCL and LS-TOOL), LS-TOOL delivers encouraging results. In particular, LS-TOOL uses breaks in slope identified from the DEM to locate soil erosion and deposition zones, channel networks and convergence flow areas. Comparing slope length and LS factor values generated using LS-TOOL with manual methods, LS-TOOL corresponds more closely with the reality of the Xiannangou catchment than results using UCA or FCL. The LS-TOOL algorithm can automatically calculate slope length, slope steepness, L factor, S factor, and LS factors, providing the results as ASCII files which can be easily used in some GIS software. This study is an important step forward in conducting more accurate large area erosion evaluation.

  16. Chromosome Rearrangements in Cornelia de Lange Syndrome (CdLS): Report of a der(3)t(3;12)(p25.3;p13.3) in Two Half Sibs With Features of CdLS and Review of Reported CdLS Cases With Chromosome Rearrangements

    PubMed Central

    DeScipio, Cheryl; Kaur, Maninder; Yaeger, Dinah; Innis, Jeffrey W.; Spinner, Nancy B.; Jackson, Laird G.; Krantz, Ian D.

    2016-01-01

    Cornelia de Lange syndrome (CdLS; OMIM 122470) is a dominantly inherited disorder characterized by multisystem involvement, cognitive delay, limb defects, and characteristic facial features. Recently, mutations in NIPBL have been found in ~50% of individuals with CdLS. Numerous chromosomal rearrangements have been reported in individuals with CdLS. These rearrangements may be causative of a CdLS phenotype, result in a phenocopy, or be unrelated to the observed phenotype. We describe two half siblings with a der(3)t(3;12)(p25.3;p13.3) chromosomal rearrangement, clinical features resembling CdLS, and phenotypic overlap with the del(3)(p25) phenotype. Region-specific BAC probes were used to fine-map the breakpoint region by fluorescence in situ hybridization (FISH). FISH analysis places the chromosome 3 breakpoint distal to RP11-115G3 on 3p25.3; the chromosome 12 breakpoint is distal to BAC RP11-88D16 on 12p13.3. A review of published cases of terminal 3p deletions and terminal 12p duplications indicates that the findings in these siblings are consistent with the del(3)(p25) phenotype. Given the phenotypic overlap with CdLS, we have reviewed the reported cases of chromosomal rearrangements involved in CdLS to better elucidate other potential loci that could harbor additional CdLS genes. Additionally, to identify chromosome rearrangements, genome-wide array comparative genomic hybridization (CGH) was performed on eight individuals with typical CdLS and without identifiable deletion or mutation of NIPBL. No pathologic rearrangements were identified. PMID:16075459

  17. Floods of 2011 in New York

    USGS Publications Warehouse

    Lumia, Richard; Firda, Gary D.; Smith, Travis L.

    2014-01-01

    Record rainfall combined with above-average temperatures and substantial spring snowmelt resulted in record flooding throughout New York during 2011. Rainfall totals in eastern New York were the greatest since 1895 and as much as 60 percent above the long-term average within the Catskill Mountains area and the Susquehanna River Basin. This report documents the three largest storms and resultant flooding during the year: (1) spring storm during April and May, (2) Tropical Storm Irene during August, and (3) remnants of Tropical Storm Lee during September. According to the Federal Emergency Management Agency (FEMA), the cost of these three storms exceeded $1 billion in Federal disaster assistance. A warm and wet spring in northern New York resulted in record flooding at 21 U.S. Geological Survey (USGS) active streamgages during late April to early May with the annual exceedance probabilities (AEPs) of 11 peak discharges equaling or exceeding 1 percent. Nearly 5 inches of rain during late April combined with a rapidly melting snowpack caused widespread flooding throughout northern New York, resulting in many road closures, millions of dollars in damages, and 23 counties declared disaster areas and eligible for public assistance. On May 6, Lake Champlain recorded its highest lake level in over 140 years. Hurricane Irene entered New York State on August 28 as a tropical storm and traveled up the eastern corridor of the State, leaving a path of destruction and damage never seen in many parts of New York. Thirty-one counties in New York were declared disaster areas with damages of over $1.3 billion dollars and 10 reported deaths. Storm rainfall exceeded 18 inches in the Catskill Mountains area of southeastern New York with many other areas of eastern New York receiving over 7 inches. Catastrophic flooding resulted from the extreme rainfall in many locations, including Schoharie Creek and its tributaries, the eastern Delaware River Basin, the Ausable and Bouquet River

  18. 23 CFR 1350.7 - Post-award requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Post-award requirements. 1350.7 Section 1350.7 Highways... MOTORCYCLIST SAFETY PROGRAM § 1350.7 Post-award requirements. (a) Within 30 days after notification of award but in no event later than September 12 of each year, a State must submit electronically to the agency...

  19. 23 CFR 1350.7 - Post-award requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Post-award requirements. 1350.7 Section 1350.7 Highways... MOTORCYCLIST SAFETY PROGRAM § 1350.7 Post-award requirements. (a) Within 30 days after notification of award but in no event later than September 12 of each year, a State must submit electronically to the agency...

  20. 23 CFR 1350.7 - Post-award requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Post-award requirements. 1350.7 Section 1350.7 Highways... MOTORCYCLIST SAFETY PROGRAM § 1350.7 Post-award requirements. (a) Within 30 days after notification of award but in no event later than September 12 of each year, a State must submit electronically to the agency...

  1. 23 CFR 1215.7 - Transfer of funds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Transfer of funds. 1215.7 Section 1215.7 Highways... TRANSPORTATION GUIDELINES USE OF SAFETY BELTS-COMPLIANCE AND TRANSFER-OF-FUNDS PROCEDURES § 1215.7 Transfer of funds. (a) Except as provided in paragraph (b) of this section, if at any time in a fiscal year...

  2. Symmetric and anti-symmetric LS hyperon potentials from lattice QCD

    NASA Astrophysics Data System (ADS)

    Ishii, Noriyoshi; Murano, Keiko; Nemura, Hidekatsu; Sasaki, Kenji; Inoue, Takashi; HAL QCD Collaboration

    2014-09-01

    We present recent results of odd-parity hyperon-hyperon potentials from lattice QCD. By using HAL QCD method, we generate hyperon-hyperon potentials from Nambu-Bethe-Salpeter (NBS) wave functions generated by lattice QCD simulation in the flavor SU(3) limit. Potentials in the irreducible flavor SU(3) representations are combined to make a Lambda-N potential which has a strong symmetric LS potential and a weak anti-symmetric LS potential. We discuss a possible cancellation between symmetric and anti-symmetric LS (Lambda-N) potentials after the coupled Sigma-N sector is integrated out. We present recent results of odd-parity hyperon-hyperon potentials from lattice QCD. By using HAL QCD method, we generate hyperon-hyperon potentials from Nambu-Bethe-Salpeter (NBS) wave functions generated by lattice QCD simulation in the flavor SU(3) limit. Potentials in the irreducible flavor SU(3) representations are combined to make a Lambda-N potential which has a strong symmetric LS potential and a weak anti-symmetric LS potential. We discuss a possible cancellation between symmetric and anti-symmetric LS (Lambda-N) potentials after the coupled Sigma-N sector is integrated out. This work is supported by JSPS KAKENHI Grant Number 25400244.

  3. Today's Environmental Technologies-Innovative Solutions for Regional Issues, U.S. EPA ETV and SBIR Programs Regional Workshop, October 7-8, 2008, U.S. EPA Region 2, New York City, New York, Meeting Summary Report

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) Environmental Technology Verification (ETV) and Small Business Innovation Research (SBIR) Programs hosted a workshop on October 7–8, 2008, at the EPA Region 2 office in New York City, New York. The goals of the workshop were to: (1) ...

  4. SOFIA/FIFI-LS Observations of Galactic PDRs

    NASA Astrophysics Data System (ADS)

    Klein, Randolf; Reedy, Alexander; Colditz, Sebastian; Fadda, Dario; Fischer, Chrisitan; Geis, Norbert; Hönle, Rainer; Iserlohe, Christof; Krabbe, Alfred; Looney, Leslie; Poglitsch, Albrecht; Raab, Walfried; Rebel, Felix; Vacca, William

    2018-01-01

    Photo-dissociation regions or photon-dominated regions (PDRs) are the interfaces between ionized HII-regions and adjacent molecular clouds usually found in massive star-forming regions. As the places where molecular clouds are destroyed by the UV radiation of the forming massive stars, they are the regions where the effects of star formation on the interstellar medium and the energetics and physical properties of the feedback can be best studied.FIFI-LS, SOFIA's far-infrared (FIR) spectrometer, is well suited to observe galactic PDRs and study them in great detail. The bulk of the energy from PDRs is emitted in the wavelength range of FIFI-LS, which ranges from 50 to 200µm. In this wavelength range, there are many strong atomic and ionic fine-structure lines, which can serve as diagnostic tools to trace these species and to determine densities and temperatures of the ionized and neutral medium in PDRs. FIFI-LS's ability to map large bright regions quickly and in two transitions simultaneously allows researchers to analyse the varying conditions in star-forming regions comprehensively.We will show first results of FIFI-LS observations of M42 and M17. M42 with the Orion Bar, a well-known PDR seen edge-on was one of the very first objects observed with FIFI-LS. Subsequently, we have observed M42 in a growing number of transitions. We also have observed the PDR in M17 in several transitions. The PDRs are clearly identified by the complementary spatial extent of the ionized and neutral species. From the ratios of the [OI] (63 and 146µm) and [OIII] (52 and 88µm) line pairs, the [CII] (158µm) line and combinations thereof, physical conditions in the different phases and the transition regions can be derived. We are presenting preliminary results.

  5. 7 CFR 305.23 - Steam sterilization treatment schedules.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Steam sterilization treatment schedules. 305.23... HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE PHYTOSANITARY TREATMENTS Heat Treatments § 305.23 Steam sterilization treatment schedules. Treatment schedule Temperature( °F) Pressure Exposure period...

  6. Long-Term Monitoring of the High-Energy Gamma-Ray Emission from LS I +61 deg 303 and LS 5039

    NASA Technical Reports Server (NTRS)

    Hadasch, D.; Torres, D. F.; Tanaka, T.; Corbet, R. H. D.; Hill, A. B.; Dubois, R.; Dubus, G.; Glanzman, T.; Corbel, S.; Li, J.; hide

    2012-01-01

    The Fermi Large Area Telescope (LAT) reported the first definitive gigaelectron volts detections of the binaries LS I +61 deg 303 and LS 5039 in the first year after its launch in 2008 June. These detections were unambiguous as a consequence of the reduced positional uncertainty and the detection of modulated gamma-ray emission on the corresponding orbital periods. An analysis of new data from the LAT, comprising 30 months of observations, identifies a change in the gamma-ray behavior of LS I +61 deg 303. An increase in flux is detected in 2009 March and a steady decline in the orbital flux modulation is observed. Significant emission up to 30 gigaelectron volts is detected by the LAT; prior data sets led to upper limits only. Contemporaneous terraelectron volt observations no longer detected the source, or found it-in one orbit-close to periastron, far from the phases at which the source previously appeared at terraelectron volt energies. The detailed numerical simulations and models that exist within the literature do not predict or explain many of these features now observed at gigaelectron volt and terraelectron volt energies. New ideas and models are needed to fully explain and understand this behavior. A detailed phase-resolved analysis of the spectral characterization of LS I +61 deg 303 in the gigaelectron volt regime ascribes a power law with an exponential cutoff spectrum along each analyzed portion of the system's orbit. The on-source exposure of LS 5039 is also substantially increased with respect to our prior publication. In this case, whereas the general gamma-ray properties remain consistent, the increased statistics of the current data set allows for a deeper investigation of its orbital and spectral evolution.

  7. Long-Term Monitoring Of The High-Energy γ-Ray Emission From Ls I +61°303 And Ls 5039

    DOE PAGES

    Hadasch, D.; Torres, D. F.; Tanaka, T.; ...

    2012-03-22

    The Fermi Large Area Telescope (LAT) reported the first definitive GeV detections of the binaries LS I +61°303 and LS 5039 in the first year after its launch in 2008 June. These detections were unambiguous as a consequence of the reduced positional uncertainty and the detection of modulated γ-ray emission on the corresponding orbital periods. An analysis of new data from the LAT, comprising 30 months of observations, identifies a change in the γ-ray behavior of LS I +61°303. An increase in flux is detected in 2009 March and a steady decline in the orbital flux modulation is observed. Significantmore » emission up to 30 GeV is detected by the LAT; prior data sets led to upper limits only. Contemporaneous TeV observations no longer detected the source, or found it—in one orbit—close to periastron, far from the phases at which the source previously appeared at TeV energies. The detailed numerical simulations and models that exist within the literature do not predict or explain many of these features now observed at GeV and TeV energies. New ideas and models are needed to fully explain and understand this behavior. A detailed phase-resolved analysis of the spectral characterization of LS I +61°303 in the GeV regime ascribes a power law with an exponential cutoff spectrum along each analyzed portion of the system's orbit. The on-source exposure of LS 5039 is also substantially increased with respect to our prior publication. In this case, whereas the general γ-ray properties remain consistent, the increased statistics of the current data set allows for a deeper investigation of its orbital and spectral evolution.« less

  8. 7 CFR 355.23 - Recordkeeping, access, and reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Recordkeeping, access, and reports. 355.23 Section 355.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ENDANGERED SPECIES REGULATIONS CONCERNING TERRESTRIAL PLANTS...

  9. 7 CFR 355.23 - Recordkeeping, access, and reports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 5 2014-01-01 2014-01-01 false Recordkeeping, access, and reports. 355.23 Section 355.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ENDANGERED SPECIES REGULATIONS CONCERNING TERRESTRIAL PLANTS...

  10. 7 CFR 355.23 - Recordkeeping, access, and reports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 5 2011-01-01 2011-01-01 false Recordkeeping, access, and reports. 355.23 Section 355.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ENDANGERED SPECIES REGULATIONS CONCERNING TERRESTRIAL PLANTS...

  11. 7 CFR 355.23 - Recordkeeping, access, and reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 5 2013-01-01 2013-01-01 false Recordkeeping, access, and reports. 355.23 Section 355.23 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ENDANGERED SPECIES REGULATIONS CONCERNING TERRESTRIAL PLANTS...

  12. 32 CFR 1602.23 - State.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false State. 1602.23 Section 1602.23 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.23 State. The word State includes, where applicable, the several States of the United States, the City of New York...

  13. 23 CFR 669.7 - Certification requirement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ENFORCEMENT OF HEAVY VEHICLE USE TAX § 669.7 Certification requirement. The Governor of each state, or his or... payment of the heavy vehicle use tax as a condition of registration in accordance with 23 U.S.C. 141(d...

  14. LS Bound based gene selection for DNA microarray data.

    PubMed

    Zhou, Xin; Mao, K Z

    2005-04-15

    One problem with discriminant analysis of DNA microarray data is that each sample is represented by quite a large number of genes, and many of them are irrelevant, insignificant or redundant to the discriminant problem at hand. Methods for selecting important genes are, therefore, of much significance in microarray data analysis. In the present study, a new criterion, called LS Bound measure, is proposed to address the gene selection problem. The LS Bound measure is derived from leave-one-out procedure of LS-SVMs (least squares support vector machines), and as the upper bound for leave-one-out classification results it reflects to some extent the generalization performance of gene subsets. We applied this LS Bound measure for gene selection on two benchmark microarray datasets: colon cancer and leukemia. We also compared the LS Bound measure with other evaluation criteria, including the well-known Fisher's ratio and Mahalanobis class separability measure, and other published gene selection algorithms, including Weighting factor and SVM Recursive Feature Elimination. The strength of the LS Bound measure is that it provides gene subsets leading to more accurate classification results than the filter method while its computational complexity is at the level of the filter method. A companion website can be accessed at http://www.ntu.edu.sg/home5/pg02776030/lsbound/. The website contains: (1) the source code of the gene selection algorithm; (2) the complete set of tables and figures regarding the experimental study; (3) proof of the inequality (9). ekzmao@ntu.edu.sg.

  15. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (23rd, Tarrytown, New York, March 20-21, 2009)

    ERIC Educational Resources Information Center

    Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

    2009-01-01

    The document is a summary of the conference proceedings for the 23rd Annual Farmingdale State College Teaching of Psychology Conference held on March 20-21, 2009 at the DoubleTree Hotel in Tarrytown, New York. The conference featured a keynote address by Dr. Jeffrey Nevid on Reaching and teaching the millennials: Helping today's students become…

  16. 7 CFR 75.23 - Issuance of inspection certificate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Issuance of inspection certificate. 75.23 Section 75.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT...

  17. 7 CFR 75.23 - Issuance of inspection certificate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Issuance of inspection certificate. 75.23 Section 75.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT...

  18. 7 CFR 75.23 - Issuance of inspection certificate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Issuance of inspection certificate. 75.23 Section 75.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT...

  19. 7 CFR 75.23 - Issuance of inspection certificate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Issuance of inspection certificate. 75.23 Section 75.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT...

  20. 7 CFR 75.23 - Issuance of inspection certificate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Issuance of inspection certificate. 75.23 Section 75.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT...

  1. [Influence of ET-1 and ETA receptor blocker (BQ123) on the level of TNF-α in the brain rat].

    PubMed

    Gorąca, Anna; Skibska, Beata

    2016-06-01

    Endothelin 1 (ET-1) in addition to the vasoconstriction, also has mitogenic, proinflammatory and proagregation activities. The mediators of inflammatory responses are cytokines, including special role attributed to tumor necrosis factor (TNF-α). The aim of this study was to evaluate the effect of ET-1 and its receptor blocker (BQ123) on the level of TNF-α in the brain rat. Experiments were performed on four groups of Wistar-Kyoto rats. Animals were divided into four groups of 8 rats. Group I - control was administered into the tail vein solution of 0.9 % NaCl. Group II - saline followed by ET-1 (3 μg/kg b.w.). Group III - saline followed by BQ123 (1 mg/kg b.w.). Group IV (BQ123/ET-1) - BQ123 (1 mg/kg b.w.) administered 30 min before ET-1 (3 μg/kg b.w.). Administration of ET-1 at doses of 3 μg/kg b.w. resulted in a statistically significant increase in TNF-α concentrations in brain homogenates compared to the control group (p<0.01). Administration of the ET(A) receptor blocker - BQ123 (1mg/kg b.w.) 30 min before administration of ET-1 significantly decreased in TNF-α concentrations in brain homogenates (p <0.01). ET-1 is significantly increased in TNF-α levels in brain homogenates, while BQ123 given 30 min before administration of ET-1 caused a significant decrease in TNF-α levels, suggesting that its anti-inflammatory activity. © 2016 MEDPRESS.

  2. 7 CFR 1427.23 - Cotton loan deficiency payments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Cotton loan deficiency payments. 1427.23 Section 1427..., DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COTTON Nonrecourse Cotton Loan and Loan Deficiency Payments § 1427.23 Cotton loan deficiency payments. (a) In order to be eligible to receive such...

  3. 7 CFR 1427.23 - Cotton loan deficiency payments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Cotton loan deficiency payments. 1427.23 Section 1427..., DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COTTON Nonrecourse Cotton Loan and Loan Deficiency Payments § 1427.23 Cotton loan deficiency payments. (a) In order to be eligible to receive such...

  4. 7 CFR 1427.23 - Cotton loan deficiency payments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Cotton loan deficiency payments. 1427.23 Section 1427..., DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COTTON Nonrecourse Cotton Loan and Loan Deficiency Payments § 1427.23 Cotton loan deficiency payments. (a) In order to be eligible to receive such...

  5. 7 CFR 1427.23 - Cotton loan deficiency payments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Cotton loan deficiency payments. 1427.23 Section 1427..., DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COTTON Nonrecourse Cotton Loan and Loan Deficiency Payments § 1427.23 Cotton loan deficiency payments. (a) In order to be eligible to receive such...

  6. 7 CFR 1427.23 - Cotton loan deficiency payments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Cotton loan deficiency payments. 1427.23 Section 1427..., DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COTTON Nonrecourse Cotton Loan and Loan Deficiency Payments § 1427.23 Cotton loan deficiency payments. (a) In order to be eligible to receive such...

  7. 23 CFR 752.7 - Information centers and systems.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Information centers and systems. 752.7 Section 752.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT LANDSCAPE AND ROADSIDE DEVELOPMENT § 752.7 Information centers and systems. (a) The State may establish at...

  8. 23 CFR 752.7 - Information centers and systems.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Information centers and systems. 752.7 Section 752.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT LANDSCAPE AND ROADSIDE DEVELOPMENT § 752.7 Information centers and systems. (a) The State may establish at...

  9. 23 CFR 752.7 - Information centers and systems.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Information centers and systems. 752.7 Section 752.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT LANDSCAPE AND ROADSIDE DEVELOPMENT § 752.7 Information centers and systems. (a) The State may establish at...

  10. 23 CFR 752.7 - Information centers and systems.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Information centers and systems. 752.7 Section 752.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT LANDSCAPE AND ROADSIDE DEVELOPMENT § 752.7 Information centers and systems. (a) The State may establish at...

  11. 23 CFR 752.7 - Information centers and systems.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Information centers and systems. 752.7 Section 752.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT LANDSCAPE AND ROADSIDE DEVELOPMENT § 752.7 Information centers and systems. (a) The State may establish at...

  12. LONG-TERM MONITORING OF THE HIGH-ENERGY {gamma}-RAY EMISSION FROM LS I +61 Degree-Sign 303 AND LS 5039

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hadasch, D.; Torres, D. F.; Caliandro, G. A.

    2012-04-10

    The Fermi Large Area Telescope (LAT) reported the first definitive GeV detections of the binaries LS I +61 Degree-Sign 303 and LS 5039 in the first year after its launch in 2008 June. These detections were unambiguous as a consequence of the reduced positional uncertainty and the detection of modulated {gamma}-ray emission on the corresponding orbital periods. An analysis of new data from the LAT, comprising 30 months of observations, identifies a change in the {gamma}-ray behavior of LS I +61 Degree-Sign 303. An increase in flux is detected in 2009 March and a steady decline in the orbital fluxmore » modulation is observed. Significant emission up to 30 GeV is detected by the LAT; prior data sets led to upper limits only. Contemporaneous TeV observations no longer detected the source, or found it-in one orbit-close to periastron, far from the phases at which the source previously appeared at TeV energies. The detailed numerical simulations and models that exist within the literature do not predict or explain many of these features now observed at GeV and TeV energies. New ideas and models are needed to fully explain and understand this behavior. A detailed phase-resolved analysis of the spectral characterization of LS I +61 Degree-Sign 303 in the GeV regime ascribes a power law with an exponential cutoff spectrum along each analyzed portion of the system's orbit. The on-source exposure of LS 5039 is also substantially increased with respect to our prior publication. In this case, whereas the general {gamma}-ray properties remain consistent, the increased statistics of the current data set allows for a deeper investigation of its orbital and spectral evolution.« less

  13. Differential sensitivity of the nicotinic receptor of long (LS) and short (SS) sleep mice to ethanol (E) and forane (F)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McArdle, J.J.; Choi, J.J.

    1989-02-09

    Studies of inbred mice indicate that heredity determines the behavioral response to CNS depressants. For example, LS mice lose their righting reflex at blood levels of E having no effect on this reflex of SS mice. In order to determine if such differential sensitivity extends to the effects of depressants known to alter the mean open time (tau) of the ion channel activated by the nicotinic acetylcholine receptor (AR), we used an extracellular electrode to record miniature end-plate currents (23 C) from the triangularis sterni muscle of adult male LS and SS mice. The average decay time constant (tau) ofmore » 70 currents was calculated before, during and after drug exposure. Tau was the same for LS and SS mice (1.41 {plus minus} 0.03 mS and 1.47 {plus minus} 0.02 mS, respectively) prior to treatment and was reversible prolonged by E and shortened by F as expected. However, tau of SS mice was more responsive. For example, 25 mM of E increased tau by 12.9% and 3.8% in SS and LS mice, respectively. Likewise, the decrease of tau in response to 3 mM F was 18.5% and 9.2%. The net result was that the curve relating tau for LS mice to drug concentration was to the right of the for SS mice. These data suggest that the sensitivity of the peripheral AR to CNS depressants can be genetically controlled.« less

  14. Mars at Ls 121°

    NASA Image and Video Library

    2006-10-02

    These MOC images capture what Mars typically looks like in mid-afternoon at Ls 121°. In other words, with the exception of occasional differences in weather and polar frost patterns, this is what the red planet looks like this month October 2006

  15. 47 CFR 7.23 - Actions by the Commission on its own motion.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Actions by the Commission on its own motion. 7.23 Section 7.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO VOICEMAIL AND INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.23 Actions by the...

  16. 47 CFR 7.23 - Actions by the Commission on its own motion.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Actions by the Commission on its own motion. 7.23 Section 7.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO VOICEMAIL AND INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.23 Actions by the...

  17. 47 CFR 7.23 - Actions by the Commission on its own motion.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Actions by the Commission on its own motion. 7.23 Section 7.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO VOICEMAIL AND INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.23 Actions by the...

  18. 7 CFR 318.13-23 - Cut flowers from Hawaii.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 5 2011-01-01 2011-01-01 false Cut flowers from Hawaii. 318.13-23 Section 318.13-23... From Hawaii and the Territories § 318.13-23 Cut flowers from Hawaii. (a) Except for cut blooms and leis... paragraph (b) of this section, cut flowers may be moved interstate from Hawaii under limited permit, to a...

  19. 7 CFR 318.13-23 - Cut flowers from Hawaii.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Cut flowers from Hawaii. 318.13-23 Section 318.13-23... From Hawaii and the Territories § 318.13-23 Cut flowers from Hawaii. (a) Except for cut blooms and leis... paragraph (b) of this section, cut flowers may be moved interstate from Hawaii under limited permit, to a...

  20. 7 CFR 318.13-23 - Cut flowers from Hawaii.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 5 2013-01-01 2013-01-01 false Cut flowers from Hawaii. 318.13-23 Section 318.13-23... From Hawaii and the Territories § 318.13-23 Cut flowers from Hawaii. (a) Except for cut blooms and leis... paragraph (b) of this section, cut flowers may be moved interstate from Hawaii under limited permit, to a...

