Song, S; Oh, S; Lim, K-T
2015-06-01
Lactobacilli in the human gastrointestinal tract have beneficial effects on the health of their host. To enhance these effects, the bioactivity of lactobacilli can be fortified through exogenous dietary or pharmacological agents, such as glycoproteins. To elucidate the inductive effect of Zanthoxylum piperitum DC (ZPDC) glycoprotein on Lactobacillus plantarum L67, we evaluated the radical-scavenging activity, anti-oxidative enzymes (SOD, GPx and CAT), growth rate, ATPase activity and β-galactosidase activity of this strain. When Lact. plantarum L67 was treated with ZPDC glycoprotein at different concentrations, the intensities of a few SDS-PAGE bands were slightly changed. The amount of a 23 kDa protein was increased upon treatment with increasing concentrations of ZPDC glycoprotein. The results of this study indicate that the radical-scavenging activity for O2(-) and OH¯, but not for the DPPH radical, increased in a concentration-dependent manner after treatment with ZPDC glycoprotein. The activation of anti-oxidative enzymes (SOD, GPx and CAT), growth rate and β-galactosidase activity also increased in a concentration-dependent manner in response to ZPDC glycoprotein treatment, whereas ATPase activity was decreased. In summary, ZPDC glycoprotein stimulated an increase in the bioactivity of Lact. plantarum L67. Significance and impact of the study: This study demonstrated that Lactobacillus plantarum L67 possesses anti-oxidative activity. This strain of lactic bacteria has been known to have various probiotic uses, such as yogurt starters and dietary additional supplements. We found, through this experiment, that the protein has a strong anti-oxidative character, and the activity can be enhanced by treatment with Zanthoxylum piperitum DC (ZPDC) glycoprotein. This study may be application of Lact. plantarum L67 treated by ZPDC glycoprotein in yogurt fermentation. It could be one of the avenues of minimizing yogurt postacidification during storage. In addition
Gwon, So Young; Ahn, Ji Yun; Kim, Tae Wan; Ha, Tae Youl
2012-01-01
This study was conducted to determine the anti-obesity effects of Zanthoxylum piperitum DC fruit ethanol extract (ZPE) in 3T3-L1 adipocytes and obese mice fed a high-fat diet. We evaluated the influence of the addition of ZPE to a high-fat diet on body weight, adipose tissue weight, serum and hepatic lipids in C57BL/6 mice. In addition, adipogenic gene expression was determined by Western blot and real-time reverse transcription-PCR analysis. We assessed the effect of ZPE on 3T3-L1 preadipocyte differentiation. ZPE reduced weight gain, white adipose tissue mass, and serum triglyceride and cholesterol levels (p<0.05) in high-fat diet-fed C57BL/6 mice. ZPE decreased lipid accumulation and PPARγ, C/EBPα, SREBP-1, and FAS protein and mRNA levels in the liver. ZPE inhibited in vitro adipocyte differentiation in a dose-dependent manner and significantly attenuated adipogenic transcription factors, such as PPARγ, C/EBPα, and SREBP-1 in 3T3L1 cells. These findings suggest that Z. piperitum DC exerts an anti-obesity effect by inhibiting adipogenesis through the downregulation of genes involved in the adipogenesis pathway.
Yang, Seo Young; Lee, Sang-Hyun; Tai, Bui Huu; Jang, Hae-Dong; Kim, Young Ho
2018-02-18
Two new lignans, zanthoxyloside C ( 1 ) and zanthoxyloside D ( 2 ), together with nine known compounds comprising lignans ( 3 - 5 ), flavonoids ( 6 - 8 ), and phenolics ( 9 - 11 ), were isolated from the methanol extract of the stems of Zanthoxylum piperitum. All isolates were evaluated for their antioxidant and anti-osteoporotic activities using oxygen radical absorbance capacity (ORAC), cupric reducing antioxidant capacity (CUPRAC), and tartrate-resistant acid phosphatase (TRAP) assays. Compounds 7 - 10 showed peroxyl radical-scavenging capacities and 4 , 6 - 7 , and 9 showed reducing capacities. Moreover, compounds 3 , 6 - 9 , and 11 significantly suppressed TRAP activities. These results indicated that the stems of Z. piperitum could be an excellent source for natural antioxidant and anti-osteoporosis.
Kim, Soon-Il; Ahn, Young-Joon
2017-05-04
The yellow fever mosquito, Aedes aegypti, and the common house mosquito, Culex pipiens pallens, transmit dengue fever and West Nile virus diseases, respectively. This study was conducted to determine the toxicity of the three lignans (-)-asarinin, sesamin and (+)-xanthoxylol-γ,γ-dimethylallylether (XDA), and the alkaloid pellitorine from Zanthoxylum piperitum (Rutaceae) bark to third-instar larvae from insecticide-susceptible C. pipiens pallens and Ae. aegypti as well as wild C. pipiens pallens resistant to deltamethrin, cyfluthrin, fenthion, and temephos. The toxicities of all isolates were compared with those of mosquito larvicide temephos. LC 50 values for each species and their treatments were significantly different from one another when their 95% confidence intervals did not overlap. XDA was isolated from Z. piperitum as a new larvicidal principle. XDA (LC 50 , 0.27 and 0.24 mg/l) was 4, 53, and 144 times and 4, 100, and 117 times more toxic than pellitorine, sesamin, and asarinin toward larvae from susceptible C. pipiens pallens and Ae. aegypti, respectively. Overall, all the isolates were less toxic than temephos (LC 50 , 0.006 and 0.009 mg/l). These constituents did not differ in toxicity to larvae from the two Culex strains. The present finding indicates that the lignans and alkaloid and the insecticides do not share a common mode of larvicidal action or elicit cross-resistance. Naturally occurring Z. piperitum bark-derived compounds, particularly XDA, merit further study as potential mosquito larval control agents or as lead compounds for the control of insecticide-resistant mosquito populations.
Frerot, Eric; Neirynck, Nathalie; Cayeux, Isabelle; Yuan, Yoyo Hui-Juan; Yuan, Yong-Ming
2015-08-19
A series of aromatic amides were synthesized from various acids and amines selected from naturally occurring structural frameworks. These synthetic amides were evaluated for umami taste in comparison with monosodium glutamate. The effect of the substitution pattern of both the acid and the amine parts on umami taste was investigated. The only intensely umami-tasting amides were those made from 3,4-dimethoxycinnamic acid. The amine part was more tolerant to structural changes. Amides bearing an alkyl- or alkoxy-substituted phenylethylamine residue displayed a clean umami taste as 20 ppm solutions in water. Ultraperformance liquid chromatography coupled with a high quadrupole-Orbitrap mass spectrometer (UPLC/MS) was subsequently used to show the natural occurrence of these amides. (E)-3-(3,4-Dimethoxyphenyl)-N-(4-methoxyphenethyl)acrylamide was shown to occur in the roots and stems of Zanthoxylum piperitum, a plant of the family Rutaceae growing in Korea, Japan, and China.
Kim, Mi Hye; Lee, Hye Ji; Park, Jung-Chul; Hong, Jongki; Yang, Woong Mo
2017-01-04
Zanthoxylum piperitum (ZP) has been used to prevent toothache in East Asia. In this study, we investigated the effects of ZP on periodontitis along with alveolar bone loss. Twenty-eight male Sprague-Dawley rats were assigned into 4 groups; non-ligated (NOR), ligated and treated vehicle (CTR), ligated and treated 1mg/mL ZP (ZP1), and ligated and treated 100mg/mL ZP (ZP100). Sterilized 3-0 nylon ligature was placed into the subgingival sulcus around the both sides of mandibular first molar. After topical application of 1 and 100mg/mL ZP for 2 weeks, mandibles was removed for histology. In addition, SaOS-2 osteoblast cells were treated 1, 10 and 100μg/mL ZP for 24h to analyze the expressions of alveolar bone-related markers. Several alveolar bone resorption pits, which indicate cementum demineralization were decreased by ZP treatment. Topical ZP treatment inhibited periodontitis-induced alveolar bone loss. In addition, there were significant reduction of osteoclastic activities following topical ZP treatment in periodontium. The expression of RANKL was decreased in SaOS-2 osteoblast cells by treating ZP, while that of OPG was increased. ZP treatment increased the expressions of Runx2 and Osterix in SaOS-2 cells. In summary, ZP treatment inhibited alveolar bone loss as well as maintained the integrity of periodontal structures via regulation of bone remodeling. ZP may be a therapeutic target for treating periodontitis. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Effects of Zanthoxylum piperitum ethanol extract on osteoarthritis inflammation and pain.
Hwang, Kyung-A; Kwon, Jeong Eun; Noh, YooHun; Park, BongKyun; Jeong, Yong Joon; Lee, Sun-Mee; Kim, Se-Young; Kim, InHye; Kang, Se Chan
2018-06-05
Degenerative arthritis, also known as osteoarthritis (OA), is the most common type of arthritis, which is caused by degenerative damage of the cartilage, which primarily protects the joints, leading to inflammation and pain. The objective of this study was to investigate the in vivo and in vitro effects of treatment with ZPE-LR (90% EtOH extract of Zanthoxylum piperitum) on pain severity and inflammation. When using an in vivo OA model MIA (monosodiumidoacetate-induced arthritis) rats, ZPE-LR (100 mg/kg) oral-administratio significantly inhibited MIA-induced change in loaded weight ratio on the left foot, and articular cartilage thickness. To confirm the positive effects on pain relief, acetic acid, heat and formalin-induced pain were remarkably decreased by 50 and 100 mg/kg ZPE-LR oral-administration. Pain related KCNJ6 mRNA expression as well as K + current was increased after ZPE-LR treatment in BV-2 cells. To confirm the positive effects on inflammation, TPA (12-O-tetradecanoylphorbol-13-acetate) induced inflammation measured by mouse ear thickness and biopsy punch weight and TPA-induced iNOS, COX-2 mRNA and protein expression were remarkably suppressed by 50 and 100 mg/kg ZPE-LR oral-administration. In addition, TPA-induced iNOS, COX-2 mRNA level and protein expression were reduced. Acetic acid, heat and formalin-induced pain were remarkably decreased by 50 and 100 mg/kg ZPE-LR oral-administration. We examined in vitro ZPE-LR effects in LPS-induced RAW 264.7 cells. LPS-induced p65 translocation to the nucleus was prohibited by ZPE-LR 100 μg/ml oral administration. Moreover, ROS generation by LPS was significantly inhibited by ZPE-LR 50 and 100 μg/ml treatment. To investigate new ZPE-LR activating mechanisms, the gene fishing method (not a typical term, should probably use PCR based genetic screening) was used. LPS-induced HPRT1 (hypoxanthine phosphoribosyltransferase 1) was decreased by ZPE-LR. However, RPL8 (Ribosomal protein L8) which
Kwon, Hyung Wook; Kim, Soon-Il; Chang, Kyu-Sik; Clark, J Marshall; Ahn, Young-Joon
2011-01-01
The repellency of Zanthoxylum armatum seed oil (ZA-SO), alone or in combination with vanillin (VA), its six major constituents, and another four major previously known Zanthoxylum piperitum fruit oil constituents, as well as aerosol products containing 5 or 10% ZA-SO and 5% VA, was evaluated against female Aedes aegypti in laboratory and field studies. Results were then compared with those of N,N-diethyl-3-methylbenzamide (DEET) as a standard. Hand in cage laboratory tests showed that 0.2, 0.1, and 0.05 mg/cm2 ZA-SO resulted in > 92% protection through 30-min postexposure and was not significantly different than 0.05 mg/cm2 DEET. Skin treated with linalool and limonene (from Z. armatum) provided > 80% repellency to female Ae. aegypti at 10-min exposure, whereas cuminaldehyde, citronellal, geranyl acetate, and cuminyl alcohol (from Zanthoxylum piperitum) provided > 90% protection during this same time period. Only cuminaldehyde and citronellal provided complete protection comparable to DEET at 10-min postexposure. After that time, repellency of all plant constituents to mosquitoes was considerably decreased (< approximately 65%). An increase in repellency and duration of effectiveness was produced by a binary 1:4 mixture of ZA-SO and VA (0.05:0.2 mg/cm2) that was significantly more effective than 0.05 mg/cm2 DEET through 90 min. In field tests, an aerosol formulation containing 5 or 10% ZA-SO plus 5% VA gave 100% repellency at 60-min postexposure. Although these formulations were equal to the level of protection afforded by 10% DEET, repellency to the binary ZA-SO aerosol formulations at 90 min was significantly less effective than DEET. However, mixtures formulated from ZA-SO and VA merit further study as potential repellents for protection of humans and domestic animals from biting and nuisance caused by mosquitoes.
Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells.
Nozaki, Reo; Kono, Toru; Bochimoto, Hiroki; Watanabe, Tsuyoshi; Oketani, Kaori; Sakamaki, Yuichi; Okubo, Naoto; Nakagawa, Koji; Takeda, Hiroshi
2016-10-25
Zanthoxylum fruit, obtained from the Japanese pepper plant (Zanthoxylum piperitum De Candolle), and its extract (Zanthoxylum fruit extract, ZFE) have multiple physiological activities (e.g., antiviral activity). However, the potential anticancer activity of ZFE has not been fully examined. In this study, we investigated the ability of ZFE to induce autophagic cell death (ACD). ZFE caused remarkable autophagy-like cytoplasmic vacuolization, inhibited cell proliferation, and ultimately induced cell death in the human cancer cell lines DLD-1, HepG2, and Caco-2, but not in A549, MCF-7, or WiDr cells. ZFE increased the level of LC3-II protein, a marker of autophagy. Knockdown of ATG5 using siRNA inhibited ZFE-induced cytoplasmic vacuolization and cell death. Moreover, in cancer cells that could be induced to undergo cell death by ZFE, the extract increased the phosphorylation of c-Jun N-terminal kinase (JNK), and the JNK inhibitor SP600125 attenuated both vacuolization and cell death. Based on morphology and expression of marker proteins, ZFE-induced cell death was neither apoptosis nor necrosis. Normal intestinal cells were not affected by ZFE. Taken together, our findings show that ZFE induces JNK-dependent ACD, which appears to be the main mechanism underlying its anticancer activity, suggesting a promising starting point for anticancer drug development.
NASA Astrophysics Data System (ADS)
Muzafri, A.; Julianti, E.; Rusmarilin, H.
2018-02-01
Andaliman (Zanthoxylum acanthopodium DC.) is a well known wild species in North Sumatera and used for seasoning in Batak’s traditional cuisine. This study was aimed to examine the phytochemical constituents of andaliman fruit extracts after simple macerated in water, methanol, ethyl acetate and hexana using qualitative phytochemical analysis, and to determine its potential antimicrobial activity against Staphylococus aureus, Escherichia coli and Salmonella sp by using agar well difussion method and minimum inhibitory concentration (MIC). Phytochemicals such as alkaloids, flavonoid, glycosides, saponins, tannins, triterpene/steroid and glycoside anthroquinones were detected in the methanol extracts, but steroids and glycisode antraquinones were absent in the ethyl acetate extract. The ethyl acetate extracts showed maximum zone of inhibition and minimum inhibitory concentration against all the experimental microorganisms. The minimum zone of inhibition was determined in hexane extracts showing less antimicrobial activity against all the experimental microorganisms. The MIC of the ethyl acetate extracts was 0,5% w/v for all tested bacteria. Apllication of ethyl acetate extracts of andaliman fruits showed effective for catfish (Pangasius Sutchi) fillet stored in refrigerator (5 °C) for 3 days.
Tatsadjieu, L N; Essia Ngang, J J; Ngassoum, M B; Etoa, F-X
2003-07-01
The essential oils of Xylopia aethiopica, Monodora myristica, Zanthoxylum xanthoxyloïdes and Z. leprieurii, four Cameroonian plants used as spices in local food, showed antibacterial and antifungal activity.
Bioactive Lignans from Zanthoxylum alatum Roxb. stem bark with cytotoxic potential.
Mukhija, Minky; Lal Dhar, Kanaya; Nath Kalia, Ajudhia
2014-02-27
Zanthoxylum alatum is used in traditional medicinal systems for number of disorders like cholera, diabetes, cough, diarrhea, fever, headache, microbial infections, toothache, inflammation and cancer. The aim of the present study was to evaluate Zanthoxylum alatum stem bark for its cytotoxic potential and to isolate the bioactive constituents. Cytotoxicity of the different extracts and isolated compounds was studied on lung carcinoma cell line (A549) and pancreatic carcinoma cell line (MIA-PaCa) using MTT assay. Isolation of compounds from most active extract (petroleum ether) was done on silica gel column. Structure elucidation was done by using various spectrophotometric techniques like UV, IR, (1)H NMR, (13)C NMR and mass spectroscopy. The type of cell death caused by most active compound C was explored by fluorescence microscopy using the acridine orange/ethidium bromide method. Petroleum ether extract of plant has shown significant cytotoxic potential. Three lignans sesamin (A), kobusin (B), and 4'O demethyl magnolin (C) has been isolated. All lignans showed cytotoxic activities in different ranges. Compound C was the novel bioactive compound from a plant source and found to be most active. In apoptosis study, treatment caused typical apoptotic morphological changes. It enhances the apoptosis at IC50 dose (21.72 µg/mL) however showing necrotic cell death at higher dose after 24h on MIA-PaCa cell lines. Petroleum ether extract (60-80 °C) of Zanthoxylum alatum has cytotoxic potential. The lignans isolated from the petroleum ether extract were responsible for the cytotoxic potential of the extract. 4'O demethyl magnolin was novel compound from Zanthoxylum alatum. Hence the Zanthoxylum alatum can be further explored for the development of anticancer drug. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Zhang, Da-Shuai; Zhong, Qiong-Xin; Song, Xin-Ming; Liu, Wen-Jie; Wang, Jing; Zhang, Qiong-Yu
2012-08-01
To study the chemical constituents, antimicrobial activity and antitumor activity of the essential oil from Zanthoxylum avicennae. The essential oil from the leaves of Zanthoxylum avicennae was extracted by steam distillation. The components of the essential oil were separated and identified by GC-MS. 72 components were identified and accounted for 98.15% of the all peak area. The essential oil exhibited strong antitumor activity against K-562 human tumor cell lines with IC50 of 1.76 microg/mL. It also exhibited moderate antimicrobial activity against three bacteria. The essential oil of Zanthoxylum avicennae contains various active constituents. This result provides scientific reference for the pharmacological further research of Zanthoxylum avicennae.
Chruma, Jason J; Cullen, Douglas J; Bowman, Lydia; Toy, Patrick H
2018-01-25
Covering up to February 2017The pericarps of several species from the Zanthoxylum genus, a.k.a. the "prickly ash", have long been used for culinary purposes throughout Asia, most notably in the Sichuan (previously Szechuan) cuisine of Southwestern China, due to the unique tingling and numbing orosensations arising from a collection of polyunsaturated fatty acid amide (alkamide) constituents. The past decade has experienced dramatically increased academic and industrial interest in these pungent Zanthoxylum-derived alkamides, with a concomitant explosion in studies aimed at elucidating the specific biochemical mechanisms behind several medically-relevant biological activities exhibited by the natural products. This rapid increase in interest is partially fueled by advances in organic synthesis reported within the past few years that finally have allowed for the production of diastereomerically-pure Zanthoxylum alkamides and related analogs in multigram quantities. Herein is a comprehensive review of the discovery, total synthesis, and biological evaluation of Zanthoxylum-derived polyunsaturated fatty acid amides and synthetic analogues. Critical insights into how chemical synthesis can further benefit future chemical biology efforts in the field are also provided.
Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.
Freitas, F F B P; Fernandes, H B; Piauilino, C A; Pereira, S S; Carvalho, K I M; Chaves, M H; Soares, P M G; Miura, L M C V; Leite, J R S A; Oliveira, R C M; Oliveira, F A
2011-09-01
The stem barks of Zanthoxylum rhoifolium Lam. (Rutaceae), locally known as "mamica de cadela", are popularly used in dyspepsies, stomachic, tonic, antitumoral, antipyretic and are used in treating flatulence and colic. The objective of this study was to evaluate the gastroprotective effect of the ethanolic extract of Zanthoxylum rhoifolium (EEZR) stem barks in acute gastric lesion models, investigating their possible mechanisms. Mice were used for the evaluation of the acute toxicity, and mice and rats to study the gastroprotective activity. The gastroprotective action of EEZR was analyzed in the absolute ethanol, HCl/ethanol and indomethacin-induced gastric lesion models in mice, hypothermic-restraint stress, and ischemia/reperfusion in rats. In the investigation of the gastroprotective mechanisms of EEZR, the participation of the NO-synthase pathway, ATP-sensitive potassium channels (K(ATP)), the levels of the non-protein sulfhydril groups (NP-SH) and the catalase activity using the ethanol-induced gastric mucosa lesion model and the quantification of the gastric mucus and the antisecretory activity through pylorus ligature model in rats were analyzed. The animals did not present any signs of acute toxicity for the EEZR (up to the 4 g/kg dose, po), and it was not possible to calculate the DL(50). EEZR (125-500 mg/kg) exhibited a significant gastroprotective effect in absolute ethanol, HCl/ethanol, hypothermic-restraint stress, and ischemia/reperfusion-induced gastric lesion models. EEZR (250 and 500 mg/kg) exhibited still a gastroprotective activity in the indomethacin-induced ulcer model. Gastroprotection of EEZR was significantly decreased in pre-treated mice with l-NAME or glibenclamide, the respective nitric oxide synthase and K(ATP) channels inhibitors. Our studies revealed that EEZR (500 mg/kg) prevented the decrease of the non-protein sulfhydril groups (NP-SH) and increased the catalase levels in ethanol-treated animals. Furthermore, the extract (500 mg
Antifungal compounds from Zanthoxylum chiloperone var. angustifolium.
Thouvenel, Céline; Gantier, Jean-Charles; Duret, Philippe; Fourneau, Christophe; Hocquemiller, Reynald; Ferreira, Maria-Elena; Rojas de Arias, Antonieta; Fournet, Alain
2003-06-01
An alkaloidal extract of the stem barks of Zanthoxylum chiloperone var. angustifolium exhibited antifungal activity against Candida albicans, Aspergillus fumigatus and Trichophyton mentagrophytes var. interdigitale using a TLC bioautographic method. Bioassay-guided fractionation of this extract resulted in the isolation of two active compounds identi fi ed as canthin-6-one and 5-methoxycanthin-6-one. Canthin-6-one exhibited a broad spectrum of activities against Aspergillus fumigatus, A. niger, A. terreus, Candida albicans, C. tropicalis, C. glabrata, Cryptococcus neoformans, Geotrichum candidum, Saccharomyces cerevisiae, Trichosporon beigelii, Trichosporon cutaneum and Trichophyton mentagrophytes var. interdigitale with MICs values between 5.3 and 46 micro mol/L. 5-methoxy-canthin-6-one was active against only Trichophyton mentagrophytes var. interdigitale with a MIC value of 12.3 micro mol/L. Copyright 2003 John Wiley & Sons, Ltd.
He, Qi; Wang, Wenxia; Zhu, Liang
2018-05-15
Zanthoxylum acanthopodium has insecticidal effect in Chinese traditional medicine. In this study, the essential oil from the dried Zanthoxylum plant was used as a larvicidal compound against the malaria mosquitoes, Anopheles anthropophagus and Anopheles sinensis. Compounds in the Zanthoxylum essential oil were investigated by gas chromatography and mass spectroscopy (GC-MS). The larvicidal bioassays of the whole oil, as well as the main compounds in the oil (estragole and eucalyptol) were performed using WHO method. In total, 63 main compounds (99.32%) were found in the oils, including estragole (15.46%), eucalyptol (10.94%), β-caryophyllene (5.52%), cis-linalool oxide (3.76%), cis-limonene oxide (3.06%). A dose-dependent effect on mortality was recorded with increasing concentrations of essential oil and compounds increasing mortality of the larvae. Larvicidal bioassays revealed that 24 h LC 50 of the whole essential oil was 36.00 mg/L and LC 90 was 101.49 mg/L against An. anthropophagus, while LC 50 was 49.02 mg/L and LC 90 was 125.18 mg/L against An. sinensis. Additionally, 24 h LC 50 of estragole were 38.56 and 41.67 mg/L against An. anthropophagus and An. sinensis, respectively, while the related LC 90 were 95.90 and 107.89 mg/L. LC 50 of eucalyptol were 42.41 and 45.49 mg/L against An. anthropophagus and An. sinensis, while the related LC 90 were 114.45 and 124.95 mg/L. The essential oil of Z. acanthopodium and its several major compounds may have potential for use in the control of malaria mosquitoes.
Sun, Jikang; Wang, Ping; Zhou, Tao; Rong, Jian; Jia, Hao; Liu, Zhiming
2017-08-17
The zanthoxylum seeds are oil-rich and have a very thick, dense and oily shell. In the natural conditions the seeds have a very low germination rate. Prior to treatment with GAs to promote germination, the seeds were usually soaked in sulfuric acid to remove shells easily. A high-throughput sequencing of mRNAs was performed to investigate the effects of the above treatments on the germination of zanthoxylum seeds. Seven libraries were assembled into 100,982 unigenes and 59,509 unigenes were annotated. We focused on the expression profiles of the key genes related to the oil metabolisms and hormone regulations during seed germination. Our data indicated the endogenous ABA of seeds was rich. The effects that the exogenous GAs promoted germination were apparent in the secong day of germination. Especially, for the first time our results indicated the exogenous GAs lowered the aerobic metabolism including the oil metabolisms during imbibition. We inferred that the exogenous GAs had inhibitory effects on the oil metabolisms to avoide oxidative damages to the imbibed seeds, and the seed shell played the role similiar to the exogenous GAs in the initial stage of germination in the natural conditions.
Syncarpamide, a new antiplasmodial (+)-norepinephrine derivative from Zanthoxylum syncarpum.
Ross, Samir A; Sultana, Gazi N N; Burandt, Charles L; ElSohly, Mahmoud A; Marais, Jannie P J; Ferreira, Daneel
2004-01-01
A new (+)-norepinephrine derivative, syncarpamide (1), along with a known coumarin, (+)-S-marmesin (2), and one known alkaloid, decarine (3), have been isolated from the stem of Zanthoxylum syncarpum. The structure of compound 1 was elucidated on the basis of 1D and 2D NMR, MS, IR, optical rotation, and CD analyses. Its absolute stereochemistry was elucidated by synthesis of its enantiomer and subsequent comparison of CD data. Characterizations of compounds 2 and 3 were based on spectral analysis and comparison with reported data. Compounds 1 and 3 showed antiplasmodial activity, with IC(50) values of 2.04 and 1.44 microM against Plasmodium falciparum D(6) clone and 3.06 and 0.88 microM against P. falciparum W(2) clone, respectively. Compound 3 showed cytotoxicity at 56.42 microM, whereas compound 1 was not cytotoxic at 10.42 microM. Compound 1 was tested for hypotensive activity, but no activity was observed. Compound 2 showed no antiplasmodial or antimicrobial activities.
USDA-ARS?s Scientific Manuscript database
Canker disease of prickly ash (Zanthoxylum bungeanum) has caused a decline in the production of this economically important spice in northern China in the past 25 y. To identify the etiological agent, 38 fungal isolates were recovered from symptomatic tissues from trees in five provinces in China. T...
Antibacterial activities of extracts from Ugandan medicinal plants used for oral care.
Ocheng, Francis; Bwanga, Freddie; Joloba, Moses; Borg-Karlson, Ann-Karin; Gustafsson, Anders; Obua, Celestino
2014-08-08
Medicinal plants are widely used for treatment of oral/dental diseases in Uganda. To investigate antibacterial activities of 16 commonly used medicinal plants on microorganisms associated with periodontal diseases (PD) and dental caries (DC). Pulp juice and solvent extracts (hexane, methanol and water) from the plants were tested against Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia associated with PD and Streptococcus mutans, Streptococcus sobrinus, Lactobacillus acidophilus associated with DC. Tests were done using agar well-diffusion (pulp juice) and agar-dilution (Solvent extracts) assays. Pulp juice from Zanthoxylum chalybeum and Euclea latidens showed activity against all the bacteria, Zanthoxylum chalybeum being most active. Hexane extract from aerial part of Helichrysum odoratissimum was most active (MIC: 0.125-0.5 mg/ml). Methanol extract from leaves of Lantana trifolia showed activity against all bacteria (MIC: 0.25-1 mg/ml). Several of the tested plants showed antibacterial activities against bacteria associated with PD and DC, meriting further investigations. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Lee, Jin; Lim, Kye-Taek
2011-08-01
Di(2-ethylhexyl)phthalate (DEHP) is one of the many environmental chemicals that are widely used in polyvinyl chloride products, vinyl flooring, food packaging and infant toys. They cause cell proliferation or dysfunction of human liver. The purpose of this study is to investigate the inhibitory effect of a glycoprotein (24 kDa) isolated from Zanthoxylum piperitum DC (ZPDC) on proliferation of liver cell in the DEHP-induced BNL CL. 2 cells. [³H]-thymidine incorporation, intracellular reactive oxygen species (ROS), intracellular Ca²⁺ mobilization and activity of protein kinase C (PKC) were measured using radioactivity and fluorescence method respectively. The expression of mitogen-activated protein kinases [extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK)], activator protein (AP)-1 (c-Jun and c-Fos), proliferating cell nuclear antigen (PCNA) and cell cycle-related factors (cyclin D1/cyclin-dependent kinase [CDK] 4) were evaluated using Western blotting or electrophoretic mobility shift assay. The results in this study showed that the levels of [³H]-thymidine incorporation, intracellular ROS, intracellular Ca²⁺ mobilization and activity of PKCα were inhibited by ZPDC glycoprotein (100 µg/ml) in the DEHP-induced BNL CL. 2 cells. Also, activities of ERK, JNK and AP-1 were reduced by ZPDC glycoprotein (100 µg/ml). With regard to cell proliferation, activities of PCNA and cyclin D1/CDK4 were significantly suppressed at treatment with ZPDC glycoprotein (100 µg/ml) in the presence of DEHP. Taken together, these findings suggest that ZPDC glycoprotein significantly normalized activities of PCNA and cyclin D1/CDK4, which relate to cell proliferation factors. Thus, ZPDC glycoprotein appears to be one of the compounds derived from natural products that are able to inhibit cell proliferation in the phthalate-induced BNL CL. 2 cells. Copyright © 2011 John Wiley & Sons, Ltd.
Kumar, Vishal; Reddy, S G Eswara; Chauhan, Urvashi; Kumar, Neeraj; Singh, Bikram
2016-01-01
The diamondback moth, Plutella xylostella (L.) (Lepidoptera: Yponomeutidae) is the most serious pest of cruciferous crops grown in the world causing economic yield loss. Several synthetic insecticides have been used against P. xylostella but satisfactory control was not achieved due to development of resistance to insecticides. Therefore, the present study was carried out to screen different fractions of Zanthoxylum armatum for their insecticidal activities against second instar larvae of P. xylostella. Results indicate, all the fractions showed activity to P. xylostella. However, n-hexane fraction of Z. armatum showed maximum larvicidal activity with minimum LC50 value of 2988.6 ppm followed by ethanol (LC50 = 12779.7 ppm) and methanol fraction (LC50 = 12908.8 ppm) whereas chloroform fraction was least toxic (LC50 = 16750.6 ppm). The GC-MS analysis of n-hexane fraction of leaf extract showed maximum larvicidal activity, which may be due to two major compounds i.e. 2-undecanone (19.75%) and 2-tridecanone (11.76%).
Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans Hance
Wang, Chao; Wan, Jinfu; Mei, Zhinan; Yang, Xinzhou
2014-01-01
Background: Zanthoxylum simullans Hance is a popular natural spice belonging to the Rutaceae family and it is one of the common prescribed herbs in traditional Chinese medicine. Materials and Methods: The chemical constituents were mainly isolated and purified by silica gel column chromatography and semi-preparative High Performance Liquid Chromatography. Their structures were identified by comparing the spectral data with those reported in the literature. Cytotoxic activities for the isolated acridone alkaloids were evaluated against two prostate cancer cell lines PC-3M and Lymph Node Carcinoma of Prostate (LNCaP), and their antimalarial activities were tested against two different strains of the parasite Plasmodium falciparum 3D7, and Dd2. Results: The root bark MeOH extract of Z. simullans Hance afforded β-sitosterol, 4-methoxy benzoic acid, daucosterol, and five acridone alkaloids, normelicopidine, normelicopine, melicopine, melicopidine, and melicopicine. All five acridone alkaloids were isolated from this plant for the first time and exhibited certain cytotoxic and antimalarial activities in vitro. Conclusion: Normelicopidine was the most active against PC-3M, LNCaP and Dd2 with IC50 values of 12.5, 21.1, and 18.9 ug/mL respectively. PMID:24696549
NASA Astrophysics Data System (ADS)
Pedersen, F.
2008-09-01
The presented bidirectional DC/DC converter design concept is a further development of an already existing converter used for low battery voltage operation.For low battery voltage operation a high efficient low parts count DC/DC converter was developed, and used in a satellite for the battery charge and battery discharge function.The converter consists in a bidirectional, non regulating DC/DC converter connected to a discharge regulating Buck converter and a charge regulating Buck converter.The Bidirectional non regulating DC/DC converter performs with relatively high efficiency even at relatively high currents, which here means up to 35Amps.This performance was obtained through the use of power MOSFET's with on- resistances of only a few mille Ohms connected to a special transformer allowing paralleling several transistor stages on the low voltage side of the transformer. The design is patent protected. Synchronous rectification leads to high efficiency at the low battery voltages considered, which was in the range 2,7- 4,3 Volt DC.The converter performs with low switching losses as zero voltage zero current switching is implemented in all switching positions of the converter.Now, the drive power needed, to switch a relatively large number of low Ohm , hence high drive capacitance, power MOSFET's using conventional drive techniques would limit the overall conversion efficiency.Therefore a resonant drive consuming considerable less power than a conventional drive circuit was implemented in the converter.To the originally built and patent protected bidirectional non regulating DC/DC converter, is added the functionality of regulation.Hereby the need for additional converter stages in form of a Charge Buck regulator and a Discharge Buck regulator is eliminated.The bidirectional DC/DC converter can be used in connection with batteries, motors, etc, where the bidirectional feature, simple design and high performance may be useful.
Wound-healing Activity of Zanthoxylum bungeanum Maxim Seed Oil on Experimentally Burned Rats
Li, Xiao-Qiang; Kang, Rong; Huo, Jun-Cheng; Xie, Yan-Hua; Wang, Si-Wang; Cao, Wei
2017-01-01
Background: The seed oil of Zanthoxylum bungeanum Maxim (ZBSO) is considered to be rich source of fatty acids, mainly oleic and linoleic acids, and has been used for the treatment of burns in Chinese medicine. Objective: We evaluated the healing efficacy of ZBSO and explored its possible mechanism on scalded rats. Materials and Methods: Sprague-Dawley rat models with deep second-degree burns were set up, and ZBSO (500 and 1000 μl/wound) was topically applied twice daily for 7 days and then once daily until wound healing. The therapeutic effects of ZBSO were evaluated by observing wound closure time, decrustation time, wound-healing ratio, and pathological changes. Collagen type-III, matrix metalloproteinase-2 (MMP-2), MMP-9, phospho-nuclear factor-κB (p-NF-κB) p65, inhibitor of NF-κB subunit α p-IκBα, and inhibitor of NF-κB subunit α (IκBα) expression were determined using Western blotting. Results: The ZBSO-treated group showed a higher wound-healing ratio and shorter decrustation and wound closure times than the untreated group. The topical application of ZBSO increased collagen synthesis as evidenced by an increase in hydroxyproline level and upregulated expression of collagen type-III on days 7, 14, and 21 posttreatment. A reduction in MMP-2 and MMP-9 expressions also confirmed the collagen formation efficacy of ZBSO. Furthermore, there was a significant increase in superoxide dismutase levels and a decrease in malondialdehyde levels in ZBSO-treated wounds. ZBSO also decreased tumor necrosis factor alpha, interleukin-1 (IL-1) β, and IL-6 levels in serum, upregulated IκBα, and downregulated p-NF-κB p65 and p-IκBα expression in vivo, indicating the anti-inflammatory action of ZBSO. Conclusion: ZBSO has significant potential to treat burn wounds by accelerating collagen synthesis and the anti-inflammatory cascade of the healing process. SUMMARY The seed oil of Zanthoxylum bungeanum Maxim (ZBSO) is rich of fatty acidsThe healing efficacy of ZBSO on
Bhatt, Vinod; Sharma, Sushila; Kumar, Neeraj; Sharma, Upendra; Singh, Bikram
2017-01-05
The current study presents isolation and characterization of twelve compounds including catechin (1), isovitexin (2), hesperidin (3), psoralin (4), eudesmin (5), kobusin (6), fargesin (7), sesamin (8), asarinin (9), planispine-A (10), α-sanshool (11) and vitexin (12), from the leaves of Zanthoxylum armatum. Further, two rapid and simple ultra performance liquid chromatography-diode array detection (UPLC-DAD) methods were developed for the simultaneous quantitative determination of isolated compounds from Z. armatum leaves. These analytical methods were validated for linearity, precision, accuracy, limit of detection (LOD) and limit of quantification (LOQ). The LOD and LOQ were in the range of 0.06-0.21μg/mL and 0.19-0.69μg/mL, respectively. The validated method was linear (R 2 ≥0.9906), precise in terms of peak area (intra-day RSDs <3.8% and inter-day RSDs <2.7%), and accurate (109.6-92.5%). This is the first report on the isolation and quantification of 1, 2, 4 and 12 in Z. armatum and 3 in Zanthoxylum genus. The methods: were successfully applied to assess the quality of samples collected from different locations of Himachal Pradesh during summer and winter season. The results demonstrated that flavonoids and furofuran lignans were the major constituents in Z. armatum leaves. The developed methods: were further applied for tandem electrospray ionization-mass spectrometry (UPLC-DAD-ESI-MS/MS) and total eighteen compounds were identified including phenolic acid, flavonoids, furofuran lignans, coumarin and isobutyl amides. Copyright © 2016 Elsevier B.V. All rights reserved.
Prakash, Bhanu; Singh, Priyanka; Mishra, Prashant Kumar; Dubey, N K
2012-02-01
The investigation deals with antifungal, antiaflatoxin and antioxidant efficacy of Zanthoxylum alatum Roxb. essential oil (EO), its two major constituents and their comparison with five commonly used organic acid preservatives. The chemical profile of EO, characterized through GC and GC-MS analysis, revealed linalool (56.10%) and methyl cinnamate (19.73%) as major components. The EO, linalool and methyl cinnamate completely inhibited the growth of a toxigenic strain of A. flavus (LHP-10) as well as aflatoxin B(1) secretion at different concentrations. Methyl cinnamate was found to be more efficacious than EO, linalool and five organic acid preservatives, showing antifungal and antiaflatoxigenic efficacy at a low concentration (0.6 μl/ml) and the nature of its toxicity was fungicidal. However, EO showed strong antioxidant activity with an IC(50) value at 5.6 μl/ml. Moreover, EO was found to have negligible mammalian toxicity as its LD(50) value, determined through oral administration on mice, was calculated to be 6124μl/kg body weight during safety profile assessment. During in vivo investigation on fruit systems, the Zanthoxylum EO, when tested as fumigant, provided 66.27% and 86.33% protection respectively at 1.25 μl/ml and 2.5 μl/ml against fungi infesting Piper nigrum L. fruits demonstrating its practical efficacy as a plant based antimicrobial for post harvest application. Copyright © 2011 Elsevier B.V. All rights reserved.
GaN Microwave DC-DC Converters
NASA Astrophysics Data System (ADS)
Ramos Franco, Ignacio
Increasing the operating frequency of switching converters can have a direct impact in the miniaturization and integration of power converters. The size of energy-storage passive components and the difficulty to integrate them with the rest of the circuitry is a major challenge in the development of a fully integrated power supply on a chip. The work presented in this thesis attempts to address some of the difficulties encountered in the design of high-frequency converters by applying concepts and techniques usually used in the design of high-efficiency power amplifiers and high-efficiency rectifiers at microwave frequencies. The main focus is in the analysis, design, and characterization of dc-dc converters operating at microwave frequencies in the low gigahertz range. The concept of PA-rectifier duality, where a high-efficiency power amplifier operates as a high-efficiency rectifier is investigated through non-linear simulations and experimentally validated. Additionally, the concept of a self-synchronous rectifier, where a transistor rectifier operates synchronously without the need of a RF source or driver is demonstrated. A theoretical analysis of a class-E self-synchronous rectifier is presented and validated through non-linear simulations and experiments. Two GaN class-E2 dc-dc converters operating at a switching frequency of 1 and 1.2 GHz are demonstrated. The converters achieve 80 % and 75 % dc-dc efficiency respectively and are among the highest-frequency and highest-efficiency reported in the literature. The application of the concepts established in the analysis of a self-synchronous rectifier to a power amplifier culminated in the development of an oscillating, self-synchronous class-E 2 dc-dc converter. Finally, a proof-of-concept fully integrated GaN MMIC class-E 2 dc-dc converter switching at 4.6 GHz is demonstrated for the first time to the best of our knowledge. The 3.8 mm x 2.6 mm chip contains distributed inductors and does not require any
Kumar, Vishal; Reddy, S G Eswara; Bhardwaj, Anuja; Dolma, Shudh Kirti; Kumar, Neeraj
2016-01-01
Cinnamoyl amides isolated from Zanthoxylum armatum (Rutaceae) and their synthetic analogues were tested for their insecticidal activity against the second instar larvae of diamondback moth, Plutella xylostella (L.) (Lepidoptera: Yponomeutidae) to determine the promising structures with insecticidal activity. Most of the test compounds showed promising activity against larvae of P. xylostella. However, the activities of different compounds varied depending on the presence of different substituents at various positions of both the aromatic rings A and B. Among the tested compounds, 8, N-(3-bromo-4-methoxyphenethyl)cinnamamide showed best larvicidal activity with an LC50 = 62.13 mg/L followed by 6, N-(3׳-bromophenethyl)cinnamamide (LC50=128.49 mg/L) and 2 N-(4׳-methoxyphenylethyl)cinnamamide (LC50 = 225.65 mg/L).
Kumar, Vishal; Reddy, S. G. Eswara; Bhardwaj, Anuja; Dolma, Shudh Kirti; Kumar, Neeraj
2016-01-01
Cinnamoyl amides isolated from Zanthoxylum armatum (Rutaceae) and their synthetic analogues were tested for their insecticidal activity against the second instar larvae of diamondback moth, Plutella xylostella (L.) (Lepidoptera: Yponomeutidae) to determine the promising structures with insecticidal activity. Most of the test compounds showed promising activity against larvae of P. xylostella. However, the activities of different compounds varied depending on the presence of different substituents at various positions of both the aromatic rings A and B. Among the tested compounds, 8, N-(3-bromo-4-methoxyphenethyl)cinnamamide showed best larvicidal activity with an LC50 = 62.13 mg/L followed by 6, N-(3׳-bromophenethyl)cinnamamide (LC50=128.49 mg/L) and 2 N-(4׳-methoxyphenylethyl)cinnamamide (LC50 = 225.65 mg/L). PMID:27231477
Li, Peiqin; Wu, Zhou; Liu, Tao; Wang, Yanan
2016-09-13
This study investigated the biodiversity, phylogeny, and antifungal activity of endophytic fungi isolated from Zanthoxylum bungeanum. A total of 940 isolates obtained were grouped into 93 morphotypes, 43 species, and 23 genera, which were authenticated by molecular identification based on rDNA internal transcribed spacer (ITS) sequence analysis. A high diversity of endophytic fungi from Z. bungeanum are observed with high species richness S (43), Margalef index D' (6.1351), Shannon-Wiener index H' (3.2743), Simpson diversity index Ds (0.9476), PIE index (0.9486), and evenness Pielou index J (0.8705) but a low dominant index λ (0.0524). Significant tissue specificity of the endophytic fungi was observed in Z. bungeanum, and the highest species richness and diversity indexes were obtained in the stem. Phylogenetic analyses of the 93 endophytic isolates were carried out by the neighbor-joining (NJ) method to demonstrate their evolutionary processes. Antifungal activities of endophytic fungi were assayed and eight endophytic isolates showed strong and long-lasting inhibition against host pathogenic fungi Fusarium sambucinum and Pseudocercospora zanthoxyli. Here, for the first time, we systematically demonstrate the biodiversity, phylogeny, and antifungal activity of endophytic fungi associated with Z. bungeanum and reveal the value of sampling different tissues of a given plant to obtain the greatest endophyte species diversity, which might offer a framework for further investigation and utilization of endophytic fungi as aunique source of interesting and useful bioactive compounds.
Li, Peiqin; Wu, Zhou; Liu, Tao; Wang, Yanan
2016-01-01
This study investigated the biodiversity, phylogeny, and antifungal activity of endophytic fungi isolated from Zanthoxylum bungeanum. A total of 940 isolates obtained were grouped into 93 morphotypes, 43 species, and 23 genera, which were authenticated by molecular identification based on rDNA internal transcribed spacer (ITS) sequence analysis. A high diversity of endophytic fungi from Z. bungeanum are observed with high species richness S (43), Margalef index D′ (6.1351), Shannon–Wiener index H′ (3.2743), Simpson diversity index Ds (0.9476), PIE index (0.9486), and evenness Pielou index J (0.8705) but a low dominant index λ (0.0524). Significant tissue specificity of the endophytic fungi was observed in Z. bungeanum, and the highest species richness and diversity indexes were obtained in the stem. Phylogenetic analyses of the 93 endophytic isolates were carried out by the neighbor-joining (NJ) method to demonstrate their evolutionary processes. Antifungal activities of endophytic fungi were assayed and eight endophytic isolates showed strong and long-lasting inhibition against host pathogenic fungi Fusarium sambucinum and Pseudocercospora zanthoxyli. Here, for the first time, we systematically demonstrate the biodiversity, phylogeny, and antifungal activity of endophytic fungi associated with Z. bungeanum and reveal the value of sampling different tissues of a given plant to obtain the greatest endophyte species diversity, which might offer a framework for further investigation and utilization of endophytic fungi as aunique source of interesting and useful bioactive compounds. PMID:27649145
Das, N G; Dhiman, Sunil; Talukdar, P K; Rabha, Bipul; Goswami, Diganta; Veer, Vijay
2015-01-01
Mosquito repellents play an important role in preventing man-mosquito contact. In the present study, we evaluated the synergistic mosquito-repellent activity of Curcuma longa, Pogostemon heyneanus and Zanthoxylum limonella essential oils. The mosquito repellent efficacies of three essential oils were evaluated separately and in combination under laboratory and field conditions. N,N-Diethylphenylacetamide (DEPA) and dimethylphthalate (DMP) were used for comparison of the protection time of the mixture of essential oils. At an optimum concentration of 20%, the essential oils of C. longa, Z. limonella and P. heyneanus provided complete protection times (CPTs) of 96.2, 91.4 and 123.4 min, respectively, against Aedes albopictus mosquitoes in the laboratory. The 1:1:2 mixture of the essential oils provided 329.4 and 391.0 min of CPT in the laboratory and field trials, respectively. The percent increases in CPTs for the essential oil mixture were 30 for DMP and 55 for N,N-diethylphenylacetamide (DEPA). The synergistic repellent activity of the essential oils used in the present study might be useful for developing safer alternatives to synthetic repellents for personal protection against mosquitoes. Copyright © 2015 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.