  1. 7 CFR 318.13-23 - Cut flowers from Hawaii.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Cut flowers from Hawaii. 318.13-23 Section 318.13-23... From Hawaii and the Territories § 318.13-23 Cut flowers from Hawaii. (a) Except for cut blooms and leis... paragraph (b) of this section, cut flowers may be moved interstate from Hawaii under limited permit, to a...

  2. 7 CFR 318.13-23 - Cut flowers from Hawaii.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 5 2014-01-01 2014-01-01 false Cut flowers from Hawaii. 318.13-23 Section 318.13-23... From Hawaii and the Territories § 318.13-23 Cut flowers from Hawaii. (a) Except for cut blooms and leis... paragraph (b) of this section, cut flowers may be moved interstate from Hawaii under limited permit, to a...

  3. Semisupervised learning using Bayesian interpretation: application to LS-SVM.

    PubMed

    Adankon, Mathias M; Cheriet, Mohamed; Biem, Alain

    2011-04-01

    Bayesian reasoning provides an ideal basis for representing and manipulating uncertain knowledge, with the result that many interesting algorithms in machine learning are based on Bayesian inference. In this paper, we use the Bayesian approach with one and two levels of inference to model the semisupervised learning problem and give its application to the successful kernel classifier support vector machine (SVM) and its variant least-squares SVM (LS-SVM). Taking advantage of Bayesian interpretation of LS-SVM, we develop a semisupervised learning algorithm for Bayesian LS-SVM using our approach based on two levels of inference. Experimental results on both artificial and real pattern recognition problems show the utility of our method.

  4. 23 CFR 200.7 - FHWA Title VI policy.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

  5. 23 CFR 200.7 - FHWA Title VI policy.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

  6. 23 CFR 200.7 - FHWA Title VI policy.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

  7. 23 CFR 200.7 - FHWA Title VI policy.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

  8. Revitalising Mathematics Classroom Teaching through Lesson Study (LS): A Malaysian Case Study

    ERIC Educational Resources Information Center

    Lim, Chap Sam; Kor, Liew Kee; Chia, Hui Min

    2016-01-01

    This paper discusses how implementation of Lesson Study (LS) has brought about evolving changes in the quality of mathematics classroom teaching in one Chinese primary school. The Japanese model of LS was adapted as a teacher professional development to improve mathematics teachers' teaching practices. The LS group consisted of five mathematics…

  9. A modified JPEG-LS lossless compression method for remote sensing images

    NASA Astrophysics Data System (ADS)

    Deng, Lihua; Huang, Zhenghua

    2015-12-01

    As many variable length source coders, JPEG-LS is highly vulnerable to channel errors which occur in the transmission of remote sensing images. The error diffusion is one of the important factors which infect its robustness. The common method of improving the error resilience of JPEG-LS is dividing the image into many strips or blocks, and then coding each of them independently, but this method reduces the coding efficiency. In this paper, a block based JPEP-LS lossless compression method with an adaptive parameter is proposed. In the modified scheme, the threshold parameter RESET is adapted to an image and the compression efficiency is close to that of the conventional JPEG-LS.

  10. Biodegradation test of SPS-LS blends as polymer electrolyte membrane fuel cells

    NASA Astrophysics Data System (ADS)

    Putri, Zufira; Arcana, I. Made

    2014-03-01

    Sulfonated polystyrene (SPS) can be applied as a proton exchange membrane fuel cell due to its fairly good chemical stability. In order to be applied as polymer electrolyte membrane fuel cells (PEMFCs), membrane polymer should have a good ionic conductivity, high proton conductivity, and high mechanical strength. Lignosulfonate (LS) is a complex biopolymer which has crosslinks and sulfonate groups. SPS-LS blends with addition of SiO2 are used to increase the proton conductivity and to improve the mechanical properties and thermal stability. However, the biodegradation test of SPS-LS blends is required to determine whether the application of these membranes to be applied as an environmentally friendly membrane. In this study, had been done the synthesis of SPS, biodegradability test of SPS-LS blends with variations of LS and SiO2 compositions. The biodegradation test was carried out in solid medium of Luria Bertani (LB) with an activated sludge used as a source of microorganism at incubation temperature of 37°C. Based on the results obtained indicated that SPS-LS-SiO2 blends are more decomposed by microorganism than SPS-LS blends. This result is supported by analysis of weight reduction percentage, functional groups with Fourier Transform Infrared (FTIR) Spectroscopy, and morphological surface with Scanning Electron Microscopy (SEM).

  11. 23 CFR 656.7 - Determination of an exception.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Determination of an exception. 656.7 Section 656.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS... and services include: public service announcements, computer services, and project-related staff time...

  12. 23 CFR 656.7 - Determination of an exception.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Determination of an exception. 656.7 Section 656.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS... and services include: public service announcements, computer services, and project-related staff time...

  13. 23 CFR 656.7 - Determination of an exception.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Determination of an exception. 656.7 Section 656.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS... and services include: public service announcements, computer services, and project-related staff time...

  14. 23 CFR 656.7 - Determination of an exception.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Determination of an exception. 656.7 Section 656.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS... and services include: public service announcements, computer services, and project-related staff time...

  15. 23 CFR 656.7 - Determination of an exception.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Determination of an exception. 656.7 Section 656.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS... and services include: public service announcements, computer services, and project-related staff time...

  16. BQ-123 prevents LPS-induced preterm birth in mice via the induction of uterine and placental IL-10.

    PubMed

    Olgun, Nicole S; Hanna, Nazeeh; Reznik, Sandra E

    2015-02-01

    Preterm birth (PTB), defined as any delivery occurring prior to the completion of 37 weeks' gestation, currently accounts for 11-12% of all births in the United States. Maternal genito-urinary infections account for up to 40% of all PTBS and induce a pro-inflammatory state in the host. The potent vasoconstrictor Endothelin-1 (ET-1) is known to be upregulated in the setting of infection, and elicits its effect by binding to the ETA receptor. We have previously shown that antagonism of the ETA receptor with BQ-123 is capable of preventing LPS-induced PTB in mice. We hypothesize that the administration of BQ-123 post LPS exposure will dismantle a positive feedback loop observed with pro-inflammatory cytokines upstream of ET-1. On GD 15.5, pregnant C57BL/6 mice were injected with PBS, LPS, BQ-123, or LPS+BQ-123. Changes at both the level of transcription and translation were observed in uterus and placenta in the ET-1 axis and in pro- and anti-inflammatory cytokines over the course of 12h. We discovered that BQ-123, when administered 10h post LPS, is capable of increasing production of uterine and placental Interleukin-10, causing a shift away from the pro-inflammatory state. We also observed that antagonism of the ETA receptor decreased IL-1β and TNFα in the placenta while also decreasing transcription of ET-1 in the uterus. Our results reinforce the role of ET-1 at the maternal fetal interface and highlight the potential benefit of ETA receptor blockade via the suppression of ET-1, and induction of a Th2 cytokine dominant state. Copyright © 2014. Published by Elsevier Inc.

  17. 7 CFR 3406.23 - Access to peer review information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Access to peer review information. 3406.23 Section 3406.23 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE 1890 INSTITUTION CAPACITY BUILDING GRANTS...

  18. Biodegradation test of SPS-LS blends as polymer electrolyte membrane fuel cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Putri, Zufira, E-mail: zufira.putri@gmail.com, E-mail: arcana@chem.itb.ac.id; Arcana, I Made, E-mail: zufira.putri@gmail.com, E-mail: arcana@chem.itb.ac.id

    Sulfonated polystyrene (SPS) can be applied as a proton exchange membrane fuel cell due to its fairly good chemical stability. In order to be applied as polymer electrolyte membrane fuel cells (PEMFCs), membrane polymer should have a good ionic conductivity, high proton conductivity, and high mechanical strength. Lignosulfonate (LS) is a complex biopolymer which has crosslinks and sulfonate groups. SPS-LS blends with addition of SiO{sub 2} are used to increase the proton conductivity and to improve the mechanical properties and thermal stability. However, the biodegradation test of SPS-LS blends is required to determine whether the application of these membranes tomore » be applied as an environmentally friendly membrane. In this study, had been done the synthesis of SPS, biodegradability test of SPS-LS blends with variations of LS and SiO{sub 2} compositions. The biodegradation test was carried out in solid medium of Luria Bertani (LB) with an activated sludge used as a source of microorganism at incubation temperature of 37°C. Based on the results obtained indicated that SPS-LS-SiO{sub 2} blends are more decomposed by microorganism than SPS-LS blends. This result is supported by analysis of weight reduction percentage, functional groups with Fourier Transform Infrared (FTIR) Spectroscopy, and morphological surface with Scanning Electron Microscopy (SEM)« less

  19. Quantitative (23) Na MRI of human knee cartilage using dual-tuned (1) H/(23) Na transceiver array radiofrequency coil at 7 tesla.

    PubMed

    Moon, Chan Hong; Kim, Jung-Hwan; Zhao, Tiejun; Bae, Kyongtae Ty

    2013-11-01

    To develop quantitative dual-tuned (DT) (1) H/(23) Na MRI of human knee cartilage in vivo at 7 Tesla (T). A sensitive (23) Na transceiver array RF coil was developed at 7T. B1 fields generated by the transceiver array coil were characterized and corrected in the (23) Na images. Point spread function (PSF) of the (23) Na images was measured, and the signal decrease due to partial-volume-effect was compensated in [(23) Na] quantification of knee cartilage. SNR and [(23) Na] in anterior femoral cartilage were measured from seven healthy subjects. SNR of (23) Na image with the transceiver array coil was higher than that of birdcage coil. SNR in the cartilage at 2-mm isotropic resolution was 26.80 ± 3.69 (n = 7). B1 transmission and reception fields produced by the DT coil at 7T were similar to each other. Effective full-width-half-maximum of (23) Na image was ∼5 mm at 2-mm resolution. Mean [(23) Na] was 288.13 ± 29.50 mM (n = 7) in the anterior femoral cartilage of normal subjects. We developed a new high-sensitivity (23) Na RF coil for knee MRI at 7T. Our (1) H/(23) Na MRI allowed quantitative measurement of [(23) Na] in knee cartilage by measuring PSF and cartilage thickness from (23) Na and (1) H image, respectively. Copyright © 2013 Wiley Periodicals, Inc.

  20. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

  1. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

  2. 7 CFR 23.4 - State Rural Development Advisory Council.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Development Advisory Council will insure that programs proposed under title V including regional programs... 7 Agriculture 1 2010-01-01 2010-01-01 false State Rural Development Advisory Council. 23.4 Section 23.4 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK State...

  3. 6 CFR 7.23 - Emergency release of classified information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ....23 Section 7.23 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CLASSIFIED...) The Secretary of Homeland Security has delegated to certain DHS employees the authority to disclose... emergency situations when there is an imminent threat to life or in defense of the homeland. (b) In...

  4. 7 CFR 1.23 - Records in formal adjudication proceedings.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Records in formal adjudication proceedings. 1.23 Section 1.23 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official... Agriculture, Washington, DC 20250, and shall be made available to the public. [65 FR 46341, July 28, 2000] ...

  5. 7 CFR 201.23 - Name of shipper or consignee.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Name of shipper or consignee. 201.23 Section 201.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Labeling Agricultura...

  6. 7 CFR 201.23 - Name of shipper or consignee.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Name of shipper or consignee. 201.23 Section 201.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Labeling Agricultura...

  7. 7 CFR 201.23 - Name of shipper or consignee.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Name of shipper or consignee. 201.23 Section 201.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Labeling Agricultura...

  8. 7 CFR 201.23 - Name of shipper or consignee.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Name of shipper or consignee. 201.23 Section 201.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Labeling Agricultura...

  9. 7 CFR 201.23 - Name of shipper or consignee.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Name of shipper or consignee. 201.23 Section 201.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Labeling Agricultura...

  10. Spectroscopic Classification of SN 2018bq (=ASASSN-18ac) as a Type Ia Supernova

    NASA Astrophysics Data System (ADS)

    Lin, Han; Xiang, Danfeng; Rui, Liming; Wang, Xiaofeng; Xiao, Feng; Ren, Juanjuan; Zhang, Tianmeng; Zhang, Jujia

    2018-01-01

    We obtained an optical spectrum (range 510-860 nm) of SN 2018bq(=ASASSN-18ac), discovered by All Sky Automated Survey for Supernova(ASAS-SN), on UT 09.81 2018 with the 2.16-m telescope (+BFOSC) at Xinglong Station of National Astronomical Observatories of China (NAOC).

  11. 7 CFR 1730.23 - Review rating summary, RUS Form 300.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Review rating summary, RUS Form 300. 1730.23 Section 1730.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE... § 1730.23 Review rating summary, RUS Form 300. RUS Form 300 in Appendix A shall be used when required by...

  12. Regional-scale calculation of the LS factor using parallel processing

    NASA Astrophysics Data System (ADS)

    Liu, Kai; Tang, Guoan; Jiang, Ling; Zhu, A.-Xing; Yang, Jianyi; Song, Xiaodong

    2015-05-01

    With the increase of data resolution and the increasing application of USLE over large areas, the existing serial implementation of algorithms for computing the LS factor is becoming a bottleneck. In this paper, a parallel processing model based on message passing interface (MPI) is presented for the calculation of the LS factor, so that massive datasets at a regional scale can be processed efficiently. The parallel model contains algorithms for calculating flow direction, flow accumulation, drainage network, slope, slope length and the LS factor. According to the existence of data dependence, the algorithms are divided into local algorithms and global algorithms. Parallel strategy are designed according to the algorithm characters including the decomposition method for maintaining the integrity of the results, optimized workflow for reducing the time taken for exporting the unnecessary intermediate data and a buffer-communication-computation strategy for improving the communication efficiency. Experiments on a multi-node system show that the proposed parallel model allows efficient calculation of the LS factor at a regional scale with a massive dataset.

  13. Effects of doping on ferroelectric properties and leakage current behavior of KNN-LT-LS thin films on SrTiO3 substrate

    NASA Astrophysics Data System (ADS)

    Abazari, M.; Safari, A.

    2009-05-01

    We report the effects of Ba, Ti, and Mn dopants on ferroelectric polarization and leakage current of (K0.44Na0.52Li0.04)(Nb0.84Ta0.1Sb0.06)O3 (KNN-LT-LS) thin films deposited by pulsed laser deposition. It is shown that donor dopants such as Ba2+, which increased the resistivity in bulk KNN-LT-LS, had an opposite effect in the thin film. Ti4+ as an acceptor B-site dopant reduces the leakage current by an order of magnitude, while the polarization values showed a slight degradation. Mn4+, however, was found to effectively suppress the leakage current by over two orders of magnitude while enhancing the polarization, with 15 and 23 μC/cm2 remanent and saturated polarization, whose values are ˜70% and 82% of the reported values for bulk composition. This phenomenon has been associated with the dual effect of Mn4+ in KNN-LT-LS thin film, by substituting both A- and B-site cations. A detailed description on how each dopant affects the concentrations of vacancies in the lattice is presented. Mn-doped KNN-LT-LS thin films are shown to be a promising candidate for lead-free thin films and applications.

  14. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the...

  15. BQ-123 prevents LPS-induced preterm birth in mice via the induction of uterine and placental IL-10

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olgun, Nicole S., E-mail: Nicole.olgun02@stjohns.edu; Women and Children's Research Laboratory, Winthrop University Hospital, 259 1st Street, Mineola, NY, 11501; Hanna, Nazeeh, E-mail: Nhanna@winthrop.org

    Preterm birth (PTB), defined as any delivery occurring prior to the completion of 37 weeks' gestation, currently accounts for 11–12% of all births in the United States. Maternal genito-urinary infections account for up to 40% of all PTBS and induce a pro-inflammatory state in the host. The potent vasoconstrictor Endothelin-1 (ET-1) is known to be upregulated in the setting of infection, and elicits its effect by binding to the ET{sub A} receptor. We have previously shown that antagonism of the ET{sub A} receptor with BQ-123 is capable of preventing LPS-induced PTB in mice. We hypothesize that the administration of BQ-123more » post LPS exposure will dismantle a positive feedback loop observed with pro-inflammatory cytokines upstream of ET-1. On GD 15.5, pregnant C57BL/6 mice were injected with PBS, LPS, BQ-123, or LPS + BQ-123. Changes at both the level of transcription and translation were observed in uterus and placenta in the ET-1 axis and in pro- and anti-inflammatory cytokines over the course of 12 h. We discovered that BQ-123, when administered 10 h post LPS, is capable of increasing production of uterine and placental Interleukin-10, causing a shift away from the pro-inflammatory state. We also observed that antagonism of the ET{sub A} receptor decreased IL-1β and TNFα in the placenta while also decreasing transcription of ET-1 in the uterus. Our results reinforce the role of ET-1 at the maternal fetal interface and highlight the potential benefit of ET{sub A} receptor blockade via the suppression of ET-1, and induction of a Th2 cytokine dominant state. - Highlights: • The pro-inflammatory response to LPS in the uterus and placenta is ET-1 dependent. • ET{sub A} blockade triggers up-regulation of IL-10 in uterus and placenta. • A positive feedback loop drives ET-1 expression in gestational tissue.« less

  16. Membrane transport mechanisms of choline in human intestinal epithelial LS180 cells.

    PubMed

    Horie, Asuka; Ishida, Kazuya; Watanabe, Yuri; Shibata, Kaito; Hashimoto, Yukiya

    2014-12-01

    The aim of the present study was to investigate the membrane transport mechanisms of choline using human intestinal epithelial LS180 cells. The mRNA of choline transporter-like proteins (CTLs) was expressed significantly in LS180 cells, and the rank order was CTL1 > CTL4 > CTL3 > CTL2 > CTL5. In contrast, the mRNA expression of other choline transporters, organic cation transporter (OCT) 1, OCT2 and high-affinity choline transporter 1 (CHT1), was considerably lower in LS180 cells. Five mm unlabelled choline, hemicolinium-3 and guanidine, but not tetraethylammonium, inhibited the cellular uptake of 100 µm choline in LS180 cells. The uptake of choline into LS180 cells was virtually Na(+)-independent. The uptake of choline was significantly decreased by acidification of the extracellular pH; however, it was not increased by alkalization of the extracellular pH. In addition, both acidification and alkalization of intracellular pH decreased the uptake of choline, indicating that the choline uptake in LS180 cells is not stimulated by the outward H(+) gradient. On the other hand, the uptake of choline was decreased by membrane depolarization along with increasing extracellular K(+) concentration. In addition, the Na(+)-independent uptake of choline was saturable, and the Km value was estimated to be 108 µm. These findings suggest that the uptake of choline into LS180 cells is membrane potential-dependent, but not outward H(+) gradient-dependent. Copyright © 2014 John Wiley & Sons, Ltd.

  17. AGO Austria recommendation on screening and diagnosis of Lynch syndrome (LS).

    PubMed

    Zeimet, Alain G; Mori, Harald; Petru, Edgar; Polterauer, Stephan; Reinthaller, Alexander; Schauer, Christian; Scholl-Firon, Tonja; Singer, Christian; Wimmer, Katharina; Zschocke, Johannes; Marth, Christian

    2017-07-01

    This manuscript reports the consensus recommendations on screening and diagnosis of Lynch syndrome (LS) in patients with endometrial or ovarian cancer as well as on possible preventive measures in effectively LS-diagnosed women. The recommendations are issued by the Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) of the Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG) after consultation of the most recent and relevant literature and following deliberation by the Genetic Task-Force convoked May, 2015 by the AGO Council. The Austrian AGO recommends immunohistochemical tissue screening for type-I and type-II endometrial cancers in all patients below the age of 70 years, and for all endometrioid and clear-cell ovarian cancers independently of the patient's age. If needed immunohistochemistry should be complemented by tissue MLH1 promotor hypermethylation testing and/or microsatellite instability (MSI) analysis. The diagnosis LS requires confirmation through identification of a germline mutation by a molecular genetic examination in the mismatch repair genes using the patient's blood. This should be performed without preceding tissue screening when in LS-associated cancer patients the family history fulfills the Amsterdam II or the revised Bethesda criteria. In LS-diagnosed women, the age for prophylactic surgery should be set flexibly based on an informed consent. Regarding the monitoring of these women, chemo-preventive measures as well as screening procedures either to avoid or to early detect LS-related tumors are discussed with a special light on their specific limitations.

  18. Wilms' tumor in New York State: epidemiology and survivorship.

    PubMed

    Griffel, M

    1977-12-01

    The outcomes during the period 1950--1972 were compared for Wilms' tumor patients in Erie County, New York (Buffalo and environs) and in a random selection of 23 counties having much smaller populations. For the Erie cohorts of 1967 to 1972 an 87 per cent 7-year survival rate was found as compared with a 50 per cent survival for the corresponding cohorts of the less populous couties. For the years 1960--1966 the 5-year survival rates were respectively 67 and 25 per cent and for the decade 1950--1959, 26 and 23 per cent. The principal conclusion is that within the last 15 years the Erie residents have fared better than residents of the smaller counties. The difference is attributed to the better treatment and care available at some of the hospitals in Buffalo. Data on incidence, age at diagnosis, male/female ratio, and laterality are presented.

  19. 7 CFR 1794.23 - Proposals normally requiring an EA.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Proposals normally requiring an EA. 1794.23 Section... § 1794.23 Proposals normally requiring an EA. RUS will normally prepare an EA for all proposed actions... require an EA and shall be subject to the requirements of §§ 1794.40 through 1794.44. (a) General...

  20. 7 CFR 1794.23 - Proposals normally requiring an EA.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Proposals normally requiring an EA. 1794.23 Section... § 1794.23 Proposals normally requiring an EA. RUS will normally prepare an EA for all proposed actions... require an EA and shall be subject to the requirements of §§ 1794.40 through 1794.44. (a) General...

  1. 7 CFR 1794.23 - Proposals normally requiring an EA.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Proposals normally requiring an EA. 1794.23 Section... § 1794.23 Proposals normally requiring an EA. RUS will normally prepare an EA for all proposed actions... require an EA and shall be subject to the requirements of §§ 1794.40 through 1794.44. (a) General...

  2. Effect of Lactobacillus salivarius Ls-33 on fecal microbiota in obese adolescents.

    PubMed

    Larsen, Nadja; Vogensen, Finn K; Gøbel, Rikke Juul; Michaelsen, Kim F; Forssten, Sofia D; Lahtinen, Sampo J; Jakobsen, Mogens

    2013-12-01

    This study is a part of the clinical trials with probiotic bacterium Lactobacillus salivarius Ls-33 conducted in obese adolescents. Previously reported clinical studies showed no effect of Ls-33 consumption on the metabolic syndrome in the subject group. The aim of the study was to investigate the impact of L. salivarius Ls-33 on fecal microbiota in obese adolescents. The study was a double-blinded intervention with 50 subjects randomized to intake of L. salivarius Ls-33 or placebo for 12 weeks. The fecal microbiota was assessed by real-time quantitative PCR before and after intervention. Concentrations of fecal short chain fatty acids were determined using gas chromatography. Ratios of Bacteroides-Prevotella-Porphyromonas group to Firmicutes belonging bacteria, including Clostridium cluster XIV, Blautia coccoides_Eubacteria rectale group and Roseburia intestinalis, were significantly increased (p ≤ 0.05) after administration of Ls-33. The cell numbers of fecal bacteria, including the groups above as well as Clostridium cluster I, Clostridium cluster IV, Faecalibacterium prausnitzii, Enterobacteriaceae, Enterococcus, the Lactobacillus group and Bifidobacterium were not significantly altered by intervention. Similarly, short chain fatty acids remained unaffected. L. salivarius Ls-33 might modify the fecal microbiota in obese adolescents in a way not related to metabolic syndrome. NCT 01020617. Copyright © 2013 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

  3. LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures.

    PubMed

    Ryan, Michael; Diekhans, Mark; Lien, Stephanie; Liu, Yun; Karchin, Rachel

    2009-06-01

    LS-SNP/PDB is a new WWW resource for genome-wide annotation of human non-synonymous (amino acid changing) SNPs. It serves high-quality protein graphics rendered with UCSF Chimera molecular visualization software. The system is kept up-to-date by an automated, high-throughput build pipeline that systematically maps human nsSNPs onto Protein Data Bank structures and annotates several biologically relevant features. LS-SNP/PDB is available at (http://ls-snp.icm.jhu.edu/ls-snp-pdb) and via links from protein data bank (PDB) biology and chemistry tabs, UCSC Genome Browser Gene Details and SNP Details pages and PharmGKB Gene Variants Downloads/Cross-References pages.

  4. Solving Fuzzy Optimization Problem Using Hybrid Ls-Sa Method

    NASA Astrophysics Data System (ADS)

    Vasant, Pandian

    2011-06-01

    Fuzzy optimization problem has been one of the most and prominent topics inside the broad area of computational intelligent. It's especially relevant in the filed of fuzzy non-linear programming. It's application as well as practical realization can been seen in all the real world problems. In this paper a large scale non-linear fuzzy programming problem has been solved by hybrid optimization techniques of Line Search (LS), Simulated Annealing (SA) and Pattern Search (PS). As industrial production planning problem with cubic objective function, 8 decision variables and 29 constraints has been solved successfully using LS-SA-PS hybrid optimization techniques. The computational results for the objective function respect to vagueness factor and level of satisfaction has been provided in the form of 2D and 3D plots. The outcome is very promising and strongly suggests that the hybrid LS-SA-PS algorithm is very efficient and productive in solving the large scale non-linear fuzzy programming problem.

  5. 7 CFR 1778.23 - Grant closing and disbursement of funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Grant closing and disbursement of funds. 1778.23 Section 1778.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS...

  6. Regionalized equations for bankfull-discharge and channel characteristics of streams in New York State—Hydrologic Region 7 in western New York

    USGS Publications Warehouse

    Mulvihill, Christiane I.; Ernst, Anne G.; Baldigo, Barry P.

    2006-01-01

    Computation of bankfull discharge and channel dimensions (width, depth, and cross-sectional area) at ungaged sites requires equations that relate bankfull discharge and channel dimensions to drainage-area at gaged sites. Bankfull-channel information commonly is needed for watershed assessments, stream channel classification, and the design of stream-restoration projects. Such equations are most accurate if they are derived on the basis of data from streams within a region of uniform hydrologic, climatic, and physiographic conditions and applied only within that region. New York State contains eight hydrologic regions that were previously delineated on the basis of high-flow (flood) characteristics. This report presents drainage areas and associated bankfull characteristics (discharge and channel dimensions) for surveyed streams in western New York (Region 7).Stream-survey data and discharge records from seven active and three inactive USGS streamflow-gaging stations were used in regression analyses to relate drainage area to bankfull discharge and to bankfull channel width, depth, and cross-sectional area. The resulting equations are:(1) bankfull discharge, in cubic feet per second = 37.1*(drainage area, in square miles)0.765;(2) bankfull channel width, in feet = 10.8*(drainage area, in square miles)0.458;(3) bankfull channel depth, in feet = 1.47*(drainage area, in square miles)0.199; and(4) bankfull channel cross-sectional area, in square feet = 15.9*(drainage area, in square mile)0.656.The coefficients of determination (R2) for these four equations were 0.94, 0.89, 0.52, and 0.96, respectively. The high coefficients of determination for three of these equations (discharge, width, and cross-sectional area) indicate that much of the range in the variables was explained by the drainage area. The low coefficient of determination for the equation relating bankfull depth to drainage area, however, suggests that other factors also affected water depth. Recurrence

  7. 7 CFR 4280.23 - Requirements for lending from Revolving Loan Fund.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Requirements for lending from Revolving Loan Fund. 4280.23 Section 4280.23 Agriculture Regulations of the Department of Agriculture (Continued) RURAL... Economic Development Loan and Grant Programs § 4280.23 Requirements for lending from Revolving Loan Fund...

  8. Spectral and Temporal Characteristics of LS PEG and TW PIC Using XMM-NEWTON Data

    NASA Astrophysics Data System (ADS)

    Talebpour Sheshvan, Nasrin; Balman, Solen

    2016-07-01

    We report the analysis of archival XMM-Newton X-ray observations of LS Peg and TW Pic. These are Cataclysmic Variables (CVs) suggested as Intermediate Polars (IPs), but unconfirmed in the X-rays. Identification of several periodic oscillations in the optical band hint them as IPs. Unlike the previous spectral analysis on the EPIC-MOS data by fitting a hot optically thin plasma emission model with a single temperature for LS Peg, we simultaneously fitted all EPIC spectrum (pn+MOS) using a composite model of absorption for interstellar medium (tbabs) with two different partial covering absorbers (pcfabs) including a multitemperature plasma emission component (cevmkl) and a Gaussian emission line at 6.4 keV. TW Pic is best modeled in a similar manner with only one partial covering absorber and an extra Gaussian emission line at 6.7 keV. LS Peg has a maximum plasma temperature of ˜14.8 keV with an X-ray luminosity of ˜5×10^{32}ergs ^{-1} translating to an accretion rate of ˜1.27×10^{-10}M _{⊙}yr ^{-1}. TW Pic shows kT _{max} ˜38.7 keV with an X-ray luminosity around 1.6×10^{33}ergs ^{-1} at an accretion rate of ˜4×10^{-10}M _{⊙}yr ^{-1}. In addition, we discuss orbital modulations in the X-rays and power spectral analysis, and derive the EPIC pn spectra for orbital minimum and orbital maximum phases for both sources. We elaborate on the geometry of accretion and absorption in the X-ray emitting regions of both sources with articulation on the magnetic nature.

  9. 76 FR 253 - Airworthiness Directives; ROLLADEN-SCHNEIDER Flugzeugbau GmbH Model LS6 Gliders

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ... Airworthiness Directives; ROLLADEN-SCHNEIDER Flugzeugbau GmbH Model LS6 Gliders AGENCY: Federal Aviation... condition does not exist in the Model LS6-c gliders. FAA's Determination We are issuing this AD rescission... Model LS6 glider, and the unsafe condition described previously is not likely to exist or develop in the...

  10. Experimental Study of the Effects of EIPA, Losartan, and BQ-123 on Electrophysiological Changes Induced by Myocardial Stretch.

    PubMed

    Chorro, Francisco J; Canto, Irene Del; Brines, Laia; Such-Miquel, Luis; Calvo, Conrado; Soler, Carlos; Zarzoso, Manuel; Trapero, Isabel; Tormos, Álvaro; Such, Luis

    2015-12-01

    Mechanical response to myocardial stretch has been explained by various mechanisms, which include Na(+)/H(+) exchanger activation by autocrine-paracrine system activity. Drug-induced changes were analyzed to investigate the role of these mechanisms in the electrophysiological responses to acute myocardial stretch. Multiple epicardial electrodes and mapping techniques were used to analyze changes in ventricular fibrillation induced by acute myocardial stretch in isolated perfused rabbit hearts. Four series were studied: control (n = 9); during perfusion with the angiotensin receptor blocker losartan (1 μM, n = 8); during perfusion with the endothelin A receptor blocker BQ-123 (0.1 μM, n = 9), and during perfusion with the Na(+)/H(+) exchanger inhibitor EIPA (5-[N-ethyl-N-isopropyl]-amiloride) (1 μM, n = 9). EIPA attenuated the increase in the dominant frequency of stretch-induced fibrillation (control=40.4%; losartan=36% [not significant]; BQ-123=46% [not significant]; and EIPA=22% [P<.001]). During stretch, the activation maps were less complex (P<.0001) and the spectral concentration of the arrhythmia was greater (greater regularity) in the EIPA series: control=18 (3%); EIPA = 26 (9%) (P < .02); losartan=18 (5%) (not significant); and BQ-123=18 (4%) (not significant). The Na(+)/H(+) exchanger inhibitor EIPA attenuated the electrophysiological effects responsible for the acceleration and increased complexity of ventricular fibrillation induced by acute myocardial stretch. The angiotensin II receptor antagonist losartan and the endothelin A receptor blocker BQ-123 did not modify these effects. Copyright © 2014 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  11. 6 CFR 7.23 - Emergency release of classified information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Emergency release of classified information. 7... NATIONAL SECURITY INFORMATION Classified Information § 7.23 Emergency release of classified information. (a... notify the DHS Chief Security Officer and the originating agency of the information disclosed. A copy of...

  12. 7α-Hydroxycholesterol Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells.

    PubMed

    Seo, Hyun Chul; Kim, Sun-Mi; Eo, Seong-Kug; Rhim, Byung-Yong; Kim, Koanhoi

    2015-01-01

    We investigated the question of whether 7-oxygenated cholesterol derivatives could affect inflammatory and/or immune responses in atherosclerosis by examining their effects on expression of IL-23 in monocytic cells. 7α-Hydroxycholesterol (7αOHChol) induced transcription of the TLR6 gene and elevated the level of cell surface TLR6 protein in THP-1 monocytic cells. Addition of an agonist of TLR6, FSL-1, to TLR6-expressing cells by treatment with 7αOHChol resulted in enhanced production of IL-23 and transcription of genes encoding the IL-23 subunit α (p19) and the IL-12 subunit β (p40). However, treatment with 7-ketocholesterol (7K) and 7β-hydroxycholesterol (7βOHChol) did not affect TLR6 expression, and addition of FSL-1 to cells treated with either 7K or 7βOHChol did not influence transcription of the genes. Pharmacological inhibition of ERK, Akt, or PI3K resulted in attenuated transcription of TLR6 induced by 7αOHChol as well as secretion of IL-23 enhanced by 7αOHChol plus FSL-1. Inhibition of p38 MAPK or JNK resulted in attenuated secretion of IL-23. These results indicate that a certain type of 7-oxygenated cholesterol like 7αOHChol can elicit TLR6-mediated expression of IL-23 by monocytic cells via PI3K/Akt and MAPKs pathways.

  13. 7α-Hydroxycholesterol Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells

    PubMed Central

    Seo, Hyun Chul; Kim, Sun-Mi; Eo, Seong-Kug; Rhim, Byung-Yong; Kim, Koanhoi

    2015-01-01

    We investigated the question of whether 7-oxygenated cholesterol derivatives could affect inflammatory and/or immune responses in atherosclerosis by examining their effects on expression of IL-23 in monocytic cells. 7α-Hydroxycholesterol (7αOHChol) induced transcription of the TLR6 gene and elevated the level of cell surface TLR6 protein in THP-1 monocytic cells. Addition of an agonist of TLR6, FSL-1, to TLR6-expressing cells by treatment with 7αOHChol resulted in enhanced production of IL-23 and transcription of genes encoding the IL-23 subunit α (p19) and the IL-12 subunit β (p40). However, treatment with 7-ketocholesterol (7K) and 7β-hydroxycholesterol (7βOHChol) did not affect TLR6 expression, and addition of FSL-1 to cells treated with either 7K or 7βOHChol did not influence transcription of the genes. Pharmacological inhibition of ERK, Akt, or PI3K resulted in attenuated transcription of TLR6 induced by 7αOHChol as well as secretion of IL-23 enhanced by 7αOHChol plus FSL-1. Inhibition of p38 MAPK or JNK resulted in attenuated secretion of IL-23. These results indicate that a certain type of 7-oxygenated cholesterol like 7αOHChol can elicit TLR6-mediated expression of IL-23 by monocytic cells via PI3K/Akt and MAPKs pathways. PMID:25593648

  14. 23 CFR 192.7 - Apportionment of withheld funds after compliance.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Apportionment of withheld funds after compliance. 192.7 Section 192.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES DRUG OFFENDER'S DRIVER'S LICENSE SUSPENSION § 192.7 Apportionment of withheld funds after compliance...

  15. 23 CFR 192.7 - Apportionment of withheld funds after compliance.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Apportionment of withheld funds after compliance. 192.7 Section 192.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES DRUG OFFENDER'S DRIVER'S LICENSE SUSPENSION § 192.7 Apportionment of withheld funds after compliance...

  16. 23 CFR 192.7 - Apportionment of withheld funds after compliance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Apportionment of withheld funds after compliance. 192.7 Section 192.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES DRUG OFFENDER'S DRIVER'S LICENSE SUSPENSION § 192.7 Apportionment of withheld funds after compliance...

  17. 23 CFR 192.7 - Apportionment of withheld funds after compliance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Apportionment of withheld funds after compliance. 192.7 Section 192.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES DRUG OFFENDER'S DRIVER'S LICENSE SUSPENSION § 192.7 Apportionment of withheld funds after compliance...

  18. Improved Detection of Winter Lightning in the Tohoku Region of Japan using Vaisala’s LS700x Technology

    NASA Astrophysics Data System (ADS)

    Cummins, Kenneth L.; Honma, Noriyasu; Pifer, Alburt E.; Rogers, Tim; Tatsumi, Masataka

    The demand for both data quality and the range of Cloud-to-Ground (CG) lightning parameters is highest for forensic applications within the electric utility industry. For years, the research and operational communities within this industry in Japan have pointed out a limitation of these LLS networks in the detection and location of damaging (high-current and/or large charge transfer) lightning flashes during the winter months (so-called “Winter Lightning”). Most of these flashes appear to be upward-connecting discharges, frequently referred to as “Ground-to-Cloud” (GC) flashes. The basic architecture and design of Vaisala’s new LS700x lightning sensor was developed in-part to improve detection of these unusual and complex flashes. This paper presents our progress-to-date on this effort. We include a review of the winter lightning detection problem, an overview of the LS700x architecture, a discussion of how this architecture was exploited to evaluate and improve performance for winter lightning, and a presentation of results-to-date on performance improvement. A comparison of GC detection performance between Tohoku’s operational 9-sensor IMPACT (ALDF 141-T) LLS and its 6-sensor LS700x research network indicates roughly a factor-of-two improvement for this class of discharges, with an overall detection of 23/24 (96%) of GC flashes.

  19. A threshold-based fixed predictor for JPEG-LS image compression

    NASA Astrophysics Data System (ADS)

    Deng, Lihua; Huang, Zhenghua; Yao, Shoukui

    2018-03-01

    In JPEG-LS, fixed predictor based on median edge detector (MED) only detect horizontal and vertical edges, and thus produces large prediction errors in the locality of diagonal edges. In this paper, we propose a threshold-based edge detection scheme for the fixed predictor. The proposed scheme can detect not only the horizontal and vertical edges, but also diagonal edges. For some certain thresholds, the proposed scheme can be simplified to other existing schemes. So, it can also be regarded as the integration of these existing schemes. For a suitable threshold, the accuracy of horizontal and vertical edges detection is higher than the existing median edge detection in JPEG-LS. Thus, the proposed fixed predictor outperforms the existing JPEG-LS predictors for all images tested, while the complexity of the overall algorithm is maintained at a similar level.

  20. RAB-7 Antagonizes LET-23 EGFR Signaling during Vulva Development in Caenorhabditis elegans

    PubMed Central

    Skorobogata, Olga; Rocheleau, Christian E.

    2012-01-01

    The Rab7 GTPase regulates late endosome trafficking of the Epidermal Growth Factor Receptor (EGFR) to the lysosome for degradation. However, less is known about how Rab7 activity, functioning late in the endocytic pathway, affects EGFR signaling. Here we used Caenorhabditis elegans vulva cell fate induction, a paradigm for genetic analysis of EGFR/Receptor Tyrosine Kinase (RTK) signaling, to assess the genetic requirements for rab-7. Using a rab-7 deletion mutant, we demonstrate that rab-7 antagonizes LET-23 EGFR signaling to a similar extent, but in a distinct manner, as previously described negative regulators such as sli-1 c-Cbl. Epistasis analysis places rab-7 upstream of or in parallel to lin-3 EGF and let-23 EGFR. However, expression of gfp::rab-7 in the Vulva Presursor Cells (VPCs) is sufficient to rescue the rab-7(−) VPC induction phenotypes indicating that RAB-7 functions in the signal receiving cell. We show that components of the Endosomal Sorting Complex Required for Transport (ESCRT)-0, and -I, complexes, hgrs-1 Hrs, and vps-28, also antagonize signaling, suggesting that LET-23 EGFR likely transits through Multivesicular Bodies (MVBs) en route to the lysosome. Consistent with RAB-7 regulating LET-23 EGFR trafficking, rab-7 mutants have increased number of LET-23::GFP-positive endosomes. Our data imply that Rab7, by mediating EGFR trafficking and degradation, plays an important role in downregulation of EGFR signaling. Failure to downregulate EGFR signaling contributes to oncogenesis, and thus Rab7 could possess tumor suppressor activity in humans. PMID:22558469

  1. RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans.

    PubMed

    Skorobogata, Olga; Rocheleau, Christian E

    2012-01-01

    The Rab7 GTPase regulates late endosome trafficking of the Epidermal Growth Factor Receptor (EGFR) to the lysosome for degradation. However, less is known about how Rab7 activity, functioning late in the endocytic pathway, affects EGFR signaling. Here we used Caenorhabditis elegans vulva cell fate induction, a paradigm for genetic analysis of EGFR/Receptor Tyrosine Kinase (RTK) signaling, to assess the genetic requirements for rab-7. Using a rab-7 deletion mutant, we demonstrate that rab-7 antagonizes LET-23 EGFR signaling to a similar extent, but in a distinct manner, as previously described negative regulators such as sli-1 c-Cbl. Epistasis analysis places rab-7 upstream of or in parallel to lin-3 EGF and let-23 EGFR. However, expression of gfp::rab-7 in the Vulva Presursor Cells (VPCs) is sufficient to rescue the rab-7(-) VPC induction phenotypes indicating that RAB-7 functions in the signal receiving cell. We show that components of the Endosomal Sorting Complex Required for Transport (ESCRT)-0, and -I, complexes, hgrs-1 Hrs, and vps-28, also antagonize signaling, suggesting that LET-23 EGFR likely transits through Multivesicular Bodies (MVBs) en route to the lysosome. Consistent with RAB-7 regulating LET-23 EGFR trafficking, rab-7 mutants have increased number of LET-23::GFP-positive endosomes. Our data imply that Rab7, by mediating EGFR trafficking and degradation, plays an important role in downregulation of EGFR signaling. Failure to downregulate EGFR signaling contributes to oncogenesis, and thus Rab7 could possess tumor suppressor activity in humans.

  2. A Modified LS+AR Model to Improve the Accuracy of the Short-term Polar Motion Prediction

    NASA Astrophysics Data System (ADS)

    Wang, Z. W.; Wang, Q. X.; Ding, Y. Q.; Zhang, J. J.; Liu, S. S.

    2017-03-01

    There are two problems of the LS (Least Squares)+AR (AutoRegressive) model in polar motion forecast: the inner residual value of LS fitting is reasonable, but the residual value of LS extrapolation is poor; and the LS fitting residual sequence is non-linear. It is unsuitable to establish an AR model for the residual sequence to be forecasted, based on the residual sequence before forecast epoch. In this paper, we make solution to those two problems with two steps. First, restrictions are added to the two endpoints of LS fitting data to fix them on the LS fitting curve. Therefore, the fitting values next to the two endpoints are very close to the observation values. Secondly, we select the interpolation residual sequence of an inward LS fitting curve, which has a similar variation trend as the LS extrapolation residual sequence, as the modeling object of AR for the residual forecast. Calculation examples show that this solution can effectively improve the short-term polar motion prediction accuracy by the LS+AR model. In addition, the comparison results of the forecast models of RLS (Robustified Least Squares)+AR, RLS+ARIMA (AutoRegressive Integrated Moving Average), and LS+ANN (Artificial Neural Network) confirm the feasibility and effectiveness of the solution for the polar motion forecast. The results, especially for the polar motion forecast in the 1-10 days, show that the forecast accuracy of the proposed model can reach the world level.

  3. 7 CFR 27.23 - Duplicate sets of samples of cotton.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Duplicate sets of samples of cotton. 27.23 Section 27... REGULATIONS COTTON CLASSIFICATION UNDER COTTON FUTURES LEGISLATION Regulations Inspection and Samples § 27.23 Duplicate sets of samples of cotton. The duplicate sets of samples shall be inclosed in wrappers or...

  4. 7 CFR 27.23 - Duplicate sets of samples of cotton.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Duplicate sets of samples of cotton. 27.23 Section 27... REGULATIONS COTTON CLASSIFICATION UNDER COTTON FUTURES LEGISLATION Regulations Inspection and Samples § 27.23 Duplicate sets of samples of cotton. The duplicate sets of samples shall be inclosed in wrappers or...

  5. 7 CFR 27.23 - Duplicate sets of samples of cotton.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Duplicate sets of samples of cotton. 27.23 Section 27... REGULATIONS COTTON CLASSIFICATION UNDER COTTON FUTURES LEGISLATION Regulations Inspection and Samples § 27.23 Duplicate sets of samples of cotton. The duplicate sets of samples shall be inclosed in wrappers or...

  6. 7 CFR 27.23 - Duplicate sets of samples of cotton.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Duplicate sets of samples of cotton. 27.23 Section 27... REGULATIONS COTTON CLASSIFICATION UNDER COTTON FUTURES LEGISLATION Regulations Inspection and Samples § 27.23 Duplicate sets of samples of cotton. The duplicate sets of samples shall be inclosed in wrappers or...

  7. 7 CFR 27.23 - Duplicate sets of samples of cotton.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Duplicate sets of samples of cotton. 27.23 Section 27... REGULATIONS COTTON CLASSIFICATION UNDER COTTON FUTURES LEGISLATION Regulations Inspection and Samples § 27.23 Duplicate sets of samples of cotton. The duplicate sets of samples shall be inclosed in wrappers or...

  8. West Nile virus outbreak among horses in New York State, 1999 and 2000.

    PubMed Central

    Trock, S. C.; Meade, B. J.; Glaser, A. L.; Ostlund, E. N.; Lanciotti, R. S.; Cropp, B. C.; Kulasekera, V.; Kramer, L. D.; Komar, N.

    2001-01-01

    West Nile (WN) virus was identified in the Western Hemisphere in 1999. Along with human encephalitis cases, 20 equine cases of WN virus were detected in 1999 and 23 equine cases in 2000 in New York. During both years, the equine cases occurred after human cases in New York had been identified. PMID:11585543

  9. 23 CFR 1235.7 - Parking space design, construction, and designation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Parking space design, construction, and designation. 1235.7 Section 1235.7 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES UNIFORM SYSTEM FOR PARKING FOR PERSONS WITH DISABILITIES § 1235.7 Parking space design,...

  10. New York, New York

    ERIC Educational Resources Information Center

    Santos, Thomas W.

    2008-01-01

    This article describes New York City. It presents information about its history, immigration process, geography, architecture, rivers, bridges, famous buildings and parks, famous neighborhoods, arts and entertainment, and tourist attractions and activities. The article also provides useful websites about New York City. It ends with a text about…

  11. Lamb Wave Damage Quantification Using GA-Based LS-SVM.

    PubMed

    Sun, Fuqiang; Wang, Ning; He, Jingjing; Guan, Xuefei; Yang, Jinsong

    2017-06-12

    Lamb waves have been reported to be an efficient tool for non-destructive evaluations (NDE) for various application scenarios. However, accurate and reliable damage quantification using the Lamb wave method is still a practical challenge, due to the complex underlying mechanism of Lamb wave propagation and damage detection. This paper presents a Lamb wave damage quantification method using a least square support vector machine (LS-SVM) and a genetic algorithm (GA). Three damage sensitive features, namely, normalized amplitude, phase change, and correlation coefficient, were proposed to describe changes of Lamb wave characteristics caused by damage. In view of commonly used data-driven methods, the GA-based LS-SVM model using the proposed three damage sensitive features was implemented to evaluate the crack size. The GA method was adopted to optimize the model parameters. The results of GA-based LS-SVM were validated using coupon test data and lap joint component test data with naturally developed fatigue cracks. Cases of different loading and manufacturer were also included to further verify the robustness of the proposed method for crack quantification.

  12. Lamb Wave Damage Quantification Using GA-Based LS-SVM

    PubMed Central

    Sun, Fuqiang; Wang, Ning; He, Jingjing; Guan, Xuefei; Yang, Jinsong

    2017-01-01

    Lamb waves have been reported to be an efficient tool for non-destructive evaluations (NDE) for various application scenarios. However, accurate and reliable damage quantification using the Lamb wave method is still a practical challenge, due to the complex underlying mechanism of Lamb wave propagation and damage detection. This paper presents a Lamb wave damage quantification method using a least square support vector machine (LS-SVM) and a genetic algorithm (GA). Three damage sensitive features, namely, normalized amplitude, phase change, and correlation coefficient, were proposed to describe changes of Lamb wave characteristics caused by damage. In view of commonly used data-driven methods, the GA-based LS-SVM model using the proposed three damage sensitive features was implemented to evaluate the crack size. The GA method was adopted to optimize the model parameters. The results of GA-based LS-SVM were validated using coupon test data and lap joint component test data with naturally developed fatigue cracks. Cases of different loading and manufacturer were also included to further verify the robustness of the proposed method for crack quantification. PMID:28773003

  13. 7 CFR 1412.23 - Base acres and Conservation Reserve Program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Base acres and Conservation Reserve Program. 1412.23... Base Acres for a Farm for Covered Commodities § 1412.23 Base acres and Conservation Reserve Program. (a... year, adjust the base acres for covered commodities and peanuts with respect to the farm by the number...

  14. 7 CFR 1412.23 - Base acres and Conservation Reserve Program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Base acres and Conservation Reserve Program. 1412.23... Base Acres for a Farm for Covered Commodities § 1412.23 Base acres and Conservation Reserve Program. (a... year, adjust the base acres for covered commodities and peanuts with respect to the farm by the number...

  15. 7 CFR 1412.23 - Base acres and Conservation Reserve Program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Base acres and Conservation Reserve Program. 1412.23... Base Acres for a Farm for Covered Commodities § 1412.23 Base acres and Conservation Reserve Program. (a... year, adjust the base acres for covered commodities and peanuts with respect to the farm by the number...

  16. The amino acid sequence of Staphylococcus aureus penicillinase.

    PubMed Central

    Ambler, R P

    1975-01-01

    The amino acid sequence of the penicillinase (penicillin amido-beta-lactamhydrolase, EC 3.5.2.6) from Staphylococcus aureus strain PC1 was determined. The protein consists of a single polypeptide chain of 257 residues, and the sequence was determined by characterization of tryptic, chymotryptic, peptic and CNBr peptides, with some additional evidence from thermolysin and S. aureus proteinase peptides. A mistake in the preliminary report of the sequence is corrected; residues 113-116 are now thought to be -Lys-Lys-Val-Lys- rather than -Lys-Val-Lys-Lys-. Detailed evidence for the amino acid sequence has been deposited as Supplementary Publication SUP 50056 (91 pages) at the British Library (Lending Division), Boston Spa, Wetherby, West Yorkshire LS23 7BQ, U.K., from whom copies may be obtained on the terms given in Biochem. J. (1975) 145, 5. PMID:1218078

  17. pLS010 plasmid vector

    DOEpatents

    Lacks, Sanford A.; Balganesh, Tanjore S.

    1988-01-01

    Disclosed is recombinant plasmid pLS101, consisting essentially of a 2.0 Kb malM gene fragment ligated to a 4.4 Kb T.sub.c r DNA fragment, which is particularly useful for transforming Gram-positive bacteria. This plasmid contains at least four restriction sites suitable for inserting exogeneous gene sequences. Also disclosed is a method for plasmid isolation by penicillin selection, as well as processes for enrichment of recombinant plasmids in Gram-positive bacterial systems.

  18. [Measurement of soil organic matter and available K based on SPA-LS-SVM].