DC/DC Converter Stability Testing Study
NASA Technical Reports Server (NTRS)
Wang, Bright L.
2008-01-01
This report presents study results on hybrid DC/DC converter stability testing methods. An input impedance measurement method and a gain/phase margin measurement method were evaluated to be effective to determine front-end oscillation and feedback loop oscillation. In particular, certain channel power levels of converter input noises have been found to have high degree correlation with the gain/phase margins. It becomes a potential new method to evaluate stability levels of all type of DC/DC converters by utilizing the spectral analysis on converter input noises.
Multi Bus DC-DC Converter in Electric Hybrid Vehicles
NASA Astrophysics Data System (ADS)
Krithika, V.; Subramaniam, C.; Sridharan, R.; Geetha, A.
2018-04-01
This paper is cotncerned with the design, simulation and fabrication of the prototype of a Multi bus DC- DC converter operating from 42V DC and delivering 14V DC and 260V DC. As a result, three DC buses are interconnected through a single power electronic circuitry. Such a requirement is energized in the development of a hybrid electric automobile which uses the technology of fuel cell. This is implemented by using a Bidirectional DC-DC converter configuration which is ideally suitable for multiple outputs with mutual electrical isolation. For the sake of reduced size and cost of step-up transformer, selection of a high frequency switching cycle at 10 KHz was done.
Early Oscillation Detection for DC/DC Converter Fault Diagnosis
NASA Technical Reports Server (NTRS)
Wang, Bright L.
2011-01-01
The electrical power system of a spacecraft plays a very critical role for space mission success. Such a modern power system may contain numerous hybrid DC/DC converters both inside the power system electronics (PSE) units and onboard most of the flight electronics modules. One of the faulty conditions for DC/DC converter that poses serious threats to mission safety is the random occurrence of oscillation related to inherent instability characteristics of the DC/DC converters and design deficiency of the power systems. To ensure the highest reliability of the power system, oscillations in any form shall be promptly detected during part level testing, system integration tests, flight health monitoring, and on-board fault diagnosis. The popular gain/phase margin analysis method is capable of predicting stability levels of DC/DC converters, but it is limited only to verification of designs and to part-level testing on some of the models. This method has to inject noise signals into the control loop circuitry as required, thus, interrupts the DC/DC converter's normal operation and increases risks of degrading and damaging the flight unit. A novel technique to detect oscillations at early stage for flight hybrid DC/DC converters was developed.
NASA Technical Reports Server (NTRS)
Mclyman, C. W.
1983-01-01
Compact dc/dc inverter uses single integrated-circuit package containing six inverter gates that generate and amplify 100-kHz square-wave switching signal. Square-wave switching inverts 10-volt local power to isolated voltage at another desired level. Relatively high operating frequency reduces size of filter capacitors required, resulting in small package unit.
dc Arc Fault Effect on Hybrid ac/dc Microgrid
NASA Astrophysics Data System (ADS)
Fatima, Zahra
The advent of distributed energy resources (DER) and reliability and stability problems of the conventional grid system has given rise to the wide spread deployment of microgrids. Microgrids provide many advantages by incorporating renewable energy sources and increasing the reliability of the grid by isolating from the main grid in case of an outage. AC microgrids have been installed all over the world, but dc microgrids have been gaining interest due to the advantages they provide over ac microgrids. However the entire power network backbone is still ac and dc microgrids require expensive converters to connect to the ac power network. As a result hybrid ac/dc microgrids are gaining more attention as it combines the advantages of both ac and dc microgrids such as direct integration of ac and dc systems with minimum number of conversions which increases the efficiency by reducing energy losses. Although dc electric systems offer many advantages such as no synchronization and no reactive power, successful implementation of dc systems requires appropriate protection strategies. One unique protection challenge brought by the dc systems is dc arc faults. A dc arc fault is generated when there is a gap in the conductor due to insulation degradation and current is used to bridge the gap, resulting in an arc with very high temperature. Such a fault if it goes undetected and is not extinguished can cause damage to the entire system and cause fires. The purpose of the research is to study the effect of the dc arc fault at different locations in the hybrid ac/dc microgrid and provide insight on the reliability of the grid components when it is impacted by arc faults at various locations in the grid. The impact of dc arc fault at different locations on the performance of the PV array, wind generation, and constant power loads (CPL) interfaced with dc/dc converters is studied. MATLAB/Simulink is used to model the hybrid ac/dc microgrid and arc fault.
Two new families of high-gain dc-dc power electronic converters for dc-microgrids
NASA Astrophysics Data System (ADS)
Prabhala, Venkata Anand Kishore
Distributing the electric power in dc form is an appealing solution in many applications such as telecommunications, data centers, commercial buildings, and microgrids. A high gain dc-dc power electronic converter can be used to individually link low-voltage elements such as solar panels, fuel cells, and batteries to the dc voltage bus which is usually 400 volts. This way, it is not required to put such elements in a series string to build up their voltages. Consequently, each element can function at it optimal operating point regardless of the other elements in the system. In this dissertation, first a comparative study of dc microgrid architectures and their advantages over their ac counterparts is presented. Voltage level selection of dc distribution systems is discussed from the cost, reliability, efficiency, and safety standpoints. Next, a new family of non-isolated high-voltage-gain dc-dc power electronic converters with unidirectional power flow is introduced. This family of converters benefits from a low voltage stress across its switches. The proposed topologies are versatile as they can be utilized as single-input or double-input power converters. In either case, they draw continuous currents from their sources. Lastly, a bidirectional high-voltage-gain dc-dc power electronic converter is proposed. This converter is comprised of a bidirectional boost converter which feeds a switched-capacitor architecture. The switched-capacitor stage suggested here has several advantages over the existing approaches. For example, it benefits from a higher voltage gain while it uses less number of capacitors. The proposed converters are highly efficient and modular. The operating modes, dc voltage gain, and design procedure for each converter are discussed in details. Hardware prototypes have been developed in the lab. The results obtained from the hardware agree with those of the simulation models.
DC to DC power converters and methods of controlling the same
Steigerwald, Robert Louis; Elasser, Ahmed; Sabate, Juan Antonio; Todorovic, Maja Harfman; Agamy, Mohammed
2012-12-11
A power generation system configured to provide direct current (DC) power to a DC link is described. The system includes a first power generation unit configured to output DC power. The system also includes a first DC to DC converter comprising an input section and an output section. The output section of the first DC to DC converter is coupled in series with the first power generation unit. The first DC to DC converter is configured to process a first portion of the DC power output by the first power generation unit and to provide an unprocessed second portion of the DC power output of the first power generation unit to the output section.
Zhang, Huan-li; Gan, Xiao-qing; Fan, Qing-fei; Yang, Jing-jing; Zhang, Ping; Hu, Hua-bin; Song, Qi-shi
2017-01-01
In this study, 44 compounds in the petroleum ether extract of Maqian (Zanthoxylum myriacanthum var. pubescens) bark, a traditional Dai herbal medicine, were identified by GC-MS. Major components included 3(2H)-benzofuranone, asarinin and (dimethoxymethyl)-3-methoxy-benzene. A total of 18 compounds were isolated from the ethyl acetate extracts of Maqian bark by column chromatography and identified by chemical and spectral analyses. Rhoifoline B, zanthoxyline dimethoxy derivative, N-nortidine, nitidine, decarine are the major alkaloids. Both the petroleum ether and ethyl acetate extracts showed significant inhibition on NO production, which imply anti-inflammatory activity, in lipopolysaccharide-induced RAW 264.7 cells without cell toxicity. Decarine is the major anti-inflammatory constituent with NO IC50 values of 48.43 μM on RAW264.7 cells. The petroleum ether extract, the ethyl acetate extract and decarine showed anti-inflammatory activities through inhibiting TNF-α and IL-1β production in lipopolysaccharide-stimulated THP-1 cells without cell toxicity too. Decarine showed anti-inflammatory activity on human colon cells by reducing IL-6 and IL-8 production in TNF-α+IL-1β-induced Caco-2 cells. These results support the use of Maqian bark as a remedy for enteritis and colitis recorded by Dai medicine in China, and elucidate the major pharmacological compounds in Maqian bark. PMID:28383530
Full wave dc-to-dc converter using energy storage transformers
NASA Technical Reports Server (NTRS)
Moore, E. T.; Wilson, T. G.
1969-01-01
Full wave dc-to-dc converter, for an ion thrustor, uses energy storage transformers to provide a method of dc-to-dc conversion and regulation. The converter has a high degree of physical simplicity, is lightweight and has high efficiency.
Radiation Effects on DC-DC Converters
NASA Technical Reports Server (NTRS)
Zhang, De-Xin; AbdulMazid, M. D.; Attia, John O.; Kankam, Mark D. (Technical Monitor)
2001-01-01
In this work, several DC-DC converters were designed and built. The converters are Buck Buck-Boost, Cuk, Flyback, and full-bridge zero-voltage switched. The total ionizing dose radiation and single event effects on the converters were investigated. The experimental results for the TID effects tests show that the voltages of the Buck Buck-Boost, Cuk, and Flyback converters increase as total dose increased when using power MOSFET IRF250 as a switching transistor. The change in output voltage with total dose is highest for the Buck converter and the lowest for Flyback converter. The trend of increase in output voltages with total dose in the present work agrees with those of the literature. The trends of the experimental results also agree with those obtained from PSPICE simulation. For the full-bridge zero-voltage switch converter, it was observed that the dc-dc converter with IRF250 power MOSFET did not show a significant change of output voltage with total dose. In addition, for the dc-dc converter with FSF254R4 radiation-hardened power MOSFET, the output voltage did not change significantly with total dose. The experimental results were confirmed by PSPICE simulation that showed that FB-ZVS converter with IRF250 power MOSFET's was not affected with the increase in total ionizing dose. Single Event Effects (SEE) radiation tests were performed on FB-ZVS converters. It was observed that the FB-ZVS converter with the IRF250 power MOSFET, when the device was irradiated with Krypton ion with ion-energy of 150 MeV and LET of 41.3 MeV-square cm/mg, the output voltage increased with the increase in fluence. However, for Krypton with ion-energy of 600 MeV and LET of 33.65 MeV-square cm/mg, and two out of four transistors of the converter were permanently damaged. The dc-dc converter with FSF254R4 radiation hardened power MOSFET's did not show significant change at the output voltage with fluence while being irradiated by Krypton with ion energy of 1.20 GeV and LET of 25
Liu, Shu-Ming; Wang, Shi-Jun; Song, Si-Yao; Zou, Yong; Wang, Jun-Ru; Sun, Bing-Yin
Great variations have been found in composition and content of the essential oil of Zanthoxylum bungeanum Maxim. (Rutaceae), resulting from various factors such as harvest time, drying and extraction methods (Huang et al., 2006; Shao et al., 2013), solvent and herbal parts used (Zhang, 1996; Cao and Zhang, 2010; Wang et al., 2011). However, in terms of artificial introduction and cultivation, there is little research on the chemical composition of essential oil extracted from Z. bungeanum Maxim. cultivars, which have been introduced from different origins. In this study, the composition and content of essential oil from six cultivars (I-VI) have been investigated. They were introduced and cultivated for 11 years in the same cultivation conditions. Cultivars were as followings: Qin'an (I) cultivar originally introduced from Qin'an City in Gansu Province; Dahongpao A (II) from She County in Hebei Province; Dahongpao B (III) from Fuping County; Dahongpao C (IV) from Tongchuan City; Meifengjiao (V) from Feng County; and, Shizitou (VI) from Hancheng City, in Shaanxi Province, China. This research is expected to provide a theoretical basis for further introduction, cultivation, and commercial development of Z. bungeanum Maxim.
Early Oscillation Detection Technique for Hybrid DC/DC Converters
NASA Technical Reports Server (NTRS)
Wang, Bright L.
2011-01-01
Oscillation or instability is a situation that must be avoided for reliable hybrid DC/DC converters. A real-time electronics measurement technique was developed to detect catastrophic oscillations at early stages for hybrid DC/DC converters. It is capable of identifying low-level oscillation and determining the degree of the oscillation at a unique frequency for every individual model of the converters without disturbing their normal operations. This technique is specially developed for space-used hybrid DC/DC converters, but it is also suitable for most of commercial and military switching-mode power supplies. This is a weak-electronic-signal detection technique to detect hybrid DC/DC converter oscillation presented as a specific noise signal at power input pins. It is based on principles of feedback control loop oscillation and RF signal modulations, and is realized by using signal power spectral analysis. On the power spectrum, a channel power amplitude at characteristic frequency (CPcf) and a channel power amplitude at switching frequency (CPsw) are chosen as oscillation level indicators. If the converter is stable, the CPcf is a very small pulse and the CPsw is a larger, clear, single pulse. At early stage of oscillation, the CPcf increases to a certain level and the CPsw shows a small pair of sideband pulses around it. If the converter oscillates, the CPcf reaches to a higher level and the CPsw shows more high-level sideband pulses. A comprehensive stability index (CSI) is adopted as a quantitative measure to accurately assign a degree of stability to a specific DC/DC converter. The CSI is a ratio of normal and abnormal power spectral density, and can be calculated using specified and measured CPcf and CPsw data. The novel and unique feature of this technique is the use of power channel amplitudes at characteristic frequency and switching frequency to evaluate stability and identify oscillations at an early stage without interfering with a DC/DC converter s
Triple voltage dc-to-dc converter and method
Su, Gui-Jia
2008-08-05
A circuit and method of providing three dc voltage buses and transforming power between a low voltage dc converter and a high voltage dc converter, by coupling a primary dc power circuit and a secondary dc power circuit through an isolation transformer; providing the gating signals to power semiconductor switches in the primary and secondary circuits to control power flow between the primary and secondary circuits and by controlling a phase shift between the primary voltage and the secondary voltage. The primary dc power circuit and the secondary dc power circuit each further comprising at least two tank capacitances arranged in series as a tank leg, at least two resonant switching devices arranged in series with each other and arranged in parallel with the tank leg, and at least one voltage source arranged in parallel with the tank leg and the resonant switching devices, said resonant switching devices including power semiconductor switches that are operated by gating signals. Additional embodiments having a center-tapped battery on the low voltage side and a plurality of modules on both the low voltage side and the high voltage side are also disclosed for the purpose of reducing ripple current and for reducing the size of the components.
Agamy, Mohammed; Elasser, Ahmed; Sabate, Juan Antonio; Galbraith, Anthony William; Harfman Todorovic, Maja
2014-09-09
A distributed photovoltaic (PV) power plant includes a plurality of distributed dc-dc converters. The dc-dc converters are configured to switch in coordination with one another such that at least one dc-dc converter transfers power to a common dc-bus based upon the total system power available from one or more corresponding strings of PV modules. Due to the coordinated switching of the dc-dc converters, each dc-dc converter transferring power to the common dc-bus continues to operate within its optimal efficiency range as well as to optimize the maximum power point tracking in order to increase the energy yield of the PV power plant.
Analysis of self-oscillating dc-to-dc converters
NASA Technical Reports Server (NTRS)
Burger, P.
1974-01-01
The basic operational characteristics of dc-to-dc converters are analyzed along with the basic physical characteristics of power converters. A simple class of dc-to-dc power converters are chosen which could satisfy any set of operating requirements, and three different controlling methods in this class are described in detail. Necessary conditions for the stability of these converters are measured through analog computer simulation whose curves are related to other operational characteristics, such as ripple and regulation. Further research is suggested for the solution of absolute stability and efficient physical design of this class of power converters.
Lifting properties of the alkamide fraction from the fruit husks of Zanthoxylum bungeanum.
Artaria, C; Maramaldi, G; Bonfigli, A; Rigano, L; Appendino, G
2011-08-01
The fruits of various Zanthoxylum species are used as a spice in the Chinese and Japanese cuisine because of their delicate flavour and tingling properties. The lipophilic hydroxyalkamides hydroxy α- and β-sanshools (1a,b) have been identified as the tingling principles of these plants, and previous studies have validated a sanshool-rich lipophilic extract from the fruit husks of Z. bungeanum Maxim. (Zanthalene ® ) as an anti-itching cosmetic ingredient. Because tingling is a sort of 'paralytic pungency', and Zanthalene ® potently inhibits synaptic transmission, we have investigated its capacity to relax subcutaneous muscles and act as a topical lifting agent for wrinkles. An anti-wrinkles extract rich in spilanthol (2), a lipophilic alkamide having sensory properties similar to those of Zanthalene ® , was used as a reference. Short-term (lifting effect) and long-term (anti-wrinkle) improvements of skin roughness parameters were evaluated by both objectives' and subjectives' measurements. An immediate 'lifting' effect was observed with the sanshool-rich lipophilic extract, at dosages at which the reference alkamide extract was inactive in the objective assays. Limited desensitization after repeated application and good overall tolerability were observed, although a modest long-term anti-wrinkle effect was shown by both products. Taken together, these observations validate the use of sanshool-rich lipophilic extracts as an efficacious, immediate-action lifting agent, and exemplify the relevance of sensory observations to foster the development of innovative cosmetic ingredients. © 2011 The Authors. ICS © 2011 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-07
... reviewed Boeing Service Bulletins DC9-28-212 (for Model DC- 9-30, DC-9-40, and DC-9-50 series airplanes... on airplanes changed in accordance with Boeing Service Bulletin DC9-28-212 or MD90-28-010, both dated... accomplishing the modification). Boeing Service Bulletins DC9-28-212 and MD90-28-010, both Revision 1, both...
Early Oscillation Detection for Hybrid DC/DC Converter Fault Diagnosis
NASA Technical Reports Server (NTRS)
Wang, Bright L.
2011-01-01
This paper describes a novel fault detection technique for hybrid DC/DC converter oscillation diagnosis. The technique is based on principles of feedback control loop oscillation and RF signal modulations, and Is realized by using signal spectral analysis. Real-circuit simulation and analytical study reveal critical factors of the oscillation and indicate significant correlations between the spectral analysis method and the gain/phase margin method. A stability diagnosis index (SDI) is developed as a quantitative measure to accurately assign a degree of stability to the DC/DC converter. This technique Is capable of detecting oscillation at an early stage without interfering with DC/DC converter's normal operation and without limitations of probing to the converter.
ERIC Educational Resources Information Center
Martinez-Rodrigo, Fernando; Herrero-De Lucas, Luis Carlos; de Pablo, Santiago; Rey-Boue, Alexis B.
2017-01-01
This paper examines the question of how to use project-based learning to increase student performance and satisfaction in a power electronics course addressing the topics of dc/dc and dc/ac converters, the assembly of a dc/dc converter, and the use of a commercial speed drive. A detailed presentation of the methodology is shown, and the results…
Digital Control Technologies for Modular DC-DC Converters
NASA Technical Reports Server (NTRS)
Button, Robert M.; Kascak, Peter E.; Lebron-Velilla, Ramon
2002-01-01
Recent trends in aerospace Power Management and Distribution (PMAD) systems focus on using commercial off-the-shelf (COTS) components as standard building blocks. This move to more modular designs has been driven by a desire to reduce costs and development times, but is also due to the impressive power density and efficiency numbers achieved by today's commercial DC-DC converters. However, the PMAD designer quickly learns of the hidden "costs" of using COTS converters. The most significant cost is the required addition of external input filters to meet strict electromagnetic interference (MIAMI) requirements for space systems. In fact, the high power density numbers achieved by the commercial manufacturers are greatly due to the lack of necessary input filters included in the COTS module. The NASA Glenn Research Center is currently pursuing a digital control technology that addresses this problem with modular DC-DC converters. This paper presents the digital control technologies that have been developed to greatly reduce the input filter requirements for paralleled, modular DC-DC converters. Initial test result show that the input filter's inductor size was reduced by 75 percent, and the capacitor size was reduced by 94 percent while maintaining the same power quality specifications.
High power density dc/dc converter: Selection of converter topology
NASA Technical Reports Server (NTRS)
Divan, Deepakraj M.
1990-01-01
The work involved in the identification and selection of a suitable converter topology is described. Three new dc/dc converter topologies are proposed: Phase-Shifted Single Active Bridge DC/DC Converter; Single Phase Dual Active Bridges DC/DC Converter; and Three Phase Dual Active Bridges DC/DC Converter (Topology C). The salient features of these topologies are: (1) All are minimal in structure, i.e., each consists of an input and output bridge, input and output filter and a transformer, all components essential for a high power dc/dc conversion process; (2) All devices of both the bridges can operate under near zero-voltage conditions, making possible a reduction of device switching losses and hence, an increase in switching frequency; (3) All circuits operate at a constant frequency, thus simplifying the task of the magnetic and filter elements; (4) Since, the leakage inductance of the transformer is used as the main current transfer element, problems associated with the diode reverse recovery are eliminated. Also, this mode of operation allows easy paralleling of multiple modules for extending the power capacity of the system; (5) All circuits are least sensitive to parasitic impedances, infact the parasitics are efficently utilized; and (6) The soft switching transitions, result in low electromagnetic interference. A detailed analysis of each topology was carried out. Based on the analysis, the various device and component ratings for each topology operating at an optimum point, and under the given specifications, are tabulated and discussed.
Carotenuto, Gennaro; Carrieri, Raffaele; Tarantino, Paola; Alfieri, Mariaevelina; Leone, Antonella; De Tommasi, Nunziatina; Lahoz, Ernesto
2015-01-01
Plant-derived compounds are emerging as an alternative choice to synthetic fungicides. Chloroform-methanol extract, obtained from the bark of Zanthoxylum rhoifolium, a member of Rutaceae, showed a fungistatic effect on Botrytis cinerea, Sclerotinia sclerotiorum, Alternaria alternata, Colletotrichum gloeosporioides and Clonostachys rosea, when added to the growth medium at different concentrations. A fraction obtained by gel separation and containing the alkaloid O-Methylcapaurine showed significant fungistatic effect against B. cinerea and S. sclerotiorum, two of the most destructive phytopathogenic fungi. The underlying mechanism of such an inhibition was further investigated in B. cinerea, a fungus highly prone to develop fungicide resistance, by analysing the expression levels of a set of genes (BcatrB, P450, CYP51 and TOR). O-Methylcapaurine inhibited the expression of all the analysed genes. In particular, the expression of BcatrB gene, encoding a membrane drug transporter involved in the resistance to a wide range of xenobiotic compounds, was strongly inhibited (91%).
Efficient Design in a DC to DC Converter Unit
NASA Technical Reports Server (NTRS)
Bruemmer, Joel E.; Williams, Fitch R.; Schmitz, Gregory V.
2002-01-01
Space Flight hardware requires high power conversion efficiencies due to limited power availability and weight penalties of cooling systems. The International Space Station (ISS) Electric Power System (EPS) DC-DC Converter Unit (DDCU) power converter is no exception. This paper explores the design methods and tradeoffs that were utilized to accomplish high efficiency in the DDCU. An isolating DC to DC converter was selected for the ISS power system because of requirements for separate primary and secondary grounds and for a well-regulated secondary output voltage derived from a widely varying input voltage. A flyback-current-fed push-pull topology or improved Weinberg circuit was chosen for this converter because of its potential for high efficiency and reliability. To enhance efficiency, a non-dissipative snubber circuit for the very-low-Rds-on Field Effect Transistors (FETs) was utilized, redistributing the energy that could be wasted during the switching cycle of the power FETs. A unique, low-impedance connection system was utilized to improve contact resistance over a bolted connection. For improved consistency in performance and to lower internal wiring inductance and losses a planar bus system is employed. All of these choices contributed to the design of a 6.25 KW regulated dc to dc converter that is 95 percent efficient. The methodology used in the design of this DC to DC Converter Unit may be directly applicable to other systems that require a conservative approach to efficient power conversion and distribution.
Multielement analysis of Zanthoxylum bungeanum Maxim. essential oil using ICP-MS/MS.
Fu, Liang; Xie, Hualin; Shi, Shuyun
2018-06-01
The concentrations of trace elements (Cr, Ni, As, Cd, Hg, and Pb) in Zanthoxylum bungeanum Maxim. essential oil (ZBMEO) were determined by inductively coupled plasma tandem mass spectrometry. The ZBMEO sample was directly analyzed after simple dilution with n-hexane. Aiming for a relatively high vapor pressure of n-hexane and its resultant loading on plasma, we used a narrow injector torch and optimized plasma radio frequency power and carrier gas flow to ensure stable operation of the plasma. An optional gas flow of 20% O 2 in Ar was added to the carrier gas to prevent the incomplete combustion of highly concentrated organic carbon in plasma and the deposition of carbon on the sampling and skimmer cone orifices. In tandem mass spectrometry mode, O 2 was added to the collision/reaction cell to eliminate the interferences. The limits of detection for Cr, Ni, As, Cd, Hg, and Pb were 2.26, 1.64, 2.02, 1.35, 1.76, and 0.97 ng L -1 , respectively. After determination of 23 ZBMEO samples from different regions in China, we found that the average concentration ranges of trace elements in the 23 ZBMEO samples were 0.72-6.02 ng g -1 , 0.09-2.87 ng g -1 , 0.21-5.84 ng g -1 , 0.16-2.15 ng g -1 , 0.13-0.92 ng g -1 , and 0.17-0.73 ng g -1 for Cr, Ni, As, Cd, Hg, and Pb, respectively. The trace elements in ZBMEO differed significantly when different extraction technologies were used. The study revealed that the contents of the toxic elements As, Cd, Hg, and Pb were extremely low, and hence they are unlikely to pose a health risk following ZBMEO ingestion. Graphical abstract The working mechanism of sample analysis by ICP-MS/MS.
Tiku, A. K.; Koul, Apurva; Gupta, Sahil; Singh, Gurjinder; Razdan, V. K.
2013-01-01
The essential oil obtained from the fresh leaves of Zanthoxylum alatum was analysed by gas chromatography/mass spectrometry (GC/MS). Fourteen components were identified, and linalool (30.58%), 2-decanone (20.85%), β-fenchol (9.43%), 2-tridecanone (8.86%), β-phellandrene (5.99%), Sabinene (4.82%), and α-pinene (4.11%) were the main components. The EO and methanolic extract of Z. alatum exhibited potent antifungal activity against Alternaria alternata, Alternaria brassicae, and Curvularia lunata. The EO also showed significant antibacterial activity against Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus, and Escherichia coli. Further, antimicrobial constituents of the EO were isolated by bioautography and preparative thin layer chromatography (PTLC) and identified as β-fenchol and linalool using GC/MS analysis. In addition to this, the free radical scavenging activity and antioxidant potential of EO and methanolic extract/fractions of Z. alatum were also investigated using in vitro assays including scavenging ability against DPPH•, reducing power and chelating ability on Fe2+ ions. Our results demonstrate that Z. alatum could be used as a resource of antioxidant and antimicrobial compounds which may find applications in food and pesticide industries. PMID:23781160
Decentralized Interleaving of Paralleled Dc-Dc Buck Converters
DOE Office of Scientific and Technical Information (OSTI.GOV)
Johnson, Brian B; Rodriguez, Miguel; Sinha, Mohit
We present a decentralized control strategy that yields switch interleaving among parallel-connected dc-dc buck converters. The proposed method is based on the digital implementation of the dynamics of a nonlinear oscillator circuit as the controller. Each controller is fully decentralized, i.e., it only requires the locally measured output current to synthesize the pulse width modulation (PWM) carrier waveform and no communication between different controllers is needed. By virtue of the intrinsic electrical coupling between converters, the nonlinear oscillator-based controllers converge to an interleaved state with uniform phase-spacing across PWM carriers. To the knowledge of the authors, this work presents themore » first fully decentralized strategy for switch interleaving in paralleled dc-dc buck converters.« less
Advanced DC/DC Converters Towards Higher Volumetric Efficiencies For Space Applications
NASA Technical Reports Server (NTRS)
Shaw, Harry; Shue, Jack; Liu, David; Wang, Bright; Plante, Jeanette
2005-01-01
A new emphasis on planetary exploration by NASA drives the need for small, high power DC/DC converters which are functionally modular. NASA GSFC and other government space organizations are supporting technology development in the DC/DC converter area to both meet new needs and to promote more sources of supply. New technologies which enable miniaturization such as embedded passive technologies and thermal management using high thermal conductivity materials are features of the new designs. Construction of some simple DC/DC converter core circuits using embedded components was found to be successful for increasing volumetric efficiency to 37 W/inch. The embedded passives were also able to perform satisfactorily in this application in cryogenic temperatures.
Zhang, Mengmeng; Wang, Jiaolong; Zhu, Lei; Li, Tao; Jiang, Weidong; Zhou, Juan; Peng, Wei; Wu, Chunjie
2017-01-01
Zanthoxylum bungeanum Maxim. (Rutaceae) is a popular food additive and traditional Chinese herbal medicine commonly named HuaJiao in China. This plant is widely distributed in Asian countries. The aim of this paper is to provide a systematic review on the traditional usages, botany, phytochemistry, pharmacology, pharmacokinetics, and toxicology of this plant. Furthermore, the possible development and perspectives for future research on this plant are also discussed. To date, over 140 compounds have been isolated and identified from Z. bungeanum, including alkaloids, terpenoids, flavonoids, and free fatty acids. The extracts and compounds have been shown to possess wide-ranging biological activity, such as anti-inflammatory and analgesic effects, antioxidant and anti-tumor effects, antibacterial and antifungal effects, as well as regulatory effects on the gastrointestinal system and nervous system, and other effects. As a traditional herbal medicine, Z. bungeanum has been widely used to treat many diseases, especially digestive disorders, toothache, stomach ache, and diarrhea. Many traditional usages of this plant have been validated by present investigations. However, further research elucidating the structure-function relationship among chemical compounds, understanding the mechanism of unique sensation, as well as exploring new clinical effects and establishing criteria for quality control for Z. bungeanum should be further studied. PMID:29057808
Zhang, Mengmeng; Wang, Jiaolong; Zhu, Lei; Li, Tao; Jiang, Weidong; Zhou, Juan; Peng, Wei; Wu, Chunjie
2017-10-18
Zanthoxylum bungeanum Maxim. (Rutaceae) is a popular food additive and traditional Chinese herbal medicine commonly named HuaJiao in China. This plant is widely distributed in Asian countries. The aim of this paper is to provide a systematic review on the traditional usages, botany, phytochemistry, pharmacology, pharmacokinetics, and toxicology of this plant. Furthermore, the possible development and perspectives for future research on this plant are also discussed. To date, over 140 compounds have been isolated and identified from Z. bungeanum , including alkaloids, terpenoids, flavonoids, and free fatty acids. The extracts and compounds have been shown to possess wide-ranging biological activity, such as anti-inflammatory and analgesic effects, antioxidant and anti-tumor effects, antibacterial and antifungal effects, as well as regulatory effects on the gastrointestinal system and nervous system, and other effects. As a traditional herbal medicine, Z. bungeanum has been widely used to treat many diseases, especially digestive disorders, toothache, stomach ache, and diarrhea. Many traditional usages of this plant have been validated by present investigations. However, further research elucidating the structure-function relationship among chemical compounds, understanding the mechanism of unique sensation, as well as exploring new clinical effects and establishing criteria for quality control for Z. bungeanum should be further studied.
Melo, Bernardo; Leitão, Joseana M S R; Oliveira, Luciano G C; Santos, Sérgio E M; Carneiro, Sabrina M P; Rodrigues, Klinger A F; Chaves, Mariana H; Arcanjo, Daniel D R; Carvalho, Fernando A A
2016-01-01
Zanthoxylum rhoifolium Lam. (Rutaceae) has been traditionally used in the treatment of microbial infections and parasitic diseases. In the present study, the antileishmanial effect induced by the ethanol extract of stem barks from Z. rhoifolium (ZR-EEtOH) and its n-hexane fraction (ZR-FHEX) on infection and infectivity of murine macrophages by promastigote forms of Leishmania amazonensis were investigated. In different set of experiments, macrophages or promastigotes were pretreated with ZR-EEtOH or ZR-FHEX at non-lethal concentrations for 24 hours, and then macrophages were submitted to infection by promastigotes. Moreover, their effects on activation of macrophages, as well as on the DNA content, size and number of promastigotes by flow cytometry were also evaluated. The infection rate and the number of internalized amastigote forms were markedly decreased after pretreatment of macrophages or promastigotes when compared with non-treated cells. The increase in phagocytic capability and nitrite content was also observed. Furthermore, the decrease of DNA content, size and number of promastigotes was also observed. In conclusion, ZR-EEtOH and ZR-FHEX promoted a markedly significant antileishmanial effect and reduction of infection of macrophages, probably underlying defense mechanisms activation in macrophages. These findings reinforce the potential application of Z. rhoifolium in the treatment of leishmaniasis.
Wei, Shigang; Zhang, Huihui; Wang, Yeqiang; Wang, Lu; Li, Xueyuan; Wang, Yinghua; Zhang, Hanqi; Xu, Xu; Shi, Yuhua
2011-07-22
The ultrasonic nebulization extraction-heating gas flow transfer coupled with headspace single drop microextraction (UNE-HGFT-HS-SDME) was developed for the extraction of essential oil from Zanthoxylum bungeanum Maxim. The gas chromatography-mass spectrometry was applied to the determination of the constituents in the essential oil. The contents of the constituents from essential oil obtained by the proposed method were found to be more similar to those obtained by hydro-distillation (HD) than those obtained by ultrasonic nebulization extraction coupled with headspace single drop microextraction (UNE-HS-SDME). The heating gas flow was firstly used in the analysis of the essential oil to transfer the analytes from the headspace to the solvent microdrop. The relative standard deviations for determining the five major constituents were in the range from 1.5 to 6.7%. The proposed method is a fast, sensitive, low cost and small sample consumption method for the determination of the volatile and semivolatile constituents in the plant materials. Copyright © 2011 Elsevier B.V. All rights reserved.
Isolated step-down DC -DC converter for electric vehicles
NASA Astrophysics Data System (ADS)
Kukovinets, O. V.; Sidorov, K. M.; Yutt, V. E.
2018-02-01
Modern motor-vehicle industrial sector is moving rapidly now towards the electricity-driving cars production, improving their range and efficiency of components, and in particular the step-down DC/DC converter to supply the onboard circuit 12/24V of electric vehicle from the high-voltage battery. The purpose of this article - to identify the best circuitry topology to design an advanced step-down DC/DC converters with the smallest mass, volume, highest efficiency and power. And this will have a positive effect on driving distance of electric vehicle (EV). On the basis of computational research of existing and implemented circuit topologies of step-down DC/DC converters (serial resonant converter, full bridge with phase-shifting converter, LLC resonant converter) a comprehensive analysis was carried out on the following characteristics: specific volume, specific weight, power, efficiency. The data obtained was the basis for the best technical option - LLC resonant converter. The results can serve as a guide material in the process of components design of the traction equipment for electric vehicles, providing for the best technical solutions in the design and manufacturing of converting equipment, self-contained power supply systems and advanced driver assistance systems.
Piezometer completion report for borehole cluster sites DC-19, DC-20, and DC-22
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jackson, R.L.; Diediker, L.D.; Ledgerwood, R.K.
1984-07-01
This report describes the design and installation of multi-level piezometers at borehole cluster sites DC-19, DC-20 and DC-22. The network of borehole cluster sites will provide facilities for multi-level water-level monitoring across the RRL for piezometer baseline monitoring and for large-scale hydraulic stress testing. These groundwater-monitoring facilities were installed between August 1983 and March 1984. Three series of piezometer nests (A-, C- and D-series) were installed in nine hydrogeologic units (monitoring horizons) within the Columbia River Basalt Group at each borehole cluster site. In addition to the piezometer facilities, a B-series pumping well was installed at borehole cluster sites DC-20more » and DC-22. The A-series piezometer nest monitors the basal Ringold sediments and the Rattlesnake Ridge interbed. The C-series piezometer nests monitors the six deepest horizons, which are in increasing depth, the Priest Rapids interflow, Sentinel Gap flow top, Ginkgo flow top, Rocky Coulee flow top, Cohassett flow top and Umtanum flow top. The D-series piezometer monitors the Mabton interbed. The B-series pumping well was completed in the Priest Rapids interflow. 21 refs., 6 figs., 6 tabs.« less
Multiple high voltage output DC-to-DC power converter
NASA Technical Reports Server (NTRS)
Cronin, Donald L. (Inventor); Farber, Bertrand F. (Inventor); Gehm, Hartmut K. (Inventor); Goldin, Daniel S. (Inventor)
1977-01-01
Disclosed is a multiple output DC-to-DC converter. The DC input power is filtered and passed through a chopper preregulator. The chopper output is then passed through a current source inverter controlled by a squarewave generator. The resultant AC is passed through the primary winding of a transformer, with high voltages induced in a plurality of secondary windings. The high voltage secondary outputs are each solid-state rectified for passage to individual output loads. Multiple feedback loops control the operation of the chopper preregulator, one being responsive to the current through the primary winding and another responsive to the DC voltage level at a selected output.
Study on preparation method of Zanthoxylum bungeanum seeds kernel oil with zero trans-fatty acids.
Liu, Tong; Yao, Shi-Yong; Yin, Zhong-Yi; Zheng, Xu-Xu; Shen, Yu
2016-04-01
The seed of Zanthoxylum bungeanum (Z. bungeanum) is a by-product of pepper production and rich in unsaturated fatty acid, cellulose, and protein. The seed oil obtained from traditional producing process by squeezing or extracting would be bad quality and could not be used as edible oil. In this paper, a new preparation method of Z. bungeanum seed kernel oil (ZSKO) was developed by comparing the advantages and disadvantages of alkali saponification-cold squeezing, alkali saponification-solvent extraction, and alkali saponification-supercritical fluid extraction with carbon dioxide (SFE-CO2). The results showed that the alkali saponification-cold squeezing could be the optimal preparation method of ZSKO, which contained the following steps: Z. bungeanum seed was pretreated by alkali saponification under the conditions of adding 10 %NaOH (w/w), solution temperature was 80 °C, and saponification reaction time was 45 min, and pretreated seed was separated by filtering, water washing, and overnight drying at 50 °C, then repeated squeezing was taken until no oil generated at 60 °C with 15 % moisture content, and ZSKO was attained finally using centrifuge. The produced ZSKO contained more than 90 % unsaturated fatty acids and no trans-fatty acids and be testified as a good edible oil with low-value level of acid and peroxide. It was demonstrated that the alkali saponification-cold squeezing process could be scaled up and applied to industrialized production of ZSKO.
Campbell, Jeremy B; Newson, Steve
2013-02-26
Embodiments of DC source assemblies of power inverter systems of the type suitable for deployment in a vehicle having an electrically grounded chassis are provided. An embodiment of a DC source assembly comprises a housing, a DC source disposed within the housing, a first terminal, and a second terminal. The DC source also comprises a first capacitor having a first electrode electrically coupled to the housing, and a second electrode electrically coupled to the first terminal. The DC source assembly further comprises a second capacitor having a first electrode electrically coupled to the housing, and a second electrode electrically coupled to the second terminal.
NASA Technical Reports Server (NTRS)
Sander, W. A., III
1973-01-01
Dc to dc static power conditioning systems on unmanned spacecraft have as their inputs highly fluctuating dc voltages which they condition to regulated dc voltages. These input voltages may be less than or greater than the desired regulated voltages. The design of two circuits which address specific problems in the design of these power conditioning systems and a nonlinear analysis of one of the circuits are discussed. The first circuit design is for a nondissipative active ripple filter which uses an operational amplifier to amplify and cancel the sensed ripple voltage. A dc to dc converter operating at a switching frequency of 1 MHz is the second circuit discussed. A nonlinear analysis of the type of dc to dc converter utilized in designing the 1 MHz converter is included.
Decentralized Interleaving of Paralleled Dc-Dc Buck Converters: Preprint
DOE Office of Scientific and Technical Information (OSTI.GOV)
Johnson, Brian B; Rodriguez, Miguel; Sinha, Mohit
We present a decentralized control strategy that yields switch interleaving among parallel connected dc-dc buck converters without communication. The proposed method is based on the digital implementation of the dynamics of a nonlinear oscillator circuit as the controller. Each controller is fully decentralized, i.e., it only requires the locally measured output current to synthesize the pulse width modulation (PWM) carrier waveform. By virtue of the intrinsic electrical coupling between converters, the nonlinear oscillator-based controllers converge to an interleaved state with uniform phase-spacing across PWM carriers. To the knowledge of the authors, this work represents the first fully decentralized strategy formore » switch interleaving of paralleled dc-dc buck converters.« less
Materials Testing on the DC-X and DC-XA
NASA Technical Reports Server (NTRS)
Smith, Dane; Carroll, Carol; Marschall, Jochen; Pallix, Joan
1997-01-01
Flight testing of thermal protection materials has been carried out over a two year period on the base heat shield of the Delta Clipper (DC-X and DC-XA), as well on a body flap. The purpose was to use the vehicle as a test bed for materials and more efficient repair or maintenance processes which would be potentially useful for application on new entry vehicles (i.e., X-33, RLV, planetary probes), as well as on the existing space shuttle orbiters. Panels containing Thermal Protection Systems (TPS) and/or structural materials were constructed either at NASA Ames Research Center or at McDonnell Douglas Aerospace (MDA) and attached between two of the four thrusters in the base heat shield of the DC-X or DC-XA. Three different panels were flown on DC-X flights 6, 7, and 8. A total of 7 panels were flown on DC-XA flights 1, 2, and 3. The panels constructed at Ames contained a variety of ceramic TPS including flexible blankets, tiles with high emissivity coatings, lightweight ceramic ablators and other ceramic composites. The MDS test panels consisted primarily of a variety of metallic composites. This report focuses on the ceramic TPS test results.
Yimam, Mesfin; Lee, Young-Chul; Jiao, Ping; Hong, Mei; Brownell, Lidia; Jia, Qi
2017-01-01
Background: Cellulite, characterized by changes in the skin morphology presented as dimpled or puckered skin appearance, is highly prevalent among postadolescent women. Cellulite management ranges from topical cream applications to invasive procedures. While some interventions showed improvements in physical appearances of affected areas, so far, none have reversed the condition to a full recovery. These unsuccessful measures signify the intricate nature of cellulite etiology highlighting its complexity leading to the possibility for a combination treatment approach to target multiple mechanisms. Materials and Methods: We screened our plant library for extracts that reduce cellular lipid accumulation, improve microcirculation, possess high total antioxidant capacity, significant anti-platelet aggregation, and anti-inflammatory activities using lipid accumulation assay in 3T3-L1 cells, Croton oil-induced hemorrhoid test in rats as a model for microcirculation, anti-platelet aggregation assay, nitric oxide (NO) inhibition assay, and 1,1-diphenyl-2-picrylhydrazyl assay. Results: Three known botanicals such as Rosemary officinalis, Annona squamosa and Zanthoxylum clava-herculis were identified as lead extracts in these tests. Treatment of 3T3 cell with A. squamosa at 1 μg/ml resulted in 68.8% reduction in lipid accumulation. In croton oil-induced hemorrhoid study, Z. clava-herculis reduced the recto-anus coefficient by 79.6% at 6 mg/kg indicating improvement in microcirculations. Similarly, R. officinalis caused inhibition of 82%, 71.8%, and 91.8% in platelet aggregation, NO production and free radical generation at 31.25 μg/ml, 6.2 μg/ml, and 40 μg/ml concentrations suggesting its anti-oxidant, and anti-inflammatory activities. Conclusions: Data depicted here suggest that formulation of these well-known botanicals at a specific ratio perhaps may yield a composition with a much wider spectrum of mechanisms of actions to impact the multiple pathways involved in
Power Strategy in DC/DC Converters to Increase Efficiency of Electrical Stimulators.
Aqueveque, Pablo; Acuña, Vicente; Saavedra, Francisco; Debelle, Adrien; Lonys, Laurent; Julémont, Nicolas; Huberland, François; Godfraind, Carmen; Nonclercq, Antoine
2016-06-13
Power efficiency is critical for electrical stimulators. Battery life of wearable stimulators and wireless power transmission in implanted systems are common limiting factors. Boost DC/DC converters are typically needed to increase the supply voltage of the output stage. Traditionally, boost DC/DC converters are used with fast control to regulate the supply voltage of the output. However, since stimulators are acting as current sources, such voltage regulation is not needed. Banking on this, this paper presents a DC/DC conversion strategy aiming to increase power efficiency. It compares, in terms of efficiency, the traditional use of boost converters to two alternatives that could be implemented in future hardware designs.
Novel bidirectional DC-DC converters based on the three-state switching cell
NASA Astrophysics Data System (ADS)
da Silva Júnior, José Carlos; Robles Balestero, Juan Paulo; Lessa Tofoli, Fernando
2016-05-01
It is well known that there is an increasing demand for bidirectional DC-DC converters for applications that range from renewable energy sources to electric vehicles. Within this context, this work proposes novel DC-DC converter topologies that use the three-state switching cell (3SSC), whose well-known advantages over conventional existing structures are ability to operate at high current levels, while current sharing is maintained by a high frequency transformer; reduction of cost and dimensions of magnetics; improved distribution of losses, with consequent increase of global efficiency and reduction of cost associated to the need of semiconductors with lower current ratings. Three distinct topologies can be derived from the 3SSC: one DC-DC converter with reversible current characteristic able to operate in the first and second quadrants; one DC-DC converter with reversible voltage characteristic able to operate in the first and third quadrants and one DC-DC converter with reversible current and voltage characteristics able to operate in four quadrants. Only the topology with bidirectional current characteristic is analysed in detail in terms of the operating stages in both nonoverlapping and overlapping modes, while the design procedure of the power stage elements is obtained. In order to validate the theoretical assumptions, an experimental prototype is also implemented, so that relevant issues can be properly discussed.
High power density dc/dc converter: Component selection and design
NASA Technical Reports Server (NTRS)
Divan, Deepakraj M.
1989-01-01
Further work pertaining to design considerations for the new high power, high frequency dc/dc converters is discussed. The goal of the project is the development of high power, high power density dc/dc converters at power levels in the multi-kilowatt to megawatt range for aerospace applications. The prototype converter is rated for 50 kW at a switching frequency of 50 kHz, with an input voltage of 200 Vdc and an output of 2000 Vdc. The overall power density must be in the vicinity of 0.2 to 0.3 kg/kW.
A state-trajectory control law for dc-to-dc converters
NASA Technical Reports Server (NTRS)
Burns, W. W., III; Wilson, T. G.