    PubMed

    Zhang, Hai-Liang; Liu, Xue-Mei; He, Yong

    2014-05-01

    Visible and short wave infrared spectroscopy (Vis/SW-NIRS) was investigated in the present study for measurement of soil organic matter (OM) and available potassium (K). Four types of pretreatments including smoothing, SNV, MSC and SG smoothing+first derivative were adopted to eliminate the system noises and external disturbances. Then partial least squares regression (PLSR) and least squares-support vector machine (LS-SVM) models were implemented for calibration models. The LS-SVM model was built by using characteristic wavelength based on successive projections algorithm (SPA). Simultaneously, the performance of LSSVM models was compared with PLSR models. The results indicated that LS-SVM models using characteristic wavelength as inputs based on SPA outperformed PLSR models. The optimal SPA-LS-SVM models were achieved, and the correlation coefficient (r), and RMSEP were 0. 860 2 and 2. 98 for OM and 0. 730 5 and 15. 78 for K, respectively. The results indicated that visible and short wave near infrared spectroscopy (Vis/SW-NIRS) (325 approximately 1 075 nm) combined with LS-SVM based on SPA could be utilized as a precision method for the determination of soil properties.

  19. Photophysical, photochemical and BSA binding/BQ quenching properties of quaternizable coumarin containing water soluble zinc phthalocyanine complexes

    NASA Astrophysics Data System (ADS)

    Esenpınar, Aliye Aslı; Durmuş, Mahmut; Bulut, Mustafa

    2011-08-01

    The non-peripherally ( np-QZnPc) and peripherally ( p-QZnPc) tetrakis-[7-oxo-(3-[(2-diethylaminomethyliodide)ethyl)]-4-methylcoumarin]-phthalocyaninatozinc complexes have been prepared by quaternization of non-peripherally and peripherally tetrakis[7-oxo-(3-[(2-diethylamino)ethyl)]-methylcoumarin] phthalocyaninato zinc complexes with methyliodide in dimethylsulfoxide (DMSO). The new quaternized zinc phthalocyanine complex ( np-QZnPc) has been characterized by elementel analysis, MALDI-TOF, IR and UV-vis spectral data. The photophysical and photochemical properties of the peripherally and non-peripherally quaternized tetrakis-3-[(2-diethylamino)ethyl]-7-oxo-4-methylcoumarin substituted zinc phthalocyanines are reported. The effects of the position of the substituents and the aggregation of the phthalocyanine molecules on the photophysical and photochemical properties are also investigated. General trends are described for photodegradation, singlet oxygen and fluorescence quantum yields, and fluorescence lifetimes for complexes np-ZnPc/ p-ZnPc in DMSO and for complexes np-QZnPc/p-QZnPc in DMSO, phosphate buffered solution (PBS) and PBS+Triton-X 100 solutions. The fluorescence of the tetra-substituted quaternized zinc phthalocyanine complexes ( np-QZnPc/ p-QZnPc) are effectively quenched addition of 1,4-benzoquinone (BQ) and this study also presented the ionic zinc phthalocyanine complexes strongly bind to bovine serum albumin (BSA).

  20. pLS101 plasmid vector

    DOEpatents

    Lacks, S.A.; Balganesh, T.S.

    1985-02-19

    Disclosed is recombinant plasmid pLS101, consisting essentially of a 2.0 Kb ma1M gene fragment ligated to a 4.4 Kb Tcr DNA fragment, which is particularly useful for transforming Gram-positive bacteria. This plasmid contains at least four restriction sites suitable for inserting exogeneous gene sequences. Also disclosed is a method for plasmid isolation by penicillin selection, as well as processes for enrichment of recombinant plasmids in Gram-positive bacterial systems. 5 figs., 2 tabs.

  1. Genome features of Pseudomonas putida LS46, a novel polyhydroxyalkanoate producer and its comparison with other P. putida strains

    PubMed Central

    2014-01-01

    A novel strain of Pseudomonas putida LS46 was isolated from wastewater on the basis of its ability to synthesize medium chain-length polyhydroxyalkanoates (mcl-PHAs). P.putida LS46 was differentiated from other P.putida strains on the basis of cpn60 (UT). The complete genome of P.putida LS46 was sequenced and annotated. Its chromosome is 5,86,2556 bp in size with GC ratio of 61.69. It is encoding 5316 genes, including 7 rRNA genes and 76 tRNA genes. Nucleotide sequence data of the complete P. putida LS46 genome was compared with nine other P. putida strains (KT2440, F1, BIRD-1, S16, ND6, DOT-T1E, UW4, W619 and GB-1) identified either as biocontrol agents or as bioremediation agents and isolated from different geographical region and different environment. BLASTn analysis of whole genome sequences of the ten P. putida strains revealed nucleotide sequence identities of 86.54 to 97.52%. P.putida genome arrangement was LS46 highly similar to P.putida BIRD1 and P.putida ND6 but was markedly different than P.putida DOT-T1E, P.putida UW4 and P.putida W619. Fatty acid biosynthesis (fab), fatty acid degradation (fad) and PHA synthesis genes were highly conserved among biocontrol and bioremediation P.putida strains. Six genes in pha operon of P. putida LS46 showed >98% homology at gene and proteins level. It appears that polyhydroxyalkanoate (PHA) synthesis is an intrinsic property of P. putida and was not affected by its geographic origin. However, all strains, including P. putida LS46, were different from one another on the basis of house keeping genes, and presence of plasmid, prophages, insertion sequence elements and genomic islands. While P. putida LS46 was not selected for plant growth promotion or bioremediation capacity, its genome also encoded genes for root colonization, pyoverdine synthesis, oxidative stress (present in other soil isolates), degradation of aromatic compounds, heavy metal resistance and nicotinic acid degradation, manganese (Mn II) oxidation

  2. Comparative therapeutic efficacy of rhenium-188 radiolabeled-liposome and 5-fluorouracil in LS-174T human colon carcinoma solid tumor xenografts.

    PubMed

    Hsu, Chin-Wei; Chang, Ya-Jen; Chang, Chih-Hsien; Chen, Liang-Cheng; Lan, Keng-Li; Ting, Gann; Lee, Te-Wei

    2012-10-01

    Nanoliposomes are important carriers capable of packaging drugs for various delivery applications. Rhenium-188-radiolabeled liposome ((188)Re-liposome) has potential for radiotherapy and diagnostic imaging. To evaluate the targeting of (188)Re-liposome, biodistribution, microSPECT/CT, whole-body autoradiography (WBAR), and pharmacokinetics were performed in LS-174T human tumor-bearing mice. The comparative therapeutic efficacy of (188)Re-liposome and 5-fluorouracil (5-FU) was assessed according to inhibition of tumor growth and the survival ratio. The highest uptake of (188)Re-liposome in LS-174T tumor was found at 24 hours by biodistribution and microSPECT/CT imaging, showing a positive correlation for tumor targeting of (188)Re-liposome using the Pearson's correlation analysis (r=0.997). Pharmacokinetics of (188)Re-liposome showed the properties of high circulation time and high bioavailability (mean residence time [MRT]=18.8 hours, area under the curve [AUC]=1371%ID/g·h). For therapeutic efficacy, the tumor-bearing mice treated with (188)Re-liposome (80% maximum tolerated dose [MTD], 23.7 MBq) showed better tumor growth inhibition and longer survival time than those treated with 5-FU (80% MTD, 144 mg/kg). The median survival time for mice treated with (188)Re-liposome (58.5 days; p<0.05) was significantly better than those of 5-FU (48.25 days; p>0.05) and normal saline-treated mice (43.63 days). Dosimetry study revealed that the (188)Re-liposome did not lead to high absorbed doses in normal tissue, but did in small tumors. These results of imaging and biodistribution indicated the highly specific accumulation of tumor after intravenous (i.v.) injection of (188)Re-liposome. The therapeutic efficacy of radiotherapeutics of (188)Re-liposome have been confirmed in a LS-174T solid tumor animal model, which points to the potential benefit and promise of passive nanoliposome delivered radiotherapeutics for cancer treatment.

  3. 15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Notice to Department of Commerce organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the Secretary of Commerce USE OF PENALTY MAIL IN THE LOCATION AND RECOVERY OF MISSING CHILDREN § 23.7 Notice to...

  4. 15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Notice to Department of Commerce organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the Secretary of Commerce USE OF PENALTY MAIL IN THE LOCATION AND RECOVERY OF MISSING CHILDREN § 23.7 Notice to...

  5. 15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Notice to Department of Commerce organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the Secretary of Commerce USE OF PENALTY MAIL IN THE LOCATION AND RECOVERY OF MISSING CHILDREN § 23.7 Notice to...

  6. Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults

    PubMed Central

    Houser, Katherine V.; Yamshchikov, Galina; Saunders, Jamie G.; Holman, LaSonji A.; Gordon, Ingelise; Plummer, Sarah; Hendel, Cynthia S.; Conan-Cibotti, Michelle; Lorenzo, Margarita Gomez; Sitar, Sandra; Carlton, Kevin; Bailer, Robert T.; Narpala, Sandeep; McDermott, Adrian B.; Namboodiri, Aryan M.; Schwartz, Richard M.; Koup, Richard A.; Graham, Barney S.; Ledgerwood, Julie E.

    2018-01-01

    Background VRC01 is a human broadly neutralizing monoclonal antibody (bnMAb) against the CD4-binding site of the HIV-1 envelope glycoprotein (Env) that is currently being evaluated in a Phase IIb adult HIV-1 prevention efficacy trial. VRC01LS is a modified version of VRC01, designed for extended serum half-life by increased binding affinity to the neonatal Fc receptor. Methods and findings This Phase I dose-escalation study of VRC01LS in HIV-negative healthy adults was conducted by the Vaccine Research Center (VRC) at the National Institutes of Health (NIH) Clinical Center (Bethesda, MD). The age range of the study volunteers was 21–50 years; 51% of study volunteers were male and 49% were female. Primary objectives were safety and tolerability of VRC01LS intravenous (IV) infusions at 5, 20, and 40 mg/kg infused once, 20 mg/kg given three times at 12-week intervals, and subcutaneous (SC) delivery at 5 mg/kg delivered once, or three times at 12-week intervals. Secondary objectives were pharmacokinetics (PK), serum neutralization activity, and development of antidrug antibodies. Enrollment began on November 16, 2015, and concluded on August 23, 2017. This report describes the safety data for the first 37 volunteers who received administrations of VRC01LS. There were no serious adverse events (SAEs) or dose-limiting toxicities. Mild malaise and myalgia were the most common adverse events (AEs). There were six AEs assessed as possibly related to VRC01LS administration, and all were mild in severity and resolved during the study. PK data were modeled based on the first dose of VRC01LS in the first 25 volunteers to complete their schedule of evaluations. The mean (±SD) serum concentration 12 weeks after one IV administration of 20 mg/kg or 40 mg/kg were 180 ± 43 μg/mL (n = 7) and 326 ± 35 μg/mL (n = 5), respectively. The mean (±SD) serum concentration 12 weeks after one IV and SC administration of 5 mg/kg were 40 ± 3 μg/mL (n = 2) and 25 ± 5 μg/mL (n = 9

  7. The Ne3LS Network, Québec's initiative to evaluate the impact and promote a responsible and sustainable development of nanotechnology

    NASA Astrophysics Data System (ADS)

    Endo, Charles-Anica; Emond, Claude; Battista, Renaldo; Parizeau, Marie-Hélène; Beaudry, Catherine

    2011-07-01

    The spectacular progress made by nanosciences and nanotechnologies elicits as much hope and fear. Consequently, a great number of research and training initiatives on the ethical, environmental, economic, legal and social issues regarding nanotechnology development (Ne3LS) are emerging worldwide. In Québec, Canada, a Task Force was mandated by NanoQuébec to conceive a Ne3LS research and training strategy to assess those issues. This Task Force brought together experts from universities, governments or industry working in nanosciences and nanotechnologies or in Ne3LS. Their resulting action plan, made public in November 2006, contained several recommendations, including the creation of a knowledge network (Ne3LS Network). In the following years, after consulting with numerous key players concerned with the possible impacts of nanosciences and nanotechnologies in Québec, the Ne3LS Network was launched in January 2010 in partnership with the Fonds québécois de la recherche sur la nature et les technologies, the Fonds québécois de la recherche sur la société et la culture and the Fonds de la recherche en santé du Québec, NanoQuébec, the Institut de recherche Robert-Sauvé en santé et en sécurité du travail as well as the University of Montreal. Its objectives are to 1) Foster the development of Ne3LS research activities (grants and fellowships); 2) Spearhead the Canadian and international Ne3LS network; 3) Take part in the training of researchers and experts; 4) Encourage the creation of interactive tools for the general public; 5) Facilitate collaboration between decision-makers and experts; 6) Involve the scientific community through a host of activities (symposium, conferences, thematic events); 7) Build multidisciplinary research teams to evaluate the impact of nanotechnology.

  8. Follow That Satellite: EO-1 Maneuvers Into Close Formation With Landsat-7

    NASA Technical Reports Server (NTRS)

    DeFazio, Robert L.; Owens, Skip; Good, Susan; Bauer, Frank H. (Technical Monitor)

    2001-01-01

    As the Landsat-7 (LS-7) spacecraft continued NASA's historic program of earth imaging begun over three decades ago, NASA launched the Earth Observing-1 (EO-1) spacecraft carrying examples of the next generation of LS instruments. The validation method for these instruments was to have EO-1 fly in a close formation behind LS-7 on the same World Reference System (WRS) path. From that formation hundreds of near-coincident images would be taken by each spacecraft and compared to evaluate improvements in the EO-1 instruments. This paper will address the mission analysis required to launch and maneuver EO-1 into the formation with LS-7 where instrument validation was to occur plus a summary of completing the formation acquisition. Each EO-1 launch opportunity that occurred on a different day of a LS-7 16-day repeat cycle required a separate and distinct maneuver profile.

  9. Temporal Trends in Anesthesia-related Adverse Events in Cesarean Deliveries, New York State, 2003-2012.

    PubMed

    Guglielminotti, Jean; Wong, Cynthia A; Landau, Ruth; Li, Guohua

    2015-11-01

    Cesarean delivery (CD) is associated with significantly increased risks of anesthesia-related adverse events (ARAEs) and nonanesthetic perioperative morbidity compared with vaginal delivery. Temporal trends in these adverse outcomes remain unknown despite efforts to improve maternal safety. This study examines temporal trends in ARAEs and nonanesthetic perioperative complications in CDs in New York hospitals. Data are from the State Inpatient Database for New York, 2003-2012. ARAEs, including minor and major ARAEs, and nonanesthetic perioperative complications were identified through International Classification of Diseases, Ninth Revision, Clinical Modification codes. Statistical significance in time trends was assessed using the Cochran-Armitage test and multivariable logistic regression. Of the 785,854 CDs studied, 5,715 (730 per 100,000; 95% CI, 710 to 750) had at least one ARAE and 7,040 had at least one perioperative complication (890 per 100,000; 95% CI, 870 to 920). The overall annual rate of ARAEs decreased from 890 per 100,000 in 2003 to 660 in 2012 (25% decrease; 95% CI, 16 to 34; P < 0.0001). The rate of minor ARAEs decreased 23% (95% CI, 13 to 32) and of major ARAEs decreased 43% (95% CI, 23 to 63). No decrease was observed in the rate of ARAEs for CDs performed under general anesthesia. The rate of nonanesthetic complications increased 47% (95% CI, 31 to 63; P < 0.0001). Anesthesia-related outcomes in cesarean deliveries appear to have improved significantly across hospitals in New York in the past decade. Perioperative nonanesthetic complications remain a serious healthcare issue.

  10. 7 CFR 1218.23 - U.S. Highbush Blueberry Council.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false U.S. Highbush Blueberry Council. 1218.23 Section 1218... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions...

  11. 7 CFR 1218.23 - U.S. Highbush Blueberry Council.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false U.S. Highbush Blueberry Council. 1218.23 Section 1218... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions...

  12. 7 CFR 1218.23 - U.S. Highbush Blueberry Council.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false U.S. Highbush Blueberry Council. 1218.23 Section 1218... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions...

  13. 7 CFR 1218.23 - U.S. Highbush Blueberry Council.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false U.S. Highbush Blueberry Council. 1218.23 Section 1218... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions...

  14. 7 CFR 1218.23 - U.S. Highbush Blueberry Council.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false U.S. Highbush Blueberry Council. 1218.23 Section 1218... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions...

  15. 7 CFR 1470.23 - Conservation activity operation and maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Conservation activity operation and maintenance. 1470... STEWARDSHIP PROGRAM Contracts and Payments § 1470.23 Conservation activity operation and maintenance. The participant will maintain and manage existing conservation activities on the agricultural operation to at...

  16. 7 CFR 1470.23 - Conservation activity operation and maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Conservation activity operation and maintenance. 1470... STEWARDSHIP PROGRAM Contracts and Payments § 1470.23 Conservation activity operation and maintenance. The participant will operate and maintain existing conservation activities on the agricultural operation to at...

  17. Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin

    PubMed Central

    2012-01-01

    Background Influenza A virus non-structural protein 1 (NS1) is a virulence factor, which is targeted into the cell cytoplasm, nucleus and nucleolus. NS1 is a multi-functional protein that inhibits host cell pre-mRNA processing and counteracts host cell antiviral responses. Previously, we have shown that the NS1 protein of the H3N2 subtype influenza viruses possesses a C-terminal nuclear localization signal (NLS) that also functions as a nucleolar localization signal (NoLS) and targets the protein into the nucleolus. Results Here, we show that the NS1 protein of the human H3N2 virus subtype interacts in vitro primarily via its C-terminal NLS2/NoLS and to a minor extent via its N-terminal NLS1 with the nucleolar proteins, nucleolin and fibrillarin. Using chimeric green fluorescence protein (GFP)-NS1 fusion constructs, we show that the nucleolar retention of the NS1 protein is determined by its C-terminal NLS2/NoLS in vivo. Confocal laser microscopy analysis shows that the NS1 protein colocalizes with nucleolin in nucleoplasm and nucleolus and with B23 and fibrillarin in the nucleolus of influenza A/Udorn/72 virus-infected A549 cells. Since some viral proteins contain NoLSs, it is likely that viruses have evolved specific nucleolar functions. Conclusion NS1 protein of the human H3N2 virus interacts primarily via the C-terminal NLS2/NoLS and to a minor extent via the N-terminal NLS1 with the main nucleolar proteins, nucleolin, B23 and fibrillarin. PMID:22909121

  18. 7. Historic American Buildings Survey, Martin Linsey, Photographer March 23, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey, Martin Linsey, Photographer March 23, 1966 PHOTOCOPY OF ARCHITECT'S RENDERING FOR ROMANESQUE DESIGN. - Trinity Episcopal Church, Euclid Avenue & East Twenty-Second Street, Cleveland, Cuyahoga County, OH

  19. Pulsation, binarity and close frequency spacing in $delta Scuti ta$ Scuti stars: BQ and BW Cancri. Results of the STEPHI VI campaign in Praesepe Cluster

    NASA Astrophysics Data System (ADS)

    Alvarez, M.; Hernandez, M. M.; Michel, E.; Jiang, S. Y.; Belmonte, J. A.; Chevreton, M.; Massacrier, G.; Liu, Y. Y.; Li, Z. P.; Goupil, M. J.; Cortes, T. Roca; Mangeney, A.; Dolez, N.; Valtier, J. C.; Vidal, I.; Sperl, M.; Talon, S.

    1998-12-01

    New pulsation modes in two delta Scuti stars of Praesepe cluster, BQ and BW Cnc, have been detected during the STEPHI VI campaign in 1995. In particular, 3 frequencies for BQ Cnc and 9 frequencies for BW Cnc have been found above a 99% confidence level. The possibility of the presence of a g-mode present in BQ Cnc is discussed, considering its binarity. The effect of mutual interference between very close detected frequencies in BW Cnc during the observations, is also considered. This last effect reveals the necessity of long-period observing runs, in order to avoid its influence in the final number of detected modes. In such situation, studies of secular amplitude changes can be strongly affected.

  20. 23. Historic American Buildings Survey Alex Bush, Photographer, August 7, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Historic American Buildings Survey Alex Bush, Photographer, August 7, 1935 REAR VIEW, SHOWING SMALL OLD-TIME WINDOW OF SLAVE HOUSE - Forks of Cypress, Savannah Road (Jackson Road), Florence, Lauderdale County, AL

  1. Parallel design of JPEG-LS encoder on graphics processing units

    NASA Astrophysics Data System (ADS)

    Duan, Hao; Fang, Yong; Huang, Bormin

    2012-01-01

    With recent technical advances in graphic processing units (GPUs), GPUs have outperformed CPUs in terms of compute capability and memory bandwidth. Many successful GPU applications to high performance computing have been reported. JPEG-LS is an ISO/IEC standard for lossless image compression which utilizes adaptive context modeling and run-length coding to improve compression ratio. However, adaptive context modeling causes data dependency among adjacent pixels and the run-length coding has to be performed in a sequential way. Hence, using JPEG-LS to compress large-volume hyperspectral image data is quite time-consuming. We implement an efficient parallel JPEG-LS encoder for lossless hyperspectral compression on a NVIDIA GPU using the computer unified device architecture (CUDA) programming technology. We use the block parallel strategy, as well as such CUDA techniques as coalesced global memory access, parallel prefix sum, and asynchronous data transfer. We also show the relation between GPU speedup and AVIRIS block size, as well as the relation between compression ratio and AVIRIS block size. When AVIRIS images are divided into blocks, each with 64×64 pixels, we gain the best GPU performance with 26.3x speedup over its original CPU code.

  2. Black Students in New York State. Crisis and Opportunity. Report of the Education Subcommittee. Volume 7, Education.

    ERIC Educational Resources Information Center

    New York Governor's Advisory Committee for Black Affairs, Albany.

    This document comprises a selected overview of important issues concerning black education in New York State, and recommends specific strategies for improvement. Chapter 1, "Black Student Enrollment, Distribution, and Performance in New York State: Presenting the Data," and chapter 2, "Dropouts in New York: Problems and Prevention…

  3. Short-term variability of 7Be atmospheric deposition and watershed response in a Pacific coastal stream, Monterey Bay, California, USA.

    PubMed

    Conaway, Christopher H; Storlazzi, Curt D; Draut, Amy E; Swarzenski, Peter W

    2013-06-01

    Beryllium-7 is a powerful and commonly used tracer for environmental processes such as watershed sediment provenance, soil erosion, fluvial and nearshore sediment cycling, and atmospheric fallout. However, few studies have quantified temporal or spatial variability of (7)Be accumulation from atmospheric fallout, and parameters that would better define the uses and limitations of this geochemical tracer. We investigated the abundance and variability of (7)Be in atmospheric deposition in both rain events and dry periods, and in stream surface-water samples collected over a ten-month interval at sites near northern Monterey Bay (37°N, 122°W) on the central California coast, a region characterized by a rainy winters, dry summers, and small mountainous streams with flashy hydrology. The range of (7)Be activity in rainwater samples from the main sampling site was 1.3-4.4 Bq L(-1), with a mean (±standard deviation) of 2.2 ± 0.9 Bq L(-1), and a volume-weighted average of 2.0 Bq L(-1). The range of wet atmospheric deposition was 18-188 Bq m(-2) per rain event, with a mean of 72 ± 53 Bq m(-2). Dry deposition fluxes of (7)Be ranged from less than 0.01 up to 0.45 Bq m(-2) d(-1), with an estimated dry season deposition of 7 Bq m(-2) month(-1). Annualized (7)Be atmospheric deposition was approximately 1900 Bq m(-2) yr(-1), with most deposition via rainwater (>95%) and little via dry deposition. Overall, these activities and deposition fluxes are similar to values found in other coastal locations with comparable latitude and Mediterranean-type climate. Particulate (7)Be values in the surface water of the San Lorenzo River in Santa Cruz, California, ranged from <0.01 Bq g(-1) to 0.6 Bq g(-1), with a median activity of 0.26 Bq g(-1). A large storm event in January 2010 characterized by prolonged flooding resulted in the entrainment of (7)Be-depleted sediment, presumably from substantial erosion in the watershed. There were too few particulate (7)Be data over the storm to

  4. Nitrogen Isotopic Disequilibrium in the Cape York III A Iron

    NASA Astrophysics Data System (ADS)

    Zipfel, J.; Kim, Y.; Marti, K.

    1995-09-01

    Cape York is a medium octahedrite of the class III A, which is presumed to have been formed by fractional crystallization of an asteroidal metal core (1). Within the Cape York kamacite-taenite matrix abundant troilite nodules are found. From their elongated form it has been suggested that immiscible S-rich liquids were trapped under the influence of a gravity field. Some of these nodules contain chromite grains, preferentially at the bottom of the troilite/metal boundary (2,3). Minor phases within the troilite are sulfides, phosphates, silica and copper. Carlsbergite (CrN) is exclusively found within the metal matrix. The nitrogen isotopic composition in metal of Cape York was analyzed by several workers and found to be enriched in 14N (delta^(15)N -32.3 to -94.8 per mil) with concentrations varying from 7 to 37 ppm. The large range of N concentrations may reflect artifacts due to experimental difficulties (4), but also might be attributed to varying amounts of CrN within the metal separates. The N in troilite (delta^(15)N -3.8+/-1.2 per mil) was found to be heavier than that observed in metal (4). In one temperature step (1100 degrees C) during stepwise release, nitrogen with a delta^(15)N of -32 per mil was measured, indicating inclusions of an isotopically distinct phase in troilite. In order to trace the nature of the inclusion we determined the N isotopic composition first in a small pilot sample and then in a larger (23.93mg) chromite separate. The latter was stepwise heated at temperatures between 400 and 1000 degrees C, and the release of sample N started at 700 degrees C (delta^(15)N -9.6+/-2.4 per mil). The lightest N component was measured in the 1000 degrees C step with delta^(15)N -56.4+/-13.0 per mil and the average N composition is obtained as delta^(15)N -25.8 per mil. This result supports earlier evidence that nitrogen is isotopically not equilibrated between chromite, surrounding troilite and metal matrix. Possible processes which could lead to a

  5. LS/2000--The Integrated Library System from OCLC.

    ERIC Educational Resources Information Center

    Olson, Susan

    1984-01-01

    Discusses design features of the Online Catalog of LS/2000, OCLC's enhanced version of Integrated Library System. This minicomputer-based system provides bibliographic file maintenance, circulation control, and online catalog searching. Examples of available displays--holdings, full MARC, work forms, keyword entry, index selection, brief citation,…

  6. Inflorescence Development and the Role of LsFT in Regulating Bolting in Lettuce (Lactuca sativa L.).

    PubMed

    Chen, Zijing; Han, Yingyan; Ning, Kang; Ding, Yunyu; Zhao, Wensheng; Yan, Shuangshuang; Luo, Chen; Jiang, Xiaotang; Ge, Danfeng; Liu, Renyi; Wang, Qian; Zhang, Xiaolan

    2017-01-01

    Lettuce ( Lactuca sativa L.) is one of the most important leafy vegetable that is consumed during its vegetative growth. The transition from vegetative to reproductive growth is induced by high temperature, which has significant economic effect on lettuce production. However, the progression of floral transition and the molecular regulation of bolting are largely unknown. Here we morphologically characterized the inflorescence development and functionally analyzed the FLOWERING LOCUS T (LsFT) gene during bolting regulation in lettuce. We described the eight developmental stages during floral transition process. The expression of LsFT was negatively correlated with bolting in different lettuce varieties, and was promoted by heat treatment. Overexpression of LsFT could recover the late-flowering phenotype of ft-2 mutant. Knockdown of LsFT by RNA interference dramatically delayed bolting in lettuce, and failed to respond to high temperature. Therefore, this study dissects the process of inflorescence development and characterizes the role of LsFT in bolting regulation in lettuce.