1978-01-01
Mathematical representations of a state-plane switching boundary employed in a state-trajectory control law for dc-to-dc converters are derived. Several levels of approximation to the switching boundary equations are presented, together with an evaluation of the effects of nonideal operating characteristics of converter power stage components on the shape and location of the boundary and the behavior of a system controlled by it. Digital computer simulations of dc-to-dc converters operating in conjunction with each of these levels of control are presented and evaluated with respect to changes in transient and steady-state performance.
Kwon, Eun-Bin; Kang, Myung-Ji; Kim, Soo-Yeon; Lee, Yong-Moon; Lee, Mi-Kyeong; Yuk, Heung Joo; Ryu, Hyung Won; Lee, Su Ui
2018-01-01
Zanthoxylum ailanthoides (ZA) has been used as folk medicines in East Asian and recently reported to have several bioactivity; however, the studies of ZA on the regulation of triacylglycerol (TG) biosynthesis have not been elucidated yet. In this study, we examined whether the methanol extract of ZA (ZA-M) could reduce oleic acid- (OA-) induced intracellular lipid accumulation and confirmed its mode of action in HepG2 cells. ZA-M was shown to promote the phosphorylation of AMPK and its upstream LKB1, followed by reduction of lipogenic gene expressions. As a result, treatment of ZA-M blocked de novo TG biosynthesis and subsequently mitigated intracellular neutral lipid accumulation in HepG2 cells. ZA-M also inhibited OA-induced production of reactive oxygen species (ROS) and TNF-α, suggesting that ZA-M possess the anti-inflammatory feature in fatty acid over accumulated condition. Taken together, these results suggest that ZA-M attenuates OA-induced lipid accumulation and inflammation through the activation of LKB1/AMPK signaling pathway in HepG2 cells. PMID:29507591
Kwon, Eun-Bin; Kang, Myung-Ji; Kim, Soo-Yeon; Lee, Yong-Moon; Lee, Mi-Kyeong; Yuk, Heung Joo; Ryu, Hyung Won; Lee, Su Ui; Oh, Sei-Ryang; Moon, Dong-Oh; Lee, Hyun-Sun; Kim, Mun-Ock
2018-01-01
Zanthoxylum ailanthoides (ZA) has been used as folk medicines in East Asian and recently reported to have several bioactivity; however, the studies of ZA on the regulation of triacylglycerol (TG) biosynthesis have not been elucidated yet. In this study, we examined whether the methanol extract of ZA (ZA-M) could reduce oleic acid- (OA-) induced intracellular lipid accumulation and confirmed its mode of action in HepG2 cells. ZA-M was shown to promote the phosphorylation of AMPK and its upstream LKB1, followed by reduction of lipogenic gene expressions. As a result, treatment of ZA-M blocked de novo TG biosynthesis and subsequently mitigated intracellular neutral lipid accumulation in HepG2 cells. ZA-M also inhibited OA-induced production of reactive oxygen species (ROS) and TNF- α , suggesting that ZA-M possess the anti-inflammatory feature in fatty acid over accumulated condition. Taken together, these results suggest that ZA-M attenuates OA-induced lipid accumulation and inflammation through the activation of LKB1/AMPK signaling pathway in HepG2 cells.
Bidirectional DC-DC conversion device use at system of urban electric transport
NASA Astrophysics Data System (ADS)
Vilberger, M. E.; Vislogusov, D. P.; Kotin, D. A.; Kulekina, A. V.
2017-10-01
The paper considers questions of energy storage devices used in electric transport, especially in the electric traction drive of a trolley bus, in order to provide an autonomous motion, overhead system’s load leveling and energy recovering. For efficiency of the proposed system, a bidirectional DC-DC converter is used. During the simulation, regulation characteristics of the bidirectional DC-DC converters were obtained.
NASA Technical Reports Server (NTRS)
Schwab, J. R.
1979-01-01
Performance data obtained through experimental testing of a 22.4 kW traction motor using two types of excitation are presented. Ripple free dc from a motor-generator set for baseline data and pulse width modulated dc as supplied by a battery pack and chopper controller were used for excitation. For the same average values of input voltage and current, the motor power output was independent of the type of excitation. However, at the same speeds, the motor efficiency at low power output (corresponding to low duty cycle of the controller) was 5 to 10 percentage points lower on chopped dc than on ripple free dc. The chopped dc locked-rotor torque was approximately 1 to 3 percent greater than the ripple free dc torque for the same average current.
Block clustering based on difference of convex functions (DC) programming and DC algorithms.
Le, Hoai Minh; Le Thi, Hoai An; Dinh, Tao Pham; Huynh, Van Ngai
2013-10-01
We investigate difference of convex functions (DC) programming and the DC algorithm (DCA) to solve the block clustering problem in the continuous framework, which traditionally requires solving a hard combinatorial optimization problem. DC reformulation techniques and exact penalty in DC programming are developed to build an appropriate equivalent DC program of the block clustering problem. They lead to an elegant and explicit DCA scheme for the resulting DC program. Computational experiments show the robustness and efficiency of the proposed algorithm and its superiority over standard algorithms such as two-mode K-means, two-mode fuzzy clustering, and block classification EM.
Efficient Visible Light Communication Transmitters Based on Switching-Mode dc-dc Converters.
Rodríguez, Juan; Lamar, Diego G; Aller, Daniel G; Miaja, Pablo F; Sebastián, Javier
2018-04-07
Visible light communication (VLC) based on solid-state lighting (SSL) is a promising option either to supplement or to substitute existing radio frequency (RF) wireless communication in indoor environments. VLC systems take advantage of the fast modulation of the visible light that light emitting diodes (LEDs) enable. The switching-mode dc-to-dc converter (SMC dc-dc ) must be the cornerstone of the LED driver of VLC transmitters in order to incorporate the communication functionality into LED lighting, keeping high power efficiency. However, the new requirements related to the communication, especially the high bandwidth that the LED driver must achieve, converts the design of the SMC dc-dc into a very challenging task. In this work, three different methods for achieving such a high bandwidth with an SMC dc-dc are presented: increasing the order of the SMC dc-dc output filter, increasing the number of voltage inputs, and increasing the number of phases. These three strategies are combinable and the optimum design depends on the particular VLC application, which determines the requirements of the VLC transmitter. As an example, an experimental VLC transmitter based on a two-phase buck converter with a fourth-order output filter will demonstrate that a bandwidth of several hundred kilohertz (kHz) can be achieved with output power levels close to 10 W and power efficiencies between 85% and 90%. In conclusion, the design strategy presented allows us to incorporate VLC into SSL, achieving high bit rates without damaging the power efficiency of LED lighting.
Wang, Ziming; Ding, Lan; Li, Tiechun; Zhou, Xin; Wang, Lu; Zhang, Hanqi; Liu, Li; Li, Ying; Liu, Zhihong; Wang, Hongju; Zeng, Hong; He, Hui
2006-01-13
Solvent-free microwave extraction (SFME) is a recently developed green technique which is performed in atmospheric conditions without adding any solvent or water. SFME has already been applied to extraction of essential oil from fresh plant materials or dried materials prior moistened. The essential oil is evaporated by the in situ water in the plant materials. In this paper, it was observed that an improved SFME, in which a kind of microwave absorption solid medium, such as carbonyl iron powders (CIP), was added and mixed with the sample, can be applied to extraction of essential oil from the dried plant materials without any pretreatment. Because the microwave absorption capacity of CIP is much better than that of water, the extraction time while using the improved SFME is no more than 30 min using a microwave power of 85 W. Compared to the conventional SFME, the advantages of improved SFME were to speed up the extraction rate and need no pretreatment. Improved SFME has been compared with conventional SFME, microwave-assisted hydrodistillation (MAHD) and conventional hydrodistillation (HD) for the extraction of essential oil from dried Cuminum cyminum L. and Zanthoxylum bungeanum Maxim. By using GC-MS system the compositions of essential oil extracted by applying four kinds of extraction methods were identified. There was no obvious difference in the quality of essential oils obtained by the four kinds of extraction methods.
Tavares, Luciana de C.; Zanon, Graciane; Weber, Andréia D.; Neto, Alexandre T.; Mostardeiro, Clarice P.; Da Cruz, Ivana B. M.; Oliveira, Raul M.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
2014-01-01
Zanthoxylum rhoifolium (Rutaceae) is a plant alkaloid that grows in South America and has been used in Brazilian traditional medicine for the treatment of different health problems. The present study was designed to evaluate the antimicrobial activity of the steam bark crude methanol extract, fractions, and pure alkaloids of Z. rhoifolium. Its stem bark extracts exhibited a broad spectrum of antimicrobial activity, ranging from 12.5 to 100 µg/mL using bioautography method, and from 125 to 500 µg/mL in the microdilution bioassay. From the dichloromethane basic fraction, three furoquinoline alkaloids (1–3), and nine benzophenanthridine alkaloids (4–12) were isolated and the antimicrobial activity of the benzophenanthridine alkaloids is discussed in terms of structure-activity relationships. The alkaloid with the widest spectrum of activity was chelerythrine (10), followed by avicine (12) and dihydrochelerythrine (4). The minimal inhibitory concentrations of chelerythrine, of 1.50 µg/mL for all bacteria tested, and between 3.12 and 6.25 µg/mL for the yeast tested, show this compound to be a more powerful antimicrobial agent when compared with the other active alkaloids isolated from Z. rhoifolium. To verify the potential importance of the methylenedioxy group (ring A) of these alkaloids, chelerythrine was selected to represent the remainder of the benzophenanthridine alkaloids isolated in this work and was subjected to a demethylation reaction giving derivative 14. Compared to chelerythrine, the derivative (14) was less active against the tested bacteria and fungi. Kinetic measurements of the bacteriolytic activities of chelerythrine against the bacteria Bacillus subtilis (Gram-positive) and Escherichia coli (Gram-negative) were determined by optical density based on real time assay, suggesting that its mechanism of action is not bacteriolytic. The present study did not detect hemolytic effects of chelerythrine on erythrocytes and found a protective effect
Cabral, Vanessa; Luo, Xuan; Junqueira, Elisabete; Costa, Sofia S; Mulhovo, Silva; Duarte, Aida; Couto, Isabel; Viveiros, Miguel; Ferreira, Maria-José U
2015-04-15
Six compounds (1-6), isolated from the methanol extract of the roots of the African medicinal plant Zanthoxylum capense Thunb. (Rutaceae), and seven ester derivatives (7-13) were evaluated for their antibacterial activities and modulatory effects on the MIC of antibiotics (erythromycin, oxacillin, and tetracycline) and ethidium bromide (EtBr) against a Staphylococcus aureus reference strain (ATCC 6538). Using the same model, compounds 1-13 were also assessed for their potential as efflux pump inhibitors by a fluorometric assay that measures the accumulation of the broad range efflux pump substrate EtBr. Compounds 8 and 11 were further evaluated for their antibacterial, modulatory and EtBr accumulation effects against four additional S. aureus strains, which included two clinical methicillin-resistant S. aureus (MRSA) strains. Compounds (1-13) have not shown antibacterial activity at the concentration ranges tested. When evaluated against S. aureus ATCC 6538, oxychelerythrine (1) a benzophenanthridine alkaloid, showed the highest modulatory activity enhancing the susceptibility of this strain to all the tested antibiotics from two to four-fold. Ailanthoidiol diacetate (8) and ailanthoidiol di-2-ethylbutanoate (11) were also good modulators when combined with EtBr, increasing the bacteria susceptibility by four and two-fold, respectively. In the EtBr accumulation assay, using ATCC 6538 strain, the phenylpropanoid (+)-ailanthoidiol (6) and most of its ester derivatives (8-11) exhibited higher activity than the positive control verapamil. The highest effects were found for compounds 8 and 11 that also increased the accumulation of EtBr, using S. aureus ATCC 25923 as model. Furthermore, both compounds (8, 11) were able to enhance the ciprofloxacin activity against the MRSA clinical strains tested, causing a reduction of the antibiotic MIC values from two to four-fold. The EtBr accumulation assay revealed that this modulation activity was not due to an inhibition of
Analysis of high voltage step-up nonisolated DC-DC boost converters
NASA Astrophysics Data System (ADS)
Alisson Alencar Freitas, Antônio; Lessa Tofoli, Fernando; Junior, Edilson Mineiro Sá; Daher, Sergio; Antunes, Fernando Luiz Marcelo
2016-05-01
A high voltage step-up nonisolated DC-DC converter based on coupled inductors suitable to photovoltaic (PV) systems applications is proposed in this paper. Considering that numerous approaches exist to extend the voltage conversion ratio of DC-DC converters that do not use transformers, a detailed comparison is also presented among the proposed converter and other popular topologies such as the conventional boost converter and the quadratic boost converter. The qualitative analysis of the coupled-inductor-based topology is developed so that a design procedure can be obtained, from which an experimental prototype is implemented to validate the theoretical assumptions.
DC-DC power converter research for Orbiter/Station power exchange
NASA Technical Reports Server (NTRS)
Ehsani, M.
1993-01-01
This project was to produce innovative DC-DC power converter concepts which are appropriate for the power exchange between the Orbiter and the Space Station Freedom (SSF). The new converters must interface three regulated power buses on SSF, which are at different voltages, with three fuel cell power buses on the Orbiter which can be at different voltages and should be tracked independently. Power exchange is to be bi-directional between the SSF and the Orbiter. The new converters must satisfy the above operational requirements with better weight, volume, efficiency, and reliability than is available from the present conventional technology. Two families of zero current DC-DC converters were developed and successfully adapted to this application. Most of the converters developed are new and are presented.
AC/DC Smart Control And Power Sharing of DC Distribution Systems
2012-02-10
system losses will decrease since the semiconductor losses due to switching in converter are reduced. The use of DC power systems to supply...cells yield variable DC voltage. In stand-alone systems , in order to be able to make full use of the generated power and to feed the loads, a controlled...alternate sources connected to the DC Distribution System
West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection.
Davis, Carl W; Nguyen, Hai-Yen; Hanna, Sheri L; Sánchez, Melissa D; Doms, Robert W; Pierson, Theodore C
2006-02-01
The C-type lectins DC-SIGN and DC-SIGNR bind mannose-rich glycans with high affinity. In vitro, cells expressing these attachment factors efficiently capture, and are infected by, a diverse array of appropriately glycosylated pathogens, including dengue virus. In this study, we investigated whether these lectins could enhance cellular infection by West Nile virus (WNV), a mosquito-borne flavivirus related to dengue virus. We discovered that DC-SIGNR promoted WNV infection much more efficiently than did DC-SIGN, particularly when the virus was grown in human cell types. The presence of a single N-linked glycosylation site on either the prM or E glycoprotein of WNV was sufficient to allow DC-SIGNR-mediated infection, demonstrating that uncleaved prM protein present on a flavivirus virion can influence viral tropism under certain circumstances. Preferential utilization of DC-SIGNR was a specific property conferred by the WNV envelope glycoproteins. Chimeras between DC-SIGN and DC-SIGNR demonstrated that the ability of DC-SIGNR to promote WNV infection maps to its carbohydrate recognition domain. WNV virions and subviral particles bound to DC-SIGNR with much greater affinity than DC-SIGN. We believe this is the first report of a pathogen interacting more efficiently with DC-SIGNR than with DC-SIGN. Our results should lead to the discovery of new mechanisms by which these well-studied lectins discriminate among ligands.
Sliding-mode control of single input multiple output DC-DC converter
NASA Astrophysics Data System (ADS)
Zhang, Libo; Sun, Yihan; Luo, Tiejian; Wan, Qiyang
2016-10-01
Various voltage levels are required in the vehicle mounted power system. A conventional solution is to utilize an independent multiple output DC-DC converter whose cost is high and control scheme is complicated. In this paper, we design a novel SIMO DC-DC converter with sliding mode controller. The proposed converter can boost the voltage of a low-voltage input power source to a controllable high-voltage DC bus and middle-voltage output terminals, which endow the converter with characteristics of simple structure, low cost, and convenient control. In addition, the sliding mode control (SMC) technique applied in our converter can enhance the performances of a certain SIMO DC-DC converter topology. The high-voltage DC bus can be regarded as the main power source to the high-voltage facility of the vehicle mounted power system, and the middle-voltage output terminals can supply power to the low-voltage equipment on an automobile. In the respect of control algorithm, it is the first time to propose the SMC-PID (Proportion Integration Differentiation) control algorithm, in which the SMC algorithm is utilized and the PID control is attended to the conventional SMC algorithm. The PID control increases the dynamic ability of the SMC algorithm by establishing the corresponding SMC surface and introducing the attached integral of voltage error, which endow the sliding-control system with excellent dynamic performance. At last, we established the MATLAB/SIMULINK simulation model, tested performance of the system, and built the hardware prototype based on Digital Signal Processor (DSP). Results show that the sliding mode control is able to track a required trajectory, which has robustness against the uncertainties and disturbances.
Sliding-mode control of single input multiple output DC-DC converter.
Zhang, Libo; Sun, Yihan; Luo, Tiejian; Wan, Qiyang
2016-10-01
Various voltage levels are required in the vehicle mounted power system. A conventional solution is to utilize an independent multiple output DC-DC converter whose cost is high and control scheme is complicated. In this paper, we design a novel SIMO DC-DC converter with sliding mode controller. The proposed converter can boost the voltage of a low-voltage input power source to a controllable high-voltage DC bus and middle-voltage output terminals, which endow the converter with characteristics of simple structure, low cost, and convenient control. In addition, the sliding mode control (SMC) technique applied in our converter can enhance the performances of a certain SIMO DC-DC converter topology. The high-voltage DC bus can be regarded as the main power source to the high-voltage facility of the vehicle mounted power system, and the middle-voltage output terminals can supply power to the low-voltage equipment on an automobile. In the respect of control algorithm, it is the first time to propose the SMC-PID (Proportion Integration Differentiation) control algorithm, in which the SMC algorithm is utilized and the PID control is attended to the conventional SMC algorithm. The PID control increases the dynamic ability of the SMC algorithm by establishing the corresponding SMC surface and introducing the attached integral of voltage error, which endow the sliding-control system with excellent dynamic performance. At last, we established the MATLAB/SIMULINK simulation model, tested performance of the system, and built the hardware prototype based on Digital Signal Processor (DSP). Results show that the sliding mode control is able to track a required trajectory, which has robustness against the uncertainties and disturbances.
Zuo, Guo-Ying; Wang, Chun-Juan; Han, Jun; Li, Yu-Qing; Wang, Gen-Chun
2016-12-15
Methicillin-resistant Staphylococcus aureus (MRSA) poses a serious therapeutic challenge in current clinic and new drug development. Natural coumarins have diverse bioactivities and the potential of resistance modifying effects. This study is to present in-depth evaluations of in vitro antimicrobial activities of four natural coumarins 5-geranyloxy-7-methoxycoumarin (Gm, 1), (5,7-dimethoxy-8-prenyloxycoumarin (artanin, Ar, 2)), isopimpinellin (Is, 3) and phellopterin (Ph, 4) from Zanthoxylum nitidum (Roxb.) DC. (Rutaceae) extracts, focusing on their potential restoration the activity of conventional antibacterial agents against clinical MRSA strains. Bioactivity-guided fractionation and spectral analyses were used to isolate the coumarins and identify the structures, respectively. The double broth microdilution method was used to assay the coumarins' alone activity. The classic checkerboard microdilution and dynamic time-killing methods were used to evaluate combinatory effects. The four plant coumarins Gm (1), Ar (2), Is (3) and Ph (4) were isolated and identified from Z. nitidum extracts. Coumarins 1-4 displayed promising inhibition against both MSSA and MRSA with minimal inhibitory concentrations (MICs) of 8-64µg/ml, but very weak against Gram-negative pathogen and yeast with MICs of 256 to ≥1024µg/ml. The geranyloxy and prenyloxy substitutions showed to be more active than the methoxy substitution on the coumarin skeletons. 1-4 also showing different extent of synergism with a total of eight conventional antibacterial agents, i.e. chloramphenicol (CL), gentamicin (CN), fosfomycin (FF), levofloxacin (LE), minocycline (MI), piperacillin/tazobactam (P/T), teicoplanin (TE) and vancomycin (VA) against ten clinical MRSA strains. Four to ten of the tested MRSA strains showed bacteriostatic synergy in the eleven combinations. The anti-MRSA modifying effects were related to different arrangement in the combinations with fractional inhibitory concentration indices
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-07
... Airworthiness Limitations inspections (ALIs). This AD results from a design review of the fuel tank systems. We... inspections (ALIs). Relevant Service Information We reviewed Boeing DC-8 Special Compliance Item Report, MDC..., Revision C, dated January 5, 2010; or Revision D, dated June 9, 2010. (2) ALI 30-1 ``DC-8 Pneumatic System...
Synthesis and implementation of state-trajectory control law for dc-to-dc converters
NASA Technical Reports Server (NTRS)
Burns, W. W., III; Huffman, S. D.; Wilson, T. G.; Owen, H. A., Jr.
1977-01-01
Mathematical representations of a state-plane switching boundary employed in a state-trajectory control law for dc-to-dc converters are derived. Two approaches to implementing the control law are discussed; one approach employs a digital processor and the other uses analog computational circuits. Performance characteristics of experimental voltage step-up dc-to-dc converters operating under the control of each of these implementations are presented.
Auxiliary resonant DC tank converter
Peng, Fang Z.
2000-01-01
An auxiliary resonant dc tank (ARDCT) converter is provided for achieving soft-switching in a power converter. An ARDCT circuit is coupled directly across a dc bus to the inverter to generate a resonant dc bus voltage, including upper and lower resonant capacitors connected in series as a resonant leg, first and second dc tank capacitors connected in series as a tank leg, and an auxiliary resonant circuit comprising a series combination of a resonant inductor and a pair of auxiliary switching devices. The ARDCT circuit further includes first clamping means for holding the resonant dc bus voltage to the dc tank voltage of the tank leg, and second clamping means for clamping the resonant dc bus voltage to zero during a resonant period. The ARDCT circuit resonantly brings the dc bus voltage to zero in order to provide a zero-voltage switching opportunity for the inverter, then quickly rebounds the dc bus voltage back to the dc tank voltage after the inverter changes state. The auxiliary switching devices are turned on and off under zero-current conditions. The ARDCT circuit only absorbs ripples of the inverter dc bus current, thus having less current stress. In addition, since the ARDCT circuit is coupled in parallel with the dc power supply and the inverter for merely assisting soft-switching of the inverter without participating in real dc power transmission and power conversion, malfunction and failure of the tank circuit will not affect the functional operation of the inverter; thus a highly reliable converter system is expected.
Dc-To-Dc Converter Uses Reverse Conduction Of MOSFET's
NASA Technical Reports Server (NTRS)
Gruber, Robert P.; Gott, Robert W.
1991-01-01
In modified high-power, phase-controlled, full-bridge, pulse-width-modulated dc-to-dc converters, switching devices power metal oxide/semiconductor field-effect transistors (MOSFET's). Decreases dissipation of power during switching by eliminating approximately 0.7-V forward voltage drop in anti-parallel diodes. Energy-conversion efficiency increased.
Development of a DC-DC conversion powering scheme for the CMS Phase-1 pixel upgrade
NASA Astrophysics Data System (ADS)
Feld, L.; Fimmers, C.; Karpinski, W.; Klein, K.; Lipinski, M.; Preuten, M.; Rauch, M.; Rittich, D.; Sammet, J.; Wlochal, M.
2014-01-01
A novel powering scheme based on the DC-DC conversion technique will be exploited to power the CMS Phase-1 pixel detector. DC-DC buck converters for the CMS pixel project have been developed, based on the AMIS5 ASIC designed by CERN. The powering system of the Phase-1 pixel detector is described and the performance of the converter prototypes is detailed, including power efficiency, stability of the output voltage, shielding, and thermal management. Results from a test of the magnetic field tolerance of the DC-DC converters are reported. System tests with pixel modules using many components of the future pixel barrel system are summarized. Finally first impressions from a pre-series of 200 DC-DC converters are presented.
A Study of 4-level DC-DC Boost Inverter with Passive Component Reduction Consideration
NASA Astrophysics Data System (ADS)
Kasiran, A. N.; Ponniran, A.; Harimon, M. A.; Hamzah, H. H.
2018-04-01
This study is to analyze design principles of boost inductor and capacitor used in the 4-level DC-DC boost converter to realize size reduction of passive component referring to their attributes. The important feature of this circuit is that most of the boost-up energy is transferred from the capacitor-clamped to the output side which the small inductance can be used at the input side. The inductance of the boost inductor is designed by referring the inductor current ripple. On the other hand, the capacitance of the capacitor-clamped is designed by considering voltage stress on semiconductor devices and also the used switching frequency. Besides that, according to the design specifications, the required inductance in 4-level DC-DC boost converter is decreased compared to a conventional conventional DC-DC boost converter. Meanwhile, voltage stress on semiconductor device is depending on the maximum voltage ripple of the capacitor-clamped. A 50 W 4-level DC-DC boost converter prototype has been constructed. The results show that the inductor current ripple was 1.15 A when the inductors, 1 mH and 0.11 mH were used in the conventional and 4-level DC-DC boost converters, respectively. Thus, based on the experimental results, it shows that the reduction of passive components by referring to their attributes in 4-level DC-DC boost converter is achieved. Moreover, the decreasing of voltage stress on the semiconductor devices is an advantage for the selection of low ON-resistance of the devices which will contribute to the reduction of the semiconductor conduction loss. The integration result of boost converter and H-bridge inverter is also shown.
A Nonlinear Digital Control Solution for a DC/DC Power Converter
NASA Technical Reports Server (NTRS)
Zhu, Minshao
2002-01-01
A digital Nonlinear Proportional-Integral-Derivative (NPID) control algorithm was proposed to control a 1-kW, PWM, DC/DC, switching power converter. The NPID methodology is introduced and a practical hardware control solution is obtained. The design of the controller was completed using Matlab (trademark) Simulink, while the hardware-in-the-loop testing was performed using both the dSPACE (trademark) rapid prototyping system, and a stand-alone Texas Instruments (trademark) Digital Signal Processor (DSP)-based system. The final Nonlinear digital control algorithm was implemented and tested using the ED408043-1 Westinghouse DC-DC switching power converter. The NPID test results are discussed and compared to the results of a standard Proportional-Integral (PI) controller.
Guidelines for Reliable DC/DC Converters for Space Use
NASA Technical Reports Server (NTRS)
Plante, Jeannette; Shue, Jack
2008-01-01
NESC saw the need to study the persistent failure of DC/DC Converters during ground testing and in flight, motivated investigation of causes and mitigation options. Research indicated misapplication and device quality to be root causes. The study took 20 months. Team included multiple NASA Centers : JPL, JSC, MSFC, GSFC Project Background
On the modelling of linear-assisted DC-DC voltage regulators for photovoltaic solar energy systems
NASA Astrophysics Data System (ADS)
Martínez-García, Herminio; García-Vílchez, Encarna
2017-11-01
This paper shows the modelling of linear-assisted or hybrid (linear & switching) DC/DC voltage regulators. In this kind of regulators, an auxiliary linear regulator is used, which objective is to cancel the ripple at the output voltage and provide fast responses for load variations. On the other hand, a switching DC/DC converter, connected in parallel with the linear regulator, allows to supply almost the whole output current demanded by the load. The objective of this topology is to take advantage of the suitable regulation characteristics that series linear voltage regulators have, but almost achieving the high efficiency that switching DC/DC converters provide. Linear-assisted DC/DC regulators are feedback systems with potential instability. Therefore, their modelling is mandatory in order to obtain design guidelines and assure stability of the implemented power supply system.
Test Results of Selected Commercial DC/DC Converters under Cryogenic Temperatures - A Digest
NASA Technical Reports Server (NTRS)
Patterson, Richard; Hammoud, Ahmad
2010-01-01
DC/DC converters are widely used in space power systems in the areas of power management and distribution, signal conditioning, and motor control. Design of DC/DC converters to survive cryogenic temperatures will improve the power system performance, simplify design, and reduce development and launch costs. In this work, the performance of nine COTS modular, low-tomedium power DC/DC converters was investigated under cryogenic temperatures. The converters were evaluated in terms of their output regulation, efficiency, and input and output currents. At a given temperature, these properties were obtained at various input voltages and at different load levels. A summary on the performance of the tested converters was given. More comprehensive testing and in-depth analysis of performance under long-term exposure to extreme temperatures are deemed necessary to establish the suitability of these and other devices for use in the harsh environment of space exploration missions.
NASA Technical Reports Server (NTRS)
Lukemire, Alan T. (Inventor)
1995-01-01
A pulse-width modulated DC-to-DC power converter including a first inductor, i.e. a transformer or an equivalent fixed inductor equal to the inductance of the secondary winding of the transformer, coupled across a source of DC input voltage via a transistor switch which is rendered alternately conductive (ON) and nonconductive (OFF) in accordance with a signal from a feedback control circuit is described. A first capacitor capacitively couples one side of the first inductor to a second inductor which is connected to a second capacitor which is coupled to the other side of the first inductor. A circuit load shunts the second capacitor. A semiconductor diode is additionally coupled from a common circuit connection between the first capacitor and the second inductor to the other side of the first inductor. A current sense transformer generating a current feedback signal for the switch control circuit is directly coupled in series with the other side of the first inductor so that the first capacitor, the second inductor and the current sense transformer are connected in series through the first inductor. The inductance values of the first and second inductors, moreover, are made identical. Such a converter topology results in a simultaneous voltsecond balance in the first inductance and ampere-second balance in the current sense transformer.
Pulsed-DC DBD Plasma Actuators
NASA Astrophysics Data System (ADS)
Duong, Alan; Corke, Thomas; Thomas, Flint
2017-11-01
A power system for dielectric barrier discharge (DBD) plasma actuators that utilizes a pulsed-DC waveform is presented. The plasma actuator arrangement is identical to most typical AC-DBD designs with staggered electrodes that are separated by a dielectric insulator. A key difference is that the pulsed-DC actuator utilizes a DC voltage source to drive the actuator instead of an AC voltage input. The DC source is supplied to both electrodes. The exposed electrode remains constant in time while the encapsulated electrode is periodically grounded for short instances then is allowed to rise to the source DC level. Further investigation of the pulsed-DC plasma actuator was conducted. Time-resolved velocity measurements were done to characterize the induced velocity field generated by the pulsed-DC plasma actuator. A model of the pulsed-DC plasma actuator is developed in LTspice for further study. The work presented are intended in developing a model to be used in CFD flow control simulations. NASA SBIR NNX14CC12C.
Su, Gui-Jia
2003-06-10
A multilevel DC link inverter and method for improving torque response and current regulation in permanent magnet motors and switched reluctance motors having a low inductance includes a plurality of voltage controlled cells connected in series for applying a resulting dc voltage comprised of one or more incremental dc voltages. The cells are provided with switches for increasing the resulting applied dc voltage as speed and back EMF increase, while limiting the voltage that is applied to the commutation switches to perform PWM or dc voltage stepping functions, so as to limit current ripple in the stator windings below an acceptable level, typically 5%. Several embodiments are disclosed including inverters using IGBT's, inverters using thyristors. All of the inverters are operable in both motoring and regenerating modes.
Chaos minimization in DC-DC boost converter using circuit parameter optimization
NASA Astrophysics Data System (ADS)
Sudhakar, N.; Natarajan, Rajasekar; Gourav, Kumar; Padmavathi, P.
2017-11-01
DC-DC converters are prone to several types of nonlinear phenomena including bifurcation, quasi periodicity, intermittency and chaos. These undesirable effects must be controlled for periodic operation of the converter to ensure the stability. In this paper an effective solution to control of chaos in solar fed DC-DC boost converter is proposed. Controlling of chaos is significantly achieved using optimal circuit parameters obtained through Bacterial Foraging Optimization Algorithm. The optimization renders the suitable parameters in minimum computational time. The obtained results are compared with the operation of traditional boost converter. Further the obtained results with BFA optimized parameter ensures the operations of the converter are within the controllable region. To elaborate the study of bifurcation analysis with optimized and unoptimized parameters are also presented.
Zero-voltage DC/DC converter with asymmetric pulse-width modulation for DC micro-grid system
NASA Astrophysics Data System (ADS)
Lin, Bor-Ren
2018-04-01
This paper presents a zero-voltage switching DC/DC converter for DC micro-grid system applications. The proposed circuit includes three half-bridge circuit cells connected in primary-series and secondary-parallel in order to lessen the voltage rating of power switches and current rating of rectifier diodes. Thus, low voltage stress of power MOSFETs can be adopted for high-voltage input applications with high switching frequency operation. In order to achieve low switching losses and high circuit efficiency, asymmetric pulse-width modulation is used to turn on power switches at zero voltage. Flying capacitors are used between each circuit cell to automatically balance input split voltages. Therefore, the voltage stress of each power switch is limited at Vin/3. Finally, a prototype is constructed and experiments are provided to demonstrate the circuit performance.
Radiation-Tolerant DC-DC Converters
NASA Technical Reports Server (NTRS)
Skutt, Glenn; Sable, Dan; Leslie, Leonard; Graham, Shawn
2012-01-01
A document discusses power converters suitable for space use that meet the DSCC MIL-PRF-38534 Appendix G radiation hardness level P classification. A method for qualifying commercially produced electronic parts for DC-DC converters per the Defense Supply Center Columbus (DSCC) radiation hardened assurance requirements was developed. Development and compliance testing of standard hybrid converters suitable for space use were completed for missions with total dose radiation requirements of up to 30 kRad. This innovation provides the same overall performance as standard hybrid converters, but includes assurance of radiation- tolerant design through components and design compliance testing. This availability of design-certified radiation-tolerant converters can significantly reduce total cost and delivery time for power converters for space applications that fit the appropriate DSCC classification (30 kRad).
Light weight, high power, high voltage dc/dc converter technologies
NASA Technical Reports Server (NTRS)
Kraus, Robert; Myers, Ira; Baumann, Eric
1990-01-01
Power-conditioning weight reductions by orders of magnitude will be required to enable the megawatt-power-level space systems envisioned by the Strategic Defense Initiative, the Air Force, and NASA. An interagency program has been initiated to develop an 0.1-kg/kW dc/dc converter technology base for these future space applications. Three contractors are in the first phase of a competitive program to develop a megawatt dc/dc converter. Researchers at NASA Lewis Research Center are investigating innovative converter topology control. Three different converter subsystems based on square wave, resonant, and super-resonant topologies are being designed. The components required for the converter designs cover a wide array of technologies. Two different switches, one semiconductor and the other gas, are under development. Issues related to thermal management and material reliability for inductors, transformers, and capacitors are being investigated in order to maximize power density. A brief description of each of the concepts proposed to meet the goals of this program is presented.
A miniature transformer/dc-dc converter for implantable medical devices
NASA Astrophysics Data System (ADS)
Mohammed, Osama A.; Jones, W. Kinzy
1988-11-01
This paper presents a new technique for the design of a miniature dc-dc converter used in energy producing implantable devices such as defibrillators and advanced pacemakers. This converter is inserted in such a device and is used to boost the voltage from a low voltage implanted battery to high voltage energy storage capacitors in a short period of time. The stored energy is then delivered, when needed, through an energy delivery circuit in order to stimulate or defibrillate the heart. The converter takes the form of a flyback topology which includes a miniature transformer and a specialized control circuit. The transformer was designed using a new numerical synthesis method which utilizes finite elements and dynamic programming for predicting the geometries of the transformer's magnetic circuit. The final transformer design satisfied the performance criteria and provided means for selecting the converter components. The obtained performance results for the transformer and the dc-dc converter were in excellent agreement with laboratory performance tests.
Wang, Cheng-Fang; Yang, Kai; You, Chun-Xue; Zhang, Wen-Juan; Guo, Shan-Shan; Geng, Zhu-Feng; Du, Shu-Shan; Wang, Yong-Yan
2015-05-04
This work aimed to investigate chemical composition of essential oils obtained from Zanthoxylum dissitum leaves and roots and their insecticidal activities against several stored product pests, namely the cigarette beetle (Lasioderma serricorne), red flour beetle (Tribolium castaneum) and black carpet beetle (Attagenus piceus). The analysis by GC-MS of the essential oils allowed the identification of 28 and 22 components, respectively. It was found that sesquiterpenoids comprised a fairly high portion of the two essential oils, with percentages of 74.0% and 80.9% in the leaves and roots, respectively. The main constituents identified in the essential oil of Z. dissitum leaves were δ-cadinol (12.8%), caryophyllene (12.7%), β-cubebene (7.9%), 4-terpineol (7.5%) and germacrene D-4-ol (5.7%), while humulene epoxide II (29.4%), caryophyllene oxide (24.0%), diepicedrene-1-oxide (10.7%) and Z,Z,Z-1,5,9,9-tetramethyl-1,4,7-cycloundecatriene (8.7%) were the major components in the essential oil of Z. dissitum roots. The insecticidal activity results indicated that the essential oil of Z. dissitum roots exhibited moderate contact toxicity against three species of storage pests, L. serricorne,T. castaneum and A. piceus, with LD50 values of 13.8, 43.7 and 96.8 µg/adult, respectively.
Modeling and analysis of fractional order DC-DC converter.
Radwan, Ahmed G; Emira, Ahmed A; AbdelAty, Amr M; Azar, Ahmad Taher
2017-07-11
Due to the non-idealities of commercial inductors, the demand for a better model that accurately describe their dynamic response is elevated. So, the fractional order models of Buck, Boost and Buck-Boost DC-DC converters are presented in this paper. The detailed analysis is made for the two most common modes of converter operation: Continuous Conduction Mode (CCM) and Discontinuous Conduction Mode (DCM). Closed form time domain expressions are derived for inductor currents, voltage gain, average current, conduction time and power efficiency where the effect of the fractional order inductor is found to be strongly present. For example, the peak inductor current at steady state increases with decreasing the inductor order. Advanced Design Systems (ADS) circuit simulations are used to verify the derived formulas, where the fractional order inductor is simulated using Valsa Constant Phase Element (CPE) approximation and Generalized Impedance Converter (GIC). Different simulation results are introduced with good matching to the theoretical formulas for the three DC-DC converter topologies under different fractional orders. A comprehensive comparison with the recently published literature is presented to show the advantages and disadvantages of each approach. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-01
... Airworthiness Directives; McDonnell Douglas Corporation Model DC- 9-10 Series Airplanes, DC-9-30 Series Airplanes, DC-9-81 (MD-81) Airplanes, DC-9-82 (MD-82) Airplanes, DC-9-83 (MD-83) Airplanes, DC-9- 87 (MD-87... Building Ground Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC 20590, between 9 a.m. and...
A high voltage ratio and low ripple interleaved DC-DC converter for fuel cell applications.
Chang, Long-Yi; Chao, Kuei-Hsiang; Chang, Tsang-Chih
2012-01-01
This paper proposes a high voltage ratio and low ripple interleaved boost DC-DC converter, which can be used to reduce the output voltage ripple. This converter transfers the low DC voltage of fuel cell to high DC voltage in DC link. The structure of the converter is parallel with two voltage-doubler boost converters by interleaving their output voltages to reduce the voltage ripple ratio. Besides, it can lower the current stress for the switches and inductors in the system. First, the PSIM software was used to establish a proton exchange membrane fuel cell and a converter circuit model. The simulated and measured results of the fuel cell output characteristic curve are made to verify the correctness of the established simulation model. In addition, some experimental results are made to validate the effectiveness in improving output voltage ripple of the proposed high voltage ratio interleaved boost DC-DC converters.
DC Rocks! Using Place-Based Learning to Introduce Washington DC's K-12 Students to the Geosciences
NASA Astrophysics Data System (ADS)
Mayberry, G. C.; Mattietti, G. K.
2017-12-01
The Washington DC area has interesting geology and a multitude of agencies that deal with the geosciences, yet K-12 public school students in DC, most of whom are minorities, have limited exposure to the geosciences. Geoscience agencies in the DC area have a unique opportunity to address this by introducing the geosciences to local students who otherwise may not have such an opportunity, by highlighting the geology in the students' "backyard," and by leveraging partnerships among DC-based geoscience-related agencies. The USGS and George Mason University are developing a project called DC Rocks, which will give DC's students an exciting introduction into the world of geoscience with place-based learning opportunities that will make geoscience relevant to their lives and their futures. Both the need in DC and the potential for lasting impact are great; the geosciences have the lowest racial diversity of all the science, technology, engineering, and math (STEM) fields, 89% of students in DC public schools are minorities, and there is no dedicated geoscience curriculum in DC. DC Rocks aims to give these students early exposure to the earth sciences, and encourage them to consider careers in the profession. DC Rocks will work with partner agencies to apply several methods that are recommended by researchers to increase the participation of minority students in the geosciences, including providing profoundly positive experiences that spark interest in the geosciences (Levine et al., 2007); increasing students' sense of belonging in the geosciences (Huntoon, et al, 2016); and place-based teaching practices that emphasize the study of local sites (Semken, 2005), such as DC's Rock Creek Park. DC Rocks will apply these methods by coordinating local geoscientists and resources to provide real-world examples of the geosciences' impact on students' lives. Through the DC Rocks website, educators will be able to request geoscience-related resources such as class presentations by
A High Voltage Ratio and Low Ripple Interleaved DC-DC Converter for Fuel Cell Applications
Chang, Long-Yi; Chao, Kuei-Hsiang; Chang, Tsang-Chih
2012-01-01
This paper proposes a high voltage ratio and low ripple interleaved boost DC-DC converter, which can be used to reduce the output voltage ripple. This converter transfers the low DC voltage of fuel cell to high DC voltage in DC link. The structure of the converter is parallel with two voltage-doubler boost converters by interleaving their output voltages to reduce the voltage ripple ratio. Besides, it can lower the current stress for the switches and inductors in the system. First, the PSIM software was used to establish a proton exchange membrane fuel cell and a converter circuit model. The simulated and measured results of the fuel cell output characteristic curve are made to verify the correctness of the established simulation model. In addition, some experimental results are made to validate the effectiveness in improving output voltage ripple of the proposed high voltage ratio interleaved boost DC-DC converters. PMID:23365536
NASA Astrophysics Data System (ADS)
Crapo, Alan D.; Lloyd, Jerry D.
1991-03-01
Two motors have been designed and built for use with high-temperature superconductor (HTSC) materials. They are a homopolar dc motor that uses HTSC field windings and a brushless dc motor that uses bulk HTSC materials to trap flux in steel rotor poles. The HTSC field windings of the homopolar dc motor are designed to operate at 1000 A/sq cm in a 0.010-T field. In order to maximize torque in the homopolar dc motor, an iron magnetic circuit with small air gaps gives maximum flux for minimum Ampere turns in the field. A copper field winding version of the homopolar dc motor has been tested while waiting for 575 A turn HTSC coils. The trapped flux brushless dc motor has been built and is ready to test melt textured bulk HTSC rings that are currently being prepared. The stator of the trapped flux motor will impress a magnetic field in the steel rotor poles with warm HTSC bulk rings. The rings are then cooled to 77 K to trap the flux in the rotor. The motor can then operate as a brushless dc motor.
DC coupled Doppler radar physiological monitor.
Zhao, Xi; Song, Chenyan; Lubecke, Victor; Boric-Lubecke, Olga
2011-01-01
One of the challenges in Doppler radar systems for physiological monitoring is a large DC offset in baseband outputs. Typically, AC coupling is used to eliminate this DC offset. Since the physiological signals of interest include frequency content near DC, it is not desirable to simply use AC coupling on the radar outputs. While AC coupling effectively removes DC offset, it also introduces a large time delay and distortion. This paper presents the first DC coupled IQ demodulator printed circuit board (PCB) design and measurements. The DC coupling is achieved by using a mixer with high LO to RF port isolation, resulting in a very low radar DC offset on the order of mV. The DC coupled signals from the PCB radar system were successfully detected with significant LNA gain without saturation. Compared to the AC coupled results, the DC coupled results show great advantages of less signal distortion and more accurate rate estimation.
Application handbook for a Standardized Control Module (SCM) for DC-DC converters, volume 1
NASA Astrophysics Data System (ADS)
Lee, F. C.; Mahmoud, M. F.; Yu, Y.
1980-04-01
The standardized control module (SCM) was developed for application in the buck, boost and buck/boost DC-DC converters. The SCM used multiple feedback loops to provide improved input line and output load regulation, stable feedback control system, good dynamic transient response and adaptive compensation of the control loop for changes in open loop gain and output filter time constraints. The necessary modeling and analysis tools to aid the design engineer in the application of the SCM to DC-DC Converters were developed. The SCM functional block diagram and the different analysis techniques were examined. The average time domain analysis technique was chosen as the basic analytical tool. The power stage transfer functions were developed for the buck, boost and buck/boost converters. The analog signal and digital signal processor transfer functions were developed for the three DC-DC Converter types using the constant on time, constant off time and constant frequency control laws.
Application handbook for a Standardized Control Module (SCM) for DC-DC converters, volume 1
NASA Technical Reports Server (NTRS)
Lee, F. C.; Mahmoud, M. F.; Yu, Y.
1980-01-01
The standardized control module (SCM) was developed for application in the buck, boost and buck/boost DC-DC converters. The SCM used multiple feedback loops to provide improved input line and output load regulation, stable feedback control system, good dynamic transient response and adaptive compensation of the control loop for changes in open loop gain and output filter time constraints. The necessary modeling and analysis tools to aid the design engineer in the application of the SCM to DC-DC Converters were developed. The SCM functional block diagram and the different analysis techniques were examined. The average time domain analysis technique was chosen as the basic analytical tool. The power stage transfer functions were developed for the buck, boost and buck/boost converters. The analog signal and digital signal processor transfer functions were developed for the three DC-DC Converter types using the constant on time, constant off time and constant frequency control laws.
Application of Distributed DC/DC Electronics in Photovoltaic Systems
NASA Astrophysics Data System (ADS)
Kabala, Michael
In a typical residential, commercial or utility grade photovoltaic (PV) system, PV modules are connected in series and in parallel to form an array that is connected to a standard DC/AC inverter, which is then connected directly to the grid. This type of standard installation; however, does very little to maximize the energy output of the solar array if certain conditions exist. These conditions could include age, temperature, irradiance and other factors that can cause mismatch between PV modules in an array that severely cripple the output power of the system. Since PV modules are typically connected in series to form a string, the output of the entire string is limited by the efficiency of the weakest module. With PV module efficiencies already relatively low, it is critical to extract the maximum power out of each module in order to make solar energy an economically viable competitor to oil and gas. Module level DC/DC electronics with maximum power point (MPP) tracking solves this issue by decoupling each module from the string in order for the module to operate independently of the geometry and complexity of the surrounding system. This allows each PV module to work at its maximum power point by transferring the maximum power the module is able to deliver directly to the load by either boosting (stepping up) the voltage or bucking (stepping down) the voltage. The goal of this thesis is to discuss the development of a per-module DC/DC converter in order to maximize the energy output of a PV module and reduce the overall cost of the system by increasing the energy harvest.
NASA Astrophysics Data System (ADS)
Geetha, A.; Subramani, C.; Thamizh Thentral, T. M.; Krithika, V.; Usha, S.
2018-04-01
Non isolated Bidirectional DC-DC Converter (NIBDDC) is a good interface between DC source and inverter Fed induction motor drive. This paper deals with comparison between open loop and PI controlled Bidirectional DC to DC Converter Inverter System (BDDCIS). The modelling and control of BDDC is becomes an important issue. Open loop BDDCIS and closed loop PI controlled BDDCIS are designed, modelled and simulated using Matlab- simulink and their results are presented. The investigations indicate superior performance of PI controlled BDDCIS. The proposed BDDCIS has advantages like bidirectional power transfer ability, reduced hardware count and improved dynamic response.
Single-event burnout of n-p-n bipolar-junction transistors in hybrid DC/DC converters
NASA Astrophysics Data System (ADS)
Warren, K.; Roth, D.; Kinnison, J.; Pappalardo, R.
2002-12-01
Single-event-induced failure of the Lambda Advanced Analog AMF2805S DC/DC Converter has been traced to burnout of an n-p-n transistor in the MOSFET drive stage. The failures were observed during testing while in inhibit mode only. Modifications to prevent burnout of the drive stage were successfully employed. A discussion of the failure mechanism and consequences for DC/DC converter testing are presented.
Single Event Burnout in DC-DC Converters for the LHC Experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Claudio H. Rivetta et al.
High voltage transistors in DC-DC converters are prone to catastrophic Single Event Burnout in the LHC radiation environment. This paper presents a systematic methodology to analyze single event effects sensitivity in converters and proposes solutions based on de-rating input voltage and output current or voltage.
Chen, Kai; Chen, Zhe; Sun, Zhigang; Zhang, Zhuqing; Ding, Dongbing; Ren, Shuangyi; Zuo, Yunfei
2014-01-01
Background Colon cancer has always been diagnosed at a late stage, which is associated with poor prognosis. The currently used serum tumor markers CEA and CA19-9 display low sensitivity and specificity and may not have diagnostic value in early stage colon cancer. Thus, there is an urgent need to identify novel serum biomarkers for use in the early detection of colon cancer. Methods In this study, the expression of DC-SIGN and DC-SIGNR in serum was detected by enzyme-linked immunosorbent assay (ELISA). DC-SIGN and DC-SIGNR expression was detected in cancer tissues by immunohistochemistry (IHC). Results The level of sDC-SIGN was lower in patients than in the healthy controls, while the level of sDC-SIGNR in patients was higher than in the healthy controls. Both sDC-SIGN and sDC-SIGNR had diagnostic significances for cancer patients, and the combined diagnosis of these two markers was higher than both of them alone. Furthermore, there were significant differences between both sDC-SIGN and sDC-SIGNR in stage I/II patients and the healthy controls. Moreover, high sDC-SIGN level was accompanied with the long survival time. Additionally, DC-SIGNR was negative in the cancer foci and matched normal colon tissues but was weakly positive between the cancer foci. DC-SIGN staining was faint in matched normal colon tissues, strong in the tumor stroma and the invasive margin of colon cancer tissues, and negatively correlated with the sDC-SIGN level in serum from the same patient. Interestingly, the percent survival of patients with a DC-SIGN mean density of>0.001219 (the upper 95% confidence interval of matched normal colon tissues) was higher than for all other patients. Conclusion DC-SIGN and DC-SIGNR are blood-based molecular markers that can potentially be used for the diagnosis of early stage patients. Moreover, expression of DC-SIGN in serum and cancer tissues may affect the survival time for colon cancer patients. PMID:25504222
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2010-02-08
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NASA Astrophysics Data System (ADS)
Mukhopadhyay, Debraj; Das, Subhrajit; Arunkumar, G.; Elangovan, D.; Ragunath, G.
2017-11-01
In this paper a current fed interleaved DC - DC boost converter which has an isolated topology and used for high voltage step up is proposed. A basic DC to DC boost converter converts uncontrolled DC voltage into controlled DC voltage of higher magnitude. Whereas this topology has the advantages of lower input current ripple, lesser output voltage, lesser stress on switches, faster transient response, improved reliability and much lesser electromagnetic emission over the conventional DC to DC boost converter. Most important benefit of this interleaved DC to DC boost converter is much higher efficiency. The input current is divided into two paths, substantially ohmic loss (I2R) and inductor ac loss gets reduced and finally the system achieves much higher efficiency. With recent mandates on energy saving interleaved DC to DC boost converter may be used as a very powerful tool to maintain good power density keeping the input current manageable. Higher efficiency also allows higher switching frequency and as a result the topology becomes more compact and cost friendly. The proposed topology boosts 48v DC to 200 V DC. Switching frequency is 100 kHz and PSIM 9.1 Platform has been used for the simulation.
Ferioli, Federico; Giambanelli, Elisa; D'Antuono, L Filippo
2017-12-01
Wild fennel (Foeniculum vulgare Mill. subsp. piperitum) florets are used as a typical spice in central and southern Italy. Although fennel (Foeniculum vulgare Mill.), belonging to the Apiaceae (syn. Umbelliferae) family, is a well-known vegetable and aromatic plant, whose main phytochemical compounds have been extensively analysed and investigated as flavouring agents and for their putative health promoting functions, its florets have not been specifically considered up to now. Therefore, the volatile and phenolic composition of florets from an Italian wild fennel crop was determined at different developmental stages, and compared to that of leaves and fruits. Moreover, florets of nine Italian wild fennel populations of different geographical origin from northern-central Italy were also analysed. The total phenolic amount increased from leaves to florets, reaching its highest value in early florets, at 58 012 mg kg -1 of dry matter (DM), then constantly decreased in fruits. In florets of wild populations, phenolics ranged from 6666 to 43 368 mg kg -1 DM. The total amount of volatile compounds was more than twice higher in florets (21 449 mg kg -1 DM) than in leaves (10 470 mg kg -1 DM), reaching its highest value in fruits (50 533 mg kg -1 DM). Estragole and trans-anethole were the main compounds of the volatile fraction. Total volatiles ranged from 24 367 to 60 468 mg kg -1 DM in florets of local populations. Significant changes in the total amount and profile of both phenolic and volatile compounds occurred during plant development. The consistent increase of estragole at later developmental stages supported the claim of different sensory properties of florets and fruits. Geographical origin significantly affected phenolic and volatile composition of wild fennel florets. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.
Pulsed-DC selfsputtering of copper
NASA Astrophysics Data System (ADS)
Wiatrowski, A.; Posadowski, W. M.; Radzimski, Z. J.
2008-03-01
At standard magnetron sputtering conditions (argon pressure ~0.5 Pa) inert gas particles are often entrapped in the formed films. Inert gas contamination can be eliminated by using the self-sustained magnetron sputtering process because it is done in the absence of the inert gas atmosphere. The self-sustained sputtering (SSS) gives also a unique condition during the transport of sputtered particles to the substrate. It is especially useful for filling high aspect ratio submicron scale structures for microelectronics. So far it has been shown that the self-sputtering process can be sustained in the DC operation mode (DC-SSS) only. The main disadvantage of DC-SSS process is instability related to possible arc formation. Usage of pulsed sputtering, similarly to reactive pulsed magnetron sputtering, could eliminate this problem. In this paper results of pulsed-DC self-sustained magnetron sputtering (pulsed DC-SSS) of copper are presented for the first time. The planar magnetron equipped with a 50 mm in diameter and 6 mm thick copper target was powered by DC-power supply modulated by power switch. The maximum target power was about 11 kW (~550W/cm2). The magnetron operation was investigated as a function of pulsing frequency (20-100 kHz) and duty factor (50-90%). The discharge extinction pressure was determined for these conditions. The plasma emission spectra (400-410nm range) and deposition rates were observed for both DC and pulsed DC sustained self-sputtering processes. The presented results illustrate that stable pulsed DC-SSS process can be obtained at pulsing frequency in the range of 60-100 kHz and duty factor of 70-90%.
DC-Compensated Current Transformer.
Ripka, Pavel; Draxler, Karel; Styblíková, Renata
2016-01-20
Instrument current transformers (CTs) measure AC currents. The DC component in the measured current can saturate the transformer and cause gross error. We use fluxgate detection and digital feedback compensation of the DC flux to suppress the overall error to 0.15%. This concept can be used not only for high-end CTs with a nanocrystalline core, but it also works for low-cost CTs with FeSi cores. The method described here allows simultaneous measurements of the DC current component.
Cryogenic Evaluation of an Advanced DC/DC Converter Module for Deep Space Applications
NASA Technical Reports Server (NTRS)
Elbuluk, Malik E.; Hammoud, Ahmad; Gerber, Scott S.; Patterson, Richard
2003-01-01
DC/DC converters are widely used in power management, conditioning, and control of space power systems. Deep space applications require electronics that withstand cryogenic temperature and meet a stringent radiation tolerance. In this work, the performance of an advanced, radiation-hardened (rad-hard) commercial DC/DC converter module was investigated at cryogenic temperatures. The converter was investigated in terms of its steady state and dynamic operations. The output voltage regulation, efficiency, terminal current ripple characteristics, and output voltage response to load changes were determined in the temperature range of 20 to -140 C. These parameters were obtained at various load levels and at different input voltages. The experimental procedures along with the results obtained on the investigated converter are presented and discussed.
NASA DC-8 airborne research laboratory
NASA Technical Reports Server (NTRS)
Degreef, Leo H.
1991-01-01
Since the summer of 1987, NASA Ames Research Center has been operating a DC-8 equipped with CFM 56 engines as a flying research laboratory. In this relatively short time, the DC-8, with its tremendous capabilities, has made significant contributions to numerous scientific fields. Capable of staying aloft for over 12 hours, the DC-8 has flown directly over both the North and South Poles, gathering data relating to the ozone hole. Operating from a few thousand feet to over 40,000 feet above sea level the interchangeable payload capability of the DC-8 has made it a versatile scientific tool. The DC-8 also plays a vital role in the development of new satellite-borne sensors as very often those sensors are test-flown on the DC-8 before they are launched into space. The tremendous range and instrument carrying capability make the DC-8 an ideal flying laboratory. A few of the programs the DC-8 has participated in as well as a sampling of the instruments carried are outlined.
Efficient Visible Light Communication Transmitters Based on Switching-Mode dc-dc Converters
2018-01-01
Visible light communication (VLC) based on solid-state lighting (SSL) is a promising option either to supplement or to substitute existing radio frequency (RF) wireless communication in indoor environments. VLC systems take advantage of the fast modulation of the visible light that light emitting diodes (LEDs) enable. The switching-mode dc-to-dc converter (SMCdc-dc) must be the cornerstone of the LED driver of VLC transmitters in order to incorporate the communication functionality into LED lighting, keeping high power efficiency. However, the new requirements related to the communication, especially the high bandwidth that the LED driver must achieve, converts the design of the SMCdc-dc into a very challenging task. In this work, three different methods for achieving such a high bandwidth with an SMCdc-dc are presented: increasing the order of the SMCdc-dc output filter, increasing the number of voltage inputs, and increasing the number of phases. These three strategies are combinable and the optimum design depends on the particular VLC application, which determines the requirements of the VLC transmitter. As an example, an experimental VLC transmitter based on a two-phase buck converter with a fourth-order output filter will demonstrate that a bandwidth of several hundred kilohertz (kHz) can be achieved with output power levels close to 10 W and power efficiencies between 85% and 90%. In conclusion, the design strategy presented allows us to incorporate VLC into SSL, achieving high bit rates without damaging the power efficiency of LED lighting. PMID:29642455
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-05
... Airplanes, DC-9-81 (MD-81) Airplanes, DC-9-82 (MD-82) Airplanes, DC-9-83 (MD-83) Airplanes, DC-9- 87 (MD-87...) airplanes, DC-9-87 (MD-87) airplanes, MD-88 airplanes, and MD-90-30 airplanes. That AD currently requires... INFORMATION: Discussion On June 18, 2010, we issued AD 2009-15-16, Amendment 39-16345 (75 FR 38017, July 1...
Efficiency and Regulation of Commercial Low Power DC/DC Converter Modules at Low Temperatures
NASA Technical Reports Server (NTRS)
Elbuluk, Malik E.; Gerber, Scott; Hammoud, Ahmad; Patterson, Richard L.
2000-01-01
DC/DC converters that are capable of operating at cryogenic temperatures are anticipated to play an important role in the power systems of future NASA deep space missions. Design of these converters to survive cryogenic temperatures will improve the power system performance, and reduce development and launch costs. At the NASA Glenn Research Center Low Temperature Electronics Laboratory, several commercial off-the-shelf dc/dc converter modules were evaluated for their low temperature performance. Various parameters were investigated as a function of temperature, in the range of 20 C to -190 C. Data pertaining to the efficiency and voltage regulation of the tested converters is presented and discussed.
Jiang, Bo; Grage-Griebenow, Evelin; Csernok, Elena; Butherus, Kristine; Ehlers, Stefan; Gross, Wolfgang L; Holle, Julia U
2010-01-01
The aim of the study was to assess PAR-2 expression on dendritic cell (DC) subsets and other immune cells of Wegener's granulomatosis (WG) patients and healthy controls (HC) and to investigate whether Proteinase 3 (PR3, a serine protease which can activate PAR2) induces maturation of human DC-like monocytes and murine Flt-3 ligand- and GM-CSF-generated DC. Human peripheral blood cells including DC subsets and Flt-3l- and GM-CSF-generated mouse DC were analysed for expression of PAR-2 and DC maturation markers by flow cytometry before and after stimulation with PR3, trypsin, PAR-2 agonist or LPS for 24 h. There was no difference of PAR-2 expression on PMNs, monocytes, lymphocytes and DC between all WG samples and HC. However, in inactive WG, expression of PAR-2 was downregulated on the cell surface of PMNs, monocytes, lymphocytes, and CD11c+DC compared to active WG and HC. PR3 and PAR2-agonists did not induce upregulation of PAR-2 or maturation markers of human DC-like monocytes in WG and HC. Likewise, murine PR3 did not induce upregulation of PAR-2 or maturation markers in murine DC. PAR-2 expression is downregulated on human peripheral blood cells including CD11c+ DC in inactive WG compared to active WG and HC, possibly reflecting a non-activated status of these cells in inactive disease. PR3 and PAR-2- agonists did not induce maturation of human ex vivo DC-like monocytes in WG and HC and of murine DC, suggesting this pathway is not singularly involved in the maturation of these cell subsets.
Frenz, Theresa; Graalmann, Lukas; Detje, Claudia N; Döring, Marius; Grabski, Elena; Scheu, Stefanie; Kalinke, Ulrich
2014-09-01
Upon treatment with vesicular stomatitis virus (VSV) particles, plasmacytoid dendritic cells (pDC) are triggered to mount substantial type I IFN responses, whereas myeloid DC (mDC) are only minor producers. Interestingly, bone marrow-derived (BM-)mDC were more vulnerable to infection with enhanced GFP (eGFP)-expressing VSV (VSVeGFP) than BM-pDC. BM-pDC stimulated with wild-type VSV mounted TLR-dependent IFN responses that were independent of RIG-I-like helicase (RLH) signaling. In contrast, in BM-pDC the VSV variant M2 induced particularly high IFN responses triggered in a TLR- and RLH-dependent manner, whereas BM-mDC stimulation was solely RLH-dependent. Importantly, VSVeGFP treatment of BM-pDC derived from IFN-β yellow fluorescent protein (YFP) reporter mice (messenger of IFN-β) resulted in YFP(+) and eGFP(+) single-positive cells, whereas among messenger of IFN-β-BM-mDC most YFP(+) cells were also eGFP(+). This observation indicated that unlike mDC, direct virus infection was not required to trigger IFN responses of pDC. VSV-infected BM-mDC triggered BM-pDC to mount significantly higher IFN responses than free virus particles. Stimulation with infected cells enhanced the percentages of pDC subsets expressing either IFN-β(+) or IFN-α6(+) plus IFN-β(+). Irrespective of whether stimulated with free virus or infected cells, IFN induction was dependent on autophagy of pDC, whereas autophagy of the infected mDC was dispensable. Collectively, these results indicated that productive VSV infection was needed to trigger IFN responses of mDC, but not of pDC, and that IFN responses were primarily induced by virus-infected cells that stimulated pDC in a TLR-dependent manner. Copyright © 2014 by The American Association of Immunologists, Inc.
NASA Technical Reports Server (NTRS)
Dias, W. C.
1994-01-01
RISK D/C is a prototype program which attempts to do program risk modeling for the Space Exploration Initiative (SEI) architectures proposed in the Synthesis Group Report. Risk assessment is made with respect to risk events, their probabilities, and the severities of potential results. The program allows risk mitigation strategies to be proposed for an exploration program architecture and to be ranked with respect to their effectiveness. RISK D/C allows for the fact that risk assessment in early planning phases is subjective. Although specific to the SEI in its present form, RISK D/C can be used as a framework for developing a risk assessment program for other specific uses. RISK D/C is organized into files, or stacks, of information, including the architecture, the hazard, and the risk event stacks. Although predefined, all stacks can be upgraded by a user. The architecture stack contains information concerning the general program alternatives, which are subsequently broken down into waypoints, missions, and mission phases. The hazard stack includes any background condition which could result in a risk event. A risk event is anything unfavorable that could happen during the course of a specific point within an architecture, and the risk event stack provides the probabilities, consequences, severities, and any mitigation strategies which could be used to reduce the risk of the event, and how much the risk is reduced. RISK D/C was developed for Macintosh series computers. It requires HyperCard 2.0 or later, as well as 2Mb of RAM and System 6.0.8 or later. A Macintosh II series computer is recommended due to speed concerns. The standard distribution medium for this package is one 3.5 inch 800K Macintosh format diskette. RISK D/C was developed in 1991 and is a copyrighted work with all copyright vested in NASA. Macintosh and HyperCard are trademarks of Apple Computer, Inc.
Research of digital controlled DC/DC converter based on STC12C5410AD
NASA Astrophysics Data System (ADS)
Chen, Dan-Jiang; Jin, Xin; Xiao, Zhi-Hong
2010-02-01
In order to study application of digital control technology on DC/DC converter, principle of increment mode PID control algorithm was analyzed in the paper. Then, a SCM named STC12C5410AD was introduced with its internal resources and characteristics. The PID control algorithm can be implemented easily based on it. The output of PID control was used to change the value of a variable that is 255 times than duty cycle, and this reduced the error of calculation. The valid of the presented algorithm was verified by an experiment for a BUCK DC/DC converter. The experimental results indicated that output voltage of the BUCK converter is stable with low ripple.
DC to DC Converter Testing for Space Applications: Use of EMI Filters and Thermal Range of Operation
NASA Technical Reports Server (NTRS)
Leon, Rosa
2008-01-01
Several tests were performed on Interpoint and International Rectifier (IR) direct current (DC) to DC converters to evaluate potential performance and reliability issues in space use of DC to DC converters and to determine if the use of electromagnetic interference (EMI) filters mitigates concerns observed during previous tests. Test findings reported here include those done up until September - October 2008. Tests performed include efficiency, regulation, cross-regulation, power consumption with inhibit on, load transient response, synchronization, and turn-on tests. Some of the test results presented here span the thermal range -55 C to 125 C. Lower range was extended to -120 C in some tested converters. Determination of failure root cause in DC/DC converters that failed at thermal extremes is also included.
Analytic derivation and evaluation of a state-trajectory control law for dc-to-dc converters
NASA Technical Reports Server (NTRS)
Burns, W. W., III; Wilson, T. G.
1977-01-01
Mathematical representations of a state-plane switching boundary employed in a state-trajectory control law for dc-to-dc converters are derived. Several levels of approximation to the switching boundary equations are presented, together with an evaluation of the effects of nonideal operating characteristics of converter power stage components on the shape and location of the boundary and the behavior of a system controlled by it. Digital computer simulations of dc-to-dc converters operating in conjunction with each of these levels of control are presented and evaluated with respect to changes in transient and steady-state performance.
Design and modelling of high gain DC-DC converters for fuel cell hybrid electric vehicles
NASA Astrophysics Data System (ADS)
Elangovan, D.; Karthigeyan, V.; Subhanu, B.; Ashwin, M.; Arunkumar, G.
2017-11-01
Transportation (Diesel and petrol internal combustion engine vehicles) approximately contributes to 25.5% of total CO2 emission. Thus diesel and petrol engine vehicles are the most dominant contributors of CO2 emission which leads global warming which causes climate change. The problem of CO2 emission and global warming can be reduced by focusing on renewable energy vehicles. Out of the available renewable energy sources fuel cell is the only source which has reasonable efficiency and can be used in vehicles. But the main disadvantage of fuel cell is its slow response time. So energy storage systems like batteries and super capacitors are used in parallel with the fuel cell. Fuel cell is used during steady state vehicle operation while during transient conditions like starting, acceleration and braking batteries and super capacitors can supply or absorb energy. In this paper a unidirectional fuel cell DC-DC converter and bidirectional energy storage system DC-DC converter is proposed, which can interface dc sources at different voltage levels to the dc bus and also it can independently control the power flow from each energy source to the dc bus and vice versa. The proposed converters are designed and simulated using PSIM version 9.1.1 and gate pulse pattern, input and output voltage waveforms of the converters for steady state operation are studied.
DC-DC Type High-Frequency Link DC for Improved Power Quality of Cascaded Multilevel Inverter
NASA Astrophysics Data System (ADS)
Sadikin, Muhammad; Senjyu, Tomonobu; Yona, Atsushi
2013-06-01
Multilevel inverters are emerging as a new breed of power converter options for power system applications. Recent advances in power switching devices enabled the suitability of multilevel inverters for high voltage and high power applications because they are connecting several devices in series without the need of component matching. Usually, a transformerless battery energy storage system, based on a cascaded multilevel inverter, is used as a measure for voltage and frequency deviations. System can be reduced in size, weight, and cost of energy storage system. High-frequency link circuit topology is advantageous in realizing compact and light-weight power converters for uninterruptible power supply systems, new energy systems using photovoltaic-cells, fuel-cells and so on. This paper presents a DC-DC type high-frequency link DC (HFLDC) cascaded multilevel inverter. Each converter cell is implemented a control strategy for two H-bridge inverters that are controlled with the same multicarrier pulse width modulation (PWM) technique. The proposed cascaded multilevel inverter generates lower voltage total harmonic distortion (THD) in comparison with conventional cascaded multilevel inverter. Digital simulations are carried out using PSCAD/EMTDC to validate the performance of the proposed cascaded multilevel inverter.
NASA Astrophysics Data System (ADS)
Huang, Peter Jen-Hung
This research first proposes a method to merge photovoltaic (PV) cells or PV panels within the internal components DC-DC converters. The purpose of this merged structure is to reconfigure the PV modules between series and parallel connections using high switching frequencies (hundreds of kHz). This leads to multi-levels of voltages and currents that become applied to the output filter of the converter. Further, this research introduces a concept of a switching cell that utilizes the reconfiguration of series and parallel connections in DC-DC converters. The switching occurs at high switching frequency and the switches can be integrated to be within the solar panels or in between the solar cells. The concept is generalized and applied to basic buck and boost topologies. As examples of the new types of converters: reconfigurable PV-buck and PV-boost converter topologies are presented. It is also possible to create other reconfigurable power converters: non-isolated and isolated topologies. Analysis, simulation and experimental verification for the reconfigurable PV-buck and PV-boost converters are presented extensively to illustrate proof of concept. Benefits and drawbacks of the new approach are discussed. The second part of this research proposes to utilize the internal solar cell capacitance and internal solar module wire parasitic inductances to replace the input capacitor and filter inductor in boost derived DC-DC converters for energy harvesting applications. High switching frequency (MHz) hard switched and resonant boost converters are proposed. Their analysis, simulation and experimental prototypes are presented. A specific proof-of-concept application is especially tested for foldable PV panels, which are known for their high internal wire inductance. The experimental converters successfully boost solar module voltage without adding any external input capacitance or filter inductor. Benefits and drawbacks of new proposed PV submodule integrated boost
Light-weight DC to very high voltage DC converter
Druce, Robert L.; Kirbie, Hugh C.; Newton, Mark A.
1998-01-01
A DC-DC converter capable of generating outputs of 100 KV without a transformer comprises a silicon opening switch (SOS) diode connected to allow a charging current from a capacitor to flow into an inductor. When a specified amount of charge has flowed through the SOS diode, it opens up abruptly; and the consequential collapsing field of the inductor causes a voltage and current reversal that is steered into a load capacitor by an output diode. A switch across the series combination of the capacitor, inductor, and SOS diode closes to periodically reset the SOS diode by inducing a forward-biased current.
The 25 kW resonant dc/dc power converter
NASA Technical Reports Server (NTRS)
Robson, R. R.
1983-01-01
The feasibility of processing 25-kW of power with a single, transistorized, series resonant converter stage was demonstrated by the successful design, development, fabrication, and testing of such a device which employs four Westinghouse D7ST transistors in a full-bridge configuration and operates from a 250-to-350 Vdc input bus. The unit has an overall worst-case efficiency of 93.5% at its full rated output of 1000 V and 25 A dc. A solid-state dc input circuit breaker and output-transient-current limiters are included in and integrated into the design. Full circuit details of the converter are presented along with the test data.
Light-weight DC to very high voltage DC converter
Druce, R.L.; Kirbie, H.C.; Newton, M.A.
1998-06-30
A DC-DC converter capable of generating outputs of 100 KV without a transformer comprises a silicon opening switch (SOS) diode connected to allow a charging current from a capacitor to flow into an inductor. When a specified amount of charge has flowed through the SOS diode, it opens up abruptly; and the consequential collapsing field of the inductor causes a voltage and current reversal that is steered into a load capacitor by an output diode. A switch across the series combination of the capacitor, inductor, and SOS diode closes to periodically reset the SOS diode by inducing a forward-biased current. 1 fig.
NASA Astrophysics Data System (ADS)
Elangovan, D.; Archana, R.; Jayadeep, V. J.; Nithin, M.; Arunkumar, G.
2017-11-01
More than fifty percent Indian population do not have access to electricity in daily lives. The distance between the power generating stations and the distribution centers forms one of the main reasons for lack of electrification in rural and remote areas. Here lies the importance of decentralization of power generation through renewable energy resources. In the present world, electricity is predominantly powered by alternating current, but most day to day devices like LED lamps, computers and electrical vehicles, all run on DC power. By directly supplying DC to these loads, the number of power conversion stages was reduced, and overall system efficiency increases. Replacing existing AC network with DC is a humongous task, but with power electronic techniques, this project intends to implement DC grid at a household level in remote and rural areas. Proposed work was designed and simulated successfully for various loads amounting to 250 W through appropriate power electronic convertors. Maximum utilization of the renewable sources for domestic and commercial application was achieved with the proposed DC topology.
Static and Dynamic Characteristics of DC-DC Converter Using a Digital Filter
NASA Astrophysics Data System (ADS)
Kurokawa, Fujio; Okamatsu, Masashi
This paper presents the regulation and dynamic characteristics of the dc-dc converter with digital PID control, the minimum phase FIR filter or the IIR filter, and then the design criterion to improve the dynamic characteristics is discussed. As a result, it is clarified that the DC-DC converter using the IIR filter method has superior performance characteristics. The regulation range is within 1.3%, the undershoot against the step change of the load is less than 2% and the transient time is less than 0.4ms with the IIR filter method. In this case, the switching frequency is 100kHz and the step change of the load R is from 50 Ω to 10 Ω. Further, the superior characteristics are obtained when the first gain, the second gain and the second cut-off frequency are relatively large, and the first cut-off frequency and the passing frequency are relatively low. Moreover, it is important that the gain strongly decreases at the second cut-off frequency because the upper band pass frequency range must be always less than half of the sampling frequency based on the sampling theory.
DC-Compensated Current Transformer †
Ripka, Pavel; Draxler, Karel; Styblíková, Renata
2016-01-01
Instrument current transformers (CTs) measure AC currents. The DC component in the measured current can saturate the transformer and cause gross error. We use fluxgate detection and digital feedback compensation of the DC flux to suppress the overall error to 0.15%. This concept can be used not only for high-end CTs with a nanocrystalline core, but it also works for low-cost CTs with FeSi cores. The method described here allows simultaneous measurements of the DC current component. PMID:26805830
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ERIC Educational Resources Information Center
Zumel, P.; Fernandez, C.; Sanz, M.; Lazaro, A.; Barrado, A.
2011-01-01
In this paper, a short introductory course to introduce field-programmable gate array (FPGA)-based digital control of dc/dc switching power converters is presented. Digital control based on specific hardware has been at the leading edge of low-medium power dc/dc switching converters in recent years. Besides industry's interest in this topic, from…
Informational model verification of ZVS Buck quasi-resonant DC-DC converter
NASA Astrophysics Data System (ADS)
Vakovsky, Dimiter; Hinov, Nikolay
2016-12-01
The aim of the paper is to create a polymorphic informational model of a ZVS Buck quasi-resonant DC-DC converter for the modeling purposes of the object. For the creation of the model is applied flexible open standards for setting, storing, publishing and exchange of data in distributed information environment. The created model is useful for creation of many and different by type variants with different configuration of the composing elements and different inner model of the examined object.
High-Efficiency Photovoltaic System Using Partially-Connected DC-DC Converter
NASA Astrophysics Data System (ADS)
Uno, Masatoshi; Kukita, Akio; Tanaka, Koji
Power conversion electronics for photovoltaic (PV) systems are desired to operate as efficiently as possible to exploit the power generated by PV modules. This paper proposes a novel PV system in which a dc-dc converter is partially connected to series-connected PV modules. The proposed system achieves high power-conversion efficiency by reducing the passing power and input/output voltages of the converter. The theoretical operating principle was experimentally validated. Resultant efficiency performances of the proposed and conventional systems demonstrated that the proposed system was more efficient in terms of power conversion though the identical converter was used for the both systems.
Regulation of a lightweight high efficiency capacitator diode voltage multiplier dc-dc converter
NASA Technical Reports Server (NTRS)
Harrigill, W. T., Jr.; Myers, I. T.
1976-01-01
A method for the regulation of a capacitor diode voltage multiplier dc-dc converter has been developed which has only minor penalties in weight and efficiency. An auxiliary inductor is used, which only handles a fraction of the total power, to control the output voltage through a pulse width modulation method in a buck boost circuit.
Research and Construction of DC Energy Measurement Traceability Technology
NASA Astrophysics Data System (ADS)
Zhi, Wang; Maotao, Yang; Jing, Yang
2018-02-01
With the implementation of energy saving and emission reduction policies, DC energy metering has been widely used in many fields. In view of the lack of a DC energy measurementtraceability system, in combination with the process of downward measurement transfer in relation to the DC charger-based field calibration technology and DC energy meter and shunt calibration technologies, the paper proposed DC fast charging, high DC, small DC voltage output and measuring technologies, and built a time-based plan by converting high DC voltage into low voltage and high current into low current and then into low voltage, leaving DC energy traceable to national standards in terms of voltage, current and time and thus filling in the gap in DC energy measurement traceability.
Gigley, Jason P; Khan, Imtiaz A
2011-01-01
Age associated impairment of immune function results in inefficient vaccination, tumor surveillance and increased severity of infections. Several alterations in adaptive immunity have been observed and recent studies report age related declines in innate immune responses to opportunistic pathogens including Encephalitozoon cuniculi. We previously demonstrated that conventional dendritic cells (cDC) from 9-month-old animals exhibit sub-optimal response to E. cuniculi infection, suggesting that age associated immune senescence begins earlier than expected. We focused this study on how age affects plasmacytoid DC (pDC) function. More specifically how aged pDC affect cDC function as we observed that the latter are the predominant activators of CD8 T cells during this infection. Our present study demonstrates that pDC from middle-aged mice (12 months) suppress young (8 week old) cDC driven CD8 T cell priming against E. cuniculi infection. The suppressive effect of pDC from older mice decreased maturation of young cDC via cell contact. Aged mouse pDC exhibited higher expression of PD-L1 and blockade of their interaction with cDC via this molecule restored cDC maturation and T cell priming. Furthermore, the PD-L1 dependent suppression of cDC T cell priming was restricted to effector function of antigen-specific CD8 T cells not their expansion. To the best of our knowledge, the data presented here is the first report highlighting a cell contact dependent, PD-L1 regulated, age associated defect in a DC subpopulation that results in a sub-optimal immune response against E. cuniculi infection. These results have broad implications for design of immunotherapeutic approaches to enhance immunity for aging populations.
An Integrated Programmable Wide-range PLL for Switching Synchronization in Isolated DC-DC Converters
NASA Astrophysics Data System (ADS)
Fard, Miad
In this thesis, two Phase-Locked-Loop (PLL) based synchronization schemes are introduced and applied to a bi-directional Dual-Active-Bridge (DAB) dc-dc converter with an input voltage up to 80 V switching in the range of 250 kHz to 1 MHz. The two schemes synchronize gating signals across an isolated boundary without the need for an isolator per transistor. The Power Transformer Sensing (PTS) method utilizes the DAB power transformer to indirectly sense switching on the secondary side of the boundary, while the Digital Isolator Sensing (DIS) method utilizes a miniature transformer for synchronization and communication at up to 100 MHz. The PLL is implemented on-chip, and is used to control an external DAB power-stage. This work will lead to lower cost, high-frequency isolated dc-dc converters needed for a wide variety of emerging low power applications where isolator cost is relatively high and there is a demand for the reduction of parts.
NASA Astrophysics Data System (ADS)
Jayaweera, H. M. P. C.; Muhtaroğlu, Ali
2016-11-01
A novel model based methodology is presented to determine optimal device parameters for the fully integrated ultra low voltage DC-DC converter for energy harvesting applications. The proposed model feasibly contributes to determine the maximum efficient number of charge pump stages to fulfill the voltage requirement of the energy harvester application. The proposed DC-DC converter based power consumption model enables the analytical derivation of the charge pump efficiency when utilized simultaneously with the known LC tank oscillator behavior under resonant conditions, and voltage step up characteristics of the cross-coupled charge pump topology. The verification of the model has been done using a circuit simulator. The optimized system through the established model achieves more than 40% maximum efficiency yielding 0.45 V output with single stage, 0.75 V output with two stages, and 0.9 V with three stages for 2.5 kΩ, 3.5 kΩ and 5 kΩ loads respectively using 0.2 V input.
State trajectories used to observe and control dc-to-dc converters
NASA Technical Reports Server (NTRS)
Burns, W. W., III; Wilson, T. G.
1976-01-01
State-plane analysis techniques are employed to study the voltage stepup energy-storage dc-to-dc converter. Within this framework, an example converter operating under the influence of a constant on-time and a constant frequency controller is examined. Qualitative insight gained through this approach is used to develop a conceptual free-running control law for the voltage stepup converter which can achieve steady-state operation in one on/off cycle of control. Digital computer simulation data are presented to illustrate and verify the theoretical discussions presented.
Design of an Input-Parallel Output-Parallel LLC Resonant DC-DC Converter System for DC Microgrids
NASA Astrophysics Data System (ADS)
Juan, Y. L.; Chen, T. R.; Chang, H. M.; Wei, S. E.
2017-11-01
Compared with the centralized power system, the distributed modularized power system is composed of several power modules with lower power capacity to provide a totally enough power capacity for the load demand. Therefore, the current stress of the power components in each module can then be reduced, and the flexibility of system setup is also enhanced. However, the parallel-connected power modules in the conventional system are usually controlled to equally share the power flow which would result in lower efficiency in low loading condition. In this study, a modular power conversion system for DC micro grid is developed with 48 V dc low voltage input and 380 V dc high voltage output. However, in the developed system control strategy, the numbers of power modules enabled to share the power flow is decided according to the output power at lower load demand. Finally, three 350 W power modules are constructed and parallel-connected to setup a modular power conversion system. From the experimental results, compared with the conventional system, the efficiency of the developed power system in the light loading condition is greatly improved. The modularized design of the power system can also decrease the power loss ratio to the system capacity.
Design and implementation of current fed DC-DC converter for PHEV application using renewable source
NASA Astrophysics Data System (ADS)
Milind Metha, Manish; Tutki, Sanjay; Rajan, Aju; Elangovan, D.; Arunkumar, G.
2017-11-01
As the fossil fuels are depleting day by day, the use of renewable energy sources came into existence and they evolved a lot lately. To increase efficiency and productivity in the hybrid vehicles, the existence less efficient petroleum and diesel IC engines need to be replaced with the new and efficient converters with renewable energy sources. This has to be done in such a way that impacts three factors mainly: cost, efficiency and reliability. The PHEVs that have been launched and the upcoming PHEVs using converters with voltage range around 380V to 400V generated with power ranges between 2.4KW to 2.8KW. The basic motto of this paper is to design a prolific converter while considering the factor such as cost and size. In this paper, a two stage DC-DC converter is proposed and the proposed DC-DC converter is utilized to endeavour voltage from 24V (photovoltaic source) to a yield voltage of 400V and to meet the power demand of 250W, since only one panel is being used for this proposed paper. This paper discuss in detail about why and how the current fed DC-DC converter is utilized along with a voltage doubler, thus reducing transformer turns and thereby reducing overall size of the product. Simulation and hardware results have been presented along with calculations for duty cycle required for firing sequence for different values of transformer turns.
Gigley, Jason P.; Khan, Imtiaz A.
2011-01-01
Age associated impairment of immune function results in inefficient vaccination, tumor surveillance and increased severity of infections. Several alterations in adaptive immunity have been observed and recent studies report age related declines in innate immune responses to opportunistic pathogens including Encephalitozoon cuniculi. We previously demonstrated that conventional dendritic cells (cDC) from 9-month-old animals exhibit sub-optimal response to E. cuniculi infection, suggesting that age associated immune senescence begins earlier than expected. We focused this study on how age affects plasmacytoid DC (pDC) function. More specifically how aged pDC affect cDC function as we observed that the latter are the predominant activators of CD8 T cells during this infection. Our present study demonstrates that pDC from middle-aged mice (12 months) suppress young (8 week old) cDC driven CD8 T cell priming against E. cuniculi infection. The suppressive effect of pDC from older mice decreased maturation of young cDC via cell contact. Aged mouse pDC exhibited higher expression of PD-L1 and blockade of their interaction with cDC via this molecule restored cDC maturation and T cell priming. Furthermore, the PD-L1 dependent suppression of cDC T cell priming was restricted to effector function of antigen-specific CD8 T cells not their expansion. To the best of our knowledge, the data presented here is the first report highlighting a cell contact dependent, PD-L1 regulated, age associated defect in a DC subpopulation that results in a sub-optimal immune response against E. cuniculi infection. These results have broad implications for design of immunotherapeutic approaches to enhance immunity for aging populations. PMID:21695169
Foundations of DC plasma sources
NASA Astrophysics Data System (ADS)
Tomas Gudmundsson, Jon; Hecimovic, Ante
2017-12-01
A typical dc discharge is configured with the negative cathode at one end and a positive anode at the other end, separated by a gas filled gap, placed inside a long glass cylinder. A few hundred volts between the cathode and anode is required to maintain the discharge. The type of discharge that is formed between the two electrodes depends upon the pressure of the working gas, the nature of the working gas, the applied voltage and the geometry of the discharge. We discuss the current-voltage characteristics of the discharge as well as the distinct structure that develops in the glow discharge region. The dc glow discharge appears in the discharge current range from μA to mA at 0.5-300 Pa pressure. We discuss the various phenomena observed in the dc glow discharge, including the cathode region, the positive column, and striations. The dc glow discharge is maintained by the emission of secondary electrons from the cathode target due to the bombardment of ions. For decades, the dc glow discharge has been used as a sputter source. Then it is often operated as an obstructed abnormal glow discharge and the required applied voltage is in the range 2-5 kV. Typically, the cathode target (the material to be deposited) is connected to a negative voltage supply (dc or rf) and the substrate holder faces the target. The relatively high operating pressure, in the range from 2 to 4 Pa, high applied voltages, and the necessity to have a conductive target limit the application of dc glow discharge as a sputter source. In order to lower the discharge voltage and expand the operation pressure range, the lifetime of the electrons in target vicinity is increased through applying magnetic field, by adding permanent magnets behind the cathode target. This arrangement is coined the magnetron sputtering discharge. The various configurations of the magnetron sputtering discharge and its applications are described. Furthermore, the use of dc discharges for chemical analysis, the Penning
Some results regarding stability of photovoltaic maximum-power-point tracking dc-dc converters
NASA Astrophysics Data System (ADS)
Schaefer, John F.
An analytical investigation of a class of photovoltaic (PV) maximum-power-point tracking dc-dc converters has yielded basic results relative to the stability of such devices. Necessary and sufficient conditions for stable operation are derived, and design tools are given. Specific results have been obtained for arbitrary PV arrays driving converters powering resistive loads and batteries. The analytical techniques are applicable to inverters, also. Portions of the theoretical results have been verified in operational devices: a 1500 watt unit has driven a 1-horsepower, 90-volt dc motor powering a water pump jack for over one year. Prior to modification shortly after initial installation, the unit exhibited instability at low levels of irradiance, as predicted by the theory. Two examples are provided.
DC-based magnetic field controller
Kotter, Dale K.; Rankin, Richard A.; Morgan, John P,.
1994-01-01
A magnetic field controller for laboratory devices and in particular to dc operated magnetic field controllers for mass spectrometers, comprising a dc power supply in combination with improvements to a hall probe subsystem, display subsystem, preamplifier, field control subsystem, and an output stage.
NASA Astrophysics Data System (ADS)
Calderone, Luigi; Pinola, Licia; Varoli, Vincenzo
1992-04-01
The paper describes an analytical procedure to optimize the feed-forward compensation for any PWM dc/dc converters. The aims of achieving zero dc audiosusceptibility was found to be possible for the buck, buck-boost, Cuk, and SEPIC cells; for the boost converter, however, only nonoptimal compensation is feasible. Rules for the design of PWM controllers and procedures for the evaluation of the hardware-introduced errors are discussed. A PWM controller implementing the optimal feed-forward compensation for buck-boost, Cuk, and SEPIC cells is described and fully experimentally characterized.
Multiphase High-Frequency Isolated DC-DC Converter for Industrial Applications
NASA Astrophysics Data System (ADS)
Maurya, Rakesh; Srivastava, S. P.; Agarwal, Pramod
2014-01-01
Industrial applications such as welding, plasma cutting, and surface hardening require a large DC current at low voltage. In such applications, the rating of power supply varies from few kilowatts to hundreds of kilowatts. The power supply employs in such applications particularly in arc welding process is expected to operate from open-circuit (no-load) to short-circuit (when the electrode sticks to the workpiece for a short span of time) quickly. In this paper, high-frequency isolated multiphase DC-DC converter is proposed which is well suited for aforementioned applications. Based on mathematical analysis, a simulation study with 5 kW, 5 V/1,000 A proposed model is carried out using Simulink block set and Sim Power System tool box and its performances are evaluated under symmetrical control methods. To verify the simulation results, scaled prototype model of rating 1.5 V/100 A is developed and tested with aforementioned control method under different operating conditions. In comparison with conventional welding power supply employed in many industries, the performance of proposed converter is improved significantly in terms of size and weight, efficiency and dynamic response.
CMOS-Compatible SOI MESFETS for Radiation-Hardened DC-to-DC Converters
NASA Technical Reports Server (NTRS)
Thornton, Trevor; Lepkowski, William; Wilk, Seth
2013-01-01
A radiation-tolerant transistor switch has been developed that can operate between 196 and +150 C for DC-to-DC power conversion applications. A prototype buck regulator component was demonstrated to be performing well after a total ionizing dose of 300 krad(Si). The prototype buck converters showed good efficiencies at ultra-high switching speeds in the range of 1 to 10 MHz. Such high switching frequency will enable smaller, lighter buck converters to be developed as part of the next project. Switching regulators are widely used in commercial applications including portable consumer electronics.
Low-temperature operation of a Buck DC/DC converter
NASA Technical Reports Server (NTRS)
Ray, Biswajit; Gerber, Scott S.; Patterson, Richard L.; Myers, Ira T.
1995-01-01
Low-temperature (77 K) operation of a 42/28 V, 175 W, 50 kHz PWM Buck DC/DC converter designed with commercially available components is reported. Overall, the converter losses decreased at 77 K compared to room temperature operation. A full-load efficiency of 97 percent was recorded at liquid-nitrogen temperature, compared to 95.8 percent at room temperature. Power MOSFET operation improved significantly where as the output rectifier operation deteriorated at low-temperature. The performance of the output filter inductor and capacitor did not change significantly at 77 K compared to room temperature performance. It is possible to achieve high-density and high efficiency power conversion at low-temperatures due to improved electronic, electrical and thermal properties of materials.
Tine, Yoro; Renucci, Franck; Costa, Jean; Wélé, Alassane; Paolini, Julien
2017-01-22
The metabolites from the coumarin class, present in tissues of plants belonging mainly to the Rutaceae and Apiaceae families, included compounds with high chemical diversity such as simple coumarins and furocoumarins. These health-promoting components are recognized for their valuable biological activities in herbal preparations but also for their phototoxic effects. In this work, a targeted liquid chromatography (LC) coupled with tandem mass spectrometry (MS²) was developed for the screening of 39 reference standards of coumarins and furocoumarins in essential oils and plant extracts. Chromatographic separation was accomplished on reversed phase column using water/acetonitrile as the mobile phase and detection was performed on a hybrid QqQ/linear ion trap spectrometer fitted with an atmospheric pressure chemical ionization (APCI) source operating in positive ion mode. This analytical approach was applied to investigate the coumarin compositions of fruit essential oils and methanolic extracts obtained from separated parts (fruit, leaf, stem, trunk, and root) of Zanthoxylum zanthoxyloides . Ten coumarins and six furanocoumarins were reported in this species and data analyses were used to assess the suitability of these compounds to the metabolomics-based differentiation of plant organs. The quantification criteria of the metabolites in extract samples included linearity, limit of quantification, limit of detection, and matrix effect were validated. As reported for other species of the Rutaceae family, the concentration of coumarins was drastically higher in Z. zanthoxyloides fruits than in other plant organs.
Efficiency and weight of voltage multiplier type ultra lightweight dc-dc converters
NASA Technical Reports Server (NTRS)
Harrigill, W. T., Jr.; Myers, I. T.
1975-01-01
An analytical and experimental study was made of a capacitor-diode voltage multiplier without a transformer which offers the possibility of high efficiency with light weight. The dc-dc conversion efficiencies of about 94 percent were achieved at output powers of 150 watts at 1000 volts using 8x multiplication. A detailed identification of losses was made, including forward drop losses in component, switching losses, reverse junction capacitance charging losses, and charging losses in the main ladder capacitors.
SEE Transient Response of Crane Interpoint Single Output Point of Load DC-DC Converters
NASA Technical Reports Server (NTRS)
Sanders, Anthony B.; Chen, Dakai; Kim, Hak S.; Phan, Anthony M.