  7. Inflorescence Development and the Role of LsFT in Regulating Bolting in Lettuce (Lactuca sativa L.)

    PubMed Central

    Chen, Zijing; Han, Yingyan; Ning, Kang; Ding, Yunyu; Zhao, Wensheng; Yan, Shuangshuang; Luo, Chen; Jiang, Xiaotang; Ge, Danfeng; Liu, Renyi; Wang, Qian; Zhang, Xiaolan

    2018-01-01

    Lettuce (Lactuca sativa L.) is one of the most important leafy vegetable that is consumed during its vegetative growth. The transition from vegetative to reproductive growth is induced by high temperature, which has significant economic effect on lettuce production. However, the progression of floral transition and the molecular regulation of bolting are largely unknown. Here we morphologically characterized the inflorescence development and functionally analyzed the FLOWERING LOCUS T (LsFT) gene during bolting regulation in lettuce. We described the eight developmental stages during floral transition process. The expression of LsFT was negatively correlated with bolting in different lettuce varieties, and was promoted by heat treatment. Overexpression of LsFT could recover the late-flowering phenotype of ft-2 mutant. Knockdown of LsFT by RNA interference dramatically delayed bolting in lettuce, and failed to respond to high temperature. Therefore, this study dissects the process of inflorescence development and characterizes the role of LsFT in bolting regulation in lettuce. PMID:29403510

  8. Distal 7q11.23 Duplication, an Emerging Microduplication Syndrome: A Case Report and Further Characterisation.

    PubMed

    Faundes, Víctor; Santa María, Lorena; Morales, Paulina; Curotto, Bianca; Parraguez, María M

    2016-10-01

    Chromosome 7q11.23 duplication syndrome is a well-recognised syndrome which involves the duplication of the same genes located in the Williams-Beuren critical region. However, in 2010, 4 patients were reported with a microduplication only in the HIP1 and YWHAG genes. We refer to this as a distal 7q11.23 duplication (dup7q11.23D). Here, we report the fifth de novo patient with dup7q11.23D, whose symptoms may be explained by YWHAG overexpression as was demonstrated recently in mice and obese patients. Finally, further studies will be necessary to delineate this emerging microduplication syndrome.

  9. A block-based JPEG-LS compression technique with lossless region of interest

    NASA Astrophysics Data System (ADS)

    Deng, Lihua; Huang, Zhenghua; Yao, Shoukui

    2018-03-01

    JPEG-LS lossless compression algorithm is used in many specialized applications that emphasize on the attainment of high fidelity for its lower complexity and better compression ratios than the lossless JPEG standard. But it cannot prevent error diffusion because of the context dependence of the algorithm, and have low compression rate when compared to lossy compression. In this paper, we firstly divide the image into two parts: ROI regions and non-ROI regions. Then we adopt a block-based image compression technique to decrease the range of error diffusion. We provide JPEG-LS lossless compression for the image blocks which include the whole or part region of interest (ROI) and JPEG-LS near lossless compression for the image blocks which are included in the non-ROI (unimportant) regions. Finally, a set of experiments are designed to assess the effectiveness of the proposed compression method.

  10. THE UNUSUAL VARIABLE HOT B SUBDWARF LS IV-14{sup 0}116

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Green, E. M.; Guvenen, B.; O'Malley, C. J.

    2011-06-10

    We first present the results of follow-up photometric observations of the He-rich hot B subdwarf LS IV-14{sup 0}116, which confirm the presence of multiperiodic luminosity variations in the light curve of this star. Rather surprisingly, no other follow-up observations of this kind seem to have been published after the initial suggestion in 2005 that LS IV-14{sup 0}116 could be a pulsating star of a new kind. We were able to extract from our data at least six significant periodicities ranging from 1954 s to 5084 s, including the two oscillations uncovered previously. We also present the results of an analysismore » combining a high signal-to-noise optical spectrum of LS IV-14{sup 0}116 with recently developed non-local thermodynamic equilibrium model atmospheres and synthetic spectra. Our best estimates of the atmospheric parameters of this star are T{sub eff} = 34950 {+-} 250 K, log g = 5.93 {+-} 0.04, and log N(He)/N(H) = -0.62 {+-} 0.03 (formal fitting errors only). These place LS IV-14{sup 0}116 very near the region of maximum instability in the T{sub eff}-log g plane for short-period p-mode pulsators of the hot subdwarf type. If the luminosity variations are indeed due to pulsations, then LS IV-14{sup 0}116 poses a real challenge to current theory: how can such long observed periods (which would have to be associated with medium- to high-order g-modes) be excited at such a high effective temperature and surface gravity, while the short-period p-modes, more typically excited in this domain, are not observed in this particular star?« less

  11. FERMI/LAT Observations of LS 5039

    DOE PAGES

    Abdo, A. A.; Ackermann, M.; Ajello, M.; ...

    2009-10-30

    The first results from observations of the high-mass X-ray binary LS 5039 using the Fermi Gamma-ray Space Telescope data between 2008 August and 2009 June are presented. In this report, our results indicate variability that is consistent with the binary period, with the emission being modulated with a period of 3.903 ± 0.005 days; the first detection of this modulation at GeV energies. The light curve is characterized by a broad peak around superior conjunction in agreement with inverse Compton scattering models. The spectrum is represented by a power law with an exponential cutoff, yielding an overall flux (100 MeV-300more » GeV) of 4.9 ± 0.5(stat) ± 1.8(syst) ×10 –7 photon cm –2 s –1, with a cutoff at 2.1 ± 0.3(stat) ± 1.1(syst) GeV and photon index Γ = 1.9 ± 0.1(stat) ± 0.3(syst). The spectrum is observed to vary with orbital phase, specifically between inferior and superior conjunction. Lastly, we suggest that the presence of a cutoff in the spectrum may be indicative of magnetospheric emission similar to the emission seen in many pulsars by Fermi.« less

  12. Fermi LAT Observations of LS 5039

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdo, A.A.; /Naval Research Lab, Wash., D.C. /Federal City Coll.; Ackermann, M.

    The first results from observations of the high-mass X-ray binary LS 5039 using the Fermi Gamma-ray Space Telescope data between 2008 August and 2009 June are presented. Our results indicate variability that is consistent with the binary period, with the emission being modulated with a period of 3.903 {+-} 0.005 days; the first detection of this modulation at GeV energies. The light curve is characterized by a broad peak around superior conjunction in agreement with inverse Compton scattering models. The spectrum is represented by a power law with an exponential cutoff, yielding an overall flux (100 MeV-300 GeV) of 4.9more » {+-} 0.5(stat) {+-} 1.8(syst) x 10{sup -7} photon cm{sup -2} s{sup -1}, with a cutoff at 2.1 {+-} 0.3(stat) {+-} 1.1(syst) GeV and photon index {Gamma} = 1.9 {+-} 0.1(stat) {+-} 0.3(syst). The spectrum is observed to vary with orbital phase, specifically between inferior and superior conjunction. We suggest that the presence of a cutoff in the spectrum may be indicative of magnetospheric emission similar to the emission seen in many pulsars by Fermi.« less

  13. 7 CFR 500.23 - Fees for commercial photography and cinematography on grounds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Fees for commercial photography and cinematography on grounds. 500.23 Section 500.23 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL ARBORETUM Fee Schedule for Certain Uses of National Arboretum Facilities and Ground...

  14. Short-term variability of 7Be atmospheric deposition and watershed response in a Pacific coastal stream, Monterey Bay, California, USA

    USGS Publications Warehouse

    Conaway, Christopher H.; Storlazzi, Curt D.; Draut, Amy E.; Swarzenski, Peter W.

    2013-01-01

    Beryllium-7 is a powerful and commonly used tracer for environmental processes such as watershed sediment provenance, soil erosion, fluvial and nearshore sediment cycling, and atmospheric fallout. However, few studies have quantified temporal or spatial variability of 7Be accumulation from atmospheric fallout, and parameters that would better define the uses and limitations of this geochemical tracer. We investigated the abundance and variability of 7Be in atmospheric deposition in both rain events and dry periods, and in stream surface-water samples collected over a ten-month interval at sites near northern Monterey Bay (37°N, 122°W) on the central California coast, a region characterized by a rainy winters, dry summers, and small mountainous streams with flashy hydrology. The range of 7Be activity in rainwater samples from the main sampling site was 1.3–4.4 Bq L−1, with a mean (±standard deviation) of 2.2 ± 0.9 Bq L−1, and a volume-weighted average of 2.0 Bq L−1. The range of wet atmospheric deposition was 18–188 Bq m−2 per rain event, with a mean of 72 ± 53 Bq m−2. Dry deposition fluxes of 7Be ranged from less than 0.01 up to 0.45 Bq m−2 d−1, with an estimated dry season deposition of 7 Bq m−2 month−1. Annualized 7Be atmospheric deposition was approximately 1900 Bq m−2 yr−1, with most deposition via rainwater (>95%) and little via dry deposition. Overall, these activities and deposition fluxes are similar to values found in other coastal locations with comparable latitude and Mediterranean-type climate. Particulate 7Be values in the surface water of the San Lorenzo River in Santa Cruz, California, ranged from −1 to 0.6 Bq g−1, with a median activity of 0.26 Bq g−1. A large storm event in January 2010 characterized by prolonged flooding resulted in the entrainment of 7Be-depleted sediment, presumably from substantial erosion in the watershed. There were too few particulate 7Be data over the storm to accurately model a 7Be load

  15. 3-Ls: A Model for Teaching Young Learners

    ERIC Educational Resources Information Center

    Diem, Chuzaimah Dahlan

    2011-01-01

    The fact that EFL literacy in Indonesia is still low led me to conduct this study to cultivate reading habits and increase literacy skills of young learners. Using the 3-Ls--libraries, literature, and literacy--as an instructional model, the study involved five methods: Informational Text Structures; Online Resources; Partnership with Librarians;…

  16. Neuroprotection against apoptosis of SK-N-MC cells using RMP-7- and lactoferrin-grafted liposomes carrying quercetin

    PubMed Central

    Kuo, Yung-Chih; Tsao, Chien-Wei

    2017-01-01

    A drug delivery system of quercetin (QU)-encapsulated liposomes (LS) grafted with RMP-7, a bradykinin analog, and lactoferrin (Lf) was developed to permeate the blood–brain barrier (BBB) and rescue degenerated neurons, acting as an Alzheimer’s disease (AD) pharmacotherapy. This colloidal formulation of QU-encapsulated LS grafted with RMP-7 and Lf (RMP-7-Lf-QU-LS) was used to traverse human brain microvascular endothelial cells (HBMECs) regulated by human astrocytes (HAs) and to treat SK-N-MC cells after an insult with cytotoxic β-amyloid (Aβ) fibrils. We found that surface RMP-7 and Lf enhanced the ability of QU to cross the BBB without inducing strong toxicity and damaging the tight junction. In addition, RMP-7-Lf-QU-LS significantly reduced Aβ-induced neurotoxicity and improved the viability of SK-N-MC cells. Compared with free QU, RMP-7-Lf-QU-LS could also significantly inhibit the expression of phosphorylated c-Jun N terminal kinase, phosphorylated p38, and phosphorylated tau protein at serine 202 by SK-N-MC cells, indicating an important role of RMP-7, Lf, and LS in protecting neurons against apoptosis. RMP-7-Lf-QU-LS is a promising carrier targeting the BBB to prevent Aβ-insulted neurodegeneration and may have potential in managing AD in future clinical applications. PMID:28435263

  17. Simulation of the pentose cycle in lactating rat mammary gland

    PubMed Central

    Haut, Michael J.; London, Jack W.; Garfinkel, David

    1974-01-01

    A computer model representing the pentose cycle, the tricarboxylic acid cycle and glycolysis in slices of lactating rat mammary glands has been constructed. This model is based primarily on the studies, with radioactive chemicals, of Abraham & Chaikoff (1959) [although some of the discrepant data of Katz & Wals (1972) could be accommodated by changing one enzyme activity]. Data obtained by using [1-14C]-, [6-14C]- and [3,4-14C]-glucose were simulated, as well as data obtained by using unlabelled glucose (for which some new experimental data are presented). Much past work on the pentose cycle has been mainly concerned with the division of glucose flow between the pentose cycle and glycolysis, and has relied on the assumption that the system is in steady state (both labelled and unlabelled). This assumption may not apply to lactating rat mammary glands, since the model shows that the percentage flow through the shunt progressively decreased for the first 2h of a 3h experiment, and we were unable to construct a completely steady-state model. The model allows examination of many quantitative features of the system, especially the amount of material passing through key enzymes, some of which appear to be regulated by NADP+ concentrations as proposed by McLean (1960). Supplementary information for this paper has been deposited as Supplementary Publication SUP 50023 at the British Museum (Lending Division) (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973) 131, 5. PMID:4154746

  18. Analysis of storm-tide impacts from Hurricane Sandy in New York

    USGS Publications Warehouse

    Schubert, Christopher E.; Busciolano, Ronald J.; Hearn, Paul P.; Rahav, Ami N.; Behrens, Riley; Finkelstein, Jason S.; Monti, Jack; Simonson, Amy E.

    2015-07-21

    Results of FEMA Hazus Program (HAZUS) flood loss analyses performed for New York counties were compared for extents of storm-tide inundation from Hurricane Sandy mapped (1) pre-storm, (2) on November 11, 2012, and (3) on February 14, 2013. The resulting depictions of estimated total building stock losses document how differing amounts of available USGS data affect the resolution and accuracy of storm-tide inundation extents. Using the most accurate results from the final (February 14, 2013) inundation extent, estimated losses range from $380 million to $5.9 billion for individual New York counties; total estimated aggregate losses are about $23 billion for all New York counties. Quality of the inundation extents used in HAZUS analyses has a substantial effect on final results. These findings can be used to inform future post-storm reconstruction planning and estimation of insurance claims.

  19. 15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the... Department of Commerce organizational units of implementation and procedures. Following are roles and...) Otherwise determine and control the use of missing children materials and information by the Operating Unit...

  20. Assessment of Pathological Traits in DSM-5 Personality Disorders by the DAPP-BQ: How Do These Traits Relate to the Six Personality Disorder Types of the Alternative Model?

    PubMed

    Berghuis, Han; Ingenhoven, Theo J M; van der Heijden, Paul T; Rossi, Gina M P; Schotte, Chris K W

    2017-11-09

    The six personality disorder (PD) types in DSM-5 section III are intended to resemble their DSM-IV/DSM-5 section II PD counterparts, but are now described by the level of personality functioning (criterion A) and an assigned trait profile (criterion B). However, concerns have been raised about the validity of these PD types. The present study examined the continuity between the DSM-IV/DSM-5 section II PDs and the corresponding trait profiles of the six DSM-5 section III PDs in a sample of 350 Dutch psychiatric patients. Facets of the Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ) were presumed as representations (proxies) of the DSM-5 section III traits. Correlational patterns between the DAPP-BQ and the six PDs were consistent with previous research between DAPP-BQ and DSM-IV PDs. Moreover, DAPP-BQ proxies were able to predict the six selected PDs. However, the assigned trait profile for each PD didn't fully match the corresponding PD.

  1. Association of neighborhood-level factors with hospitalization for community-associated methicillin-resistant Staphylococcus aureus, New York City, 2006: a multilevel observational study.

    PubMed

    Farr, Amanda M; Marx, Melissa A; Weiss, Don; Nash, Denis

    2013-02-13

    Hospitalizations with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection have increased in New York City, with substantial geographic variation across neighborhoods. While individual-level risk factors, such as age, sex, HIV infection, and diabetes have been described, the role of neighborhood-level factors (e.g., neighborhood HIV prevalence or income) has not been examined. To explore plausible neighborhood-level factors associated with CA-MRSA-related hospitalizations, a retrospective analysis was conducted using New York City hospital discharges from 2006 and New York City-specific survey and health department surveillance data. CA-MRSA-related hospitalizations were identified using diagnosis codes and admission information. Associations were determined by using sex-specific multilevel logistic regression. The CA-MRSA hospitalization rate varied by more than six-fold across New York City neighborhoods. Females hospitalized with CA-MRSA had more than twice the odds of residing in neighborhoods in the highest quintile of HIV prevalence (adjusted odds ratio [AOR](Q5 vs. Q1) 2.3, 95% CI: 1.2, 2.7). Both males and females hospitalized with CA-MRSA had nearly twice the odds of residing in neighborhoods with moderately high proportion of men who have sex with men (MSM) residing in the neighborhood (males: AOR(Q4 vs. Q1) 1.7, 95% CI: 1.1, 2.7; females: AOR(Q4 vs. Q1) 2.0, 95% CI: 1.1, 3.6); but this association did not hold for neighborhoods in the highest quintile (males: AOR(Q5 vs. Q1) 1.2, 95% CI: 0.76, 1.8; females: AOR(Q5 vs. Q1) 1.5, 95% CI: 0.82, 2.7). Neighborhood-level characteristics were associated with CA-MRSA hospitalization odds, independent of individual-level risk factors, and may contribute to the population-level burden of CA-MRSA infection.

  2. Technical Report, Onondaga Lake, New York, Main Report

    DTIC Science & Technology

    1992-01-01

    growth . Section 3 of this report will expand upon the specific water quality problems. EXISTING CONDITIONS Page 23 Table V - Comparison of Current...This technical report on Ononidaga Lake, New York has compi led existing data to determine which water quality and enviromental enhancements are... bacteria is a problem during storm events causing contravention of the State swimming standards. The source of the problem has been identified as the

  3. The Bacillus subtilis Conjugative Plasmid pLS20 Encodes Two Ribbon-Helix-Helix Type Auxiliary Relaxosome Proteins That Are Essential for Conjugation.

    PubMed

    Miguel-Arribas, Andrés; Hao, Jian-An; Luque-Ortega, Juan R; Ramachandran, Gayetri; Val-Calvo, Jorge; Gago-Córdoba, César; González-Álvarez, Daniel; Abia, David; Alfonso, Carlos; Wu, Ling J; Meijer, Wilfried J J

    2017-01-01

    Bacterial conjugation is the process by which a conjugative element (CE) is transferred horizontally from a donor to a recipient cell via a connecting pore. One of the first steps in the conjugation process is the formation of a nucleoprotein complex at the origin of transfer ( oriT ), where one of the components of the nucleoprotein complex, the relaxase, introduces a site- and strand specific nick to initiate the transfer of a single DNA strand into the recipient cell. In most cases, the nucleoprotein complex involves, besides the relaxase, one or more additional proteins, named auxiliary proteins, which are encoded by the CE and/or the host. The conjugative plasmid pLS20 replicates in the Gram-positive Firmicute bacterium Bacillus subtilis . We have recently identified the relaxase gene and the oriT of pLS20, which are separated by a region of almost 1 kb. Here we show that this region contains two auxiliary genes that we name aux1 LS20 and aux2 LS20 , and which we show are essential for conjugation. Both Aux1 LS20 and Aux2 LS20 are predicted to contain a Ribbon-Helix-Helix DNA binding motif near their N-terminus. Analyses of the purified proteins show that Aux1 LS20 and Aux2 LS20 form tetramers and hexamers in solution, respectively, and that they both bind preferentially to oriT LS20 , although with different characteristics and specificities. In silico analyses revealed that genes encoding homologs of Aux1 LS20 and/or Aux2 LS20 are located upstream of almost 400 relaxase genes of the Rel LS20 family (MOB L ) of relaxases. Thus, Aux1 LS20 and Aux2 LS20 of pLS20 constitute the founding member of the first two families of auxiliary proteins described for CEs of Gram-positive origin.

  4. 7 CFR 652.23 - Certification process for private-sector entities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Certification process for private-sector entities. 652... ASSISTANCE Certification § 652.23 Certification process for private-sector entities. (a) A private sector... individual basis as part of the private-sector entity's certification and ensures that the requirements set...

  5. Sources of enhanced SO2 in the tropical Western Pacific UT/LS

    NASA Astrophysics Data System (ADS)

    Rollins, A. W.; Thornberry, T. D.; Liu, S.; Ray, E. A.; Atlas, E. L.; Navarro, M. A.; Schauffler, S.; Bui, T. V.; Gao, R. S.

    2017-12-01

    Sulfur dioxide is an important precursor to aerosols in the stratosphere. Typical mixing ratios of SO2 in the tropical upper troposphere and lower stratosphere (UT/LS) are on the order of a few pptv. Convective transport of SO2 from source regions near the surface can produce local enhancements in the UT/LS of more than one order of magnitude compared to typical values. These local enhancements if sufficient in number and/or magnitude might be important for the stratospheric aerosol budget. Here we analyze three such local enhancements observed during the NASA POSIDON mission. We use back-trajectories and tracer species to demonstrate that significant SO2 in the UT/LS on different occasions originated from 1) a volcano in Papua New Guinea, 2) convection over Asia, and 3) transport of air by a typhoon. These examples that were observed on three out of ten flights indicate that significant SO2 over the Western Pacific is not uncommon, and may be an important fraction of the stratospheric aerosol budget.

  6. Palliative care clinicians' knowledge of the law regarding the use of the Deprivation of Liberty Safeguards (DoLS).

    PubMed

    Barry, Caroline; Spathis, Anna; Treaddell, Sarah; Carding, Sally; Barclay, Stephen

    2017-04-24

    To examine palliative care clinicians' level of knowledge of the law regarding the use of the Deprivation of Liberty Safeguards (DoLS). Regional postal survey of palliative care clinicians working in hospices in the East of England, undertaken in April 2015. Clinicians' level of knowledge was assessed by their response to 7 factual questions. Data regarding self-reported levels of confidence in applying the Safeguards was collected, alongside information regarding the number of times they had used DoLS in practice. A free-text section invited additional comments from participants. There were 47 responses from 14 different organisations; a response rate of 68%. Respondents included consultants, specialty and associate specialists, registrars, nurses and social workers. Higher self-reported confidence and training in the use of DoLS was associated with higher factual knowledge. Consultants had the highest level of knowledge, training and experience. Doctors of other grades, nurses and social workers recorded less knowledge and experience and scored lower in the knowledge sections. The free-text comments revealed difficulty applying the Safeguards in practice, particularly among the consultant responses, based around several themes: insufficient guidance on how to use the Safeguards, process after death, uncertainty as to relevance to palliative care and delays in assessments. Clinicians working in palliative care have good levels of knowledge of the DoLS. Despite this concerns were raised, particularly by consultants; uncertainty as to when they should be used and the relevance of the Safeguards in clinical practice. Further guidance should be given to clinicians working in this specialty to ensure that clinical practice is both lawful and in the patients' best interests. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  7. Effective collision strengths for fine-structure forbidden transitions among the 3s^23p^3 levels of AR IV

    NASA Astrophysics Data System (ADS)

    Ramsbottom, C. A.; Bell, K. L.; Keenan, F. P.

    1997-01-01

    The multichannel R-matrix method is used to compute electron impact excitation collision strengths in Ar iv for all fine-structure transitions among the ^4S^o, ^2D^o and ^2P^o levels in the 3s^23p^3 ground configuration. Included in the expansion of the total wavefunction are the lowest 13 LS target eigenstates of Ar iv formed from the 3s^23p^3, 3s3p^4 and 3s^23p^23d configurations. The effective collision strengths, obtained by averaging the electron collision strengths over a Maxwellian distribution of electron velocities, are presented for all 10 fine-structure transitions over a wide range of electron temperatures of astrophysical interest (T_e=2000-100 000K). Comparisons are made with an earlier 7-state close-coupling calculation by Zeippen, Butler & Le Bourlot, and significant differences are found to occur for many of the forbidden transitions considered, in particular those involving the ^4S^o ground state, where discrepancies of up to a factor of 3 are found in the low-temperature region.

  8. LCM-seq reveals the crucial role of LsSOC1 in heat-promoted bolting of lettuce (Lactuca sativa L.).

    PubMed

    Chen, Zijing; Zhao, Wensheng; Ge, Danfeng; Han, Yingyan; Ning, Kang; Luo, Chen; Wang, Shenglin; Liu, Renyi; Zhang, Xiaolan; Wang, Qian

    2018-05-17

    Lettuce (Lactuca sativa L.) is one of the most economically important vegetables. The floral transition in lettuce is accelerated under high temperatures, which can significantly decrease yields. However, the molecular mechanism underlying the floral tranition in lettuce is poorly known. Using laser capture microdissection coupled with RNA sequencing, we isolated shoot apical meristem cells from the bolting-sensitive lettuce line S39 at four critical stages of development. Subsequently, we screened specifically for the flowering-related gene LsSOC1 during the floral transition through comparative transcriptomic analysis. Molecular biology, developmental biology, and biochemical tools were combined to investigate the biological function of LsSOC1 in lettuce. LsSOC1 knockdown by RNA interference resulted in a significant delay in the timing of bolting and insensitivity to high temperature, which indicated that LsSOC1 functions as an activator during heat-promoted bolting in lettuce. We determined that two heat-shock transcription factors, HsfA1e and HsfA4c, bound to the promoter of LsSOC1 to confirm that LsSOC1 played an important role in heat-promoted bolting. This study indicates that LsSOC1 plays a crucial role in the heat-promoted bolting process in lettuce. Further investigation of LsSOC1 may be useful for clarification of the bolting mechanism in lettuce. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  9. LS 5039 - the counterpart of the unidentified MeV source GRO J1823-12

    NASA Astrophysics Data System (ADS)

    Collmar, W.; Zhang, S.