2011-01-01
This study was undertaken to determine the single event effect and transient susceptibility of the Crane Interpoint Maximum Flexible Power (MFP) Single Output Point of Load DC/DC Converters for transient interruptions in the output signal and for destructive and non destructive events induced by exposing it to a heavy ion beam..
Hargrove, Douglas L.
2004-09-14
A portable, hand-held meter used to measure direct current (DC) attenuation in low impedance electrical signal cables and signal attenuators. A DC voltage is applied to the signal input of the cable and feedback to the control circuit through the signal cable and attenuators. The control circuit adjusts the applied voltage to the cable until the feedback voltage equals the reference voltage. The "units" of applied voltage required at the cable input is the system attenuation value of the cable and attenuators, which makes this meter unique. The meter may be used to calibrate data signal cables, attenuators, and cable-attenuator assemblies.
Halbach array DC motor/generator
Merritt, B.T.; Dreifuerst, G.R.; Post, R.F.
1998-01-06
A new configuration of DC motor/generator is based on a Halbach array of permanent magnets. This motor does not use ferrous materials so that the only losses are winding losses and losses due to bearings and windage. An ``inside-out`` design is used as compared to a conventional motor/generator design. The rotating portion, i.e., the rotor, is on the outside of the machine. The stationary portion, i.e., the stator, is formed by the inside of the machine. The rotor contains an array of permanent magnets that provide a uniform field. The windings of the motor are placed in or on the stator. The stator windings are then ``switched`` or ``commutated`` to provide a DC motor/generator much the same as in a conventional DC motor. The commutation can be performed by mechanical means using brushes or by electronic means using switching circuits. The invention is useful in electric vehicles and adjustable speed DC drives. 17 figs.
Halbach array DC motor/generator
Merritt, Bernard T.; Dreifuerst, Gary R.; Post, Richard F.
1998-01-01
A new configuration of DC motor/generator is based on a Halbach array of permanent magnets. This motor does not use ferrous materials so that the only losses are winding losses and losses due to bearings and windage. An "inside-out" design is used as compared to a conventional motor/generator design. The rotating portion, i.e., the rotor, is on the outside of the machine. The stationary portion, i.e., the stator, is formed by the inside of the machine. The rotor contains an array of permanent magnets that provide a uniform field. The windings of the motor are placed in or on the stator. The stator windings are then "switched" or "commutated" to provide a DC motor/generator much the same as in a conventional DC motor. The commutation can be performed by mechanical means using brushes or by electronic means using switching circuits. The invention is useful in electric vehicles and adjustable speed DC drives.
Bifurcation Analysis of a DC-DC Bidirectional Power Converter Operating with Constant Power Loads
NASA Astrophysics Data System (ADS)
Cristiano, Rony; Pagano, Daniel J.; Benadero, Luis; Ponce, Enrique
Direct current (DC) microgrids (MGs) are an emergent option to satisfy new demands for power quality and integration of renewable resources in electrical distribution systems. This work addresses the large-signal stability analysis of a DC-DC bidirectional converter (DBC) connected to a storage device in an islanding MG. This converter is responsible for controlling the balance of power (load demand and generation) under constant power loads (CPLs). In order to control the DC bus voltage through a DBC, we propose a robust sliding mode control (SMC) based on a washout filter. Dynamical systems techniques are exploited to assess the quality of this switching control strategy. In this sense, a bifurcation analysis is performed to study the nonlinear stability of a reduced model of this system. The appearance of different bifurcations when load parameters and control gains are changed is studied in detail. In the specific case of Teixeira Singularity (TS) bifurcation, some experimental results are provided, confirming the mathematical predictions. Both a deeper insight in the dynamic behavior of the controlled system and valuable design criteria are obtained.
DC Voltage Interface Standards for Naval Applications
2015-06-24
norbert.doerry@navy.mil Dr. John Amy Naval Sea Systems Command United States Navy Washington DC , USA john.amy@navy.mil Abstract—. MIL-STD-1399...standards have been established for DC interfaces on U.S. naval surface ships. This paper provides recommendations for specific standard DC
State-plane analysis of zero-voltage-switching resonant dc/dc power converters
NASA Astrophysics Data System (ADS)
Kazimierczuk, Marian K.; Morse, William D.
The state-plane analysis technique for the zero-voltage-switching resonant dc/dc power converter family of topologies, namely the buck, boost, buck-boost, and Cuk converters is established. The state plane provides a compression of information that allows the designer to uniquely examine the nonlinear dynamics of resonant converter operation. Utilizing the state plane, resonant converter modes of operation are examined and the switching frequencies are derived for the boundaries between these modes, including the boundary of energy conversion.
NASA Technical Reports Server (NTRS)
Burns, W. W., III
1977-01-01
An analytically derived approach to the control of energy-storage dc-to-dc converters, which enables improved system performance and an extensive understanding of the manner in which this improved performance is accomplished, is presented. The control approach is derived from a state-plane analysis of dc-to-dc converter power stages which enables a graphical visualization of the movement of the system state during both steady state and transient operation. This graphical representation of the behavior of dc-to-dc converter systems yields considerable qualitative insight into the cause and effect relationships which exist between various commonly used converter control functions and the system performance which results from them.
Barua, Chandana Choudhury; Haloi, Prakash; Saikia, Beenita; Sulakhiya, Kunjbihari; Pathak, Debesh Chandra; Tamuli, Shantanu; Rizavi, Hooriah; Ren, Xinguo
2018-12-01
Depression is an inflammatory, commonly occurring and lethal psychiatric disorder having high lifetime prevalence. Zanthoxylum alatum Roxb. (Rutaceae), commonly called Timur, has high medicinal value and is used ethnomedicinally for the treatment of various diseases. To evaluate the effect of hexane extract of Z. alatum seeds (ZAHE) on lipopolysaccharide (LPS)-induced depression-like behaviour in Swiss albino mice. Mice were treated with ZAHE (100 and 200 mg/kg, p.o.) and imipramine (10 mg/kg injected i.p.) for 14 days. On 14th day of the treatment, depression-like behaviour was induced by LPS (0.83 mg/kg injected i.p.) and after 24 h of LPS administration, it was assessed by measuring behavioural parameters and biochemical estimations. Behavioural tests, including the open field test, forced swimming test, tail suspension test and sucrose preference test revealed that ZAHE (100 and 200 mg/kg, p.o.) and imipramine (10 mg/kg injected i.p.) alleviated the depression symptoms of LPS-induced mice. Moreover, ZAHE treatments reversed the LPS-induced alterations in the concentrations of norepinephrine and serotonin (5-HT) and inhibited the expression of brain-derived neurotrophic factor, pro-inflammatory cytokines and oxido-nitrosative stress in the mice. Acute toxicity was calculated to be LD 50 > 2500 mg/kg. This study showed that LPS-induced depression in mice was significantly prevented by ZAHE at both the dosages. In conclusion, ZAHE exhibited an antidepressant activity by altering monoaminergic neurotransmitters in the brain combined with its anti-inflammatory potential. Thus, it could be an effective therapeutic against inflammation-induced depression and other brain disorders.
Lan, Yi; Li, Hui; Chen, Yan-yan; Zhang, Ye-wen; Liu, Na; Zhang, Qing; Wu, Qing
2014-11-01
Our previous studies had confirmed that the essential oil from Zanthoxylum bungeanum Maxim. (Z. bungeanum oil) could effectively enhance the percutaneous permeation of drug molecules as a natural transdermal penetration enhancer. The aim of the present study is to investigate and compare the skin penetration enhancement effect of Z. bungeanum oil and its main components on traditional Chinese medicine (TCM) active components. Toxicities of Z. bungeanum oil and three selected terpene compounds (terpinen-4-ol, 1,8-cineole, and limonene) in epidermal keratinocytes (HaCaT) and dermal fibroblast (CCC-ESF-1) cell lines were measured using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Five model drugs in TCM external preparations, namely osthole (OT), tetramethylpyrazine (TMP), ferulic acid (FA), puerarin (PR), and geniposide (GP), which were selected based on their lipophilicity denoted by logKo/w, were tested using in vitro permeation studies in which vertical Franz diffusion cells and rat abdominal skin were employed. The secondary structure changes of skin stratum corneum (SC) and drug thermodynamic activities were investigated to understand their mechanisms of action using Fourier transform infrared (FTIR) spectroscopy and saturation solubility studies, respectively. It was found that Z. bungeanum oil showed lower toxicities in both HaCaT cells and CCC-ESF-1 cells compared with three terpene compounds used alone. The enhancement permeation capacities by all tested agents were in the following increasing order: terpinen-4-ol≈1,8-cineole
NASA Astrophysics Data System (ADS)
Sudhakar, N.; Rajasekar, N.; Akhil, Saya; Jyotheeswara Reddy, K.
2017-11-01
The boost converter is the most desirable DC-DC power converter for renewable energy applications for its favorable continuous input current characteristics. In other hand, these DC-DC converters known as practical nonlinear systems are prone to several types of nonlinear phenomena including bifurcation, quasiperiodicity, intermittency and chaos. These undesirable effects has to be controlled for maintaining normal periodic operation of the converter and to ensure the stability. This paper presents an effective solution to control the chaos in solar fed DC-DC boost converter since the converter experiences wide range of input power variation which leads to chaotic phenomena. Controlling of chaos is significantly achieved using optimal circuit parameters obtained through Nelder-Mead Enhanced Bacterial Foraging Optimization Algorithm. The optimization renders the suitable parameters in minimum computational time. The results are compared with the traditional methods. The obtained results of the proposed system ensures the operation of the converter within the controllable region.
IFN-α regulates Blimp-1 expression via miR-23a and miR-125b in both monocytes-derived DC and pDC.
Parlato, Stefania; Bruni, Roberto; Fragapane, Paola; Salerno, Debora; Marcantonio, Cinzia; Borghi, Paola; Tataseo, Paola; Ciccaglione, Anna Rita; Presutti, Carlo; Romagnoli, Giulia; Bozzoni, Irene; Belardelli, Filippo; Gabriele, Lucia
2013-01-01
Type I interferon (IFN-I) have emerged as crucial mediators of cellular signals controlling DC differentiation and function. Human DC differentiated from monocytes in the presence of IFN-α (IFN-α DC) show a partially mature phenotype and a special capability of stimulating CD4+ T cell and cross-priming CD8+ T cells. Likewise, plasmacytoid DC (pDC) are blood DC highly specialized in the production of IFN-α in response to viruses and other danger signals, whose functional features may be shaped by IFN-I. Here, we investigated the molecular mechanisms stimulated by IFN-α in driving human monocyte-derived DC differentiation and performed parallel studies on peripheral unstimulated and IFN-α-treated pDC. A specific miRNA signature was induced in IFN-α DC and selected miRNAs, among which miR-23a and miR-125b, proved to be negatively associated with up-modulation of Blimp-1 occurring during IFN-α-driven DC differentiation. Of note, monocyte-derived IFN-α DC and in vitro IFN-α-treated pDC shared a restricted pattern of miRNAs regulating Blimp-1 expression as well as some similar phenotypic, molecular and functional hallmarks, supporting the existence of a potential relationship between these DC populations. On the whole, these data uncover a new role of Blimp-1 in human DC differentiation driven by IFN-α and identify Blimp-1 as an IFN-α-mediated key regulator potentially accounting for shared functional features between IFN-α DC and pDC.
IFN-α Regulates Blimp-1 Expression via miR-23a and miR-125b in Both Monocytes-Derived DC and pDC
Parlato, Stefania; Salerno, Debora; Marcantonio, Cinzia; Borghi, Paola; Tataseo, Paola; Ciccaglione, Anna Rita; Presutti, Carlo; Romagnoli, Giulia; Bozzoni, Irene; Belardelli, Filippo; Gabriele, Lucia
2013-01-01
Type I interferon (IFN-I) have emerged as crucial mediators of cellular signals controlling DC differentiation and function. Human DC differentiated from monocytes in the presence of IFN-α (IFN-α DC) show a partially mature phenotype and a special capability of stimulating CD4+ T cell and cross-priming CD8+ T cells. Likewise, plasmacytoid DC (pDC) are blood DC highly specialized in the production of IFN-α in response to viruses and other danger signals, whose functional features may be shaped by IFN-I. Here, we investigated the molecular mechanisms stimulated by IFN-α in driving human monocyte-derived DC differentiation and performed parallel studies on peripheral unstimulated and IFN-α-treated pDC. A specific miRNA signature was induced in IFN-α DC and selected miRNAs, among which miR-23a and miR-125b, proved to be negatively associated with up-modulation of Blimp-1 occurring during IFN-α-driven DC differentiation. Of note, monocyte-derived IFN-α DC and in vitro IFN-α-treated pDC shared a restricted pattern of miRNAs regulating Blimp-1 expression as well as some similar phenotypic, molecular and functional hallmarks, supporting the existence of a potential relationship between these DC populations. On the whole, these data uncover a new role of Blimp-1 in human DC differentiation driven by IFN-α and identify Blimp-1 as an IFN-α-mediated key regulator potentially accounting for shared functional features between IFN-α DC and pDC. PMID:23977359
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-11
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 74 [Docket No. FDA-2011-C-0050] D&C Red No. 6 and D&C Red No. 7; Change in Specification; Confirmation of Effective... the requirements for D&C Red No. 6 and D&C Red No. 7 by replacing the current specification for...
ERIC Educational Resources Information Center
Silva-Ortigoza, R.; Silva-Ortigoza, G.; Hernandez-Guzman, V. M.; Saldana-Gonzalez, G.; Marcelino-Aranda, M.; Marciano-Melchor, M.
2012-01-01
We introduce a dc/dc boost power converter as a didactic prototype intended to support courses on electric circuit analysis experimentally. The corresponding mathematical model is obtained, the converter is designed and an experimental setup is described, constructed and tested. Simplicity of construction as well as low cost of components renders…
14 CFR 93.339 - Requirements for operating in the DC SFRA, including the DC FRZ.
Code of Federal Regulations, 2010 CFR
2010-01-01
... aircraft in the DC SFRA, including the DC FRZ, the pilot obtains and transmits a discrete transponder code... flight plan by obtaining a discrete transponder code. The flight plan is closed upon landing at an... transmitting an Air Traffic Control-assigned discrete transponder code. (c) When operating an aircraft in the...
A Single-Phase Embedded Z-Source DC-AC Inverter
Kim, Se-Jin; Lim, Young-Cheol
2014-01-01
In the conventional DC-AC inverter consisting of two DC-DC converters with unipolar output capacitors, the output capacitor voltages of the DC-DC converters must be higher than the DC input voltage. To overcome this weakness, this paper proposes a single-phase DC-AC inverter consisting of two embedded Z-source converters with bipolar output capacitors. The proposed inverter is composed of two embedded Z-source converters with a common DC source and output AC load. Though the output capacitor voltages of the converters are relatively low compared to those of a conventional inverter, an equivalent level of AC output voltages can be obtained. Moreover, by controlling the output capacitor voltages asymmetrically, the AC output voltage of the proposed inverter can be higher than the DC input voltage. To verify the validity of the proposed inverter, experiments were performed with a DC source voltage of 38 V. By controlling the output capacitor voltages of the converters symmetrically or asymmetrically, the proposed inverter can produce sinusoidal AC output voltages. The experiments show that efficiencies of up to 95% and 97% can be achieved with the proposed inverter using symmetric and asymmetric control, respectively. PMID:25133241
A single-phase embedded Z-source DC-AC inverter.
Kim, Se-Jin; Lim, Young-Cheol
2014-01-01
In the conventional DC-AC inverter consisting of two DC-DC converters with unipolar output capacitors, the output capacitor voltages of the DC-DC converters must be higher than the DC input voltage. To overcome this weakness, this paper proposes a single-phase DC-AC inverter consisting of two embedded Z-source converters with bipolar output capacitors. The proposed inverter is composed of two embedded Z-source converters with a common DC source and output AC load. Though the output capacitor voltages of the converters are relatively low compared to those of a conventional inverter, an equivalent level of AC output voltages can be obtained. Moreover, by controlling the output capacitor voltages asymmetrically, the AC output voltage of the proposed inverter can be higher than the DC input voltage. To verify the validity of the proposed inverter, experiments were performed with a DC source voltage of 38 V. By controlling the output capacitor voltages of the converters symmetrically or asymmetrically, the proposed inverter can produce sinusoidal AC output voltages. The experiments show that efficiencies of up to 95% and 97% can be achieved with the proposed inverter using symmetric and asymmetric control, respectively.
Bidirectional dc-to-dc Power Converter
NASA Technical Reports Server (NTRS)
Griesbach, C. R.
1986-01-01
Solid-state, series-resonant converter uses high-voltage thyristors. Converter used either to convert high-voltage, low-current dc power to lowvoltage, high current power or reverse. Taking advantage of newly-available high-voltage thyristors to provide better reliability and efficiency than traditional converters that use vacuum tubes as power switches. New converter essentially maintenance free and provides greatly increased mean time between failures. Attractive in industrial applications whether or not bidirectional capability is required.
Simultaneous distribution of AC and DC power
Polese, Luigi Gentile
2015-09-15
A system and method for the transport and distribution of both AC (alternating current) power and DC (direct current) power over wiring infrastructure normally used for distributing AC power only, for example, residential and/or commercial buildings' electrical wires is disclosed and taught. The system and method permits the combining of AC and DC power sources and the simultaneous distribution of the resulting power over the same wiring. At the utilization site a complementary device permits the separation of the DC power from the AC power and their reconstruction, for use in conventional AC-only and DC-only devices.
Low-to-Medium Power Single Chip Digital Controlled DC-DC Regulator for Point-of-Load Applications
NASA Technical Reports Server (NTRS)
Adell, Philippe C. (Inventor); Bakkaloglu, Bertan (Inventor); Vermeire, Bert (Inventor); Liu, Tao (Inventor)
2015-01-01
A DC-DC converter for generating a DC output voltage includes: a digitally controlled pulse width modulator (DPWM) for controlling a switching power stage to supply a varying voltage to an inductor; and a digital voltage feedback circuit for controlling the DPWM in accordance with a feedback voltage corresponding to the DC output voltage, the digital voltage feedback circuit including: a first voltage controlled oscillator for converting the feedback voltage into a first frequency signal and to supply the first frequency signal to a first frequency discriminator; a second voltage controlled oscillator for converting a reference voltage into a second frequency signal and to supply the second frequency signal to a second frequency discriminator; a digital comparator for comparing digital outputs of the first and second frequency discriminators and for outputting a digital feedback signal; and a controller for controlling the DPWM in accordance with the digital feedback signal.
NASA Astrophysics Data System (ADS)
Abe, Takahiro; Tan, Nadia Mei Lin; Akagi, Hirofumi
This paper presents an experimental discussion on a 6-kW, full-bridge, zero-voltage switching bidirectional isolated dc/dc converter for a 53.2-V, 2-kWh Li-ion battery energy storage system. The combination of high-frequency switching devices, 600-V/200-A IGBTs and 100-V/500-A MOSFETs with a high-frequency transformer reduces the weight and physical size of the bidirectional isolated dc/dc converter. The dc voltage on the high-voltage side of the converter is controlled in a range of 300V to 355V as the battery voltage on the low-voltage side varies from 50V to 59V. Experimental verification of bidirectional power flow into (battery charging) or out of (battery discharging) the Li-ion battery bank is also presented. The maximal efficiency of the dc/dc converter is measured to be 98.1% during charging and 98.2% during discharging, excluding the gate drive loss and control circuit loss.
NASA Technical Reports Server (NTRS)
Huffman, S. D.; Burns, W. W., III; Wilson, T. G.; Owen, H. A., Jr.
1976-01-01
Implementations of a state-plane-trajectory control law for energy storage dc-to-dc converters are presented. Performance characteristics of experimental voltage step-up converter systems employing these implementations are reported and compared to theoretical predictions.
Saikia, Beenita; Barua, Chandana Choudhury; Haloi, Prakash; Patowary, Pompy
2017-01-01
The aim of this study was to evaluate anticholinergic, antihistaminic, and antiserotonergic activity of the n-hexane extract of the seeds of Zanthoxylum alatum (ZAHE) on isolated ileum of rat and guinea pig and fundus of rat. ZAHE was prepared using soxhlet extraction and cumulative concentration response curves were constructed using various doses on the tissues for acetylcholine (ACh), 5-hydroxytryptamine (5-HT), and histamine with or without n-hexane extract. Atropine, ketanserin, and pheniramine maleate were used as antagonists for ACh, serotonin, and histamine, respectively. ZAHE-induced concentration-dependent inhibition of isolated ileum and fundus in rat and ileum of guinea pig. The half maximal effective concentration (EC 50 ) of ACh in the presence of atropine (10 -6 M; P < 0.05) and ZAHE (1000 μg/ml; P < 0.01) was significantly higher than EC 50 of ACh alone. The EC 50 of 5-HT in the presence of ketanserin (10 -5 M; P < 0.01) and ZAHE (1000 μg/ml; P < 0.05) was higher than EC 50 of 5-HT alone. Similarly, the EC 50 of histamine in the presence of pheniramine maleate (10 -6 M; P < 0.01) and ZAHE (300 μg/ml; P < 0.01 and 1000 μg/ml; P < 0.05) was also significantly higher than EC 50 of histamine alone. From the study, it was observed that ZAHE shows significant anticholinergic, antiserotonergic, and antihistaminic activity. The study provides sufficient evidence that the seeds can be used in gastric disorders, cough, chest infection, etc., as per folklore claims.
Fast-response free-running dc-to-dc converter employing a state-trajectory control law
NASA Technical Reports Server (NTRS)
Huffman, S. D.; Burns, W. W., III; Wilson, T. G.; Owen, H. A., Jr.
1977-01-01
A recently proposed state-trajectory control law for a family of energy-storage dc-to-dc converters has been implemented for the voltage step-up configuration. Two methods of realization are discussed; one employs a digital processor and the other uses analog computational circuits. Performance characteristics of experimental voltage step-up converters operating under the control of each of these implementations are reported and compared to theoretical predictions and computer simulations.
Recovering DC coefficients in block-based DCT.
Uehara, Takeyuki; Safavi-Naini, Reihaneh; Ogunbona, Philip
2006-11-01
It is a common approach for JPEG and MPEG encryption systems to provide higher protection for dc coefficients and less protection for ac coefficients. Some authors have employed a cryptographic encryption algorithm for the dc coefficients and left the ac coefficients to techniques based on random permutation lists which are known to be weak against known-plaintext and chosen-ciphertext attacks. In this paper we show that in block-based DCT, it is possible to recover dc coefficients from ac coefficients with reasonable image quality and show the insecurity of image encryption methods which rely on the encryption of dc values using a cryptoalgorithm. The method proposed in this paper combines dc recovery from ac coefficients and the fact that ac coefficients can be recovered using a chosen ciphertext attack. We demonstrate that a method proposed by Tang to encrypt and decrypt MPEG video can be completely broken.
Atmospheric Science Data Center
2015-03-16
Deep Convective Clouds and Chemistry (DC3) Data and Information The Deep Convective Clouds and Chemistry ( DC3 ) field campaign is investigating the impact of deep, ... processes, on upper tropospheric (UT) composition and chemistry. The primary science objectives are: To quantify and ...
He, Fengyuan; Li, Dengwu; Wang, Dongmei; Deng, Ming
2016-07-01
In this study, an aqueous two-phase system (ATPS) based on ethanol/NaH2 PO4 was developed for the extraction and purification of quercitrin, hyperoside, rutin, and afzelin from Zanthoxylum bungeanum Maxim leaves. These 4 flavonoids were 1st extracted from dried Z. bungeanum leaves using a 60% ethanol solution and subsequently added to the ATPS for further purification. The partition behavior of the 4 flavonoids in ATPS was investigated. The optimal ATPS conditions were: 29% (w/w) NaH2 PO4 , 25% (w/w) ethanol concentration, 1% (w/w) added amount of leaf extracts, no pH adjustment, and repeated 1 h extractions at 25 °C. Under the optimal conditions for the 10 g ATPS, the absolute recovery of quercitrin, hyperoside, rutin, and afzelin reached 90.3%, 83.5%, 92.3%, and 89.1%, respectively. Compared to the 60% ethanol extracts, the content of quercitrin (44.8 mg/g), hyperoside (65.6 mg/g), rutin (56.4 mg/g), and afzelin (6.84 mg/g) in the extracts increased by 49.9%, 38.8%, 45.6%, and 36.8% respectively. The extracts after ATPS also exhibited stronger antioxidant activities, the 2,2-diphenyl-1-picrylhydrazyl IC50 value (10.5 μg/mL) decreased by 41.8%, and the 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt value (966 μmol Trolox/g) and ferric reducing power value (619 μmol Trolox/g) increased by 29.8% and 53.7%, respectively. Furthermore, scale-up experiments indicated that a larger scale experiment was feasible for the purification of the 4 flavonoids. © 2016 Institute of Food Technologists®
Low Temperature Performance of High Power Density DC/DC Converter Modules
NASA Technical Reports Server (NTRS)
Elbuluk, Malik E.; Hammond, Ahmad; Gerber, Scott; Patterson, Richard L.; Overton, Eric
2001-01-01
In this paper, two second-generation high power density DC/DC converter modules have been evaluated at low operating temperatures. The power rating of one converter (Module 1) was specified at 150 W with an input voltage range of 36 to 75 V and output voltage of 12 V. The other converter (Module 2) was specified at 100 W with the same input voltage range and an output voltage of 3.3 V. The converter modules were evaluated in terms of their performance as a function of operating temperature in the range of 25 to -140 C. The experimental procedures along with the experimental data obtained are presented and discussed in this paper.
"DC:0-3" to "DC:0-3R" to "DC:0-5": A New Edition
ERIC Educational Resources Information Center
Zeanah, Charles H., Jr.; Carter, Alice; Cohen, Julie; Egger, Helen; Keren, Miri; Gleason, Mary Margaret; Lieberman, Alicia F.; Mulrooney, Kathleen; Oser, Cindy
2015-01-01
Originally published in 1994 by ZERO TO THREE as the "Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood" ("DC:0-3") and revised in 2005 by ZERO TO THREE as the "Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, Revised…
Dual wound dc brush motor gearhead
NASA Technical Reports Server (NTRS)
Henson, Barrie W.
1986-01-01
The design requirements, the design, development tests and problems, the qualification and life test and the findings of the strip examination of a dual wound DC brushed motor gearhead are described. It is the only space qualified dual wound dc brushed motor gearhead in Europe.
RANKL-induced DC-STAMP Is Essential for Osteoclastogenesis
Kukita, Toshio; Wada, Naohisa; Kukita, Akiko; Kakimoto, Takashi; Sandra, Ferry; Toh, Kazuko; Nagata, Kengo; Iijima, Tadahiko; Horiuchi, Madoka; Matsusaki, Hiromi; Hieshima, Kunio; Yoshie, Osamu; Nomiyama, Hisayuki
2004-01-01
Osteoclasts are bone-resorbing, multinucleated giant cells that are essential for bone remodeling and are formed through cell fusion of mononuclear precursor cells. Although receptor activator of nuclear factor–κB ligand (RANKL) has been demonstrated to be an important osteoclastogenic cytokine, the cell surface molecules involved in osteoclastogenesis are mostly unknown. Here, we report that the seven-transmembrane receptor-like molecule, dendritic cell–specific transmembrane protein (DC-STAMP) is involved in osteoclastogenesis. Expression of DC-STAMP is rapidly induced in osteoclast precursor cells by RANKL and other osteoclastogenic stimulations. Targeted inhibition of DC-STAMP by small interfering RNAs and specific antibody markedly suppressed the formation of multinucleated osteoclast-like cells. Overexpression of DC-STAMP enhanced osteoclastogenesis in the presence of RANKL. Furthermore, DC-STAMP directly induced the expression of the osteoclast marker tartrate-resistant acid phosphatase. These data demonstrate for the first time that DC-STAMP has an essential role in osteoclastogenesis. PMID:15452179
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-23
...: We propose to adopt a new airworthiness directive (AD) for all Model DC-9-81 (MD-81), DC-9-82 (MD-82... inspections for cracking of the left and right upper center skin panels of the horizontal stabilizer, and..., West Building Ground Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC 20590. Hand...
Zhou, Xue; O'Donnell, Kerry; Aoki, Takayuki; Smith, Jason A; Kasson, Matthew T; Cao, Zhi-Min
2016-01-01
Canker disease of prickly ash (Zanthoxylum bungeanum) has caused a decline in the production of this economically important spice in northern China in the past 25 y. To identify the etiological agent, 38 fungal isolates were recovered from symptomatic tissues from trees in five provinces in China. These isolates were identified by conducting BLASTN queries of NCBI GenBank and phylogenetic analyses of DNA sequence data from the nuclear ribosomal internal transcribed spacer region (ITS rDNA), a portion of the translation elongation factor 1-α (TEF1) gene, and genes encoding RNA polymerase II largest (RPB1) and second largest (RPB2) subunits. Results of these analyses suggested that 30/38 isolates belonged to two novel fusaria most closely related to the Florida torreya (Torreya taxifolia Arn.) pathogen, Fusarium torreyae in Florida and Georgia. These three canker-inducing tree pathogens form a novel clade within Fusarium here designated the F. torreyae species complex (FTOSC). BLASTN queries of GenBank also revealed that 5/38 isolates recovered from cankers represented an undescribed phylogenetic species within the F. solani species complex (FSSC) designated FSSC 6. Stem inoculations of three fusaria on Z. bungeanum resulted in consistent canker symptoms from which these three fusaria were recovered. The two novel fusaria, however, induced significantly larger lesions than FSSC 6. Herein, the two novel prickly ash pathogens are formally described as F. zanthoxyli and F. continuum. © 2016 by The Mycological Society of America.
SSP Technology Investigation of a High-Voltage DC-DC Converter
NASA Technical Reports Server (NTRS)
Pappas, J. A.; Grady, W. M.; George, Patrick J. (Technical Monitor)
2002-01-01
The goal of this project was to establish the feasibility of a high-voltage DC-DC converter based on a rod-array triggered vacuum switch (RATVS) for the Space Solar Power system. The RATVS has many advantages over silicon and silicon-carbide devices. The RATVS is attractive for this application because it is a high-voltage device that has already been demonstrated at currents in excess of the requirement for an SSP device and at much higher per-device voltages than existing or near-term solid state switching devices. The RATVS packs a much higher specific power rating than any solid-state device and it is likely to be more tolerant of its surroundings in space. In addition, pursuit of an RATVS-based system would provide NASA with a nearer-term and less expensive power converter option for the SSP.
Shimer, D.W.; Lange, A.C.
1995-05-23
A high-power power supply produces a controllable, constant high voltage output under varying and arcing loads. The power supply includes a voltage regulator, an inductor, an inverter for producing a high frequency square wave current of alternating polarity, an improved inverter voltage clamping circuit, a step up transformer, an output rectifier for producing a dc voltage at the output of each module, and a current sensor for sensing output current. The power supply also provides dynamic response to varying loads by controlling the voltage regulator duty cycle and circuitry is provided for sensing incipient arc currents at the output of the power supply to simultaneously decouple the power supply circuitry from the arcing load. The power supply includes a plurality of discrete switching type dc--dc converter modules. 5 Figs.
Shimer, Daniel W.; Lange, Arnold C.
1995-01-01
A high-power power supply produces a controllable, constant high voltage output under varying and arcing loads. The power supply includes a voltage regulator, an inductor, an inverter for producing a high frequency square wave current of alternating polarity, an improved inverter voltage clamping circuit, a step up transformer, an output rectifier for producing a dc voltage at the output of each module, and a current sensor for sensing output current. The power supply also provides dynamic response to varying loads by controlling the voltage regulator duty cycle and circuitry is provided for sensing incipient arc currents at the output of the power supply to simultaneously decouple the power supply circuitry from the arcing load. The power supply includes a plurality of discrete switching type dc--dc converter modules.
NASA DC-8 Airborne Scanning Lidar Sensor Development
NASA Technical Reports Server (NTRS)
Nielsen, Norman B.; Uthe, Edward E.; Kaiser, Robert D.; Tucker, Michael A.; Baloun, James E.; Gorordo, Javier G.
1996-01-01
The NASA DC-8 aircraft is used to support a variety of in-situ and remote sensors for conducting environmental measurements over global regions. As part of the atmospheric effects of aviation program (AEAP) the DC-8 is scheduled to conduct atmospheric aerosol and gas chemistry and radiation measurements of subsonic aircraft contrails and cirrus clouds. A scanning lidar system is being developed for installation on the DC-8 to support and extend the domain of the AEAP measurements. Design and objectives of the DC-8 scanning lidar are presented.
Characteristics of DC electric fields at dipolarization fronts
NASA Astrophysics Data System (ADS)
Laakso, Harri; Escoubet, Philippe; Masson, Arnaud
2016-04-01
We investigate the characteristics of DC electric field at dipolarization fronts and BBF's using multi-point Cluster observations. There are plenty of important issues that are considered, such as what kind of DC electric fields exist in such events and what are their spatial scales. One can also recognize if electrons and ions perform ExB drift motions in these events. To investigate this, we take an advantage of five different DC electric field measurements in the plasma sheet available from the EFW double probe experiment, EDI electron drift instrument, CODIF and HIA ion spectrometers, and PEACE electron spectrometer. The calibrated observations of the three spectrometers are used to determine the proton and electron drift velocity and furthermore the DC electric field, assuming that the electron and proton velocity perpendicular to the magnetic field is dominated by the ExB drift motion. Naturally when ions and electrons do not perform a proper drift motion, which can happen in the plasma sheet, the estimated DC electric field from ion and electron motion is not correct. However, surprisingly often the DC electric fields estimated from electron and ion motions are identical suggesting that this field is a real DC electric field around the measurement point. This investigation also helps understand how well different measurements are calibrated.
A 10 kW dc-dc converter using IGBTs with active snubbers. [Insulated Gate Bipolar Transistor
NASA Technical Reports Server (NTRS)
Masserant, Brian J.; Shriver, Jeffrey L.; Stuart, Thomas A.
1993-01-01
This full bridge dc-dc converter employs zero voltage switching (ZVS) on one leg and zero current switching (ZCS) on the other. This technique produces exceptionally low IGBT switching losses through the use of an active snubber that recycles energy back to the source. Experimental results are presented for a 10 kW, 20 kHz converter.
Simultaneous DC and three phase output using hybrid converter
NASA Astrophysics Data System (ADS)
Surenderanath, S.; Rathnavel, P.; Prakash, G.; Rayavel, P.
2018-04-01
This Paper introduces new hybrid converter topologies which can supply simultaneously three phase AC as well as DC from a single DC source. The new Hybrid Converter is derived from the single switch controlled Boost converter by replacing the controlled switch with voltage source inverter (VSI). This new hybrid converter has the advantages like reduced number of switches as compared with conventional design having separate converter for supplying three phase AC and DC loads, provide DC and three AC outputs with an increased reliability, resulting from the inherent shoot through protection in the inverter stage. The proposed converter, studied in this paper, is called Boost-Derived Hybrid Converter (BDHC) as it is obtained from the conventional boost topology. A DSPIC based feedback controller is designed to regulate the DC as well as AC outputs. The proposed Converter can supply DC and AC loads at 95 V and 35 V (line to ground) respectively from a 48 V DC source.
A soft-switching coupled inductor bidirectional DC-DC converter with high-conversion ratio
NASA Astrophysics Data System (ADS)
Chao, Kuei-Hsiang; Jheng, Yi-Cing
2018-01-01
A soft-switching bidirectional DC-DC converter is presented herein as a way to improve the conversion efficiency of a photovoltaic (PV) system. Adoption of coupled inductors enables the presented converter not only to provide a high-conversion ratio but also to suppress the transient surge voltage via the release of the energy stored in leakage flux of the coupled inductors, and the cost can kept down consequently. A combined use of a switching mechanism and an auxiliary resonant branch enables the converter to successfully perform zero-voltage switching operations on the main switches and improves the efficiency accordingly. It was testified by experiments that our proposed converter works relatively efficiently in full-load working range. Additionally, the framework of the converter intended for testifying has high-conversion ratio. The results of a test, where a generating system using PV module array coupled with batteries as energy storage device was used as the low-voltage input side, and DC link was used as high-voltage side, demonstrated our proposed converter framework with high-conversion ratio on both high-voltage and low-voltage sides.
Solar Photovoltaic DC Systems: Basics and Safety: Preprint
DOE Office of Scientific and Technical Information (OSTI.GOV)
McNutt, Peter F; Sekulic, William R; Dreifuerst, Gary
Solar Photovoltaic (PV) systems are common and growing with 42.4 GW installed capacity in U.S. (almost 15 GW added in 2016). This paper will help electrical workers, and emergency responders understand the basic operating principles and hazards of PV DC arrays. We briefly discuss the following aspects of solar photovoltaic (PV) DC systems: the effects of solar radiation and temperature on output power; PV module testing standards; common system configurations; a simple PV array sizing example; NEC guidelines and other safety features; DC array commissioning, periodic maintenance and testing; arc-flash hazard potential; how electrical workers and emergency responders can andmore » do work safely around PV arrays; do moonlight and artificial lighting pose a real danger; typical safe operating procedures; and other potential DC-system hazards to be aware of. We also present some statistics on PV DC array electrical incidents and injuries. Safe PV array operation is possible with a good understanding of PV DC arrays basics and having good safe operating procedures in place.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-25
... Airworthiness Limitations inspections (ALIs). This proposed AD results from a design review of the fuel tank...,'' and also adds ALI 30-1 for a pneumatic system decay check to minimize the risk of hot air impingement... 5, 2010, adds ALI 28-1, ``DC-8 Alternate and Center Auxiliary Tank Fuel Pump Control Systems Check...
Historical Material Analysis of DC745U Pressure Pads
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ortiz-Acosta, Denisse
As part of the Enhance Surveillance mission, it is the goal to provide suitable lifetime assessment of stockpile materials. This report is an accumulation of historical publication on the DC745U material and their findings. It is the intention that the B61 LEP program uses this collection of data to further develop their understanding and potential areas of study. DC745U is a commercially available silicone elastomer consisting of dimethyl, methyl-phenyl, and methyl-vinyl siloxane repeat units. Originally, this material was manufactured by Dow Corning as Silastic{reg_sign} DC745U at their manufacturing facility in Kendallville, IN. Recently, Dow Corning shifted this material to themore » Xiameter{reg_sign} brand product line. Currently, DC745U is available through Xiameter{reg_sign} or Dow Corning's distributor R. D. Abbott Company. DC745U is cured using 0.5 wt% vinyl-specific peroxide curing agent known as Luperox 101 or Varox DBPH-50. This silicone elastomer is used in numerous parts, including two major components (outer pressure pads and aft cap support) in the W80 and as pressure pads on the B61. DC745U is a proprietary formulation, thus Dow Corning provides limited information on its composition and properties. Based on past experience with Dow Corning, DC745U is at risk of formulation changes without notification to the costumer. A formulation change for DC745U may have a significant impact because the network structure is a key variable in determining material properties. The purpose of this report is to provide an overview of historical DC745U studies and identify gaps that need to be addressed in future work. Some of the previous studies include the following: 1. Spectroscopic characterization of raw gum stock. 2. Spectroscopic, thermal, and mechanical studies on cured DC745U. 3. Nuclear Magnetic Resonance (NMR) and solvent swelling studies on DC745U with different crosslink densities. 4. NMR, solvent swelling, thermal, and mechanical studies on
NASA Technical Reports Server (NTRS)
Huffman, S.
1977-01-01
Detailed instructions on the use of two computer-aided-design programs for designing the energy storage inductor for single winding and two winding dc to dc converters are provided. Step by step procedures are given to illustrate the formatting of user input data. The procedures are illustrated by eight sample design problems which include the user input and the computer program output.
A Compact, Soft-Switching DC-DC Converter for Electric Propulsion
NASA Technical Reports Server (NTRS)
Button, Robert; Redilla, Jack; Ayyanar, Raja
2003-01-01
A hybrid, soft-switching, DC-DC converter has been developed with superior soft switching characteristics, high efficiency, and low electro-magnetic interference. This hybrid topology is comprised of an uncontrolled bridge operating at full pulse-width, and a controlled section operating as a conventional phase modulated converter. The unique topology is able to maintain zero voltage switching down to no load operating conditions. A breadboard prototype was developed and tested to demonstrate the benefits of the topology. Improvements were then made to reduce the size of passive components and increase efficiency in preparation for packaging. A packaged prototype was then designed and built, and several innovative packaging techniques are presented. Performance test data is presented that reveals deficiencies in the design of the power transformer. A simple redesign of the transformer windings eliminated the deficiency. Future plans to improve the converter and packaging design are presented along with several conclusions.
Saikia, Beenita; Barua, Chandana Choudhury; Haloi, Prakash; Patowary, Pompy
2017-01-01
Objectives: The aim of this study was to evaluate anticholinergic, antihistaminic, and antiserotonergic activity of the n-hexane extract of the seeds of Zanthoxylum alatum (ZAHE) on isolated ileum of rat and guinea pig and fundus of rat. Materials and Methods: ZAHE was prepared using soxhlet extraction and cumulative concentration response curves were constructed using various doses on the tissues for acetylcholine (ACh), 5-hydroxytryptamine (5-HT), and histamine with or without n-hexane extract. Atropine, ketanserin, and pheniramine maleate were used as antagonists for ACh, serotonin, and histamine, respectively. Results: ZAHE-induced concentration-dependent inhibition of isolated ileum and fundus in rat and ileum of guinea pig. The half maximal effective concentration (EC50) of ACh in the presence of atropine (10−6 M; P < 0.05) and ZAHE (1000 μg/ml; P < 0.01) was significantly higher than EC50of ACh alone. The EC50of 5-HT in the presence of ketanserin (10−5 M; P < 0.01) and ZAHE (1000 μg/ml; P < 0.05) was higher than EC50of 5-HT alone. Similarly, the EC50of histamine in the presence of pheniramine maleate (10−6 M; P < 0.01) and ZAHE (300 μg/ml; P < 0.01 and 1000 μg/ml; P < 0.05) was also significantly higher than EC50of histamine alone. Conclusion: From the study, it was observed that ZAHE shows significant anticholinergic, antiserotonergic, and antihistaminic activity. The study provides sufficient evidence that the seeds can be used in gastric disorders, cough, chest infection, etc., as per folklore claims. PMID:28458421
The dc power circuits: A compilation
NASA Technical Reports Server (NTRS)
1972-01-01
A compilation of reports concerning power circuits is presented for the dissemination of aerospace information to the general public as part of the NASA Technology Utilization Program. The descriptions for the electronic circuits are grouped as follows: dc power supplies, power converters, current-voltage power supply regulators, overload protection circuits, and dc constant current power supplies.
DC KIDS COUNT e-Databook Indicators
ERIC Educational Resources Information Center
DC Action for Children, 2012
2012-01-01
This report presents indicators that are included in DC Action for Children's 2012 KIDS COUNT e-databook, their definitions and sources and the rationale for their selection. The indicators for DC KIDS COUNT represent a mix of traditional KIDS COUNT indicators of child well-being, such as the number of children living in poverty, and indicators of…
ALA-PDT mediated DC vaccine for skin squamous cell carcinoma
NASA Astrophysics Data System (ADS)
Ji, Jie; Fan, Zhixia; Zhou, Feifan; Wang, Xiaojie; Shi, Lei; Zhang, Haiyan; Wang, Peiru; Yang, Degang; Zhang, Linglin; Wang, Xiuli; Chen, Wei R.
2015-03-01
Dendritic cell (DC) based vaccine has emerged as a promising immunotherapy for cancers. However, most DC vaccines so far have only achieved limited success in cancer treatment. Photodynamic therapy (PDT), an established cancer treatment strategy, can cause immunogenic apoptosis to induce an effective antitumor immune response. In this study, we developed a DC-based cancer vaccine using immunogenic apoptotic tumor cells induced by 5-aminolevulinic acid (ALA) mediated PDT. The maturation of DCs induced by PDT-treated apoptotic cells was evaluated. The anti-tumor immunity of ALA-PDT-DC vaccine was tested with mouse model. We observed the maturations of DCs potentiated by ALA-PDT treated tumor cells, including phenotypic maturation (upregulation of surface expression of MHC-II, DC80, and CD86), and functional maturation (enhanced capability to secret INF-Υ and IL-12). ALA-PDT-DC vaccine mediated by apoptotic cells provided protection against tumor in mice, far stronger than that of DC vaccine obtained from freeze/thaw treated tumor cells. Our results indicate that immunogenic apoptotic tumor cells can be more effective in enhancing DC-based cancer vaccine, which could improve the clinical application of PDT- DC vaccines.
NASA Technical Reports Server (NTRS)
Ohri, A. K.; Owen, H. A.; Wilson, T. G.; Rodriguez, G. E.
1974-01-01
The simulation of converter-controller combinations by means of a flexible digital computer program which produces output to a graphic display is discussed. The procedure is an alternative to mathematical analysis of converter systems. The types of computer programming involved in the simulation are described. Schematic diagrams, state equations, and output equations are displayed for four basic forms of inductor-energy-storage dc to dc converters. Mathematical models are developed to show the relationship of the parameters.
Hardy, Andrew W; Graham, David R; Shearer, Gene M; Herbeuval, Jean-Philippe
2007-10-30
Plasmacytoid dendritic cells (pDC) are key players in viral immunity and produce IFN-alpha after HIV-1 exposure, which in turn regulates TNF-related apoptosis-inducing ligand (TRAIL) expression by CD4(+) T cells. We show here that infectious and noninfectious HIV-1 virions induce activation of pDC into TRAIL-expressing IFN-producing killer pDC (IKpDC). IKpDC expressed high levels of activation markers (HLA-DR, CD80, CD83, and CD86) and the migration marker CCR7. Surprisingly, CXCR4 and CCR5 were down-regulated on IKpDC. We also show that HIV-1-induced IKpDC depended on Toll-like receptor 7 (TLR7) activation. HIV-1 or TLR7 agonistexposed IKpDC induced apoptosis of the CD4(+) T cell line SupT1 via the TRAIL pathway. Furthermore, IFN-alpha produced after HIV-induced TLR7 stimulation was responsible for TRAIL expression and the down-regulation of both CXCR4 and CCR5 by IKpDC. In contrast, activation and migration markers were not regulated by IFN-alpha. Finally, IFN-alpha increased the survival of IKpDC. We characterized a subset of pDC with a killer activity that is activated by endosomal-associated viral RNA and not by infection.
2004-03-17
NASA DC-8 Pilots Craig Bomben and Bill Brockett explain the DC-8 cockpit to Chilean students onboard the DC-8 aircraft at Carlos Ibanez del Campo International Airport in Punta Arenas, Chile. AirSAR 2004 is a three-week expedition by an international team of scientists that is using an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR) which is located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world including NASA's Jet Propulsion Laboratory are combining ground research done in several areas in Central and South America with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. In South America and Antarctica, AirSAR will collect imagery and data to help determine the contribution of Southern Hemisphere glaciers to sea level rise due to climate change. In Patagonia, researchers found this contribution had more than doubled from 1995 to 2000, compared to the previous 25 years. AirSAR data will make it possible to determine whether that trend is decreasing, continuing or accelerating. AirSAR will also provide reliable information on ice shelf thickness to measure the contribution of the glaciers to sea level.
Application of digital control techniques for satellite medium power DC-DC converters
NASA Astrophysics Data System (ADS)
Skup, Konrad R.; Grudzinski, Pawel; Nowosielski, Witold; Orleanski, Piotr; Wawrzaszek, Roman
2010-09-01
The objective of this paper is to present a work concerning a digital control loop system for satellite medium power DC-DC converters that is done in Space Research Centre. The whole control process of a described power converter bases on a high speed digital signal processing. The paper presents a development of a FPGA digital controller for voltage mode stabilization that was implemented using VHDL. The described controllers are a classical digital PID controller and a bang-bang controller. The used converter for testing is a simple model of 5-20 W, 200 kHz buck power converter. A high resolution digital PWM approach is presented. Additionally a simple and effective solution of filtering of an analog-to-digital converter output is presented.
A brief review of models of DC-DC power electronic converters for analysis of their stability
NASA Astrophysics Data System (ADS)
Siewniak, Piotr; Grzesik, Bogusław
2014-10-01
A brief review of models of DC-DC power electronic converters (PECs) is presented in this paper. It contains the most popular, continuous-time and discrete-time models used for PEC simulation, design, stability analysis and other applications. Both large-signal and small-signal models are considered. Special attention is paid to models that are used in practice for the analysis of the global and local stability of PECs.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-19
... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-698 (Enforcement Proceeding)] Certain DC-DC Controllers and Products Containing Same; Decision To Affirm-in-Part, Reverse-in-Part, Modify-in... 1930, as amended, 19 U.S.C. 1337, and in section 210.75 of the Commission's Rules of Practice and...
Influence of Random DC Offsets on Burst-Mode Receiver Sensitivity
NASA Astrophysics Data System (ADS)
Ossieur, Peter; de Ridder, Tine; Qiu, Xing-Zhi; Vandewege, Jan
2006-03-01
This paper presents the influence of random direct current (dc) offsets on the sensitivity of dc-coupled burst-mode receivers (BMRxs). It is well known that a BMRx exhibits a noisy decision threshold, resulting in a sensitivity penalty. If the BMRx is dc coupled, an additional penalty is incurred by random dc offsets. This penalty can only be determined for a statistically significant number of fabricated BMRx samples. Using Monte Carlo (MC) simulations and a detailed BMRx model, the relationship between the variance of this random dc offset, the resulting sensitivity penalty, and BMRx yield (the fraction of fabricated BMRx samples that meets a given sensitivity specification) is evaluated as a function of various receiver parameters. The obtained curves can be used to trade off BMRx die area against sensitivity for a given yield. It is demonstrated that a thorough understanding of the relationship between BMRx sensitivity, BMRx yield, and the variance of the random dc offsets is needed to optimize a dc-coupled BMRx with respect to sensitivity and die area for a given yield. It is shown that compensation of dc offsets with a resolution of 8 bits results in a sensitivity penalty of 1 dB for a wide range of random dc offsets.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-06
... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-698] In the Matter of Certain DC-DC Controllers and Products Containing Same; Notice of Commission Decision Not to Review the Administrative Law... Tariff Act of 1930, as amended (19 U.S.C. 1337), and in section 210.42 of the Commission's Rules of...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-26
... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-698] In the Matter of Certain DC-DC Controllers and Products Containing Same; Notice of Commission Decision Not To Review an Initial Determination..., as amended (19 U.S.C. 1337), and in sections 210.21(b) and 210.42 of the Commission's Rules of...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-26
... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-698] In the Matter of Certain DC-DC Controllers and Products Containing Same; Notice of Commission Decision Not To Review an Initial Determination..., as amended (19 U.S.C. 1337), and in sections 210.21(b) and 210.42 of the Commission's Rules of...
Washington, D.C. | Midmarket Solar Policies in the United States | Solar
Community Solar in the District of Columbia DC Sun: Community Solar Programs and incentives Department of Choice DC DC Sun: Solar Incentives Other DC Sun District of Columbia Sustainable Energy Utility
The Dylos DC1100 air quality monitor measures particulate matter (PM) to provide a continuous assessment of indoor air quality. The unit counts particles in two size ranges: large and small. According to the manufacturer, large particles have diameters between 2.5 and 10 micromet...
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2010-05-20
... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-698] In the Matter of: Certain DC-DC Controllers and Products Containing Same; Notice of Commission Decision Not To Review the Administrative Law... determination is contained in section 337 of the Tariff Act of 1930, as amended (19 U.S.C. 1337), and in section...
DC motor speed control using fuzzy logic controller
NASA Astrophysics Data System (ADS)
Ismail, N. L.; Zakaria, K. A.; Nazar, N. S. Moh; Syaripuddin, M.; Mokhtar, A. S. N.; Thanakodi, S.
2018-02-01
The automatic control has played a vital role in the advance of engineering and science. Nowadays in industries, the control of direct current (DC) motor is a common practice thus the implementation of DC motor controller speed is important. The main purpose of motor speed control is to keep the rotation of the motor at the present speed and to drive a system at the demand speed. The main purpose of this project is to control speed of DC Series Wound Motor using Fuzzy Logic Controller (FLC). The expectation of this project is the Fuzzy Logic Controller will get the best performance compared to dc motor without controller in terms of settling time (Ts), rise time (Tr), peak time (Tp) and percent overshoot (%OS).
Practical Design Guidelines of qZSI Based Step-Up DC/DC Converter
NASA Astrophysics Data System (ADS)
Zakis, Janis; Vinnikov, Dmitri; Roasto, Indrek; Jalakas, Tanel
2010-01-01
This paper presents some design guidelines for a new voltage fed step-up DC/DC isolated converter. The most significant advantage of proposed converter is voltage buck-boost operation on single stage. The most promising application for proposed converter is in the field of distributed power generation e.g. fuel cells or photovoltaic. The most sensitive issues - such as power losses caused by high currents in the input side of converter and high transient overvoltages across the inverter bridge caused by stray inductances were discussed and solved. The proposals and recommendations to overcome these issues are given in the paper. The Selection and design guidelines of converter elements are proposed and explained. The prototype of proposed converter was built and experimentally tested. Some results are presented and evaluated.
DC-STAMP Is an Osteoclast Fusogen Engaged in Periodontal Bone Resorption
Wisitrasameewong, W.; Kajiya, M.; Movila, A.; Rittling, S.; Ishii, T.; Suzuki, M.; Matsuda, S.; Mazda, Y.; Torruella, M.R.; Azuma, M.M.; Egashira, K.; Freire, M.O.; Sasaki, H.; Wang, C.Y.; Han, X.; Taubman, M.A.; Kawai, T.
2017-01-01
Dendritic cell-specific transmembrane protein (DC-STAMP) plays a key role in the induction of osteoclast (OC) cell fusion, as well as DC-mediated immune regulation. While DC-STAMP gene expression is upregulated in the gingival tissue with periodontitis, its pathophysiological roles in periodontitis remain unclear. To evaluate the effects of DC-STAMP in periodontitis, anti-DC-STAMP–monoclonal antibody (mAb) was tested in a mouse model of ligature-induced periodontitis (n = 6–7/group) where Pasteurella pneumotropica (Pp)-reactive immune response activated T cells to produce receptor activator of nuclear factor kappa-B ligand (RANKL), which, in turn, promotes the periodontal bone loss via upregulation of osteoclastogenesis. DC-STAMP was expressed on the cell surface of mature multinuclear OCs, as well as immature mononuclear OCs, in primary cultures of RANKL-stimulated bone marrow cells. Anti-DC-STAMP-mAb suppressed the emergence of large, but not small, multinuclear OCs, suggesting that DC-STAMP is engaged in the late stage of cell fusion. Anti-DC-STAMP-mAb also inhibited pit formation caused by RANKL-stimulated bone marrow cells. Attachment of ligature to a second maxillary molar induced DC-STAMP messenger RNA and protein, along with elevated tartrate-resistant acid phosphatase–positive (TRAP+) OCs and alveolar bone loss. As we expected, systemic administration of anti-DC-STAMP-mAb downregulated the ligature-induced alveolar bone loss. Importantly, local injection of anti-DC-STAMP-mAb also suppressed alveolar bone loss and reduced the total number of multinucleated TRAP+ cells in mice that received ligature attachment. Attachment of ligature induced significantly elevated tumor necrosis factor–α, interleukin-1β, and RANKL in the gingival tissue compared with the control site without ligature (P < 0.05), which was unaffected by local injection with either anti-DC-STAMP-mAb or control-mAb. Neither in vivo anti-Pp IgG antibody nor in vitro anti-Pp T
Hwang, In Sun; Choi, Du Seok; Kim, Nak Hyun; Kim, Dae Sung; Hwang, Byung Kook
2014-01-01
Plant defense against microbial pathogens is coordinated by a complex regulatory network. Cysteine/histidine-rich DC1 domain proteins mediate a variety of cellular processes involved in plant growth, development and stress responses. We identified a pepper (Capsicum annuum) cysteine/histidine-rich DC1 domain protein gene, CaDC1, which positively regulates plant defense during microbial infection, based on gene silencing and transient expression in pepper, as well as ectopic expression in Arabidopsis. Induction of CaDC1 by avirulent Xanthomonas campestris pv vesicatoria (Xcv) infection was pronounced at both transcriptional and translational levels in pepper leaves. Purified CaDC1 protein bound to both DNA and RNA in vitro, especially in the presence of Zn(2+). CaDC1 was localized to both the nucleus and the cytoplasm, which was required for plant cell death signaling. The nuclear localization of CaDC1 was dependent on the divergent C1 (DC1) domain. CaDC1 silencing in pepper conferred increased susceptibility to Xcv infection, which was accompanied by reduced salicylic acid accumulation and defense-related gene expression. Ectopic expression of CaDC1 in Arabidopsis enhanced resistance to Hyaloperonospora arabidopsidis. CaDC1 binds both RNA and DNA and functions as a positive regulator of plant cell death and SA-dependent defense responses. © 2013 The Authors. New Phytologist © 2013 New Phytologist Trust.
DC isolation and protection system and circuit
NASA Technical Reports Server (NTRS)
Wagner, Charles A. (Inventor); Kellogg, Gary V. (Inventor)
1991-01-01
A precision analog electronic circuit that is capable of sending accurate signals to an external device that has hostile electric characteristics, including the presence of very large common mode voltages. The circuit is also capable of surviving applications of normal mode overvoltages of up to 120 VAC/VDC for unlimited periods of time without damage or degradation. First, the circuit isolates the DC signal output from the computer. Means are then provided for amplifying the isolated DC signal. Further means are provided for stabilizing and protecting the isolating and amplifying means, and the isolated and amplified DC signal which is output to the external device, against overvoltages and overcurrents.
21 CFR 74.1206 - D&C Green No. 6.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Green No. 6. 74.1206 Section 74.1206 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1206 D&C Green No. 6. (a) Identity. The color additive D&C...
21 CFR 74.2307 - D&C Red No. 7
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2307 D&C Red No. 7 (a) Identity and specifications. The color additive D&C Red No. 7 shall conform in identity and specifications to the requirements of § 74.1307 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 7 may be safely used for...
21 CFR 74.2602 - D&C Violet No. 2.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2602 D&C Violet No. 2. (a) Identity and specifications. The color additive D&C Violet No. 2 shall conform in identity and specifications to the requirements of § 74.1602(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Violet No. 2 may be...
21 CFR 74.2306 - D&C Red No. 6.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...
21 CFR 74.2321 - D&C Red No. 21.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2321 D&C Red No. 21. (a) Identity and specifications. The color additive D&C Red No. 21 shall conform in identity and specifications to the requirements of § 74.1321(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 21 may be safely used for...
21 CFR 74.2322 - D&C Red No. 22.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2322 D&C Red No. 22. (a) Identity and specifications. The color additive D&C Red No. 22 shall conform in identity and specifications to the requirements of § 74.1322(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 22 may be safely used for...
21 CFR 82.1261 - D&C Orange No. 11.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 11. 82.1261 Section 82.1261 Food... CERTIFIED PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1261 D&C Orange No. 11. The color additive D&C Orange No. 11 shall conform in identity and specifications to the requirements...
21 CFR 82.1260 - D&C Orange No. 10.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 10. 82.1260 Section 82.1260 Food... CERTIFIED PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1260 D&C Orange No. 10. The color additive D&C Orange No. 10 shall conform in identity and specifications to the requirements...
21 CFR 74.2321 - D&C Red No. 21.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2321 D&C Red No. 21. (a) Identity and specifications. The color additive D&C Red No. 21 shall conform in identity and specifications to the requirements of § 74.1321(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 21 may be safely used for...
21 CFR 74.2307 - D&C Red No. 7
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2307 D&C Red No. 7 (a) Identity and specifications. The color additive D&C Red No. 7 shall conform in identity and specifications to the requirements of § 74.1307 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 7 may be safely used for...
21 CFR 74.2322 - D&C Red No. 22.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2322 D&C Red No. 22. (a) Identity and specifications. The color additive D&C Red No. 22 shall conform in identity and specifications to the requirements of § 74.1322(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 22 may be safely used for...
21 CFR 74.2322 - D&C Red No. 22.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2322 D&C Red No. 22. (a) Identity and specifications. The color additive D&C Red No. 22 shall conform in identity and specifications to the requirements of § 74.1322(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 22 may be safely used for...
21 CFR 74.2321 - D&C Red No. 21.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2321 D&C Red No. 21. (a) Identity and specifications. The color additive D&C Red No. 21 shall conform in identity and specifications to the requirements of § 74.1321(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 21 may be safely used for...
21 CFR 74.2321 - D&C Red No. 21.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2321 D&C Red No. 21. (a) Identity and specifications. The color additive D&C Red No. 21 shall conform in identity and specifications to the requirements of § 74.1321(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 21 may be safely used for...
21 CFR 74.2307 - D&C Red No. 7
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2307 D&C Red No. 7 (a) Identity and specifications. The color additive D&C Red No. 7 shall conform in identity and specifications to the requirements of § 74.1307 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 7 may be safely used for...
21 CFR 74.2306 - D&C Red No. 6.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...
21 CFR 74.2322 - D&C Red No. 22.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2322 D&C Red No. 22. (a) Identity and specifications. The color additive D&C Red No. 22 shall conform in identity and specifications to the requirements of § 74.1322(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 22 may be safely used for...
21 CFR 74.2306 - D&C Red No. 6.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...
21 CFR 74.2602 - D&C Violet No. 2.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2602 D&C Violet No. 2. (a) Identity and specifications. The color additive D&C Violet No. 2 shall conform in identity and specifications to the requirements of § 74.1602(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Violet No. 2 may be...
21 CFR 74.2602 - D&C Violet No. 2.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2602 D&C Violet No. 2. (a) Identity and specifications. The color additive D&C Violet No. 2 shall conform in identity and specifications to the requirements of § 74.1602(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Violet No. 2 may be...
21 CFR 74.2602 - D&C Violet No. 2.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2602 D&C Violet No. 2. (a) Identity and specifications. The color additive D&C Violet No. 2 shall conform in identity and specifications to the requirements of § 74.1602(a)(1) and (b). (b) Uses and restrictions. The color additive D&C Violet No. 2 may be...
21 CFR 74.2306 - D&C Red No. 6.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...
21 CFR 74.2307 - D&C Red No. 7
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2307 D&C Red No. 7 (a) Identity and specifications. The color additive D&C Red No. 7 shall conform in identity and specifications to the requirements of § 74.1307 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 7 may be safely used for...
The Fiscal Impact of the D.C. Voucher Program
ERIC Educational Resources Information Center
Aud, Susan L.; Michos, Leon
2006-01-01
In August 2004 the first ever federally funded school voucher program began in Washington, D.C. Eligible students could attend a private school of their choice in the District of Columbia. Each participant received up to $7,500 for school tuition, fees, and transportation. In addition, the D.C. Public School System (DCPS) and D.C. charter school…
Integrated-Circuit Controller For Brushless dc Motor
NASA Technical Reports Server (NTRS)
Le, Dong Tuan
1994-01-01
Generic circuit performs commutation-logic and power-switching functions for control of brushless dc motor. Controller includes commutation-logic and associated control circuitry, power supply, and inverters containing power transistors. Major advantages of controller are size, weight, and power consumption can be made less than other brushless-dc-motor controllers.
Medeiros, Renan Landau Paiva de; Barra, Walter; Bessa, Iury Valente de; Chaves Filho, João Edgar; Ayres, Florindo Antonio de Cavalho; Neves, Cleonor Crescêncio das
2018-02-01
This paper describes a novel robust decentralized control design methodology for a single inductor multiple output (SIMO) DC-DC converter. Based on a nominal multiple input multiple output (MIMO) plant model and performance requirements, a pairing input-output analysis is performed to select the suitable input to control each output aiming to attenuate the loop coupling. Thus, the plant uncertainty limits are selected and expressed in interval form with parameter values of the plant model. A single inductor dual output (SIDO) DC-DC buck converter board is developed for experimental tests. The experimental results show that the proposed methodology can maintain a desirable performance even in the presence of parametric uncertainties. Furthermore, the performance indexes calculated from experimental data show that the proposed methodology outperforms classical MIMO control techniques. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.
Applications of DC-Self Bias in CCP Deposition Systems
NASA Astrophysics Data System (ADS)
Keil, D. L.; Augustyniak, E.; Sakiyama, Y.
2013-09-01
In many commercial CCP plasma process systems the DC-self bias is available as a reported process parameter. Since commercial systems typically limit the number of onboard diagnostics, there is great incentive to understand how DC-self bias can be expected to respond to various system perturbations. This work reviews and examines DC self bias changes in response to tool aging, chamber film accumulation and wafer processing. The diagnostic value of the DC self bias response to transient and various steady state current draw schemes are examined. Theoretical models and measured experimental results are compared and contrasted.
Research on DC Micro-grid system of photovoltaic power generation
NASA Astrophysics Data System (ADS)
Zheng, Yiming; Wang, Xiaohui
2018-01-01
The use of energy has become a topic of concern, the demand of people for power grows in number or quantity with the development of economy. It is necessary to consider using new forms of power supply-microgrid system for distributed power supply. The power supply mode can not only effectively solve the problem of excessive line loss in the large power grid, but also can increase the reliability of the power supply, and is economical and environmental friendly. With the increasing of DC loads, in order to improve the utilization efficiency, the DC microgrid power supply problems are begin to be researched and integrated with the renewable energy sources. This paper researched the development of microgrid, compared AC microgrid with DC microgrid, summarized the distribution of DC bus voltage level, the DC microgrid network form, the control mode and the main power electronics elements of DC microgrid of photovoltaic power generation system. Today, the DC microgrid system is still in the development stage without uniform voltage level standard, however, it will come into service in the future.
NASA Technical Reports Server (NTRS)
Bahler, D. D.
1978-01-01
Procedures are presented for obtaining valid frequency-domain transfer functions of regulated reactor energy-storage dc-to-dc converters. These procedures are for measuring loop gain, closed loop gain, output impedance, and audio susceptibility. The applications of these measurements are discussed.
ERIC Educational Resources Information Center
Library Journal, 2010
2010-01-01
As host to visitors and transplants from around the world, Washington, DC, benefits from the constant infusion of different cultures. Although most neighborhoods lack a unified culinary flavor, make no mistake: DC is a city of distinctive areas, each with its own style, ensuring that hungry American Library Association (ALA) 2010 conference…
Development of toroid-type HTS DC reactor series for HVDC system
NASA Astrophysics Data System (ADS)
Kim, Kwangmin; Go, Byeong-Soo; Park, Hea-chul; Kim, Sung-kyu; Kim, Seokho; Lee, Sangjin; Oh, Yunsang; Park, Minwon; Yu, In-Keun
2015-11-01
This paper describes design specifications and performance of a toroid-type high-temperature superconducting (HTS) DC reactor. The first phase operation targets of the HTS DC reactor were 400 mH and 400 A. The authors have developed a real HTS DC reactor system during the last three years. The HTS DC reactor was designed using 2G GdBCO HTS wires. The HTS coils of the toroid-type DC reactor magnet were made in the form of a D-shape. The electromagnetic performance of the toroid-type HTS DC reactor magnet was analyzed using the finite element method program. A conduction cooling method was adopted for reactor magnet cooling. The total system has been successfully developed and tested in connection with LCC type HVDC system. Now, the authors are studying a 400 mH, kA class toroid-type HTS DC reactor for the next phase research. The 1500 A class DC reactor system was designed using layered 13 mm GdBCO 2G HTS wire. The expected operating temperature is under 30 K. These fundamental data obtained through both works will usefully be applied to design a real toroid-type HTS DC reactor for grid application.
Design of piezoelectric transformer for DC/DC converter with stochastic optimization method
NASA Astrophysics Data System (ADS)
Vasic, Dejan; Vido, Lionel
2016-04-01
Piezoelectric transformers were adopted in recent year due to their many inherent advantages such as safety, no EMI problem, low housing profile, and high power density, etc. The characteristics of the piezoelectric transformers are well known when the load impedance is a pure resistor. However, when piezoelectric transformers are used in AC/DC or DC/DC converters, there are non-linear electronic circuits connected before and after the transformer. Consequently, the output load is variable and due to the output capacitance of the transformer the optimal working point change. This paper starts from modeling a piezoelectric transformer connected to a full wave rectifier in order to discuss the design constraints and configuration of the transformer. The optimization method adopted here use the MOPSO algorithm (Multiple Objective Particle Swarm Optimization). We start with the formulation of the objective function and constraints; then the results give different sizes of the transformer and the characteristics. In other word, this method is looking for a best size of the transformer for optimal efficiency condition that is suitable for variable load. Furthermore, the size and the efficiency are found to be a trade-off. This paper proposes the completed design procedure to find the minimum size of PT in need. The completed design procedure is discussed by a given specification. The PT derived from the proposed design procedure can guarantee both good efficiency and enough range for load variation.
21 CFR 82.1104 - D&C Blue No. 4.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Blue No. 4. 82.1104 Section 82.1104 Food and... PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1104 D&C Blue No. 4. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74.1104(a)(1...
21 CFR 82.1104 - D&C Blue No. 4.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 1 2012-04-01 2012-04-01 false D&C Blue No. 4. 82.1104 Section 82.1104 Food and... PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1104 D&C Blue No. 4. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74.1104(a)(1...
21 CFR 74.2104 - D&C Blue No. 4.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 1 2013-04-01 2013-04-01 false D&C Blue No. 4. 74.2104 Section 74.2104 Food and... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2104 D&C Blue No. 4. (a) Identity and specifications. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74...
21 CFR 82.1104 - D&C Blue No. 4.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false D&C Blue No. 4. 82.1104 Section 82.1104 Food and... PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1104 D&C Blue No. 4. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74.1104(a)(1...
21 CFR 82.1104 - D&C Blue No. 4.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Blue No. 4. 82.1104 Section 82.1104 Food and... PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1104 D&C Blue No. 4. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74.1104(a)(1...
21 CFR 74.2104 - D&C Blue No. 4.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false D&C Blue No. 4. 74.2104 Section 74.2104 Food and... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2104 D&C Blue No. 4. (a) Identity and specifications. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74...
21 CFR 82.1104 - D&C Blue No. 4.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 1 2013-04-01 2013-04-01 false D&C Blue No. 4. 82.1104 Section 82.1104 Food and... PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1104 D&C Blue No. 4. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74.1104(a)(1...
21 CFR 74.2104 - D&C Blue No. 4.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 1 2012-04-01 2012-04-01 false D&C Blue No. 4. 74.2104 Section 74.2104 Food and... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2104 D&C Blue No. 4. (a) Identity and specifications. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74...
21 CFR 74.1336 - D&C Red No. 36.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 36. 74.1336 Section 74.1336 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1336 D&C Red No. 36. (a) Identity. (1) The color additive D&C...
21 CFR 74.1328 - D&C Red No. 28.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 28. 74.1328 Section 74.1328 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1328 D&C Red No. 28. (a) Identity. (1) The color additive D&C...
21 CFR 74.1339 - D&C Red No. 39.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 39. 74.1339 Section 74.1339 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1339 D&C Red No. 39. (a) Identity. (1) The color additive D&C...
21 CFR 74.1327 - D&C Red No. 27.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 27. 74.1327 Section 74.1327 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1327 D&C Red No. 27. (a) Identity. (1) The color additive D&C...
21 CFR 74.1317 - D&C Red No. 17.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 17. 74.1317 Section 74.1317 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1317 D&C Red No. 17. (a) Identity. (1) The color additive D&C...
21 CFR 74.1322 - D&C Red No. 22.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 22. 74.1322 Section 74.1322 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1322 D&C Red No. 22. (a) Identity. (1) The color additive D&C...
21 CFR 74.1331 - D&C Red No. 31.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 31. 74.1331 Section 74.1331 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1331 D&C Red No. 31. (a) Identity. (1) The color additive D&C...
21 CFR 74.1321 - D&C Red No. 21.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 21. 74.1321 Section 74.1321 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1321 D&C Red No. 21. (a) Identity. (1) The color additive D&C...
21 CFR 74.1208 - D&C Green No. 8.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Green No. 8. 74.1208 Section 74.1208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1208 D&C Green No. 8. (a) Identity. (1) The color additive D&C...
21 CFR 74.1205 - D&C Green No. 5.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false D&C Green No. 5. 74.1205 Section 74.1205 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1205 D&C Green No. 5. (a) Identity. (1) The color additive D&C...
21 CFR 74.1205 - D&C Green No. 5.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 1 2012-04-01 2012-04-01 false D&C Green No. 5. 74.1205 Section 74.1205 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1205 D&C Green No. 5. (a) Identity. (1) The color additive D&C...
21 CFR 74.1205 - D&C Green No. 5.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 1 2013-04-01 2013-04-01 false D&C Green No. 5. 74.1205 Section 74.1205 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1205 D&C Green No. 5. (a) Identity. (1) The color additive D&C...
21 CFR 74.1255 - D&C Orange No. 5.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 5. 74.1255 Section 74.1255 Food and... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1255 D&C Orange No. 5. (a) Identity. (1) the color additive D&C Orange No. 5 is a mixture consisting principally the sodium salt of 4′,5′-dibromofluorescein (CAS...
21 CFR 74.1261 - D&C Orange No. 11.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 11. 74.1261 Section 74.1261 Food... COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1261 D&C Orange No. 11. (a) Identity. (1) The color additive D&C Orange No. 11 is a mixture consisting principally of the disodium salts of 4′,5...
21 CFR 74.1254 - D&C Orange No. 4.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 4. 74.1254 Section 74.1254 Food and... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1254 D&C Orange No. 4. (a) Identity. (1) the color additive D&C Orange No. 4 is principally the sodium salt of 4-[(2-hydroxy-1-naphthalenyl)azo]benzenesulfonic...
21 CFR 82.1254 - D&C Orange No. 4.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 4. 82.1254 Section 82.1254 Food and... PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Drugs and Cosmetics § 82.1254 D&C Orange No. 4. The color additive D&C Orange No. 4 shall conform in identity and specifications to the requirements of § 74.1254(a...
Performance of a spacecraft DC-DC converter breadboard modified for low temperature operation
NASA Technical Reports Server (NTRS)
Gerber, Scott S.; Stell, Chris; Patterson, Richard; Ray, Biswajit
1996-01-01
A 1OW 3OV/5.OV push-pull dc-dc converter breadboard, designed by the Jet Propulsion Laboratory (JPL) with a +50 C to +5 C operating range for the Cassini space probe, was characterized for lower operating temperatures. The breadboard converter which failed to operate for temperatures below -125 C was then modified to operate at temperatures approaching that of liquid nitrogen (LN2). Associated with this low operating temperature range (greater than -196 C) was a variety of performance problems such as significant change in output voltage, converter switching instability, and failure to restart at temperatures below -154 C. An investigation into these problems yielded additional modifications to the converter which improved low temperature performance even further.
Comparison of control structures for a bidirectional high-frequency dc-dc converter
NASA Astrophysics Data System (ADS)
Himmelstoss, Felix A.; Kolar, Johann W.; Zach, Franz C.
1989-08-01
A system for dc-dc power conversion based on a buck-boost converter topology is presented. It makes power flow in both directions possible. The possibility of bidirectional power flow is useful for certain applications, such as uninterruptable power supplies. Starting from a structural diagram the transfer function of the system is derived. The controller for the converter is then designed. It is made up of a simple voltage controller, a voltage controller with an inner loop current controller (cascade control) and with two kinds of state space control. The transfer functions of the different system parts are derived and dimensioning guidelines for the controller sections are presented. The closed loop behavior of the bidirectional converter for the different control structures is analyzed based on simulation using duty cycle averaging. Bodediagrams and step responses are shown.
2. Basement tunnel plan: Pine (Building 6, HABS DC349AA), Linden ...
2. Basement tunnel plan: Pine (Building 6, HABS DC-349-AA), Linden (Building 28 HABS DC-349-AD), Holly (Building 29, HABS DC-349-AE), East Lodge / Detached Nurses Home (Building 30, HABS DC-349-AB) - St. Elizabeths Hospital, Tunnels, 2700 Martin Luther King Jr. Avenue, Southeast, Washington, District of Columbia, DC
21 CFR 74.1208 - D&C Green No. 8.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Green No. 8. 74.1208 Section 74.1208 Food and... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1208 D&C Green No. 8. (a) Identity. (1) The color additive D&C Green No. 8 is principally the trisodium salt of 8-hydroxy-1,3,6-pyrene-trisulfonic acid. (2) Color...
21 CFR 74.1104 - D&C Blue No. 4.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false D&C Blue No. 4. 74.1104 Section 74.1104 Food and... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1104 D&C Blue No. 4. (a) Identity. (1) The color additive D&C Blue No. 4 is principally the diammonium salt of ethyl[4-[p[ethyl(m- sulfobenzyl)ami-no]-α-(o...
21 CFR 74.1260 - D&C Orange No. 10.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 10. 74.1260 Section 74.1260 Food... COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1260 D&C Orange No. 10. (a) Identity. (1) The color additive D&C Orange No. 10 is a mixture consisting principally of 4′,5′-diiodofluorescein, 2′,4′,5...
Simulation of the dc Plasma in Carbon Nanotube Growth
NASA Technical Reports Server (NTRS)
Hash, David; Bose, Deepak; Govindan, T. R.; Meyyappan, M.; Biegel, Bryan (Technical Monitor)
2003-01-01
A model for the dc plasma used in carbon nanotube growth is presented, and one-dimensional simulations of an acetylene/ammonia/argon system are performed. The effect of dc bias is illustrated by examining electron temperature, electron and ion densities, and neutral densities. Introducing a tungsten filament in the dc plasma, as in hot filament chemical vapor deposition with plasma assistance, shows negligible influence on the system characteristics.
Sliding mode controller with modified sliding function for DC-DC Buck Converter.
Naik, B B; Mehta, A J
2017-09-01
This article presents design of Sliding Mode Controller with proportional integral type sliding function for DC-DC Buck Converter for the controlled power supply. The converter with conventional sliding mode controller results in a steady state error in load voltage. The proposed modified sliding function improves the steady state and dynamic performance of the Convertor and facilitates better choices of controller tuning parameters. The conditions for existence of sliding modes for proposed control scheme are derived. The stability of the closed loop system with proposed sliding mode control is proved and improvement in steady state performance is exemplified. The idea of adaptive tuning for the proposed controller to compensate load variations is outlined. The comparative study of conventional and proposed control strategy is presented. The efficacy of the proposed strategy is endowed by the simulation and experimental results. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.
Analysis of Discontinuity Induced Bifurcations in a Dual Input DC-DC Converter
NASA Astrophysics Data System (ADS)
Giaouris, Damian; Banerjee, Soumitro; Mandal, Kuntal; Al-Hindawi, Mohammed M.; Abusorrah, Abdullah; Al-Turki, Yusuf; El Aroudi, Abdelali
DC-DC power converters with multiple inputs and a single output are used in numerous applications where multiple sources, e.g. two or more renewable energy sources and/or a battery, feed a single load. In this work, a classical boost converter topology with two input branches connected to two different sources is chosen, with each branch independently being controlled by a separate peak current mode controller. We demonstrate for the first time that even though this converter is similar to other well known topologies that have been studied before, it exhibits many complex nonlinear behaviors that are not found in any other standard PWM controlled power converter. The system undergoes period incrementing cascade as a parameter is varied, with discontinuous hard transitions between consecutive periodicities. We show that the system can be described by a discontinuous map, which explains the observed bifurcation phenomena. The results have been experimentally validated.
Solar fed DC-DC single ended primary inductance converter for low power applications
NASA Astrophysics Data System (ADS)
Narendranath, K. V.; Viswanath, Y.; Babu, K. Suresh; Arunkumar, G.; Elangovan, D.
2017-11-01
This paper presents 34 to 36 volts. SEPIC converter for solar fed applications. Now days, there has been tremendous increase in the usage of solar energy and this solar energy is most valuable energy source available all around the world. The solar energy system require a Dc-Dc converter in order to modulate and govern the changing output of the panel. In this paper, a system comprising of Single Ended Primary Inductance Converter [SEPIC] integrated with solar panel is proposed. This paper proposes SEPIC power converter design that will secure high performance and cost efficiency while powering up a LAMP load. This power converter designed with low output ripple voltage, higher efficiency and less electrical pressure on the power switching elements. The simulation and prototype hardware results are presented in this paper.
Emulating DC constant power load: a robust sliding mode control approach
NASA Astrophysics Data System (ADS)
Singh, Suresh; Fulwani, Deepak; Kumar, Vinod
2017-09-01
This article presents emulation of a programmable power electronic, constant power load (CPL) using a dc/dc step-up (boost) converter. The converter is controlled by a robust sliding mode controller (SMC). A novel switching surface is proposed to ensure a required power sunk by the converter. The proposed dc CPL is simple in design, has fast dynamic response and high accuracy, and offers an inexpensive alternative to study converters for cascaded dc distribution power system applications. Furthermore, the proposed CPL is sufficiently robust against the input voltage variations. A laboratory prototype of the proposed dc CPL has been developed and validated with SMC realised through OPAL-RT platform. The capability of the proposed dc CPL is confirmed via experimentations in varied scenarios.
DC magnetic fields from the human body generally: a historical overview.
Cohen, D
2004-11-30
A review is presented of the earliest dc magnetic field (dcMF) measurements, made between 1969 and 1983, due to natural currents in the body. The measurements were essentially a mapping over the whole body, except for the brain (dcMEG), which was omitted because of interfering non-neural sources in the head. This mapping can be useful today in interpreting new measurements over the body, especially dcMEG data, where the new authors assume only a neural source in the head; our mapping suggests that this assumption may be in error. Briefly, in our mapping, dcMFs were found over almost the entire body; they were larger over the limbs and head than over the torso proper except over the abdomen, where it was usually the largest in the body Some of the sources were: 1. A strong and complicated reflex in the abdomen due to drinking cold water, suggesting that other dcMF reflexes might be common in the body. 2. Long muscle fibers in the limbs, suggesting sources also in scalp muscles. 3. Hair follicles due to touching the scalp; these sources could also exist, unrecognized, in recent dcMEG whole-head measurements. 4. Injury currents from the ischemic human heart, suggesting dcMFs could arise from injured muscle in the body generally. One major mechanism for producing dcMFs appeared to be a change in the potassium ion concentration in the vicinity of long excitable fibers. Overall, we concluded that the dcMFs were complicated, and it may be difficult to identify each source, especially in the head.
Implementation method of multi-terminal DC control system
NASA Astrophysics Data System (ADS)
Yi, Liu; Hao-Ran, Huang; Jun-Wen, Zhou; Hong-Guang, Guo; Yu-Yong, Zhou
2018-04-01
Currently the multi-terminal DC system (MTDC) has more stations. Each station needs operators to monitor and control the device. It needs much more operation and maintenance, low efficiency and small reliability; for the most important reason, multi-terminal DC system has complex control mode. If one of the stations has some problem, the control of the whole system should have problems. According to research of the characteristics of multi-terminal DC (VSC-MTDC) systems, this paper presents a strong implementation of the multi-terminal DC Supervisory Control and Data Acquisition (SCADA) system. This system is intelligent, can be networking, integration and intelligent. A master control system is added in each station to communication with the other stations to send current and DC voltage value to pole control system for each station. Based on the practical application and information feedback in the China South Power Grid research center VSC-MTDC project, this system is higher efficiency and save the cost on the maintenance of convertor station to improve the intelligent level and comprehensive effect. And because of the master control system, a multi-terminal system hierarchy coordination control strategy is formed, this make the control and protection system more efficiency and reliability.
Characteristics of DC electric fields in transient plasma sheet events
NASA Astrophysics Data System (ADS)
Laakso, H. E.; Escoubet, C. P.; Masson, A.
2015-12-01
We take an advantage of five different DC electric field measurements in the plasma sheet available from the EFW double probe experiment, EDI electron drift instrument, CODIF and HIA ion spectrometers, and PEACE electron spectrometer on the four Cluster spacecraft. The calibrated observations of the three spectrometers are used to determine the proton and electron velocity moments. The velocity moments can be used to estimate the proton and electron drift velocity and furthermore the DC electric field, assuming that the electron and proton velocity perpendicular to the magnetic field is dominated by the ExB drift motion. Naturally when ions and electrons do not perform a proper drift motion, which can happen in the plasma sheet, the estimated DC electric field from ion and electron motion is not correct. However, surprisingly often the DC electric fields estimated from electron and ion motions are identical suggesting that this field is a real DC electric field around the measurement point. As the measurement techniques are so different, it is quite plausible that when two different measurements yield the same DC electric field, it is the correct field. All five measurements of the DC electric field are usually not simultaneously available, especially on Cluster 2 where CODIF and HIA are not operational, or on Cluster 4 where EDI is off. In this presentation we investigate DC electric field in various transient plasma sheet events such as dipolarization events and BBF's and how the five measurements agree or disagree. There are plenty of important issues that are considered, e.g., (1) what kind of DC electric fields exist in such events and what are their spatial scales, (2) do electrons and ions perform ExB drift motions in these events, and (3) how well the instruments have been calibrated.
DC-8 MTP calibration for SOLVE-2
NASA Technical Reports Server (NTRS)
Mahoney, M. J.
2003-01-01
The Jet Propulsion Laboratory (JPL) Microwave Temperature Profiler (MTP) was the only instrument making temperature measurements at and below flight level on the DC-8 during the SOLVE-2 campaign. Many years of careful comparison of MTP measurements with radiosondes near the DC-8 flight track have shown that the flight level temperature can be determined to an accuracy of 0.2K relative to radiosondes.
pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation
Duraes, Fernanda V.; Lippens, Carla; Steinbach, Karin; Dubrot, Juan; Brighouse, Dale; Bendriss-Vermare, Nathalie; Issazadeh-Navikas, Shohreh; Merkler, Doron; Hugues, Stephanie
2016-01-01
Plasmacytoid dendritic cells (pDCs) exhibit both innate and adaptive functions. In particular they are the main source of type I IFNs and directly impact T cell responses through antigen presentation. We have previously demonstrated that during experimental autoimmune encephalomyelitis (EAE) initiation, myelin-antigen presentation by pDCs is associated with suppressive Treg development and results in attenuated EAE. Here, we show that pDCs transferred during acute disease phase confer recovery from EAE. Clinical improvement is associated with migration of injected pDCs into inflamed CNS and is dependent on the subsequent and selective chemerin-mediated recruitment of endogenous pDCs to the CNS. The protective effect requires pDC pre-loading with myelin antigen, and is associated with the modulation of CNS-infiltrating pDC phenotype and inhibition of CNS encephalitogenic T cells. This study may pave the way for novel pDC-based cell therapies in autoimmune diseases, aiming at specifically modulating pathogenic cells that induce and sustain autoimmune inflammation. PMID:26341385
Simulation Analysis of DC and Switching Impulse Superposition Circuit
NASA Astrophysics Data System (ADS)
Zhang, Chenmeng; Xie, Shijun; Zhang, Yu; Mao, Yuxiang
2018-03-01
Surge capacitors running between the natural bus and the ground are affected by DC and impulse superposition voltage during operation in the converter station. This paper analyses the simulation aging circuit of surge capacitors by PSCAD electromagnetic transient simulation software. This paper also analyses the effect of the DC voltage to the waveform of the impulse voltage generation. The effect of coupling capacitor to the test voltage waveform is also studied. Testing results prove that the DC voltage has little effect on the waveform of the output of the surge voltage generator, and the value of the coupling capacitor has little effect on the voltage waveform of the sample. Simulation results show that surge capacitor DC and impulse superimposed aging test is feasible.
Type I interferon regulates pDC maturation and Ly49Q expression.
Toma-Hirano, Makiko; Namiki, Sahori; Miyatake, Shoichiro; Arai, Ken-Ichi; Kamogawa-Schifter, Yumiko
2007-10-01
Ly49Q is expressed on peripheral mouse plasmacytoid dendritic cells (pDC). Immature Ly49Q-negative pDC precursors acquire Ly49Q in the bone marrow and then migrate into the periphery. While searching for molecules that regulate pDC maturation, we found that type I interferon (IFN) inhibited Ly49Q acquisition in vitro. Infections that induce type I IFN production by cells other than pDC (a condition mimicked by poly(I:C) injection in vivo) increase the prevalence of Ly49Q(-) pDC in the bone marrow and peripheral lymphoid organs in wild-type but not IFN-alpha/beta receptor knockout BALB/c mice. Moreover, in vivo exposure to type I IFN causes some Ly49Q(-), but not Ly49Q(+), pDC to convert to conventional DC, defined as B220(-) CD11c(+) CD11b(+) cells. These data suggest that type I IFN regulates pDC development and affects their distribution in the body.
Determination of appropriate DC voltage for switched mode power supply (SMPS) loads
NASA Astrophysics Data System (ADS)
Setiawan, Eko Adhi; Setiawan, Aiman; Purnomo, Andri; Djamal, Muchlishah Hadi
2017-03-01
Nowadays, most of modern and efficient household electronic devices operated based on Switched Mode Power Supply (SMPS) technology which convert AC voltage from the grid to DC voltage. Based on theory and experiment, SMPS loads could be supplied by DC voltage. However, the DC voltage rating to energize electronic home appliances is not standardized yet. This paper proposed certain method to determine appropriate DC voltage, and investigated comparison of SMPS power consumption which is supplied from AC and DC voltage. To determine the appropriate DC voltage, lux value of several lamps which have same specification energized by using AC voltage and the results is using as reference. Then, the lamps were supplied by various DC voltage to obtain the trends of the lux value to the applied DC voltage. After that, by using the trends and the reference lux value, the appropriate DC voltage can be determined. Furthermore, the power consumption on home appliances such as mobile phone, laptop and personal computer by using AC voltage and the appropriate DC voltage were conducted. The results show that the total power consumption of AC system is higher than DC system. The total power (apparent power) consumed by the lamp, mobile phone and personal computer which operated in 220 VAC were 6.93 VA, 34.31 VA and 105.85 VA respectively. On the other hand, under 277 VDC the load consumption were 5.83 W, 19.11 W and 74.46 W respectively.
Optimal Power Scheduling for a Medium Voltage AC/DC Hybrid Distribution Network
Zhu, Zhenshan; Liu, Dichen; Liao, Qingfen; ...
2018-01-26
With the great increase of renewable generation as well as the DC loads in the distribution network; DC distribution technology is receiving more attention; since the DC distribution network can improve operating efficiency and power quality by reducing the energy conversion stages. This paper presents a new architecture for the medium voltage AC/DC hybrid distribution network; where the AC and DC subgrids are looped by normally closed AC soft open point (ACSOP) and DC soft open point (DCSOP); respectively. The proposed AC/DC hybrid distribution systems contain renewable generation (i.e., wind power and photovoltaic (PV) generation); energy storage systems (ESSs); softmore » open points (SOPs); and both AC and DC flexible demands. An energy management strategy for the hybrid system is presented based on the dynamic optimal power flow (DOPF) method. The main objective of the proposed power scheduling strategy is to minimize the operating cost and reduce the curtailment of renewable generation while meeting operational and technical constraints. The proposed approach is verified in five scenarios. The five scenarios are classified as pure AC system; hybrid AC/DC system; hybrid system with interlinking converter; hybrid system with DC flexible demand; and hybrid system with SOPs. Results show that the proposed scheduling method can successfully dispatch the controllable elements; and that the presented architecture for the AC/DC hybrid distribution system is beneficial for reducing operating cost and renewable generation curtailment.« less
Optimal Power Scheduling for a Medium Voltage AC/DC Hybrid Distribution Network
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhu, Zhenshan; Liu, Dichen; Liao, Qingfen
With the great increase of renewable generation as well as the DC loads in the distribution network; DC distribution technology is receiving more attention; since the DC distribution network can improve operating efficiency and power quality by reducing the energy conversion stages. This paper presents a new architecture for the medium voltage AC/DC hybrid distribution network; where the AC and DC subgrids are looped by normally closed AC soft open point (ACSOP) and DC soft open point (DCSOP); respectively. The proposed AC/DC hybrid distribution systems contain renewable generation (i.e., wind power and photovoltaic (PV) generation); energy storage systems (ESSs); softmore » open points (SOPs); and both AC and DC flexible demands. An energy management strategy for the hybrid system is presented based on the dynamic optimal power flow (DOPF) method. The main objective of the proposed power scheduling strategy is to minimize the operating cost and reduce the curtailment of renewable generation while meeting operational and technical constraints. The proposed approach is verified in five scenarios. The five scenarios are classified as pure AC system; hybrid AC/DC system; hybrid system with interlinking converter; hybrid system with DC flexible demand; and hybrid system with SOPs. Results show that the proposed scheduling method can successfully dispatch the controllable elements; and that the presented architecture for the AC/DC hybrid distribution system is beneficial for reducing operating cost and renewable generation curtailment.« less
An Optimal Current Observer for Predictive Current Controlled Buck DC-DC Converters
Min, Run; Chen, Chen; Zhang, Xiaodong; Zou, Xuecheng; Tong, Qiaoling; Zhang, Qiao
2014-01-01
In digital current mode controlled DC-DC converters, conventional current sensors might not provide isolation at a minimized price, power loss and size. Therefore, a current observer which can be realized based on the digital circuit itself, is a possible substitute. However, the observed current may diverge due to the parasitic resistors and the forward conduction voltage of the diode. Moreover, the divergence of the observed current will cause steady state errors in the output voltage. In this paper, an optimal current observer is proposed. It achieves the highest observation accuracy by compensating for all the known parasitic parameters. By employing the optimal current observer-based predictive current controller, a buck converter is implemented. The converter has a convergently and accurately observed inductor current, and shows preferable transient response than the conventional voltage mode controlled converter. Besides, costs, power loss and size are minimized since the strategy requires no additional hardware for current sensing. The effectiveness of the proposed optimal current observer is demonstrated experimentally. PMID:24854061
Yu, Xiudao; Killiny, Nabil
2018-03-01
The Asian citrus psyllid, Diaphorina citri Kuwayama, is an important agricultural pest of citrus globally. Foliar application of chemical insecticides is the most widely used option for reducing D. citri populations. Knockdown of glutathione S-transferase (GST) in several insect species leads to increased susceptibility to insecticides; however, information about the detoxifying role of GST genes in D. citri is unavailable. Via a sequence homology search, we isolated and characterized three DcGST genes (DcGSTd1, DcGSTe1 and DcGSTe2) from D. citri. Phylogenetic analysis grouped DcGSTd1 into the delta class of GST genes, whereas DcGSTe1 and DcGSTe2 were clustered in the epsilon clade. Gene expression analysis revealed that chlorpyrifos treatment increased the mRNA levels of DcGSTe1 and fenpropathrin enhanced the expression level of DcGSTd1, while DcGSTe2 was significantly up-regulated after exposure to thiamethoxam at a dose of 30% lethal concentration (LC30). RNA interference (RNAi) of DcGSTe2 and DcGSTd1 followed by an insecticide bioassay increased the mortalities of thiamethoxam-treated psyllids by 23.0% and fenpropathrin-treated psyllids by 15.0%. In contrast, knockdown of DcGSTe1 did not significantly increase the susceptibility of D. citri to any of these three insecticides. Further, feeding with double-stranded RNA (dsDcGSTe2-d1) interfusion co-silenced DcGSTe2 and DcGSTd1 expression in D. citri, and led to an increase of susceptibility to both fenpropathrin and thiamethoxam. The findings suggest that DcGSTe2 and DcGSTd1 play unique roles in detoxification of the pesticides thiamethoxam and fenpropathrin. In addition, co-silencing by creating a well-designed dsRNA interfusion against multiple genes was a good RNAi strategy in D. citri. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.