    2014-05-01

    Context. The COMPTEL experiment on CGRO observed the γ-ray sky at energies from 0.75 MeV to 30 MeV between April 1991 and June 2000. COMPTEL detected many γ-ray sources, among them an unidentified one labeled GRO J1823-12. It is located near l/b = 17.5°/-0.5° and positionally consistent with the prominent γ-ray binary LS 5039. Aims: LS 5039 was established as a γ-ray source at TeV energies by HESS and at GeV energies by Fermi/LAT during recent years, whose γ-ray radiation is modulated along its binary orbit. Given this new information we reanalyzed the COMPTEL data of GRO J1823-12 including an orbital-resolved analysis. Methods: We applied the standard methods, proper event selections and data binning with subsequent maximum-likelihood deconvolution, to analyze the COMPTEL data. In addition we developed a tool for selecting and binning the COMPTEL data in a phase-resolved manner. We present the orbit-averaged, as well as orbit-resolved MeV analyses, light curves, and spectra, and put them into a multifrequency context. Results: The COMPTEL data show a significant MeV source, which is positionally consistent with LS 5039, but also with other closeby Fermi/LAT sources. The orbit-resolved analysis provides strong evidence, at about the 3σ level, that the MeV flux of GRO J1823-12 is modulated along the binary orbit of about 3.9 days of LS 5039. We show that at MeV energies, the source is brighter at the orbital part around the inferior conjunction than at the part of the superior conjunction, so it is in phase with X-rays and TeV γ-rays, but in anti-phase with GeV γ-rays. The high-energy spectral energy distribution (X-rays to TeV γ-rays) shows the high-energy emission maximum of LS 5039 at MeV energies. Conclusions: We conclude that the COMPTEL source GRO J1823-12 is the counterpart of the microquasar LS 5039, at least for the majority of its MeV emission. The COMPTEL fluxes, put into multifrequency perspective, provide new constraints on the modeling of

  10. LS-align: an atom-level, flexible ligand structural alignment algorithm for high-throughput virtual screening.

    PubMed

    Hu, Jun; Liu, Zi; Yu, Dong-Jun; Zhang, Yang

    2018-02-15

    Sequence-order independent structural comparison, also called structural alignment, of small ligand molecules is often needed for computer-aided virtual drug screening. Although many ligand structure alignment programs are proposed, most of them build the alignments based on rigid-body shape comparison which cannot provide atom-specific alignment information nor allow structural variation; both abilities are critical to efficient high-throughput virtual screening. We propose a novel ligand comparison algorithm, LS-align, to generate fast and accurate atom-level structural alignments of ligand molecules, through an iterative heuristic search of the target function that combines inter-atom distance with mass and chemical bond comparisons. LS-align contains two modules of Rigid-LS-align and Flexi-LS-align, designed for rigid-body and flexible alignments, respectively, where a ligand-size independent, statistics-based scoring function is developed to evaluate the similarity of ligand molecules relative to random ligand pairs. Large-scale benchmark tests are performed on prioritizing chemical ligands of 102 protein targets involving 1,415,871 candidate compounds from the DUD-E (Database of Useful Decoys: Enhanced) database, where LS-align achieves an average enrichment factor (EF) of 22.0 at the 1% cutoff and the AUC score of 0.75, which are significantly higher than other state-of-the-art methods. Detailed data analyses show that the advanced performance is mainly attributed to the design of the target function that combines structural and chemical information to enhance the sensitivity of recognizing subtle difference of ligand molecules and the introduces of structural flexibility that help capture the conformational changes induced by the ligand-receptor binding interactions. These data demonstrate a new avenue to improve the virtual screening efficiency through the development of sensitive ligand structural alignments. http://zhanglab.ccmb.med.umich.edu/LS

  11. 47 CFR 7.23 - Actions by the Commission on its own motion.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Actions by the Commission on its own motion. 7... INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.23 Actions by the Commission on its own motion. The Commission may on its own motion conduct such inquiries and hold such...

  12. 47 CFR 7.23 - Actions by the Commission on its own motion.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Actions by the Commission on its own motion. 7... INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.23 Actions by the Commission on its own motion. The Commission may on its own motion conduct such inquiries and hold such...

  13. New York's Children in 1989: Society at Risk. A Report of New York State Project 2000.

    ERIC Educational Resources Information Center

    Schoggen, Phil; Schoggen, Maxine

    This report reviews the current conditions of New York's children. Topics include: (1) demographic conditions, trends and projections; (2) economic conditions; (3) child care; (4) education; (5) health and nutrition; (6) school-age pregnancy and child bearing; (7) alcohol and drug abuse; and (8) racial and ethnic group inequality. The report…

  14. Error-prone PCR mutation of Ls-EPSPS gene from Liriope spicata conferring to its enhanced glyphosate-resistance.

    PubMed

    Mao, Chanjuan; Xie, Hongjie; Chen, Shiguo; Valverde, Bernal E; Qiang, Sheng

    2017-09-01

    Liriope spicata (Thunb.) Lour has a unique LsEPSPS structure contributing to the highest-ever-recognized natural glyphosate tolerance. The transformed LsEPSPS confers increased glyphosate resistance to E. coli and A. thaliana. However, the increased glyphosate-resistance level is not high enough to be of commercial value. Therefore, LsEPSPS was subjected to error-prone PCR to screen mutant EPSPS genes capable of endowing higher resistance levels. A mutant designated as ELs-EPSPS having five mutated amino acids (37Val, 67Asn, 277Ser, 351Gly and 422Gly) was selected for its ability to confer improved resistance to glyphosate. Expression of ELs-EPSPS in recombinant E. coli BL21 (DE3) strains enhanced resistance to glyphosate in comparison to both the LsEPSPS-transformed and -untransformed controls. Furthermore, transgenic ELs-EPSPS A. thaliana was about 5.4 fold and 2-fold resistance to glyphosate compared with the wild-type and the Ls-EPSPS-transgenic plants, respectively. Therefore, the mutated ELs-EPSPS gene has potential value for has potential for the development of glyphosate-resistant crops. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. 7 CFR 3431.23 - Service to Federal Government in emergency situations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Service to Federal Government in emergency situations...) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.23...

  16. 75 FR 19957 - New York State Electric & Gas Corporation; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP10-100-000] New York State Electric & Gas Corporation; Notice of Application April 9, 2010. Take notice that on March 24, 2010, New York State Electric & Gas Corporation (NYSEG), filed with the Commission an application under section 7...

  17. A COMPARATIVE STUDY OF DIURNAL VARIATION OF RADON AND THORON CONCENTRATIONS IN INDOOR ENVIRONMENT.

    PubMed

    Pant, Preeti; Kandari, Tushar; Prasad, Mukesh; Ramola, R C

    2016-10-01

    The diurnal measurements of radon and thoron concentrations were performed in the indoor environment of Nuclear Research Laboratory, Badshahi Thaul, Tehri Garhwal, Uttarakhand, India by using AlphaGUARD, Portable Radon Monitor (SMART RnDuo) and RAD7. Using AlphaGUARD, the radon concentration was found to vary from 8 to 94 Bq m -3 with an average of 41.5±22.2 Bq m -3 Using Portable Radon Monitor (SMART RnDuo), the concentration was found to vary from 2 to 101 Bq m -3 with an average of 41.7±23.6 Bq m -3 , and with RAD7, the concentration was found to vary from 3 to 99 Bq m -3 with an average of 40±20.3 Bqm -3 While the thoron concentration using Portable Radon Monitor (SMART RnDuo) was found to vary from 4 to 65 Bq m -3 with an average of 17.3±12.9 Bqm -3 , and using RAD7, the concentration was found to vary from 5 to 90 Bq m -3 with an average of 29.8±17.3 Bq m -3 . © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Life’s Simple 7 and Risk of Incident Stroke: REasons for Geographic And Racial Differences in Stroke (REGARDS) Study

    PubMed Central

    Kulshreshtha, Ambar; Vaccarino, Viola; Judd, Suzanne; Howard, Virginia J.; McClellan, William; Muntner, Paul; Hong, Yuling; Safford, Monika; Goyal, Abhinav; Cushman, Mary

    2013-01-01

    Background and Purpose The American Heart Association developed Life’s Simple 7 (LS7) as a metric defining cardiovascular health. We investigated the association between LS7 and incident stroke in black and white Americans. Methods REGARDS is a national population-based cohort of 30,239 blacks and whites, aged ≥45 years, sampled from the US population in 2003 – 2007. Data were collected by telephone, self-administered questionnaires and an in-home exam. Incident strokes were identified through bi-annual participant contact followed by adjudication of medical records. Levels of the LS7 components (blood pressure, cholesterol, glucose, body mass index, smoking, physical activity, and diet) were each coded as poor (0 point), intermediate (1 point) or ideal (2 points) health. An overall LS7 score was categorized as inadequate (0–4), average (5–9) or optimum (10–14) cardiovascular health. Results Among 22,914 subjects with LS7 data and no previous cardiovascular disease, there were 432 incident strokes over 4.9 years of follow-up. After adjusting for demographics, socioeconomic status, and region of residence, each better health category of the LS7 score was associated with a 25% lower risk of stroke (HR=0.75, 95% CI = 0.63, 0.90). The association was similar for blacks and whites (interaction p-value = 0.55). A one point higher LS7 score was associated with an 8% lower risk of stroke (HR=0.92, 95% CI=0.88, 0.95). Conclusion In both blacks and whites better cardiovascular health, based on the LS7 score, is associated with lower risk of stroke, and a small difference in scores was an important stroke determinant. PMID:23743971

  19. Confirmatory factor analysis of the Revised UCLA Loneliness Scale (UCLA LS-R) in individuals over 65.

    PubMed

    Ausín, Berta; Muñoz, Manuel; Martín, Teresa; Pérez-Santos, Eloísa; Castellanos, Miguel Ángel

    2018-01-08

    The UCLA LS-R is the most extensively used scale to assess loneliness. However, few studies examine the scale's use on older individuals. The goal of the study is to analyse the suitability of the scale´s structure for assessing older individuals. The UCLA LS-R scale was administered to a random sample of 409 community-dwelling residents of Madrid (53% women) aged 65-84 years (obtained from the MentDis_ICF65+ study). Confirmatory factor analysis was used to assess the factor structure of the UCLA LS-R. The internal consistency of the scale obtained a Cronbach's alpha of .85. All the analysed models of factor structure of the UCLA LS-R achieved a fairly good fit and RMSEA values over .80. The models that best fit the empirical data are those of Hojat (1982) and Borges et al. (2008). The data suggest an equivalent effectiveness of UCLA LS-R in adults under 65 and over 65, which may indicate a similar structure of the loneliness construct in both populations. This outcome is consistent with the idea that loneliness has two dimensions: emotional loneliness and social loneliness. The use of short measures that are easy to apply and interpret should help primary care professionals identify loneliness problems in older individuals sooner and more accurately.

  20. LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources.

    PubMed

    Karchin, Rachel; Diekhans, Mark; Kelly, Libusha; Thomas, Daryl J; Pieper, Ursula; Eswar, Narayanan; Haussler, David; Sali, Andrej

    2005-06-15

    The NCBI dbSNP database lists over 9 million single nucleotide polymorphisms (SNPs) in the human genome, but currently contains limited annotation information. SNPs that result in amino acid residue changes (nsSNPs) are of critical importance in variation between individuals, including disease and drug sensitivity. We have developed LS-SNP, a genomic scale software pipeline to annotate nsSNPs. LS-SNP comprehensively maps nsSNPs onto protein sequences, functional pathways and comparative protein structure models, and predicts positions where nsSNPs destabilize proteins, interfere with the formation of domain-domain interfaces, have an effect on protein-ligand binding or severely impact human health. It currently annotates 28,043 validated SNPs that produce amino acid residue substitutions in human proteins from the SwissProt/TrEMBL database. Annotations can be viewed via a web interface either in the context of a genomic region or by selecting sets of SNPs, genes, proteins or pathways. These results are useful for identifying candidate functional SNPs within a gene, haplotype or pathway and in probing molecular mechanisms responsible for functional impacts of nsSNPs. http://www.salilab.org/LS-SNP CONTACT: rachelk@salilab.org http://salilab.org/LS-SNP/supp-info.pdf.

  1. Designing for Learner Success (D4LS) at Otago Polytechnic: From an E-learning Designer's Perspective

    ERIC Educational Resources Information Center

    Gedera, Dilani S. P.

    2016-01-01

    Otago Polytechnic (OP) is currently redesigning and redeveloping its programmes and courses under an institution-wide initiative called Designing for Learner Success (D4LS). This initiative has several phases--design, development, delivery, and evaluation. This article focuses on the processes and considerations in the development phase of D4LS,…

  2. Sirex noctilio, the New York story

    Treesearch

    Carolyn Klass; E. Richard Hoebeke

    2007-01-01

    Sirex wood wasp, (Sirex noctilio Fabricius), was first identified in February 2005 from a Lindgren funnel trap taken September 7, 2004 in Fulton, NY (Oswego County). We followed the development of the events in New York chronologically from this first identification to the results of an expanded trapping program in 2005.

  3. [Rapid determination of COD in aquaculture water based on LS-SVM with ultraviolet/visible spectroscopy].

    PubMed

    Liu, Xue-Mei; Zhang, Hai-Liang

    2014-10-01

    Ultraviolet/visible (UV/Vis) spectroscopy was studied for the rapid determination of chemical oxygen demand (COD), which was an indicator to measure the concentration of organic matter in aquaculture water. In order to reduce the influence of the absolute noises of the spectra, the extracted 135 absorbance spectra were preprocessed by Savitzky-Golay smoothing (SG), EMD, and wavelet transform (WT) methods. The preprocessed spectra were then used to select latent variables (LVs) by partial least squares (PLS) methods. Partial least squares (PLS) was used to build models with the full spectra, and back- propagation neural network (BPNN) and least square support vector machine (LS-SVM) were applied to build models with the selected LVs. The overall results showed that BPNN and LS-SVM models performed better than PLS models, and the LS-SVM models with LVs based on WT preprocessed spectra obtained the best results with the determination coefficient (r2) and RMSE being 0. 83 and 14. 78 mg · L(-1) for calibration set, and 0.82 and 14.82 mg · L(-1) for the prediction set respectively. The method showed the best performance in LS-SVM model. The results indicated that it was feasible to use UV/Vis with LVs which were obtained by PLS method, combined with LS-SVM calibration could be applied to the rapid and accurate determination of COD in aquaculture water. Moreover, this study laid the foundation for further implementation of online analysis of aquaculture water and rapid determination of other water quality parameters.

  4. 7 CFR 3431.23 - Service to Federal government in emergency situations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... INSTITUTE OF FOOD AND AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.23 Service to Federal government in emergency situations... 7 Agriculture 15 2014-01-01 2014-01-01 false Service to Federal government in emergency situations...

  5. 7 CFR 3431.23 - Service to Federal government in emergency situations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... INSTITUTE OF FOOD AND AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.23 Service to Federal government in emergency situations... 7 Agriculture 15 2013-01-01 2013-01-01 false Service to Federal government in emergency situations...

  6. 7 CFR 3431.23 - Service to Federal government in emergency situations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... INSTITUTE OF FOOD AND AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.23 Service to Federal government in emergency situations... 7 Agriculture 15 2012-01-01 2012-01-01 false Service to Federal government in emergency situations...

  7. 7 CFR 3431.23 - Service to Federal government in emergency situations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... INSTITUTE OF FOOD AND AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.23 Service to Federal government in emergency situations... 7 Agriculture 15 2011-01-01 2011-01-01 false Service to Federal government in emergency situations...

  8. A consensus least squares support vector regression (LS-SVR) for analysis of near-infrared spectra of plant samples.

    PubMed

    Li, Yankun; Shao, Xueguang; Cai, Wensheng

    2007-04-15

    Consensus modeling of combining the results of multiple independent models to produce a single prediction avoids the instability of single model. Based on the principle of consensus modeling, a consensus least squares support vector regression (LS-SVR) method for calibrating the near-infrared (NIR) spectra was proposed. In the proposed approach, NIR spectra of plant samples were firstly preprocessed using discrete wavelet transform (DWT) for filtering the spectral background and noise, then, consensus LS-SVR technique was used for building the calibration model. With an optimization of the parameters involved in the modeling, a satisfied model was achieved for predicting the content of reducing sugar in plant samples. The predicted results show that consensus LS-SVR model is more robust and reliable than the conventional partial least squares (PLS) and LS-SVR methods.

  9. Natural radioactivity determination in samples of Peperomia pellucida commonly used as a medicinal herb.

    PubMed

    Sussa, Fábio V; Damatto, Sandra R; Alencar, Marcos M; Mazzilli, Barbara P; Silva, Paulo S C

    2013-02-01

    The concentration of (238)U, (232)Th, (230)Th, (226)Ra, (228)Ra and (210)Pb were determined in samples of Peperomia pellucida and in the surrounding soil, by alpha spectrometry and gross alpha and beta counting. The radionuclide activity concentrations ranged from 4.3 to 38 Bq kg(-1), 1.7-124 Bq kg(-1), 2.1-38 Bq kg(-1), 8.5-37 Bq kg(-1), 3.2-46 Bq kg(-1), 39-93 Bq kg(-1), respectively. In the plant extractions and infusions as used for consumption, the mean recoveries were from 23% to 60% in maceration and 24-75% in infusion. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. 7 CFR 51.23 - Report of inspection results prior to issuance of formal report.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Report of inspection results prior to issuance of formal report. 51.23 Section 51.23 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETIN...

  11. 7 CFR 51.23 - Report of inspection results prior to issuance of formal report.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Report of inspection results prior to issuance of formal report. 51.23 Section 51.23 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETIN...

  12. 7 CFR 51.23 - Report of inspection results prior to issuance of formal report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Report of inspection results prior to issuance of formal report. 51.23 Section 51.23 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETIN...

  13. 7 CFR 51.23 - Report of inspection results prior to issuance of formal report.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Report of inspection results prior to issuance of formal report. 51.23 Section 51.23 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETIN...

  14. Prevalence and Clinical Attributes of Congenital Microcephaly - New York, 2013-2015.

    PubMed

    Graham, Krishika A; Fox, Deborah J; Talati, Achala; Pantea, Cristian; Brady, Laura; Carter, Sondra L; Friedenberg, Eric; Vora, Neil M; Browne, Marilyn L; Lee, Christopher T

    2017-02-10

    Congenital Zika virus infection can cause microcephaly and other severe fetal neurological anomalies (1). To inform microcephaly surveillance efforts and assess ascertainment sources, the New York State Department of Health and the New York City Department of Health and Mental Hygiene sought to determine the prevalence of microcephaly in New York during 2013-2015, before known importation of Zika virus infections. Suspected newborn microcephaly diagnoses were identified from 1) reports submitted by birth hospitals in response to a request and 2) queries of a hospital administrative discharge database for newborn microcephaly diagnoses. Anthropometric measurements, maternal demographics, and pregnancy characteristics were abstracted from newborn records from both sources. Diagnoses were classified using microcephaly case definitions developed by CDC and the National Birth Defects Prevention Network (NBDPN) (2). During 2013-2015, 284 newborns in New York met the case definition for severe congenital microcephaly (prevalence = 4.2 per 10,000 live births). Most newborns with severe congenital microcephaly were identified by both sources; 263 (93%) were identified through hospital requests and 256 (90%) were identified through administrative discharge data. The proportions of newborns with severe congenital microcephaly who were black (30%) or Hispanic (31%) were higher than the observed proportions of black (15%) or Hispanic (23%) infants among New York live births. Fifty-eight percent of newborns with severe congenital microcephaly were born to mothers with pregnancy complications or who had in utero or perinatal infections or teratogenic exposures, genetic disorders, or family histories of birth defects.

  15. LS-CAP: an algorithm for identifying cytogenetic aberrations in hepatocellular carcinoma using microarray data.

    PubMed

    He, Xianmin; Wei, Qing; Sun, Meiqian; Fu, Xuping; Fan, Sichang; Li, Yao

    2006-05-01

    Biological techniques such as Array-Comparative genomic hybridization (CGH), fluorescent in situ hybridization (FISH) and affymetrix single nucleotide pleomorphism (SNP) array have been used to detect cytogenetic aberrations. However, on genomic scale, these techniques are labor intensive and time consuming. Comparative genomic microarray analysis (CGMA) has been used to identify cytogenetic changes in hepatocellular carcinoma (HCC) using gene expression microarray data. However, CGMA algorithm can not give precise localization of aberrations, fails to identify small cytogenetic changes, and exhibits false negatives and positives. Locally un-weighted smoothing cytogenetic aberrations prediction (LS-CAP) based on local smoothing and binomial distribution can be expected to address these problems. LS-CAP algorithm was built and used on HCC microarray profiles. Eighteen cytogenetic abnormalities were identified, among them 5 were reported previously, and 12 were proven by CGH studies. LS-CAP effectively reduced the false negatives and positives, and precisely located small fragments with cytogenetic aberrations.

  16. Nanoscale characterization and local piezoelectric properties of lead-free KNN-LT-LS thin films

    NASA Astrophysics Data System (ADS)

    Abazari, M.; Choi, T.; Cheong, S.-W.; Safari, A.

    2010-01-01

    We report the observation of domain structure and piezoelectric properties of pure and Mn-doped (K0.44,Na0.52,Li0.04)(Nb0.84,Ta0.1,Sb0.06)O3 (KNN-LT-LS) thin films on SrTiO3 substrates. It is revealed that, using piezoresponse force microscopy, ferroelectric domain structure in such 500 nm thin films comprised of primarily 180° domains. This was in accordance with the tetragonal structure of the films, confirmed by relative permittivity measurements and x-ray diffraction patterns. Effective piezoelectric coefficient (d33) of the films were calculated using piezoelectric displacement curves and shown to be ~53 pm V-1 for pure KNN-LT-LS thin films. This value is among the highest values reported for an epitaxial lead-free thin film and shows a great potential for KNN-LT-LS to serve as an alternative to PZT thin films in future applications.

  17. Inverse European Latitudinal Cline at the timeless Locus of Drosophila melanogaster Reveals Selection on a Clock Gene: Population Genetics of ls-tim.

    PubMed

    Zonato, Valeria; Vanin, Stefano; Costa, Rodolfo; Tauber, Eran; Kyriacou, Charalambos P

    2018-02-01

    The spread of adaptive genetic variants in populations is a cornerstone of evolutionary theory but with relatively few biologically well-understood examples. Previous work on the ls-tim variant of timeless, which encodes the light-sensitive circadian regulator in Drosophila melanogaster, suggests that it may have originated in southeastern Italy. Flies characterized by the new allele show photoperiod-related phenotypes likely to be adaptive in seasonal environments. ls-tim may be spreading from its point of origin in Italy by directional selection, but there are alternative explanations for its observed clinal geographical distribution, including balancing selection and demography. From population analyses of ls-tim frequencies collected on the eastern side of the Iberian Peninsula, we show that ls-tim frequencies are inverted compared with those in Italy. This pattern is consistent with a scenario of directional selection rather than latitude-associated balancing selection. Neutrality tests further reveal the signature of directional selection at the ls-tim site, which is reduced a few kb pairs either side of ls-tim. A reanalysis of allele frequencies from a large number of microsatellite loci do not demonstrate any frequent ls-tim-like spatial patterns, so a general demographic effect or population expansion from southeastern Italy cannot readily explain current ls-tim frequencies. Finally, a revised estimate of the age of ls-tim allele using linkage disequilibrium and coalescent-based approaches reveals that it may be only 300 to 3000 years old, perhaps explaining why it has not yet gone to fixation. ls-tim thus provides a rare temporal snapshot of a new allele that has come under selection before it reaches equilibrium.

  18. 7Be behaviour and meteorological conditions associated with 7Be peak events in Spain.

    PubMed

    Hernández-Ceballos, M A; Brattich, E; Lozano, R L; Cinelli, G

    2017-01-01

    This work regards a comprehensive analysis of the overall distribution of 7 Be activity concentrations in Spain and the synoptic meteorological conditions associated with the highest 7 Be peaks (>8 mBq/m 3 ). The use of four sampling stations (Barcelona, Bilbao, Madrid, and Sevilla) included in REMdb, with different latitudinal location, as well as the relatively long time period used in this study (2001-2010), allowed to improve the understanding of 7 Be spatio-temporal distribution in Spain. The comparison of the 7 Be activity concentrations mean values indicated a north-south gradient (from 3.1 ± 1.1 mBq/m 3 in Bilbao to 4.0 ± 1.8 mBq/m 3 in Sevilla), even though not statistically significant (as indicated by the t-test). However, the analysis of frequency distributions and temporal evolutions of 7 Be activity concentrations have suggested the presence of two main areas, namely northern (Bilbao and Barcelona) and southern (Sevilla) Spain. The identification and analysis of periods associated with the highest values of 7 Be have allowed studying the different synoptic patterns associated with stratospheric-tropospheric transport (STT). In particular, three episodes (one in the north and two in the south) potentially associated with vigorous STT have been identified and analysed in detail. The results displayed that the omega block configuration, extending either over western Russia and Scandinavia or into the Atlantic Ocean, forced the prevailing jet stream to the northeast and south of Spain respectively with subsequent subsidence. In summer, this blocking configuration at high latitudes was combined with the presence of the Azores high pressure system to the west of Spain, affecting the 7 Be activity concentration recorded in the south. Copyright © 2016. Published by Elsevier Ltd.

  19. A Computational Approach for Probabilistic Analysis of LS-DYNA Water Impact Simulations

    NASA Technical Reports Server (NTRS)

    Horta, Lucas G.; Mason, Brian H.; Lyle, Karen H.