Analysis of Electric Vehicle DC High Current Conversion Technology
NASA Astrophysics Data System (ADS)
Yang, Jing; Bai, Jing-fen; Lin, Fan-tao; Lu, Da
2017-05-01
Based on the background of electric vehicles, it is elaborated the necessity about electric energy accurate metering of electric vehicle power batteries, and it is analyzed about the charging and discharging characteristics of power batteries. It is needed a DC large current converter to realize accurate calibration of power batteries electric energy metering. Several kinds of measuring methods are analyzed based on shunts and magnetic induction principle in detail. It is put forward power batteries charge and discharge calibration system principle, and it is simulated and analyzed ripple waves containing rate and harmonic waves containing rate of power batteries AC side and DC side. It is put forward suitable DC large current measurement methods of power batteries by comparing different measurement principles and it is looked forward the DC large current measurement techniques.
Evaluation of the Washington, D.C. Parking Enforcement Program
DOT National Transportation Integrated Search
1982-09-01
This report documents the evaluation of the Washington, DC, parking enforcement program. This comprehensive program is operated by the District of Columbia, Department of Transportation (DC DOT). The program has resulted in the successful integration...
Photovoltaic system with improved DC connections and method of making same
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cioffi, Philip Michael; Todorovic, Maja Harfman; Herzog, Michael Scott
A micro-inverter assembly includes a housing having an opening formed in a bottom surface thereof, and a direct current (DC)-to-alternating current (AC) micro-inverter disposed within the housing at a position adjacent to the opening. The micro-inverter assembly further includes a micro-inverter DC connector electrically coupled to the DC-to-AC micro-inverter and positioned within the opening of the housing, the micro-inverter DC connector having a plurality of exposed electrical contacts.
The Market Response to the Sioux City DC-10 Crash.
Barnett, Arnold; Menighetti, John; Prete, Matthew
1992-03-01
The 1989 DC-10 crash at Sioux City, Iowa presented a rare instance in which a potential threat to safety was both (i) intensely publicized over a short period and (ii) also amenable to the unobtrusive measurement of the market reaction it evoked. As such, it allowed a useful case study of the extent and duration of behavior change caused by a frightening event. Using reservations data from travel agencies in five states, this paper estimates the short-term effects of the Sioux City crash on passenger willingness to fly the DC-10. The data suggest that, in the first few weeks after the crash, more than one third of travelers who would normally have booked DC-10 flights chose instead to fly other aircraft. Within 2 months of the disaster, however, DC-10 bookings rebounded to within 10% of the level that would have been expected had the Sioux City crash not occurred. At no time, apparently, did the airlines that operate DC-10s use their "yield-management" computer pricing systems unofficially to lower DC-10 fares relative to those on other types of plane.
Research on MMC-SST Oriented AC/DC Distribution System
NASA Astrophysics Data System (ADS)
Xie, Xifeng; Shi, Hua; Zuo, Jianglin; Zhang, Zhigang
2018-01-01
A modular multilevel converter-solid state transformer (MMC-SST) oriented AC/DC Distribution System is designed. Firstly, the topology structure is introduced, MMC is adopted in the input stage, multiple DC-DC converters are adopted in the isolation stage, and a Three-Phase Four-Leg inverter is adopted in the output stage. Then, the control strategy is analysed. Finally, simulation model and an experimental prototype of MMC-SST are built, simulation and experimental results show that topology and control strategy of MMC-SST are feasible.
Optimization of spin-torque switching using AC and DC pulses
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dunn, Tom; Kamenev, Alex; Fine Theoretical Physics Institute, University of Minnesota, Minneapolis, Minnesota 55455
2014-06-21
We explore spin-torque induced magnetic reversal in magnetic tunnel junctions using combined AC and DC spin-current pulses. We calculate the optimal pulse times and current strengths for both AC and DC pulses as well as the optimal AC signal frequency, needed to minimize the Joule heat lost during the switching process. The results of this optimization are compared against numeric simulations. Finally, we show how this optimization leads to different dynamic regimes, where switching is optimized by either a purely AC or DC spin-current, or a combination AC/DC spin-current, depending on the anisotropy energies and the spin-current polarization.
Radiofrequency amplifier based on a dc superconducting quantum interference device
Hilbert, C.; Martinis, J.M.; Clarke, J.
1984-04-27
A low noise radiofrequency amplifer, using a dc SQUID (superconducting quantum interference device) as the input amplifying element. The dc SQUID and an input coil are maintained at superconductivity temperatures in a superconducting shield, with the input coil inductively coupled to the superconducting ring of the dc SQUID. A radiofrequency signal from outside the shield is applied to the input coil, and an amplified radiofrequency signal is developed across the dc SQUID ring and transmitted to exteriorly of the shield. A power gain of 19.5 +- 0.5 dB has been achieved with a noise temperature of 1.0 +- 0.4 K at a frequency of 100 MHz.
Discharge Characteristic of VHF-DC Superimposed Magnetron Sputtering System
NASA Astrophysics Data System (ADS)
Toyoda, Hirotaka; Fukuoka, Yushi; Fukui, Takashi; Takada, Noriharu; Sasai, Kensuke
2014-10-01
Magnetron plasmas are one of the most important tools for sputter deposition of thin films. However, energetic particles from the sputtered target such as backscattered rare gas atoms or oxygen negative ions from oxide targets sometimes induce physical and chemical damages as well as surface roughening to the deposited film surface during the sputtering processes. To suppress kinetic energy of such particles, superposition of RF or VHF power to the DC power has been investigated. In this study, influence of the VHF power superposition on the DC target voltage, which is important factor to determine kinetic energy of high energy particles, is investigated. In the study, 40 MHz VHF power was superimposed to an ITO target and decrease in the target DC voltage was measured as well as deposited film deposition properties such as deposition rate or electrical conductivity. From systematic measurement of the target voltage, it was revealed that the target voltage can be determined by a very simple parameter, i.e., a ratio of VHF power to the total input power (DC and VHF powers) in spite of the DC discharge current. Part of this work was supported by ASTEP, JST.
Results of winglet development studies for DC-10 derivatives
NASA Technical Reports Server (NTRS)
Shollenberger, C. A.; Humphreys, J. W.; Heiberger, F. S.; Pearson, R. M.
1983-01-01
The results of investigations into the application of winglets to the DC-10 aircraft are presented. The DC-10 winglet configuration was developed and its cruise performance determined in a previous investigation. This study included high speed and low speed wind tunnel tests to evaluate aerodynamic characteristics, and a subsonic flutter wind tunnel test with accompanying analysis and evaluation of results. Additionally, a configuration integration study employed the results of the wind tunnel studies to determine the overall impact of the installation of winglets on the DC-10 aircraft. Conclusions derived from the high speed and low speed tests indicate that the winglets had no significant effects on the DC-10 stability characteristics or high speed buffet. It was determined that winglets had a minimal effect on aircraft lift characteristics and improved the low speed aircraft drag under high lift conditions. The winglets affected the DC-10 flutter characteristics by reducing the flutter speed of the basic critical mode and introducing a new critical mode involving outer wing torsion and longitudinal bending. The overall impact of winglets was determined to be of sufficient benefit to merit flight evaluation.
Mathematical model for the dc-ac inverter for the Space Shuttle
NASA Technical Reports Server (NTRS)
Berry, Frederick C.
1987-01-01
The reader is informed of what was done for the mathematical modeling of the dc-ac inverter for the Space Shuttle. The mathematical modeling of the dc-ac inverter is an essential element in the modeling of the electrical power distribution system of the Space Shuttle. The electrical power distribution system which is present on the Space Shuttle is made up to 3 strings each having a fuel cell which provides dc to those systems which require dc, and the inverters which convert the dc to ac for those elements which require ac. The inverters are units which are 2 wire structures for the main dc inputs and 2 wire structures for the ac output. When 3 are connected together a 4 wire wye connection results on the ac side. The method of modeling is performed by using a Least Squares curve fitting method. A computer program is presented for implementation of the model along with graphs and tables to demonstrate the accuracy of the model.
Campiotti, Richard H.; Hopwood, James E.
1990-01-01
A system for starting an arc for welding uses three DC power supplies, a high voltage supply for initiating the arc, an intermediate voltage supply for sustaining the arc, and a low voltage welding supply directly connected across the gap after the high voltage supply is disconnected.
Human Milk Blocks DC-SIGN–Pathogen Interaction via MUC1
Koning, Nathalie; Kessen, Sabine F. M.; Van Der Voorn, J. Patrick; Appelmelk, Ben J.; Jeurink, Prescilla V.; Knippels, Leon M. J.; Garssen, Johan; Van Kooyk, Yvette
2015-01-01
Beneficial effects of breastfeeding are well-recognized and include both immediate neonatal protection against pathogens and long-term protection against allergies and autoimmune diseases. Although several proteins have been identified to have anti-viral or anti-bacterial effects like secretory IgA or lactoferrin, the mechanisms of immune modulation are not fully understood. Recent studies identified important beneficial effects of glycans in human milk, such as those expressed in oligosaccharides or on glycoproteins. Glycans are recognized by the carbohydrate receptors C-type lectins on dendritic cell (DC) and specific tissue macrophages, which exert important functions in immune modulation and immune homeostasis. A well-characterized C-type lectin is dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), which binds terminal fucose. The present study shows that in human milk, MUC1 is the major milk glycoprotein that binds to the lectin domain of DC-SIGN and prevents pathogen interaction through the presence of Lewis x-type oligosaccharides. Surprisingly, this was specific for human milk, as formula, bovine or camel milk did not show any presence of proteins that interacted with DC-SIGN. The expression of DC-SIGN is found in young infants along the entire gastrointestinal tract. Our data thus suggest the importance of human milk glycoproteins for blocking pathogen interaction to DC in young children. Moreover, a potential benefit of human milk later in life in shaping the infants immune system through DC-SIGN cannot be ruled out. PMID:25821450
Greening America's Capitals - Washington, DC
This Greening America's Capitals report describes design options for the Anacostia Metro station in Washington, DC, that could help people feel safer and more comfortable walking to and from the station.
NASA Astrophysics Data System (ADS)
Jeffery, Rondo N.; Amiri, Farhang
2016-02-01
The classroom jumping ring demonstration is nearly always performed using alternating current (AC), in which the ring jumps or flies off the extended iron core when the switch is closed. The ring jumps higher when cooled with liquid nitrogen (LN2). We have performed experiments using DC to power the solenoid and find similarities and significant differences from the AC case. In particular, the ring does not fly off the core but rises a short distance and then falls back. If the ring jumps high enough, the rising and the falling motion of the ring does not follow simple vertical motion of a projectile. This indicates that there are additional forces on the ring in each part of its motion. Four possible stages of the motion of the ring with DC are identified, which result from the ring current changing directions during the jump in response to a changing magnetic flux through the moving ring.
Regulated dc-to-dc converter for voltage step-up or step-down with input-output isolation
NASA Technical Reports Server (NTRS)
Feng, S. Y.; Wilson, T. G. (Inventor)
1973-01-01
A closed loop regulated dc-to-dc converter employing an unregulated two winding inductive energy storage converter is provided by using a magnetically coupled multivibrator acting as duty cycle generator to drive the converter. The multivibrator is comprised of two transistor switches and a saturable transformer. The output of the converter is compared with a reference in a comparator which transmits a binary zero until the output exceeds the reference. When the output exceeds the reference, the binary output of the comparator drives transistor switches to turn the multivibrator off. The multivibrator is unbalanced so that a predetermined transistor will always turn on first when the binary feedback signal becomes zero.
DC-8 Airborne Laboratory in flight
1998-02-20
The NASA DC-8 in a right bank over the rugged Sierra Nevada Mountains. The former airliner is a "dash-72" model and has a range of 5,500 miles. The craft can stay airborne for 12 hours and has an operational speed range between 300 and 500 knots. The research flights are made at between 500 and 41,000 feet. The aircraft can carry up to 30,000 lbs of research/science payload equipment installed in 15 mission-definable spaces. In this photo, the aircraft is shown in flight from below, with the DC-8 silhouetted against a blue sky.
pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation.
Duraes, Fernanda V; Lippens, Carla; Steinbach, Karin; Dubrot, Juan; Brighouse, Dale; Bendriss-Vermare, Nathalie; Issazadeh-Navikas, Shohreh; Merkler, Doron; Hugues, Stephanie
2016-02-01
Plasmacytoid dendritic cells (pDCs) exhibit both innate and adaptive functions. In particular they are the main source of type I IFNs and directly impact T cell responses through antigen presentation. We have previously demonstrated that during experimental autoimmune encephalomyelitis (EAE) initiation, myelin-antigen presentation by pDCs is associated with suppressive Treg development and results in attenuated EAE. Here, we show that pDCs transferred during acute disease phase confer recovery from EAE. Clinical improvement is associated with migration of injected pDCs into inflamed CNS and is dependent on the subsequent and selective chemerin-mediated recruitment of endogenous pDCs to the CNS. The protective effect requires pDC pre-loading with myelin antigen, and is associated with the modulation of CNS-infiltrating pDC phenotype and inhibition of CNS encephalitogenic T cells. This study may pave the way for novel pDC-based cell therapies in autoimmune diseases, aiming at specifically modulating pathogenic cells that induce and sustain autoimmune inflammation. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
Read-out electronics for DC squid magnetic measurements
Ganther, Jr., Kenneth R.; Snapp, Lowell D.
2002-01-01
Read-out electronics for DC SQUID sensor systems, the read-out electronics incorporating low Johnson noise radio-frequency flux-locked loop circuitry and digital signal processing algorithms in order to improve upon the prior art by a factor of at least ten, thereby alleviating problems caused by magnetic interference when operating DC SQUID sensor systems in magnetically unshielded environments.
DC Microgrids Scoping Study. Estimate of Technical and Economic Benefits
DOE Office of Scientific and Technical Information (OSTI.GOV)
Backhaus, Scott N.; Swift, Gregory William; Chatzivasileiadis, Spyridon
Microgrid demonstrations and deployments are expanding in US power systems and around the world. Although goals are specific to each site, these microgrids have demonstrated the ability to provide higher reliability and higher power quality than utility power systems and improved energy utilization. The vast majority of these microgrids are based on AC power transfer because this has been the traditionally dominant power delivery scheme. Independently, manufacturers, power system designers and researchers are demonstrating and deploying DC power distribution systems for applications where the end-use loads are natively DC, e.g., computers, solid-state lighting, and building networks. These early DC applicationsmore » may provide higher efficiency, added flexibility, reduced capital costs over their AC counterparts. Further, when onsite renewable generation, electric vehicles and storage systems are present, DC-based microgrids may offer additional benefits. Early successes from these efforts raises a question - can a combination of microgrid concepts and DC distribution systems provide added benefits beyond what has been achieved individually?« less
Long-term trends in patron satisfaction of DC Circulator.
DOT National Transportation Integrated Search
2013-10-01
The DC Circulator is a local transit system designed to facilitate travel to and within the central business area in the District of Columbia. Since its inception in 2005, the Downtown DC Business Improvement District (DCBID) and the District Departm...
Variable Rail Voltage Control of a Brushless DC (BLDC) Motor
2013-01-01
Variable Rail Voltage Control of a Brushless DC ( BLDC ) Motor by Yuan Chen, Joseph Conroy, and William Nothwang ARL-TR-6308 January 2013...TR-6308 January 2013 Variable Rail Voltage Control of a Brushless DC ( BLDC ) Motor Yuan Chen, Joseph Conroy, and William Nothwang Sensors...DATES COVERED (From - To) 4. TITLE AND SUBTITLE Variable Rail Voltage Control of a Brushless DC ( BLDC ) Motor 5a. CONTRACT NUMBER 5b. GRANT
Post-Cure Studies on Solid Silicone Elastomer: DC745U
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ortiz-Acosta, Denisse; Janicke, Michael T.; Yoder, Jacob
DC745U is a silicone elastomer originally manufactured by Dow Corning under the name of Silastic® DC745U at their manufacturing facility in Kendaville, Indiana. Currently DC745U is available through Xiameter® or Dow Corning’s distributor R. D. Abbott Company. This silicone elastomer is used in numerous parts of weapon systems, including outer pressure pads, aft cap support in W80 and pressure pad in the B61. DC745U is a proprietary formulation and limited information about its composition and properties is provided to the customer. Thus, Los Alamos National Laboratory and Lawrence Livermore National Laboratory have performed a variety of characterization experiments on thismore » material.« less
Research on key technology of planning and design for AC/DC hybrid distribution network
NASA Astrophysics Data System (ADS)
Shen, Yu; Wu, Guilian; Zheng, Huan; Deng, Junpeng; Shi, Pengjia
2018-04-01
With the increasing demand of DC generation and DC load, the development of DC technology, AC and DC distribution network integrating will become an important form of future distribution network. In this paper, the key technology of planning and design for AC/DC hybrid distribution network is proposed, including the selection of AC and DC voltage series, the design of typical grid structure and the comprehensive evaluation method of planning scheme. The research results provide some ideas and directions for the future development of AC/DC hybrid distribution network.
Robust control of the DC-DC boost converter based on the uncertainty and disturbance estimator
NASA Astrophysics Data System (ADS)
Oucheriah, Said
2017-11-01
In this paper, a robust non-linear controller based on the uncertainty and disturbance estimator (UDE) scheme is successfully developed and implemented for the output voltage regulation of the DC-DC boost converter. System uncertainties, external disturbances and unknown non-linear dynamics are lumped as a signal that is accurately estimated using a low-pass filter and their effects are cancelled by the controller. This methodology forms the basis of the UDE-based controller. A simple procedure is also developed that systematically determines the parameters of the controller to meet certain specifications. Using simulation, the effectiveness of the proposed controller is compared against the sliding-mode control (SMC). Experimental tests also show that the proposed controller is robust to system uncertainties, large input and load perturbations.
NASA Technical Reports Server (NTRS)
Schoenfeld, A. D.; Yu, Y.
1973-01-01
Versatile standardized pulse modulation nondissipatively regulated control signal processing circuits were applied to three most commonly used dc to dc power converter configurations: (1) the series switching buck-regulator, (2) the pulse modulated parallel inverter, and (3) the buck-boost converter. The unique control concept and the commonality of control functions for all switching regulators have resulted in improved static and dynamic performance and control circuit standardization. New power-circuit technology was also applied to enhance reliability and to achieve optimum weight and efficiency.
Pulsed DC Electric Field–Induced Differentiation of Cortical Neural Precursor Cells
Chang, Hui-Fang; Lee, Ying-Shan; Tang, Tang K.; Cheng, Ji-Yen
2016-01-01
We report the differentiation of neural stem and progenitor cells solely induced by direct current (DC) pulses stimulation. Neural stem and progenitor cells in the adult mammalian brain are promising candidates for the development of therapeutic neuroregeneration strategies. The differentiation of neural stem and progenitor cells depends on various in vivo environmental factors, such as nerve growth factor and endogenous EF. In this study, we demonstrated that the morphologic and phenotypic changes of mouse neural stem and progenitor cells (mNPCs) could be induced solely by exposure to square-wave DC pulses (magnitude 300 mV/mm at frequency of 100-Hz). The DC pulse stimulation was conducted for 48 h, and the morphologic changes of mNPCs were monitored continuously. The length of primary processes and the amount of branching significantly increased after stimulation by DC pulses for 48 h. After DC pulse treatment, the mNPCs differentiated into neurons, astrocytes, and oligodendrocytes simultaneously in stem cell maintenance medium. Our results suggest that simple DC pulse treatment could control the fate of NPCs. With further studies, DC pulses may be applied to manipulate NPC differentiation and may be used for the development of therapeutic strategies that employ NPCs to treat nervous system disorders. PMID:27352251
Faraday-Shielded dc Stark-Shift-Free Optical Lattice Clock
NASA Astrophysics Data System (ADS)
Beloy, K.; Zhang, X.; McGrew, W. F.; Hinkley, N.; Yoon, T. H.; Nicolodi, D.; Fasano, R. J.; Schäffer, S. A.; Brown, R. C.; Ludlow, A. D.
2018-05-01
We demonstrate the absence of a dc Stark shift in an ytterbium optical lattice clock. Stray electric fields are suppressed through the introduction of an in-vacuum Faraday shield. Still, the effectiveness of the shielding must be experimentally assessed. Such diagnostics are accomplished by applying high voltage to six electrodes, which are grounded in normal operation to form part of the Faraday shield. Our measurements place a constraint on the dc Stark shift at the 10-20 level, in units of the clock frequency. Moreover, we discuss a potential source of error in strategies to precisely measure or cancel nonzero dc Stark shifts, attributed to field gradients coupled with the finite spatial extent of the lattice-trapped atoms. With this consideration, we find that Faraday shielding, complemented with experimental validation, provides both a practically appealing and effective solution to the problem of dc Stark shifts in optical lattice clocks.
Faraday-Shielded dc Stark-Shift-Free Optical Lattice Clock.
Beloy, K; Zhang, X; McGrew, W F; Hinkley, N; Yoon, T H; Nicolodi, D; Fasano, R J; Schäffer, S A; Brown, R C; Ludlow, A D
2018-05-04
We demonstrate the absence of a dc Stark shift in an ytterbium optical lattice clock. Stray electric fields are suppressed through the introduction of an in-vacuum Faraday shield. Still, the effectiveness of the shielding must be experimentally assessed. Such diagnostics are accomplished by applying high voltage to six electrodes, which are grounded in normal operation to form part of the Faraday shield. Our measurements place a constraint on the dc Stark shift at the 10^{-20} level, in units of the clock frequency. Moreover, we discuss a potential source of error in strategies to precisely measure or cancel nonzero dc Stark shifts, attributed to field gradients coupled with the finite spatial extent of the lattice-trapped atoms. With this consideration, we find that Faraday shielding, complemented with experimental validation, provides both a practically appealing and effective solution to the problem of dc Stark shifts in optical lattice clocks.
Power and Energy Management Strategy for Solid State Transformer Interfaced DC Microgrid
NASA Astrophysics Data System (ADS)
Yu, Xunwei
As a result of more and more applications of renewable energy into our ordinary life, how to construct a microgrid (MG) based on the distributed renewable energy resources and energy storages, and then to supply a reliable and flexible power to the conventional power system are the hottest topics nowadays. Comparing to the AC microgrid (AC MG), DC microgrid (DC MG) gets more attentions, because it has its own advantages, such as high efficiency, easy to integrate the DC energy sources and energy storages, and so on. Furthermore, the interaction between DC MG system and the distribution system is also an important and practical issue. In Future Renewable Electric Energy Delivery and Management Systems Center (FREEDM), the Solid State Transformer (SST) is built, which can transform the distribution system to the low AC and DC system directly (usually home application level). Thus, the SST gives a new promising solution for low voltage level MG to interface the distribution level system instead of the traditional transformer. So a SST interfaced DC MG is proposed. However, it also brings new challenges in the design and control fields for this system because the system gets more complicated, which includes distributed energy sources and storages, load, and SST. The purpose of this dissertation is to design a reliable and flexible SST interfaced DC MG based on the renewable energy sources and energy storages, which can operate in islanding mode and SST-enabled mode. Dual Half Bridge (DHB) is selected as the topology for DC/DC converter in DC MG. The DHB operation procedure and average model are analyzed, which is the basis for the system modeling, control and operation. Furthermore, two novel power and energy management strategies are proposed. The first one is a distributed energy management strategy for the DC MG operating in the SST-enabled mode. In this method, the system is not only in distributed control to increase the system reliability, but the power sharing
Ye, Qing
2013-06-01
In this work, microwave distillation assisted by Fe2 O3 magnetic microspheres (FMMS) and headspace single-drop microextraction were combined, and developed for determination of essential oil compounds in dried Zanthoxylum bungeanum Maxim (ZBM). The FMMS were used as microwave absorption solid medium for dry distillation of dried ZBM. Using the proposed method, isolation, extraction, and concentration of essential oil compounds can be carried out in a single step. The experimental parameters including extraction solvent, solvent volume, microwave power, irradiation time, and the amount of added FMMS, were studied. The optimal analytical conditions were: 2.0 μL decane as the extraction solvent, microwave power of 300 W, irradiation time of 2 min, and the addition of 0.1 g FMMS to ZBM. The method precision was from 4 to 10%. A total of 52 compounds were identified by the proposed method. The conventional steam distillation method was also used for the analysis of essential oil in dried ZBM and only 31 compounds were identified by steam distillation method. It was found that the proposed method is a simple, rapid, reliable, and solvent-free technique for the determination of volatile compounds in Chinese herbs. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
CSMP (Continuous System Modeling Program) Modeling of Brushless DC Motors.
1984-09-01
Characteristics of Fifteen HP Samarium Cobalt and Ferrite Based brushless DC Ictcrs j. Operated by the Same Power Conditioner ," IEEE Transactions on Pcwer stenM...paratus and Systeis, v. P -Ii-- -ry Demerdash, N.A. and Nehl.T.W., Dynamic Modeling cf Brushless DC Motor-Power Conditioner U if-- fo -- Iec tro me...III _J- _ o 0 NAVAL POSTGRADUATE SCHOOL Monterey, California •S THETIS CSMP MODEL{ING OF BRUSHLESS DC MOTORS by DTIC
Gas tube-switched high voltage DC power converter
She, Xu; Bray, James William; Sommerer, Timothy John; Chokhawala, Rahul
2018-05-15
A direct current (DC)-DC converter includes a transformer and a gas tube-switched inverter circuit. The transformer includes a primary winding and a secondary winding. The gas tube-switched inverter circuit includes first and second inverter load terminals and first and second inverter input terminals. The first and second inverter load terminals are coupled to the primary winding. The first and second inverter input terminals are couplable to a DC node. The gas tube-switched inverter circuit further includes a plurality of gas tube switches respectively coupled between the first and second inverter load terminals and the first and second inverter input terminals. The plurality of gas tube switches is configured to operate to generate an alternating current (AC) voltage at the primary winding.
4He sample probe for combined microwave and dc transport measurements
NASA Astrophysics Data System (ADS)
Dobrovolskiy, Oleksandr V.; Franke, Jörg; Huth, Michael
2015-03-01
Combined microwave and dc electrical transport measurements at low temperatures represent a valuable experimental method in many research areas. In particular, when samples are conventional superconductors, a typical experiment requires a combination of helium temperatures, a wide range of magnetic fields, and the utilization of coaxial lines along with the usual dc wiring. We report on the general design features and the microwave performance of a custom-made low-temperature sample probe, with a measurement bandwidth tested from dc to 20 GHz. Equipped with six coaxial cables, a heater, Hall and temperature sensors, the probe fits into a ⊘32 mm shaft. We present our setup, analyze its microwave performance, and describe two representative experiments enabled by this system. The proposed setup will be essential for a systematic study of the dc and ac response of the vortex dynamics in nanopatterned superconductors subject to combined dc and microwave stimuli. Besides, it will be valuable for the investigation of a broad class of nonlinear stochastic systems where a combination of dc and high-frequency ac driving in a wide temperature range is necessary.
DC Motor control using motor-generator set with controlled generator field
Belsterling, Charles A.; Stone, John
1982-01-01
A d.c. generator is connected in series opposed to the polarity of a d.c. power source supplying a d.c. drive motor. The generator is part of a motor-generator set, the motor of which is supplied from the power source connected to the motor. A generator field control means varies the field produced by at least one of the generator windings in order to change the effective voltage output. When the generator voltage is exactly equal to the d.c. voltage supply, no voltage is applied across the drive motor. As the field of the generator is reduced, the drive motor is supplied greater voltage until the full voltage of the d.c. power source is supplied when the generator has zero field applied. Additional voltage may be applied across the drive motor by reversing and increasing the reversed field on the generator. The drive motor may be reversed in direction from standstill by increasing the generator field so that a reverse voltage is applied across the d.c. motor.
Non-Carbohydrate Glycomimetics and Glycoprotein Surrogates as DC-SIGN Antagonists and Agonists
Prost, Lynne R.; Grim, Joseph C.; Tonelli, Marco; Kiessling, Laura L.
2012-01-01
An understanding of the biological roles of lectins will be advanced by ligands that can inhibit or even recruit lectin function. To this end, glycomimetics, non-carbohydrate ligands that function analogously to endogenous carbohydrates, are being sought. The advantage of having such ligands is illustrated by the many roles of the protein DC-SIGN. DC-SIGN is a C-type lectin displayed on dendritic cells, where it binds to mannosides and fucosides to mediate interactions with other host cells or bacterial or viral pathogens. DC-SIGN engagement can modulate host immune responses (e.g., suppress autoimmunity) or benefit pathogens (e.g., promote HIV dissemination). DC-SIGN can bind to glycoconjugates, internalize glycosylated cargo for antigen processing, and transduce signals. DC-SIGN ligands can serve as inhibitors as well as probes of the lectin’s function, so they are especially valuable for elucidating and controlling DC-SIGN’s roles in immunity. We previously reported a small molecule that embodies key features of the carbohydrates that bind DC-SIGN. Here, we demonstrate that this non-carbohydrate ligand acts as a true glycomimetic. Using NMR HSQC experiments, we found that the compound mimics saccharide ligands: It occupies the same carbohydrate-binding site and interacts with the same side chain residues on DC-SIGN. The glycomimetic also is functional. It had been shown previously to antagonize DC-SIGN function but here we use it to generate DC-SIGN agonists. Specifically, appending this glycomimetic to a protein scaffold affords a conjugate that elicits key cellular signaling responses. Thus, the glycomimetic can give rise to functional glycoprotein surrogates that elicit lectin-mediated signaling. PMID:22747463
Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor.
Schlitzer, Andreas; Heiseke, Alexander F; Einwächter, Henrik; Reindl, Wolfgang; Schiemann, Matthias; Manta, Calin-Petru; See, Peter; Niess, Jan-Hendrik; Suter, Tobias; Ginhoux, Florent; Krug, Anne B
2012-06-21
The ontogenic relationship between the common dendritic cell (DC) progenitor (CDP), the committed conventional DC precursor (pre-cDC), and cDC subpopulations in lymphoid and nonlymphoid tissues has been largely unraveled. In contrast, the sequential steps of plasmacytoid DC (pDC) development are less defined, and it is unknown at which developmental stage and location final commitment to the pDC lineage occurs. Here we show that CCR9(-) pDCs from murine BM which enter the circulation and peripheral tissues have a common DC precursor function in vivo in the steady state, in contrast to CCR9(+) pDCs which are terminally differentiated. On adoptive transfer, the fate of CCR9(-) pDC-like precursors is governed by the tissues they enter. In the BM and liver, most transferred CCR9(-) pDC-like precursors differentiate into CCR9(+) pDCs, whereas in peripheral lymphoid organs, lung, and intestine, they additionally give rise to cDCs. CCR9(-) pDC-like precursors which are distinct from pre-cDCs can be generated from the CDP. Thus, CCR9(-) pDC-like cells are novel CDP-derived circulating DC precursors with pDC and cDC potential. Their final differentiation into functionally distinct pDCs and cDCs depends on tissue-specific factors allowing adaptation to local requirements under homeostatic conditions.
DC and AC conductivity properties of bovine dentine hydroxyapatite (BDHA)
NASA Astrophysics Data System (ADS)
Dumludag, F.; Gunduz, O.; Kılıc, O.; Ekren, N.; Kalkandelen, C.; Ozbek, B.; Oktar, F. N.
2017-12-01
Bovine dentine bio-waste may be used as a potential natural source of hydroxyapatite (BDHA), thus extraction of bovine dentin hydroxyapatite (BDHA) from bio-waste is significantly important to fabricate in a simple, economically and environmentally preferable. DC and AC conductivity properties of BDHA were investigated depending on sintering temperature (1000ºC - 1300°C) in air and vacuum (<10-2 mbar) ambient at room temperature. DC conductivity measurements performed between -1 and 1 V. AC conductivity measurements performed in the frequency range of 40 Hz - 100 kHz. DC conductivity results showed that dc conductivity values of the BDHA decrease with increasing sintering temperature in air ambient. It is not observed remarkable/systematic behavior for ac conductivity depending on sintering temperature.
Radiofrequency amplifier based on a dc superconducting quantum interference device
Hilbert, Claude; Martinis, John M.; Clarke, John
1986-01-01
A low noise radiofrequency amplifier (10), using a dc SQUID (superconducting quantum interference device) as the input amplifying element. The dc SQUID (11) and an input coil (12) are maintained at superconductivity temperatures in a superconducting shield (13), with the input coil (12) inductively coupled to the superconducting ring (17) of the dc SQUID (11). A radiofrequency signal from outside the shield (13) is applied to the input coil (12), and an amplified radiofrequency signal is developed across the dc SQUID ring (17) and transmitted to exteriorly of the shield (13). A power gain of 19.5.+-.0.5 dB has been achieved with a noise temperature of 1.0.+-.0.4 K. at a frequency of 100 MHz.
Changyong, C; Sun, M; Li, H; Brockmeyer, N; Wu, Nan Ping
2010-09-24
Dendritic cells (DC) are the initiators and modulators of the immune responses. Some species of pathogenic microorganisms have developed immune evasion strategies by controlling antigen presentation function of DC. Simian virus 40 (SV40) is a DNA tumor virus of rhesus monkey origin. It can induce cell transformation and tumorigenesis in many vertebrate species, but often causes no visible effects and persists as a latent infection in rhesus monkeys under natural conditions. To investigate the interaction between SV40 and rhesus monkey DC, rhesus monkey peripheral blood monocyte-derived DC were induced using recombinant human Interleukin-4 (rhIL-4) and infective SV40, the phenotype and function of DC-specific intracellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN)(+) DC were analyzed by flow cytometry (FCM) and mixed lymphocyte reaction (MLR). Results showed that SV40 can down-regulate the expression of CD83 and CD86 on DC and impair DC-induced activation of T cell proliferation. These findings suggest that SV40 might also cause immune suppression by influencing differentiation and maturation of DC.
Phasor Domain Steady-State Modeling and Design of the DC–DC Modular Multilevel Converter
Yang, Heng; Qin, Jiangchao; Debnath, Suman; ...
2016-01-06
The DC-DC Modular Multilevel Converter (MMC), which originated from the AC-DC MMC, is an attractive converter topology for interconnection of medium-/high-voltage DC grids. This paper presents design considerations for the DC-DC MMC to achieve high efficiency and reduced component sizes. A steady-state mathematical model of the DC-DC MMC in the phasor-domain is developed. Based on the developed model, a design approach is proposed to size the components and to select the operating frequency of the converter to satisfy a set of design constraints while achieving high efficiency. The design approach includes sizing of the arm inductor, Sub-Module (SM) capacitor, andmore » phase filtering inductor along with the selection of AC operating frequency of the converter. The accuracy of the developed model and the effectiveness of the design approach are validated based on the simulation studies in the PSCAD/EMTDC software environment. The analysis and developments of this paper can be used as a guideline for design of the DC-DC MMC.« less
DcSto: carrot Stowaway-like elements are abundant, diverse, and polymorphic
USDA-ARS?s Scientific Manuscript database
We investigated nine families of Stowaway-like MITEs in the carrot genome, named DcSto1 to DcSto9. All of them were AT-rich and shared a highly conserved 6 bp-long TIR typical for Stowaways. The copy number of DcSto1 elements was estimated as ca. 5,000 per diploid genome. We observed preference for ...
Input current shaped ac-to-dc converters
NASA Technical Reports Server (NTRS)
1985-01-01
Input current shaping techniques for ac-to-dc converters were investigated. Input frequencies much higher than normal, up to 20 kHz were emphasized. Several methods of shaping the input current waveform in ac-to-dc converters were reviewed. The simplest method is the LC filter following the rectifier. The next simplest method is the resistor emulation approach in which the inductor size is determined by the converter switching frequency and not by the line input frequency. Other methods require complicated switch drive algorithms to construct the input current waveshape. For a high-frequency line input, on the order of 20 kHz, the simple LC cannot be discarded so peremptorily, since the inductor size can be compared with that for the resistor emulation method. In fact, since a dc regulator will normally be required after the filter anyway, the total component count is almost the same as for the resistor emulation method, in which the filter is effectively incorporated into the regulator.
A citywide breeding bird survey for Washington, DC
Hadidian, J.; Sauer, J.R.; Swarth, C.; Handly, P.; Droege, S.; Williams, C.; Huff, J.; Didden, G.
1997-01-01
`DC Birdscape' was initiated in 1993 to systematically count the birds occurring throughout Washington D.C. during the breeding season. It involved a coordinated planning effort and partnership between the Audubon Naturalist Society, the National Park Service, and the National Biological Survey, and engaged the participation of more than 100 volunteers. A method for rapidly assessing the status of bird populations over a large area was developed and incorporated into a Geographic Information System to allow a multidimensional analysis of species presence and abundance across a variety of urban land use areas. A total of 91 species were observed, with an estimated total number of 115, making Washington D.C. almost as `bird rich' as nearby suburban counties. Data from the study clearly indicate that avian species are not randomly distributed throughout the Washington D.C. metropolitan area, and show affinity, at least in part, to some of the most broadly recognized land use patterns that are commonly used to zone and classify urban areas under development schemes. This study represents a prototype that will allow efficient and economical monitoring of urban bird populations.
Anisotropic Thermal Behavior of Silicone Polymer, DC 745
DOE Office of Scientific and Technical Information (OSTI.GOV)
Adams, Jillian Cathleen; Torres, Joseph Angelo; Volz, Heather Michelle
In material applications, it is important to understand how polymeric materials behave in the various environments they may encounter. One factor governing polymer behavior is processing history. Differences in fabrication will result in parts with varied or even unintended properties. In this work, the thermal expansion behavior of silicone DC 745 is studied. Thermomechanical analysis (TMA) is used to determine changes in sample dimension resulting from changes in temperature. This technique can measure thermal events such as the linear coefficient of thermal expansion (CTE), melting, glass transitions, cure shrinkage, and internal relaxations. Using a thermomechanical analyzer (Q400 TMA), it ismore » determined that DC 745 expands anisotropically when heated. This means that the material has a different CTE depending upon which direction is being measured. In this study, TMA experiments were designed in order to confirm anisotropic thermal behavior in multiple DC 745 samples of various ages and lots. TMA parameters such as temperature ramp rate, preload force, and temperature range were optimized in order to ensure the most accurate and useful data. A better understanding of the thermal expansion of DC 745 will allow for more accurate modeling of systems using this material.« less
21 CFR 74.2711 - D&C Yellow No. 11.
Code of Federal Regulations, 2010 CFR
2010-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2711 D&C Yellow No. 11. (a) Identity and specifications. The color additive D&C Yellow No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2260 - D&C Orange No. 10.
Code of Federal Regulations, 2010 CFR
2010-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2260 D&C Orange No. 10. (a) Identity and specifications. The color additive D&C Orange No. 10 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2261 - D&C Orange No. 11.
Code of Federal Regulations, 2010 CFR
2010-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2261 D&C Orange No. 11. (a) Identity and specifications. The color additive D&C Orange No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2254 - D&C Orange No. 4.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2254 D&C Orange No. 4. (a) Identity and specifications. The color additive D&C Orange No. 4 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2708 - D&C Yellow No. 8.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2708 D&C Yellow No. 8. (a) Identity and specifications. The color additive D&C Yellow No. 8 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2707 - D&C Yellow No. 7.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2707 D&C Yellow No. 7. (a) Identity and specifications. The color additive D&C Yellow No. 7 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2254 - D&C Orange No. 4.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2254 D&C Orange No. 4. (a) Identity and specifications. The color additive D&C Orange No. 4 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2707 - D&C Yellow No. 7.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2707 D&C Yellow No. 7. (a) Identity and specifications. The color additive D&C Yellow No. 7 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2707 - D&C Yellow No. 7.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2707 D&C Yellow No. 7. (a) Identity and specifications. The color additive D&C Yellow No. 7 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2260 - D&C Orange No. 10.
Code of Federal Regulations, 2013 CFR
2013-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2260 D&C Orange No. 10. (a) Identity and specifications. The color additive D&C Orange No. 10 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2711 - D&C Yellow No. 11.
Code of Federal Regulations, 2013 CFR
2013-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2711 D&C Yellow No. 11. (a) Identity and specifications. The color additive D&C Yellow No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2260 - D&C Orange No. 10.
Code of Federal Regulations, 2012 CFR
2012-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2260 D&C Orange No. 10. (a) Identity and specifications. The color additive D&C Orange No. 10 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2711 - D&C Yellow No. 11.
Code of Federal Regulations, 2011 CFR
2011-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2711 D&C Yellow No. 11. (a) Identity and specifications. The color additive D&C Yellow No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2708 - D&C Yellow No. 8.
Code of Federal Regulations, 2011 CFR
2011-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2708 D&C Yellow No. 8. (a) Identity and specifications. The color additive D&C Yellow No. 8 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2707 - D&C Yellow No. 7.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2707 D&C Yellow No. 7. (a) Identity and specifications. The color additive D&C Yellow No. 7 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2261 - D&C Orange No. 11.
Code of Federal Regulations, 2014 CFR
2014-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2261 D&C Orange No. 11. (a) Identity and specifications. The color additive D&C Orange No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2708 - D&C Yellow No. 8.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2708 D&C Yellow No. 8. (a) Identity and specifications. The color additive D&C Yellow No. 8 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2261 - D&C Orange No. 11.
Code of Federal Regulations, 2013 CFR
2013-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2261 D&C Orange No. 11. (a) Identity and specifications. The color additive D&C Orange No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2708 - D&C Yellow No. 8.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2708 D&C Yellow No. 8. (a) Identity and specifications. The color additive D&C Yellow No. 8 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2254 - D&C Orange No. 4.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2254 D&C Orange No. 4. (a) Identity and specifications. The color additive D&C Orange No. 4 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2260 - D&C Orange No. 10.
Code of Federal Regulations, 2014 CFR
2014-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2260 D&C Orange No. 10. (a) Identity and specifications. The color additive D&C Orange No. 10 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2711 - D&C Yellow No. 11.
Code of Federal Regulations, 2012 CFR
2012-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2711 D&C Yellow No. 11. (a) Identity and specifications. The color additive D&C Yellow No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2261 - D&C Orange No. 11.
Code of Federal Regulations, 2012 CFR
2012-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2261 D&C Orange No. 11. (a) Identity and specifications. The color additive D&C Orange No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2254 - D&C Orange No. 4.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2254 D&C Orange No. 4. (a) Identity and specifications. The color additive D&C Orange No. 4 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2708 - D&C Yellow No. 8.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2708 D&C Yellow No. 8. (a) Identity and specifications. The color additive D&C Yellow No. 8 shall conform in identity and specifications to the requirements... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
21 CFR 74.2711 - D&C Yellow No. 11.
Code of Federal Regulations, 2014 CFR
2014-04-01
... COLOR ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2711 D&C Yellow No. 11. (a) Identity and specifications. The color additive D&C Yellow No. 11 shall conform in identity and specifications to the... coloring externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling...
Distributed control system for parallel-connected DC boost converters
Goldsmith, Steven
2017-08-15
The disclosed invention is a distributed control system for operating a DC bus fed by disparate DC power sources that service a known or unknown load. The voltage sources vary in v-i characteristics and have time-varying, maximum supply capacities. Each source is connected to the bus via a boost converter, which may have different dynamic characteristics and power transfer capacities, but are controlled through PWM. The invention tracks the time-varying power sources and apportions their power contribution while maintaining the DC bus voltage within the specifications. A central digital controller solves the steady-state system for the optimal duty cycle settings that achieve a desired power supply apportionment scheme for a known or predictable DC load. A distributed networked control system is derived from the central system that utilizes communications among controllers to compute a shared estimate of the unknown time-varying load through shared bus current measurements and bus voltage measurements.
Temperature-dependent performance of all-NbN DC-SQUID magnetometers
NASA Astrophysics Data System (ADS)
Liu, Quansheng; Wang, Huiwu; Zhang, Qiyu; Wang, Hai; Peng, Wei; Wang, Zhen
2017-05-01
Integrated NbN direct current superconducting quantum interference device (DC-SQUID) magnetometers were developed based on high-quality epitaxial NbN/AlN/NbN Josephson junctions for SQUID applications operating at high temperatures. We report the current-voltage and voltage-flux characteristics and the noise performance of the NbN DC-SQUIDs for temperatures ranging from 4.2 to 9 K. The critical current and voltage swing of the DC-SQUIDs decreased by 15% and 25%, respectively, as the temperature was increased from 4.2 to 9 K. The white flux noise of the DC-SQUID magnetometer at 1 kHz increased from 3.9 μΦ0/Hz1/2 at 4.2 K to 4.8 μΦ0/Hz1/2 at 9 K with 23% increase, corresponding to the magnetic field noise of 6.6 and 8.1 fT/Hz1/2, respectively. The results show that NbN DC-SQUIDs improve the tolerance of the operating temperatures and temperature fluctuations in SQUID applications.