    2010-01-01

    NASA s development of new concepts for the Crew Exploration Vehicle Orion presents many similar challenges to those worked in the sixties during the Apollo program. However, with improved modeling capabilities, new challenges arise. For example, the use of the commercial code LS-DYNA, although widely used and accepted in the technical community, often involves high-dimensional, time consuming, and computationally intensive simulations. Because of the computational cost, these tools are often used to evaluate specific conditions and rarely used for statistical analysis. The challenge is to capture what is learned from a limited number of LS-DYNA simulations to develop models that allow users to conduct interpolation of solutions at a fraction of the computational time. For this problem, response surface models are used to predict the system time responses to a water landing as a function of capsule speed, direction, attitude, water speed, and water direction. Furthermore, these models can also be used to ascertain the adequacy of the design in terms of probability measures. This paper presents a description of the LS-DYNA model, a brief summary of the response surface techniques, the analysis of variance approach used in the sensitivity studies, equations used to estimate impact parameters, results showing conditions that might cause injuries, and concluding remarks.

  20. Least-squares (LS) deconvolution of a series of overlapping cortical auditory evoked potentials: a simulation and experimental study

    NASA Astrophysics Data System (ADS)

    Bardy, Fabrice; Van Dun, Bram; Dillon, Harvey; Cowan, Robert

    2014-08-01

    Objective. To evaluate the viability of disentangling a series of overlapping ‘cortical auditory evoked potentials’ (CAEPs) elicited by different stimuli using least-squares (LS) deconvolution, and to assess the adaptation of CAEPs for different stimulus onset-asynchronies (SOAs). Approach. Optimal aperiodic stimulus sequences were designed by controlling the condition number of matrices associated with the LS deconvolution technique. First, theoretical considerations of LS deconvolution were assessed in simulations in which multiple artificial overlapping responses were recovered. Second, biological CAEPs were recorded in response to continuously repeated stimulus trains containing six different tone-bursts with frequencies 8, 4, 2, 1, 0.5, 0.25 kHz separated by SOAs jittered around 150 (120-185), 250 (220-285) and 650 (620-685) ms. The control condition had a fixed SOA of 1175 ms. In a second condition, using the same SOAs, trains of six stimuli were separated by a silence gap of 1600 ms. Twenty-four adults with normal hearing (<20 dB HL) were assessed. Main results. Results showed disentangling of a series of overlapping responses using LS deconvolution on simulated waveforms as well as on real EEG data. The use of rapid presentation and LS deconvolution did not however, allow the recovered CAEPs to have a higher signal-to-noise ratio than for slowly presented stimuli. The LS deconvolution technique enables the analysis of a series of overlapping responses in EEG. Significance. LS deconvolution is a useful technique for the study of adaptation mechanisms of CAEPs for closely spaced stimuli whose characteristics change from stimulus to stimulus. High-rate presentation is necessary to develop an understanding of how the auditory system encodes natural speech or other intrinsically high-rate stimuli.

  1. 21 CFR 73.3117 - 16,23-Dihydrodinaphtho[2,3-a:2′,3′-i] naphth [2′,3′:6,7] indolo [2,3-c] carbazole-5,10,15,17,22...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false 16,23-Dihydrodinaphtho[2,3-a:2â²,3â²-i] naphth [2â²,3â²:6,7] indolo [2,3-c] carbazole-5,10,15,17,22,24-hexone. 73.3117 Section 73.3117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR...

  2. 21 CFR 73.3117 - 16,23-Dihydrodinaphtho[2,3-a:2′,3′-i] naphth [2′,3′:6,7] indolo [2,3-c] carbazole-5,10,15,17,22...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false 16,23-Dihydrodinaphtho[2,3-a:2â²,3â²-i] naphth [2â²,3â²:6,7] indolo [2,3-c] carbazole-5,10,15,17,22,24-hexone. 73.3117 Section 73.3117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR...

  3. 21 CFR 73.3117 - 16,23-Dihydrodinaphtho[2,3-a:2′,3′-i] naphth [2′,3′:6,7] indolo [2,3-c] carbazole-5,10,15,17,22...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false 16,23-Dihydrodinaphtho[2,3-a:2â²,3â²-i] naphth [2â²,3â²:6,7] indolo [2,3-c] carbazole-5,10,15,17,22,24-hexone. 73.3117 Section 73.3117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR...

  4. 21 CFR 73.3117 - 16,23-Dihydrodinaphtho[2,3-a:2′,3′-i] naphth [2′,3′:6,7] indolo [2,3-c] carbazole-5,10,15,17,22...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false 16,23-Dihydrodinaphtho[2,3-a:2â²,3â²-i] naphth [2â²,3â²:6,7] indolo [2,3-c] carbazole-5,10,15,17,22,24-hexone. 73.3117 Section 73.3117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR...

  5. 21 CFR 73.3117 - 16,23-Dihydrodinaphtho[2,3-a:2′,3′-i] naphth [2′,3′:6,7] indolo [2,3-c] carbazole-5,10,15,17,22...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false 16,23-Dihydrodinaphtho[2,3-a:2â²,3â²-i] naphth [2â²,3â²:6,7] indolo [2,3-c] carbazole-5,10,15,17,22,24-hexone. 73.3117 Section 73.3117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR...

  6. Decon2LS: An open-source software package for automated processing and visualization of high resolution mass spectrometry data

    PubMed Central

    Jaitly, Navdeep; Mayampurath, Anoop; Littlefield, Kyle; Adkins, Joshua N; Anderson, Gordon A; Smith, Richard D

    2009-01-01

    Background Data generated from liquid chromatography coupled to high-resolution mass spectrometry (LC-MS)-based studies of a biological sample can contain large amounts of biologically significant information in the form of proteins, peptides, and metabolites. Interpreting this data involves inferring the masses and abundances of biomolecules injected into the instrument. Because of the inherent complexity of mass spectral patterns produced by these biomolecules, the analysis is significantly enhanced by using visualization capabilities to inspect and confirm results. In this paper we describe Decon2LS, an open-source software package for automated processing and visualization of high-resolution MS data. Drawing extensively on algorithms developed over the last ten years for ICR2LS, Decon2LS packages the algorithms as a rich set of modular, reusable processing classes for performing diverse functions such as reading raw data, routine peak finding, theoretical isotope distribution modelling, and deisotoping. Because the source code is openly available, these functionalities can now be used to build derivative applications in relatively fast manner. In addition, Decon2LS provides an extensive set of visualization tools, such as high performance chart controls. Results With a variety of options that include peak processing, deisotoping, isotope composition, etc, Decon2LS supports processing of multiple raw data formats. Deisotoping can be performed on an individual scan, an individual dataset, or on multiple datasets using batch processing. Other processing options include creating a two dimensional view of mass and liquid chromatography (LC) elution time features, generating spectrum files for tandem MS data, creating total intensity chromatograms, and visualizing theoretical peptide profiles. Application of Decon2LS to deisotope different datasets obtained across different instruments yielded a high number of features that can be used to identify and quantify

  7. Decon2LS: An open-source software package for automated processing and visualization of high resolution mass spectrometry data.

    PubMed

    Jaitly, Navdeep; Mayampurath, Anoop; Littlefield, Kyle; Adkins, Joshua N; Anderson, Gordon A; Smith, Richard D

    2009-03-17

    Data generated from liquid chromatography coupled to high-resolution mass spectrometry (LC-MS)-based studies of a biological sample can contain large amounts of biologically significant information in the form of proteins, peptides, and metabolites. Interpreting this data involves inferring the masses and abundances of biomolecules injected into the instrument. Because of the inherent complexity of mass spectral patterns produced by these biomolecules, the analysis is significantly enhanced by using visualization capabilities to inspect and confirm results. In this paper we describe Decon2LS, an open-source software package for automated processing and visualization of high-resolution MS data. Drawing extensively on algorithms developed over the last ten years for ICR2LS, Decon2LS packages the algorithms as a rich set of modular, reusable processing classes for performing diverse functions such as reading raw data, routine peak finding, theoretical isotope distribution modelling, and deisotoping. Because the source code is openly available, these functionalities can now be used to build derivative applications in relatively fast manner. In addition, Decon2LS provides an extensive set of visualization tools, such as high performance chart controls. With a variety of options that include peak processing, deisotoping, isotope composition, etc, Decon2LS supports processing of multiple raw data formats. Deisotoping can be performed on an individual scan, an individual dataset, or on multiple datasets using batch processing. Other processing options include creating a two dimensional view of mass and liquid chromatography (LC) elution time features, generating spectrum files for tandem MS data, creating total intensity chromatograms, and visualizing theoretical peptide profiles. Application of Decon2LS to deisotope different datasets obtained across different instruments yielded a high number of features that can be used to identify and quantify peptides in the

  8. Impact of the NOx SIP Call on Respiratory Hospitalizations in New York State

    EPA Science Inventory

    Asthma is a serious public health problem in New York State (NYS), affecting 8.4% (370,000) children and 7.6% (more than 1.1 million) adults. Asthma burden in New York's urban areas is consistently higher than the national average, with marked differences in prevalence and seve...

  9. The effect of the sigma-1 receptor selective compound LS-1-137 on the DOI-induced head twitch response in mice.

    PubMed

    Malik, Maninder; Rangel-Barajas, Claudia; Mach, Robert H; Luedtke, Robert R

    2016-09-01

    Several receptor mediated pathways have been shown to modulate the murine head twitch response (HTR). However, the role of sigma receptors in the murine (±)-2,5-dimethoxy-4-iodoamphetamine (DOI)-induced HTR has not been previously investigated. We examined the ability of LS-1-137, a novel sigma-1 vs. sigma-2 receptor selective phenylacetamide, to modulate the DOI-induced HTR in DBA/2J mice. We also assessed the in vivo efficacy of reference sigma-1 receptor antagonists and agonists PRE-084 and PPCC. The effect of the sigma-2 receptor selective antagonist RHM-1-86 was also examined. Rotarod analysis was performed to monitor motor coordination after LS-1-137 administration. Radioligand binding techniques were used to determine the affinity of LS-1-137 at 5-HT2A and 5-HT2C receptors. LS-1-137 and the sigma-1 receptor antagonists haloperidol and BD 1047 were able to attenuate a DOI-induced HTR, indicating that LS-1-137 was acting in vivo as a sigma-1 receptor antagonist. LS-1-137 did not compromise rotarod performance within a dose range capable of attenuating the effects of DOI. Radioligand binding studies indicate that LS-1-137 exhibits low affinity binding at both 5-HT2A and 5-HT2C receptors. Based upon the results from these and our previous studies, LS-1-137 is a neuroprotective agent that attenuates the murine DOI-induced HTR independent of activity at 5-HT2 receptor subtypes, D2-like dopamine receptors, sigma-2 receptors and NMDA receptors. LS-1-137 appears to act as a sigma-1 receptor antagonist to inhibit the DOI-induced HTR. Therefore, the DOI-induced HTR can be used to assess the in vivo efficacy of sigma-1 receptor selective compounds. Copyright © 2016. Published by Elsevier Inc.

  10. 33 CFR 165.162 - Safety Zone: New York Super Boat Race, Hudson River, New York.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Safety Zone: New York Super Boat Race, Hudson River, New York. 165.162 Section 165.162 Navigation and Navigable Waters COAST GUARD... § 165.162 Safety Zone: New York Super Boat Race, Hudson River, New York. (a) Regulated area. The...

  11. Revisiting LS I +61°303 with VLBI astrometry

    NASA Astrophysics Data System (ADS)

    Wu, Y. W.; Torricelli-Ciamponi, G.; Massi, M.; Reid, M. J.; Zhang, B.; Shao, L.; Zheng, X. W.

    2018-03-01

    We conducted multi-epoch Very Long Baseline Array (VLBA) phase-referenced observations of LS I +61°303 in order to study its precessing radio jet. Compared to similar observations in 2006, we find that the observed elliptical trajectory of emission at 8.4 GHz repeats after the 9 yr gap. The accurate alignment of the emission patterns yields a precession period of 26.926 ± 0.005 d, which is consistent with that determined by Lomb-Scargle analysis of the radio light curve. We analytically model the projection on the sky plane of the peak position of a precessing, synchrotron-emitting jet, which traces an elliptical trajectory on the sky. Comparing the simulation with the VLBA astrometry we improve our knowledge of the geometry of the system. We measure the LS I +61°303 absolute proper motion to be -0.150 ± 0.006 mas yr-1 eastward and -0.264 ± 0.006 mas yr-1 northward. Removing Galactic rotation, this reveals a small, <20 km s-1, non-circular motion, which indicates a very low kick velocity when the black hole was formed.

  12. Myristic Acid-Modified DA7R Peptide for Whole-Process Glioma-Targeted Drug Delivery.

    PubMed

    Ying, Man; Wang, Songli; Zhang, Mingfei; Wang, Ruifeng; Zhu, Hangchang; Ruan, Huitong; Ran, Danni; Chai, Zhilan; Wang, Xiaoyi; Lu, Weiyue

    2018-06-13

    The clinical treatment of aggressive glioma has been a great challenge, mainly because of the complexity of the glioma microenvironment and the existence of the blood-brain tumor barrier (BBTB)/blood-brain barrier (BBB), which severely hampers the effective accumulation of most therapeutic agents in the glioma region. Additionally, vasculogenic mimicry (VM), angiogenesis, and glioma stem cells (GSC) in malignant glioma also lead to the failure of clinical therapy. To address the aforementioned issues, a whole-process glioma-targeted drug delivery strategy was proposed. The D A7R peptide has effective BBTB-penetrating and notable glioma-, angiogenesis-, and VM-targeting abilities. Herein, we designed a myristic acid modified D A7R ligand (MC- D A7R), which combines tumor-homing D A7R with BBB-penetrable MC. MC- D A7R was then immobilized to PEGylated liposomes (MC- D A7R-LS) to form a whole-process glioma-targeting system. MC- D A7R-LS exhibited exceptional internalization in glioma, tumor neovascular, and brain capillary endothelial cells. Enhanced BBTB- and BBB-traversing efficiencies were also observed on MC- D A7R-LS. Ex vivo imaging on brain tumors also demonstrated the feasibility of MC- D A7R-LS in intracranial glioma-homing, whereas the immunofluorescence studies demonstrated its GSC and angiogenesis homing. Furthermore, doxorubicin-loaded MC- D A7R-LS accomplished a remarkable therapeutic outcome, as a result of a synergistic improvement on the glioma microenvironment. Our study highlights the potential of the MC-modified D A7R peptide as a great candidate for the whole-process glioma-targeted drug delivery.

  13. Candidate counterparts to the soft gamma-ray flare in the direction of LS I +61 303

    NASA Astrophysics Data System (ADS)

    Muñoz-Arjonilla, A. J.; Martí, J.; Combi, J. A.; Luque-Escamilla, P.; Sánchez-Sutil, J. R.; Zabalza, V.; Paredes, J. M.

    2009-04-01

    Context: A short duration burst reminiscent of a soft gamma-ray repeater/anomalous X-ray pulsar behaviour was detected in the direction of LS I +61 303 by the Swift satellite. While the association with this well known gamma-ray binary is likely, a different origin cannot be excluded. Aims: We explore the error box of this unexpected flaring event and establish the radio, near-infrared and X-ray sources in our search for any peculiar alternative counterpart. Methods: We carried out a combined analysis of archive Very Large Array radio data of LS I +61 303 sensitive to both compact and extended emission. We also reanalysed previous near infrared observations with the 3.5 m telescope of the Centro Astronómico Hispano Alemán and X-ray observations with the Chandra satellite. Results: Our deep radio maps of the LS I +61 303 environment represent a significant advancement on previous work and 16 compact radio sources in the LS I +61 303 vicinity are detected. For some detections, we also identify near infrared and X-ray counterparts. Extended emission features in the field are also detected and confirmed. The possible connection of some of these sources with the observed flaring event is considered. Based on these data, we are unable to claim a clear association between the Swift-BAT flare and any of the sources reported here. However, this study represents the most sophisticated attempt to determine possible alternative counterparts other than LS I +61 303.

  14. Immunomodulatory Effects of Lactobacillus salivarius LS01 and Bifidobacterium breve BR03, Alone and in Combination, on Peripheral Blood Mononuclear Cells of Allergic Asthmatics.

    PubMed

    Drago, Lorenzo; De Vecchi, Elena; Gabrieli, Arianna; De Grandi, Roberta; Toscano, Marco

    2015-07-01

    The aim of this study was to evaluate probiotic characteristics of Lactobacillus salivarius LS01 and Bifidobacterium breve BR03 alone and in combination and their immunomodulatory activity in asthmatic subjects. Subjects affected by allergic asthma were recruited. Initially, LS01 and BR03 were analyzed for their growth compatibility by a broth compatibility assay. To study the antimicrobial activity of probiotic strains, an agar diffusion assay was performed. Finally, cytokine production by peripheral blood mononuclear cells (PBMCs) stimulated with LS01 and BR03 was determined by means of specific quantitative enzyme-linked immunosorbent assay (ELISA). The growth of some clinical pathogens were slightly inhibited by LS01 and LS01-BR03 co-culture supernatant not neutralized to pH 6.5, while only the growth of E. coli and S. aureus was inhibited by the supernatant of LS01 and LS01-BR03 neutralized to pH 6.5. Furthermore, LS01 and BR03 combination was able to decrease the secretion of proinflammatory cytokines by PBMCs, leading to an intense increase in IL-10 production. L. salivarius LS01 and B. breve BR03 showed promising probiotic properties and beneficial immunomodulatory activity that are increased when the 2 strains are used in combination in the same formulation.

  15. New York City pedestrian safety study & action plan

    DOT National Transportation Integrated Search

    2010-08-01

    This landmark study is the most statistically ambitious of its kind ever undertaken by a US city. : The researchers worked to identify the causes, common factors, and geographic distribution of : over 7,000 pedestrian crashes in New York City. These ...

  16. Descriptive epidemiology of chronic hypertension, gestational hypertension, and preeclampsia in New York State, 1995-2004.

    PubMed

    Savitz, David A; Danilack, Valery A; Engel, Stephanie M; Elston, Beth; Lipkind, Heather S

    2014-05-01

    We examined social, demographic, and behavioral predictors of specific forms of hypertensive disorders in pregnancy in New York State. Administrative data on 2.3 million births over the period 1995-2004 were available for New York State, USA, with linkage to birth certificate data for New York City (964,071 births). ICD-9 hospital discharge diagnosis codes were used to assign hypertensive disorders hierarchically as chronic hypertension, chronic hypertension with superimposed preeclampsia, preeclampsia (eclampsia/severe or mild), or gestational hypertension. Sociodemographic and behavioral predictors of these outcomes were examined separately for upstate New York and New York City by calculating adjusted odds ratios. The most commonly diagnosed conditions were preeclampsia (2.57 % of upstate New York births, 3.68 % of New York City births) and gestational hypertension (2.46 % of upstate births, 1.42 % of New York City births). Chronic hypertension was much rarer. Relative to non-Hispanic Whites, Hispanics in New York City and Black women in all regions had markedly increased risks for all hypertensive disorders, whereas Asian women were at consistently decreased risk. Pregnancy-associated conditions decreased markedly with parity and modestly among smokers. A strong positive association was found between pre-pregnancy weight and risk of hypertensive disorders, with slightly weaker associations among Blacks and stronger associations among Asians. While patterns of chronic and pregnancy-induced hypertensive disorders differed, the predictors of gestational hypertension and both mild and severe preeclampsia were similar to one another. The increased risk for Black and some Hispanic women warrants clinical consideration, and the markedly increased risk with greater pre-pregnancy weight suggests an opportunity for primary prevention among all ethnic groups.

  17. 7 CFR 1214.23 - Terminate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE CHRISTMAS TREE PROMOTION, RESEARCH, AND INFORMATION ORDER Christmas Tree Promotion, Research, and Information Order Definitions § 1214.23...

  18. 7 CFR 1214.23 - Terminate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE CHRISTMAS TREE PROMOTION, RESEARCH, AND INFORMATION ORDER Christmas Tree Promotion, Research, and Information Order Definitions § 1214.23...

  19. 7 CFR 1214.23 - Terminate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE CHRISTMAS TREE PROMOTION, RESEARCH, AND INFORMATION ORDER Christmas Tree Promotion, Research, and Information Order Definitions § 1214.23...

  20. 7 CFR 1215.23 - Acceptance.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Popcorn Board § 1215.23...

  1. 7 CFR 1215.23 - Acceptance.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Popcorn Board § 1215.23...

  2. 7 CFR 1215.23 - Acceptance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Popcorn Board § 1215.23...

  3. 7 CFR 1215.23 - Acceptance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Popcorn Board § 1215.23...

  4. 7 CFR 1215.23 - Acceptance.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Popcorn Board § 1215.23...

  5. In vivo self-gated 23 Na MRI at 7 T using an oval-shaped body resonator.

    PubMed

    Platt, Tanja; Umathum, Reiner; Fiedler, Thomas M; Nagel, Armin M; Bitz, Andreas K; Maier, Florian; Bachert, Peter; Ladd, Mark E; Wielpütz, Mark O; Kauczor, Hans-Ulrich; Behl, Nicolas G R

    2018-02-09

    This work faces three challenges of sodium ( 23 Na) torso MRI on the way to quantitative 23 Na MRI: Development of a 23 Na radiofrequency transmit and receive coil covering a large part of the human body in width and length for 23 Na MRI at 7 T; reduction of blurring due to respiration in free-breathing 23 Na MRI using a self-gating approach; and reduction of image noise using a compressed-sensing reconstruction. An oval-shaped birdcage resonator with a large field of view of (400 mm) 3 and a homogeneous transmit and receive field distribution was designed, simulated, and implemented on a 7T MR system. In free-breathing 3-dimensional radial 23 Na MRI (acquisition time ≈ 30 minutes), retrospective respiratory self-gating was applied, which sorts the acquired projections into two respiratory states based on the intrinsic respiration-dependent signal changes. Furthermore, a 3-dimensional dictionary-learning compressed-sensing reconstruction was applied. The developed body coil provided homogeneous radiofrequency excitation (flip angle error of 4.9% in central region of interest of 23 × 13 × 10 cm 3 ) and homogeneous signal reception. The self-gating approach allowed for separation of the full data set into two subsets associated with different respiratory states (inhaled and exhaled), and thereby reduced blurring due to respiration in the separated images. Image noise was markedly reduced by the compressed-sensing algorithm. The presented body coil enables full body width 23 Na MRI with long z-axis coverage at 7 T for the first time. Additionally, the retrospective respiratory self-gating performance is demonstrated for free-breathing lung and abdominal 23 Na MRI in 3 subjects. © 2018 International Society for Magnetic Resonance in Medicine.

  6. Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors

    PubMed Central

    2015-01-01

    Novel substituted 2,3-dihydrobenzofuran-7-carboxamide (DHBF-7-carboxamide) and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide (DHBF-3-one-7-carboxamide) derivatives were synthesized and evaluated as inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1). A structure-based design strategy resulted in lead compound 3 (DHBF-7-carboxamide; IC50 = 9.45 μM). To facilitate synthetically feasible derivatives, an alternative core was designed, DHBF-3-one-7-carboxamide (36, IC50 = 16.2 μM). The electrophilic 2-position of this scaffold was accessible for extended modifications. Substituted benzylidene derivatives at the 2-position were found to be the most potent, with 3′,4′-dihydroxybenzylidene 58 (IC50 = 0.531 μM) showing a 30-fold improvement in potency. Various heterocycles attached at the 4′-hydroxyl/4′-amino of the benzylidene moiety resulted in significant improvement in inhibition of PARP-1 activity (e.g., compounds 66–68, 70, 72, and 73; IC50 values from 0.718 to 0.079 μM). Compound 66 showed selective cytotoxicity in BRCA2-deficient DT40 cells. Crystal structures of three inhibitors (compounds (−)-13c, 59, and 65) bound to a multidomain PARP-1 structure were obtained, providing insights into further development of these inhibitors. PMID:24922587

  7. 77 FR 40874 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... Energy LLC, LS Power Marketing, LLC. Description: Updated Market Power Analysis of LS Power Marketing... Company of New York, Inc. Description: Amendment to RDM target filing to be effective 5/11/ 2012. Filed...

  8. Mutation analysis of the MYO7A and CDH23 genes in Japanese patients with Usher syndrome type 1.

    PubMed

    Nakanishi, Hiroshi; Ohtsubo, Masafumi; Iwasaki, Satoshi; Hotta, Yoshihiro; Takizawa, Yoshinori; Hosono, Katsuhiro; Mizuta, Kunihiro; Mineta, Hiroyuki; Minoshima, Shinsei

    2010-12-01

    Usher syndrome (USH) is an autosomal recessive disorder characterized by retinitis pigmentosa and hearing loss. USH type 1 (USH1), the second common type of USH, is frequently caused by MYO7A and CDH23 mutations, accounting for 70-80% of the cases among various ethnicities, including Caucasians, Africans and Asians. However, there have been no reports of mutation analysis for any responsible genes for USH1 in Japanese patients. This study describes the first mutation analysis of MYO7A and CDH23 in Japanese USH1 patients. Five mutations (three in MYO7A and two in CDH23) were identified in four of five unrelated patients. Of these mutations, two were novel. One of them, p.Tyr1942SerfsX23 in CDH23, was a large deletion causing the loss of 3 exons. This is the first large deletion to be found in CDH23. The incidence of the MYO7A and CDH23 mutations in the study population was 80%, which is consistent with previous findings. Therefore, mutation screening for these genes is expected to be a highly sensitive method for diagnosing USH1 among the Japanese.

  9. 77 FR 42507 - Notice of Inventory Completion: New York University College of Dentistry, New York, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... Inventory Completion: New York University College of Dentistry, New York, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The New York University College of Dentistry has completed an inventory... the New York University College of Dentistry. Disposition of the human remains to the Indian tribes...

  10. 77 FR 42513 - Notice of Inventory Completion: New York University College of Dentistry, New York, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... Inventory Completion: New York University College of Dentistry, New York, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The New York University College of Dentistry has completed an inventory... the New York University College of Dentistry. Disposition of the human remains to the Indian tribes...