NASA Astrophysics Data System (ADS)
Liu, K.; Hu, H.; Lei, J.; Hu, Y.; Zheng, Z.
2016-12-01
Most air-water plasma jets are rich in hydroxyl radicals (•OH), but the plasma has higher temperatures, compared to that of pure gas, especially when using air as working gas. In this paper, pulsating direct current (PDC) power was used to excite the air-water plasma jet to reduce plume temperature. In addition to the temperature, other differences between PDC and DC plasma jets are not yet clear. Thus, comparative studies of those plasmas are performed to evaluate characteristics, such as breakdown voltage, temperature, and reactive oxygen species. The results show that the plume temperature of PDC plasma is roughly 5-10 °C lower than that of DC plasma in the same conditions. The •OH content of PDC is lower than that of DC plasma, whereas the O content of PDC plasma is higher. The addition of water leads in an increase in the plume temperature and in the production of •OH with two types of power supplies. The production of O inversely shows a declining tendency with higher water ratio. The most important finding is that the PDC plasma with 100% water ratio achieves lower temperature and more abundant production of •OH and O, compared with DC plasma with 0% water ratio.
21 CFR 74.2328 - D&C Red No. 28.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2328 D&C Red No. 28. (a) Identity and specifications. The color additive D&C Red No. 28 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2330 - D&C Red No. 30.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2330 D&C Red No. 30. (a) Identity and specifications. The color additive D&C Red No. 30 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2327 - D&C Red No. 27.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2327 D&C Red No. 27. (a) Identity and specifications. The color additive D&C Red No. 27 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2328 - D&C Red No. 28.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2328 D&C Red No. 28. (a) Identity and specifications. The color additive D&C Red No. 28 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2328 - D&C Red No. 28.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2328 D&C Red No. 28. (a) Identity and specifications. The color additive D&C Red No. 28 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2330 - D&C Red No. 30.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2330 D&C Red No. 30. (a) Identity and specifications. The color additive D&C Red No. 30 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2330 - D&C Red No. 30.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2330 D&C Red No. 30. (a) Identity and specifications. The color additive D&C Red No. 30 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2327 - D&C Red No. 27.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2327 D&C Red No. 27. (a) Identity and specifications. The color additive D&C Red No. 27 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2330 - D&C Red No. 30.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2330 D&C Red No. 30. (a) Identity and specifications. The color additive D&C Red No. 30 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2327 - D&C Red No. 27.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2327 D&C Red No. 27. (a) Identity and specifications. The color additive D&C Red No. 27 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2327 - D&C Red No. 27.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2327 D&C Red No. 27. (a) Identity and specifications. The color additive D&C Red No. 27 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2328 - D&C Red No. 28.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2328 D&C Red No. 28. (a) Identity and specifications. The color additive D&C Red No. 28 shall conform in identity and specifications to the requirements of § 74... cosmetics generally in amounts consistent with current good manufacturing practice. (c) Labeling...
21 CFR 74.2317 - D&C Red No. 17.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2317 D&C Red No. 17. (a) Identity and specifications. The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2206 - D&C Green No. 6.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2206 D&C Green No. 6. (a) Identity and specifications. The color additive D&C Green No. 6 shall conform in identity and specifications to the requirements of § 74... applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling requirements. The...
21 CFR 74.2331 - D&C Red No. 31.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2331 D&C Red No. 31. (a) Identity and specifications. The color additive D&C Red No. 31 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2334 - D&C Red No. 34.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2334 D&C Red No. 34. (a) Identity and specifications. The color additive D&C Red No. 34 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2104 - D&C Blue No. 4.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2104 D&C Blue No. 4. (a) Identity and specifications. The color additive D&C Blue No. 4 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.1321 - D&C Red No. 21.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1321 D&C Red No. 21. (a) Identity. (1) The color additive D&C... (CAS Reg. No. 25709-84-6). The color additive is manufactured by brominating fluorescein with elemental... anhydride. The fluorescein is isolated and partially purified prior to bromination. (2) Color additive...
21 CFR 74.2317 - D&C Red No. 17.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2317 D&C Red No. 17. (a) Identity and specifications. The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2334 - D&C Red No. 34.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2334 D&C Red No. 34. (a) Identity and specifications. The color additive D&C Red No. 34 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2206 - D&C Green No. 6.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2206 D&C Green No. 6. (a) Identity and specifications. The color additive D&C Green No. 6 shall conform in identity and specifications to the requirements of § 74... applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling requirements. The...
21 CFR 74.2317 - D&C Red No. 17.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2317 D&C Red No. 17. (a) Identity and specifications. The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2334 - D&C Red No. 34.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2334 D&C Red No. 34. (a) Identity and specifications. The color additive D&C Red No. 34 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2206 - D&C Green No. 6.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2206 D&C Green No. 6. (a) Identity and specifications. The color additive D&C Green No. 6 shall conform in identity and specifications to the requirements of § 74... applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling requirements. The...
21 CFR 74.2206 - D&C Green No. 6.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2206 D&C Green No. 6. (a) Identity and specifications. The color additive D&C Green No. 6 shall conform in identity and specifications to the requirements of § 74... applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling requirements. The...
21 CFR 74.2331 - D&C Red No. 31.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2331 D&C Red No. 31. (a) Identity and specifications. The color additive D&C Red No. 31 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2331 - D&C Red No. 31.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2331 D&C Red No. 31. (a) Identity and specifications. The color additive D&C Red No. 31 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2331 - D&C Red No. 31.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2331 D&C Red No. 31. (a) Identity and specifications. The color additive D&C Red No. 31 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2317 - D&C Red No. 17.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2317 D&C Red No. 17. (a) Identity and specifications. The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
21 CFR 74.2334 - D&C Red No. 34.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2334 D&C Red No. 34. (a) Identity and specifications. The color additive D&C Red No. 34 shall conform in identity and specifications to the requirements of § 74... externally applied cosmetics in amounts consistent with good manufacturing practice. (c) Labeling. The label...
NASA Astrophysics Data System (ADS)
Almasoudi, Fahad M.; Alatawi, Khaled S.; Matin, Mohammad
2016-09-01
The development of Wide band gap (WBG) power devices has been attracted by many commercial companies to be available in the market because of their enormous advantages over the traditional Si power devices. An example of WBG material is SiC, which offers a number of advantages over Si material. For example, SiC has the ability of blocking higher voltages, reducing switching and conduction losses and supports high switching frequency. Consequently, SiC power devices have become the affordable choice for high frequency and power application. The goal of this paper is to study the performance of 4.5 kW, 200 kHz, 600V DC-DC boost converter operating in continuous conduction mode (CCM) for PV applications. The switching behavior and turn on and turn off losses of different switching power devices such as SiC MOSFET, SiC normally ON JFET and Si MOSFET are investigated and analyzed. Moreover, a detailed comparison is provided to show the overall efficiency of the DC-DC boost converter with different switching power devices. It is found that the efficiency of SiC power switching devices are higher than the efficiency of Si-based switching devices due to low switching and conduction losses when operating at high frequencies. According to the result, the performance of SiC switching power devices dominate the conventional Si power devices in terms of low losses, high efficiency and high power density. Accordingly, SiC power switching devices are more appropriate for PV applications where a converter of smaller size with high efficiency, and cost effective is required.
NASA Astrophysics Data System (ADS)
Al-bayati, Ali M. S.; Alharbi, Salah S.; Alharbi, Saleh S.; Matin, Mohammad
2017-08-01
A highly efficient high step-up dc-dc converter is the major requirement in the integration of low voltage renewable energy sources, such as photovoltaic panel module and fuel cell stacks, with a load or utility. This paper presents the development of an efficient dc-dc single-ended primary-inductor converter (SEPIC) for high step-up applications. Three SEPIC converters are designed and studied using different combinations of power devices: a combination based on all Si power devices using a Si-MOSFET and a Si-diode and termed as Si/Si, a combination based on a hybrid of Si and SiC power devices using the Si-MOSFET and a SiC-Schottky diode and termed as Si/SiC, and a combination based on all SiC power devices using a SiC-MOSFET and the SiC-Schottky diode and termed as SiC/SiC. The switching behavior of the Si-MOSFET and SiC-MOSFET is characterized and analyzed within the different combinations at the converter level. The effect of the diode type on the converter's overall performance is also discussed. The switching energy losses, total power losses, and the overall performance effciency of the converters are measured and reported under different switching frequencies. Furthermore, the potential of the designed converters to operate efficiently at a wide range of input voltages and output powers is studied. The analysis and results show an outstanding performance efficiency of the designed SiC/SiC based converter under a wide range of operating conditions.
76 FR 52566 - Drawbridge Operation Regulations; Anacostia River, Washington, DC
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-23
... Lift Bridge across the Anacostia River, mile 3.4, at Washington, DC. This deviation will test a change... regulations for the CSX Railroad Vertical Lift Bridge, across the Anacostia River, mile 3.4, at Washington, DC...
NASA Astrophysics Data System (ADS)
Power, Christopher; Tsourlos, Panagiotis; Ramasamy, Murugan; Nivorlis, Aristeidis; Mkandawire, Martin
2018-03-01
Mine waste rock piles (WRPs) can contain sulfidic minerals whose interaction with oxygen and water can generate acid mine drainage (AMD). Thus, WRPs can be a long-term source of environmental pollution. Since the generation of AMD and its release into the environment is dependent on the net volume and bulk composition of waste rock, effective characterization of WRPs is necessary for successful remedial design and monitoring. In this study, a combined DC resistivity and induced polarization (DC-IP) approach was employed to characterize an AMD-generating WRP in the Sydney Coalfield, Nova Scotia, Canada. Two-dimensional (2D) DC-IP imaging with 6 survey lines was performed to capture the full WRP landform. 2D DC results indicated a highly heterogeneous and moderately conductive waste rock underlain by a resistive bedrock containing numerous fractures. 2D IP (chargeability) results identified several highly-chargeable regions within the waste, with normalized chargeability delineating regions specific to waste mineralogy only. Three-dimensional (3D) DC-IP imaging, using 17 parallel lines on the plateau of the pile, was then used to focus on the composition of the waste rock. The full 3D inverted DC-IP distributions were used to identify coincident and continuous zones (isosurfaces) of low resistivity (<30 Ω-m) and high normalized chargeability (>0.4 mS/m) that were inferred as generated AMD (leachate) and stored AMD (sulfides), respectively. Integrated geological, hydrogeological and geochemical data increased confidence in the geoelectrical interpretations. Knowledge on the location of potentially more reactive waste material is extremely valuable for improved long-term AMD monitoring at the WRP.
ERIC Educational Resources Information Center
Jeffery, Rondo N.; Farhang, Amiri
2016-01-01
The classroom jumping ring demonstration is nearly always performed using alternating current (AC), in which the ring jumps or flies off the extended iron core when the switch is closed. The ring jumps higher when cooled with liquid nitrogen (LN2). We have performed experiments using DC to power the solenoid and find similarities and significant…
Mutations That Stimulate flhDC Expression in Escherichia coli K-12.
Fahrner, Karen A; Berg, Howard C
2015-10-01
Motility is a beneficial attribute that enables cells to access and explore new environments and to escape detrimental ones. The organelle of motility in Escherichia coli is the flagellum, and its production is initiated by the activating transcription factors FlhD and FlhC. The expression of these factors by the flhDC operon is highly regulated and influenced by environmental conditions. The flhDC promoter is recognized by σ(70) and is dependent on the transcriptional activator cyclic AMP (cAMP)-cAMP receptor protein complex (cAMP-CRP). A number of K-12 strains exhibit limited motility due to low expression levels of flhDC. We report here a large number of mutations that stimulate flhDC expression in such strains. They include single nucleotide changes in the -10 element of the promoter, in the promoter spacer, and in the cAMP-CRP binding region. In addition, we show that insertion sequence (IS) elements or a kanamycin gene located hundreds of base pairs upstream of the promoter can effectively enhance transcription, suggesting that the topology of a large upstream region plays a significant role in the regulation of flhDC expression. None of the mutations eliminated the requirement for cAMP-CRP for activation. However, several mutations allowed expression in the absence of the nucleoid organizing protein, H-NS, which is normally required for flhDC expression. The flhDC operon of Escherichia coli encodes transcription factors that initiate flagellar synthesis, an energetically costly process that is highly regulated. Few deregulating mutations have been reported thus far. This paper describes new single nucleotide mutations that stimulate flhDC expression, including a number that map to the promoter spacer region. In addition, this work shows that insertion sequence elements or a kanamycin gene located far upstream from the promoter or repressor binding sites also stimulate transcription, indicating a role of regional topology in the regulation of flhDC
Chen, Hsi-Chao; Jan, Der-Jun; Luo, Yu-Siang; Huang, Kuo-Ting
2014-02-01
Research was undertaken to investigate the electrochromic and optical properties of tungsten oxide (WO3) films deposited by introducing hydrogen with a direct current (DC) and pulsed DC sputtering. The results show that WO3 films have optimum electrochromic properties at a hydrogen flow of 4 and 3 sccm for DC and pulsed DC, respectively. In the Raman spectra, the peak intensity increased with the increase of hydrogen flow at both 770 cm1 and 950 cm(-1) peaks, which resulted in bonds of W(6+)-O and W(6+)=O, respectively. Simultaneously, the transmittance (ΔT550 nm) variations were 65.6% and 64.4%, and the average transmittance (ΔT400-500 nm) variations were 56.7% and 56.4% for DC and pulsed DC, respectively. The bleached/colored ability of the cyclic voltammograms (CVs) was DC>pulsed DC, and the resistances of AC impedance were pulsed DC>DC.
Plasmacytoid pre-dendritic cells (pDC): from molecular pathways to function and disease association.
Alculumbre, Solana; Raieli, Salvatore; Hoffmann, Caroline; Chelbi, Rabie; Danlos, François-Xavier; Soumelis, Vassili
2018-02-19
Plasmacytoid pre-dendritic cells (pDC) are a specialized DC population with a great potential to produce large amounts of type I interferon (IFN). pDC are involved in the initiation of antiviral immune responses through their interaction with innate and adaptive immune cell populations. In a context-dependent manner, pDC activation can induce their differentiation into mature DC able to induce both T cell activation or tolerance. In this review, we described pDC functions during immune responses and their implication in the clearance or pathogenicity of human diseases during infection, autoimmunity, allergy and cancer. We discuss recent advances in the field of pDC biology and their implication for future studies. Copyright © 2018 Elsevier Ltd. All rights reserved.
Maximum power point tracking for photovoltaic applications by using two-level DC/DC boost converter
NASA Astrophysics Data System (ADS)
Moamaei, Parvin
Recently, photovoltaic (PV) generation is becoming increasingly popular in industrial applications. As a renewable and alternative source of energy they feature superior characteristics such as being clean and silent along with less maintenance problems compared to other sources of the energy. In PV generation, employing a Maximum Power Point Tracking (MPPT) method is essential to obtain the maximum available solar energy. Among several proposed MPPT techniques, the Perturbation and Observation (P&O;) and Model Predictive Control (MPC) methods are adopted in this work. The components of the MPPT control system which are P&O; and MPC algorithms, PV module and high gain DC-DC boost converter are simulated in MATLAB Simulink. They are evaluated theoretically under rapidly and slowly changing of solar irradiation and temperature and their performance is shown by the simulation results, finally a comprehensive comparison is presented.
Design of Energy Storage Reactors for Dc-To-Dc Converters. Ph.D. Thesis
NASA Technical Reports Server (NTRS)
Chen, D. Y.
1975-01-01
Two methodical approaches to the design of energy-storage reactors for a group of widely used dc-to-dc converters are presented. One of these approaches is based on a steady-state time-domain analysis of piecewise-linearized circuit models of the converters, while the other approach is based on an analysis of the same circuit models, but from an energy point of view. The design procedure developed from the first approach includes a search through a stored data file of magnetic core characteristics and results in a list of usable reactor designs which meet a particular converter's requirements. Because of the complexity of this procedure, a digital computer usually is used to implement the design algorithm. The second approach, based on a study of the storage and transfer of energy in the magnetic reactors, leads to a straightforward design procedure which can be implemented with hand calculations. An equation to determine the lower-bound volume of workable cores for given converter design specifications is derived. Using this computer lower-bound volume, a comparative evaluation of various converter configurations is presented.
Trends and determinants of cycling in the Washington, DC region.
DOT National Transportation Integrated Search
2011-01-01
This report analyzes cycling trends, policies, and commuting in the Washington, DC area. The analysis is divided into two parts. : Part 1 focuses on cycling trends and policies in Washington (DC), Alexandria (VA), Arlington County (VA), Fairfax Count...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-06
.... SUMMARY: We are adopting a new airworthiness directive (AD) for the products listed above. This AD requires repetitive inspections for cracking of the left and right upper center skin panels of the... Building Ground Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC 20590. FOR FURTHER...
Studies of ZVS soft switching of dual-active-bridge isolated bidirectional DC-DC converters
NASA Astrophysics Data System (ADS)
Xu, Fei; Zhao, Feng; Shi, Qibiao; Wen, Xuhui
2018-05-01
To operate dual-active-bridge isolated bidirectional dc- dc converter (DAB) at high efficiency, the two bridge switches must operate with Zero-Voltage-Switching (ZVS) over as wide an operating range as possible. This paper proposes a new perspective on realizing ZVS in dead-time. An exact theoretical analysis and mathematical mode is built to explain the process of ZVS switching in dead-time under Single Phase Shift (SPS) control strategy. In order to assure the two bridge switches operate on soft switching, every SPS switching point is analyzed. Generally, dead-time will be determined when the power electronic devices is selected. The key factor to realizing ZVS is the size of the end time of resonance comparing to dead-time. Through detailed analysis, it can obtain the conditions of all switches achieving ZVS turn-on and turn-off. Finally, simulation validates the theoretical analysis and some advice are given to realize the ZVS soft switching.
Experimental Investigation of DC-Bias Related Core Losses in a Boost Inductor (Postprint)
2014-08-01
dc bias-flux conditions. These dc bias conditions result in distorted hysteresis loops , increased core losses, and have been shown to be independent...These dc bias conditions result in dis- torted hysteresis loops , increased core losses, and have been shown to be independent of core material. The...controllable converter load currents, this topology is ideal to study dc-related losses. Inductor core hysteresis loop characterization was accomplished
Strong mechanically induced effects in DC current-biased suspended Josephson junctions
NASA Astrophysics Data System (ADS)
McDermott, Thomas; Deng, Hai-Yao; Isacsson, Andreas; Mariani, Eros
2018-01-01
Superconductivity is a result of quantum coherence at macroscopic scales. Two superconductors separated by a metallic or insulating weak link exhibit the AC Josephson effect: the conversion of a DC voltage bias into an AC supercurrent. This current may be used to activate mechanical oscillations in a suspended weak link. As the DC-voltage bias condition is remarkably difficult to achieve in experiments, here we analyze theoretically how the Josephson effect can be exploited to activate and detect mechanical oscillations in the experimentally relevant condition with purely DC current bias. We unveil how changing the strength of the electromechanical coupling results in two qualitatively different regimes showing dramatic effects of the oscillations on the DC-voltage characteristic of the device. These include the appearance of Shapiro-type plateaus for weak coupling and a sudden mechanically induced retrapping for strong coupling. Our predictions, measurable in state-of-the-art experimental setups, allow the determination of the frequency and quality factor of the resonator using DC only techniques.
21 CFR 74.1339 - D&C Red No. 39.
Code of Federal Regulations, 2010 CFR
2010-04-01
... As), not more than 3 parts per million. Total color, not less than 95.0 percent. (c) Uses and... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1339 D&C Red No. 39. (a) Identity. (1) The color additive D&C...
The Proving Grounds: School "Rheeform" in Washington, D.C.
ERIC Educational Resources Information Center
Dingerson, Leigh
2010-01-01
Washington, D.C., is leading the transformation of urban public education across the country--at least according to "Time" magazine, which featured D.C. Schools Chancellor Michelle Rhee on its cover, wearing black and holding a broom. But there is nothing remarkably visionary going on in Washington. The model of school reform that is…
NASA Technical Reports Server (NTRS)
Burns, W. W., III; Wilson, T. G.
1976-01-01
State-plane analysis techniques are employed to study the voltage step up energy storage dc-to-dc converter. Within this framework, an example converter operating under the influence of a constant on time and a constant frequency controller is examined. Qualitative insight gained through this approach is used to develop a conceptual free running control law for the voltage step up converter which can achieve steady state operation in one on/off cycle of control. Digital computer simulation data is presented to illustrate and verify the theoretical discussions presented.
Advanced dc motor controller for battery-powered electric vehicles
NASA Technical Reports Server (NTRS)
Belsterling, C. A.
1981-01-01
A motor generation set is connected to run from the dc source and generate a voltage in the traction motor armature circuit that normally opposes the source voltage. The functional feasibility of the concept is demonstrated with tests on a Proof of Principle System. An analog computer simulation is developed, validated with the results of the tests, applied to predict the performance of a full scale Functional Model dc Controller. The results indicate high efficiencies over wide operating ranges and exceptional recovery of regenerated energy. The new machine integrates both motor and generator on a single two bearing shaft. The control strategy produces a controlled bidirectional plus or minus 48 volts dc output from the generator permitting full control of a 96 volt dc traction motor from a 48 volt battery, was designed to control a 20 hp traction motor. The controller weighs 63.5 kg (140 lb.) and has a peak efficiency of 90% in random driving modes and 96% during the SAE J 227a/D driving cycle.
High power density dc-to-dc converters for aerospace applications
NASA Technical Reports Server (NTRS)
Divan, Deepakraj M.
1990-01-01
Three dc-to-dc converter topologies aimed at high-power high-frequency applications are introduced. Major system parasitics, namely, the leakage inductance of the transformer and the device output capacitance are efficiently utilized. Of the three circuits, the single-phase and three-phase versions of the dual active bridge topology demonstrate minimal stresses, better utilization of the transformer, bidirectional, and buck-boost modes of operation. All circuits operate at a constant switching frequency, thus simplifying design of the reactive elements. The power transfer characteristics and soft-switching regions on the Vout-Iout plane are identified. Two coaxial transformers with different cross-sections were built for a rating of 50 kVA. Based on the single-phase dual active bridge topology, a 50 kW, 50 kHz converter operating at an input voltage of 200 Vdc and an output voltage of 1600 Vdc was fabricated. Characteristics of current-fed output make the dual active bridge topologies amenable to paralleling and hence extension to megawatt power levels. Projections to a 1 MW system operating from a 500 Vdc input, at an output voltage of 10 kVdc and a switching frequency of 50 kHz, using MOS-controlled thyristors, coaxially wound transformers operating at three times the present current density with cooling, and multilayer ceramic capacitors, suggests an overall power density of 0.075 to 0.08 kg/kW and an overall efficiency of 96 percent.
Simulation and Performance of Brushless DC Motor Actuators.
1985-12-01
4. MacMillan, P.M., "A CSMP Commutation Model for Design Study of a ’.... Brushless DC Motor Power Conditioner for a Cruise Missile Fin Control...8217. ,. ~-4..T NPS69-85-028 .r * N NAVAL POSTGRADUATE SCHOOL Monterey, California DTIC FEB4 1986 SIMULATION AND PERFORMANCE OF BRUSHLESS DC...S. TYPE OF REPORT & PERIOD COVERED Progress Re rSimulation and Performance of Brushless DCPrgesRpt Motor Actuators 111 PERFORMING ORG. REPORT NUMBER
Programmable Gain Amplifiers with DC Suppression and Low Output Offset for Bioelectric Sensors
Carrera, Albano; de la Rosa, Ramón; Alonso, Alonso
2013-01-01
DC-offset and DC-suppression are key parameters in bioelectric amplifiers. However, specific DC analyses are not often explained. Several factors influence the DC-budget: the programmable gain, the programmable cut-off frequencies for high pass filtering and, the low cut-off values and the capacitor blocking issues involved. A new intermediate stage is proposed to address the DC problem entirely. Two implementations were tested. The stage is composed of a programmable gain amplifier (PGA) with DC-rejection and low output offset. Cut-off frequencies are selectable and values from 0.016 to 31.83 Hz were tested, and the capacitor deblocking is embedded in the design. Hence, this PGA delivers most of the required gain with constant low output offset, notwithstanding the gain or cut-off frequency selected. PMID:24084109
In Vitro and In Vivo Antibacterial Activities of DC-159a, a New Fluoroquinolone▿
Hoshino, Kazuki; Inoue, Kazue; Murakami, Yoichi; Kurosaka, Yuichi; Namba, Kenji; Kashimoto, Yoshinori; Uoyama, Saori; Okumura, Ryo; Higuchi, Saito; Otani, Tsuyoshi
2008-01-01
DC-159a is a new 8-methoxy fluoroquinolone that possesses a broad spectrum of antibacterial activity, with extended activity against gram-positive pathogens, especially streptococci and staphylococci from patients with community-acquired infections. DC-159a showed activity against Streptococcus spp. (MIC90, 0.12 μg/ml) and inhibited the growth of 90% of levofloxacin-intermediate and -resistant strains at 1 μg/ml. The MIC90s of DC-159a against Staphylococcus spp. were 0.5 μg/ml or less. Against quinolone- and methicillin-resistant Staphylococcus aureus strains, however, the MIC90 of DC-159a was 8 μg/ml. DC-159a was the most active against Enterococcus spp. (MIC90, 4 to 8 μg/ml) and was more active than the marketed fluoroquinolones, such as levofloxacin, ciprofloxacin, and moxifloxacin. The MIC90s of DC-159a against Haemophilus influenzae, Moraxella catarrhalis, and Klebsiella pneumoniae were 0.015, 0.06, and 0.25 μg/ml, respectively. The activity of DC-159a against Mycoplasma pneumoniae was eightfold more potent than that of levofloxacin. The MICs of DC-159a against Chlamydophila pneumoniae were comparable to those of moxifloxacin, and DC-159a was more potent than levofloxacin. The MIC90s of DC-159a against Peptostreptococcus spp., Clostridium difficile, and Bacteroides fragilis were 0.5, 4, and 2 μg/ml, respectively; and among the quinolones tested it showed the highest level of activity against anaerobic organisms. DC-159a demonstrated rapid bactericidal activity against quinolone-resistant Streptococcus pneumoniae strains both in vitro and in vivo. In vitro, DC-159a showed faster killing than moxifloxacin and garenoxacin. The bactericidal activity of DC-159a in a murine muscle infection model was revealed to be superior to that of moxifloxacin. These activities carried over to the in vivo efficacy in the murine pneumonia model, in which treatment with DC-159a led to bactericidal activity superior to those of the other agents tested. PMID:17938194
NASA Technical Reports Server (NTRS)
1973-01-01
Analyses and design studies were conducted on the technical and economic feasibility of installing the JT8D-109 refan engine on the DC-9 aircraft. Design criteria included minimum change to the airframe to achieve desired acoustic levels. Several acoustic configurations were studied with two selected for detailed investigations. The minimum selected acoustic treatment configuration results in an estimated aircraft weight increase of 608 kg (1,342 lb) and the maximum selected acoustic treatment configuration results in an estimated aircraft weight increase of 809 kg (1,784 lb). The range loss for the minimum and maximum selected acoustic treatment configurations based on long range cruise at 10 668 m (35,000 ft) altitude with a typical payload of 6 804 kg (15,000 lb) amounts to 54 km (86 n. mi.) respectively. Estimated reduction in EPNL's for minimum selected treatment show 8 EPNdB at approach, 12 EPNdB for takeoff with power cutback, 15 EPNdB for takeoff without power cutback and 12 EPNdB for sideline using FAR Part 36. Little difference was estimated in EPNL between minimum and maximum treatments due to reduced performance of maximum treatment. No major technical problems were encountered in the study. The refan concept for the DC-9 appears technically feasible and economically viable at approximately $1,000,000 per airplane. An additional study of the installation of JT3D-9 refan engine on the DC-8-50/61 and DC-8-62/63 aircraft is included. Three levels of acoustic treatment were suggested for DC-8-50/61 and two levels for DC-8-62/63. Results indicate the DC-8 technically can be retrofitted with refan engines for approximately $2,500,000 per airplane.
Very low noise AC/DC power supply systems for large detector arrays.
Arnaboldi, C; Baù, A; Carniti, P; Cassina, L; Giachero, A; Gotti, C; Maino, M; Passerini, A; Pessina, G
2015-12-01
In this work, we present the first part of the power supply system for the CUORE and LUCIFER arrays of bolometric detectors. For CUORE, it consists of AC/DC commercial power supplies (0-60 V output) followed by custom DC/DC modules (48 V input, ±5 V to ±13.5 V outputs). Each module has 3 floating and independently configurable output voltages. In LUCIFER, the AC/DC + DC/DC stages are combined into a commercial medium-power AC/DC source. At the outputs of both setups, we introduced filters with the aim of lowering the noise and to protect the following stages from high voltage spikes that can be generated by the energy stored in the cables after the release of accidental short circuits. Output noise is very low, as required: in the 100 MHz bandwidth the RMS level is about 37 μV(RMS) (CUORE setup) and 90 μV(RMS) (LUCIFER setup) at a load of 7 A, with a negligible dependence on the load current. Even more importantly, high frequency switching disturbances are almost completely suppressed. The efficiency of both systems is above 85%. Both systems are completely programmable and monitored via CAN bus (optically coupled).
21 CFR 74.1602 - D&C Violet No. 2.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Violet No. 2. 74.1602 Section 74.1602 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1602 D&C Violet No. 2. (a) Identity. (1) The color additive D...
21 CFR 74.1260 - D&C Orange No. 10.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Orange No. 10. 74.1260 Section 74.1260 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1260 D&C Orange No. 10. (a) Identity. (1) The color...
21 CFR 74.1254 - D&C Orange No. 4.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Orange No. 4. 74.1254 Section 74.1254 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1254 D&C Orange No. 4. (a) Identity. (1) the color additive D...
21 CFR 74.1261 - D&C Orange No. 11.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Orange No. 11. 74.1261 Section 74.1261 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1261 D&C Orange No. 11. (a) Identity. (1) The color...
21 CFR 74.1255 - D&C Orange No. 5.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Orange No. 5. 74.1255 Section 74.1255 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1255 D&C Orange No. 5. (a) Identity. (1) the color additive D...
21 CFR 74.3230 - D&C Red No. 17.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 17. 74.3230 Section 74.3230 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR.... The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of...
21 CFR 74.3230 - D&C Red No. 17.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false D&C Red No. 17. 74.3230 Section 74.3230 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR.... The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of...
21 CFR 74.3710 - D&C Yellow No. 10.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 1 2013-04-01 2013-04-01 false D&C Yellow No. 10. 74.3710 Section 74.3710 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3710 D&C Yellow No. 10. (a) Identity. The...
21 CFR 74.3710 - D&C Yellow No. 10.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false D&C Yellow No. 10. 74.3710 Section 74.3710 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3710 D&C Yellow No. 10. (a) Identity. The...
21 CFR 74.3230 - D&C Red No. 17.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 1 2012-04-01 2012-04-01 false D&C Red No. 17. 74.3230 Section 74.3230 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR.... The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of...
21 CFR 74.3230 - D&C Red No. 17.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Red No. 17. 74.3230 Section 74.3230 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR.... The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of...
21 CFR 74.3230 - D&C Red No. 17.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 1 2013-04-01 2013-04-01 false D&C Red No. 17. 74.3230 Section 74.3230 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR.... The color additive D&C Red No. 17 shall conform in identity and specifications to the requirements of...
21 CFR 74.3710 - D&C Yellow No. 10.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 1 2012-04-01 2012-04-01 false D&C Yellow No. 10. 74.3710 Section 74.3710 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3710 D&C Yellow No. 10. (a) Identity. The...
21 CFR 74.1330 - D&C Red No. 30.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Red No. 30. 74.1330 Section 74.1330 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR... this chapter as safe for use in color additive mixtures for coloring drugs. (b) Specifications. D&C Red...
21 CFR 74.1330 - D&C Red No. 30.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 30. 74.1330 Section 74.1330 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR... this chapter as safe for use in color additive mixtures for coloring drugs. (b) Specifications. D&C Red...
21 CFR 74.2330 - D&C Red No. 30.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 30. 74.2330 Section 74.2330 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1330 (a)(1) and (b). (b) Uses and restrictions. D&C Red No. 30 may be safely used for coloring...
21 CFR 74.2328 - D&C Red No. 28.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 28. 74.2328 Section 74.2328 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1328 (a)(1) and (b). (b) Uses and restrictions. D&C Red No. 28 may be safely used for coloring...
21 CFR 74.2317 - D&C Red No. 17.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 17. 74.2317 Section 74.2317 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1317(a)(1) and (b). (b) Uses and restrictions. D&C Red No. 17 may be safely used for coloring...
21 CFR 82.1255 - D&C Orange No. 5.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Orange No. 5. 82.1255 Section 82.1255 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF CERTIFIED...) The color additive D&C Orange No. 5. may be safely used for coloring externally applied drugs in...
21 CFR 74.2327 - D&C Red No. 27.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 27. 74.2327 Section 74.2327 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1327 (a)(1) and (b). (b) Uses and restrictions. D&C Red No. 27 may be safely used for coloring...
21 CFR 74.2206 - D&C Green No. 6.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Green No. 6. 74.2206 Section 74.2206 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1206 (a) and (b). (b) Uses and restrictions. D&C Green No. 6 may be safely used for coloring externally...
21 CFR 74.2104 - D&C Blue No. 4.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Blue No. 4. 74.2104 Section 74.2104 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1104(a)(1) and (b). (b) Uses and restrictions. D&C Blue No. 4 may be safely used for coloring...
21 CFR 74.2208 - D&C Green No. 8.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Green No. 8. 74.2208 Section 74.2208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1208(a)(1) and (b). (b) Uses and restrictions. D&C Green No. 8 may be safely used for coloring...
21 CFR 74.2331 - D&C Red No. 31.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 31. 74.2331 Section 74.2331 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1331(a)(1) and (b). (b) Uses and restrictions. D&C Red No. 31 may be safely used for coloring...
21 CFR 74.2208 - D&C Green No. 8.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Green No. 8. 74.2208 Section 74.2208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1208(a)(1) and (b). (b) Uses and restrictions. D&C Green No. 8 may be safely used for coloring...
21 CFR 82.1255 - D&C Orange No. 5.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Orange No. 5. 82.1255 Section 82.1255 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF CERTIFIED...) The color additive D&C Orange No. 5. may be safely used for coloring externally applied drugs in...
21 CFR 74.2334 - D&C Red No. 34.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 34. 74.2334 Section 74.2334 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR....1334(a)(1) and (b). (b) Uses and restrictions. D&C Red No. 34 may be safely used for coloring...
21 CFR 82.1602 - D&C Violet No. 2.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Violet No. 2. 82.1602 Section 82.1602 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF CERTIFIED... additive D&C Violet No. 2 shall conform in identity and specifications to the requirements of § 74.1602(a...
21 CFR 74.1711 - D&C Yellow No. 11.
Code of Federal Regulations, 2010 CFR
2010-04-01
... listed in part 73 of this chapter as safe for use in color additive mixtures for coloring externally... part per million. Total color, not less than 96 percent. (c) Uses and restrictions. D&C Yellow No. 11... COLOR ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1711 D&C Yellow No. 11. (a) Identity. (1) The color...
NASA Technical Reports Server (NTRS)
Chen, D. Y.; Owen, H. A., Jr.; Wilson, T. G.
1980-01-01
This paper presents an algorithm and equations for designing the energy-storage reactor for dc-to-dc converters which are constrained to operate in the discontinuous-reactor-current mode. This design procedure applied to the three widely used single-winding configurations: the voltage step-up, the current step-up, and the voltage-or-current step-up converters. A numerical design example is given to illustrate the use of the design algorithm and design equations.
DC-8 scanning lidar characterization of aircraft contrails and cirrus clouds
NASA Technical Reports Server (NTRS)
Nielsen, Norman B.; Uthe, Edward E. (Principal Investigator)
1996-01-01
A Subsonic Assessment (SASS) element of the overall Atmospheric Effects of Aviation Project (AEAP) was initiated by NASA to assess the atmospheric impact of subsonic aircraft. SRI was awarded a project to develop and test a scanning backscatter lidar for installation on the NASA DC-8 (year 1), participate in the Subsonic Aircraft: Contrail and Cloud Effects Special Study (SUCCESS) field program (year 2), and conduct a comprehensive analysis of field data (year 3). A scanning mirror pod attached to the DC-8 aircraft provides for scanning lidar observations ahead of the DC-8 and fixed-angle upward or downward observations. The lidar system installed within the DC-8 transmits 275 MJ at 1.06 gm wavelength or about 130 mJ at 1.06 and 0.53 gm simultaneously. Range-resolved aerosol backscatter is displayed in real time in terms of cloud/contrail spatial distributions. The objectives of the project are to map contrail/cloud vertical distributions ahead of DC-8; provide DC-8 guidance into enhanced scattering layers; document DC-8 flight path intersection of contrail and cloud geometries (in-situ measurement positions relative to cloud/contrail shape and an extension of in-situ measurements into the vertical -- integrated contrail/cloud properties); analyze contrail/cloud radiative properties with LIRAD (combined lidar and radiometry) technique; evaluate mean particle sizes of aircraft emissions from two-wavelength observations; study contrail/cloud interactions, diffusion, and mass decay/growth; and make observations in the near-field of aircraft engine emissions. The scanning mirror pod may also provide a scanning capability for other remote sensing instruments.
Cascaded Quadruple Active Bridge Structures for Multilevel DC to Three-Phase AC Conversion
DOE Office of Scientific and Technical Information (OSTI.GOV)
Johnson, Brian B; Achanta, Prasanta K; Maksimovic, Dragan
This paper introduces a multilevel architecture comprised of interconnected dc to three-phase ac converter units. To enable series connected operation, each converter unit contains a quadruple active bridge (QAB) converter that provides isolation between the dc side and each of the three ac sides. Since each converter unit transfers dc-side power as constant balanced three-phase power on the ac side, this implies instantaneous input-output power balance and allows elimination of bulk capacitive energy storage. In addition to minimizing required capacitance, the proposed approach simultaneously enables simplified dc-link controllers amenable to decentralized implementation, supports bidirectional power transfer, and exhibits a modularmore » structure to enhance scalability. Isolation provided by the QAB allows a wide range of electrical configurations among multiple units in various dc-ac, ac-dc or ac-ac applications. In this paper, the focus is on series connections on the ac side to emphasize multilevel operation, and the approach is experimentally validated in a dc-ac system containing two cascaded converter units.« less
21 CFR 74.1334 - D&C Red No. 34.
Code of Federal Regulations, 2010 CFR
2010-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1334 D&C Red No. 34. (a) Identity. (1) The color additive D&C...-carboxylic acid. (2) Color additive mixtures for drug use made with D&C Red No. 34 may contain only those diluents that are suitable and that are listed in part 73 of this chapter as safe for use in color additive...
NASA Administrator Bolden Volunteers with the DC Cares Program
2009-12-14
NASA Administrator Charles Bolden spent time volunteering with DC Cares at the Park View Recreation Center in Washington, DC for their Santa's Workshop program, Monday, Dec. 14, 2009. Mr. Bolden spoke with students about his experience as a former NASA astronaut and current NASA Administrator, encouraging them to study math and science and to stay in school. Photo Credit: (NASA/Bill Ingalls)
21 CFR 82.1306 - D&C Red No. 6.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 6. 82.1306 Section 82.1306 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF CERTIFIED...) and (b) of this chapter. (b) The color additive D&C Red No. 6 may be safely used for coloring drugs...
21 CFR 82.1307 - D&C Red No. 7.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Red No. 7. 82.1307 Section 82.1307 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF CERTIFIED...) and (b) of this chapter. (b) The color additive D&C Red No. 7 may be safely used for coloring drugs...
21 CFR 82.1307 - D&C Red No. 7.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Red No. 7. 82.1307 Section 82.1307 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF CERTIFIED...) and (b) of this chapter. (b) The color additive D&C Red No. 7 may be safely used for coloring drugs...
21 CFR 82.1306 - D&C Red No. 6.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Red No. 6. 82.1306 Section 82.1306 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF CERTIFIED...) and (b) of this chapter. (b) The color additive D&C Red No. 6 may be safely used for coloring drugs...
21 CFR 74.3602 - D&C Violet No. 2.
Code of Federal Regulations, 2013 CFR
2013-04-01
... coloring absorbable meniscal tacks made from poly (L-lactic acid) at a level not to exceed 0.15 percent by... 21 Food and Drugs 1 2013-04-01 2013-04-01 false D&C Violet No. 2. 74.3602 Section 74.3602 Food and... ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3602 D&C Violet No. 2. (a) Identity and...
21 CFR 74.3602 - D&C Violet No. 2.
Code of Federal Regulations, 2011 CFR
2011-04-01
... coloring absorbable meniscal tacks made from poly (L-lactic acid) at a level not to exceed 0.15 percent by... 21 Food and Drugs 1 2011-04-01 2011-04-01 false D&C Violet No. 2. 74.3602 Section 74.3602 Food and... ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3602 D&C Violet No. 2. (a) Identity and...
21 CFR 74.3602 - D&C Violet No. 2.
Code of Federal Regulations, 2012 CFR
2012-04-01
... coloring absorbable meniscal tacks made from poly (L-lactic acid) at a level not to exceed 0.15 percent by... 21 Food and Drugs 1 2012-04-01 2012-04-01 false D&C Violet No. 2. 74.3602 Section 74.3602 Food and... ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3602 D&C Violet No. 2. (a) Identity and...
21 CFR 74.3602 - D&C Violet No. 2.
Code of Federal Regulations, 2014 CFR
2014-04-01
... coloring absorbable meniscal tacks made from poly (L-lactic acid) at a level not to exceed 0.15 percent by... 21 Food and Drugs 1 2014-04-01 2014-04-01 false D&C Violet No. 2. 74.3602 Section 74.3602 Food and... ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3602 D&C Violet No. 2. (a) Identity and...
21 CFR 74.3602 - D&C Violet No. 2.
Code of Federal Regulations, 2010 CFR
2010-04-01
... coloring absorbable meniscal tacks made from poly (L-lactic acid) at a level not to exceed 0.15 percent by... 21 Food and Drugs 1 2010-04-01 2010-04-01 false D&C Violet No. 2. 74.3602 Section 74.3602 Food and... ADDITIVES SUBJECT TO CERTIFICATION Medical Devices § 74.3602 D&C Violet No. 2. (a) Identity and...
21 CFR 74.1334 - D&C Red No. 34.
Code of Federal Regulations, 2013 CFR
2013-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1334 D&C Red No. 34. (a) Identity. (1) The color additive D&C...-carboxylic acid. (2) Color additive mixtures for drug use made with D&C Red No. 34 may contain only those diluents that are suitable and that are listed in part 73 of this chapter as safe for use in color additive...
21 CFR 74.1334 - D&C Red No. 34.
Code of Federal Regulations, 2014 CFR
2014-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1334 D&C Red No. 34. (a) Identity. (1) The color additive D&C...-carboxylic acid. (2) Color additive mixtures for drug use made with D&C Red No. 34 may contain only those diluents that are suitable and that are listed in part 73 of this chapter as safe for use in color additive...
21 CFR 74.1334 - D&C Red No. 34.
Code of Federal Regulations, 2012 CFR
2012-04-01
... ADDITIVES SUBJECT TO CERTIFICATION Drugs § 74.1334 D&C Red No. 34. (a) Identity. (1) The color additive D&C...-carboxylic acid. (2) Color additive mixtures for drug use made with D&C Red No. 34 may contain only those diluents that are suitable and that are listed in part 73 of this chapter as safe for use in color additive...
NASA Astrophysics Data System (ADS)
Jou, H. L.; Wu, J. C.; Lin, J. H.; Su, W. N.; Wu, T. S.; Lin, Y. T.
2017-11-01
The operation strategy for a small-capacity grid-tied DC-coupling power converter interface (GDPCI) integrating wind energy, solar energy and battery energy storage is proposed. The GDPCI is composed of a wind generator, a solar module set a battery bank, a boost DC-DC power converter (DDPC), a bidirectional DDPC power converter, an AC-DC power converter (ADPC) and a five-level DC-AC inverter (DAI). A solar module set, a wind generator and a battery bank are coupled to the common DC bus through the boost DDPC, the ADPC and the bidirectional DDPC, respectively. For verifying the performance of the GDPCI under different operation modes, computer simulation is carried out by PSIM.
Goldman visits Washington, D.C.
2009-03-24
Stennis Space Center Director Gene Goldman (right) visited Washington, D.C,. last month, where he called on Louisiana and Mississippi leaders to update them on work at the rocket engine testing facility. Rep. Gene Taylor, D-Miss., was among those visited by Goldman on March 24.
On the nonlinear variation of dc conductivity with dielectric relaxation time
NASA Astrophysics Data System (ADS)
Johari, G. P.; Andersson, Ove
2006-09-01
The long-known observations that dc conductivity σdc of an ultraviscous liquid varies nonlinearly with the dielectric relaxation time τ, and the slope of the logσdc against logτ plot deviates from -1 are currently seen as two of the violations of the Debye-Stokes-Einstein equation. Here we provide a formalism using a zeroth order Bjerrum description for ion association to show that in addition to its variation with temperature T and pressure P, impurity ion population varies with a liquid's equilibrium dielectric permittivity. Inclusion of this electrostatic effect modifies the Debye-Stokes-Einstein equation to log(σdcτ )=constant+logα, where α is the T and P-dependent degree of ionic dissociation of an electrolytic impurity. Variation of a liquid's shear modulus with T and P would add to the nonlinearity of σdc-τ relation, as would a nonequivalence of the shear and dielectric relaxation times, proton transfer along the hydrogen bonds, or occurrence of another chemical process. This is illustrated by using the data for ultraviscous acetaminophen-aspirin liquid.
Optimized efficiency of all-electric ships by dc hybrid power systems
NASA Astrophysics Data System (ADS)
Zahedi, Bijan; Norum, Lars E.; Ludvigsen, Kristine B.
2014-06-01
Hybrid power systems with dc distribution are being considered for commercial marine vessels to comply with new stringent environmental regulations, and to achieve higher fuel economy. In this paper, detailed efficiency analysis of a shipboard dc hybrid power system is carried out. An optimization algorithm is proposed to minimize fuel consumption under various loading conditions. The studied system includes diesel engines, synchronous generator-rectifier units, a full-bridge bidirectional converter, and a Li-Ion battery bank as energy storage. In order to evaluate potential fuel saving provided by such a system, an online optimization strategy for fuel consumption is implemented. An Offshore Support Vessel (OSV) is simulated over different operating modes using the online control strategy. The resulted consumed fuel in the simulation is compared to that of a conventional ac power system, and also a dc power system without energy storage. The results show that while the dc system without energy storage provides noticeable fuel saving compared to the conventional ac system, optimal utilization of the energy storage in the dc system results in twice as much fuel saving.