  11. 77 FR 42508 - Notice of Inventory Completion: New York University College of Dentistry, New York, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... Inventory Completion: New York University College of Dentistry, New York, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The New York University College of Dentistry has completed an inventory... the New York University College of Dentistry. Repatriation of the human remains to the Indian tribes...

  12. The intellectual capacity of patients with Laron syndrome (LS) differs with various molecular defects of the growth hormone receptor gene. Correlation with CNS abnormalities.

    PubMed

    Shevah, O; Kornreich, L; Galatzer, A; Laron, Z

    2005-12-01

    The correlation between the molecular defects of the GH receptor (R), psychosocial development and brain abnormalities were evaluated in 10 patients with Laron syndrome (LS), in whom all data were available. The findings revealed that the intelligence quotient (IQ) and abnormalities in the brain of the patients with LS differ with various molecular defects of the GH-receptor. The most severe mental deficits and brain pathology occurred in patients with 3, 5, 6 exon deletion. Patients with point mutations in exons 2, 4 and 7 presented various degrees of medium to mild CNS abnormalities that correlated with the IQ. Notably, the patient with the E180 splice mutation in exon 6 had a normal IQ, which fits the report on normal IQ in a large Ecuadorian cohort with the same mutation. This is the first report to support a correlation between IQ, brain abnormalities and localization of the molecular defects in the GH-R gene. As all patients with LS are IGF-I-deficient, it must be assumed that other as yet unknown factors related to the molecular defects in the GH-R are the major cause of the differences in intellect and brain abnormalities.

  13. Monte Carlo uncertainty analyses of a bLS inverse-dispersion technique for measuring gas emissions from livestock operations

    USDA-ARS?s Scientific Manuscript database

    The backward Lagrangian stochastic (bLS) inverse-dispersion technique has been used to measure fugitive gas emissions from livestock operations. The accuracy of the bLS technique, as indicated by the percentages of gas recovery in various tracer-release experiments, has generally been within ± 10% o...

  14. High-energy emissions from the gamma-ray binary LS 5039

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Takata, J.; Leung, Gene C. K.; Cheng, K. S.

    2014-07-20

    We study mechanisms of multi-wavelength emissions (X-ray, GeV, and TeV gamma-rays) from the gamma-ray binary LS 5039. This paper is composed of two parts. In the first part, we report on results of observational analysis using 4 yr data of the Fermi Large Area Telescope. Due to the improvement of instrumental response function and increase of the statistics, the observational uncertainties of the spectrum in the ∼100-300 MeV bands and >10 GeV bands are significantly improved. The present data analysis suggests that the 0.1-100 GeV emissions from LS 5039 contain three different components: (1) the first component contributes to <1more » GeV emissions around superior conjunction, (2) the second component dominates in the 1-10 GeV energy bands, and (3) the third component is compatible with the lower-energy tail of the TeV emissions. In the second part, we develop an emission model to explain the properties of the phase-resolved emissions in multi-wavelength observations. Assuming that LS 5039 includes a pulsar, we argue that emissions from both the magnetospheric outer gap and the inverse-Compton scattering process of cold-relativistic pulsar wind contribute to the observed GeV emissions. We assume that the pulsar is wrapped by two kinds of termination shock: Shock-I due to the interaction between the pulsar wind and the stellar wind and Shock-II due to the effect of the orbital motion. We propose that the X-rays are produced by the synchrotron radiation at the Shock-I region and the TeV gamma-rays are produced by the inverse-Compton scattering process at the Shock-II region.« less

  15. STS-36 night Earth observation of New York City, New York

    NASA Image and Video Library

    1990-03-03

    STS-36 Earth observation shows New York City, New York at night lit up along the Eastern seaboard of the United States and the Atlantic Ocean. The city lights designate the densely populated central city and the major highways surrounding it.

  16. A new Em-like protein from Lactuca sativa, LsEm1, enhances drought and salt stress tolerance in Escherichia coli and rice.

    PubMed

    Xiang, Dian-Jun; Man, Li-Li; Zhang, Chun-Lan; Peng-Liu; Li, Zhi-Gang; Zheng, Gen-Chang

    2018-02-07

    Late embryogenesis abundant (LEA) proteins are closely related to abiotic stress tolerance of plants. In the present study, we identified a novel Em-like gene from lettuce, termed LsEm1, which could be classified into group 1 LEA proteins, and shared high homology with Cynara cardunculus Em protein. The LsEm1 protein contained three different 20-mer conserved elements (C-element, N-element, and M-element) in the C-termini, N-termini, and middle-region, respectively. The LsEm1 mRNAs were accumulated in all examined tissues during the flowering and mature stages, with a little accumulation in the roots and leaves during the seedling stage. Furthermore, the LsEm1 gene was also expressed in response to salt, dehydration, abscisic acid (ABA), and cold stresses in young seedlings. The LsEm1 protein could effectively reduce damage to the lactate dehydrogenase (LDH) and protect LDH activity under desiccation and salt treatments. The Escherichia coli cells overexpressing the LsEm1 gene showed a growth advantage over the control under drought and salt stresses. Moreover, LsEm1-overexpressing rice seeds were relatively sensitive to exogenously applied ABA, suggesting that the LsEm1 gene might depend on an ABA signaling pathway in response to environmental stresses. The transgenic rice plants overexpressing the LsEm1 gene showed higher tolerance to drought and salt stresses than did wild-type (WT) plants on the basis of the germination performances, higher survival rates, higher chlorophyll content, more accumulation of soluble sugar, lower relative electrolyte leakage, and higher superoxide dismutase activity under stress conditions. The LsEm1-overexpressing rice lines also showed less yield loss compared with WT rice under stress conditions. Furthermore, the LsEm1 gene had a positive effect on the expression of the OsCDPK9, OsCDPK13, OsCDPK15, OsCDPK25, and rab21 (rab16a) genes in transgenic rice under drought and salt stress conditions, implying that overexpression of these

  17. 7 CFR 29.23 - Tobacco.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... INSPECTION Regulations Definitions § 29.23 Tobacco. Tobacco in its unmanufactured forms as it appears between... manufacturing process. Conditioning, sweating, and stemming are not regarded as manufacturing processes. ...

  18. 7 CFR 29.23 - Tobacco.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... INSPECTION Regulations Definitions § 29.23 Tobacco. Tobacco in its unmanufactured forms as it appears between... manufacturing process. Conditioning, sweating, and stemming are not regarded as manufacturing processes. ...

  19. 7 CFR 29.23 - Tobacco.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... INSPECTION Regulations Definitions § 29.23 Tobacco. Tobacco in its unmanufactured forms as it appears between... manufacturing process. Conditioning, sweating, and stemming are not regarded as manufacturing processes. ...

  20. 7 CFR 29.23 - Tobacco.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INSPECTION Regulations Definitions § 29.23 Tobacco. Tobacco in its unmanufactured forms as it appears between... manufacturing process. Conditioning, sweating, and stemming are not regarded as manufacturing processes. ...

  1. 7 CFR 29.23 - Tobacco.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... INSPECTION Regulations Definitions § 29.23 Tobacco. Tobacco in its unmanufactured forms as it appears between... manufacturing process. Conditioning, sweating, and stemming are not regarded as manufacturing processes. ...

  2. 7 CFR 983.23 - Processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE PISTACHIOS GROWN IN CALIFORNIA, ARIZONA, AND NEW MEXICO Definitions § 983.23 Processing. Processing means hulling and drying pistachios in...

  3. Novel Hybrid of LS-SVM and Kalman Filter for GPS/INS Integration

    NASA Astrophysics Data System (ADS)

    Xu, Zhenkai; Li, Yong; Rizos, Chris; Xu, Xiaosu

    Integration of Global Positioning System (GPS) and Inertial Navigation System (INS) technologies can overcome the drawbacks of the individual systems. One of the advantages is that the integrated solution can provide continuous navigation capability even during GPS outages. However, bridging the GPS outages is still a challenge when Micro-Electro-Mechanical System (MEMS) inertial sensors are used. Methods being currently explored by the research community include applying vehicle motion constraints, optimal smoother, and artificial intelligence (AI) techniques. In the research area of AI, the neural network (NN) approach has been extensively utilised up to the present. In an NN-based integrated system, a Kalman filter (KF) estimates position, velocity and attitude errors, as well as the inertial sensor errors, to output navigation solutions while GPS signals are available. At the same time, an NN is trained to map the vehicle dynamics with corresponding KF states, and to correct INS measurements when GPS measurements are unavailable. To achieve good performance it is critical to select suitable quality and an optimal number of samples for the NN. This is sometimes too rigorous a requirement which limits real world application of NN-based methods.The support vector machine (SVM) approach is based on the structural risk minimisation principle, instead of the minimised empirical error principle that is commonly implemented in an NN. The SVM can avoid local minimisation and over-fitting problems in an NN, and therefore potentially can achieve a higher level of global performance. This paper focuses on the least squares support vector machine (LS-SVM), which can solve highly nonlinear and noisy black-box modelling problems. This paper explores the application of the LS-SVM to aid the GPS/INS integrated system, especially during GPS outages. The paper describes the principles of the LS-SVM and of the KF hybrid method, and introduces the LS-SVM regression algorithm. Field

  4. 75 FR 33329 - Notice of Inventory Completion: New York University College of Dentistry, New York, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... University College of Dentistry, New York, NY AGENCY: National Park Service, Interior. ACTION: Notice. Notice... the New York University College of Dentistry, New York, NY. The human remains were removed from.... A detailed assessment of the human remains was made by the New York University College of Dentistry...

  5. A MAGNETAR-LIKE EVENT FROM LS I +61 Degree-Sign 303 AND ITS NATURE AS A GAMMA-RAY BINARY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Torres, Diego F.; Rea, Nanda; Esposito, Paolo

    2012-01-10

    We report on the Swift Burst Alert Telescope detection of a short burst from the direction of the TeV binary LS I +61 Degree-Sign 303, resembling those generally labeled as magnetar-like. We show that it is likely that the short burst was indeed originating from LS I +61 Degree-Sign 303 (although we cannot totally exclude the improbable presence of a far-away, line-of-sight magnetar) and that it is a different phenomenon with respect to the previously observed ks-long flares from this system. Accepting the hypothesis that LS I +61 Degree-Sign 303 is the first magnetar detected in a binary system, wemore » study those implications. We find that a magnetar-composed LS I +61 Degree-Sign 303 system would most likely be (i.e., for the usual magnetar parameters and mass-loss rate) subject to a flip-flop behavior, from a rotationally powered regime (in the apastron) to a propeller regime (in the periastron) along each of the LS I +61 Degree-Sign 303 eccentric orbital motion. We prove that, unlike near an apastron, where an interwind shock can lead to the normally observed LS I +61 Degree-Sign 303 behavior, during TeV emission the periastron propeller is expected to efficiently accelerate particles only to sub-TeV energies. This flip-flop scenario would explain the system's behavior when a recurrent TeV emission only appears near the apastron, the anti-correlation of the GeV and TeV emission, and the long-term TeV variability (which seems correlated to LS I +61 Degree-Sign 303's super-orbital period), including the appearance of a low TeV state. Finally, we qualitatively put the multi-wavelength phenomenology into the context of our proposed model and make some predictions for further testing.« less

  6. Seventh/Eighth Grade Social Studies. United States and New York State History. A Calendar of Lessons.

    ERIC Educational Resources Information Center

    Bromberg, Lloyd; And Others

    This calendar of lessons conforms to the New York State syllabus for grades 7-8, United States and New York History, which was officially implemented throughout the state in September 1987. It is a guide to the objectives of the state social studies program, not a prescription for day-to-day lesson plans. United States and New York State History…

  7. 7 CFR 220.23 - Nutrition standards and menu planning approaches for breakfasts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Nutrition standards and menu planning approaches for... AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.23 Nutrition standards and menu planning approaches for breakfasts. (a) What are the nutrition...

  8. 7 CFR 220.23 - Nutrition standards and menu planning approaches for breakfasts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Nutrition standards and menu planning approaches for... AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.23 Nutrition standards and menu planning approaches for breakfasts. (a) What are the nutrition...

  9. Measurements of radon and thoron progeny concentrations in dwellings of Tehri Garhwal, India, using LR-115 deposition-based DTPS/DRPS technique.

    PubMed

    Prasad, Mukesh; Rawat, Mukesh; Dangwal, Anoop; Yadav, Manjulata; Gusain, G S; Mishra, Rosaline; Ramola, R C

    2015-11-01

    This paper presents the values of radon and thoron progeny concentrations for different seasons in the dwellings of Tehri Garhwal, India. The measurements have been carried out using LR-115 solid-state nuclear track detector-based passive time-integrated direct thoron progeny sensor/direct radon progeny sensor technique. In summer, the radon and thoron progeny have been found to vary from 5.7±0.8 to 153.2±4.3 Bq m(-3) with an average of 37.6 Bq m(-3) and 0.3±0.06 to 3.2±0.19 Bq m(-3) with an average of 1.3 Bq m(-3), respectively. In the rainy season, the radon and thoron progeny have been found to vary from 3.2±0.6 to 120±3.7 Bq m(-3) with an average of 58.2 Bq m(-3) and 0.2±0.05 to 11.3±0.37 Bq m(-3) with an average of 3.4 Bq m(-3), respectively. In autumn, the radon and thoron progeny have been found to vary from 4.1±0.7 to 374.4±6.7 Bq m(-3) with an average of 95.6 Bq m(-3) and from 0.3±0.06 to 30.5±0.60 Bq m(-3) with an average of 6.6 Bq m(-3), respectively. In winter, the radon and thoron progeny have been found to vary from 9.8±1.1 to 188.9±4.8 Bq m(-3) with an average of 70.7 Bq m(-3) and 0.1±0.03 to 7.5±0.30 Bq m(-3) with an average of 2.3 Bq m(-3), respectively. It has been observed that the average value of radon and thoron progeny concentrations is maximum for autumn and minimum for summer seasons. The seasonal variations in radon and thoron progeny concentrations in different houses are discussed in detail. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. 33 CFR 117.799 - Long Island, New York Inland Waterway from East Rockaway Inlet to Shinnecock Canal.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Parkway bridge, mile 30.7 across State Boat Channel at Captree Island, shall open on signal if at least... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Long Island, New York Inland... Requirements New York § 117.799 Long Island, New York Inland Waterway from East Rockaway Inlet to Shinnecock...

  11. 33 CFR 117.799 - Long Island, New York Inland Waterway from East Rockaway Inlet to Shinnecock Canal.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Parkway bridge, mile 30.7 across State Boat Channel at Captree Island, shall open on signal if at least... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Long Island, New York Inland... Requirements New York § 117.799 Long Island, New York Inland Waterway from East Rockaway Inlet to Shinnecock...

  12. 33 CFR 117.799 - Long Island, New York Inland Waterway from East Rockaway Inlet to Shinnecock Canal.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Parkway bridge, mile 30.7 across State Boat Channel at Captree Island, shall open on signal if at least... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Long Island, New York Inland... Requirements New York § 117.799 Long Island, New York Inland Waterway from East Rockaway Inlet to Shinnecock...

  13. Transport of the radioisotopes iodine-131, cesium-134, and cesium-137 from the fallout following the accident at the Chernobyl nuclear reactor into cheesemaking products.

    PubMed

    Assimakopoulos, P A; Ioannides, K G; Pakou, A A; Papadopoulou, C V; Paradopoulou, C V

    1987-07-01

    The transport of radiation contamination from milk to products of the cheese making process has been studied. The concentration of radioactive iodine and cesium in samples of sheep milk and cheese (Gruyère) products was measured for 10 consecutive production d. Milk with concentration 100 Bq/L in each of the radionuclides 131I, 134Cs, and 137Cs cheese with concentration 82.2 +/- 3.9 Bq/kg in iodine and an average of 42.3 +/- 2.3 Bq/kg in the cesium isotopes is produced. The corresponding concentrations in cream extracted from the same milk are 26.7 +/- 2.8 Bq/kg (131I) and 18.6 +/- 1.9 Bq/kg (134Cs, 137Cs).

  14. Effective collision strengths for forbidden transitions among the 3s23p3 fine-structure levels of CL IIIIII

    NASA Astrophysics Data System (ADS)

    Ramsbottom, C. A.; Bell, K. L.; Keenan, F. P.

    1999-08-01

    Effective collision strengths for the 10 astrophysically important fine-structure forbidden transitions among the ^4S^o, ^2D^o and ^2P^o levels in the 3s^23p^3 configuration of Cliii are presented. The calculation employs the multichannel R-matrix method to compute the electron-impact excitation collision strengths in a close-coupling expansion, which incorporates the lowest 23 LS target eigenstates of Cliii. These states are formed from the 3s^23p^3, 3s3p^4, 3s^23p^23d and 3s^23p^24s configurations. The Maxwellian-averaged effective collision strengths are presented graphically for all 10 fine-structure transitions over a wide range of electron temperatures appropriate for astrophysical applications [logT(K)=3.3-logT(K)=5.9]. Comparisons are made with the earlier seven-state close-coupling calculation of Butler & Zeippen, and in general excellent agreement is found in the low-temperature region where a comparison is possible [logT(K)=3.3-logT(K)=4.7]. However, discrepancies of up to 30 per cent are found to occur for the forbidden transitions which involve the ^4S^o ground state level, particularly for the lowest temperatures considered. At the higher temperatures, the present data are the only reliable results currently available.

  15. Mobility of the native Bacillus subtilis conjugative plasmid pLS20 is regulated by intercellular signaling.

    PubMed

    Singh, Praveen K; Ramachandran, Gayetri; Ramos-Ruiz, Ricardo; Peiró-Pastor, Ramón; Abia, David; Wu, Ling J; Meijer, Wilfried J J

    2013-10-01

    Horizontal gene transfer mediated by plasmid conjugation plays a significant role in the evolution of bacterial species, as well as in the dissemination of antibiotic resistance and pathogenicity determinants. Characterization of their regulation is important for gaining insights into these features. Relatively little is known about how conjugation of Gram-positive plasmids is regulated. We have characterized conjugation of the native Bacillus subtilis plasmid pLS20. Contrary to the enterococcal plasmids, conjugation of pLS20 is not activated by recipient-produced pheromones but by pLS20-encoded proteins that regulate expression of the conjugation genes. We show that conjugation is kept in the default "OFF" state and identified the master repressor responsible for this. Activation of the conjugation genes requires relief of repression, which is mediated by an anti-repressor that belongs to the Rap family of proteins. Using both RNA sequencing methodology and genetic approaches, we have determined the regulatory effects of the repressor and anti-repressor on expression of the pLS20 genes. We also show that the activity of the anti-repressor is in turn regulated by an intercellular signaling peptide. Ultimately, this peptide dictates the timing of conjugation. The implications of this regulatory mechanism and comparison with other mobile systems are discussed.

  16. Tetrachloroethylene (PCE, Perc) levels in residential dry cleaner buildings in diverse communities in New York City.

    PubMed

    McDermott, Michael J; Mazor, Kimberly A; Shost, Stephen J; Narang, Rajinder S; Aldous, Kenneth M; Storm, Jan E

    2005-10-01

    Fugitive tetrachloroethylene (PCE, perc) emissions from dry cleaners operating in apartment buildings can contaminate residential indoor air. In 1997, New York State and New York City adopted regulations to reduce and contain perc emissions from dry cleaners located in residential and other buildings. As part of a New York State Department of Health (NYSDOH) study, indoor air perc levels were determined in 65 apartments located in 24 buildings in New York City where dry cleaners used perc on site. Sampling occurred during 2001-2003, and sampled buildings were dispersed across minority and nonminority as well as low-income and higher income neighborhoods. For the entire study area, the mean apartment perc level was 34 microg/m3, 10-fold lower than mean apartment levels of 340-360 microg/m3 documented before 1997. The maximum detected perc level was 5,000 microg/m3, 5-fold lower than the maximum of 25,000 microg/m3 documented before 1997. Despite these accomplishments, perc levels in 17 sampled apartments still exceeded the NYSDOH residential air guideline of 100 microg/m3, and perc levels in 4 sampled apartments exceeded 1,000 microg/m3. Moreover, mean indoor air perc levels in minority neighborhoods (75 microg/m3) were four times higher than in nonminority households (19 microg/m3) and were > 10 times higher in low-income neighborhoods (256 microg/m3) than in higher income neighborhoods (23 microg/m3). Logistic regression suitable for clustered data (apartments within buildings) indicated that perc levels on floors 1-4 were significantly more likely to exceed 100 microg/m3 in buildings located in minority neighborhoods (odds ratio = 6.7; 95% confidence interval, 1.5-30.5) than in nonminority neighborhoods. Factors that may be contributing to the elevated perc levels detected, especially in minority and low-income neighborhoods, are being explored.

  17. Estimating the Hospital Delivery Costs Associated With Severe Maternal Morbidity in New York City, 2008-2012.

    PubMed

    Howland, Renata E; Angley, Meghan; Won, Sang Hee; Wilcox, Wendy; Searing, Hannah; Tsao, Tsu-Yu

    2018-02-01

    To quantify the average and total hospital delivery costs associated with severe maternal morbidity in excess of nonsevere maternal morbidity deliveries over a 5-year period in New York City adjusting for other sociodemographic and clinical factors. We conducted a population-based cross-sectional study using linked birth certificates and hospital discharge data for New York City deliveries from 2008 to 2012. Severe maternal morbidity was defined using a published algorithm of International Classification of Diseases, 9 Revision, Clinical Modification disease and procedure codes. Hospital costs were estimated by converting hospital charges using factors specific to each year and hospital and to each diagnosis. These estimates approximate what it costs the hospital to provide services (excluding professional fees) and were used in all subsequent analyses. To estimate adjusted mean costs associated with severe maternal morbidity, we used multivariable regression models with a log link, gamma distribution, robust standard errors, and hospital fixed effects, controlling for age, race and ethnicity, neighborhood poverty, primary payer, number of deliveries, method of delivery, comorbidities, and year. We used the adjusted mean cost to determine the average and total hospital delivery costs associated with severe maternal morbidity in excess of nonsevere maternal morbidity deliveries from 2008 to 2012. Approximately 2.3% (n=13,502) of all New York City delivery hospitalizations were complicated by severe maternal morbidity. Compared with nonsevere maternal morbidity deliveries, these hospitalizations were clinically complicated, required more and intensive clinical services, and had a longer stay in the hospital. The average cost of delivery with severe maternal morbidity was $14,442 (95% CI $14,128-14,756), compared with $7,289 (95% CI $7,276-7,302) among deliveries without severe maternal morbidity. After adjusting for other factors, the difference between deliveries

  18. The primary structure of aspartate aminotransferase from pig heart muscle. Digestion with a proteinase having specificity for lysine residues.

    PubMed Central

    Doonan, S; Doonan, H J; Hanford, R; Vernon, C A; Walker, J M; da Airold, L P; Bossa, F; Barra, D; Carloni, M; Fasella, P; Riva, F

    1975-01-01

    Carboxymethylated aspartate aminotransferase was digested with a proteinase claimed to be specific for lysine residues. Complete cleavage occurred at 12 of the 19 lysine residues in the protein, but at the remaining seven residues cleavage was either restricted or absent. In addition, cleavage was observed at three of the 26 arginine residues. These results are discussed with reference to the amino acid residues adjacent to points of complete or restricted cleavage. The complete primary structure of aspartate aminotransferase, based on these and other studies, is given. Evidence for the assignment of some acid and amide side chains has been deposited as Supplementary Publication SUP 50050 (11 pp.) at the British Library (Lending Division), Boston Spa, Wetherby, W. Yorkshire LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1975) 145, 5. The evidence for the assignment of residue 366 was less conclusive than for the other acid and amide side chains and is, therefore, given in the main paper. PMID:1239277

  19. Cost estimates for flood resilience and protection strategies in New York City.

    PubMed

    Aerts, Jeroen C J H; Botzen, W J Wouter; de Moel, Hans; Bowman, Malcolm

    2013-08-01

    In the aftermaths of Hurricanes Irene, in 2011, and Sandy, in 2012, New York City has come to recognize the critical need to better prepare for future storm surges and to anticipate future trends, such as climate change and socio-economic developments. The research presented in this report assesses the costs of six different flood management strategies to anticipate long-term challenges the City will face. The proposed strategies vary from increasing resilience by upgrading building codes and introducing small scale protection measures, to creating green infrastructure as buffer zones and large protective engineering works such as storm surge barriers. The initial investment costs of alternative strategies vary between $11.6 and $23.8 bn, maximally. We show that a hybrid solution, combining protection of critical infrastructure and resilience measures that can be upgraded over time, is less expensive. However, with increasing risk in the future, storm surge barriers may become cost-effective, as they can provide protection to the largest areas in both New York and New Jersey. © 2013 New York Academy of Sciences.

  20. Multi-scale Material Parameter Identification Using LS-DYNA® and LS-OPT®

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stander, Nielen; Basudhar, Anirban; Basu, Ushnish

    2015-09-14

    Comprehensive Test Ban Treaty of 1996 which banned surface testing of nuclear devices [1]. This had the effect that experimental work was reduced from large scale tests to multiscale experiments to provide material models with validation at different length scales. In the subsequent years industry realized that multi-scale modeling and simulation-based design were transferable to the design optimization of any structural system. Horstemeyer [1] lists a number of advantages of the use of multiscale modeling. Among these are: the reduction of product development time by alleviating costly trial-and-error iterations as well as the reduction of product costs through innovations in material, product and process designs. Multi-scale modeling can reduce the number of costly large scale experiments and can increase product quality by providing more accurate predictions. Research tends to be focussed on each particular length scale, which enhances accuracy in the long term. This paper serves as an introduction to the LS-OPT and LS-DYNA methodology for multi-scale modeling. It mainly focuses on an approach to integrate material identification using material models of different length scales. As an example, a multi-scale material identification strategy, consisting of a Crystal Plasticity (CP) material model and a homogenized State Variable (SV) model, is discussed and the parameter identification of the individual material models of different length scales is demonstrated. The paper concludes with thoughts on integrating the multi-scale methodology into the overall vehicle design.« less

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